<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="http://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUP4</accession>
    <name>A0A2G4EUP4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000242">
        <property type="protein sequence ID" value="PHX53208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53208">
        <property type="protein sequence ID" value="PHX53208"/>
        <property type="gene ID" value="CP500_022715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8515" checksum="E41585307A3BDD7E" modified="2018-01-31" version="1">MKPNFNEMSKKELRTYVLAHRDDNEAFYAYVDKINAEGNRVTHPPLKSLEDMENYPEFIEKLRRDSGHQESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUY5</accession>
    <name>A0A2G4EUY5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SGNH/GDSL hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000220">
        <property type="protein sequence ID" value="PHX53298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53298">
        <property type="protein sequence ID" value="PHX53298"/>
        <property type="gene ID" value="CP500_022235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="82"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="319" mass="35434" checksum="EBA4524A6CF9CD99" modified="2018-01-31" version="1">MKLALIIVAVTAGFLVAIELLLRVLLGFGNPLIYIPDAECGYLLAPNQRVRRLGNRIEINEYSMRTGAIAPLPPPKTLRVLLLGDSVANGGWWTDEADTISEIMARQLRLQILNLATNAQLHSKVNYSNVEVLNCSANSWGPRNQLAYIKRFGLFGSKVVVLLLNTDDLFTSAPCAAVVGRDRAYPDRKPLMAIGQLLNRYLLPTVPRELVTPSAQNEDKVGSNLEAIRQIKTAANLANIDFVLAMTPKLHELDEIGSHEWEVKARSRLTELVVTEKITYIDFLPIFNSAPEPLTFYRDSIHLSPKGNQLVSQIISKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUZ6</accession>
    <name>A0A2G4EUZ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF928 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000222">
        <property type="protein sequence ID" value="PHX53286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53286">
        <property type="protein sequence ID" value="PHX53286"/>
        <property type="gene ID" value="CP500_022300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010328">
        <property type="entry name" value="DUF928"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06051">
        <property type="entry name" value="DUF928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013922127" evidence="2">
        <location>
            <begin position="26"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="261" mass="28621" checksum="97C98B7352984C30" modified="2018-01-31" version="1">MKKLTKFLINLTSVGSIVLIATLNASQFAVVGQPTPQVDGKPITQSGGPRFSQPTEDNQSPIDGDSGKVTRKATPCEKGKIKLTPLVPKNKIGRTVSEYPVFFFYLPQTDAKQAEFILEDENRQQIYQTTLNINNSSGVIRVSIPTNKNVSPLQIDKNYTWSIALICDDIDRSADVLEKGIVRRVELSADIRSQLQKADPRLKAVIYAQTGIWQDALSTLVAARLANPNDADLAADWKILLDSVNLGEIVAEPIAPIEPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV69</accession>
    <name>A0A2G4EV69_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NAD-dependent malic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_021820</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000206">
        <property type="protein sequence ID" value="PHX53378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53378">
        <property type="protein sequence ID" value="PHX53378"/>
        <property type="gene ID" value="CP500_021820"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00058">
        <property type="reaction ID" value="UER00102"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05311">
        <property type="entry name" value="NAD_bind_2_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045213">
        <property type="entry name" value="Malic_NAD-bd_bact_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="8">
        <location>
            <begin position="14"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="464" mass="49501" checksum="D682E8BF68957F06" modified="2018-01-31" version="1">MTVKLTPNPSFSLTIRVVLPNQPGMLAGVISAIGSVGGNFGQIDLIEQTRATTIREINVDASSTEHSEEIVQAVKALPDIKVLDVYDRTFHLHRGGKIRVESKISLKRQSDLAMAYTPGVGRICTAIANDPQQVYNLTIKQNTVAIVTDGSAVLGLGNLGPMAALPVMEGKAMLFKEFAGIDAFPICLNTQDTEEIIRTVQNIAPVFGGVNLEDISSPRCFEIEARLRETLDIPIFHDDQHGTAIVSLAALINALKVVQKSMSEVCIVINGAGAAGVAIARLLRKAGAENIIMCDSKGVLSKDRTDMNPEKLEFAVASSGTLEDAIAGADVFLGVSAPGVLTRSMVRSMAENRIVFAMANPIPEIQPELIMDDVAIIATGRSDYPNQINNVLAFPGIFRGALDCKAATITTNMYLEAAYAIASLVNPSKLDKEYIIPSVFDDRVATAVASAVQLAARAEGIARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVF2</accession>
    <name>A0A2G4EVF2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000186">
        <property type="protein sequence ID" value="PHX53509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53509">
        <property type="protein sequence ID" value="PHX53509"/>
        <property type="gene ID" value="CP500_021105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="298" mass="34251" checksum="AE48910FE59222C0" modified="2018-01-31" version="1">MKSLNSEQQHIFVKTNNIRLHCVAQGEGELVLLLHGFPEFWYSWRHQIPALARHFKVVVPDLRGYNDSDKPESGYDLDTLSADIRGLIDRLGYTKAHIVGHDWGGVIAWHLAQKFPEKINRLAILNAPHPQRFVQEMASNLDQLRRSWYVFAFQVPGIPEWLIQQNLKNFVHNVFQGQAIRKGAFSAEETKIYQTALEKPGVLAAAVNYYRQIFHPERLWNLGQKWETVNVPTLVLWGEEDAFLSQKLVEDLDRLITAPFKLKLVPNCGHWIQQEVPQTVNRELLSFLRSSSGSLVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVR3</accession>
    <name>A0A2G4EVR3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional aldolase/short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000170">
        <property type="protein sequence ID" value="PHX53631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53631">
        <property type="protein sequence ID" value="PHX53631"/>
        <property type="gene ID" value="CP500_020485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="19"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="661" mass="71551" checksum="AB67EDFB7371C885" modified="2018-01-31" version="1">MKSLWNDLEAQQYPDDLALRVYTSRLLGREPALVLHGGGNTSVKIRETNIVGEAEDILYVKGSGWDLATIEAAGFSPVRIPHLLKLAQLESLSDPQMVNELKTQMTRASAPSPSVETILHATLPYKYVDHTHADAVITITNTANGFDRIHEIYGDRLVVIPYVMPGFDLARLCAQKFVADATEKTVGMVLMNHGLFSFGETARESYERTIELVSLAEDYLRKHGASNPPSAQATATPEDKPLRHSLAQLRHQLSQSAGFPIILATHRHPKTLAYARRDDISTISQQGPLTPDHVIRTKRVPMLGRDVEGYIAAYKAYFQAHAAANLTMLDPVPRVILDPDFGMCTVSQTAKQAQIVADIYDRTIDAIESATLLGGYQALSPKDIFAVEYWDLEQAKLRQGGKPPAFTGEVALVTGAASGIGKACVDSLLKRGAAVVGLDINPQIESLYSRADFCGITCNVTDESAIMAALERAIQKFGGLDILVLNAGIFPASRSISQLGSDEWRKVMSINLDANLVLMRECHPFLKLAPKGGRVVVIGSKNVPAPGPGAAAYSASKAALNQLVRVAALEWGGDRIRINSLHPNAVFDTGVWTVGANGYSPLESRAKHYGLTVEEYKTNNVLKVEVTSHSVAELAAELCGDLFANTTAAQIPVDGGNDRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVS8</accession>
    <name>A0A2G4EVS8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M23 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000169">
        <property type="protein sequence ID" value="PHX53635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53635">
        <property type="protein sequence ID" value="PHX53635"/>
        <property type="gene ID" value="CP500_020440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013599317" evidence="1">
        <location>
            <begin position="30"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="95"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="358" mass="38619" checksum="34D60A165F845C7E" modified="2018-01-31" version="1">MILLSKKHISTILLAFGLTSILGCATKTAVNVPLVEANAIAQNLVSTVAQQPNSPKFGQPIGCTLGKDCFILLYFDRDPSPAAVDFGCGRQTYDGHDGTDFAIPDAKAMAKGVPVIASAAGKVLRVRDGVVDQRLQNETDKANVAGTECGNGMVIDHGGGWEAQYCHLRQGSVVVKSGAQVAKGAVLGMVGNSGKASFPHVHVTFRYQGKAVDPFVGINPKLGCNVARNPIWDRPLDYVSTGLIRAGFANQQPDMNAVWEGQFAETKLAVNIPALLFWVQSYGVLKGDREKYQLFAPNGKTIINNTSEIKAPSRTWLSSIGKRNSTNSPLTPGVWRAEYRLTRGDRVLVEVKREVELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVT5</accession>
    <name>A0A2G4EVT5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PrsW family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53566">
        <property type="protein sequence ID" value="PHX53566"/>
        <property type="gene ID" value="CP500_020710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026898">
        <property type="entry name" value="PrsW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13367">
        <property type="entry name" value="PrsW-protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="28"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="441" mass="47766" checksum="ACF9531A9F0EA6EB" modified="2018-01-31" version="1">MGFLRQVPAQGAMGATASKYQLSEIMEVAIGRDQSCQIALESIAYGMVSRRHATVRPVTTGNFPQWEVCDLNSANGTYVNGTKLQGCQTLETGDRISLGLDGPEFIFETTLNKSQNQPRFPTANQSFSNASEKEGLTFTQLFPIASTGKQLSQKAYLYPGIATVIFVISMFLAVGNSATFNFLLAAYLSGAAYYFIYQLCGKHKPWWILFGSALATVLILLSPLLIGFIIVFREILPGSLPAEGEQISFWAFLIRMFFGAGLMEELLKALPVLGAMLLGNLLRNPWRDRIGVWEPLDGILLGSASAVGFTLLETLGQYVPNIIQNVTLQAGPDAGELVGLQLLIPRILGSVAGHMAYSGYLGYFIGLSALKPKKRWQILGVGYLTASALHALWNASGSASVLLLAVVGVLSYAFLVAAILKARALSPNRSQNFATRIFSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVW7</accession>
    <name>A0A2G4EVW7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_020215</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000163">
        <property type="protein sequence ID" value="PHX53683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53683">
        <property type="protein sequence ID" value="PHX53683"/>
        <property type="gene ID" value="CP500_020215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013807758" evidence="2">
        <location>
            <begin position="23"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="3">
        <location>
            <begin position="243"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="MurNAc-LAA" evidence="4">
        <location>
            <begin position="489"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="608" mass="66009" checksum="0466D155521022B0" modified="2018-01-31" version="1">MKKFLGLVVFGMILAIASVAVAAQPLFVAYPPANHQTTVDRIFLIGTAPPAGQVSVNGNQISRTAAGHFAPTFPLQLGENVFALRYQNQEVKIKVTRQPNQPQVPVGLAFAKDSLTPKVDMASLPGEYICFGAIAPTNAQVVVKLADVTIPLKARSQVELPDNKSVLLGENSPIKNGGGEQYQGCAKTPPNPSLPRGGNESNSQLPNGKKVDLGVPVFELTMNNQTVSQTGTGKISILSPAELEIAEVTAEPGVARTGASTDFSRMTPLPKGTRATIIGREGEWVRLDYGAWIKASEVRIVKDAVPVRSLIRSARSRQIPGWTEVLFPLEIPVPVTVQEAAGNFTLTLYNTTAQTDIIRLDDDPVISRLTWQQISPLQVQYTFNLKSVQQWGYKLRYDGTTLVLSLKHPPVKAGKIPVSPEKPLSGIKILLDPGHGGPEDSGGVGPTGYREKTVALIVSKLVRSELVNRGANVVMTRVEDVDLDLLPRVEMIQKEEPAIAISIHYNALPDNGDAINTKGVGAFWFNPQSHSLAIFLQNYLVAKLNRPSYGVFWNNLALTRPTVAPSVLMELGFMINPDEFEWIVNPTEQKKLAEAMAQGITEWFASVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVX5</accession>
    <name>A0A2G4EVX5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000164">
        <property type="protein sequence ID" value="PHX53669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53669">
        <property type="protein sequence ID" value="PHX53669"/>
        <property type="gene ID" value="CP500_020220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036700">
        <property type="entry name" value="BOBF_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101756">
        <property type="entry name" value="SSF101756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="143" mass="15914" checksum="896FA347C4AA1DF0" modified="2018-01-31" version="1">MTNAIYQIYIQKFSLGSLLLILASGFLGCGNLPNSQFNLGFNTAKISDVQQKRQVDTEVYLQGKVENRAPFVGNAAYQLQDTTGSIWVLTKQALPQLGDEILVKGKVRYQSIKLKDLAGKDLGEVYIEETEQLKRTPNSDKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVZ8</accession>
    <name>A0A2G4EVZ8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_020075</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53701">
        <property type="protein sequence ID" value="PHX53701"/>
        <property type="gene ID" value="CP500_020075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037215">
        <property type="entry name" value="GUN4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140869">
        <property type="entry name" value="SSF140869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="15"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="354" mass="39188" checksum="172CC5D70632065A" modified="2018-01-31" version="1">MQHWAKGQQLHEGEYLIEEILGGGGFGVTYRAQNRKKGKLVAIKTLNAIQQGKADFVKRQEKFMNEALCLAKCHHPHVVEVYEVFQEGDLWCMVMELLDGTNLAEYLEDNGILSEEKALPIIQQVGNALSFVHKQGFTHQDVKPQNIMLRTPPAPLGKGGERENYSFAKGGEISSPPLTKGGQGGAVLIDFGLARQATVPGKLRTNSNSGTECFAPLELLEKRAEFGAYTDVYSLAATLYVMLTGELPFPSQFRKQNIPLIPPKQHNNKISDRVNAAIIKGMELEPQNRPQSVQEWLDLVMPKQAANEVQLVSAVGMDYINLRNLLAAGKWKEADQETARVNTSVPVKPFLISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWA2</accession>
    <name>A0A2G4EWA2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Histidine biosynthesis bifunctional protein HisIE</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <shortName evidence="15">PRA-CH</shortName>
                <ecNumber evidence="15">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Phosphoribosyl-ATP pyrophosphatase</fullName>
                <shortName evidence="15">PRA-PH</shortName>
                <ecNumber evidence="15">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">hisI</name>
        <name evidence="15" type="synonym">hisIE</name>
        <name evidence="17" type="ORF">CP500_019480</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5 15">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 15">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 15">In the C-terminal section; belongs to the PRA-PH family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 15">In the N-terminal section; belongs to the PRA-CH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="15"/>
    <dbReference type="EC" id="3.6.1.31" evidence="15"/>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53801">
        <property type="protein sequence ID" value="PHX53801"/>
        <property type="gene ID" value="CP500_019480"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11534">
        <property type="entry name" value="NTP-PPase_HisIE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01021">
        <property type="entry name" value="HisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01019">
        <property type="entry name" value="HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023019">
        <property type="entry name" value="His_synth_HisIE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026660">
        <property type="entry name" value="PRA-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 15" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11 15 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRA-CH" evidence="16">
        <location>
            <begin position="40"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-AMP cyclohydrolase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-ATP pyrophosphohydrolase" evidence="15">
        <location>
            <begin position="128"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX53801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="216" mass="24288" checksum="BEFB97A103020A25" modified="2018-01-31" version="1">MSANDLSSLSRSIPIEKIRYDDRGLVPAIVQDYLDGTVLMMAWMNRDSLQKTLETGQTWFWSRSRAEFWNKGATSGHIQNVKGLRYDCDSDALLVTVEQVGDIACHTGERSCFHQVDGEISPPPGDMLSQLFDVICDRRDNPNESSYTCKLFEGGDNKILKKIGEESAEVVMACKDDDKDGIAGEVADLFYHALVAIAHHQVDLRDVYRKLGDRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWC4</accession>
    <name>A0A2G4EWC4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000150">
        <property type="protein sequence ID" value="PHX53833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53833">
        <property type="protein sequence ID" value="PHX53833"/>
        <property type="gene ID" value="CP500_019345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="11819" checksum="6266B3DFFCC4971E" modified="2018-01-31" version="1">MKELKVPTSRSYHEYLISSLKNPESAASYIEVMLELESETPEPELLRAGLKDVVDAYLQINKLSTEAKLIYEKFDRMLSESGGEEIYALIVLLDKLGLQLAVAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWG7</accession>
    <name>A0A2G4EWG7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF262 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000152">
        <property type="protein sequence ID" value="PHX53818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53818">
        <property type="protein sequence ID" value="PHX53818"/>
        <property type="gene ID" value="CP500_019430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="2">
        <location>
            <begin position="44"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="366" mass="43290" checksum="04BC83BB631E1A15" modified="2018-01-31" version="1">MAKAPKTPLETEITHEQREAAEAEIREKQKTVDYDTKEYPVEVLVQKYRDGLDEDISELYIPDYQRELIWEEPRQSKFIESIFLGLPIPYIFVADLRPKQEDDEDDLARLEIVDGTQRIRTLDRFLNNELKLSELEKLKNLNNFKFTDLPLARQRRFNRATIRMIVLTEKADEETRRDMFERINTGSVQLNDMEKRRGISPGPFVNLLEELAKTPKFIKLCPLSDALVRKREPEEFVLRFFAYLNNYQKFDKRVNEFLNEYLEKNNNDKMNLDGMRSEFDKMLDFVEKYFSNGFSKSKGHVKTPRIRFEAISVGVALALREKSDLVPKSMTWLDSPEFKEYTTSDASNSKPKVIKRIEYVRDELLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWI6</accession>
    <name>A0A2G4EWI6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Asparagine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Asparaginyl-tRNA synthetase</fullName>
            <shortName evidence="5">AsnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">asnS</name>
        <name evidence="7" type="ORF">CP500_020945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000181">
        <property type="protein sequence ID" value="PHX53537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53537">
        <property type="protein sequence ID" value="PHX53537"/>
        <property type="gene ID" value="CP500_020945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="6">
        <location>
            <begin position="135"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="463" mass="52746" checksum="3E90B6121150BE55" modified="2018-01-31" version="1">MTNQRIAAILRGGEPEETVTVQGWVRTKRELKEFAFVEVNDGSAMANLQVVINADLPDFENVLKQLNTGASLEVSGVLVASPAKGQRIELKASAVQVYGDADPQTYPLQKKRHSLEFLRTIAHLRPRTNTHGAVFRVRNACSAAIHQFFQERGFLWVHTPIIAASDCEGAGEMFAVTNFDLKNIPRNDSQEVDYAKDFFGKRAYLTVSGQLEAEIMAMAFGNVYTFGPTFRAENSNTSRHLAEFWMIEPEMAFCDLQGDMDLAEAFLKYIFKYVLDHCPEDMEFFNERIDQTVLATAENIINNQFERITYTEAIALLEKADKKFEFPVNWGLDLQSEHERYLAEELFQKPTIVSDYPVGIKAFYMRLNDDEKTVRAMDILAPKLGEIIGGSQREERLDVLQKRMEAQGMNQEELWWYLDLRRYGTVPHAGFGLGFERLVQFMTGMGNIRDVIPFPRAPLSIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWL7</accession>
    <name>A0A2G4EWL7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53567">
        <property type="protein sequence ID" value="PHX53567"/>
        <property type="gene ID" value="CP500_020715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="6712" checksum="A7639BFC732B26A5" modified="2018-01-31" version="1">MMAGTPKSGLLLALSCITAIAAVGSVFELSSGEAQLGTVVTGIILALSVPLTGIFFYAAVQDARANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWN5</accession>
    <name>A0A2G4EWN5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="8">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisS</name>
        <name evidence="10" type="ORF">CP500_018690</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53955">
        <property type="protein sequence ID" value="PHX53955"/>
        <property type="gene ID" value="CP500_018690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="1"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="425" mass="47409" checksum="37A67BD364BEA867" modified="2018-01-31" version="1">MNSIKTLPGTRDILPDEIQYWQNVEEIARTILKKAAYREIRTPIFEQTSLFERGIGEATDVVGKEMYTFKDKGDRSSTLRPEGTAGVVRAFIQNSLYAQGDVQRLWYTGPMFRYERTQEGRQRQFNQIGVEVLGSANPRADVEVIAIACDILQTLGLKNLHLDINSVGNKEDRQNYRQALIDYFTPFKSELDADSQDRLTRNPLRILDSKNERTQEIVTGAPSILDYLGDESRSHFEQVQLMLTNLGISYQLNPRLVRGLDYYTYTAFEIISDDLGAQATVCGGGRYDGLVKELGGPDTAAVGWAMGVERLIILLQKLQPLPAPKLDFYLVSRGDKAEQQSVLLAQKLRGAGFSVEIDLSGSAFGKQFKRADRSGAVACLVLGDAEAENETVQLKWLASGEQSAIAQSELLAMTDELQQKIMAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWS3</accession>
    <name>A0A2G4EWS3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-carotene hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000133">
        <property type="protein sequence ID" value="PHX53995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53995">
        <property type="protein sequence ID" value="PHX53995"/>
        <property type="gene ID" value="CP500_018485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="PTHR19353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="2">
        <location>
            <begin position="47"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="296" mass="34653" checksum="7419D5DFD6234B42" modified="2018-01-31" version="1">MSEAGRPLTVPREFLSPPGDFNPTLLLFLSAVAIIVISYFGFWNWEWPQWCCFSLNVLALHMAGTVIHDASHHAAHRDRTINAILGHGSALMLGFAYPVFTRVHMQHHAHVNDPENDPDHYVSTGGPLWLIAARFFYHEIFFFKRKLWRKHELWEWFFSRLFVIGVVYISIQYDQLGYVLNFWFSPALVVGLALGLFFDYLPHRPFHERDRWKNARVYPSPILNILILGQNYHLIHHLWPSIPWYNYKPAYEAVKPLLDEKGSPQSLGILEGKKDFWSFIYDIFLGIRLHHKKASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWW3</accession>
    <name>A0A2G4EWW3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53956">
        <property type="protein sequence ID" value="PHX53956"/>
        <property type="gene ID" value="CP500_018700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10199" checksum="9F79357029D80117" modified="2018-01-31" version="1">MSRSVSQTPVTLSDRELQVVELVATGLTNEKIAEKLEISKRTVDNHISNILNKTRVDNRVTLVRWALQWGKVCLDNINCCPLPGPIDKEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX54</accession>
    <name>A0A2G4EX54_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Putative manganese efflux pump MntP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mntP</name>
        <name evidence="9" type="ORF">CP500_018135</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Probably functions as a manganese efflux pump.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MntP (TC 9.B.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000128">
        <property type="protein sequence ID" value="PHX54058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54058">
        <property type="protein sequence ID" value="PHX54058"/>
        <property type="gene ID" value="CP500_018135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01521">
        <property type="entry name" value="MntP_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003810">
        <property type="entry name" value="Mntp/YtaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022929">
        <property type="entry name" value="Put_MntP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35529">
        <property type="entry name" value="PTHR35529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02659">
        <property type="entry name" value="Mntp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="193" mass="20416" checksum="FBB843B7408877AB" modified="2018-01-31" version="1">MDAATTVLLSLGLAADAFAVSISSGLAIKHMKVNKALKIALFFGGFQALMPVVGWFVGLSFSFLISAIDHWIAFGLLSFIGGKMIYESLQNDECEKKFNPLDTGTLITLSVATSIDALAVGIGFAVLKDSIAPAVTAIGFITFFLVFAGVFIGHKCGNLFANKIEILGGAILIFIGSRILFLHLTELPVITNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXI7</accession>
    <name>A0A2G4EXI7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4079 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54262">
        <property type="protein sequence ID" value="PHX54262"/>
        <property type="gene ID" value="CP500_017160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025067">
        <property type="entry name" value="DUF4079"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13301">
        <property type="entry name" value="DUF4079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="145" mass="15648" checksum="8325965ED2C85343" modified="2018-01-31" version="1">MNLPSFLWLWKIAAWSMGFSLFAYLLLAVTGTWMFAARNTKQPRPQWLRPFHLATGAGMATLVILLLGIGVVGTLGEYGKLGHSAHLPVGLAVVTLVLVSVGSGLQISPKNPWARPLHIGANLTLFGGFGLVLLTGWTIVQKYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXK3</accession>
    <name>A0A2G4EXK3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Phosphoenolpyruvate synthase</fullName>
            <shortName evidence="10">PEP synthase</shortName>
            <ecNumber evidence="6 10">2.7.9.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Pyruvate, water dikinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_017385</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:11364"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.2" evidence="6 10"/>
    <dbReference type="EMBL" id="NXIB02000115">
        <property type="protein sequence ID" value="PHX54206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54206">
        <property type="protein sequence ID" value="PHX54206"/>
        <property type="gene ID" value="CP500_017385"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000854">
        <property type="entry name" value="PEP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01418">
        <property type="entry name" value="PEP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="33"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="11">
        <location>
            <begin position="404"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="13">
        <location>
            <begin position="501"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00021623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX54206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="825" mass="90767" checksum="4728A33FDA7E6F91" modified="2018-01-31" version="1">MSERLAIQQKQLLIPKEKALILWFDEVGIADIPLVGGKNASLGEMIQQLTPKGVNVPNGFATTAHAYRCFIESAGLEAKLREIFADLDVEDVNKLRQKGKQARTLILDTPFPEDLQIAIAQAYNQLCDRYGDNTDVAVRSSATAEDLPDASFAGQQETYLNVHACNGVIQCCHKCFASTFTDRAISYRQLRGFDHFEVALSVGVQKMVRSDLASSGVMFSIDTETGFKNAALITAAYGLGENIVQGAVNPDEYLVFKPTLKQGFRPILDKRLGTKQIKMVYDIGGSKYTKNVSVQPAEREKFAINDDEVLQLAQWAVLIEEHYSQVRETYTPMDIEWAKDGNTGELFIVQARPETVQSQKSATVLRSYKLQGSSAVLVKGRAVGEAIGQGKARVILDANEIGEFEAGEVLVTNKTDPDWEPIMKKASAIVTNSGGRTCHAAIIAREMGIPAIVGTGDATKVLKNGQEITICCAEGEEGKVYSGLVPFEVQESAIDNLPRPRTQILMNVGNPEEAFGLSAIPCDGVGLARLEFIIANHIKAHPLALIHFDELTDESVKRQIAKLTALYEHKPDFFTDKLAHGIATIAAAFYPNPVIVRMSDFKSNEYANLLGGRQFEPKEENPMIGWRGASRYYDPNYREAYALECKALKRVRDEMGLTNVIPMIPFCRTPDEGRKVLAEMAKHGLVKGENGLQVYVMCELPSNVIFADEFAQVFDGFSIGSNDLTQLTLGLDRDSGLVAHIFDERNEAVKRLVEIAIKAAKKYDRKIGICGQAPSDYPEFARFLVELGIDSISLNPDSVLKTLLDVAKVEASTSMMDLVMDVAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXS7</accession>
    <name>A0A2G4EXS7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endoglucanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000110">
        <property type="protein sequence ID" value="PHX54286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54286">
        <property type="protein sequence ID" value="PHX54286"/>
        <property type="gene ID" value="CP500_016890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024745">
        <property type="entry name" value="Glyco_hydro_44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12891">
        <property type="entry name" value="Glyco_hydro_44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_44" evidence="3">
        <location>
            <begin position="102"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="562" mass="62722" checksum="C1DB9E24F6D24157" modified="2018-01-31" version="1">MNPRFLWQSPENKPRWLVLFLLGLIAAFGIVVTTAYIKNSIAQTSSLALSVDVTADRHSISPDIYGMNDYALDPALAQELRIPVERWGANHTSRYNWLVDSSNSGDDFFFMGGGDNKNPIPGDSIDKIVKTNRKNGSKSIVTIPMIGYVNKLSIWNCGFRVSKYGPQEKTNPYIFPEGDKCGNGKRPDGTLITNNNRLDVSIVSNPEFQKPWVQHLVKTHGTAANGGVQIYQMDNEPSGWGNTHRDVHPEATSYDELRDRTYQYASMVKSTDPTAKVLGPSDFGWPVYVDSGVKGDREKHGGVWFARWYLQQMRAYEQQKGVRILDYFDEHYYPSADEGCLANCPAGDAKTQAARLRSTRSLWDSTYTDESWIGKYNPPLTIIPRFRQWIKEDYPGTKLAITEYNWGGLESMNGALAQADILGIFGREQVDLATLWGPPKSSEPTAYTFRMYMNYDGKGGKYGDTWVRSHSTDQGLLAIYGADRTSDGTLTLVIINKTGKNLTSNLSLKGFKPAAKAQVYTYSEANLRAIVRQSDLDISATGFQATYPANSMTLVAIPKANY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXV2</accession>
    <name>A0A2G4EXV2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54280">
        <property type="protein sequence ID" value="PHX54280"/>
        <property type="gene ID" value="CP500_017060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_33" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="44" mass="5396" checksum="A0FB403202DB5D78" modified="2018-01-31" version="1">MLEHLKWRFQGNFDTDLFSHQAIDNQKENQIQMYLHCQKSHVVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXX7</accession>
    <name>A0A2G4EXX7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4276 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54017">
        <property type="protein sequence ID" value="PHX54017"/>
        <property type="gene ID" value="CP500_018450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025455">
        <property type="entry name" value="DUF4276"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14103">
        <property type="entry name" value="DUF4276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="27081" checksum="0BA9171D8953D163" modified="2018-01-31" version="1">MVREIRIYIEGIGDESEDESTTENVPQIRPGFRSKIPAGKETTAGLRAGFAHLFKELYDLAESKGIKILSIMSGSRRDACQDFLISLEYYPDAFNVLLVDSESLVSETHTPWEHLRSRKDDQPWILATQGLDDACCHLMVQTMEAWFIADIDALSKFYNGGFKEDYLHQRLGNQSVEKVSKYNLSQWLKSATNKTSKGKYHKTGHAPKLLALLDVDKVRKASPSCDRLFTTITKIIEMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXZ2</accession>
    <name>A0A2G4EXZ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54348">
        <property type="protein sequence ID" value="PHX54348"/>
        <property type="gene ID" value="CP500_016615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="85" mass="9725" checksum="548985ECFCC9764A" modified="2018-01-31" version="1">MNTEVDELEDELRPEYDFSNMAGGVRGKYVERYRTGTNVVLLDPDVAKAFPTNASVNEALRLLLQIAQRQQPEQTRLERTDSLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXZ8</accession>
    <name>A0A2G4EXZ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54415">
        <property type="protein sequence ID" value="PHX54415"/>
        <property type="gene ID" value="CP500_016360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="191"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="261"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="595" mass="62289" checksum="A3A268D9AA7C7CF4" modified="2018-01-31" version="1">MTNQVISEAEETQPLHQIQNGRNSNEAVKVPENGVKDDSRREFSSSEEEREISALVPEMDAEEAVIWEEEETEVPNRKGIRWPAVLAGVGIGVAATLAGVYLVSGKSAGPAATVPAPQAPTSQTVTVALVESVEVAQALEATGTVAAYDLLPVLPQANGLQIKQVLVAEGDRVEKGQVMAVLDDSVLRSQIAEAVAKVQSADSTVEQAQAQVQQAQSAQQEAQAGVDGAQAGVEKAIADVAQAKTGVGQAKAGVEQAKAGVEQARAGIASAQAKLDQAQREVNRTQDLASQGVISQQDLEKRKTERLTAVQDLNKTKADLNKALEEQNKAAEEVRSAVAKVATAEANISTARAALSSARAKVNTAASSVSSARANVGNNAAGVRSNDAQVKKLQIQLEQTVVRAPDGGTVAERIGRVGDVSAGSQKLFSIIRGNKLELQLKVPETQLSQVRPGTAVNISSDSDRRIKLAGTVRDISPLVDPQNRQATVKIDLPQSEFLRSGMFLRGSISTATTQGLKVPAKAILPQSDGGALVYKLVGEDKVLAQPVQVGEISGGAVGDLTDAKVEVKKGLKVGDRVVVDGAGYLKDGDRVKVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY04</accession>
    <name>A0A2G4EY04_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016560</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OprB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54366">
        <property type="protein sequence ID" value="PHX54366"/>
        <property type="gene ID" value="CP500_016560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038673">
        <property type="entry name" value="OprB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013425419" evidence="2">
        <location>
            <begin position="29"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="3">
        <location>
            <begin position="175"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="648" mass="68154" checksum="1D609B77FFCDF98B" modified="2018-01-31" version="1">MNRSFWNLLLVSPAILGLSTVTCGGAIAVEATATAVANQLAAAQPSESIAALVTEPVAETVAATPAASEILAINSSSATAAPASEPAIAQATDANSTEKLAKVEPDTSSAAVALPQASDLAVQTSLNQAGKTQLPTAAKVEIAQTAPAELSNPIVPAAPQAISTEESGAMSQVTSVSQLSDVRPTDWAFQALQSLVERYGCIAGYPDGTYRGNRALTRYEFAAGLNACLDQVTKLISSSTGTFVTKDDLAVLQKLQESFAVELATLRGKVDALEARTAELEANQFSTTTKLRGEVIFTASDSFGNGVKLNDDKTSTTFGYRVRLNFDTSFTGKDLLRTRLQAVNLPNYGAATAAGTNMARLGVDGDSANAFNLDKVFYRFPVGNATVWLGPKGLNLDDIAPLTTPFGDGGNGSISRFGRYNPAIFRGPEGAGAAVNYNLSNTLKATVGYLASDGDAPNPISSRGVFDGSFSAIGQLNLSLGKAFDVGASYVRKYNRTGDVGIMGSTGSSLANRPFGQAGTGSDNFGVQVNFKPSSRFQLGGWYGYTKAEQLRNSNRDATIQNAAVTLALPDFGRKGNLLGFVFGIPPKVTSSDVAKDKDTSYHVEGFYRFQVNDFISVTPGVYVIMNPEHNNKNDDIWVGVLRTTFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYC9</accession>
    <name>A0A2G4EYC9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000094">
        <property type="protein sequence ID" value="PHX54529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54529">
        <property type="protein sequence ID" value="PHX54529"/>
        <property type="gene ID" value="CP500_015650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="12"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="233" mass="25945" checksum="24C5F9BC1CCFA76B" modified="2018-01-31" version="1">MLFRQLFDRESSTYTYLIADRDSAEALLVDPVLEQVERDLQLLKELGLTLRYCLETHVHADHITSASQLRETTGCVSVVPAQAQVNCADRFIHPGETLQVGTVEVQAIATPGHTDSHMAYLVNGTHLLSGDALFIRGCGRTDFQSGDAGTLFDSVTQRLFTLPDSTSIYPGHDYRGQTVSSIEEEKRWNPRFVGRSRDEFIQFMNALNLPNPQKMMEAVPANERCGNLTSILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYD1</accession>
    <name>A0A2G4EYD1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">ATP phosphoribosyltransferase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hisZ</name>
        <name evidence="8" type="ORF">CP500_015610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heteromultimer composed of HisG and HisZ subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000094">
        <property type="protein sequence ID" value="PHX54521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54521">
        <property type="protein sequence ID" value="PHX54521"/>
        <property type="gene ID" value="CP500_015610"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00125">
        <property type="entry name" value="HisZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004517">
        <property type="entry name" value="HisZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00443">
        <property type="entry name" value="hisZ_biosyn_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="7">
        <location>
            <begin position="23"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="411" mass="45870" checksum="152F1AC957751705" modified="2018-01-31" version="1">MVHQPPSGARDLLPLDVAQKISIERRLQQVFHRWGYHRIITSTLERLETLMAGGAIDRSTLIKLQDAEDGELGLRPELTVAIARATVMRMGKTPWQPQRLYYNANVFRKSPDTHSGGQQEFYQTGVELLGSGGTIADAEVLLLLSECLQALEIDDWHLVIGEAGLTATLLEPFPLNVRSQVRGAIANLDRIGLENLPLSTELRERALLLFDLRGRPEDVFPIVAKLDLDLPQQAALNNLKSAIELLYQCQSKIPNLKSHIHLDLSLIQTFDYYTGIVFEVVSSPKTGQRVLGQGGRYDRLLGLFDPQGQNHPGIGFCLNIEDLHQILLSEGLLAKETPASDFLVVPQTSEAAAAAFVYARKLRESSDLVRVEMDLESRETLEEVREYARDRRIAQIAWVNAEGLPTIETVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYF3</accession>
    <name>A0A2G4EYF3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">RuBisCO chaperone RbcX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rbcX</name>
        <name evidence="9" type="ORF">CP500_015695</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">An RbcL-specific chaperone. The central cleft of the RbcX homodimer (RbcX2) binds the C-terminus of an RbcL monomer, stabilizing the C-terminus and probably preventing its reassociation with chaperonin GroEL-ES. At the same time the peripheral region of RbcX2 binds a second RbcL monomer, bridging the RbcL homodimers in the correct orientation. The RbcX2(2)-bound RbcL dimers then assemble into the RbcL8 core (RbcL8-(RbcX2)8). RbcS binding triggers the release of RbcX2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. Interacts with the exposed C-terminal peptide of RbcL via its central cleft, contacts a second RbcL monomer via its peripheral polar surface.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Carboxysome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="8">Most protein is cytoplasmic, but some is in the carboxysome.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The homodimer has 2 functional domains, a central cleft essential for production of soluble RbcL in which the RbcL peptide binds, and a polar surface which plays a role in correct RbcL subunit arrangement.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RbcX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54508">
        <property type="protein sequence ID" value="PHX54508"/>
        <property type="gene ID" value="CP500_015695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110102">
        <property type="term" value="P:ribulose bisphosphate carboxylase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00855">
        <property type="entry name" value="RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038052">
        <property type="entry name" value="Chaperonin_RbcX_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003435">
        <property type="entry name" value="Chaperonin_RcbX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046381">
        <property type="entry name" value="RbcX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791">
        <property type="entry name" value="PTHR33791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02341">
        <property type="entry name" value="RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158615">
        <property type="entry name" value="SSF158615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="4 8" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="5 8" id="KW-1282">Carboxysome</keyword>
    <keyword evidence="3 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="137" mass="15735" checksum="3B1407B30AE8603E" modified="2018-01-31" version="1">MDLKQVAKDTAKVLASYLTYQSVRIVIAQLSETNPPLAIWLNEFSTKGKIQDGELYIRELLLENQDLGFRIMTVREYLAHDVTEFLPEMVRTGIQQSNMEHRRQHLERITQLNWSVATSNPETSSIDSEPNLDNLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYP1</accession>
    <name>A0A2G4EYP1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="6">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="6">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rdgB</name>
        <name evidence="8" type="ORF">CP500_016805</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54297">
        <property type="protein sequence ID" value="PHX54297"/>
        <property type="gene ID" value="CP500_016805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="149"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="177"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="21319" checksum="2CBEAC15CE863DCC" modified="2018-01-31" version="1">MTDRKLLIVATSNPGKLKEMQAYLQDLGWELQLKPEELEIEETGETFIANACLKASEIAKATGEWSIADDSGLMVDALDGQPGIYSARYGSSDADRISRLLRELGGEQNRQAQFVCAIAIARPDGTIALQVEGICHGEILHSPRGTGGFGYDPIFYVPAQQQTFAEMTPEIKRSYSHRGQAFQALLPQMETIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYR6</accession>
    <name>A0A2G4EYR6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosyl hydrolase family 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_014995</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan biosynthesis; glycogen metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphorylase b kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54630">
        <property type="protein sequence ID" value="PHX54630"/>
        <property type="gene ID" value="CP500_014995"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00163"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005977">
        <property type="term" value="P:glycogen metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045583">
        <property type="entry name" value="KPBA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008734">
        <property type="entry name" value="PHK_A/B_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10749">
        <property type="entry name" value="PTHR10749"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19292">
        <property type="entry name" value="KPBB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_15" evidence="5">
        <location>
            <begin position="10"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="KPBB_C" evidence="6">
        <location>
            <begin position="836"/>
            <end position="1068"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1069" mass="121659" checksum="6FDA24AB584EE6F0" modified="2018-01-31" version="1">MAITTAQRQTRLDYYYQQIKSIILKRQSPITGLLPASTAVNAHGDYSDAWVRDNVYSILAVWGLGLAYRKIDSDRGRTFELEHSTVKLMRGLMFAMMQQANKVERFKNTQLPLDALHAKYNTQTGNIVVGDDEWGHLQLDATSLFLLMVAQMTASGLHIIFTIDEVNFVQNLVYYIGRAYRTPDYGIWERGNKINRGNAELNASSVGMAKAALEAINGLDLFGLNGSQASVIHVLPDEVARTRITLESLLPRESSSKEVDAALLSIISFPAFAVEDRELVERTRKKIIEKLQGEYGCKRFLRDGHQTVLEDADRLHYEPTELKQFEHIECEWPLFFTYLLLDGIFEGNQSQVQEYEQRLASLAVERSGLSLLPELYYIPAENINAEKSNPRSQQRLPNENVPLVWAQSLYFLGQLLNDGLIAVGDIDPLGKHLSVGRKREPLVQIALLAEDEDLQAELAANGIAAQTPKQVEPIQVRQTKELSAIYTQIGRNDQLGLTGRPVRRLRSLTTSRVFQVRGEAIVFLPSFLDRQEFYLTLDYHFLVSQINSELAYIHRHWSQLGRPTVTLMLTHAMLETGREALFNLMKELRDGHCKNTPVKLGNINQLILTAGTEKIDFLHDFDFTESPVTGAVEVPSYLGYNPEKTWPLGHTQEFKLECETNINLLLISLQKSENLYEQIELLQTLVRLRGINFETGFGTSGESVKVVDLLNEVYTKAGNSSQSKIQWAVIRYAAGLLDKIDISLSDAVTDILVRQKQIAVGKAYSEDSVISRPGSYMEVMEKIRQFCGEDVRDRVLTQEVLIYLGLLIKAEPQLFKGLLTLRVSYFILLLTSELARELGITQNEAYEHLMQLSPFEIKNRLRQVLSEYEEMNQVLKQQESLRVKQSDKEIEWVVAPVSSESQMPVGGWRRKRQMEGAVNRVPKDFYPNVWGMLRHCKGLIIGDKLERRNRLDSDVILSEMTPGEKNFALQVEHLLNKIVAPEYRQVNIEALMELAAIAQRNPELQIEEYIVLDVLIGHAVRLNWLEKNQERADRYDEDKAAAWQAFYNTSPYVCATHVLNAFRFLTQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYT7</accession>
    <name>A0A2G4EYT7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54683">
        <property type="protein sequence ID" value="PHX54683"/>
        <property type="gene ID" value="CP500_014795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="10744" checksum="BDFB76A307F66852" modified="2018-01-31" version="1">MEQASCLFNANNLDAHIVGQASCLFNANNLDAHIVGQASCLFNANNLDAHIVGQASCLFNANNLDAHIVEQASCLFNANNLNAHIVEQASCLFNANNLDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYV0</accession>
    <name>A0A2G4EYV0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_014790</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0187 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54693">
        <property type="protein sequence ID" value="PHX54693"/>
        <property type="gene ID" value="CP500_014790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021134">
        <property type="entry name" value="Bestrophin/UPF0187"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="UPF0187"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="PTHR33281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01062">
        <property type="entry name" value="Bestrophin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="301" mass="34000" checksum="7D8325E5FD4711DF" modified="2018-01-31" version="1">MIDQKRPWFKTALQFRGSVIPLILPRVLVCGGFGVLISLLHFLKLPVSLPILSSIVPSIVLGLLLVFRTNTAYERFWEGRKFWGGVVNNVRNLARQIWVAIDEKDQDDFIAKKSALRLLVAFAVAMKLHLRQESVNSELESLISPSQYEKLKSMNNPPIEVAFWIGDYLNTQYDRNCVDVYQLTAMNQLLNSLIDCLGGCERILRTPIPLAYAIHLKQLLLLYSLALPFQMVKDLSWGTGPVVALISFTLFGIEEIGLEIENPFGHDTNDLPLDNICATMHRNIEDLISLSPSVHSRAEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYZ2</accession>
    <name>A0A2G4EYZ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54732">
        <property type="protein sequence ID" value="PHX54732"/>
        <property type="gene ID" value="CP500_014580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="14231" checksum="06839F8EE4960E81" modified="2018-01-31" version="1">MLKLTYTETGFNLERLAQSPEQLVALRVVLAMRVGQSISVEPSTAAFLLPANLPALALLESEARTDASGTIALCVADAEYVEVTLRGTWISGLSEGADGVFMTVLGDRTEFLVFKLWLETQPVNSVVEEVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ21</accession>
    <name>A0A2G4EZ21_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flavin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_014455</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Mediates electron transfer from NADH to oxygen, reducing it to water. This modular protein has 3 redox cofactors, in other organisms the same activity requires 2 or 3 proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the flavodoxin reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54740">
        <property type="protein sequence ID" value="PHX54740"/>
        <property type="gene ID" value="CP500_014455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="6">
        <location>
            <begin position="269"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="581" mass="63599" checksum="9FCEB0A488036465" modified="2018-01-31" version="1">MTNTLTPKPPSNTKPRDVQFVQIAADTAAVRSRTWDRLKFEVEYSLQKGTTANSYIIQADKTALLDPPGESFTQNYLECLQKRVDLKKLDYVILGHFNANRAVTIKALLELYPQIAFVCTNPAAISLRGAFPEQELNITIVRGEEVLDLGKGHALKFIATPTPRWPDELCTYDPQTRILFTDKFFGSHVCGDQVFDEGWSVYSEDRRYYYDSLHASQAKQVLTAMDKLADLSTAFYAPGHGPIVRYGLHELTNLYREWSQQQNSKDLTVALIYASAYGNTATLAQAIAKGITKAGVAVESINCEFAEPGEIQEAIEKCAGFIIGTPTLAGHAPTQIQTALGIVLSTATKSKLAGVFGSFGWSGEAIDLVEGKLKDAGYRIGFEPIRAKFKPTAATIHECKEAGTDFAQALIRSQKLRAPKPQLAGGSDRTEQAVGRLVGSLCVLSAKRGEVSSAMLASWVSQATFTPPGLTIAVAKDRSIEALMYAGDKFVLNILAEGRQLRKYFMKNFAPGEDRFAGVETMEASNGCPVLSDALAYLECEVMSRMECGDHWVVYAAVENGHLLKNDGVTAVHHRKSGSHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZD5</accession>
    <name>A0A2G4EZD5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="6">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_013635</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54874">
        <property type="protein sequence ID" value="PHX54874"/>
        <property type="gene ID" value="CP500_013635"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05372">
        <property type="entry name" value="ENR_SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="19"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="194"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="258" mass="27571" checksum="330786AA22508E8A" modified="2018-01-31" version="1">MIDLTGKNALVTGIANNRSIAWGIAQQLHKAGANLGITYMKDEKGKHERKVAELVEPLNPSLYLPCNVQNESEIESTFEAIAEKWGKLDILVHCLAFAGKDELSGDFTNTSRQGFSNALDISAYSLIRLCAAAKPLMAEGGSIITLTYLGGVRVIPNYNVMGIAKAALEMNVRYLAAELGPSNIRVNGISSGPIRTLASSAVGGILDMIHHVEEVAPLRRTVTQQEVGNAATFLCSSMASGITGQILYVDAGYEIMGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZG6</accession>
    <name>A0A2G4EZG6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54893">
        <property type="protein sequence ID" value="PHX54893"/>
        <property type="gene ID" value="CP500_013740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9873" checksum="047746E76C46893E" modified="2018-01-31" version="1">MLQDTQTIRHYQKLTDALVEMWNRGYRFDDLRLYLDGYLAALRHSNSLEPYLIHRLEEEAARYIHDTSNFEMPMPQAESGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZH8</accession>
    <name>A0A2G4EZH8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54916">
        <property type="protein sequence ID" value="PHX54916"/>
        <property type="gene ID" value="CP500_013595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="320" mass="35282" checksum="873A90519426728F" modified="2018-01-31" version="1">MTPTKLSDSDKREIIRLYRLSDENTITLAKRYGVSSSTVRRLVQSALSGPEYESLVQQKQKRLSDRTTISQEAEVTVDLSSSSSGSDPLSATVKPSSVANSRPTIRQRFLSVAERVADVEEPGNLNSYLNVSGESAADEMANPGDRSDDVAVTGELKAILPEEGFLLGEDFSDFDEDEDEDDLDDFDGDEDEDEDSLLEGSLLSLRSSGESIGLRAQTLIQVLPLSQASIPKICYLVVDRAAELITRPLKAFGELGQIPSAEIREKTLPVFDNHRVARRFATRHQRVFKIPDGKMLQKTAPYLQAKGITRLLIDGQVYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZM8</accession>
    <name>A0A2G4EZM8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF262 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54962">
        <property type="protein sequence ID" value="PHX54962"/>
        <property type="gene ID" value="CP500_013130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="DUF1524"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="DUF1524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="13"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1524" evidence="2">
        <location>
            <begin position="430"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="695" mass="81220" checksum="F410CBC7681599A1" modified="2018-01-31" version="1">MKADSYKISKVFSSGGGIHYVMPHFQRQYSWETREWKDLLEDAIAIYQEYDSEREPEHFIGSLVVINDGTRNGTIPAFNLVDGQQRLTTLSLLFIVLRDLVKINEPKLSSKISKFLVNSDEEGEGEVYFKLLPTNKYGDRQAYQAIILEETPNQSESGIPKAYDYFYREIESKVKQGELDIGTFFTVLQNCFQVVFIELNKNESPCHIFESLNAKGKPLTQADLVRNYIAMMLPTSQQENAFTKYWEKIEELLQEKRKVGKSGMGELTAFLRHYLAMQTINLCNESHIYERFRDYCKELKDLIFVQELANLLKFADFYNKLLRPEYEVNQDIKTALVRLNTFDLSTAYPFLLTLYNEYNSQQIDFEEFMESLNLLENYLVRRYICGKPTNYLNKMFPSLWKDIIAIKDEDEEITLQEALQKVLITKQYPNNNDVKQLIHRQKLYDPKNTKKISLVIDTINRYLSKGTGGFTVLDQNATIEHILPQAPSEDWDNELGDELKEIHRDYLHTLGNLTLVTSEWNSQLSNSAFLVKKQKLAEHALRINSDYFSQIISRWDEKAILDRTNFLTSKFIEIWPSLGEHQAVLTHTSKPKLMKIYGEEIAYKQSSRQVTILCCEWVIKNRSDSFEKARNLLKSNFQDNMLDRNSDQKRRWHQLSNGCWVGINKSAKDHRKFCRRFLEAVGISEADWSIEYVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZP8</accession>
    <name>A0A2G4EZP8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">xseA</name>
        <name evidence="9" type="ORF">CP500_013245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54982">
        <property type="protein sequence ID" value="PHX54982"/>
        <property type="gene ID" value="CP500_013245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_anti_2" evidence="8">
        <location>
            <begin position="10"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="129"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="276"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="42610" checksum="E7C39D89021F76A1" modified="2018-01-31" version="1">MNSTISEIALSVARLTSYLQDLLEGDRRLQSLWVTGEVASVSEHPSGTYFTLCDADKSAAIRCVVWKSQRQKLIEKPTKGAKLLVMGSLRVYKVRGEYQLTVSQSLPAGEGLQALRLQQLRSRLEAEGLFSPARKRPIPTHPKIVAVVTSDTSAAWGDIQRTLAQRYPGLQVLLSPTGVQGELAPVAIVRAIARVELDGRADLIILGRGGGAAEDLASFNDERVVRAIANCAIPIITGIGHERDESLADLVADRRAHTPTAAAEQAVPNLADIYLQHRQRIIHLANAVRVKFQTEEQHLQLLQNRLKRLPVTSRSLQQASGKLEVLQEKLSALNPAAVLERGYAAVIQSDATIVRTTEGLVLGEELTVKLSRGILKVKIVEILDAEKSYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZQ2</accession>
    <name>A0A2G4EZQ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54994">
        <property type="protein sequence ID" value="PHX54994"/>
        <property type="gene ID" value="CP500_013305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="325" mass="36033" checksum="EBBE2C8176CC87B3" modified="2018-01-31" version="1">MRLEQLQAFLSVAQTGSFQQAAGKCGVTQSTISRQVQGLEAELGLSLFHRMAHAKLTLAGERLLPHARKICQTWQNATQELGDLLAGKQPELCIAAIHSVCAAYLPPVLQKFCRNYPEVQLRVTALGSDRALKVLKDGLVDVAVVMNNRYFTQGPEMLVEVLYNEPIEVLMAASHPLAKYDRVPMAELICYPQVVFKDGYGMQRMVQDEFGRMGAKLQAVLELNTLDAFRGVVRQGELIALLPHSALLEARDDRTLAIRPIDHQRPNSKVSAISSATADPIWTREVVLVTTHDRMQIPPIAHFCQLVREFVPPQFDVLKVGTTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZS1</accession>
    <name>A0A2G4EZS1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54998">
        <property type="protein sequence ID" value="PHX54998"/>
        <property type="gene ID" value="CP500_013175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="217"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="436" mass="48485" checksum="762D1B8E658DF844" modified="2018-01-31" version="1">MVAILGTSAIAIYELFASSLYQELDQRLEVLAQAASHSLVAIEKQHLSEHLEKKGDESDKQSEQRNDYFQIELDREKVTRQLDKDGDLDIPWQNLREPDQSVEWFNEAGKMLGNSGKSLPPVIIKSGFQTIQNGQIRSATIPVYISYNDKKQELKGYIRTSESTKEVEEVLSRLRWNLGYGSIIFLSLTAVGGLWLTKQSLKPIEDSFQQLKQFTADASHELRSPLTAIKTSVEVMQSHPERIHAADVKKMVAIASATKQMTQLVEDLLLLTRMDAPAAMIAREWIAVPLDELLEDLLDLWELQAQEKQIILKSNLAIDTSVMGDPAQLTRLFSNLIGNAIHYTPAGGIVTVSLSRQNRSTIVSVEDTGIGIAPEDVKLVFDRFWRADRARNRRAGGLGMGLAIAQAIVQSHRGEISVTSQLGVGSCFQVKFSSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F011</accession>
    <name>A0A2G4F011_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55102">
        <property type="protein sequence ID" value="PHX55102"/>
        <property type="gene ID" value="CP500_012570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="229" mass="26930" checksum="2735DAAF729CE3BB" modified="2018-01-31" version="1">MNLYFLVEGTQSERKVYPAWLAHLLPELQRVQSCDDVNEKNYYLISGEGYPSLIYDFIPRAIAEINSNGKYSYFVVCLDAEENTVAELTTEIDNFLDEQKLKLNNAELMLIFQNRCLESWLLGNRKIYSRNPQDKPLLDYTKYYDVSVNCPENMGKYQEFNTHAQFHGAYLRSLFEAKNITYSKKRPGDVLKPFYLEQLLARIQVQPEQLTTFRQFIDFCNKIQPKLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F090</accession>
    <name>A0A2G4F090_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55179">
        <property type="protein sequence ID" value="PHX55179"/>
        <property type="gene ID" value="CP500_012410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="SSF101967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="8736" checksum="D2C8526C793BA11B" modified="2018-01-31" version="1">MGIGHWVLGIGHRASGIGHWASGIGHRALGIGHWASGIGHWALVTNENSQPSTVNCQLSTVNSQQSTVNRQPSTVNRQRSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0B5</accession>
    <name>A0A2G4F0B5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55205">
        <property type="protein sequence ID" value="PHX55205"/>
        <property type="gene ID" value="CP500_011945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8194" checksum="843D78EC5679548A" modified="2018-01-31" version="1">MGNWALGIGHWALGMGNWAWGIGHWALGIGHWKLPTANSQLPTHNCLSCCAFKLYISSRNQKSSPPLPPGLFHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0C4</accession>
    <name>A0A2G4F0C4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system HigB family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54897">
        <property type="protein sequence ID" value="PHX54897"/>
        <property type="gene ID" value="CP500_013760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018669">
        <property type="entry name" value="Toxin_HigB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09907">
        <property type="entry name" value="HigB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="12722" checksum="830A869F6AA14561" modified="2018-01-31" version="1">MRLIYQKNLLIAIEPYPDAQTAIESWYQLIKDNDWQSLEEMRKGYSKSVDEVYGYTIFNIKGNRYRLIVQINYRTKIIFFKAFLIHAEYSKINWNNQDKFKQKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0S3</accession>
    <name>A0A2G4F0S3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Photosystem II reaction center protein H</fullName>
            <shortName evidence="7">PSII-H</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">psbH</name>
        <name evidence="8" type="ORF">CP500_011285</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, numerous small proteins, at least 3 peripheral proteins of the oxygen-evolving complex and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cellular thylakoid membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PsbH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55374">
        <property type="protein sequence ID" value="PHX55374"/>
        <property type="gene ID" value="CP500_011285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00752">
        <property type="entry name" value="PSII_PsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001056">
        <property type="entry name" value="PSII_PsbH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036863">
        <property type="entry name" value="PSII_PsbH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34469">
        <property type="entry name" value="PTHR34469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00737">
        <property type="entry name" value="PsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161025">
        <property type="entry name" value="SSF161025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7548" checksum="1D1243D8247D4734" modified="2018-01-31" version="1">MAQRTWLGDILKPLNSEYGKVAPGWGTTLLMSAFIGLFFVFLLIILQIYNSSLILENVDVDWSSLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Z8</accession>
    <name>A0A2G4F0Z8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55425">
        <property type="protein sequence ID" value="PHX55425"/>
        <property type="gene ID" value="CP500_010815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="516" mass="57739" checksum="CF301212CA9133CB" modified="2018-01-31" version="1">MNTTILRGRYHIVKPLSSGGFGETFLAEDWDLPAHPLCVVKRFHPQSNNPFVLQQAARLFKQEAEILHRLGIHDRIPRLFAHIEENQEFYLVEEFIEGEVLSKELIYGTRKGEDDVISLLHDILEVLAFVHGQGVIHRDIKPANLIRRQSDGKIVLIDFGAVKEIGCLSVNMQGQLTPTIAIGTLGYVPDEQANGKPRLSSDVYAVGVIAIQALTGLNPEPNFGGFPEDAVTGEFKWRDAVAVSRQLGSIIDKMVRKDYRQRYTSAVEVLQDLDAFLSSANKPTLVATAPILAPTLAPNLAPTLVPTLPPTQVAKPPVSVRSISGWPRDHRLAAIGILIAIIAVITSLFNSDVRKWFVDLTFGYSYYENKEIKVKYPAEWKPSFYSSGITPDEIVFNSPKDNGFQELVTVSSEKLSNPMSSQEYYTQILQPKIQNQVNHDLLKNPEKTTLGNNPAQMLVFTTPESAGKNPVVLKHKLIWTVKNNQAYIVTYKGEDSNFLDDEQKVIEPMRQSFEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F104</accession>
    <name>A0A2G4F104_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55440">
        <property type="protein sequence ID" value="PHX55440"/>
        <property type="gene ID" value="CP500_010890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="117" mass="13259" checksum="B467E48870A3B11D" modified="2018-01-31" version="1">MILSDTSADKSLPSNSHHHHDRDSVHPHHHDEESMRRLVNRLSRIEGHVRGIKTMVQENRPCPEVLVQVAAVRGALDRVARIILDEHLTQCIARAAKEGNIDTEIEELKAALDRFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1F7</accession>
    <name>A0A2G4F1F7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)H-quinone oxidoreductase subunit K</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NAD(P)H dehydrogenase I subunit K</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit K</fullName>
            <shortName evidence="1">NDH-K</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ndhK</name>
        <name evidence="5" type="ORF">CP500_009965</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cellular thylakoid membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55593">
        <property type="protein sequence ID" value="PHX55593"/>
        <property type="gene ID" value="CP500_009965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="1 2" id="KW-0408">Iron</keyword>
    <keyword evidence="1 2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="1" id="KW-0874">Quinone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="1" id="KW-1278">Translocase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_q6" evidence="4">
        <location>
            <begin position="79"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="241" mass="26768" checksum="F143D0798F0191F8" modified="2018-01-31" version="1">MVLTSDKSQKSLIVNPALRPEVTTELSENVILTTVDDLYNWARLSSLWPLLYGTACCFIEFAALIGSRFDFDRFGLVPRSSPRQADLLITAGTITMKYAPILVRLYEQMPEPKYVIAMGACTITGGMFSVDSPTAVRGVDKLIPVDVYIPGCPPRPEAIIDAIVKLRKKIANDSMQERGNLQPTHRYYTRPHKMKVVDDILDGKYLSIPGRMAPPKELTEAMGMQVPPGLLTAQKQEVNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1J2</accession>
    <name>A0A2G4F1J2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55641">
        <property type="protein sequence ID" value="PHX55641"/>
        <property type="gene ID" value="CP500_009520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="13117" checksum="4E3BF98D50816F33" modified="2018-01-31" version="1">MENKLENYRVYIQQLLEEYANLGTPDPDVDRQTIFDTVHDHYQLVYAGWKNRDRRYGCLFHLDIKDGKIWIQYDGTEIGIADELVKLGVPKEDIVLAFHEPLVRQYTGFAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Q5</accession>
    <name>A0A2G4F1Q5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55691">
        <property type="protein sequence ID" value="PHX55691"/>
        <property type="gene ID" value="CP500_009345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019656">
        <property type="entry name" value="Uncharacterised_Ycf34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10718">
        <property type="entry name" value="Ycf34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9574" checksum="B77E75320A9DB04A" modified="2018-01-31" version="1">MCICINCHYVDRCFTYHAVEGQHEQIHLTETPDFDPVEPTINVNIRPRQDEIEMEWDVVGCQSFKQESGKWAKLRPGELIPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1S6</accession>
    <name>A0A2G4F1S6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Diaminopimelate decarboxylase</fullName>
            <shortName evidence="2">DAP decarboxylase</shortName>
            <shortName evidence="2">DAPDC</shortName>
            <ecNumber evidence="2 3">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">lysA</name>
        <name evidence="6" type="ORF">CP500_009460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="2 3"/>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55711">
        <property type="protein sequence ID" value="PHX55711"/>
        <property type="gene ID" value="CP500_009460"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="5">
        <location>
            <begin position="71"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="4">
        <location>
            <begin position="329"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="322"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="394"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="422"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="472" mass="51297" checksum="AA9C35FADCE629BE" modified="2018-01-31" version="1">MVLTQSIGVESGLQYLSESKESPQSRSPNQELLPLTASVNSRDRLEIGGCEVTALVEQFGSPLYILDEETLRAACSQYRDAFKRYYPGSSQVLYASKAWSCLAVCAIAANEGLGIDVVSSGEIKTALQAGVNPDKIYFHGNNKSREEIQLAVESGCAIVADNWLDLETLAEFGKLGISNPKGTPTRVMVRFTPGIECHTHDYIKTGQIDSKFGFDPNSLKQVFSFLSQQPSLSCVGVHAHIGSQIFELQPHHDLADVIVEAFTEAIRHGLTPTEINIGGGLGIRYTEADDPYSIDDWAKTVCDAMVAACNKQNLPLPKLLCEPGRSLVGTACVTAYTIGSQKVIPGIRTYLSVDGGMSDNPRPITYQSVYRVLAANKMSAPLTETVTVAGKHCESGDILIKDAKLPECQAGDILVVTATGAYNYSMASNYNRVPRPAAVLVRNGEVNTIVQRETDEDLLRFDRLPERLSVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1W8</accession>
    <name>A0A2G4F1W8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_009265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55738">
        <property type="protein sequence ID" value="PHX55738"/>
        <property type="gene ID" value="CP500_009265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012837">
        <property type="entry name" value="NrdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352:SF2">
        <property type="entry name" value="PTHR30352:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00299">
        <property type="entry name" value="anaerobic_ribonucleoside-triph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="22458" checksum="0946EAD3AFC53B44" modified="2018-01-31" version="1">MTLLNIAEICPATRTLGPGKRFVIWVQGCCFNCRHCVSPEWIPQQQATLVEPLQLADYILSVSGTEGLTVSGGEPMLQAAALGVLFAYLREHRDISIMCFTGFTLAQLQGKCDADIDRVLALIDVLIDGQYVAELNDNQGWRGSANQVVHFLSPRHLSEASLFVERKRDVEIHLRDDSALMVGVPPQDFSDSFKRAIDLGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Y2</accession>
    <name>A0A2G4F1Y2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55748">
        <property type="protein sequence ID" value="PHX55748"/>
        <property type="gene ID" value="CP500_009075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="550" mass="60727" checksum="09EDFFF3E4B4B429" modified="2018-01-31" version="1">MLPTFKKLAAIAIFFVAIKVVVDSPYFKKTKDSIAHRNEASATLDPPSLRQTAANKPPAAPTASVDRNFDIVVYGDEVPGICAAIWAKKTLGAKGKVAVVRSNNESAMLGGVLTRGGLGYVDLDKIPDWYRQPYAQCFREFLDKAKVPESCIEPKTADKALKEMLSEADVKVISNSTLTPHVVDRKIEYAQVKGSNVKIKANSFIDVTQDAELARKAGLSYYTGYESQNIKSKNETLAISIVPTITGLTMSDLRRMEDEILYNTPLVEKIKTSITKTNDPASTEFWMRNFLSTIYQAYRDGYNIRSVALGGAYHVDRNLPFTQDKGFFFDKANICVYKDNSMSWNGFLFKYQVDQLMKMEANDRKPTPEMLKEMSYLQEWLQKKSGKDVRVFIPDEAYIRQTLNIRDVVEPLTGKEIIKGGTEAEKSIGSFSYDFDLRGGVKDLSSRIPGLPVYNFGIESALASKVNNLAIVGRSSGYVGMAVSVGRIATVNIYQGQGVGVAAGLASKLGVPLNTITSAKTKQTLETLTGKTTYLSGRDTSYGVDYQEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Y9</accession>
    <name>A0A2G4F1Y9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Polynucleotide phosphorylase</fullName>
            <shortName evidence="6">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pnp</name>
        <name evidence="8" type="ORF">CP500_008975</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55766">
        <property type="protein sequence ID" value="PHX55766"/>
        <property type="gene ID" value="CP500_008975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="633"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="497"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="503"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="717" mass="77587" checksum="4267DBD2DACBE6BD" modified="2018-01-31" version="1">MVEIDKSISFDGRDIRLKIGLLAPQAGGAVLIQSGDTAVLVTATRSQGREGIDFLPLLVDYEERLYAGGKIPGGFLRREGRPPEKVTLTGRLIDRPLRPLFPSWLRDDIQVVATTLSMDEQVPPDVLAVTGASVAILLAKMPFYGPMAAVRVGLVGDDFIINPTYSEIKEGELDLVVAGSPDGVIMVEASANQLPEQDIIEAIDFGYEAACDLIQAQREIMAELGIDLVVGEPPSLDLALENFIRDRAQEPIRIILSRFEKDKTIRNAALDEVKANAVESAIAELAEDDPVKVAATANGKAIGNVFKDVTKQMMRKQILEDGVRVDGRKLDEVRPVSCRVGVLPSRVHGTALFNRGLTQVLSAATLGTPGDAQDLGDDLHPQQDKRYLHHYNFPPFSVGETKPMRSPGRREIGHGALAERALVPVLPSKEDFPYVIRVVSEILSSDGSTSMGSVCASTLALMDAGVPLSQPVSGAAMGLIKEGDEVRILTDIQAIEDFLGDMDFKVAGTDTGITALQMDMKIKGLPLDVIANAIHQAKPARRHILERMLSTIDTPRKEMSPFAPRLLTLKIDPEFIGLVIGPGGKTIKAITEETGVKIDIEDDGTVTIAGNDSEKAMRAHNIIQGMTRKLNAGDVYVGTVTRIIPIGAFVEILPGKEGMIHISQLADYRVGKVEDELAVGDEVIVKVREIDNKGRINLTRLNIHPDEAVAAREALNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F221</accession>
    <name>A0A2G4F221_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55823">
        <property type="protein sequence ID" value="PHX55823"/>
        <property type="gene ID" value="CP500_008690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="8212" checksum="ED6FA5EBA65FE532" modified="2018-01-31" version="1">MIPTSKPKLNTHPWCIVRQLPNMQRLVVARFHRRGDADGYIQILRRLLPATKHAIVFDLTGAEKLPEVRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F263</accession>
    <name>A0A2G4F263_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55832">
        <property type="protein sequence ID" value="PHX55832"/>
        <property type="gene ID" value="CP500_008750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="378" mass="42146" checksum="A0E669C5B9B010E8" modified="2018-01-31" version="1">MFQILVIDDDTAVQELLRRTLKKQGYEVTVASNGEDGIAEAQKLRPALIICDWIMPRLTGIDVCRRVKADPDLSTTQFFLLTSLGSIADRVKGLDAGADDFISKPIELNELQARVRAGLRLHQLSRDLKIAKQSLEAELAEAAEYVQSLLPDPMVEPVSIESKFIPSRQLGGDCFDYNWLDSNYLAIYLLDVAGHGLRAALPSVAVLNLLRSRALPNIDYYKPSDVLRALNTTFQMSYQNDKYFTIWYGVYNRSDRKLVYASAGHPPAVLISQSPSSKAKVQQLRTPGMPVGMFPDARYLDNCCDVEDLSTLYIFSDGVYEINQPDGNIWGLDPFVDLLAAYNGGTADELELVLSYTQKLNAKAVFDDDWSLLKVNFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2E4</accession>
    <name>A0A2G4F2E4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55919">
        <property type="protein sequence ID" value="PHX55919"/>
        <property type="gene ID" value="CP500_008055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7391" checksum="40B663FCAFBAC0DA" modified="2018-01-31" version="1">MGHRAWGIGHLLFFITTVNSQQSTVNSQQLTARSNSQIFPCPILEYILRKKNTLHKNLLATPINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2F2</accession>
    <name>A0A2G4F2F2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit PurL</fullName>
            <shortName evidence="5">FGAM synthase</shortName>
            <ecNumber evidence="5">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Formylglycinamide ribonucleotide amidotransferase subunit II</fullName>
            <shortName evidence="5">FGAR amidotransferase II</shortName>
            <shortName evidence="5">FGAR-AT II</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glutamine amidotransferase PurL</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purL</name>
        <name evidence="10" type="ORF">CP500_009550</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55647">
        <property type="protein sequence ID" value="PHX55647"/>
        <property type="gene ID" value="CP500_009550"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00420">
        <property type="entry name" value="PurL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010074">
        <property type="entry name" value="PRibForGlyAmidine_synth_PurL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43555">
        <property type="entry name" value="PTHR43555"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01736">
        <property type="entry name" value="FGAM_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGAR-AT_linker" evidence="9">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS" evidence="7">
        <location>
            <begin position="89"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="8">
        <location>
            <begin position="204"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS" evidence="7">
        <location>
            <begin position="639"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="8">
        <location>
            <begin position="762"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="95"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="313"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="466"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="587"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="681"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="718"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="719"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="721"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="949" mass="100629" checksum="6E4BD26EC3E177D1" modified="2018-01-31" version="1">MSVISESPFSPAEIASEGIKPEEYEDIVRRLNRHPNKAELGMFGVMWSEHCCYKNSRPLLKQFPTEGDRILVGPGENAGVIDLGNGLQLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPIALLNSLRFGNLDDAKTQRLFKGVVSGISHYGNCIGVPTVGGEVYFDAAYSENPLVNVMALGLMETQEIVKSGASGIGNPVLYVGSTTGRDGMGGASFASAELTDKSMDDRPAVQVGDPFLEKSLIEACLEAFKTGAVVAAQDMGAAGITCSTSEMAAKGGVGIEFDLDKVPVRESGMIPYEYLLSESQERMLFVAEKGREQELIDIFHRWGLQAVVAGTVIEEPIVRILFKGEIAAEITATALADNTPIYHRELLTEPPEYAIKAWEWTADSLPECTVAGIEIDGNLQSWNQILLKLLDTPTIASKRWVYRQYDHQVQNNTVVLPGGADAAVVRLRPVEPCQENPPQPPLGKGGLQEGEPSLGKGGLQEGEPSLGKGGLQEGEPSLGKGGLQEGEPSLGKGGLQEGEPSLGKGGLQEGEPSLGKGGLQEGEPSLGKGGLQEGEPSLGKGGLQEGEPPLGKEGLQEGEERTQASGLQEEAEAIPLFKKTQGRETPELSPPLSKGGPGGVIPGVAATVDCNSRYVYLDPYEGAKAVVAEAARNLSCVGAEPIAVTDNLNFGSPEKPIGYWQLASACRGIAEACRELKTPVTGGNVSLYNETIDSDGNPQPIYPTPVIGMVGLIPDLTKICGQGWQKKGDLIYVLGIGESSQNSELKTSPTLGGSEYLAAIHGIVAGKPPTINFELERKVQAVCRDGIRSGWVCSAHDSAEGGIAIALAESCISGKLGADIHLGFNSANISRWDEILFGEMGNCIVVSVAPENQEIWEAYLEEHLAKMWQKIGQVGGADSPLRVLSADNLGLIEVGMVDMGDRFYNAIERRIGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2U0</accession>
    <name>A0A2G4F2U0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3181 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56081">
        <property type="protein sequence ID" value="PHX56081"/>
        <property type="gene ID" value="CP500_007170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021518">
        <property type="entry name" value="DUF3181"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11378">
        <property type="entry name" value="DUF3181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="100" mass="11277" checksum="20B1411ACF4B8AD4" modified="2018-01-31" version="1">MANTTQAIESLAAEIGENVFIDIAKWHLYLRDAHLHTVVAEQLYSMLEEGNLDADKVEQVLQSIPVKLGGGKREVPLADLIPMQCQVKLMDVLEEFQRKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2V0</accession>
    <name>A0A2G4F2V0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Photosystem II lipoprotein Psb27</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Photosystem II 11 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">psb27</name>
        <name evidence="2" type="ORF">CP500_007480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the repair and/or biogenesis of the calcium-manganese-oxide cluster on the lumenal face of the thylakoid membrane. Its presence in a photosystem II (PSII) preparation prevents binding of some small extrinsic subunits and thus assembly of calcium-manganese-oxide cluster.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Forms a complex with a monomeric, partially assembled PSII. This is probably the complex in which D1 is assembled and/or replaced.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cellular thylakoid membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Lumenal side</orientation>
        </subcellularLocation>
        <text evidence="1">Associated with PSII on the lumenal side of the thylakoid membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Psb27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56065">
        <property type="protein sequence ID" value="PHX56065"/>
        <property type="gene ID" value="CP500_007480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031977">
        <property type="term" value="C:thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010206">
        <property type="term" value="P:photosystem II repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01481">
        <property type="entry name" value="PSII_Psb27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025585">
        <property type="entry name" value="PSII_Pbs27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038450">
        <property type="entry name" value="PSII_Pbs27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017488">
        <property type="entry name" value="PSII_Psb27_cyano_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34041">
        <property type="entry name" value="PTHR34041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13326">
        <property type="entry name" value="PSII_Pbs27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03044">
        <property type="entry name" value="PS_II_psb27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0564">Palmitate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0793">Thylakoid</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="14500" checksum="F7E356A0C67FB180" modified="2018-01-31" version="1">MKHYISRLLALVLVVVIGISGCTNVPATMSGNYREDTLDLVSSLRTALTLPESTPEKAAAQADARTKINDFAAAYRRDPALTKLSSFTTMRTALNSLAGHYSSYPNRPVPEKLKVRLEAEFKQVEMALKRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2W9</accession>
    <name>A0A2G4F2W9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_008960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55807">
        <property type="protein sequence ID" value="PHX55807"/>
        <property type="gene ID" value="CP500_008960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="3">
        <location>
            <begin position="2"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="433" mass="48265" checksum="D9012981E24A0D39" modified="2018-01-31" version="1">MTNSGIPSSAYVHIPFCRRRCYYCDFPVFVVGDRKNGDNSGTIIQYVDVLCQEIRETPNLGQSLKTVFFGGGTPSLLSVSQLNTILETLDSKFGIAAEAEISIEIDPGTFTLEQLLGYVAAGVNRVSLGSQAFQDELLEACGRSHSVADIFESVEIVRSAGIINFSLDLISGLPHQTLAQWQTSLESAIKISPTHLSSYDLVVEPVTAFGRYFQAGEQPLPADETAAQMYRLAREILTNSGYEHYEISNYARPGYQCRHNRVYWENRAYYGFGMGAASYVEGVRLTRPRKTQEYYQWVRSISPINSQPDADLTIIKQDFLMSENEVLLETLMLGFRLAEGLSLSVLADKFGQKTVEKIWQCLQPYWRQGWVEVVDANGTIPYGIASLHAISDEAELLPLSGNLRLSDPEGFLFSNTILATLFDKLEDHIALTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3C4</accession>
    <name>A0A2G4F3C4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAGPA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55977">
        <property type="protein sequence ID" value="PHX55977"/>
        <property type="gene ID" value="CP500_007945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018711">
        <property type="entry name" value="NAGPA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09992">
        <property type="entry name" value="NAGPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAGPA" evidence="2">
        <location>
            <begin position="492"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="673" mass="72630" checksum="8651C85DFCEE62A6" modified="2018-01-31" version="1">MHSRVSISPILAIALCLVWNLAGKAESEKAGLMDATGRQDAHPTTNFKYCGTGILPVAENVATIKGGRQISLNDRIIPLAWTQQPTNSNSANIRTWIADIGLMQSAGVDLLNTADHTKQPVQWFSVSLTETQSLATRSQGQYRYLDVTDFARLSGWQISADGNTLRITSPVANVTGIQQAQREWGDRIVIDLDRPTPWQVNIVDKPSSSPTPAPRDTPDDPTKPSISQPRTPTAPNLETPDDPTKPTVSLQIAPLKPIIGQEWSIAIDAKIAPAIIQRTFQTSKQLLSLKVEPAGTQTKVKVAIPLGWRPQVLSLGNPNRLVIDIRPDSLVEKDILWARGIRWRQQYQNIGTARFPVFSLEVNPRQAGVKIRPLLSNPPTDKGTAPLLETAELSGTAAAINAGFFNRINRLALGAIRRNNKWLSGPILNRGAIAWNDRGEFVINRLTLQETLITPTNQRLSISHLNSAYVQSGIGRYNPDWGTTYTPFSDNEIVVTVAGDQVMGQSPGGAAGKTAFPVPANGYILALRSDLSVATKLTPGTLLRLETNTIPADFNRFPYILGGGPVLVQNSQVVLNAKAEGFSDAYVRQTAIRSAIGRTAPGNLLIVAVHNRAGGAGPNFAELALILQQMGAVEALNLDGGSSTSLYLGGSLLDRPLSTAARVHNAIGIFIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3H9</accession>
    <name>A0A2G4F3H9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56333">
        <property type="protein sequence ID" value="PHX56333"/>
        <property type="gene ID" value="CP500_005990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="32412" checksum="A0E713F17517BD29" modified="2018-01-31" version="1">MSNQLNSNPPHPIISAPIGLLAGFTYPVRAFTLLSQTPKLWGYVLVPVVLNFIIGIGLYLGLLFPSLSGIDILVADLSLRFNTLIANLPAWLSFLAVLTLAFGWLLRILLVAGLLLIIGFLLVQFGVILGSPWYGELSAQLELLRNGQLPQEEPMNLSSIFQDIKRAIAFEFRKLQLLLSFGIPLLLLNFIPGVGSIVGTLGGIALGATLVCFDFLDAPLERRRRPFKEKLEIIRGSLPASGSFGLVCFGLVSIPLLNLLAIPLCVTAGTLFFCDRIWPTYFASQEQTSDTASQIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3I1</accession>
    <name>A0A2G4F3I1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Twitching motility protein PilT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56306">
        <property type="protein sequence ID" value="PHX56306"/>
        <property type="gene ID" value="CP500_006130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09872">
        <property type="entry name" value="PIN_Sll0205-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041705">
        <property type="entry name" value="PIN_Sll0205"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="2"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="14671" checksum="93BBCB754ED81CE3" modified="2018-01-31" version="1">MILLDTHIWVWWVDDNTRLTQKHRDWIQQYQSQGLGVSIISCWEVSKLVEMGRLTLSVTVDEWLKQALAYPGVQLLELTIPIIIESTKLTGFHRDPADQIIVATARICGCPLLTADAKILAYPDVQTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3P9</accession>
    <name>A0A2G4F3P9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56382">
        <property type="protein sequence ID" value="PHX56382"/>
        <property type="gene ID" value="CP500_005560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="32"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="296" mass="32899" checksum="FB875B9EBA5ABA82" modified="2018-01-31" version="1">MSSTQSQFTVHFWGVRGSIASPGAETVRYGGNTPCIEMRVGDSRLIFDGGTGLRVLGQTLLSQMPVEAHMFFTHSHWDHIQGFPFFTPAFVKGNCFNIYGAVAPPPNKATIQQRLNDQMLHPNFPVPLQIMGADLKFNDIKVGDTVEIGDIKVETALLNHPGEALGYRVNWNGYAAAYVTDTEHFPDRLDENVVKLATDAEVLIYDATYTDEEYYSEKSPRVGWGHSTWQEAVKVAQAANVKKLVIFHHDPLHNDEFLDRVGEQVAQRFPNSLMAREGLSLQLLPPQSGVPETSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Q6</accession>
    <name>A0A2G4F3Q6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56365">
        <property type="protein sequence ID" value="PHX56365"/>
        <property type="gene ID" value="CP500_005850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="15"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="627" mass="70053" checksum="7AC83BD25D621576" modified="2018-01-31" version="1">MTNPIYPGITLSNHYRIVRELGQGGFGRTYLAEDAHRFNEPCVLKEFAPQVQGSYALQKSEELFEREAGVLYKLKHNQIPNFRELFRVNISDRGYLFLVQDYIPGQTYRFLLDARKRNGSRFIEAEINQLLIQLLPVLEYTHSLGVIHRDISPDNLILRSSDGMPVLIDFGGVKEVAATAESLFAETNATPAPATRIGKLGYAPAEQMQMGIVCPHSDLYALAATVLVLLTGKEPHQLLDSYTLNWNWRSQCSVSPNLALVLDKMLAHGPGDRYSSAREVLQALSGNPPSVPPSQVTQAPPELQPIAVPPPKLPGIPVSMSNIRSQEKLPAWKMVLLVVAVLSSMGGVGWFAGNYLLNLQSKVQKIPVATGPKRQQEDALHDRFQRLEIDDKFYNGYVSLVDETFYKKYPELGGRLLKEGEDDRNWREKWQKIGDELLDKLENISTNARKRLGSYDASDISRRKAEVNKLNLSSRALNDLADAKFFHLFPEERRDRDILNLAIGQIWQAISSDSLEALQAGASIESIEFENRASSKTLKDNLKPGEGKAYIARLAQNQTLRVNLQAPRKSTLLSIYTPGRTKGARALLEDAEGLSWSGLLDDAGYYEFVVVSKSSEPISYELNLAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3V1</accession>
    <name>A0A2G4F3V1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribulokinase</fullName>
            <ecNumber evidence="3">2.7.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_005315</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-ribulose 5-phosphate = ADP + D-ribulose 1,5-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19365"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoribulokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.19" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56426">
        <property type="protein sequence ID" value="PHX56426"/>
        <property type="gene ID" value="CP500_005315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008974">
        <property type="term" value="F:phosphoribulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006082">
        <property type="entry name" value="PRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00478">
        <property type="entry name" value="PHRIBLKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="4">
        <location>
            <begin position="10"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="334" mass="38254" checksum="7E28AB4D52179964" modified="2018-01-31" version="1">MKSKPDRVVLIGVAGDSGCGKSTFLRRLTDLFGEDFVTVICLDDYHCLDRKQRKQTGITALDPRANNFDLMYEQMKALKEGRGIDKPIYNHETGLLDPPEWVEPNHVIVIEGLHPLYDERVRDLLDFSVYLDISDEVKIAWKIQRDMAERGHRYEDVLFAINARKPDFTAYIDPQKQYADVVLQVLPTNLIKDDKERKVLRVQMIQREGVANFEPAYLFDEGSTINWIPCGRKLTCSYPGIKMYYGPDAFYGHEVSILEVDGQFENLEEVIYIENHLSKTSAKYQGELTHLLLQHREYPGSNNGTGLFQVLVGLKMRATYEKLTAKEAKVAVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3V2</accession>
    <name>A0A2G4F3V2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="9">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_005365</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:49612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.399"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 9">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.95" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56464">
        <property type="protein sequence ID" value="PHX56464"/>
        <property type="gene ID" value="CP500_005365"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006236">
        <property type="entry name" value="PGDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045626">
        <property type="entry name" value="PGDH_ASB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19304">
        <property type="entry name" value="PGDH_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01327">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="455"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="527" mass="56244" checksum="88AE5FEF537171F3" modified="2018-01-31" version="1">MPKVLVSDPIDQAGIDILSQVAQVDVNTGLSAAELVAIIPDYDALMIRSGTQVTKEIIEAGNLLKIIGRAGVGVDNVDVPAATRKGIVVVNSPEGNTIAAAEHAIAMMLSMSRHIPEANASVKSGKWERNRFIGVEVYKKTLGIVGLGKIGSHFAAAAKAMGMKLLAYDPFISAERAEQLGCRLVELELLMRESDYITLHIPKTPETLHLINAEVLSKMKPTARIINCARGGIIDEAALAEAIKSGKIAGAAIDVYEHEPLEADSPLRTVGQNIVLTPHLGASTAEAQVNVAIDVAEQIRDVLLGLPARSAVNIPGIFPDSIEKLKPYLQLAETLGNLVSQLAGGRVDYLNVQLQGELATNQGQPVVVAALKGLLSQALRERVNYVNASIEAKERGIRVVETRDASIRDYTGSLHLRAKGTLGEHTVTGAVLGESEIRITSVDDFPVNVAPTHHMLFTLHRDMPGIIGRIGSQLGSFNVNIASMQVGRKIVRGDAVMVLSLDDPLPEGILAEIIKVPGIRDAYTVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3X2</accession>
    <name>A0A2G4F3X2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pstS</name>
        <name evidence="6" type="ORF">CP500_005185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PstS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56484">
        <property type="protein sequence ID" value="PHX56484"/>
        <property type="gene ID" value="CP500_005185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013565848" description="Phosphate-binding protein" evidence="4">
        <location>
            <begin position="32"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="29"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="342" mass="36092" checksum="53F39161CB9BB82F" modified="2018-01-31" version="1">MFFFTGRWRRAFIVTLAAAAFSLSLISSAVAAVTLNGSGATFPKPLYDRYFSQMRSANQITVNYEGTGSGAGINALIKGTVDFAGSDALMTSAQIAEVKRGVIAVPTAGGAVAVIYNLPGVNNLRLNSDAMKGIFEGKITRWNDAKIAGISGQAKNLPNTAIRVAVRADSSGTTFIFANHLQAIGSTIKGVPQPSWPGSPVSGQGNAGVAGLVRQTAGAIGYVQDTYARQNKLQTAFIQNKAGRFVDANLAEAEKAFAGETFPADFRLVEGNPNDGYPIVGLTWLLVYKEYPAAKADAIKKMVNWVMTTGQGINKQLEYTSIPSATAQKVIQTVNQSVVAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Z5</accession>
    <name>A0A2G4F3Z5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56482">
        <property type="protein sequence ID" value="PHX56482"/>
        <property type="gene ID" value="CP500_005175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="18038" checksum="A103AF00C426F21C" modified="2018-01-31" version="1">MHSDRETGFLPSLGAVTKSYRKNPVSGHFRDRDLRTPTEKPGFYRVLALSRSLIEKTRFLATFAIETYASKPKKPGFYARLCTITKSYRKNPVSGQLCDRDLRIKTKETGFFAKSAGYNEVFKGKTRFLTPGSVPLTCKVLPDCSNSLPYKAGEFKLIIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F464</accession>
    <name>A0A2G4F464_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56536">
        <property type="protein sequence ID" value="PHX56536"/>
        <property type="gene ID" value="CP500_004615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="10616" checksum="954FBBB228215CF5" modified="2018-01-31" version="1">MSISAIDIGTLVVSTPETCGGRPRIAGTRISIAQIAVWNKQGLSVEEILEEIPYLDLAQVYAALSYYHANRNEIEADLAAELAEYQLLESEHRAGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4B1</accession>
    <name>A0A2G4F4B1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56578">
        <property type="protein sequence ID" value="PHX56578"/>
        <property type="gene ID" value="CP500_004855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8810" checksum="41FFEBD4264771F5" modified="2018-01-31" version="1">MALPFLDSPTVSYQLPIANYQTSEGIMTQSVDRIVLPPAFPDRTQLPESDGTFVKNFQEHPQSLILIDFIMRTHFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4B8</accession>
    <name>A0A2G4F4B8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_004705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56585">
        <property type="protein sequence ID" value="PHX56585"/>
        <property type="gene ID" value="CP500_004705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="159"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="199"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="3">
        <location>
            <begin position="513"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="380"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="792" mass="89264" checksum="7C93F0B7A2A1F55F" modified="2018-01-31" version="1">MKRIIISVLALGVCLTPLTVPLMVQPNWGQSRDSHIEQLRQLIQQAIQQQQQGKPREAIETWQQVLAIARQFKYRELEARVLNAIGCNYHSLSQPQEALKYYNQALPILRSVGDYREEATTLSNIGQVYDSISQPQEALKYYNQALPIMREVKDRSGEAATLSNIGLVYNSISQPQEALKYYNQALPIRREVGDRSGEAVTLNNIGLVYDSISQPQEALKYYNQALQITREVGNRSGEAATLSNIGGVYNSISQPQEALKYLNQALPIRREVGDRSGEAVTLSNIGMVYRDTKQPTQAIENLQQSVNITLEIRSGLQQENRQKFLEAERGPAKALTSFLIDQNQADRAFQWVNIATTADLADYTRLINAKVANPQAQTAINEWNQKNQQLQYLRRQLQDKFSENLSRQMWELETEVNRKAEEIRRQFPEVAELFETTPKDIAQLKASIAPDTVVIQPVLLTNVKNVPNTVALFVLTKDSLSVKKIAIDPAEFDKLLTEHREEISNYLTSDYRKTGDKLYDILIRPVEDKIQALSPKQLSIIATGKLRYIPFETLWDTKNRKFLIQKYPVNYLTRISTRSIPNSTLQGGVLALGNPVTRNPYNLPDSPQEVQSLTQIFPGSLSYIGNAATLDQFKTQAPRFPFLHLATHGCFQPEGCCLLNSPNCRKPDRVDLKPNTILFADDHELDIADAALLGLQNTRLLTLSACQTAMQSNSNGEEISGVAYVFERAGARAVMASLWSVSDSATKDLMVQFYQNINKGMSKNEALRQAKLSQIGRHPFYWSPFILIGDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4D1</accession>
    <name>A0A2G4F4D1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56622">
        <property type="protein sequence ID" value="PHX56622"/>
        <property type="gene ID" value="CP500_004580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="10"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="185" mass="20794" checksum="B5BCC7D324887A09" modified="2018-01-31" version="1">MSLQRETMGTLINSYAPDFELPGIDEEVHHLARYLEKFRAIGVIFMCNHCPYVKLYLNRLKEIQAEFQDQAVTLIGINANDANQYPDDSFENMKTFAANNQLNFPYIRDVAQDVAESFGASKTPEVFLLDQDGKLRYKGLIDDNADDAGAVQVSYLRSAIGQLLSDESVEPSSTDAIGCSIKWRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4G9</accession>
    <name>A0A2G4F4G9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7-cyano-7-deazaguanine synthase</fullName>
            <ecNumber evidence="1">6.3.4.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">7-cyano-7-carbaguanine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">PreQ(0) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Queuosine biosynthesis protein QueC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">queC</name>
        <name evidence="2" type="ORF">CP500_004305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-carboxy-7-deazaguanine + ATP + NH4(+) = 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27982"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the QueC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.20" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56638">
        <property type="protein sequence ID" value="PHX56638"/>
        <property type="gene ID" value="CP500_004305"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01995">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01633">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018317">
        <property type="entry name" value="QueC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42914">
        <property type="entry name" value="PTHR42914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06508">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006293">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00364">
        <property type="entry name" value="TIGR00364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="224" mass="24796" checksum="77D7EF9614A22974" modified="2018-01-31" version="1">MKAVILLSGGLDSSTVLYQAKADGCECYSISFDYQQRHRRELESARAIALSAHVKAHQIVNFDLTLWGGSALTDNEIDLPIDRTLTEMSQNIPITYVPARNTIFLSFALAYAETLGAQRIYIGVNALDYSGYPDCRLDYIQAMQEVFRLGTKQGREGDAINIVTPLIELKKTEIIQLGNKLGVPWEQTWSCYAGGENACGVCDSCRLRLAAFEELGLQDPVSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4P4</accession>
    <name>A0A2G4F4P4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56763">
        <property type="protein sequence ID" value="PHX56763"/>
        <property type="gene ID" value="CP500_003915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="16477" checksum="CE53E3165C33D3BB" modified="2018-01-31" version="1">MIQESPRVHAGECQQKVDEKQFQLLIGFTTQLSDPMKQAKFDQQIREGTAAKEFSKGLSGNKELQFTNPATLTLQDNTGEVSAGWRSQGKIQNIPMNVDYAIFRRGKIGAFTAIIYLDGANPTVTISDAARKLDSRMMELKPDLTKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Z9</accession>
    <name>A0A2G4F4Z9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Electron transfer protein with DM13 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56864">
        <property type="protein sequence ID" value="PHX56864"/>
        <property type="gene ID" value="CP500_003040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019545">
        <property type="entry name" value="DM13_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10517">
        <property type="entry name" value="DM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51549">
        <property type="entry name" value="DM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013814563" evidence="2">
        <location>
            <begin position="26"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="DM13" evidence="3">
        <location>
            <begin position="68"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="19593" checksum="A46BF931C5448B07" modified="2018-01-31" version="1">MKRRYFNFASFTFVLTIAIACTKTAGDRTATASSGTSETTPTPAAVSSPTGPATSPVTAQAAKVLASGTFVDGEHPTKGTARIVQKGNQRILELDRAFKTSTSGPDLVVILHKSPDVIGSTVPPAYPIKKGDYVFIAPLKSYSGAQSYVIPASINSEDFASAAIWCRKFNATFGAARLQRSSSARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F578</accession>
    <name>A0A2G4F578_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56885">
        <property type="protein sequence ID" value="PHX56885"/>
        <property type="gene ID" value="CP500_003165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7098" checksum="C74EBCD00C666811" modified="2018-01-31" version="1">MSIRLICCTIVSNRQDACSTKNEFSCGVGILPACERLIDIGARSELNLDHISCGTGILPVQDWLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5B8</accession>
    <name>A0A2G4F5B8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA/RhaT family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56925">
        <property type="protein sequence ID" value="PHX56925"/>
        <property type="gene ID" value="CP500_002805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="8"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="158"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="298" mass="32242" checksum="EF18D4F808D72FCE" modified="2018-01-31" version="1">MSTENKSFLLGSLGVLIFALTLPMTRLATGSAIEPALSPWFVSFGRAALAGLLSIIYLVAVQAPRPKREDYLPLTLAATGNVLGWPIFLALGLRYVESTHASVITGILPLATAIMGALIFRRKPSAGFWLFSIAGTVLVVAFAWLRGAGVSVAGVSVHWADFLLLLAVLCAAFGYAVGARLSQRWPGEIVICWMLILLLPITIPVTLIAWPTAPIPLPSWGGFFYVSLLSMWLGMFVWYRALAMGDVVRVSQLQLIQPFLSIIFSVPLLGESLDAMTLIFGLAVIVTVFFAKRMPIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5C7</accession>
    <name>A0A2G4F5C7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56938">
        <property type="protein sequence ID" value="PHX56938"/>
        <property type="gene ID" value="CP500_002875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013572614" evidence="1">
        <location>
            <begin position="41"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="387" mass="42921" checksum="82E55012F2AE4477" modified="2018-01-31" version="1">MMKFGYSVFQRLTTKRMLRNICLWAIVAFLASSVISVATAAERKQENKSQPYAIGLWGDLPYSDVQALTGVPNLIADMNSQNLVFTVHDGDLKAGSGTPGSVTPTTCSEDFYKQSLGFFNALKAPAAFTPGDNDWTDCDRPANGGFSSRERLDRERQLFFNTKFTLGQRKLAQTVQRAPLCLGVNGAVPCVENRRWAVGNVTYVTLNVPGSCNNLCDTAPDSAEYNARNQSNIVWLRESFKAAKDSNSVAVMIITQANPGWDLTDGTRAPLRDPNTLVETDKQADGTLTPDGYKDFLIALRDETIAFRKPVAYVHGDSHYYRVDKPFLDSQGQRLENFTRVETFGDNVANGINDVQWLKVTVNPRDREVFSYQPQIVPKNRVAVPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5I4</accession>
    <name>A0A2G4F5I4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HNHc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56985">
        <property type="protein sequence ID" value="PHX56985"/>
        <property type="gene ID" value="CP500_002550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HNHc" evidence="3">
        <location>
            <begin position="322"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="430" mass="48519" checksum="8A7D08F2D8081CB1" modified="2018-01-31" version="1">MSREEAVRRIEQAAEEKLTKLDLSELGLKELPLEIVKCTHLTHLNLYNNQITSIPEVLGQLSNLELLYIHWNHITYIPEALGQLSKLRYLNLEGNRIIYIPEALGQLSSLVFLFLSVNQITSIPKAIGQLSSLEMLSLHTNKITSIPEALGQLSNLDSLHLTGNQIREIPEVIGQLSSLEVLSLDDNYITTIPEVIGQLSNLELLFLRNNQITEIPEVIRRMKNLKSLDLRGNPVPIPPQVLGYNQDFEGYGDLQTILDSYFRTRNPALPELDAERQKIESEGHFDAENLQDARRRIIVSIVQRQGQAEFRRKLLIAYGGRCPITDCDVESAIEAAHIIPYQGTQTNHPTNGLPLRADIHTLFDLHLLSIRPDTNEVVIAPELVGTCYEDLADRKLTLPQDQKTAPNQNALSKHYEAFLSKCKSGQLKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5K2</accession>
    <name>A0A2G4F5K2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57064">
        <property type="protein sequence ID" value="PHX57064"/>
        <property type="gene ID" value="CP500_001940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044719">
        <property type="entry name" value="TIC62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47285">
        <property type="entry name" value="PTHR47285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="219" mass="23628" checksum="D5F91DAA08CE55D1" modified="2018-01-31" version="1">MKAFVAGATGQTGRRIVTELVKRGIPVRALVRNLETARQILPPEAELVTGDVLNATSLGDAIGDSTVLLCATGAAPGFDPTLPYRVDFEGTKNLVDAAKAKGIEHFVLVTSLCVSNFFHPLNLFWLILVWKKQAEDYLQKSGLTYTIVRPGGLKNEDNSNAIVMESADKLSDGSIPRTKVAEVCVAALFEPASRNKLVEIVAKSEAPEKSFEQLFASVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5N4</accession>
    <name>A0A2G4F5N4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_003390</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56787">
        <property type="protein sequence ID" value="PHX56787"/>
        <property type="gene ID" value="CP500_003390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="34"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="354"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="396"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="438"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="480"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="560"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="589"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="631"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="667" mass="72812" checksum="12C8DDB65D54C1A9" modified="2018-01-31" version="1">MSYCLNPACQNPQNADRTQFCLNCGAKLLLRERYRALKPLGRGGFGRTFLAVDEDKPSKPRCAIKQFFPLSQGTSSAEKAAELFNREAVRLDELGKHPQIPELLAHFQQERYQYLVQEFIEGQNLQQELARTGPYNENQIRSLLNDLLPVLEFVHSRSVIHRDIKPPNIIRRRLSESSIIYTYPTLTGELVLVDFGAAKVVEPSIDIGTVIGSPEFVAPEQIRGQAVYASDLYSLGVTCIYLLTQVSPFDLFDINQDTWVWRDFLKVQFDPKLGRILDKMIEASLSRRYKSVAEVLQDLPPQQRAGTGAPPLQRPVIPVQNSLPPTVAGTIIPVPQVLRVVPAHAPTWRCVHTLVGHSNAVTSVAFSPDGKTLASGSEDKTIEMWKLDAGKRWYTLTGHSDWVTCVAFSPDGRTLASSGRDKTIHIWDLNKGKWWYALTGHSDRVSAVAFSPNGQVLASSSRDKTVRLWNLNKGRWMSTLIGHAEGVEAVAFSPDGEFLASGSRDKTLQLWDWQAGKSLCTLADHGDWVRSQVFGPISAVLPTGLTPPNPPLVRGGVGGGSILVSGSRDGTAKLWRVDAEGQGTLLRSFRDNSGDVLCVALGPDGKVLASGSKDGTIYLWDAEGGGLLEILSGHGGEVLSVAFSADGGSLASGGGDRTVKIWRAIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5P9</accession>
    <name>A0A2G4F5P9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57090">
        <property type="protein sequence ID" value="PHX57090"/>
        <property type="gene ID" value="CP500_002080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="88"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="129"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="170"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="211"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="252"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="293"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="334"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="375"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="416"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="457"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="498"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="539"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="580"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="635"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="683" mass="74632" checksum="2451018E2D278C35" modified="2018-01-31" version="1">MTQNQPTKLETDQPVKLKSMEIEKAGHHALELFKSDRNQIEALRVAIGAAESLQKWTLNNPSVATYPSTSPLLALQVILSKIRDRHQFVGHRSTVRSICFSPNQDAIATASIDGSAQLWNLQGKCLATFSGHKDWVNSVSFSQKQNAIATASDDKTAKLWDLQGNCLTTFTGHNDWVTSVRLSPTVAALVTASYDRTAKLWDFQGNCLVTFSGHQQSVTSVCLSPKGDTLATASYDGTAKLWDFRGNCLVTFSGHDGWVTSLSFSPTGNAIATASYDGTAKLWDLEGNCLVTFTGHNSWITSLSFSPTGDAIATASNDRTAKIWDLQGNCLVTFSGHDSWITSLSFSPNGDALATASNDRTARLWHLQGNNLVTCSGHQKSVNSVSCSPYQDRIATASNDRTAKLWNFQGKCLVTLTGHTDWVTSVSCSPNQPRIATTSRDETAKLWNFQGKCLTTFIGHLDSVWSVCFSPKGDTIATASRDATTKLWNLRGKCLMTFTGHQNWVTSVNFSPKGDTIATASRDDTAKLWNFQGKCLATLIGHLDSVWSVCFNPHRDVLATASNDGTAKLWDLYGNCLVTFTGHDGPVLSVCFSPMGDTLATASIDRSIKLWDLRGNLLAEYRGYQGNLSLGEANFVDLKTPIYSVCFSRDGKFLIAGSEDGMVRFWPVESLDELLVRARKWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Y3</accession>
    <name>A0A2G4F5Y3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56897">
        <property type="protein sequence ID" value="PHX56897"/>
        <property type="gene ID" value="CP500_002655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="21888" checksum="B262CAE866D1FF3B" modified="2018-01-31" version="1">MIELSTEQLLYLLYAVAYSKQSKATKGDVKQHLSKGYQKDANAICDILCQKQLLESPKKGQLFVTEQGKKVLATNLQTSKYEFDSAKGAKLINTLWRYCQVGVADSQTSDGGKEMDFEKFVEKFKALYFEERKRQELRGVVAIRSREICHKFLEQNDISQSNLNKNFALLKSTGKVFAVIEKEDELIQWVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F623</accession>
    <name>A0A2G4F623_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57222">
        <property type="protein sequence ID" value="PHX57222"/>
        <property type="gene ID" value="CP500_001375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="265" mass="29880" checksum="A5D884777CC49535" modified="2018-01-31" version="1">MPLCDTLLRAAETELYIVHFSQEILDGATRNLVKNGKMTDAKAARFQTMIKNTFPEAMVEVPPSLVEAMTNHHGDRHVVAAAIIANAKIIVTDNLKHFPTEALEPYGIEVQHPDVFLNQLFDNDPESIVEVIRQQAEDLKKPPITVAELIDNLEKNNRVPEFVSRVRLYEYCDLVIDTAKQALTVLGTPVVEGGRSYEGDRYRLWMKGQTLTITAKDSRGEILRVQNMEIEGNISSEDVTLFQIFAKCLEQELATIRTRVSNKLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F673</accession>
    <name>A0A2G4F673_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57225">
        <property type="protein sequence ID" value="PHX57225"/>
        <property type="gene ID" value="CP500_000840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="439" mass="49366" checksum="2935BAC5363D522E" modified="2018-01-31" version="1">MIRKIKPIALEIFTRYNQIASPKKSGLIAIILSVCLLIFAGCQSAINKNDGVIHLTLWQGINPPVNRDVFQKLVAEFNQKNHDIQVESIFVGQQLPKILTSVVGNSPPDILYFYPQVTGQFVNLDAIVPLEDWLDKLPLKSELYPQVLDEVKLNGHTWSVPMSTSPIGIFYRPKLFKEAGITELPKTWKELREVAKKLTIDSNADGKPEQYGMLIPFGKGEWTVFTWFPFLLSANGEIVQNNRPNLMNPGAIRAVQFWQDLLKDGSATLSMPERGYEEGDFISGRVAMQITGPWTYIMKSNVDYGVFPVPVDVRPATVVGTGTLFVMKTTPERQKAALKFLEYVLSKEFQTKWSIGTGFLPINMKSAKSQAYQEFLKQKPVLNVFIEQLSVAGSRPIIAGYSRISENLGRAIEASMLGQPVEKSLQEAQDRLELIWEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F674</accession>
    <name>A0A2G4F674_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="8">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="8">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">ImGP synthase subunit HisH</fullName>
            <shortName evidence="8">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisH</name>
        <name evidence="11" type="ORF">CP500_001035</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="8"/>
    <dbReference type="EC" id="3.5.1.2" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57256">
        <property type="protein sequence ID" value="PHX57256"/>
        <property type="gene ID" value="CP500_001035"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="6"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX57256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="210" mass="22735" checksum="42FAA332F76AFACE" modified="2018-01-31" version="1">MSVIAVVDYDMGNLHSVCKGLENVGAVPKITDSPAIIEQADAVVLPGVGSFDPAMQNLRSRNLIEPIKNAIASGKPFLGICLGLQILFESSEEGVEPGLGVIPGTVRRFRSEPGLTIPHMGWNQLQFAQDLALWQNLPAEPWVYFVHSYYVDPVDPKVRSAIVTHGSQNVTAAIAKDNLMAVQFHPEKSSSTGLQMLSNFVMQVRGKVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F680</accession>
    <name>A0A2G4F680_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57258">
        <property type="protein sequence ID" value="PHX57258"/>
        <property type="gene ID" value="CP500_001045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="11"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="17542" checksum="592ACA6C165EB632" modified="2018-01-31" version="1">MLDEQAKKTILRKIPHGLYICGVKDGEEVNGFTASWVMQSSFTPPLVVNCVKQDSKSHAMIKASGVFALSFLEAGQKELAMKFFKQQRRVGNKFEDVEFYTGPETGCPIISDTLGYVECRVVGAVEHGDHTVYVGEVVGAGIHREGEPLLLESTGWNYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F685</accession>
    <name>A0A2G4F685_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dienelactone hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57259">
        <property type="protein sequence ID" value="PHX57259"/>
        <property type="gene ID" value="CP500_001050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013841478" evidence="1">
        <location>
            <begin position="23"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="DLH" evidence="2">
        <location>
            <begin position="52"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="278" mass="30314" checksum="CC0CA19E0E30A21E" modified="2018-01-31" version="1">MKDLTRRQFIAVTALTAGFALAVHPIAAATITTDTNGLVAGEVKIPVKDGEIPAYRAMPANGSNFPVVLVIQEIFGVHAHIQDICRRFAKLGYLAIAPEMFARQGDVSKITDIQEIISKVVSQVPDAQVMSDLDATVDWVQKSGKGNINQLGITGFCWGGRIVWLYAAHNPKVKAGVAWYGRLVGDSTALTPKGAIDLAPTFKVPVLGLYGGKDELIPNDTVEKMQQVLKTGSSGSEIILYPDTPHGFNADYRPTYREKEANDAWKRLQDWFKKYGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6A3</accession>
    <name>A0A2G4F6A3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57323">
        <property type="protein sequence ID" value="PHX57323"/>
        <property type="gene ID" value="CP500_000650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="20579" checksum="5CF92D58E336181C" modified="2018-01-31" version="1">MNTVVKPHWKTLDRFVEINSDWVKLIGEHLETSEGKTLEYWRVERADSVVILTIQADKFLFPARMYRPGVGEATLDFPGGRVPPGATAAAAVPAIIKRELGVPESAIAQIRPLNAIGWAINSSFSNQKLYGFVAELHSEITVNPEFIGATYSVSPAGIRELLKKLTCLQCRALLLEWQSQSINFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6G6</accession>
    <name>A0A2G4F6G6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">RuBisCO accumulation factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">raf1</name>
        <name evidence="10" type="ORF">CP500_000105</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">A major RuBisCO chaperone. Acts after GroEL-GroES chaperonin to fold and/or assemble the large subunit of RuBisCO (ccbL, rbcL). Cooperates with RbcX in RbcL folding, plays the major role in assembly of dimers into RbcL(8)-Raf1(8) intermediate complexes. RbcS replaces Raf1, leading to holoenzyme formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Forms an RbcL(8)-Raf1(8) complex. Forms complexes of many stoichiometries with RbcL with and without RbcS. RbcX and Raf1 can bind simultaneously to RbcL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Has 3 domains, the N-terminal alpha-helical domain, an extended flexible linker and the C-terminal beta-sheet domain. The 2 C-terminal beta-sheet domains are swapped and pack against each other to form the dimer interface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57383">
        <property type="protein sequence ID" value="PHX57383"/>
        <property type="gene ID" value="CP500_000105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110102">
        <property type="term" value="P:ribulose bisphosphate carboxylase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00856">
        <property type="entry name" value="Raf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037494">
        <property type="entry name" value="RAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040858">
        <property type="entry name" value="Raf1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046382">
        <property type="entry name" value="Raf1_cyn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040781">
        <property type="entry name" value="Raf1_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041358">
        <property type="entry name" value="Raf1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35299">
        <property type="entry name" value="PTHR35299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18579">
        <property type="entry name" value="Raf1_HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18578">
        <property type="entry name" value="Raf1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18087">
        <property type="entry name" value="RuBisCo_chap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="3 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Raf1_HTH" evidence="9">
        <location>
            <begin position="23"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Raf1_N" evidence="8">
        <location>
            <begin position="93"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="RuBisCo_chap_C" evidence="7">
        <location>
            <begin position="212"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal beta-sheet" evidence="6">
        <location>
            <begin position="224"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="364" mass="40456" checksum="9293589DF7574B9F" modified="2018-01-31" version="1">MTDTPQDSSGPASLSSTDAVELENLVRSLRRKEGGWVHWGQACTALQKAGYSTQRIFEETGFEPIQQNQVSVAAQVYTSMVTAGTSEEVRSHFLAKGSDILYEFRVLSQPQRAAAAALILAHNLDVDDARDVAKAMKEFSRIGSLPQGFTDTAGDAMAYQCWQSARQNSDLQERSRLIARGLKLASSPSARQQIEHLLVDFTVVTRRSAPRLPVYRLDSEEQLPRIVPVVGELPLSTADLQAVPLLEEIEPFRMVKFSGSGAWVAIPGWQVILNAEDPVAVLEMSDRLPVPLQGKVEEVLIIADRAQREWDGDSYFLADNGGNLELYWFEESPDIPILGRVVLVMRPKKILDEDYTKDGWQIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6J8</accession>
    <name>A0A2G4F6J8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF445 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_000090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0754 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57380">
        <property type="protein sequence ID" value="PHX57380"/>
        <property type="gene ID" value="CP500_000090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007383">
        <property type="entry name" value="DUF445"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016991">
        <property type="entry name" value="UCP032178"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04286">
        <property type="entry name" value="DUF445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032178">
        <property type="entry name" value="UCP032178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="410" mass="46483" checksum="9AD21FDE4D1FA26C" modified="2018-01-31" version="1">MNPSDIWLFFAPPVVGGIIGYFTNDIAIKMLFRPYRAIYVKGRKLPFTPGLIPRNQERLAKRISDTIMGSLLTPEELQKLARRLLQTERMQSVILWLLQLALDQVKADAEQKTAKILANILRDLLGESVPRILKVLARREDFLEAQLNQIFDQILLEIQLTEAQAGQLADWLLQIVIPPEVLRQALIDFLTDRNISIIDEGFREKTSGTYWVVANLFGLRNTLTRLRTFCLDDRQATNQRLAELTVSLGVRGRIQEWLQNLSMQNLPVSTVRQLRKTMRDSVRSYVQERGMEVLQGLSKSIDWENISKLILNRLQTSAVMSASLEMVSQELALVLERYLERDLENIVAQAIPILNIDQVIVDRVKGTSPEDLELGIQGIVKSELQGIVNLGGLLGVLVGCLQTVVLVLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6R1</accession>
    <name>A0A2G4F6R1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF29 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57446">
        <property type="protein sequence ID" value="PHX57446"/>
        <property type="gene ID" value="CP500_000480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002636">
        <property type="entry name" value="DUF29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34235">
        <property type="entry name" value="PTHR34235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01724">
        <property type="entry name" value="DUF29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="19844" checksum="919C4A600A719BFF" modified="2018-01-31" version="1">MTQELIDLRTSILEGRYTDALAIVDELDGMSKQAILRQIQSFLNVLLIHLIKNQVEQRLTGSWANSIRNSIKEIKKANIKDNKASYYINSDEWQNFIEEEVIEDAIAEAAEEVFNGAYSQFKLAEMMDRNLIIQTAVRLLNLTYIHSAKDLPAVLAEYLSQLPGGEDWINRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6V3</accession>
    <name>A0A2G4F6V3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57287">
        <property type="protein sequence ID" value="PHX57287"/>
        <property type="gene ID" value="CP500_001210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="178" mass="19923" checksum="74AF3C9AFE683034" modified="2018-01-31" version="1">MIESIAKLSLTDFLAQPDIESSPAWELILGRAVQKTMPTLFHSRLQHNLVNYINDRTDRFEAIPELRCLVLPYSPVPDIAIVAGDRLTDEDGPLNGAPDWLIEIRSPDQSTLNLQNKILHCLSNGTKLAWLIDISHQQVWVWQGEDLPIICSGADILPVLGIPPELTVDAVMAMIRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUD3</accession>
    <name>A0A2G4EUD3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_023060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000262">
        <property type="protein sequence ID" value="PHX53149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53149">
        <property type="protein sequence ID" value="PHX53149"/>
        <property type="gene ID" value="CP500_023060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8395" checksum="D36A836C1FA5D5B5" modified="2018-01-31" version="1">MARHRIKGSDLAERLKISTNAISRLKNAKTMPRIDGDRLNNLCNALNKLAENAENWNAEITPTMLIEYVRDENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUJ3</accession>
    <name>A0A2G4EUJ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_022740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000244">
        <property type="protein sequence ID" value="PHX53201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53201">
        <property type="protein sequence ID" value="PHX53201"/>
        <property type="gene ID" value="CP500_022740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="4">
        <location>
            <begin position="4"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="3">
        <location>
            <begin position="353"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="192"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="492" mass="53868" checksum="770B2925F3A8E139" modified="2018-01-31" version="1">MIDYDLVIIGGTTAGRYAALTATGFQARVALVEPFSNSQDLPNLGQEAIALSSQYNQILNESSRFAEQISSQKFGVHWATTNSEMPIELRFDGVMKWAEGVVANLSEINSLGVLATRGVDVICGDGEFVLKPDLAFAVNGRKLRSLSYLLACPSLPAIPNIEGLSSVGYFTSETVWQLAKQQQLPKSLVVIGADPSGVEVAQTFARLGVAVTVVVKGSHILAKEEREAASLVQAAMEAQGVRILTATEVTQARVIDGKKWIQAGDLAIETEEILIAAGHQPNFKSLNLEGTGVKFNHQGLIVNDKLQTTNSQIYACGDVAGGYPFPHIANSEALVAVKNALFLPMFKIDYRGIPWAIFSEPQLARVGLNEAQARRRFSDDVIVSREYFKNIEKAQICGDLTGFCKIVARRNGEILGASIVGPQAGELIHVIALALRQGMKVDAIAELPFICSTFSDINGKTAAIWELQRFHSNTFMRNLWENLFHWRRYWKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUQ4</accession>
    <name>A0A2G4EUQ4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">infC</name>
        <name evidence="8" type="ORF">CP500_022670</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the IF-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000239">
        <property type="protein sequence ID" value="PHX53218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53218">
        <property type="protein sequence ID" value="PHX53218"/>
        <property type="gene ID" value="CP500_022670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00080">
        <property type="entry name" value="IF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019813">
        <property type="entry name" value="Translation_initiation_fac3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00938">
        <property type="entry name" value="IF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="7">
        <location>
            <begin position="15"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="6">
        <location>
            <begin position="92"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="178" mass="20790" checksum="A5E7C601C6A5FFD3" modified="2018-01-31" version="1">MPVIERRQNRNLPQINENIRYPKIRVIDTDGAQLGILTPSEALRLAEEKELDLVLVSDKADPPVCRVMDYGKYKFEQEKKAREAKRKQHTADVKEVKMRYKIEEHDYQVRLKLADRFIKSGDKVKATIMFRGREIQHSNLAEDLLKRMATDLQEIAEVQQSPKKEGRSMMMLLSPKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV93</accession>
    <name>A0A2G4EV93_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Formate acetyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.54</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Pyruvate formate-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_021455</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + formate = CoA + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:11844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Fermentation; pyruvate fermentation; formate from pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.54" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000196">
        <property type="protein sequence ID" value="PHX53451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53451">
        <property type="protein sequence ID" value="PHX53451"/>
        <property type="gene ID" value="CP500_021455"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00920">
        <property type="reaction ID" value="UER00891"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008861">
        <property type="term" value="F:formate C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01678">
        <property type="entry name" value="PFL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005949">
        <property type="entry name" value="Form_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01255">
        <property type="entry name" value="pyr_form_ly_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="5 7 8" id="KW-0556">Organic radical</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFL" evidence="10">
        <location>
            <begin position="1"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="9">
        <location>
            <begin position="619"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="7">
        <location>
            <position position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="742" mass="83837" checksum="F19578A8B88D673A" modified="2018-01-31" version="1">MYAEWHGFTGGSWTKEVNVRDFIQKNYTPYEGNAEFLVGATTRTQKLWQEVLELMKLELQKGVLDVDTKVPSSIIAHDAGYIHRELEQIVGLQTDQPLKRAIMPYGGIRVVKAGLEAYGYQLDPQTEEVFTKYRKTHNDGVFDVYTREMRMARRSGIITGLPDAYGRGRIIGDYRRVALYGVDRLIDDKKAQQESLELDMMDEETIRLREELSEQVRALFELKEMGAKYGFDIGRPAGNSQEAVQWLYFGYLGAVKEQNGAAMSLGRVSTFLDVYFERDLRSGSRSEVELQELIDHFVMKLRMVRFLRTPDYNALFSGDPTWVTEAIGGMSADGRTMVTKSSYRFLHTLSNLGPAPEPNLTVLWSEHLPENFKEFCAKISSDTSSIQYENDDLMRPTYGDDYAIACCVSVMRIGKQMQFFGARVNLAKTLLYAINGGKDEKSGDQIAPLFAPITAEYLDYQEVNERLQQMMAWLAKAYINTLNVIHYMHDKYCYERIEMALHDRDVYRTMACGIAGLSVVADSLSAIKYAKVKVERNEQGLAVDYLIEGDYPQYGNNDDRVDSMAIDIVQRFMNEIRKHKTYRGAVPTQSVLTITSNVVYGKKTGSTPDGRKAGEPFAPGANPMHGRDSCGAIASLSSVAKLPYSDCQDGISNTFSILPAALGRLESDRTNNLVGLLDGYFHDGGHHINVNAIDRTTLLDAMEHPENYPQLTIRVSGYAVNFIKLTREQQLDVIKRTFHERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVC5</accession>
    <name>A0A2G4EVC5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000201">
        <property type="protein sequence ID" value="PHX53416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53416">
        <property type="protein sequence ID" value="PHX53416"/>
        <property type="gene ID" value="CP500_021625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7858" checksum="DDF544B97A90817B" modified="2018-01-31" version="1">MRTSQNKSNLTLTQMVDRILASSKIARREHLILTSAILSDDKISEDERYQVNRIFDYIQTGRLKFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVE8</accession>
    <name>A0A2G4EVE8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapA</name>
        <name evidence="11" type="ORF">CP500_021155</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="NXIB02000187">
        <property type="protein sequence ID" value="PHX53505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53505">
        <property type="protein sequence ID" value="PHX53505"/>
        <property type="gene ID" value="CP500_021155"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="32013" checksum="C0E2763054FB62FE" modified="2018-01-31" version="1">MVKFGRVLTAMITPFKEDGSVNYAVAEQLAVHLVDRGTDSLVLCGTTGESPTMTWDEEYELFQVVQKAVTGKAKVIAGAGSNSTREAIEATQKAAKLGLDGCLQVVPYYNKPPQEGLYNHFRAIAQSSPELPIMLYNIPGRTGQNMLPETVARLAEIPNIVAVKEASGNLDQASQIRCLTPPEFAIYSGDDSLTLPMLAVGGSGVVSVASHLVGEQLQQMIKAFETGQVQVATQIHLQLFDLFKALFLTTNPIPVKTALKLQGWDVGSTRPPLCDCPVEITQKLKDVLSRLAQVSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVF5</accession>
    <name>A0A2G4EVF5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Poly(ethylene terephthalate) hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.101</ecNumber>
            <ecNumber evidence="2">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_020985</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(ethylene terephthalate)(n) + H2O = (ethylene terephthalate)(n-1) + 4-[(2-hydroxyethoxy)carbonyl]benzoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49528"/>
            <dbReference type="Rhea" id="RHEA-COMP:12420"/>
            <dbReference type="Rhea" id="RHEA-COMP:12421"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:131701"/>
            <dbReference type="ChEBI" id="CHEBI:131704"/>
            <dbReference type="EC" id="3.1.1.101"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:49529"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a butanoate ester + H2O = an aliphatic alcohol + butanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:47348"/>
            <dbReference type="ChEBI" id="CHEBI:2571"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17968"/>
            <dbReference type="ChEBI" id="CHEBI:50477"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:47349"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.101" evidence="8"/>
    <dbReference type="EC" id="3.1.1.74" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000182">
        <property type="protein sequence ID" value="PHX53532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53532">
        <property type="protein sequence ID" value="PHX53532"/>
        <property type="gene ID" value="CP500_020985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041127">
        <property type="entry name" value="Chlorophyllase2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010802">
        <property type="entry name" value="DUF1400"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005065">
        <property type="entry name" value="PAF_acetylhydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PTHR10272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12740">
        <property type="entry name" value="Chlorophyllase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07176">
        <property type="entry name" value="DUF1400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1400" evidence="11">
        <location>
            <begin position="42"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="549"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="578" mass="63028" checksum="68C0DD614F461B03" modified="2018-01-31" version="1">MNCLFPSIPLAVRRTRLSFLRKYLGLLAFTAVCTGGTPAFGADRIYVTYGPLEVSVPIESLALFAKVGKIDSNLDGLAQYAKKSQLAQIQLALQARAEISPVTIAQFLYTSQGELLLERLGRVIQTKARQPGFYAIRAALILAASDPEGLTIVNVLRKFPTYGIRIDIDRALGIANELTTLINRSNRAIEGIAKLSEAQAVLEPEIPPAERLQPQLPGPYTWKKSSVTLTSPNRDRTFGLDIYLPQGSPRPAPVVVISHGLGSDRISFEYLAKHLASYGFAVAVPEHPGSNAKQLQDLITGKANEVVEPAEFVNRPLDVKDLLDYLTSLSVSNPAYRGQLDLQRVGIIGQSFGGYTALALAGAQMNFAQLDKDCPLENDTWNISLLLQCRARGLDRSQYNFTDPRIKAAIAINPISSSILGETSLSKIQIPIMVIAGSADTVAPALVEQIQPFTWLTSPNKYLVLMKNGTHFSTIDQSPQSIFRPSADVIGPEPALARRYLNGLSLAFMESYLNNQSQFRPYMASSYAQSISRDSLGLGILRSLTSQQLQELLTSSPPPSRPDSPLSTPQPQAVPLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVI2</accession>
    <name>A0A2G4EVI2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Insulinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_020955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000181">
        <property type="protein sequence ID" value="PHX53539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53539">
        <property type="protein sequence ID" value="PHX53539"/>
        <property type="gene ID" value="CP500_020955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013834785" evidence="1">
        <location>
            <begin position="36"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="2">
        <location>
            <begin position="85"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="3">
        <location>
            <begin position="220"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="493" mass="55064" checksum="15D98F0B8287BE26" modified="2018-01-31" version="1">MKRTKLKLKKVKLFLLSLCFFTVSFSTFNLLPSFAAAPKHYDELKFPELPELKLPKYTRFELKNGMRVYLMEDKELPLVGGTALFRTGDRFEPIDKIGLANLTGEVMRTGGTKKHSSDELNLLLERKAASVETGIGATSGSANFSALAEDVEPVIDLFAEVIREPIFAQEKLDLAKKQEQGGIARRNDNPDNITSREFQKLIYGDRSPYARTVEYKTLANISRDDLVSFYQKYFHPKNMILGISGDFDTAKMRSLIESKFGNWEPTQSAEMPTLPTVSVAKQGGIFLVNQPQLSQSYVQMGHLGGMLNSPDYGALDVMNGVLNGFGGRLFNNVRSRQGLAYSVYAAWSPRFDYPGVFVAGGQTRSDATVPFIKAIRTEIDRIRTEAITPEELAFAKDSKINSFIFKFEDPSQTLARLMNYEYYGYPQDFIFSYRRSIEKATIADVQRVANTYLKPENLVTLVVGNTAAIQPPLSSLGTSVKVQSLDITIPSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVP6</accession>
    <name>A0A2G4EVP6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_31 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000171">
        <property type="protein sequence ID" value="PHX53622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53622">
        <property type="protein sequence ID" value="PHX53622"/>
        <property type="gene ID" value="CP500_020520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="3"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="349" mass="38867" checksum="1BB4D1465FAF69FC" modified="2018-01-31" version="1">MVQKIALFNHKGGVSKTTTTFNLGWMLATKGKKVIIVDADPQCELTEMVLRFSTKQDIEELYKKEQNIKSGLAPVFESRPKLIEAVDCLPVEGCDGLFLLPGHVGFAEYEVTLGIAQELSGSIQTLQNLPGSISYLLQKTADKFEADYILIDMSPNLSSINQNLMMTSDFFILPTSLDFFSVMAIDSLAKILPKWYAWAQKASGMRILQDADYPFPKFTPRLLGTIVQNYKIINGETAADSQKWIDAIEEAVSTKLVPSLRKNNMLLSNQMYNSQGIGSDLCLAKISHFNSLILKSQEHQRPVFALTSDQIEPFGIVVENTLGSQEELKKNFSKLADRVIELTCHAVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVQ5</accession>
    <name>A0A2G4EVQ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cobalt ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_020535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000172">
        <property type="protein sequence ID" value="PHX53614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53614">
        <property type="protein sequence ID" value="PHX53614"/>
        <property type="gene ID" value="CP500_020535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="15"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="255" mass="28703" checksum="C5B884540D761842" modified="2018-01-31" version="1">MPNYSENNTETIPLLRIEGVSFKTPIAPNYLLENISFQVHKGDRVAIVGPSGAGKTTLLRLLNRLSSPTSGSIYLENKEYRQIPAIELRRQITLVIQESKLLGMSVREALAYPLKLRGVNSSNIAERISGAIAQLHIPEEWLTRTELQLSVGQKQLVAIARAIVLKPKILLLDEPTSALDAGKAHHLMQVLIELTNSKTTIFMVNHQLEIAQEFATRVLYFQQGKLLQDAMCDRINWAEMRQKLIKAEAQAEQEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVX8</accession>
    <name>A0A2G4EVX8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (cytosine-N(4)-specific)</fullName>
            <ecNumber evidence="3">2.1.1.113</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_020080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:16857"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:13674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:137933"/>
            <dbReference type="EC" id="2.1.1.113"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.113" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245739">
        <property type="entry name" value="M.Tbo703ORF20080P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53702">
        <property type="protein sequence ID" value="PHX53702"/>
        <property type="gene ID" value="CP500_020080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015667">
        <property type="term" value="F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017985">
        <property type="entry name" value="MeTrfase_CN4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00093">
        <property type="entry name" value="N4_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="7">
        <location>
            <begin position="25"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="426" mass="49233" checksum="B1060D79CF7B72B9" modified="2018-01-31" version="1">MVLSNIFSETPINRQQIPQELLDIEDKQRTNPLPWKGQFSPQFIETLIHKYADKNSVIFDPFLGSGTVLYEAGRFGLEACGTEINPAALILANTYKFIPISPRQRERCINCFLARLKTDIWETMPLFQTIQKELTENDIIDKVVYLAVDNEEKLINILHQALVILLDLENKKVTYSRVFTIAKNLATFVLNLPYSEKPINAYNADARNVPLENSSINLVITSPPYINVFNYHQQYRGSTEALNWKILEVAKSEFGSNRKHRNNRFLTVIQYCLDIAYTLQELLRICSHDSRIIFVVGRESNIKGTPFFNGELVAEVASQVLGISLDIRQERTFLNRYGKSIKEDILHFIKVENLQYYFTIHQARTIAVEALESAYSLADEQVKYEIKDAIDKAEKVQTSPYFERQRSRKIIEKINQKDDVLSRGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVY3</accession>
    <name>A0A2G4EVY3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NfeD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000172">
        <property type="protein sequence ID" value="PHX53616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53616">
        <property type="protein sequence ID" value="PHX53616"/>
        <property type="gene ID" value="CP500_020545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NfeD" evidence="2">
        <location>
            <begin position="29"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10761" checksum="B6A31274EE61B073" modified="2018-01-31" version="1">MFNVVKAFSSIFSTQAYSTQKNMLIDNYINTNFNYFNEEAVVDESICPNQTGRVRFQGSWWPARCDRQITLTPGDTVYVIGVDNITLLVSLVPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVY6</accession>
    <name>A0A2G4EVY6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53712">
        <property type="protein sequence ID" value="PHX53712"/>
        <property type="gene ID" value="CP500_019950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="7240" checksum="6FB8FE745ECE9F17" modified="2018-01-31" version="1">MPTPQENLIFVEQASCLFWRMVQDVIFNQLCIMHLIEIDSCQKWYRFIYSFLLKVCCCSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVY9</accession>
    <name>A0A2G4EVY9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphate transport system permease protein PstA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pstA</name>
        <name evidence="8" type="ORF">CP500_021915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53347">
        <property type="protein sequence ID" value="PHX53347"/>
        <property type="gene ID" value="CP500_021915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005672">
        <property type="entry name" value="Phosphate_PstA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00974">
        <property type="entry name" value="3a0107s02c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="87"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="298" mass="31140" checksum="5A67F1F12126DE36" modified="2018-01-31" version="1">MSNISSEGQTSFASNTGSLKKVKGSQQSLLNSAMTIVAGACLAITLLPLFAVLYYVTVQGFNRLNLDLFTKLPPPPGLSGGGIANAILGTLMTVGIASLIAVPFGVLAAVYLSEFSKGSIARWVRFATNVLSGVPSIIAGVFAYGLFVVNMGGFSAIAGGAALAVLMLPTIVRTTDEALQIVPQDIRWASVGVGASNYQTVLQVVLPAAIPAILTGVTLAIARAAGETAPLIFTALNSPFWPAGFDKPTPSLSVLVYNFATVPFKAQKELAWAASLILVFMVLLTSILSRWATRQKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVZ1</accession>
    <name>A0A2G4EVZ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000171">
        <property type="protein sequence ID" value="PHX53626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53626">
        <property type="protein sequence ID" value="PHX53626"/>
        <property type="gene ID" value="CP500_020525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="282" mass="31998" checksum="A7345BDAD4BAFAE1" modified="2018-01-31" version="1">MTLDPFVRKLAAINQALSALSAETCTTPGCNQPVSKPGHKLCYEHWKANNAQPVSAPKPKPQQSSSPSLLSATSISEKLEISKHKVNPILAELGLVNKEGNGWVATKRGMGFGAVQKTYAQDNTPYVLWPESILTNQVFLATIESLKGDNSEQSKTEVNTKLGFREKFRASAQHRTTDGHFVRSKAEVLIDNWLYMAELVHAYERRLPIEEEVYCDFYIPGGKVYIEYWGYENNPEYLARKKVKQELYQKYELNLIELTDEHIKNLDDYLPRMLLKFGVIVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW01</accession>
    <name>A0A2G4EW01_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TldD/PmbA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000170">
        <property type="protein sequence ID" value="PHX53630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53630">
        <property type="protein sequence ID" value="PHX53630"/>
        <property type="gene ID" value="CP500_020475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD_C" evidence="2">
        <location>
            <begin position="213"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="431" mass="46594" checksum="5DE68FCACF30C7B2" modified="2018-01-31" version="1">MTNHQSAEQLLELATKAGAEAAEVLESQSFSRPVFFEANRLKQLETAQAEGIALRLWRDGRPGLAVAYGPVEPQILVDRAIALSQLNEPEIIELGSSNKIVYPDLGHSIPVEQLVEWGKSAIATIRQAYPESLCTAEFDCEIESTRLLNTRGLDCSHTDTTLSGYLSAELVRGEDFLNIWEGETERSTLDINTITQRVLQRLEWAKDNVAPATGRVPVLFTAKAADLLWGTVCAALNGKQVLEGASPWSDRLGEQVTSPLVTLSQQPDIGPYSCPFDDEGTPTRSIVFINNGVLQLFYTDRTTGRTLGSGTTGNGFRPGLGSYPTPSLFNVLIKPGDRTLNDLIAQLDDGIVVDQMLGGTAGISGDFSINVDLGYRVKKGQIVGRIKDTMVAGNVYSTLKQLVELGGDVEWNGSCHTPSVIVEGLSVTGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW42</accession>
    <name>A0A2G4EW42_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3155 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53753">
        <property type="protein sequence ID" value="PHX53753"/>
        <property type="gene ID" value="CP500_019765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021498">
        <property type="entry name" value="DUF3155"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11352">
        <property type="entry name" value="DUF3155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="12346" checksum="CE1190D66477E4F2" modified="2018-01-31" version="1">MARRRKRKSRRRQEGRRILECVPQYSIESGEDKPVTAARKFIHAEGIAPPALLLVKRNEHTTDRYFWAEKGLFGAQYVEENHFLFPSLKVMLESTAEKISAVSTSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW59</accession>
    <name>A0A2G4EW59_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53708">
        <property type="protein sequence ID" value="PHX53708"/>
        <property type="gene ID" value="CP500_020115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="278" mass="30459" checksum="C5C6CB8B28099922" modified="2018-01-31" version="1">MLELHCHTTYSDGTLTPGELVTAAAASGVRALAITDHDTMSGWDEAFVAALLYNIEIVPGLELSTVHNDRSLHILGFYPDPNKLRVPLNDRIEGRFRRSQEMVDKLAALGYPIELPKTSPGMAPGRPHIASALVKAGHAKSSREAFDRWLGDYGPAYVRYEKFSIAEGIDLLRNCGAVPVWAHPYLFRGGVVEEVLKELVDAGLMGVEVYHPSHSSSQIQKLKDLCLNYGLLVTGGSDYHGPDIERNERKGIQSTALNMLHLPLELLEPIKVAAASLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWF7</accession>
    <name>A0A2G4EWF7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53808">
        <property type="protein sequence ID" value="PHX53808"/>
        <property type="gene ID" value="CP500_019525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013612819" evidence="1">
        <location>
            <begin position="24"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="146" mass="15018" checksum="1640F852A6860BAA" modified="2018-01-31" version="1">MKLNLLAATLLLTPLLLASPARADNPSQVQQLLATGQCFQCDLSGADLRGAHLIGADLRGANLQGANLYQANLEGADLTGANLTGANLTAVFLTNASLNDADLDRANLTAAIINTTDVSGASMEGMVITDAKIYNTQIGVGGSYDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWK6</accession>
    <name>A0A2G4EWK6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_019440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000152">
        <property type="protein sequence ID" value="PHX53820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245737">
        <property type="entry name" value="M.Tbo703ORF19440P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53820">
        <property type="protein sequence ID" value="PHX53820"/>
        <property type="gene ID" value="CP500_019440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="346" mass="38864" checksum="B0A746DAA1F76ED4" modified="2018-01-31" version="1">MSRSISTVDLFCGAGGLTHGFEQAGLTVKAGYDIDPACEFPYEHNNKAKFILQDVANISSSDLAEHFSKGSINILAGCAPCQPFSSYSRRYNDQQLKWTLCRDFARLIEECQPDIISMENVLQLKHHAVFEEFITELKKSNYYFESYEVNCLDYGIPQSRKRLVLLASKFGEINLIPATHQPELYKTVRETIEHLEPLSAGQSSKIDPLHRCSKLSDLNVRRIRASKPGGTWRDWPEDLIAKCHLKKSGKTYPGVYGRMEWDKPSPTITTQCFGFGNGRFGHPEQDRAISLREAALLQTFPPAYQFVAHDKPVGVDLVGRLIGNAVPVKLGIAIARSILEHIHQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWT4</accession>
    <name>A0A2G4EWT4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chorismate mutase AroH</fullName>
            <ecNumber evidence="1">5.4.99.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">aroH</name>
        <name evidence="4" type="ORF">CP500_018480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>chorismate = prephenate</text>
            <dbReference type="Rhea" id="RHEA:13897"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="5.4.99.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.5" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000133">
        <property type="protein sequence ID" value="PHX53994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53994">
        <property type="protein sequence ID" value="PHX53994"/>
        <property type="gene ID" value="CP500_018480"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00120">
        <property type="reaction ID" value="UER00203"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02185">
        <property type="entry name" value="AroH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008243">
        <property type="entry name" value="Chorismate_mutase_AroH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21164">
        <property type="entry name" value="PTHR21164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07736">
        <property type="entry name" value="CM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005965">
        <property type="entry name" value="Chor_mut_AroH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01796">
        <property type="entry name" value="CM_mono_aroH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51167">
        <property type="entry name" value="CHORISMATE_MUT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 2 3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>prephenate</name>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>prephenate</name>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>prephenate</name>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005965-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="15364" checksum="BDFC5F24546AB42B" modified="2018-01-31" version="1">MKNIGVEWQVRAIRGATTASDNSVEAIREVVRELLDELEARNDLNPELIISATFSVTRDLDAVFPAAIARERPRWCNVPLLDVQQMYVKGSLERCIRFLIHVNWPAHTEIYHPYLRGAQNLRPDWSLAVAVAGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWV0</accession>
    <name>A0A2G4EWV0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Elongation factor P</fullName>
            <shortName evidence="7">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">efp</name>
        <name evidence="11" type="ORF">CP500_018340</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 8">Belongs to the elongation factor P family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54032">
        <property type="protein sequence ID" value="PHX54032"/>
        <property type="gene ID" value="CP500_018340"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00038">
        <property type="entry name" value="efp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="10">
        <location>
            <begin position="67"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="9">
        <location>
            <begin position="129"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="185" mass="20684" checksum="33598BB4DCD93C3E" modified="2018-01-31" version="1">MISSNDFRSGVSIEWNGGVWRVIEFLHVKPGKGSAFVRTKLKNVQTGNVVENTFRAGESLPQANLEKSAMQHTYKEGDQFVFMDMESYEESNLTAKQIGDRVKYLTEGMEVNILRWNDQILEVELPNSVILEVTQTDPGVKGDTATGGSKPAILSTGAQIMVPLFISIGERIRIDTREDKYLGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX92</accession>
    <name>A0A2G4EX92_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF262 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54153">
        <property type="protein sequence ID" value="PHX54153"/>
        <property type="gene ID" value="CP500_017660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="DUF1524"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="DUF1524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="15"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1524" evidence="2">
        <location>
            <begin position="424"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="566" mass="66121" checksum="2E9F6A564567A3FF" modified="2018-01-31" version="1">MARTNLLETRTTSFGDLIGNGKIYRVPPFQRDYSWTEENWEDLWQDILMLHNNLSVSHYMGAIVLQSSATADKEFTVIDGQQRLATLSIIAVAVIEKIRLLVEQNVQPEANRERQEILKRTYLGDRDPRSLRYSSKLFLNENNDDFYQSNLVNLRKPLNIRSLSKSNQLLWQAFDYFSQELEKMPDIFQDGEKLTAFLGDTVAQRLLFIQISVEDELNAYTIFETLNARGLELTSTDLLKNYLFSLFQGPDDLKAAQRQWKRIINMVQMEEFPAFLRYYLSLNYSRVRRERLFKLVRESVKNAQQAFDLLDKLENFSSLFVALGSPNDEFWRDTPQNQPYIRALNLFRVKQVYPTLFAAYQKFSAEDFTRLLKLVVAISFRYSIVSSLNPNELELLYNNAALDITSGKITGTRQVFDALRPGYVKDEKFQQDFSLLSLSTKGQKRKLVRYIFCNLEADESGIEVNEDSFSIEHILPEVPTDEWRQNFTDVQIEEMVYRLGNLSLLEPSFNRDIGQKNYHIKREKYQQSVYALTKNILAEDWTPDAIAARQRNLARRAVHIWQSDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXF0</accession>
    <name>A0A2G4EXF0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerophosphodiester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54156">
        <property type="protein sequence ID" value="PHX54156"/>
        <property type="gene ID" value="CP500_017675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="3"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="237" mass="26315" checksum="A62B3FC001F58AEB" modified="2018-01-31" version="1">MSLEIIAHRGFSSIAPENTLAAFEVAIARGASSIEFDIQLSADSVPVIFHDATLDRITGVSGKVRDKNLSQLQTLDAGKWFSDEFSGEKIPTLKEALNILKKVDKFLYFDVKPHCEWSDSEVADFVKTLQDAGIPEKCVMTSFNDGFLEQVRQISDDLPIGHIVANLEAYKSQLAQAVVKGDRLLSTLYHVLLENPALIAESRRQGVDIVAWTVDDREDLRKLLDLGITRIVTNCLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXK6</accession>
    <name>A0A2G4EXK6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_017095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54251">
        <property type="protein sequence ID" value="PHX54251"/>
        <property type="gene ID" value="CP500_017095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="8"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="315"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="348"/>
            <end position="355"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="567" mass="62869" checksum="5A7681F2E2298F21" modified="2018-01-31" version="1">MTNDSSLFSIENLRVAYPQRRGQSGWAVDGVSLTLQPGEKLGLVGESGCGKSTLGRAAMRLLPESTLIEGRVGFAGESVFEMNASRLRRFRGEAVALIFQDPMTRLDPLMTVGQHCVETLQAHRPNLSKAEAKKRAIAILEAVKIPASRWSQFPHEFSGGMRQRVAIALALLLDPKLIVADEPTTSLDVTVAAQIMQELTRLCAERGTAILLISHDLAMVAEYCDRIAVMYGGQVVETGPVDRVFQQPQHEYTRSLLKAALHIQKEEGSSATDCVTDVTDVTDRGEKENYRLKSELNSPLLTVTNLQQHYSLESNLLEQLFSRNRAVIKAVDGVNFELERGEILGLVGESGCGKSTLSRTILQLIPATGGRVEFQGIDLTALASDAVRKHRRQMQMVFQDPHACLNPMMTVGESIADPLFIHKLANAPEAKRQVIQMLERVGLTPGEDFFRRYPGELSGGQQQRVSIARALITRPQLIICDEPVSMLDASVQTQVLELMLELKQEFNLTYLFITHDLWVARFFCDRIAVMNAGKIVEIGKTRDIFTNPQHPYTQQLLQAAPLLARTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXU2</accession>
    <name>A0A2G4EXU2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54355">
        <property type="protein sequence ID" value="PHX54355"/>
        <property type="gene ID" value="CP500_016505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="207" mass="22285" checksum="8989A0E3872040E5" modified="2018-01-31" version="1">MSLKFISIPPTTDRKPVALIVSLHGWGANARDLTSLAPAFNLPDYQFVFPDAPLNHPQVPGGKMWYDLQGNDSKGLLESRQLLKEFLLSLESSTGVPLSRTILGGFSQGGAMTLDVGLTLPLAGLICLSGYLHSMSPVVGSVLPPVLIVHGTQDSVVSVSAAIRARDSFTAWGASVQYHEFPMGHEIKPEIIDLMRSFVLETVSKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXU3</accession>
    <name>A0A2G4EXU3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016645</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OprB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54341">
        <property type="protein sequence ID" value="PHX54341"/>
        <property type="gene ID" value="CP500_016645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013426874" description="SLH domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="4">
        <location>
            <begin position="177"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="74"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="662" mass="70828" checksum="E5B87516FEB2EDC7" modified="2018-01-31" version="1">MNTLVYKTLVVTLTVLGSGLMPGAIAQAVDSPITEQPTASPTNSEETEPQINVQAEALPESVVSAEKVGDNSLNGVLLPTTTNQEIPTQKAEDFNQDLSLNQDRGSSRAKENSLVSNPSPENTLTEQVIPISGQTAELPQQDTSLFDHILPARGNTVNPLLDKKTSEDNTSIDQVTSVSQLSDVRPTDWAFQALQSLVERYGCIAGYPDGTFRGNRAMTRYEFAAGLNACLDKVRELITTGTINLATKEDLGIVQRLQEEFAAELATLRGRVDTLEARSAELEANQFSTTTKLNGQVLTYLGDAFGKNASEANNTAFGYRVRLNLNTSFTGKDNLLVGLEATNLRRLNAATEFPQSRLRGATDETLFSATNTSGDGSFKLNALQYTFPVGDKLQVFLNAFSSDRILSAPLSPFSSSTTGSISYFGSMNPILYPTGQQTGIGVQWKATPWLNVDFSAGSESRTNDPTVGLFSGGYSGSVRTVFTFGALNLALNYIHFYSPQFGADTASGSNAAKVVGAGPVVGNAYLPGISYRVSPTLGLSGSVGLINARALGNGTKGDANVLDYRFSMAFYDIGKKGNLAGIVFGVQPRLTNTSNGAIAQAIGLPAGQRRDRDMGFHIEAFYTHLLTDNITITPGIIWLTAPNHDARNPDVVVGVVRTTFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXY9</accession>
    <name>A0A2G4EXY9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_018310</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54027">
        <property type="protein sequence ID" value="PHX54027"/>
        <property type="gene ID" value="CP500_018310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="289" mass="30324" checksum="DB4E67128B514DE0" modified="2018-01-31" version="1">MTTSELLILGAAGLFAGILAGFLGIGGGTMLVPLLVALKYEPLQAVATSGLSIAITAISGSFQNWRMGYFSLSQVAGIGFPAVITAQIGVYLAGIFPPYLLLIAFGLLLLLNIYLIEVRKSLTNQHKSAEGQEEIGGQTGQGENSPLPNPDSRFPNHANILFNPTFAKIATGSVAGLLAGLFGVGGGVIMVPLQTLLLGESIKTAIQTSLRVIVITAISATLGHAARGNVLWAVGLILGAGGLLGAQVSTRFLPRLSDRTVSLAFRSLLALLSVYVFWQAWQQFSQKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY44</accession>
    <name>A0A2G4EY44_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GAF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_017985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54087">
        <property type="protein sequence ID" value="PHX54087"/>
        <property type="gene ID" value="CP500_017985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009584">
        <property type="term" value="P:detection of visible light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013515">
        <property type="entry name" value="Phytochrome_cen-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00360">
        <property type="entry name" value="PHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="1" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0716">Sensory transduction</keyword>
    <feature type="domain" description="PHYTOCHROME_2" evidence="6">
        <location>
            <begin position="32"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="PHYTOCHROME_2" evidence="6">
        <location>
            <begin position="518"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="711"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="672"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1000" mass="112474" checksum="14CB1A09729DDB0A" modified="2018-01-31" version="1">MKLIEEPERLNHKLNREVLVRRITERIRQSLESEDILSCTVEEVRSFLKTDRIMIYKFSSDGSGEVVAESIDRHRLPSLKGLNFPADDIPPQAREMYVSLRQRTIVDVKSATIALSPLDAPHTGEPLGTDEIYYRSLDPCHRAYLMAMGVQSSLVVPILHRRSAPANSKTDTCESAECVTRYDGENTSQTHIELWGLLVSHHSTSRKMYQTDLEVIQLVVDQLSIAIAHSVLLQQTRSQTALEATVSRIATLLYGQSNIQLQQALEATVTAMQGSGGRLYISAPKISPEKLSIPKIDREFEISTNTDSADSAFELFATGEQPILPDWENANAIEAHPLWQQLLTKGLTNTADISQLPTGSPFPVWVVTDLYKEPLFRVLVPAFKDTKIRGLLVIPLHCQQQLIGCLTIFRNEIDTETMWAGRFDTSVQQMLPRQSFEVWREIKKGQSSQWKWHEIEQAKAIGSQFCSAIQQYLLHQEVQALNANLERQVQERTAQLQKSLDFAKVLTRVRDQIRSSLDLKTILQTIVREVRVLLDTDRTVIYQFAEEKQGEVVVEEVRGEWQSILGVKSPEGCFGEGSLCFYKQGKVRAIHDIYNADLTPCHQEFLESLQVRGSVIVPIGQDTQFWGLLIVHECCGPRVWQTAEQELLQDLADEAAIAIHQAELYQNSLNAAAAYQAKAKQLAKALAQLQNTQAQLIQTEKMSSLGQLVAGVAHEINNPVNFIYGNISHANEYSRDLLWLVELYRQHTPSPNLEISECEEAIEVDFLAKDLPRILDSMKVGAERIRQLVISLRNFSRLDRAEKDCVDIHEGLESTLLILQHRVKATSDRDTIEIIKEYGNLPQVDCYASSLNQVFMNILGNGVDAIEMQNIERGTSLVRLEKRAAAINFSSQEVATNSENLNVTNECLIPDVPYPCIRIRTQLIDKNTVGICIADNGHGIPKELISHIFNPFFTTKPVGQGTGLGLSISYQIVVEKHKGVLKCISLPGQGTEFWIEIPIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY54</accession>
    <name>A0A2G4EY54_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Multi-component transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_016025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54463">
        <property type="protein sequence ID" value="PHX54463"/>
        <property type="gene ID" value="CP500_016025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="7">
        <location>
            <begin position="125"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="6">
        <location>
            <begin position="263"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="379"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="504"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="125"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="2">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="634" mass="71145" checksum="847A44412C04229A" modified="2018-01-31" version="1">MKVLIVEDDKLTVNLLARSLDAHNYTFNTAGDGETALQLAQTYDYDLILLDVMIPKLDGISVCRQLRACGYQMPILLLTALDSSVDRVKGLEAGADDYVVKPFNLPELIARIRALLRRGKTNLLSPNLTWEKLQVNLDIAEVTYEEKVLHLTPKEYNLLELFLRNPRRIFSRSAILDRIWSAGEFPQEEAVTAHIKGLRQKLKAAGMIVDLVETVYGLGYRLKSLPEEFDRPTAESANSQEILSAKARGVIDELNTNSHQAKVLAVVAEIRANFQASFAAKVEIFDRAIAKLNTGTLDNEMRQQAQSQAHKLVGSLGTLGIPKGSEIARKLENLFKTENISKPGAYWQIEELVNLLKRSFDLPTTEPESDPVVVSGNRQMLIIDDDVLQIDRLKTEASAWKFHIEVANSPQAAKIALSQHPPDAILLDLNFSRTQENGIPLLAELLRQKPEIPVMVFSEYNQLSDRIEVARLGASGFLHKSIPPADILKAVDRILDQTSPAEAKVMVVDDDVDLLAAMTIILQPWGFQLTTLDEPERFWEVLETTCPDLLILDVEMPGYSGIELCLAVRNDLRWSRLPVLFLTAHSESEIVRQMFVAGADDYVNKPIVEPELIARILNRLERIKLRYKLALTQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY56</accession>
    <name>A0A2G4EY56_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bis(5'-nucleosyl)-tetraphosphatase (symmetrical)</fullName>
            <ecNumber evidence="2">3.6.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016095</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = 2 ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24252"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.41"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.41" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54451">
        <property type="protein sequence ID" value="PHX54451"/>
        <property type="gene ID" value="CP500_016095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005249">
        <property type="entry name" value="YqeK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00488">
        <property type="entry name" value="TIGR00488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="4">
        <location>
            <begin position="22"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="211" mass="23464" checksum="041A5F888B119E9B" modified="2018-01-31" version="1">MILASTRDRVLTWLSDHVPAARITHILGVEQSAGDLARLYGLDEAKARSAGLLHDLAKYFKPQLLLQMAKAEGLELDSVLVAHPHLLHADVSAIVAREEFGVVDREILEAIANHTLGRPNMSQLSCTVFIADTIEPSRGNTPELEALRQASVQNLYAAVWQTSDYSLKYLLATRCYIHPRTVLTRNWALQMARESPEIGNLTRESIEQITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYK1</accession>
    <name>A0A2G4EYK1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NYN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54604">
        <property type="protein sequence ID" value="PHX54604"/>
        <property type="gene ID" value="CP500_015105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="22"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="22705" checksum="8E1E1458FB47E672" modified="2018-01-31" version="1">MLNRIESNDLFTPEQVLENRGRVAIFIDGSNLFYAALQLGIEIDYTKLLCRLTAGSRLLRSFFYTGVDRTNEKQQGFLLWMRRNGYRVISKDLVQLPDGSKKANLDVEIAVDMMALVGSYDTAVLVSGDGDLAYAVDAVSYRGVRVEVVSLRSMTSDSLINVADRYIDLEMIKDDIQKTSRPNYAYRPLSGLSLMDEHDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYK6</accession>
    <name>A0A2G4EYK6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LD-carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_015130</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54609">
        <property type="protein sequence ID" value="PHX54609"/>
        <property type="gene ID" value="CP500_015130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S66" evidence="4">
        <location>
            <begin position="16"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="5">
        <location>
            <begin position="185"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR028757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="312" mass="34136" checksum="22E33D08351C4880" modified="2018-01-31" version="1">MTNIKFLQPGDLLIAISPSGTLRELTNFERGIEIWKSRGYRVELSPGFDSRWGYLAGSDENRIRQLADALNDPDCRGILCVRGGFGSTRLLEKGKVAEAKNAPFPMPDSLFPMPDAHFPKWLIGFSDITALLWNHAKLGIWGVHGPLLTTLAAEPDWSVDRLFDCIEGRRLPPLSGKGWGGGKATGRLLPANLTVATHLLGTPYLPDLTGVILAFEDVSEAPYRVDRMLTTWRMAGAFVGVRGIALGRFSRCEVDPKIPSFSIEEVLRDRLFDLNIPIVSDLPFGHDGVNAALPVGIMATLDADSGLLICDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYL3</accession>
    <name>A0A2G4EYL3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54619">
        <property type="protein sequence ID" value="PHX54619"/>
        <property type="gene ID" value="CP500_015180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11528" checksum="31F891E11757FBB8" modified="2018-01-31" version="1">MTLSEMGYFIFLYAIALYARSVIRNKKGRSLLMREGRSVIRNNKGRSVSVESSYSLVFGVKGDRSFILGDRNSCNHRTGMVEMDKIVSKKEVGLIKGNPTYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYQ9</accession>
    <name>A0A2G4EYQ9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fifty-four homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ffh</name>
        <name evidence="10" type="ORF">CP500_015125</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54608">
        <property type="protein sequence ID" value="PHX54608"/>
        <property type="gene ID" value="CP500_015125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="9">
        <location>
            <begin position="268"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="444"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="107"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="189"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="247"/>
            <end position="250"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="478" mass="52340" checksum="73F8D48285B2C8C3" modified="2018-01-31" version="1">MFEALADRLESTWKKLRGQNKISESNIQDALKEVRRALLEADVNLQVVKNFISEVAAKAQGAEVVSGVRPDQQFIKIVHDELVRVMGETNVPLATADSGPTVILMAGLQGTGKTTATAKLALHLRKQNRTALLVATDIYRPAAIDQLLTLGKQIDVPVFELGTDTDPVEIARQGIEHGKQLGIDTIIVDTAGRLQIDQDMMAELLRIKQTVQPHETLLVVDAMTGQEAANLTRTFHEQIGITGAILTKLDGDSRGGAALSVRQISGAPIKFVGVGEKVEALQPFYPDRMASRILGMGDVLTLVEKAQEEFDIADAEKMQEKMLTAKFDFTDFLKQTKLLKNMGSLGGIMKMIPGMNKLSDEQMRQGEVQLKRTEAMINSMTTEERRNPELLASSPSRRRRIGRGAGYAENDVTKLVSDFQKMRTMMQQMSQGNFAGMGGMPGMPGMGGGMQPGSRGYMGGQQKKKKKKDKPKKGFGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYR1</accession>
    <name>A0A2G4EYR1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5-oxoprolinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54659">
        <property type="protein sequence ID" value="PHX54659"/>
        <property type="gene ID" value="CP500_014975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydant_A_N" evidence="1">
        <location>
            <begin position="13"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="245" mass="27314" checksum="E08FCE870588680A" modified="2018-01-31" version="1" fragment="single">MNTDFCDRTGWQFWIDRGGTFTDIVAKCPDGTLVIHKLLSENPDRYTDAAVQGIRDILGISADVPIPAAQIEAIKMGTTVATNALLERKGDRTILLITKGFGDALRIGYQNRPNIFARHIVLPEMLYDRAIEVAERYSATGEELIAVNREFIPSLQQAYDEGIRSCAIVFMHGYRYSQHEQQVAEIAKEIGFTQISVSHEVSPLMKLIFRGDTTVVDAYLSPILRRYVEQITSQLSVGAVPPCPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYT9</accession>
    <name>A0A2G4EYT9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cofactor assembly of complex C subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54684">
        <property type="protein sequence ID" value="PHX54684"/>
        <property type="gene ID" value="CP500_014800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021325">
        <property type="entry name" value="CCB2/CCB4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044705">
        <property type="entry name" value="CCB4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34943">
        <property type="entry name" value="PTHR34943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11152">
        <property type="entry name" value="CCB2_CCB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="216" mass="23852" checksum="DB705B80C4CD0CB8" modified="2018-01-31" version="1">MTKSDPNRVLRQLPLVAGGLAGTLLMVNRLLTEQLTDSQARSDALGVIISALLILTGLLWQQVQARSPDSVNLIGEEGFEYTPDLPDVVKIELAWASRLLLTNTATRAIVILYQGKVLLRRGILGINPEVKPGPILQRVFDKNKPVYLVNLNIYPGKIEFDYLPENTQGVICQPIGNQGVLILGANAPRSYTKQDENWVEGIADKLDNTLSQHLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYZ3</accession>
    <name>A0A2G4EYZ3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Photosystem II reaction center protein M</fullName>
            <shortName evidence="8">PSII-M</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">psbM</name>
        <name evidence="9" type="ORF">CP500_014710</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cellular thylakoid membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PsbM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54706">
        <property type="protein sequence ID" value="PHX54706"/>
        <property type="gene ID" value="CP500_014710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00438">
        <property type="entry name" value="PSII_PsbM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007826">
        <property type="entry name" value="PSII_PsbM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037269">
        <property type="entry name" value="PSII_PsbM_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05151">
        <property type="entry name" value="PsbM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161033">
        <property type="entry name" value="SSF161033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03038">
        <property type="entry name" value="PS_II_psbM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="2 8" id="KW-0674">Reaction center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="37" mass="4182" checksum="77D9D789467E2FA6" modified="2018-01-31" version="1">MEVNQLGFVATILFVLVPSVFLIILYIQTASREGRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ06</accession>
    <name>A0A2G4EZ06_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54754">
        <property type="protein sequence ID" value="PHX54754"/>
        <property type="gene ID" value="CP500_014320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="13472" checksum="DE5723708B5EB65F" modified="2018-01-31" version="1">MDIESTKVTPEEIAKFRTELASYPSAIAALDVIEEECEGYLEDAIPLLLMRETSTEADRSLGDLLEKCRKFICQEEVREALESGMIAPAIEPISMGAGIPPGVATAVGICAFKLGMKKVCADCTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ42</accession>
    <name>A0A2G4EZ42_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54794">
        <property type="protein sequence ID" value="PHX54794"/>
        <property type="gene ID" value="CP500_014090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="SSF56726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="451" mass="50369" checksum="30FC2B620A3BC4D4" modified="2018-01-31" version="1">MGMKCVQCNTDNDLSDRTTNSGKCINCNHPFVFDPATITEKKFAFTDPFFQKAIADISSQNMLFFTPKQFLYLIDKRLKYPASANRWAWINPYFILLAILLIFSILFIGILFPQLMNFIIATHLSLMLLVLFVIYNSVWMGIFFANTKSIHQGIIGRKNNAKNLQVLGGIILVAGISVSLIANYFPGYIAAAALGLFSCWLGTSQKNRKQGFTELFLVNQAQSDEWLQRWQTVNGALEKLLPAPRQEALPASIDPEVSAYSFDRAIICDNDEIAQFLIANNVHFENNCAILSISGYPQSIFDTVIEMLRRNADLKVYALHDANPAGVSLVHQLRTSPNWFADQVVTIFDLGISPRQILETRDMFVQQSQTMAQSARQLPNAVRQGLTAQELAWLDAGNFVELESFTPQRLLRVVNYGLAQSGDPQGNEGLILVDDNVGYGGGYVFVSDSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ52</accession>
    <name>A0A2G4EZ52_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="18">NADH-quinone oxidoreductase subunit L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CP500_014135</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I subunit 5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54802">
        <property type="protein sequence ID" value="PHX54802"/>
        <property type="gene ID" value="CP500_014135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002128">
        <property type="entry name" value="NADH_UbQ_OxRdtase_chlpt_su5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018393">
        <property type="entry name" value="NADHpl_OxRdtase_5_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01010">
        <property type="entry name" value="Proton_antipo_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01974">
        <property type="entry name" value="NDH_I_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="6" id="KW-0874">Quinone</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="508"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="558"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="662"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="16">
        <location>
            <begin position="75"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="15">
        <location>
            <begin position="141"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_C" evidence="17">
        <location>
            <begin position="493"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PHX54802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="681" mass="73910" checksum="C0454C594DE12673" modified="2018-01-31" version="1">MELLYQYAWLIPVLPLAGAMLVGLGLITFNQATNKLRQANAILIVSALGGSMVLSFALLWSQLQGHAPYTRTIQWASAGDFSLNMGYVIDPLTSVMLAIVTTVAFLVMIYTDGYMAHDDGYVRFYAYLSIFSASMLGLVVSPNIVQIYIFWELVGMCSYLLVGFWYDRKPAADACQKAFVTNRVGDFGLLLGILGIYWATGSFEFEVMGDRLHSLVESGALSATLATIFGVLIFLGPAAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGVFLIARMYPVFEGLPAVMNLIACTGCFTAFMGASIAITQNDIKKGLAYSTISQLGYMVMAMGVGAYSAGLFHLMTHAYFKAMLFLCSGSVIHSMEDVVGHNPALAQDMRVMGGLRKYMPITATCFLIGNLAICGIPPFAGFWSKDEILAQAFAANPALWAVSWVTAGMTAFYMFRMYFSTFEGEFRGNDNAIKQQLLQPGLVFGPGAMNVKELASTGESHDAHDHFPHESPLTMALPLVVLAIPSVLIGFVGTPFANYFEQFIHAPGESLEEVLEHAAEFDLTEFLIMGGSSVGIALLGITLASLMYLSRKIDAGAIAQKIKPLYEFSLNKWYLDDINEVLFVQGSRRLARQVMEVDLRVVDGVVNLTGFLALVSGEALKYIENGRAQFYALIVFVAVLGLAIVSGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZH6</accession>
    <name>A0A2G4EZH6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <shortName evidence="5">HMBPP reductase</shortName>
            <ecNumber evidence="5">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ispH</name>
        <name evidence="6" type="ORF">CP500_013585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54914">
        <property type="protein sequence ID" value="PHX54914"/>
        <property type="gene ID" value="CP500_013585"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="317"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="401" mass="45319" checksum="45AB9F8687CB9D07" modified="2018-01-31" version="1">MDTKAFKRSLQQSENYHRKGFGHQAEVADVMNTAYQSSLIQQIRDNNYRLERNGVTIRLAEAFGFCWGVERAVAIAYETRQHFPTERIWITNEIIHNPSVNQHLRDRSVGFIAVEQGQKDFSVVDRGDVVILPAFGASVQEMQLLNDKGCKIVDTTCPWVSKVWNSVEKHKKKDYTSIIHGQYKHEETVATSSFADKYLIVLNLHQAEYVSNYIINGGDRDEFMAKFSNAYSAGFDPDVDLERVGIANQTTMLKSETEQIGKLFEKTMMRKFGPDNLNEHFLSFNTICDATQERQDAMLDLVEEKLDLMVVIGGFNSSNTTHLQEIAIDKTIPSYHIDCAERILPGNRLEHKPLGGDLVIAQNWLPEGKIVVGITSGASTPDKVVEDAIDRIFERKATAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZR3</accession>
    <name>A0A2G4EZR3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX54999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54999">
        <property type="protein sequence ID" value="PHX54999"/>
        <property type="gene ID" value="CP500_013025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="16"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17361" checksum="3E4F46FC29BAD829" modified="2018-01-31" version="1">MLTSVERLLFVRAVPIFKELRDDFLVRLASVMDELSFPSKHTIFTEGQEGRSLYILVSGTVRVHIGDRDLAQLKAGACFGEMSLFDAEPRSASITALEPCECLMLTQMQLYDAIDETPGIAVNIIRLLSRRIRELNQKLNAKEVVLSVPDPVVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZW1</accession>
    <name>A0A2G4EZW1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55049">
        <property type="protein sequence ID" value="PHX55049"/>
        <property type="gene ID" value="CP500_012845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="256" mass="28397" checksum="BDE160B12D694D19" modified="2018-01-31" version="1">MKLTRIDLNSWIFHLAGQTILVDPWLVDPLVFYGQPWLFTAYHNTPVAFTPDTLPPIDLILISQGLDDHCHRPTLSKLDRTIPAIASPSAAKVLSSLGYTNITSLANWQEFNYQEKLQITAVPGAEIQPGQEENGYLLKDLNSGETLYYEPHLPPLEKVKQKIDRVDVAIAPVIGQIFPFLGQIIMGPSQALSLAQTLKPRFFVPTTMGDIRATGILPMFVRSIGSIPEFRELLTKSGLATQLLEPDPGQTLEITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F045</accession>
    <name>A0A2G4F045_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="3">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fabD</name>
        <name evidence="6" type="ORF">CP500_012145</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fabD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55130">
        <property type="protein sequence ID" value="PHX55130"/>
        <property type="gene ID" value="CP500_012145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="5">
        <location>
            <begin position="7"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000446-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="292" mass="31939" checksum="04AB3B8D665D8DE6" modified="2018-01-31" version="1">MTKTAWVFPGQGSQAIGMGADLLNLPKAKAKFELAKEILGWSVPDVCQEEAKLSRTLYTQPCLYVVESILVDLVREKFDRPAVVAGHSLGEYVALYAAGVFDFETGLRLVKRRAELMDNVSGGQMVALIGFDRQELELQIQYSRDVVLANDNSEAQVVISGTPTAVEELLAKIKVKRAVKLNVAGAFHSPLMSSVANEFQQVLKSVRFSDAKMLVLSNSEPMATTSGATLKQRLTQQMTKGVRWREISLQLPQQGIDRVVEIGPGKVLTGLIKRTTPDLKLVNVSSLADLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F084</accession>
    <name>A0A2G4F084_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55182">
        <property type="protein sequence ID" value="PHX55182"/>
        <property type="gene ID" value="CP500_012430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="241" mass="27403" checksum="4B45D1CF49A9D94B" modified="2018-01-31" version="1">MASGLKPSTLELLKRFNRAFPQFYEQFVSSEIQLQNLKLAYQLYKTRQAVIEVRPEGNKSALHFAYRNQSFLLSDIFGVLAAYGLTIHSLSLYGQIYPPMLVFIKLVVSRGGKVLADKTAENVCRAVREALAGHFEVEEMLAVEFNLDAGLEDVATEFYVDPVFHLPALLIEAENQPGLFYKVMYAIWQEDLLVVNANLLVWRGRTRLILYLLGPNESLIPEYLGQKIAEGVRQRLLGDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F093</accession>
    <name>A0A2G4F093_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55181">
        <property type="protein sequence ID" value="PHX55181"/>
        <property type="gene ID" value="CP500_012425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045039">
        <property type="entry name" value="NSI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43626">
        <property type="entry name" value="PTHR43626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="49"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="184" mass="20931" checksum="0B7F0CA96BB40B43" modified="2018-01-31" version="1">MGFWKNLFSSSESASVPQTADFEEDVAVGSGDLLSPTFRKPTSLGNARIFFSCDRDIDLYELEELCNAVGWSRRPLRKVKKAILHSFLVVSMWEMRGTQRRLIGFARATSDHAFNATLWDVVVHPDYQGKGMGKALMKYIIKKLRSEDISNITLFADPQVVNFYQNLGFMSDPEGIKGMFWYPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0A4</accession>
    <name>A0A2G4F0A4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="5">RF MTase</shortName>
            <ecNumber evidence="5">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">prmC</name>
        <name evidence="8" type="ORF">CP500_012405</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55178">
        <property type="protein sequence ID" value="PHX55178"/>
        <property type="gene ID" value="CP500_012405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="7">
        <location>
            <begin position="29"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltranfer_dom" evidence="6">
        <location>
            <begin position="124"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="133"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="202"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="32852" checksum="2D3A98448A2592CD" modified="2018-01-31" version="1">MPIFVSGLELWKWIDRAKVEAIASDVSLTELEWLLQELTSLDKLALRLESFKDLPKVELNLSLAEIAQLWERRLQERVPVQYLTGTTYWRDFSLKVTQAVLIPRPETELLIDLAVEALKPDRLNSKSNWVDLGTGSGAIAIGLASVLTNSTIYAVDFSAAALAVAQQNAENLGFGDRIKFDRGSWWEPLEFLKGQVSGMISNPPYIPSSTVLTLQPEVTKHEPHLALDGGGDGLDCIRHLAATAPDYLESGGIWLVEMMAGQAEAVVEILESHGSYCQVQIFADLAGIDRFALAYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0E3</accession>
    <name>A0A2G4F0E3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_011895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55234">
        <property type="protein sequence ID" value="PHX55234"/>
        <property type="gene ID" value="CP500_011895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="3"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="95"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="200" mass="21682" checksum="8C382E4B2162D3C9" modified="2018-01-31" version="1">MAFELAPLPFAADALESGHMSANTFSFHHDKHHAAYVTNLNKLIEGTELASKSLEEIVVASSKDSSKAGIFNNAGQVWNHNFFWNSLKAGGGGTPTGALADKITADFGSFDEFKAEFKAAATTQFGSGWAWLVLDNGTLKVTKTANADTPLAHGQIPLLTLDVWEHAYYLDFQNRRPDYIANFLDNLANWDFAAANLAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0H4</accession>
    <name>A0A2G4F0H4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_011775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55253">
        <property type="protein sequence ID" value="PHX55253"/>
        <property type="gene ID" value="CP500_011775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TOG" evidence="4">
        <location>
            <begin position="16"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="4">
        <location>
            <begin position="262"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1049" mass="114826" checksum="16C157A775FE0554" modified="2018-01-31" version="1">MTKHYRQRLVAVIALSFLSFTSPLLLIRNAAAENLSASKASSQEINSLIKKLKTNDERELDAAIEKLGKIGEPAIPALIEALRDRNLLVRKSAAQILQQFGTPTILALVQASKDSDAKLRRRAATLLNKMAYGTPLVSSEAKNVIPQLISLLKNSDADVRSSAALFLGSVSGETKTVMPQLIPLLKDSDAGVRSSAALFLMSVSGETKTVMPQLIPLLKDSDAGVRRSASDVLGSIGAEAKTALPQLIPLLKDSDAGVRGNTASALGRIGGQAKTVMPQLIPLLKDSDAGVRRSAASALGEIGAEAKTVVPLLLPLLKDSNANVRYDTANALRSMGAEAKTAVPQLISLLKDSDADVRIIAASILAGIGAEAKTAVPQLVSLFKDSNADVRSKAASALGSIGAEAKTAVPQLVPLLKDSNKDVRSDAAFVLGSIGAEAKTAVPELVSLFKDSNADVREDARMRIIAFDALVSIALSLQEKAKTLTPSELNQAVSNLESALKMLEQSKHKDRDKLYFSSSDSKTNIANLRVYLNILKAEQRDRLFVKSIIQNPYIWGTGIYLFLLFGTFAIRPLWLLKIYETLKPIGFKIPVLGTDVSLGNLIFFKYHPRVLDAWVAAHIQATRDEFQKRETVRDRKILVPIPVILDNNTIPTLKGKDLQPTFAQKRGCLLIWEEGGAGKTSLACQIGKWAMSDNPEERICNHRMLPVLIEEELNMKVAEGKQPFIEGIRGQLQDLTDTTEPISEELLEKLLKQRRILVIVDHFSEMSEQTRTAIKPEMPDFPVNALLVTSRLEESLGRVTKTAIKPLRIAGNRLSSFMESYLNQRQKRDLFSDTEFFNACIQLSTIAGDRNITVLLAKLYADQLIAKKEGTTDGNLPDNIAELMLHYLNQLNRSVTENKLSDATVHKDAKIIAWECLKQTYRPAAANCQNAIDALGADNPESRIKYLEEKLRIIQTKGVSHDQIHFALDPVAEYLAALHLLDINKDESKWQDFLKVADSQNSPEGIKGFMLAVKDCYLDKVPSAKDTDFLPKQIASRYNVIITAVPVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Q5</accession>
    <name>A0A2G4F0Q5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_011400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55343">
        <property type="protein sequence ID" value="PHX55343"/>
        <property type="gene ID" value="CP500_011400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calx-beta" evidence="3">
        <location>
            <begin position="248"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="3">
        <location>
            <begin position="362"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="603" mass="61498" checksum="2BED8E602E65E322" modified="2018-01-31" version="1">MATPFNGSLGQTTNFSTINDLIAKWATASQNKGIKLSGIAVDGVETDYLNPTAIGNLTLATNVNPQSWLSYGSTGGIGVASAYDGWFTDVNKVRAEINHNPNTNQSQALKVKWADNQDVTSATIDLSSLSVKTAPGVGDQGNEVGLLQVFNNGVLVPTSNFTFTRLNAPIAPKPLSVSANGVTFTGDRNDGSFKFKVEAKPNTGAAFDELRFSAKAYDSPTAAYANTPTPFKDDSSDYLVRNIQYQGIDVTPTPTPTPTPASVFQFEQGSYTVNEGGVATINVTRTGGTAAASINYATVNGSAKAGGTAPDYTVAAGALNFAAGQTSASFTVTALNDLIFESPETVNLVLSGGNIGSNPSILTINDVVPTPTPTPTPTPGQNTFSFSAAAYSVNEGSTAPITINRSGDLSIPATILFTTGDGTALASQPDYIGVVQPVTFAPGQASAQVPVQTLFDNLIESNETVNLFLSGGTLASPSAAVLSIVDTTAVPPTFFSYGSSPGAIADGAAGTFTINRTGNTSVSAAIDFLIVAPGGGQPVNNVDFNIAGASALNPNGGSVSFNPGQTSVTLTMNNPVGLTRGVVNLGFGAGPIGAPASTAITLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0R6</accession>
    <name>A0A2G4F0R6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55351">
        <property type="protein sequence ID" value="PHX55351"/>
        <property type="gene ID" value="CP500_011165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="39"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="26027" checksum="313842867DD810E4" modified="2018-01-31" version="1">MTVNLSPFPVSSLKPAAQNVSALKQVFQTIDADSCPGSYNFHLHTINSDGRSQSEQVIEQAIAIGLKGLAITDHHSTKGYAQAQIWLDNWKLNHPDNNSTAPTLWTGAEINAELLNNEVHILGYAFDPEHPSLRPYLRGKSTEGSDNYPAARVIKSIQEAGGLAVLAHPCRYRSTADQLIPEAARFGIDGVETYYAYTNPNPWKASPKQTVLVKELAETHGLLGTCGTDSHGLSLLVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0W0</accession>
    <name>A0A2G4F0W0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55386">
        <property type="protein sequence ID" value="PHX55386"/>
        <property type="gene ID" value="CP500_010960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="782"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="782"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1017"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1651" mass="178557" checksum="D38D7E04411E6975" modified="2018-01-31" version="1">MAMGRRANLPVAGFVLPTVTMVLLVVILLTIAITLRSFDRANTARNVRVNQQVLAAATPAIDRAKAKIQFMLWEDPQRPTGTPSDTELYARMANAAGATDLYSFGDEERLVLRADLSIPKNGISNTDNPKNPPIDPATGVENEALNTAWRYPVDTNNDGFFDTFTLYGIFFRTPKRSDVQDSTLGNFTRARKSLEARTPPTSANSINPECVQGGGTVASLVGDSGWYRVDGPLKKSFFVDTVNVPIKQEDIANLSDPSKYKPFTGTASTSALEYQQDQSRIPLANNAVVYEDDLDISPGPLFNLNGRIFTNSNLLVTNLNGADRTRLYQVSSPDSCFYEQENSKIVVAGNVVNGWSGNTNPAQIKAVGVHLFKKASSLTGNRNAAMLSAAKTIDTAPGNQSSTQTSLEVLYNNEAYADRLSALVAAQMGPLLPPTNKADPNPQPSDPFSVQNKPTSQTRKQALKEYFKQMLRKVPFKEVPLKGDATSTGTPPFIKESNDTLRPNVDTWSTSDATIPISLTLNQLETTTPTADGSPLPEELLLGDRVIAGNNLPAKRWDATKSEFTSKPDQIPGQWNSTDTSGIPRTRSPQVTKLAEVGATDRSGFWEEKAAEVPKNILDGIGGLRVITSAGVYERTNSFLPPPTWINPLTGATLTGDTATYDDPTTTVEEKFPVVWPDSMPMSPVLGVQRVYNNDATDTVAPANGWATNPLPASSASLPAGSSSLIDPNTPKYAKGDLRMRATAVYHYANNPPAKGELNEKPMACVSSYYDPSTASTARNLSTLPDVSGQNATLNPPELGTRGTEVGSNNGVVYGPPADRTEDAQATKGADGLLGGASTTDLLQIQANYVFPDGRFANEPLRTALLTAPGDRKLADKAAIDSTMCALKILAAPTTVSPIIPHGAIQEVAFLNAREVKAIDRDDPTTIVNEAFTLSSPLTTIGTAKPANLTGYYNQPIEEREPLEIRSTQIDLDKLRSNSIAGEPLLPYSGIIYASRDDALPDRSNKDSDEEKSAEVSPTDSLLDPTRKPNGILLVNGSRLARTPSLPPTVANVVMEKGLTLVSNLPVYIKGQFNLHTQQEFKTAFDWSTFYDRPATDLNKNFACRPNDPRLNGQCPTGDEWRPANVLADAITLLSQSYRFGFRNEGDFDLRNNAGAAAVLPRRQQGFYNNNFVTNGFSSGAFLANGNLKAQTDPITVTDASYVDTTTQPLWSSYFNNFITPVQRRGPFPEYVMEVCTKLPVSACTDSDWYVNPALATDPPTEAGKAKVNDNYTAATYPAGTTEIPPTPELQRFPRRVAFERNNTTFALISPADPKPLGIDEGTIKAGVHRIGTNALWFAAKSGVEVAYDATNLPYLVNTSTTTDGTTDGSKVPLPTLDAASTPLPLPAVTVPPAVYSYKGSQPLLVPVPQLRNVKKAIPGTPESIPNVDNVVNGIPGTKDNESAWIPLAVETTFNLIVGANDTPSRTLNATSGDFNGGLQNLPRFLELWRRGATSISNNIQGSFIQLNRSAFNTAPYRSTLPSDYPTGAADKRTTLFAQSTAPTTAATALAGIDTEITQYRISGDPKDGQVPYFTPPTRKWGYDVGLLSQPPDLFTQKFTTPPSKRTPDEYFREIPRNDDWVTTLMCSTLEKDKKNATETLTTTERAKCST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F132</accession>
    <name>A0A2G4F132_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Quinolinate synthase</fullName>
            <ecNumber evidence="2 9">2.5.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nadA</name>
        <name evidence="10" type="ORF">CP500_010615</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>dihydroxyacetone phosphate + iminosuccinate = H(+) + 2 H2O + phosphate + quinolinate</text>
            <dbReference type="Rhea" id="RHEA:25888"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="2.5.1.72"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from iminoaspartate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the quinolinate synthase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.72" evidence="2 9"/>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55470">
        <property type="protein sequence ID" value="PHX55470"/>
        <property type="gene ID" value="CP500_010615"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008987">
        <property type="term" value="F:quinolinate synthetase A activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10800">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00568">
        <property type="entry name" value="NadA_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003473">
        <property type="entry name" value="NadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036094">
        <property type="entry name" value="NadA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023066">
        <property type="entry name" value="Quinolinate_synth_type2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30573">
        <property type="entry name" value="PTHR30573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02445">
        <property type="entry name" value="NadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142754">
        <property type="entry name" value="SSF142754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00550">
        <property type="entry name" value="nadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Iminoaspartate binding" evidence="9">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Iminoaspartate binding" evidence="9">
        <location>
            <begin position="211"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="322" mass="35840" checksum="93E006E356AADBBB" modified="2018-01-31" version="1">MFTTITSPNLTETRLPDDLFAAINALKQELNAVILAHYYQDSDIQDIADFIGDSLELARKAANTNADVIVFAGVHFMAETAKILNPHKLVLLPDLNAGCSLAESCPPEAFAAFKADRPGHLVISYINCTAEIKAMSDIICTSSNAVKIVNQIPENQPIIFAPDRNLGRYVMEQSGRHMELWQGACIVHENFSEKKIVQLKIENPEAEIIAHPECEPPVLRHANYIGSTSALLKYSEASDRQAFIVATEPGIIHQMQKQSPHKHFIPAPPNNNSCACNECPYMRLNTLEKLYLAMKNQTPEITMPEHLRIAALKPIQRMLEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1A1</accession>
    <name>A0A2G4F1A1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55554">
        <property type="protein sequence ID" value="PHX55554"/>
        <property type="gene ID" value="CP500_010230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7833" checksum="87DAE9BEC1FCDBAB" modified="2018-01-31" version="1">MPETKDTSLFTEITAQESASVNGAHRYRDISSRSNCNNYSYSPYFDGRPTYGYIQNVSYRRYYYYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1F6</accession>
    <name>A0A2G4F1F6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55297">
        <property type="protein sequence ID" value="PHX55297"/>
        <property type="gene ID" value="CP500_011680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016780">
        <property type="entry name" value="UCP020893"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020893">
        <property type="entry name" value="UCP020893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="180" mass="19532" checksum="9204385D5A27CC0C" modified="2018-01-31" version="1">MSIPSSLLASENITFEAAIALTQSLLTEIEADRLSQAQIEQAVVSLVKTHNGARGFFVTYLTDDRPLADKPSPGVLDALRDAPAIVAELLVKNLAMSAAMVVHHSRHEKSEMAAGSARVQARSRHLIQTLQMPACQTLAKQMLEDLQTGQGEYEVFFQRWGYDGEQKDAIGSAVRGAIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1K7</accession>
    <name>A0A2G4F1K7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55654">
        <property type="protein sequence ID" value="PHX55654"/>
        <property type="gene ID" value="CP500_009590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="309" mass="33275" checksum="B5C19CB2110117C4" modified="2018-01-31" version="1">MVFATTEMDSSQPESTFDLSTYLVEQKKAIEIALDSALPVIYPEKIYEAMRYSLLAGGKRLRPILCLAGCEIVGGTTQMAMPTACALEMIHTMSLIHDDLPAMDNDDYRRGKLTNHKVYGEDIAILAGDGLLTYAFEFIATQTQNVPPHQVLQTIAHLARASGAAGLVGGQVVDLESEGLKDVSLETLNYIHAHKTGALLEACVVCGAILAGASEADLQRLSRFAQNIGLAFQIIDDILDITATAEELGKTAGKDVQAGKVTYPSLWGIEESKRQAKQLVADAQAQLAVFGNKAQPLLAIADYITSRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1U8</accession>
    <name>A0A2G4F1U8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55722">
        <property type="protein sequence ID" value="PHX55722"/>
        <property type="gene ID" value="CP500_009380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="113"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="265" mass="29650" checksum="91FF15B8F8199EE4" modified="2018-01-31" version="1">MRGIRKQVKKIRIIVKNTRQVIKQLAAIVLAIICLLPLNICAASAGEIATNNNICQRRIIHNPDGIGKFYMGREIAQVMGYQGAGWLERPSRGIEEKSTRLVNNLDLKPTDIVADIGAGTGYFSFRIAPLVPQGKVLAVDVQPEMLKFVELNKIEKNISNVEPVLGTITNPNLPENSVDLVVMVDAYHEFEYPREMMQGIVKALKPGGRTVSIEYRGENPMLPIKGLHKMTQKQVKKEMAAVGLVWKETKEMLPQQHLMVFQKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1W2</accession>
    <name>A0A2G4F1W2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55763">
        <property type="protein sequence ID" value="PHX55763"/>
        <property type="gene ID" value="CP500_009185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="302" mass="34274" checksum="4C1E3FFDA6FB4389" modified="2018-01-31" version="1">MPSSNSRTKIQNPKLTNLSEIAELVFLAASGVGLAASLVFQQSIYAQVPIAISLLLNFVNRQKLQQQLKMSTDSTFDRLNQQTTTTTSAIDQLQIAVKALNQALPQTAHENLNTQPGENVHSLISAVENMRQRLIILEKTLKMIQSEIELTSRQFKQRPELQQVETLTTIILDLQQFINELPQWGNLQQRQLTELQQKVETALGRVSEEIAAIPHRVQEAMGDRNSQPESFVDQKNGDRPKTYDVEIIRQKYPRAYVKWTPGEDEKLKNEYASGQQIGELAKKFQRQSSAIRSRLQKLGLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1X1</accession>
    <name>A0A2G4F1X1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55746">
        <property type="protein sequence ID" value="PHX55746"/>
        <property type="gene ID" value="CP500_009065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15276" checksum="C4EB61BBC90E7639" modified="2018-01-31" version="1">MSISKATPADVEIEAKMQAPHYDRGITPAETAARQEREGANFMHTATEESQKSATTNDQSDDESIRTTDGYTVDKEGLINNYAIEPEMYINEPGDLKEQQEAEAQERARVLVEIKDKRGEEGKLTTEADTRGKGPGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F266</accession>
    <name>A0A2G4F266_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dihydrobiliverdin:ferredoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HY2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55864">
        <property type="protein sequence ID" value="PHX55864"/>
        <property type="gene ID" value="CP500_008505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016636">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010024">
        <property type="term" value="P:phytochromobilin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009249">
        <property type="entry name" value="Ferredoxin-dep_bilin_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34557">
        <property type="entry name" value="PTHR34557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05996">
        <property type="entry name" value="Fe_bilin_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="244" mass="28368" checksum="A526A96014F3306D" modified="2018-01-31" version="1">MFKPFQQFLEKELSENFALESRPIPSGLESVVSERGKNPATIQSWCYQCPQLRKIRYTYIDAGETAQIFNSVIYPNYNYDVPLLGIDFLAFGKKKILVVIDFQPLFRDRTYIDKYIEPLTEIRSKYSALVQDLEMKFYDANQYFSKNLLFAKTDAETVVNQLFPAYQEYVQLYCKMLQQASPLNTPAEVQRIVKAQKDYDQYSAERDPASGLFSSYFGHEWSEKFLYEFLFEDAVPLAIPAGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2A6</accession>
    <name>A0A2G4F2A6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55904">
        <property type="protein sequence ID" value="PHX55904"/>
        <property type="gene ID" value="CP500_008390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="136" mass="14531" checksum="B21C4B74034B12AE" modified="2018-01-31" version="1">MFGFITNFFGGIFSFFGGLLGFKKSEYFLDLGNSDTNESPKVELAAAKKPEPVVAAPAVAKADSPKKAKAETSQKSQKEKEPVKVAAATNGKVSSSTEPTLTFAPNNLMPIPTASRRTPGPSMNGFRDMARQVKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2M0</accession>
    <name>A0A2G4F2M0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56023">
        <property type="protein sequence ID" value="PHX56023"/>
        <property type="gene ID" value="CP500_007675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8916" checksum="B9F3AEF92D952DB4" modified="2018-01-31" version="1">MDSNTDFRRSNPASTAFYQELGAELIFTQDREGRYLSFYWQQAEHYNLTLEQMVDRPAIDHFQLYEEPLFNQCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Q7</accession>
    <name>A0A2G4F2Q7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56032">
        <property type="protein sequence ID" value="PHX56032"/>
        <property type="gene ID" value="CP500_007720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="166" mass="18361" checksum="122D6F8DE82BCEDA" modified="2018-01-31" version="1">MKTQFYNLIATLGLFTIFGNISPAVSAKSSAILIAQKTIVQNPAEDLFNSGFTKSEAGDIEGAIADYTAAIRLNPNYAKAYNKRGIIKGRDLQDYPAAKADFDRAIAINPNYGDAYYNRARVREFLEDKPGAIADYQKAAELYQKDGNTNDYQDALKHLQILLPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2U1</accession>
    <name>A0A2G4F2U1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55777">
        <property type="protein sequence ID" value="PHX55777"/>
        <property type="gene ID" value="CP500_008995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006120">
        <property type="entry name" value="Resolvase_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02796">
        <property type="entry name" value="HTH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_7" evidence="1">
        <location>
            <begin position="130"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="20329" checksum="4491781459A044AD" modified="2018-01-31" version="1">MNDNIVEVIPGIFGEIQPTGCIISTLSKNSRGYANKRLKIDGEWKTLTIHRLVLENSLGRPIRPEYFCCHSCDVRNCINPNHLWEGCRLENSQDRFRKGRIKDVGSTSAPQPKKELHRFPFVPGKICPSRKLKPEQVQQIRYLLSEGISKREIARTFAISRSQIILLGRGEIYRDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2V9</accession>
    <name>A0A2G4F2V9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EAL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56090">
        <property type="protein sequence ID" value="PHX56090"/>
        <property type="gene ID" value="CP500_007225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="6792" checksum="16160D80C2EE215C" modified="2018-01-31" version="1">MDTPQFIIHYQPIVSIATNKITSFEALVRWQHPERGLVSPSDPPKSPLRRGTLIGLLSPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2X3</accession>
    <name>A0A2G4F2X3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56099">
        <property type="protein sequence ID" value="PHX56099"/>
        <property type="gene ID" value="CP500_007275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="149" mass="16787" checksum="F5BA2C8D8442AF46" modified="2018-01-31" version="1">MSEISAVEIETGENRTGLEPELGGFLRDAPDRTGLEPELGGVFRQKGVYVDEITCIGCKHCAHVARNTFYIEPDYGRSRVVRQDGDSEELIAEAIDTCPVNCIHWVDYTELKNLEKERQDQVIPVVGFPAEYATIRARGRRDRNSKHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2X8</accession>
    <name>A0A2G4F2X8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55817">
        <property type="protein sequence ID" value="PHX55817"/>
        <property type="gene ID" value="CP500_008650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="620"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="784" mass="89056" checksum="81EE152C6F406739" modified="2018-01-31" version="1">MKRIFLVGSPRSGTTILQSLLAAHPEIISFPESKFFHYLLYEEFATKLPSRLETFFRDEINRPEFLHDFDNSQKDENKAAWFVRILDGLAVEENKSIWLEKTPEHIYFIQDIQRLVPDAKFIHILRNGMDTIASLYEATRTFSNLWGGVWDLEHCIERWKDAVLISHKYVNESRHMFVKYEELIDNKNLVLAGICDFIGIEYDAAMLINYKKNAANLSLNLPWHQGITRDVQSTNIHKYHENFNRHQIQSILTQIQWVNSQIAYQFNVEVSQPILDIELPQIFDRTYCTIQLEGVELGIIELPVCDGIVAGVVLADAIASEFAWEIIKRFFQQNPENLPFEWTVFLQQIWNRPNWVSEYFYNPETADESFTINLDRDLIAVEVSAELPNIKVELSEIDVLVKVGGVAIGIITVAVENNLVSAQKVRSAITQNCGFELCVACVREALVGKSLSKEMSLRSRLTSAAQKMANAPKSLNAEGSGGIYPPHAVMFGRREGAIGTSVNRRATLPAAAMRELTEVAAIAGEPISQIPLEKNLPKQVFYAPEIIWRKSPYREISQSLKPQFFDNNNVTENLPILAYNRICTEIFEQHLQNLKDCGYYSVSWEDWQNAKLAKTPLPGKAVLLTFDGGYLDFFNHAFPLLKRFNFTATVFLVAESIGKTNSWEKADSEQVQLMGWREIRQLRDAGIEFGSMSATYQPLTGLSPTEIVREAAKSRAILELGLGKPVKCFAYPYGNVDKIVEHLVGAIGYTYGVSYESKFSNFEDSLLSLPRIQVTTENALLFTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F368</accession>
    <name>A0A2G4F368_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Photosystem I reaction center subunit XII</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">PSI-M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">psaM</name>
        <name evidence="8" type="ORF">CP500_006750</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cellular thylakoid membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PsaM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56202">
        <property type="protein sequence ID" value="PHX56202"/>
        <property type="gene ID" value="CP500_006750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00828">
        <property type="entry name" value="PSI_PsaM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010010">
        <property type="entry name" value="PSI_PsaM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037279">
        <property type="entry name" value="PSI_PsaM_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07465">
        <property type="entry name" value="PsaM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81548">
        <property type="entry name" value="SSF81548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03053">
        <property type="entry name" value="PS_I_psaM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="31" mass="3440" checksum="A31EFB444FD3C504" modified="2018-01-31" version="1">MSLTDSQVYIALVIALIPGILAFRLSTELYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3B7</accession>
    <name>A0A2G4F3B7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56260">
        <property type="protein sequence ID" value="PHX56260"/>
        <property type="gene ID" value="CP500_006230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="16789" checksum="A7070A4976840A07" modified="2018-01-31" version="1">MEDYQAAFIERHFDTEALNQSKRKVAAMHFGGVTIECLLKAMIFASLGKGATQEWKTDSNNPGHTITNPGHSYIEALKRNNRLRSKIDNFPEVRKWLDEVENPTSQHFINMRYSGIEPDDESYKRWLNAYQSLKRWLQKQATQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3I3</accession>
    <name>A0A2G4F3I3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56281">
        <property type="protein sequence ID" value="PHX56281"/>
        <property type="gene ID" value="CP500_006370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="614" mass="67868" checksum="3CF641D0D573F257" modified="2018-01-31" version="1">MSSVLKADVLVVGGGTGGTAAAIQAARCGAKTILVSEFPWLGGMLTSAGVSAPDGNELAAFATGLWGQFLRELQQRQPEGLDWGWVSFFTYDPRIGASIFADWVKCLPNLHWISGHKPQGVIKEADRIVGVQFPDFTVSAQITLDATELGDLLALGEVSHRWGWEFQAEFREPSAPIAPNDLTQTYPVQAPTWVAIMQDFGEGAVAPEIPAPPIHNPDRFTGAWDNYTPEQFLNYGRLPGGLLMINWPICGNDYGEKLDRLIGSETSQQEFLQESLWHSQSFTHFIQTQLGRRYSLAENIFPTSHTKNQQNSAFALHPYYRESRRLQGITTIREQDILPITGGRVAKLPINTEGICEAVAIGNYANDHHYPSGDISLQPKSIRWGGRWTGTPFTIPYSALIPVSTDGLLVCEKNISVSHIANGATRLQPTVMNIGQAAGMAAALCVQRECQPRDLPVRLLQEALLQDSQASAKVIPLFNLTPDRSDWLDWQCYYLDRPSSYPASGNCPLSVDKHRSILLGTSQCRVPTLDRAQSPFSGIFHRLGEQDYALTLTEPLSLAAQTWKLVTLDPETDKFLLSYETQKPLTVWGKLNFAGAWLLVFRVELKESGFLQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3S5</accession>
    <name>A0A2G4F3S5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56385">
        <property type="protein sequence ID" value="PHX56385"/>
        <property type="gene ID" value="CP500_005580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="43"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="303" mass="33345" checksum="7ED096C63A03FCD9" modified="2018-01-31" version="1">MLLPLGFGQRSTVTSLGRMVYYTAEKMPWMNLPTSSSDNLPNLLFLHGFGGGSSAYEWSKVYPAFAADYRVLAPDLVGWGRSEHPPRNYQVDDYITTVIEFIEKTCGSATDVIASSLTGAIAIRAAIVRPDLFKSLILTTPSGLSDFGTDYSKSLFAQIVSTPILDRLLYSTGIATDGGIRNFLEQRQFADARRVYQEIVDAYLESALEPNAEYAALSFVRGDLSFDLSLYITQLTTPTAIIWGEKSQFTNPDIGKRLANLNSEAIKVFQPLENVGLTPHLEMPAVTIGLIRQYLNLLSDGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3T5</accession>
    <name>A0A2G4F3T5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cadmium-translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cadA</name>
        <name evidence="8" type="ORF">CP500_005715</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56409">
        <property type="protein sequence ID" value="PHX56409"/>
        <property type="gene ID" value="CP500_005715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00941">
        <property type="entry name" value="CDATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="617"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="661" mass="70868" checksum="9DEA5DABE5303A41" modified="2018-01-31" version="1">MQKAKSSDSGCCSHDDHDRSHENHNHDHDHGHDHDHGNGDFNLKQELVPVILVVVLFVGGLIFEEKLHNTPYSIGEYLVFIPAYLLSGWNVLTSAGRNILRGRVFDENFLMTIATLGALAIHKLPEAVGVMLFFKIGELFQDFAIGRSRQSIRSLLEIRPDSANLKQNGDIKKVAPETVAVGDIILVKPGEKIPLDGEIIDGNSQIDTSALTGESVPRTVKVGETVLAGTINQTGVLTVKVTKVFGESSISRILELVENARSKKAATEKFITKFANYYTPFVVFASLAVALIPPLFISGVTNADRFLWVYRALVLLVISCPCGLVISIPLGYFGGIGGAAKGGILVKGSTFLDTLTAVKIVVLDKTGTLTKGVFKVAQIVPANGFSQTELMEIAAKIESQSNHPVAKSIVEAYGGKIDSSDVKDYEEIGGHGIRAKVNNQIVIAGNDRLLHRENIPHDVCNAGGTVVHLAVDNRYAGHILIADELKEDAVQAIRDLKKLGVERIVMLTGDNQAVADSVAKKLGLDSYLAELLPEGKVEAIEKLISQSKKGDKIVFVGDGINDAPVLARADVGIAMGGLGSDAAIETADVVIMSDAPSKVAEAIQIARKTHNIVWQNIIFAMSVKGIFIALGAFGLATMWEAVFADVGVALAAIFNATRVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F445</accession>
    <name>A0A2G4F445_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56532">
        <property type="protein sequence ID" value="PHX56532"/>
        <property type="gene ID" value="CP500_005050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="12341" checksum="90B232E73CA9BC76" modified="2018-01-31" version="1">MTTSNHSHYFQDIRHLHRILAPIMLLPLLLTTITGTVYQVVDLAGQEKAFKWLLHWHKGHFGALNLEVIYPFLNALGLFLLLFTGISMWQRSQHSSKKQSTEVKSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4H5</accession>
    <name>A0A2G4F4H5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56660">
        <property type="protein sequence ID" value="PHX56660"/>
        <property type="gene ID" value="CP500_004355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="87" mass="9813" checksum="9B409B67BF095389" modified="2018-01-31" version="1">MYSSEQKQTIVEAAKEIQQLLKQLEKMNPNPTEVEKIEYVNDETTPSFKRRVVAALQAGGEAAIEEFLDNAYVNVGKAIVKGWMKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4J6</accession>
    <name>A0A2G4F4J6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2949 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56703">
        <property type="protein sequence ID" value="PHX56703"/>
        <property type="gene ID" value="CP500_004065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021336">
        <property type="entry name" value="DUF2949"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11165">
        <property type="entry name" value="DUF2949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="8226" checksum="783435DBFFF56830" modified="2018-01-31" version="1">MAPGTYTKLIRFLQEDLAISRASIDVAERVGANERQQRDRDPNSLPMVLWQYGLVTLEQLDKIFDWLAQAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4M2</accession>
    <name>A0A2G4F4M2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56696">
        <property type="protein sequence ID" value="PHX56696"/>
        <property type="gene ID" value="CP500_004185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17916" checksum="D9CC9E7B5C2EC0D0" modified="2018-01-31" version="1">MANLKPQKEKLSSKIPAGVSGLRQAFHSHLSAYEKTKDTFSTSSYLLLFYAAECGMKRIWLIRNNLRTTNDISDPTLLSRDGHNLDRWKKELRISASIVGDTPHFSLASDGSDLGIEKAHQLWRYGIRMDSDKEKRVVEWLEKVCHWVKKEDRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F531</accession>
    <name>A0A2G4F531_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2470 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56821">
        <property type="protein sequence ID" value="PHX56821"/>
        <property type="gene ID" value="CP500_003210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019595">
        <property type="entry name" value="DUF2470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037119">
        <property type="entry name" value="Haem_oxidase_HugZ-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10615">
        <property type="entry name" value="DUF2470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2470" evidence="1">
        <location>
            <begin position="10"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="94" mass="10385" checksum="0B5E881CDB33A94D" modified="2018-01-31" version="1">MSEPFSIEISDRICTHMNEDHASAVVLYAQAFGDKPDATSAQMLAIDANGMDLTAQVNGETLPVRVKFERTLKDAEDAHHTLIEMLKQARKVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5C0</accession>
    <name>A0A2G4F5C0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-alanyl-D-alanine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX57003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57003">
        <property type="protein sequence ID" value="PHX57003"/>
        <property type="gene ID" value="CP500_002370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000667">
        <property type="entry name" value="Peptidase_S13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30023">
        <property type="entry name" value="PTHR30023"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02113">
        <property type="entry name" value="Peptidase_S13"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00922">
        <property type="entry name" value="DADACBPTASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013915331" evidence="3">
        <location>
            <begin position="22"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="438" mass="46915" checksum="EA757FA148A29481" modified="2018-01-31" version="1">MLKMRYLKPIALLTLITGCAATPSAELSSSTPVATVSPSPIQVNQPLIVSVSNPETTTNTKIQQYLNSLTSQGFAKENQGIWIQSGNTLLANHQGTIPLPAASITKVATSLVALQKFGPEHQFITLISTNGRIENGILKGDLIIQGGEDPLFVWEEAIAIGNALNKKGIKRVTGNLIIVDKFYMNFELNPLKSGELLKEGLNSQIWSAEATAQHQTLPPNTPKPQVTIDGTVKVSSTPTISAQPLIKHYSLPLAELIKKMNQYSNNLMADMLADTVGGAKVVAQQAAAATGLPPAEIQLVNGSGLSEENLISPRAACGLFLALERYLQPYNMTVADVLTVVGKDKGILSERPLPKLAVIKSGTLDNVSALGGALPTQKQQTVWFVMMNGGPNVEVFRTQQEVLLKDFLSEWGAVQASPPELTANPARNSKVSRSEIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5C1</accession>
    <name>A0A2G4F5C1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56939">
        <property type="protein sequence ID" value="PHX56939"/>
        <property type="gene ID" value="CP500_002880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="6"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="425" mass="44838" checksum="953BA6F23C7146C4" modified="2018-01-31" version="1">MGDIDQYYQILEIEPGASLEEVKQAYRDLVFVWHPDRFVHNDRLQQKAQQRLTEINEAYQQLLLFLSQPELKAIEPQFGPPTPPVPIRENLNRKGFRKPAGRSGSQKSQNYRKATSNSQKGFKTQNRETFLGKRSNLKTPNHAKPTSKRKKQFSTQYSKPRNFATETRQSQKYSSFPWWSLAIALASYALTGWILTKSAAPLWMWTLICGADGLWAAILVAEGSATPRVWLAALALAGTVGGAIAGFQAGGVVTGMVWALVGAGLGAIASSEAESRAVAGVVAIAGVATVTGLMAGTGSGDWVRTVAGGICWGAVGLICGLMAEVGVNSQGPRGLAGLIGLGIGAGVGAVAVAGSGALTQALAIAGSKTVYGAWAAIGIIAGVVARMVVAERSIGSGKGFYTSILLVATSGFGLWLGNWLGDRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5G8</accession>
    <name>A0A2G4F5G8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56989">
        <property type="protein sequence ID" value="PHX56989"/>
        <property type="gene ID" value="CP500_002570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="324" mass="36455" checksum="D24A43B1BC485938" modified="2018-01-31" version="1">MNRRFPDGQNLGKNNWGNKVMLKLDSKRSRYIGMDWQSKQHLFTIAPNDSLICCDLRGCIFDKLDLSGCEFFGCRLNGTSFQRATLYETKFIGCFSDEADRPTDFSNAIGTDLSVESSHINFLSEEHQPNFSNSFWGDDLILGDSIPDVMKWPSEVAKAAADTLSERNDVRYNATVKLGELDNPVVAPLLGCLLADKEWDVRAIALEVLGKLRHQKFWYGDEVLLEWMFLCLGDRHSIVRQTAVELVETISPPERVLLTSINRMVVGASDEERLAGVLAAIELCQLNDDYVDLCDREVIDSILLEAGSEVSSESSRLLEIIGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5I5</accession>
    <name>A0A2G4F5I5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57032">
        <property type="protein sequence ID" value="PHX57032"/>
        <property type="gene ID" value="CP500_002265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="149" mass="16783" checksum="FE6AD9184652A92B" modified="2018-01-31" version="1">MSEEESQSEKQPYPKKAEDLESGDLEGISSELENLPPEVKRFMQATLSMQRISTPLVSPILEKVNENHISKILEIAEKEDERLFADTESARKYTLINTILILGFFGFLTVFLVNKDIAVYQEILKIIIIFGGGLGSGFGLKGYLDRKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5K9</accession>
    <name>A0A2G4F5K9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_002155</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57050">
        <property type="protein sequence ID" value="PHX57050"/>
        <property type="gene ID" value="CP500_002155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="574"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="5">
        <location>
            <begin position="95"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="6">
        <location>
            <begin position="297"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="141"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="291"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="651" mass="70168" checksum="93F8D2A6A9B008E4" modified="2018-01-31" version="1">MIFHKSAQFAAIISSGYGTLLSLILLTSPTAVFAHAGHGDEFHQSGETTQIPAAISVDAETSKRIGIKVEPVRAQRLAVGIKTTGQIETLPNQKVEVRAPVSGTVVELLVKPGDKVSKGQTLAVLSSSELGQLRVESVSKRAEAEGNLQQAQADFKLAQENYDRQLQISAAEIAQAKTQLTAVTQQYEQEQQLVNNRSVVKVAKENYQRQVEISQAEIARAETELTVAKEQFDRDQELVASGAIARRTMLESQAHFAEAKATVAKAKSRPEVVKAETEIRQAEVDLPLRELRDSQGKVAEAKAQLTKALSRREVLEAEAQLKRAKAALEVAQSRIRLSSSAYEARLQQLGIAANDKGLVTVVAPIAGTVADREITPGESVNSAEKPLMSILNDSSVFATANIYEKDLNLVKNGQELTVKIASLPNRTFRGKISFIGSIVEGETRAVPVKALLDNPERILKPGMFAELEIFTDKTATNILAIPVSAVVEASGKQLVYVKNGDAFQAMEVALGQSSGDLVEIKSGLFEGDLIVTQRAPQLYAQSLRGGSKQSKTEDKKEVTPKATEASFNSSPVPLWAGIGGGMAIASLTFAIGALWGNRRKFPAVAASQSHASNGFSISAPMLNDELVLHNVHNDNHHVKVKEAEIEKVNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5L2</accession>
    <name>A0A2G4F5L2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56767">
        <property type="protein sequence ID" value="PHX56767"/>
        <property type="gene ID" value="CP500_003935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8253" checksum="49737090578A04C2" modified="2018-01-31" version="1">MNVDFIKAQVRLLQGASSSERETLMKNIGVCAGVIRPGEYVTPQRKHAITIWLQTNAVRLRLPQLPLDLSGHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5R9</accession>
    <name>A0A2G4F5R9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56827">
        <property type="protein sequence ID" value="PHX56827"/>
        <property type="gene ID" value="CP500_003250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="538" mass="62590" checksum="F59BB466F5033524" modified="2018-01-31" version="1">MSKSSNQENIPTLPKRLNNSDIFCTYLTLNTDNSRKYFQWNNALHLNRNFELYARNNEVFAQFCSQPNGITNILEFWKTIAIDASPILQEWERQNSKQLALHHLMSYLETSCYYATKKVSSISKISSWEDYLSSARIFIHNSDNLVKLLKSYDDSQALLDTYIQGILIKEIQNQQNIGKFSPWRMLGKTSEKLLREALQRSGHKEPYISQYIFARKHFQPVYNFNKVRNPLLRKSGDKWLEPDSEDFQAAANCYNAEKFLSSAPHEVSAGSNISTEQMQAWMKICISSIQEYDQIKQDSERCLDDSQPEDINFEAEESDSESNSQFEETQSAFHKELDRFKPDQHQILLLYYGANLKQKQLKIKLGVSQSAICRRLLTIKNQLLKTLIQKSQPHEWVRNYVVEWLHKDFCAPRHSDLIEAALVQATKELGSEEQQILFLRYGEKVNEQNIATHFGISLFEVNAIIAVSQHKLQAHLIKELPHWEKECVEEWLKSFYHSKISAACRTLNLSLEMDDSHQIIDKIVEECLQNLIVTEKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5T4</accession>
    <name>A0A2G4F5T4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rplB</name>
        <name evidence="4" type="synonym">rpl2</name>
        <name evidence="7" type="ORF">CP500_001800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57153">
        <property type="protein sequence ID" value="PHX57153"/>
        <property type="gene ID" value="CP500_001800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="124"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="208"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="287" mass="31414" checksum="961E36E607EFBA17" modified="2018-01-31" version="1">MGIRSYRPYTASTREKSVSDFAEVTRSEPEKSLTSNKHTKQGRNNRGVITCRHRGGGHKRLYRDIDFRRDKHSIPATVKEIEYDPNRNARIALVFYKDGEKRYILHPLNLTVGTVIVSGPDAPIEIGNALPLSNIPLGTSIHNVELVPGKGGQIVRSAGSSAQLMAKEGSYVTLKLPSGEQRKVRADCYATIGQVGNTDARNISLGKAGRTRWKGRRPTVRGSAMNPVDHPHGGGEGRAPIGRSGPVTPWGKPALGAKTRSKNKRSDSLIVRRRRKSSKRGKGGRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5W6</accession>
    <name>A0A2G4F5W6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GHL10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_001560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57115">
        <property type="protein sequence ID" value="PHX57115"/>
        <property type="gene ID" value="CP500_001560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003790">
        <property type="entry name" value="GHL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02638">
        <property type="entry name" value="GHL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="GHL10" evidence="5">
        <location>
            <begin position="442"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="261"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="261"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="304"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="920" mass="101217" checksum="2521CE06726FAEDE" modified="2018-01-31" version="1">MQQIKKPHPISDVCSQAQKIRFFTFLQRVLIGTLASSLLNLFILFPSPSFAEVVLGVVRISENSPDWQKITTRLGESGIPYKPINIEEIKSVGDLAGFNTLFLPNIETLSPAQIKVLQAWASQGGRLIASGPVGRTSPALVRQSLRSLLGAYWAFPLTQPAAPQPRTRCRDLACTTSSNWVPAEQKNSSVQGGVLIPADANSQTVATWKDSSGSSAAIATDRTTYLGWRWGSDGSAKVDTAWLRASIARWGGTVAVPIPPQTAIAPPIPPSSRLPRNTPPAPRNTPLSRLSPSPPLPDPVPATFTDPSDQSAPAGLDVQANSNKPIVSIEAYLMRQELTNLLGRFESALTAANSANTPVNLNAANTAQLVAGSNSGGAPAASRPPTIQGATTRTIAIARQALQSFDQLLQEQNYAAARKQWVEARQLLWQNYPKEGQRVGAEIRAVWLDRGTIVAARSEQGLAAVFDRLAAAGINTVFFETLNAGYPIYPSQIAPQQNPLTVGWDPLQSAVKLSHERGMELHAWIWVFATGNKRHNTLIGQPSSYPGPVLSAHPDWANIDNKGRRQNPNDGKFYLDPANKEARSYLLRIVDEIASRYKVDGLQLDYIRYPFQDDNAGFTYGYGVAARQQFQQLTGTDPVKFSPSDGNLWRQWVEFKTNQINTFVGEVSQLLRRNYPRTILSVAVFPHPPSQRIYKIQQNWEVWARQGIVDLIVPMTYALDTNRLQRITEPLAKEQMLGSALIAPSVKLLTLPEVVAIDQIQALRDLPTGGYAIFAVESINSAMQGFFNRTQGARVRSASALEPIPYRQPFAAAASRYNAMKQEWSFLLASNQLRVSESELKVLQSRSAELAIALSKLAASPTTENLTIAKRLLASFQSQFQSSMRLHSTENSYQVQTWQNRLDSLEMLLRYGERVELNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F671</accession>
    <name>A0A2G4F671_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Photosystem II manganese-stabilizing polypeptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_001320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PsbO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57191">
        <property type="protein sequence ID" value="PHX57191"/>
        <property type="gene ID" value="CP500_001320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010242">
        <property type="term" value="F:oxygen evolving activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042549">
        <property type="term" value="P:photosystem II stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002628">
        <property type="entry name" value="PSII_MSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34058">
        <property type="entry name" value="PTHR34058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01716">
        <property type="entry name" value="MSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013747280" description="Photosystem II manganese-stabilizing polypeptide" evidence="5">
        <location>
            <begin position="21"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="279" mass="29691" checksum="B7B208FA941A9A9B" modified="2018-01-31" version="1">MKYRALIVTLLAFCMSVLVACSSASDTVATTELLTYDQIRGTGLANNCPSLAETSRGSIAVEAGGTYKLTGLCLQPTTYFVKEEPTNRRQEAEFVPGKLLTRFTSSIDQVQGTLKVGTDGTLTFTEEDGLDFQAITIQLPGGEQVPFLFTIKELVASSDPGVVAINTSTDLKGNFNVPSYRSAGFLDPKGRGVATGYDNAVALPATDNSKLKRSNVKLADTRTKAGKISLQVAKVDNSTGEVAGIFESTQPSDTDLGARPALDVKIRGIFYARIEPSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6A9</accession>
    <name>A0A2G4F6A9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">16S rRNA (Guanine(966)-N(2))-methyltransferase RsmD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rsmD</name>
        <name evidence="3" type="ORF">CP500_001030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57255">
        <property type="protein sequence ID" value="PHX57255"/>
        <property type="gene ID" value="CP500_001030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="185" mass="20285" checksum="DC8CA13B8B8F7CEB" modified="2018-01-31" version="1">MSLRICGNRQIKTLPGLETRPTPSRVREALFNIWQGTIANCRWLDICTGSGSMGAEALCRQAASVTGIEQSAKACAIIQQNWEQVANSSQEFQILRGSAIAKLASLSTQQFDRIYFDPPYASDLYEPVLNAIASQEMLAPNGEIAIEHSCGRSAQPIVGLEICRQKVYGNTALTFYTSCSDTHHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6C2</accession>
    <name>A0A2G4F6C2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamine synthetase I beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57037">
        <property type="protein sequence ID" value="PHX57037"/>
        <property type="gene ID" value="CP500_002290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040577">
        <property type="entry name" value="Gln-synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022147">
        <property type="entry name" value="GSIII_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18318">
        <property type="entry name" value="Gln-synt_C-ter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12437">
        <property type="entry name" value="GSIII_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="3">
        <location>
            <begin position="192"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="724" mass="79007" checksum="CCF12296C9C89962" modified="2018-01-31" version="1">MSGNESRVQAISQIVNRKLMPARPPKRLEDMWATDVFSLSKMQESLPKSIFKSVKNTVQTGKKLDESVADVVAVAMKDWAISKGALYYAHVFYPLTNSTAEKHDGFISVQSDGSAISEFAGKVLVQGEPDGSSFPNGGIRSTAAARGYTAWDVTSPAYVMETDNGMTLCIPTVFISWTGEALDKKTPLLRSIAAMNKAATRVLKVLGNTEVAPVNSSCGAEQEYFLIDSNFANNRPDLMLAGRTLFGKPPAKGQQFDDHYFGAIPERVQVFMQEVEERMYRLGIPAKTRHNEVAPGQFEIAPFFEAANVASDHQQLTMTILRNTAKKHGFVCLLHEKPFAGINGSGKHVNWSVGNATQGNLLDPGDTPHSNVQFLVFCGAVIRGVHKYGPLLRAVVATASNDHRLGANEAPPAIISVYLGSQLENIFEQISQGGVKDSQGRGIMNLGVETLPTFVKDAGDRNRTSPFAFTGNRFEFRAVGSGQSVSGPLVAMNTILADSLDWVANKLESDLATGTELNAAIQTVLKEVMDEHGAVVFGGNGYSEEWHKMAVEERGLANLRTTADALPVLKEGYIEDLFEKTGVLTPVELESRYDVYAEQYLLAIEVEAKLVVSMAKTMIYPAGVSYLSDLSKTIAGLKEIGIELDKATAEKVATLVKSMMDCASKLSDALSKHDFASTEEHMQYASQTIRPLMDEVRQYADGLEGEIADDLWPLPTYQEMLFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6D9</accession>
    <name>A0A2G4F6D9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57261">
        <property type="protein sequence ID" value="PHX57261"/>
        <property type="gene ID" value="CP500_001070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016676">
        <property type="entry name" value="P_lipid/glycerol_AcTrfase_prd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016753">
        <property type="entry name" value="P_lipid/glycerol_ac_tran_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="284" mass="32572" checksum="D142F6ED92247507" modified="2018-01-31" version="1">MKYSASSPISNSKTSRFDGLSLDDRNPEFIQLMLPLWEWLYRYYFRVESDGWQHIPASGKMLFVGSHNGGIVAPDMFMFLYEWFHRYGTERLAYGLMHPTVWKVSPELASMAVQCGAIKAHPKMAIAALRKDYPVLVYPGGAEDTFRPHHLRDKIYFAGRKGFIKLALREEVPIVPIISHGAHDTLMVLGDFYQEVKQLHEWGMPWLFGIDPVVFPVYLGLPWGLSIGPLPHLPLPMQIRTRVCKPIVFEKYGSEAARDRDYVDACFDLVTNQMQEELDYLIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6I2</accession>
    <name>A0A2G4F6I2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57097">
        <property type="protein sequence ID" value="PHX57097"/>
        <property type="gene ID" value="CP500_001885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="39"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="300" mass="33606" checksum="7ABA832CDE7B962F" modified="2018-01-31" version="1">MQTTPAMTAAPIPGTYWQWRGHSVYYVRSSSPHPDRPPLLLIHGFGASTDHWRKNISALSQDFEVWAIDLLGFGRSAKPEMQYSGDLWRDQLHDFITNVIGRPAVLAGNSLGGYAALCVAAQRPESAAGLILINSAGPFSEPQPAPEAPPLQKAISAVAKALFQQDWASFLLFQYVRQRSTIRKTLEKVYLDQSAVTDQLVEEIYQPSCDRGAPKVFASVFRTPQGEKIDILLSQLTCRLLMLWGSGDPWMNSTDRSAKFRKHYPQLTEHFIKAGHCPHDEVPEQINELIRGWVIDHICI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6M6</accession>
    <name>A0A2G4F6M6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3318 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57408">
        <property type="protein sequence ID" value="PHX57408"/>
        <property type="gene ID" value="CP500_000260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021751">
        <property type="entry name" value="DUF3318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11780">
        <property type="entry name" value="DUF3318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="222" mass="24923" checksum="91EE633BEE1A20AC" modified="2018-01-31" version="1">MTSYATSTARAEMSEIRRLKNILPPELQSWVTVEKTIEVNPPLIRSEEIGKDQVEVQIDLIRWEQLAMDQRNLLFWHEVARIQNDTIPRDGWEMAALAIGLGGAVGELWVQDGLLLVLALSLCGVSGWRLYRKNNGEKSLKEAIDADEKALALATRFGYTLPNAYKSLGSALKTLIEQTSKKQQRAKYEARLQALKRNAAKAKAKVKPIGRETSQSENVYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6M9</accession>
    <name>A0A2G4F6M9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57410">
        <property type="protein sequence ID" value="PHX57410"/>
        <property type="gene ID" value="CP500_000270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10941">
        <property type="entry name" value="CE4_PuuE_HpPgdA_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045235">
        <property type="entry name" value="CE4_PuuE_HpPgdA-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022560">
        <property type="entry name" value="DUF3473"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11959">
        <property type="entry name" value="DUF3473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3473" evidence="2">
        <location>
            <begin position="131"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="260" mass="30214" checksum="92255FDC41F86855" modified="2018-01-31" version="1">MNKYILLSFDIEEFDIPEEYGQPLENDIKFAVSQKGLLNVISLLDRLEITATFFVTANFALHNREIIKQLSQQHEIASHGFYHSQFSPDDLLKSKETLESITNTKVTGFRMARLQPIDDAEIEKAGYEYNSSMNPTYIPGRYNNLSKPRTAYYTNKLLNLPISVTPLIRFPLFWLSFKNFPLSMIQLATKLTLETDSYLNIYFHPWEFTDISQFKLPAYVKKNSGSKMIDKLEKYLTVLKNQGRFISISEFKKNFSSKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6P1</accession>
    <name>A0A2G4F6P1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">der</name>
        <name evidence="11" type="ORF">CP500_000370</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57426">
        <property type="protein sequence ID" value="PHX57426"/>
        <property type="gene ID" value="CP500_000370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTP-bd_EngA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="4"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="176"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="57"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="120"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="182"/>
            <end position="189"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="229"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="294"/>
            <end position="297"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX57426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="454" mass="50693" checksum="5A6D9899EFDA5004" modified="2018-01-31" version="1">MPLPIVAIIGRPNVGKSTIVNRLANCQDAIVHDEPGITRDRTYRPAYWGDREYQVVDTGGLVFDDETEFLPMIREQAMAALAEASAAIFVVDGKVGLTGGDEAIASWLRLQRVPVVLAVNKCESEITGLTQAADFWQLGLGEPFPVSGIHGNGTGELLDQLITHLPTEVLPEVEETKVAIIGRPNVGKSSLLNAFLGENRAIVSPISGTTRDAIDTIVQRGDNTYRLIDTAGIRKKKNVEYGAEFFGINRAFKAIRRADVVLLVIDAIDGVTDQDQKLADRISQEGRACIIVVNKWDAVEDKESDTIYEYEKEARSRLYFLDWAEMIFVSAVTGQRVEKTIELIDKASSEHKRRVATAVINEVIEEATSWHSAPVTRQGKQGKIYYGTQVRSEPPTIALFVNDPKRFTENYRRYMESQFRKHLGFTGTPMRLLWRGKKVRESEQSSTNRALRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6R5</accession>
    <name>A0A2G4F6R5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4349 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57448">
        <property type="protein sequence ID" value="PHX57448"/>
        <property type="gene ID" value="CP500_000110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025645">
        <property type="entry name" value="DUF4349"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14257">
        <property type="entry name" value="DUF4349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="324" mass="34988" checksum="9031A9D4E4AB30F8" modified="2018-01-31" version="1">MENGARSQFNPISANNSATRFAIVAFLTLSSTIALPSCGAPPTSQRNQMAAGAPQASPAPASEAIRGEAADSKMAAAPKQAKAETTATRPQLIKKAELSVVVKSIDVSTKSVTNIVEKQQGDILGFQNQKPPDSSIRQTATMEIRVPQERLETTLDTLAKLGTVENRGLTAEDVTTQLVDSEARLRNLRKSEEMVLKIMDKSGSVGDVLKAAKELSNIRESIEQIDAQLKSLRNQVAYSTISLTLEAAVSSQQSPEPSLGLRVQETWGKATHSVGELTFGLFDLGIWLLAYTPYFLVIGAGVYGFKRFKKSQSVTRIEELKPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6S2</accession>
    <name>A0A2G4F6S2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57401">
        <property type="protein sequence ID" value="PHX57401"/>
        <property type="gene ID" value="CP500_000220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025528">
        <property type="entry name" value="BrnA_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14384">
        <property type="entry name" value="BrnA_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10572" checksum="B092CB84C2AA37BA" modified="2018-01-31" version="1">MNNEFTSSKSETDWERLDAMTDEDIDFSDCPEITPEMFAKAVVRRGLPNPKTKAQVTLRIDSDVLEWFKSQGRGYQTQINALLREYMKAHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Y3</accession>
    <name>A0A2G4F6Y3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 57 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57347">
        <property type="protein sequence ID" value="PHX57347"/>
        <property type="gene ID" value="CP500_000780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021923">
        <property type="entry name" value="DUF3536"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004300">
        <property type="entry name" value="Glyco_hydro_57_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12055">
        <property type="entry name" value="DUF3536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03065">
        <property type="entry name" value="Glyco_hydro_57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_57" evidence="2">
        <location>
            <begin position="119"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="922" mass="104880" checksum="0B89D9551A9254EB" modified="2018-01-31" version="1">MVSIFQTKSDQLTFSDKGEVAAGTQNIPATATGVCVTVHGHFYQPPRENPYLDAIERQGSAHPFHDWNERINYECYRPNAFARILNDRGEVAGIVNNYEYLSFNIGPTLMSWLQRYDAEVYQRIIEADRKSCQRLNGHGNAIAQVYNHIIMPLANERDKHTQIRWGVADFRSRFDRDPEGMWLAETAVDYATLEVLVAEGIRFIVLAPSQAERCRHLPSHDNSNPEWHEVGGGQIDPTRPYRCYLKPELRWAVSNQLSPLSSHNSSRGNGHNSEATTNTPYIDIFFYDGPISRDMGFNDVLSTSNHLAGRLGQAVRGDHRPAQLISVATDGETFGHHKHSTEKCLAYAFTEEFPRRGWTVTNFAHYLSQNPSAWEVELKPVTAWSCSHGVDRWQDDCGCGGGGGWHLKWRRPLRDTLNWLRDRLIPIYEEAGRKLFRDPWAARDEYIDVIGDRTQANVDNFLSKHQLHPLDAAEQVDALRLLEMQRHALLMFTSCGWFFEEISRPEGVQILRYAARAVELAGEVTGVQLEKDFVDRLDLAPSNVECFKTGAEVYRQLVTTAQVSLKQVAAHYAISSLFAKYPREQRVYCYQAQQLDFQIQRMGSMTLGVGQLQLTSEITRETELFVFAAFHLGGWDFHCCIQPFGSDRSYTMLKQRLFGVLQEASAAHAILEMVRLFGDQSFSLRNLFAEERHRIVRLLSQENLTRLDQLYTQVYRENYGVMMAFHRDELVVPVELQVAAEVALGHRCLTAAKALERETADAESLLAEIEAISTEANNLRCWLKVPEVRHILERLIYRFLKALLQEGSDLTLLSPIELEVDIRSIERLIAVGNRLGLGLCLDRSQELYFDSMHSQIVPLCLGWLQRQTGSTTKSAIDPVGLDILDSDSGWELPVIRQLLELGQTLAVDVECWLDQLGRSFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUF9</accession>
    <name>A0A2G4EUF9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GSH synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <shortName evidence="10">GSHase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">gshB</name>
        <name evidence="13" type="ORF">CP500_022980</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + glutathione + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the prokaryotic GSH synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000255">
        <property type="protein sequence ID" value="PHX53164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53164">
        <property type="protein sequence ID" value="PHX53164"/>
        <property type="gene ID" value="CP500_022980"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00162">
        <property type="entry name" value="GSH_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006284">
        <property type="entry name" value="Glut_synth_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004218">
        <property type="entry name" value="GSHS_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004215">
        <property type="entry name" value="GSHS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21621:SF4">
        <property type="entry name" value="PTHR21621:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02955">
        <property type="entry name" value="GSH-S_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02951">
        <property type="entry name" value="GSH-S_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01380">
        <property type="entry name" value="glut_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="133"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX53164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="319" mass="34962" checksum="CB6D7C1FA3AE5F90" modified="2018-01-31" version="1">MKFAFIIDPLARLIPGHDTSVALMEAAQELGHEVWATQANELSVIGGKTWGMLSRVTLTPVILVDGRWVAAEVWYEVESPTLQPLEAMDAVFMRTDPPVNVPYLYATYLLDYIDPAKTLVVNSPKGLRDANEKMYALQFEGAIPETIVSQNKQVIRQFVEKKGAAVLKPLGGKAGEGILFLENGDRNLNSLVEISTQQGTVPVMVQTYLPEAKDGDKRIILLNGKPIGAINRIPTGNEFRGNMAVGGRVAKTEITDRELQICTQLAPVLQRDGLYFVGIDIIGGYLTEVNVTSPTGIREIDLFNGVSLGKQVIEWVVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUI6</accession>
    <name>A0A2G4EUI6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000246">
        <property type="protein sequence ID" value="PHX53195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53195">
        <property type="protein sequence ID" value="PHX53195"/>
        <property type="gene ID" value="CP500_022795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008565">
        <property type="entry name" value="DUF847"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05838">
        <property type="entry name" value="Glyco_hydro_108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="220" mass="25284" checksum="20906C95A25C8728" modified="2018-01-31" version="1">MSDKQPKQRQLKINWKPNLLLGLLLLSLAIPLPFAQKTLAQQQTGNLRQKLFQTALYFTLYFEGGFSNHPADKGGRTYRGILQTEYNAYRYSRGLPPLDVTQMSEAELLEIYKYYWDSSLSGTMHPTLAIVMFDTAVNFGINNSITFLQQALGLPQTGIFDSSTKAALKSANNRNTALQMINERIIYRYKRVQEDPSQMAFFRGWLSRDYSLWGYVNKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUJ8</accession>
    <name>A0A2G4EUJ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000237">
        <property type="protein sequence ID" value="PHX53222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53222">
        <property type="protein sequence ID" value="PHX53222"/>
        <property type="gene ID" value="CP500_022635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysacc_synt_2" evidence="2">
        <location>
            <begin position="86"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="539" mass="60282" checksum="7854730E1F863229" modified="2018-01-31" version="1">MNIASNPSEVFSKAEIIDRIQQLVPPGSGEPKDPEILAALQTLTAQLIAAYKADGKLENDPFDDVRDRTVHLYTTAVISKLKGKTILVTGGEGCVGNFLIEKLLELGVNKIISADKARCQNLEETHPTFERKGAVTFYAADIRNFEALKHIFEVEKPDIVFHLAAQRSPGLAEIQIRETVTTSLLGTQNVIQLCEEYDIENCIFSSTGKTSRYFTTEVYAASKKFAEWQFARAAQAGNVTYGMVRFTHMLENSLFCEQMSNKVQQSKTVNVHAPHRYVTAQNLVEAVHLLLNGLVLSVPGKLRFLTVRNLGWPTETLEVALYKILESGKNLPIYFQGLLPGYEEPFFMGQFDWSKPTEIHLLINVLEDPFRMIEDCGDIVSAEVAPFSLRVFDRQVSHLENLISDPDFPEAQIKQVLVAAEKEVISSSFAWSSATDLLKILQWGINPKKLQGYGTDISSYSEIIELLLQGMYGRLNREVLHSAGVTAEEFNQLMESLSTVDSMRSEVQYLRSVSKSSKEFKEPSQLTQKSDIVLLLDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUN2</accession>
    <name>A0A2G4EUN2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chlorophyll synthase ChlG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">chlG</name>
        <name evidence="8" type="ORF">CP500_022545</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000232">
        <property type="protein sequence ID" value="PHX53241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53241">
        <property type="protein sequence ID" value="PHX53241"/>
        <property type="gene ID" value="CP500_022545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046408">
        <property type="term" value="F:chlorophyll synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13958">
        <property type="entry name" value="PT_UbiA_chlorophyll"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006372">
        <property type="entry name" value="Chl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011799">
        <property type="entry name" value="ChlG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02056">
        <property type="entry name" value="ChlG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01476">
        <property type="entry name" value="chlor_syn_BchG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="336" mass="36435" checksum="61B742B33CBA1DAD" modified="2018-01-31" version="1">MSDSPPSQIPPETSPDSTQADSRSAKTRQMLGMKGAASGETSIWKIRLQLMKPITWIPLMWGVVCGAASSGNYTWNLENLAIAAACMLMSGPLLTGYTQTLNDFYDRDIDAINEPYRPIPSGIISIPEVVTQILVLLVAGIGVAYALDLWAGHEFPIMTVLTLGGAFLAYIYSAPPLKLKQNGWLGNYALGASYIALPWWAGQALFGKLDPTIMVLTLFYSLAGLGIAIVNDFKSVEGDRQLGLKSLPVMFGITTAAWICVLMIDIFQAGIAGYLISIHQNLYAVILLLLIVPQITFQDMYFLRNPLENDVKYQASAQPFLVLGMLVAALALGHTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUQ2</accession>
    <name>A0A2G4EUQ2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cobalt transport protein CbiN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Energy-coupling factor transporter probable substrate-capture protein CbiN</fullName>
            <shortName evidence="10">ECF transporter S component CbiN</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cbiN</name>
        <name evidence="11" type="ORF">CP500_022405</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the CbiN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000226">
        <property type="protein sequence ID" value="PHX53269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53269">
        <property type="protein sequence ID" value="PHX53269"/>
        <property type="gene ID" value="CP500_022405"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00330">
        <property type="entry name" value="CbiN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003705">
        <property type="entry name" value="CbiN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38662">
        <property type="entry name" value="PTHR38662"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02553">
        <property type="entry name" value="CbiN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 10" id="KW-0171">Cobalt transport</keyword>
    <keyword evidence="7 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="11810" checksum="63CAAB4CF610FC1A" modified="2018-01-31" version="1">MSQKPTKNKQATSQQNWMLVIAVVALAVIPLVFVRGEYGGADGEAQKAIAEIQPDYKPWFNHLFEPASAEVASLLFATQAALGAGAIGYAIGLYKGRTESQQSDDKSPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV26</accession>
    <name>A0A2G4EV26_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53338">
        <property type="protein sequence ID" value="PHX53338"/>
        <property type="gene ID" value="CP500_022050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8056" checksum="D91814B5F4CE8880" modified="2018-01-31" version="1">MPIELIILIASLLVSWLVFNWAVKVLKASMGTAIALAVIVLTMQLMFGIGPNQLFQYIIHLPETLWRMTSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV38</accession>
    <name>A0A2G4EV38_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53348">
        <property type="protein sequence ID" value="PHX53348"/>
        <property type="gene ID" value="CP500_021925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9237" checksum="A97F15361C7E5840" modified="2018-01-31" version="1">MGGLINPLIFQQISMVKSHSLYFERSRLGFTVGRGRVYEIVNFRQLLSANPPLQKSLSSFFLLLTTANSQQSTFNSQLPTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV47</accession>
    <name>A0A2G4EV47_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53336">
        <property type="protein sequence ID" value="PHX53336"/>
        <property type="gene ID" value="CP500_022040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="263" mass="29881" checksum="8B94237A9B22F798" modified="2018-01-31" version="1">MLMNNCPTILALDFDGVICDGLIEYFQTAWRTYCQIWKPIQTVPDSDLASSFYRVRPAIETGWEMPLLIRALLTGITEEQILLDWPNIVPQLMTKNGLKAAEVSAMLDGLRDNWIAEDLTGWLSLHRFYPGVAESLQKLQESSVKVTIVTTKEGRFVRELLQLAGVKMPSQLIYGKEYNKPKHQILREFLAASGEDSTIWFVEDRLKTLLSVKQQPDLSNVKLFLADWGYNTLAERESVAQNPPVKLLSLSQFSADFADWLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVN0</accession>
    <name>A0A2G4EVN0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-glucose 4-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000174">
        <property type="protein sequence ID" value="PHX53602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53602">
        <property type="protein sequence ID" value="PHX53602"/>
        <property type="gene ID" value="CP500_020640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="316" mass="34987" checksum="BC87D1703F2D48DC" modified="2018-01-31" version="1">MSIFIVTGAAGFIGSNLVQTLLNRGETVIGVDEFNDYYDPNLKRKNIAEFEKYPGFKLVEGDILSLNWQSLLSDAKVIFHQAAQAGVRASWGDGFRSYTERNINSTQVLLEAAKKAPNLQKFVYASSSSIYGNAESFPTSENACPQPVSPYGITKLAGERLCGLYYQNFGIPTTSLRYFTVYGPRQRPDMAFHKFFKSILLDQPISIFGDGLQTRDFTFISDCVAANLAAAEVTEAAGEVFNIGGGSRVILKEVIDTIEQIVDRPIRISFTEAARGDARHTSADVTKAKKILGYQPQVSLEAGLRQEWEWIQSLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVT2</accession>
    <name>A0A2G4EVT2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine desulfuration protein SufE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SufE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000168">
        <property type="protein sequence ID" value="PHX53641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53641">
        <property type="protein sequence ID" value="PHX53641"/>
        <property type="gene ID" value="CP500_020390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003808">
        <property type="entry name" value="Fe-S_metab-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597">
        <property type="entry name" value="PTHR43597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02657">
        <property type="entry name" value="SufE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufE" evidence="2">
        <location>
            <begin position="16"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="16199" checksum="00562FB54A23E6DC" modified="2018-01-31" version="1">MSVNTALPAALAKIVQRFQRHADPKQRYEQLLWYAKRLPAFPEGDKLPENKVSGCVSQVYITANLTDGKVLFQGDSDAQLVKGLVGLLVEGLSGLTPAEIVSVTPDFIQDTGLNVSLTPSRANGFYNIFQMMRNKALACQLSEQAETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVV3</accession>
    <name>A0A2G4EVV3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000167">
        <property type="protein sequence ID" value="PHX53649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53649">
        <property type="protein sequence ID" value="PHX53649"/>
        <property type="gene ID" value="CP500_020345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="163"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="410" mass="46072" checksum="FD0CB293D02B2A17" modified="2018-01-31" version="1">MTTNTNTQEQFISVLTASIESQEFVRLTLGKYRGKEEFLNKIVAKIIKIKSGIRLSLTYCYKTKEIGKNHSIQEGIDLINTLIGKDFMSSRLFTIKQDVQLEYGNHQKLKLSFIKPTFPNSTTTIPQEHDRKKKRLIEAENNPYLTALGITNKEGNIVKTMEDKFRQINKFIEIVDGLLESSGLAASNHLSVVDMGSGKGYLTFAIYDFLNNILNKQASVTGIESRTDLVAFCNSVTESVNFENLHFEPGNIKSYSAEKTDVTIALHACDTATDDAIYQGIKSDSSLIILAPCCHKQVRKEIHPSTSVKDLLKFGILLERQSEIVTDGLRALLLELSGYEAKVFEFISSEHTSKNIMIVGIKSNRSIDKVQILAQIKEIKSLYGIKFHYLETLLFPNQLFSPDLADLIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVV7</accession>
    <name>A0A2G4EVV7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000164">
        <property type="protein sequence ID" value="PHX53673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53673">
        <property type="protein sequence ID" value="PHX53673"/>
        <property type="gene ID" value="CP500_020245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="353" mass="35368" checksum="E6624EA8160409DA" modified="2018-01-31" version="1">MNSTEHLSADEFLIRHGNGERDFRGYNLIKANLSEANLSRTNLSNANLKGANLIRSKLIAANLNGADLSGANLSRAKLIETNLGGSSLTGTIAIGADFSGANLTGAILSHADLSKAILIGASLVGACVLNGSKLTEANLSGATLSRAILSGVDLSRANLNRAIMSEIDLSGANLIGATLIRAYINRGNLGGVNLVEASLSEASMREASVCAANLSGADLSGADLQSANLNGSNLSGANLQGANLSKANLNGLILQNADLRAANLNKASLRGANLSGANLSGASLLEADLRGANLSGANLSGAGLLLSSLAGANLTGANLSEANLIGASLNVANLNEAALSGAILPNGATHSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVY0</accession>
    <name>A0A2G4EVY0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR01548 family HAD-type hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000163">
        <property type="protein sequence ID" value="PHX53684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53684">
        <property type="protein sequence ID" value="PHX53684"/>
        <property type="gene ID" value="CP500_020190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006438">
        <property type="entry name" value="HAD-SF_TIGR01548"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01548">
        <property type="entry name" value="HAD-SF-IA-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="267" mass="29491" checksum="1C1A173DAB5458B5" modified="2018-01-31" version="1">MTVDRAIVVFDIDGVVRDVSGSYRRALADAVEHFTAGAFRPNSVDIDSLKSEGVWNNDWEASQELVYRYFERIGRSRVDCAIDYNDLVAFFQSRYRGPDDQNWTGYICDEPLLLSPAYLKSLTEGGIVWGFFSGAMRAEATYVLSGKLGLNSPVLVAMEDAPGKPDPTGLFTTIEKLEKLNGLAENSPVIYAGDTVADIYTIVKARQLQPSRVWLGIGILPPHVLDDVVRCKAYTAALQNAGAVCVLRNVEELTPELIWELGIGHWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW32</accession>
    <name>A0A2G4EW32_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53762">
        <property type="protein sequence ID" value="PHX53762"/>
        <property type="gene ID" value="CP500_019825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7564" checksum="D12960C3330ED910" modified="2018-01-31" version="1">MGNWLFAPTFKGVIESYELSNYHCNSSVAQLPRTGKMPVPQRVNFLVEQAGKPVHKQLIENGVTYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW58</accession>
    <name>A0A2G4EW58_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_019575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000154">
        <property type="protein sequence ID" value="PHX53792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53792">
        <property type="protein sequence ID" value="PHX53792"/>
        <property type="gene ID" value="CP500_019575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="26406" checksum="84C53CBAF5278B69" modified="2018-01-31" version="1">MPTIEVQDLVFSYPQQKPVLQGISFTLQPGERVALLGLTGAGKSTLLENLIGLKMPQSGEIRVQGTKLEEATLSQIRKQIGFCFQDANDQLFMPTILEDVMFGPRNYGVPLGVARDRALALLDEFRLVEFANRSAHELSGGQRRLAALAAILALEPAILILDEPTSGLDPSWRRHLAKVLSQLPIEVILIASHDLNWIGKTTGRALILADGQIRVDEQTQELLKDRSTLEYYNLPPDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW70</accession>
    <name>A0A2G4EW70_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53718">
        <property type="protein sequence ID" value="PHX53718"/>
        <property type="gene ID" value="CP500_019985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="21053" checksum="4F7EDFAAF8A6AB6E" modified="2018-01-31" version="1">MSTTERVRWTTADLELLPDNGNRYEIIEGELVVTRAPRWEHQNIVDNVCRTLNNWSIETGLGKAATTAGLIFTDGDNVIPDVVWVSYERLAQILDESGHLAGAPELVVEVMSPGEENERRDRQSKLKLYSVQGVREYWIFDQRQQKVEVYLRENGVLKLAMTLFKEDNLTSPLLPGFSASVATLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWB8</accession>
    <name>A0A2G4EWB8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HEPN_MAE_28990 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000152">
        <property type="protein sequence ID" value="PHX53819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53819">
        <property type="protein sequence ID" value="PHX53819"/>
        <property type="gene ID" value="CP500_019435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040788">
        <property type="entry name" value="HEPN_MAE_28990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18737">
        <property type="entry name" value="HEPN_MAE_28990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN_MAE_28990" evidence="1">
        <location>
            <begin position="6"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="230" mass="26517" checksum="4415CD7FFAD32679" modified="2018-01-31" version="1">MQTVLLDFHTRVQEVNQYFEFLEMLIQETTKSPVSADNGEQKITAIDSELAKILKANAFLLLYNLVESTMRNAIEAIFAEISSRKISFNSLRTEIKKIVIYNFKNRSPDKVHSKIKDISIDIITAGFNSRELFSGNVTRKVITETARNYGFSFDTDYSKTKHGEHLEDIMDHRNDLAHGNKSFAEVGQKVSIEDLLKVKEEVIEYLQQILQNIQDYLDKQEYLDKSIQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWD1</accession>
    <name>A0A2G4EWD1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
            <ecNumber evidence="4 8">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ilvB</name>
        <name evidence="13" type="ORF">CP500_019710</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 8"/>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53778">
        <property type="protein sequence ID" value="PHX53778"/>
        <property type="gene ID" value="CP500_019710"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="13"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="207"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="404"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="zinc_ribbon_2" evidence="12">
        <location>
            <begin position="589"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX53778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="611" mass="65962" checksum="52E14C2BB3873397" modified="2018-01-31" version="1">MQLKTKVAIKRATGAFALIDSLRRHGVKHIFGYPGGAILPLYDELYRAEAEGGLKHILVRHEQGAAHAADGYARATGQVGVCFATSGPGATNLVTGIATAHMDSIPMVIITGQVPRPAIGTDAFQETDIYGITLPIVKHSYVVRDPRDMAKIVAEAFHIASTGRPGPVLVDVPKDVGLEEFDYLPVEAGAVRIPGYRPTVKGNPRQINQAIHLLKEASRPLLYVGGGAIAAAAHDEIKELAELFQIPVTTTLMGKGAFDENHPLSVKMLGMHGTAYANFAVTECDLLIAVGARFDDRVTGKLDEFAARAKVIHIDIDPAEVGKNRGPEVPIVGDVRQVLIDLLRRCRETGVSGNPGQTVAWLERIDGWKRDYPLVVPHYSEILSPQEVISELGIQAPDAYYTTDVGQHQMWSAQFLNNGPRRWISSAGLGTMGYGLPAAMGAKMALPQEQVICIAGDASIQMNIQELGTLAQYGINVKLVIVNNGWQGMVRQWQQAFYGERYSSSNMTVGMPDFVMLAQAYGVKGMLVSEPGELKGAIAEMLAHDGPVLMDAKVTRDENCYPMVVPGKSNAQMVGLPDRSKLELAELIYCPSCGAKNVSTNKFCPECGTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWE1</accession>
    <name>A0A2G4EWE1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YgiT-type zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000189">
        <property type="protein sequence ID" value="PHX53497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53497">
        <property type="protein sequence ID" value="PHX53497"/>
        <property type="gene ID" value="CP500_021200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022453">
        <property type="entry name" value="Znf_MqsA-type"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03831">
        <property type="entry name" value="YgiT_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8834" checksum="8A0604CEB984247A" modified="2018-01-31" version="1">MSNELWKETLIEQTVNYTLEMDGNFIIIENVPARLCLETGERFFSPETVERLQQIIWKRNKPSRTLEVPVYEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWG2</accession>
    <name>A0A2G4EWG2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000148">
        <property type="protein sequence ID" value="PHX53861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53861">
        <property type="protein sequence ID" value="PHX53861"/>
        <property type="gene ID" value="CP500_019265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="142" mass="16526" checksum="ED511357FD6EFC2D" modified="2018-01-31" version="1">MTYQNPTPTVDIIIELVDRPHRPIVLIERRHPPYGWAIPGGFMDCGESAETAAKREALEETSLKVELIEQFYVYSDPNRDPRQHTISIVFLASTTGIPQAADDAKNLEIFESWRIPAKLCFDHDRILRDYWRYRHYGLRPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWK5</accession>
    <name>A0A2G4EWK5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53925">
        <property type="protein sequence ID" value="PHX53925"/>
        <property type="gene ID" value="CP500_018885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="11506" checksum="88E81F669D51E2A2" modified="2018-01-31" version="1">MQKRKKQQKKRSLLETVVGIGILAVIVLFTMEFSPSRSPSTITSITKPGCTIKGNISINTGNKFYHLLGMEDYESTVINPASGERWFCTESEAKANGWRKAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWN9</accession>
    <name>A0A2G4EWN9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rplU</name>
        <name evidence="4" type="synonym">rpl21</name>
        <name evidence="6" type="ORF">CP500_020655</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53587">
        <property type="protein sequence ID" value="PHX53587"/>
        <property type="gene ID" value="CP500_020655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="14791" checksum="750E02245BA54ED9" modified="2018-01-31" version="1">MTYAIIETGGKQFRVEPGRFYDIELLHVEAESKVTIDKVFLIQHENDVHIGQPLVENATVEGTVLRHFRGRKVLVYKMKPKKKTRKKKGHRQETTRFMIDSISVNGVVLAARDLTQAVVETPQTGESDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX03</accession>
    <name>A0A2G4EX03_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Site-2 protease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_018155</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000128">
        <property type="protein sequence ID" value="PHX54064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54064">
        <property type="protein sequence ID" value="PHX54064"/>
        <property type="gene ID" value="CP500_018155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044838">
        <property type="entry name" value="EGY1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31412">
        <property type="entry name" value="PTHR31412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="8">
        <location>
            <begin position="376"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="492" mass="54333" checksum="E198551981123C86" modified="2018-01-31" version="1">MMFFLWLFVLGLISYFLLQSSISRITRTPVWLLWLVIMAPALIWSGWILVSGPSKSSPPDWLIIPFLVCPFLYWLLVQLGRKEITSETAEITAGDGTEPAKAKPKPALRPITPEEETSLRDCFPWSIYFLQNLEFRPQAVVCRGHLRTNPEVAYETIRQNVERHFGDRFLVIFQSSFSGQPFFAIVPNPHRQSAENSVKNEPLSRPLFALGLVVITLFTTTIVGAQLAGVTEKIVQSNPSMLIKGLPYAITLMVILGIHESGHYLAAKFHKISTTLPYFIPVPFFLGTFGAFIQIRSPIPNRKALFDVGIAGPLAGLVATLPFLIWGLYHSTVVPIAKNSGMLNFESFNPNFSLMMALLSKLTLGAALSSETAINLHPVAVAGYLGLIVTAFNLMPVGQLDGGHIVHAMFGQRASMAIGQVARLCMLLLSFLEPGLLLWAIILFLTPLNDEPALNDVSELNDWRDALGLVAIGLLLAILLPAPRILVQWLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX70</accession>
    <name>A0A2G4EX70_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54121">
        <property type="protein sequence ID" value="PHX54121"/>
        <property type="gene ID" value="CP500_017820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12943" checksum="2786B0B9A3DFBE1F" modified="2018-01-31" version="1">MAKLPDQTISTIFRLQQRLVALLDTATAAEYSLLQQFGETQETMPELEAIDNVKERLRIPYNRLHRILQQVAESQPAATADVLDFLYRTIDQGEAIADASEASIQEIKRSWNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXC9</accession>
    <name>A0A2G4EXC9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017930</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000125">
        <property type="protein sequence ID" value="PHX54100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54100">
        <property type="protein sequence ID" value="PHX54100"/>
        <property type="gene ID" value="CP500_017930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="130"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="130"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="232" mass="26210" checksum="97325F924AB7AE2C" modified="2018-01-31" version="1">MTPEKILVVDDDPAIRNLIHRFLSQQGYQVESGEDGQTGLELFEQLNPDLVVLDVNLPDTTGYKLCKEMQSRTGVFVLMLTGRTDEADKMKGFAEGADDYITKPFSLVEIGARVAAILRRVRQKKNPPEPQIRVFGQLAIDPVRREVVLAGQMVALTALEFDLLYCLASKPGRVWRRSELLQKVWDYEYVGADRVVDVHIGQIRRKIEPDGNQNSMIQTVRGVGYKFVETTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXM9</accession>
    <name>A0A2G4EXM9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54236">
        <property type="protein sequence ID" value="PHX54236"/>
        <property type="gene ID" value="CP500_017170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="91"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="220" mass="25210" checksum="EFEF7AE58ABF56E2" modified="2018-01-31" version="1">MLLPADRRTKLDDTDDNLFYAYPRFVTHVDEGFIQQLTDLYRERLKPQTRIFDMMSSWVSHLPDEMEFAHVEGHGMNQEELAKNSRLNHYFVQNLNTNPKLPLPDAQFDAVVNCVSVQYLQHPDRIFSEIHRILKPGGVAIISFSNRMFSQKAIAAWREGSEGDRVKLVKSYFDSVKGANIPGFSKPEIIFKESSLPSFMKMLGIGSGDPFYAVVAYRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXP3</accession>
    <name>A0A2G4EXP3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycos_transf_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54299">
        <property type="protein sequence ID" value="PHX54299"/>
        <property type="gene ID" value="CP500_016830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="79"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="576" mass="65354" checksum="268242AF15D997C9" modified="2018-01-31" version="1">MSVHVYPKFTYDDVPSRVYEATLNSVAMFDKLGKPDRIVANSHYVAQYLLQVYGRIVEDIVYPGVVCANQIVEISLHVQFLAVGQLWPHKRVKMIIEALAMLPDARLVIVGNGPEREKLERMALSLGIQDRVCFKHELSAEELRAEYNACRAVVFAAAREPFGIVPLEALAHGRPLIAVNEGGYTEVVDSHCAMLVPPRPQDLADKMNLLARDIDLARAMGEAGWKKAQQYSWNNSANQLIKIIESTFNTYAHDHKRCNGGTAIDRPLIGVQYYCWYGDGAGSLHWNDNLEFGAVDDMPEIGFYSSLDGDALKYHLQLMDRNGVDFLVANLHIDSNGVNDLELAGLLRLFHVAEILESPIRIAIQLCPYDLSHDSLDRAIATLNEMSKSPHYFRFESQPVIFMFWTGAWDGQRDEIENLKAATDGFLRIACSLRLPSDTESLYQTFGLFDSWSLFSPLEVASSENWQRVWAEAYRRSDCGNRGIRSVTVSPGYDDRHLSDLRRDNNLFRCIDRNCGKTLDAMTEFVLRQSDMPQMVLVSTFNEYHENSHIEPTKRHGLQYMEAIKDFGKALRSQWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY69</accession>
    <name>A0A2G4EY69_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000097">
        <property type="protein sequence ID" value="PHX54485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54485">
        <property type="protein sequence ID" value="PHX54485"/>
        <property type="gene ID" value="CP500_015840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SLBB" evidence="2">
        <location>
            <begin position="385"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="512" mass="54498" checksum="6339A7FAC1F50B4B" modified="2018-01-31" version="1">MAVFHQLGYLKVTNQITLYIVNASLPRQIIPILAGLSLLAITDIACPPPTIAQQPTLPNATPVRVRASNTNGTYTLGGGDNIRIDFFDLPQFSGSYQIPAGGVIQLPLIGSISIQGLTLEQANTAISNAYKPILKRPQVTLSLQATRPLNVWISGEVNRPGSYTIALNSGAGNAPSVQFPTLVQAVEKAQGVTQVADIRRVELRRRVGRVGQLQTTTFDLWQYLRTGNVPVDITLRDGDAIFVPTATAVNLAEARQIAISSFASPTNQARTVGVVGEVVRPGRYVVVGGDTSSGQGLPTVTRAIQLAGGLKPQADIRQVLVRRPTSGGTEKIFTVNLWQLLESGDVNQDTILQDGDSLVVLTATEINPAEISQIADASFSPAKIQVNVVGEIVRPGVVEVASNTTLNQALMAAGGFNSSRAKKSSVELIRLNFDGTVSRRMVEIDFAQGINEQNNPLVRSKDIIVVRRSTTAGVIDNINLILNPAAGILAVPSAGNAIISLLNNLGLIRLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYC2</accession>
    <name>A0A2G4EYC2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54450">
        <property type="protein sequence ID" value="PHX54450"/>
        <property type="gene ID" value="CP500_016090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="167" mass="19167" checksum="4D32B50B28AD4C36" modified="2018-01-31" version="1">MARQLIMAIAESAESLEQQLKTSRTASQKERLQMLWWLKTGQITQHKTLAERLGRDGSTVTRWLQKYRQGGLSELLTVKSAPGKLPHLSSEAIAGLQERLQQPPGFKSYGEIVKWLNQTYQLNLTYPTVYHWVHYRLKAKLKVPRPKSAKQEPNAAQRFKKTSPQPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYE2</accession>
    <name>A0A2G4EYE2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fabG</name>
        <name evidence="4" type="ORF">CP500_015490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54555">
        <property type="protein sequence ID" value="PHX54555"/>
        <property type="gene ID" value="CP500_015490"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="20"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="163"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="254" mass="26581" checksum="B6536D9FDCDF8742" modified="2018-01-31" version="1">MELLPETFQRLRGQVALVTGASRGIGRAVALALATEGAKVAVNYASSSAAADEVVAEVVAAGGEAVALVADVSKNDQVDLLTSNVMEKWGRIDILVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCTKAASKIMLKQRSGRIINIASVAGQMGNPGQANYSAAKAGVIGFTKTVAKELSSRGITVNAVAPGFITTDMTKDVKSDEILKYIPLGRYGEVEEVAGMVKFLAADAAAAYITGQVFNVDGGMVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYF5</accession>
    <name>A0A2G4EYF5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000097">
        <property type="protein sequence ID" value="PHX54490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54490">
        <property type="protein sequence ID" value="PHX54490"/>
        <property type="gene ID" value="CP500_015865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="305" mass="34132" checksum="225ED5DEDA23EB86" modified="2018-01-31" version="1">MEQTSIAVLMTCHNRKSKTLATLESLFQQVSISEITHKVYLVDDGSTDGTGEAVQQTYPDVKIFSGDGNLFWNGGMRVAFSEAIKDDPDYYLWLNDDTILYPEALSSLLTTSRQLCEQGEKKAIVAGSTCDPDSGDFTYGGIVKITPLLPFKFRFLEPTKAPQSCDSMNGNCVLIPRSVVQLVGNLDPAFIHYLSDWEYGLRARQKGCTVWIAPGYQGTCSPNPQSTKVAAANMSEGLQKMNQPKGLTFQDATLQPWEEWKVFAQRHGGLFWPIYWLLPYRRLVWFFILSKLGLTKNKIQGESDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYS1</accession>
    <name>A0A2G4EYS1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_014865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54663">
        <property type="protein sequence ID" value="PHX54663"/>
        <property type="gene ID" value="CP500_014865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="533"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="606"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="704"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="848"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="499"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1092" mass="120701" checksum="770F4ADB07EE0D82" modified="2018-01-31" version="1">MNLQPASITDLASTPMAQTQSNNLNSNCPQPTTAVSSDKFAAVVMPCIYNLSLTRKQLIGLLVLPIILPMGIAGVALWMILTAGMSQLQNQAKSELVVSEINYNLKLDRATFSLKNSSDRLAIAQTAIAYNSGKKSPYLQKSVKQILENQVKIGGIHSAVLVGKDGKIIVSVNLNQEGQSFNPRNLAYPVLAKKEPITASKILAKSENQKQLPTLQPRFSESVIVNYAEIPVNNPKNKTVIGGLFLGENLSKMPMVASTETVNSLGGFYAIYAPLNEGKYVLVSAQNVTKNQLLPDLQWMDRSVLGSAALAADRQPVGRQIKIGNQTYTVAAKSLKNLAGKPAVILVRGIPQTGLGDNWLLLALFGAVLVVPIGLAIAIARKANFRLGIWDLGLKEKQTPNFMPSEDEDGHNLTSQSQTLKQFDELNFDRIPNLFAKTINSNTPLAINFNYKKLFADSRSLANFPTPLNFKPLELPLPASSDSHQQLPAEETNCCFINVNQTRQSLQDLNRLNLELQQEIVDREHTEKALQNSQGLLQAILDNSTALIHIKDAEGKYLLVNRYFETLFHITKQQIADKTDFDIFPKEKAEILRANDLKVILEDSPLTIEEVVPLDDGQHTYISLKFPLYNSEGIAYAVGTISTDVSERKLAELALEKAKEKLEIEVKERTMFLRQSNEQLQLELSARVRDAISVRQMTTQVARHARTVDGILDASLDLIFLVNQSGKYTYISRTAAQATGMNPREMIGKSWQELGWSPQIMEQVHQKCKAIFATKMPAKGEVIIPTATWGMRDYEYILSPVCATDGSVEAVVATLRDITERKDAEEAWQLAKEAAELANRAKSAFLANMSHELRTPLNAIIGYSDMLAEDAQELGDEQTVSDLNKIRNAGKHLLRLIDDILDISKIEADKMELCLESFDVGGLIEEVAITVKPLMEKNQNTLQVNIPKGIGAMHADLMKVQQVLLNLLSNAAKFSTLSAIALNVERVTSEELKNKYQPTVAQMLILDSDFLIFRVSDTGIGMTKEQQQRLFQPFTQADNSTTRKYGGTGLGLTISQRFCQMMGGDIEIESEIDCGSTFTVCLPAALFKRHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYV4</accession>
    <name>A0A2G4EYV4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54668">
        <property type="protein sequence ID" value="PHX54668"/>
        <property type="gene ID" value="CP500_014890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="462"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="592"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="630"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="767" mass="86179" checksum="D48814D6E6DFA01A" modified="2018-01-31" version="1">MILVKHLWELILFLIILVGPIPLCLDLSFDRKPENSNYSFAHFLLVFLTAWSIVQVSIGLILGSCDRLNIYAVILAEFAIFVVGSSLIYYKKSRDFYVINWQKLQLKESLSRGEWRIIFSVTLVGIILLENLATQPITNYDSLWFHLPVIARWYQTGSLTLLDATGNWIFDHEQARVYPYNWHILSALCLMPFKEDFLTAFPMLMAWVLEGLSVYLLGVKFGATRIHSMGASSLVLTVPMMLNQVNTIHPDLPLSAIFTVGLYLGLSYYKSRDLSELSLFLASTGMLAGIKITGLVYAASLLGGLAILEIKRFAFNQKSTQAKFRILHFIKPVLLCGLACFLLLGGFWYTRNLLHINHPVGDTKEILFPLQPVTIPSPVQPLPSPIKPPILSIQKPPVAPLFKIWQSTLAAQFNPSNIDHWKTLGLQIIIRLQVPFMAFVFQVLAAPLALTKGKAKIINENTMILTVLLACTGILYLITPYSSGTAGDSIGQISPLLSSNLRYGFPFLSVLGIAAAATATLLKTRNPVVVKLVFVSSIFGIISNTIFDTISNASFTGDSIVWGSLLIDNFKYNPLKAIQTIGQILAPYWPDILIPSIFYIVPISLLGWILLKINPGLGWLNNMFYTRRKLSYIVIIFVCIGLIVIGNWREQRDVADTKLYRGIYEYIDKNTVPDERIGFFLSSRSYLFYGKNLNRQVLYVPFRADRISAWIDNLRHNGVRIVGFGPLTQTDADTRKALSWLTSAEGPLEPVFGKDFKTKSVLYRLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ82</accession>
    <name>A0A2G4EZ82_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54497">
        <property type="protein sequence ID" value="PHX54497"/>
        <property type="gene ID" value="CP500_015785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17607" checksum="EA02C92B80A4961D" modified="2018-01-31" version="1">MKKLLDEILSVETSNRINSQPTKFFDNAYQAALAIEGTTYVQGFLVVSGIPDKVIEYSWIELGDRIIDPTFPHIGLNAENLYYFPAQSLSLKQITAIIEESKEDYPLDDPLPVYGDLPYEYYGDLMLGGKDYQTAYLLALDKCRELNPPQIEETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZD7</accession>
    <name>A0A2G4EZD7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3084 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54872">
        <property type="protein sequence ID" value="PHX54872"/>
        <property type="gene ID" value="CP500_013625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021435">
        <property type="entry name" value="DUF3084"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11283">
        <property type="entry name" value="DUF3084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="78"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="218"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="298"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="563" mass="62538" checksum="E3C69677386B38E8" modified="2018-01-31" version="1">MTAGYILVFVILILGGVIATVSDRLGTKVGKARLSLFKLRPRDTAVVVTVMAGSILSATTLGILFATSKPLRTGVFRIDEIQKRLNNARRELNQATQEKNLVETELAQARAAQSKVKANLEEINRSLQAANAEQAQTQAKLNSLRTQLNSVEAAKSKTEKQLSEVEVAKSQTESQLMSVEAAKSQTESQLKMVETARATTKSQLDRTESQLNTVSTQKTNLGSEIAQLQGERQQLIEQRERVKTQIAQRDQEIAKREGEIAKRDKEIAKRNELIAQRDQEIAQRVQNLADRDRTIVDRDKVISEREELLETLAEQQTQLEQQQALLQQQVQVLERDFQAIREGTVAIRRGQILAAGVVNIVDPALASRAIDRLLQEANKTTVGLMQPQNNSVKEQVVQITNTEIEQLINQIKDGQDYVVRIVAGANYLREEKRIKVFAEAEINRVVFRAGDLIAGISVDPVTSTDEQVRQQLQQLIEACQFRARLIGVVGGRVQVADNRIETLAGFVDRLQQYDKPLDVQAIATDVTYIAGPLKIDLVALQNGVVVFRTGQQPPGGPDVKVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZJ9</accession>
    <name>A0A2G4EZJ9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA interferase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Toxic component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PemK/MazF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54939">
        <property type="protein sequence ID" value="PHX54939"/>
        <property type="gene ID" value="CP500_013360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR033490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="12203" checksum="ADA4E14530E85643" modified="2018-01-31" version="1">MAMVVERFDVFLVNLDPTVGSEIHKTRPCLVISPDEMNKAIATVIIAPMTTKGKLYPSRIVCHFQGKDGQIILDQIRTVDKNRLVKYLGQISADEQKAVLDSLVQMFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZL2</accession>
    <name>A0A2G4EZL2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L,D-transpeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_013440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54952">
        <property type="protein sequence ID" value="PHX54952"/>
        <property type="gene ID" value="CP500_013440"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013915330" evidence="3">
        <location>
            <begin position="37"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="4">
        <location>
            <begin position="56"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="19147" checksum="68DE333E57DDA18C" modified="2018-01-31" version="1">MKNNINSTYCRHFGTFCAGFALTIAAFCSSSNGVIAGEKHNTIAYKVMELQQSSQRWIEIDLSRQKLIAWEGNKPVYAVVISSGKSSTPTRTGTFAIQTKYRVTRMAGPDYDVPDVPYTMYYDGGMAIHGAYWHNLFGNPVSHGCTNVAVNHAKWLFNWASVGTAVVVHKSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZP4</accession>
    <name>A0A2G4EZP4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-binding transcriptional accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54980">
        <property type="protein sequence ID" value="PHX54980"/>
        <property type="gene ID" value="CP500_013235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="646"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="745" mass="83096" checksum="A6D2D53625B47B87" modified="2018-01-31" version="1">MLNIPQLIAQELSINLSQVNNALELFAEGATIPFIARYRKERTDSLNEIHLRDISDRFTYLTEIEDRKKSILGIIATQGKLTPELEAKIEFCLLKTELEDLYLPYKQKRRTRATIAREKGLEGLAEFIKSLNTPQAQSVDIDGEVAKYISEEKGVKTSEEALKGAADILAEGVSEKAELRAYLRDFLMKTGIFVSKIKEDFPEGSTKFEMYRNYQIAARNVQSHNMLALFRGETDGVLDLDLVFDEAAVATYLESQEIRTKIPFVKEFYRSLLKDAFNRLMKTSLMTEVRSHNKAEADIESIATFETNLRELLLSAPAGMKPTLAIDPGFRTGCKVSALDETGQFLEYQAIFPHQAAAQRQQAGKIVKHLIEKYQIELIAIGNGTASRETDEFVAEVLAGLDRKPVKVMVNESGASIYSASEVAIAEFPDLDITVRGAVSIGRRLQDPLAELVKIDPKSIGVGQYQHDVDQKLLKKKLDETVESCVNYVGVDLNTASKELLTFVSGMTPTVAKNIVNYRNENGAFKNRRQLLKVPKLGPKAFEQAAGFLRIRNGENLLDNTAVHPESYAVVQAIAKDLNLPLTDVTQIAAKVKGLSIKKYVTEKVGEPTLRDIISELEKPGRDPRAEFKYATFQAGITKVSDLIVGMELEGIITNVANFGAFVDVGVHQDGLVHISQLADRFVEDPKQIVKVGQVVKVRVLEVNEKLKRISLTMRSQEQLKSDVKISLPQKTSTVNDLQAKFNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZU7</accession>
    <name>A0A2G4EZU7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase Obg</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">obg</name>
        <name evidence="8" type="ORF">CP500_013020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55031">
        <property type="protein sequence ID" value="PHX55031"/>
        <property type="gene ID" value="CP500_013020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="7">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="160"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="191"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="213"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="280"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="311"/>
            <end position="313"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="346" mass="36949" checksum="4054B996451894CB" modified="2018-01-31" version="1">MQFIDRADIQVAAGKGGDGMVAFRREKYIPAGGPSGGTGGRGGSVYMVAVESLQTLLDFQYNRIFKGDNGKRGAIKNMTGAGGDDRTIEVPCGTVVYDAETQAILADLVTPGQTFCVAKGGKGGLGNKCFLTNSNRAPDYAMPGGEGEHKFIRLELKLLAEVGIIGLPNAGKSTLISALSAARPKIADYPFTTLVPNLGVVRKPSGDGTVFADIPGLIEGAHEGAGLGYEFLRHIERTRLLLHLIDVTDEDPIANYMTIRDELKAYGRGLANRPQIFAFNKVDAIDLDSEEIGNLISRLQEVSGAPVLSISAVSRVGLDELMQQVWQKLDELNEKEATELLTVGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZW2</accession>
    <name>A0A2G4EZW2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55052">
        <property type="protein sequence ID" value="PHX55052"/>
        <property type="gene ID" value="CP500_012865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="21167" checksum="A4E30D64E035C5E1" modified="2018-01-31" version="1">MTATKAKIWTVEEYHRMIEAGILNEDDNIELLDGRIVEMSPQTPIHAGTTQRSDRYLQHLLRDLAEIRVQLPITLATSEPEPDIAVVCIDPGGYGDHHPNSREILLLIEVSYSTLQIDLREKNLIYARANIAEYWILDVVSRQAYIYRNPTPGGYQSEIVVTDNAVMKMLAFPEIEISFSELFLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZX5</accession>
    <name>A0A2G4EZX5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55069">
        <property type="protein sequence ID" value="PHX55069"/>
        <property type="gene ID" value="CP500_012665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="285" mass="31989" checksum="171271B5F573D532" modified="2018-01-31" version="1">MVNTVDDIARQAREGSVAAIIQILNDQLAEIGVRTRAVFTDGVLQLLCEAATVDLLEQSSLVDRLTQILEQLSPQNIRRVKINSRLVREHQLLWLEEISRDPENQLLWSQEIKLRRVYFWQRFAIDQKERQGHKPALPKMTTHPRLSMQEPRQFQRGLIGGIGLSVLLLTAVFAIYKGLNAPSPNSTTASTQAVATPIPESSPQQIVQVNSDSFAQAVRLAEQAVTEGKTAQSREDWLVVAAKWQQASDLMAAVPSKHPRYTTATNRAALYHQNSEKAQQEAQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZZ9</accession>
    <name>A0A2G4EZZ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55085">
        <property type="protein sequence ID" value="PHX55085"/>
        <property type="gene ID" value="CP500_012745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013754097" evidence="2">
        <location>
            <begin position="30"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="18508" checksum="4B502247EEEF7EFE" modified="2018-01-31" version="1">MGQNLKNLSSVLIIAIASATLASVKPAQAEPIRLQPLADSFNRQFFQSSGDFYHNVSLQGYFGDYLGIGSPSGVVAFPEKEIERDASRVNGFYRQTMQRQVSSDPILRVPDAANPFDSSVMALPPACQFAPQPSGCFPTATGATEPFVDQQQPQTAPGPVRGLYRVSPTGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F072</accession>
    <name>A0A2G4F072_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1822 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55155">
        <property type="protein sequence ID" value="PHX55155"/>
        <property type="gene ID" value="CP500_012290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014951">
        <property type="entry name" value="DUF1822"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08852">
        <property type="entry name" value="DUF1822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="285" mass="31537" checksum="642384A987EA00E4" modified="2018-01-31" version="1">MVNSMDTYLLEIPLEQTARNLALQFASEQANPQKGKRVYFNTLAVWAVNYFLEWMELETDIDGGDSWHPGMRAVLDVADLVLPGIGKIECCPLLLGETAISLPEVRENRIAYIAVEFAEPFDKVKLLGFIPAVEIVEETEEISLTNLQPVEELLDYLDRIELGIPVTQVLLEEELSDLEEALSDLKEDDPVKAQVREKLQNKSIAEIVAILNGVYGSSEKSDWGYEGGKALAGIGSSSGGLGNRETSLSGYKSSDIDTKVEAKLNRIAKKWMKKLAEIWGDGDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0D9</accession>
    <name>A0A2G4F0D9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55216">
        <property type="protein sequence ID" value="PHX55216"/>
        <property type="gene ID" value="CP500_012010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="218"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="277" mass="31761" checksum="CB27C7163751E999" modified="2018-01-31" version="1">MSQSIAPVLEEKQTDTSPTLTFEEYRVYQSNDDVQYELYKGKLIPMPTATVLHIKICEYLVYQLQRYLAAHNLNLVVKTGLGVRTDENKSRIPDVVVCTQSLVEQAAARPGAGILDFDEKPLLVIEVVSENRRADYAIKRGEYELANVPEYVIVDPKSGKQKIRLLAFIDGEESYTQTDFLPGEEMISVVFPDWVLSVDEILNPPFVEELVKAERARLQESQQQVVIERQRTQQLEQEAIIQRQRTQEERQRAQDERQRADKLAAKLRELGVDPDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0E7</accession>
    <name>A0A2G4F0E7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54927">
        <property type="protein sequence ID" value="PHX54927"/>
        <property type="gene ID" value="CP500_013490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="198" mass="22645" checksum="F32271AA086E2A95" modified="2018-01-31" version="1">MIATKENFPQMTPEEYFAWEEKQLEKHELIDGQVYAMSGGSVNHSRIAIRFATMVDTHLDASSCITGNSDLRVNIVGTNNYTYPDVSATCDDRDKSTTQYITYPCLIVEVLSPSTEIYDRSGKFRLYRKNPNLQDYLLVSSTAIEMDLYHKNEAGDWLIINYQEGDTIELKSINLSFPIEQVYRNLDLTPEPEPTKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0L2</accession>
    <name>A0A2G4F0L2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_011670</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55295">
        <property type="protein sequence ID" value="PHX55295"/>
        <property type="gene ID" value="CP500_011670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="26"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="280" mass="30879" checksum="302AAD6E157F9CCC" modified="2018-01-31" version="1">MLRSVKGFAQKARTVNGGRRTKLNLLATLVRRDLEAQYKGSILGNLWPLLNQLSQLLIYTYVFSIVLKVKLNLTGFPENSNITFGVWLFAGLLPWSAFTSGLIKSGVSVVGQPNLVKKVVFPLGLLPLVPIFTAFIESSLGLAALIVIVAVSSQKLNATLCLLPLVWIPQLLITAGLGYLTAGLTVFLRDIPQTLGVILNFWFYLTPIVYPASVIPEQWRGVIFWLNPMAAISEVYRDLILLGEVKHWGELGVATLISAAIFWGGLMVYRRLRPAFADVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0M7</accession>
    <name>A0A2G4F0M7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M61</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55306">
        <property type="protein sequence ID" value="PHX55306"/>
        <property type="gene ID" value="CP500_011415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024191">
        <property type="entry name" value="Peptidase_M61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007963">
        <property type="entry name" value="Peptidase_M61_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040756">
        <property type="entry name" value="Peptidase_M61_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05299">
        <property type="entry name" value="Peptidase_M61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17899">
        <property type="entry name" value="Peptidase_M61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016493">
        <property type="entry name" value="Glycyl_aminpptds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="501"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="624" mass="70619" checksum="57404DFA6878AAE8" modified="2018-01-31" version="1">MIDVTSLDTSSVATNIPTQLIAPKIEYSVAMPNPESHLFEVTLRVQGWSESVMDLKMPVWTPGSYLVREYAKHLQDFRSTTTGDRALSWSKKSKNHWQIETNSVSDVTVNYRIFANELTVRTNHLDSTHGYFNPAALCFFLPGFEQNCYTIKVVPPRPEWRIVTTLPAVYGEENTFAAADFDTLVDSPFEIGCHDVYDFEVMGKTHQLVIWGKGNLEPESVIRDIKKVIEVEAQMFGGLPYERYVFLLHLSGSGFGGLEHKDSCTLNYPRFGFRNRDKYDRFMQLVAHEFFHLWNVKRIRPKALEVFDYEQENYTPSLWFSEGTTSYYDLVIPFRSGLCGVKGFLHGLAKEITRLQTTPGRNVQSASESSWDTWIKLYRRDSNSDNSQISYYLKGEVVSFLLDLLIRAKHGNERSLDDVMRLMWQQFGQANFAQNNGSNKSGSDTITGINSLPSEIGFTPEQLQAVIESVAGVDLSDFLARYIDGKDELPYDKYLEPFGLQIAIDQTNEIPSLGWTLGVENGREIVKFVEVGAPAQLAGIDAGDELLAIDGFRVNSEQAGERLKDYRSGDAIEVTVFHQDELRTCRVTLAPPRPGHYQIVPVEQPSSIQKQNFTGWLGVPLSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0N9</accession>
    <name>A0A2G4F0N9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3'-phosphoadenosine 5'-phosphosulfate 3'-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55322">
        <property type="protein sequence ID" value="PHX55322"/>
        <property type="gene ID" value="CP500_011405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="31335" checksum="B8299FF211AA4D5C" modified="2018-01-31" version="1">MMYISPDQDQKIRSTMRKCGQLAQKLAAEPFEVSEKGPDDYVTSIDRLLDQQLLTAFSALFPEDGIITEENVASRAAYLGNYRRLWCIDPIDGTAEFIQGKLHYAVMVGLLQDGEPIAGWIYAPAFDQMYFGGKDWGLFQTLGDSKPSAIAIHKSTAPTADSCKIILGDKDQKNYGLAIAQMIPGVEFYSLGSFGLKVLEVISGRAGLYLYFNGRVKVWDTAGPLALAKAAGLVCCDLQGQPLRWTPDALNSESLAHSQTIAIGQPEYIECLLAKVRIAVEGLQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0P4</accession>
    <name>A0A2G4F0P4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55027">
        <property type="protein sequence ID" value="PHX55027"/>
        <property type="gene ID" value="CP500_013000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="12931" checksum="ECC1AC9E775C241D" modified="2018-01-31" version="1">MGIGNWESGIGNRELGIGNRESGIGNRESGIGNRESGIGNRESRIGNREWLLVSDFFNSQLPITNYQCPITNYQLPITNYQLPITNYQCPITNAQCPMPNFQFPMPHAPCPMPTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0W6</accession>
    <name>A0A2G4F0W6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arabinose efflux permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_012545</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55097">
        <property type="protein sequence ID" value="PHX55097"/>
        <property type="gene ID" value="CP500_012545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="334"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="520" mass="55794" checksum="B438DA87016013BC" modified="2018-01-31" version="1">MMRLSDSDLTISVLAVTHHKMEERENLSDFHSHPVDDQWSKVQDPEMAKYPTTPEPTWGNGNGKTPAETPAQPSIPEPAITDEAVVENPETERGFLPILKNRNFLALWSGQVFSQLADKVYLVLTIALVASHFQAADQTISRWVSAIMIAFTIPAVLFGAAAGVYVDRWPKKAVLVATNLLRGGLVLSLPVLLWLSDGLEIGQLPLGFCLLLLVTFLVSTLTQFFAPAEQSAIPLMVERRHLLLANSLYTTTMMGSVIIGFAVGEPLLALADTLFTNLGGGLGIGKELVVGGSYALAGVLLLSMNTGEKNEVEHEPPHPLADLKDGLRYINDQPKVRNALIQLIILFSIFAALAVLAVRLAEILPGMRASQFGFLLAAVGVGMAAGATTVGYLGNKFSHSQFSLIGSIGMAVALIGLSVFTHNLWISVLFITLLGVFAAIVGVPMQTTIQAETPEEMRGKVFGLQNNATNIALSLPLALAGVAETFLGLPRVFLALAGLAIAGELLTWYISRNSTVDRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F127</accession>
    <name>A0A2G4F127_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55462">
        <property type="protein sequence ID" value="PHX55462"/>
        <property type="gene ID" value="CP500_010725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11824" checksum="F8842AB43AF0F9B3" modified="2018-01-31" version="1">MPKALEEIEGTFTKLVQQWRNETIGISSTTDLVIHPAYQQIIRMGSVVIPLLLREVERKSGRWFHGLCEITGEDPVPLEKRGKTKEMTQLWLDWGKAKGYKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F143</accession>
    <name>A0A2G4F143_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55481">
        <property type="protein sequence ID" value="PHX55481"/>
        <property type="gene ID" value="CP500_010690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="614" mass="69806" checksum="AB56D270C3ED12A9" modified="2018-01-31" version="1">MQKHHKPDWYFNLSIYTFVIIGSLIAVGYKFPIGGNFPELPQIQHLLNPELYKNDYHVQEMVKFNPRYYYYHIIYLLASLGLSIPLVHFIYQFLAFASVVLACHAIINIYTNAKLPAAAMTFLCLASSFTDVGNTLIFSTKSVPSTFAMGFAIWGIYFSLRQKWLAGYFWFGLACLLQFLVGLLPGLMMMPVLIMESVRQRRFKNVILAIAILATLASIVYLPMLLTGTTGTHTMNNADFVYIHANIRNPHHILPSNWNVGNNWLNFIFLILGGLLCINNTNELRKEDKINFAIIIATSIFALLLNYLFVEVYPVALIAKLQLARTVPFAQIIIFIAISLLVNRLYKAKQLALSLLLLIIFTLPNRGILFLALFVFLSICQTPKYTIPKRYNILPWIFTAGTLIFSLIYPLTNSGEIIERLISMPVLFSIIAFPFILENLSISTAIKQVLTNILAFLTTSILILGIAGILPKPMLDIFQTRVNINAVPTDDLNQLALRFSQSSNQDALILIPPSVTSFQYFSQRAIVVNFKNFPLTEKGIKEWQNRMETVLGVPLNPQMIWGGNDLFSRRNSADLVQVARKYHADYILTRTDWHPNIQGEIADKQGKWILYKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F151</accession>
    <name>A0A2G4F151_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55490">
        <property type="protein sequence ID" value="PHX55490"/>
        <property type="gene ID" value="CP500_010305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="21"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="17911" checksum="689BFF4D073951C2" modified="2018-01-31" version="1">MVTTSTVDRTNLAQWHDVLAPHSIGYRLKLLGQLGTRRLQEALEPFGLTPFHWLVLCCLWQEDGLATSSIGDKLQQVGGTLTGVIDRMEERDLVRRSRDTRDRRIWRIWLTDAGRELQDVLPPLVRDIREKSMTGISKADRERFSELIDMAIVNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1B6</accession>
    <name>A0A2G4F1B6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55549">
        <property type="protein sequence ID" value="PHX55549"/>
        <property type="gene ID" value="CP500_010205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="83" mass="9438" checksum="7AECF0D8478681AD" modified="2018-01-31" version="1">MISQTLVEIERSISSLSIEEQLWLLERIACRVREKTYIANKLANAKYLEAEIAEMANDPDIQVEIAAINREFIVAEMDGLEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1B9</accession>
    <name>A0A2G4F1B9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Secretion protein HlyD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_010220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55552">
        <property type="protein sequence ID" value="PHX55552"/>
        <property type="gene ID" value="CP500_010220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="64"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="371" mass="39776" checksum="0F302836C38F2E9D" modified="2018-01-31" version="1">MPPIPEPTPAETLQNDQFLPPVSRWTTLGGILMVATFGGAIALASVTKYSATVKADAIVRPAGEVRVVQAATEGTVESIAVSENQIVKAGDAIAVVDASSLGNQKKQLQETVSASQTAAEQINQQLRDLENQILASAQFQTIPGESSAQKELVESAVVKLATSLPDVAERLGRSRRVLLVKRSSIQQQLIQSKKELTQIDLKLQNSVIRAPADGTILKLELKYPGQTVQAGSAIAQIVPSDVPLVVKAKVTSQDIARIQIGQPVQMRISALPFPDYGTLKGTVSEIAPDAIATQNPNNNLGTAYYEVAIKPDKTYLTRLESTSDQAFGTPQANIPRQYSIQSGMEGRADIITGQETVLTFVLRKARLLTDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1C5</accession>
    <name>A0A2G4F1C5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55538">
        <property type="protein sequence ID" value="PHX55538"/>
        <property type="gene ID" value="CP500_010295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
        <property type="entry name" value="GT9_LPS_heptosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="320" mass="35214" checksum="74057766F0F9F09C" modified="2018-01-31" version="1">MRILALVPGGIGDQILFFPTLDNLKQSYPNAQIDVIVEPRAKGAYRVCKSVKEVLTYNFKDRNAMADWGNLLGVIRDREYEAVISLGQRWSVGLLLWLTGIPKRVGYVGNNNTLFLTNPVPLKTEQYAAEMYHDLLQGFNINNACPRVAINVPKQDIQWAEAEQQRLGIKESGYILIHGGSSQLAVSKGIDKIYPIGNWQKIIEDCQQRQPNLPVVIVKGPEDASFVTELIKLCPKVKVTSPDDVGKLAATIAAANLMMCTDSAPMHLAVAVQTYTIALFGPTDPAKLLPKSDRFLGIKSPTGKMADISPEDVLKKVWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1L4</accession>
    <name>A0A2G4F1L4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Allophycocyanin subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">apcB</name>
        <name evidence="13" type="ORF">CP500_009635</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cellular thylakoid membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55661">
        <property type="protein sequence ID" value="PHX55661"/>
        <property type="gene ID" value="CP500_009635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12126">
        <property type="entry name" value="APC_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006245">
        <property type="entry name" value="ApcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34011:SF3">
        <property type="entry name" value="PTHR34011:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000081">
        <property type="entry name" value="Phycocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01337">
        <property type="entry name" value="apcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="11 12" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="8 12" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 12" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="2 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="169" mass="18559" checksum="36EA7F282C6074AE" modified="2018-01-31" version="1">MRDAVTSLIENYDVAGRYLDRDGIDRLKSYFATGTARVQAAAAINSNAATIVKQAGIQLFADQPELIRPGGNAYTTRRYAACLRDMDYYLRYATYAIVAGSTDVLDERVLQGLRETYNSLGVPIGPTVLGISIMKEMVKAQVEAAGLSVGAFLEQPFDYMIRELSETDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1L6</accession>
    <name>A0A2G4F1L6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamine synthetase</fullName>
            <ecNumber evidence="4">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">glnA</name>
        <name evidence="6" type="ORF">CP500_009630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55660">
        <property type="protein sequence ID" value="PHX55660"/>
        <property type="gene ID" value="CP500_009630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004809">
        <property type="entry name" value="Gln_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00653">
        <property type="entry name" value="GlnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="5">
        <location>
            <begin position="104"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-AMP-tyrosine" evidence="2">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR604809-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="473" mass="52970" checksum="D4D7BC5A536EDA0A" modified="2018-01-31" version="1">MFQTPQEALNYITENKIQIIDLKFIDMPGIWQHLSLFHDQIDETAFTDGVPFDGSSIRGWKAINESDMTMVIDPTTAWIDPFMAEPTLSFICSIKEPRTGEPYSRCPRTIAQKAVEYLVSTGLGDTAFFGPEAEFFIFDDVRFDQTQNSGYYYVDSVEGRWNSGKEEPGGNLGYKPRYKEGYFPVAPTDTSQDMRTEMLLTMAKCGVPIEKHHHEVATGGQCELGFRFDTLVKAADYLLTYKYVIKNVGKKYGKTITFMPKPLFNDNGSGMHVHQSIWKDGQPLFAGDQYAGFSQMGLHYIGGILKHAPALLALTNPTTNSYKRLVPGFEAPVNLAYSQGNRSASVRIPLSGTNPKAKRLEFRCPDASSNPYLAFAAMLCAGIDGIKNQIDPGEPLDVDIYDLSPEELSKIPSTPGSLEGALEALEKDHGFLTETGVFTEDFIKTWISYKLDNEVNPMRLRPHPYEFALYYDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1V8</accession>
    <name>A0A2G4F1V8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55728">
        <property type="protein sequence ID" value="PHX55728"/>
        <property type="gene ID" value="CP500_009210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="503" mass="56554" checksum="30B7CACC5D9DE9D6" modified="2018-01-31" version="1">MQESSWQENDDRRDLNLDIPDVAPEQHKSLTSSSQVGRIFATPSDDREFNLDTKGDETVAVKLPSSASFPQKLYQGRRGKAAVVLTAIWGGTITLHLVSWGPWVVWGLTGLLWMQAFRFLFASPKPAMLPLSESNQADWPYVSLLVAAKNEEAVIARLVESICNLDYPIDCYELWAIDDNSTDGTALVLEQLTKQYPQLKVWSRGANASGGKSGALNQVLPQTRGEFVGIFDADATVTPDLLRSVVPVFSSNQVGAVQVRKSIANAPVNFWTRSQEAEMALDSFFQQQRIAIGGVGELRGNGQFMRRTALESCGGWNEETITDDLDLTLRLHLDRWDIEFLAFPAVSEEGVTNAKALWHQRNRWAEGGYQRYLDYWQLIVRNRMGIGKTWDLFGFWVSQYFLPTVALPDCLMSIVLRRMPLASPLTFLTITLSLVGMFVGLRRTRKETKFDVKRVFSTLMQSLSSTVYMLHWLLVGAVTARISVRPKQLKWVKTVHQGTANIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Z7</accession>
    <name>A0A2G4F1Z7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Putative fluoride ion transporter CrcB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">crcB</name>
        <name evidence="10" type="ORF">CP500_009150</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55765">
        <property type="protein sequence ID" value="PHX55765"/>
        <property type="gene ID" value="CP500_009150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00494">
        <property type="entry name" value="crcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="14522" checksum="2325BA3D664091E8" modified="2018-01-31" version="1">MLQDSNFRVPIAISFGAVAGALSRYYITLWFASRFSTAFPYATFLINITGCLAMGFFITLASERVMIIPLEVRLMVTTGFLGAYTTFSTYGLETNALWRDRSYSVATFYWAGSAILGVIAVQLGIILARSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F297</accession>
    <name>A0A2G4F297_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phycocyanobilin lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55865">
        <property type="protein sequence ID" value="PHX55865"/>
        <property type="gene ID" value="CP500_008515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="221" mass="24172" checksum="6E72440155D0FADB" modified="2018-01-31" version="1">MDIHEIEASLENSDFQYRLKAIAALKDYTPEIAVPLLKAKLNDPEFLVRSFVSRGFGQQKTAESFAALLQIIKLDNTPNVRAEAANSLSLFGQCAASHLVLTFIQDDHWLVRRSILGALVDMECHNEIFEVCVEALAGEDMTTQEAAVDGLGALAGTIQEQAALAQLLTLAGSEYEGIRQHTASALKHFDHPQAKAVLSQLRQDSHHRVVGAALENLLENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2A3</accession>
    <name>A0A2G4F2A3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_Tnp_1_assoc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55879">
        <property type="protein sequence ID" value="PHX55879"/>
        <property type="gene ID" value="CP500_008260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032806">
        <property type="entry name" value="YbfD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13808">
        <property type="entry name" value="DDE_Tnp_1_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1_assoc" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8648" checksum="20370368F9F6A9D2" modified="2018-01-31" version="1">MNLIEAIKAVPDHRHPRGIRHPLWLILMIILLGSCTGYWGYKPLAEFTKNHRSTLIKLFYLPSDIRYQINQQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2G4</accession>
    <name>A0A2G4F2G4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3'(2'),5'-bisphosphate nucleotidase CysQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55939">
        <property type="protein sequence ID" value="PHX55939"/>
        <property type="gene ID" value="CP500_008180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="294" mass="32274" checksum="AA900A5A2911CE47" modified="2018-01-31" version="1">MKTLEEISEIVRSIAWSASDILQSYYRQDPNTPNLDIQEQKDGPVTAADVAVNTCILDELQSALGNTEFGYLSEETYKAYLATNGQIPLPQSWVWIIDPLDGTRDFIDRTGEFAVHIALAYHGRPVLAVVAWPEQQKIYYAMKDAGAFVESRDGSAVKLQVSARNTVADLSIVTSRSHRDDRFNQLLHKLPCQNQLAVGSIGCKIATIVEQNADVYIALSGKSAPKDWDLAAPELILTEAGGRFTRFDGSALQYNRGDVSQWGGLLASNGCCHDALCGDAERILAGIDGRLFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2M5</accession>
    <name>A0A2G4F2M5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1824 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56010">
        <property type="protein sequence ID" value="PHX56010"/>
        <property type="gene ID" value="CP500_007590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014953">
        <property type="entry name" value="DUF1824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08854">
        <property type="entry name" value="DUF1824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="141" mass="15416" checksum="0EA7EF46EA35D116" modified="2018-01-31" version="1">MSTQNLTTLTLEQSQKILKDFTCLDMQSVASSLEKQELRQAILLVASLSDYQMLGVCASSTDEGFVALEAYLTALGYQPVFDPSSVASFTSAVYIKFNTLKGSYYVDSYIGTYRGVLVCCQSSEEGGISETYGHLPLDLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2W8</accession>
    <name>A0A2G4F2W8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56111">
        <property type="protein sequence ID" value="PHX56111"/>
        <property type="gene ID" value="CP500_007335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="10293" checksum="96170735267F52BF" modified="2018-01-31" version="1">MLRTWTDTHYKLEDDDWLYIAANEEQSSASLVCPGYARDGEGFSIHFTPEHLEMLEHLVTALRIIKAQQEAMLEYTYPEPQKAKHLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F381</accession>
    <name>A0A2G4F381_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Iron-sulfur cluster biosynthesis transcriptional regulator SufR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sufR</name>
        <name evidence="1" type="ORF">CP500_008105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55927">
        <property type="protein sequence ID" value="PHX55927"/>
        <property type="gene ID" value="CP500_008105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014075">
        <property type="entry name" value="SUF_FeS_clus_asmb_SufR_cyano"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02702">
        <property type="entry name" value="SufR_cyano"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="229" mass="26469" checksum="CCDE4B6ED5BCDD15" modified="2018-01-31" version="1">MMQTQQTSTKQDILQFLLKGDKATALELAESLDISPQAIRRHLKDLEAERLIQYQSVQAGMGRPQHIYELTSLGRDRFPNRYGDFAISFLDTLAETVGREQVISILRKQWQRKAMEYRRVMGTGSLQERVARLVELRRDEGYMAEWYPVEAVDDVSCHTDQGDRFVFMEHNCAISNVAETFPSVCGNELEMFAAVLPDCTVERTHWIIDGEHRCGYLIIARKEVRQRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F397</accession>
    <name>A0A2G4F397_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arsenic-transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_006605</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arsA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56229">
        <property type="protein sequence ID" value="PHX56229"/>
        <property type="gene ID" value="CP500_006605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="Anion-transp_ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040612">
        <property type="entry name" value="ArsA_HSP20-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="PTHR10803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17886">
        <property type="entry name" value="ArsA_HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArsA_ATPase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="ArsA_HSP20" evidence="3">
        <location>
            <begin position="327"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="44174" checksum="49B94F1BAC9D65DB" modified="2018-01-31" version="1">MRLILMTGKGGVGKTSVAAATGLRCAELGYKTLVLSTDPAHSLADSFDMELGHDSRQVKPNLWGAELDALRELEGNWGAVKRYITQVLRAQGLEGVQAEELAILPGMDEIFGLVRMKRHYDEGEFDVLIIDSAPTGTALRLLSLPEVGGWYMRKFYKPLQGISAALRPLVEPIFRPIAGFSLPDKEVMDAPYEFYEQIEALEKILTDNTVTSVRLVTNPEKMVIKESLRAHAYLSLYNVATDLIVANRIIPEEVTDPFFKRWKESQEQYRQEIHENFRPLPVKEVPLYSEEMCGLPALERLKETLYKDEDPSQIYYKENTIRIVQDNNQYVLELYLPGIAKDQIQLSKTGDELNVRIGNHRRNMVLPQALAALQPSGAKMEDDYLKIKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3A5</accession>
    <name>A0A2G4F3A5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF475 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56201">
        <property type="protein sequence ID" value="PHX56201"/>
        <property type="gene ID" value="CP500_006745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022493">
        <property type="entry name" value="CHP03716_TM_YkoY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03716">
        <property type="entry name" value="R_switched_YkoY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="255" mass="28124" checksum="8634D006472503B0" modified="2018-01-31" version="1">MVDQFLESSPILGVDTFLLLLVLVALEAVLSADNAIALASISKGLSEPKQQQQALNFGLIIAFVLRISLILTATWVIQYWQFELLGALYLLWLVWQHFASDADSEGEHHGPKFSSVWQAIPMIAFTDLAFSLDSVTTAIAVSDNTVIVVTGATIGIIALRFMAGLFIRWLDEYVHLESAGYITVGFVGIRLLVKVINENLVPPQWLVVSSIALIFVWGFSKRTPELIESTESLESAFQQDSEVALQEPEGQKSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3M8</accession>
    <name>A0A2G4F3M8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56370">
        <property type="protein sequence ID" value="PHX56370"/>
        <property type="gene ID" value="CP500_005875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="15"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="29170" checksum="A6BFFFFEAC4BE0FB" modified="2018-01-31" version="1">MFVTAELATSQDIPKRVIFPTGDLYSDEPPLETELHLRQIILLLQCLDWLWRDRNDFYVAGNLTIYYSQNQRKSEDFRGPDFFVVHGTDRKPRKSWVVWEEEGKYPNVIVEMLSPTTANTDREFKKKLYQDIFRTPDYFWFDPYTLEFAGFHLVDGEYQPLPENSSGHLWSQQLNLFLGIHQKKLRFFTASGELVPTPEESADSERQQKELAQQREDSERQQKEFAQQRADRLAAKLRELNIDPDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3N9</accession>
    <name>A0A2G4F3N9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56372">
        <property type="protein sequence ID" value="PHX56372"/>
        <property type="gene ID" value="CP500_005885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029464">
        <property type="entry name" value="HSDR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13588">
        <property type="entry name" value="HSDR_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSDR_N_2" evidence="1">
        <location>
            <begin position="18"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_31" evidence="2">
        <location>
            <begin position="224"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="508" mass="57635" checksum="B06E2942067FFEF6" modified="2018-01-31" version="1">MNFNPNNCRNESEVETKLIVSYLLPKLGYTPDTWHQEISFGNIRLDFLSFATQAIPIVIDADSPMSVIIEAKHPKENLDRHIRRLKRYLTSLSIRYGLITNAKEIRIYERVADDIQLVFKCAGQDIETKIDEIYALVGRDSLKFVKNQDNLELEDHKINLVSPELISEVPVQPDNSATAEPNQNQISEPEIVPVYTETKPEIQLKIKPEIKLDMVFQTTTQNTMKIIAVYHNKGGVGKTTTVVNLAAALSKQGKRVLVIDLDSQANTTFATGLVKFDDEEQDDLKDCNIFHVLQSEDGYSIAEVARKSNFCNPTIDVIPSHIDLMQYETEINNLDYSRMILIQKLAEVQNKYDIVLIDTPPSLNFYARVALNSSDYVIIPSDLKPFANQGLINVKEFIKKVNGFKKTIGKKPLEILGILPCKISTNTKFVQYSLPKRRETIPKRYGLEIMDSVIYERDDLAKCAEQFQIVGNMEIADPISVLDFKPDCIASQEFEMLALEVLEKIGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3P0</accession>
    <name>A0A2G4F3P0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2997 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56097">
        <property type="protein sequence ID" value="PHX56097"/>
        <property type="gene ID" value="CP500_007265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021375">
        <property type="entry name" value="DUF2997"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11211">
        <property type="entry name" value="DUF2997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7424" checksum="8FB8E6D8E3DB615E" modified="2018-01-31" version="1">METLEFVIYPDGRVQETVTGIIGASCAEVTAAIEAQLGVVLHQESTSEYFAQALNQSAEATTQVAFSDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3P4</accession>
    <name>A0A2G4F3P4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ureidoglycolate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_006030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-ureidoglycolate = glyoxylate + urea</text>
            <dbReference type="Rhea" id="RHEA:11304"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="4.3.2.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56341">
        <property type="protein sequence ID" value="PHX56341"/>
        <property type="gene ID" value="CP500_006030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004848">
        <property type="term" value="F:ureidoglycolate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050385">
        <property type="term" value="F:ureidoglycolate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007247">
        <property type="entry name" value="Ureidogly_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024060">
        <property type="entry name" value="Ureidoglycolate_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04115">
        <property type="entry name" value="Ureidogly_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="163" mass="18586" checksum="57B4A5F6CFF20959" modified="2018-01-31" version="1">MSESISTKRLLAQWVTPENFRSYGQVIFASFDGKSFDAEDAQLNLDNGIPRFYIMRLQGKCRKFGKITRHVECTQCLGSLDGKDWLMAVAPPGDSNEPSLEDIVAFRIPGNCFIKLDVGTWHAGPYFDADFVDFYNLELSDTNVVDHFSFDFVKKHNLEFEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3S4</accession>
    <name>A0A2G4F3S4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56434">
        <property type="protein sequence ID" value="PHX56434"/>
        <property type="gene ID" value="CP500_005360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="168" mass="17837" checksum="75AD78F41474B4CE" modified="2018-01-31" version="1">MNYLIAVLPDRMQAEAAYCALEKEGLPMKQVSILGRGYKTADEFGLIDPNQQAKKQAKLMAIWLIPFGFIAGVTFSLMTELKTFAWAGEIGDHLIGGVLGAIAGGMGSVFVGGAGGMAFGSGDALPYRNRLNAGKFLIAVKGSDDLTGKAANILQQFEPENIQGYTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F496</accession>
    <name>A0A2G4F496_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56307">
        <property type="protein sequence ID" value="PHX56307"/>
        <property type="gene ID" value="CP500_006135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12950" checksum="5A6E0AECD1EFEE23" modified="2018-01-31" version="1">MKLFATIHTDEDVSRLVATLLRARGFDVTTTSEQGMLSQLDSQQLAYAASVDRCLLTHNRVDFERLHLEYMIEGWEHSGIIVTPQKNAYEIVQRVAILLNTLTADEIANQLLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4C9</accession>
    <name>A0A2G4F4C9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PemK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56644">
        <property type="protein sequence ID" value="PHX56644"/>
        <property type="gene ID" value="CP500_004335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="11133" checksum="AD2BCF7FADFA10FE" modified="2018-01-31" version="1">MKLKKGNIVLAEFPFTDLSQKKLRPALVLWASSTIDEITICFISSQNVTSLSLDEFALNASDPEFYSTGLRVSSKVRVTRIVTLEQRLIVRRLGELGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4D9</accession>
    <name>A0A2G4F4D9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma regulatory factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56654">
        <property type="protein sequence ID" value="PHX56654"/>
        <property type="gene ID" value="CP500_004405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="37"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="16326" checksum="4DE8AE067172597D" modified="2018-01-31" version="1">MNTELHVPSDLRFLTIVENWLLSSLEVELGEHVDWPRQSNRLRLVLAEAYSNVIRHAHKDQPELPVLIRLNLKNRDIGLEIWDYGKGYEMNTYNPPHPEAKQESGYGWLIMSRLMDRVDYSLQVDGRNCLKLEASLPEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4H2</accession>
    <name>A0A2G4F4H2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56646">
        <property type="protein sequence ID" value="PHX56646"/>
        <property type="gene ID" value="CP500_004350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013706941" evidence="2">
        <location>
            <begin position="20"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="285" mass="31541" checksum="3EE3D025D2E3B913" modified="2018-01-31" version="1">MLLAICTISLLGISSQSVAQPSTNTPVPGSIKQSYGDSTKQTPISLSTPQNILTPNDTSAVQQTKKETDWVTIVVSLLSLAVSSVVAYTSSFRQANIQLCFGRNIILFPVTKIDATTSSVTIAGVGFNLPITFYNWSPQGGTIQRIRLVVSKQNHGDFYDMTWTTFVKIGSAGNFEDDNLAQPIAVKGLSSINQVIRFDWITELGGKIFDLQAGNYELRIYGWTKNTEKPSLKYQNSFTLKDEDYQTFKDSVAANLSRAIWVSLDENEKPNQLVSRNTIDRLYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4P9</accession>
    <name>A0A2G4F4P9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56726">
        <property type="protein sequence ID" value="PHX56726"/>
        <property type="gene ID" value="CP500_003700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="124" mass="13862" checksum="E88211145469BE33" modified="2018-01-31" version="1">MKNRDPLDNPELDRISLFVLLIPVIGFFPALWKLYRREGSPEHKAVSRLAIALALSWLLGHIFLEAVAISAESGTLPMLLMSSLLTTSYFIVSLGLMFRLGQRQPLWLPGISHVAEKIIGKHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4U8</accession>
    <name>A0A2G4F4U8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Riboflavin biosynthesis protein RibBA</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="12">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
                <shortName evidence="12">DHBP synthase</shortName>
                <ecNumber evidence="12">4.1.99.12</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">GTP cyclohydrolase-2</fullName>
                <ecNumber evidence="12">3.5.4.25</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">GTP cyclohydrolase II</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="12" type="primary">ribBA</name>
        <name evidence="14" type="ORF">CP500_003660</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="function">
        <text evidence="12">Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:23704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="12">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="12">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">In the C-terminal section; belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="12"/>
    <dbReference type="EC" id="3.5.4.25" evidence="12"/>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56780">
        <property type="protein sequence ID" value="PHX56780"/>
        <property type="gene ID" value="CP500_003660"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00179">
        <property type="entry name" value="RibA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01283">
        <property type="entry name" value="RibBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016299">
        <property type="entry name" value="Riboflavin_synth_RibBA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00505">
        <property type="entry name" value="ribA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 12 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydro2" evidence="13">
        <location>
            <begin position="221"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="DHBP synthase" evidence="12">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="12">
        <location>
            <begin position="37"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="12">
        <location>
            <begin position="150"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="GTP cyclohydrolase II" evidence="12">
        <location>
            <begin position="212"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for GTP cyclohydrolase activity" evidence="12">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GTP cyclohydrolase activity" evidence="12">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="264"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="307"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="site" description="Essential for DHBP synthase activity" evidence="12">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="site" description="Essential for DHBP synthase activity" evidence="12">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX56780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="584" mass="64619" checksum="6ADEB3130C56977C" modified="2018-01-31" version="1">MPNNHTSTQSFQFDSIDSALADLKAGRMLVVVDDENRENEGDLICASQFATPDNINFMAVHGRGLICLALTGDRLDRLELPLMVSKNTDNNQTAFTVSIDAVNGVSTGISAEDRARTIQVSIHPDTKPQDLRRPGHIFPLRAIDGGVLKRAGHTEASVDLSRLAGLYPSGVICEIQNPDGSMARLPELIVYAKTHNLKIISIADLISYRLKHDRFVRRETVAKLPTQFGDFMIYAYRDTQDNSEHVAVIKGDPAEFKDKPVMVRVHSECLTGDALGSVRCDCRMQLQAALKMIENAGSGVIVYLRQEGRGIGLVNKLKAYSLQDIGYDTVEANERLGFPADLRNYGVGAQILNDLGVKQIRLITNNPRKIAGLKGYGIEVVDRVPLLIEATDYNSIYLATKAEKLGHLLLQTYLVTVAIQWEETKEEGRRXGEEGEEVLIPGLQSAIANRYEHLEKLRHLAASRDLLLQEEARPVGTALFGQNSLIVHLGFDQAGLAAPDWYEQINHPYTEAIAQILSEISTWPDLQRLEFMVSAGADPLKLLQVQLDRETFPLSELVGICDRLKPQKIYSFAAIPDSALEMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4W8</accession>
    <name>A0A2G4F4W8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">(S)-8-amino-7-oxononanoate synthase BioU</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">8-amino-7-oxononanoate carboxylating dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">bioU</name>
        <name evidence="2" type="ORF">CP500_003285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">A 'suicide' enzyme that participates in biotin synthesis. Catalyzes the formation of (S)-8-amino-7-oxononanoate (DAN-carbamic acid) from (7R,8S)-8-amino-7-(carboxyamino)nonanoate (DAN), a function equivalent to the cannonical BioA reaction and the first half-reaction of BioD. The cellular requirement for biotin is thought be low enough that this single turnover enzyme supplies a sufficient amount of the cofactor. Overall it catalyzes three reactions: formation of a covalent linkage with 8-amino-7-oxononanoate to yield a BioU-DAN conjugate at the epsilon-amino group of Lys124 of BioU using NAD(P)H, carboxylation of the conjugate to form BioU-DAN-carbamic acid, and release of DAN-carbamic acid using NAD(P)+.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-8-amino-7-oxononanoate + CO2 + L-lysyl-[protein] = (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:63660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:12448"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:131803"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="ChEBI" id="CHEBI:149470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-8-amino-7-oxononanoate + H(+) + L-lysyl-[protein] + NADH = H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:63672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:16405"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="ChEBI" id="CHEBI:149472"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-8-amino-7-oxononanoate + H(+) + L-lysyl-[protein] + NADPH = H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:63664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:16405"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="ChEBI" id="CHEBI:149472"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>CO2 + H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NAD(+) = (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 3 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:63676"/>
            <dbReference type="Rhea" id="RHEA-COMP:12448"/>
            <dbReference type="Rhea" id="RHEA-COMP:16405"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:131803"/>
            <dbReference type="ChEBI" id="CHEBI:149470"/>
            <dbReference type="ChEBI" id="CHEBI:149472"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>CO2 + H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NADP(+) = (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 3 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:63668"/>
            <dbReference type="Rhea" id="RHEA-COMP:12448"/>
            <dbReference type="Rhea" id="RHEA-COMP:16405"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:131803"/>
            <dbReference type="ChEBI" id="CHEBI:149470"/>
            <dbReference type="ChEBI" id="CHEBI:149472"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">In cannonical biotin synthesis a pimeloyl-conjugate is transformed into biotin by the subsequent action of BioF, BioA, BioD and BioB. This enzyme replaces BioA and performs the first half-reaction of BioD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the BioU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56834">
        <property type="protein sequence ID" value="PHX56834"/>
        <property type="gene ID" value="CP500_003285"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00852">
        <property type="entry name" value="BioU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044262">
        <property type="entry name" value="BioU-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor and proton acceptor" evidence="1">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="20"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="197"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Allysine" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="338" mass="36088" checksum="8AA48762C49E39CB" modified="2018-01-31" version="1">MNTKKATDLINQPIRVGVLGYGGLGQAAARLLAPKREMLWVAAADQKGYAYAAEGLNSKECEAIYKSQGSLGYLESAGILCDRSIQELIQTAQGVDGYFLALPNLPNTFMASVARQFIESGWKGVLVDAIKRTSAVEQILALKDELQAAGITYMTGCGATPGLLTAAAALAAQSYAEVHSVKITFGVGIANWEAYRATIREDIAHLPGYDVPKAQAMSDAEVEALLDSTDGLLKLENMEHADDIMLELAGICDRDRVTVGGIVDTRNSKKPLSTNVQITGRTFEGKISTHTFTLGDETSMAANVCGPAFGYLKAGIMLQRKGISGLFTAAEIMPQFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F512</accession>
    <name>A0A2G4F512_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV pili twitching motility protein PilT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56840">
        <property type="protein sequence ID" value="PHX56840"/>
        <property type="gene ID" value="CP500_003320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="364" mass="39723" checksum="3BBE359FB26DFE95" modified="2018-01-31" version="1">MGLIIEDVLECLVEKGGSDIHIQAGASIFFRISGKLTPQPQFGEILSAEEVQMLIFQMLNNMQRKQLEMEWELDCAYGVKGLARFRVNVYRERGSWAACLRALASKIPNADALGVPQILRDLTERPRGMLLVTGQTGSGKTTTMAALLDLINRTRAEHILTVEDPIEYVFPNVKSLFHQRQKGEDTKSFSNALKAALREDPDVILVGEMRDLETIGLAISAAETGHMVMGTLHTNSAGATVDRILDVFPPIQQPQVRAQVSNSLVGIASQNLVVKVGGGRCCAMEIMLNTPAMSNLIREGKTPMIYSQIQMGAKLGMRTMEMALCDLYKSGKITWESGMAKASKPDELQRLIGPAPAGAKTGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F524</accession>
    <name>A0A2G4F524_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfurtransferase TusA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfur carrier protein TusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56846">
        <property type="protein sequence ID" value="PHX56846"/>
        <property type="gene ID" value="CP500_003350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UPF0033" evidence="2">
        <location>
            <begin position="16"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10636" checksum="F5C5118237C2B84E" modified="2018-01-31" version="1">MNSTSKIENLQSPDAQLDLRGTPCPINFVRTKLRLEQMAPGSVLEVWLDAGEPIEQVPDSLKMEGYQILETQLVTSDDNSGFFAMKVQRPEQEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F564</accession>
    <name>A0A2G4F564_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">clpB</name>
        <name evidence="14" type="ORF">CP500_002900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56943">
        <property type="protein sequence ID" value="PHX56943"/>
        <property type="gene ID" value="CP500_002900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 12" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="13">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="415"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX56943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="871" mass="98016" checksum="2BA5662C43F4CCC4" modified="2018-01-31" version="1">MQPNNPNQFTEKAWEALSRTPELVKAAQQQQLESEHLMKALLEQESGLAISLFNKAGVTLAKLRDRTDEFINRQPKISGSGGNVYLGRSLDTLLDRAETYRKDYGDEFISVEHLILGYIKDDRFGKNLLQEFKLDETKLKDIITQVRGNNKVTDQNPEGKYEALEKYGRDLTEAARQGKLDPVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIITGDVPQSLKDRQLISLDMGALIAGAKFRGEFEERLKAVLKEVMDSNGKVILFIDEIHTVVGAGATQGSMDAGNLLKPMLARGELRCIGATTLDEYRKYLEKDAALERRFQQVYVDQPTVEDTISILRGLKERYEVHHGVKISDNALVAAATLSTRYISDRFLPDKAIDLMDEAAAKLKMEITSKPEELDEIDRKVLQLEMERLSLQKESNAASIDRLERLEKDLANLKESQSGLNAQWQSEKGVIDSIQKIKEQIDKANIEIQKAELKYDLNRAAELKYGTLTQLQKQLQEAETKLTASQITGKTLLREEVTESDIAEIISKWTGIPISKLVESEMQKLLHLEDELHKRVIGQDEAVTAVADAIVRSRAGLADPNRPVASFIFLGPTGVGKTELAKALASYLFDTEEAIVRIDMSEYMEKHAVSRLIGAPPGYVGYDEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNIMLQILDDGRVTDAQGHTVDFKNSVIIMTSNVGSQYILDVAGDEEQMRSRVMESMRATFRPEFLNRIDEMIIFKSLTKSELRQIVLLQVKRLEKRLAERKMSLKLSESALDFLAEIGYDPVYGARPLKRGIQRELETQMAKGILRGDFVDGDTIFVDIENERLAFKRLPAQLVTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F571</accession>
    <name>A0A2G4F571_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_002790</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56922">
        <property type="protein sequence ID" value="PHX56922"/>
        <property type="gene ID" value="CP500_002790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="9">
        <location>
            <begin position="6"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="389" mass="41513" checksum="9D451397625E6D98" modified="2018-01-31" version="1">MSARPIYLDNHSTTPVDKRVLDAMLPYFTEQFGNAASISHVYGWEAEAAVKQSRQILAEAINASPEEIVFTSGATEANNLAIKGVAEAYFSKGKHIITVKTEHNAILDPCTYLEKLGFEITVLPVKSDGLIDIGDLIKAIRAETILVSVMMANNEIGVIQPIGEIAAICRGNDIIFHTDAAQAIGKIPIDVQDMNIDLMSLTAHKIYGPKGIGALYVRRNKPRVQLAPQMHGGGHERGMRSGTLYAPQIVGFAKAVELGIAEMEVETARVVNLRERLWGNLIGLGDVVLNGHATKRLPGNLNISVGGVDGQALMLGLQSAAAVSSGSACTSAKISPSHVLAAIGRSDKLAYASIRFGIGRFNTVAEIDAVSEHAIATITSLRQAQKVMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F589</accession>
    <name>A0A2G4F589_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">folK</name>
        <name evidence="9" type="ORF">CP500_003080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56871">
        <property type="protein sequence ID" value="PHX56871"/>
        <property type="gene ID" value="CP500_003080"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="8">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="17794" checksum="F832C98404CAC282" modified="2018-01-31" version="1">MKSRKCAIALGSNLGDSLTILKSAIATLNKTPGIAVKSHSSWYQTAPIGPPQPDYINACAILEVTLEPEQLLLALLEIEIKFNRIRQEKWGPRTLDLDLLLYDNLVLETSTLTLPHPRMTERAFVLVPLAEIAPGWVHPVTESAIAQLVQTADCSGVQKMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5R3</accession>
    <name>A0A2G4F5R3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hybrid sensor histidine kinase/response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_001540</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57112">
        <property type="protein sequence ID" value="PHX57112"/>
        <property type="gene ID" value="CP500_001540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="161"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="233"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="328"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="586"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="283"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="827" mass="93449" checksum="B33677251677F59A" modified="2018-01-31" version="1">MKKPVIVCIDDEPDVLNSLKIELKKAIGDRCIIETAEGGEDALELLADLQADEYEIALVLSDYIMPDIKGDELLKRIHERSPDTLTIMLTGQADLEALSNAIKYAKLYRYIPKPWQNEDLKLTVVEAVHSYLQDQKLTDEIIKRQESNLELKRVNEALSASESQLKQFLEALPMGVSVYNYDGSIAYFNRTARELLGADTIPESTAEQLAATYQLYVANSDRLYPPDNLPILRALRGEFVRVDDVEIHRNGNTVALEISTTPIFDINGNIAYAIAAFQDISDRKQAEKVIVNYQRTLEAQIQERTEQLQQAALAAEAANQAKSTFLANMSHELRTPLNAILGFAQIMEQSPNLTCENRDNLRIIHRSGEHLLTLINQALDLSKIEAGKMLIDPTKFDIYRLLDELQDMFQLRAGNQELQLIFQRCPNVPQYVQADQIKLRQVLINLLSNAIKFTPNGSILVRVNKQEETTIDQKKGDDNGYSTCLIQFEVADTGVGIPPEELDNIFTAFVQTASGQKTQKGTGLGLTISRQFVRLMGGDLTVESELEQGSIFKFKIPVSKVEVGAIPVPKINCEVIGLQANQPQYRILIVDDREDNRQLLVKMLSPIGFAVTEASNGHEAVQIWENWQPHLILMDLRMPVMDGYEATREIRARIKQRKEKLPNGVEMNILNPEFPIPKIIALTASTIEEKRSFALLVGCDDFIHKPFRKIDIFDNLNKHLRVEYIYRKNDCSVTGFSEIGERNSLSDSLSNFAMGSMPKLPAEWIDKMRQVIRSADFDLIAKTIEEIRGSHAELADILQSHLDDFDYQKIFNLITEAEELDNADEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5T5</accession>
    <name>A0A2G4F5T5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_001915</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57099">
        <property type="protein sequence ID" value="PHX57099"/>
        <property type="gene ID" value="CP500_001915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="25943" checksum="22548371DF2B1F40" modified="2018-01-31" version="1">MRILLVDDEVELTDPLSRVLTREGYMVDVAFDGATGSNLAIQGNYDLLILDWMLPRQTGLAICQELRSQGRNTPVLFLTAKDTLDDRVQGLDAGADDYLVKPFELRELLARVRALLRRPPTFDADVAVGRLQVGDLQLDYDNQLAYRGDRTIDLSEKECQLLEYLMRHPGQLLTHEQIHQHLWSETEKPSSNVLAAQIRLLRRKIEAPRESVLIHTVYGRGYRFGEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5T9</accession>
    <name>A0A2G4F5T9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <shortName evidence="5">AcCoA synthetase</shortName>
            <shortName evidence="5">Acs</shortName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetate--CoA ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Acyl-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">acs</name>
        <name evidence="5" type="synonym">acsA</name>
        <name evidence="9" type="ORF">CP500_002055</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="5">Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57085">
        <property type="protein sequence ID" value="PHX57085"/>
        <property type="gene ID" value="CP500_002055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01123">
        <property type="entry name" value="Ac_CoA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="8">
        <location>
            <begin position="34"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="6">
        <location>
            <begin position="98"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="7">
        <location>
            <begin position="543"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="5">
        <location>
            <begin position="198"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="394"/>
            <end position="396"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="418"/>
            <end position="423"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="512"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="538"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="549"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="551"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="554"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="5">
        <location>
            <position position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="656" mass="72977" checksum="F614EF400D7E9F76" modified="2018-01-31" version="1">MSQDTIESILHEKRLFQPPAEFSEKAHIKSLEEYQALYDKAKADPQAFWAELATQELDWFQKWDAVLDWQPPFAKWFVNGKINISYNCLDRHLTTWRKNKAALIWEGEPGDSRTLTYAQLHREVCQMANVIKQLGVQKGDRVGIYMPMIPEAAIAMLACARIGAVHSVVFGGFSAEALRDRLNDGQAKLVITADGGFRKDTAVGLKAQVDEALANDAAPSVTNVLVVQRTKQQIHMESGRDHWWHDLQKGVSANCPAEPMDSEDLLFILYTSGSTGKPKGVVHTTGGYNLYSHMTTKWIFDLQDTDVYWCTADVGWITGHSYIVYGPLSNGATTLMYEGAPRPSNPGCFWDVIEKYGVTIFYTAPTAIRTFMKMGEHLPNARDLSSLRLLGTVGEPINPEAWMWYQRIIGNSNCPIVDTWWQTETGGIMITALPGAIPTKPGSATLPFPGIIADVVNQDGEPVTNESGGYLVVKHPWPGMMRTLYNDADRFRRTYWEYLHPKDGEFVYFAGDGAHKDKDGYFWVMGRVDDVINVAGHRLGTMEVESALVSHPAVAEAAVVGKPDEIKGEEIVAFVTLENTQQPSDELAKELKQHVVKEIGAIARPGEIRFTDALPKTRSGKIMRRLLRSLAAGQEVTGDTSTLEDRTVLDKLRGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5W8</accession>
    <name>A0A2G4F5W8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Adenylate kinase</fullName>
            <shortName evidence="6">AK</shortName>
            <ecNumber evidence="6 8">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">adk</name>
        <name evidence="9" type="ORF">CP500_001720</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="6 8"/>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57139">
        <property type="protein sequence ID" value="PHX57139"/>
        <property type="gene ID" value="CP500_001720"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMP" evidence="6">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="21157" checksum="CDCA7CB5ACF6E2D8" modified="2018-01-31" version="1">MQLIFMGPPGAGKGTQAQLLATLWKIPHISTGDILRACVVAKTTLGQKAQAYMDAGDLVPDQLLMDIVQERMNQPDATAGWILDGFPRTVPQAAFFDTLLCDVGGGKSGKDCDLRAVNLDVPDNILVTRLLSRGRQDDNEQTIRRRLQVYREQTEPLIEFYRDRQQLVAVDGDRSMEEVTAQLQQALSVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5X0</accession>
    <name>A0A2G4F5X0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57184">
        <property type="protein sequence ID" value="PHX57184"/>
        <property type="gene ID" value="CP500_001265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="11635" checksum="8CFF0B33776786D4" modified="2018-01-31" version="1">MGNWELGIGNWASGIGNWAWGIGNWASGMGNWELGIGHRELVITKRVLANSHRVSPLTFETSTRRVFRIDFVGWVERQRNPTHCFKRVGFLITLKPALAVFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Y4</accession>
    <name>A0A2G4F5Y4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplQ</name>
        <name evidence="3" type="synonym">rpl17</name>
        <name evidence="6" type="ORF">CP500_001690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57170">
        <property type="protein sequence ID" value="PHX57170"/>
        <property type="gene ID" value="CP500_001690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="13136" checksum="60174F4895CED8EE" modified="2018-01-31" version="1">MRHRCRVPQLNKPADQRRALLRSLTTELIRHGKITTTMARAKALRSEADKMITLAKDGSLAARRQAMGFIYDKQLVHALFEAAQERYGSRNGGYTRVVRTVPRQGDNSEMAIVELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F619</accession>
    <name>A0A2G4F619_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-layer homology domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57234">
        <property type="protein sequence ID" value="PHX57234"/>
        <property type="gene ID" value="CP500_000915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="2">
        <location>
            <begin position="35"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="2">
        <location>
            <begin position="100"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="2">
        <location>
            <begin position="163"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="493" mass="55420" checksum="53DEA816964DC8A9" modified="2018-01-31" version="1">MVRSQKWQTFIALVVALGIILGNWVFPGLNTGPAFAQAKFKDVKDHWAQACIEELAEKKIITGYYEDGSFRPSRPVSRAEFAAMLRKAFPDAKTVRNPISFVDIPTTYWGFKVIREAYQTGFLSGYSGSIFNPTLNIPRWQVLVALSSGLKYSPAGQAAEILDATFEDARAIPELARNAIAAAAEKQLVVNYPAVKQLEPTRNATRAEVATFLCQAIAKPGQTALVPSQYIAQVPPDMGLPKTTEISESGKIRAEVSFVKEEENAKNIRIKIIRDGQASLEETVLIPTRSLVDNPDKKASEEVSEGRLLSLRVRDLDGDKEPEVLADLVSTKSGVRCCNYSFIYRYEPATKKYTHIKHFWGNVSYEIVDYGKNDLPKFKSLDGRFSEAFTNYADSRLPLQIWQYRQGKMLNVTKQYPVQVYTNSCELWLESNKRLSEDGEAKGVLAAYMANQYVLGQEMESWQLLERVYQAADRTQFFGQLREFLVSTGYASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F658</accession>
    <name>A0A2G4F658_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YqaE/Pmp3 family membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57274">
        <property type="protein sequence ID" value="PHX57274"/>
        <property type="gene ID" value="CP500_001140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="276" mass="32270" checksum="B0CBD96C0A51F75D" modified="2018-01-31" version="1">MSDRDFENDYQVAQQRHKQMANEADDLRYEALKNLNNEDYWATIDNCQNYLKLIDSLPKLAVESYCNVSCEMYSGDLVIDTASIFKILYLAYFCCDDTRILESLVCLQKCNQIIIKYRLVEPKKAKKWLEYKALLEAIRKMYFELQSDIKKYSRELQECNLIDDSLEINEEIVLAKHPNVDRKNLSYLKNYYPLLFQKKLDEIPKKEQTRFFRLFLAVVSPPLGVFFTVGLGLPFWTHVMIITFLGTLNVISNPLALLVACIIMTTHAVWVVLNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6G2</accession>
    <name>A0A2G4F6G2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57077">
        <property type="protein sequence ID" value="PHX57077"/>
        <property type="gene ID" value="CP500_002015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025979">
        <property type="entry name" value="ChrR-like_cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12973">
        <property type="entry name" value="Cupin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_7" evidence="1">
        <location>
            <begin position="109"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="207" mass="23148" checksum="93C5956F85645944" modified="2018-01-31" version="1">MEIMPDEEFNILAALRALDTIDESESRSLKEKLQESPELKSELDAFEAAVGAIAYTAPPVPVSSHLKHRLFQRIAELSPTPTEEVNSKPVIPAAENNTPSVIVRSQNVKWRKYTVSGISFANLYVDREKREHTCLMRLEAGVKFPLHRHGGVEEVFMLEGDLEVEGEVCYQGDYIRSFPDSIHGPVSHNGCLLLVKSSLDNEMIVNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6J6</accession>
    <name>A0A2G4F6J6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleotidyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57414">
        <property type="protein sequence ID" value="PHX57414"/>
        <property type="gene ID" value="CP500_000300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041633">
        <property type="entry name" value="Polbeta"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18765">
        <property type="entry name" value="Polbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Polbeta" evidence="2">
        <location>
            <begin position="27"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="270" mass="30899" checksum="508A76061AEBF08E" modified="2018-01-31" version="1">MNYPKISQTIEPQSLELRKEIALSVAQECIQLLKKNYAVTEVILFGSLAGDSPWHWASDVDLAVVGLSNPQWWKAYGELESLCPGWLKVDLVQLEDASPQLRCRILKEQPIPDNMYLALKIRIEDELIRIDQTWAVVETILAQAETLPEIVLTPSLASYVSDLYGGFERISERVAVTLDGGMPRGENWHQELLRQVAEPGGRNRPPLWEGSLLLELDDYRKFRHLVVHRYKVDLQGDRVLELAQNMQPLLVRVCAQVMVFNEWLESQVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6K3</accession>
    <name>A0A2G4F6K3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_000225</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245899">
        <property type="entry name" value="M.Tbo703ORF225P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57402">
        <property type="protein sequence ID" value="PHX57402"/>
        <property type="gene ID" value="CP500_000225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="33738" checksum="C841C65B74AFE4A4" modified="2018-01-31" version="1">MRTVDLFAGCGGLSLGFENAGFNVVAAFDYWHPAIQVYKENFQHPIFEKDLSQTDVCSFISDFNPDIIIGGPPCQDFSSAGKRDENLGRADLSLAFAKIITSIKPRWFVMENVARIQKSQILEEILETFRKSGYGLSSAVLNASYCGVPQARKRYFLIGQLDGEDGILNSYLTKHQSKTPMNVFEYLGDDLGIEYFYRHPRSYKRRGVFSIHEPSPTVRGVNRPIPKTYKKHEGDLCDIDERLRPLTTIERSYIQTFPKTFKFQGNKSDLEQMIGNAVPVKLAEYVASCILEYIQQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6K9</accession>
    <name>A0A2G4F6K9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Light-independent protochlorophyllide reductase subunit B</fullName>
            <shortName evidence="11">DPOR subunit B</shortName>
            <shortName evidence="11">LI-POR subunit B</shortName>
            <ecNumber evidence="11">1.3.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">chlB</name>
        <name evidence="14" type="ORF">CP500_000160</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2 ADP + chlorophyllide a + oxidized 2[4Fe-4S]-[ferredoxin] + 2 phosphate = 2 ATP + 2 H2O + protochlorophyllide a + reduced 2[4Fe-4S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:28202"/>
            <dbReference type="Rhea" id="RHEA-COMP:10002"/>
            <dbReference type="Rhea" id="RHEA-COMP:10004"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83348"/>
            <dbReference type="ChEBI" id="CHEBI:83350"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="1.3.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; bacteriochlorophyll biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Porphyrin-containing compound metabolism; chlorophyll biosynthesis (light-independent).</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Protochlorophyllide reductase is composed of three subunits; ChlL, ChlN and ChlB. Forms a heterotetramer of two ChlB and two ChlN subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ChlB/BchB/BchZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.7.7" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57390">
        <property type="protein sequence ID" value="PHX57390"/>
        <property type="gene ID" value="CP500_000160"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00669"/>
    <dbReference type="UniPathway" id="UPA00670"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016730">
        <property type="term" value="F:oxidoreductase activity, acting on iron-sulfur proteins as donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016636">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030494">
        <property type="term" value="P:bacteriochlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036068">
        <property type="term" value="P:light-independent chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019685">
        <property type="term" value="P:photosynthesis, dark reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00353">
        <property type="entry name" value="ChlB_BchB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013580">
        <property type="entry name" value="LI-POR_suB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000510">
        <property type="entry name" value="Nase/OxRdtase_comp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042298">
        <property type="entry name" value="P-CP_red_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005969">
        <property type="entry name" value="Protochl_reductB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016209">
        <property type="entry name" value="Protochlorophyllide_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00148">
        <property type="entry name" value="Oxidored_nitro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08369">
        <property type="entry name" value="PCP_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000163">
        <property type="entry name" value="PCP_ChlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01278">
        <property type="entry name" value="DPOR_BchB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 11" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0408">Iron</keyword>
    <keyword evidence="9 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 11" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_nitro" evidence="12">
        <location>
            <begin position="12"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="PCP_red" evidence="13">
        <location>
            <begin position="459"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="429"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX57390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="508" mass="56916" checksum="109F96FA34823B48" modified="2018-01-31" version="1">MKLAYWMYAGPAHIGTLRVATSFKNVHAIMHAPIGDDYFNVMRSMLERERDFTPVTTSVVDRHVLARGSQERVVDNITRKDREEHPDLIVLTPTCTSSILQEDLENFVERAQLEAKGDVLLADVNHYRVNELQAADRTLDQIVQFYINKARKKGDLVEAKSEKPSVNIIGMSTLGFHNQHDCTELKRLMADLGIEVNEVIPEGASVHNLKRLPRAWFNLVPYRELGMMAGEYLQKEFGTPMVDITPMGVVETARCIRKIQQVLNAQGADVDYEDFIDQQTRFVSQAAWFSRSIDCQNLTGKKAVVFGDNTHAAAMTKILAREMGIHVVWAGTYCKHDADWFREQVSEYCDEVLVTEDHGAIGDAIAKAEPSAIFGTQMERHVGKRLDIPCGVIAAPIHVQNFPIGYKPFLGYEGTNQCVDLVYNSFTLGMEDHLLEIFGGHDTKEVITKGISADSDMNWTKDGQAELNKIPGFVRGKVKRNTEKFARDRGIALINAEVLYAAKEAVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Q4</accession>
    <name>A0A2G4F6Q4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57395">
        <property type="protein sequence ID" value="PHX57395"/>
        <property type="gene ID" value="CP500_000185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="6705" checksum="2E96DC8208EA0B45" modified="2018-01-31" version="1">MPEEYKGYDRERTEHIEQRNGEVGDTEWTSSTTAAVSQAAAAAASGSLSASSSSSSDDDDSDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6V4</accession>
    <name>A0A2G4F6V4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57297">
        <property type="protein sequence ID" value="PHX57297"/>
        <property type="gene ID" value="CP500_000490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="221" mass="22558" checksum="E99A946AF088B661" modified="2018-01-31" version="1" fragment="single">MAIKQQEFYLVGEDTDDNVALEAGQLQDLSGGLATRKGNDTVSGSSDGEVVYGGKGNDSIDGGGGNDSLRGDKDEDTVIGGDGDDWLWGGQGNDSIVGGSGNDSLYGDRGIDTLTGGDGNDTFFVLLDDEIIDYITDYQNGGDRIASENGILNFDNNFTFSAGTGANGASSGDTVMIDKSSNRAIAVFLNVASSTFAASPTPTPTPTPTPTPAPTPAPTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-12-20" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2A5PAD1</accession>
    <name>A0A2A5PAD1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002610</name>
        <name evidence="2" type="ORF">CP500_015425</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54573">
        <property type="protein sequence ID" value="PHX54573"/>
        <property type="gene ID" value="CP500_015425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56996">
        <property type="protein sequence ID" value="PHX56996"/>
        <property type="gene ID" value="CP500_002610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007569">
        <property type="entry name" value="DUF559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04480">
        <property type="entry name" value="DUF559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF559" evidence="1">
        <location>
            <begin position="20"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="14481" checksum="34AD3210B7A3E03C" modified="2017-12-20" version="1">MPQLNDSNFHLPYNPKLIPIAKQLRKNPTPAEKKLWQDFLRNFPLRVLRQRPIDNFIVDFYCAALLLVIEIDGESHFTEQGKLYDAERTGILEGYGLKVVRFTNVEVLQSFDGVCGELLGLIEGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUB5</accession>
    <name>A0A2G4EUB5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">rpsD</name>
        <name evidence="6" type="synonym">rps4</name>
        <name evidence="11" type="ORF">CP500_023175</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000271">
        <property type="protein sequence ID" value="PHX53129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53129">
        <property type="protein sequence ID" value="PHX53129"/>
        <property type="gene ID" value="CP500_023175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_S4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="10">
        <location>
            <begin position="3"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="9">
        <location>
            <begin position="90"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="202" mass="23530" checksum="9D19D90148F2B906" modified="2018-01-31" version="1">MSRYRGPRLRIVRRLKDLPGLTRKTPRRDYPPGQHGQDRKKLSEYAVRLQEKQKLRFNYGVTERQLLRYVRKARRVTGSTGQVLLQFLEMRLDNTVFRMGMAPTIPSARQLVNHGHVTVNDREVNIASYQCKPGDVISVKNRERSRLMVETNLKDPGLAHLPSHLEFDKQKLVGKVNGVVEREWIALQVNELLVVEYYSRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUT6</accession>
    <name>A0A2G4EUT6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DegT/DnrJ/EryC1/StrS family aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_022210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000219">
        <property type="protein sequence ID" value="PHX53303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53303">
        <property type="protein sequence ID" value="PHX53303"/>
        <property type="gene ID" value="CP500_022210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="379" mass="41189" checksum="05CE6B24C8A1C272" modified="2018-01-31" version="1">MNNHLPKIPLVDLSLQHQPIQCQIEQAMGKIIHQGDFILGQALTEFETKFAGACGVQYGIGVGSGTDAIALGLQACGIKPGDEIILPANTFIATIIGVIQAKATPILVDCDPETALIDLAAAETAITSKTKAIIPVHLYGQMVSPTQLLDITKRYNLIIFEDAAQAHLASREGYRAGSFGKAAAFSFYPSKNLGSFGDGGMVITNDAEVARKMRTLRNYGAPSKYLHTEIGTNSRLDNLQAAILNVKLPYLEKWNRDRTLAAQHYNTLLEPLKHKGIIPIANHSNSGHIYHLYVIRVTEKSPINRNTLQAKLAENGIQTGIHYPVPCHLQPAYQKLGNPGDFPNTETLCQQILSLPMYPGLSNTQIEQVVGAIESSFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUW7</accession>
    <name>A0A2G4EUW7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000211">
        <property type="protein sequence ID" value="PHX53342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53342">
        <property type="protein sequence ID" value="PHX53342"/>
        <property type="gene ID" value="CP500_021980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="7986" checksum="EB98125EED49BC8C" modified="2018-01-31" version="1" fragment="single">HWALGIGHWALGIGHWALRIANLLVLLPITHSRCPMPHAPCPIPKFYFCSSGTTFEAMKPTILSRIKPTIPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVJ4</accession>
    <name>A0A2G4EVJ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000178">
        <property type="protein sequence ID" value="PHX53554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53554">
        <property type="protein sequence ID" value="PHX53554"/>
        <property type="gene ID" value="CP500_020855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="260" mass="27179" checksum="E272D15033CFFD89" modified="2018-01-31" version="1">MVLTVNNLSGDLTGFPVFAGGGPRFLGFATADDIDVKEGDLSSFTWGVWGLDGNDTIAGSSDDNERLLGNNGNDVIAGGGGNDIIYGGKDNDILDGNENNDVVRGDAGNDVIFGGPGNDLLRGGQGDDDLDGNDGNDFLAGDRGIDVLTGGPGADIFLVRSNDEGLGVDQADVITDFSFDEGDRIALPDGLTELDLLFPDDNLISYENDGIINDMVIRNRSNGQILGVFLNNSNFDLIGSFESASPFALAINGSQFQFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVR4</accession>
    <name>A0A2G4EVR4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_020495</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000171">
        <property type="protein sequence ID" value="PHX53625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53625">
        <property type="protein sequence ID" value="PHX53625"/>
        <property type="gene ID" value="CP500_020495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="13">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="11">
        <location>
            <begin position="159"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="12">
        <location>
            <begin position="285"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX53625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="391" mass="44420" checksum="FE291E58D6AF6152" modified="2018-01-31" version="1">MLKAFKYRIYPSSEQSILLAKSFGCARWFYNYALNLTSETYKQTGKGLSRNEIINLLPSLKKEYEWLTEAPSQALQQAALNLSSAFLNFFEGRAKYPNFKKKQNRQSIRFPQGCKLKDDTLKLPKIGDVHCQVSRQPEGTLKSVTVSVDPSGEYFVACLYDDGKDLPEKSSEGKAIGIDVGLTHYAITSDGTKHGNPKYYRKYEKKLAKRQRQLSRKLKGSSNRHKARIKVAKVHAKIVRCREDFLHKLSRKLVDENQVIVVENLAVRNMVKNHKLAKSISDAGWGQFCTMLKYKSEWAGKTYIEVDRFYPSSKTCNNCLNRVDSLSLDIRSWQCLKCGENHDRDINAAQNIRDEGLRILAVGHTVTASGGRVRPSKGTAFTRHLPVNEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVV2</accession>
    <name>A0A2G4EVV2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000173">
        <property type="protein sequence ID" value="PHX53608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53608">
        <property type="protein sequence ID" value="PHX53608"/>
        <property type="gene ID" value="CP500_020575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8805" checksum="89FA103F0527CAB3" modified="2018-01-31" version="1">MFVDIKNCHLFTAWPSSNYLTSWQKADAVEQSKNLKYSVQKLLRQKLYHAPVSLLQIKKIVEQIQRPTPHNNPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVV6</accession>
    <name>A0A2G4EVV6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53580">
        <property type="protein sequence ID" value="PHX53580"/>
        <property type="gene ID" value="CP500_020780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="18933" checksum="8C0C624739482579" modified="2018-01-31" version="1">MGLEQDRQQLFPPEKLNSSHEIDSFNSDNNELNEWLKRRALKNELEGASRTYVVCAGKVVIGYYCLANGALAQTTATGRVRRNMPNPIPVIVIGRLAVDRHWQGKGIGRALLRDAILRTLQATEIAGIRAILVHAISEEAKQFYEKCGFTASPIDPMTLMVTVNDARNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVY1</accession>
    <name>A0A2G4EVY1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000173">
        <property type="protein sequence ID" value="PHX53610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53610">
        <property type="protein sequence ID" value="PHX53610"/>
        <property type="gene ID" value="CP500_020590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="213" mass="23194" checksum="25726534645A599B" modified="2018-01-31" version="1">MSRVLIVADANIHLAEVLLAAIAKSNSLAEISIVSISELNSGGINLSEAMICPLTLDVPENLVFPGQDVFRFGANVSAARDRVQEQLQVATGDGNFWLPVVWTAKGPLYAEAIGAEADQESGELSYFQPVHLSDVWRQQLYDLAYRLLDLVNAPPASYLVQFGFVGERICFDRLWPFPAAPAIASVGVQLPDLFVCHWCCLTGAPIYDLQISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW36</accession>
    <name>A0A2G4EW36_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Octanoyltransferase</fullName>
            <ecNumber evidence="6 7">2.3.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lipoate-protein ligase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoyl/octanoyl transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipB</name>
        <name evidence="12" type="ORF">CP500_019860</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>L-lysyl-[protein] + octanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6 7">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the LipB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="6 7"/>
    <dbReference type="EMBL" id="NXIB02000158">
        <property type="protein sequence ID" value="PHX53743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53743">
        <property type="protein sequence ID" value="PHX53743"/>
        <property type="gene ID" value="CP500_019860"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="11">
        <location>
            <begin position="43"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="84"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="164"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6 8">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="6 10">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="231" mass="26180" checksum="3526F9665E788921" modified="2018-01-31" version="1">MLLPSFSQHLNSQSCWLLDWGQVPYSEAWEAQRKLVLERRENPDLPDVLILLEHPPVYTLGLGAKLEFLKFDGETVPELHRVERGGEVTYHCPGQLVGYPILNLRRHQPDLHWYLRQLEEVLLRVLDVLGLKGARVPGMTGVWVDGRKVGAIGIKVSRWITMHGFALNVCPNLEGFRQIVPCGIPDKPVGSLEQFIPGIEVDRVRAIVVAEFAEVFRVEMVRAEVSQSLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW69</accession>
    <name>A0A2G4EW69_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53774">
        <property type="protein sequence ID" value="PHX53774"/>
        <property type="gene ID" value="CP500_019690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="20"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="148"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="246" mass="28004" checksum="7546B83405A81C2E" modified="2018-01-31" version="1">MSSAELSESPLRSTVGKAGRILLLEGEDLLREMLALALQEQGYEVVVTSDGRNALPSVQGGSSYHGDSSFNLLIMDSINGLDLCRMLRHQGNPVPILIIGARGSANNCAFYLEAGSDDYLTKPFGMREFIARCRALMRRQRLGQLPQPVMLQYKSITLFPEECRVLVRGLEVKFSPKQFRLLELFMSYPRRVWSRDQLLEKIWGQDFIGDSKTVDVHIRWLREKLEIEPSQPEYIITVRGFGYRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW82</accession>
    <name>A0A2G4EW82_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Energy-coupling factor transporter transmembrane protein EcfT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019580</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000154">
        <property type="protein sequence ID" value="PHX53793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53793">
        <property type="protein sequence ID" value="PHX53793"/>
        <property type="gene ID" value="CP500_019580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="219" mass="24207" checksum="FE89C3EC2178A61B" modified="2018-01-31" version="1">MLKLSIPFQLRLSLTIVIGIGFMKMGAWLWLGIYGAIALFWSFWLRAPLRTLVQLLGTELIFLSLLVLPQGWERASFLLLRSLICLLVMNSFLLTLPPHSFGIALKGLPLPAGLQEIVLLAGQYLEILLAEVTRMKISAQLRGLSGSVGWLRYASASMIGALYLRSLDRAERVHAAMLIRGYKGSLPTESKSTPKERLWLTVAILTAAGLTMASYGHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW86</accession>
    <name>A0A2G4EW86_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cobalt transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_019585</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000154">
        <property type="protein sequence ID" value="PHX53794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53794">
        <property type="protein sequence ID" value="PHX53794"/>
        <property type="gene ID" value="CP500_019585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000041">
        <property type="term" value="P:transition metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002751">
        <property type="entry name" value="CbiM/NikMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025937">
        <property type="entry name" value="PDGLE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01891">
        <property type="entry name" value="CbiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13190">
        <property type="entry name" value="PDGLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PDGLE" evidence="8">
        <location>
            <begin position="225"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="308" mass="31326" checksum="342DECD17F0CA491" modified="2018-01-31" version="1">MHIPDGFLSPTVAVATGIASAAAIAVALNRTRASLGLRQAPIMGLTTAFVFAAQMINFPVAGGTSGHLLGGALASVVLGSPWAATLSMSTVFIIQSVLFADGGITALGANIFNMGLVGIWVGWWLLQPLQGLLGGSRNRLPLAAGIAASLSVVAASICVAIELAISGTVALNIALPAMVGIHILIGIGEGLITGGVLSYLVKVRPDLLPGEQPQLQKWLVPVIGVLLISGVLSLFASSWPDGLEAVAEQYGFKDKEAVAIENPTPFADYGVKGLEEQPIGTSIAGVLGSAVCFGTAFGIAQLVKPKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWA4</accession>
    <name>A0A2G4EWA4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Recombinase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53720">
        <property type="protein sequence ID" value="PHX53720"/>
        <property type="gene ID" value="CP500_019995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019993">
        <property type="entry name" value="RecB_nuclease_TM0106_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038720">
        <property type="entry name" value="YprB_RNase_H-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13482">
        <property type="entry name" value="RNase_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03491">
        <property type="entry name" value="TIGR03491"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_H_2" evidence="1">
        <location>
            <begin position="424"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="603" mass="68309" checksum="D672FF5EBDF57131" modified="2018-01-31" version="1">MLITDKLLLSYQRCNLRAFLDTLGDWKQLDPPSDFLLKLMRDSATYQQQALENETYQQPYYPRGDWAAGAAATLSLMQQGVDRIYRGVICQGELGKTNGETASISGIDGQYLPDIGEIPETPVHFSSSILHSSEITLVSRPHLLIKQPGDSKFGDWSYATADIWLSKRPKLDYQIIAAFHAQVLASVQGIMPENAWLMLRKKGLWAVNLYQRMPQMLEILDECIKMLENRDQPEVFISRQKCTLCGWYTACHAEAESIKHLSLLPGVTAKRYAILKVLGLTDLESLANANSDLLASYPEFVAGVAVDVVQQARSTFLNQPFVREEGSSAADFVADLMDVTDRGSAADFVADLTDVTDRGSVETAVNQLIRIPEVAGNSLVIAKIESVKTTENKSAALSLPAPILRKKPIPYSQSVFLPIAPIELYFDIEAEPELNLDYLHGVLVVDRYNNTEKYYEFLAESATEEGVAWSQFLELMWTYPIAPIFHFCDYEVKTFKRLAKLYNTPAYLWKPVLKRFVDIHKYVTQKAIMPVESYALKPIARWLGFEWRDAKANGAQCVCWYEEWLKTGDRSILEAIVRYNEDDCRATYVVKDWLTNFLLDHQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWF3</accession>
    <name>A0A2G4EWF3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000147">
        <property type="protein sequence ID" value="PHX53864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53864">
        <property type="protein sequence ID" value="PHX53864"/>
        <property type="gene ID" value="CP500_019190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="90" mass="10161" checksum="956F7CE3232B4155" modified="2018-01-31" version="1">MAVRQPIYSKEEFAQRGDSIYETQIRPLVETGNRGKIVAIDIETGAFEVDASEIAACDRLEAHHPDAQIWIVRIGSRYVRRFGGRTKISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWH0</accession>
    <name>A0A2G4EWH0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycolate oxidase iron-sulfur subunit</fullName>
            <ecNumber evidence="4">1.1.99.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-lactate + A = AH2 + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:15089"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>A + glycolate = AH2 + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:21264"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29805"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="1.1.99.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="4">Binds 2 [4Fe-4S] clusters.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.14" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000144">
        <property type="protein sequence ID" value="PHX53884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53884">
        <property type="protein sequence ID" value="PHX53884"/>
        <property type="gene ID" value="CP500_019070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012257">
        <property type="entry name" value="Glc_ox_4Fe-4S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32479:SF17">
        <property type="entry name" value="PTHR32479:SF17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000139">
        <property type="entry name" value="Glc_ox_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="469" mass="51701" checksum="2FA2965A5D0BD92F" modified="2018-01-31" version="1">MQTSEKSQIPSDNLRPAKESNFLAQNPHLQIPEIQGFDTNNPPNPKLIDTCVHCGFCLSTCPSYRILGKEMDSPRGRIYLMDAINEGEAPLNEATSQHFDTCLGCLACVTACPSGVQYDKLISATRHQVSRNQQRTFSDNVIRTLIFNLFPYPHRLRPLLVPLFIYQKLGLPKLIRKTGLLKKVFPRLAAMESILPKVTVDSFRDNLPEVIPAQGGKRYRVGVILGCVQRLLFSPVNEATVRVLTANGCEVVIPKSQGCCAALPEHQGQAEQAKTLARQMIDSFENTGVDFVIINAAGCGHTLKEYGHILADDPEYREKAEAFAANVKDVQEFLVSAGITAKLHPLVDGDLTMVYQDACHLLHGQKISSQPRQLLHKIPGVKLKEPIDAALCCGSAGVYNMLQPEVADELGVQKVENLLNTGAELIASSNPGCSLQIKKHLELQGKEVSLMHPIELLDYSIRGIKLLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWL6</accession>
    <name>A0A2G4EWL6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000150">
        <property type="protein sequence ID" value="PHX53830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53830">
        <property type="protein sequence ID" value="PHX53830"/>
        <property type="gene ID" value="CP500_019330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="163"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="258" mass="28676" checksum="749D0D9107318D3E" modified="2018-01-31" version="1" fragment="single">MDIAEVLTLADQLIFAKTGKHLDYVQDAILRGTLEDATYTQIAQEVYSSPSHVRNVGSDLWKTLSKGLKKDITKNNFRAVLENGIVYNYQSTIVEHITGENITVNKNLNVCPEKVRSPKTPQNPEPTAKQPRIDLGDAPEISTLFDRTSELTTLENWISSRTRLITILGLSGIGKTALTLQLIPQIQHEFDYIIWRSLHNAPHLASLQTDIIQSLSQQQETNPPNPPLSRGGEEIQPPYPRGGEEIKPPSLSPPLSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWR7</accession>
    <name>A0A2G4EWR7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4351 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000141">
        <property type="protein sequence ID" value="PHX53918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53918">
        <property type="protein sequence ID" value="PHX53918"/>
        <property type="gene ID" value="CP500_018950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="59"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="13793" checksum="9AFA450A1BE97E70" modified="2018-01-31" version="1" fragment="single">EKREQFERERVGALELSKAEGLAEGLAEGLAEGRVEGLAEGRVEGLAEGIQIGEQRGEQRGEQRGQINLIKRQLQRRLGELNQEIEDRLSQLSSEQLSALAEAIFDFSSLADLSSWLETNGSNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWX1</accession>
    <name>A0A2G4EWX1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_018345</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54033">
        <property type="protein sequence ID" value="PHX54033"/>
        <property type="gene ID" value="CP500_018345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009579">
        <property type="term" value="C:thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044665">
        <property type="entry name" value="E_coli_cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023222">
        <property type="entry name" value="PsbQ-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43246">
        <property type="entry name" value="PTHR43246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101112">
        <property type="entry name" value="SSF101112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0793">Thylakoid</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="3">
        <location>
            <begin position="192"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="41549" checksum="152EB46623D62855" modified="2018-01-31" version="1">MLHWSNFAIDTWKRWVKTVVLALLLFTLSLNFSSVSHAKRPSHSMPAGNAITDGRALLRFALPIDNQTVREVQISLEDIGNHIRSKRWGPISRDVRKASRLLNLRESDILESIPDAKKLEAQALVVQVKDGISLLEKAVKAKDREKVIDLKAKILGLVGEIEELMVTGFPFEVPSEYANLPQLKGRATVAVETEKGLITVVLDGYSAPVTAGNFVDLVDRGFYNGLRFIRSEESYVLQTGDPEGKEEGFIDPATGKYRNVPLEVLVRDDKEPVYGITLEDAGRYRDEPILPFSAYGTVAMARAEAEPDSGSSQFFFFLFEPELTPAGLNLLDGRYAVFGYMIEGKEVLDQLKQGDKIVSAKVIKGIENLVKPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX17</accession>
    <name>A0A2G4EX17_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease 3</fullName>
            <ecNumber evidence="6">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribonuclease III</fullName>
            <shortName evidence="6">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rnc</name>
        <name evidence="10" type="ORF">CP500_017905</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000125">
        <property type="protein sequence ID" value="PHX54095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54095">
        <property type="protein sequence ID" value="PHX54095"/>
        <property type="gene ID" value="CP500_017905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="9">
        <location>
            <begin position="12"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="8">
        <location>
            <begin position="165"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="241" mass="26674" checksum="CEC04FED5246DF83" modified="2018-01-31" version="1">MNPIYPGRQKELEKLAEKLGISNQNLIKWDLVDLALTHSSASAKANYEQLEFVGDAVVRLTASELLFEIYPDCSVGEFAAIRSILVSDRILSKIADSYGFDRYLIVASSAASDKTGTESRRADALEALLAALYLSTHTLELIRPWLDTHFKRLAMEIRSDPARQNYKAALQELTQGKYKTLPKYSVKETGTVQGGEDRFTAEVRLQEELLAEGKGRSIKAAEQAAAQAAFNKLVSQLTVDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX55</accession>
    <name>A0A2G4EX55_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000124">
        <property type="protein sequence ID" value="PHX54113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54113">
        <property type="protein sequence ID" value="PHX54113"/>
        <property type="gene ID" value="CP500_017855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="483"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="513"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="14"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="547" mass="59939" checksum="32989A87B580DD09" modified="2018-01-31" version="1" fragment="single">MQLQRQFSGQLIAIDTNTAIASGGEGRIYPIAQDSSLVAKIYHRPTDEDGDKLTVMFSMPPDAPIAAPGHASIAWPMDLLHTVGGREKIVGFVMPRVTKASPVHIFYTPKTRREQKPLFNYLYLHRTARNLAAAVNALHGCGYVIGDVNESNILVTDTALITLVDTDSFQVRDPYTGYVYRCPVGKPEFTPPELQGQTFRDIDRAPEHDLFGLAVLIFQLLMEGTHPFSGVYQGSDEPPPMEARIRSGHFPSGTKRIPYRPMPAAPPWEMLDPRLRQMFIRCFEDGHTSPSARPDAKTWVNAIREAEDALITCGKNNQHKYGNHLSRCPWCDRAKLLKGRDPFPSREAVRNGLHLQPAKKQHKKPKVAPLLGETAVRRQQQSAGLPRQLGQYQPSLLPMPMSSRTPPPTVPLTKFERIFQDASWGGVWGGLCLAAMGGIFSAIAEGGGAILGAIFVGAIWGAFFGMIWGVLAVPPNQILRRWVGILIGTLWGAFVLAAIGGVVFGAISENPTIGPAIWSGTGLGIVWGLVWASFQPPLVVPMGRVWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX83</accession>
    <name>A0A2G4EX83_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dynamin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_017725</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000121">
        <property type="protein sequence ID" value="PHX54139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54139">
        <property type="protein sequence ID" value="PHX54139"/>
        <property type="gene ID" value="CP500_017725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027094">
        <property type="entry name" value="Mitofusin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465">
        <property type="entry name" value="PTHR10465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin_N" evidence="5">
        <location>
            <begin position="50"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="748"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="811" mass="92762" checksum="A6974A16DDEABEDD" modified="2018-01-31" version="1">MTQMPPQCQNLQEQVDSLLQLLRQESSLRQQDITAVQASLKKAISPEFEIVFAGAFSAGKSMLINALLERELLYSAEGHATGTECYIAFAEPDKERVVLTFLSEFEIREQAYTLCEKLGLTTELNINQTDVVPLLSKGCNIIIEKEGGENKSELAKQAKALMLLLEGFETNRDRIHSLANATYSMEQFNFSNLKEAASYARRGSNSAVLKRVEYYCYHPLLQDGNIIIDTPGIDAPVQRDAELTYDKIESPDTSAVVCVLKAASSGEMTTEETQLMEKTRGNPGIRDRLFYIFNRIDETWYNTQLRQRLENLINSDFRDTARVYKTSGLLGFYGSLIKNTTTRDRFGLDTIFVTSRDRASVDAKLDSEFLGNSEETPQFVNEFNRYCANSGKLPPSKFRISVNSYETPNENYVRILAEQGKPLIEQLIQDSGIEDFRTAITRYLTEEKRPQLFKNLADDLEDLCIQLRKHYQTIQRNLDSQPREIEAMKAQELLRLNQELQQVGQDFREHIATEINEMIMNKCDIFDNDFRQLQSRMIRRLDELLDSFSVEAAYGRTVLTHPRNATAPLIAVLVEALYFLANQLEDILVEATASLVANFFQYLKDSVRKSEYYRLLYRLLGNDGGIEQQLDELSKRVSDALVNAAGVECDRYVRESPRFYDEDTFSIYQFRQTLQQTSQGYDCENMVDAQPAIRQLLRLDFEPKVSQTIRKTFRQTVNKTLKDHLLPMAQKQADDILQKYSQARDYVEQTLAQEAEEKIARNQRLQAENDEKIEKYDRAVSGINSCLQAMKLHESLLPAIGQNDGVVVDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXJ0</accession>
    <name>A0A2G4EXJ0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycogen debranching protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54253">
        <property type="protein sequence ID" value="PHX54253"/>
        <property type="gene ID" value="CP500_017110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7693" checksum="D8F872FA39F3B7B5" modified="2018-01-31" version="1">MIIWVNEQIDPSGILYACIACVDEIQAQECHESFEQNLSTEQKEQGWVATLRTVSAWDDVPVNALKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXN0</accession>
    <name>A0A2G4EXN0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional purine biosynthesis protein PurH</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
                <ecNumber evidence="8">2.1.2.3</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">AICAR transformylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">IMP cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">ATIC</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">IMP synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">Inosinicase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">purH</name>
        <name evidence="10" type="ORF">CP500_018945</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The IMP cyclohydrolase activity resides in the N-terminal region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PurH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.3" evidence="8"/>
    <dbReference type="EC" id="3.5.4.10" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000141">
        <property type="protein sequence ID" value="PHX53917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53917">
        <property type="protein sequence ID" value="PHX53917"/>
        <property type="gene ID" value="CP500_018945"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="514" mass="55211" checksum="AEFFF6DF39793BC4" modified="2018-01-31" version="1">MARLALLSVSNKTGLIDLARSLVEEFDFDIISSGGTAAALKAAGIPVTKVAEYTGSPEILGGRVKTLHPRIHGGILARRDVPQDITDLTENQIRAIDLVVVNLYPFEQTIAKPGVTLADAIEQIDIGGPAMLRASAKNHAHLTVLCNPEQYNTYLEELRQNGGESSLEFRQKSALETFKHTANYDTAIAAYLSSQSAETSSQPEEFNLSGKELQTLRYGENPHQAATWYQSGETPTGWTTSTILQGKELSYNNLVDLEAARRLIVEFPDTPAAAILKHTNPCGTALGTTISEAYQKAFDTDSVSAFGGIVALNRPIDAATATALTKTFLECIVAPGCEPEAEEIIKKKAKVRVLILPDLTQGPPQTVKIIAGGLLVQNSDDAVEDTSKWRVVTEKQPTAEELVELLFAWKVAKHVKSNAIVVTRNCTTIGVGAGQMNRVGSVKLALEQAGDLAKGAILASDGFFPFDDSVKTAAEAGISAIVQPGGSMRDRDSIDCANQLGLTMVFTDIRHFLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXR1</accession>
    <name>A0A2G4EXR1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S-layer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_018750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000137">
        <property type="protein sequence ID" value="PHX53947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53947">
        <property type="protein sequence ID" value="PHX53947"/>
        <property type="gene ID" value="CP500_018750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022222">
        <property type="entry name" value="DUF3747"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12565">
        <property type="entry name" value="DUF3747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013821249" evidence="2">
        <location>
            <begin position="30"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="3">
        <location>
            <begin position="231"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="3">
        <location>
            <begin position="300"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="3">
        <location>
            <begin position="370"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="432" mass="45691" checksum="5BD3389815F18117" modified="2018-01-31" version="1">MIKLPLVRTAAALASSALLTIGAMGSALAFTFDETEISQDRVIAIAQPRSFGGYQLLIIEQVSDKRQCWTESGSKPVTVDPVLVTFDFTGICGRATDSNGFSIRMGGTDLALKYTLELQKVNGDVLLMGTPIDLKGESVIIGRTNGDANGFMKITLDPAWRFAKRSYQGKVLGHFYFTTNQPAPGGIGGNTGGNTGGNTGGNTGGNTGGNTGGNTGGNTGGNTGGNTGGNTGNPSFTDIANDIYASEIKEAVSLGFVAGFAQDNTFRPKLPVTREELVSLVLESLKTIPGANIAFLKTISARPYSDVDITRWSAAKVQFARDNKIVSGYKDGTFKPTQSVTRAELMAVLRRAAEFGLSARGMKPDLIGKQQPKDFSDTQSHWAAAIVTQMSAYCSVASSLNETGNRFAPDNSAQRNYAATATLRMLKCVKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXS0</accession>
    <name>A0A2G4EXS0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53957">
        <property type="protein sequence ID" value="PHX53957"/>
        <property type="gene ID" value="CP500_018705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="11742" checksum="96ACDAE792B72293" modified="2018-01-31" version="1">MKHEYKIKSFCVIFPLDWSLGSVEHHAVEAQRRDTNRYRHLPMHEAAYKYKFDRLWAGIPPQPPKNPQMFASKTTVAVSINQSDIMAIAWAIENLSEKSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXU4</accession>
    <name>A0A2G4EXU4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54270">
        <property type="protein sequence ID" value="PHX54270"/>
        <property type="gene ID" value="CP500_017005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013928785" evidence="2">
        <location>
            <begin position="25"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="289" mass="30685" checksum="6B90DF64A7A90C41" modified="2018-01-31" version="1">MKWQQLILAFIATICLIFAGNALAQSDININNTNLIRFGGSVTVAEKQVVENAVAFGGSVTVSPNAKVVDTAIAFGGDVILKKGARVEGDAYSFGGKIVQEAGAIVGGERATFSDRHGMMYGSDRGRSSFFAHYFFSTIFRISSAVVAAILGLIILHSSPQFLPNLATKLGQHPGLTALWGIGAIVSFVFVTVFLAITLIGIPLIPLISVTAVVTALVGSLGVALFVGQRLFRNGNWSLQQQFLVGLAIVTVLTLIPFFGGLVVFLVNLFGLGIILLWQFGREKPQIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXW6</accession>
    <name>A0A2G4EXW6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54373">
        <property type="protein sequence ID" value="PHX54373"/>
        <property type="gene ID" value="CP500_016425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041669">
        <property type="entry name" value="TetR_C_15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17918">
        <property type="entry name" value="TetR_C_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="209" mass="23858" checksum="BCADD5B8938CC8A2" modified="2018-01-31" version="1">MTDGSKSTPIWRVPQQARSWERFHRILDAAADLFVEIGYESVTTDDIAARANTSVGGLYRFFPDKVAVFHALLDRYLNKLRDLSAALHTQEAMQVPLDIYINQLVDEFDRFVIANPGFRTVFVQARLISTTVAMIATFYQELAQQFTVYFADLNPALEQSHRELIATISVEVACALDILAVSRDRTFQHQVLRETKKLLIAYLIQYLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY09</accession>
    <name>A0A2G4EY09_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54409">
        <property type="protein sequence ID" value="PHX54409"/>
        <property type="gene ID" value="CP500_016330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16377">
        <property type="entry name" value="23S_rRNA_IVP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="14017" checksum="743FF40CB74F5BF2" modified="2018-01-31" version="1">MESFQQLRVYQLAEKIANEIWFIVKKWDDFAKDTMGKQIVRSADSVGANIAEGHGRYSCQDNQRFVRIARGSLNETRHWLRLAYARNLLTPEQSDRLHPLLNELSPKLNAYINSLKQKAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY43</accession>
    <name>A0A2G4EY43_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">hflX</name>
        <name evidence="8" type="ORF">CP500_015975</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54453">
        <property type="protein sequence ID" value="PHX54453"/>
        <property type="gene ID" value="CP500_015975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="7">
        <location>
            <begin position="425"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="384"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="598" mass="66175" checksum="2B19347CF332C806" modified="2018-01-31" version="1">MHTIYGNLQGLKSSQLKQIEKLYDQRLPGDRLTTTEFAQRLAAISSEIDKPLSTYINRRGQVIRVGIGTPRQTQIPPLELPRYGGGRLSGIRCIATHLKPEIPSESALTAMAIQRLDALVLLTVTGMGFQRRGGGATGYIQETYLAHLIPQKEQGNFDFSVLTSQLEEEEGSTPEAKPSIQNSQIKTQNFPWRVSEPLSLDDLADQDFLDLVEGLEAEFEEEFVARQVDADQDKVLLVGVMTQQMTLLDFEDGLAEITRLVDSAGGQVLQTVRQKRSRPHPQTVVGEGKVQEIALTAQTISANLVVFDRDLSSAQIRNLETMLGIRVVDRTEVILDIFAQRARSSEGKLQVELAQLQYTLPRLRGRGQTMSRQGGGIGTRGPGETKLETERRTIAKRIARLQQEVNQLLAHRFRLRQNRHHHEVPSIAIVGYTNAGKSTLLNLLTNSEVYAADQLFATLDPTTRRLTIPGTVPDEPLSIVLTDTVGFIRELPPALIDAFRATLEEVTDADALLHVVDLSHPAWQSQIRSVMNILADMPVTPGPAIVAFNKIDSVDGETLAIAREEFPQAVFISAAKGLGMETLRHRLGQLIEYAISSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY51</accession>
    <name>A0A2G4EY51_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DDE endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54449">
        <property type="protein sequence ID" value="PHX54449"/>
        <property type="gene ID" value="CP500_016085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="20"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="19675" checksum="03D2FA555A60AF6B" modified="2018-01-31" version="1">MAPALLTYQRLFGSGQRLRYLCQDETRLGLKTETGKVIMAFGVKPIAPVLWKRDNFWLYGVVEPLTGWHFCQEYDRLNTIGFQKFIDALSDQLGDDIALIQLDQAGAHVTSALRWPDNLIPVCQPAHSPELNPIERVWQFIKQQFKGEVFLTLGELRERVSPFSSFGLSDYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYB9</accession>
    <name>A0A2G4EYB9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-antigen polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_015845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000097">
        <property type="protein sequence ID" value="PHX54486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54486">
        <property type="protein sequence ID" value="PHX54486"/>
        <property type="gene ID" value="CP500_015845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="226"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="404"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="447" mass="49792" checksum="B8D7F7CC1EFC4038" modified="2018-01-31" version="1">MKEILREPLFLLIIVGIAVIVVLLIYQAVARDKKFGINVEKILAGIFLFAISGATGAGVMPFNKLHPAVMAGRETTAPTVIGYIAIYGAFLFILSPRLRSTLKDYLKALFITMSSDPCLALLLLMISVSALWSETIDVSLKNGLVILETTVVAIYIGKQYSWQDIYPWWRTVNLFVLLWSFVKTNGDGAGCWKGILGHKNQFSFFMAETAVLWFAFALYSPKNRRLAIVFGLLASLAVQKGCSGASKILVVILLGLWFYLSLIKKLPVQWAFVSVILFLIISIALAIVVMNNLEAIVVDGLKKDMTLTGRTEFWPQIVEKINERPLLGYGVAGFWQSWRGLENPAHTIIIVKSQFVPPHSHNGFLDLACDLGWGGLILFMFSFLNNIVKGVVYLTRAKLPEAGLPLFILTYTLMTNLTETGLFGTTSVWFWYIVMSVRLSLDISEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYF0</accession>
    <name>A0A2G4EYF0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54565">
        <property type="protein sequence ID" value="PHX54565"/>
        <property type="gene ID" value="CP500_015375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="29"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="258" mass="27832" checksum="550FB45BEB84E384" modified="2018-01-31" version="1">MLTSIQNPLVKEIRKLHSSKGRREQQLFLLEGTHLLEAACVAKHPLETVCATPEWVEQHDRLWEQICSLADRTELVSSKVLESIATTVQPDGIIATAPRTATPPPKLSTLGIALETIQDPGNLGAIVRTAAAANADGLLLSSDSADLDHPKVLRASAGAWFKLPMAVSPDLTAEVSRCKNRGMQILATVPNASLTYWEVDLRVPTLIVLGNEGSGLSAELIGLADRQIQIPLSRAVESLNVSIASALILYEAQRQRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYQ6</accession>
    <name>A0A2G4EYQ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54665">
        <property type="protein sequence ID" value="PHX54665"/>
        <property type="gene ID" value="CP500_014875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036104">
        <property type="entry name" value="BFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003729">
        <property type="entry name" value="Bi_nuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02577">
        <property type="entry name" value="DUF151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103256">
        <property type="entry name" value="SSF103256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51658">
        <property type="entry name" value="BFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BFN" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="18898" checksum="06DF261241BF8B53" modified="2018-01-31" version="1">MIEMKVAGIALDAATRSPIVLLRDATERRALPIYIGQEQAKAIISALEGHKPPRPLTHDLMVNFLEAWNLTLERIVIHSLQDNTFYAVLITRHGDIKKEIDARPSDAIALALRTNCPIWVMEEVIADASIPVDRDADEAERRAFREFISNLRPEDLIKGSGFSPGEASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ15</accession>
    <name>A0A2G4EZ15_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysS</name>
        <name evidence="14" type="ORF">CP500_014375</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54765">
        <property type="protein sequence ID" value="PHX54765"/>
        <property type="gene ID" value="CP500_014375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="13">
        <location>
            <begin position="394"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="292"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="11">
        <location>
            <begin position="272"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX54765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="521" mass="58502" checksum="108462BB0D0D26CC" modified="2018-01-31" version="1">MPLTLYNSLTRRESPFDPIEPKKVRMYCCGVTVYDYCHVGHARAYIVWDMVRRYLMWRGYDVRYVQNFTDIDDKILDRARETNSTMEAVAQCFIDEYFADMDKLNILRADEYPRATHTIDGIKRLIHELENKGYAYASSGDVYYNVRQFTDYGKLSGRKLEEMQAGASGRLETAEIEAQKKQDPSDFALWKSAKPGEPAWDSSWGKGRPGWHIECSAMVRDCLGETIDIHCGGSDLTFPHHENEIAQSEAATGKSLANYWMHNAFVTVNGKKMSKSLHNFITIRDLLKGNWSGDLESNPPAEGGHGGTAPTQEGSQNHSDNAKAVEPMAVRLFVLMAQYRSQIDFTSEAIASAKNGWQTLKEGLLFGTQHGSKLGWDIEKIDYLTEQDSTLVQQFQAAMDDDFNTPGALTVLFELAKELGKEGNVLVHQGKTETSPQLLQQKWVTLVNLAGVLGLEVQPEAETEISVGGLTDGEIEGLIQQRKDARKAKNFAEGDRIRNELKDNGVTLIDQKDGITIWHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ62</accession>
    <name>A0A2G4EZ62_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_014130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54801">
        <property type="protein sequence ID" value="PHX54801"/>
        <property type="gene ID" value="CP500_014130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="2">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="14248" checksum="D5D6F5A1C49EF294" modified="2018-01-31" version="1">MVLSVSERTFAQEVFQASTPVLVHFGAPWCGICRAIDPTLTTFESEWAGKVKLLGVNADQSFKLANTYRLTTLPTLILFEGEKVRFRFEQYQGREELRRTLDSWMLAVQNSPKIKLLQPQVAVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZA9</accession>
    <name>A0A2G4EZA9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4079 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54853">
        <property type="protein sequence ID" value="PHX54853"/>
        <property type="gene ID" value="CP500_013810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025067">
        <property type="entry name" value="DUF4079"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13301">
        <property type="entry name" value="DUF4079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="17136" checksum="D38D58B37A687A0B" modified="2018-01-31" version="1">MNLEIPQSVKVWSQFFHPVLMWVLLAISFYALYLGVQIRRTRSAEGEVKKELIKGKFNLKHHQMGSLLLALMVTGSIGGMAVTYINNGKLFVGSHLLAGLGMTAIIAISASLTPLMQKGNNVARYTHIALNVALLGLFGWQALTGVEIVQRIISKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZC1</accession>
    <name>A0A2G4EZC1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF202 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_013880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54866">
        <property type="protein sequence ID" value="PHX54866"/>
        <property type="gene ID" value="CP500_013880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="6">
        <location>
            <begin position="19"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="133" mass="14802" checksum="2B87B6AC79EB492B" modified="2018-01-31" version="1">MQVDDEKSKQQNLSWAIDRSANERTFLAWMRAAIALMGFGFVIVRLRVVQLPVQHRHAIGWKLGLIFSLVGLATVLISTKHYFTVRHQIDSDTYEPPDGMVLFFSFAVGLLGIGVIYAILAVALSSTSLLIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZH9</accession>
    <name>A0A2G4EZH9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54898">
        <property type="protein sequence ID" value="PHX54898"/>
        <property type="gene ID" value="CP500_013765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039060">
        <property type="entry name" value="Antitox_HigA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40455">
        <property type="entry name" value="PTHR40455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="78"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="14444" checksum="EE218D584C45D526" modified="2018-01-31" version="1">MNITIEKIAYGQLLAKSQPKPIVNEEDYSVALAEVEALMSQEKLSIEAETLLDLWALLIAEYEGKYYPIPAATPQDVLLHLIEVRELKQADLVGVIGSKGVVSEVVNGKRAISKAQAKALGKFFNVNSSVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZL4</accession>
    <name>A0A2G4EZL4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Photosystem II CP43 reaction center protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">PSII 43 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Protein CP-43</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">psbC</name>
        <name evidence="13" type="ORF">CP500_013425</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.</text>
    </comment>
    <comment type="cofactor">
        <text evidence="11">Binds multiple chlorophylls and provides some of the ligands for the Ca-4Mn-5O cluster of the oxygen-evolving complex. It may also provide a ligand for a Cl- that is required for oxygen evolution. PSII binds additional chlorophylls, carotenoids and specific lipids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cellular thylakoid membrane</location>
            <topology evidence="2 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the PsbB/PsbC family. PsbC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54949">
        <property type="protein sequence ID" value="PHX54949"/>
        <property type="gene ID" value="CP500_013425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045156">
        <property type="term" value="F:electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009772">
        <property type="term" value="P:photosynthetic electron transport in photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01496">
        <property type="entry name" value="PSII_PsbC_CP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000932">
        <property type="entry name" value="PS_antenna-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036001">
        <property type="entry name" value="PS_II_antenna-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005869">
        <property type="entry name" value="PSII_PsbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044900">
        <property type="entry name" value="PSII_PsbC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33180">
        <property type="entry name" value="PTHR33180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00421">
        <property type="entry name" value="PSII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161077">
        <property type="entry name" value="SSF161077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01153">
        <property type="entry name" value="psbC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="8 11" id="KW-0157">Chromophore</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="9 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX54949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="50060" checksum="A77CDD95DC5F273D" modified="2018-01-31" version="1">MVTLSNSYVSGRDQESSGFAWWSGNARLINLSGKLLGAHVAHAGLIVFWAGAMTLFEVAHFIPEKPMYEQGLILMPHVATLGWGIGPGGEVTDIFPFFVVGVLHLISSAVLGLGGIYHAIRGPEVLEEYSSFFGYDWKDKNQMTNIIGYHLILLGGGCLLLVAKAMFFGGVYDTWAPGGGDVRIITNPTLNPAVIFGYLVRSPFGGEGWIVSVNNMEDIIGGHIWLGLICIAGGVWHILTKPFGWARRALIWSGEAYLSYSLGALSLMGFIACCFVWFNNTAYPSEFYGPTGPEASQAQALTFLIRDQRLGANVGSAQGPTGLGKYLMRSPTGEIIFGGETMRFWDFQGPWLEPLRGTNGLDLNKIKNDIQPWQARRAAEYMTHAPLGSLNSVGGLATEVNAFNFTSPRSWLSCFHFVMGFFFLVGHLWHAGRARAAVAGFEKGIDRETEAVLSMPDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZQ5</accession>
    <name>A0A2G4EZQ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class V-fold PLP-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54990">
        <property type="protein sequence ID" value="PHX54990"/>
        <property type="gene ID" value="CP500_013285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="1">
        <location>
            <begin position="46"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="392" mass="43364" checksum="347E47776009133F" modified="2018-01-31" version="1">MNLENWLLDRDITFLNHGSFGACPIPVLEAQTSFREQLEREPLRFLMREFEPLLDHARNELAAFIGTSGDELAFVPNATTGVNAVLRSLSFNPGDELLTTNQEYNACRNTLDFVASRTGANVIVAEVPFPIESPEQVVEAVIKCVSPQTKLVLLDHIVSQTGLIFPIKQLVNELAQRGVDVLVDGSHAPGMIALNLEEIGAAYYTGNCHKWLCAPKGAGFLYVRRDKQDAIRPTTISHGANSPRTDKSRFQLEFDWMGTVDPSAYLCVPVAIDFMGSLLEGGWPELMAKNHALALAGRQILLDKLDLPQPCPDEMVGSMAVIQLKDAKFDAVEMSGIAPLQEALWEIFKIEVPVIPWPDANQQLVRISAQFYNSLPQYEYLAKALVELTSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZS5</accession>
    <name>A0A2G4EZS5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54697">
        <property type="protein sequence ID" value="PHX54697"/>
        <property type="gene ID" value="CP500_014655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="21208" checksum="B2EB3E46548C29A1" modified="2018-01-31" version="1">MSVKMQRRLFTLQEYHLMGESGIFGEDDRIELIEGEIVQMAAIGTRHASCVNRLARRFSLIPEYLATFGIQNPVKLTDRTEPQPDVVLLQPRADYYATAHPVPSEVLVLVEVSDSTVDYDRDVKVSIYARSLIQEVWLVDLVENCLEVYRQPSPNGYSLMLKFWRGQQVAPLAFPDFQVSVDFILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F010</accession>
    <name>A0A2G4F010_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recO</name>
        <name evidence="9" type="ORF">CP500_012540</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the RecO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55096">
        <property type="protein sequence ID" value="PHX55096"/>
        <property type="gene ID" value="CP500_012540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="SSF57863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="8">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="292" mass="31856" checksum="763BD4A4BB766FF1" modified="2018-01-31" version="1">MIRTYKATGINLKSSPLGESDRVLTVLTREFGLIRAVAPGVRKQRSTIGGRSELFVVNELLIAKGRSLDKITQAETVQSHPGLSRNLGKLASAQYLAELAIASALSDEPQEELFCLLSEHLSRLESLPDRTDTDSLTLLIAHLDQGIFHLLALAGVAPQVHVCCATRHPLTPNFTDPKWQIGFSIPSGGTFSLSELVNLEIERSQTTGSGYNLASRSPKTSASKHLTDFQINARELNALQQLGSPELAAEVIGDQAAWISVENILRQYAQYHLGCVIRSGSSIDTYLESFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F060</accession>
    <name>A0A2G4F060_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55152">
        <property type="protein sequence ID" value="PHX55152"/>
        <property type="gene ID" value="CP500_012275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="302" mass="33274" checksum="74CCCE38092507C7" modified="2018-01-31" version="1">MDEQRLAAYLELIQALLECPNGEEGDILNAHRELVDADFVQVVEAVAENMAAEGNSNAGWLQNLAAQLANSVRSTATPEEYLSFLGEVLQATGESRGNPQVVYPILQQNLDKLDLKFAQTLQNWATSKFTEGSSKKALSIAADIVNFGNLIQLLQSWATSKFTEGSSKKALSIAADIVNFGNLIQLLQSWATSKFTEGSSKKALSIAADIVNFGNLINQFPLGRRAWNLEIGIACYREALIVYTPENYPKDWAMTQNNLGNAYQNRIEGVRAANIEEAIACYRSFKSPYPRELSRRLGNDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F092</accession>
    <name>A0A2G4F092_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">Elongation factor Ts</fullName>
            <shortName evidence="5">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tsf</name>
        <name evidence="9" type="ORF">CP500_012390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55175">
        <property type="protein sequence ID" value="PHX55175"/>
        <property type="gene ID" value="CP500_012390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="8">
        <location>
            <begin position="58"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="5">
        <location>
            <begin position="82"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="219" mass="24197" checksum="AAE35EE3C959773F" modified="2018-01-31" version="1">MADIPAKLVKELRDKTGAGMMDCKKALAANEGNIETSIEWLRKKGLASAGKKGGRVASEGIVGSYIHTGGRVGVLVEVNCETDFVARREDFQALVRNIAMQIAACPNVEYVKVEDIPAEVVEREKAIEMGKDDLGNKPENIKEKIVQGRIDKRLKELCLMDQPFIRDQNISVEELVKQTIAQIGENVQVRRFVRFVLGEGIEKVEANFADEVAAQMGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0A8</accession>
    <name>A0A2G4F0A8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54877">
        <property type="protein sequence ID" value="PHX54877"/>
        <property type="gene ID" value="CP500_013650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13308" checksum="D577F05A047C3862" modified="2018-01-31" version="1">MSNESVPYHPLKIKSLKDPLFAVAYLTEIFEEEEGDLETGIMRKALRDVFEALGEPSMSADDAKLHLEKLDSLLSQSGIATIYALANWLKVLGLKLSVAVAEDEGEEESSVSAVELVEVGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0P2</accession>
    <name>A0A2G4F0P2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55308">
        <property type="protein sequence ID" value="PHX55308"/>
        <property type="gene ID" value="CP500_011425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="9985" checksum="B27E55CC9F78BB4A" modified="2018-01-31" version="1">MPVTQKKLIFVEQALRTGKMPVPQANLIFVEQALRTGKMPVPQENLIFVEQALRTGKMPVPQENLIFVEQALRTGKMPVPQENLIFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0T4</accession>
    <name>A0A2G4F0T4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_011265</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55370">
        <property type="protein sequence ID" value="PHX55370"/>
        <property type="gene ID" value="CP500_011265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="16"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="215" mass="22648" checksum="1A63F203951B2E0A" modified="2018-01-31" version="1">MIQFINRYGSEIIQRAIEHLYLVTIAIAIAIALGIPLGILITRKPQFKKTILGFANIMQTIPSLALFGLLIPVPIIGGIGDRTAIIALTLYSLLPIIRNTYTGIIGVDPAIREAGKGMGMTDWQLLFQVEIPLSMGVILAGVRVAAVIAIGLATIAAAIGAGGLGVFIFRGVATVNNQLLFAGAIPAALMALAADFGLGLIEQRLAKSDVKTMNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Y2</accession>
    <name>A0A2G4F0Y2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55422">
        <property type="protein sequence ID" value="PHX55422"/>
        <property type="gene ID" value="CP500_011065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="12169" checksum="BA83681B691CAFA3" modified="2018-01-31" version="1">MKIPKDAVIPDDKITGYLLVHKARNDKSKFLARAGFTSENPEALKAAIQSVVGVGEATEERNNEYGIFYRVVGELVGTNGINLSVVTIWLQRRIDGKFQFVTLQPFKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F110</accession>
    <name>A0A2G4F110_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55436">
        <property type="protein sequence ID" value="PHX55436"/>
        <property type="gene ID" value="CP500_010870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="226" mass="25669" checksum="36C14C405C981EF1" modified="2018-01-31" version="1">MVQKRPTFELLESILWEPNKGYFLLERHLERLERSADYFNFPLSLTEVCQALETLSMTFGTIAQKVRLTVSRDGRLTLEAQRLDHGILKIGASVGIATKPIDAQIPFLYHKTTYRLPYTMALESQPEYQDVLLWNEKGEMTESTIANMAIDTPTGLITPPLKCGLLPGTLRAQLIASGKIREELITLEDLRNTQTLFLINSIRGWIGLKKQPNQDVWKVVTLNPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F160</accession>
    <name>A0A2G4F160_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55514">
        <property type="protein sequence ID" value="PHX55514"/>
        <property type="gene ID" value="CP500_010430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7348" checksum="46BE9C85568A3EC1" modified="2018-01-31" version="1">MATTIEQIVPYQDFRNWKYEVDAESDRILTGVKDIAILAGVVKIFTPPLPLLRGGGKKFTNDLGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1I2</accession>
    <name>A0A2G4F1I2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55623">
        <property type="protein sequence ID" value="PHX55623"/>
        <property type="gene ID" value="CP500_009840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="11836" checksum="3138C50C7249AE81" modified="2018-01-31" version="1">MALKELEKQLLALTPSEKTQAIQLLVQSLSNTWQGIEKTPGVCGGKACIAGTRIPVWVMVEARRIGYSEADLLENYPTIGAADLANTWAYADAYPDEIELAIRENEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1J9</accession>
    <name>A0A2G4F1J9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55615">
        <property type="protein sequence ID" value="PHX55615"/>
        <property type="gene ID" value="CP500_009795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="223"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="263"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="303"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="343"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="383"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="463"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="543"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="583"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="623"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="702"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="752" mass="87071" checksum="5DE5F6DC93719365" modified="2018-01-31" version="1">MSTQNNRDLEIRRFISRNPQVFTQLLTFVDFSDKFTIGFVEVNFNTEADFLIEGLQNHPISQETQFEVLNFDENLRFLRDEIIKILPTIKREPNKKLVLIVRGLEKSIGKFGEYPPVLQDLNWVRDAYKKSVPHPMLFVLPDYAITRLAKFAADFWAWRSGVFLFKTTQATRDDAVARTLDSQRSFRTLETPEKQERIELLESLLMDYNPSHSGTEKNPSACSNILHQLGVAYLSQGNPIKAREYLEKALELTKESGNISLQAEVYNELGKAYEQERQFLAAMSAYQASLEISRTLGNRSGEANTLYYLGNVCQDLRDWEKAKKYYQQCLKIQQAIGDIYSQASTYQQLGWVAKEMWNLTEAERYYQQALEIFSEYGDRSGMAYSWKKLGEIERDCGNWDEAERLYRQSLEVEAELGDRSGMGYSWGVLGEIEQNRGNWNEAEQLYQQSLEVLTELGDRLWMASIWGLLGNIEQNRGNWDEAERLYRQSLEVQTELGDRSGMATSWGQWGDIERNRGNWDEAERLYRQSLELRTELGDRSGMATSWGTLGDIERNRGNWDEAERLYQESLELRTELGDRSGMANSWGTLGDIERNRGNWDEAERLYQESLELRTELGDRSGMANSWGLLGDIERNRGNWDEAERLYRQSLEVMTELGDRSGMASTYGCMGENELLRGNLDAAEQLSNQALMMAKELGMTKLMAEVHYDLARLERQRNNLELAQQHYNTAHQIFQQLGAAQYLEKIEREWESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1M7</accession>
    <name>A0A2G4F1M7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS607 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55652">
        <property type="protein sequence ID" value="PHX55652"/>
        <property type="gene ID" value="CP500_009580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="1">
        <location>
            <begin position="26"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="153" mass="17345" checksum="D12AA799F2DA8031" modified="2018-01-31" version="1">MAYIPLRKPVEFLGLHPNNLRKYADEGQIKSIKNGAGQRLYDVDSYQKDGSIGSGLNFKRKGLQALLVRFMRPDQLTIVVACRDRLCRFGFELFEFMAHQNGAEIVVLSNPVHCPESELTADLLAIFHVLSCRMHSLGSYRQKIKEDPTIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Q9</accession>
    <name>A0A2G4F1Q9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid oxidation protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55693">
        <property type="protein sequence ID" value="PHX55693"/>
        <property type="gene ID" value="CP500_009355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15690" checksum="E2E8FFC26C28C69E" modified="2018-01-31" version="1">MSAKDAFHEIVKTALQKDGWQITHDPYNLQAGTLELYIDLGAEKVVAAQKDGQKIAIEIKSFLGPSKISQFYTALGQFISYRAALQQQEADRILYLAVPSNVYDSFFTMGFIQSLIKQNQIHLIVYDIEQETIAQWQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1W5</accession>
    <name>A0A2G4F1W5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55739">
        <property type="protein sequence ID" value="PHX55739"/>
        <property type="gene ID" value="CP500_009270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="127"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="245"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="354" mass="40376" checksum="CAF77273CA9F101C" modified="2018-01-31" version="1">MQPNQQHDIEAITIVLQQIQESQNFREFETIKLPLELVQAGMSLWESTFYPEVLRQLAGADPETLEAWAIALSKTLNTQLEILNSWLPHLTTLPIPTTLKEKIGDRTSAINQIANDKSKLLQSAANWLQQEEKLQQSNSELQSLKEKARQLQEIQTELEGTNLDNLRAEITTHKATLEPEKQKLRSLQQQKADLDDQISALQRQQSILKEEINYWQSRQNRLETSTEDTVAELIILTQSQRERLSAALTQELATLEQQRTELAQQQKSYGEAQQQLQKAGEDFQKYQTATAEILTALKTHYLSNLGLGNLLPIDSQKVDVLLRNVQQILAEIDGELGTARRKHEEAQPKNTLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1X7</accession>
    <name>A0A2G4F1X7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55745">
        <property type="protein sequence ID" value="PHX55745"/>
        <property type="gene ID" value="CP500_009245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="139"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="459"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="589" mass="68192" checksum="C60D2583C9690944" modified="2018-01-31" version="1">MEEPAELTDAEIEETAAILEQLVGANLVQSRYDEDKCEDFYDLHRVIEEFLQGEYRQELPQLLESVYKFYCTGKTLDNPQTLADLQAVLEAQHFAFRLGNYTEAYYLIPNEYLRRWGYWNLSKELYEQILPYVEGDRRSYCLRELGAIQRDFGNWDLAEKYFKDALSMEEENGNKIGIATSLGMLGGIERNRGNWDEAERLYRQALEMMTELGDRARMASSWASLGYIEQCRGNWDEAERLYRQHLEVMTELGDRAGMAYCWGSLGDIERNRGNWDEAERLYRQSLALRTELGDRAGMATSWGLLGDIERLRGNWDEAEQFKRQSFQLRQELGDREGMASSWGAWGDIERERGNWDEAERLYRQSLALRTELGDRAGMATSWGLLGDIERLRGNWDEAEQFKRQSFQLRQELGDREGMASSWGAWGDIERERGNWDEAERLYRQSLALRTELGDRAGMASSWGLLGDIERNRGNWDEAERLFRQSLALRTELGDREGMATSIGCLGEIEMLRGNLDVAEPLLKECLAKLTELKQPSKIAEANYDLARLHRQRGNTVVAQQHYDTAHGIFQQLGAAKDLERIEKEWHNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Y0</accession>
    <name>A0A2G4F1Y0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_008830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55783">
        <property type="protein sequence ID" value="PHX55783"/>
        <property type="gene ID" value="CP500_008830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="130"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="196"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="280"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="PHYTOCHROME_2" evidence="4">
        <location>
            <begin position="397"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="583"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="347"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="538"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="818" mass="92365" checksum="F1AA76D68F06914B" modified="2018-01-31" version="1">MALYHQPFYSSALEQAIDRYPLTAGPDTSLVVAIALMSQLQNSCPLVKTTLPSDRGVMHELPPADKMRARCVLVVHNQQMIGAGNLSDHPSRGLLIGIFTPADLVRLIASGKIDTQKKVALHKIPISEVMSPVSVSLTESDDQDVFAALSLFRQHGIRYLPIVNQFRHLVGVLTRERIRQVLQPSNILKLRRVAELMTTPITAPHTSSLLTIAELMSQHQVSSVVITKNKEVTMEKPTNDHTSIFHYSFQQPLGIITEYDIVQAQFLELDFEQTFASQVMVTPLKLIKPADSLWQAHKQMQQEQVQRLVVCGGRAELLGIITQTSLLRVLDPTEMYRVVKQLQHSVYQLQAEKVELLESRNTKLEQQVRERTAKLHEQVQHDRLLTQIALRIHQSLNLEEILNASVDEVRQVLQADRVVILHLESSNSGIVVAESVAENWSSILGEIFPDTMWQEGESLLEEQIYAVPHIDQANLNPEKYARFQKAEIKAYLVVPILQDGNLWGVMCVHQCSESRQWQTSEIDLLLQLATQIAIAIQQAQLYQQVQNLNTDLERQVEERTAELQQKVHELQQLNVIKDEFLSTVSHELRTPLANMKMAIHMLKVSPMLDRRQVYLEILEAECTRETDLINALLDLQRLEAGACAIDLEPVNLQIWLPTIIEPFYTRAQNRNQHLRVDFVSKLPTLNSNRASLGRILAELLNNACKYTANDGEIALRVECTGAKKGRVKRKQGSVLNSEIQFTLSNESEIPSSELPRIFDKFYRVPNADPWKQGGTGLGLALAQKLVEQLDGKIEVESGNGNTTFTLTFPIGQDREVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Z3</accession>
    <name>A0A2G4F1Z3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55780">
        <property type="protein sequence ID" value="PHX55780"/>
        <property type="gene ID" value="CP500_009015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="71"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="455"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="580" mass="66751" checksum="CA5A94FEA3EE06C1" modified="2018-01-31" version="1">MLYLAEVQKQRSGFGLGGGKAELKLLACQRGEHNWSAVPGDDPIPVEEANKFNDGTLVLVELSASKQVQRIQEAARQLVSILQNFSRLQDKFKDKEEEIEQWKASLTFSSQELNRREMEMQAREEQLAQMVDELERLEAQRSEIENTRDEANRLRKEVDRSRAQMETAWEQLRGEQQQMQQRQSQVQQGAVVDEQQAQRIQELMSKLSGAIASAQGVREQLNQSFDVVEAQQAILDLHWGQLEQQRGTAQQQQAEVDRLYPNIQNRWQEWYQAADALTQAKVELRGRQSTLSAKEEQVEFLSVQVRIFEALTRQVSGLAQGFSSVAREQQVNVQALEKMAVEELQGLVQHLQQDLEKVFRFVNDQEEELTLQRETIEEVQEKIQAASEYDRMALENQMTDELESYQMLNETLVGQRLRLQEREDVLKQHQAVLWKRLGTANPASRDEQRDLGPVMAQLDTVRQQQGQDLQRLEQEIGQLREAIAQIEGNVNRQTGELEGKRNEIKQLEQNLFNQKSDLGELWGRVNVYQEMLQPVQDNLSGLRQKLEAVGGELDRIQQTGEQQDQTISQLQQVISGLINC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F207</accession>
    <name>A0A2G4F207_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c biogenesis protein CcsA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ccsB</name>
        <name evidence="6" type="synonym">ccsA</name>
        <name evidence="8" type="ORF">CP500_009055</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">May interact with Ccs1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cellular thylakoid membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55775">
        <property type="protein sequence ID" value="PHX55775"/>
        <property type="gene ID" value="CP500_009055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01391">
        <property type="entry name" value="CytC_CcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017562">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="PTHR30071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03144">
        <property type="entry name" value="cytochr_II_ccsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="7">
        <location>
            <begin position="68"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="356" mass="38622" checksum="88FFFE6AD987D346" modified="2018-01-31" version="1">MDLVVLQNWLDNISFAILLSTMLVYWTGAAFPGIPYLSALGSAGMAIANLSIAALLGSRWIEAGYFPLSNLYESLFFLVWGITAIHLVAENMSRSRLVGVATSPVAMAISAFAALTLPATMQSAEPLVPALKSNWLMMHVSVMMLSYATLMVGALLAIAFLIVTRGKKIELTGSSFGTNGNRNSNYRLQRPQNPELQTIETLADSGLAFSEPSFNSSNNGLGNTAVLELATVQTSANTQSQTAEILSPQRLNLAETLDNISYRIIGLGFPLLTIGIIAGGVWANEAWGSYWSWDPKETWALITWLVFAAYLHARITRGWQGRSPAILAATGFVVVWICYLGVNLLGKGLHSYGWFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F214</accession>
    <name>A0A2G4F214_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_008860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the system for phosphate transport across the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PstS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55789">
        <property type="protein sequence ID" value="PHX55789"/>
        <property type="gene ID" value="CP500_008860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011862">
        <property type="entry name" value="Phos-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02136">
        <property type="entry name" value="ptsS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5027146802" description="Phosphate-binding protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="33"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="342" mass="37733" checksum="10B4D7CF206AC3AB" modified="2018-01-31" version="1">MNLAKKSKVFTLSIIALTIGAIGLLNSCGQVQSQESESIKIDGSSTVYPITDAMAKEYQNTNSKKASITVEFSGTGGGFKKFCAGETDISNASRPIRPEEMEACNKAGIRYYELPVAFDALTVVVNPKNDWAKDITVEELKKIWEPAAQGKITKWNQIRPNWPDRPISLYGAGKDSGTFDYFTEATVGTAKASRTDYTASEDDTVLVQGVIKDENALGYFGFSYYEDNQSQLKAVGIDRGKGAVLPSREAVEKAQYQPLARPLFIYVNYKSAQSKVELRNFVEFYMKKAPTLVSSVGYIPLPKEGYQLIYQHFYNGKVGTVFGGKAQLDSTIGELLRQQATF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F236</accession>
    <name>A0A2G4F236_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55537">
        <property type="protein sequence ID" value="PHX55537"/>
        <property type="gene ID" value="CP500_010570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="342" mass="38273" checksum="C6717A0737917600" modified="2018-01-31" version="1">MAEVPQNPAQLAEALKGFTDINFQLPDPEDEQIPDFDFDNQVDNAWKVCDRFDLQTDIWRGRILRTVRDREKKGGEGRGTGFLNWLKQREIGKSQAYSLIELAKSADTLIEQGDLDPDSIRNFSKRAFVETAKASPEVQLMVTDAAGKGDRITRREVKQLSDEWMAMNSDLLPEEVKEKASTGSLPSRYLAPLVKEMEKLSPSHQIEIQKEVAENPDVDTVKQLTSDAKNLSKYLDSAAQVQALNQSHLDMEMALEESLRVGCLGTTADVVKQAAQLEQTVVKLYTIWKRLGSLTDRLYVDTGASTPNLRLLLGCLDTLSGEKIEVDFGDGERSIRLQIISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F243</accession>
    <name>A0A2G4F243_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55812">
        <property type="protein sequence ID" value="PHX55812"/>
        <property type="gene ID" value="CP500_008625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="90"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="398" mass="45109" checksum="5421B0CC57E0489F" modified="2018-01-31" version="1">MATAILDLEISKLPPEIVVEERYSKALVLIRLHGKPIGQATVTVVGGRICGDELREILMDATGDNLWKNWFYEALEWDERGPVQAMPIATVAVCTRDRPEDLRRCLDALMLMPDDGQEYLVIDNCPATDASSQLIKNYPKIRYVREDVPGESSARNRALREAKHEFVAFTDDDAVPDPNWLRSLLRNFSDPRVTCVTGLLMPLELETEAQEWFERYSAYGQGFERRVFDGAHCNPLIVAPVGVSGSMALRKSAIDCIGLFDQALGVGTPAKCGSDSEMFARILRAGYRIVYEPRAVSWHRHRRSWEELCKLLQCYGIGVYAFWTRIFVVNREFSVPLLAFAWLRYKQIPELIASVRKQPDAVPIDLLLAQLRGCISGPMAYFASRKRLQEIKEEVISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F287</accession>
    <name>A0A2G4F287_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phycocyanin operon protein Z</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55855">
        <property type="protein sequence ID" value="PHX55855"/>
        <property type="gene ID" value="CP500_008455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="21830" checksum="11ED333E08070B31" modified="2018-01-31" version="1">MTTDALFEQLKHPNPHMRDRAMFEIADSRDENTISRLVDILDDQDVTYRRAAVKALGAIGEDAVPSVVDALLNSENVTVRGSAAKALAQIAINYPDLPFPEVGLQGLKAAINDANPVVHIAAVMALGQMGSSAFEILVESLNTTDNVAVQVAIVSALASVGDRRCVEVLTTFANDEAVDSYVRESATSSLSRLDLVMNYKRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F296</accession>
    <name>A0A2G4F296_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55894">
        <property type="protein sequence ID" value="PHX55894"/>
        <property type="gene ID" value="CP500_008340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="196"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="379" mass="41905" checksum="B7B8579DA73BF6B1" modified="2018-01-31" version="1">MRSPNYLFCFLEIFSSEGGIQSYVKDILKAYLSVTAGTNSPPTAEVLLLRDSPDCQNPFESKNLKFSYLKTDPVWLGRLNFAAKILIKLVQKRPERVFCGHINLAPLIQTLCEPLGIPYTILTYGKEVWATLPPKYQMAMSQADSIWTISRYTLDRTCCNNQLNPDKFQIVPCVVDGNIFTIGPKSEDLLAKYNLTGAKILMTVARLRSTDIYKGVDVTIQALSQIAKTFPNVKYLVIGRGDDQPRLAQLAADLGVAERVIFAGFVPTANLAAHYRLADAYVMPSQEGFGIVYLEALACGVPVLAGDADGSADPLQDGKLGWRVSHRDSEAVAVACIEMLKGEDQRCDRNFLREQTLAVFSFQSLCQSVAETFNILPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2K5</accession>
    <name>A0A2G4F2K5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Allophycocyanin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_007965</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cellular thylakoid membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55978">
        <property type="protein sequence ID" value="PHX55978"/>
        <property type="gene ID" value="CP500_007965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000081">
        <property type="entry name" value="Phycocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3 4" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="2 4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="161" mass="17997" checksum="4C0A518B16A65999" modified="2018-01-31" version="1">MSVVSQLILQADDELRYPSTGELQSIKDFFKTGEQRVRIATALSDSEKKIVDEASKKLWKKRPDFISPGGNAYGQRERALCLRDYGWYLRLITYGILAGDKEPIESIGLIGVREMYNSLGVPVPGMVEAIRCLKEASLALLNQDDAKEAAPYFDYIAQAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2L7</accession>
    <name>A0A2G4F2L7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PAS domain-containing sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_007870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55996">
        <property type="protein sequence ID" value="PHX55996"/>
        <property type="gene ID" value="CP500_007870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="160"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="242"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="291"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="363"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="416"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="488"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="558"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="776" mass="88498" checksum="4EB4815C3F13CD60" modified="2018-01-31" version="1">MFWNFLNNLLFTANYIPHGHCYLWQRELVGLHIVSDSAIALSYYSIPLSLLYFVFQRKDLPFRNIFWLFGAFILSCGTTHVMEVWTLWHPVYWLSGSLKLMTALISAYTALALIPLIPQALTLPSPTHLQTINQILQTEIAERQKIAITLLELTQVQNAILNSANYTIISTDADGIIKTFNLAAQQLLGYSLEEVVGKLTPEIIHDPLEMEQRSEVLSQELGVKIKPGFEVFVALARRGIADENEWTYIRKDGSRFPVLLSVTALYDSEANINGFLGIAQDISDRKQAEKELRELNTAMQNAVEGISRLDIEGRYVNVNRAYAHKFGYEPEEMIGMEWKPILHPDDVEMLSLAYQEMLTLGKVEVEARGVRKNGSFFYKQITMVKACDKKGIFNGYHCFMKDITERKLTERALQESESKYRQIVELAEEGIWVIDSNARTTYVNHAMARMLGYTESEMFGESLFDFMDEEAKKLANDNIDRRKQGITERHEFRLKSKDGKDVWTYMSTSPVMDEKGDLLSCCALVYNITERKDSEQQMLQLTTDLKRSNQELEQFAYVASHDLQEPLRAVTSYTQLLAQRYQGNLDTKADKYINYVVDGASRMQQLINDLLAYSRLGTRAQEFDIADCNAAVAQSLCNLQIAIAEKNAIITYESLPTVMADEFQLVQLFQNLIGNAIKFCQDVPIIHISAIIQDNEWLFSVRDNGIGIDSEYADRIFVIFGRLHSRREYLGTGIGLAMCKRIVERHSGRIWVESQSGEGATFYFTIPIVNSCSIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2P2</accession>
    <name>A0A2G4F2P2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56019">
        <property type="protein sequence ID" value="PHX56019"/>
        <property type="gene ID" value="CP500_007650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="6892" checksum="AFF9EECCAF793878" modified="2018-01-31" version="1">MRHKIWELGIGNWELGIGNWELGIVNWELGIGNWESVICYIVSGCIGIIYSDATGFDIICY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Y3</accession>
    <name>A0A2G4F2Y3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fibrillin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56134">
        <property type="protein sequence ID" value="PHX56134"/>
        <property type="gene ID" value="CP500_007030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PTHR31906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAP_fibrillin" evidence="1">
        <location>
            <begin position="4"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="21487" checksum="1A0A909888A9607C" modified="2018-01-31" version="1">MIGKSGLLEIIAGTNRGLLATASDKQAILSAIAQLEDYNPTPRPVEAAELLNGDWRLLYTTSRALLNLDGFPLLKLGQIYQCVRVAESKIYNIAELYGLPYLEGIVSVAAKFEATSERRVQVKFERSILGLRSLIGYESPVKFINEIESGKKFVAVDFGLDAREQQGWLDITYLDSDLRIGRGNEGSVFVLTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Y4</accession>
    <name>A0A2G4F2Y4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56123">
        <property type="protein sequence ID" value="PHX56123"/>
        <property type="gene ID" value="CP500_006965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="17081" checksum="BEEE2D66A27BBA68" modified="2018-01-31" version="1">MSSKKHKKRQDTEIRSQSSSARREVVNIQIPEGISFSFRYYQDDKDKFSIGGRDAKYLASLLRRLRDLSQLNAQEVINNQSKSLRCHGIVWQDTTEPNGFGIPNESALVNMPYQFQISANEYGRVHGFFSENIFYIVWLDPDHNLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F390</accession>
    <name>A0A2G4F390_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55937">
        <property type="protein sequence ID" value="PHX55937"/>
        <property type="gene ID" value="CP500_008160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="20"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="15294" checksum="D9E21411E3E11C28" modified="2018-01-31" version="1">MGPALLTYQRLFGSGQRLRYLCQDETRLGLKTETGKVIMAFGVKPYAPVLWKRDNFWLYGVVEPLSGWHFCQEYDRLNTQRFQEFIDVLSHQLGDDIALIQLDQAGAHVTSALHWPDNLIPVCQPAHSPEQGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3D3</accession>
    <name>A0A2G4F3D3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56245">
        <property type="protein sequence ID" value="PHX56245"/>
        <property type="gene ID" value="CP500_006455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="71"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="250" mass="28349" checksum="0333847BD0F43390" modified="2018-01-31" version="1">MTVSTADLKITWEKLPADFILDEEPVESIDQPLLAAALREILEIAGFIVAGILIAPNMAICATLNDQLVIKAPDWFYARNVQPLFGQEIRRSYTPNLEGEIPDIVMEFLSATPGDEYSIKPSYPPGKWFFYEQVLRVPTYAIFESSAGVLEVYQLNSSGRYEAQQPDVNGRYWVAGVGLFLGVWQGTKTERTGYWLRWWDESGQMLLWGIEMLDKERQEIAIVQQQAEQERDRSQKLAAQLRAAGIEPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3H6</accession>
    <name>A0A2G4F3H6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56285">
        <property type="protein sequence ID" value="PHX56285"/>
        <property type="gene ID" value="CP500_006390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="143" mass="16304" checksum="3D04432EC83F23A7" modified="2018-01-31" version="1">MNKILFHLAFPVSNIDQTKAFYVNGLGCQLGRESPNSVIMGICGHQIVAHVSHEPLTPQRGIYPRHFGLVFTSESDWESLLAKAQQNNLNFYQEPRRRFVGLPTEHRTFFLEDPSHNILEFKYYCEAEAIFGLSEYAEVGDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3L1</accession>
    <name>A0A2G4F3L1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-binding oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56067">
        <property type="protein sequence ID" value="PHX56067"/>
        <property type="gene ID" value="CP500_007495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="3"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="423" mass="45265" checksum="328102C5CD1859CD" modified="2018-01-31" version="1">MVHVAIIGCGIVGASIAFELSNCPKLKVTVFDKQPPAQASTGAALGVLMGVISHKTKGRNWQLRETSLQRYETLIPELEAMTGRKIPFNQQGILMLCAEGEDLSKWEKLKTTRQSQGWELEIWDLEQVRDRNPDLNLNDRIIGAIYSPQDRQVDPTALTLALVDAAKINGVNFEFGIEVKGLMGGQDAHPTTNVIPCGTGILPVAEDCGTGILPVAEDCGTGILPVAEDCGTGILPVVEDCGTGILPVAEDCGTGILPVAENFDWIIIAAGLGSSALTASLNQLVDIRPVLGQALHFRLQNPLGNSDFTPVITCDDVHIVPLGNQEYWVGATVEFSENGGEIQANAEILNGVFEKAIALCPALAAATILRKWSGLRPRPERRSAPIIDRLPGASNILIASGHYRNGVLLAPATAHTIREMILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3L4</accession>
    <name>A0A2G4F3L4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Phosphoribosylformylglycinamidine cyclo-ligase</fullName>
            <ecNumber evidence="3 12">6.3.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">AIR synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">AIRS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 12">Phosphoribosyl-aminoimidazole synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">purM</name>
        <name evidence="15" type="ORF">CP500_006155</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AIR synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.1" evidence="3 12"/>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56311">
        <property type="protein sequence ID" value="PHX56311"/>
        <property type="gene ID" value="CP500_006155"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004641">
        <property type="term" value="F:phosphoribosylformylglycinamidine cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02196">
        <property type="entry name" value="PurM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00741">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004733">
        <property type="entry name" value="PurM_cligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520">
        <property type="entry name" value="PTHR10520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00878">
        <property type="entry name" value="purM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="13">
        <location>
            <begin position="55"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="14">
        <location>
            <begin position="170"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX56311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="343" mass="36233" checksum="719A306BE277A348" modified="2018-01-31" version="1">MDYREAGVDVEAGRAFVDRISSMVKSTHRSGVLGGFGGFSGFFSVPEGLKEPIMVSGTDGVGTKLKLAHELDRHDTVGIDLVAMCVNDVLTSGAEPLFFLDYLATGKLNPEQLAAVVAGIVDGCKQAGCALLGGETAEMPGFYQAGEYDLAGFCVGIVEKSKLLDGSRVKVGDVAIGLASSGVHSNGFSLVRKIVGDLGFDWHSQPEKLGGKSLGEVLLTPTTIYVKPVLAAIKSGLDIHGMAHITGGGLPENLPRCLGANQSVKIEDCSWPSLPIFDWIAEAGDVATADMFHTFNMGIGFVLLVDRTSVDRTIQWFESQDIPAWAIGAVIDSDENHSTCQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3S7</accession>
    <name>A0A2G4F3S7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional riboflavin kinase/FMN adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.1.26</ecNumber>
            <ecNumber evidence="7">2.7.7.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CP500_005555</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RibF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="6"/>
    <dbReference type="EC" id="2.7.7.2" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56381">
        <property type="protein sequence ID" value="PHX56381"/>
        <property type="gene ID" value="CP500_005555"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0288">FMN</keyword>
    <keyword evidence="16" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="15">
        <location>
            <begin position="225"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00018483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX56381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="387" mass="41937" checksum="932350330D424DA7" modified="2018-01-31" version="1">MWITSSFTAALTPTAVALGNFDGLHLGHRQVVEPILNRSILENSGAISSSISVLQSELQTVTAKDVGWSVTQTSDKELKSWDSNGAVKLYGTVVTFNPHPQEFFSGQSKKLLTPLAEKVELLEAMGVEQLILLPFDRELAALTAPQFVEEILVRQLQASRISVGMDFRFGQGRAGTAVDLQAIASNYGIDVTLVGLHTCGEGERISSSVIRESLACGDLRRANQLLGRCYNLVGQIVQGQQLGRTIGFPTANIELPPSKFLPRFGVYAVRVLVKNGGGMIKDESSSYEWENPKSLMPGQTSDLSLINGVMNVGCRPTVDGQEPTVEVHLLDWSGDLYGQTLSVSLVEFLRPEQKFASLEALKTQIQADCDVARSVLGHRASGIGHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3W0</accession>
    <name>A0A2G4F3W0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Ferredoxin--NADP reductase</fullName>
            <shortName evidence="9">FNR</shortName>
            <ecNumber evidence="6 9">1.18.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CP500_005330</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:20125"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cellular thylakoid membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="6 9"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56428">
        <property type="protein sequence ID" value="PHX56428"/>
        <property type="gene ID" value="CP500_005330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008213">
        <property type="entry name" value="CpcD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015701">
        <property type="entry name" value="FNR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035442">
        <property type="entry name" value="FNR_plant_Cyanobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43314">
        <property type="entry name" value="PTHR43314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01383">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF501178">
        <property type="entry name" value="FNR-PetH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000361">
        <property type="entry name" value="Frd-NADP+_RD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01094">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51441">
        <property type="entry name" value="CPCD_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9 10" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 11" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CpcD-like" evidence="14">
        <location>
            <begin position="17"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="120"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="321"/>
            <end position="322"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="360"/>
            <end position="361"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000361-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX56428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="401" mass="44906" checksum="0AB3C32E06DAF422" modified="2018-01-31" version="1">MYSPSISGVATSSISGSRIFVYEVEGMRQSCETDQTSNPIRRSGSVFIAVPYDRMNQEMRRITRMGGKIVSIRPSNSAPETHGTVAPELGQQSQKSGETTKPMTQAKEKIQVPVNLYKPANPYIGKCISTEELVREGGDGTVRHVKLDISGGNLHYLEGQSIGIIPDGTDKNGKPHKIRLYSIASTRHGDNLDDKTVSLCVRRLEYKSPETGEQVFGVCSTFLTGLEPGADVKITGPVGKEMLLPDDEDATIIMMATGTGIAPFRAYLWRMFKENNPEYKFKGLAWLFFGVAYTPNILYKEELEQLQAEFPDNFRLTYAISREQKNVDGGKMYIQSRIQENADELWELVQKPKTHTYICGLKGMEGGIDEGMSAASSKYDVDWTAYQKQLKKEHRWHVETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Y6</accession>
    <name>A0A2G4F3Y6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-succinylbenzoate--CoA ligase</fullName>
            <ecNumber evidence="3">6.2.1.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.26" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56459">
        <property type="protein sequence ID" value="PHX56459"/>
        <property type="gene ID" value="CP500_005515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008756">
        <property type="term" value="F:o-succinylbenzoate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="118"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="378"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="466" mass="52496" checksum="75ECFCDF6BCC959D" modified="2018-01-31" version="1">MTENLTANILDIASRLPDNWLIGGDSREIGKICDRIFQQLTQNQPPQTPQKVFIAESEPIQFIASFIAACAAKSHIFLCNPNWVKSEWQQVFDLVQPDIILGENRLQNLTKMGFITSPTDDNKNNYQLPLIMIPSGGSSGKIRFAIHTWETLTASVQGFQQYFKLSEINSFCTLPLYHVSGLMQFMRSFTSGGKLAIQPFKDLEKCKRYDIEPEKFFISLVPTQLQQILQNPDTANWLSCFHTVLLGGAPAWPEILEIARKYQIKLALTYGMTETASQIATLKPEDFLSGNNSSGQILPHAKVTIRGSKGEILCYNKIGNIAVNTKSLALGYYPEKLVDREYCQLDDLGFFDKNNYLHIVGRNSDKIITGGENVFPIEVETAIRTTNLVADVAVIGLLDKHWGQVVTAIYVPANFEVTVKTLQAAIEDKLSKFKRPKNWILVEELPRNSQGKVNREQLQQIAMKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F467</accession>
    <name>A0A2G4F467_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56539">
        <property type="protein sequence ID" value="PHX56539"/>
        <property type="gene ID" value="CP500_004630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="179" mass="20366" checksum="49A2F5318002634A" modified="2018-01-31" version="1">MSVSVSSEKPEFKELLLQLQAAIANENTELLIQNIENSEKGVIAIFVNTLTDDNQPIIYHELKQNYELLLKAIEDKYQAELRAKDCEIALYRQEIAISQAVSKSLTQLETAANPSQKDESIAESEDVESVRAIAQQYQAELKYKDEQIALYRQEIAELRELTIILAKQPLSINIIQEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F485</accession>
    <name>A0A2G4F485_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56572">
        <property type="protein sequence ID" value="PHX56572"/>
        <property type="gene ID" value="CP500_004820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="6565" checksum="162F3FAE65998C96" modified="2018-01-31" version="1">MNTNISPILKVFTLSAALSLAIKYAGPSLSIPSTDINALIAVLSPSLIVAAILGWRAWQQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4D4</accession>
    <name>A0A2G4F4D4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system HicB family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56643">
        <property type="protein sequence ID" value="PHX56643"/>
        <property type="gene ID" value="CP500_004330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031807">
        <property type="entry name" value="HicB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15919">
        <property type="entry name" value="HicB_lk_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HicB-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7532" checksum="B26DF044D7436DDD" modified="2018-01-31" version="1">MKIKIIIHEAEEGGYWAEVPAIPGCATEGETFEELLQNLYEAIEGCLSVDIESFETNERDKIMEIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4I1</accession>
    <name>A0A2G4F4I1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Red carotenoid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the orange carotenoid-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56656">
        <property type="protein sequence ID" value="PHX56656"/>
        <property type="gene ID" value="CP500_004420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031404">
        <property type="term" value="F:chloride ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016037">
        <property type="term" value="P:light absorption"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2090.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015233">
        <property type="entry name" value="Orange_carotenoid-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036917">
        <property type="entry name" value="Orange_carotenoid-bd_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09150">
        <property type="entry name" value="Carot_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81930">
        <property type="entry name" value="SSF81930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51773">
        <property type="entry name" value="OCP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="1" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0793">Thylakoid</keyword>
    <feature type="domain" description="OCP N-terminal" evidence="2">
        <location>
            <begin position="18"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="320" mass="35137" checksum="A9196EE7123CFB30" modified="2018-01-31" version="1">MAVSIQSAQSIFSNTEIASVVPSTTDAFYKLSVEDQLALLWYAYTEMGISITAAAPGVASMALVEGILSEIKQMSAAAQSKTMFDLASNADTTIGRIYTSLRVNTKLGFWYELGQLMKQGLVAPIPAGYQMSPEATAVLETIKKLDPGQQITVLRNTVVHMGYDPDFSQEYGKRSAPRSTPTAPDQRVKTQIEGISEQTVLSYIDNMNAFDFTPAVALFAEEGALQPPFQKPIVGREAILNYMREECIGLKMMPQQGVSEPAEDGYRQVKVTGKVETPWFGSNVGMNIAWRFLLDPQGQIFFVAIDLLASPKELLNLIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4I9</accession>
    <name>A0A2G4F4I9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56682">
        <property type="protein sequence ID" value="PHX56682"/>
        <property type="gene ID" value="CP500_004095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="48" mass="5570" checksum="94A15B2AA4CB839C" modified="2018-01-31" version="1">MEQALGQYVLYRHVLNEMQSDRKLDLAISEEVFNSVFSIELGEVLLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4K9</accession>
    <name>A0A2G4F4K9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="8">IGPS</shortName>
            <ecNumber evidence="8">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpC</name>
        <name evidence="10" type="ORF">CP500_004075</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TrpC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56678">
        <property type="protein sequence ID" value="PHX56678"/>
        <property type="gene ID" value="CP500_004075"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="9">
        <location>
            <begin position="33"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="299" mass="32758" checksum="69C33C0B8F95E053" modified="2018-01-31" version="1">MLQIRRRPPSTSVSVLYLSYKIAVPDAEPQHILEEIVWQKEVEVAQKRDRTPLSELHKKLPFAPPTRDFLAALKNGKTQPAIIAEVKKASPSKGVIREDFDPVAIAKSYQENGATCISVLTDEKFFQGSFENLSKIRAAVDLPLLCKEFIIYPYQIYLARIHGADAILLIAAILSDKDLQYFVKIVKTLGMTALIEVHTQEELDRVLTLQGVNLIGINNRNLENFSVSLETTSQLLASRQTEIPAKDILIVSESGIHTPEDLAQVAMAGAGAVLIGESLVKQPDPGAALALLVADIATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F520</accession>
    <name>A0A2G4F520_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF262 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56884">
        <property type="protein sequence ID" value="PHX56884"/>
        <property type="gene ID" value="CP500_003155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="31"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="373" mass="43372" checksum="5C4FF4AFDBA82881" modified="2018-01-31" version="1">MSLQDEIDKTRQEIRTDGYSMSIGEWISLYEKSEIDIHPDFQRFFRWSDHQKSTFIESILLGIPIPPIFVSQRDDGVWDVVDGVQRLSTIYEFVGLLKKDESEKDESENNAHPVALQKTTYLASLEGKKWDDPNDKDNSFTQTQRLLIKRSKIAVNIVEKESDEMMKYELFQRLNTGGSVATPQEVRNCILLMLNKNLYQLMRTLADYEAFKKCTALSDRLYEEQYDMELVLRFILLFDQDEISLQKLGGDVSVFLTDKMREMALNKKIDYQHIETAFKTTFDLLNETTGEDSFKRYKSEQDRFLGGFLLSAYEVVALGIGYHYKIIPQINQISERIKSIWSHPTYQKWSGAGVNAARRLPYLIPLGREVFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5A0</accession>
    <name>A0A2G4F5A0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="3 12">4.1.99.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Molybdenum cofactor biosynthesis protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 15" type="primary">moaA</name>
        <name evidence="15" type="ORF">CP500_002540</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer and homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="3 12"/>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56983">
        <property type="protein sequence ID" value="PHX56983"/>
        <property type="gene ID" value="CP500_002540"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019008">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="Mob_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="14">
        <location>
            <begin position="1"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="257"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX56983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="329" mass="36744" checksum="3B0CA0A5EC5CEB8E" modified="2018-01-31" version="1">MNPVDYLRISLIDRCNFRCLYCMPEGSDLDYVLQQQLLTQSELLTLLREVFIPVGFTKFRLTGGEPLLRPGVVELVGAIASLPETRDLSMTTNGFLLAGMAENLYNAGLRRINISLDSLEPETFDKIIGSRGRSRWMQVWQGIQAAYEVGFDPLKLNVVVIPGVNDGEILELAELTINRNWHVRFIEFMPIGNGDLFGDKGWVASADLRQQISDKYGLAESGVRGNGPADVFQIPGAKGTLGFISQMSECFCDRCNRMRLSADGWLRPCLLNETGQIDLKTALRNGVSTVELRDRVRQILEIKPEINFKQRDSGTTQGNYSRTMSQIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5A9</accession>
    <name>A0A2G4F5A9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56915">
        <property type="protein sequence ID" value="PHX56915"/>
        <property type="gene ID" value="CP500_002745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="42"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="46"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="73"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="244"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="373" mass="42085" checksum="422D701C6E12343C" modified="2018-01-31" version="1">MSKWYPQQILQEPGVRISPTEKQTILRKFPPPDEKGQIYADGIFEGGGVRGVAFLGALRCCSDLGIRWRKLAGTSAGAITAAVLATDLSIDDLEELLGQLDYSIFLTKKNSPLILNGDPADDLQSPVWTLLFLTISRQMGEYSSLPFRQWLEATLAKGHLQTFADVKQVKDRELKVVISNLTRGEMLVLPDDLQRRESADSDALYEQLRLKSAEDFSVAEAVRLSMSIPLFFEPGKLGNDLIVDGGILSNFPLWIYDKQSGSTPITPRWFTFGFRLIDTGIESQIKIDSPVSMLSGMFTTMMKARDRYHQREMDKGRVINIDVTEAQVTTTDFNLDADRKAKLYRLGYLYTKRFFLSSNFSWEKHLKARGFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5C3</accession>
    <name>A0A2G4F5C3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56972">
        <property type="protein sequence ID" value="PHX56972"/>
        <property type="gene ID" value="CP500_002480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="15796" checksum="A4E9030EC71223CC" modified="2018-01-31" version="1">MKISAAMVNHYLSDITVAWFNHHELPPDEMQEYLPLVQWMKQNAINHRDLEYLKLAFEYLLTHPDVNHEDFSGGRYPYDSDDIIEIIDFIYRTIWSDSPPVSLSNSDDVQLVSISLDDWWAEREQLPELITLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5D9</accession>
    <name>A0A2G4F5D9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF561 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57023">
        <property type="protein sequence ID" value="PHX57023"/>
        <property type="gene ID" value="CP500_002210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007570">
        <property type="entry name" value="Uncharacterised_Ycf23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36895">
        <property type="entry name" value="PTHR36895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04481">
        <property type="entry name" value="DUF561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="251" mass="25915" checksum="FC53884ED682D8FD" modified="2018-01-31" version="1">MTVNPKLQRAFEQGRALKIISGLNNFDAARVAAVVKAADLGGATFVDIAADRDLVIMAKKLTNLPICVSAVEPEKFVSAVEAGADLIEIGNFDSFYASGRRFEAAEVLELTRETRSLLPHITLSVTVPHILTLDKQVQLAIELVAAGADIIQTEGGTSAQPVHAGTLGLIEKAAPTLAAAFEISRTVSIPVLCASGISNVTAPLAIGAGAAGIGVGSAVSQLNSEIAMIAAVRSLVEALAKVERSHLATSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5F1</accession>
    <name>A0A2G4F5F1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56969">
        <property type="protein sequence ID" value="PHX56969"/>
        <property type="gene ID" value="CP500_002465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="343" mass="39388" checksum="5CAD17E15FC64240" modified="2018-01-31" version="1">MKIYTFNAGSDTKVECLWSLRPNNRDRAFDKFISEFQCIEVTSIQDCDLAIFPRKAFNPESLALDNSVFDAVQEAARYSKPLVIDATCDSDSPLEIPKAAILRFGVYRSLKQDYETERPYWTNHETKKQLESLPILPRSSKPAVGFCGTTASAGKYFKIGKMLPTAISKTILSQGSWTRKVDIRLQKGMSHKLREVAIKRLTADQRIDAQFEVTNSLKDYYNPVNQNRLLLEKLFVKNMEKCDYALCVRANGNYSGRFYMTLNAGRIPLIVDTDRVFPFETQIHMVKVPVNCLDNISDFVCEHFEKTTEKEFMEMKMENRAVYNKLMAPDKYIPNFLATVNHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5G4</accession>
    <name>A0A2G4F5G4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit b'</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F(0) sector subunit b'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">ATPase subunit II</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-type ATPase subunit b'</fullName>
            <shortName evidence="11">F-ATPase subunit b'</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpF2</name>
        <name evidence="11" type="synonym">atpG</name>
        <name evidence="14" type="ORF">CP500_002510</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.</text>
    </comment>
    <comment type="function">
        <text evidence="10 11">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cellular thylakoid membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">Belongs to the ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56978">
        <property type="protein sequence ID" value="PHX56978"/>
        <property type="gene ID" value="CP500_002510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01399">
        <property type="entry name" value="ATP_synth_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034679">
        <property type="entry name" value="ATP_synth_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="3 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX56978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="161" mass="18057" checksum="1810B8CF26BE308A" modified="2018-01-31" version="1">MMHWTVLLAVEEAAKEGGLFDIDATLPLMAVQFLILVAVLNVIFYKPLTKSIEERADYIRNTQVAAKERLAKAQQLAHEYEQKLGDTRRESQKVIAVAQAEAQKSASVKVAEAQKEAQVAREKAGQEIEQQKQDAMRSLEQEVDSLSRQILEKLLGPELVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5I7</accession>
    <name>A0A2G4F5I7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cu(2+)-exporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_002175</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57016">
        <property type="protein sequence ID" value="PHX57016"/>
        <property type="gene ID" value="CP500_002175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="693"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="718"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="3"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="751" mass="80201" checksum="325220A9411B5A2F" modified="2018-01-31" version="1">MDNLTLKLQGMSCASCASSIEQAIKSVPGVIECNVNFGMEQASIQYDSQTTSLATIQEAVDAAGYKALPLPEMAADEDDSDRKNRKSESQNLQRKLWTAGIISILLVVGGIPAMTGLHLPFIPAWLHNFWLQLVLTAPVQFWCGKSFYTGAWKALKRRLATMDTLIALGTSSAYFYSVFVTLFPSFFIANGLIPSVYYEVSSSVVALILLGKTLENRAKGETSEAIRKLMGLQAKTARILRNGQELEVPLAQVEIGDVVQVRPGEQIPVDGEVIEGYSTIDEAMVTGESLPVKKQIGDEVIGSTINKMGSFKFRTTRIGKDTFLAQIVKMVQDAQGSKAPIQKLADEVTGWFVPAVIAVALATFIIWFNATGNLTLATVTMVEVLIIACPCALGLATPTAVMVGTGKGAENGILIKGAESLELAHKIQVIVLDKTGTLTEGKPTVTDFVTIKGTANSNELQLLKLAASVERNSEHPLGEAVVRYAQSQEVSLTDVQDFEAVAGSGVRGVVGGKSIALGTLRWMQELGFDTEYLELRARAWESASKTVVWMASEGKIEAILGIADALKPSSAQAVLALQKLGLEVVMLTGDNRTTAESIAHSAGIDRVFAEVRPDQKVAQIQALQAQGKIVAMVGDGINDAPALAIADVGIAIGTGTDIAIAASDITLISGDLQGIVTAIQLSRATMRNIRENLFFAFIYNIAGIPIAAGILYPMFGWLLNPIIAGGAMAFSSVSVLTNALRLRNFKPKHIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Q0</accession>
    <name>A0A2G4F5Q0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mrr_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57031">
        <property type="protein sequence ID" value="PHX57031"/>
        <property type="gene ID" value="CP500_002260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mrr_cat" evidence="2">
        <location>
            <begin position="22"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="770"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="792"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="819" mass="95286" checksum="298DEB83AAB63A0C" modified="2018-01-31" version="1">MTVNEPTIRFKIVIPNEWSNKEKGKFWEDVSADLFPKYVWEVTQNIEFAGMQTDIYVQKLDTNEKALIECKFQKRFIEAPTIYKLMGQALFKKVDSAYLLSTSDLNAKAKGVFLEYQKEQNKSYKPYDLVIWSGDKLAKKFMDVHCIEVPEIDQISGCVKTITLLLTHNKEFFWVAEEMGESNIPCRAIIFQTPKSKSYWSSEKWKKYFSLHKIWENLEITVNPIVIEAKDNLTNQSISEIPKVTVSIINQADGFDDYHRPSRPEDFFGRLEPQREFWDFVNNVRDEKTDLRVVSFSGSTGLGKSSLVLKLASDCRQKPEYKDNFYIYHVDVTSVNQEKATLFVIAAIRQALQKAIDDGFVDLPNHQVSIESVESNYFSSESIQLLIKTLKNSRKVIVIFFDQFEEILTRDSLSYLYDLFKQAAYDVDSLKENIVLGFCWRTDVNLPTTNPAYFTWHNLAKVRKDIYFSEFSQQDSSNLLDGFKKYLNSNQKGSRLQPSIKKWLLDNCKNQPWLLKRFCGDIYNQNLSISELDSKRKKVITKFDIKIIFDKDIQRANVTLEHNTCLSYIAKCSPVSKMDVCSKFNDDVINSLLKSKLVIETGQNYKIYWDMFREYLLDGKLPEMIISYRPRTKISTAWTIFRLLNQYKTISELASVSKYRDGVVVNAILDLQKFFEVTKDERGKIIVLETFIKLQDQEIAEELAELIQNHVIIKKIYEQHKPGELMWLSEFQNLLSEQYNVNPATAADYASKMLSWFHFAGLLEERNGKIVRPNNPKQGKQKGKLEKCEPQYAKQPQSTLGEGQLPLFDTSSYRSRYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Q5</accession>
    <name>A0A2G4F5Q5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsI</name>
        <name evidence="5" type="synonym">rps9</name>
        <name evidence="9" type="ORF">CP500_001675</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57133">
        <property type="protein sequence ID" value="PHX57133"/>
        <property type="gene ID" value="CP500_001675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="136" mass="15027" checksum="F5B46D560253256E" modified="2018-01-31" version="1">MQATDTGRAVYWGTGRRKCSVARVRLVPGTGVLTVNGKEGDLYLQFNPTYLALAKAPLETLGLENEYDILVKVEGGGLTGQADSIRLGVARALCQLDPDNRKPLKIEGLLTRDPRAKERKKYGLRKARKAPQYSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5R0</accession>
    <name>A0A2G4F5R0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57041">
        <property type="protein sequence ID" value="PHX57041"/>
        <property type="gene ID" value="CP500_002310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="19"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="210" mass="24088" checksum="5595F63EA18312E6" modified="2018-01-31" version="1">MKKLEVFPMTQTISKLITFDEFLEWKPENGHYELHNGVIVEMPNPTGKHSVVAGFQAFEFGLEIRRLQLPYFIPKECTIKFIDNSGYDPDVIVLDKQAVAANESRWERESVITQGDSIKLVIEVVSTNWRDDYAHKMIDYEALGISEYWIVDYLGLGGSRYIGSPKQPTLSVYQLVDGEYQIKLFRGDERVESVVFPELNLTAVQIFNGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5X5</accession>
    <name>A0A2G4F5X5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56887">
        <property type="protein sequence ID" value="PHX56887"/>
        <property type="gene ID" value="CP500_003175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="52498" checksum="0A158411605B3D53" modified="2018-01-31" version="1">MTLPNGPKTLPFVQLIQWIADPLTYMDKCASQYGDIFTTQWGNLQPFVMVNHPEAVQFMLNSSAFEAPGHLNSILKPLLGEQSMIILSGERHKRQRQLLMPPFHGERMRNYGQQICDIALDVASKWSVDRPFFARSAMQEVTMRVILQAVFGLDDGPRLQELRPLLASVVDMTGSPLRSSMLFFGWMQQDWGAWSPWGRMKQRQRKIDELIYAEIAERREQPDASRTDILSLMMAARDENGEPMTDEELRDELMTLLFAGHETTATALAWAFYWIHSLPSVRQKLLQELDSLGENPDPMEIFRLPYLSAVCQETLRIYPVGMLTFPREVKSPVELMGYQLEPGTVVVGSIYLTHRREDLYPEPLQFKPERFLERQFSPYEYVPFGGGSRRCIGMALAQLEMKLVLANILRDFDLALAENQPVQPKRRGVTLGPAGGVRMVMRGRRMRYSQKPEPVVSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F613</accession>
    <name>A0A2G4F613_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57200">
        <property type="protein sequence ID" value="PHX57200"/>
        <property type="gene ID" value="CP500_001380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="77"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="17738" checksum="55AFB31457DAA5F3" modified="2018-01-31" version="1">MSRQKASPESVLVKEPEKASIDKLEQILSRESAQPKLVGSNGEEILIPERVYSFLRQIVHGMASGQSVSVELHNPQMTTQEAAEILKVSRPFLVKLLKEGAIPYIEVGKHRRVLFQDVITYKEQRQVKRRQGMKELSQFLQEEGFYGEGVCEIAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F643</accession>
    <name>A0A2G4F643_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57226">
        <property type="protein sequence ID" value="PHX57226"/>
        <property type="gene ID" value="CP500_000850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006326">
        <property type="entry name" value="UDPGT_MGT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01426">
        <property type="entry name" value="MGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UDPGT" evidence="3">
        <location>
            <begin position="316"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="440" mass="50116" checksum="96979590F4B5596A" modified="2018-01-31" version="1">MKKHIMFVSLPFRGHASQMIVLAQELLGRGYQVSFALSEDTRDWVNNTGVIFHPWDPNLEASDLKKNYSSDSIWYQASQEQSVWRGEKMMLEEMTASYVSMYKTLKPIFSDHRPDLIVVDRAVTAAMDLSWQMKIPCIIQSRFLGNFVQTPSNLPGYGTSYSIKMNRWEKIINRLRQLWILPQFLPALKKLNQVRKDCCGCQNLPDHFSQNLIIAGTYFGIEIPRPIPPLVKMVGPIFPQKIEPISPSLKEWLEAGEEDTVVIYIAFGTLVTLEPWQAKALVEGLTHPQYRVLWSIPKPQQCCLPPLPPSFRIESFVPQQAVLSHPTIRVFVSHCGMNSINESLYFGKPILALPFLGDQYYNAARLLDLGVALKLNKKTIKSDEVRQKVDLLVKNPSYTDKANKMSAILKRTRGRELAADIIETTLDVGISHLVPELIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6B0</accession>
    <name>A0A2G4F6B0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57290">
        <property type="protein sequence ID" value="PHX57290"/>
        <property type="gene ID" value="CP500_000855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="251"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="541" mass="59625" checksum="0001A4BABD4C6B09" modified="2018-01-31" version="1">MTPTPSVTPTPTPSVTPSVTPSVTPTPTPIATPPLQLVSELTAIAPVTTTSPTAAATPAPKRASSTVDAENFQPSKALTLENPGSVADRILTIDRSITSQLPPNRPTLPQKSQQVSQVNPNSDKLLGYVPSPDRLFEQNNLEKTIWGIEQTRNQEFSEYLGVKANLPEQNVLINKFQQTLQTIEQKTGKRSGIIYLISRDEQLEIILVPPVGQPIRHSLPEAKRAALLPYVNEIRSEITNPRKLNITSYLASAQKLYKWFITPLEPDLEKLGIKTLLLSVDPGLRSLPFAALHDGKNFLVEKYNFSLIPSFSTTNTDYKSISRATVLAMGRSEFVDQNPLPNVPIELQSISTEWRGPSFLNSSFTIDNLNSQHSQGGFRIVHLATHAEFKPGQASNSYIQMWNTKLQLNHMDGLNWRNPQVELLVLSACRTVLGDREAELGFGGLAVKSGAKSALGSLWYVDDGGTLALMSEFYEQLRGVTIKTEALQLAQQAMISGKTRLENGQLVTTGGQLNLSANLQKKQNFSHPYYWSSFTMIGNPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6K4</accession>
    <name>A0A2G4F6K4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">30S ribosomal protein S1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57386">
        <property type="protein sequence ID" value="PHX57386"/>
        <property type="gene ID" value="CP500_000125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="121"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="199"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="299" mass="33139" checksum="B580630CDCF4DF84" modified="2018-01-31" version="1">MNSKSTGSQSAKASFSMDDFAKALEQHNYEFQKGQVVRGKVIEHDSNGAYVDIGGKSSAFLPIEEAALRTSANLSELVPLEEEREFLIIREQDANGQVTLSLRQLELQQAWEELTQMQESGKVLQVRVSGANKGGVTVDVQGMRGFIPRSHLIDRDNIEGLIGQALTVSFLEVDRDREKLVLSQRLATQSSAFSQLQIGQLVEGKVSSIKPFGVFIDMEGISGLLHIKQVSQKYIENLSQVFSSGQILKAMVIDLDESRGRISLSTRILENYPGEMVDKMADVMDTAEERSERARKTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-12-20" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2A5P1F2</accession>
    <name>A0A2A5P1F2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004370</name>
        <name evidence="2" type="ORF">CP500_004375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56648">
        <property type="protein sequence ID" value="PHX56648"/>
        <property type="gene ID" value="CP500_004370"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56662">
        <property type="protein sequence ID" value="PHX56662"/>
        <property type="gene ID" value="CP500_004375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="8112" checksum="B0AFA2F57E1C454E" modified="2017-12-20" version="1">MALTELLPTIRQLSAIEKRELIRILMAEEDISEDIFPLEPYNIYYLPTPYDNFGAGAALMQAMNLANHNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-12-20" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2A5P1T1</accession>
    <name>A0A2A5P1T1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007930</name>
        <name evidence="2" type="ORF">CP500_011990</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55214">
        <property type="protein sequence ID" value="PHX55214"/>
        <property type="gene ID" value="CP500_011990"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55967">
        <property type="protein sequence ID" value="PHX55967"/>
        <property type="gene ID" value="CP500_007930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="20"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="168" mass="19883" checksum="27E7601843E8E96D" modified="2017-12-20" version="1">MGLYRSNPCNHQVRLVSVLWGKTWYYYLTNVKNPQKLSARQVCELYRRRWRVEEAFLLTKRLLGLSYLWVGGNNGVEIQVYATWIFYAVINDLCSSVAVELGQPKERISVEMVFRGLYHFSHYLLRGKMTDAVTYLVEHHKMLGLIKQERKRHRDNAAIEREIWESTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-12-20" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2A5P8M1</accession>
    <name>A0A2A5P8M1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type II toxin-antitoxin system HicA family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017270</name>
        <name evidence="6" type="ORF">CP500_017305</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HicA mRNA interferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54217">
        <property type="protein sequence ID" value="PHX54217"/>
        <property type="gene ID" value="CP500_017270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54223">
        <property type="protein sequence ID" value="PHX54223"/>
        <property type="gene ID" value="CP500_017305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038570">
        <property type="entry name" value="HicA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8359" checksum="1BE09DEA22DC6508" modified="2017-12-20" version="1">MPKMPRISSREAIRALERLGFEQVRQTGSHVVMKKATEEGEIGCVVPVHQELKVGTLSGILKQAQVTVEEFIENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUG2</accession>
    <name>A0A2G4EUG2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartate ammonia-lyase</fullName>
            <ecNumber evidence="3">4.3.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aspA</name>
        <name evidence="3" type="ORF">CP500_022945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000253">
        <property type="protein sequence ID" value="PHX53171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53171">
        <property type="protein sequence ID" value="PHX53171"/>
        <property type="gene ID" value="CP500_022945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008797">
        <property type="term" value="F:aspartate ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="1">
        <location>
            <begin position="19"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="2">
        <location>
            <begin position="413"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="474" mass="50825" checksum="5C1B35EF630FD450" modified="2018-01-31" version="1">MTEQPTATYRTESDSMGDKQIPSNVYYGIQTLRAVENFPISGIKPLSTYVDACVIIKKATAIANGALDCIPQDISQAIVQAADEILAGKLRDQFVVDVYQAGAGTSHHMNVNEVLSNRALEILGDEKGNYKRVSPNDHVNYGQSTNDVIPTAIRIGGLLALEKTLLPALSNAVAALESKATEFQDIVKSGRTHMQDAVPVRLGETFRAWAQILREHTVRIETASGDLTSLGLGGSAVGTGLNTHPEYSQKVAQILSELIDKPLKPAPNLMAAMQSMAPFVNVSGALRNLAQDCVKMSHDLRLMDSGPKTGLKEIQLPPVQPGSSIMPGKYNPVMAEMTSMVCFQVMGYDSAIALCAQAGQLELNVMMPLIAYNLIHSIEILGNTISALTTKCVEKIEAKGDRCLAYAEGSLALVTALNTHIGYLNAAAVAKESLETGKSLRQIVLERGLMSLEDLAKVLDLEKMSAMPTSSANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUK7</accession>
    <name>A0A2G4EUK7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000237">
        <property type="protein sequence ID" value="PHX53223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53223">
        <property type="protein sequence ID" value="PHX53223"/>
        <property type="gene ID" value="CP500_022640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="401" mass="43220" checksum="D8F93FDFC1579CB0" modified="2018-01-31" version="1">MQINQLAFLFIDVILFAIALILLIPVAVLFLECTAALLSGPNQTSETKSPRPKIAVLIPAYNEAAGIAATISTILPQLTPDDRLLVIADNCTDETAEIARKCGASAIERQDTQRKGKGYALDFGLESIASDPPEVVIMVDADCICGPDALETLARVAVASQRPVQATYLMEQPPNPTPKDSISALAFLVKNLVRPSGLKQLGFPSLLTGTGMAFPWSIIRSVSLASGNIVEDMQMSLDLAIAGNPTMFCPEARVTGCLPQQQQAATSQRTRWEHGHIQTLLTQTPRLATASLQQKRFDLLAIALDLSVPPLSLLVAIWLAAFAASLLAATFGTSPIPAIFFAAEGLLILISIVGAWAKFGRADISGSTLLSVPFYILWKIPLYLGFILKRQTKWVRTERDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUQ6</accession>
    <name>A0A2G4EUQ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000225">
        <property type="protein sequence ID" value="PHX53273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53273">
        <property type="protein sequence ID" value="PHX53273"/>
        <property type="gene ID" value="CP500_022375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044048">
        <property type="entry name" value="Big_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19078">
        <property type="entry name" value="Big_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Big_12" evidence="1">
        <location>
            <begin position="192"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="1">
        <location>
            <begin position="288"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="379" mass="38067" checksum="1360DE327C505F59" modified="2018-01-31" version="1">MANRNDNTASILLNTTATGATTPTFATKVDFTTGSAPKSVSIGDFNGDGKPDLAVANQYSNSASILLNGSIPKVTAVTATTPDGSYGVGSTIAIAVTFDAAVTVTGTPQLQLETGTTDKFATYTSGSGGNALTFNYVVQAGDTSADLEYLATTALTLNGGTIKDSLAVDAVLTLPALATANSLGGSKAIVVDAVAPTVALTSNSTPTVNGLFTVTATFSENVTGFDNTDITVANATVGNLVTVDAKTYTFDVTPTASGNVTVDIPAAKATDTAGNNNTAATQLTRTADVTAPTVTLTSASTTTVNGLFAVTATFSEDVTGFDNTDITVANATVGNFVTVDAKTYTFDVTPTADGKVTVDILGAKATDAATITSASFRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUX6</accession>
    <name>A0A2G4EUX6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF928 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53335">
        <property type="protein sequence ID" value="PHX53335"/>
        <property type="gene ID" value="CP500_022035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010328">
        <property type="entry name" value="DUF928"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06051">
        <property type="entry name" value="DUF928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013881973" evidence="2">
        <location>
            <begin position="19"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="245" mass="26712" checksum="15A9B735F2DF8B8D" modified="2018-01-31" version="1">MKRFLHLAKLTVALSAIAATVPTLSAPVQAQSQPILLSQNLNFQPPDVTAPSNRQGGTHRGNGQCPGGLSITPLVPTSNIGLTLTDSPTFFVYVPQTDAPIEFTLLSEKEDELIYETGFKVDKPGIVGVRVPSGNKTKSIEAGKRYVWSFSMICDPQDRSADLVVKGWVQRVEKQANIQSDLQKSDPITRLKVYAQNGIWYETLSALADLRSQTPSDSILTAEWNKLLHSQGLDSIATKPLVQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV02</accession>
    <name>A0A2G4EV02_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021885</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000209">
        <property type="protein sequence ID" value="PHX53364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53364">
        <property type="protein sequence ID" value="PHX53364"/>
        <property type="gene ID" value="CP500_021885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SLBB" evidence="4">
        <location>
            <begin position="381"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="514"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="592" mass="64789" checksum="1A5AB0AB6E0E495B" modified="2018-01-31" version="1">MIGALPSIAQLPVLRPTLPTPNPNRPRVPPPPPPGSNLPIRNSGLPTQESAYILGSGDRIALDIFGVPEFSKEYQVLVDGTLNLPIIRSVSIQGLTLQQAANAITKRYEPFINVPVVTVTLMVARPLNIGIAGEITRPGSYKINPSREGGGVKFPTLMEMLQLAKGVTSAGDMRTVQIRRPRRSGAEQIITVNLQDFLDTGNLRQDVTIRDGDTIFIPTASSLNTQEVRQRASANFSADITKPIGVVIVGEVNRPGPYTISAADLRSTNQQTELGFVSIEQQQGGGAVVGLPTITRALKISGGITTEADIRRVQIRRQIKGGTEQTILVNLWDLLQKGDATQDVLLQEGDSIIIPTAANVDLTEVSQLGSTSFSPNAISINIVGEVVRPGALLVKPSTSLHQALLTAGSFNQLRAKKDKVELLRLNANGTVSRRTIEVDFAQGLNPNNNPTLRNNDVILVARSGYARVGDNINTFLQPIAGVASVINTVSGVLTGVQATMSAFENLFLGGNFERKNQLDQLRQQREDRQQQREDRQLQLDLQRQDRLQQAEDRRLLLQDRQRQIDVENQRLQIQNQQLQLQQQQPQQIQSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV11</accession>
    <name>A0A2G4EV11_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt ECF transporter T component CbiQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cbiQ</name>
        <name evidence="6" type="ORF">CP500_022410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000226">
        <property type="protein sequence ID" value="PHX53270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53270">
        <property type="protein sequence ID" value="PHX53270"/>
        <property type="gene ID" value="CP500_022410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006824">
        <property type="term" value="P:cobalt ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012809">
        <property type="entry name" value="ECF_CbiQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02454">
        <property type="entry name" value="ECF_T_CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="30098" checksum="E5EA5099D8AB7375" modified="2018-01-31" version="1">MNHQIDSLAYTNRLRGLPPTHKLSFAIALLILSLLSGAIVQLSIALWLAVWIVIYAGIPGKLYLRLLSLPLVFLLTSLPALVMGGIQLNQIQAIHSDIWQGWGISIGNFYLYVSRTGLYQVSLLFPRTLASTSCMYFILLTIPFTETLQILRKLRFPPLLTELLLLMYRFIFSLLAIADELWIAQNSRCGYRTWKLGMRSLGILIGQLLQRTLVNYRQVSLSLASRGFNGELRVWHSSPYKPSPRYTFEALFGCTVLSLLSVVFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV36</accession>
    <name>A0A2G4EV36_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53403">
        <property type="protein sequence ID" value="PHX53403"/>
        <property type="gene ID" value="CP500_021660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7392" checksum="CD5393D24D7D6D62" modified="2018-01-31" version="1">MQAKLQEQLSPADAEVILRHLPERIQAALIARAAEIEYPIAATIEMAIASFLDTEALGFVDCKPGRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV57</accession>
    <name>A0A2G4EV57_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000211">
        <property type="protein sequence ID" value="PHX53346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53346">
        <property type="protein sequence ID" value="PHX53346"/>
        <property type="gene ID" value="CP500_022000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="7859" checksum="4379830C6D976D00" modified="2018-01-31" version="1">MFFIQLIPGAISEILASVSDTGTLTIADRYGLMAAILDESLEDEDRNSMNRLLRSVLRGRVKMVNELSAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVB1</accession>
    <name>A0A2G4EVB1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage holin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000191">
        <property type="protein sequence ID" value="PHX53482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53482">
        <property type="protein sequence ID" value="PHX53482"/>
        <property type="gene ID" value="CP500_021250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007165">
        <property type="entry name" value="Phage_holin_4_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37309">
        <property type="entry name" value="PTHR37309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04020">
        <property type="entry name" value="Phage_holin_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="12640" checksum="1F734327C241D055" modified="2018-01-31" version="1">MLSFLLTWVVAAVSLVITAYIVPGITVVSFPAAMLAAVVIGFVNAVVRPILTVLTLPLSILTLGLFLFVVNAISLSLASWLAGAFSIGFAVNGFWPALFGSVVLSFVSGLIGRFVNPDGISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVB7</accession>
    <name>A0A2G4EVB7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000192">
        <property type="protein sequence ID" value="PHX53475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53475">
        <property type="protein sequence ID" value="PHX53475"/>
        <property type="gene ID" value="CP500_021290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037997">
        <property type="entry name" value="Dgk1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303">
        <property type="entry name" value="PTHR31303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="25053" checksum="E5F798C3E8C068FF" modified="2018-01-31" version="1">MSIFAEIPTVWLQISLVGIWLGLILLVAEGLNRFTSVDPEVSRKVVHIGTGNVILLAWWLEIPGWVGITAGILAAAIALISYQVPILPSLNSINRQSWGTFFYAVTISILVAWFWPIQHQEYAALGILVMTWGDGLAAVIGQKYGQHIYRVWGIKKSWEGSATMYLVSFVVSSLILLVVQGNVWQIWAVSAIVALVAASLESVSKWGIDNLTVPIGSAAIAFFLNQFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVQ8</accession>
    <name>A0A2G4EVQ8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxysome shell protein CcmK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Carbon dioxide-concentrating mechanism protein CcmK</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ccmK</name>
        <name evidence="6" type="ORF">CP500_020530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the shell proteins of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered. Assembles into hexamers which make sheets that form the facets of the polyhedral carboxysome. The hexamer central pore probably regulates metabolite flux.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexamer. Interacts with CcmN and CcmO in the carboxysome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 4">Carboxysome</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The tight homohexamer forms a small pore which is positively charged.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the bacterial microcompartments protein family. CcmK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000171">
        <property type="protein sequence ID" value="PHX53623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53623">
        <property type="protein sequence ID" value="PHX53623"/>
        <property type="gene ID" value="CP500_020530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00854">
        <property type="entry name" value="CcmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046380">
        <property type="entry name" value="CcmK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044872">
        <property type="entry name" value="CcmK/CsoS1_BMC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00936">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143414">
        <property type="entry name" value="SSF143414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51930">
        <property type="entry name" value="BMC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="1 4" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="4" id="KW-1282">Carboxysome</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC" evidence="5">
        <location>
            <begin position="4"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11158" checksum="BAEC9D030B07B30C" modified="2018-01-31" version="1">MGVAVGMVEVLGLPSAVEVADSMVKAARVTLVRYEKITRAYWTVIVRGDISEVQAAVAAGIESVKKVDGGKLLSYHIIARPHENLDYILPIGYTPEVEQFRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVV5</accession>
    <name>A0A2G4EVV5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxysome shell vertex protein CcmL</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Carbon dioxide concentrating mechanism protein CcmL</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ccmL</name>
        <name evidence="5" type="ORF">CP500_020265</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 4">Probably forms vertices in the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered. Has been modeled to induce curvature upon insertion into an otherwise flat hexagonal molecular layer of CcmK subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homopentamer. Interacts with full-length CcmM.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Carboxysome</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The tight homopentamer forms a pore with an opening of 4-5 Angstroms in diameter which opens into a wider tunnel at the base of the truncated pyramid. The pore is positively charged.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CcmL/EutN family. CcmL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000165">
        <property type="protein sequence ID" value="PHX53663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53663">
        <property type="protein sequence ID" value="PHX53663"/>
        <property type="gene ID" value="CP500_020265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01614">
        <property type="entry name" value="EutN_CcmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00858">
        <property type="entry name" value="CcmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046387">
        <property type="entry name" value="CcmL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004992">
        <property type="entry name" value="EutN_CcmL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036677">
        <property type="entry name" value="EutN_CcmL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36539">
        <property type="entry name" value="PTHR36539"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03319">
        <property type="entry name" value="EutN_CcmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159133">
        <property type="entry name" value="SSF159133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51932">
        <property type="entry name" value="BMV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="4" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="4" id="KW-1282">Carboxysome</keyword>
    <keyword evidence="1 4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="10892" checksum="55F0F1E62754369B" modified="2018-01-31" version="1">MQMAKVLGTVVSTQKEPSLRGSKFLLLQFINEEGSPVPGYEVAADCVGAGIDEWVLVTRGSAARIAPGSENRPIDALVVGIIDTVNVENRLIYSKKDDGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW24</accession>
    <name>A0A2G4EW24_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53724">
        <property type="protein sequence ID" value="PHX53724"/>
        <property type="gene ID" value="CP500_019870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11952" checksum="7E4296234D51EDFD" modified="2018-01-31" version="1">MLQRKIYQLCCDGREVSIFLRDQQRWIERARILDIEGDLVTLRYETDEEDELSSWEEMVRLESIGSVSQKLASISRTCEPLVSDDCPEAEQIRNHYPDSSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW49</accession>
    <name>A0A2G4EW49_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000155">
        <property type="protein sequence ID" value="PHX53782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53782">
        <property type="protein sequence ID" value="PHX53782"/>
        <property type="gene ID" value="CP500_019605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="5"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="14937" checksum="FDB89683F91E7F63" modified="2018-01-31" version="1">MKLKRLGHVAVCVQDIEKSAEFYRNLGMELVWKDPDWAYLKAGEDGLALLSPSYAQAGPHFGFVFDSRTEMESAYEQLKAEGVSVTHIHEHRDGTASFYGRDPDGNGFEYLYEPAPSPIPGTSLPVAEESEVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWA6</accession>
    <name>A0A2G4EWA6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3148 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53809">
        <property type="protein sequence ID" value="PHX53809"/>
        <property type="gene ID" value="CP500_019530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010258">
        <property type="term" value="P:NADH dehydrogenase complex (plastoquinone) assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021495">
        <property type="entry name" value="CRR42-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36799">
        <property type="entry name" value="PTHR36799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11347">
        <property type="entry name" value="DUF3148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8660" checksum="71F810F46F638CBF" modified="2018-01-31" version="1">MEKEFTVGQKVRVVAMPPYVKTAERMPMLRPANVIAIGAEGIVFDRRPGNYWGIRFEKGAFLLDSQYIEAAEDIVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWL4</accession>
    <name>A0A2G4EWL4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_018825</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000139">
        <property type="protein sequence ID" value="PHX53935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53935">
        <property type="protein sequence ID" value="PHX53935"/>
        <property type="gene ID" value="CP500_018825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033415">
        <property type="entry name" value="CHASE6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019278">
        <property type="entry name" value="DICT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17150">
        <property type="entry name" value="CHASE6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10069">
        <property type="entry name" value="DICT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="442"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="187"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="415"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="662" mass="74598" checksum="2FF4E9E34E2071EF" modified="2018-01-31" version="1">MIVPISVLAELLQTLPQLRAQIYFKSSMTALSHAMEDLVLAGSDEPLVIATFQRERFYRQEAHRYRRIALRSSQVYVLAGPETEFKNSSECHETVAFAPEEPLSQEWNLVVLGHEYSTCLICQEKIVPIENQDSSEPLLMDQARRFEGIWTFDREVSCQAATLLLDRIVKYRPELAEKIDRARTTYKLVKTPKKTRKSTNSTSTKSDKTLGKPPKLPNPKLSDAFAERLVTYLQAGQHKLLKAYGAIAAQERKERLVNLITTAMRQSLNPQEIVEVAVQELGTALSASRCLIYRCKATDIATKIDREFLRQDTDSLLHQTWPLQENPIFRDAVKNQERVYIQDTAQHPRIVNTESLQRSVKQWQIVSWLMVPVLYQGRVLGMVELHQCRSTVAWEEDELALVEAIATQLGAALIQAETYAHLEELNQQLEALDRTRSNLIAITGHELRTPLSTIQVCLESLNTEPDMPAELRKIMLETALGDADRMRKLVQDFLTLSHLESGRVAWNVESLTLQECVDLALSSVRARGYDKKLPQIIAEVSAELPLVQADGEWLVEVLSKLLDNACKFTTPQGIVTIRAKCNGYRMVEVLVSDTGRGIEANSLKVVFDRFYQEEGALRRSTGGTGLGLAICKQIVAGWGGKIWVDSPGKDKGSEFHFTIPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWL8</accession>
    <name>A0A2G4EWL8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000147">
        <property type="protein sequence ID" value="PHX53868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53868">
        <property type="protein sequence ID" value="PHX53868"/>
        <property type="gene ID" value="CP500_019215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="366" mass="41773" checksum="6BDC93EF7290C91E" modified="2018-01-31" version="1">MNISKKNLDLPLISVIIPAYNAEMFIAKTLLSVLSQTYQNIEILVVNDGSTDTTAEIVTSFTQKDSRVILLQQSNTGVAAARNLAIAKARGEYIAPIDADDIWYPQNLEKQLECLIKSEQSVGVVYSWSLDINEKDLLTGGFYNSTIEGEVYKALVYKYFIGNASSSLIRRLCFEKVGGYNCQLKAQSAQGCEDWELHLRIAEHYQFKVVPEFLVGYRQITSSMSCNFAAMAKCHALIMADVRHSHPEIPASIYHWSSSNFYIYLAVKSNRSSNYRSTLFWLYRAFKEDLFMTILRHNSYILSIESILKILVAPITQSALESKQKSESSQRTTIATINRRTSIHKMLPSQVYERMRFNRFANRERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWQ7</accession>
    <name>A0A2G4EWQ7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein CP500_019030</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53908">
        <property type="protein sequence ID" value="PHX53908"/>
        <property type="gene ID" value="CP500_019030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="12487" checksum="4F34C9137F0E28AF" modified="2018-01-31" version="1">MTKSGQGFGFGLGKMKELTEAFKKAQQVQEGAKKLQEDLDQMEIEGIAGGGLVKVFLSGNQEPRRVEISPDALGEGAEVVSELVTVAMQDAYTKSTTMMREKMEELTGGLNIPGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWR2</accession>
    <name>A0A2G4EWR2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">LL-diaminopimelate aminotransferase</fullName>
            <shortName evidence="7">DAP-AT</shortName>
            <shortName evidence="7">DAP-aminotransferase</shortName>
            <shortName evidence="7">LL-DAP-aminotransferase</shortName>
            <ecNumber evidence="4 7">2.6.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dapL</name>
        <name evidence="9" type="ORF">CP500_018730</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2S,6S)-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23988"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="EC" id="2.6.1.83"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (aminotransferase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.83" evidence="4 7"/>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53961">
        <property type="protein sequence ID" value="PHX53961"/>
        <property type="gene ID" value="CP500_018730"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00466"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010285">
        <property type="term" value="F:L,L-diaminopimelate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033362">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01642">
        <property type="entry name" value="DapL_aminotrans_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019942">
        <property type="entry name" value="DapL/ALD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43144">
        <property type="entry name" value="PTHR43144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03542">
        <property type="entry name" value="DAPAT_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="8">
        <location>
            <begin position="36"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="7">
        <location>
            <begin position="108"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="7">
        <location>
            <begin position="247"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="412" mass="45263" checksum="0E6DA167123D5AFD" modified="2018-01-31" version="1">MATINDNYLKLKAGYLFPEIGRRVKAYADANPGAPIIRLGIGDVTEPLPEACRLAMVAAVEEMGSRDTFKGYGPEQGYEWLRERIAEHDFKARGCDIDASEIFISDGSKCDCGNILDIFGNDNAIAVTDPVYPVYVDTNVMAGHTGDANENGEYEGFVYLPITAENNFTAQIPTDKKVDLIYLCFPNNPTGATATKEHLQAWVDYAKANGSIIFFDAAYEAYITDPSLPHSIYEIEGARDCAIEFRSFSKNAGFTGTRCALTVVPKTLTGKAADGSDVEIWKLWNRRQSTKFNGVSYIVQRGAEAVYSEAGKAQIQALVNFYMENAAIIREKLTAAGIEVFGGENAPYVWVKTPNGLSSWDFFQKLLETCNVVGTPGSGFGAAGEGYFRISAFNSRENVEEAMRRIVEKFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWS1</accession>
    <name>A0A2G4EWS1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54002">
        <property type="protein sequence ID" value="PHX54002"/>
        <property type="gene ID" value="CP500_018355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="18"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="212" mass="24666" checksum="F82852D87D72F347" modified="2018-01-31" version="1">MLLTKPRADRVILYNISWQQFENLLIELGESRAARLAYDNGTLEIMTPLLEHEYYKETIGITIQDIAEVLEKDYESLGSTTWKREIKKAGVEPDNCFYFQNEAKIRGKLQLNLEQDPPPDLVLEIDVTSKSINRFPIYARLGVPEIWCYDSGELKIYQLEGAEYIEVQISSIFPTLPIQEIPKLIEKHRYSGRLSLRKAVREWVREKSTVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX21</accession>
    <name>A0A2G4EX21_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tox-PL-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53697">
        <property type="protein sequence ID" value="PHX53697"/>
        <property type="gene ID" value="CP500_020045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028910">
        <property type="entry name" value="Tox-PL-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15643">
        <property type="entry name" value="Tox-PL-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tox-PL-2" evidence="1">
        <location>
            <begin position="18"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="142" mass="16421" checksum="C029AECADE278F7E" modified="2018-01-31" version="1">MGSENSEPPESWTNEDIYREVSKIVSQFRLYQCYEAVQAVVEWLETRDRKGTILRIKTKYDEEDYILSQRLESQGITESITLNGQHYGIEVQGLVFDNLSVTGITREDWLNDFQSISGEFIITEFDSTTFNQNEGQSDESTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX25</accession>
    <name>A0A2G4EX25_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Isopentenyl pyrophosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000125">
        <property type="protein sequence ID" value="PHX54105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54105">
        <property type="protein sequence ID" value="PHX54105"/>
        <property type="gene ID" value="CP500_017955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="49" mass="5913" checksum="0020733FC5A895E1" modified="2018-01-31" version="1" fragment="single">WGDGEMGRFGDSEIRRWGDSEIRRFGDGEIRRWGDWEMGSFHMGWKYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXA2</accession>
    <name>A0A2G4EXA2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54070">
        <property type="protein sequence ID" value="PHX54070"/>
        <property type="gene ID" value="CP500_018050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8578" checksum="3EEA3FF60CD92BE0" modified="2018-01-31" version="1">MPVPQRVNFLVEQARCLFRKGATGKMPVPQRVNFLVEQARCLFRKGATGKMPVPQRVNFLVEQASCLFRKGLLSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXB5</accession>
    <name>A0A2G4EXB5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54116">
        <property type="protein sequence ID" value="PHX54116"/>
        <property type="gene ID" value="CP500_017790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013565847" evidence="1">
        <location>
            <begin position="29"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8034" checksum="EB4D674848CB705A" modified="2018-01-31" version="1">MKPTVLISSTILAAITVLGLGKASQALSTPATVKSTVNNEVSMLFPSNLVVRWCTDTNRAQYPCPRLVMPQDSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXL3</accession>
    <name>A0A2G4EXL3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proton extrusion protein PcxA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pcxA</name>
        <name evidence="10" type="ORF">CP500_018960</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in light-induced Na(+)-dependent proton extrusion. Also seems to be involved in CO(2) transport.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CemA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53897">
        <property type="protein sequence ID" value="PHX53897"/>
        <property type="gene ID" value="CP500_018960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01308">
        <property type="entry name" value="CemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004282">
        <property type="entry name" value="CemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33650">
        <property type="entry name" value="PTHR33650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03040">
        <property type="entry name" value="CemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 8" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="452" mass="51652" checksum="0F71D239DD4DF555" modified="2018-01-31" version="1">MNTSLWNKFVKYLYSARQWYRETPERALEQAYEAALAIKAIEDEHFGGQPIGDRAGDYGYSTLSYFKSDLQQYLKVIQTRMVEFHASRYFLELPQRVAAQPKAGVLGDRYQKGLGINTKDRASLIFEKLEFIDRVLSKYIYGKSTAIVPIDRRKNVPVNSKNGSPQPYQNNSSPNSNQSDADEVDTYIDEVSLLPRSLLGTLNRITKELDPLAEEEVVKNFRNSKIKTVISLRFILLLILVPLLTNQLTKNFIVGPIVDRVRTQNNAALFINIDLEEEAFKELAKFEQHLKFQTLIGKAPSISSEERKKLVEEKAIELAEEYGHESSGAIKNIFADLISCVTFVLVLLSHKKEIEVLKSFMDDVVYGLSDSAKAFVIILFTDVFVGFHSPHGWEIVLEGVSRHFGLPENRQFIFLFIATFPVILDTVFKYWIFRYLNRSSPSAVATYKNMNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXM6</accession>
    <name>A0A2G4EXM6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2854 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54200">
        <property type="protein sequence ID" value="PHX54200"/>
        <property type="gene ID" value="CP500_017465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021275">
        <property type="entry name" value="DUF2854"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35551">
        <property type="entry name" value="PTHR35551"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11016">
        <property type="entry name" value="DUF2854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="20053" checksum="5B2A3AD02804CB66" modified="2018-01-31" version="1">MFRKISLASLALVVGSILAVVGFAAYFTDQPTLNLAGFFYGIPLLLGGLALKAAELEPADFTEPTSPEVLLLREHQATETQNQVRKDVTRFRYGQPAHLDDALERLGLAPTDEERPVLRGLREISVDGAYGLILEFHSPLIAIELWEEKQAKIATFFGPGLHAKVSQVAEDQIELALIKSEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXQ6</accession>
    <name>A0A2G4EXQ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphonate ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54258">
        <property type="protein sequence ID" value="PHX54258"/>
        <property type="gene ID" value="CP500_017150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="331" mass="35586" checksum="6BCBD86855201AE0" modified="2018-01-31" version="1">MNVKLKVLAGASAGLLLLGGLVANTMGLGQKAIAQQTPQGDPLRGLRQRDLRAQAPINRIRIVFANRRDATDLQNKANQVAAILSKAMGMPVEAVIGDETAAVEALRADRADVAFVAGRAALKAEQLAKARMYLAEVRSDYSGGNTYDSVFVVRQDSPLRPKGSSKQTLEQLKGKKMAFTSRTSGSGFIFPVGELVGQGLVSGPDRLESFFGNVTYGDGYGSALQAVLKGQAEVATVSEYALLPPWITAAEGKQLRVLQKVPGVPAHGIVIDDRVPAPMREKLINAFMTMNEPANNQLFRSLYNSQKLVKVDHNSHLATLQQALKRAKLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXS9</accession>
    <name>A0A2G4EXS9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54342">
        <property type="protein sequence ID" value="PHX54342"/>
        <property type="gene ID" value="CP500_016650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="189" mass="20694" checksum="A430B01A92CAE723" modified="2018-01-31" version="1">MNQQVLAVIEKISVLGGEQYGESAWRNPIRKDTGPILQALVMASQPKTVLELGTGYGLSTCYLALGNSETIIHTVEFDSAVAEEAKKHFELAGISHRIKQWVCPSSEAISKIPLEIPVPDFVFIDHAKRPYKDDVSAIIESCGGQQILLVADNVEDRKQELADFLDWFPSIALNLTIISTQCGLLVASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYB5</accession>
    <name>A0A2G4EYB5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_015555</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54535">
        <property type="protein sequence ID" value="PHX54535"/>
        <property type="gene ID" value="CP500_015555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="9">
        <location>
            <begin position="3"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="42069" checksum="4800D7C780D8098B" modified="2018-01-31" version="1">MQIYLDYSATTPTRPEAIDAMQKALTQHWGNPSSLHEWGQRAATALELARMQVAGLINALPESIVFTSGGTEADNLAIIGIARLYSTPQHIIISSVEHSAVSETVRQLEQSGWEVTRLPVDKLGRVHPWDLQQSVRSNTVLISIIYGQSEVGTLQPIEALGQIARDRNILFHTDAVQVAGRLPIDVQKLPVDLLSLSSHKLYGPQGSGALYVRPGVELAPILTGGGQELKLRSGTQAVPIIVGFGVAAELASQEMDGETARLIELRDRLFDRLAQVPSLVATGDRYRRLPHHVSFCIVSPNSGTVQVTGKTLVRQLNLAGIGISSGSACNSGKLTASPILLAMGYSKTMAIGGIRLTLGRETTEADIDWTASAIEQILDRLMPKVALSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYD0</accession>
    <name>A0A2G4EYD0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000118">
        <property type="protein sequence ID" value="PHX54177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54177">
        <property type="protein sequence ID" value="PHX54177"/>
        <property type="gene ID" value="CP500_017550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="543"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="1447"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="1738"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2250"/>
            <end position="2314"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1109"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2267"/>
            <end position="2314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="2561" mass="283561" checksum="029899BAC99D0808" modified="2018-01-31" version="1">MYLQKEKLQHINTIAHEGKVVIIATDADGKIWYSVKQDGFEDSYLNTPADQRTGWEGWQQLELPNEDDDQSVIDQETAELTDANNPSSFVLRSCYKTFDQTAVAPVQLVSASGHVYVFRQSKTNTLLCDRFVLDGMTNKLNRKLEVRFKRSRQKYEASKNMKKGASGLTNIDSLDFRDVNGNFFYEPTTELSLVNNLQSGWFSVVLVPTIENDVYRWHIFAYNSQTKKVELTTLLMSEEGLFDVQDYTTFVESNDSLIPRSVPGIIKRTLDLGTVTVINGLSATKYDIQREKQTDDGMQLLRDSTKVMLAIPTSNGNAAAFSFAVAGDGTLSQISSTPSSKIWRNTIRQMLLPLNTLDNIKAIGTTNPPPQGQITRLERGEDDEVQVVSSTDTNLDSTIQVKISGTQNYNIFQQSITKIDDDSFEISSPSTGLGNWEVIPEEESGLIFNGAITAYEITDTGTIKVTAINHGLNDGESLQIVDTRDYNGVYTVKKIDDNKFALDDIKWQTGTAVNLKMESMKRRGLVFDGVNDYVDCGSGILPDSYTKEAWIKWESGVPYNNIISGYSSHAFYLPNGILSAGHNGNWSYVQDTVSLTANTWIHVALTYDSSTQTMKLYKNGQLIKSATSVPLVSTTDRNILIGAFANPPSSFFKGYIADVRLWKVARTEEQIRNSMYLQLTGKELGLVGYWRLGAVAEEGKERKVIDFSVNGNDGVVYGGAYVSAATLSRNLPGTDIPAIKYENEELFAVSENATYEEEFEFKVNPAVDPNNVDGQDGKIFQIIYKGKNNRSAIDWVNIPANATEFIDIGGGWYKAKCRFSVPDGVSLVRSFGIGNIKGSWTNLEIRKQLICLVSDSITEAKYTDTVNLATLADNHAQLAVALKQIELKEPQEALLLIEKRKLELEIASLSLSDTDKQAAITAKNTEISKQQTIINKLQTEVTQCQTTYEAEKQSPLNYWCKLVCRVNEGWIARIYTQTSELLYADVGANGNPYYSNNYFKFVATTDGYYQIVCQYDNKVLMGNFGGGAALPVLGYPSGFTGDIFEWKPEKFSGDYYLIRHRQSQQVLDRGGSEFGTCVWSQHGGVNQHWKIIPIGGETNNNITNAYSAWNNKKSQLATAQQMLSQLKNELSLLQLASGDQSTKKAALLSRLDVVKAEIVTIQTELNTLNTNFINGVKTTQLPPQAMPQIAKDDKGLITQGAWLGFVNSASRLNAIETCEGNVQLSYFDSQGRMRLTNYDATSDSSNTAFEQWIPDAQRACLNFSNANSVVKLSQQVYLSTDWSIEAWFCYPLPETAQWNTLIRGQNGDSHMIVSRDQKLGIYLTNDSLKQYFYDCGFNMESLSTGWHHLTAVGEGDTTRFYIDGKQVGDIKAKAVKDAEASLNLNPTDAAAKQKVEDIKKANLKVSNDVYAIGNNHLAANKPVDYGVMNFDGSGDYIQTVAKLPTGDEITIEYWFKGTSLQSAVRQQDGSNYIVAGWSNQHIISVDGGTTGISVGANATNGSWHHIAMTWKRNTVNGFVSYLDGVLVTQKNSGSVALTAMNASFFIGCYNGGSEFTNGQMAEVRIWKKARTQAEIQANMNKRLTGKEANLVAYFPLNLVETGKVLDLVSGNSGTVVNATKVTSNLALTPVMQGEQFGKVVEVRIWGVALSNEEVEVNSKTLITGNESGLLAYYPMNEATGTEVRDHTGKGNQGTMTNPVWWACAASIGSQEKAANQVMKFDGVNDHITFPAMNINYSQGFSLEVWVRYNSLKSWSRICDFGNGAGVENILLANKGTTNTLGFHVYRGTTSLGVEVANFLELQKWMHIAVTLEPSGSCKVYKNGQLIQSGTSQLPNSVNRTLNYIGRSNWAADAYFDGQMAEFRLWNRVRTEAEIKADLNQRLTGKESGLAIYLPLDEIKFEGSTKKVFDLVGINHGTITEAAIAQDNSSPLMVIGSSLVSAEYSTISLDPATGKKAALMRRLLAAPAVNGVNLLPDKRIETLELKWIGNAQFAPTLLGYIEGPPPVPSENLTLADDYNGATSVELVMSEDVEFNWTRSQDSGLGATAEMLLGVGGEVSVGILAETGMEAKMGFKGNLDFNYNFQNESSITSSSSLSMTDKLELRGTPEADPKFPHLGNRFIPKNIGYALVVSAMADVFVTRLARSKKMIGYQVQPVDGIPPDINTITFLINPAYTMNGSLDGMTGSSATSDRFFKHVPEMRSQYGSLYPASYYRLQEAYELKRQIEAEDKRRESYFSNFDVRMIDETSLDRNIDSGAAPTTIGVQREEDKPSTEMTEEEKQASQKQEVEQFQQESKDAAAKKSEMAKAKQKEIESKIADQEARVHATESFAGWQKRMESIQVRAGKRNIVNTYVWDADGGLRTEAQSFANTVEHTIGGSFTLNAGLGAAFEYLGGAAIELNAQATVNMTQTMSKTESRSKGFELNIDLSGMENKGVTDYKDNPILPGEKVDRYRFMSFYLEPSTQHFQDFFNYVVDPEWLQSNDEEARALRQAQAGKPNKTWRVLHRVTYVERPALMGFGRDVRQFKVRDENVGIGKVLVDVASLQQKVDQILEWINSQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYR9</accession>
    <name>A0A2G4EYR9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54327">
        <property type="protein sequence ID" value="PHX54327"/>
        <property type="gene ID" value="CP500_016770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="84" mass="9624" checksum="5E9AD90273CA7031" modified="2018-01-31" version="1">MSKIARFKLSKVSKCSLARKTNKLLLKYKFYIFKVFEQISRNQAIAQWGDTHSETLIERVKISLPIAIASRNNLGKFRIEGGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZE4</accession>
    <name>A0A2G4EZE4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative toxin-antitoxin system toxin component, PIN family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54882">
        <property type="protein sequence ID" value="PHX54882"/>
        <property type="gene ID" value="CP500_013685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002850">
        <property type="entry name" value="PIN_toxin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00305">
        <property type="entry name" value="TIGR00305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="2"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="53" mass="6022" checksum="CAD0E37DF3DF0479" modified="2018-01-31" version="1">MCRDEKDNNFLELAVSGNANVIVTGDMDLLVLSPFQAVEIVTTDKFIDRYRLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZH5</accession>
    <name>A0A2G4EZH5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_013570</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54912">
        <property type="protein sequence ID" value="PHX54912"/>
        <property type="gene ID" value="CP500_013570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="9">
        <location>
            <begin position="89"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="521" mass="54913" checksum="1440CC125ED94185" modified="2018-01-31" version="1">MNKMNLGKKKSKTVRRSSLNLPAANSWTKVNTFKKLQRAIGRLSPSWQACIPLAAIIVLVWGYAAVAQTAPAPTTEEQLASLKVGMDTMWVMVAGMLVFFMNAGFAMLETGFCRQKNAVNVLAKNLIVFALSTIAYWAIGFALMFSDGNGLIGTSGGFFLWNVTDNSPATGDAYQGIFDSLNWTGVPLNAKFFFQLVFAGTTATIVSGAVAERIKFLDFLIFSLLLVGIAYPITGHWIWGGGWLAKAGFYDFSGSTAIHSVGGWAALMGAAFLGPRIGKYRNGDTVAMPGHNMSIATLGCLILWLGWFGFNPGSTMAVDPNAIAHIAITTNTAAAFGGVAATITAWLYLGKPDLSMVINGILAGLVGITAGCAWINVPNAAIIGIVGGILVVFAVTFFDNLKIDDPVGATSVHLVCGIWGTLAVGLFADGPTTGIYTAGPKAGLLVGGGFDQLIPQLIGIISVGGMTVLLSTIFWYALKVLLGIRVSPAEEAEGLDIGEHGMEAYSGFVKETDFGSRSKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZJ5</accession>
    <name>A0A2G4EZJ5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phytoene dehydrogenase</fullName>
            <ecNumber evidence="5">1.3.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pds</name>
        <name evidence="7" type="ORF">CP500_013330</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This enzyme converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>15-cis-phytoene + 2 a plastoquinone = 9,9',15-tri-cis-zeta-carotene + 2 a plastoquinol</text>
            <dbReference type="Rhea" id="RHEA:30287"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:48717"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
            <dbReference type="EC" id="1.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <cofactor evidence="5">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Carotenoid biosynthesis; lycopene biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.5" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54934">
        <property type="protein sequence ID" value="PHX54934"/>
        <property type="gene ID" value="CP500_013330"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00803"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016166">
        <property type="term" value="F:phytoene dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014102">
        <property type="entry name" value="Phytoene_desaturase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02731">
        <property type="entry name" value="phytoene_desat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="6">
        <location>
            <begin position="10"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="51515" checksum="EEAF3839EF34C7E1" modified="2018-01-31" version="1">MRVAIAGAGLAGLSCAKYLTDAGHTPIVLESRDVLGGKVAAWKDADGDWYETGLHIFFGAYPNMLQLFKELDIEDRLQWKEHSMIFNQPETPGTYSRFDFPDIPAPLNGLVAILRNNDMLTWAEKISFGIGLIPAILQGQKYVEEMDKYSFSDWLKKQNVPPRVEKEVFIAMSKALNFIDPHEISATILLTALNRFLQEKKGSKMAFLDGSPTERLCQPMVDYITERGGEVRLNAPIGEFLLNDDNTVRGFQIRGVKGADSEILTADIYVSAMPVDPLKLMMPQAWGKMDYFKQLEGLEGVPVINVHLWFDRKLTDIDHLLFSRSPLLSVYADMSNTCREYANPDKSMLELVLAPAKDWIGKSDEDIVAATMVELEKLFPDQIPEPAKVLKYHVVKTPRSVYKATPGRQECRPSQTTPISNFYLTGDYTMQRYLASMEGAVLSGKLTAQAISTPNKMKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZT6</accession>
    <name>A0A2G4EZT6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_012955</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245904">
        <property type="entry name" value="M.Tbo703ORF12955P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55018">
        <property type="protein sequence ID" value="PHX55018"/>
        <property type="gene ID" value="CP500_012955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_Mtase" evidence="4">
        <location>
            <begin position="121"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="455"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="485" mass="54500" checksum="B2BDA23DA9BF64C4" modified="2018-01-31" version="1">MNNITHDIVAKLWNLCNVLKDDGVTYHQYVIELTYLLFLKMAKETSTENQLPDGYRWDDLEGQVELERLEFYKLLLIHLGDRGSTLVKEIFANASSSIKKPTTFSTLVTEINKLDWYSAKQEGLGDVYEGLLEKNANEKKSGAGQYFTPRALIDSMVYVMRPTLEDIIQDPAAGTGGFLIAANRYIGENGDPDSWTEKQKRKHRHNTFYGMEHVQDTHHLALMNLMLHGIEFDPQGAGIRYGDTLSPEGEALPKATLILSNPPFGSKKGGGLPTRKDFNFPTSNKQFCFLQHIYQGLKPGGRAAVVLPDNVLFNGNAGKQIRADLMDKCNLHTILRLPTGIFYAQGVKTNVLFFTRGKKEKGNTQEVWVYDLRANMPQFGKRTQLTRQHFAEFEVAFGDDAFGSSASLAKRVDTGEQGRFRKFTRDSIAELDDNLDISWLNDESEDENGKLTEPAALAQEAMAELEAAMEQLRGILEELGEEVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZX1</accession>
    <name>A0A2G4EZX1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">thiD</name>
        <name evidence="2" type="ORF">CP500_012840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55048">
        <property type="protein sequence ID" value="PHX55048"/>
        <property type="gene ID" value="CP500_012840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045029">
        <property type="entry name" value="HMP/HMP-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PTHR20858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00097">
        <property type="entry name" value="HMP-P_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="1">
        <location>
            <begin position="19"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="274" mass="28429" checksum="BFAEF80958BA5F85" modified="2018-01-31" version="1">MVINQTSKIPVALTVAGSDSGGGAGIQADLRTFAFHCVHGTSALSCVTAQNTLGVTRVDALSAEAVAAQIEAVVGDIGVDAVKTGMLLNREIMAVVASQVESWNLGNLVVDPVMVSRSGDRLIDDGAIAFLQDILIPLAAVVTPNRFEAQILSGLEIDSVNDMRSAAEKIHSLGAKAVLVKGGGMKGDLRGIDVWFDGTRLDVLKTENVNTTNTHGTGCTLSAAIAANLALGKDLFTAVTSAKNYVTTALKYALDIGEGQGPVGHFFPLLEKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F046</accession>
    <name>A0A2G4F046_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="7">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="7">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fabH</name>
        <name evidence="10" type="ORF">CP500_012140</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55129">
        <property type="protein sequence ID" value="PHX55129"/>
        <property type="gene ID" value="CP500_012140"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="9">
        <location>
            <begin position="111"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="8">
        <location>
            <begin position="244"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="7">
        <location>
            <begin position="259"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="333" mass="35494" checksum="6BD5BE6393083215" modified="2018-01-31" version="1">MLQQSGFGIAITGSGSCTPQVSLDNNGLSQIVETSDEWIGTRTGIRSRKLANHAMSLCDLATEAAQNAIAMAEILPTDIDLIILATSSPDDLFGSAGQIQYRLGATRAVAFDLTAACSGFVFGLVTASQFIRTGVYQNVLLIGADILSRWVNWSDRGTCILFGDGAGAVVLQASETDRFLGFEIRSDGTQNSSLNLAYQGESKELIDGVSIGQGGFQPITMNGQEIYRFAVRKVPEVIEKAMFRANISAEKIDWLLLHQANQRILDAVSQRLNIPPEKVISNLANYGNTSAASIPLALDEAVRQGKVKLGDTIAAAGFGAGLSWGAVIFQWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F052</accession>
    <name>A0A2G4F052_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-splicing ligase RtcB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_013945</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54827">
        <property type="protein sequence ID" value="PHX54827"/>
        <property type="gene ID" value="CP500_013945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003586">
        <property type="entry name" value="Hint_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00305">
        <property type="entry name" value="HintC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01445">
        <property type="entry name" value="intein_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INTEIN_C_TER" evidence="4">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="644"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="477"/>
            <end position="481"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="588"/>
            <end position="589"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="588"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="620"/>
            <end position="623"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="627"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="644"/>
            <end position="647"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="714"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="715" mass="80379" checksum="FC66146EB88B502B" modified="2018-01-31" version="1">MPYEKLEISTPKPVLSWANHALGAKETNMAKNVASLPFVFKHVALMPDVHLGKGALVGSVIATKEAIIPAAVGVDIGCFTDDTQIPLVDGKSYAIGELARSKKEFSIYSCTETGRIVAAKATAKLTRNNAELVKVVLDNGEEIKCTPDHQFMLRNGEYREARALTTGTSLMPFYSKIDKDGYTLVQQNYSGRWQKAHWMIARSGLLGDIPSFHNQRTVIHHKNFDAADNRPENLEFMGNNDHSTYHRSLVDRNTHWQSLEFEQKRKQAIADKAQTSDGHRYYAERGSKNILKYMEDNPEHFKESVAGNGERGKQYLINYNQSEKGKAKSKEIANRLYTCETCGEPIKTPIGLHNHRKNQHGYNHKVVDVIPLVEKQDVYCLTVPEYGNFALTAGVFVHNCGMAALKMPFKAHKLEGKLKQIRLDIEAAIPVGFAENKEVERTVSNWQEWREFKELHEGVQHQESKALKQMGSLGGGNHFIEVCVDTEDFVWLMLHSGSRGIGNLLAQHHIDTAKDLAKLAEISLPDRDLAYFVAGTKEFAAYWHDLQWAQDYARFNRDVMMNRFKHIVEKHVAGGKPTKPLLKVNCHHNYAEKEVHFGEDVYVTRKGAVRANVQDYGIIPGSMGAKSFIVKGKGNVESYCSCSHGAGRLMSRTQAKNVFTLDDFVRQTEGVECRKDEQFLDEIPGAYKPIEEVMSQQSDLVEVVATLKQVVCVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0D8</accession>
    <name>A0A2G4F0D8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GDP-L-fucose synthase</fullName>
            <ecNumber evidence="2">1.1.1.271</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fcl</name>
        <name evidence="4" type="ORF">CP500_011960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:18885"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57273"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.271"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.271" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55208">
        <property type="protein sequence ID" value="PHX55208"/>
        <property type="gene ID" value="CP500_011960"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00128">
        <property type="reaction ID" value="UER00191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050577">
        <property type="term" value="F:GDP-L-fucose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05239">
        <property type="entry name" value="GDP_FS_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00956">
        <property type="entry name" value="GDP_fucose_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028614">
        <property type="entry name" value="GDP_fucose/colitose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="15"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="168"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="35018" checksum="40C3EC77571E0960" modified="2018-01-31" version="1">MTSLDLSNKRILVTGGAGFLGRQVIDQLVKAGADGDKIAVTRSRDCDLRVMENCKRAADQQDIIIHLAAHVGGIGLNQLKPAELFYDNLMMGAQLIHAAYEAGVAKFVCVGTICAYPNLTPVPFKEDNLWNGYPEVTNAPYGIAKKALLVQLQSYRQQYGFNGIYLLPVNLYGPEDNFDPKSSHVIPALIRKVYEAQERGDKTLPVWGDGSPTREFLYSTDAARGIVMATQNYNDSEPVNLGTNNEIPIRDLIELLCELMEFKGEIVWETDKPNGQPRRCLDTERAKTAFGFTAQTEFKEGLKNTIEWYRKHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0J1</accession>
    <name>A0A2G4F0J1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="11">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">secA</name>
        <name evidence="15" type="ORF">CP500_011570</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="11">Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell inner membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cellular thylakoid membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11 12">Belongs to the SecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55279">
        <property type="protein sequence ID" value="PHX55279"/>
        <property type="gene ID" value="CP500_011570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="SSF81886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="8 11" id="KW-1278">Translocase</keyword>
    <keyword evidence="9 11 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 11 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="14">
        <location>
            <begin position="1"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="92"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="108"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="500"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX55279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="936" mass="106528" checksum="D9ADCB1FB0391D7B" modified="2018-01-31" version="1">MFKNLLGDPNARKLRKFQPWVADIAILEEEFHALSDDQLRGKTAEFKERLAKTKSLNDEKELLDEILPEAFAVVREAGQRVLGMRHFDVQLLGAIILHKGQIAEMKTGEGKTLVATLPAYLNALNGKGVHIITVNDYLARRDAEWMGQVHRFLGLTVGLIQQGMDQVERKRNYNCDITYATNSEVGFDYLRDNMATIMEDVVQRPFNFCVIDEVDSVLIDEARTPLIISGQVENPSEKYIRASQVAASLRKENDEHYEVDEKARNVLLTDEGFGEAENLLGVKDLYDPADPWAHYIFNAIKAKELFIKDVNYIVRENEVVIVDEFTGRVMPGRRWSDGLHQAIEAKERAEIQPETQTLATITYQNFFLLYPKLSGMTGTAKTEEAEFGKIYNLEVTLIPTNRIPSRQDLSDMVYKAENGKWNAIAQECAEMHSQGRPVLVGTTSIEKSELLARLLRELNIPHNLLNAKPENVERESEIIAQAGRKGAVTIATNMAGRGTDIILGGNSEYMGRLKLREYFMPRIVRPDDEEGFTLAQVPGIGGRPAPQGFAPSLKKVKSWKASPQIFPTQISKDAEQMLKAAVDLAVKEYGERSLSELEADDKIAVASEKAPTNDPVIQKLREAYKLIRSEYDAFTSTEHDEVVKFGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTRFFLSLEDNLLRIFGGERVAGLMKAFGVEEDMPIESGMLTRSLEGAQKKVETYYYDIRKQVFEYDEVMNNQRRAIYAERRRVLEGLDSKEQVIKYAEQTMDDIVGAYINPDLPSEEWELEKLVSKVKEFVYLLADMTPDQLEDLSVEEIKTFLHEQVRNAYDMKEAQVNATRADLMRDAERFFILQQIDTLWREHLQQMDALRESVGLRGYGQKDPLIEYKTEGYELFLDMMTDIRRNVVYSLFQFQPQPAMVSTEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0K5</accession>
    <name>A0A2G4F0K5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55285">
        <property type="protein sequence ID" value="PHX55285"/>
        <property type="gene ID" value="CP500_011605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="124" mass="14556" checksum="604DB9A13DC6E805" modified="2018-01-31" version="1">MLDLYDLLGKIKQRSSLYLGKKSLSHLHVFLDGYTFARRQLGIPVTEQETKFEEFQEWIENRFNQADTQSWSRIILFYSEDEADALKRFFDLFEEFLNSEQFPKIDATNNSEMSDELSVVGVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0U3</accession>
    <name>A0A2G4F0U3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable phosphoketolase</fullName>
            <ecNumber evidence="5">4.1.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_011005</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the XFP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.-" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55394">
        <property type="protein sequence ID" value="PHX55394"/>
        <property type="gene ID" value="CP500_011005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01403">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023962">
        <property type="entry name" value="Phosphoketolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005593">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018969">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019790">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018970">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019789">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_ThDP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273">
        <property type="entry name" value="PTHR31273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03894">
        <property type="entry name" value="XFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09363">
        <property type="entry name" value="XFP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09364">
        <property type="entry name" value="XFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017245">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60002">
        <property type="entry name" value="PHOSPHOKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60003">
        <property type="entry name" value="PHOSPHOKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="XFP_N" evidence="8">
        <location>
            <begin position="14"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="XFP_C" evidence="7">
        <location>
            <begin position="593"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="796"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="825" mass="92306" checksum="70D181DB67F5CE5C" modified="2018-01-31" version="1">MMLETTEIPQLKPLSDSELGKINAYWRAANYLSVGQIYLLDNPLLKEPLKLEHVKPRLLGHWGTTPGLNFIYVHLNRLIKAQDLNAIYIAGPGHGGPGLVANTYLEGTYTEYYSNISEDSEGIQRLFKQFSFPGGIPSHVAPETPGSIHEGGELGYALVHAYGAAFDNPDLIVAAVVGDGEAESGPLAASWHSNKFLNPVRDGAVLPILHLNGYKIANPTVLARIPREELESLMVGYGYKPYWVEGSDPETMHQLMAATMDTVIGEIKAIQEEARTNGCSDRPQWPMIVLKTPKGWTGPKQVDGKKTEGSWRSHQVPLAEMASKPGHVQLLEDWMKSYKPEELFDEHGKLIPELAELAPKGDRRMGANPHANGGLLLRDLKMPKFADYAVDVQKPGTVMAEATRVTGRFLRDVMKLNQDNQNFRIVGPDETASNRLDPVFEVTGREWMGSILPEDDEHLSPDGRVMEILSEHLCQGWLEGYLLTGRHGFFSCYEAFIHIIDSMFNQHAKWLKTTRDIPWRRPIASLNYLLTSHVWRQDHNGFSHQDPGFIDHVINKKAEVVRIYLPPDANTLLSVTDHCLRSRHYVNVIIAGKQPALQYLDMDSAIKHCTAGIGIWEWASNDKGGEPDVVMACAGDVPTLETLAAVDILRRDYPELKVRVVNVVDLMTLQPSSEHPHGLSDKDFDALFTKDKPVIFAFHGYPWLIHRLTYRRTNHSNIHVRGYKEEGTTTTPFDMVVMNDLDRFHLVGDVIDRVSKLGYAAAYGKQALRDKLIEHRLYITEHGDDLPEIRDWKWPHGGAVSSETPKETKDPTVTGDQGVRSGAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0W4</accession>
    <name>A0A2G4F0W4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55393">
        <property type="protein sequence ID" value="PHX55393"/>
        <property type="gene ID" value="CP500_010995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="2">
        <location>
            <begin position="205"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="349" mass="39176" checksum="497CDA9100255403" modified="2018-01-31" version="1">MLKEIEIQNFRCFEQIKISGFERVNLIGGKNNAGKTALLEALFLNISPEASSILVLKDLRKESSLVMKAMPDRAWDNLFYGREQGKSILIIGTSDNDDTDEFTIQQYTNPKTIDPKTIMLITGNKTQNVSGISGSDCLTASSKGLINGSNTIITDAIPTPGELPIIPSFTRISGIELTEAYDQARLNEKDSEVLKAFQIIDPAIESVESFSIGEPTLYLRRKGEKRLPLSLFGDAMNRVAEIILKLVNSEHKILLIDEIENGIHYTNQREFWRMLFRLAVELDTQIFATTHSLEMLQAFADVGLEPNQECSSAYFELARKLKTNQIIGIRRDLETLNYALEHQEGVRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Y7</accession>
    <name>A0A2G4F0Y7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55444">
        <property type="protein sequence ID" value="PHX55444"/>
        <property type="gene ID" value="CP500_010710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="351" mass="39875" checksum="6BCCC9E29A73A8DA" modified="2018-01-31" version="1">MNKETNRDAEAFEHHFLNWMLEAPANALSEDEENFTGPFPSQEWGDTGENSEREYWEWDEPDPYDYQVGVHSNEPAPPLTMGEITTVQDRFQTLLKERLRASIESNPPLFPWETEIQSYDHDYPDDVAPQWVPPLHLWTPQLQNIRWGRLPIPIAQGVFAQLLEPCQNLVMSSLREGSKLVQAVDSLFPGQSQELNELAGLVLRGAVRGELDIENFPNYEAARTDQQMVLSLMAAREILESLTLNCPANQPPVSREWLTALGSLTLEAQYQSRSDTEQPMPSLRVECQFPRGGSLELKGENTEATAQRPNSGHLSVELFDPQPDKTYALEVRFQNFDARPLMFAIRPTLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1B1</accession>
    <name>A0A2G4F1B1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HEPN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55550">
        <property type="protein sequence ID" value="PHX55550"/>
        <property type="gene ID" value="CP500_010210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007842">
        <property type="entry name" value="HEPN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05168">
        <property type="entry name" value="HEPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN" evidence="1">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="14290" checksum="CA7BCD165157C2F8" modified="2018-01-31" version="1">MKPEQLELIQKSRESISAARLLLDNGFPGYAAARAYYAMFYIAEAFLDGERMSFSKHSAVIGAFGREFARTGRVPAEFHRFLIDAQDLRNSGDYGGIDTVTVEQAAEQINCAEEFLKLAQNLIGTLPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1F3</accession>
    <name>A0A2G4F1F3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55576">
        <property type="protein sequence ID" value="PHX55576"/>
        <property type="gene ID" value="CP500_010120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="18965" checksum="15AB91B19F2F5027" modified="2018-01-31" version="1">MNDQQEKTKLWKVYGILMGVMVGGAVLILGGQAAWNAVQQNMSKASIENKPQSTSSLPLSTPPVPPEVRSQTNSSTPSDSTERVSFNKGSTGATIRDSVTANQRKRYLLNCGSGQRMTVQVRQGSINVTIISPNNQTIGNAVNGVSQWQGKLPNTGDYIVEISAPNQSGYVINIEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Q8</accession>
    <name>A0A2G4F1Q8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55694">
        <property type="protein sequence ID" value="PHX55694"/>
        <property type="gene ID" value="CP500_009360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12806" checksum="70A74118504BAA6B" modified="2018-01-31" version="1">MANVDLYRQHIQNLLSQHASLVWDERIQAQTIFDTDRDHYQLVYVGWRNQRRIYGPVLHVDIIDNKIWIQQDGTEVGIANELVELGVPKQDIILGFDPPMIRHLSEFAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F212</accession>
    <name>A0A2G4F212_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55782">
        <property type="protein sequence ID" value="PHX55782"/>
        <property type="gene ID" value="CP500_008825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039672">
        <property type="entry name" value="MFS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001927">
        <property type="entry name" value="Na/Gal_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328">
        <property type="entry name" value="PTHR11328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00792">
        <property type="entry name" value="gph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="429"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="474" mass="52496" checksum="87874D9616EAB209" modified="2018-01-31" version="1">MSNTSPPIAATNNPESKKLSFSTKLAYGAGDLGPAITANVLVFFLLLFFTSVAGLSPGTASNILLIGKVWDAINDPIVGVLSDRTSHPWGRRYPWMVYGAIPFGIFFFLQWIVPSENPTILFWYYVIISILFNTAYTAVNLPYTALTPELTQDYNERTSLNSFRFAFSIGGSILSLILAQIIFALVKDNTQKYIILGAVCTVISVLPLYWCFLGTRKHVFSQLQENPVEDNSTSLPLKEQLRIAFNNRPFLYVIGIYLCSWLGVQLTASILPYFVIDWMKLPPAAFTQTAIAVQGTALAMLFVWSQVSQKYGKKAVYFMGMSLWIIAQAGLFFLQPGQVVLMYVLAVMAGVGVSTAYLVPWSMIPDVIELDELQTGERREGVFYSFMVLLQKIGLALGLWLVGQALERAGFLATVQGQAPPVQPDSALFAIRFAIGPLPTIALIAGMILTYFYPITREVHAEILLKLREKKAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F244</accession>
    <name>A0A2G4F244_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_008745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55831">
        <property type="protein sequence ID" value="PHX55831"/>
        <property type="gene ID" value="CP500_008745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="11608" checksum="1A4EA542FC38FDC6" modified="2018-01-31" version="1">MSPVVKIIQPSGILDGTKASQFRLEISDLVEAGADVVLIDFQDVTFMDSSGLGALVLALKTVRAAGSQLFVCSINEQIRILFELTSMDRVFEIFPTREAFNSKILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2A2</accession>
    <name>A0A2G4F2A2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55872">
        <property type="protein sequence ID" value="PHX55872"/>
        <property type="gene ID" value="CP500_008610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="163" mass="18893" checksum="ADA229E17BD49C8C" modified="2018-01-31" version="1">MPTFTKKSTRHFNPEQDTYPCPVCRTGEISPMPMMEALACNFCQHIFTGNEERQMLKMADRQPPVNWHWNGKQWIGAHLEGIEFGWPYFAAAIGLIFLPTTLLGLSAYYFPPIPGSRLSWLPAAWTGLAFLSHLGIVLWLVGEFYQFPLITYFRAWGRRIYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2D2</accession>
    <name>A0A2G4F2D2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55902">
        <property type="protein sequence ID" value="PHX55902"/>
        <property type="gene ID" value="CP500_008380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="205" mass="23411" checksum="8AC1C7D72108183C" modified="2018-01-31" version="1">MVQTAVKLTFEDFLEQYPDGYGIYELVNGEIVEVDATRAHKNVARYLVKCFDGENERLGLDYIVDKDIRVRTVTAAGQEQGRNPDVGVVSASLWNSNVLAYGALREPIQLAVEVVSTNWEDDYVDKFDEYQRLGIFEYWIVDYLAIASRYYLGNPKVPTVFVYRLVEGSYQVQGFRGCDRIISPTFPELDVTVDRVIKSSKIQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2E7</accession>
    <name>A0A2G4F2E7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">T2SSE_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55915">
        <property type="protein sequence ID" value="PHX55915"/>
        <property type="gene ID" value="CP500_008035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SSE_N" evidence="1">
        <location>
            <begin position="12"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="352" mass="39592" checksum="2FDEF5E9116A6889" modified="2018-01-31" version="1">MDSDRIFPLIDTVVPFEACLYYEVLPLSLEGNILKLGIVDPQDDSALDYVQRILAYMNCSVKTEAISSETQHSMLSAYLLHGSQPRETVPTATVADSTQANPTFGDKKTVSSQPKAETIVFEAESEPLTSFCLKPSPATIKPAYSEVSHLPTALQILEVKPLHLSSPVEVLANLPAPQLLQELLGRILLEGIGRLFFERQQLQGQILWSQDGVLKSMLEDIQPLLFQEVIDELKRLTDMPLTRVQHTQEVEVERIYQETHLLLRLRVMPVGGGEEATLQVLRGAALRFYEQQQLSTLSRDALQLAQELQRKVNKIRDRTRLASLPLEGLPALEQVIRNVDYQIEALMNQHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2F3</accession>
    <name>A0A2G4F2F3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sugar kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55941">
        <property type="protein sequence ID" value="PHX55941"/>
        <property type="gene ID" value="CP500_008190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="6"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="285" mass="30244" checksum="184A248856207B02" modified="2018-01-31" version="1">MKTGLFLGLATWDLIYLAEKPPGENQKVVASDCTIAAGGPAANAAVTFGYLGNAAIWAGVLGNHAIAQLIKTDLAEYNVRIVDLSPGRSDPPPVSSIIVTQGTGGRSVISINATKSQVDNQTINPDILTSVNIILIDGHQIPASTEIAQLAKSKNIPIVLDGGSWKPGLEEILPFVGWAVCSDNFHPPNCDNSEQVFAYLSAAGIPNIAITRGEKPILYLSNGKYGSLEIPQIQATDTLGAGDIFHGAFCHYILQNNFIDTLTAAAKIASHSCKFFGTRNWMNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2J8</accession>
    <name>A0A2G4F2J8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AI-2E family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_007920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55965">
        <property type="protein sequence ID" value="PHX55965"/>
        <property type="gene ID" value="CP500_007920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="353" mass="39063" checksum="4D50AE42DBC1F387" modified="2018-01-31" version="1">MRPLTKLPQWWTYGLLFPLAILNCWLALLVFEYFRALITVLVIATVLSFLLDYPVRFLCKYGMKRDRAVLSVLFVTLFVLVVLGVTLAPILLNQLTEFATRLPTWIVSGTEQMEAFHKWAENRNLRIDVRGLTTQLSDRLSAQLQSLTGEILKFGLGAADSILNFLLTIVLTFYLLLHGDKVWEGLFKWFPPKLSVQLRELLPRSFHNYFVGQATLAGLMGLSMTVAFLVLRVPFGLLFGLGVGVMTLIPFGAPFSIWIVSLLITLNNFWLGVTVLAVATVIDQVIENAVAPRLIGSFIGLNPVWILVSLLVGIKVGGVAGLLVAVPMAGFIKNAVDTLQTSRNQSSENVGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2L6</accession>
    <name>A0A2G4F2L6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55985">
        <property type="protein sequence ID" value="PHX55985"/>
        <property type="gene ID" value="CP500_007800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="Pentatricopeptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="2">
        <location>
            <begin position="118"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="473" mass="54578" checksum="AEBC0846DD774794" modified="2018-01-31" version="1">MYIRKIEIKNFRGNDFSWILNTDVNVLIGKNGSGKSTILRMLNEAVLPEDRRLDFRLFDPIDKMIIELENDLVIVVDSASRSITGNQGDTSYDLNTNFINTFDVVENNSAPNTTLLDYQLNKLKQEFIIYQRDLLNKVEEILISDDDSESKDNKLEKIEAVYKTKKIFVKILSELFSQTGKKFDEKAFQFLGTGIENPILPENLSSGEKQILIILLTTLLQDGKPYILLMDEPEISLHIDWQRSLIQNIRQINPSCQIIMVTHSPTTFYGGWIENVTRIEEIQSHSNLVVASEILAEKTEQSKERVQNIEDEFNDFSGNKLAQLYQFNRKINTYTSFTKNECISLLDFLKNREIYPDVITFTTLISKLNNYEDAKEIFDLMELETHSRLSHVKPNDITLNTLIKKVSRAQEGIDLIQSLSDNEKLQLYPDIITFSTLLGKAKNADEIKLLEEVRNYYGVKANDIYLNKLNSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2N9</accession>
    <name>A0A2G4F2N9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nitrate ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ntrB</name>
        <name evidence="8" type="ORF">CP500_007565</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56005">
        <property type="protein sequence ID" value="PHX56005"/>
        <property type="gene ID" value="CP500_007565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005889">
        <property type="entry name" value="NtrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01183">
        <property type="entry name" value="ntrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="87"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="281" mass="30703" checksum="A52E8B0ED06AC430" modified="2018-01-31" version="1">MFIQLNLSAIAIAGVAAWKRAKPAIIRDAVLLPAAGFLGILILWWIIASFKSDLIPTPYQALIANLDYILHPFYQRGPGDLGIGWLLIASLRRVLLGFLLGAIVAIPVGFLIGMSKPAMMALNPLIQIFKPVSPLAWLPIALSIFNLADPSAIFVIFITSLWPTMINTALGVSSVSKDYLDVARVLEMSQWRRITKIILPASLPYIFTGLRISLGIAWLVIVAVEMLTGGVGIGFFVWDEWSRLNLSSVFLAVFVIGITGLVLDWGVGKIQELVTHRSVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2P0</accession>
    <name>A0A2G4F2P0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56031">
        <property type="protein sequence ID" value="PHX56031"/>
        <property type="gene ID" value="CP500_007715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="15"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="188" mass="21296" checksum="68E96434B82110BA" modified="2018-01-31" version="1">MSQTISDKLRFTTADLELLPDNGDRYEIIDGELFMTRAPHWGHQQTCGRFFSVLDTWSMSTGLGRAAINPGLIFTDADNVIPDVVWASNERLAILLDEAGHLTAAPELIVEVLSPGADNQRRDRDLKLRLYSVRGVQEYWIVNWRLRQIEVYRREQTSLRLVATLFSNDELTSPLLPGFSCSVAQIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2R4</accession>
    <name>A0A2G4F2R4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Elongation factor 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_007685</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56025">
        <property type="protein sequence ID" value="PHX56025"/>
        <property type="gene ID" value="CP500_007685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03138">
        <property type="entry name" value="GUFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027518">
        <property type="entry name" value="GUFP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="7"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="604" mass="67076" checksum="CDF933392F2FB97C" modified="2018-01-31" version="1">MTNVPVSRIRNFSIIAHIDHGKSTLADRLLQATGTVQAREMKEQFLDSMDLERERGITIKLQAARMNYTAKDGQEYVLNLIDTPGHVDFSYEVSRSLAACEGALLVVDASQGVEAQTLANVYLALANDLEIITVLNKIDLPGAEPERVKGEIEEIVGLDCSGAILASAKEGIGIDDILEAIVEKVPPPQDTIDKPLRALIFDSYYDAYRGVIVYFRVMDGSVKKGDRVLLMVSGKEYVIDELGILSPTQIPVDELHAGEVGYLGAAIKAVADARVGDTITLVKKPAPEPWPGYTEAKPMVFCGLFPIDADQFPDLREALEKLELNDAALSYEPETSSAMGFGFRCGFLGLLHMEIVQERLEREYNLDLIVTAPSVVYQVTTIKGEVLTIDNPSHLPDPQYRDKIEEPYVQVEMLSPETYVGTLMELSQSRRGIFKDMKYLSQGRTTLIYELPLAEVVTDFFDQMKSRSRGYASMEYHLIGYRENPLVKLDILINGDPVDALAMIVHRDKAYNVGRGLTEKLKELIPRHQFKVPIQATIGAKVIASEHIPALRKDVLAKCYGGDISRKKKLLQKQAKGKKRMKSVGTVDVPQEAFMAVLKLDRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2S7</accession>
    <name>A0A2G4F2S7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome f</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">petA</name>
        <name evidence="15" type="ORF">CP500_007395</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="12 13">Binds 1 heme group covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cellular thylakoid membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome f family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56048">
        <property type="protein sequence ID" value="PHX56048"/>
        <property type="gene ID" value="CP500_007395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031361">
        <property type="term" value="C:integral component of thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.830">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00610">
        <property type="entry name" value="Cytb6_f_cytF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024058">
        <property type="entry name" value="Cyt-f_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002325">
        <property type="entry name" value="Cyt_f"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024094">
        <property type="entry name" value="Cyt_f_lg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036826">
        <property type="entry name" value="Cyt_f_lg_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01333">
        <property type="entry name" value="Apocytochr_F_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16639">
        <property type="entry name" value="Apocytochr_F_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00610">
        <property type="entry name" value="CYTOCHROMEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103431">
        <property type="entry name" value="SSF103431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49441">
        <property type="entry name" value="SSF49441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51010">
        <property type="entry name" value="CYTF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12 13" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Apocytochr_F_N" evidence="14">
        <location>
            <begin position="45"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12 13">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="12 13">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="12 13">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12 13">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602325-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX56048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="329" mass="35333" checksum="10DDEF9B4D6D89A2" modified="2018-01-31" version="1">MPQTNLFAIFRRSVQTIAKTAIIAIVATAFFLSSDIALPQAALAYPFWAQETAPATPREATGKIVCANCHLGAKPTEIEVPQSVLPDTVFEAIVKIPYDTSVQQVVGDGSKGGLNVGAVLMLPEGFKIAPEDRIPEEMKEKVGDLYFQPYSETQENIILVGPLPGEEYKELVFPVLSPNPATDKSVHFGKYLIYVGGNRGRGQVYPTGDKSNNTVYNASVAGTISKISTPEDGGYELTIQPTEGAAVVETIPAGPELIVTEGQTVADGELLTNNPNVGGFGQKDVEIVLQSSTRIQGMMAFLALTMLAQIMLVLKKKQVEKVQAAEMNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2V5</accession>
    <name>A0A2G4F2V5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56086">
        <property type="protein sequence ID" value="PHX56086"/>
        <property type="gene ID" value="CP500_007205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="19"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="261" mass="30595" checksum="8738C3CD5490E295" modified="2018-01-31" version="1">MTAVQELAPSQDIQQNVIFPPGDLYSDEPPMETELHLRQMILLLQCLEWLWKDRNDFYAAGNMTIYYSPRQLKSELCRGPDFFVVLDTERKARKSWAVWEEDGKYPNVIVEILSPNTASIDKGFKKLLYQNTFRTHDYFWFNPYNLELTGFHLVDGEYQPLEPNSQGLLFSQQLDLCLGIYEKKLRLFTTQGELLPTPEEVAQRETQRAEEETQRAEQETQRAQRETQRAEQETQRAAQETQRADRLAAKLRELNIDPDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2W4</accession>
    <name>A0A2G4F2W4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mg-protoporphyrin IX chelatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_007355</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in chlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mg-chelatase subunits D/I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56114">
        <property type="protein sequence ID" value="PHX56114"/>
        <property type="gene ID" value="CP500_007355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01451">
        <property type="entry name" value="vWA_Magnesium_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041702">
        <property type="entry name" value="BchD/ChlD_VWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="7">
        <location>
            <begin position="592"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="388"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="512"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="394"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="415"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="788" mass="85141" checksum="931770CB68C49F14" modified="2018-01-31" version="1">MSALYATPTVTAFPLTAVVGQEAIKLALLLAAVDPGLGGVAIAGRRGTAKSVMARALHSLLPPIEVVKGSFCNAEPEELLVEQASCLLPENNLEQPLAENSQQDTLAENNGQDAFAENNGQDAFAENNGQDALAENNGQDALAENNGQDARTTNTNLATEIIPTPFLQIPLGVTEDRLLGSVDVEQSVKFGKTVFQPGLLAQANRGVLYVDEINLLDDNISNQLLTVLTEGRNQIEREGISFQHPCKPLFIATYNPEEGQLREHLLDRIAIALSADAVLELEQRVQAVDQALSYSNSPQQFLSQYAEDTDNLKTQIILAREWLKDVTIKHEQISYLVEEAIRGAVQGHRAEIFAVRVAKACAAIEGRTEVNAEDLRRAVELVIVPRATVIQSPPDENTPPPPPPPPPQTNSEREQEEEQEPEDEEKDENEDKENEPPEEQDENSIPEEFIFDPEGVILDPSVLFFTQNTSRQGKSGSRSIIFSEDRGRYVKPVLPKGPVRRIAVDATLRAAAPYQKARRERSSNPPPSRAGTGAPPLQLGGQEASQPPLNKGGQEASQPPLNKGGQGGVQRRVFVEQGDIRAKKLARKAGALVIFVVDASGSMALNRMQSAKGAVMQLLTEAYQSRDQVALIPFRGEQAEVLLPPTRSIALARKRLERLPCGGGSPLAHGLTQAVRVGVNARQSGDIGQVAIVAITDGRGNIPLARSLGEPMVDGEKPNIKAELLEIAAKIRGLGMQLLVIDTESKFISTGFAKELAKTSGGKYYHLPKATDQSIAAMTKNALRDAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Y8</accession>
    <name>A0A2G4F2Y8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfiredoxin</fullName>
            <ecNumber evidence="3">1.8.98.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_008720</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-dithiol + ATP + S-hydroxy-S-oxy-L-cysteinyl-[peroxiredoxin] = [protein]-disulfide + ADP + phosphate + S-hydroxy-L-cysteinyl-[peroxiredoxin]</text>
            <dbReference type="Rhea" id="RHEA:17545"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="Rhea" id="RHEA-COMP:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:61973"/>
            <dbReference type="ChEBI" id="CHEBI:61974"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="1.8.98.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfiredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.98.2" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55827">
        <property type="protein sequence ID" value="PHX55827"/>
        <property type="gene ID" value="CP500_008720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032542">
        <property type="term" value="F:sulfiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016692">
        <property type="entry name" value="Sulfiredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21348">
        <property type="entry name" value="PTHR21348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017267">
        <property type="entry name" value="Sulfiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="9">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="9926" checksum="2794B48401A5608E" modified="2018-01-31" version="1">MRIEEIALSQIRRPLPRVNDQTKVSALMESIREVGLNEPIDVLEVEGQYYGFSGCHRYEACQRLGLETIRCKVRRAPRSVLQMHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Y9</accession>
    <name>A0A2G4F2Y9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_007365</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56116">
        <property type="protein sequence ID" value="PHX56116"/>
        <property type="gene ID" value="CP500_007365"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="345"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="172"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="281"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX56116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="462" mass="49839" checksum="3514CC792F506BAE" modified="2018-01-31" version="1">MRVCVIGTGYVGLVTGTCLAHIGHHVICVDNNEEKVKLMKSGQSPIFEPGLSELMSSASASGNLEFTSDLAAGVAHGEILFIAVGTPPLPTGESDTRYVEAVARGIGAHLDGDYKVLVNKSTVPIGSGDWVRRIVLDGLAERQKPQSSEGATGEEVVAKTRVQFDVVSNPEFLREGCAVHDTFNPDRIVLGSNSQRAMDMMIQLYKPIVDREFAENASLPPVPVVTTDISSAEMIKYAANAFLATKISFINEVANICDRVGADVTQVAKGIGLDSRIGSKFLQAGIGWGGSCFPKDVSALVHTADDYGYEAHLMKAAVEVNERQRLIAIEKLQQVLKILKGKTVGLLGLTFKPDTDDLRDAPSLNLIENLNRLGAKVKAYDPIVSQTGMRHGLSGVLVETDPERLADGCDALVLVTDWEQFRNLDYGKMAKLMNHPVMIDGRNFLDKKGLEAAGFQYVGIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F309</accession>
    <name>A0A2G4F309_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipopolysaccharide biosynthesis protein RfbH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56139">
        <property type="protein sequence ID" value="PHX56139"/>
        <property type="gene ID" value="CP500_007065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="392" mass="43992" checksum="E489AC75A6442E1B" modified="2018-01-31" version="1">MWKICQLWSGLSIGRYAAEFEQRFAEWMGVKHCLLVNSGSSANLLALSALTSPKLGDKRLQPGDEVITVAAGFPTTVNPIFQNQLVPVFLDVKLPTYDIDTDQLEAAFSPRTRAIMVAHTLGNPFNLEAVMAFAQKHDLWVIEDNCDAVGSLYQGKKTGTFGHLSTASFYPAHHMTMGEGGAVLTNDTRLKKIVESFRDWGRDCWCPPGVDNTCGKRYGWQLGDLPSGYDHKYTYSHVGYNLKMTDMQAAVGCAQLDKLPEFVAKRRHNFEFLHQQLQDLQDVLVLPEAAPNSEPSWFGFLLSVRENAPFTRNALVQYLEEKRIGTRLLFGGNLVRQPLYQGLQYRVVGKLANTDMVMYSAFWLGVFPGLTEEMLSYVVSTIREFCGEHRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F378</accession>
    <name>A0A2G4F378_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flagellar biosynthesis protein FlgM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56206">
        <property type="protein sequence ID" value="PHX56206"/>
        <property type="gene ID" value="CP500_006770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007395">
        <property type="entry name" value="Zn_peptidase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36434">
        <property type="entry name" value="PTHR36434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04298">
        <property type="entry name" value="Zn_peptidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="225" mass="24414" checksum="10F98C19EA3066ED" modified="2018-01-31" version="1">MFFHPSYLLLIPGMILMFWAQNRVQSTYHKYSQVRSTMGMTGAQVAQEILNRMGVHNVQIEQVAGQLTDHYDPSAKKVRLSEGVYGSDSLAAAAVAAHECGHVLQDVQGYKAMNLRSSLVPAANLGSNIGPMLVVVGVVLGSAGGIFINIGIALFLAVILFHIVTLPVEFDASNRALKLINEFGILQGEENRAAKKVLDAAALTYVATALYSVLQLVQLLMMRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3A3</accession>
    <name>A0A2G4F3A3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56228">
        <property type="protein sequence ID" value="PHX56228"/>
        <property type="gene ID" value="CP500_006600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="10921" checksum="0A1F5F3C302A5BEE" modified="2018-01-31" version="1">MSTVVDIGTLIVRSPEICGNSPRIAGTRVTVGRIATLWKQGITPEEMLENWGYLSLAQIYAALAYYHANKNEIEAILAAELADYDRLEAEYSSEDQASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3N2</accession>
    <name>A0A2G4F3N2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56331">
        <property type="protein sequence ID" value="PHX56331"/>
        <property type="gene ID" value="CP500_005975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019994">
        <property type="entry name" value="CHP03492"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39517">
        <property type="entry name" value="PTHR39517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03492">
        <property type="entry name" value="TIGR03492"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="458" mass="50619" checksum="769A937CAB8CFEBF" modified="2018-01-31" version="1">MRDLGLKILCLSNGHGEDAIALRILRELQQQPHPPELAVLPLVGEGQAFAQLENAPVIGLVQRMPSGGFIYMDSRELWRDVKGGLLQLTIAQFKAIRAWVRSHNDSANQNAVILAVGDIVPLLFAWLSGAPYVFVGTAKSDYYLRDENGPLASQSRGISLEAWSGSVYLPWERWLMTRKRCRAVFPRDALTAETLEKLGIRAYNLGNPMMDELEPENPAPAFYGDDAGFGKRSRSLVITLLPGSRAPEAYANWHLILEAVAGILSTFGDRQLLFLGAISPELNLEALRSILEFFGWNQDGETISQHREGSILRPPISHAQEIQQDSPNFRLPLTFVQRKTTMILSQHNFNDYLYEADLAVAMAGTATEQFVGLGKPAIAIPGAGPQFNPAFAEAQSRLLGPSLILVKHPAEVASAIQLLFRDSNRLELIEENGQRRMGEPGAARRIANCLIERFADSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3P7</accession>
    <name>A0A2G4F3P7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1822 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56390">
        <property type="protein sequence ID" value="PHX56390"/>
        <property type="gene ID" value="CP500_005605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014951">
        <property type="entry name" value="DUF1822"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08852">
        <property type="entry name" value="DUF1822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="365" mass="41845" checksum="1DEEE9B7A9ECDDAE" modified="2018-01-31" version="1">MTGVILFGKFNLFFYRAADMNRKELEELAEKNWHLEDLYKALGQAKQNYKQIEKAQSITPNDKDNLHGILARKKSSEIAIIYNKSYGQTKNELSDRLYKYLRNLLKYEQSVDIELIDIPNQLAERGFKRDSSQGRRETEKVWWRITIELDNPDNFQLQAIVNRLGSVIEKPLIVQKIESGSTLLAFESDRSEYDRIEELYRSGRLDELLKVSVSDLRQITQDSVLIYVRQMYENLFGEGYQPVALILTRSQRNRSRSPNPEKLESVERAKRINLGANQSVNLTVELTPQDEEIDTKIWIEPSGDAVYLPVGLQITVLDELGNPIPQLHKQTGSTDNAVLVTFSLEPGEGFSLKLLLGDASVTETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3S9</accession>
    <name>A0A2G4F3S9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56406">
        <property type="protein sequence ID" value="PHX56406"/>
        <property type="gene ID" value="CP500_005700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="393" mass="42447" checksum="AE646B4B9DD17E3B" modified="2018-01-31" version="1">MSKLKFSALISAVCMMSIVFYGWVGFSQSPQPTVRLTTEPQISQILPFEAESTTPLPPVSLKLQALDAAGIPLENARIKLTILTPPKNPWFTTDFPIVEGTKLLEIEAIAPKGELQIQQMLPIRGNYQLLANVTPIAQNAFTPIQQTLTLSVPENVVKYRNFGILAAILLVVGLSGGLVIGGKQQIQTGEIAPQKVRLLLSGGIIIAIATLLYVNVSAEIAQSEMSMPMSHMMESKPTEKTKPIMQSQGLQVRLSGDVSATVGKTANLQVQVTDTKTNQPVTDVLLNIKVTPAEDEWIAFAYKGAPDAAGKLLWQEQFFDGAPHKVEVEVSPQPNAARQFPPLQVSQTIEVEGVAPPLSVRLTVLAYLTGIVVAGMAIGFGLQRLLLGRSRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F406</accession>
    <name>A0A2G4F406_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_005230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56492">
        <property type="protein sequence ID" value="PHX56492"/>
        <property type="gene ID" value="CP500_005230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="14998" checksum="398268B8CBFD3BCD" modified="2018-01-31" version="1">MTRAIMETDKGTINLELFDADAPNTVKNFVDLAEKGFYDGLAFHRVINNFMVQGGCPQGTGTGGPGYKINCEINSNKHLAGTLSMAHAGKDTGGSQFFICHSPQSHLDGVHTTFGKTEDMSVVNAIRKGDKILSLKIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F426</accession>
    <name>A0A2G4F426_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GGDEF domain-containing response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_006405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56237">
        <property type="protein sequence ID" value="PHX56237"/>
        <property type="gene ID" value="CP500_006405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="179"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="321"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="573" mass="64515" checksum="AFE20581BFFBA7A8" modified="2018-01-31" version="1">MNVPSVLVIDDEPDNFDVIETLLNDRDYQLHYAASGQEAINSLNLFEPDVILLDVMMPGMDGIEVCQRIKAMPKWEALPIVMVTALTTKTELARCLTAGADDFISKPVNRLELTARVRSMLRIYGQYQQLVTFNARLEATVQQRTAELQTMIFQDALTMLPSRTFLLQKLAEILQAGESSFAVVYLDCDRFKLVNGSFGYAIGNQLLIAITERLQHHLRPGDVLARLGEDEFCFLLHQVDDAIALEPFIQAILRGFDTSFVVADFELFMTACIGIALGSSVYQQPEEPLQDADTAMYKAKLRGKGCYQIFDRQMSLAMLNRLTLENDLQRALEHQEFVTYYQPIVNLQTQKVVGFEALVRWQHPDRHMVLPGEFIPCMEETGLIVPVGMLVLKQACQQLRAWHQLGWTQLTMSVNLSVRQFTCPTLLADIDRVLAETAVNPAYLKLEITESAIVDNAQKAIALTEQLRSRQIQISIDDFGTGYSSLGQLHCFPVDNLKIDRSFVNQIQAGNRNYQVVNTIITLSNQLELAVIAEGIETTQQLQCLQQLGCEFGQGYLFSKPLAGAEIEKIYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F438</accession>
    <name>A0A2G4F438_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7 8">2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase</fullName>
            <shortName evidence="7">MECDP-synthase</shortName>
            <shortName evidence="7">MECPP-synthase</shortName>
            <shortName evidence="7">MECPS</shortName>
            <ecNumber evidence="3 7 8">4.6.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ispF</name>
        <name evidence="10" type="ORF">CP500_004960</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP</text>
            <dbReference type="Rhea" id="RHEA:23864"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="4.6.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="7">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the IspF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.12" evidence="3 7 8"/>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56509">
        <property type="protein sequence ID" value="PHX56509"/>
        <property type="gene ID" value="CP500_004960"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008685">
        <property type="term" value="F:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00554">
        <property type="entry name" value="MECDP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00107">
        <property type="entry name" value="IspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003526">
        <property type="entry name" value="MECDP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020555">
        <property type="entry name" value="MECDP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036571">
        <property type="entry name" value="MECDP_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43181">
        <property type="entry name" value="PTHR43181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02542">
        <property type="entry name" value="YgbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69765">
        <property type="entry name" value="SSF69765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00151">
        <property type="entry name" value="ispF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01350">
        <property type="entry name" value="ISPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YgbB" evidence="9">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="10"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="36"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="58"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="134"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="159" mass="17269" checksum="8295EFF48D51F49D" modified="2018-01-31" version="1">MNIRIGNGYDIHCLVTDRPLILGGVNIPHELGLLGHSDADVLTHAIMDAMLGALSLGDIGHYFPPTDPKWKGADSLVLLEQVNQLILDKGWEIGNIDSVIVAERPKLKPHIGQMRDRLSSVLKLNPDQIGIKATTNEKLGPVGREEGIAAYAVVLLMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F449</accession>
    <name>A0A2G4F449_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fructosamine kinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the fructosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56491">
        <property type="protein sequence ID" value="PHX56491"/>
        <property type="gene ID" value="CP500_005220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="PTHR12149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="338" mass="37372" checksum="98B01EB3BE205AF7" modified="2018-01-31" version="1">MWDKISAQISEVTGDKFAIDNRRSVSGGCINQGYAISSISRTYFAKINQASQVAMFEAEALGLQQMRETQTIRVPQPICWGTEGNSAYIVLEWLDLGGRGDDSAWEEMGRKLAAMHKYTPPSPPLSRGGEEVDSGLFRGGEEVDSGLFRGGEKADSGLFRGGEEANSGLLRGCFGWDVNNTIGSTVQINNWTANWAEFWGEHRIGYQLKLAKSRGGHFPQGERLLEVIPELLAGYEPQPSLVHGDLWGGNAGVTSAGEPVIFDPAMYFGDREVDLAMTELFGGFSAAFYRGYNHVFPLNSGYEQRKILYNLYHILNHFNLFGGSYQSQANQMINRILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F476</accession>
    <name>A0A2G4F476_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56287">
        <property type="protein sequence ID" value="PHX56287"/>
        <property type="gene ID" value="CP500_006250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8790" checksum="D419BC75AD96417A" modified="2018-01-31" version="1">MENAQLLRITIDPNICHSKPCIRGLRYPVEFILELLSSGMSTEEILSDYDDLERDDILAVEMRRRLGLSPYPKIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4D8</accession>
    <name>A0A2G4F4D8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56605">
        <property type="protein sequence ID" value="PHX56605"/>
        <property type="gene ID" value="CP500_004525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10417" checksum="A6CD4C45ED194649" modified="2018-01-31" version="1">MDYHSRSIFDFRLKKATLWLNPRRQIQLLVVVLGRESELVSKILIFGELLAEFKSLVNSDYTNRAQLGNCLFLGAIRQFAIDITEISGLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4H6</accession>
    <name>A0A2G4F4H6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2079 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56611">
        <property type="protein sequence ID" value="PHX56611"/>
        <property type="gene ID" value="CP500_004560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018650">
        <property type="entry name" value="STSV1_Orf64"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09852">
        <property type="entry name" value="DUF2079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="474" mass="53434" checksum="11407C6047EBF00C" modified="2018-01-31" version="1">MIVVTTIVLFAASSARHALFHSTAYDLAIFDQAIYLISQNQTPFSSLMAINILGDHTAFIFYPLALLYKIYPDVHWLLFVQAISLALGAWPSWSLARQAGLNEQKSIAVAAVYLLYPVVFNVNLFDFHPEVIALPAILAAILAARLDKIFWFCAAIGLIISCKAVLSLTVMMMGVWLLIFEKKRNYGLIAIFFGVAWFLIATQVIVPYFNQGKQHAGVGRYQYLGKSVFEIAINLVVKPQLIAGRVFSADTFGYLILLFLPLIWWLSPRHLSPLIGALPVLVMNILSDIEAQRDLIHQYSVPIFPFLLAAVIATLADRQKRGINSGKKDEKIGGFSTYLVLANSQVSKLLILWAILTFLVLAKYGYFWTVYLESMDTWQATRQAIYLVQTKGSVLTDNSLATHLAHRSKIKLLHQVSTEQDLREFDYVLLNLRHPWPDTKQTAISVVAQLKKSPLFKISYEKDDVLLFQKYAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4M6</accession>
    <name>A0A2G4F4M6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid oxidation protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56743">
        <property type="protein sequence ID" value="PHX56743"/>
        <property type="gene ID" value="CP500_003795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="16012" checksum="16A68C400D4233D7" modified="2018-01-31" version="1">MSAKDIFHDTVRLALEKDGWTITHDPLFLKVTSKVKMQIDLGAEKLLSAERGMHKIAVEVKSFVGLSALSEFHTAVGQFLNYRVALEKMESERVLYLAVPTDIYQDFFTDSFVQTVLERYQIKMLVFHVKGQEITLWKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4N0</accession>
    <name>A0A2G4F4N0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56710">
        <property type="protein sequence ID" value="PHX56710"/>
        <property type="gene ID" value="CP500_003590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="98" mass="10902" checksum="31583D462A7176FB" modified="2018-01-31" version="1">MSIYVGNLSYDVTQEHLNDTFGAYGTVKRVQLPTDRETGRMRGFAFVEMESEAQETAAIEALDGAEWMGRDLKVNKAKPREERGNNAGGGWGGARNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4U1</accession>
    <name>A0A2G4F4U1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR02450 family Trp-rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56766">
        <property type="protein sequence ID" value="PHX56766"/>
        <property type="gene ID" value="CP500_003930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012663">
        <property type="entry name" value="CHP02450_Tryp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09493">
        <property type="entry name" value="DUF2389"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02450">
        <property type="entry name" value="TIGR02450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="10286" checksum="4BE58ABF126271B7" modified="2018-01-31" version="1">MPKKQKFPYLVGSRWTALQKTWGWRHFQVVNRKNQGKWVFAEMVAACDPNVRFWLNAQQFKDRSLWQAGWQSTQELEDLESAEQNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F505</accession>
    <name>A0A2G4F505_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flotillin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_003245</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56826">
        <property type="protein sequence ID" value="PHX56826"/>
        <property type="gene ID" value="CP500_003245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017037">
        <property type="entry name" value="UCP035261"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035261">
        <property type="entry name" value="UCP035261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013888680" evidence="3">
        <location>
            <begin position="43"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="4">
        <location>
            <begin position="329"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="724" mass="77395" checksum="3FEAB652D6DC2542" modified="2018-01-31" version="1">MLYSFKPNSKTKVRVLKQLAAAVSAALALGATTSLKPSPVLAASDIPPASQISTQLAAKPQIVLKQLPQTTVAVQTVQMDLFGSIVPIAIGGAIIICIPLFFGGLVVIGDREVGIVSKKFSFGGKSLPPGDLIALNGEAGYQADTLPPGWHWGYWPLQYNVRKESLTVVPQGEIALIIAAGGQSIPPQRILGKVTESDNFQDARKFLKSGGEKGRQLGILTGGSYRINTALFTVITATNAAKHGMTAEQLKLYKIAPDKVGIVTTYDGVPIQDGEIAGAIIPNHDNFQNAQKFVNGGGRRGLQEQVLLSGSWNLNPWFVGVEQAAMTEIPIGYVGAVISYVGQTSEDVSGAAFTHGNLVNVGNKGVWVTPLYPGKHPLNTRILKVELVPTTNIVLNWSSKTERHSYDSQLSSLTVRSRDGFAFDLEVAQIIHVGALDAPKVISRVGSMQNLVDHVLQPTIGNYFRNSAQAYSVLDFLSARSDRQAEAAEYIKAALRTYDVQAIDTLIGDILPPGELMQTQTDRKIAEEQCKTYEVQQLAQTQRQQLVRETALAEIQQEMVKSEQGVKISELKANSQVKQAQGEAESIRVKGNAQASAYHAGVVALGGSGYTALQLMQIIGDRHVRVVPDVAVSGNGSGGGLVDGLLGMMMWNQTSKNGENGGELPVGKLPKSESPVLEPAANLPVAKVPSVKPPASRANSPVAKSEADIESLFDELPFDDRSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F529</accession>
    <name>A0A2G4F529_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biopolymer transporter ExbD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_003365</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56848">
        <property type="protein sequence ID" value="PHX56848"/>
        <property type="gene ID" value="CP500_003365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="151"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="232" mass="24963" checksum="1D9C0E1F1BD000E7" modified="2018-01-31" version="1">MKIHLDTPTEEARIELVPLIDVIFCILTFFLLAALQLTRQQAINVDLPKAKTGQTQMREMLIVSIDDFGQTYIDQLPVNYQQLDRVLKSFHNKNPAGLTVLYAPQNAKYAKVVEVLDKLREVGGDRVALATLPSSAPSPQPNPSVPNSGIPAAPPTGNQVQPLQSPLATPLNPSGSQFQVPSQQQQFNPNQFQSPLPTPSQGVNKSPVSPAPTAPNIGPGVATPSQNVAPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F532</accession>
    <name>A0A2G4F532_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Penicillin-binding protein activator LpoB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56597">
        <property type="protein sequence ID" value="PHX56597"/>
        <property type="gene ID" value="CP500_004470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005534">
        <property type="entry name" value="Curli_assmbl/transp-comp_CsgG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03783">
        <property type="entry name" value="CsgG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013754098" evidence="1">
        <location>
            <begin position="29"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="232" mass="23923" checksum="C73D30F7E3FD088E" modified="2018-01-31" version="1">MKTTRMSRLTTISLAALMLAGVSVNAIATPATTQPTTLQTAQATAKKRLVVMDFDYGTTNSYYSSYRGVGAAKGISELLINELVNNGTYTVVDRSKIEQALKKQNHTGAIDAGTAAEIGKQLGVDAVLIGTITKFNVDKQSGGGSFMGIGGGSSKTKAIVQIDVRLISTASGDILATAKAVGEADQSDSSISIRGIGGNSSSNNEDSLLSAAVDKAVSQMVTKLAELSKKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F565</accession>
    <name>A0A2G4F565_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NodU/CmcH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56878">
        <property type="protein sequence ID" value="PHX56878"/>
        <property type="gene ID" value="CP500_003125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031730">
        <property type="entry name" value="Carbam_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038152">
        <property type="entry name" value="Carbam_trans_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003696">
        <property type="entry name" value="Carbtransf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16861">
        <property type="entry name" value="Carbam_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02543">
        <property type="entry name" value="Carbam_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbam_trans_N" evidence="2">
        <location>
            <begin position="132"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Carbam_trans_C" evidence="3">
        <location>
            <begin position="381"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="551" mass="61334" checksum="B244986F5C307C9E" modified="2018-01-31" version="1">MHDSLWIVELICVTKVWSQIDWSVSMAIDSQLIGVSLAFNFHDSNCALSIGNTIVATLELERLFRSKRMSASIAHMELAVNYLLHCYNLRSSQIDYLVVNALNNPFDQVSSNKDIREATYRFLGKDHLTYVVRHHLAHAGYFYFSPFRRALICSCDGGGDLGERVTYFLGDGACLERLEIEVSRHTSTKPYGQFSSFLYGEAFCEGKLMALSSFGATSERIIELVNSIFPKLRNVLFSEGQGLLNETFQGFQGMAQSDPIQAADLAYAVQEEFVRRRVSDIKSVFIPEYKNLVLVGGSALNLSCNTSILNEVTKNVYIPPCCDDTGIAAGQCAVVIANLLGVRATFNLPYMSVDENNLERSRYFGSASAQHNLVQDVTVAAKQLAEGALCLTHIGRPEVGPRALGHRSFLIGAGDIRQRESVSSTIKKREWYRPVAPIILAEDATEYFFGGPNESPYMLYSYHATDTGKEFIPAGLHIDGTARVQTVTKEDDETLYRLLIEYKKITGVGVLLNTSLNLKGQPLSNFAFDTLEISRKINMKSFILTNEESEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5D3</accession>
    <name>A0A2G4F5D3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56949">
        <property type="protein sequence ID" value="PHX56949"/>
        <property type="gene ID" value="CP500_002935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7026" checksum="1743BC332FB2C8D3" modified="2018-01-31" version="1">MTNSPKFQMRLSTRIFWAILAITLLVWILRGVGLLTFIPGAVIWILILLSFVAGILSTLLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5E6</accession>
    <name>A0A2G4F5E6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56958">
        <property type="protein sequence ID" value="PHX56958"/>
        <property type="gene ID" value="CP500_002405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7377" checksum="D3285F25888A262C" modified="2018-01-31" version="1">MNRQDACSTKSEFSCGTGILPVVDRSARCEFNPTTDRRVNFLVEQASCLLLIVVQDVNSTQQLIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5F2</accession>
    <name>A0A2G4F5F2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF305 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57014">
        <property type="protein sequence ID" value="PHX57014"/>
        <property type="gene ID" value="CP500_002165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005183">
        <property type="entry name" value="DUF305"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03713">
        <property type="entry name" value="DUF305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013727331" evidence="1">
        <location>
            <begin position="28"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="DUF305" evidence="2">
        <location>
            <begin position="79"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="235" mass="26202" checksum="A1455420DD7DD811" modified="2018-01-31" version="1">MKPISLKTGFAALTFTCTAALTSGVLAACSKAPLSQTQAPNITAATEANNKQDVAQGGGMAGMNHSMSMDLGPADANYDLRFIDGMTVHHQGAVNMAQDVLNKSKRPEMKKLATNIIAAQKREISQMKEWRKTWYAKADNTPMAYHAQMGHMMAMTPEQMQSMMMSMDLGAADNQFDLRFINAMIPHHEGALVMAEDALKKSKRPEMKKLSQEILTSQKQEIQQMKEWRKTWYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5K3</accession>
    <name>A0A2G4F5K3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Photosystem II reaction center Psb28 protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Photosystem II 13 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Photosystem II reaction center W protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">psb28</name>
        <name evidence="7" type="ORF">CP500_003870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Part of the photosystem II complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cellular thylakoid membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the Psb28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56757">
        <property type="protein sequence ID" value="PHX56757"/>
        <property type="gene ID" value="CP500_003870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01370">
        <property type="entry name" value="PSII_Psb28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038676">
        <property type="entry name" value="Psb28_c1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005610">
        <property type="entry name" value="PSII_Psb28_class-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34963">
        <property type="entry name" value="PTHR34963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03912">
        <property type="entry name" value="Psb28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03047">
        <property type="entry name" value="PS_II_psb28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 4 5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="3 4 5" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12499" checksum="658E87356D79D7BF" modified="2018-01-31" version="1">MAKIQFSRGTDEDSVPEVRLTRSKSGSQGRATFIFENPKALTTSTEDITGMYMIDEEGEIITREVKAKFINGQPAGLEALYLMKSAEEWERFMRFMERYSEAKGLGFNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5L4</accession>
    <name>A0A2G4F5L4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenylate/guanylate cyclase domain-containing response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_001925</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57062">
        <property type="protein sequence ID" value="PHX57062"/>
        <property type="gene ID" value="CP500_001925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="3">
        <location>
            <begin position="193"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="441" mass="49333" checksum="6DB6E3E34524040A" modified="2018-01-31" version="1">MSNKSPCILLVDDEPANLILLEELLHLKGYATVSAVSGDEALSIAQTDRPDLILLDIMMPDLDGFDVCNRLRKDPTLQTVPVIFLTALDDDTSRLKGLEMMADDYLTKPFNSRLLLAKVESVLQLSQMRSQAVSSQFDQVKEQSKRQIAAAWEANEYLAEKFHLFVPEQLLERIAPQGIESIQLGNVTEEELTILFCDIRGFTAIAESQEARETFEWLNALFTKMSDCISSHGGFIDKYLGDAIMAVFDQPNSHARDAIEASVAMQESLQEFNADRHKYNLSSPVNIGTGIHTGICMIGTLGSDRRMDSTVIGDVVNTASRLENLTKVYGCQIIVSESAIVHAREFVNPTSNNYYYRWIDRVTPRGKQQAIEIYEIWTNSSPDCEVKQLTQALFNKGIQGWQSAKFVAALGYFQQLAAQNPVDTVVNLYIERCQEKLGLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Q9</accession>
    <name>A0A2G4F5Q9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56817">
        <property type="protein sequence ID" value="PHX56817"/>
        <property type="gene ID" value="CP500_003540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8847" checksum="437EF8504A800831" modified="2018-01-31" version="1">MKVSISLPDELVRYIDQRVENRSRLVEVLLQAWRKQQEQQAMVEACLLLDELSDELTDEDEAWQQAAITDWEASGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5S0</accession>
    <name>A0A2G4F5S0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57088">
        <property type="protein sequence ID" value="PHX57088"/>
        <property type="gene ID" value="CP500_002070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009387">
        <property type="entry name" value="HigB-2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06296">
        <property type="entry name" value="RelE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="14164" checksum="8E85DF8FBAE55ECB" modified="2018-01-31" version="1">MMSEQPLIQVEAAPTFTRNLRNLAKKYRSIRNDIQPVIEQLEQGELPGDRISGIGYDVFKVRVRNSDIQKGKSGGYRLIYYVKTENGIILLTVYTKSAQADIPADELTGIILEYERRAGEDEEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5X4</accession>
    <name>A0A2G4F5X4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytidine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_001835</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57160">
        <property type="protein sequence ID" value="PHX57160"/>
        <property type="gene ID" value="CP500_001835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016473">
        <property type="entry name" value="dCMP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="PTHR11086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006019">
        <property type="entry name" value="dCMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="7">
        <location>
            <begin position="15"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="20007" checksum="BC16D056DF67C663" modified="2018-01-31" version="1">MENTPDNYEPPQRPDWDEYFLMLAKLAATRSTCLAFPVGAVIAKNRQILATGYNGSPSGSAHCTTQGFCYPGLSSCDASKILPSRAVHAEANAIAKAAKHGISTAGATIYVTLEPCIYCLKLVIAAGIREIFYETSFNSGEKAALRDTFISEGIVELKQIQVSEDTAKKAALFLLSPTSVLKDVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Y8</accession>
    <name>A0A2G4F5Y8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Adenylate/guanylate cyclase with GAF sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_001535</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57111">
        <property type="protein sequence ID" value="PHX57111"/>
        <property type="gene ID" value="CP500_001535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="14"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="7">
        <location>
            <begin position="375"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="132"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="549" mass="61584" checksum="0378AA0CC35D9E8F" modified="2018-01-31" version="1">MQMKTNKTDNYQADILVVDDTPDNLRLLIRILQKQGYKVRPVTNGFSALEAIQSSRPDLILLDIMMPDISGYEICQKLKSEPHLMEIPIIFLSALEDGLNKAKAFEVGGSDYITKPLQVKEVLARVNNQLMVRSLQTQLQAKNHKLMEQNDQLQEEIAERQRVEMETRLLLKATQAISKSEDVESAIDVILGLICETIEWNLAEAWIPDSDGKILKCARGKYASDVSFSEFRQTSLTLTFAPGIGMVGRIFLSQQPEWIEDVSQVQEDVFSRFENAGNVGLKAAVGLPIMADEQVLAVVIFYCDKSLECQPRLLELFSAVATQLGLLIKRKQAESALRWQQQQTEKLLLNILPKPIALRLQKEQKLIADHFDEVTVLFADLVGFTEFSAQKSPTQLVEILNGIFCEFDRLSESRGLEKIKTIGDAYMVVGGLPTPRDDHGEAIALLALEMQAALTQFNLKIGENFQLQIGMHSGSVVAGIIGISKFSYDLWGDTVNVASRMESNGESGKIQVTAATYERLKDMFVFEERGMVEVKGKGKMLTYWLLDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Z0</accession>
    <name>A0A2G4F5Z0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hybrid sensor histidine kinase/response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_001550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57168">
        <property type="protein sequence ID" value="PHX57168"/>
        <property type="gene ID" value="CP500_001550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="12"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="264"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="475" mass="53224" checksum="5210D08E768A25EF" modified="2018-01-31" version="1">MISNSKTTHQGNILVVDDTPENLHLLSGILSKNGYQVRPVPNGKLALSAAQRIPPDLVLLDIMMPEMDGYQVCQQLKANEATKDIPVIFISAINDVMDKVKAFAVGGVDFITKPFQLEEVLARIKTHLKICSLQNSLQERNEDLATAIQELQATQEHLIQSEKMAALGQLIAGIAHEINTPLGIIGSSIDNIANFWEENLENLPQFFQKTSSTSQVYFLKLLYRSSIDRETIFTSKEKRKFKQNLVNYLIEKKVESAEEIADTLVDMEIYDDLEELLPLFQLPDWAIVLNTAYQFTSFKKSISLIQRATAKSGKVVFALKSYAHFDSKQEKVEANLHSGIETVLTLYQNQLKHGIEVVRKYGDLPKILCYPDELNQVWTNLVHNALQAMNYKGTLTIETQFMDGNLSIKFIDNGKGIPPEIVPKIFQPFFTTKPAGEGSGLGLDIVRKIIDKHQGNISVESVPGETIFTVSLPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F681</accession>
    <name>A0A2G4F681_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_001385</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245900">
        <property type="entry name" value="M.Tbo703ORF1385P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57201">
        <property type="protein sequence ID" value="PHX57201"/>
        <property type="gene ID" value="CP500_001385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="391" mass="43968" checksum="5DE7FDBC76B0E328" modified="2018-01-31" version="1">MEAIQLSLFSNELELIPAKKQKKAKLGRYERIQRELESNDCDPYKIFIDIQSQSLPKSDYTFVDLFCGAGGMTQGLLQAGFRPVASVEINPIASATHTKNFPDCHHLCDDIKNLNPQKLLAEIGSPQVHVVVGGPPCQGFSVAGKRDPNDPRNRLFREFVRVVSEIRPWYVVMENVPGILTIQKGSVKQAICEAFQEIGYPHMSVAVLESATYGVPQIRPRAIFIANRFGMENPYPKSQLLPEQYKAIESAIDDLPEYTPIPEINHEWTRHSAEYMERLAKVPPGGSLYESYADAFKRQYPGKPSMTVKENHGGTHIHPHLNRVISAREMARLQTFPDSFIFEGSMKKAMWQIGNAVPPRLAECIGFALIPYLIDIAFNKFKQPEITVLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6A0</accession>
    <name>A0A2G4F6A0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015178207.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57278">
        <property type="protein sequence ID" value="PHX57278"/>
        <property type="gene ID" value="CP500_001165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="83" mass="9728" checksum="454250A65E6C7A5F" modified="2018-01-31" version="1">MTDYILLKAAERYLSRMQPDDQVRIVKALDTLVSDDRGLDIKQLKGRPELRLRVGKYRILFVEDRENQVYVVTAINSRGDVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6G8</accession>
    <name>A0A2G4F6G8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57339">
        <property type="protein sequence ID" value="PHX57339"/>
        <property type="gene ID" value="CP500_000740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="9319" checksum="AC75F41C3C031D6C" modified="2018-01-31" version="1">MLPHELQGIFPESTPAAESLQENQIVRDFYSEVKYRQELEQHCQWYYATAKQHQQELQKMQGDFNIFGWFCRGRHKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUE4</accession>
    <name>A0A2G4EUE4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3352 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_023005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000257">
        <property type="protein sequence ID" value="PHX53159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53159">
        <property type="protein sequence ID" value="PHX53159"/>
        <property type="gene ID" value="CP500_023005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021787">
        <property type="entry name" value="DUF3352"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11832">
        <property type="entry name" value="DUF3352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013693488" evidence="1">
        <location>
            <begin position="24"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="543" mass="58109" checksum="5D4EB45E94870766" modified="2018-01-31" version="1">MPATKSKLLIAATILVTAGSAGAYFYIQSLTNKVSNPQDSAKVVPDEAMMAAFISPNPQALSQLQLFGTPGAQKLVAENLKTFQDQSLAGTQIDFEKDLKPWLGGVMVALLPPDGEAKTKPLQLLLVVSVKNKISAWNFANRLKSQPGTKIQESEYQGVKIAEIVETSGKAYSVALLDDQLAIAPLKKTVELAIETFKGQPSLATQQNASKFLSESAGVSNPIATVYIPDYPAAMEQLQANLQPDVKLSSTVISQFKQVKSMVAGIGVDTAGLRVKTIAQLDPKFAQQNPQVASKLLPKFPGETLALVGGKGIDKFWSEATAEAKNSPELTNSMKQIRDGLKGVNLDADRDVFGWMNGEFAIGAIASNQGILSQFGMGATMIFETSDRPAAEAMLKKLDAIAKSNPTVSIAPRQVQGKEVTEWKIPQQGTLFGHGWLDKNTMFVAFGGPLVDMISATPPQPLSSSSNFKAIATSVSPGDRGYFYLDMDKTMSWANQYLLKAAPTLVSPPTAEVLNSIRGVSVVTTSPDPSSAQVEMLFSFKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUH0</accession>
    <name>A0A2G4EUH0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Penicillin-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_023120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000267">
        <property type="protein sequence ID" value="PHX53138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53138">
        <property type="protein sequence ID" value="PHX53138"/>
        <property type="gene ID" value="CP500_023120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="5">
        <location>
            <begin position="103"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="4">
        <location>
            <begin position="301"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="625" mass="68947" checksum="3C6BD4EBCF77465B" modified="2018-01-31" version="1">MTYDPRFDRYRSPNSKRSKQPDDRTRSPKPTKSPVSGNPSRQPRWPMERLKRSKFRLWVVWAVLMFSGLGLAVNLFYLQVTRASALQKQAQQQQTLKTKPFVPRRPIIDRSGNVLAIDRQVYTLYAHPKLFKHTKAQIAASLAPMLPIKASAGNTAETELLQKFNLAESGITIADSLAQEVADRVSRMLIKNSPVDGLELVRQQQRFYPQQELVADVLGYVDGERKGQAGVEYSQQNLLERSMPSIQFTKSINGNWLPDRLAAGFVQFDDLKLQLTIDSRLQRAARIALKDKMKEHGAKRGTVIVMDARNGELLSMVAEPSYDPNKYFDFGLERYKNWAVTDVYEPGSTFKAINVAIALEAGVVKPDTVFNDEGRIYMNPWTIQNSDYQQAGARGPSTVTKILKNSSNVGMVHVMSKMKSSVYYQALEKLGLGQSAGTDLPFEVTSQLKNREQFINSPVEVATTAFGQGFSITPIQLVQLNGALANGGKLVTPHVVRGLFNREGEAYWKLPRSVGKQVFSPETTKQVLEMMESVVDGGTGKAAQISGYRIAGKTGTAQKASVGGYSKAIITSFVGIMPVEAPRYVVLAVVDEPKGGSGGTVAAPIVESVMEALISIEKIPPGKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUH9</accession>
    <name>A0A2G4EUH9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="6">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_022860</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000249">
        <property type="protein sequence ID" value="PHX53184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53184">
        <property type="protein sequence ID" value="PHX53184"/>
        <property type="gene ID" value="CP500_022860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022337">
        <property type="entry name" value="Inositol_monophosphatase_SuhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01959">
        <property type="entry name" value="SBIMPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="271" mass="28875" checksum="8C7589257D07EF9D" modified="2018-01-31" version="1">MTNNELQNLLEIATVAALAAGAVLQSFCGKLSEIEEKGRSGDLVTEADKASEAVILEILGRHVPDHAILAEESGKLGNASSKYLWAIDPLDGTTNYAHQYPFACVSIGLLIEGIPQIGVIFDPFHNELFAAAKGLGATRNRRAIEVSQISELTKSLLVTGFAYDRRETADNNYAEFCHLTHLTQGVRRSGSAALDLAHVACGRLDGYWERGLSPWDIAAGVLIVSEAGGQVTAYDGSAFEINSGRVLATNGKIHADLGDALLKTPPLSSWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUK3</accession>
    <name>A0A2G4EUK3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000238">
        <property type="protein sequence ID" value="PHX53219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53219">
        <property type="protein sequence ID" value="PHX53219"/>
        <property type="gene ID" value="CP500_022655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="29"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="669" mass="75533" checksum="8FBC0CF18846F57A" modified="2018-01-31" version="1">MNPQPWRLRLTWIDTVTGDRRSPIFDLPIALGRVFEAMPATINSERVSRIPLKSSQVSRFHAVITSEADSSIVVTDTGSSNGTFVNGIKTNRCVLTNGDMLQIGPYAIAISFAVNSTETPPVNNSHIFFNPQTNRPDSAIKQPAVLPPSPKISTGEFPPIAFLHASEVTMRSIQSMGTPVEEMDWAAIGGGLGSFIWVDLLRICGVKADRIAVLGMENQPYARYRQLCLNSQIPLYERLRSNSDSCPDNIWGWPPYAVREAWQELRKGRLDVSLKLMWQVFAEPTFAETYTPRAENVFDSIDREVSRIGWNQMFRYGRVRGIRKTDDGRYAIAYSRSNSQQREHAFLIAKYVHLATGYPAIQFLPDLQAYRETTQDFKSVVNAYENHDEVYQQLEARGGSVLLRGRGIVASRVVQRLYEARQQNRNIQVLHLMRSPKPVGNKFNFAERSVENHYEFQPFNWPKACWGGELRVVLENASPEFIPQLLTDWGGTTTANRGDWRRMVKEGLSQGWYQITFGEVERVERDSQNRTVTYIREKELKGQIELKADFIIDATGLDAKVKNSPLLDDLVVQYNLDLNRLGRLSVEKDFEVPEMRNSSVSNGDGRMYAAGAITLGGHYAPVDSFLGLQYAGLRSVESLAKAKVPGVGKLSILRSLIQWLKWIFNQSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUL3</accession>
    <name>A0A2G4EUL3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3727 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0473 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000235">
        <property type="protein sequence ID" value="PHX53229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53229">
        <property type="protein sequence ID" value="PHX53229"/>
        <property type="gene ID" value="CP500_022595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022203">
        <property type="entry name" value="DUF3727"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009711">
        <property type="entry name" value="UPF0473"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06949">
        <property type="entry name" value="DUF1292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12527">
        <property type="entry name" value="DUF3727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="22135" checksum="7D84D7ABF7F9706E" modified="2018-01-31" version="1">MSSSPYRKENGKSDPVSVTLTDEFGRSLTCNIEYSMDLEGQEYALLLPIDSPVEIFTWNEDDADEAAIPVEDETEIDKIFDTARVVLQEQNLKLRRTAVTLTVIGELPDFPDENLEPDADPDEESDFEELMWLTSFYHEEQEYAIYTPLDPFFILARMNDDGKPELLSEEEFQRLEPMLPMLEDQFFDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUN0</accession>
    <name>A0A2G4EUN0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_023100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000265">
        <property type="protein sequence ID" value="PHX53140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53140">
        <property type="protein sequence ID" value="PHX53140"/>
        <property type="gene ID" value="CP500_023100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="208"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="332"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="549" mass="62479" checksum="C73D1FDDB861EBC3" modified="2018-01-31" version="1">MIVFEKPELLNESAQRTELIEQLLDIGAALSSAQDLGDLLNLILSKSREITYSDAGSVYLVDHSDETSKLLFKVAQNASKPELSFREFALPLTDKSLAGYVAITGQGLNLSDAYDLPSGVPYQLDTSFDRDINYRTCSVMVLPMENRQGETIGVLQLINRKTKAETMLTAENAWESTQHYSEWEERIVRSLASQAAISIERNQLQESIEHLFEGFVKASVQVIEARDPCTYGHSERVAALTVRLSEEVNTTSSGWLRPIYFNTRQIQEIRYAALLHDFGKIGVPEAILTKQKKLYPSQLEIIRHRFALAQRTMEMECVQSKYKYLLEHSAYRKHPTQELGCAQCQEIEQLDTKLAETKTRLAEYWEVLLKANEPHILTEEPIAQLRELSRQTYRDLDGATKPLLTQEEILQLMVSRGSLTLEERAVIESHVTQTYEFLKQIPWTKDLKNVPDIAYGHHEKLDGTGYPQGLKQSEIPIQAQMMTIADIYDALTAGDRPYKRALRIDAAIKILRQEAAHNKINSDLLELFEHRQVFGVLGHHLDVHQVELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUN8</accession>
    <name>A0A2G4EUN8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000231">
        <property type="protein sequence ID" value="PHX53244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53244">
        <property type="protein sequence ID" value="PHX53244"/>
        <property type="gene ID" value="CP500_022530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013727328" evidence="1">
        <location>
            <begin position="30"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="600"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="871" mass="96487" checksum="FBA1ECF8B22B9DBF" modified="2018-01-31" version="1">MKFTRSLRQAILLFLISCLLTISIPPVFAQVQPTDGMQLVRQARSLYNSERFSEVVPLLQQAAVAFELKGENLNRATALSNLAASFGQLTEWEQAEIAVNSSLSVVRQLPKTIEQQGILGLSLNIQGQLQLERGRTQEAIDIWTQAAKIFEQIDAKDQLFQIQINQSLAWESLGLYPRSCKVLLGSLKLENKICEVSNASLASLKNQSISPESIRGINALGRVLRVLGKLDRSQEILSVGLEVAKNLGLRQEEAAIYLNLGNTERAKSNKSGLSPQQRADLERSALLYYARSDGASTGASPLRMQAKLNQLSLLADRENWSEAGVLWRSIQPQVAQFPSNRAGLYARINLAESSIKLAQSPIATPSLSNIDKMLSEALEPAHRLGDKRIQAYILGTRGKLYELQKQPSMAENLTIQALSLAPAFQSPDIAYQLLWQLGRIRKAQGNLEGAIAQYNQAVNVLSSLRGDLVTVNPEVQFSFRESAEPVYRQLVELLLEEESPSQDKLKQARQTIESLQLAELDNFFRDACADAKPKSIEEIDPTAAVIYPIILSDRLEVILSIPGKPLRRYSTKKSQEELETVFRQAKNAIRPAAFPRDRLPPVQQVYDWLIRPAEADLTASGIKTLVFVLDGYLRNLPMAILHDGEQFLAEKYSLALAPGLQLLAPKPLSKVKLKVLTAALSEARQGFSALPGVKREIQQISTQMPTNGLLNQQFVSGELQARIKEVSYPIVHLATHGQFSSNAADTFIVTWDDRVNVKEFDRLLRSRTGEKQQAIELLVLSACETASGDSRAALGLAGAAIRSGARSTVATLWQVNDESTAIFMAEFYRQLALSTISKAEALRNAQLTLLNNPLYKNPYFWAPFILVGNWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUR5</accession>
    <name>A0A2G4EUR5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_022735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000243">
        <property type="protein sequence ID" value="PHX53206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53206">
        <property type="protein sequence ID" value="PHX53206"/>
        <property type="gene ID" value="CP500_022735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="7">
        <location>
            <begin position="15"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="849" mass="93738" checksum="31A7B413CB7773D6" modified="2018-01-31" version="1">MAKQLNLLSGQVISTALHAEMQQSYLEYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDRPYRKCARVVGDVLGKYHPHGDQSVYDALVRMVQEFSSRYPLVAGHGNFGSVDNDPAAAMRYTETRLASIAHEAMLTFVGDATVDFTPNFDSSQQEPTVLPAQLPFLLLNGCTGIAVGMATNIPPHNLGEVVDGLIALIENPELSDEKLIELIPGPDFPTAGEIIATEGIVDAYTKGKGSIAVRGVVGVEEVVGNRKIKTKTALVVTEFPFQVNKAAWIEKVAELVNAGRLDGIADLRDESDRDGIRVVIELKREFAPETVLARLYQQTDLQTNFGAILLAIVNGQPRQLTLRQLLREFLDFREVTLTRRYNYELEVAERRCHIVEGLMLALTNLDVAIDILRNAPDGTTAKANFQIRLNLSESQCDAILSMPMRRLTGLERQNLQSELDELVAKIQELQRLLGDRHEFLKALKKEFRSLKRKYNDPRRTKLVNGAGRAAKEESKLSGKNKSVLPLSTPELSTPQLLPILEVEETIVEFSHKHYVRRLPAGGSYRAKSQKSVQALEKNEDFIVTATQTKTDRNLVVLIPSGKAYPLKVADIPTSTGRDRGTPIVSLLSPSAAKESAGRTFSELTVAHFVLPENSEATDLVTLTQQGKIKRLQLSEFADLTNRGVTVVKLKEDDRLRWASLTKVGEQVAIATTGGRVLRFEVNDEQLPPMGRTAQGSQATRLRKQEELVGCVTVNPDDSLVLFSELGWAKRMPAGSVRLTNRGEIGTQAFRFAEPKDVLVGLLRAVPGSDVKLLTNTGRFLRSTTDAIAFWGKDAAGERVFDLNPAEKIIKVISCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUU2</accession>
    <name>A0A2G4EUU2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta</fullName>
            <shortName evidence="13">ACCase subunit beta</shortName>
            <shortName evidence="13">Acetyl-CoA carboxylase carboxyltransferase subunit beta</shortName>
            <ecNumber evidence="13">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">accD</name>
        <name evidence="16" type="ORF">CP500_022205</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the AccD/PCCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="13"/>
    <dbReference type="EMBL" id="NXIB02000218">
        <property type="protein sequence ID" value="PHX53309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53309">
        <property type="protein sequence ID" value="PHX53309"/>
        <property type="gene ID" value="CP500_022205"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01395">
        <property type="entry name" value="AcetylCoA_CT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041010">
        <property type="entry name" value="Znf-ACC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17848">
        <property type="entry name" value="zf-ACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00515">
        <property type="entry name" value="accD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="15">
        <location>
            <begin position="29"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="287"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX53309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="316" mass="35410" checksum="D0DF06AB4B8DDA43" modified="2018-01-31" version="1">MSLFDWFANRRKSVPNSQERPEREIADGLWNKCESCGALSYTKDLRANQMVCLECGHHIRVYSDDRIEQLIDANTWMPINEGLHATDPLKFRDRKKYSDRLREFQEKTGHLDAVETGIGKLETLPVALGVMEFQFIGGSMGSVVGEKLTRLIEHGTREHLPVIIVCASGGARMQEGMLSLMQMAKISGALERHREARQLYIAILTHPTTGGVTASFAMLGDITIAEPKATVAFTGGRVIEQTLREKLPENYQTSEYSFAHGFVDLIVPRTQLKKTLAQLIALHQPQDKLGRSQSEELEPADTHVFPPQTHAFELSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUV6</accession>
    <name>A0A2G4EUV6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ORF">CP500_022160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000217">
        <property type="protein sequence ID" value="PHX53314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53314">
        <property type="protein sequence ID" value="PHX53314"/>
        <property type="gene ID" value="CP500_022160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="20"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="163"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="211"/>
            <end position="214"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="293"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="344" mass="36472" checksum="E0307824F20A7EE5" modified="2018-01-31" version="1">MGLLNRFSLSRNDMGIDLGTANTLVYVSGKGIVLQEPSVVAIDQDLKIPLAVGEEAKKMLGRTPGNVIAVRPLRDGVIADFDMAELMLKTFISRVRGKTLSQPRIIIGIPSGITGVERRAVIEAATQAGASEVRLIDEPIAAAIGAGLPVSEATGNMIIDIGGGTTEVAVLSLQGTVISESVRVAGDELNEAIIQYVKKVHNLVIGERTAEEIKIQVGSAYPTPEDNEVVMEVRGLHLLSGLPRTVTIKGPEIRESMSEPLSVIVEAVKRTLERTPPELAADIIDRGIMLAGGGALMRGLDTLISHETGIVTHVAADPLCCVVLGAGRVLENKMLERVFSGQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV25</accession>
    <name>A0A2G4EV25_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family intramembrane serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_021760</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000204">
        <property type="protein sequence ID" value="PHX53389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53389">
        <property type="protein sequence ID" value="PHX53389"/>
        <property type="gene ID" value="CP500_021760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="58"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="196" mass="21370" checksum="6DECB9A0E325B8E8" modified="2018-01-31" version="1">MSNPETKSITRELQSHAAILGSCVALLWIIEIVDVFLFRGGLNSYGVRPRSLDGLEGILFMPFLHGSFAHLAGNTLPFLTFGWLIMLRKISDFFVVSAVTMLVSGLGVWLTGAPNSVHIGASGLIFGYFGFLLLRGLFERSFTSLLISLVVGFFYGSLIWGVLPSQPGVSWQAHFFGFAGGVLAAQLLGRQKREIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV30</accession>
    <name>A0A2G4EV30_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53402">
        <property type="protein sequence ID" value="PHX53402"/>
        <property type="gene ID" value="CP500_021655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="487" mass="56100" checksum="EB990738B1022FA8" modified="2018-01-31" version="1">MSDSNISLIVITYEDWQSWRSSCCYKKEWPGCDWAYFLKAGEAIQKLDVEKCKRIYVSPQAKVSEVIREARKHFAGFDKDRWEPSQNFYGYKEDPDFDYAISYSMYYPAANDGIVSEDTRISKLGILEDDLIVIQKINHKPYNFHVSYCMAFVKHFDDFQEMVLNGKDSRKDRHTSFSRDTKFDVVLLYTDEDVELAKYIRGHLDELHQMSGSDTTVYVVEAPHGKIHAAEFWKARLEQKAYYAWSLLGWTRSSPYNKSETYKIARSLGIYPNTFPCLVVSHKSNYQNKVTLPIFSNFSKFFRNFFTNMQRSVDELENGATFSQQELLSQLRNAMEQVERDEPIEKQPKTARNLPPGVIIMAEKPIFNINQQGATIGVGVATEGSNVRFVQHAKQNVNIPEQDLVEATQKIQDLLSQLSLSYPIINTDEQETFIQKFVGLLESTPDLVKVIFAGGIEGLKILCPPAGIPIEMTRRLYDSLQERYAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV72</accession>
    <name>A0A2G4EV72_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">aroA</name>
        <name evidence="9" type="ORF">CP500_021600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000200">
        <property type="protein sequence ID" value="PHX53425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53425">
        <property type="protein sequence ID" value="PHX53425"/>
        <property type="gene ID" value="CP500_021600"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="27"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="38"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="109"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="451" mass="47387" checksum="00F6FB08081418B2" modified="2018-01-31" version="1">MQAAIITTTQIGESQTLSIQTPASGLSLTGRIRIPGDKSISHRALMLGAIAHGETTIEGLLLGEDPRSTAKCFSLMGAKISELNTELVTVRGVGIGQLEEPVEVLDAGNSGTTMRLMLGILASHPGRFFAVTGDSSLRSRPMSRVIKPLQQMGAQIWGRRDNSLAPLAVMGQQLKGIHYHSPIASAQVKSCILLAGLMAEGETTVTEPALSRDHSERMLRAFGAQLTVDPETCSVTVTGSAQLQGQKVIVPGDISSAAFWLVAGAIVPGSELVVENVGVNPTRTGILEALEMMGAHIELQNQRVAAGEPVADILVRNCGQLRGCTIAGDLIPRLIDEIPILAVAATFASGTTIIRDAAELRVKESDRLAVTAAELNRMGAQITELPDGLEITGGTCLTGADVDSYTDHRIAMSLAIAALNASGTTNIHRAEAAAISYPDFTATLQQVCHPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV90</accession>
    <name>A0A2G4EV90_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53398">
        <property type="protein sequence ID" value="PHX53398"/>
        <property type="gene ID" value="CP500_021635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="11984" checksum="8E436A87D2C09A59" modified="2018-01-31" version="1">MNWKVHIHSNPKIMLGKPVIKGTRISVEFVLGLFSEGWTQQQILENYPTLNPESIKAVFAFAAECLKEEDDSPEDIAEIEAARADYKAGDYTTFDRYMVGRANKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV97</accession>
    <name>A0A2G4EV97_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000195">
        <property type="protein sequence ID" value="PHX53455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53455">
        <property type="protein sequence ID" value="PHX53455"/>
        <property type="gene ID" value="CP500_021405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="10"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="372"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="406"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="440"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="474"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="508"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="576"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="610"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="644"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="728" mass="81378" checksum="1C12E37DA2A88B19" modified="2018-01-31" version="1">MVGQLLDGRYRVVQILSSGAFGQTYLSVDTRRPNHPQCVVKQLRPPSNTSTVLKTAYRLFKQEAEILEKLGKHNQIPFLLAYFEDSNQFYLVEEFVPGQALNREIIAGKPWPEEKVISLLEELLEILMFVHSQGVIHRDVNPSNLIRRKPDGKLVLIDFGSVKEVTIHLSEYDTEFPRTIATGTPAYMPIEQFQGNPQFSSDIYACGMMAIQAITGLPGTDLPKLQDPNPSHTGEIVWRNRAQCSSNLGNIIDKMVCHQFSKRYQSAQEVLEALNKIRHRQDSANNAQNTNAYQPKLTSSGSWLVDSRFWLLALAGLGTALGLILLFSYWNRPNPLKAKEYYEQGLVKSRNQDAAGAVQSFNNSIKFNHNNAEAFYGRANANYDLKKYQESIADYSQAIALNPNYFQAYFNRGLARYDFNDKRGALEDYTQVLSLQPNDVDTYYERGLVYLDLQDYKTAIQDFSEVIRLEPTLAKGYHSRGLARAAAGDLQGAIGDYTEAIRVDAKDTKALYSRGRARFHSGDYKGAFGDYSQVIAIDPNNADAYANRCSTQLNLGLYQAAIDDCTKAISLGDKDAIPYNNRCIAYLNLKDYPKAIEDCTQAVTVNPNDYNAFSNLGLARNAGGDAEGAIADFTSAIGLNPNDAEAYANRAKIYQQLNNYNSAIADYVQAIRINPNYAAAYYGRATVRRSLGDKAGAISDFEKAGKIFLDQGLTRGYKDSQFEIEKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVM8</accession>
    <name>A0A2G4EVM8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53593">
        <property type="protein sequence ID" value="PHX53593"/>
        <property type="gene ID" value="CP500_020690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="10225" checksum="876A4152B117C55F" modified="2018-01-31" version="1">MTIREIAIAKLQELPESFLPEVSEFIDFVMHKHQNRIAQPKIPDDIAKAWAKWFEEVDRLEVTTNQPESEYQQLLLNKYRQQGLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVP2</accession>
    <name>A0A2G4EVP2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chlorophyll A-B binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000234">
        <property type="protein sequence ID" value="PHX53237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53237">
        <property type="protein sequence ID" value="PHX53237"/>
        <property type="gene ID" value="CP500_022585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="50" mass="5593" checksum="16594BD12C5CC021" modified="2018-01-31" version="1">MQDPKRNAWNWGFSEGAENWNGRLAMIGFSAAVIIELVSGQGVLHFWGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVR6</accession>
    <name>A0A2G4EVR6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_022395</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000226">
        <property type="protein sequence ID" value="PHX53267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53267">
        <property type="protein sequence ID" value="PHX53267"/>
        <property type="gene ID" value="CP500_022395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="SSF161084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="55" mass="6037" checksum="7C6593164087ECEC" modified="2018-01-31" version="1">MGLKRGTAVDLLIVAYIVFRLVHSVIHIAGINPIFRLLCLVIQLGCLVALTVMTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVW2</accession>
    <name>A0A2G4EVW2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxysome shell protein CcmK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Carbon dioxide-concentrating mechanism protein CcmK</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ccmK</name>
        <name evidence="7" type="ORF">CP500_020270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the shell proteins of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered. Assembles into hexamers which make sheets that form the facets of the polyhedral carboxysome. The hexamer central pore probably regulates metabolite flux.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer. Interacts with CcmN and CcmO in the carboxysome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Carboxysome</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">The tight homohexamer forms a small pore which is positively charged.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the bacterial microcompartments protein family. CcmK subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial microcompartments protein family. CsoS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000165">
        <property type="protein sequence ID" value="PHX53664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006635058.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000165.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53664">
        <property type="protein sequence ID" value="PHX53664"/>
        <property type="gene ID" value="CP500_020270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00854">
        <property type="entry name" value="CcmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020808">
        <property type="entry name" value="Bact_microcomp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046380">
        <property type="entry name" value="CcmK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044872">
        <property type="entry name" value="CcmK/CsoS1_BMC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00936">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143414">
        <property type="entry name" value="SSF143414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01139">
        <property type="entry name" value="BMC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51930">
        <property type="entry name" value="BMC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="1 5" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="5" id="KW-1282">Carboxysome</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC" evidence="6">
        <location>
            <begin position="4"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="12063" checksum="AC311121E437365E" modified="2018-01-31" version="1">MAIAVGMIETLGFPAVVEAADAMVKAARVTLVGYEKIGSARVTVIVRGDVSEVQASVAAGVESVKRVNGGQVMSTHIIARPHENLEYVLPIRYTEAVEQFREGVSGIRPLNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVX4</accession>
    <name>A0A2G4EVX4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sugar transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000174">
        <property type="protein sequence ID" value="PHX53600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53600">
        <property type="protein sequence ID" value="PHX53600"/>
        <property type="gene ID" value="CP500_020625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="324" mass="37996" checksum="1CD485BFCF12B813" modified="2018-01-31" version="1">MNGICTLANDIVYDQLIALLNSIEIILGSNTPICIYPFDNQIEQIKAEIVNRPNVFIYQDSTSIQRWDKFMESAAPERLNRKKFRLYGAHRRFCAFDDPFEKFIYMDADILVMNSLDPVFQKLEEFDFVVYDFQFGDPTKVYNIQSPKLIEVFDQNRIKSEIFCSGLYGSKQGFFDQNTREWLVAQLQSGDSEILYEGAGEQPLLNYMVMKTNMNSYNFAYSLPDAEKTGCCVSSQHFEERDNILYDKGNRLTYIHYIGVRPDLIRRVCAGENIEFPYRDLFLHYRFLREPSKRPIFNEPPKSYTEVSAPNLLKRVLRRLRINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWA8</accession>
    <name>A0A2G4EWA8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53758">
        <property type="protein sequence ID" value="PHX53758"/>
        <property type="gene ID" value="CP500_019795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="18239" checksum="CE01DEC4733317A7" modified="2018-01-31" version="1">MNRGCRANQTGFVLEKTVAGTLEGHGYLEICPQLPKKRKRDWLLVSTDIPKRYAKQVYIGSSIYETEINVDFYIVDSGAFSQGLIVECKWQEDKGSVDEKYPYLNLNIKSCYRVPTIVIVGGDGMRQGSIDWFKKQIPDNPNLLGVYKLEGFITWANKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWF0</accession>
    <name>A0A2G4EWF0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0235 protein CP500_019145</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0235 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000145">
        <property type="protein sequence ID" value="PHX53882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53882">
        <property type="protein sequence ID" value="PHX53882"/>
        <property type="gene ID" value="CP500_019145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00634">
        <property type="entry name" value="UPF0235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13420">
        <property type="entry name" value="PTHR13420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="SSF69786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8110" checksum="FA1E68D318D75103" modified="2018-01-31" version="1">MMILTVKVKPNSKNQSIEEQPDGSFTVHLKSPPVDGKANQELIVMLAKKFKVPKSSIAIKSGLSSKHKLVEIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWJ9</accession>
    <name>A0A2G4EWJ9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_018970</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53899">
        <property type="protein sequence ID" value="PHX53899"/>
        <property type="gene ID" value="CP500_018970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10" id="KW-0288">FMN</keyword>
    <keyword evidence="9 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="12">
        <location>
            <begin position="30"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX53899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="337" mass="37266" checksum="02EF958AB6DADCBE" modified="2018-01-31" version="1">MLTLSPELQKRLATPLKIGDFEVKSRVLQSPLSGVTDLVFRRLVRRYAPDSMMYTEMVNATGLHYVKQLPRIMEIDPNERPISIQLFDCRPEFLAEAAQKAVAEGADTVDINMGCPVNKITKNGGGSSLLRSPETAEAIVRAVVEAVDVPVTVKTRIGWTDKEINILDFAKRMEDAGAKMITVHGRTRSQGYNGPAKWEWIRRVKEVLSIPVIANGDIFSVEAAMRCLEETGADGVMCSRGTLGYPFLVGEVDYFIKTGVEKITPTPIELLECAKEHLRALWEYKGESGVSQARKHLTWYAKGFPGAAELRGLLAVVETVEQGCDSIDRAIEQLPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWQ2</accession>
    <name>A0A2G4EWQ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53963">
        <property type="protein sequence ID" value="PHX53963"/>
        <property type="gene ID" value="CP500_018695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="96" mass="10994" checksum="B2CEAB9F63F3DF67" modified="2018-01-31" version="1">MQTAQEKQLRYQIQCPGLPLAVYREVAAHLRQVEGVETGLIPQQSQQFDYSDSQVGALWIQYPEGFDLTDRQRVDRILAYYGDRYGAWESLVIGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWQ8</accession>
    <name>A0A2G4EWQ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53959">
        <property type="protein sequence ID" value="PHX53959"/>
        <property type="gene ID" value="CP500_018715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="315" mass="36800" checksum="E79159D211D42CA8" modified="2018-01-31" version="1">MSLNPEQLKKHCEVILQSRRIKNKIVVLCEGVTPKIQGRESPQSYKAMEQMPDSNFYKACVPTWWKQKLPEFFNCGDRKDVIDTYFTLLTLHKQDSTNSYLDCDRLFAMIDLDLHLQAIENYVFTDTEAIFCNLYEKSQVQEQNVAHHRIWITGLIHKEAYFLTPELQSLFDDYPNSPMYQENLASLTNIYSDMADGISSDKDLQFNVKRAFDRINHCSGLDCAELDLGKFQDSWKHQFQNTTDATQKHELIVALLTIKKAKDYWKQIKPPADWSGNEKVFREQLSLEIGRFYSQQSSDVNCHIPFFFKALHELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX10</accession>
    <name>A0A2G4EX10_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PARG_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54006">
        <property type="protein sequence ID" value="PHX54006"/>
        <property type="gene ID" value="CP500_018375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004649">
        <property type="term" value="F:poly(ADP-ribose) glycohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046372">
        <property type="entry name" value="PARG_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05028">
        <property type="entry name" value="PARG_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PARG_cat" evidence="1">
        <location>
            <begin position="201"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="340" mass="38068" checksum="D8483A6D25AA1835" modified="2018-01-31" version="1">MEKAMNDFLDSLICRQTFDTQDLINDHPPKFYNGNKQLVYDICCPPGCNHHGQLAFSRWYAMVLPEYLSSLEHQTDISERKGYFEYEPSEDSTQMEWYLNFAHYELFFAYGSSLFAQDEMQVAEHPALSSLREALLDSKIKSLTVESQQPTPILIRGVERRCAISTDPNSEQGRPFGLYGNNFGRATSDAIEQATKPLNPPTITNIIAMEAPAGGRGYYSMAQIEYILQTAFTGFSAARIESQLELPQAPSLMIHTGFWGCGAYGGNRVLMALLQLLSARLSQVNCLVFHTSDAMGSQDLATAQQILDRDLVPDDSPVKVSDLVEKIHAMEFQWGFSDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX13</accession>
    <name>A0A2G4EX13_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Recombinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54069">
        <property type="protein sequence ID" value="PHX54069"/>
        <property type="gene ID" value="CP500_018045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025827">
        <property type="entry name" value="Zn_ribbon_recom_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13408">
        <property type="entry name" value="Zn_ribbon_recom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51737">
        <property type="entry name" value="RECOMBINASE_DNA_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Recombinase" evidence="1">
        <location>
            <begin position="132"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="426" mass="48697" checksum="90A7B4528EED79CD" modified="2018-01-31" version="1">MKIIAYSYSEPLLESAPAPGFWGQEVDRTYQDLGGRQQLQQLLKDCQTEPVKYLLIQRFEELGDTLQEVCAHLAQLEILGIELIVTDEKPTENRANLLKLLAEIQRSQHSRSIRKGHARNRIKARIPPGKAPYGYRRGKDRYAIDKTTAPTVKDFFEHFLIYGSLRGSVRYLAKKYHKKISVSTGRRWLTNSAYRGDLEYQNGQVISNTHVPIISREEAAQIDRLLRRNRRLPPRTASAPRSLAGLAICAECRSPMTVAKVTAYRKSREYLYLRPINCSRQLKCSGLDYDEVLQLTIAGICQNLPDAVAGLKIPDMNGIKAGIGSAIEFKEQIINQLSALIENGILDTETAELRVYKIRTEIAELQSKLAQLPPVNLRETAQTVSLPQFWLDLSESERRFYFREFIDRIEIVRENATFKLQIIFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX88</accession>
    <name>A0A2G4EX88_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000128">
        <property type="protein sequence ID" value="PHX54060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54060">
        <property type="protein sequence ID" value="PHX54060"/>
        <property type="gene ID" value="CP500_018145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="154" mass="16939" checksum="C8F28C700BA858A9" modified="2018-01-31" version="1">MATATVYPNAPELCTDDYVAVGLATCFVKEEGEVLQVQVIEAIPSAALEAIVKGIPTSYQMICGTTLGAVLDGEALKMLPEFPTSAQFSEEFGFRAIAAARTYKIRPQAQSHIPLGTVRSDFTYSLERKRVLNSQRVVRTEDNVKQHEHTHKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXL8</accession>
    <name>A0A2G4EXL8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cytochrome c-553</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Cytochrome c553</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Soluble cytochrome f</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">petJ</name>
        <name evidence="9" type="ORF">CP500_016970</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cellular thylakoid lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Binds 1 heme c group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome c family. PetJ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54284">
        <property type="protein sequence ID" value="PHX54284"/>
        <property type="gene ID" value="CP500_016970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031979">
        <property type="term" value="C:plasma membrane-derived thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00594">
        <property type="entry name" value="Cytc_PetJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023655">
        <property type="entry name" value="Cyt_C6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008168">
        <property type="entry name" value="Cyt_C_IC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34688">
        <property type="entry name" value="PTHR34688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00605">
        <property type="entry name" value="CYTCHROMECIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013974574" description="Cytochrome c6" evidence="6">
        <location>
            <begin position="26"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="26"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="11736" checksum="61E637915C906644" modified="2018-01-31" version="1" precursor="true">MKRLLSIALLALAIFTVGFGSPALAGDAAKGAKLFQNNCSACHVGGGNVVVRAKTLKTAALEKYGMNSLEAITAQVTKGKNAMPAFGTRLKPKQIEDVATYVLEQAAKNWKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXM1</accession>
    <name>A0A2G4EXM1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_017320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54226">
        <property type="protein sequence ID" value="PHX54226"/>
        <property type="gene ID" value="CP500_017320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="316" mass="33320" checksum="6876AF97700D0452" modified="2018-01-31" version="1">MDLTLFLQQFLNGLSIGSVYAIFALGYTLVFSILGIINFAHGAVFTLGAYFTYALMGGTFGFNGLWANARIPVELPFAVALILGSVMAGLVGVIVERVAFLPLRRRHSDSLLTVVSSLGVAVAIANIIQYLVGAEIYTFPANTYGYLPAAINFGTVDKPIPIRTVQIVIFAVSVAIVAVLTYLINFTKFGKAMQAVAEDATTSSLLGIDTDRYIVLTFFVSSFLAGLAGSLVGSSVSIAGPYFGIAFGLKGLAVIVLGGLGSIPGAVLGGFIIGLVEAFVPGDFSAYKDAVAFAILFMMLLVRPQGLFGRRLIQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXR9</accession>
    <name>A0A2G4EXR9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54276">
        <property type="protein sequence ID" value="PHX54276"/>
        <property type="gene ID" value="CP500_017040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7255" checksum="07F85FBF94411BD9" modified="2018-01-31" version="1">MITTIDNFTKQILGNLKPATKIFLAMARMEETEKPTLLAISNRLDSESTAGITEKSDKIKSKLSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXY3</accession>
    <name>A0A2G4EXY3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016465</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54381">
        <property type="protein sequence ID" value="PHX54381"/>
        <property type="gene ID" value="CP500_016465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="110"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="351"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="425"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="667"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="741"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="824"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="982"/>
            <end position="1133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1133" mass="126930" checksum="54CE2E0E086D521F" modified="2018-01-31" version="1">MQKRLLEWVNQKLDILISENCQGCGLKSEVREAVQETQELFLAIADSMPVPLVISSLADSTILYCNDLCGIFFGIKPEDLIEYEKATTFYSNPADRQKLLEELGRNGRVCEAEVRVKKADGTLFWATVSIRYLTFQSEKVLLSVFCDITERKRAEAAEQELLASIHLRARQQVAVAYLGHLALAETDLLALMDKAGVLIAQTLDVEYCQFLELLPNGLVFMLRSGFGWQAGMVGGATVTASPRSQAGYTLLVGEPIVVADLRVETRFGESPLLHNHEIVSGVTVIVPGNPGVATSNWGETVEAHNFESPVWGILGVHTTQERVFSQDDVYFMEAIANLLAAAIERIRSSERLQMMERAIESTTNGIAIADATIADNPIIYVNPSFERITGYNRDELIGKNCRFLQGKDTNPAAVKKLRKAIEEGKECQVILRNFQKDGTPFWNQLSIAPVYNSRRHLTHFIGVQTDITDRQRAEEELYSQSQALATFSANLKHLHRITTYNYQNFQELVDDYLSAGCLIFGLSIGIVAKVENQSLVIRSAKTDLEYFTPGLELNLADTYCEAVIKFRKTMACCHIKEILETGEYKLYQDWGIESYIGTPIFVNNKIYGTLSFCSRDVRQKNFASQEKEIIELMAQSLSKFLAAHRMEIERQQVEKERSELIVSLQESEERYRSLVELSPEAIAVHSQGKIAYINAAGAKLLGASSPSALIGFPVLHFVHPSYIEIARERIRQVEEENRPIDLAEEQLMRLDGTIIDVEVAGIPAIYQGSAAAQIIIRDVTQRKRVEQKLLHDAFHDALTGLPNRLLFIDRLAQAIHRSQDSPDYKFAVLFLDLDRFKVVNDSLGHLLGDKLLIALAQRLQDCVRLSDTVARLGGDEFTILLDSTQNLGDATLAANRIQKELRVPFNLEGHEVFTTASIGIVFSREEVGVLEGDELNGQQSALYTHPEEFLRDADIAMYRAKALGKARHEVFNLAMHDQTLSLLQLETDLRLAILGQQELGKNKDKSSHFIVNYQPIISIASGAIEGFEALVRWQHPVRGLVPPSTFIPVAEETGLIVPLGAWVLRESCRQLRAWQEMLIKEEGEEGEIGRGGDWERGRLGEGERRLLMPNSRCPIPNSQFPMPHAPCPISDYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXZ0</accession>
    <name>A0A2G4EXZ0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Photosystem I reaction center subunit III</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">PSI-F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_016305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria). This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cellular thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the PsaF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54405">
        <property type="protein sequence ID" value="PHX54405"/>
        <property type="gene ID" value="CP500_016305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
        <property type="term" value="C:photosystem I reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003666">
        <property type="entry name" value="PSI_PsaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036577">
        <property type="entry name" value="PSI_PsaF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34939">
        <property type="entry name" value="PTHR34939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02507">
        <property type="entry name" value="PSI_PsaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81536">
        <property type="entry name" value="SSF81536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013801050" description="Photosystem I reaction center subunit III" evidence="7">
        <location>
            <begin position="24"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="17754" checksum="818F8F8C87C55D62" modified="2018-01-31" version="1">MRRLFAAILVVSLWISFAPVASAYNLVPCKDSPAFKELAENARSTNGDPASAKARFDRYSEALCGPEGYPHLIVDGNLSYAGDFLIPSVLFLYIAGWIGWVGRSYLQAAKKSDSPEEKEIIIDVPMAVSFMLSGFLWPVAALKEITSGEMFAKDDEITVSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYA8</accession>
    <name>A0A2G4EYA8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADPH-protochlorophyllide oxidoreductase</fullName>
            <ecNumber evidence="6">1.3.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_015805</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>chlorophyllide a + NADP(+) = H(+) + NADPH + protochlorophyllide a</text>
            <dbReference type="Rhea" id="RHEA:11132"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:83348"/>
            <dbReference type="ChEBI" id="CHEBI:83350"/>
            <dbReference type="EC" id="1.3.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.33" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54501">
        <property type="protein sequence ID" value="PHX54501"/>
        <property type="gene ID" value="CP500_015805"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00668"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016630">
        <property type="term" value="F:protochlorophyllide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005979">
        <property type="entry name" value="Prochl_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44419">
        <property type="entry name" value="PTHR44419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01289">
        <property type="entry name" value="LPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="321" mass="35662" checksum="4A9E57FD0B764A42" modified="2018-01-31" version="1">MAQNHKSTVIITGASSGVGLYGAKALAAKGWHVVMACRDVRKAGDAAQELDIPQGSYSIMQVDLGDLDSVRRFAREFKASGRPLDALVCNAAIYMPLIKEPLRSPEGFELTMTTNHLGHFLLCNLMMENMKPSYYADARMVILGTVTHNPDELGGKIPPRPDLGKFEGFEAGFKDPVSMVDGKKFEPVKAYKDSKVCNVLTMRELHRRFHESTGITFTSLYPGCVADTPLFRNHYPLFQKLFPLFQKNITGGYVSQELAGERLAMVVADPEYKQSGAYWSWGNRQKKDGASFVQKVSPQARDDEKGDRMWDLSAKLVGLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYC7</accession>
    <name>A0A2G4EYC7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54460">
        <property type="protein sequence ID" value="PHX54460"/>
        <property type="gene ID" value="CP500_016010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="16232" checksum="6F462F985248B2B8" modified="2018-01-31" version="1">MKAEFYYDRYRYTCSLVQVNFTQELKIKNHQGFVLAVKQGSKMGILGKTRQNAKKVDVSKSHFYNVIKAAMNALELEARDELILERERTITEAEEKIQQQDREIRVLNEQLRILKEQVEHLSTEKQQLPMQLIDSVDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYF9</accession>
    <name>A0A2G4EYF9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_015640</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000094">
        <property type="protein sequence ID" value="PHX54526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54526">
        <property type="protein sequence ID" value="PHX54526"/>
        <property type="gene ID" value="CP500_015640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="30044" checksum="5D6CB0AA373C61DB" modified="2018-01-31" version="1">MIWIIGHFLAVGIGVSLGLLGGGGSVLALPVLVYVMGVAPKPAIAMTLIIVGTVSLLGSIPHARRGNLNFKTAVIFGTATMLGAYFGARIATLPFITSAFQMTLFGLSMLIAAGLMIYRTSKSKPVSSQDELDAVEYVKPVCKYCWLWLMTEGIAVGVLTGLVGVGGGFAIVPALVLLGNVPMRQAIGTSLLIIACNSVAGLLGYLGHISLDWNLTVSFTFLAGCGTVIGAYLAQFIPAPQLQKSFGYFLLVVATFVLVQNRDSLQGLKKSSAHQQPQKALSPSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYJ2</accession>
    <name>A0A2G4EYJ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54247">
        <property type="protein sequence ID" value="PHX54247"/>
        <property type="gene ID" value="CP500_017210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="SSF101967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="6736" checksum="AB307DFB7D1B389A" modified="2018-01-31" version="1">MSYWNWALGIGNWALGIGHWELGIGHWELGIGNWALGIGNWALGIGNWELGIGHWLLAQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYL7</accession>
    <name>A0A2G4EYL7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54613">
        <property type="protein sequence ID" value="PHX54613"/>
        <property type="gene ID" value="CP500_015150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="322" mass="36096" checksum="4DB65408844005CA" modified="2018-01-31" version="1">MNTKKIFITGASGCIGHYMTETLIQQTNHELYLLVRNPDKLKFNWKSRPGINILQGDMRDIEQYAELLKTIDVAILAATAWGGTQEVFDVNVAKTLRLIQLLSPQICQQVIYFSTASILGNDNNLLKEAGELGTDYIRSKYECMTKLSELKNVPHITALYPTLVLGGSENKPVSHLSSGIPQVAKWIGLIRWLKADGSFHFIHGADIATVVNYFVEHPADSDETRHFVLGNAPITANEAVEQACAYLNQKIFFRITLSPGLADFFIWLFRIQVAAWDRFCISYRHFTYQNFVNPETIGLPSYCGTIADMLKTSGIPGKDLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYT8</accession>
    <name>A0A2G4EYT8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone deacetylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54638">
        <property type="protein sequence ID" value="PHX54638"/>
        <property type="gene ID" value="CP500_015055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="His_deacetylse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="2">
        <location>
            <begin position="19"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="308" mass="33291" checksum="F54524BB795754D1" modified="2018-01-31" version="1">MLPVIYSDDFLLHKTGMLHPERPERLSAIANALKTAPWADRIEWQLPTPVVEREPELLSAIKKVHAPIYIKQVEHLAAHGGGYLDGDTPISAESYDVALLAASAWLDGVDRVLASGEPAFVLARPPGHHAESDRAMGFCVFSNAAIAASYALKQPGIQRVAILDWDVHHGNGTQSLVENCQQIAYCSLHQSPCYPGTGEADEHGAYDNVLNIPLYPASGIAEYLSAFESQVVPFLSKFQPDLLIVSAGYDATAADPLASMNLAPSDYGTFTGYCLQITRRIAFGLEGGYALKELAESVVATIDRCLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYU9</accession>
    <name>A0A2G4EYU9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54658">
        <property type="protein sequence ID" value="PHX54658"/>
        <property type="gene ID" value="CP500_014970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013848277" evidence="4">
        <location>
            <begin position="34"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="303"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="345"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="387"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="440"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="482"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="524"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="558" mass="58305" checksum="0D1A8FD94CC81806" modified="2018-01-31" version="1">MNYNRTIPAILSASIALSTIALLPFTSPQIALALTADQVKTVAKAVTVRIEGPKGGSGVILEKKGNTYYILTNWHVVDQAGDYRVITPDGKSHSVYYSLIRRSPGMDLAVVPFSSPESYPLAQLANSPATAGKKAIVAGWPISGGSLRQPIFLATEGLLTGRQTAWNGYTLVYNNLVRAGMSGGPVLDDAGRLIAINGIVKLENNSDKIVAAGIEINTFMKWRSTVSLPIVPESPTAKTPSNPVNNSPRKPASAIAFAATNTLKTPSEVVSSISLGFDYFASGNSNGTISVWNLPGGELKSTLRGHTESVNAVAMSADGKILASGSDDKTIKIWNLETGAVVRTLSGHSGAVSSVAVSSDGQFVASGSWDKTIKVWNAKTGELLRTLIGHSGLVNTVTISPIAQIPPLSKGGLGGVLASGSKDGSIRLWNLVNGQVIRTISGKNLSVLSVAFSPDGKNLAAGNSNGTVGLWNAGNGQLIHRLSGHTDGVWSVAFSRDGSTLVSGSWDKSVRLWDVRSGDLRGTLSGHSGYVSAVAISGDGKTIVSAGWLGEIKIWKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZB3</accession>
    <name>A0A2G4EZB3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54854">
        <property type="protein sequence ID" value="PHX54854"/>
        <property type="gene ID" value="CP500_013815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="38"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="198"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="231"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="264"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="297"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="367"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="400"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="433"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="493" mass="51110" checksum="1DE4FD0CAFFE7551" modified="2018-01-31" version="1">MPATKQDALLIQAAKTGNIIHVQALLAKGVNPDAKDSEGTTALMFAAQKGYAEIVRILLKNGANVNQVRRRFGLTALMLAAAHKQADSVRLLLAGGADVNAKNDDGSTALMAASLKGDINVVRLLLTASADVNVCDRDGDSALKIAALSGNESVVKALGDAGAIADNSILFLAVSQGRAAIIRILLNCGADPNIKNADSKTALMQAAIVGNLSVIELLLAAGADVGIFDKDGETALTLAADFGHVDVVLALLGAGADVNVKNRDGGTALMAAAAGGTLPIALILLDAGADINAKDKDDETALNFAVLEGYEDVVELLLNRGASVEQRNRLGDTPLLVAAVHGYTTILSALLQKVNQNNADFLNAKNFGETALTLAVFQGHTETVKVLLEGGVDPNIPGDQGKTALMKACIRGHVAIAKLLVDSGADVNLRDNSDATALMWAAHRGSVDIIKILIDAGADVNHKNLGNYTALMLAEFNSYKEVVKLLKTAGARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZB7</accession>
    <name>A0A2G4EZB7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54851">
        <property type="protein sequence ID" value="PHX54851"/>
        <property type="gene ID" value="CP500_013800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013774238" evidence="1">
        <location>
            <begin position="34"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="27273" checksum="899E8F1D6CE55424" modified="2018-01-31" version="1">MSLWKVKRRFWTLFSLALSCFSLIILTQVYTPAASPPPPDNWPSPRVHSLPPTLANWQDSTNSGDYFDRIKPPKVGHLVWSKFPIQIYVEHPVNTTRSEEWVEAMLGVIREWGVYLPLAVVDSSEVADIRILRQAPPLRPGEKVRSGESVYELYTSQDGDKTILSHRFSVYLNPNQVGKYIAAMARHELGHALGIWGHSLLETDVLFKSQVRNPPPISAKDINTLKRVYEQPTRLGWEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZM3</accession>
    <name>A0A2G4EZM3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA mismatch repair endonuclease MutL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_013390</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54956">
        <property type="protein sequence ID" value="PHX54956"/>
        <property type="gene ID" value="CP500_013390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_mis_repair" evidence="4">
        <location>
            <begin position="128"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="MutL_C" evidence="3">
        <location>
            <begin position="328"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="502" mass="56789" checksum="D626DB379586CC2D" modified="2018-01-31" version="1">MRGGVENNPFSRGEIENARSGWRVVYSAAGEPVEVESIAIAPGTVVTVANLFGNWPVRRGFLAQGKQVRLIELMIQQIALCHPQVNWQLRQGNTTCLHIIPGLTAQQILPQFVRGIRLNDLQYLNVNLPSIPTSKAADSLVKTQLVLSQTNQSYQFPIPHSPFPIPNPPFPIPHSQSLELVMGLPDRCHRRRPDWVKVAVNRRVVRSPELEQTILSAFARTCPRDRYPVCFVHLQISPSAIDWNRHPAKVEIYLHDPSFWQDRVTEVIAKALELNEDVLPQPPIPDRVGQLLKASEQKGTYLVDSSTSQNDSDREAKQHKIGLMELRAIAQVHNTYIVAEHTSGMWLVEQHIAHERILYEQLCNDWQLKSLEKPVILSQLSALQIENLSRLGLEVESFGEQLWAARKVPELLVDRDDCAEALFELSKVADLEAAQVATACRSAIRNGTTLSIVEMQNLLNEWQQTRNPRTCPHGRPIYFALEESTLARIFRRNWVIGKSHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZQ9</accession>
    <name>A0A2G4EZQ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ketose-bisphosphate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_013225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54978">
        <property type="protein sequence ID" value="PHX54978"/>
        <property type="gene ID" value="CP500_013225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="2">
        <location>
            <begin position="207"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="2">
        <location>
            <begin position="228"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="309" mass="33197" checksum="4F5E5DDDEA7A6D86" modified="2018-01-31" version="1">MLTSTSELLETARRNSYAIGAFNVYNLEGVKAVIDAAEALKSPAMLQLHPSALKYGKSPLVALCMEAARQSSVPIAVHLDHSTSEQDIHLALNAGIKSIMADGSPLPYAENLIFTREMTKLSHANGAVVEAEIGRISGTEDGLTIAEKAAKMTDPVEAIEFIQATKVDFLAVTIGNVHGKYFSEPKLDFPRLAKIRASVSVPLVLHGASGLPESMINQSIKLGISKFNVNTEVREAYMDVLKTSSSLSDPDLLEVMAKAIDAMRSVISDKLKLFGSADKAYLHQSPYTETLNVNGIKGKKASASELVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZR9</accession>
    <name>A0A2G4EZR9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4870 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55000">
        <property type="protein sequence ID" value="PHX55000"/>
        <property type="gene ID" value="CP500_013030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019109">
        <property type="entry name" value="DUF4870"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09685">
        <property type="entry name" value="DUF4870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11288" checksum="0CD3067B06316CEB" modified="2018-01-31" version="1">MLSLLCHGAIFLSTLGLSIGVPIGILFVSDDPVVKDNAKEAINFHLNVWLYAIILVPLSFVTFGLAGLIGFAIHWGLTIMAILHVFQSPNESYRYPFIFRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZS6</accession>
    <name>A0A2G4EZS6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9 14">Glutamyl-tRNA reductase</fullName>
            <shortName evidence="9">GluTR</shortName>
            <ecNumber evidence="4 9 14">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hemA</name>
        <name evidence="18" type="ORF">CP500_013090</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 14">
            <text>(S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9 14">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 14">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="4 9 14"/>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55011">
        <property type="protein sequence ID" value="PHX55011"/>
        <property type="gene ID" value="CP500_013090"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000343">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015896">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015895">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018214">
        <property type="entry name" value="GluRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036453">
        <property type="entry name" value="GluRdtase_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036343">
        <property type="entry name" value="GluRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00745">
        <property type="entry name" value="GlutR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000445">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69075">
        <property type="entry name" value="SSF69075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69742">
        <property type="entry name" value="SSF69742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01035">
        <property type="entry name" value="hemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00747">
        <property type="entry name" value="GLUTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="5 9 12" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 9 14" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GlutR_N" evidence="17">
        <location>
            <begin position="6"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="16">
        <location>
            <begin position="171"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="GlutR_dimer" evidence="15">
        <location>
            <begin position="321"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 11">
        <location>
            <begin position="49"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 11">
        <location>
            <begin position="114"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9 11">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 11">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 12">
        <location>
            <begin position="189"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="9 13">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF05201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PHX55011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="430" mass="47667" checksum="5B8EBD89F74F199E" modified="2018-01-31" version="1">MNIAVVGLSHKTAPVEVREKLSIPEQKIEAAIAQLRSYPHIQEVAILSTCNRLEIYIVTTESEPGVREVTQFLSECSKVPLQSLRPHLFILLHEDAVMHLMRVASGLDSLVLGEGQILAQVKQTHKLAQQYKGVGRILERLLKQALTAGKRVRTETSIGTGAVSISSAAAELAQLKGQHLASSRIAIIGAGKMSRLLVQHLLSKGASHISIVNRSMRGAEELASLFKDAQLHLHLLSEMIEVIASSDLVFTSTAATEPLLNKAKLATVLAPDRPLMLVDISVPRNVDSDVKELANVRSFNVDDLKAVVAQNHETRRKMAMEAEGLLEQEVETFDVWLRGLETVPTISCLRDKIELIREQELEKALSRLGSEFSEKHQDVIESLTRGIVNKILHDPMVQLRAQQDIEARRQAMQTLQLLFNLDVDVNQQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZT4</accession>
    <name>A0A2G4EZT4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CP500_012965</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55020">
        <property type="protein sequence ID" value="PHX55020"/>
        <property type="gene ID" value="CP500_012965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="14">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="12">
        <location>
            <begin position="168"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="13">
        <location>
            <begin position="285"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX55020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="403" mass="45878" checksum="D18057539F767327" modified="2018-01-31" version="1">MYQAYKYRIYPTSEQETLLAKSFGCARWFWNYAWNLCQETYKNTGKGLSRGYIQGLLPALKKEYEWLKEPYSQCLQVVALNLSTAYKNFFDKRALLPKFKSKHGRQSISYPQNVKFDGDKINLPKIGLVHCQRHRDFEGDVKTVTVSRNPDGKYFVSVLVDDGKANPELMPVDKAIGIDVGLTHFAITSDGSKFDNPRFFIKHQRNLKRKQQKLSKKKKGSQNRKKARLAVAKVHSKLARCREDFLHKLSRKIVNENQVIAVENLNIKGIVKNHNLAKAISDVGWGMFCTMLKYKAESEGRQYIEIDRWFPSSKTCHVCLNRVDNLSLDVRVWTCKHCGTHHDRDVNAAINIRNEALRIISLGTSESACGGDVSRSGKTSVLLDAIPVESGSQRCIAVSVSVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F025</accession>
    <name>A0A2G4F025_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Guanylate cyclase</fullName>
            <ecNumber evidence="1">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55112">
        <property type="protein sequence ID" value="PHX55112"/>
        <property type="gene ID" value="CP500_012620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011645">
        <property type="entry name" value="HNOB_dom_associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042463">
        <property type="entry name" value="HNOB_dom_associated_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07701">
        <property type="entry name" value="HNOBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="210"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="463" mass="52187" checksum="4E265CA2532757CF" modified="2018-01-31" version="1">MAKPLYTLNPQMFCDVFPFHIGFNHNLEIVQIGEVLQRTHQILLLGEPIDRHFQIHQPAIEFNFLTIQKKLKSLFILESRHNSLRLKGQMVALKEDQVILFICSVWTPDSSLLSKLAVKLKDFAIHDLTPDFLFLQQTSQTAIREVQSLTEELTKQKIQLQASLEVQKELTSLSQIQAQHLKQALSELQETQSQLIQAEKMSSLGLLVAGIAHEINNPVNFIHGNLKYLQEYVENLISLLHLYQKYYPQPSCEIEAEATIIDLIFLENDLPKILNSIKIGSERIRKIVNSLRNFSRHDEAEIKPVDIHSGIDSTLLILQHLLKANGEDPEIQVIKQYGELPLVKCYASAINQVFMNIISNGIDALRDAQKNCADWNKEPIIIIRTLVNDDRNLVVSIADNGLGMEQSVIDKIFDPFFTTKLVGKGTGLGLSISYAIVVEKHGGKLSCVSAIGEGTKFAIEISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F033</accession>
    <name>A0A2G4F033_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-propeller domain-containing protein, methanol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_012445</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000064">
        <property type="protein sequence ID" value="PHX55116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55116">
        <property type="protein sequence ID" value="PHX55116"/>
        <property type="gene ID" value="CP500_012445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="TPM_phosphatase" evidence="5">
        <location>
            <begin position="56"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="240" mass="26213" checksum="FFC756D8052EADB7" modified="2018-01-31" version="1">MIGLLKQLFSWTKYIQPLAATIAIALIASQMAVLPALATGVYEMPMLSAGDRTWVWDKGDVLSRSSESTITSVLDNLETQTGKQVRFVTIHRLDYGETTATFTKQLFEQWFPATEDQTNQILLVLDTVTNSAAIRTGEGVKSLLTDDIAQSVAGETVQVPLREGNKYNEAFTAASDRIATVLSGQPDPGAPEVVDNTQVEGTFKKAEETDRGNATVIVVVLLVLATVIPMVTYFWYQGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F043</accession>
    <name>A0A2G4F043_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55131">
        <property type="protein sequence ID" value="PHX55131"/>
        <property type="gene ID" value="CP500_012150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
        <property type="entry name" value="PTHR31088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="233" mass="26291" checksum="6D2972C8E1339EC3" modified="2018-01-31" version="1">MKKVLYWLMGERAGRTIVGAWNWMWGLPVESGGKVSVAVAEESLRSMQESVQKLATAVSTQVAAYQRAKTKYEEKVREMQTVERQAITAQRNGNEEAARLAMSKVIQTEQILPQLEAQVKQAEQFVNASKDKLNRERTKLEAYKTDMQNMKDMAEINEALGAISKVNNDLSIDSARSQFEQAKNAVQGRNLQQQALAELSENPQERLQAELENMTIDDEVNRRLQMLDGSGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F079</accession>
    <name>A0A2G4F079_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease VapC</fullName>
            <shortName evidence="5">RNase VapC</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vapC</name>
        <name evidence="7" type="ORF">CP500_012280</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55153">
        <property type="protein sequence ID" value="PHX55153"/>
        <property type="gene ID" value="CP500_012280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 5" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="6">
        <location>
            <begin position="3"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="15833" checksum="2433AF20C44E2CC8" modified="2018-01-31" version="1">MNVLFDTSVLVAGLIEDHPSHSQSLSWLERVRSQEIAAFVSTHTIAELYSVLTRIPRQPRINPGLAQRLIVENLSDFNQVVLTAEDYQATVSRMVSLNLPGGGIYDGLIAQAALKAGVDVLLTLNPNDFTRLGDDVRRLVQVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0B0</accession>
    <name>A0A2G4F0B0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55199">
        <property type="protein sequence ID" value="PHX55199"/>
        <property type="gene ID" value="CP500_012120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="23"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="201"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="389" mass="44090" checksum="FD2FB9F515C81A36" modified="2018-01-31" version="1">MKSAVEKLKYALVHEWLTPLATGGSELVVQEILKHVDADVYALIDFESTNPESYLFGREIGTTFLQHFPLARKGVQKYLPFLPIAIEQLDLRQYDIILSSSHAVAKGILSSPGQLHVCYCHTPMRYAWDMTFDYLHSSKAGRGIPGVLTRYLLHRLRQWEVISANRVDYFIANSQHTARRIWRCYRRRAEVIYPPVNIDRFSLMPQKQDFYVTVCRLVSYKNVGAIVQAFNQLGHNLIVIGTGPELDMIRQIAKPNVQILGWQPGEVVEKYMAQAKAFVYAACEDFGIALVEAQACGTPVIAYGVGGALETVLDIRQHPETGTGLFFSSQTAAALVAAVEEFEQLQGKFQPEIGRLHAEEFSPEVFRQRYLGFVERCFEEFHFGDFTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0D5</accession>
    <name>A0A2G4F0D5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase</fullName>
            <ecNumber evidence="9 10">2.8.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA-i(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">miaB</name>
        <name evidence="14" type="ORF">CP500_011985</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37067"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="Rhea" id="RHEA-COMP:10376"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="ChEBI" id="CHEBI:74417"/>
            <dbReference type="EC" id="2.8.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.3" evidence="9 10"/>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55213">
        <property type="protein sequence ID" value="PHX55213"/>
        <property type="gene ID" value="CP500_011985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01864">
        <property type="entry name" value="tRNA_metthiotr_MiaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006463">
        <property type="entry name" value="MiaB_methiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00273">
        <property type="entry name" value="(dimethylallyl)adenosine_tRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="12">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="143"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="11">
        <location>
            <begin position="383"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX55213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="446" mass="50417" checksum="6896D8E31C2CBFB3" modified="2018-01-31" version="1">MTVKPRRYHITTFGCQMNKADSERMAGILENMGFEFSEDPNEASLILYNTCTIRDNAEQRVYSNLGRQAHRKRKEPDLTLIVAGCVAQQEGEALLRRVPELDLVMGPQHANRLEDLLEQVFQGNQVVATEAVEIMEDITKPRRDSKVTAWVNVIYGCNERCTYCVVPNVRGVEQSRTPEAIRAEMEDLGRQGYKEVTLLGQNIDAYGRDLPGTKPDGSNQHTLTDLLYFVHDVPGVDRLRFATSHPRYFTERLIKACAELPQVCEHFHIPFQSGDNDILKAMSRGYTQEKYLRIIDTIRRYMPDASITADAIVGFPGETEAQFEKTLKLIEDVGFDLVNTAAYSPRPGTPAALWENQLSEEVKADRLQQINHVVTTTAMARSQRYFGRVEEVLVEVQNLKDPSQVMGRTRGNRLTFFKGDIAELAGKIVDVKITDIRAFSLTGEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0G8</accession>
    <name>A0A2G4F0G8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trypsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_011735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55246">
        <property type="protein sequence ID" value="PHX55246"/>
        <property type="gene ID" value="CP500_011735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="72"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="381"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="727"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="727"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="863" mass="94282" checksum="972BD4E95996628A" modified="2018-01-31" version="1">MKFVCVIFPQRLLFAGIAFLAAIECGAWLAPHSSRAVVPRGNSPSVSPPILARNDVNCHKGRSPQTPCPIGGLFVQTQNKPSEQLFPLKRTEVKAKIALNISRVQVVQKFENPFSEPLEAVYVFPLPDEAAVDDMEIKIGSRTIKADIKRRDEAIEIYQKARQQGRTAGLLEQERDNIFTQSLANIKPGEKIEVTIRYTESLKFDGGDYEFVFPMVVGPRYISGNSIPPNPPLARGGDLNTTPPNPPLVRGGDLNTTPPLARGGQGGVNTDADRINPPVNPPGTRSGHDIAVSVEIDSGIPISDIRSTSHQITTNRSGNTVSVQLANSDTIPNKDLILRYRVAGENTQATVLAQADKRGGHFAAYLIPALNYKNNEIVPKDVVFLMDTSGSQQGEPLVKSKELMRRFIQGLNPNDTFTIIDFANTAKALSSVPLANTTENRQRAIKYIDKLQADGGTELLNGIRTVMNFPAPATGRLRSIVLITDGYIGGENEVLNFVQQNLKPGNRLYSFGVGGSVNRFLIDRLAEVGRGTSQVIRQDEPSAEAAEKFFRQINNPVLTDIQISWEGMGGKPEIYPIAPPDLFASQPLVLFGRKGDRTNGQLRIRGTLAGGKTYEQILPVNFVPAVSVRQRESNPAAITNTDFGNSAIAQLWARSRIKDLMNQMFGGETKSLVESVTNTALTYRLLSEYTAFVAVSEEVRVEPDGTRRQVQVPVELPQGVSYEGVFESQDTEPTRGGTRSFFPTRSLVAPAPGQRRQQPYRESKSQQQSISRLQIITAEGLDATAIAALTQYLQSLTLPAGVSGETVWELSVQNGLVAKVAIDYSASTLQATDTIETLKRALISWQPPAGLKGTLRLKLRINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Q2</accession>
    <name>A0A2G4F0Q2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55318">
        <property type="protein sequence ID" value="PHX55318"/>
        <property type="gene ID" value="CP500_011480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10378" checksum="2726824E72099E3E" modified="2018-01-31" version="1">MLKTDTTLPLEADLVKNNWEFTEVWIDPNLSPPYLLLLLSDAEGNCRIYDPAEGYKVVFSSQSYDEAQYWLLEDEYEPMEGRLRVSELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Q4</accession>
    <name>A0A2G4F0Q4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome segregation protein SMC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55037">
        <property type="protein sequence ID" value="PHX55037"/>
        <property type="gene ID" value="CP500_012780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="20"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="383" mass="44457" checksum="2240CE06197AD6D1" modified="2018-01-31" version="1">MLREVRIENYKSIHKLKLELGRVTVLIGENGCGKSNILEAIALASAAADDKLDNEFLASRGIRVTEPQLMRSAFEKDNSVRDIKLSLFGQNSQEFSFVLHNDNQPYSQWLNREADKRFILKFRDYLNTFNGDKEELIKSFLDDDQIFINIFNAPINKLIDSVKLHNFLIYSPENYSLRIFEREDQIQPLGIYGEGLFKLLQVLSLEENQEKLTEIKALLRLIDWFKDFEIPHTSSDFEYNLQIADRYLDSDLSYFDQRSSNEGFLFLLFYFTLFISELTPNFFAIDNIDASLNPRLCRRLIEELVELAKKNDKQVILTTHNPAVLDGLDLDDDEQRLFVISRNQLGYTKARRILNPEPLDGQEPVDLSEAFLRGYIGGLPKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F100</accession>
    <name>A0A2G4F100_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_010845</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55431">
        <property type="protein sequence ID" value="PHX55431"/>
        <property type="gene ID" value="CP500_010845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="102"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="341" mass="37056" checksum="37C0F53DD632E649" modified="2018-01-31" version="1">MSRSKALQSYIIVRLLLAPLMLWTITTAVFLLLRATPGDPIDAILGSRAPAAAKAAMRTQLGLDAPLWQQYLKYIQDLFSLNLGTSITTRGQTVWQIIGDNFPATVELAVCSMAIALIVGISIGSLAASRPNTIFDAAGRLFGIITYSLPAFWAGMVLQLIFSVQLGWFPLGTRFPVTLTAPEGYTGLYTIDSLLSANFGQFLISLHYLALPSLTLGILLSGIFERIVRVNLKQTLQADYVEAARARGIPELQILWSHALKNALIPVITVLGLTFAALLGGAILTEVTFSWPGLANRLYEAISLRDYPTVQGIVVFFAGIVVVASIAIDILNAYIDPRIRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F170</accession>
    <name>A0A2G4F170_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage shock protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55510">
        <property type="protein sequence ID" value="PHX55510"/>
        <property type="gene ID" value="CP500_010410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
        <property type="entry name" value="PTHR31088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="234" mass="25876" checksum="9272E76D4720A5E1" modified="2018-01-31" version="1">MGLFDRLWRVIRANINSLVGAAEDPEKILEQATMDMQEDLVQLRQAVAGSIAAQKRTERQYSQAESTATEWYQRAQLALQKGEESLAREALTRKKFYQETATAMKASLGQQNVVVTQLKENMRALESKIYEARSKKDMYIARARSAKASEKLQEMMGNLNTGSGLSAFEKMEEKVMQLEARSEAIAELGGNDLEKKFLALESGGDVDAELAAMKAQLLPGTNMPKLPSGEPPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1D8</accession>
    <name>A0A2G4F1D8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Precorrin-3B C(17)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cobJ</name>
        <name evidence="7" type="ORF">CP500_010080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55569">
        <property type="protein sequence ID" value="PHX55569"/>
        <property type="gene ID" value="CP500_010080"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11646">
        <property type="entry name" value="Precorrin_3B_C17_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021744">
        <property type="entry name" value="CbiG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006363">
        <property type="entry name" value="Cbl_synth_CobJ/CibH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036518">
        <property type="entry name" value="CobE/GbiG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038029">
        <property type="entry name" value="GbiG_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11760">
        <property type="entry name" value="CbiG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159664">
        <property type="entry name" value="SSF159664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159672">
        <property type="entry name" value="SSF159672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01466">
        <property type="entry name" value="cobJ_cbiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CbiG_N" evidence="6">
        <location>
            <begin position="50"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="TP_methylase" evidence="5">
        <location>
            <begin position="342"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="594" mass="64001" checksum="804EEF956F88D967" modified="2018-01-31" version="1">MNRVSPAIVILGQNSLPIAQKISAVFPGSQIYGLTDRTIDVDINFTNFGETLRELFATETPIIAICAAGILIRTLAPLLSDKRAEPPVLAVAEDGSAVVPLLGGLHGVNDLAREIAKALGVEPAITTTGDIRFRTALLSPPQGYYLANPEDAKTFISNLLAGAKVRIEGAANWLSESNLPIAPDAKLMIRITEKAQAPTPDCLVYHPKIATFALAQLSNIDPEIAIVFVQQALEKSGLARDSIAGFFALKHEMGNPALEAIAHFFQAQIRFFNLPELVEFDSAKLIQYNANFDVTAAQIALTAAGKNSQLVEYDRANQLSCAIALAPEPLDVSAIGVSRGQLAIVGTGPGGAPWMSPEVKQILREATDWVGYKFYLDLAGTLREGQKRHDSDNREELDRARFALDLAASGKSVAVVSSGDPGIFAMAAAVFEAIEFDGKPEWDGIDIRVAPGISAMQAAAAAIGAPLGHDFCVISLSDILKPWEVIEGRITAAATADLVIAFYNPISKQRTWQLGRAIEILLQVRSVETPVILGRNLGRIGQSVRVCKLGEFQPEDADMRTLVIIGSSQTRIIPRKYGDVWVYTPRRYSVSEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1F5</accession>
    <name>A0A2G4F1F5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit PurS</fullName>
            <shortName evidence="5">FGAM synthase</shortName>
            <ecNumber evidence="5">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Formylglycinamide ribonucleotide amidotransferase subunit III</fullName>
            <shortName evidence="5">FGAR amidotransferase III</shortName>
            <shortName evidence="5">FGAR-AT III</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purS</name>
        <name evidence="6" type="ORF">CP500_010070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PurS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55568">
        <property type="protein sequence ID" value="PHX55568"/>
        <property type="gene ID" value="CP500_010070"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01926">
        <property type="entry name" value="PurS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003850">
        <property type="entry name" value="PurS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34696">
        <property type="entry name" value="PTHR34696"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02700">
        <property type="entry name" value="PurS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="SSF82697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00302">
        <property type="entry name" value="TIGR00302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="94" mass="10532" checksum="A9A3189056FA438B" modified="2018-01-31" version="1">MTQKYFAQIYVTLRPSVLDPAGTAVQSGLQHMGYDNVERVRIGKYVEVTLTAVGESEAREQLDRICDQLLANPVIENYRVELTEIPLPLTPLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1J6</accession>
    <name>A0A2G4F1J6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
            <shortName evidence="7">EPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">murA</name>
        <name evidence="10" type="ORF">CP500_009895</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55633">
        <property type="protein sequence ID" value="PHX55633"/>
        <property type="gene ID" value="CP500_009895"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008760">
        <property type="term" value="F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019277">
        <property type="term" value="P:UDP-N-acetylgalactosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01555">
        <property type="entry name" value="UdpNAET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00111">
        <property type="entry name" value="MurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005750">
        <property type="entry name" value="UDP_GlcNAc_COvinyl_MurA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01072">
        <property type="entry name" value="murA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="9">
        <location>
            <begin position="31"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate binding" evidence="7">
        <location>
            <begin position="44"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetylglucosamine binding" evidence="7">
        <location>
            <begin position="143"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="2-(S-cysteinyl)pyruvic acid O-phosphothioketal" evidence="7">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="467" mass="49334" checksum="FEBA56C008AB4334" modified="2018-01-31" version="1">MEDKTITPTLNSSNVSASPESDQEVLKIWGHQPLKGHVKISGAKNSALVVMAGAILCPEDCRLRNVPSLVDVRRMGQILSAVGVKIEANGDVLDINASELIDAQAPYELVSQLRASFFIIGPLLARLGFAKVPLPGGCAIGARPVELHVRGLQALGAEVHIEHGTVHAYVKGPNKRLKGAKIYLDYPSVGATETLMMAATLAEGETIIENAAQEPEVADLANFCRAMGAQIQGAGTNTIVISGVPKLHSVDYSIIPDRIEAGTFLLAGAITHSEISLSPVIPDHLTAVIAKLRTIGAKIVTESPDILRIIPGKIHTATDIETLPYPGFPTDMQAPFMALLTLSEGDSIINETVFENRLRHVAELNRMGADIRVKGNVAVVRGVAQLSGAPVVATDLRASAALVLAGLAADGVTTISSLQHLDRGYEQLEVKLQKLGAKLQRVTEGGEAANVEANAEAPVEPVRSGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1J8</accession>
    <name>A0A2G4F1J8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55644">
        <property type="protein sequence ID" value="PHX55644"/>
        <property type="gene ID" value="CP500_009535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="71"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="171" mass="19797" checksum="359FB25F3532086B" modified="2018-01-31" version="1">MGWRFCGLKNFPTLQREEFDCGDEEINNYLKNLVETADEAGFSRTFLMIVEPGEAKICGFYTLSASTIPVKELPDEYKQPLPFPIPAILIGQFAIDRVWQGQGISRQLLADAYRRICLLFEQEIIGFQAIRVDTRNEEAKAFWLKQGFVPFRKTQRSLFLPVRTILRELEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1K9</accession>
    <name>A0A2G4F1K9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55629">
        <property type="protein sequence ID" value="PHX55629"/>
        <property type="gene ID" value="CP500_009875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="51"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="14217" checksum="DC5D04A7D15A089C" modified="2018-01-31" version="1">MAVPFPYNIILGRDTALPCPLEFRLYQLLCQAAHLMAAGKAVSLVPIEQDMTVEEAASLLNVSPEFVVKLLDDGEIPYGKVGNQRRISLVSAIAYKQQRTIKRREILNELAQFSQEEELHETRVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Q3</accession>
    <name>A0A2G4F1Q3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Nuclease SbcCD subunit D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sbcD</name>
        <name evidence="8" type="ORF">CP500_009750</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'-&gt;5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 6">Heterodimer of SbcC and SbcD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SbcD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55679">
        <property type="protein sequence ID" value="PHX55679"/>
        <property type="gene ID" value="CP500_009750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004593">
        <property type="entry name" value="SbcD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00619">
        <property type="entry name" value="sbcd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 6 8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="7">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="412" mass="45416" checksum="C043869C68A5B42B" modified="2018-01-31" version="1">MIKILHLSDIHMGSGFSHGRVNPETGLNTRLEDFANTLSKCMDRAISEPVDLVIFGGDAFPDSTPPPFVKEAFARQFSRLVDAQIPTVLLVGNHDQHSQGQGGASLGIYRTLGIPKFIVGDRLDTYRIETRNGLVQVVTLPWLTRSTLMTKSETENLSMGDVNQLLTEKLTIALEGEIRRLDPKIPTILLAHLMADKASLGAERFLAVGKGFNIPVSMLTRPCFDYVALGHVHKHQNLNASNNPPVVYPGSIERVDFSEEKEDKGFVLVNLEKGKAEWEFCTLPVRVFQTIKVNVAESENPQTELVKAIGKKEIADAVVRLIYQLRSEQLDLIDNAELHSLLGEAHSYTIQPELVSQLARPRLPELNANNSIDPLDALKTYLASREDLKDVAESMLAAAQGLLGGGEEVLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1T1</accession>
    <name>A0A2G4F1T1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heat-shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55724">
        <property type="protein sequence ID" value="PHX55724"/>
        <property type="gene ID" value="CP500_009440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="10"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="145" mass="15826" checksum="1637748F2C1EF8E2" modified="2018-01-31" version="1">MPGKAPLGSSYYGLLGLHPSASPIAIRRSYRELSKLYHPDTTDLPQSVATAKFQQLNNAYATLSNPERRLAYDLKIGYSRMNVIQQPPGFDTPVSQSRAKNFNSAYLDPTDRPLSPGEIFALFILGATLIGCLMLAIAIGLIRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1U5</accession>
    <name>A0A2G4F1U5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_009225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55731">
        <property type="protein sequence ID" value="PHX55731"/>
        <property type="gene ID" value="CP500_009225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="126"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="126"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="242" mass="27465" checksum="D701DE63F88B0E0F" modified="2018-01-31" version="1">MGFVNISIVEGNPHLRSLLGWHLQQVGHWVHQSADINHAREIFFSHQPSLVILDAELPDGDGLVFCRWLQQQQSLILMLSARNSEADIVKGLKSGADDYLTKPFGMQEFMARVEALMRRNRTILPPATLECGLLKIDLVQRRVRLHEAHIELTPQEFSLLYVLAQAGGVPLSRSDLLRRAWPDAIDNPRTIDTHVLSLRKKIEVDPRQPSLIQTVRNVGYRLNLELFNGNEWHSPLPRAVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F223</accession>
    <name>A0A2G4F223_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arsenical-resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">arsB</name>
        <name evidence="5" type="ORF">CP500_008875</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55792">
        <property type="protein sequence ID" value="PHX55792"/>
        <property type="gene ID" value="CP500_008875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015103">
        <property type="term" value="F:inorganic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="PTHR43057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="355" mass="39549" checksum="F4BA45ADA2578C49" modified="2018-01-31" version="1">MKNTTILKQLSFLDRYLTLWIFLAMVIGVTLGVFIPGIEGFINQFQVGTTNIPIAIGLILMMYPPLAKVRYEELGDIFRNPKILGLSLLQNWVIGPILMFVLAITFLHDYPEYMAGLIMIGIAPCIAMVIVWSELAKGDTEYTAGLVAFNSIFQVLFYSIYAWFFLTVLPPLFGLKGSVVNIGIGETAQTVFIYLGIPFLAGFLTRVALVKAKGKRWYHSEFIPKISPLTLISLLFTIVVMFSLKGNLIVQIPRDVVRIAIPLLLYFVLMFLETFYMAWKIKADYAKSASLAFTAASNNFELAIAVTIAVFGINSGAAFAAVIGPLVEVPVLISLVNVSLWFDQRFFRPNTPRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2A8</accession>
    <name>A0A2G4F2A8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="8">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glycyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="8">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glyS</name>
        <name evidence="10" type="ORF">CP500_008025</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55913">
        <property type="protein sequence ID" value="PHX55913"/>
        <property type="gene ID" value="CP500_008025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00255">
        <property type="entry name" value="Gly_tRNA_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015944">
        <property type="entry name" value="Gly-tRNA-synth_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30075">
        <property type="entry name" value="PTHR30075"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02092">
        <property type="entry name" value="tRNA_synt_2f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01045">
        <property type="entry name" value="TRNASYNTHGB"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00211">
        <property type="entry name" value="glyS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="191"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="762" mass="83648" checksum="73B0EB5A308F6D3E" modified="2018-01-31" version="1">MAAFLLELGTEELPASFVCDSVQQWQRLIPANLAEEFLTNDSIHVYATPRRLAVLVTGLPVQQLDREEEVKGPPASSAFKDGKPTKAAEGFAKKQGVEMDALEIRATDKGDFVFVLKKIPGRMSADILTELVPLWISKLEGKRFMRWADGDLKFPRPIRSIVALLDDTVLPITLVSGSDTVKSDRISQGHRVLYTPPTPPLAKGGTSLPTPPLAKGGTSLPTPPLAKGGTSLPTPPLAKGGTGGVSIPQAEGYVECLRAAYVEVDRTQRKTQIQAQVEAAATKQGGYADISDDLLEEVTDLVEWPNAVVGKFDDEFLMLPPEVITTIIVTNQRYFPILKNPKSPELLPYFITISNGDPAKSAIIAAGNERVVRARLADGQFFYKADLAKPLEDYLPKLETVTFQEDLGTVRAKVDRLCKIANLIVNQLQLTAAENLHIARAALLCKADLVTQMVYELPEMQGIMGQKYALASGEPEAVATAIFEHYLPKGAGDNLPETLTGQIVGIADKLDTLVSIFGLGMLPTGSSDPFALRRAANAIVNIIWAAQLPVNLHQLLAESVAEFTAIRPETSPELLSQLYEFFLQRIRTLLQEEKHVDYDLVNAVLGENDPEYTERALRDLLDALERALFLQQIRNDKTLDLIYETVNRSTRLAAQGDLDKIELEPQTVVKPELFQKSSEQAFYDAVVELVPQTQLSKQTRNYQLLVDSLTEIAPTVGNFFDGPESVLVMDADAEIKRNRLSLLGLLRNHARVLADFGAIVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2C8</accession>
    <name>A0A2G4F2C8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55895">
        <property type="protein sequence ID" value="PHX55895"/>
        <property type="gene ID" value="CP500_008345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020912">
        <property type="entry name" value="UPF0295"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11023">
        <property type="entry name" value="DUF2614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="14008" checksum="7689BE6F8FF54E27" modified="2018-01-31" version="1">MNQGTPKISFKLPVISNWLILLGIAWLLASLGLGWIVKSIFILVGFLMLTPVVAFFGLQWWLKRNLVEGKCPVCQYEFTALNQTQCQCANCGEPLKIEQGHFSRLTPPGTIDVTAVEVSSVQQLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2F5</accession>
    <name>A0A2G4F2F5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MAPEG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_008005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55954">
        <property type="protein sequence ID" value="PHX55954"/>
        <property type="gene ID" value="CP500_008005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="SSF161084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="136" mass="15057" checksum="955863AA9D7C4DE6" modified="2018-01-31" version="1">MLTETNATLWPSLVTASALLLYFIVTINVGRARFKYKVSPPQVTGNPDFERVLRVQQNTVEQMILFLPSLWLFAQFISPIWASAIGAVWIIGRILFAWGYYQAAEKRAVGFGISTLATLTLLGGSFTGIIMSLLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2S8</accession>
    <name>A0A2G4F2S8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56083">
        <property type="protein sequence ID" value="PHX56083"/>
        <property type="gene ID" value="CP500_007185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="2">
        <location>
            <begin position="262"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="327" mass="36872" checksum="92310407EFD1BAAC" modified="2018-01-31" version="1">MKFINPKTDYAFKKIFGSDQSQDILISFLNAIVYQGETFITSLEIIDPYAPGRISGLKTTYFDVKALLNNGENVLIEMQAFNVPAFGKRILYNTAKMYVNQLKLGEVYPELRAAIGVAVTDFIMFDEHSKVISQFILKEDELLLNYQHSPLKLVFVELPKFNKTLEELTNVTDKWLYFLRRAPDLEVVPASMSIVPEIEKAFTIADRVNLSLEEVDDLEKREQFERERVGALELSKAEGLAEGLAEGLAEGLTQGLTQGRTEGIQIGQINLIKRQLQRQLGELNQEIEARLSMLSSEQLSALAEAIFDFSSLADLSSWLETNCSNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2V1</accession>
    <name>A0A2G4F2V1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2TM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56080">
        <property type="protein sequence ID" value="PHX56080"/>
        <property type="gene ID" value="CP500_007165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025698">
        <property type="entry name" value="2TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13239">
        <property type="entry name" value="2TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="2TM" evidence="2">
        <location>
            <begin position="17"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="85" mass="9797" checksum="95B3F4FDDBCD89CE" modified="2018-01-31" version="1">MPPRWPRKPDRNDPEYRRLDDRMNFAIHVGLFSASNSGLWFVHNLQKADWPWAVSVTGGWAVLVFVHAIYHFAIADYSPLTKDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2V4</accession>
    <name>A0A2G4F2V4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TIGR03032 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56082">
        <property type="protein sequence ID" value="PHX56082"/>
        <property type="gene ID" value="CP500_007180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017481">
        <property type="entry name" value="CHP03032"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16261">
        <property type="entry name" value="DUF4915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03032">
        <property type="entry name" value="TIGR03032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="109"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4915" evidence="2">
        <location>
            <begin position="233"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="566" mass="63990" checksum="8EE1FE5D48E88E04" modified="2018-01-31" version="1">MSQEISVESLYDRAWAMQKQGDWEAASREYLQVIALQPNYAPAYFQLGNAKLVKQEWPEAIALYRQALNCEQRYSQCWYNLGVALENIREDEEAIAAYQQAVTYNPNYAIAYNSLGVLLTKQENLEAAKICYQKALAIQPDLIPSFGKLANIQYPRESPEAIQIDKAEGIGKEAEGRLKNDLKPDFKSNLVRNLGDEKVEKARDLRDKNMEENQNGKGIAGADSPQDLIGDRDLPSWLTEQQISLACTTYQTSRLMLIGSNPETNTISGYWRIFDRAMGLYCTHNRIYLSSKYQLWQLDNVLESGKFYQGYDKLYIPRIAHTTGDIDIHDIAVDKNNQIIFISTLFNCIATLSDRHSCQPLWKPPFISQYINEDRCHLNGLAMVDGEAKYVTASSQSDVVDGWRDRRKNGGIVIDVASNDIIVTGLSMPHSPRWYRDKLWLLNSGRGEFGYVDLDTGKFNAIAFCPGYVRGLAFWQNWAIVGLSKPRGGDRTFSGLELDELLVAKDAEAQCGIMVIDLTTGAIVHWLRFEGIVTELYDVQVIPQVQKPMALGFQTDEIAQLITLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Z0</accession>
    <name>A0A2G4F2Z0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rfaE2</name>
        <name evidence="7" type="ORF">CP500_006990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-glycero-beta-D-manno-heptose 1-phosphate + H(+) = ADP-D-glycero-beta-D-manno-heptose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59967"/>
            <dbReference type="ChEBI" id="CHEBI:61593"/>
            <dbReference type="EC" id="2.7.7.70"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.70" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56144">
        <property type="protein sequence ID" value="PHX56144"/>
        <property type="gene ID" value="CP500_006990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011914">
        <property type="entry name" value="RfaE_dom_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02199">
        <property type="entry name" value="rfaE_dom_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="6">
        <location>
            <begin position="28"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="164" mass="17538" checksum="4057B02AE54FEC07" modified="2018-01-31" version="1">MISGVYRLRELSAAIASNPAQWRPIVFTNGCFDILHAGHVRYLQSAKALGRSLIVGLNSDASVQAIKPQQPGLPLRPIVPEDERAEVLAALKAVDAVVIFSESTATQLITTLKPDIYVKGGDYQIETLPEAPAVLASGGKISLIDIEVPSSTSAIVQRILQSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F369</accession>
    <name>A0A2G4F369_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Long-chain fatty acid--CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56199">
        <property type="protein sequence ID" value="PHX56199"/>
        <property type="gene ID" value="CP500_006735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="11"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="408"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="494" mass="55155" checksum="56FCB2B2C6C365B0" modified="2018-01-31" version="1">MNLPLINRVLEHKARIAIATNEQTYTYADLLHTSSQIATDLLQDVADLHQQRVAFLIPSGFEYVATLWGIWRAGAIAVPLCVSHPRPELEYVITNSGASMIVAHPNFEALLRPIARSHNLRFILTSETLPTQISPLPEIDITRRALILYTSGTTGKPKGVVTTHQNIQAQVTSLIDAWEWTSSDRILHVLPLHHIHGIVNVLTCALWAGAECEMLSKFDAETVWNRICDGDLTLFMAVPTIYVKLIAAWETATEETQNRRSKSCAKMRLMVSGSAALPVQVLEKWQNISHHFLLERYGMTEIGMALSNPLHGKRESGYVGKPLPGVEVRLVDEKGELVTAETPGEIQVKSPGVFLEYWQNPEATAKTFRDGWFCTGDFAVVDNDNYRILGRMSVDIIKTGGYKVSALEIEEVLRSHPEIHECAVVGVEDIEWGERVCAALVLRSECSLTLGSFRNWAKEQLAVYKVPTRILTVEELPRNAMGKVTKPTIIQLFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F379</accession>
    <name>A0A2G4F379_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56209">
        <property type="protein sequence ID" value="PHX56209"/>
        <property type="gene ID" value="CP500_006790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="12727" checksum="9F99FDC8D894F289" modified="2018-01-31" version="1">MWQKCDRPKKIPAKIGRELINQGASTKLVSGISMPLSGLFRKFAKICGNRQDACSTKDKLSCGTGILPVHQKINCLVEQASCLFIKGLLKAQYSQKKTRPNLVGSYQSIRVHLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F380</accession>
    <name>A0A2G4F380_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PEP-CTERM sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56220">
        <property type="protein sequence ID" value="PHX56220"/>
        <property type="gene ID" value="CP500_006550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013706940" evidence="1">
        <location>
            <begin position="28"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="234" mass="24180" checksum="FCDF540634CCC6DB" modified="2018-01-31" version="1">MNTKLLSALTATAAATALLSASAPAQAFSFGTNGITFQEDTSVNFKFKESHGAYTSSLGIYKVNGFTLANVANLFSETKSSDNDGDNEWKGTLGNTVLGSGSVVFKFLANQVYTLGLSSAGAGMVYSTSGLNLNVASTGSQQAVFGAAAPLWNALGKETTSTFQAAGQFTDGTSSLYNGGTLISFDDRGNVNDTDFQDFTVSAEAVPEPITMTGLALGLGGLISARRRRNKAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F392</accession>
    <name>A0A2G4F392_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmB</name>
        <name evidence="2" type="ORF">CP500_006450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56244">
        <property type="protein sequence ID" value="PHX56244"/>
        <property type="gene ID" value="CP500_006450"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00091">
        <property type="entry name" value="TIGR00091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="213" mass="24737" checksum="9E2C4EA9AF2125D7" modified="2018-01-31" version="1">MARVRVREHVNPLSIRYQASASPPDWTKIYTDLNLPLHLDIGCGRGRFLWHMAQIQTDWNFLGLEIREPLVEEANVWRDEKGLTNLHYLFCNANSSLKPILETLPPGILQRVSIQFPDPWFKNKHHKRRVVQPELVNDLATYLAIGGEVFIQSDIEEVEREMCDRFSSHASFQRQNDGEWLAENPLPVATEREIGRLKRGEPVYRALYHKSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3D9</accession>
    <name>A0A2G4F3D9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="8">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purC</name>
        <name evidence="10" type="ORF">CP500_006620</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56231">
        <property type="protein sequence ID" value="PHX56231"/>
        <property type="gene ID" value="CP500_006620"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01415">
        <property type="entry name" value="SAICAR_synt_PurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033934">
        <property type="entry name" value="SAICAR_synt_PurC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01057">
        <property type="entry name" value="SAICAR_SYNTHETASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR_synt" evidence="9">
        <location>
            <begin position="6"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="242" mass="27333" checksum="D92DBA7F47B2E4BD" modified="2018-01-31" version="1">MSPDRKLYEGKAKILYSTEDSEILLTHFKDDATAFNAQKRGSIIGKGEINNAISAHLFRMLAAKGIPTHFIDTPAPNQMRVCRVQILPLEVVVRNIAAGSLCKQTGIVLGTVLDRPLVEFYYKNDDLGDPLLTRDRLLLMQLASAEQVDQLDRAAREINEILKEFFSQCGITLVDFKLEFGIDQHQNLILADEISPDTCRLWDNAETDPDARVMDKDRFRRDLGSVESAYQQVLQRVLAQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3G8</accession>
    <name>A0A2G4F3G8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-1-phosphate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rfbF</name>
        <name evidence="2" type="ORF">CP500_005930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56323">
        <property type="protein sequence ID" value="PHX56323"/>
        <property type="gene ID" value="CP500_005930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047343">
        <property type="term" value="F:glucose-1-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02524">
        <property type="entry name" value="G1P_cytidylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013446">
        <property type="entry name" value="G1P_cyt_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02623">
        <property type="entry name" value="G1P_cyt_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="258" mass="30039" checksum="3E83AD56037D58EC" modified="2018-01-31" version="1">MQVVILAGGLGTRLREETEFRPKPLVDVGGYPILWHIMKIYAHYNFQDFIVCLGYRGNMIKEYFLNYEAMNNDFTICLGRKNSITYQEEYREQKFNVTLAETGLASMTGGRVKRIEKYIDRDNFMVTYGDGVADVNVAELLAFHKAHGKLATVTTFRPISRFGILDVDSQGRVLEFSEKPQIDGWISVGYMVFNRRVFEYLGGDDCILEQEPMQRLAADGELMAYRHNGFFFAMDTFREYKYLNELWDRGEAPWKVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3G9</accession>
    <name>A0A2G4F3G9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MazF family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56288">
        <property type="protein sequence ID" value="PHX56288"/>
        <property type="gene ID" value="CP500_006275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="11875" checksum="399942D805B165E9" modified="2018-01-31" version="1">MPSYSKNDIILVRYPFSDLSSSKVRPAIVVSAPHVSQDIMIVPLTSKTASLLEGEFILAEWSTAGLNVATAVKRGLYTVHESLVVITIGQLADSDAERLEQSLRGWLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3L9</accession>
    <name>A0A2G4F3L9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56373">
        <property type="protein sequence ID" value="PHX56373"/>
        <property type="gene ID" value="CP500_005890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="2">
        <location>
            <begin position="64"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="350" mass="40713" checksum="EF53CC8ADA54013F" modified="2018-01-31" version="1">MTASIEKPLNLTSASDTSNLRLKDILKTLPREVFVKNPRKAWTKVIINVLLVAVGYWGIAVSPWFLLPLMWIFTGTGLTGFFVIGHDCGHRSFANRRWVNDLVGHLAFLPLIYPFHAWRHGHNYHHKHTNKIGEDNAWQPMTAEDYAAAPKVLQIAYSLIFGRLWWVGSIAHWAKVHFMWWRFKGKQQQEQVRFSVLVVLIGAAIGFPILIATTGIWGFVKFWLLPWMVYHFWMSTFTIVHHTAPDISFKEPSEWNEAEAQLSGTVHCDYPRWVEFLCHDINVHIPHHLSTAIPWYNLRLAHSSLKENWQDHLYETEFSWALMKRIADNCHLYDPSGGYLTLEEFEAQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3U0</accession>
    <name>A0A2G4F3U0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56147">
        <property type="protein sequence ID" value="PHX56147"/>
        <property type="gene ID" value="CP500_007095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="593" mass="67695" checksum="D685A1D689F722B1" modified="2018-01-31" version="1">MAIKVRELLLDSSRRLKAGQCARSRVLTRFTEDINFPLIVNACSDYLNRIPVLSEGSVQEIQRPAKAVTLSILVISKTVENINQLLRAIRIENLKEPYEVLCSWNGSDSDIQNIQCPDGIYFHIVEQRPYHFARNNNALAQIACGEFLLFINDDVIPDKGAIERSLEAIRNPGVGIVGINLRYRDELLQHGGVFFREDGTSYHRLKRQIRWDDPQVATDIFVPAVTGAFIMMRREEFEAIQFDETFNVCGEDIALNLSYREKFNREILYLGQATALHVENATRRTTGETLTPPEDMTRIVSYSRRLLDGRPITEVRYPRVRIVTEKPGWIMHRMAEEIQKHIGAENVRINEDWEEADIHYYINYGYFRDQPKNGIKVANFTHYDPQNLAEKFVQVAKEVDHCIAISKATADILADFGIPTAKTTVIVIGADKCFQPLLTLGVVGRTYAAGRKGEDIVKALLEDQELMRRVRIVATNDSWGAPVWQFDDRADFYRAIDYLLVPSRLEGGPVPFMEALACGTMSIAPEIGVIPQFSHISYPVGDINALKKLIHKLADQHFSEKHKLSSEMRGFNWGAWAVEHEKLFRSLIARRFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4F4</accession>
    <name>A0A2G4F4F4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system ParD family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56663">
        <property type="protein sequence ID" value="PHX56663"/>
        <property type="gene ID" value="CP500_004410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022789">
        <property type="entry name" value="ParD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36582">
        <property type="entry name" value="PTHR36582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03693">
        <property type="entry name" value="ParD_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02606">
        <property type="entry name" value="antidote_CC2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="90" mass="10411" checksum="4A08D34BDF66EDC6" modified="2018-01-31" version="1">MKSINISLPEAMRSYVEERVAKGGYGTLSEYFRELVRLDRKRKAQECLENLLLEGLESGEATEMTDSDWEDVRQAVRVRLSQRSRTNEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4F8</accession>
    <name>A0A2G4F4F8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56367">
        <property type="protein sequence ID" value="PHX56367"/>
        <property type="gene ID" value="CP500_005860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="12852" checksum="FDA70FB0E55D14E5" modified="2018-01-31" version="1">MDRLDEYRQFIQNILDGYAQIPYQYGEIKSSVIVDREQNNFLLMHEGWEGAKRIHDCIVHVEIMDGKIWIQQDGIETGITAELVELGVPKDLIVLGFHPYHVRQHTGYAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4I8</accession>
    <name>A0A2G4F4I8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56666">
        <property type="protein sequence ID" value="PHX56666"/>
        <property type="gene ID" value="CP500_004000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="133" mass="14976" checksum="F8E0748064824320" modified="2018-01-31" version="1">MTQLNVTVTNDRFPELIARVEDTGERIVIEQEGRAIAAIITYANLKRLEALETDLINKAKLEEYEWLKAAICNRAFDSLRDSAEDIYTLADGLPFQDSEWIKTVAIGPNFGSILDPENELQTQTKETGFSPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Q1</accession>
    <name>A0A2G4F4Q1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56718">
        <property type="protein sequence ID" value="PHX56718"/>
        <property type="gene ID" value="CP500_003650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018538">
        <property type="entry name" value="HerA_barrel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="PTHR42957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09378">
        <property type="entry name" value="HAS-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAS-barrel" evidence="3">
        <location>
            <begin position="8"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="DUF87" evidence="2">
        <location>
            <begin position="174"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="578" mass="64693" checksum="F9560F6DEB2E6787" modified="2018-01-31" version="1">MTTDKPLGSVIQGSLSKGLEVRLHADVSVEDMRVGKFLVVRGVRSHFFCMLTDVSLGTSSDRILSNPPNPNDDFLIAVLAGSSTYGTIQLAPMLMLTAEREKQQAIFNPNSSTTNGKKSGTQNLGSLQPQSSADMELLPVKTIPSHFSQVFDAKETDFRAVFGWEDDPYRRNFAIGKPIDMDVPVCLDLDRFVERSNGIFGKSGTGKSFLARLLLSGIIRKQAAVNLIFDMHSEYGWEAVSEGKQFSTVKGLRQLFPSQIQIYTLDPESTKRRGVRDAQELYLSFDQIEVEDISLVQRELNLSEASIENAIILRNELGTGWINKLLEMSNEDISMFCDEKRGNKSSIMALQRKLERLNDLKYIRKRCPKNYVSEVLQCLDGGKNVVIEFGSHSDLLSYMLAANVITRRIHQAYVRKAEKFLQSKNPCDRPQPLVITIEEAHRFLDPAIVRSTIFGTIAREMRKYFVTLLIVDQRPSGIDGEVMSQVGTRITALLNDDKDIDAIFTGVSGGQSLRSVLAKLDSKQQALVLGHAVPMPVVVQTRPYDEQFYREIGDIDWQEMPDAEVFAEAEAAKMDLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Q4</accession>
    <name>A0A2G4F4Q4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56752">
        <property type="protein sequence ID" value="PHX56752"/>
        <property type="gene ID" value="CP500_003840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="124" mass="13519" checksum="902B5BC55BC2B9EE" modified="2018-01-31" version="1">MSENSNIKFTIAFNDPDLDSQELEEQAQRLMAELKQMDEVAVDRVLDPNPPEGNKAIGGMLVGLLTAEVTLANAKKLMGFLGDRLGGKPIELSVEANGKKLTVKAHSREELEAAIKLAQDFIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Q6</accession>
    <name>A0A2G4F4Q6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56477">
        <property type="protein sequence ID" value="PHX56477"/>
        <property type="gene ID" value="CP500_005145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="1">
        <location>
            <begin position="5"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="270" mass="29588" checksum="7056077A6A69787F" modified="2018-01-31" version="1">MVTVEILAIGNELLIGDVLDTNTNWIIKKITGIGGQVNRSVILRDNLDAIATEIQSALQRKTEVIFTIGGMGPTVDDMTLAAIAQSINQPLEANKEAIAFVNQKYQEFAKKGYVDDSKMTPPREKMGILPMGSIPIDNPVGAAPAVISKVKESTIISLPGVPRELKEIFENTLQPILKEKFGEIFFLEKVAIVDSKDESVIAPILNAVSQKNPQVYIKSRAKNFDIDAKFKVTISCCSSFKKEVIQAINKAIQDLRQELGNAGISLDYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Y6</accession>
    <name>A0A2G4F4Y6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56557">
        <property type="protein sequence ID" value="PHX56557"/>
        <property type="gene ID" value="CP500_004730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="14429" checksum="12D7891B2764006C" modified="2018-01-31" version="1">MATKSFQELRVYKLSERLADEIWTTVNTWEPFAKNTIGQQIVRSADSIGANIAEGVGRGSYQDNRRFVKIARGSLYETQHWLRRAYTRNLLTVEQVNTFTTIINDLAPQLNSYLQSIGSSPKNHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5B0</accession>
    <name>A0A2G4F5B0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2442 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56993">
        <property type="protein sequence ID" value="PHX56993"/>
        <property type="gene ID" value="CP500_002595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018841">
        <property type="entry name" value="DUF2442"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036782">
        <property type="entry name" value="NE0471-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10387">
        <property type="entry name" value="DUF2442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143880">
        <property type="entry name" value="SSF143880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="98" mass="11360" checksum="F2408E929DB9A9B0" modified="2018-01-31" version="1">MKPERIVSAKAMDDRTLMVKFTNLEFKKYDISKLLKNPMFATLSNPGFFRNFTIEPGGYALVWNDEIDISEYELSKNGVSCTDEEIERHIESIHQVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5B4</accession>
    <name>A0A2G4F5B4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56962">
        <property type="protein sequence ID" value="PHX56962"/>
        <property type="gene ID" value="CP500_002430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="15623" checksum="98522D58EA1B33BC" modified="2018-01-31" version="1">MTQSFSNNVPSPRFSNQSPGTLDDELRSADELGIRPVKVGESGFDDIINEGTVKWAVTTELELLVIPKFLDVSNEIYHTVITLGEPVLAAGEAEIVGSNGSYILLTISNHSGHFQPTSESLELGITAFRQQGVDTNNADIEYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5J8</accession>
    <name>A0A2G4F5J8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56981">
        <property type="protein sequence ID" value="PHX56981"/>
        <property type="gene ID" value="CP500_002530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013660033" description="Peptidase S1 domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="27"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="367" mass="38291" checksum="22FDBBBD3753222B" modified="2018-01-31" version="1">MLTVKTQNLITSTVTAFVAAAGLCGSAIAGTIRHDRSDAQYTNFANQNQFASVGRLDMRFANNTFTGCSGTLISSNWVLTAAHCFENGQQSLAGAGFTIGGRSYSINLGLQNGGWASSNRNLGAGADIGLYRLSSSISNINPATLYSGNNEDLQVGSYVGFGNTGNGLSGANTTSFGTKRAGQNTIGLGSRLGYSNGILVSDFDDPRSVNPSDPLTRPLNLEYQLAKGDSGGALFIGGLLAGVNSFINSFDGNTDADYGDISATTRVSSHSNWIQNVIRGMAGTGVLNSLPRTSSNFGPTTLAQVVLDESETIGDLSQPLELVQDTWDNSESIAEPVPEPTTVVGGLISLGGLIVARRRRNLAQKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5L3</accession>
    <name>A0A2G4F5L3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4058 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57074">
        <property type="protein sequence ID" value="PHX57074"/>
        <property type="gene ID" value="CP500_002000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025132">
        <property type="entry name" value="DUF4058"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13267">
        <property type="entry name" value="DUF4058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="260" mass="29044" checksum="5E7C279BF355A6E4" modified="2018-01-31" version="1">MPSPFPGMNPYLEQPEFWSEVHSRAIVAIAIAIEPELNPNYRVAVEKRIYLSASSELVGIPDISLVSKQSNPNPSVSGTATLTRSKPIPVQLPLPETVKESYLEIREMPSDRVITVIEVLSPKNKTAGEGRNAYETKRQQVLGSRTNLVEIDLLRSGKPMPILGVTDRTDYRILVSRGSQLPQAELYAFSVRDVMPCLRVPLQPSDAEPELDLQAILMSVYNQARFDLAIDYCQEPRPPLKAADREWADNLLRQLGVRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5L9</accession>
    <name>A0A2G4F5L9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57038">
        <property type="protein sequence ID" value="PHX57038"/>
        <property type="gene ID" value="CP500_002295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="96"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="12"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="369" mass="42151" checksum="1C7B6B11678842AE" modified="2018-01-31" version="1">MKSEQIDALAMIKHLEKENRILRKKLERSETTCLELEQTNQKKEYLLRQIINELENSQKELKEKRQLEQTLIELKRTQTQLIHAEKMSSLGQLVAGVAHEINNPVSFIHGNLRYLEEYSQNLLNIVQLYQQHYPNPNPEIQEESDAIDLDFLQKDLLKILSSMKLGTDRICNIVLSLRIFSRMDEAEFKPVDIHEGIDSTLLILQHRLKNKPEYSEIQVIRNYDHLPLVECYGGQLNQVFMNILANAIDAVDEVNEKRTVQERKENSSQITISTSVIDSEWVQIAIADTGLGIPESIQKQIFNPFFTTKPIGKGTGMGMAISHQIITEKHGGKLMCFSTPGTGAEFVIRIPIQKQIESETNSSVKSLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5P6</accession>
    <name>A0A2G4F5P6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57104">
        <property type="protein sequence ID" value="PHX57104"/>
        <property type="gene ID" value="CP500_001485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="63"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="278"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="356" mass="38634" checksum="17F0065A8B2C6877" modified="2018-01-31" version="1">MGNKKINKSELMLQVHAKEMFSDYITAVTWSPDGKILAVSSAAGEVMLGNVETLNQLSLQPLQTATGNSIDCLAFSSDSQLLAAGGQDGKVRIWLVNSGELIADLGNNRVWVDKLAWNPNCNQLAFSMGRCVQVWNADDNTVEVILNFDSSSVLDLAWHPVDKYLAISGYQGVKVWNGEDWDEDPHVLSVPSATGAISWSPSGKYLACGNMDNTLIVNEWGNYEPWVMQGFPGKVRELAWSDQTNSLGVPLLAASSSQGISVWERDADESVGWEGWALEVHENVVNAIAFQPNTFLLASASADGQLCLWEEAEELLQILEGAERGFSCLSWHPQGQFLGAGGCGGELLVWRQGIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Q3</accession>
    <name>A0A2G4F5Q3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hybrid sensor histidine kinase/response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_001995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57102">
        <property type="protein sequence ID" value="PHX57102"/>
        <property type="gene ID" value="CP500_001995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="15"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="201"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="133"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="50880" checksum="85CDFD69F2DEBFC7" modified="2018-01-31" version="1">MALKNSISTLFDNSIILIIDDMPINLKVLSSVLADAGFEVAIATSGQDALQQLEHTPVSLILLDVMMPGIDGFETCRRIKANPKTHNIPVIFITALSEAIDKVQGFDLGAVDYITKPFQQGEVLARVRTHLKLNQLSRTLELKNTELQQLTEELEQRVIERTHELFTQKRNLEQALVELQQAQIQLVKSEKMSALGNLVAGIAHEMNNPLGFISASLKQAQPTISELIEHLKLYQESLPNPSEEILDHAEQIDLDYTLEDLPKVIDSMGMACDRLKCISTSLRTFSRADTDHPVACNIHDGIDSTIMILKHRLKANENRPEIPVIKDYGSLPQVECYAGQLNQVFMNVLANAIDALDESNQGMSYKDIDNKIMIKTELSIDQKQVIIRIKDNGFGMRQQVRDKIFDELFTTKGVGKGTGLGLAIAHQIVVEKHGGAIDVNSVLGKGSEFAIVLPVCSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5S7</accession>
    <name>A0A2G4F5S7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transglutaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57098">
        <property type="protein sequence ID" value="PHX57098"/>
        <property type="gene ID" value="CP500_001900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="1">
        <location>
            <begin position="406"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="542" mass="61379" checksum="5D6A07C5D1B77CB3" modified="2018-01-31" version="1">MGVLALHGIAFLGNRLFAVDRAEGLLLEIDRESDNTTVLNPCQTAKFLGATGLAIWEDTIWFARGEDICCCRGAIRDGEIVELKPEHFVSLTYPADGIAVWESTLYVTCQRQGYILVFDCKTGREITRFYVPGIGVENITIRNEELWVCDKTEQTVYCLERANGDIKFSVLTPFENPSGLAFHKDSETGEEILYVAYAGDELYIRDDPNSEDPFQLTKRDRTFIQPLSFHYNEAESYALSNGFLMEMSYVEELSPLDEVEIDNLEWRIALPSETHRQKVRQITPIGMPFTEEIQQGERVAVFKFDRLQAGERRIFGWKALLEVRAIKYQLSPREVEKIPKLSPEFEAKYLVDNDNLAMDTEIVRSAATAAIGSETNILRKLLSIRNFVYDQLSYGIRPHIDTPDIVLRRGVGSCGEYVGVLLALARLNGIACRTIGRYKCPAFADRKGVPLEPDFNHVWLEFYIPGFGWVPMESNPDDIQEKGPYPLRFFMGLAWYHVEIGKGIRFQSLTSGGLPLNKENVSVGTLAINHVRFTILSELPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6N0</accession>
    <name>A0A2G4F6N0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_000800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57351">
        <property type="protein sequence ID" value="PHX57351"/>
        <property type="gene ID" value="CP500_000800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007791">
        <property type="entry name" value="DjlA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05099">
        <property type="entry name" value="TerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="651"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="TerB" evidence="4">
        <location>
            <begin position="18"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="3">
        <location>
            <begin position="286"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="204"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="518"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="838" mass="94553" checksum="1DE6A7F985B991AC" modified="2018-01-31" version="1">MSDIISKTTEHLDHPFLLVTHMVCADQQIHSEESKALRELAMQISASQRTLAEMEKILAQDENHLSVEDLARKVSPGEQSEAMSQMLAIAYVDGFCSALEREMAEQVARIWNWPAGEVQRQLAEVGAFSDTRFIGEHNQQQKPSIGARFLKGADSLLSRALVDNVAKLTGSEQKVEQIRREILLTGPEYDEAIRQCAVIADEDYKFAELALESADKALSKLAKNIQVAIEDIKYKTGGKDQATTAKEVAKQLEDTKNSLTAEIIKEIESVRESLRAKERALNHFSIAFMGRTKAGKSTLHAIITDGGWDAIGVGKQRTTRLNQVCEWKNIRIIDTPGIGAPGGQSDEEIAKSIIDESDVICYVVTNDSIQESEFGFLRLLKEKAKPLIILLNVKNNLRDSRRLEHFLKNPDKLFEMDGQSGLGGHIERIRRYAQEHYANDYFDIVPVMLLAAQLSREPEHEKKKKELFEASRMQDFLDSIRVSLVNHGAIRRSQTLLGSTVGAINNPYQWVNQQALVYEKLAQTLKNKREAIQNDIQKAAKDAREYLRQQIERIFQDAINAIPSFAEDHWNSNEIAMKLGWEQKLKALRFEKRLKIAYEETSKKFNKEVQEVLEEIGNELQLISQLGSSDFSFTEQDSNNFRDFVRIGGGLLGIAGTIIALFVAPPVGIAIAIGTGVFSMMTGMFKSKDEKRREAVINISTSLETQLNTHRQRTLQQAKGDFGKYSDSVTTNINIYFEELIAGLDAIATHLERAKKKLSGIENYLNRAYAKRIIDWCAEKYETMTDECINQIIATVERDLGRNMKIVTKSKVQQLKSLEDIKHILQEDISFSDLKSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Q2</accession>
    <name>A0A2G4F6Q2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF5009 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57452">
        <property type="protein sequence ID" value="PHX57452"/>
        <property type="gene ID" value="CP500_000285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032176">
        <property type="entry name" value="DUF5009"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16401">
        <property type="entry name" value="DUF5009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5009" evidence="2">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="452" mass="51966" checksum="1D91590B6A6CE8EE" modified="2018-01-31" version="1">MVLSGTIARKTLPAWMYHAQEAPPIHAFNPKLAGLTWVDLVFPFFLFAMGAAIPLALSRRITKGWDIKTIILSILQRGFLLGSFAIFLQHIRPTVIDPNEPGSHKWWLGLCGFLILFLMFVRWPTKKLPWLRIGTTIAAWSAGILFVSRIKYPNGIGFDFNRSDIILVVLANMAVFGSIIWLFTRSNTWLRVGFLGFIFAMRLASRTDGWIKLVWFYSPAPGIFQFDYFKYLFIVIPGTIVGDLLYRWIEYRSPEDQIYANWKSPRYFSIFILMFAINLVLLVGLQARLVWQTSLVTLVLCLCGLVLLKNPGNITENLLNRLYKWGFYWLVLGLLFEPYEGGIKKDSATMSYFFVTTGMAIFMLIGLTVIIDVFQKRWWLQLFIDNGVNPMIGYVGFANIVWPILVLNQWEPVIIEMTSTDPFMGFLRGFGYTAIVALIVVVFTRFKLFLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUH7</accession>
    <name>A0A2G4EUH7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Threonine-phosphate decarboxylase</fullName>
            <ecNumber evidence="5">4.1.1.81</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">L-threonine-O-3-phosphate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_022745</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + O-phospho-L-threonine = (R)-1-aminopropan-2-yl phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:11492"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58563"/>
            <dbReference type="ChEBI" id="CHEBI:58675"/>
            <dbReference type="EC" id="4.1.1.81"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.81" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000244">
        <property type="protein sequence ID" value="PHX53202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53202">
        <property type="protein sequence ID" value="PHX53202"/>
        <property type="gene ID" value="CP500_022745"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005860">
        <property type="entry name" value="CobD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01140">
        <property type="entry name" value="L_thr_O3P_dcar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="11">
        <location>
            <begin position="25"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="383" mass="41869" checksum="6184C6A20C3BCE6F" modified="2018-01-31" version="1">MTRPVHGGNLAWAATLAGCPASAILDFSASISPLGPPQSALDAIQSHLSSLTAYPDPDYGELRAALGEALNVDPDWILPGNGSAELLTWAAWDLSKLEATYLVTPAFGDYWRALNAFGAKVLECPLDLQSCTIVKNGQDAHSTRDKFSCGTGILPVPKQVIENGATSFRGLLLNNPHNPTGLLFSREAIRPYLQQFPLVVVDEAFMDFLPPEKQESLIDAVAEFPNLVILRSLTKFYSLPGLRLGCAIAHPDRLRRWQLQRDPWPVNALAALAAAAVVRDAVFERQTWDWLPVARQELFEGLASLPGLRPFPGAANFLLVESSVSVALIQKGLLEHHRILIRDCLSFPELGDRFFRVAVRDRADNLRLISALKEVIGPLTVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUK5</accession>
    <name>A0A2G4EUK5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP--corrinoid adenosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_023085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000263">
        <property type="protein sequence ID" value="PHX53146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53146">
        <property type="protein sequence ID" value="PHX53146"/>
        <property type="gene ID" value="CP500_023085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="377" mass="41379" checksum="77FF9DFEC4E20AE9" modified="2018-01-31" version="1">MVRNGIGIRTASSRSERAAGQIHVYDGASKGKSQAALGVVLRSIGLGINSDSPTRVLLLRFLKGPGRSYDEDGAIEALQRAFPHLIDQVRTGRAEYFGPEAITRFDRTEAQRGWDIAKGAIASELYSVVVLDELNPVLDLGLLPVDEVVQTLKNKPEYLEVIATGRATPQALLDIADLHSEMKPHYHPAAAEHNITGIEIYTGAGKGKSTSALGKALQAIGRGISLDQSHRVLIVQWLKGGTGYTEDAAIAALRQSYPQLVDHQRCGRDAIVWRGQQQEVDCTEAERGWEIAKAAIASGWYKTIILDELNPTVDLELLLVEPIVEALLRKPRDTEIIITGRCHKPHAYFDLASVHSEVYCHKHYGDRGVELKRGVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUK6</accession>
    <name>A0A2G4EUK6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000240">
        <property type="protein sequence ID" value="PHX53215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53215">
        <property type="protein sequence ID" value="PHX53215"/>
        <property type="gene ID" value="CP500_022680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="18214" checksum="C1145A5D7885BD6B" modified="2018-01-31" version="1">MANNKQSVKETDANIDPISGETGAHPVGTGIGAAGAGAAGAAIGGAIGGPVGAVVGAVVGAFSGGLAGKSVAEAIDPTVENAYWQNNYSDRPYVETDTSYEDYQPAYRTGYEGYSRYSGTGKSFNELEDDLERDYEANRGKSNMNWEKAKHATRDAWDRVERALPGDIDKDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUT7</accession>
    <name>A0A2G4EUT7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4336 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000221">
        <property type="protein sequence ID" value="PHX53294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53294">
        <property type="protein sequence ID" value="PHX53294"/>
        <property type="gene ID" value="CP500_022270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="PTHR33835"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="402" mass="45979" checksum="01BB00B8EBD1FBA4" modified="2018-01-31" version="1">MTEGEGISRSEQINSRDFSWPFWPIVPIYPYGKRRTIRKEIVKDTIWTFDQLQGIFYVIVPIRMTVIKLEPEGLLVYAPVAPTPECIRLVNELVAEHGEVKYILLTTISGIEHKVFVGPFARCFPSAQVFVAPQHWSFPLNLPLSWLGFPTKRTFVLSLDSSETPFADQFDLAILGPIDLRLGWFAEVALFHKRSRTLMVTDSVVSISDHPPAIVQFDSYPLLFHAKDSASDVVADTQENRRKGWQRIALFAMYFRPSVLEVRSWMSVLDNGFKAPERSKKAYFGLFPFQWKPGWKRSFEALRGGGRLFVAPILQTLILNRQPQETLDWANRVASWDFERIIPCHFDGAIATNPREFRQAFSFLEKHSDVTLLPEADFKLLRDIDAGLNKIGIVPPAKDKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUV8</accession>
    <name>A0A2G4EUV8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Photosystem II protein Y</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">psbY</name>
        <name evidence="8" type="ORF">CP500_022020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Manganese-binding polypeptide with L-arginine metabolizing enzyme activity. Component of the core of photosystem II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cellular thylakoid membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PsbY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53332">
        <property type="protein sequence ID" value="PHX53332"/>
        <property type="gene ID" value="CP500_022020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00717">
        <property type="entry name" value="PSII_PsbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009388">
        <property type="entry name" value="PSII_PsbY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06298">
        <property type="entry name" value="PsbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="41" mass="4469" checksum="26172A61877254A6" modified="2018-01-31" version="1">MDFDFRILIVLLPVLLAGGWALFNVGAAALTQVQKLLNKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUY0</accession>
    <name>A0A2G4EUY0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53352">
        <property type="protein sequence ID" value="PHX53352"/>
        <property type="gene ID" value="CP500_021950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045784">
        <property type="entry name" value="Radical_SAM_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19864">
        <property type="entry name" value="Radical_SAM_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="220"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="539" mass="60509" checksum="DAA74DF9B7EBE2D6" modified="2018-01-31" version="1">MTPNPFVEERLLFAPATPDVDAIPTIFAFPNEYTVGITSLGYQIVWATLAVRSDIEVGRLFTDVHEQLPRHPELLGFSFSWELDYVNILNLLESLEFPIWASQRTDSHPIVFGGGPVFTANPEPFADFFDVILLGDGENLIDNFINTFKEVRTADRQTKLRHLAQVPGVYVPSLYEVTYLDATEGIKSIQPIDAAIPSMVEKQTYRGNTLSASTVVTEKAAWENIYMVEVVRSCPEMCRFCLASYLTLPFRTASLEGSLIPAIDRGLTVTNRLGLLGASVTQHPEFEVLLDHLNHPKYDGVRISLSSVRTNTVTVKLAEILTKRDSKSITIAVESGSDRLRKIVNKKLTNDEIIQAAINAKAGGLKGIKLYGMAGIPGEEMDDLEATVAMMRAVKKAAPGLRLTFGCSTFVPKSHTPFQWFGVNKDAEKRLKFLDKELRKLGLEFRPESYNWSVIQGLLSKGDRRLSKLLELVRHYGDTLGSYRRAFKELRGQLPEMDFYVFQEWELERVLPWSHLKGPLPEATLKKHLAEAMTQSILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV07</accession>
    <name>A0A2G4EV07_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000209">
        <property type="protein sequence ID" value="PHX53365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53365">
        <property type="protein sequence ID" value="PHX53365"/>
        <property type="gene ID" value="CP500_021895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7534" checksum="8A3E2321369B704C" modified="2018-01-31" version="1">MNKDETGIEDELQPEYDLRSLRLRKVGSGRKSFGGVNIRLEPDVAEIFPDSEAVNEALRFLIRITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV28</accession>
    <name>A0A2G4EV28_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen synthase</fullName>
            <ecNumber evidence="7">2.4.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Starch [bacterial glycogen] synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glgA</name>
        <name evidence="10" type="ORF">CP500_021725</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Synthesizes alpha-1,4-glucan chains using ADP-glucose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000203">
        <property type="protein sequence ID" value="PHX53393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53393">
        <property type="protein sequence ID" value="PHX53393"/>
        <property type="gene ID" value="CP500_021725"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033201">
        <property type="term" value="F:alpha-1,4-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:starch synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_5" evidence="9">
        <location>
            <begin position="3"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="8">
        <location>
            <begin position="295"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ADP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="491" mass="56853" checksum="815F079D64B4A537" modified="2018-01-31" version="1">MYIVQIASECAPVIKAGGLGDVVYGLSRELENSGHAIEIILPKYDCMRYDHIWGLHVAYEDLLVPWYGGEIRCTVFCGWVHGQLCFFIESHSQDNFFNRGCYYGCNDDNMRFAFFSKAALEFLLRTNKRPDIIHCHDWQTGLVPVMLFEIYKYNWMEYQRVCYTIHNFKHQGMGGSEVLQATGLNREDYYFHYDRLQDNFNPFAINFMKGGIVYSNFVTTVSPHHAWEAHHGQFGYGLGHTLHLYQDKFRGVLNGIDYDVWNPESDRYIPQHYTQEDLAGKAKTKEALRDRLLLRDADKPIMAFIGRLDDQKGVHLVHHAIYYALNKGAQFVLLGSATEARINAHFQHEKLVLNDNPDCHLELGFNEELSHLIYAGSDLIVVPSNYEPCGLTQMIGLRYGTVPVVRGVGGLVNTVFDRDYDTNHLPEVRNGYVFYQSDYYALESAIDRAIGLWYDYHDEFEKLIVQGMNCNNSWKYPAKDYVEIYELIRHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV50</accession>
    <name>A0A2G4EV50_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylate/guanylate cyclase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000218">
        <property type="protein sequence ID" value="PHX53310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53310">
        <property type="protein sequence ID" value="PHX53310"/>
        <property type="gene ID" value="CP500_022190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="81"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="329"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="525" mass="56723" checksum="73D0F009E7B7DD2F" modified="2018-01-31" version="1">MVEINRLTYNTPLAELELRLRSLLPASLYAAAWVDSSPATLMSVFDHLRTLRYILHDYVPKQVSESPPNPGEVSYQWQKGTLLFTDLAGFTSLLEANAALGGKGAQTLLGVINDYFASMIEIVSKSGGDLLEFTGDAMLVQFLTDIHQEDTARAVRAGLRMQRAMAKFACIETARGVLSLKMRVGIHSGRYISADIGTPLRMAHVLLGHSVQQAKQAEGSGTVGRVCLTTNSSLCLGEQFRFEPVAPGYVLVVDDLTDDRLGEYDITLTRRRMRSSVLLDRSISGLVSEIQEAVKRVEPLTSYIPKPILKLLVENANKRKIPPDFPEPTVMFVNLIGLPDSMDKASPQEEVALIVACSRVFSSIDAVVSAKGGVLQKVTAHLNGSDMLIYLGVPDSHTDDPCRAATAALAIRDIIAALPPAIIDAQAVNVTCQIGLSQGPVFAAEVGEPRGRREFNVLGDTVNTAARLMSKAGENEILITQRVFEAIDLEFNCEALGAVSLKGKSALTPIFALYGSKVEKGKGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVB8</accession>
    <name>A0A2G4EVB8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2442 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53406">
        <property type="protein sequence ID" value="PHX53406"/>
        <property type="gene ID" value="CP500_021685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018841">
        <property type="entry name" value="DUF2442"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10387">
        <property type="entry name" value="DUF2442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12480" checksum="2F9F9AFB1AED661F" modified="2018-01-31" version="1">MTTLILETEPLVIKVTVTDEKVIVDLADGRSLSVPLAWYPRLLHGSPQERHNWQLLGDGYAIEWTDLDEHIGVEGLLAGRRSSESQRSFESWLIARKTARSNPERLITND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVF0</accession>
    <name>A0A2G4EVF0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000184">
        <property type="protein sequence ID" value="PHX53522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53522">
        <property type="protein sequence ID" value="PHX53522"/>
        <property type="gene ID" value="CP500_021060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="12156" checksum="7955DB853C739F3D" modified="2018-01-31" version="1">MNIQLVDSLIQVIESLTPEESLLFQEKLSARAIQSTPGVCGGNARIRNTRIPVWTLVSLHQQGADEAELLQNYPGLCDRDLENAWRYYDRHHEEIDRIIVSHQTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVH7</accession>
    <name>A0A2G4EVH7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000180">
        <property type="protein sequence ID" value="PHX53543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53543">
        <property type="protein sequence ID" value="PHX53543"/>
        <property type="gene ID" value="CP500_020920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="276" mass="30701" checksum="07A47E62E4CEABE2" modified="2018-01-31" version="1">MKATNSRQFSSVAARTLKVVGIILILSALLDCIVLSLPGETSDILNRGWQLAAATQVVDRGIIPLMGIALLMTGFWVDSSTGVSIERRNVWLDLRFWALLLSSFLGLVYLSLVPVHLNNTRLELKDALVQVEREAGQAEGQLEAQIKSPQFKAQIEQLKSQRRSQIAALLQDEGKMAEALKSPEVPKELKAVLQESKNDPKALDKFLEQQAQELPSQARNEISTRRQQKEKELRTRSRNSSLQTGISSLLLAIGYITVGWTGLRSMGIPRFGRRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVJ8</accession>
    <name>A0A2G4EVJ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonuclease P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000194">
        <property type="protein sequence ID" value="PHX53460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53460">
        <property type="protein sequence ID" value="PHX53460"/>
        <property type="gene ID" value="CP500_021375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="41"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="14307" checksum="90296BE6FF08E4AC" modified="2018-01-31" version="1">MGIREEVYYEGGPAPGDLIINLLLALTVVGIPLAVGAIVRALWLRYRITSRRVSITSGWMGGDRTDVIYSDIVKIVTVPRGFGSYGDMVITLKSGSRLELRSMPKFRSVYDYINEKLPAAAQKTNAAQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVQ4</accession>
    <name>A0A2G4EVQ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000178">
        <property type="protein sequence ID" value="PHX53558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53558">
        <property type="protein sequence ID" value="PHX53558"/>
        <property type="gene ID" value="CP500_020875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14339" checksum="8318E2B9E5FE0B0E" modified="2018-01-31" version="1">MSLTNNLEQPAPAPPIAPNNHPGYLTIKKKSVIIKHYWKIFLFMNTQVTLTLSEPVYQQVQTIAQQSDRTIADLLTEIITLSLNQKTTGESILEMIANFTADLTTSEKDQLPTDAAENHDFYIYKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVT3</accession>
    <name>A0A2G4EVT3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000168">
        <property type="protein sequence ID" value="PHX53645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53645">
        <property type="protein sequence ID" value="PHX53645"/>
        <property type="gene ID" value="CP500_020415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="11177" checksum="EE1CCF6F042C6D8F" modified="2018-01-31" version="1">MSQAILNQIVTQFEMLEILELQELEIAIGKYLADKQQATQQNQTQKSVNKKQLFREWDAISDEEAAVIKSEFAAEDLAFAEVALNDYMLRLQQLDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVT4</accession>
    <name>A0A2G4EVT4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1092 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000170">
        <property type="protein sequence ID" value="PHX53629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53629">
        <property type="protein sequence ID" value="PHX53629"/>
        <property type="gene ID" value="CP500_020470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009472">
        <property type="entry name" value="Tab2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34556">
        <property type="entry name" value="PTHR34556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06485">
        <property type="entry name" value="Tab2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="289" mass="32318" checksum="3889738DFB7DD15A" modified="2018-01-31" version="1">MTTIWELDFYSRPIVDERQKKKWEVLICESPLNVGDNAESLFRYSQFCPSSTVNSLWLAGAIKEAIASAPKPPEKIRFFRRQMANMITKACQDLDIPVASSRRTLALNLWLEERMRSYYPAQEGYQATVNPSVQFVPETPVALPDALIGEKWAFVSLPIAAFDEMSEWDIGFGEAFGLPMTGLGAETQIPGLIIFSSRATALAGWMSSLELAFLKFESSSPIAPARLVLDTGANDRWILANLRDSATEAECKKFEAAKQQAKQVHFLAIQSNPESESFAGFWLLHELNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVY2</accession>
    <name>A0A2G4EVY2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53337">
        <property type="protein sequence ID" value="PHX53337"/>
        <property type="gene ID" value="CP500_022045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018977">
        <property type="entry name" value="NurA_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09376">
        <property type="entry name" value="NurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00933">
        <property type="entry name" value="NurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NurA" evidence="2">
        <location>
            <begin position="81"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="405" mass="45400" checksum="073926E501072AC4" modified="2018-01-31" version="1">MLDLTKAAKAMQGMSQHLTVEAQAARQRLEVAQNLLEKAAARQEELVELQESWRDRTLFNSATPIEPLGDRTYIPAPPTAHTVFATDGSQISPNHHEIAYCYLLNIGTVMLHYGQSRHPVLDSIPEVFYKPEDLYISRQWGIRTEEWMGYKRAVSEAIFLAEMGENWSKVNNHKFPAPTLAMVDGSLILWFLEALPTEARDLILQPILEAWDKLRIAQIPLLGYLSASRSSESLSFLRFEACTHEVPDCITNCPNVGFAATVSFAEKAPCQVFEPLRDVILWATILLPGQRSPFWKSQSRILDLYGLNSVYFCYVHVGTEIARIEVPEWVVEDSAQLDLALGMMLAQVHKGGGYPVTLAEAHNQAVVKGGDRGRFFALLEQQMIKAGLKNVGISYKETRKRGSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW07</accession>
    <name>A0A2G4EW07_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53704">
        <property type="protein sequence ID" value="PHX53704"/>
        <property type="gene ID" value="CP500_020095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="96" mass="11121" checksum="6683F54C091FE51A" modified="2018-01-31" version="1">MRPWQNWLDTLILSTQHNPPRFVELVMLTLAMILLGLWTFTGKWPYLALSLSYIIGSSFSILVRESLGPRPQFQLTHLTALLLLIISFYSFAELIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW34</accession>
    <name>A0A2G4EW34_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c biogenesis protein CcsB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ccsB</name>
        <name evidence="6" type="synonym">ccs1</name>
        <name evidence="9" type="ORF">CP500_020225</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">May interact with CcsA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cellular thylakoid membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Ccs1/CcsB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000164">
        <property type="protein sequence ID" value="PHX53670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53670">
        <property type="protein sequence ID" value="PHX53670"/>
        <property type="gene ID" value="CP500_020225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01392">
        <property type="entry name" value="CytC_Ccs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023494">
        <property type="entry name" value="Cyt_c_bgen_Ccs1/CcsB/ResB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007816">
        <property type="entry name" value="ResB-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31566">
        <property type="entry name" value="PTHR31566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05140">
        <property type="entry name" value="ResB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="ResB" evidence="8">
        <location>
            <begin position="33"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ResB" evidence="8">
        <location>
            <begin position="369"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="470" mass="52467" checksum="1AB734211734BAEE" modified="2018-01-31" version="1">MISKEVFISKLSNWANAPQKFFKRDVLPVLADLRLAIILLLAIAIFSISGTVVEQGQSVEFYQSNYPEHPALFGFLTWKVLLIAGLDHVYRTWWFLSILVLFGSSLTACTFTRQLPALKIARRWKFYEEPKQFQKLALSAELETGSLTSLEQLLQQKSYRIFREGDKVYARKGIIGKIGPIIVHASMLLILAGAIWGTMTGFMGQEMVPSGQEFRVQNITDAGPWAGPQIPKDWSMRVNRFWIDYSPSGAIDQFYSDLSVLDKTGQEVDRQTIHVNLPLKYRGVTFYQADWAIAAVRVRLNKSPVFQLPMAQLDTQGKGRIWGAWIPTKPDLSAGVSLLAKDLQGTMLVYGTDGKLLTTVRAGTAVEVNGVMLTIDEVVGSTGLQIKADPGIPIVYTGFGLLMLSVMMSYLSHSQIWALEKDGKLYVGGRTNRAQVTFEREVVEILDKLAESKLDEDKSTITETSLANQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW83</accession>
    <name>A0A2G4EW83_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000154">
        <property type="protein sequence ID" value="PHX53795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53795">
        <property type="protein sequence ID" value="PHX53795"/>
        <property type="gene ID" value="CP500_019590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="84" mass="9770" checksum="302056B371F0D98A" modified="2018-01-31" version="1">MRTPDFLVNSFLQKFTIPYRGISADFVFTGFTHGGPKTRFLREYLSKKSTIFGRNRVFLALVLFQKPHIWGFLISIINNLRSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWK0</accession>
    <name>A0A2G4EWK0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anthranilate synthase component I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_018810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000139">
        <property type="protein sequence ID" value="PHX53932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53932">
        <property type="protein sequence ID" value="PHX53932"/>
        <property type="gene ID" value="CP500_018810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="3">
        <location>
            <begin position="28"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="2">
        <location>
            <begin position="274"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="548" mass="60862" checksum="D5EEFFFC310E31B8" modified="2018-01-31" version="1">MIFPDFSQFSELAKQGNFVPVYQEWIADLDTPVSAWYRVCADQPYNFLLESVEGGEKVGRYSLLGCDPLWILEAKGDRTTQVYRDGSQKVFTGDPFAALTECLEPYKPVKLPQLPPGIGGLFGFWGYELIKWIEPRVPVYPAGEKDLPDGLWMQVDNLLIFDQVKRKIWAVAYADLRDVGVDLAEAYGQACDRVSRLVDKLKSPLSRQSTLIEWTPPNDGQDARSTSNKNGQDARSTSVKDGQDARSTSGKDGQDARSTTDNTELSYTSNTTPEKYCANVIKAKDYIKAGDIFQVVISQRLESEYSGDPFALYRSLRLINPSPYMAYFNFGDWQIIGSSPEIMVKAENTPDGKRIATLRPIAGTRRRGKTAQEDEALAAELLQDPKEIAEHVMLVDLGRNDLGRVCRSGTVKVDELMGIERYSHVMHIVSNAIGELAEDKTAWDLLKAAFPAGTVSGAPKIRAMEIVHELEGCRRGPYSGVYGYYDFEGQLNSAIAIRTMVVRSLGDDKHSVSVQAGAGLVADSNPEMEYEETLNKARGMLQAIRCLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWN3</accession>
    <name>A0A2G4EWN3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3464 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000145">
        <property type="protein sequence ID" value="PHX53876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53876">
        <property type="protein sequence ID" value="PHX53876"/>
        <property type="gene ID" value="CP500_019110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021855">
        <property type="entry name" value="PAM68-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34575">
        <property type="entry name" value="PTHR34575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11947">
        <property type="entry name" value="DUF3464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="180" mass="19622" checksum="9755F23BC5F4BFEB" modified="2018-01-31" version="1">MSSEPPRQRLPFEPAKNRKKTPKKPTEPETANVALEPKSTDKQPKANKIGKIASPSLAPKSADKQPKASKTEKQAQSIPEVVSKRMISRIAVFCGIPTILGISTFFVSYLIVSKGLFDLPNTAVLLVSMGCFGLGVLGLSYGVLSASWDEEISGSILGWEEFNINFGRMREGWRSAKPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX32</accession>
    <name>A0A2G4EX32_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">frr</name>
        <name evidence="5" type="ORF">CP500_017995</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54089">
        <property type="protein sequence ID" value="PHX54089"/>
        <property type="gene ID" value="CP500_017995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="4">
        <location>
            <begin position="18"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="182" mass="20280" checksum="3F98A7306FDE6428" modified="2018-01-31" version="1">MKLAEVEEHMQKAVEATQRSFNTIRTGRANASLLDRIMVDYYGAPTPIRSLANIGTPDASTISIQPFDPKALNLIEKAISLSDVGLVPNNDGSTIRLNIPPLTSERRQEFVKMAGKFAEEGKVAIRNVRRDAVDSVRKQEKSSDISKDESRDLQDKIQKLTDKYIAKIEEVLAAKEKDIVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX39</accession>
    <name>A0A2G4EX39_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="8">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">potA</name>
        <name evidence="10" type="ORF">CP500_017950</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000125">
        <property type="protein sequence ID" value="PHX54104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54104">
        <property type="protein sequence ID" value="PHX54104"/>
        <property type="gene ID" value="CP500_017950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015417">
        <property type="term" value="F:ABC-type polyamine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005893">
        <property type="entry name" value="Sp_pt_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01187">
        <property type="entry name" value="potA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="4"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="362" mass="40566" checksum="10DAE658A169A0C1" modified="2018-01-31" version="1">MHAVQLLDVSKLFKTVRSQDFLAVDNINLQIFDKEFFSLLGPSGCGKTTTLRMIAGFEMPTAGEIHIHGEPMQNRLPFHRPVNTVFQNYALFPHMTVAQNVAFGLEMESLSKQIIRDRVAEMLKLVQLTDVEKRYPRQLSGGQQQRVALARALVKQPSVLLLDEPLGALDLKLRKEMQLELKKIQIILGITFIYVTHDQEEALTMSDRIAVMDGGKLQQVGTPVEIYEYPQTRFVAEFIGDSNFLSGRIVSKQSGKITVLVDQQLPVLVTTTEDLPAGKVVTLVLRPEKVGIYPADYAAENTWLGTVTEAVYIGTDTRYTVQLTAKSSIAIRRQNLHRDDLQRHRVGDSVQVAVPPESICIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX66</accession>
    <name>A0A2G4EX66_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54066">
        <property type="protein sequence ID" value="PHX54066"/>
        <property type="gene ID" value="CP500_018030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="28"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="29752" checksum="E13A0329F39180AD" modified="2018-01-31" version="1">MQNHTLTTFVNNSSQKATYLDIGSGQPLLLLHGFFGEKTCWLPLIELLQSQFRCISLDMLGFGESSKPEICYDVALEVAFVRQVVEQLNIDPCSIIGHSFGGWVASAYALKYTNSVSSLVLAAPAGIRDDSFCGQYDALRPLLWETPIVDLVLQLAKPFANLAGKSNELQQILGWRRELISQPVARSFLMSRMRPEDAIDTVEKDIHKLQIPTLVITGDQDETIPLWHSRTYANQIPKAQLAIIPNATHALPQTQAETIANLICEFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX97</accession>
    <name>A0A2G4EX97_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_017570</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000119">
        <property type="protein sequence ID" value="PHX54164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54164">
        <property type="protein sequence ID" value="PHX54164"/>
        <property type="gene ID" value="CP500_017570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="13">
        <location>
            <begin position="3"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="11">
        <location>
            <begin position="165"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="12">
        <location>
            <begin position="290"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX54164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="363" mass="41232" checksum="F37DE1D4A0AB984D" modified="2018-01-31" version="1">MFAIKRALKLNNQEATLLAKHAGFRRVVFNMGLSLRTQMYGEAKLSDNKVINEVKKVLTNYVKKQPQFNWMNQLSSRVYQNALIDLKDAFSRYRSGKSGHPRFNRRRDGQSFTVDSSNGKVLLAAGNTIKIPTLGTFRLHEPLECSVVSQTFTLSKSGSRWFVSFCVDADRLPDQQLQDSVGIDVGIKSFATLSNDRVFDAPKPLKQAKTKLARLQRKASKQVKGSNNQRKTYNKIRRIHARISAIRKDFIHKLTTYLAKSFQLIKIEDLNVKGMMANHKLAGAISDLGFYEFQRQLEYKCQMYGASLVLVDRWFPSSKLFSNCGSKKEMPLNLRTYDCPVCGRSIDRDLNASLNILNSQPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXB8</accession>
    <name>A0A2G4EXB8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000119">
        <property type="protein sequence ID" value="PHX54171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54171">
        <property type="protein sequence ID" value="PHX54171"/>
        <property type="gene ID" value="CP500_017615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="12639" checksum="432C12C7F195E1BC" modified="2018-01-31" version="1">MQEKQKVTLYLSPELHRQLKIKAAVESEPMSSIAERAIVFYLGNSELVDEVEASYGQTHRVYTCPECTGSVVMRDGELASLTSQPTVLAEQELPVKQVSGVSASTALPGEEELVPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXH2</accession>
    <name>A0A2G4EXH2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54229">
        <property type="protein sequence ID" value="PHX54229"/>
        <property type="gene ID" value="CP500_017340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="14566" checksum="DA08E870086599B5" modified="2018-01-31" version="1">MLGNFQQSNLRIELEASETAIRDSLLRPSQLQQWLWPQQLSSGLPEEFAQGLTFTSWLGPVAVQHHVDIAEPNCLRLLLSQGIDGFHEWYWGDGWVQSRLEGVSLLPLNLGQTASLLRLREFLGKGKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXI4</accession>
    <name>A0A2G4EXI4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000117">
        <property type="protein sequence ID" value="PHX54186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54186">
        <property type="protein sequence ID" value="PHX54186"/>
        <property type="gene ID" value="CP500_017485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8658" checksum="20387EBA088236AC" modified="2018-01-31" version="1">MPKRNVIPLLLLVTALFITYGDSWKFLPKPARNASVTSRKFLLGLWPSWVKPKDLNQQRQRELDELQKTPTPNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXW4</accession>
    <name>A0A2G4EXW4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54318">
        <property type="protein sequence ID" value="PHX54318"/>
        <property type="gene ID" value="CP500_016725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039018">
        <property type="entry name" value="VapC20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42188">
        <property type="entry name" value="PTHR42188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="6"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="137" mass="15750" checksum="59EEF4A96C687DD3" modified="2018-01-31" version="1">MTPIKIFIDTSFIIALINERDQYHNQALSLADQYDTQLLVVTDSVLLEVANALSRRYKFEAIQVIEDLLTSEDVEVVRLTPELFDRAFQLYKTRQDKAWGLVDCISFIVMQDRGISIAFTFDQHFAQAGFQILPSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXW9</accession>
    <name>A0A2G4EXW9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_016575</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54369">
        <property type="protein sequence ID" value="PHX54369"/>
        <property type="gene ID" value="CP500_016575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="169"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="285"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="43455" checksum="3CC66E77981C5069" modified="2018-01-31" version="1">MKTLKFKLYQSKRNKHLKRSINAAGVIYNHCIALHKRYYRMWSKHLNCAKLQAHIAKLRKRKAFWQSVGSQAVQDICQRIERAYQLFFKHHKKGVRPPNFKKVRRYKSFTLKQAGYKFLTGNRIKIGNRVYQYWNSRPIEGTVKTLTIKRTPLGELFMVIVVDGVVEPETKFEMSRIAGFDFGLKTFLTCSEDSKIESPQFLKQSLNVIKKASRRHSKKRKGSANRERARLNLVRKHEDVVNRRSDWFWKLAHDLTTHFDVLCFETLNLKGMQCLWGRKISDLAFGEFLQILEWVATKKGKQVVFIDQWYPSSKTCSNCGHVLKELDLSVREWRCPSCQSINGRDENAAKNICAVGVSTVKLGDVRQATPAIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXX1</accession>
    <name>A0A2G4EXX1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3177 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54371">
        <property type="protein sequence ID" value="PHX54371"/>
        <property type="gene ID" value="CP500_016585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021515">
        <property type="entry name" value="DUF3177"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11375">
        <property type="entry name" value="DUF3177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="206" mass="23178" checksum="3831AADFA8128B37" modified="2018-01-31" version="1">MLSLLLAATGPWFQPLVWMDYRLSVLLTVSIPLVVLIWAVVEKAEAIVRLSIIYWRVASLLTITLYLMMAALPVSFVSSVIGRALIPASLWFWADLNEEIADRPQSPLKLAFTAWRWAITVYSGLGAIAQIPFLTCAFKSQNQVIDEPFCRIWLDPPWLYKQMFHATSTPTFLGFLAMAGLGIYVVYLSYFVLIRLGKQGRSATGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY37</accession>
    <name>A0A2G4EY37_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CP12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54370">
        <property type="protein sequence ID" value="PHX54370"/>
        <property type="gene ID" value="CP500_016580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039314">
        <property type="entry name" value="CP12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003823">
        <property type="entry name" value="CP12_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33921">
        <property type="entry name" value="PTHR33921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01093">
        <property type="entry name" value="CP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP12" evidence="1">
        <location>
            <begin position="9"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="8650" checksum="5254722D80A28B7F" modified="2018-01-31" version="1">MTTTPAGNIQEKIEEEVENARTVCDVIGNTSGECAAAWDAVEELQAEASHQKQVKPKNSFEKYCDENPDAAECRIYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY71</accession>
    <name>A0A2G4EY71_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54428">
        <property type="protein sequence ID" value="PHX54428"/>
        <property type="gene ID" value="CP500_016220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="197"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="377" mass="41907" checksum="D0BF839C7B37BDEB" modified="2018-01-31" version="1">MKIALFTETFWPKIDGIVTRLIHTVDHLQRSGEQVLIFSPDYGITEYKGARVYGVEGLPFPMYPELKMALPSPAIGRELEQFKPDIIHVVNPAILGLGGIYYGKKLDIPILASYHTHLPKYLHHYGFGMLEPLLWELLKGAHNQAELNLCTSTAMVEELRSHGIDRVDLWQRGVDTEMFVPELASREMRSRLSQNHPDSPLLLYVGRLGAEKEIEAIKPVLEAIPNARLALVGDGPHRQTLEQYFADTPTNFVGYLKGQELASAYASADAFIFPSRTETLGLVLLEAMAAGTPVVAARSGGIPDIVTDGVNGYLFDPTDEQGATVATQRLFANPEERENLRQSARREAERWGWAAASAQLRRYYQSAIFAQSMSSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY86</accession>
    <name>A0A2G4EY86_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54492">
        <property type="protein sequence ID" value="PHX54492"/>
        <property type="gene ID" value="CP500_015760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="7781" checksum="837407ECC49C874C" modified="2018-01-31" version="1">MFLDELIPVAKELLEQPIAFTGGFVSGLLRLNLQEDPVKSWIDEQTGSTSYTPPASETTNGKSNGPQSISID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY94</accession>
    <name>A0A2G4EY94_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Filamentous hemagglutinin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54503">
        <property type="protein sequence ID" value="PHX54503"/>
        <property type="gene ID" value="CP500_015815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008638">
        <property type="entry name" value="Filamn_hemagglutn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05860">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00912">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01901">
        <property type="entry name" value="adhes_NPXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013875278" evidence="1">
        <location>
            <begin position="23"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="domain" description="Haemagg_act" evidence="2">
        <location>
            <begin position="31"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="935" mass="95379" checksum="5080B7CC5A03ADC1" modified="2018-01-31" version="1" fragment="single">MRRLKFTLLFAALVLSPFPAIAQIIPDSSLGNESSRAVSDTINNLPIDRIQGGATRGSNLFHSFGEFNIGEGRGAYFVNPNGISNIFTRVTGNNQSNILGTLGVQGNANFFLINPKGIVFGPNARLDLRGSFIGSTADSIVFNNGFEFSSTNPQTSPLLTVNIPVGLRFRDNPGAIVNRSIATGQINQPKLPLETPITNQVGLAVDPGQTLALIGGSVQLPSGNLTASGGQIVLGSLDSSGLVNFAQTPLGLTFNYNNIQNFGNIELSAGSVINTSGVGGGKVDIRGGNVSLNGSRIYAMTLGNIDSRGIDINSQNLQIKDGAQISTLTLGDGAGGNINIRATDSVEMSGLGVEGYQQVVIKYLVSGTTDPFDPQFVLFNGTSGAGAGGSITIDTPSLLMRNGVVGSGITLGAGSGGNLNIRANTFEMVGSGINNATAKDTTGAGGNINLDVQRLIMRDGSLLGSTNYSSGPPGNITIKAAESVELFNSSSKTAVSTGISTLSIGGNGRAGDITVDTKRLSLSGGSAFTLGTGVSIGRFLFSRNGGPAGSLKVTASESVEIAGISPLLTGGNQTTSALTSATLSSSRGGNIRVDTPRLTVRDGGIISVRSLGVGDVGDITINADRIEVIGSVNNGLSVSSIDASVGQVFGNNPNATGNAGELNINAGRLIVRDGATITVQATGTGRAGNINVVADAIALDNKGRIDGTTVSGTGANINLQAQSIQLRRGSRITTDAGTSEGGNINLRSDILVALPGENSDITANARSAGGGRVNVNVPNVFGFRAVGREEVRSSLGLTDAQFAQLQVSPTSLISTSDIAAISQTGGPALQGTVTFSSSGVNPAQGLVELPQNVTNSEQLIVANPCIQAAENAFTVTGKGGVPPSPNDSLSSESVPFAWVEFSEGSRIPLQGRGGEAGLFHSQQKTQMMGERGRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYG7</accession>
    <name>A0A2G4EYG7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system HicB family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54569">
        <property type="protein sequence ID" value="PHX54569"/>
        <property type="gene ID" value="CP500_015405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031807">
        <property type="entry name" value="HicB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15919">
        <property type="entry name" value="HicB_lk_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HicB-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8018" checksum="6B86CBC618328393" modified="2018-01-31" version="1">MNYPYSLLIQWSQEDGLYLVTLPEFAKLAMQPSTYGKTYEEAIANAKEAIASYLEYCQEEGLVPPNPAIVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYJ9</accession>
    <name>A0A2G4EYJ9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="7">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">metG</name>
        <name evidence="11" type="ORF">CP500_015100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54603">
        <property type="protein sequence ID" value="PHX54603"/>
        <property type="gene ID" value="CP500_015100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01228">
        <property type="entry name" value="Met_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="PTHR43326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="9">
        <location>
            <begin position="12"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1g" evidence="9">
        <location>
            <begin position="150"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_3" evidence="10">
        <location>
            <begin position="405"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="7">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="307"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="535" mass="60686" checksum="B73320EAE7DCDF4D" modified="2018-01-31" version="1">MKSTDKTKNTFAITTPLYYVNDLPHLGSAYTTMAADAIARFERLRGKSVLLITGTDEHGQKIQRTAESLGRSPQAHCDLVVPGFEALWEQFNIQYDRFIRTTARRHEYIVKEFFQRVWNSGDIYLNQQQGWYCVSCEEFKEERDLLPGHRCSVHTSKEVEWRDEENYFFRLSRYQDQLLALYQERPDFIAPESRRNEVLSFVNSGLQDFSISRVNLEWGQPVPVDPSHTIYVWFDALLGYITALLDPDSDPTLESALSKWWPIDIHLIGKDILRFHAVYWPAMLMSAGLPIPGRIFAHGFLTKDGKKMGKTEGNTLDPVALVNKYGADAARYYFLKEIEFGQDGDFNETRFINTLNAELANDLGNLLNRTLNMARKYCGGDVPNVLGESISSDNLLKGMSLNLGEQVAGYYEDLAFSKACEAILALVRAGNKFIDVQAPWSLYKQGQLESVQQVLYSVLESVRLASYLLSPIIPNISSAIYQQLGFSIDFNDYLKVNCLATFATHSVWGALPANQALGEAQPVFKRLELLEKVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYL4</accession>
    <name>A0A2G4EYL4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54611">
        <property type="protein sequence ID" value="PHX54611"/>
        <property type="gene ID" value="CP500_015140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="10021" checksum="CD21DF99D454334C" modified="2018-01-31" version="1">MNIEEVLEKKGIIHSNPEIMSGVSVFVGTRVPLQTFFDYLEGEEGLAEFINDFSYLENQAIKVLENLAKMMISRERGSNVYTSTHLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYL8</accession>
    <name>A0A2G4EYL8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54267">
        <property type="protein sequence ID" value="PHX54267"/>
        <property type="gene ID" value="CP500_016990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02955">
        <property type="entry name" value="SSP411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004879">
        <property type="entry name" value="DUF255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024705">
        <property type="entry name" value="Ssp411"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42899">
        <property type="entry name" value="PTHR42899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03190">
        <property type="entry name" value="Thioredox_DsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006402">
        <property type="entry name" value="UCP006402_thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredox_DsbH" evidence="1">
        <location>
            <begin position="3"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="719" mass="80314" checksum="C5AD50A212EC4B99" modified="2018-01-31" version="1">MVNRLAQSQSLYLRKHSENPIDWWPWCDEALETARSENKPIFLSIGYSSCHWCTVMEGEAFSDRAIAEYMKSHFIAIKVDREERPDIDSIYMQALQMMIGQGGWPLNIFLTPDERIPFYGGTYFPVEPRYGRPGFLEVLQAIRRFYDTEKGKLETFKSEILGNLQQGAILSGVTAELNSELFQKGLEANTAIISSGNRAPCFPMMPYAELALRGIRFDFDSSKYDAQQACAQRGLDLALGGIYDHVAGGFHRYTVDETWTVPHFEKMLYDNGQIVEYLANLWSAGIQEPAFETAIAGTVEWLKREMTATNGYFYAAQDADSFTPPTPPYQGGAENLTPPYQGGAENLTPPYQGGATGGSEPEEGVFYVWTYSELEQLLTAEELGEIEQQFTVSRAGNFEGKNVLQRRHYEKLSETVETALAKLFAVRYGGHPDTVKTFPPARNNQEAKNDSWPGRIPAVTDTKMIVAWNSLMISGLARAAAVFGNSEYLELAVKAADFILDNQWIDGRFHRLNYDGETAVMAQSEDYALFIKALLDLHQGSLSLVTGSEKWLQKAVEVQAEFDEFLWSVELGGYYNTAKDASADLLVRERSYTDNATPAANGIAIASLVRLALLDQNLEFLDRAQQGLQAFSSIMQDAPQACPSLISALDWYQHSTLIRTTHELISGLIWQYYPTAVFQVEADLPEGVVGLVCECLTCKEPAKSQGQLLAEILQSQTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYR2</accession>
    <name>A0A2G4EYR2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54626">
        <property type="protein sequence ID" value="PHX54626"/>
        <property type="gene ID" value="CP500_015190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="159"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="452" mass="51827" checksum="FB4A2BC4526BF3C1" modified="2018-01-31" version="1">MLKMADEMVFAKTGQHLDNLQEAILRGTMQGETYTQIAKEKHCDESYVRDVGSKLWQILSEELGQKVKKSNFRAAIERLQVSLFSNVVQDHVRARNINFCAEARHPPNIPNSHPPNQETANPQQTKTSHQDLSEMPELGDFYDRTPQLQTLTTWILQQHSRLITLTGISGIGKTTLAVKLVQQIKDEFEYVIWCSIDASHTPDEFEHKLIQLFSQSEKQDLSLTNQKRLPLIKYLQKHRCLVVLDDVQNLFCSGESAGKYKPEYEEYRSLFKQIEKLSHQSCFLLIGWEQPREVTQFKNPNTPLRTLQLKGLDIAAGWEILRDCGLEEIDNSEALIHRYQGNPLWLKSVANLIQELGIGVTELLLDDSILLPEDLKDVLQQCDRTSELEKQVMSLLARENQPVNLAKLLEKAQISSSNLLNALQSLSRRCLIEKQESLYSLPPVLKQYIKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYR3</accession>
    <name>A0A2G4EYR3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">L-threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">ilvA</name>
        <name evidence="13" type="ORF">CP500_014945</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54653">
        <property type="protein sequence ID" value="PHX54653"/>
        <property type="gene ID" value="CP500_014945"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:L-threonine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="8 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="329"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="423"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX54653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="503" mass="55593" checksum="69562AAE89A70508" modified="2018-01-31" version="1">MLCDYLVQILTARVYDVAQETPLEVAPNLSARLNNQLLLKREDMQSVFSFKLRGAYNKMAQLSPELLAKGAIAASAGNHAQGVALAARHLGTRAVIVMPVTTPQVKVNAVIARGGEVVLHGDTYDDAYAFARQLEAETGMTFVHPFDDPHVIAGQGTIGMEILRQHQKPIHAIFVAIGGGGLISGISAYVKRLRPEIKIIGVEPVDSDAMNQSLKAGKRVRLSQVGLFADGVAVREVGEETFRLCQQYVDEIILVDTDDICAAIKDVFEDTRSILEPAGALAIAGAKAYVEREQIAGETLIAVACGANMNFDRLRFVAERAEFGEHREAIFAVTIPEQPGSLRRFCECLGKRNLTEFSYRIADEKAAHIFIGVQIQNRADAIKIAASFEDCGFKTLDLTDDELTKLHLRHMVGGRSMLADHELFYRFEFPERPGALMKFVGSMSPNWNISVFHYRNNGADYGRIVVGIQVPPDEMKEWQAFLDTLGYQYGDESQNPAYKLFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ33</accession>
    <name>A0A2G4EZ33_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54784">
        <property type="protein sequence ID" value="PHX54784"/>
        <property type="gene ID" value="CP500_014215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="317"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="695" mass="78702" checksum="9DB6A8DBEE22EDC2" modified="2018-01-31" version="1">MTQNNLASAYLYKITGNKAENLDEAIRCYRLALEFRTPTTLPLDCLQSGRNLGNLAFKEGLWKIAIEGYAAAILAVEKSRSWSTTDASRQQIIADSIDVYENIIQAYINSGNLNKAIEYVDRSSSKRLVDLMASNDLYAGGEIPSQVQEYLQQYDNIQALIDTGRKPLQGDTNSSQQPTDKRSFALTRDAVEAATATLKTLEAQKQQIWEQMRRLDPVLAGEIQVTPLDFRTIQQLIEQPKTAIINFFTTDNDTHIFIIYKHKKPKLYTCTGFGYQTLRALVDDEWLTPYSNKKDGIWQAKISDFLQQISEKLQLKTLVQTYLKDIEELIIIPHLYWHQIPFAALPLTVPNQNNSQPPENQPSGIIREAIKISTRLEKKNTITNISIPPESETISTEYLGDKFRIRYVPSSQILQYCQQRPPLSEINYGTVENADDTLPNAQFECEQIAQFYNIPENLRLKGRSQATVSNYRQLAKQVQVLHSSHHAKSCLDSPLESCLLLADGKITLGQIMSPGFRLPNLSDVFLSCCETNLGVAGVSDDILSLSTGFLCAGARSVVSTLWSVDDLATALFCIFYYQNRRQGLNRPEALRKAQIELRTMTGKTLADQYQSDLNTYLKQQLKQLDTVYLEAEAQLKQQAKNTDGYRKWEAEVDRLTIIDIRMRNQIKKVLPSLCLEAFPFAKPFYWAGFICSGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ56</accession>
    <name>A0A2G4EZ56_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3859 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54791">
        <property type="protein sequence ID" value="PHX54791"/>
        <property type="gene ID" value="CP500_014075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="207" mass="23467" checksum="62E7380A4D7659B1" modified="2018-01-31" version="1">METRLTQTQLAQVVAEIDKLSQQRELELAPDQVREILRELNLPDELLEDAIAQMHRREALEKQQRRYRWIAIASTAVVISAIAMGVLFGQNRQQQNAQVVATEDRIALSKKGGDSLTQVNRQINPRIYYQVTLKNAPIGNQLSLQCDWTNPSGNIVHQSKYQTRTIDTAVWNTYCFYDLGSASPPGNWEVRMSLDGRAIGSEPFVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZC9</accession>
    <name>A0A2G4EZC9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54876">
        <property type="protein sequence ID" value="PHX54876"/>
        <property type="gene ID" value="CP500_013645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8733" checksum="F6DA6DB394FBF163" modified="2018-01-31" version="1">MKLPDRITTYKYPIKSHVEIEAEFNSLVSEETVDYNCFAFVAGEVEQKYYNYLTGYGMTGLQQPTSATANPKTTKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZG1</accession>
    <name>A0A2G4EZG1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="3 4">N5-CAIR mutase</shortName>
            <ecNumber evidence="3 4">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">purE</name>
        <name evidence="7" type="ORF">CP500_013565</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="3 4"/>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54911">
        <property type="protein sequence ID" value="PHX54911"/>
        <property type="gene ID" value="CP500_013565"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024694">
        <property type="entry name" value="PurE_prokaryotes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001338">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 3 4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="6">
        <location>
            <begin position="4"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001338-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="18449" checksum="FAF9464EB083E52A" modified="2018-01-31" version="1">MNQPTVGIIMGSDSDLPTMKDAIAVCEEFNIPCEVAIVSAHRTPECMVEYAKSAHSRGLKVIIAGAGGAAHLPGMVASLTPLPVIGVPVPSRHLQGIDSLYSIVQMPAGIPVATVAIGNSKNAGLLAVQILAVHQPELLERVLHYRKTLSESVMEKQKRLAELGYHHYLDGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZL0</accession>
    <name>A0A2G4EZL0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclic nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_013400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54945">
        <property type="protein sequence ID" value="PHX54945"/>
        <property type="gene ID" value="CP500_013400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="8"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="156"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="364" mass="40949" checksum="5A69DE400C95DF73" modified="2018-01-31" version="1">MDLVSHRFMSYFGPEQAAHLCKIAILEHFDQETLVFEEGDAADFLYLVLEGEVKFSKRIENNKHQSVAVAKPDDFFGELGVLDGQPRSARALAIRGSTLAKIGREELIETLRFSQGSSVLEIFSFIIKNLRDTTDQYVNQFVHKQKMVLVGEMVSTIIHDFKSPFTVIKLSSEMLKEIHPDEETQEWCELIQLQVQRMLGMAEEVLEFSRGNAVLNKKPANFIQILHQFKKLNKVYFDAAKVDLVIRVTEVVAIVDENKILRVLQNLVGNAVEAFGGRGGRVEITVTQSEDWVEISIYDNGPGIPAAIKGKLFEPFVTYGKRTGTGLGTAIAKSIVDAHQGEITYESENYKGTTFYIRLPKNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZR5</accession>
    <name>A0A2G4EZR5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54687">
        <property type="protein sequence ID" value="PHX54687"/>
        <property type="gene ID" value="CP500_014820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025478">
        <property type="entry name" value="COP23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14218">
        <property type="entry name" value="COP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013801052" evidence="2">
        <location>
            <begin position="24"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="208" mass="22572" checksum="F0F72438205FF98E" modified="2018-01-31" version="1">MKLQFVAPLLVSALALTANVALAGQGQTRLISNSLRDTTTTFQCVTSGRSFVTIARRGNVTTDPIIIWKSTEFGREFTPWQRCQIVSNRLTKAVADNGGRLTNLHLTTGNINNLPVVCYVNGRGRCNSQNILFTLDSRNAKNPSQVLTGLINFAQDGGGPATVLRARAGEEVSAQQFVPFGDLVDRSFHSTKNQPSVPVQEPESDRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZY2</accession>
    <name>A0A2G4EZY2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Phosphoenolpyruvate carboxylase</fullName>
            <shortName evidence="10">PEPC</shortName>
            <shortName evidence="10">PEPCase</shortName>
            <ecNumber evidence="5 10">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ppc</name>
        <name evidence="13" type="ORF">CP500_012875</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="5 10"/>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55054">
        <property type="protein sequence ID" value="PHX55054"/>
        <property type="gene ID" value="CP500_012875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PTHR30523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="122"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1036" mass="118342" checksum="A19F7B84E84E2908" modified="2018-01-31" version="1">MTSVLQSPEQAINPTSISHSSAHSQSDLFLRNRLKIVEDLWESVLRQECGQELVDLLGQMRSVNSAEGQATHFRESNVLQLIEKLDLNASIRAARAFALYFQLINIVEQHYEQRDQQLAYSSSNSAGGRMFPKLPGNGMDAPDRPRHREGPAPSKTIWDGTESDIMSKDAGTFHQLFPMLLRLNVPSQQIQRLIDQLDIRLVFTAHPTEIVRNTIRTKQRRMAKILQKLDQVDEKFPLVGTESESPYPVSSWEAAALQEQLMEEIRLWWRTDELHQFKPTVLDEVEYTLHYFDEVLFDAIPELYHRLKQALHASFPYLKPPSYNFCKFGSWVGSDRDGNPSVTPKVTWQTACYQRHLVLCKYISAVKRLNELLSLSLHWSDVLPELLESLDRDKSEFPEVYEQWAIRYRQEPYRLKLAYVLQRLENTRDRNWRLYKGDELQREREALTEHPGMTGLYRSGTEFLTELQLIEHNLVETGLSCRDLENLLCQVEIYGFNLAYLDIRQESTVHSDALNEIAEYLQILPKSYNQMTESERVIWLATELQTRRPLIPAELPFSPKTCETINTFRVLRQMHQEFGPEICETYVISMSHDVSDMLAVLLLAKEAGIYDPATGISSVQVVPLFETVEDLKKAPAVMHEVFQLPLYRALLAGGYASVKDQQLSKGPHPVSLQEVMLGYSDSNKDSGFLSSNWEIQKAQKALQIVAENYGVELRIFHGRGGSVGRGGGPAYKAILAQPGKSINGRIKITEQGEVLASKYSLPELALYNLETVTAAVIQASLLHTGFDGIDPWNEIMEELAAKSRSHYRNLIYEQPDLVDFFHQVTPIQEISQLQISSRPARRGGKKDISGLRAIPWVFSWTQTRVLLPSWYGVGTALQEFLQEEPEEHLKLLQYFYLKWPFFRMVISKVEMTLSKVDLQIAEHYVRELSLPADRERFNALFEQISREFHLIRDLVLTITGHQRLLDGDPSLQRSVQLRNATIVPLGLLQVSLLKRLRQHGNGAVPGVIHSRYSKGELLRGALLTINGIAAGMRNTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZZ8</accession>
    <name>A0A2G4EZZ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54767">
        <property type="protein sequence ID" value="PHX54767"/>
        <property type="gene ID" value="CP500_014385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="318" mass="35300" checksum="A2A8D6EB24E4D841" modified="2018-01-31" version="1">MEPQYSTQDSSAISSIKSPTLFYEWQNYRCAYDVYNPTTATEDSIPLLLIHPIGVGLSRVFWQRFCEGWCKSGNSNPIYNPDLLGCGDCEMPAVACHPDDWAAQLQFFLETVVKKPAIVLVQGALLSVALALAKIEQESGSNLIHGLVLAGPPAWAVMNKHSTERQQRIVWNLLNSPLGNAFYRYARRAEFLRSFSAKQLFGDAGNVDSEWLDALQAGAANPDSRHAVFSFLAGFWRQDYSSTIQKCDRPTLIVMGETASSISQAGKEEKPEERLAQYLANFPNAEGLLMPGRNVLPYESTAEFVSAVADFVNKFNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F061</accession>
    <name>A0A2G4F061_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55149">
        <property type="protein sequence ID" value="PHX55149"/>
        <property type="gene ID" value="CP500_012255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013801051" evidence="1">
        <location>
            <begin position="27"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="19736" checksum="649CA3038D4B20EC" modified="2018-01-31" version="1">MNKKLLVLATSACLLTALVPASVVFGASELSQRQPETQQLAQAGTPVAVNEILPKLKGKTQVPIFIPSSISASQKLYYQITAKADSYTISMEYTADCRGAGACSFGEIRAEKGGEFSTKMEGVTKTLKNVQLAGGMKGVFHNGCGAYCTASVDWKSQGFLYTVAIKNGREADVIKMANSAIQAGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0B9</accession>
    <name>A0A2G4F0B9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55212">
        <property type="protein sequence ID" value="PHX55212"/>
        <property type="gene ID" value="CP500_011980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="163"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="464" mass="52621" checksum="BF2CE7E059CCF777" modified="2018-01-31" version="1">MDVQEVLRFADEMVFAKTGEHLDDLQKAILLGVWEGQKYSQIAETSYCSEGHVRNIASKLWKRLSNVLDEDVTQSNLRSALERRQLFIISENSGNDFFIGNVNVCKDSQSPEVPKDRSPSTPTSDTSKPQTRLDLADAPHISSLCDRTSELATLEKSIVQEKCNLAAILGISGIGKTALSLHLIQKIQHNFEYVIWRSLGHSPPLETTLKNLLEFLLNQPEIELPSSIPDRLSLLMEYLRKNRCLIILDDVQAILSSGQLAGNYRPDCENYSILFRQIGETTHNSCLILNSWEPPREITALKGENSPVRTLQLKGICAATTEIFRQKRLINPETWENLINAYQGNPLWLKIVATTIQEIFRGRVAEFLKYDMLFLGEELAATLHPQINRLSELEKKLISQLSREVNPVSIKQLLKDAELSPWELFNGLQSLGRRSLVEIEEEENETLFNLCPVVRQYVILNPVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0E0</accession>
    <name>A0A2G4F0E0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_011845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55225">
        <property type="protein sequence ID" value="PHX55225"/>
        <property type="gene ID" value="CP500_011845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006486">
        <property type="term" value="P:protein glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929">
        <property type="entry name" value="PTHR11929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="316" mass="36784" checksum="FA66E5BD62FE2045" modified="2018-01-31" version="1">MHPKIIGAITTYPGMNQTDWLWQQTPDNFGKWGKIQMLANHSEPDFLLMYQFDFPQPQKQQSWVDKIRHPSPQNPENDLREKLRGVPKERIIYLIREPPLPEVIEITKANYEQAKLYCGYISGPDDFAPNPNYMPAIWYHSNSFRELDEMPSPTKTKLCSWITSGVSRTANHRHRLDFIQLLQQQELNFDLYGRNLPTWAHCNGTVNNKWHAVAPYYYNLAIENYATNDWYVSEKLWDALLAWCLPIYYGGSAADKLLPAGSFLRLPSLDGKGVEFIQEVIATPDYWHEARDKIAEARQIILHELNLLNWLSNFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0F0</accession>
    <name>A0A2G4F0F0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flagellar motor protein MotB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_011710</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55242">
        <property type="protein sequence ID" value="PHX55242"/>
        <property type="gene ID" value="CP500_011710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="620"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="4">
        <location>
            <begin position="648"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="4">
        <location>
            <begin position="720"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="5">
        <location>
            <begin position="784"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="903" mass="98720" checksum="BCE62A71FB46F6AE" modified="2018-01-31" version="1">MTSQKKNPADDNQLEGLISKPDKSAGDTPAQLKPLVNLLIELKILADSDRGNPESEPEISDENTHTPLLGGLKDLLGISEEVAASESPATFDGEPDSGDSLAFLEEFKKLLFVTQKLSTSELEKDYSSVNTIDILAIGEVELDKEAQQIQDLSNLKIQDSPQEVQTQKSAGNGHNLENFPDRETNPQPSVIPHNPLVPTASEPGEAEYLDAATASALEMPNLLEQPTQISPTEILGQIKQDLNEADSAMEKLQNLIFGSQISDIEQLKTLLAENDLPGVRNLMATIDDKLEKLEHQIYDPQQLIALMLPWIAEILSRKISDSKEEMVQAIVPIIDEVIRAKTQENKHAMSSAIAELLPDALSQQIQNSPAEIAHAIAPEIGLAIKEQIRLDKEAIAQALAPEMGRAITAQIQLERDSMVDALYPVIGSTISKYLAEAIQTINEKVSNALSVEGVQRKIRSKVQGVSEAELILRESMPFTVQGVFLIHKASGLVISEAQNSGDYQLESEMVAGMLTAISSFVNDCIVRPGQISELNQIEYGESKIILEVAGYCYLAAVIKGEPPKQFMKQIRETVSNIIINHGKSVNEFDGNPRSISDDLHPLLISLLGKFTADKQTATKLPIALAGISLAMLSLILVPWGIYQHRSNIDRRLEANARLALSSTPELAVYRLNVDVDGKTLKLTGQLPNPELRAKAAKIVASTVPKLKLDNQIIAVDVPPDPVLTTAEVKRITAVLNRLWGVAISSRYGDRRVTVEGTVMEDGDAQKITQSLKQIPGVESVINTVKLNPLKIATRIYFEPGTAKLDSTYQETIVNIINFLKQHPQKRIKIIGHSDRTGEVATNQQLSIRRAVAVQDALVLQGADPKRLQVVGSDSPPADVEPNQPLLLSRCVRFEPITKSINSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0G1</accession>
    <name>A0A2G4F0G1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tocopherol cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55236">
        <property type="protein sequence ID" value="PHX55236"/>
        <property type="gene ID" value="CP500_011905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009976">
        <property type="term" value="F:tocopherol cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025893">
        <property type="entry name" value="Tocopherol_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35309">
        <property type="entry name" value="PTHR35309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14249">
        <property type="entry name" value="Tocopherol_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="42944" checksum="451A716B527D76FE" modified="2018-01-31" version="1">MSDLPSKHKTIETPHSGYHWDGSYRRFFEGWYYRITLPIHAQSFAFMYSIEDPRGSQPYSGGVAQILGPEDKYLCRTFPDVNKFWAHRDKLGLGHWGRTNLQIKPEYLAPQTFDSHIEEGYQATATLNQGYLHDPGSGKHCYWQYEIKPIYGWGNSAEIQKSTAGILSFLPIFEPGWQILMSHGLATGWIDWNDQRYEFKDVPAYSEKNWGGAFPQKWFWINCNCFQGESDLAITAGGGRRGVLWWMESVAMIGIHYRGKLYEFAPWNSQVSWDIEPWGKWTMRARNSQFEVELIGSTKTPGNYVRVPTAKGMTFCCRDTTHGNLHLQIRELLGGNVDKSGKQRSRIILEAQSSLCGLEVGGGPWDEVWQTNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0V4</accession>
    <name>A0A2G4F0V4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aspartate kinase</fullName>
            <ecNumber evidence="6">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CP500_010975</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55389">
        <property type="protein sequence ID" value="PHX55389"/>
        <property type="gene ID" value="CP500_010975"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04261">
        <property type="entry name" value="AAK_AKii-LysC-BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041740">
        <property type="entry name" value="AKii-LysC-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00656">
        <property type="entry name" value="asp_kin_monofn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="14">
        <location>
            <begin position="273"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="14">
        <location>
            <begin position="362"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="14">
        <location>
            <begin position="449"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="14">
        <location>
            <begin position="534"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX55389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="602" mass="63444" checksum="8CC474480374246B" modified="2018-01-31" version="1">MALIVQKYGGSSVGTVSRILEVAKRVVKTAQLGNSLVVVLSAMGKTTDGLVKLAKEISTNPSKREMDMLLSTGEQVSIALLSMALQELGQPAISLTGAQVGIVTEAAHTRARILRIDPTRIESQLNMGKVVVVAGFQGITDAGEMEITTLGRGGSDTSAVALAAALRADRCEIYTDVPGILTTDPRLIPDAQLMDEITCDEMLELASLGAKVLHPRAVEIAKNYGVPLVVLSSWSEAPGTRVVSPPPQPRPLEGLELAKAVDAVEFDLDQAGVSLLRLPDRPGVAARLFGAIAQQNLDVDLIIQSIHEGNTNDIAFTVTRNSLQQAAAVADAIIPTLGKNSRPELGEPEVKTEERPIAKVSIAGAGMIGRPRVAAEMFKTLADAGINIQMISTSEVKVSCTIDATDCDRAVAELCKTFGVSNSAIGLNSSSPKPAAVRAVALDINQARLAIRHLPDRPGVAAKLFGLLAEENISVDTIIQSQRCHNIDGILTRDIAFTVAQMDAEAAKIVLEKAAPEFGWGEVAVDTQIAKVSVVGSGMVAHPGVAAKMFAALSRQQINIQMIATSEIKISCVVDEEQGITALKAIHTAFELAGTEKIQIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0W5</accession>
    <name>A0A2G4F0W5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55399">
        <property type="protein sequence ID" value="PHX55399"/>
        <property type="gene ID" value="CP500_011030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7576" checksum="2120363D2E955F4A" modified="2018-01-31" version="1">MKDDRPENRDSAKDKVENVVKELKLTKNERQQLHYRLEDYMSYQDILELAKSMFQQNSEGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F129</accession>
    <name>A0A2G4F129_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55461">
        <property type="protein sequence ID" value="PHX55461"/>
        <property type="gene ID" value="CP500_010805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="80" mass="8770" checksum="E92160084EFB1299" modified="2018-01-31" version="1">MGSISFCRVPTISCPYNFAVGTKAKPCPLYHSGAAGIEMKPLQFLSFYLPTADKKAHQSILNEKITDARCLVKYSMALKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F147</accession>
    <name>A0A2G4F147_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABC_transp_aux domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55187">
        <property type="protein sequence ID" value="PHX55187"/>
        <property type="gene ID" value="CP500_012050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019196">
        <property type="entry name" value="ABC_transp_unknown"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09822">
        <property type="entry name" value="ABC_transp_aux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="679"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="ABC_transp_aux" evidence="3">
        <location>
            <begin position="96"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="705" mass="76184" checksum="24140352D2E769AE" modified="2018-01-31" version="1">MKTRKSNWKYIFLLGPLLIAAGVTARLVSAAWEPLTVGLVITGIVTIALWLLYLTYEQGFWGRRSTQASTNALISTLAVFVILGVINFLAFRYPTRIDLTESQQFTLAPQTQQILRNLQNPVKVWIFDPTQNPQIKELLESYKREGGEKFQFEFVDPLAQPGTAREFSITSIGEIYLQSGNKKQVLKKSGTVFGSDPNQGLSEIKLTNGLEEILSTRNPTVYFLQGKGERPLQEGQGGIQQAEKALKDKYYEAKTLNLAERKEVPEDADALVVAGREKPFSDAEIKALKAYLDRGGSLFLMVDPAISTGLDKFLQEWGVKLDSRLAIDYSDTGKKFGLGATVPTVRRYGEHPITQSFGTGISFYPFARPLETTKIEGIEEKPLIWTSEESWAESDLTTKKLEFDPKTDRQGPLLLGVALVRSETANVPSNPSPSPTTSPSPTTSPTPTTSPSPTTSPSPTTSPTPTTSPTTSPTPTTSPSPTTSPTPTTSPSPTTSPSPTTSPSPTTSPSPTTSPSPTTSPSPTTSPSPTISPTQSPTASPISYSVIVSQEATPPLLPETSPTPTASPTVSPTPTPETSPTPTPETSPTPTSEISPIASPKPSPSPASTPSAPSTPRKTSRMVVIGTSQFVTNGWFDQQLNSDVFLNSVSWLSKPDQQSFSISPKKATNRRINMTVVQVLLLVLGWLIWPLLGLGIGTAIWWKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1A2</accession>
    <name>A0A2G4F1A2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha</fullName>
            <shortName evidence="10">ACCase subunit alpha</shortName>
            <shortName evidence="10">Acetyl-CoA carboxylase carboxyltransferase subunit alpha</shortName>
            <ecNumber evidence="10">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">accA</name>
        <name evidence="13" type="ORF">CP500_010545</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the AccA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55533">
        <property type="protein sequence ID" value="PHX55533"/>
        <property type="gene ID" value="CP500_010545"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00823">
        <property type="entry name" value="AcetylCoA_CT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001095">
        <property type="entry name" value="Acetyl_CoA_COase_a_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42853">
        <property type="entry name" value="PTHR42853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03255">
        <property type="entry name" value="ACCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01069">
        <property type="entry name" value="ACCCTRFRASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00513">
        <property type="entry name" value="accA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="13" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="12">
        <location>
            <begin position="44"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="326" mass="35787" checksum="1DB05107E61853C4" modified="2018-01-31" version="1">MPNPDRKPLLLDFEKPLAELEGRIHQIRQLAEENGVDVSDEIRKLEARSAQLRQEIFGSLSPMQRLQLARHPRRPSTLDYVQAISDEWIELHGDRRGTDDPALVGGIARIDGRPTVIVGHQKGRDTKDNIARNFGMAAPGGYRKALRLMEHADRFGMPIFTFIDTPGAWAGLEAEQFGQGEAIACNLREMFRLDVPVICTVIGEGGSGGALGIGVGERLLMLEHSVYTVATPEACAAILWKDAGKANLAAEALKITSWDLKNLGVLDQIVPEPIGGAHSNPLKAASMLKKALLENLAELSGLTSQQRRQMRYQKFRDIGVFTEIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1G6</accession>
    <name>A0A2G4F1G6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55603">
        <property type="protein sequence ID" value="PHX55603"/>
        <property type="gene ID" value="CP500_010015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14195" checksum="0E6FC5D3629F0542" modified="2018-01-31" version="1">MLTEIFPFTFAIDETAIAGASLWSLALYWGLSPLTEWIILQLNRWMNFAERSLYTSETEFERTRQAREAQNAFYASLLSILPFLIVGGLCNWGVELSLGTSWAISMGTIACIGAGVYELGRRDGEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1G8</accession>
    <name>A0A2G4F1G8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55614">
        <property type="protein sequence ID" value="PHX55614"/>
        <property type="gene ID" value="CP500_009790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039060">
        <property type="entry name" value="Antitox_HigA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40455">
        <property type="entry name" value="PTHR40455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="80"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="15378" checksum="192C705C520F47E1" modified="2018-01-31" version="1">MTIGLKTPSRDYIELIVAFPPRPISCEAELIATQNRINSILDRRKLTQDDRDYLNVLGILVYDYEQKHEPMPVLKGIKLLKALMVEAELSEKDLVDIFSTESLVAEVLNGNRELTVSQIQKLAEFFHLSPGAFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1I9</accession>
    <name>A0A2G4F1I9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55616">
        <property type="protein sequence ID" value="PHX55616"/>
        <property type="gene ID" value="CP500_009800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_16" evidence="1">
        <location>
            <begin position="42"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="452" mass="52032" checksum="C55E44CB5083DC5C" modified="2018-01-31" version="1">MTTHPTNRATTLKAAYQLCNVEPLEGEDLDRYYVNLSGVRKTTAIASVNTRLDFQEAGKYTTILFTGHRGCGKSTELKRIQKEWEKDYHVIYLEVNEETDINDVGYTDFYLITIKQVEFEMRRLGLKLDPRLMENFEAWFKDVTQETERTVESSVSVEGEATLGPEAPFLAKLLVKLLAQIKGSDKQKKTIRQTLEKDISRLKADINLLLNDAVKKLRKKFPKYKGFLIIFDNLDRVPPEVANHLFFDYAAQLQQLDCTIVYTVPLSVLSSTKNLNNNFGNPHIVPMVNIYEFNRDDCDLNYNQTGLDTIASLIERRVEIDKIFESREQLLELAKASGGHVRQLMQMMQTACLTASTNEHDKINAEDVIYAIKQEQFNFERFIPQSHYPVLAEVCLTKNITKDDVGQLMLFNTSVLEYNGKNRWNYPNPVVKQSEEFKKALRDARESNVNPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1P8</accession>
    <name>A0A2G4F1P8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heat-shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55397">
        <property type="protein sequence ID" value="PHX55397"/>
        <property type="gene ID" value="CP500_011020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="184" mass="21424" checksum="77250168631EC3F8" modified="2018-01-31" version="1">MSMKFNTVQEVTLWKNFIFNGEVYDLSHLNARWIEYVDKKDEKNIITYKFIVTYGLHCFTKDSDDISSEESQLLMYNGPRESRTFNFDRYQLSRQLPSIVESLGEKETLVCHAGYGKFAIVKIVDSNGIEVDYFVAFAAFRESKRLRLHIHSAYPIYEGIGKVEKVGFFVIAKKLLQNKELPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1T4</accession>
    <name>A0A2G4F1T4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CCA tRNA nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_009340</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55721">
        <property type="protein sequence ID" value="PHX55721"/>
        <property type="gene ID" value="CP500_009340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032810">
        <property type="entry name" value="CCA-adding_enz_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13735">
        <property type="entry name" value="tRNA_NucTran2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="5">
        <location>
            <begin position="25"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="6">
        <location>
            <begin position="162"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA_NucTran2_2" evidence="7">
        <location>
            <begin position="262"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="418" mass="46493" checksum="F80542A4D6A42993" modified="2018-01-31" version="1">MSINLLPTLSPDSWPFDLELLMPPAYLVGGAVRDALLGRRSHYFDLDFVMLTRAVKTARKIADRTNAGFVLLDAERQIARVVFAGGTVDLAQAEGGSLEGDLWRRDFRMNAIACNPFTGEIIDPVDGQTDLRLGLVRMISRANLEDDPLRLLRAYRQAAQLGFAIEPETLCAIRELAPLLSQIAVERVRSELGYLLSNPNGVPWICRGWEDGLFSIWFESAIDRFDTLTKIDASAANLAAIYPELGKEFGRQIRDTIKTPLLAVAKLAMLVDSDPTIAETQLLRLKYSNAEIKSAIELVKYLPKLQAQPISEMSLREQYFLFRDVGIVFPVLAVLAVAVEVSVDEISVLINRYLDANDIVAHPTQLVSGNDLMEHLNLPRSPRIGQLLMEIQLARVEGRISSREEALVLAKELVDKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F211</accession>
    <name>A0A2G4F211_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_008630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55813">
        <property type="protein sequence ID" value="PHX55813"/>
        <property type="gene ID" value="CP500_008630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="9"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_7C" evidence="3">
        <location>
            <begin position="148"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="426" mass="47865" checksum="E2D20C83399AF515" modified="2018-01-31" version="1">MNKENLTVSVIIPSHNRSSSLRRAIEALHSQTYPIDLMEVTVVADSCIDDTLAMLQEYKAPFKLHAIEVNCRSAAIARNTGAVAATGELLLFLDDDIEAMPLLVESHVRAHNERAGCAVMGPYPPKLQGGTRFFDVEVRAWWEEKFYQMSRSDHRFHYQDLLSGNLSLDAGLFARLGGFDVAFGNCGGEDYEFGLRLLKADVSFVLAAGAVGYHYEHETNNLDRSFRRSRQEGRSDVLIGQRHPELRPMLHIKDYETPYSLIDKILVAIAFFRPAVVDWLAMGARKSLDLLESLGMRETWRWLRAKLRGYWYFRGVIDELKSRSAISSFMQGGPARTDLGGHEINIDLYQGWEAAENLLDAERPTGVYLYYDQLTVGHILPQAGAEPLRGSHLRSILALHFAEPLARAIGANGMPRTAEKIEEKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F268</accession>
    <name>A0A2G4F268_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55835">
        <property type="protein sequence ID" value="PHX55835"/>
        <property type="gene ID" value="CP500_008765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="321" mass="36579" checksum="24A1B906E8865C41" modified="2018-01-31" version="1">MNTAKVSVIIPAFNAAKTLAEAVASAVNGSYQYLEILIVDDCSTDDTSKVAAKLAESDPRIQLFINPQNYGVSKSRNLMIDRATGEYVAFLDSDDTWEPNKLEFCLQMLAENPEVKAVAHALRYLDKSGNKLSYIATYPTTKAQMQAIKVTGESPWVFPSSVVVDRAILVKEGGFAEDWLVGEDTELFTKIAQKHGLLAATQPLGNYRIRENSLTDKHWLKKRIAADCVKENQRRRLQGEPELSLNEYEHLCFQDLPLWKRLNKFRKFLALHYMRKVGQSWLNREFLPTLVYGIVTTVLNPQASLNKLKWMKYHEERFDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2B7</accession>
    <name>A0A2G4F2B7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acetylglutamate kinase</fullName>
            <ecNumber evidence="7">2.7.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N-acetyl-L-glutamate 5-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">NAG kinase</fullName>
            <shortName evidence="7">NAGK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">argB</name>
        <name evidence="9" type="ORF">CP500_008305</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acetylglutamate kinase family. ArgB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55888">
        <property type="protein sequence ID" value="PHX55888"/>
        <property type="gene ID" value="CP500_008305"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04250">
        <property type="entry name" value="AAK_NAGK-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00082">
        <property type="entry name" value="ArgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037528">
        <property type="entry name" value="ArgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041727">
        <property type="entry name" value="NAGK-C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="33"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="72"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="299" mass="31644" checksum="191EEE00FAC1F223" modified="2018-01-31" version="1">MLKHSDFPRNVETNRVQVLSEALPYIQQFAGRTIVVKYGGAAMKDGSLKEKVIRDIVLLSCVGMRPVVVHGGGPEINIWLEKLGIEPQFKNGLRVTDAATMEVVEMVLVGKVNKEIVSLINQAGGKAVGLCGKDGNLIQARPDGREGIGFVGEVSGVKVQILESLVNSGYIPVVSSVAADENGQSYNINADTVAGEIAAALGAEKLILMTDTAGILEDYHQPDSLIVKLDIQEARQLIDSGIVSGGMIPKVNCCVRSLAQGVKAAHIIDGRLEHALLQEIFSDSGIGSMIVASGYGGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2F6</accession>
    <name>A0A2G4F2F6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55928">
        <property type="protein sequence ID" value="PHX55928"/>
        <property type="gene ID" value="CP500_008110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="14932" checksum="4F18816BFB9BFBB2" modified="2018-01-31" version="1">MEPLADFLTPEECAEVDMALLSSKEKFSARLAIYALRVLKQIAGETGLSVAQVSNQQVMDWVRNDESIKGSIELDASFENFFTNLVIASLRPLRQIAVESGGAIEQLTVKQVVGWFVKDGKIRREQGVDAAFLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2G9</accession>
    <name>A0A2G4F2G9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55973">
        <property type="protein sequence ID" value="PHX55973"/>
        <property type="gene ID" value="CP500_007975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045397">
        <property type="entry name" value="DUF6516"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20126">
        <property type="entry name" value="DUF6516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14894" checksum="74D981469D94F9E8" modified="2018-01-31" version="1">MISAQYITAIKAKFLSSLAVSYVAIVKERSLLESGYFRARLTLKNGDFLEVVEFFTVFDNRCITESYRYQWMDETQQTLRKRWDNVEHFPNLPNFPHHVHIGEESNVEPSSSMNILELIDLIEKHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2I2</accession>
    <name>A0A2G4F2I2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase III subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">holA</name>
        <name evidence="2" type="ORF">CP500_009730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55677">
        <property type="protein sequence ID" value="PHX55677"/>
        <property type="gene ID" value="CP500_009730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010372">
        <property type="entry name" value="DNA_pol3_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06144">
        <property type="entry name" value="DNA_pol3_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_pol3_delta" evidence="1">
        <location>
            <begin position="4"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="325" mass="36332" checksum="8A89DC9153B93BF4" modified="2018-01-31" version="1">MQIYFFWGEDDFAMGQAVTSLRQSAVDPNWASFNYDKIMADRAEAVVEGLDRALTPPFGTGSRFVWLANTTVAQQCSPELLAQLERTLPVIPDSTVLLLTSVKKPDSRLKSTKLLAKSAQVREFSPIPPWNDKELAQRVRQVAGEMGVKLTATAIEFLAESIGSDTRQLYSELEKLLLFAGNRTQPLTPEDVGKLVNSHAQNTFQLADAIRQGHTEEALDLLAGLTGRNEPGLRIVAGLTGKFRIWLWVKAMIESGDRDDKIAQTLDLGNPKRVYYFRQEVKNASLEKLQKTLPLLLELEASLKRGREEKSTLQTKVIELSSLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Q3</accession>
    <name>A0A2G4F2Q3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56029">
        <property type="protein sequence ID" value="PHX56029"/>
        <property type="gene ID" value="CP500_007705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="43"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="411" mass="44506" checksum="697423C2BDE230ED" modified="2018-01-31" version="1">MKVSLLPALNDANLDAAAPSSQRQLAISVSATTSDQDNRVPLNLCLILDHSGSMGGRPLETVKQAAGQLLDRLKPGDRFCAIAFDHKAKVLVPNQVVEDPASIKRLIEKLRPAGGTSIDEGIKLGIEELGKGKKEAISQAFLLTDGENEHGDNNRCLKLANLATEYNMTLNSLGFGDNWNQDILEKIADAGGGALAHIQRPEDAVEEFSKLFTRVQSVGLTNAYLLFSLMPKVRLAELKPIAQVAPDTIELPVQQEGDRFMVRLGDLMKDVERVVLANIYIGQLPEGQQAIGQLQIRYDDPAIGAGLLSEQVALSTNVMQVYQPAINPMVQQHILALAKYRQTQLAETRLQQGDRAGAATMLQTAAKTALQMGDQSAATVLQTSATRLQSGEELSEGDRKKTRIASKTVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2R3</accession>
    <name>A0A2G4F2R3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56039">
        <property type="protein sequence ID" value="PHX56039"/>
        <property type="gene ID" value="CP500_007765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="30869" checksum="0DBC80966821828B" modified="2018-01-31" version="1">MQITDTLIKSEYANDQLDVAERARLQELESIVENGLQIFYEVGKALDEIREQKLYRETHKSFEAYCREKWAIARRTADQFIGAARVIENLSAIALKIPTKENQVRPLAGLSPELQLEIWQEALKLSPNGMPTGAAVQRLVDQRFPSGVAGRTPKETDSELEKLRSDNKRLREEVRQQNRDRDRRAAAVALEMEQLRAENRQLKAELLQRDKDWEIRLAVERRKIREEVRAELKAEYEGQINSLTQQLAEMTANYQSVLARLTALEGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2V7</accession>
    <name>A0A2G4F2V7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_007150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56078">
        <property type="protein sequence ID" value="PHX56078"/>
        <property type="gene ID" value="CP500_007150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="14"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="414" mass="44525" checksum="FE2BED07F2456062" modified="2018-01-31" version="1">MNIFRDIEPQPRRNLLTLFATGLLFWSSLASLLPTLPLYVQFVGGTKQQIGFVMGAFAIGLLFSRPQLGKMADSKGRKQVLLLGTLVAAIAPLCYLFAKSIPLLLCIRAFHGISIAAFTTAYSALVTDLSPPGKRGELIGYMSLVSPIGLAFGPAMGGFLQAWVGYTPLFVMSASFATMAVLCTCQVTEPNFVESTKPDSSSNEKNGKNYWQMLWNPRVRIPALVLLVVGLVFGTLSTFMPLFVQETKADFNAGLFYSTAAIASFAIRLVTGRASDKYGRGLFISGGLICYCLSMLLLYNAQNTSSFLIAALVEGCAGGTVLPMMVTLMSDRCEPQERGRLFSLCIGGFDLGIAVAGPTLGFVAEQVGYRNMFGFAAGLASLALVIFVTQCSKDLSHSVRFAIGRGTDVYALNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F315</accession>
    <name>A0A2G4F315_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Precorrin-6Y C5,15-methyltransferase (Decarboxylating) subunit CbiT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cbiT</name>
        <name evidence="4" type="ORF">CP500_006810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56150">
        <property type="protein sequence ID" value="PHX56150"/>
        <property type="gene ID" value="CP500_006810"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014008">
        <property type="entry name" value="Cbl_synth_MTase_CbiT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02469">
        <property type="entry name" value="CbiT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="3">
        <location>
            <begin position="41"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="197" mass="21804" checksum="0C1D32EF666BEAB4" modified="2018-01-31" version="1">MLWPYVSPGIPDDLFERLPGIPMSKREVRLLLISHLRLQADSVVWDIGAGTGTIAVETGLLCPKGKIIAIERDEEVANLIRRNCDRFELNNVEVIEGSAPECLKNLSKPPHRVCIEGGRPIKAIVQEVWGYLQPHGRIVATAGNLENLYALSESFAELQVRNIEVVQSAVNRLETRGLSQTFAAVNPIFILSGEKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F325</accession>
    <name>A0A2G4F325_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY</fullName>
            <ecNumber evidence="5">2.4.1.255</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_006865</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:48908"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:12252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:90840"/>
            <dbReference type="EC" id="2.4.1.255"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.255" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56160">
        <property type="protein sequence ID" value="PHX56160"/>
        <property type="gene ID" value="CP500_006865"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-GlcNAc transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009740">
        <property type="term" value="P:gibberellic acid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037919">
        <property type="entry name" value="OGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366">
        <property type="entry name" value="PTHR44366"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0939">Gibberellin signaling pathway</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="114"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="308"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="342"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="376"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="412"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="446"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="480"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="514"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_41" evidence="12">
        <location>
            <begin position="903"/>
            <end position="1057"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX56160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1087" mass="122153" checksum="659D2CEBE594CA58" modified="2018-01-31" version="1">MIAESLVNLEAAQSYFQKANRLKETGRFDDAIAHYHKSLEFNREDADVYKRLAEAYALQGEFEKAIASCNLALKFNPNFAPTYLTMGNVLHSQNKLDMAIQAYLAALKIEPRFAEASANLGSMYYKLGQLAEAEKSYQIAISINPALCSVHSMLGSVLQHQGKLDAAIACYQKVLELQPGDVSTAKKLSDLVKQKDGETSQNKFIELEAESAEPQTVSVNKDEGYGLQPSSINLQPADRTENLNTPFTNPAEVSEPVSQLNIPNSEQTASFKEVEHYKSLAEDCLVQGKIQEAIAACHLAIKTRPDYIHAYVTLGNALQAGGKIEAAIRSYSQALELQPNFAEVRANIGSMYFKMGRLPEAIAYYQEAIALCPNLAGAHWNLGKVYHKNGNVEAAIACFQRTSELNPQLVGADFHFNLGNRLFTEGKRDEAIDSYSKAIAIKPDWAEAYANIASARSQQGDLDAAITYYQKAVDLKPELEVLHSNLANSFLQQGKYESAIASYQSALKIKPDWADVHANLGNAFSMLGQLAEAQASYQEALVFKPNWAEVYCRMGHIQKQDKPLEAIANFEKAIELNPKFSEAHQQLCDLLSHSTNLARARRVADKYCEHCGEEVPVMSATAYVFSYLQSGVSEQAIQKLEEIEKLCYQKVETFTNMELKLLYEIFLFAVSHLRDNRDKNASFYRLVAKEYYKKVLPPRQLVNRIKPVNYQTNQKPLRIGFLSKHFRRHSVGWCSEALIRELSRITPHVHLYVTGKLNKDEVTQRFEDMAGKFYWPKKYPNGFADGGEILAEVRQDDLDVLIDLDSMTVPTNVEVLHQYPAGICVSWLGFDAPYISENHYFLCDEHTHPAGVDKHYLEQLVRLPSCSVAIGALQSISVDRNAIRNSLGIGLNQMTYLCVAPGRKTNPEMVRAQVKILKEVPDSLLIRKGQGDPDIIHSTYREECAIQGVDFSRIKFVGQTKTEEEHRAIYYVADVLLDSYPYNGGTHNLEALWANLPVVTRSGDQYLSRMGYAFLKSANLDVGAAWTWEEYTQWGVKFGRDASFRNAVKEHLIKSKRPEHLAPLWNPQKLAREMYEVFQQLLAVDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3I2</accession>
    <name>A0A2G4F3I2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fructose-1,6-bisphosphatase class 1</fullName>
            <shortName evidence="7">FBPase class 1</shortName>
            <ecNumber evidence="7">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fbp</name>
        <name evidence="11" type="ORF">CP500_007755</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the FBPase class 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56037">
        <property type="protein sequence ID" value="PHX56037"/>
        <property type="gene ID" value="CP500_007755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="PTHR11556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FBPase" evidence="9">
        <location>
            <begin position="26"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="FBPase_C" evidence="10">
        <location>
            <begin position="220"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="138"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="352" mass="38721" checksum="9D6123D085D4C1A7" modified="2018-01-31" version="1">MVHAPIGETRLGPIDQVQSLDRDCTTLSRHVLQQLQSFSADAQDLSALMSRIGLAAKLIARRLSRAGLMEDALGFTGAVNVQGESVKKMDIYANEVFISVFQQSGLVCRLASEEMEKPYYIPENCPIGRYSLLYDPIDGSSNLDINLNVGSIFSIRKQEGDDADGSASDLLQHGHKQIAAGYVLYGPSTMLVYSIGQGVHSFTLDPSLGEFILSTENIKIPDSGQIYSVNEGSFWQWEEPFRDYIRYVHRSEGYTARYGGALVGDFHRILFQGGVFLYPGTVKNPDGKLRLLYESAPLAFLMEQAGGRASTGIQDILDVVPTKIHERTPLIIGSKENVALVESFIKASIAQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3I4</accession>
    <name>A0A2G4F3I4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56295">
        <property type="protein sequence ID" value="PHX56295"/>
        <property type="gene ID" value="CP500_006070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="344" mass="38091" checksum="A4D3D1CA6AC31ECB" modified="2018-01-31" version="1">MGNQNLRLIQNFFQVAKPRLKPYLRYCILGGTFLFIAQAFLTHWREIANIRITAESFPLLAIALGITLFSMIFAGWVWMLILREFRQRVNAAWAIQVFLKTNIAKYLPGNIWHFWGRISDAKKAGILPKVATLSVLLEPLLMASAGVLIGLISFDKIHWFLRFVGCAAILTAIHPQTLNPIVLFVEKLKLKKQDGEISKAEGDRLILRLESTSSLAKITSSVKSKRKINLPIKRYPLLPLIGQMCFIGLRGSGFVLTVMALNPVNFNDIPNLFGAFCLAFVVGLVVPGAPGGMGVFEATAIALLDDRYSTGIILGAVALYRIISILADVSGAALAKIDRKRDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3K7</accession>
    <name>A0A2G4F3K7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56339">
        <property type="protein sequence ID" value="PHX56339"/>
        <property type="gene ID" value="CP500_006020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="150" mass="17814" checksum="539277E947F3BDB1" modified="2018-01-31" version="1">MKIRCIAKTGESLPEKYIDPPRGYTRKVELPLTIGKEYVVYAIREWKGTIWYYICNDNYSYYPIHNPAPMFEVVDSRVSKYWRFELSPNGLLMIAFEQWFTDPYFYDKLTDQEEAEVEIFDQVKELMDAEDFDLPPLDVAVEKLRETVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Q3</accession>
    <name>A0A2G4F3Q3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56351">
        <property type="protein sequence ID" value="PHX56351"/>
        <property type="gene ID" value="CP500_005770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="5"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="208"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="424"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="686" mass="77997" checksum="190B3A65B04AD20A" modified="2018-01-31" version="1">MKLISITLCNFRQFYGSTPEIKLAYGERNITVIHGNNGAGKTALMNAFTWGLYENLSGFAEEQLVNKRAIAEAKPGKRVPCWVEIVFEHDSKRYRVRRSRDAYKSQNSVEHSKSELFMQVAKDDGRWMLPPQHPDDIIGRILPESLHQYFFFDGERIEQIVRHDKKAEIAEATKELLGVEVLNRSIRHLGDARKSLETDLRMIGSSEVKKLLKDKQKFEKEVEQFLEKQVEIEQELIHQGELRKAVNGDLLQLGGAAELQKLRDELEKQRHLFKQQIVQATDAIKRAISVRGYAVFLSDAAAEFEVILGGLREKGELLSGIQQPFLEGLLAQQRCICGAELVEGSEARENVSGWMDKAGVGDVEEATIRISSRVNEIDRQVADFWEEIDRQQANISHDRDELYKVETQLEDIHNKLRNFPDTDVSGLQKRLDEIEAKIGDLHRESGSNQQQIESLRVQVAALDKQIDKQQLNEERQVLAQRRISATQGAIDRLTEVRSRLEKQFCSQLEQRVQNIFSQISFTPYIPKLSDKYELTLVENTSGKEALVAASTGENQILSLSFIGGIIDGVREWSQKNTLMGPDSSTFPIVMDSPFGSLDEIYRKQIANKLPKLANQLIVLVTKTQWRGEVAQEMESCTGREYVLVYNSPKADCEEDAIELGGTCYALVKQSPNEFEYTEIVEVDYGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3S2</accession>
    <name>A0A2G4F3S2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome partitioning protein ParB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56371">
        <property type="protein sequence ID" value="PHX56371"/>
        <property type="gene ID" value="CP500_005880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="2">
        <location>
            <begin position="16"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="237" mass="27052" checksum="18FD7F9AB3E8B996" modified="2018-01-31" version="1">MKKLFPSLVAVKRITSAVPRSNFAEADLERLARLILESGGLINPIIVRRNGMDAYEIVDGDFEYYAAARAKEIEPLKGETIGAFILEEENEKLLLEQLEIHRKTAIIDNPSANKVPQQSSSFEQRLTNIETRLENRINELKAEYTREKQALIERVKDVESRIPKPVPLLEALNTQDKFKLATNLKNAGIKAQIIEQIIKQRDLEPFASFENVLERMKGKGLGDKTMIKLIDKWQKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3S3</accession>
    <name>A0A2G4F3S3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56396">
        <property type="protein sequence ID" value="PHX56396"/>
        <property type="gene ID" value="CP500_005645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="10972" checksum="99BF1F87CADD8507" modified="2018-01-31" version="1">MSSGNILTVTDVLNFLVSGIDKTTLETELTTSGWISTPARGGSKSGAGTIWTSPDTQYSVRIMTQPTGSSYARVYNGPGGGAPAEQPLNASGKPGSRADTHFILLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Y0</accession>
    <name>A0A2G4F3Y0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="5">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsY</name>
        <name evidence="8" type="ORF">CP500_005100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56470">
        <property type="protein sequence ID" value="PHX56470"/>
        <property type="gene ID" value="CP500_005100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="7">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="8"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="371"/>
            <end position="378"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="454"/>
            <end position="458"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="518"/>
            <end position="521"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="569" mass="61444" checksum="8FF1CEF4E7622A20" modified="2018-01-31" version="1">MVFNWFRRQYSESGSSEQETPEQPQEDLPTESAPVEAQTDAADPSSPAIAEDYLNWAKAAYKNIQKQQKPETEITETPATEVPAAETDVAESDAVEVPDAIAIPEPLAQVVTEISEISEPVIVETTDAESIAIVEPITQQLEVSTETREIAEPAISVADSASMESDGETATTEVEAEPTESLPFWARAQADRLERIERLKETAIEEPEVIAAAAARAAIIEEIPGFAFDEGFLWSSEILASQGRRPDQVSVEEITWLQKLRKGLERTRRSLINRLKAIVGQGPLNQDAVAEIETLLLQADVGVAATDIIISRLQARLREEVLPPEEALAYLKTILRDILDAPCSESAIGNPAYSLTFAPEKDTFNIWLIVGVNGAGKTTTIGKLAHIAQKSGYKTLIGAADTFRAAAVEQVKVWGARSGVEIIANPGKNTDPAAVVFDAIAAAQARGTELLIVDTAGRLQNKKNLMDELSKIRRIIDKKAPGATVESLLVLDATLGQNGLRQAEVFAEAAKLSGVVLTKLDGSAKGGVALAVVQQLGLPIRFIGVGESIEDLRPFSSYEFVEALLDFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F420</accession>
    <name>A0A2G4F420_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56510">
        <property type="protein sequence ID" value="PHX56510"/>
        <property type="gene ID" value="CP500_004965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="181" mass="20882" checksum="3A799AFF5F82287B" modified="2018-01-31" version="1">MLDENLEIETPIDVDIIALDKDDRVVVLIEVKIIQAQEPAAKQRIADYMISWMKAVLAKISEQRTIIPYAMFVDTEQILIFKWDGVNLSEPVCSLNTGEILRHYEPEFGKKWISERYLESLIESWLRDLAYNWKSEMPPASEQIAIIGLLQRLASGTTKAGVQLGHFVYRDKLLDEYCHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4B2</accession>
    <name>A0A2G4F4B2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56586">
        <property type="protein sequence ID" value="PHX56586"/>
        <property type="gene ID" value="CP500_004770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008884">
        <property type="entry name" value="TylF_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40036">
        <property type="entry name" value="PTHR40036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05711">
        <property type="entry name" value="TylF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="541" mass="61032" checksum="D503C010514DAF97" modified="2018-01-31" version="1">MTWCTNGFLKKVKESSSLGDPFLNKLFHYVEEYQPVSQVGSSVDLSGDRQKFTQLIQKGKECFVKGEIETAIATFTQALKVHPSSLIAQNYLSSLYWQVGDVQKSLQHHIQAQFSNIAFHKTLTDEFQEILSVIRPYTLLSEARLFSLYSLARQICLDNIPGNFVECGSYKGGSAALLAVVIKRYSLRPRLLYAFDTFEGMPEPTEADKHHGIPANLTGWVAGTLKAPLTDNLDVICQSLDVADIVIPVKWLFAQTLPESKSAIGSIALLHADGDWYESTMDIFKNIYDRVVPNGFIQIDDYGHWDGCNKAIHEFERRCGESFALRVIDYTGVWFQKEDSVHQDCNHWRTFWHLAQASEKLGNIELAKKAAQAVLKIMPKLVKAENLLNRDRSQLELVVSPEVSLSAELDDFLNNLRLREINIILFPDWQQPEESLCLQLEGVITLLFAQKDPSKITALLDTSNISEEDANLVLSSVIMSILMQQDLDETDVPEVSLLGNLTEIHWKALLPCINYRVVLENENQQAVIQAGAENLPVWEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4V3</accession>
    <name>A0A2G4F4V3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56814">
        <property type="protein sequence ID" value="PHX56814"/>
        <property type="gene ID" value="CP500_003420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15710" checksum="20AE4B8C45244658" modified="2018-01-31" version="1">MTPEELFKDGFDRYQAGEAPKDLIPVFKEVCLKAPKNGNAWASLAWLYLLEDKPSSAQKAAKTAVKLNPHDPQARINLAIAILDLKEKGVRPHVEVTQQLLMASEELLEEVKKNFEDGLSRKPDWKSLTRIQQWLFEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Z0</accession>
    <name>A0A2G4F4Z0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56816">
        <property type="protein sequence ID" value="PHX56816"/>
        <property type="gene ID" value="CP500_003510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7163" checksum="E949DB3C6022C2AD" modified="2018-01-31" version="1">MFYEDAIPQGFSQTFLDSLTRFDATICVITHSPHPTIPTFSPQEPHMIQTIINWLQRTVLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F509</accession>
    <name>A0A2G4F509_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1822 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56828">
        <property type="protein sequence ID" value="PHX56828"/>
        <property type="gene ID" value="CP500_003255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014951">
        <property type="entry name" value="DUF1822"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08852">
        <property type="entry name" value="DUF1822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="496" mass="55335" checksum="B14210CFD56BBC42" modified="2018-01-31" version="1">MFDLTKLQLVDSSDSCLVRLTIDQADQETAWHQAQDHSNPISRYNAYLNGVCLKTFMQWITELLAEEGLPQPSVWKRQDIASIWEFVNGTAIEIGDTRLVLIPSDQGDLEELFVPQEWVDMPNWTADYYLSVQVNLDGDDDEESWMEVLGFATHRQLKHEGRYNAGDRTYALSTQELTKSLLVMDITLGLNLQQKVPPLPSLSELESTELLHTLGNLSVYSPRLLVPFAQWASFLNNDECRQELYNQRLGIIEEPVLAAAPSVVVQSEANLVERLNTYIQAGWEAIDDIVERFGILDSGFMYAMEGGGYRYGGSSSQKGIPTLLDLLQSRNKSNQLRAAELLGGVGVGNQEAISALTQLLQTTQDDNDILKRQAALSLGKLDPKNSAAGVRIGKIMELTIQLDTVHVVLQITLLPQGTDKTNIELRVLPVPSTTSKTLPPNLELIILDEEGEVFWKEKAQNSRKNIPNYEFTAAVGDCFQVKVACDGFSITEDFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F528</accession>
    <name>A0A2G4F528_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56894">
        <property type="protein sequence ID" value="PHX56894"/>
        <property type="gene ID" value="CP500_003160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="25"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="198" mass="22966" checksum="BD824121B1A304DD" modified="2018-01-31" version="1">MTAQLLEEIGTLGEQRFVLPSYYSWEQFEALESLMADSSGLRITYLDGWIEFMTLGEAHESFKKAIAILLEAYFCEFGITFFPVGSATRRNRAKDVSFEPDESYYIGKKKEHPDLAVEVTITSGSTNKLAKYLRLRIPEVWFWENNQLSVYGLREDNYEQVSRSELLPELDLELLVRCVLMPSIIEARQEFIKGIRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F580</accession>
    <name>A0A2G4F580_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56963">
        <property type="protein sequence ID" value="PHX56963"/>
        <property type="gene ID" value="CP500_002435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="277" mass="31535" checksum="CAE1D2EE342F401B" modified="2018-01-31" version="1">MGIKEECDVLQSMLSQVIDGLAEVQSRAKSLPDCDIYELKREISDILEICCEEMLRLKNSQKQIELIQTMIGVQSFLPSIIYPTISLANTYADTSIITSIITDLKKNPLVYKTLPWLKMLGDAGELAVWKVLLDVDSEDNLDWSEVQIKPKLEYDPAKKPAEPDFYITSSQLICDAKAWKPADIYQGKKSSVEINPQSLKNAASKYARCLKDGGEVRLYFPEDTYNQQKPLLDLLSLEVQSEFSNVKINMLPMPGVTYQDLSRQTRFRYTFLKWLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5E3</accession>
    <name>A0A2G4F5E3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_002415</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56959">
        <property type="protein sequence ID" value="PHX56959"/>
        <property type="gene ID" value="CP500_002415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021147">
        <property type="entry name" value="DUF697"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05128">
        <property type="entry name" value="DUF697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="4">
        <location>
            <begin position="29"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="393" mass="42950" checksum="E4229B5EE4B761CF" modified="2018-01-31" version="1">MSDDFSLDDLLIKSYDAFKDAENDVGQCNVLVIGKTGVGKSTLINAVFRQRLAETGVGRPVTHGIRQYTKPNCPIAVYDTPGLELNAEQIKIIQLNVAKLIEDQRLLHPKEHIHVIWYCINHGANRIESVEESWLREMEIMDVPVILVLTQTTSKKPSEFFKQLEHMNLPVSQVIPVMAEPEEIDEDYTVKSHGLDKLVDATFQLLPEVAKKAFVKEQIANIGLKSDMAFKYLSAYVAGSAIIGATPVPFADAPILMTMQTAMIANITVIFGMPFDKGFISAMLSAISGAGGVTAVGRSIVTNLIKMIPGAGTIVGGAISGATAATLTLALGLAYIEVLKVYMKSQINGEKLSLPQLTKMFVDLYKDYASSGRKTLKDDNRNQPKPPNQINID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5E5</accession>
    <name>A0A2G4F5E5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP synthase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_002525</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56980">
        <property type="protein sequence ID" value="PHX56980"/>
        <property type="gene ID" value="CP500_002525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005598">
        <property type="entry name" value="ATP_synth_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03899">
        <property type="entry name" value="ATP-synt_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="150" mass="16723" checksum="8F58A94E6B3F055B" modified="2018-01-31" version="1">MNTPNTPTQPAPATEDLPQTGTVSTVSSETGNSMQDFYRLQQELLVYTLAFTGIIFISVWIFYSLNIALNYLLGAIAGVVYLKMLARDVERIGSQNQKISKTRLGLLIGLMIVAARLDQLQILPIFLGFLTYKISLMIYVLRSALAPDYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5I3</accession>
    <name>A0A2G4F5I3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfate transport system permease protein CysT</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysT</name>
        <name evidence="11" type="ORF">CP500_003760</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56737">
        <property type="protein sequence ID" value="PHX56737"/>
        <property type="gene ID" value="CP500_003760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015419">
        <property type="term" value="F:ABC-type sulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011865">
        <property type="entry name" value="CysT_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005667">
        <property type="entry name" value="Sulph_transpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406">
        <property type="entry name" value="PTHR30406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406:SF8">
        <property type="entry name" value="PTHR30406:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00969">
        <property type="entry name" value="3a0106s02"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02139">
        <property type="entry name" value="permease_CysT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0764">Sulfate transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="71"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="31142" checksum="AEEA3C9358B30731" modified="2018-01-31" version="1">MTVSSPINNPQSPIQNIKRAIGKITLPWGITLGYLSLMLLLPVAAMLLKASTANPAEFWKIATSPIALSAYDVTFFTALIAALINGLFGTLIAWVLVRYDFPLKRIVDAIVDLPFALPTSVAGLTLATVYSDNGWIGSLFAPLGIKISFTRLGVGIAMIFISLPFIVRTVQPVLNEMEKDIEEAAWCLGASQFQTFWRVVLPPLFPSILTGVALGFSRAVGEYGSTVIVASNIPFKDLIAPVLIFQRLEQYDYAGATVIGTVMLAISLAMLFAINLLQAWRRRYDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5J0</accession>
    <name>A0A2G4F5J0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpB</name>
        <name evidence="11" type="synonym">atpI</name>
        <name evidence="13" type="ORF">CP500_002520</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cellular thylakoid membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX57008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57008">
        <property type="protein sequence ID" value="PHX57008"/>
        <property type="gene ID" value="CP500_002520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045082">
        <property type="entry name" value="ATP_syn_F0_a_bact/chloroplast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42823">
        <property type="entry name" value="PTHR42823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX57008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="250" mass="27707" checksum="F0EB7D5DA31A7AE8" modified="2018-01-31" version="1">MLDVLNTFNRFPLAKLEVGQQLYWQLGNLKVHGQVFITSWFVIAVLVVVSLLGSSKIQRIPSGMQNLMEYALEFIRDLAKNQIGEKEYRPWVPFIGTLFLFIFVSNWSGALIPWKLIKLPSGELGAPTADINTTIAFALLTSLAYFYAGLSKSGLGYFAHYVEPVPFMLPFKIIEDFTKPLSLSFRLFGNILADELVVGVLVLLVPLFVPLPVMVLGLFTSAIQALIFATLAAAYIGEALEGGHGEEHHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5K4</accession>
    <name>A0A2G4F5K4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57052">
        <property type="protein sequence ID" value="PHX57052"/>
        <property type="gene ID" value="CP500_002350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="123" mass="14212" checksum="DC0639C23D29D353" modified="2018-01-31" version="1">MEHSSEIAKDFDNLIASFNQIKGLYAVESPVETFQIIIEQEAIALLILEAHSKIRELFPTERLGLEVKTDPEIANWRSLWITIYTKLEVEEAFAKLKTLDRTWWLDASLVVPNNILNIDLGWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F612</accession>
    <name>A0A2G4F612_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57179">
        <property type="protein sequence ID" value="PHX57179"/>
        <property type="gene ID" value="CP500_001240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013834791" evidence="2">
        <location>
            <begin position="30"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="371" mass="37845" checksum="48BEC09FA51C662E" modified="2018-01-31" version="1">MNNLFSKSTFALVNLVALAVCCTALSVKAETGNLSDVATTASLQSQNLARLSDTAATKSPEANVEATANTQIDSISALELDPAVQSGLAAEPVASQPAANSQASVVAPEKSDVANSEITATENISIGAETKNSEAVPTIADGSVKVQPSVEIAADRDRPTSTVANGDNSELTAANTEKEVKTAKEVLSNPVSTSASALTNEPTTVAKSETTSAPTQKVAQDNKVRPGRSTRSGPSYIGIGGNLGFGGDTALGDTSFAIISKIGLTSNFSVRPTVLFRDNVTVLIPVTYDFGSQNAVEVSDDFVITAAPYAGAGVAFSTGDNSRFGFLISGGVDVPLSSNFTATAGLNIGFLDGAEVGLLLGVGYTFPNIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F629</accession>
    <name>A0A2G4F629_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57244">
        <property type="protein sequence ID" value="PHX57244"/>
        <property type="gene ID" value="CP500_000970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8271" checksum="136CDFD167865330" modified="2018-01-31" version="1">MNRQDACSTKIKFLVEQASCLLLLMNRQDACSTKIKFLVEQASCLLLLMNRQDACSTKIKFLVEQASCLLLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6E9</accession>
    <name>A0A2G4F6E9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57328">
        <property type="protein sequence ID" value="PHX57328"/>
        <property type="gene ID" value="CP500_000680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="92" mass="10356" checksum="9F14E952641CB221" modified="2018-01-31" version="1">MFWILKNLISTDPQGCLSLNLEPKSTEYRVLINEAGQILLDPITNIPDREQWLWQNPQALAAVKCGLAQAAKGEVHDLGDFSEYADLEIEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUG4</accession>
    <name>A0A2G4EUG4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000249">
        <property type="protein sequence ID" value="PHX53183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53183">
        <property type="protein sequence ID" value="PHX53183"/>
        <property type="gene ID" value="CP500_022855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="SSF50199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013922126" evidence="1">
        <location>
            <begin position="23"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="2">
        <location>
            <begin position="25"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="19744" checksum="C80ADC9B8AF9A711" modified="2018-01-31" version="1">MFLYRLLSIALCLLLASCQKPVIPTGTLVQVQRTVTGQTIEIITTVDQIALLEQIRLIGIEVPDLKQQPWGEAAKNKLEQLIGGKQVLLELDVEEKDGFDRKLAYLWQNQVLVNEQLVKEGYALATVRSRNTKYHQRLVNAQEWARLMGKGIWNPKQPLRQTPAEFRRQNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUJ2</accession>
    <name>A0A2G4EUJ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000242">
        <property type="protein sequence ID" value="PHX53209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53209">
        <property type="protein sequence ID" value="PHX53209"/>
        <property type="gene ID" value="CP500_022725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="199" mass="20293" checksum="347529AF8FCE07C8" modified="2018-01-31" version="1" fragment="single">MARLDGTTQDDQLIWEQPEPVELYGYAGDDTLWGDAGNDFIYGGAGSDYLLGDPGNDVISGGRDSDYIEGGLGADQLFGGKGADYLVGGGDTDTLIGGGGSDTFGLTSDGLAIIRDFDAGSDSIELLDDLTGSRVLVARNDSNSVGVYVSSNGGSSFDKALALLTNFTGDVGSVSRKIIGGNVTATPTPIPTPTPTPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUR9</accession>
    <name>A0A2G4EUR9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000221">
        <property type="protein sequence ID" value="PHX53292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53292">
        <property type="protein sequence ID" value="PHX53292"/>
        <property type="gene ID" value="CP500_022260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="PTHR30615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004681">
        <property type="entry name" value="UCP004681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="SSF111038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15448" checksum="E1AE47E38C9327F1" modified="2018-01-31" version="1">MTHYQQIFTIKTTGKSLCKITDQVENVVANSGIKTGLCTLFLRHTSASLLIQENADPDVLKDLANFLAKLVPEGATYIHDTEGPDDMPAHIRTALTHTSEQIPIAHHRLLLGTWQGIYLWEHRQRGQIRELVVHISGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUS3</accession>
    <name>A0A2G4EUS3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_022590</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000234">
        <property type="protein sequence ID" value="PHX53238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53238">
        <property type="protein sequence ID" value="PHX53238"/>
        <property type="gene ID" value="CP500_022590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040582">
        <property type="entry name" value="OB_MalK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005116">
        <property type="entry name" value="Transp-assoc_OB_typ1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17912">
        <property type="entry name" value="OB_MalK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03459">
        <property type="entry name" value="TOBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="4"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="60"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="441" mass="49371" checksum="972286D056044773" modified="2018-01-31" version="1">MAKVVLENIYKSFPLRPGEPEKEANTAENASPDSSHSTSNTVLRRINLTIEDGEFMVLVGPSGCGKSTLLRSIAGLEALTAGNIWVGDRLVNDLPPKDRDIAMVFQNYALYPHLTVYDNLAFGLRRSERGKKEEGRGKKEEEIINKNNSWVFMDSLIPIIRPLLEDLLVGLTRNLPKGLRYFSEREKAVGGRVMKVAQLLQIESLLNRLPKQLSGGQKQRVALGRAMARNPEVFLMDEPLSNLDAKLRGETRSQIVQLQRQLGTTTIYVTHDQTEAMTMGDRIAIMNGGQVQQVAQPLELYNRPANLFVAEFIGSPPMNFLPVQFTAPLLISHPQFRFTLPDIWAKTLRKYDGKSLILGIRPEHLTIHPPATKNLSVQVDVVEALGHETYLQVSLTDAPAVRLQVRVPPERSIRVGEELWLAIAHEKIHLFDPDTELAIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUT3</accession>
    <name>A0A2G4EUT3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">VKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_022245</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VKOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000220">
        <property type="protein sequence ID" value="PHX53299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53299">
        <property type="protein sequence ID" value="PHX53299"/>
        <property type="gene ID" value="CP500_022245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12916">
        <property type="entry name" value="VKOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012932">
        <property type="entry name" value="VKOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044698">
        <property type="entry name" value="VKOR/LTO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038354">
        <property type="entry name" value="VKOR_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07884">
        <property type="entry name" value="VKOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00756">
        <property type="entry name" value="VKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="VKc" evidence="11">
        <location>
            <begin position="11"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="307" mass="33782" checksum="61740AF0450E8D74" modified="2018-01-31" version="1">MIRRRSTPWIHRWSRTIMAAIAVIGVLETAYLTIAKFTTGSVICPTSGCDKVLNSPYATVFGVVPLSLLGCLAYLSIAILAFAPKSVNPDTNKGLYSQLENRTWQLLFVITAAMVIFSSYLMYLMAFEIQELCIYCISSAVFSLSLFVLVLVGREWEDLGQLVFTGILVAMVSSIAALGLYNSIKAPVTVSTPGIVPPLVTTTSSPAEIALARYLTQIGAKEYGAYWCPHCHDQKMLFGREAAKLINYFECDPKGQNSRAEICQATATNIKGFPTWEIKGQFYSGTQSLEKLAEFSGYSGPRNFINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUY2</accession>
    <name>A0A2G4EUY2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53341">
        <property type="protein sequence ID" value="PHX53341"/>
        <property type="gene ID" value="CP500_022065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="46"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="204" mass="22660" checksum="12A754875FD55C60" modified="2018-01-31" version="1">MDKREEVTIAEYELTAESFRVGTWHHDVSQNRDALTAAMPRKPGKILDIGCGPGRDLVAFKSQGHTVVGLDATPAFVQIAKELSGCEVLQQSFLNLDLPKAEFDGIFANASLIHVPSDEMVKVLKDLHKALVINGAIVMSMCRGNWEGYDERPTGKRYTAGWEYETLAPELQQAGFEIVNHYYRPPGLPREAQSWVVMVGKKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUY7</accession>
    <name>A0A2G4EUY7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ferredoxin--nitrite reductase</fullName>
            <ecNumber evidence="4">1.7.7.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nirA</name>
        <name evidence="4" type="ORF">CP500_021995</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.7.1" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000211">
        <property type="protein sequence ID" value="PHX53345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53345">
        <property type="protein sequence ID" value="PHX53345"/>
        <property type="gene ID" value="CP500_021995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048307">
        <property type="term" value="F:ferredoxin-nitrite reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012798">
        <property type="entry name" value="Cbl_synth_CobG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02435">
        <property type="entry name" value="CobG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="3">
        <location>
            <begin position="541"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="624" mass="68719" checksum="1B26F4D794368BD3" modified="2018-01-31" version="1">MTQTVEPQVSLNKFEKLKAEKDGLALKAELDNFAEIGWEAMDATDREHRLKWLGIFFRPVTPGKFMMRLRLPNGIITSNQTRTLAEIVQRYGDDGSADITTRQNLQLRGIRIEDLPDIFRRLKEVDLTSIQSGMDNVRNVTGSPVAGLDADELFDTRELAIEVQDMITNKGEGNPEFSNLPRKFNIAIAGCRDNSVHAEINDIAFVPAYTDGNIGFNVLVGGFFSAKRCEAAIPLNVWASPSDVVDLCKAILIVYRDRGPRVNRQKSRLMWLIDELGIEQFRAEVEQELGRALLPSAAKDEIIWDKRDHIGIYDQKQSGLKYVGLHVPVGRLSAADLFDLARIADVYGSSELRLTVEENVIIPNVPESRIELLLKEPLLERFSIDPAPLTRALVSCTGSNFCNFALIETKSRSVAMIKELEAELSIPKPVRIHWTGCPNSCAQPQVADIGFMGTKVRKNGKTLEGVDIYMGGTVGKDAHLGTCVQKSIPCEDLKPVLRQLLVDNFGAVPKTSGDIGSLNRQLLLTVDDSETILPTAKPLTSTVIFARSGKEVACSEDEFILDVAERAGVELDSNCRSGNCGTCKQKLLEGDIAYDGELDALKDIESGFILTCSARAIGKVAIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV15</accession>
    <name>A0A2G4EV15_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycogen phosphorylase</fullName>
            <ecNumber evidence="4">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_021840</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000207">
        <property type="protein sequence ID" value="PHX53371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53371">
        <property type="protein sequence ID" value="PHX53371"/>
        <property type="gene ID" value="CP500_021840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102250">
        <property type="term" value="F:linear malto-oligosaccharide phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102499">
        <property type="term" value="F:SHG alpha-glucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011834">
        <property type="entry name" value="Agluc_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024517">
        <property type="entry name" value="Glycogen_phosphorylase_DUF3417"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035090">
        <property type="entry name" value="Pyridoxal_P_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11897">
        <property type="entry name" value="DUF3417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02094">
        <property type="entry name" value="more_P_ylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00102">
        <property type="entry name" value="PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF3417" evidence="11">
        <location>
            <begin position="13"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="852" mass="97433" checksum="7F3541E28BF4239C" modified="2018-01-31" version="1">MQPIRTFNVSPSLPTILEPLRKLAYNLHWDWNVETKDLFRRLDRDLWDSSNQNPVLMLGTISQERLQEMAEDTGFIAQMNRSAQQLDDYLNNRAWYRKQRGTEQQECYAYFSMEFGLVKALPIYSGGLGVLAGDHLKSASDLGLPLVGIGLLYQEGYFSQYLNADGWQQERYPLNDFYNMPLHLERNPDGSELRIEVDYPGRKVYARIWRVQVGTVPLYLMDTNIEPNSRYDQDITDQLYGGDKTLRMHQEIMLGIGGVKMMKALGLTVTAYHMNEGHAAFMALERIRMLMEEHHLTFVEAEQVVVSSSMFTTHTPVPAGFDLFEPNMVMYYLGQYPKIFGLSQEEFLGLGRENTGDSSAPLNMAILAIKMSSFVNGVAALHGEVSRPMFGGLWPGLPQEEVPITSITNGVHARSCVAKSTQELYDRYLGPDWEMTASDDRLWDKMASIPDEELWRNHERCRSELVVFAREWLQKTLRERGAAQGEIENAREALDPKVLTIGFARRFATYKRATLFLRDVDRIMRIMRDKNRPVQFVIAGKAHPMDIPGKELIRDIVHFIREHETLNSMVFLPNYDINVARMMVSGCDVWLNTPRRPREASGTSGMKASMNGLPNLSILDGWWDEADYVRTGWPIGHGEFYEDTKYQDDVEANALYELMEKEVVPLFYHRDSDGIPRGWTAKMKDSIRLNCPLFNTTRMVKEYARRAYFPVSDRFHTMTEDNCAPAKDLSHWKKNLLSKWRDIKIEAVDISQDKEVKVNQSIDVKARINLMGLTAADVQVELYQGSIDVNGDIIGGVPMVMEYLGEDAHKVSLYKADITYTSSGLQGLSLRVLPKHENLSSPYEAGVILWAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV19</accession>
    <name>A0A2G4EV19_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polysaccharide export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_022225</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000219">
        <property type="protein sequence ID" value="PHX53306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53306">
        <property type="protein sequence ID" value="PHX53306"/>
        <property type="gene ID" value="CP500_022225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="4">
        <location>
            <begin position="162"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="4">
        <location>
            <begin position="271"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="508" mass="55570" checksum="BEF2B162374D3F9C" modified="2018-01-31" version="1">MNYQDFKMNKNNYVAFSLAGLYSTAWTLSFTALLWGLNDQVFPQKSLAQPVIPSSELLDRPPEPLPTSRPAKPNRGINPAFRNRPYRLGAGDQISIQVQRFPELNFTGAISPEGIIVLPLIGTVNVRGLTVEEARERLRERFTQFIKNPQVFASLLVQRPVVVTVTGEVARPGFYPLQTPQLPAALAAASGTTPTAELRAIRVRRTLPSGAVAEQIVDILTPLQTGIAPPDLRLEDGDAIVVPYQQATPDRKSDQDLASKYSLAAATTPVQVTVTGEVSKPGFYTLPIGTGRISAALVAAGGVTGKADLRAVRVRRTLANGRSVEEPIDLYTPLARARDLFDFPLASGDAIIIPELDATTKNLDYDRTLVSRSTLIKPRIYVRVLSYASGVLTSFYIENGSSFLDALNNLPVNLANLRHIALIRFDQKEGKAVNRSIDAKAALEGNLSQNPTLQDNDVIVIGRNLVERVGFAINSFTRPFRDILGFILFFEQLRNGVNNLFVPTNNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV80</accession>
    <name>A0A2G4EV80_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53439">
        <property type="protein sequence ID" value="PHX53439"/>
        <property type="gene ID" value="CP500_021495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7618" checksum="8130A13C02060A8D" modified="2018-01-31" version="1">MDKSLFELQHAQTLLIQDVAVHFHSRKKGLNLRSNYQFNSKFEKWQSQVPKQEVAVETITKLSCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVU8</accession>
    <name>A0A2G4EVU8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxysome shell protein CcmK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Carbon dioxide-concentrating mechanism protein CcmK</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ccmK</name>
        <name evidence="7" type="ORF">CP500_020275</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the shell proteins of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered. Assembles into hexamers which make sheets that form the facets of the polyhedral carboxysome. The hexamer central pore probably regulates metabolite flux.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer. Interacts with CcmN and CcmO in the carboxysome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Carboxysome</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">The tight homohexamer forms a small pore which is positively charged.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the bacterial microcompartments protein family. CcmK subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial microcompartments protein family. CsoS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000165">
        <property type="protein sequence ID" value="PHX53665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53665">
        <property type="protein sequence ID" value="PHX53665"/>
        <property type="gene ID" value="CP500_020275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00854">
        <property type="entry name" value="CcmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020808">
        <property type="entry name" value="Bact_microcomp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046380">
        <property type="entry name" value="CcmK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044872">
        <property type="entry name" value="CcmK/CsoS1_BMC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00936">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143414">
        <property type="entry name" value="SSF143414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01139">
        <property type="entry name" value="BMC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51930">
        <property type="entry name" value="BMC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="1 5" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="5" id="KW-1282">Carboxysome</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC" evidence="6">
        <location>
            <begin position="4"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="10968" checksum="2E5F8D3A30DC0A67" modified="2018-01-31" version="1">MSIAVGMIETKGFPAVVEAADAMVKAARVTLVGYEKIGSARVTVIVRGNVSEVQASVAAGVESVKRVNGGEVVSTHIIARPHENLEYVLPIRYTEAVEQFRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVX1</accession>
    <name>A0A2G4EVX1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000164">
        <property type="protein sequence ID" value="PHX53674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53674">
        <property type="protein sequence ID" value="PHX53674"/>
        <property type="gene ID" value="CP500_020250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="402" mass="40277" checksum="1AE6BFC7E753AF91" modified="2018-01-31" version="1">MALGQHKRAVGSFSNYRDTELALIELQSSGFPMNKVSVVGENLDQGKVAGAKASTSTDEKVGGGVKAGATAGVVTGGLIGLLGSIGALAIPGVGPVMAGGALATLLADTVVGGAIGATAGGLVGGLVGLGVPEDKAKVYSDRISRGEYLVFVEGTDSEIATAERIFSVRGIQDWGIYDVPTDSGRKVSGRHKRAVGVFSTRSETEQALTELRTAGFDMNRVSVIAKDADSKGEIAGIDVQDSADNKADEGATKGALTGGALGGLTGLLVGLGLLAIPGIGPIMLAGAEATAIATTLAGTALGATAGSLIGALAGLGIPEEEAKVYSDRVSRGDYLVLLNGTEAEVANAEATLNKGGIQNWGVYDYPSVDTARADYGAPGAPGVDTTADIYDPNLGVSSSRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW73</accession>
    <name>A0A2G4EW73_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsF</name>
        <name evidence="5" type="synonym">rps6</name>
        <name evidence="6" type="ORF">CP500_019675</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53771">
        <property type="protein sequence ID" value="PHX53771"/>
        <property type="gene ID" value="CP500_019675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="12785" checksum="BE0CD760731833D2" modified="2018-01-31" version="1">MKPFIYETMYILRPDLGEEMTDQAIAKYQTILRDQGAETIETQHRGKRRLAYEIGKHRDGVYVQMNYTAPGAAIFTMERAMRLSEEVIRYLTIKQDVPDAPEAEAEEVAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW90</accession>
    <name>A0A2G4EW90_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fructose-1,6-bisphosphate aldolase</fullName>
            <shortName evidence="8">FBP aldolase</shortName>
            <ecNumber evidence="8">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fba</name>
        <name evidence="9" type="ORF">CP500_019890</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53726">
        <property type="protein sequence ID" value="PHX53726"/>
        <property type="gene ID" value="CP500_019890"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006412">
        <property type="entry name" value="Fruct_bisP_Calv"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01521">
        <property type="entry name" value="FruBisAldo_II_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="6">
        <location>
            <begin position="233"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="6">
        <location>
            <begin position="275"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="359" mass="38967" checksum="03456CC84F603600" modified="2018-01-31" version="1">MALVPMRLLLDHAAENGYGLPAYNVNNMEQIQAIMRAADETDSPVILQASRGARTYAGENFLRHLILAAVETYPHIPISMHQDHGNAPGTCYSAMRQGFTSVMMDGSLEGDAKTPATYEYNVQVTRDVVNVAHSIGVSVEGELGCLGSLETGMGEAEDGHGFEGALSHDQLLTDPEQAVDFVEQTGVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPQELLEIINSNGGKIRETYGVPVEEIQKGIKCGVRKINIDTDNRLAITAAVRQALFAKPDEFDPRHFLKPSIKFMQKVCSDRYQSFGAAGHGTKIKQMSLDDFAAKYAKGELSSTAKKAVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW91</accession>
    <name>A0A2G4EW91_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF4149 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019490</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53803">
        <property type="protein sequence ID" value="PHX53803"/>
        <property type="gene ID" value="CP500_019490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025423">
        <property type="entry name" value="DUF4149"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13664">
        <property type="entry name" value="DUF4149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4149" evidence="5">
        <location>
            <begin position="23"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="167" mass="18070" checksum="08FBD765253471E9" modified="2018-01-31" version="1">MTAITTSRVESIRPRWQAIVMVALIFWLSGSLIVDLVIMPSLYVSGMMISPDFAVAGNLMFWGFNRVELICAGLAATGLMVLSNLSSGFGKQSRRAIILSLVLLAIALIDTYALTPQMSALGMQLNLFDAAEVPTGMNLLHQGYFGLEAVKLAVGGTLLTWCYQHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWB7</accession>
    <name>A0A2G4EWB7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000150">
        <property type="protein sequence ID" value="PHX53835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53835">
        <property type="protein sequence ID" value="PHX53835"/>
        <property type="gene ID" value="CP500_019355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="14672" checksum="E96BE66C19849557" modified="2018-01-31" version="1">MYQATLTDVSLDPILEQLTQLAQLEPDWDSYGALAVSPVAFVKACQLLIHVKYSLSPLVGDRILPYDAAPIANGSLQLEWRSPQGNLEVEIKPDMSFSYLLIKGEGNERKFEEKNQVSLSEVLNVVSQLLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWC3</accession>
    <name>A0A2G4EWC3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000152">
        <property type="protein sequence ID" value="PHX53821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53821">
        <property type="protein sequence ID" value="PHX53821"/>
        <property type="gene ID" value="CP500_019445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026669">
        <property type="entry name" value="Arsenite_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675">
        <property type="entry name" value="PTHR43675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="64"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="322" mass="35091" checksum="884B1009A253F9E1" modified="2018-01-31" version="1">MTYLETAAKFYSDVAETPQIGLCCVQSSPLQLPGLNIPEQMQEMNYGCGTTVHAAELVGNPVVLYVGVGGGLEALQFAYFSRQKGAVIAVDPVPAMREAAARNLRIAAQENDWFDADFVEIRSGDAFALPMPDASVDVVAQNCLFNIFEPADLTKALTETYRVLKPGGRLLMSDPIATRTIPQHLKQDERLRALCLSGALTYAEYVQHLVDVGFGQVEVRARRPYRLLDKHHYQLEADLLLESLDSVSFKVDVPDDGACVFTGKTAIYRGMKELFDDGAGHVLQRGVPAAVCDKTAGKLGGLMPDKVLITDSTWHYNSGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWF2</accession>
    <name>A0A2G4EWF2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TIGR03943 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000149">
        <property type="protein sequence ID" value="PHX53851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53851">
        <property type="protein sequence ID" value="PHX53851"/>
        <property type="gene ID" value="CP500_019315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015402">
        <property type="entry name" value="DUF1980"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40047">
        <property type="entry name" value="PTHR40047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03943">
        <property type="entry name" value="TIGR03943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="262" mass="29368" checksum="200BC52730EC3178" modified="2018-01-31" version="1">MTVKKLSPWLDALAILGWGILLLKYWISDKLSILIHPNYFGLTVAGGIGLVFIGGFKTWELIKLDRAKQKSRTSPAIDSPRIAEVEHITLFPPSFGSSLMLSVALIGLLTTPRTFTSQTALERGLTESLPITRLQPQEFRNMTKPEMRSLVEWVRLLNFNPEPDTYIGQKVKVQGFVIHPPNIAEQYLWIGRFIITCCAADAYPVGLPVKLPIGQSRVTFPPDSWLEIEGEAIAQELQGKRKLTIQAVSLKSIPEPKNPYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWG0</accession>
    <name>A0A2G4EWG0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycerol-3-phosphate dehydrogenase [NAD(P)+]</fullName>
            <ecNumber evidence="7">1.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(P)H-dependent glycerol-3-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gpsA</name>
        <name evidence="14" type="ORF">CP500_019270</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 11">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000148">
        <property type="protein sequence ID" value="PHX53859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53859">
        <property type="protein sequence ID" value="PHX53859"/>
        <property type="gene ID" value="CP500_019270"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
        <property type="entry name" value="NAD_Glyc3P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="3 7 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7 11" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_Gly3P_dh_N" evidence="12">
        <location>
            <begin position="5"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_Gly3P_dh_N" evidence="12">
        <location>
            <begin position="37"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_Gly3P_dh_C" evidence="13">
        <location>
            <begin position="152"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="227"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX53859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="304" mass="32328" checksum="E8BC9706E1BF4835" modified="2018-01-31" version="1">MAILTIIGGGAWGSALANLATKKGNQVHLWSRRSSFELESVITSTDIVVSAVSMKGVAATVDRLLATNLSPNTIIVTVTKGLDPATTNTPSQIWQTAFPHNPIVVLSGPNLSEEIRQGLPAATVAASFDLSAAKQVQNIYSSEIFRVYVNQDPLGTELGGTLKNVFAIAAGVCDGLQLGTNAKSALLTRALPEMIRVGVRLGAQAETFYGLSGLGDLLATCNSSLSRNYRVGFRLSQGKSLEEILQELQSTAEGVNTTNVLIDLANQRGIEVPVSRQVYRLLNGEITPEQAVLALMERALKPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWG1</accession>
    <name>A0A2G4EWG1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000145">
        <property type="protein sequence ID" value="PHX53874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53874">
        <property type="protein sequence ID" value="PHX53874"/>
        <property type="gene ID" value="CP500_019100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="146" mass="15928" checksum="3897DE2E0DD7A909" modified="2018-01-31" version="1">MGLSDILLDEKNRDTFVDDCVKLIDEQVGSASGFGGLALKAAYSTVKGIRADYCAQVVDQLLPEIAIALDPMWNEAVNNGNPVEYLTERKAQVADELLQISDKKVEHSTRSMVKGAYGKLRPSAKNYVENGIPDLAKIIDKYHSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWT6</accession>
    <name>A0A2G4EWT6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pgi</name>
        <name evidence="9" type="ORF">CP500_018975</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53900">
        <property type="protein sequence ID" value="PHX53900"/>
        <property type="gene ID" value="CP500_018975"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="530" mass="57951" checksum="44C45AC280B88AEE" modified="2018-01-31" version="1">MDATALWQRYQDWLYYHSGLGLYLDISRMGFNDAFVATMKPKFDKAFKDMAALEAGAIANPDEHRMVGHYWLRNSDIAPTSELKQEIVEGIAQVELFVNKVQNRDIKPPFAPQFTDIISIGIGGSALGPQFVSEALSPDIGPLAIHFIDNTDPAGIDRTLNKIKDKLVSTLVITISKSGGTPEPRNGMIEVQKAFAAQKLDFAKQAIAITGVDSQLDKLAKSEGWIATFPMADWVGGRTSELSTVGLLPAALQGIDIRAMLDGAKVMDEATRTTEIKHNPAALLAMSWYFACNGRGEKDMVVLPYKDSLLLFSRYLQQLVMESIGKEKDLDGNIVYQGISVYGNKGTTDQHAYVQQLREGVSNFFLTFIEVLEDRQGVSPEVETGVTSGDYLSGLLQGTRQALYEKQRDSITLTIPQVNPRTVGALIALYERAVGFYGSLVNVNAYHQPGVEAGKKAAAAVLDLQKQVLQVIKDATTPLSVAEIAEKAGMPDQIEIIYKILRHLAANGRNVLLEGNFGQPSTLTTSYKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWW0</accession>
    <name>A0A2G4EWW0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArsR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54035">
        <property type="protein sequence ID" value="PHX54035"/>
        <property type="gene ID" value="CP500_018330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="117" mass="13322" checksum="438FAFCD256CC6EA" modified="2018-01-31" version="1">MKSSQPVPQEVVQQVAEYFSILSEPMRLRILNLLRDGEKCVQELVEATQTSQANVSKHLKLMLQAGILTRRSEGTSAYYKVEDGLIFELSTMVCDRLATRIEQQAQQFRAFTLTTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWW4</accession>
    <name>A0A2G4EWW4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53930">
        <property type="protein sequence ID" value="PHX53930"/>
        <property type="gene ID" value="CP500_018860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="100" mass="11085" checksum="C93237CD173C5F20" modified="2018-01-31" version="1">MSRSISHQAELIESLKDPLEAAPYIEACLEEENSEVLKLALNDVVEARHRMNELSEDVTALLAKLNELLSNKKGAEIYCLSALLDALGFQLTVTVKQRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWX8</accession>
    <name>A0A2G4EWX8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15 16" type="primary">ilvD</name>
        <name evidence="16" type="ORF">CP500_018320</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54029">
        <property type="protein sequence ID" value="PHX54029"/>
        <property type="gene ID" value="CP500_018320"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0408">Iron</keyword>
    <keyword evidence="8 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="473"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="15">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="15">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX54029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="561" mass="58451" checksum="7970846A2ABF5C6B" modified="2018-01-31" version="1">MPENLRSQAVTGGVQRAPNRAMLRAVGFGDGDFTKPIVGIANGYSTITPCNMGLNELALRAIAATKEAGAMPQMFGTITISDGISMGTEGMKYSLVSRDVIADSIETVCNGQSLDGVLAVGGCDKNMPGAMIAIARMNIPAIFVYGGTIKPGHYNGRDLTVVSAFEAVGQFSAGKIDQEELTAVENQACPGAGSCGGMFTANTMSSAFEVMGMSLPYSSTMAAEDAEKADSAAESATVLVEAIRQQLLPSQILTRKAFENAIAVIMAIGGSTNAVLHLLAISNTIGVELSLDDFEIIRGKVPVLCDLKPSGKYVATDLHKAGGIPQVMKMLLEKGLLHGDALTITGKTVAEVLENIPAEPRTDQDVIRPWNNPLYAQGHLAILKGNLATEGAVAKITGVKKPVITGPARVFESEENCLDAILAGKIQPGDVIVIRYEGPKGGPGMREMLAPTSAIIGAGLGDSVALITDGRFSGGTYGMVVGHVAPEAQVGGTIALVAEGDSITIDAPNRLLQLNVSDAELEQRRANWRVPLPRYTRGVLAKYAKLVSSSSIGAVTDLGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX26</accession>
    <name>A0A2G4EX26_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54026">
        <property type="protein sequence ID" value="PHX54026"/>
        <property type="gene ID" value="CP500_018305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="224"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="30014" checksum="005433BD4A36306E" modified="2018-01-31" version="1">MQKIDDGSFPALRNSSNQRDWLEVAEYASIAGSAIGTIVAGLSGQIIYAAAPLTAAIALNFVNRQRFEKQVQQKANSAIAGVELAVKSLQQQVQTLPTEYKELHVLVSDLQQKLRNLESHTLADVHAAVQSLQQQVQAFPAQSEQLYSMLGQLQQQLVSLENSALRELDWENVNVRFLLMNEKLTEVKNITAELQERSHEVDLNQIQGTVRQLQVLVDRPTIDVATIQTEMQQLREQVEKLQRQNQQIVKPYLQRLTRAVKQLLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX45</accession>
    <name>A0A2G4EX45_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CdiA_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000125">
        <property type="protein sequence ID" value="PHX54103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54103">
        <property type="protein sequence ID" value="PHX54103"/>
        <property type="gene ID" value="CP500_017945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040559">
        <property type="entry name" value="CdiA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18451">
        <property type="entry name" value="CdiA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CdiA_C" evidence="1">
        <location>
            <begin position="71"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="19860" checksum="4CC7E47A12F3B8F5" modified="2018-01-31" version="1">MNPEYIQQSKGIYENAEPEYRRSYFDEVAGGFVLIHQQHNLNNSESFVAEVLAKMGKRVTLLSEKAAEGVRTPDAEIDGEICEFKELTKESSNLKNRVQEGFGKAKNQSANAVIFHVNIEIYDIREIDEGIRQAIYWDVNNLMQTIILVFNNQSVQKITREEWENGKRFSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX48</accession>
    <name>A0A2G4EX48_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54122">
        <property type="protein sequence ID" value="PHX54122"/>
        <property type="gene ID" value="CP500_017825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="8039" checksum="031C35FA3D56FBDC" modified="2018-01-31" version="1">MTQQPRIPDLETRQQNVARMRESCRLLDAWTLKLDEVLAMLEADNRRQRQERLDGKYRRVPEKVAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXA9</accession>
    <name>A0A2G4EXA9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Appr-1-p processing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000117">
        <property type="protein sequence ID" value="PHX54182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54182">
        <property type="protein sequence ID" value="PHX54182"/>
        <property type="gene ID" value="CP500_017510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="351" mass="39940" checksum="36BF0E356EC0143B" modified="2018-01-31" version="1">MIKIQQGNLLKANAEAIVNTVNCVGVMGKGIALQFKQAYPDNFRQYEKACRANEVRPGQMFVISTSNLFNPRYIINFPTKRHWKGKSKIEDIQAGLTALIHEVKQLGITSIAVPPLGCGNGGLSWKTVKPLIESAFLELPNVQVLLFEPQGTPEADTMQVATEKPQMTRARALFVSLLQLYGIPGYRLTMLEIQKLAYFLQVAGEPLRLQYVKERYGPYANNLNHVLQKLEGHYIRGYGDRNTEAEIYVLSDGEIAARNFLENTPDAIERLERVSNLINGFETPYGMELLATVHWVVMENRQAAENSENAIALVHEWNTRKRDLFKPQHIRKAWQRLHQQNWFFSAITTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXB2</accession>
    <name>A0A2G4EXB2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54118">
        <property type="protein sequence ID" value="PHX54118"/>
        <property type="gene ID" value="CP500_017800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="350" mass="40067" checksum="4F66F41DD840E61A" modified="2018-01-31" version="1">MNGREVATTFEIPEKLPFLQAICWQVANVKHLSFKEMLCRYESGWDYWGVLGKPSAEELAFIQQISQHYQSWLVAELGSICQPQKTEKWVSLPGMFKREIHQKILTILSHLNVEFLEECHAYFGGGTLVSMQHGEYRLSQDIDFMCPMDGGYNLLRRKVAEGGYDVIFASRDSLLDSFGSRIILPNDIQSNQYGIRFPVIVGGTTIKFEMVCEGRIQFGEPNYPNWSPVPCLNQIDIIAEKLLANADRWPSDRVNSRDLIDLAIQRLATPIPQKAIDKAEAAYQVMEPLMRAIQYFQDRPDYREKCYDILSIAEPNQVINGIDLLAQDLGREITVRTFREIVSLFPSSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXC2</accession>
    <name>A0A2G4EXC2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Exosortase O</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">xrtO</name>
        <name evidence="10" type="ORF">CP500_017810</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54128">
        <property type="protein sequence ID" value="PHX54128"/>
        <property type="gene ID" value="CP500_017810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026392">
        <property type="entry name" value="Exo/Archaeosortase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030996">
        <property type="entry name" value="Exosort_XrtO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019127">
        <property type="entry name" value="Exosortase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09721">
        <property type="entry name" value="Exosortase_EpsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04178">
        <property type="entry name" value="exo_archaeo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04489">
        <property type="entry name" value="exosort_XrtO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="507" mass="55564" checksum="40178AC66BF94EAD" modified="2018-01-31" version="1">MQRTNIPDSGIPDSVSPHPAVNLVLLAPSVLALTWFLANLEAVKWLLSSFVEIPTLYKILISLLIVALVGRSIGSSGRSRRSMPKFIVRRYPVLLMLSAGICSIALQCIIDIKQLTVLLFILGTYGLYGLFCEPYFWQKNLPVAGLLACILPFNTQLNSGLGLPARVLTAQVVEQLLSALQIGAISSYDIIVLENGIAHVDVPCSGIKTLFVGTLFLLSATWIESRKLGLKWLALCATNLLMLVSANAARVAVLVLVAQVFKQQMYAEILHVPLGIVGLISACFFTWLMLQKIPKFSELQPSNLAAKDNSEIFINQPLAKLGVIGIVGVLAIIAQLYHVESAKVAIAPLNIPPQIVSESIALNPSEQTFFGNYPETKTGKIRFVSGNLRGSMLTVASTSWQTYHAPELCFIVSGIPVDRLERKQLTSTILARWLSLKNNQLSATYWLQSTQGTTDNFLSRISSDIRHKNQTWVLVSILFDNLVNPESSEIQDFVTSIHNAVNLSLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXD6</accession>
    <name>A0A2G4EXD6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Solanesyl diphosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sds</name>
        <name evidence="3" type="ORF">CP500_017370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000115">
        <property type="protein sequence ID" value="PHX54204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54204">
        <property type="protein sequence ID" value="PHX54204"/>
        <property type="gene ID" value="CP500_017370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="323" mass="35558" checksum="FCB1251294FF1630" modified="2018-01-31" version="1">MISSTLLFSSVEEDLRLLTENLKQLVGARHPILYAAAEYLFGTKGKRVRPAIVLLMAKATMPDREITEKHRRLAEITEMIHTASLVHDDVVDESDLRRGVPTVHSRFNNRVAVLAGDFLFAQSSWHLANLDNLPVVKLLSEVIMDLAEGEIQQGLNGFDTSLSIEAYLEKSYYKTASLIANSSKAAGCLSEVSAEIADDLYNYGRNIGLAFQIVDDILDFTASTETLGKPAGSDLISGNLTAPALFALEEKPYLEVLIEREFAQEGDIEQALALVADSQGIVRSRELATNHAQKAVHYLAALPHSESRQALIDLAEYVLSRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXH4</accession>
    <name>A0A2G4EXH4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">KGK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000121">
        <property type="protein sequence ID" value="PHX54140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54140">
        <property type="protein sequence ID" value="PHX54140"/>
        <property type="gene ID" value="CP500_017730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014971">
        <property type="entry name" value="KGK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08872">
        <property type="entry name" value="KGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="13478" checksum="EDC37A8469E13AAB" modified="2018-01-31" version="1">MSENFDSLKRDDVVSLYSAEILVTNRTFTISEFLAAMMTLMKAQAGWTELKEMWFREGIDCKILKPGAKSWQRGKVRITLEFEPEQLEVAEITESGKSADTKVVSPLDDLRQKMPKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXH5</accession>
    <name>A0A2G4EXH5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54221">
        <property type="protein sequence ID" value="PHX54221"/>
        <property type="gene ID" value="CP500_017295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10673" checksum="C7C6324696AF0298" modified="2018-01-31" version="1">MKSSVTKTFRKRLNDLPVPVQEQAAKAYEIWQDDPYHPSLQFKQVSQKQPIYSARVSLNYRVLGLLESEHIYWYWIGAHDEYDELLKRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXJ8</accession>
    <name>A0A2G4EXJ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Photosystem II cytochrome PsbV2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_016965</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c family. PsbV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54264">
        <property type="protein sequence ID" value="PHX54264"/>
        <property type="gene ID" value="CP500_016965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029490">
        <property type="entry name" value="Cytochrom_C550"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016003">
        <property type="entry name" value="PSII_cyt_c550"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017490">
        <property type="entry name" value="PSII_cyt_PsbV2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14495">
        <property type="entry name" value="Cytochrom_C550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005890">
        <property type="entry name" value="Phot_II_cyt_c550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03046">
        <property type="entry name" value="PS_II_psbV2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="10">
        <location>
            <begin position="61"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="165" mass="18234" checksum="30D2E1D9C67C848F" modified="2018-01-31" version="1">MLRRGIFVCFLLGILIILPLVLLAPQPVLAATNYVTRYLQVTEPVPMELDAEGHTRLFSAQDLTAGKRLFQQNCLNCHVGGATLPDPTISLSLASLQGATPPRNNINSLVAYLRQPMTYDGSEESFWCRQVPESWMSQPEIEDLAAFVLRAAQKAPGWGTDDFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY23</accession>
    <name>A0A2G4EY23_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Filamentous hemagglutinin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000101">
        <property type="protein sequence ID" value="PHX54433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54433">
        <property type="protein sequence ID" value="PHX54433"/>
        <property type="gene ID" value="CP500_016105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008638">
        <property type="entry name" value="Filamn_hemagglutn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05860">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00912">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01901">
        <property type="entry name" value="adhes_NPXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Haemagg_act" evidence="2">
        <location>
            <begin position="58"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1214"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1282"/>
            <end position="1325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1430" mass="143280" checksum="0F2F794AE978A27A" modified="2018-01-31" version="1">MNAQRALRSILAVIPVAGFWILDFPPNLVFVKENGIGWAIVAIYPQSQIVKAQSIVPAPDNTGTAVTPGPTGRYDITGGSRSKDGANLFHSFTQFGLNSGEIANFRSNPGIKNILGRVVGGDASLINGLIQVSGGNSNLFLMNPAGVIFGTNARLDLSGSFFATTASGIGFDNGWFNGAGANDYAALVGTPNAFVFPAQSGSIVNAGKLAVGNGQNLTLLGGTAISTGELSAPGGQITVAAVPGENVVRLSQPGMLLSLEVSPGQGVSGGAVLPFSPLSLPRLLSGRGVENATGISTNAQGQVVLTGVDTVLAGAGTAVVSGAVDVSAARGSGGTVNVLADRVGLFGANINASGADGGGTVRIGGDYRGAGSVPNARMTYVDGKSAIAADATQFGNGGKAIVWADNTTAFLGRISARGVSATPGTSGVGGFVEVSGKQRLVFNGTVDTTGTNGLGTLLLDPENIVITDAGSTGEWPFAPTDAAVIANGNILATAISTTNSPQQNGSATSLTISARALESISGRTNVVLEALNDITIADLAGDRLSFQATTGSVTFRADADRNGTGSFSMNAADRISTAGGAIAIYGSQITAGNLSSNGGNISLTSSGSTVANNISTSNLNTGSSGNILIEGLNITAEKLDTTGYKNAGNVSLTAQNTLTIRGITADSGNITLTGNEIDLKGGSNSVNGTGFLTLQPWNPGQNIAIAGTGDIGTNTFLNLTANDLESLRNGFAGITIGRNNSSGAVLVANNFTFYDPLIIQSPSPAGTITTTSSLIGADNASLTLKADGNIRTGNISTNGGEIRITSQTGNIITDRLRTGTTASTGEWPFAPTNTTVGAKVDSPLPQAKVDSPLPQVSRSAGDVTLNAEGKVTVGAIDSRGDIAGNVILTGPKGVSVGAIEAGGLQTPGNITLSGSEIDLTGDKNSVASNGSLVLQPTDPRHNITIGGSGDTEALDLTAAELGTLRNGFVSIAIGRFDGSGLMTISPRIPTSTPTSTVGANGHSPLPLTFQDPIVIRSPLGTGAIVGTGAIAGIDNASITLTAGTVNVGDVTSNSGINITSSQGNVKTGVVSSRSTNGVAGDINIRSAGSIESGNVDAFGSKTGGDISITAPGRIATGVINSSSESGKAGSSTITGQKDVEVAAIKARGNTGGDVDVTAGGLFRAPGTGTNTDIASVSISTDGQVRSGSQTLLQSTCKSGTCTLTPLDVPAKSNASAATTAKSPRLIAPSPAPTSTVGANGYSPLLKTTGNSQELVAVPSSIANQPTANSSPTILSSEPAAGTLSTAQTATQPAAQPLSSSVIKNNLGTSDGSTNGDGTQKPGTSGNMSLIVPESSRIGGAIGQINPIDAVQQRDKIQGREFERYFGGKGEWPFAPTEKSVTPQSIRDTLSSVNRLTGVKPAIVYVWAKADHLEETVGECLRGFTHQTSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY25</accession>
    <name>A0A2G4EY25_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_018035</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54067">
        <property type="protein sequence ID" value="PHX54067"/>
        <property type="gene ID" value="CP500_018035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029095">
        <property type="entry name" value="NarX-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13675">
        <property type="entry name" value="PilJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="240"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="494" mass="55844" checksum="DA307F8F10714B3E" modified="2018-01-31" version="1">MMTISSANKTYRHSSVESEVLPVMVLKNYFNIEEIMTARKISAAIINLSGRQRMLSQKTAFFAMRLVGSPETAEREQLRADLLDAIALMEKSHSALINTDSSINLLNPPSPAVKAMYFEAPLYLDKQLCEYIDRIKALVQVPDAELKPDNAHLLYIIAAASGELLQAFDAVVSQYQYESEVEQFEIDIRQVELYQESCAATAASIAKASELDRTLCELKETQAQLLHSEKMSSLGELMASIVHEINNPVSFIYGNLSHVEVYTQDLLHLLRLYQENYPNPSEEIQDQIEEMELDFLLEDLPKVMSSMQMGSDRIREIVKSMQNFSRSDHSSMTLCDLHDSIDSTVLILRNRLNPQKNRRDIDIVKDYGKLPSVECYAGQLNQVFMNLISNAIDALEEAAEEKPDTLLKIYIRTELAENDRVRVRIADTGSGITAQVKERMFEQFFTTKKIGKGTGLGLSIVYKILVENHRGILRCESEPGKGTEFIIELPVQQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYB0</accession>
    <name>A0A2G4EYB0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Photosystem II CP47 reaction center protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">PSII 47 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Protein CP-47</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">psbB</name>
        <name evidence="11" type="ORF">CP500_015945</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.</text>
    </comment>
    <comment type="cofactor">
        <text evidence="9">Binds multiple chlorophylls. PSII binds additional chlorophylls, carotenoids and specific lipids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cellular thylakoid membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PsbB/PsbC family. PsbB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54476">
        <property type="protein sequence ID" value="PHX54476"/>
        <property type="gene ID" value="CP500_015945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045156">
        <property type="term" value="F:electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009772">
        <property type="term" value="P:photosynthetic electron transport in photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01495">
        <property type="entry name" value="PSII_PsbB_CP47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000932">
        <property type="entry name" value="PS_antenna-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036001">
        <property type="entry name" value="PS_II_antenna-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017486">
        <property type="entry name" value="PSII_PsbB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33180">
        <property type="entry name" value="PTHR33180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00421">
        <property type="entry name" value="PSII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161077">
        <property type="entry name" value="SSF161077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03039">
        <property type="entry name" value="PS_II_CP47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="7 9" id="KW-0157">Chromophore</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="509" mass="56416" checksum="582678D4865F937C" modified="2018-01-31" version="1">MGLPWYRVHTVVLNDPGRLISVHLMHTALVAGWAGSMALYELAIFDHTDPVLNPMWRQGMFVLPFMTRLGVTGSWGGWSITGEGNVDPGYWSFEGVAAAHIVLSGLLFLAAVWHWVFWDLELFRDPRTGEPALDLPKMFGIHLFLSGLLCFGFGAFHLSGLFGPGMWVSDPYGLTGHVQPVAPAWGPEGFDPFNPGGIVAHHIAAGVVGVIAGLFHLSVRPPERLYKALRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSAATPIELFGPTRYQWDGGYFQQEIDRRAQASLAGGASFQQAYEQIPEKLAFYDYVGNSPAKGGLFRAGAMVNGDGIAKTWLGHPVFTDSEGRVLSVRRLPNFFETFPVILTDKDGIVRADIPFRRAESKYSFEQTGVNVTFYGGQYNGQTFNSPLDVKRFARAAQKGEVFEFDRETLKSDGVFRTSTRGWFTFGHACFALLFFFGHIWHGSRTIFRDVFAGVEADMEEQVEWGLFQKLGDKSTRREESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYE5</accession>
    <name>A0A2G4EYE5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">30S ribosomal protein S1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54480">
        <property type="protein sequence ID" value="PHX54480"/>
        <property type="gene ID" value="CP500_015965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="32"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="119"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="197"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="398" mass="44034" checksum="D094D0F0E45956B2" modified="2018-01-31" version="1">MVNTKTTVKEIGFTHEDFAALLDKYDYHFSPGDVVAGTVFSIEPRGALIDIGAKTAAYIPIQEMSINRVENPEEVLQSNETREFFILTDENEDGQLTLSIRRIEYMRAWERVRQLQAEDATVRSQVFATNRGGALVRIEGLRGFIPGSHISTRKPKEELVAEELPLKFLEVDEDRNRLVLSHRRALVERKMNRLEVGEVVIGTVRGIKPYGAFIDIGGVSGLLHISEISHDHIDTPHSVFNVNDEVKVMIIDLDAERGRISLSTKQLEPEPGAMVKNRELVYEKAEEMAAKFREKMLAQKQAKAGIAIPVDAIDSDELSDEILEDVPSAMEEDLPEETTAVVTEATPEATPEAATEAVTEATPEATPEPVTEATPEPVTEATPEATLEVSAEIPPTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYG0</accession>
    <name>A0A2G4EYG0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Phycocyanobilin:ferredoxin oxidoreductase</fullName>
            <ecNumber evidence="3 6">1.3.7.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pcyA</name>
        <name evidence="7" type="ORF">CP500_015745</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(2R,3Z)-phycocyanobilin + 4 oxidized [2Fe-2S]-[ferredoxin] = biliverdin IXalpha + 4 H(+) + 4 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:15309"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57437"/>
            <dbReference type="ChEBI" id="CHEBI:57991"/>
            <dbReference type="EC" id="1.3.7.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the HY2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.7.5" evidence="3 6"/>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54518">
        <property type="protein sequence ID" value="PHX54518"/>
        <property type="gene ID" value="CP500_015745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050620">
        <property type="term" value="F:phycocyanobilin:ferredoxin oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010024">
        <property type="term" value="P:phytochromobilin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00618">
        <property type="entry name" value="Ferredoxin_bilin_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009249">
        <property type="entry name" value="Ferredoxin-dep_bilin_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022870">
        <property type="entry name" value="Ferredoxin_bilin_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34557">
        <property type="entry name" value="PTHR34557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05996">
        <property type="entry name" value="Fe_bilin_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="245" mass="28489" checksum="60F9ECADA258BF93" modified="2018-01-31" version="1">MLDISKPSLREQQHYLIRELADRIEAVWRRYLDLEPYHLPADLGYVEGRLEGEKLIIENRCYQTPQFRKIHLELAKVGPMLDILHCVMFPRPNYALPMFGTDIVAGKGQISAAIADLSPLNSDRTLSETYRTRLQTLPVNQFSCPRQIPDWGDIFSEFCLFVRPDSKEEENRFLDIVESYVEIHCKLAIASEPVSVAEASKILDAQIYYCTQQQQNDKTRRVLEKAFGQDWAEHYMTEVLFDFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYG9</accession>
    <name>A0A2G4EYG9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54574">
        <property type="protein sequence ID" value="PHX54574"/>
        <property type="gene ID" value="CP500_015430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8829" checksum="B378D3D40EC22A60" modified="2018-01-31" version="1">MKLISLSAHFDGQSIQLDEPYKLEPNIKLIVTVLPEQLAEREAWLWLSRHQLNNAYSQDDDYPTNAIKTLNPDYAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYM5</accession>
    <name>A0A2G4EYM5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar assembly protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54596">
        <property type="protein sequence ID" value="PHX54596"/>
        <property type="gene ID" value="CP500_015265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="41857" checksum="640E017FA730EFAF" modified="2018-01-31" version="1">MTRFIHDRFAKEYLEELLSPIGTVNIGRDVAAEVREIDVYFIPGTAIPEYSATLGLLGKMASTTAIFEPFRNPVSVGEVISCMGKLWDLRGELERQARRENTQYDDTKLPRLWILTPTASKPLLEGFGAIPNPENWVKGVYFLPTHLKSAIVVIHQLPETPETMWLRILGKGGVQQRAIAELSSLATDDPLRIIALELLYRLQSHLVAETQEESEPEERELIMAIAPLFREQIQAAQQQAREQGLEQGLEQGLEQGLEQGRQAQQRLILENFLQVRFGEINSKMTALLSPISNFSAADFTVLLLAISMLTVDEAGRQQAVRLLAENVLKMRQSELGDLLPTALTNLLALPVDELTLFVEQLPQLSADELRARLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYN0</accession>
    <name>A0A2G4EYN0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54634">
        <property type="protein sequence ID" value="PHX54634"/>
        <property type="gene ID" value="CP500_015025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11600" checksum="7BA0459C1EFDFABB" modified="2018-01-31" version="1">MLFGCINVARLRSSREQESARWALASLVATRAARSSSIEQTRHQKVANFVVEISVWRSPPMPKPYSYDLRKKVGANGKRAPTHIEQDGMKKSEVSQLFNKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYU2</accession>
    <name>A0A2G4EYU2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54648">
        <property type="protein sequence ID" value="PHX54648"/>
        <property type="gene ID" value="CP500_014915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="11964" checksum="52852500369EDE91" modified="2018-01-31" version="1">MDEFVRKAAALGLPAIMLLIVMATTGLAGAAAITTALATLGGPAGMLGGIALLGIIGLATEMLSKYGLEALLIAIYRQRIQNGESRLNIRKEIRKLPISRELRRRLDEEFGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYY6</accession>
    <name>A0A2G4EYY6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54731">
        <property type="protein sequence ID" value="PHX54731"/>
        <property type="gene ID" value="CP500_014575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7071" checksum="6E3B908DD849379A" modified="2018-01-31" version="1">MAIAIPDLSDRQKAEILAEFMSAAIHLNVHCGEDFQTLIAEEMENLSDDDEEDFEQINRVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ40</accession>
    <name>A0A2G4EZ40_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF488 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54457">
        <property type="protein sequence ID" value="PHX54457"/>
        <property type="gene ID" value="CP500_015995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007438">
        <property type="entry name" value="DUF488"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04343">
        <property type="entry name" value="DUF488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="207" mass="23409" checksum="F5AE9E45C000B14B" modified="2018-01-31" version="1">MELFTIGHSNLSIEAFVLLLQKHQITAVADVRSHPFSRYLPHFNQSEIKASLSSVGIQYVFLGKELGARPEDLSCYDLSGKALYQRIAATPLFSEGIQRLLKGAASYKISLMCAEKDPITCHRTILVCHKLKDFNVEINHILSDGNLESHHDLETRLIHKFNKGKKSDEPIQLSLFELEPVKTEIIDLESAYYRHGLEIAYVTKEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ97</accession>
    <name>A0A2G4EZ97_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_013970</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54831">
        <property type="protein sequence ID" value="PHX54831"/>
        <property type="gene ID" value="CP500_013970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="516" mass="55038" checksum="CD8957171FC5F592" modified="2018-01-31" version="1">MSNKIIQAIKSSGILGAIASLTVLLFGGWSGTVIGWLMGTAAGFMACQEQKVYNPKMGATIGSLAGLGLGVWLLVASIVEGVVIRPFSGQSAVDFPTTLLYGICSLAIATFTATLMGALQGLPNDRQRLATLVTLAFILILFPFIDIQAKTGWIATVVQIQIFIMLALGLNITVGFAGLLDLGYAAFFAIGAYTTALLSSGQLNIAWNFWIVLPIAAGVAGISGVILGIPTLRLKGDYLAIVTLGFGEIIPVVFRNLTAIRIDEPVSKIVASLLGKPELVLCLVGCDRPFNLTGGEAGINPIGRPSLPIIGTFSTGNYFPWYYLILFLVVFAYFMISRLRDSRLGRAWNAMREDELAASAMGINIVKTKLSAFAMGATFSGFAGAFYAAYISAIFPSVFDFSVSVIILCMVILGGLGNMTGVILGAIIIMSADRLYLPQLAQVLKGFLNTFVLPRIAIPQLADFLATSLDPIQMRLFLFGLTLVVMMIVRPEGLIPDKIHQAELHEDAEASNESLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZK9</accession>
    <name>A0A2G4EZK9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transglut_core2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0162 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54944">
        <property type="protein sequence ID" value="PHX54944"/>
        <property type="gene ID" value="CP500_013385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transglut_core2" evidence="2">
        <location>
            <begin position="42"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="273" mass="31387" checksum="893489CBFEB8EA67" modified="2018-01-31" version="1">MDFPRARQLFYREINQPDSSIDLAKAALYIALEEYPDIEPEEYLNILDTMADELRDRLPAQNYPLRIIQTINRYLYEELLFAGNDADYYDPRNSFLNQVIDRRTGIPISLSLVYLEVAKRIDFPMVGIGMPGHFLIKPDFADAAIFVDAFNGGEILFTQDCQDRISQIYGQVMELQPTFIAPVSPRQLLARMLGNLKAIYLQQGDAVRVLRAVERILLLFPDALGERRDRGILYYQLGRLAEARHDLQIYLINAPNAPDAARIRQMLDRLDGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZS9</accession>
    <name>A0A2G4EZS9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55019">
        <property type="protein sequence ID" value="PHX55019"/>
        <property type="gene ID" value="CP500_012960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018775">
        <property type="entry name" value="RlaP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34817">
        <property type="entry name" value="PTHR34817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10127">
        <property type="entry name" value="RlaP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="36176" checksum="29D9A37FBD8C6A58" modified="2018-01-31" version="1">MANANIPQNFNLILPAGTQIVTKIEVKNPATNESWKQGLVGVIVKSPTDNSHAYLVKLPDGTQISLRRHEFSIRKQFQSEGLQSGGDFLAEYNLYDSVIYRCIVGSRAYGLDNKQSDTDRRGIYLPPAMLHWSLYGIPEQLENKQNDECYWELQKFLIVALKANPNVLECLYTPLVETVSPIAQELLDIREIFLSKLVYQTYNGYVLSQFKKMEQDLRNTGEVRSKHAMHLIRLLLSGITVLKEGFVPVRVDDYRSQLLSIRNQEVPWDEVNRWRLDLHGEFDRAFGSTRLPERPDYEKANQFLIKARRSAIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZU5</accession>
    <name>A0A2G4EZU5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55030">
        <property type="protein sequence ID" value="PHX55030"/>
        <property type="gene ID" value="CP500_013015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013558968" evidence="1">
        <location>
            <begin position="28"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="13979" checksum="5BF335693010ADA8" modified="2018-01-31" version="1">MKPNIRLVSLLALSVVAVGVSPTLSNANPSPQGEFDETTIVSNNIELNRAKNLARQAAESANGGLGQYRAEPSMHGVSSEAPFVDNNDGTWTFSFKGSRPGSSVFRIESVVTVSRNGTVRIDYNGPIRNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZW5</accession>
    <name>A0A2G4EZW5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inorganic pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55059">
        <property type="protein sequence ID" value="PHX55059"/>
        <property type="gene ID" value="CP500_012915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="182" mass="20596" checksum="DD43C2867E8CE172" modified="2018-01-31" version="1">MNNWNSQSGDIEWVDQVYQLLLEIARSSLSDIPRIPENITQKALPLIQKVQSIQQRRDGQVFSSGSFSVNDREWVDQVCQLLVELTGASLSERPKMPENIAGRALILADKAQNIKEIIEENATLAPADEDDDPLQSPDALLNLLHHSLKTQRAKSYKPDAPQWQQVLSLIDVVQSIYKQIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZY8</accession>
    <name>A0A2G4EZY8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Maltokinase</fullName>
            <ecNumber evidence="5">2.7.1.175</ecNumber>
            <ecNumber evidence="6">5.4.99.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Maltose alpha-D-glucosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Maltose-1-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">treS</name>
        <name evidence="14" type="ORF">CP500_012720</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-maltose = ADP + alpha-maltose 1-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31915"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17306"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.175"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-maltose = alpha,alpha-trehalose</text>
            <dbReference type="Rhea" id="RHEA:15145"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17306"/>
            <dbReference type="EC" id="5.4.99.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the aminoglycoside phosphotransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family. TreS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.175" evidence="5"/>
    <dbReference type="EC" id="5.4.99.16" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55080">
        <property type="protein sequence ID" value="PHX55080"/>
        <property type="gene ID" value="CP500_012720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047471">
        <property type="term" value="F:maltose alpha-D-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040999">
        <property type="entry name" value="Mak_N_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032091">
        <property type="entry name" value="Malt_amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012810">
        <property type="entry name" value="TreS/a-amylase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012811">
        <property type="entry name" value="TreS_maltokin_C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18085">
        <property type="entry name" value="Mak_N_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16657">
        <property type="entry name" value="Malt_amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02457">
        <property type="entry name" value="TreS_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02456">
        <property type="entry name" value="treS_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="13">
        <location>
            <begin position="20"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX55080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1126" mass="129615" checksum="D97355EBD81F8558" modified="2018-01-31" version="1">MQNSILNNDPLWFKDAIIYEVPIQAFADSNADGIGDFRGLTEKLDYLQNLGVTAIWVLPFFPSPLRDYGYDTSHYTTVNPIYGTLEDFKHLLEQAHLRGIRVIIELIVNHTSDQHAWFQKARRSPKGSKERDFYVWSDTPEKYQDARIIFQDFETSNWAWDGVAKAYYWHRFYSHQPDLNYDNPAVVQAILDVVDFWLELGADGLRMDAVPYLYEREGTNCENLPETHVFLKHLRKHVDEKFPNRMLLAEANQWPEDAVEYYASGDECHMNFHFPLMPRLFMSVHMEDSFPIIDILQQTPQIPNNCQWALFLRNHDELTLEMVSDEDRDYMYRVYAQDTQARINLGIRRRLAPLMGNNRRRIELMNALLLSLPGTPVLYYGDEIGMGDNIYLGDRNGVRTPMQWSGDRNAGFSRANPQRLYAPPIVDPEYHYESVNVEAQRANPSSLWWWMKRLIAIRQRFQAFGRGTCEFLYPENRKVLAFVRTYQDEHILVVANLSRFVQTAELDLSPFKGAVPVEIFGRTEFPAVGDSAYFLSLSPHSFYWFTLTVKKDNVSLHLPQAELPKFAVSGNWKTAFATSKLTDDLVSILPEYLRSSKWFTGTDRKIQSLQIGEILPVECKNSTGLESTIYILLLQLNYTEGMAETYVLPVGWEEIQGDADERAIARIQFLERNEVGVLFDATTDRDFLIALLEAIANSRSYTGAAGKLLGIPDKALTSEPDLSQLEPHLFRKEHSNTSVSYGDRFVLKLLRKVEEGINPELEIGRFLTDRKLIQHFAPIVGALEYQAEGKPVMAIGILQKLIPDSRDAWSYTLDTLRDYFEQAMTVEAKYSTDNLSTAPENYLPNANPALMQRQSNSLKSDLSLEIPELARELIGSYLASAELLGQRTAELHLALGSDTQNPDFAPENFTSFYQRSIYQQMRNLAGRTLLLLKKRLSQLPPATQKLGQNLLNREDLLMERFKSILNLRITADRIRCHGDFHFGKVLYTGKDFVIINFGGERNRPLSERRMKRSPLRDVAGMLQSFNYAVTLGLRNEVESGMIRPENLSEMQQWGNVWDRWVGLTFVKSYLATAADANFLPKSIPEIQVLLDAYILEKTVSELVYELNYRLDWVEIPLERLLKLLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZZ3</accession>
    <name>A0A2G4EZZ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">General secretion pathway protein GspH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55075">
        <property type="protein sequence ID" value="PHX55075"/>
        <property type="gene ID" value="CP500_012695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031975">
        <property type="entry name" value="Pilin_GH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16734">
        <property type="entry name" value="Pilin_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="184" mass="20356" checksum="ACAD717304CBAB9B" modified="2018-01-31" version="1">MTKNQESIVDNAVYDRNSPIYAGCGCLVLLMLCIGIITVIALLFWSDRSSLAQARHKKQLQARSYLYSMNKIQQAYFAEKSVFSTSIKEVGIKTETENYKYFIFSTKIAVFNYGVSKQKDVKSYVGGVFVIPAAKQVDLNSYNMTMTTTSILCIADSPGTIKPPEPTNQNGKIACGTGTTEVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F077</accession>
    <name>A0A2G4F077_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nitrate ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ntrB</name>
        <name evidence="8" type="ORF">CP500_012360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55169">
        <property type="protein sequence ID" value="PHX55169"/>
        <property type="gene ID" value="CP500_012360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005889">
        <property type="entry name" value="NtrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01183">
        <property type="entry name" value="ntrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="86"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="280" mass="31087" checksum="CED42EE53F5C0661" modified="2018-01-31" version="1">MAVSKSRKSGDIQGAFGEFWKKNSQNILPPILGLLGFLFIWQFLSSTGLIKLPPPTSVWTDERTRILLMYPFMNSKTYGVGLFWQTLASLERVAKGYTLAAAVGISMGVVVGTNPFLNKALDPIFQFLRMVAPLAWVPIALAALQQNEPAALFVIFITSVWPILINTAEGVRQIPDDYNNVAKVLQLSRKEYYINILFPSALPYIFTGLRIAIGLAWLAIIAAEIVMSGITGIGFFIWNAYQQNYISEILLAVFYIGAVGLMLDRMMAWLQNKIAPSQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0D3</accession>
    <name>A0A2G4F0D3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidinol dehydrogenase</fullName>
            <shortName evidence="5">HDH</shortName>
            <ecNumber evidence="5">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 12" type="primary">hisD</name>
        <name evidence="12" type="ORF">CP500_011825</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6 11">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55221">
        <property type="protein sequence ID" value="PHX55221"/>
        <property type="gene ID" value="CP500_011825"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="1 5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5 7">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 7">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="362"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX55221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="437" mass="47303" checksum="E8CDDE7AB010DD9C" modified="2018-01-31" version="1">MLRIITQWVEAQAELRRICDRTHDELVVHKEATVREVLQAVKRKGDKAVLHYTAEFDRMTLNAEELRVSGAELDAAYQQVSKELLNAIRTACKQVEAFHRQRVPKSWVQFGDDEVVLGKRYTAVDRAGIYIPGGQASYPSSVIMNAVPAKVAKVPRLVMCTPPGQEKKMNPAVLVAAQEAGVDEIYRVGGAQAIAALAYGTETIPKVDLITGPGNIYVTLAKKLVYGTVGIDSLAGPSEVLIIADGKANPVHVAADMLAQAEHDSMASAILLTADSVLARKVVAEVERQLANHPRRTLTEKAIVNYGLVVVVDSLKTAAELSNEFAPEHLELQVADPWALLPQIRHAGAIFLGYSTPEAVGDYLAGPNHTLPTSGAPRYASPLCVETFMKHSSLIEYSPTALKKVAKAINVLAEAEGLPSHADSVRLRTENQGDAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0F2</accession>
    <name>A0A2G4F0F2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55218">
        <property type="protein sequence ID" value="PHX55218"/>
        <property type="gene ID" value="CP500_012025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008884">
        <property type="entry name" value="TylF_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40036">
        <property type="entry name" value="PTHR40036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05711">
        <property type="entry name" value="TylF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="28249" checksum="50525EE355C0F45C" modified="2018-01-31" version="1">MDNTFIATYFDWDHRTPRKRHRLANRVLNKFRLNGQVIPKTPGMASVEARMNIFHLASQTAAYKVDGDVVEVGCNAGESSIVIQKVLHEYAPEKQFHVFDSFEGLPELQGQDLKDGIYDKGSMTARLDAFKKNFFDVGLDLPHIHKGWFQDTVPSCLPDRISFAVVDCDLYTSTKYVLPHVYERLMPGAICLFGIYYDEKVFSRPYTAGPFKSPGVKRACDEFFEDKPEKVSVLYACEYSNGYFRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0R0</accession>
    <name>A0A2G4F0R0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Potassium-transporting ATPase potassium-binding subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP phosphohydrolase [potassium-transporting] A chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Potassium-binding and translocating subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Potassium-translocating ATPase A chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">kdpA</name>
        <name evidence="10" type="ORF">CP500_011385</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the KdpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55340">
        <property type="protein sequence ID" value="PHX55340"/>
        <property type="gene ID" value="CP500_011385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00275">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004623">
        <property type="entry name" value="KdpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30607">
        <property type="entry name" value="PTHR30607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03814">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001294">
        <property type="entry name" value="K_ATPaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00680">
        <property type="entry name" value="kdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 9" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="412"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="482"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="528"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="582" mass="62231" checksum="2984D785533B62A9" modified="2018-01-31" version="1">MLEGFIQIALTLIIVVAIAPVFGNYMARVYMGEPTILDPAIKPVEQFIYTASNIRSSDSMTGWQYARSVFYSNVAMGIFVFLILMFQGWLPLNATGLGAPTWDTALHTTISFLTNTDQQHYSGETTFTYLSQLTLGFLMFTSAATGLAVGIAFIRGLTGRPLGNFYIDLIQSITRILLPLSLIIGLLLLICGVPETLAGPAVATTLEGSTQVIARGPVAHFESIKQLGENGGGFFAINSAHPFENPNPFTNLLETIAMVSIPAALIHTYGIFANNKKQGWLIFGMVLGIYIFLISITAVGEFQGNPQINNFLGSVQPNLEGKEIRFGWAETALWAVTTTGTMCGAVNGMHDSLMPPGSFATLFNLFLQIVWGGQGTGTAYLFIYLILSVFLTGLMVGRTPEFLGRKIEKREIVLASVVLLIHPIAVLIPGAIALAFPDSLSGISNPGFHGISQVMYEYASAAANNGSGFEGLADSQPASSGIWWNLSTCFSMLLGRYVPIVALLLLADSMTNKQPVPETTGTLRTDSILFTSVTAGVIIILGALTFFPVLALGPIAEGFEISSAKLETAPITAPSPLATPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Z3</accession>
    <name>A0A2G4F0Z3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BrnT family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55423">
        <property type="protein sequence ID" value="PHX55423"/>
        <property type="gene ID" value="CP500_011075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038573">
        <property type="entry name" value="BrnT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007460">
        <property type="entry name" value="BrnT_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04365">
        <property type="entry name" value="BrnT_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="7023" checksum="5CDD1DEF2058B14D" modified="2018-01-31" version="1">MVFDPFYQEGDASTNDELRDFILGNSLSQRLLLVVYVERGLRSRIISSRPATRTERQLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F189</accession>
    <name>A0A2G4F189_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_010530</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55531">
        <property type="protein sequence ID" value="PHX55531"/>
        <property type="gene ID" value="CP500_010530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PTHR22573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="4"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="158"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="272"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="422"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="475" mass="51322" checksum="DA0E61AEDFCE12FB" modified="2018-01-31" version="1">MNPIKFGTDGWRGIIADDFTFDRVALVAPLAAQVLGQTGGNDATSGTVIVGYDRRFLAEDFALTAAKAVQNAGFDVLLSDSYAPTPAFSLAAKQLNALGAIVLTASHNPGAYLGLKVKGGFGGSVSPEVTQQIEAKLENPAPISATPGKLESFNPWPPYCKTLREMVDIDAIKSAIASHKITVFVDVMHGAAAGGLAQILEETVHEVNSDRDPLFGGGAPEPLPRYLSQLFRVMRTHQRKSSGLSIGFVFDGDSDRIAAVDSSGNFLSSQILVPILIEHLAKRRGLSGEVIKTVSGSDIMPKIAELYGLPLFETPIGYKYIADRMLTTQVLVGGEESGGIGYGTHIPERDALLSALYLLEAVVKSGEDLSDIYRRLQTETGFTSAYDRIDLHLANMDERSRLLDLLQNQPLTEIACKAVVDCNKVDGYKFRLADGSWLLIRFSGTEPVLRLYSEAATLKEVMQNLNWAKSWAQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1F8</accession>
    <name>A0A2G4F1F8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_010005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55601">
        <property type="protein sequence ID" value="PHX55601"/>
        <property type="gene ID" value="CP500_010005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="25"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="320" mass="35508" checksum="F3D332742C796987" modified="2018-01-31" version="1">MIEIDTEQMYTVENIGELNQNNVSQRLDIWLSNQIPDLSRSRVQTLISQGNVKVNDETCTSKKISVKTGDRIHLTLPETQPTSLQPESIPLDILYEDDSLIIINKPAGLVVHPAAGHPDGTLVNALLAHCPLSAIGGVQRPGIVHRLDKDTTGAIAIAKTDIAHQHIQAQLKTKTARREYLGIVYGIPNAETGTVDLPIGRHPTDRRKMGIVPVEKGGRDAITHWQIKERIGNYSLIHYQLETGRTHQIRVHTAEIKHPIIGDPMYSSNRSIGVNLTGQALHAWRLQLEHPISGELIEAIAPLPDQFNTLLRILRLRAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Q7</accession>
    <name>A0A2G4F1Q7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2834 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55686">
        <property type="protein sequence ID" value="PHX55686"/>
        <property type="gene ID" value="CP500_009300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="219" mass="24378" checksum="ADCA7FEFEEA8355E" modified="2018-01-31" version="1">MFRKIGFWLLWIAFSTYAFVFAPPDSPETITLITNLSTGKVADINPLIVALFNIMGIWPLIYSCVLFTDGRGQKIPAWLFATLSFGVGAFALLPYLALREPNPEFLGKKNVFLKILDSRFTGILLTLGAVALVALGLTKGDWSDFVQQWQTSRFIHVMSLDFCMLSLLFPALLADDMARRGMQNTTAFWAVTLVPLFGPLAYLCTRQQLPQNGAETVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1U2</accession>
    <name>A0A2G4F1U2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_009190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55743">
        <property type="protein sequence ID" value="PHX55743"/>
        <property type="gene ID" value="CP500_009190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="SSF161084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="136" mass="14690" checksum="DE835E0C95AD56DC" modified="2018-01-31" version="1">MGLPVSVILLDCIAAAAALVYAPFLVVAFARLQLGYDQAAPRAMFDKLPGYAQRATWAHQNSFETFLLFLAAALMAFVTGVDSEAAGWAAIAFPISRLLFSVFYILNVPLGRSLMFAIGSSCTFSLFYFSLMTVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F226</accession>
    <name>A0A2G4F226_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_008920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55799">
        <property type="protein sequence ID" value="PHX55799"/>
        <property type="gene ID" value="CP500_008920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="384" mass="40614" checksum="ECDDCCF0FE659809" modified="2018-01-31" version="1">MAILDGLFNGISIGAVLLIAALGLAIIFGLMGVINMAHGELMMLGAYTTFVVQNVFKGIGGFAFETYILFAIPSAFLVAALVGLILERGVIRYLYGRPLETLLATWGVSLILQQFVRSVSGVLVTGIAVFCLLFFGGLQVLKRRPDFERVRKGIIAILLPLSLGISWAVSAFLGETYKLAVTKPWFGAQNVDVTAPAWLRGGIPLGSFQLPYARLFIIALTGLCLAGIYLFLQKSVWGLRIRSVTQNRSMSACLGIPTEQVDALTFALGSGLAGVAGCAISLLGSVGSNTGQNYIVDTFMVVVVGGVGKIMGSVVAAIAIGTANYLIGSGTLALILAPVKPLADFFTFFATTSMAKVMVFALIIAFLQVRPGGIFPQKGRTVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F273</accession>
    <name>A0A2G4F273_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55846">
        <property type="protein sequence ID" value="PHX55846"/>
        <property type="gene ID" value="CP500_008730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="210" mass="23450" checksum="3AA927C6C96E24C7" modified="2018-01-31" version="1">MVANIPDYAPQLQCLMEQAGLEGDRALSQKAGISELELSRLRRGLALQTRVDILLKISQALQISLNELLATFAPGSVELEQPAPTAMQQEYQRLQATLDVQRESLMQEFQLSSLQILESWMLQWPTAASKAQENQHLPAVKLLPLMRPVEKLLQEWGVEAIAPVGSSIPYNPQQHQLLEGTAQPGEAVKVRYTGYRQGDKLLYRAKVIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F276</accession>
    <name>A0A2G4F276_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55874">
        <property type="protein sequence ID" value="PHX55874"/>
        <property type="gene ID" value="CP500_008430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7526" checksum="D1D595309DD538E1" modified="2018-01-31" version="1">MVHIRFEGRSYDVAENQLGIATGMSEKAIKERLAKHFDVKGDRFESYVLDRRPSGDLIVRPEAVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F281</accession>
    <name>A0A2G4F281_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromophore lyase CpcS/CpeS</fullName>
            <ecNumber evidence="3">4.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cpcS</name>
        <name evidence="4" type="ORF">CP500_008545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CpcS/CpeS biliprotein lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.-.-.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55870">
        <property type="protein sequence ID" value="PHX55870"/>
        <property type="gene ID" value="CP500_008545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017009">
        <property type="term" value="P:protein-phycocyanobilin linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01459">
        <property type="entry name" value="Chrphore_lyase_CpxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018536">
        <property type="entry name" value="CpcS/CpeS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09367">
        <property type="entry name" value="CpeS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="179" mass="20071" checksum="641D76C08CB605DF" modified="2018-01-31" version="1">MFMNINQFVENSLGQWRSQRSAHHLTFRHFEAIESVIDIVAVSPDDTAVIDLCKSYNIDPTQAVSPFQMTWEGHTDWDENAEMKGSCILVPIPDRTIPNRGKLLRDQGYAETIPAAADYHFTDDGTFVLLTSYDNAAAEEKIWFANPNLRFRVSLIKTSQGSGVVTASFSSEIRSLPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2D8</accession>
    <name>A0A2G4F2D8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55943">
        <property type="protein sequence ID" value="PHX55943"/>
        <property type="gene ID" value="CP500_008200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="149"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="407" mass="47144" checksum="474A24D7274134B4" modified="2018-01-31" version="1">MVRGNYDRQKPYLSNPQISKPIAEIYADLDAFSWEIFEDQTHRFDTVSFYVLIPPLFYEGKFIKGIYFSEAVELINKLFPQLSSVFHSFTYSPGASYSWAPVADAYSSLYKNPQRDKWFRETYADRAHKPIIPLQDTDFINEYLISPRNVPEKDIDLLAVARISEEKNLPTIAKALKVYRQKYPQKPIKLTVVTGHDFDASNLKTLDEYALNEWRQIETILTNPSDYINLLPRVDYYQEIPNYYSRAQAFVLGSLLEGKNRGITEAMSCNVPVICFQEFNQYARGDSPVFPEGAGLYAKFDPESLADTIYTVLENRTEFKPRYQYLKHCGRKNFFNTCIDSFPYYQHNIPDYKAGDAINNLWLDLAVQQNYQVSLNSFLYGGSHLSHLRGINTIQQHLGELTKFIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2F0</accession>
    <name>A0A2G4F2F0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe-S cluster assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55926">
        <property type="protein sequence ID" value="PHX55926"/>
        <property type="gene ID" value="CP500_008100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="131"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="480" mass="53062" checksum="9D15D0E4F3469E1B" modified="2018-01-31" version="1">MSSTTAQTLVNQPYKYGFVTDIESDTIPRGLSEDVVRLISSKKNEPEFLLQFRLKAYRKWLTMTEPTWPHVNYPAIDYQNIIYYSAPKQKPKKLNSLDEVDPTLLETFEKLGIPLSEQRRLGNVAVDVVFDSVSIATTFREKLAKDGVIFCSITEAIKDYPELIEKYLGTVVPVGDNFFAALNSAVFTDGSFVYIPKGVKCPMELSTYFRINNEDSGQFERTLIIAEENSSVSYLEGCTAPMFDTNQLHAAVVELVTMDNADIKYSTVQNWYAGDANGKGGIYNFVTKRGLCQGVNSKISWTQVETGSAITWKYPSCVLVGDNSVGEFYSVALTNNKQQADTGTKMIHVGKNTRSTIISKGISAGNSANSYRGLVKMGPSAKGARNYSQCDSMLIGDNAQANTFPYIQVQNHTAKVEHEASTSKIGEEQLFFFAQRGISAENAISMMISGFCKDVFNQLPMEFAAEADKLLSLKLEGSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2G7</accession>
    <name>A0A2G4F2G7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_008235</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55950">
        <property type="protein sequence ID" value="PHX55950"/>
        <property type="gene ID" value="CP500_008235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="14"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="270" mass="30918" checksum="759EFAF4CCABC296" modified="2018-01-31" version="1">MLTNAIGTQEPTLLEFDRVGLQYEVDGQPRRIIDEISLSIAQGEFVSFVGPSGCGKTSILRMVSGLSPAPIGEIRIRDKKITKPLKNVGIAFQNPVLLPWRNTLDNVLLPLEVVQPYKRESKDPKRREMFVRQAQELLATVGLQDFQKQFPWQLSGGMRQRASLCRGLIHQPEILLLDEPFGALDAFTREEMWVMLQELWMRVKCVCILITHDLREAVFLSDTVYVMGPRPSSIVYKVKVNLPRPTNLDMMMSDDFNHIVAELRRHIHRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2H2</accession>
    <name>A0A2G4F2H2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">rsmI</name>
        <name evidence="8" type="ORF">CP500_008195</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55942">
        <property type="protein sequence ID" value="PHX55942"/>
        <property type="gene ID" value="CP500_008195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="9"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="293" mass="32400" checksum="1BF55C52797B7856" modified="2018-01-31" version="1">MQANPNTGTLYIVGTPIGNLEDMTFRAIKILQAADYIAAEDTRHTGKLLHHFQIKTPQISYHEHNRHQRLPELIDKLLLGKSIALVTDAGMPGISDPGYELVKACADANINIIPIPGACACIVGISASGLPTDRFVFEGFLPAKGQERQLSLEALQIESRTIILYESPHRLRQTLQDLANSLGSDRQIVLARELTKMHEEFWRGSIESAIELYTTHEPKGEFTLIIAGIQTDAPIFSEDAIKAELQALIETGVTRSQASRQLAQQTSLPRRQIYQLALTIGDSESLEQPLDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2I0</accession>
    <name>A0A2G4F2I0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55956">
        <property type="protein sequence ID" value="PHX55956"/>
        <property type="gene ID" value="CP500_008130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="307" mass="35140" checksum="CCB2B8EAB66FBACC" modified="2018-01-31" version="1">MIFINPKTDYAFKKIFGSSESKDILISFLNALIYDGNPTIEDLEIINPNLPPKIEGLKDSYLDVKAKLQDGTLVIIEMQVLNVESFGKRVFYNAAKTYAFQLQAAQAYRLLKPVIALTITDFEMFPNSEDFISRFVLKEVDKNFTYPENELDLVFVELPKFMKGEEQLETLADKWIYFMKNARSLTSVPEIMDSVPEIHQAFDIANQVKLSREEVEEFDRREQFIYDQQGAIIKAVREGIEQGIEQGIEQGREQGREEGIEEGREEGMKFEKLAIAQRLLSQLDNITISQVTGLSVEEVQNLRAANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2M7</accession>
    <name>A0A2G4F2M7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Twin-arginine translocation pathway signal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the CmpA/NrtA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56006">
        <property type="protein sequence ID" value="PHX56006"/>
        <property type="gene ID" value="CP500_007570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13553">
        <property type="entry name" value="PBP2_NrtA_CpmA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044527">
        <property type="entry name" value="NrtA/CpmA_ABC-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="476" mass="53248" checksum="F731A02842C199CB" modified="2018-01-31" version="1">MSDSFFQEWKRREFLQGMGSAAVGLALSGCGVSADRSAKGLTEEALAVTPVVNSQTLEKPNLTIGYVPVNDCAPFAIAWKKGFFRKYGLNVTLNREASWATSRDGVIFGRLDASPVVSGAVTNARIGAEGARHAPLCAAMTIHRHGNAMTMNKAMWDFGLRPWHEYNGNIEEFGKQLRAFFDSQPAEKKVWAVVLSSAIYEYFVRYISAAAGVDPFKEFRVIIVPPPQMVTNMRMGEMQAYMVAEPWNTRAIQGNMGVGFTFAQGKEVWQGHPDRVLGVMESFIDENPKTYYSLVKAMVEACQYCSKPENRSEIALLLTERSFTGAKPKTGAIDKFTRPGIVGDYNYGGFDGKDRTVRSEDTTIFFDIPANLPQISGNHSTFMWQSHSIWLITQAARWGHIKEVPKNAEELAKQAWRTDLYRKIVAEMGINCPLEDYKIEPAEVFIDKKAFDPSNPVGYLKSFEIRANRPKSFFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2P4</accession>
    <name>A0A2G4F2P4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55727">
        <property type="protein sequence ID" value="PHX55727"/>
        <property type="gene ID" value="CP500_009205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="124" mass="14423" checksum="9C33A7CF94BE94A8" modified="2018-01-31" version="1">MTIPQLKPADEKESKVYAPFFPEQRRKSLPYAIALYKLKSLEGARKIEGGDEIPFVASWNISSLPIDLTRCRVLFDGNAELSYEVTMQSSDFVNCLIEVLMIFRRSRTVDFSKVFYRKLMRMDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F300</accession>
    <name>A0A2G4F300_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56141">
        <property type="protein sequence ID" value="PHX56141"/>
        <property type="gene ID" value="CP500_007100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="82"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="280" mass="31842" checksum="007DB04C2CCBDC85" modified="2018-01-31" version="1">MATIEDFRQLSDSDWLTLLIQSVKGQTVQGLDFPKFPQDTIQTNFVGSCGERALKEAYLFYDFLKREALKSGVSIKKNSTILDFGTGWGRFLRFFWKDVSEKGLNGVDVDPVMIDLCRTLGVPGNLQTIQPLGFLPYEDSSIDVILAYSVFTHLPENVHLNWMQEFKRVVRPGGIVAMTIEPRRFLEFVAELKNKTPENNWHAALQKFSDYAEQAIPLYDSGQLVYLPTGGGAFREPSVYGDAVCPISFLEKNWMPEFSIRSHIDDPKQFWQAAVLLQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F301</accession>
    <name>A0A2G4F301_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbonate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56129">
        <property type="protein sequence ID" value="PHX56129"/>
        <property type="gene ID" value="CP500_007000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="237" mass="25121" checksum="3002430E0BAA78CF" modified="2018-01-31" version="1">MNLNDKKVNLSRRNSLKFVAGAIGTGILAARVGADVVAPEPAIAQNDLTPDAALKQLMDGNKRFVDRKRQTPNQDFVRITEVAKSQKPFAAILGCADSRFPPEIIFDRGFGDLFVCRVAGNVATPEEIGSLEYGTLVLGAKVLVVIGHERCGAVDATIKGAEVPGQIGSLLAAIKPAVESSKDKTGDRLENACKANVVLQANKLKASPVISKLIAENKLKIVGGYYDLDTGAVNILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F332</accession>
    <name>A0A2G4F332_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56170">
        <property type="protein sequence ID" value="PHX56170"/>
        <property type="gene ID" value="CP500_006920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8516" checksum="701297B747537C21" modified="2018-01-31" version="1">MWRVTINCSAADWDIHSKAFKAIAEKYPGTPLSSKKMKGDGQRIMEYQVENVNDAEDFMEECSTLDGFMATFESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F376</accession>
    <name>A0A2G4F376_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56198">
        <property type="protein sequence ID" value="PHX56198"/>
        <property type="gene ID" value="CP500_006730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="2"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="13027" checksum="8C7F5BAF132A0C59" modified="2018-01-31" version="1">MLLDEDSQAKYLVNLLQAAGHDVATVNTLDLMNRPDSVVLQAARENERVVLTRNCDDFQELHQANPEHSGILAVYQDSEASKNMSYQAIVKAIDNLETAEYDLKNQFVVLNQWSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3E3</accession>
    <name>A0A2G4F3E3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF937 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56241">
        <property type="protein sequence ID" value="PHX56241"/>
        <property type="gene ID" value="CP500_006425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="176" mass="18278" checksum="AB38944FD1601136" modified="2018-01-31" version="1">MGLFDQILGAIDNPNQQASPNQLGSILGAVEQLSGNQGVDAGTTQLAMSVLGGYVRSALQDVRSESGDAQAQQVVNQFSGTNPNPDAVQSLFGGGQLTQIVQDIAQKTGLNNSTVQAMIPVLVPLVLNLLQTGSNTQNPAQGGNSVLNAFLDADGDGDVDITDTMSMASRFFNQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3M5</accession>
    <name>A0A2G4F3M5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56359">
        <property type="protein sequence ID" value="PHX56359"/>
        <property type="gene ID" value="CP500_005815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="13012" checksum="5F3DA0DEC0ED43AE" modified="2018-01-31" version="1">MGDRADPQARRGLKSLSHSQSRLKPTEQSDSTMGDRADPQARRGLKSLSHSQSRLKPTEQSDSTMGDRADPQARRGLKSPSHSKSRLKPTEQPDLTIADFSPLSEDLSYETGISIPVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3N8</accession>
    <name>A0A2G4F3N8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MoxR family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56380">
        <property type="protein sequence ID" value="PHX56380"/>
        <property type="gene ID" value="CP500_005550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="35"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="228"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="302" mass="33204" checksum="CD8ADEBF1F129733" modified="2018-01-31" version="1">MRENIDRLKQNLGKTIVGKADAIRLVIVALLSGGHALLEDVPGVGKTLLAKSLARSIDGKFQRIQCTPDLLPTDITGTNIWNPSSGKFEFLPGPVFANVLLADEINRATPRTQSALLEVMEEKQVTVDGVSRTVPTPFFVIATQNPIEYQGTFPLPEAQMDRFTLSLTLGYPGELEELQMLERLSDSFAVEDLQPCISLEEVQELRRLCAAVKVEGHLKQYIVNLVRSTREDEEITLGVSPRGAVSLHRASQALAFISGRDYALPDDVKSLAPHVLSHRLIPAGGRRAKTIVDRLLREVAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3R8</accession>
    <name>A0A2G4F3R8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56402">
        <property type="protein sequence ID" value="PHX56402"/>
        <property type="gene ID" value="CP500_005680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="274" mass="31046" checksum="D6A049CA65141AEE" modified="2018-01-31" version="1">MKTKIEQFSQKWLSLLVSGIIATAALAGVVTIQSNQQLGGISAMENEGSKPAPAISAVTFKQSEQQERLRLKMLKALPTFGFDNLVADWTFLKFLQYFGDDEARDVTGYSLSPDYFDIITQRDPRRVEIYPFLSVAISFYQAKPEIAVQLMERGTSALSPQIDPQAWMVWRNKGLDELLLLGDIPESIRSHEMAADWVEGNPEGKQFAPIFRTTAEFLRRDPDSVQVRFMAWSSVYAQTKDKFVRMRAKQALVKLGAQVRKDKDGKESFILPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F413</accession>
    <name>A0A2G4F413_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56524">
        <property type="protein sequence ID" value="PHX56524"/>
        <property type="gene ID" value="CP500_005075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="207" mass="23332" checksum="9044A0FC2F7F2987" modified="2018-01-31" version="1">MRTSLEMRWFCKGMLPKAIGQWFGSESLGGYLSPPEEREDLYLLIPGCDYLGVKLRGKNLQVKWRQAEFGAMQFGNRWEGKAEKWLKWICADTMGPLSADLIATGKWVKVKKKRAQRLYQVSAPGALMSVPVEAPIPQGCIVEINQLNINETPSWTLGFEAFGSESFLTESLQTVANWTSKNYQAQRLTTEDSSSYPIWLASLSTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F459</accession>
    <name>A0A2G4F459_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Maltooligosyl trehalose synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_004690</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56550">
        <property type="protein sequence ID" value="PHX56550"/>
        <property type="gene ID" value="CP500_004690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="614"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="648"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="678"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="760"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="35"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="142"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="217"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="256"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="786" mass="87174" checksum="71BBEC403E0A0E9E" modified="2018-01-31" version="1">MTNNIGQPTALSDRPYLVLNSQGQVLQLELRQQQHILGRDRTRADLIVPEPWRAVSGIHAVFRQIGDNYWIYDGDGQRPSTNGLFVDRTRITPNDGYCLKNGAEIKIGLDPKNQVLLTYFNPKANQIVLPNKQSISLKNRSVLLGRDPNASLQLDSPLVSRRHATIDQDSRGNYILRDYSVNGVFVNGQRVTNSVQLSEGDAIRIGPFTLTYRSGELEMQDEGHQIRLDADCLVIPKRLDRITLAIEPGQFVALVGGSGAGKSTLMRTLLGIEKTTSGVVYLNGDNLRKNFNIYRNQIGYVPQDDIIHADLQVEEVLNYAAKLRLPPDTNVKQVVTKTLEDIEMTHRRNALVKELSGGQRKRVSIGVELLADPKLFFLDEPTSGLDPGLDKKMMQLLRKLANQGRTVILVTHATANITMCDRIVFMGRGGRLCYFGPPTVALDFFDVKTGDFADIYNELETSEINVQSWADKFYNSPYYQQYIVNHFSAGNPEGKTPTAPPKPKSVSFFQQLVLLAQRYFKLISRDIVNLSLALLTAPIGICLLRLAVRDKDPLIGAPEATLAPLALRVLFVFTCAAIWVGLATSLQEIVKESAIYLRERLVNLGLFAYLGSKFFILSGLALLQTILMVGVILIAFKHPEPSLISWTLGVSITTFLTLLSCVSLGLVVSAIVKNSSQANSALPLLLLPQIIFSGVLFKMEGAASKFSWLMLSRWSVGAYGSLVNVNAMVPAATKLPDGSTLPQPFEPTPVYDPTWGNLSLNWGILCVHILVYLMLTLWLQKRKDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F468</accession>
    <name>A0A2G4F468_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56538">
        <property type="protein sequence ID" value="PHX56538"/>
        <property type="gene ID" value="CP500_004625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="608" mass="64320" checksum="039B193ED56226EC" modified="2018-01-31" version="1">MSQYFSGQNLRGRNFQGQNLTGAKFIGADIRGANFTNAILREADFTRAQAGLQRRWTIFLVTISLFLSVISGLILILASFWVAFFFTSDNIKQYTILPGVVVLIVLAILFIATIRQGLAAGAAAVPATATGAAAVAVAATGTGTGAAVVTGAVAGAGAAAATGAAAVVAVAVAGAVAGAVAGAVAGAVAVAVAVAVAVAGLGAYIAWRALAGDEKHAFVSKIAIVFAATGGTSFRNADLTDANFTEATLKSTDFRTANLTRTCFRNTKKLDRARVGKSILADTHIRELLVTGNGYKKSYVGANLQGANLTGVNLNEANLKQANLSEATLHQANLQFANLTETQALATDFTAAYFTGACLEAWNIDATTKLDRADCRFVYLLEYPKPGTDDRERRPHHISKCFEPGDFEKLYKKIMTTVEILLKDGVNPEAFTAAFQKLMQEFPDITRDSIQGIEKKENDVLLTLKVPEGTDKGKIEQTWDEGYQAGLQAQSQAEQLKSKDEIIAIERHHNRVFQDFVKGVFSQYLINPSTVPQPSNPIININNQSTAENKVASDNIDQSRKAEISGGTVNATGAGSLSLGDNDGTTANTIEQLSDSAVSAALEEDRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F473</accession>
    <name>A0A2G4F473_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Malto-oligosyltrehalose synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">treY</name>
        <name evidence="3" type="ORF">CP500_004665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56584">
        <property type="protein sequence ID" value="PHX56584"/>
        <property type="gene ID" value="CP500_004665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11336">
        <property type="entry name" value="AmyAc_MTSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012767">
        <property type="entry name" value="Trehalose_TreY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02401">
        <property type="entry name" value="trehalose_TreY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="4"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="930" mass="108135" checksum="A4540E8583544E1C" modified="2018-01-31" version="1">MRIPTATYRIQFHTGFNFEAARQIISYLKDLGITDLYASPIFKARKGSSHGYDVVDSNQLNPELGTSENFEALTDEIQNKKMGWLQDIVPNHMAYDTQNLLLLDVLEHGPDSDYFDYFDIEWDHGYEHLRGRVLAPLLGNFYGECLENGEIQLKYSDIGLSINYYGLKLPVKIESYAKFISNNLGYLGRELGRRHPDFVKFLGILYLIKNTPSETKGQERYDQIAFVKALLWELYNQNPMVQEFIDENINFFNGEKGNSESFNLLDDLLSEQFYRLAFWKVGAEEINYRRFFTVNELISVKVEDIKVFHKNHALIFELIEEGKITGLRIDHIDGLYDPTEYLKRLRHQIGDIYITVEKILEHKEDLPSYWPIEGTSGYDFLNYVNGIFCRCDREQQFSEIYHRFTRLNVPYEQLFIDKKRLILEKNLAGDVDNLAQLLKNISGQSRQGNDFTRHGLEKALAAILTIFPVYRTYINQEGLRESDRTYVKYAIAKAKEQVPLLLKELNFIQTVLLLEAEEILTAEQKEQRRHFVMKLQQLTGPLMAKGIEDTLLYVYYRLLSLNEVGGNPSQFGVSLADFHEFNQHQQAVWPHKMNATTTHDTKRGEDVRARINVLSEIPDEWEQQVRSWRELNSAKKVNLVNRMVPDTNDEYFFYQTLIGSFPFEEIANIDFIQRMKDYVIKAVREAKVHTAWLRPDNDYENGFMTFVDHVLEPGEQNQFLKNFMPFWKKVADYGILNSLSQTLLKITAPGVPDIYQGTEFWDLSHVDPDNRRPVDFQRRIKVLGEIKQQAQTDILQLVEELISTREDARIKLFLTARVLEARKQYLQVFQSGNYQPLEVVGTFKENIVAFARSYEDTTVIVIAPRFLTGIVKPEEMPIGKKVWQDTKLELSDEMPSVWQDAITNQMVESNSQLAIGEALNYFPAALLISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4F5</accession>
    <name>A0A2G4F4F5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4058 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56591">
        <property type="protein sequence ID" value="PHX56591"/>
        <property type="gene ID" value="CP500_004435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025132">
        <property type="entry name" value="DUF4058"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13267">
        <property type="entry name" value="DUF4058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="262" mass="30282" checksum="839298C21368E3E9" modified="2018-01-31" version="1">MPSPFPGMDPYLEHPELWPALHHLLISEIFRFLSPQLRPKYLVSLEVRIYETADDNLSIGIPDVNVIQPKTKTELITSNVAVAARPTQPLIVNIPMPYQVREGYLEIRERGNEELITVIEILSPSNKRTGKGRQMYEEKREEILSSRTHLIEIDLLRRGRKMPVIGNDIESHYSILVCRGNRRPKADLYAFNVQNPMPAFPLPLRSGDIEPIINLQELFTQIYDIASYDLKIDYRNWEVIPALSEADTIWADGWLRDRGLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4L5</accession>
    <name>A0A2G4F4L5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_003685</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56724">
        <property type="protein sequence ID" value="PHX56724"/>
        <property type="gene ID" value="CP500_003685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="123"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="123"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="226" mass="25495" checksum="65933859A761597A" modified="2018-01-31" version="1">MNVLYVEDEAKIANFVCIGLKEQGFVVDYCDNGNDGYDRAMDNQYDAIVLDIVLPGKDGLSILKLLRKAGRNVPVILLTARNELDDRIEGLHLGADDYLAKPFFVEELIARIYAVVRRADGGQNTIAVGPVKLDRILREVTCDSHAVELTTREFNLLEYLMRSPGRVLTRTQILEHIWGYDFNPNTNVVDVCIQRIRKKIEPIGGTGWIESVRGVGYRFRKPDSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4P3</accession>
    <name>A0A2G4F4P3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_003665</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56720">
        <property type="protein sequence ID" value="PHX56720"/>
        <property type="gene ID" value="CP500_003665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="SSF161084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="50" mass="5836" checksum="2FA796005A550D65" modified="2018-01-31" version="1">MYFSLFVSSRIIHTVAYIRGLQPLRNIVYQLGILVMFALCSHIVWTVFMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4R3</accession>
    <name>A0A2G4F4R3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sulfate ABC transporter permease subunit CysW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysW</name>
        <name evidence="11" type="ORF">CP500_003755</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56736">
        <property type="protein sequence ID" value="PHX56736"/>
        <property type="gene ID" value="CP500_003755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015419">
        <property type="term" value="F:ABC-type sulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011866">
        <property type="entry name" value="CysW_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005667">
        <property type="entry name" value="Sulph_transpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406">
        <property type="entry name" value="PTHR30406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406:SF1">
        <property type="entry name" value="PTHR30406:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00969">
        <property type="entry name" value="3a0106s02"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02140">
        <property type="entry name" value="permease_CysW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0764">Sulfate transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="75"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="291" mass="31655" checksum="AB6A3F65E9BC2BF6" modified="2018-01-31" version="1">MTAKINSSADYKFPPAGSSRIQEKAWVKPTLIGIAIGYLALILFIPTINVFYQAFKKGVEPFFANLTSPDFLSAAQLTLLITLIVVPVNTVFGLCAAWVIGRNKFPGRTLLISILDVPFAISPVVAGLMIVLLYGRLGWFGPWLEAADIKVIFAFPGMVLATAFVTLPFVAREVIPVLEEVGTDQEEAAKTLGANDWQIFWNVTLPSIRWGLLYGVILTNARAMGEFGAVSVVSGNIAKKTQTLPLFVEDAYKQYATQSAFSAAVVLGLLAVVTLVLKEILERKTSIKEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4X8</accession>
    <name>A0A2G4F4X8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nusG</name>
        <name evidence="10" type="ORF">CP500_002975</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56853">
        <property type="protein sequence ID" value="PHX56853"/>
        <property type="gene ID" value="CP500_002975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015869">
        <property type="entry name" value="Transcrpt_antiterm_NusG_bac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01014">
        <property type="entry name" value="NUSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="8">
        <location>
            <begin position="27"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="9">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="212" mass="23896" checksum="146215A1BB8676C5" modified="2018-01-31" version="1">MTFASEESEYSTEATAGKGSPEVPEINARWYAVQVASGCEKRVKANLEQRIQTLDVADRIVQVEIPQTPAIKVGKDGSRRQSDEKIFPGYVLIRMFMNEDTWQVIKNTPNVINFVGAEQKRRYGRGRGHVKPLPLSHSEVERIFRNAQESEPVVKVSMAIGDHVVVLSGPFKDFEGDVIEVSPERNKLKVLLSIFGRDTPVELEFNQVQKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5M7</accession>
    <name>A0A2G4F5M7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma regulatory factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57056">
        <property type="protein sequence ID" value="PHX57056"/>
        <property type="gene ID" value="CP500_001875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016781">
        <property type="entry name" value="Anti-sigma_regulat_PmgA_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020906">
        <property type="entry name" value="Anti_s_fact_PmgA_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="36"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="158" mass="17831" checksum="D23DB43F8743B9B5" modified="2018-01-31" version="1">MIAISARPVGRNWITISFASTLYLCPVLDLLLAEVPDHWEAELRLGLQEALVNAAKHGNKLDPSKTVGVRFSIVQNQYWWVISDEGSGFDAPCSCNFSTDNCDSHLADKSELPDVENECGRGLFILYQIFDRVEWNSQGTELRVCKEVPSRSRLPRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5N1</accession>
    <name>A0A2G4F5N1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">map</name>
        <name evidence="5" type="ORF">CP500_002360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57048">
        <property type="protein sequence ID" value="PHX57048"/>
        <property type="gene ID" value="CP500_002360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="15"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="253" mass="27542" checksum="0C2742366D02BE02" modified="2018-01-31" version="1">MATERLVLLSSREIDKMRQAGRLAAELLLHLEPMVKPGVSTLAINDEAERWTLAHGAKSAPLGYKGFPKSLCASVNQVVCHGIPNAKQILREGDIINIDVTPLVDGYHGDTSKTFFVGKPSPVAKRLVEVTEECLRRGIAEVKPGARTGDIGAAIQQYAEAQGFSVVRNFAGHGVHRVFHTEPEILHYGKRGTGKKLRQGMVFTIEPMINEGTWEVEILADGWTAVTQDGKLSAQFEHTLAVTDSGVQILTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5W5</accession>
    <name>A0A2G4F5W5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplP</name>
        <name evidence="5" type="synonym">rpl16</name>
        <name evidence="9" type="ORF">CP500_001780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57150">
        <property type="protein sequence ID" value="PHX57150"/>
        <property type="gene ID" value="CP500_001780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="8">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="15833" checksum="9EE1A874B480F5A1" modified="2018-01-31" version="1">MLSPKRTKFRKQQRGRMCGVATRGNTVSFGDFALQAIEPAWITSRQIEAGRRAMTRYIRRGGKIWIRIFPDKPVTQRAAETRMGSGKGSPEFWVAVVKPGRVMFEIGGVTEEIAREAMRLADFKLPIKTKFITREDEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F659</accession>
    <name>A0A2G4F659_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57229">
        <property type="protein sequence ID" value="PHX57229"/>
        <property type="gene ID" value="CP500_000880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="43"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="20141" checksum="FD1AECBE9E557F99" modified="2018-01-31" version="1">MSDLIPGYSLRSGSGLDRAQLVKFMHRTYGELYPDGEFGHLAQTVEQYFANQTPLWFVECQKNREQEKAILSALPSSDPSLKSQVHNLKSTIGCLWLGNAIDQGTGERHAHIFLLYVAPEHRRLGIGRYLVIHAENWAKKRGDRQIGLQVFLNNQPALNLYQKLGYQSHSVSMIKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6B7</accession>
    <name>A0A2G4F6B7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57289">
        <property type="protein sequence ID" value="PHX57289"/>
        <property type="gene ID" value="CP500_000845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="221" mass="25680" checksum="C87E56285AD34E22" modified="2018-01-31" version="1">MSPLSFSYIPEISIIVPTYNRAKYLSDCINSVLNQTFKDWELLIIDDGSQDDTFDIINPFLEKHENIRYFKHKNRKMGFSRNAGIQASFGKYITFLDSDDQYKPNHLESRLEYMKANPEVDCLAGGFETDGDIFVADYYQPGKLINAEECVMGATFFLKRHVLFELKGFQNISYGEDTDLWERAQKKFKTVKIFQPRTYIYTRAEDSVSKSFTANIDLNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6B8</accession>
    <name>A0A2G4F6B8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57300">
        <property type="protein sequence ID" value="PHX57300"/>
        <property type="gene ID" value="CP500_000505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="31106" checksum="88532EA09F1CB9B0" modified="2018-01-31" version="1">MTERDEQLRRLIQGVLGPSGARSQDMERLLARVPTLPRIMKSPHPDYLEALNKTLEYVRVNIKVFIIKFKVDIDREHPENLRTKFVIWFNGHLKYRILDLYRTKPLPLSLDAPVFSDIFYEKNSFLETLPDVGFNAPLLDGIESLIEKSQTDRTQRKALILELYIEQDYLQKLSGCHPKICLTCNCQTLLKAMYLTSPGERVSLKEGKIAAEKKISWRSLAKSFDLNEQTLHTHWRNRCRPLLHEILADIEKNLVEYERKFLGEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6F1</accession>
    <name>A0A2G4F6F1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57330">
        <property type="protein sequence ID" value="PHX57330"/>
        <property type="gene ID" value="CP500_000690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="7"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="133" mass="15176" checksum="D87C5CF4552DD15E" modified="2018-01-31" version="1">MTYISATLRRYIEERASYGCEYCLLGISLSFFPHEVDHIIAVKHGGTTDADNLALACWRCNRYKGTDLGSFDPQTSAFSFLFNPRTQNWPEHFTLDNGRIIGLTPEGRTTVNLLQLNNDERLAERRRSLSNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6H1</accession>
    <name>A0A2G4F6H1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57350">
        <property type="protein sequence ID" value="PHX57350"/>
        <property type="gene ID" value="CP500_000795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="309"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="492" mass="53941" checksum="AD46862FEFA89179" modified="2018-01-31" version="1">MTQQNILELAKQGDAKAIALLLNRQLQPKGITAAASLKDGYLQVMLEATEAPSQQVLAGWVSKSIAGLGAASIEKVKVYGRQTGSKVPAWSQEFEVAGQKLPVANVTQGRASSSENTESNQLSLKERAKLGDVEAIASLLNLPLQNKGITATASLQDGCLQVMLEGDRVPDEEASIRIVRRELTNLKAGAIASVKVYGQQVGEDFPAWNREFELVARASQSSHNLGVNTTNQLSANNSYAETTQEPSLIQILNETSTELLSDNQWNAAFIILSVIAFFMLFVNFTLAVILAIAASIAYVKYQNTPTGKAAAAKRQLEALQKAEEALQKAEEAEQERLRQEEQKRILIEAAQSEAKLLTTNLAHTALDEFRKVNARTSIGVSYTDLPGVIAPAKFATQKFEKSKDYKVCPYLSQLISNNMLYYEITQECFQKKVTYKPLSSQFKAIIQTDFPELKGVIISLSLDLVISTIWQKADLYSDEIEAILESSDNLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6H2</accession>
    <name>A0A2G4F6H2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57087">
        <property type="protein sequence ID" value="PHX57087"/>
        <property type="gene ID" value="CP500_002065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="13906" checksum="2802B08CD2E0B1CD" modified="2018-01-31" version="1">MQLEDYFNFLRPDDIRLKGSRIGIETILYEYLFRARTPEEIANVYTSLTLEQVYATILYYLHNKEAVGKYITEWLEWGDKMREEQRRNPRPVYEKIRKLRAARDAMRKADGNPVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6N8</accession>
    <name>A0A2G4F6N8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2079 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57409">
        <property type="protein sequence ID" value="PHX57409"/>
        <property type="gene ID" value="CP500_000265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018650">
        <property type="entry name" value="STSV1_Orf64"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09852">
        <property type="entry name" value="DUF2079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="549" mass="62350" checksum="EF6702C950415CBE" modified="2018-01-31" version="1">MKLKPLDYWQNQTGLRQAIIIAATFFTVVLTFSIINYESFLITYDHGLFNQVFWNSVHGKLFQSSLSSAASSASLIDRQLSYPSYIHLGQHFVIDFLLWMPIYALFPSPITLIVLQVALIAAAGIVLYFLARHYLSVPISVMIVASYYGANGVIGPTLGNFYEHCQIPLFVFSLLLALEKQRWVLFWIFAALTLGTREDVGITLFGIGVYLIFSRRYPRTGMALCAISFSYVVLITTTVMPMFSVDSSRLYLASYFRKFVKTEAPSTLELLWAIISQPQIIIEVLFTNFSRRILYLLGHCLPLGFIPVITPSAWIMTVFPLSVLLLQVFNQSATSINTRYTLAVIPGLFYGTILWWSQHQEKFKPRLHRFWIGCIGLSMLLTYTSNPHRALYFISPYSIQPWVYQSLSAQLDHAADLKTVFNSIPKDASVSTSSYIVSHLSGRRNIIRLEVMQMKDENGKIVDVDYGLLDLWQLREDNLKGPIDRGRVRGGVRFADEALRQGTYGVAQVLDGVVLIQKGITSKPEVLAAWLKLRQEIEPLMQKKQKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Y0</accession>
    <name>A0A2G4F6Y0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenosine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57337">
        <property type="protein sequence ID" value="PHX57337"/>
        <property type="gene ID" value="CP500_000725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="60"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="338" mass="36216" checksum="538F391D66BCD7DE" modified="2018-01-31" version="1">MTENKINSGSIDVFGVGNALVDILALVEDDFVIKHGLNRGGMTLMDSETQGGILHDLEHTSLQMRSGGSAANTMIGVAQSGGKCYYSGKVAKDTNGEFYRQDLLEAGIDFNVHPATESNGPTGTCVVLTTPDAERTMCTNLGVSASLAMTDIDVDRLSHCKYSYVEGYLWSTPDPRKASIETMEQSKRLGVKVAFTFSDGFLVAQFADDFHKVVSEYCDAIFCNADEVRSFFKEESLEECARKMSEISDLAFITNGDKGCIVVENKQIVDVAGFPVKAIDTVGAGDAFAGGVLFGLTNGLSSAQAARWGNYLASMVVQIHGPRLEGSQAHLLSQVISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUG9</accession>
    <name>A0A2G4EUG9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000252">
        <property type="protein sequence ID" value="PHX53174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53174">
        <property type="protein sequence ID" value="PHX53174"/>
        <property type="gene ID" value="CP500_022915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="143" mass="16711" checksum="A804016959862A67" modified="2018-01-31" version="1">MESGQWTLEGSWIERNGVPITVKGKTLVSWNRTDWFNMVTKLVFPGGDREEIILQYRGHLNSDERQYTFVLQHSELGRVEGEGWIAPQSIVQRYWVLGDERQRRTGFDTLHRVDSNRYYHSSGIMSGHYLTSTMEATLERQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUY9</accession>
    <name>A0A2G4EUY9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53353">
        <property type="protein sequence ID" value="PHX53353"/>
        <property type="gene ID" value="CP500_021955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014056">
        <property type="entry name" value="Addiction_killer_pred"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41791">
        <property type="entry name" value="PTHR41791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028744">
        <property type="entry name" value="Addict_mod_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02683">
        <property type="entry name" value="upstrm_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="12550" checksum="9C71B978CDCB566A" modified="2018-01-31" version="1">MPEVQPREIQRYIASDGRVPYDQWFDSLRDINAQAKIISRLNRIADGNLGDYRSVGEGVCELKINYGPGYRIYFGQIGITIVLLICGGDKSTQDRDIRQAKEYWTNYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUZ1</accession>
    <name>A0A2G4EUZ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydropteroate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">folP</name>
        <name evidence="2" type="ORF">CP500_022520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000230">
        <property type="protein sequence ID" value="PHX53250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53250">
        <property type="protein sequence ID" value="PHX53250"/>
        <property type="gene ID" value="CP500_022520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pterin-binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="28617" checksum="EA295928DEB85F51" modified="2018-01-31" version="1">MGVLNITPDSFSDGGDFNTIESALAQAENMVKYGVDIIDIGGQSTRPGAAEISLAEEIDRVVPVVEMLRKKADTFADIPISIDTTRAPVAKVAIEAGADIINDISGATFDPEMLSTVAKLAVPIILMHLRGTPQTMQTLTDYRDLIGEIGEFLQSRIAAAVAAGIDKSQIIIDPGIGFAKTYEQNLEILRELPKFRSLNCPILVGVSRKSFIGQILNQPLAKQRVWGTAAACTGAIANSADILRVHDVREMHDVCQVADAIFRNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVD2</accession>
    <name>A0A2G4EVD2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000190">
        <property type="protein sequence ID" value="PHX53491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53491">
        <property type="protein sequence ID" value="PHX53491"/>
        <property type="gene ID" value="CP500_021225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="26"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="18195" checksum="362D67A555EA78A9" modified="2018-01-31" version="1">MIKLTLLHPLQSIPVRSWIFEDEQVVSIGRSTESHVVLFSAVVSRRHIELRRTGTRWELINLGTNGTYLDGKPIARIPIVDGLIVHLARSGPKIQINVVSNQSSVQLQQISVNPRDAQVIYAPSEVAQIMTIPIPEPKEIGTSREEDDLTQAENTRYSSEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVD4</accession>
    <name>A0A2G4EVD4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53400">
        <property type="protein sequence ID" value="PHX53400"/>
        <property type="gene ID" value="CP500_021645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10549" checksum="85CB9C75FB9A5FE4" modified="2018-01-31" version="1">MKSSVTKSFRTRLESLPASVQEQADKAYALWQEYPYHPSLQFKRVSQKQPIYSARVSINYRALGLLEADSIYWYWIGAHDEYDELLKRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVD6</accession>
    <name>A0A2G4EVD6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000189">
        <property type="protein sequence ID" value="PHX53495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53495">
        <property type="protein sequence ID" value="PHX53495"/>
        <property type="gene ID" value="CP500_021195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="562" mass="61916" checksum="46A867935C9DEAF4" modified="2018-01-31" version="1">MQTYDVIIIGAGHNGLVCASYLLKAGYTVLLLEKRSVPGGAATTEAVIPELPEFKFNLCAIDHEFIHLGPVVEELELGKYGLEYLECDPVVFCPHPDGKYFLAHKSLEKTCAEIARYSERDAKKYAEYTDYWQRALNAMVPMFNAPPKSIIDIAGNYNIDKLKDLFSVIGSPEKSLDFVRTMMTSAEELLNEWFDEEFLKAPLARLSAELGAPPSQKTIAIGAIMMAMRHNPGMARPRGGTGALVQALLNLVKSYGGVVLTDRHVDKILVDDGRAAGVRVANGTEYRATKGVISNIDAKRLFLLIDDSDVDAADPNLRERLERKIVNNNESILKIDLALNEAPKFDRWNHQDEYLIGSILIADSVKHVEIAHTQPAIGKIPDADPSMYVVVPTMRDPSMAPPGHHTVWIEFFAPYQIENAEGTGLNGTGWTDELKNQVGDRCIDKLAEYAPNIKNAIIGRRVESPAELGERLGAFKGNCYHIDMTLDQMIFFRPLPELANYKTPIEGLYLTGAGTHPGGSISGMPGRNTARVFMHAQQPIAQILADVGHSLKSTAKSVFRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVE3</accession>
    <name>A0A2G4EVE3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53436">
        <property type="protein sequence ID" value="PHX53436"/>
        <property type="gene ID" value="CP500_021480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="13934" checksum="24E833A1693A51C7" modified="2018-01-31" version="1">MLDFNTVTEFSHTYCVAICAFLVPANLLTTLQTVVLTGLNRPRIQVQVSVIAASLCAMTMIFHVFTWFVIGVVMPPTFILLLMAVTCLTINIWAIAHPSSMSQLIGFAVSAFREGFKKKKSMDLMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVH1</accession>
    <name>A0A2G4EVH1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome b6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">petB</name>
        <name evidence="8" type="ORF">CP500_021030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="5">Binds 2 heme groups. One heme group is bound covalently by a single cysteine link, the other one non-covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cellular thylakoid membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">Heme 1 (or BH or b566) is high-potential and absorbs at about 566 nm, and heme 2 (or BL or b562) is low-potential and absorbs at about 562 nm.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome b family. PetB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000183">
        <property type="protein sequence ID" value="PHX53529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53529">
        <property type="protein sequence ID" value="PHX53529"/>
        <property type="gene ID" value="CP500_021030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045158">
        <property type="term" value="F:electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00284">
        <property type="entry name" value="Cytochrome_b_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00633">
        <property type="entry name" value="Cytb6_f_cytb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005797">
        <property type="entry name" value="Cyt_b/b6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023530">
        <property type="entry name" value="Cyt_B6_PetB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19271:SF20">
        <property type="entry name" value="PTHR19271:SF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00033">
        <property type="entry name" value="Cytochrome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51002">
        <property type="entry name" value="CYTB_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_NTER" evidence="7">
        <location>
            <begin position="11"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="222" mass="25165" checksum="1684B7B013C4AA8D" modified="2018-01-31" version="1">MFSKQITESKTYQWFDERLEIQALADDITTKYVPPHVNIFYCLGGVTLVCFLIQFATGFAMTFYYRPTVAEAFSSVQYIMNEVSFGWLIRSIHRWSASMMVLMMILHTFRVYLTGGFKKPRELTWVTGVILAVITVSFGVTGYSLPWDQIGYWAVKIVSGVPEAIPFVGSLLVELLRGGVSVGQGTLSRYYSLHTFVLPWLIAVFMLAHFLMIRKQGISGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVH4</accession>
    <name>A0A2G4EVH4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53440">
        <property type="protein sequence ID" value="PHX53440"/>
        <property type="gene ID" value="CP500_021500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046298">
        <property type="entry name" value="DUF6335"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19861">
        <property type="entry name" value="DUF6335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="141" mass="14881" checksum="F70F1D4A3D095511" modified="2018-01-31" version="1">MGLQKKPSKKAIEKRDNSGDLPQEITESYGTGVIAEPGLSEDGITTLDDSSSEYTSTNSQIVGGDGDVAAAEQESATGEELVGGSAPTPDQDMVDELGAAAGIEMPDGAILHTTNMLEHRDESRWELDPNSAEDAQDRPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVM9</accession>
    <name>A0A2G4EVM9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53591">
        <property type="protein sequence ID" value="PHX53591"/>
        <property type="gene ID" value="CP500_020680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8561" checksum="FB577701F3EE8DB6" modified="2018-01-31" version="1">MQTKTIAIRVNAEVAKIFEAASEEQRRKLEALLSLKLSDATRRKRPLEEVMSEMSRNAQSRGLTPEILDSILFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVR0</accession>
    <name>A0A2G4EVR0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000169">
        <property type="protein sequence ID" value="PHX53632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53632">
        <property type="protein sequence ID" value="PHX53632"/>
        <property type="gene ID" value="CP500_020425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BcrAD_BadFG" evidence="1">
        <location>
            <begin position="6"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="321" mass="33988" checksum="08AD75BAFE7C2DB5" modified="2018-01-31" version="1">MSYVFGIDGGGTKTICLLMDDNQQVLGRGEAGPSNYQTLGIESAKQSIQFAIEQAVISANIKTDSHLNIEAICLGLAGVGRPKDLEIMQFLVQNLQLTNDLPVIISFQPRNIVVCSDSAIALVGGTGYPFGIAVISGTGSIVYGQNRQGTTKRVGGWGYVLGDEGSGYDIAIRGLQAALRCYDGRGDYTTLAEKFQVNLGLNTLEELVEVVYRRGWGVKEIAGLASIVDRTAAEGDRVADEIINGAVSELILATKTVISGLFSQTEEFEIALIGGVWSGEGNCRSRFEVAISAIVPNATVISPRHEPAFGAGLLALNSLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVU9</accession>
    <name>A0A2G4EVU9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000166">
        <property type="protein sequence ID" value="PHX53654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53654">
        <property type="protein sequence ID" value="PHX53654"/>
        <property type="gene ID" value="CP500_020300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06533">
        <property type="entry name" value="Glyco_transf_WecG_TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004629">
        <property type="entry name" value="WecG_TagA_CpsF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34136">
        <property type="entry name" value="PTHR34136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03808">
        <property type="entry name" value="Glyco_tran_WecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00696">
        <property type="entry name" value="wecG_tagA_cpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="253" mass="28870" checksum="289FF265977C33E0" modified="2018-01-31" version="1">MKIVKLLNVSVDNFSITELFERLEDGGGVVFTPNVDHLIKLQHDRDFYEAYNSCDYRVCDSQILMYASRFLGTPIQEKISGSDLFPAFYSYHKDNEHIKIFLLGAAEGVAIQAQEKINLKIGRAIVVAAYSPSFGFEKNPEECEKIIEIINQSGATVLAIGVGAPKQEKWLVKYRHKFTHIKVFLAIGATIDFEAGCKARSPKWMSEVGIEWAYRLLSEPRRLWKRYLIDGLPFFKLIVEQKLGSYKMPFFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVV9</accession>
    <name>A0A2G4EVV9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Allophycocyanin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_020650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cellular thylakoid membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53586">
        <property type="protein sequence ID" value="PHX53586"/>
        <property type="gene ID" value="CP500_020650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000081">
        <property type="entry name" value="Phycocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3 4" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="2 4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="161" mass="17577" checksum="A4E8A1A2B91239F1" modified="2018-01-31" version="1">MSIVTKSIVNADAEARYLSPGELDRIKSFVTSGERRVRIAQILSESRERIVKQAGDQLFQKRPDVVSPGGNAYGEEMTATCLRDLDYYLRLITYGIVAGDITPIEEIGIVGVREMYKSLGTPIEAVAEGIRAMKNSASSLLSGEDASEASSYFDYVIGAMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW30</accession>
    <name>A0A2G4EW30_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000204">
        <property type="protein sequence ID" value="PHX53387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53387">
        <property type="protein sequence ID" value="PHX53387"/>
        <property type="gene ID" value="CP500_021750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009717">
        <property type="entry name" value="Mo-dep_Nase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06967">
        <property type="entry name" value="Mo-nitro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mo-nitro_C" evidence="1">
        <location>
            <begin position="43"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="14719" checksum="2D9743CACF0706F1" modified="2018-01-31" version="1">MNVFQHMLPDRILPIWVWVDKPKTVVTVATTSQYCGRKPRFDLLHPLKQWLDSVEIKSQKLARFLCKFIPSQCPFEREVKIRDRILFCIPPLCKLNPLYEQVVGIRFRALCYLADECGEDVTTYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW53</accession>
    <name>A0A2G4EW53_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53754">
        <property type="protein sequence ID" value="PHX53754"/>
        <property type="gene ID" value="CP500_019770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="9562" checksum="7D8CC24AF19AF91B" modified="2018-01-31" version="1">MLMQLFLQKRFLRSLSRECQLKFKRKVLRKLGVRSHRNRGDRHKGDRHSRHSQDNGFFFGLLFQGFVTFWFDRTNYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW63</accession>
    <name>A0A2G4EW63_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF839 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53775">
        <property type="protein sequence ID" value="PHX53775"/>
        <property type="gene ID" value="CP500_019695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008557">
        <property type="entry name" value="PhoX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05787">
        <property type="entry name" value="DUF839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="750" mass="81007" checksum="2E18F93A0D78DCCE" modified="2018-01-31" version="1">MSIKRREFLLFLGAGTVALNSCQQKAFMPFGNPVSATKISANLEGGINFKPIKGPMPLSGSSTVAQTGELIQISAASSQQQIQAYSTYEVADDLILPEDFTYDIIAAWGDKVGDSRFGYNNDYLSFVETSKNEGFLTVNFEYISAKPWIETYQKVIGKSLPFAQLATALKPAGKDGINAFALADKDPTKKMISEVLKEALIDLGMGVISIRRNPDGKWERTNSPADRRITGISGLTDGRYLKSTGPAVAIFNKKGQGYEDKLGDKIIGTFANCAGGTTPWGTVFSAEENTQNFVPEPVFADGTSFDPSQKNFYIDAEEIGGLGNLFGLAGNKYGWMVELDPANPNDYGTKHTWLGRYRHEAVGIRVVAGKPLAFYSGCDRRSGHLYKFVSKNTVKDPKNKANSQLLTDGMLYAAKFNPDGTGSWIPLKADTAVNPDLPSIHAGGIINLPKRPEGGIFKLDKDTDVVSFKQKFKTLGDLYEGTAKEKQGAILIDAHYAASAAGATCTARPEDTEIAPDGSLYITFTSGAASDSDGGPDLRIFQGKDGKAYEYGWIMRLIEDSNEPSAMTFNWKMFATGGEPADGGLGFANPDNLMIDKSGNIWMVNDMSSDKLNTAIPAGRVGKDGKPISQSSLRALYGNNAIWFLPASGPKAGEAFLFGIGPMDCETTGPFFTEDETTLFLAIQHPGEVNGTRQDMAFESRELAMKTTDGQEFMQTRKVPIGSNWPGNQANDPPKPAVVAIRRVNLGAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW94</accession>
    <name>A0A2G4EW94_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53710">
        <property type="protein sequence ID" value="PHX53710"/>
        <property type="gene ID" value="CP500_020125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="7823" checksum="B3D5C66C4C67BA3C" modified="2018-01-31" version="1">MMLVRDVIKQAIATGYLSLEAENEIQQIFSSAQCELEDLNAFMSLQLAAMAGRVKQQSLESINLPHHAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWD3</accession>
    <name>A0A2G4EWD3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000150">
        <property type="protein sequence ID" value="PHX53831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53831">
        <property type="protein sequence ID" value="PHX53831"/>
        <property type="gene ID" value="CP500_019335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013854985" evidence="1">
        <location>
            <begin position="31"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="169" mass="17907" checksum="6C96799A8194B662" modified="2018-01-31" version="1">MKRVRWLSGLFSAGMLCVMLGTVGAQVAQAQRPIFLLDLTCVNRGSGQYQKVSEDISVGRELYTAVLRVWPNAAFTCRLSGGSGTLRMEYGMSDTAIGNAPITITVYLDGNQVESKTASPGQVGTLLVNVSGGKSLAIETACARATNCEATLRLFKAQIEPGTRSPGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWH8</accession>
    <name>A0A2G4EWH8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000154">
        <property type="protein sequence ID" value="PHX53790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53790">
        <property type="protein sequence ID" value="PHX53790"/>
        <property type="gene ID" value="CP500_019565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008769">
        <property type="entry name" value="PhaF_PhaI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38664">
        <property type="entry name" value="PTHR38664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05597">
        <property type="entry name" value="Phasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="12742" checksum="2826A4FB26AB2ACC" modified="2018-01-31" version="1">MDNNNNLLKQLVMLGIGTTSLVAEKLQEVSEQWVKDGTINPEQAKTFVDDMTEQLKSEQGNWETQLQRQLRNMLQDMGVPRQSEMDELRGRLDRLERLVRDLENRNWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWL5</accession>
    <name>A0A2G4EWL5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="3">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_019245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000148">
        <property type="protein sequence ID" value="PHX53856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53856">
        <property type="protein sequence ID" value="PHX53856"/>
        <property type="gene ID" value="CP500_019245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="PTHR23407:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="10"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="133"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="192" mass="21745" checksum="3B00DE4242303C29" modified="2018-01-31" version="1">MNTPKPLLTKTELRKSLLQTRKSRSPEAWREKSDRICSHLQTSPPFTQAKTILAYFSFRQEPDLSPLFTIPKKWGFPRCVGKELSWHIWQPGDALQTGAYGILEPLPDAPKIDHSEVDLILVPAVGCDLRGYRLGYGGGYYDRMLSKAEWKSKVAIGIIFEFSLLAQLPVDSWDQPLHGICTESGNLKFNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWP1</accession>
    <name>A0A2G4EWP1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphate ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000135">
        <property type="protein sequence ID" value="PHX53972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53972">
        <property type="protein sequence ID" value="PHX53972"/>
        <property type="gene ID" value="CP500_018675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="2">
        <location>
            <begin position="103"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="377" mass="40629" checksum="0177F7257B7E866E" modified="2018-01-31" version="1">MSSGSNKVECPNCKTQNPSTAYKCSYCRKKLRGVPPIVLGLATVFLMLGGPYFLFKDKLFGAPSSTSTTSSSSPPTTPVTPSSAPFTTYLSLANIPNVPNGIFNYGGSTTFAPLRSPAVVAAINKAHPQFQLRYTKPPNGKPGSGTGIEMLIEGQMSFAESSRSVKDDEFELAKKRNFKLEQVAVAIDGIAFYVNPELIKQGFKGITLEQARDIFIGKVNNWKDVGGPDMEITPFSRNLKAGGTVDYFYEKVLDKQPLGSNVQEVTDTTGSIRKVGVTRGGIGYATASEVINQSMINLLPLGKVASSGFVSPCIDQICKAVNKTAFTDGTYPLTRRLFVVIKQDGKLDEQAGVAYTNMLLSDEGQKLVEEAGFVPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWQ4</accession>
    <name>A0A2G4EWQ4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">guaA</name>
        <name evidence="12" type="ORF">CP500_018535</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53975">
        <property type="protein sequence ID" value="PHX53975"/>
        <property type="gene ID" value="CP500_018535"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9 10" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="11">
        <location>
            <begin position="221"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="248"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="544" mass="61014" checksum="7DB1068C15237924" modified="2018-01-31" version="1">MSNYPLTVITQIETESALTNSSLGQIDRQMIVILDFGSQYSELIARRIRETQVYSEVISYRTTAQQLAAINPKGIILSGGPSSVYDEKAPQCDPEIWNLGIPVLGVCYGMQLMVKQLGGVVERAKLAEYGKASLSINDPTDLLTNVEDGSTMWMSHGDSCTELPEGFEILAHTENTPSAAIAHHEKNLYGVQFHPEVVHSIGGQALVRNFVYHICECEPTWTTATFVEESIREIRAQVGEKRVLLALSGGVDSSTLAFLLHKAIGDQVTCMFIDQGFMRKYEPERLVKLFKEQFHIDVEYVNARERFLAQIAGITDPEVKRKRIGHEFISVFEEESKRLGPFDYLAQGTLYPDVIESADTNVDPKSGERVAVKIKSHHNVGGLPKDLCFKLIEPLRKLFKDEVRKVGRSIGLPEEIVNRQPFPGPGLAIRILGEVTAERLNILRDADLVVRQEINRHGLYNELWQAFAVLLPIRSVGVMGDQRTYAYPIVLRFITSEDGMTADWARVPYDLLELISNRIVNEVKGVNRVVYDITSKPPGTIEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWU8</accession>
    <name>A0A2G4EWU8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage Gp37/Gp68 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000133">
        <property type="protein sequence ID" value="PHX53999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53999">
        <property type="protein sequence ID" value="PHX53999"/>
        <property type="gene ID" value="CP500_018510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011101">
        <property type="entry name" value="DUF5131"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07505">
        <property type="entry name" value="DUF5131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="262" mass="30564" checksum="B70DDA34EA221541" modified="2018-01-31" version="1">MSSINTGIEWCDRTWNPTTGCDKVSPGCTHCYAEALTKRFHTNFPNGFDLTEYPKRLNEPKTWRKPSRIFVNSMSDLFHEDVSIEFLKQVFEVMRETPHHIYQILTKRHERLLELAPELDWSDNIWMGVSVENQNYVNRIDCLRKVPAKVRFLSCEPLLGPLQLDLTDIHWVIVGGESGQKHRPMQEEWAQSIRDQCQDAGVAFFFKQWGGRTPKAAGRLLDDKIWDEMPEAWEKHQKKWNGYTLSVSRNSNKVVTPTLVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWX3</accession>
    <name>A0A2G4EWX3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Prevent-host-death family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000135">
        <property type="protein sequence ID" value="PHX53966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53966">
        <property type="protein sequence ID" value="PHX53966"/>
        <property type="gene ID" value="CP500_018640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="9974" checksum="A611F334BC0678B8" modified="2018-01-31" version="1">MTIKELLIQEIDSTPDELLADLLSLVRSLKSPPHPQVNTYEQLLERIDYLEAIIGIRKGLESFDRGEGIPVDRAMTALQQQFNIPQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWZ6</accession>
    <name>A0A2G4EWZ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000129">
        <property type="protein sequence ID" value="PHX54053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54053">
        <property type="protein sequence ID" value="PHX54053"/>
        <property type="gene ID" value="CP500_018215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014056">
        <property type="entry name" value="Addiction_killer_pred"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41791">
        <property type="entry name" value="PTHR41791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028744">
        <property type="entry name" value="Addict_mod_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02683">
        <property type="entry name" value="upstrm_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="13227" checksum="31FCD60EF490CB38" modified="2018-01-31" version="1">MEVQPREIRNYLRSDGTDPFEDWYNSLRDTTGKNKIRLRLKRVMTGNLGDCKSVGEGVFELKIDFGPGYRLYFGQVGLTIVILLIGGDKSTQERDIGKAIQYWRDYEQRESTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX18</accession>
    <name>A0A2G4EX18_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53990">
        <property type="protein sequence ID" value="PHX53990"/>
        <property type="gene ID" value="CP500_018525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="33"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="152" mass="18065" checksum="EC14235CD492172B" modified="2018-01-31" version="1" fragment="single">MYQTEQSPTPKNVLPTMYDLPSEHPEDSGLPDLYHLWQSRCLEYTFRPSNYPIELVFVASDLNLYFDVRHTQWYKRPDWFGVVGVDRLYQKQELRKSYVIWQEEVSPFVVVELLSPGTENEDLGQTVRGLGQPPTKWQVYEQILRVPYYIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXS5</accession>
    <name>A0A2G4EXS5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_017050</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54278">
        <property type="protein sequence ID" value="PHX54278"/>
        <property type="gene ID" value="CP500_017050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045276">
        <property type="entry name" value="YbiO_bact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30460">
        <property type="entry name" value="PTHR30460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="526" mass="58896" checksum="4551ACDE69E72255" modified="2018-01-31" version="1">MTNLLIVLAEVGLVIIIFLFLTWLVGNLSKLSIKLSIFKLDDRGIKILRRQSTGLLLLACSVLCILIVGANGFLLYRGEDLEKYTLDLILRIPSEFWLTLGIGIAQSIGIVIVAAIALKVLKYCLKVASTRVKNIDKSTADDESIDAFFRSLYQRIKWGIWLWAIVSCTQFLKLPGVVSDYLSIALRIYLIVAVGLLILKAVAAIVDTLDALSIRYSSPDNLLRFYDRLQHLIPLLKRCLEFAIYVCMATLVTQQIELIAKLSDLGLRIIKIIAIIFISQVFFEVIYLLIEEVAFKDHNLTEIQTSRRLTLIPLFRSLLQYLVYFTVGISILYTLDINPAPILAGAGIVGIAVGLGAQTLINDIVSGFFILFENYYLVGDYIEAGKAEEKTVEGTVEAIELRTTRIRHPNGQLQIIRNGDIGSITNYSKQYIFAVVEFCVPYNANLAKVYQVIEEIGQELKANYSDVLEPTQVDGVASLSESNLLLRTMTKVKPGKHILIQRILRKKIMDTLLQESILFPAQIESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXU8</accession>
    <name>A0A2G4EXU8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53987">
        <property type="protein sequence ID" value="PHX53987"/>
        <property type="gene ID" value="CP500_018615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7405" checksum="DF1D41D3A9C43FE8" modified="2018-01-31" version="1">MGFGLIPPINLGACTIKKLLIIRFEILDFGFSIDPTDKFGGLKILDFGFWIDSTDKSGGLYHQEIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXV6</accession>
    <name>A0A2G4EXV6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metal ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016715</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54316">
        <property type="protein sequence ID" value="PHX54316"/>
        <property type="gene ID" value="CP500_016715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013558967" evidence="4">
        <location>
            <begin position="30"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="325" mass="35788" checksum="5DD12589685EA936" modified="2018-01-31" version="1">MNHQAFCRKTYKIGIFGLLLGFWLSGCNAQTTEPQTKQNGDSSSTASKLTRKDKKVILTTFTVLADMAQNVAADKAIVQSITKPGAEIHGYEVTPSDLKRGQNADRILENGLNLERWATRFYNSLPKVSHITLSEGVQPVNIAEDAYQGKPNPHAWMSPKNAVIYVENIRKTLGNLDPVNAASYNANAAKYSEQIRAIDAKLKQAISAIPPDKRYIVSCEGAFSYIARDYGLKEVYLWPVNAEQQATPKQVERVINTVKANKIPAVFCESTVNNEAQLQVAKETGAKFAGVFYVDSLSPPDGPASTYLKLLEYNVNTLIKGLQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY64</accession>
    <name>A0A2G4EY64_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exostosin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54473">
        <property type="protein sequence ID" value="PHX54473"/>
        <property type="gene ID" value="CP500_015930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exostosin" evidence="1">
        <location>
            <begin position="244"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="369" mass="42225" checksum="80DE1E1097B25C22" modified="2018-01-31" version="1">MAYCKLNCKAVLKGRGFRPIFLMTRLIRLTTLGIELAHKSNFPDGCPILKAWHGNYFPAFNQTIQENFQIVENQDADAFLLPSNVSFYTPNRLKEIGEIVTDLKIPSIGFDISKESRKPKWLDYIIRFSWYRQIQESGGIISPAYLNSDGFDLVTETNIRNWEPTPKEIIPSVSFCGREGGAVGLAVWKILPRSLTRWMATDFFCSTTKGIRMTCCYPLRIDAMEIIKKDPRIKTDFVGRGSAGMQPGVQGNQRQEFVDNLLRNAYALCVRGTDNYSWRFYEALSLGKIPVLIDTGCLLPMEDEIAWDNFILRVPVAQLPELPDRLLAWHSSFSPQAFGELQRDLRAIFQRIRPANFHLEMFRKILPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYB8</accession>
    <name>A0A2G4EYB8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000094">
        <property type="protein sequence ID" value="PHX54523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54523">
        <property type="protein sequence ID" value="PHX54523"/>
        <property type="gene ID" value="CP500_015620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="84" mass="9608" checksum="459803FEE6629BE9" modified="2018-01-31" version="1">MVGLDLEIISNVHWKCQGNEQKNMANNNPSPNTRFVGTGKGIKNNQKGFNVRFPEPYHSMLAEIPDRIEFIRQAVIEKLKDKPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYG1</accession>
    <name>A0A2G4EYG1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000115">
        <property type="protein sequence ID" value="PHX54207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54207">
        <property type="protein sequence ID" value="PHX54207"/>
        <property type="gene ID" value="CP500_017390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="6697" checksum="2A0002F7111EFA69" modified="2018-01-31" version="1">MTQPNLRLQTCNRQDACSTIDEFSCNRQDACFTIDEFSCGTGILPVPKQVIENGATSQYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYW8</accession>
    <name>A0A2G4EYW8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54690">
        <property type="protein sequence ID" value="PHX54690"/>
        <property type="gene ID" value="CP500_014835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="31994" checksum="4218B2D70BD7DE49" modified="2018-01-31" version="1">MNPHLLLNRVAVLATMHQKEQVMAPILERELGVKILVPADLDTDSFGTFTREVKRLGTQIEAVRLKATKALEIAGETLAFASEGTFGPHPGMPYLPANREIVILLDIANNLELIGEYFSVETNYSHQLVSCTEEAQVFAKKVGFPEHALVIVVGDSTKDYAEIVKGIVTEKQLFDVVNAALKKSSRGQVHVETDMRAMYNPTRMKNIENATLDLVKKFYHFCPECGWPGFKVAERKIGLPCGLCHFPTQLVRSQIYQCQNCSYTKEELFPNGRETADPSQCQYCNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYX3</accession>
    <name>A0A2G4EYX3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF29 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000082">
        <property type="protein sequence ID" value="PHX54711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54711">
        <property type="protein sequence ID" value="PHX54711"/>
        <property type="gene ID" value="CP500_014605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002636">
        <property type="entry name" value="DUF29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34235">
        <property type="entry name" value="PTHR34235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01724">
        <property type="entry name" value="DUF29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="145" mass="16612" checksum="71487621EC9FD9D2" modified="2018-01-31" version="1">MEELMELKELLHRGKVAEALVLVAELEEMSKSDKLNKIFSYGIILLLHLIKKVAENRTTKSWETSIFNSVKQIQRTNKRHKAKGTYLTEEELVETLEDAYESGLKSAALEAFEGIYDVEEIAKMVNRDDIMKMAIGLILDKQPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYY8</accession>
    <name>A0A2G4EYY8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cinnamycin family lantibiotic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54729">
        <property type="protein sequence ID" value="PHX54729"/>
        <property type="gene ID" value="CP500_014565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046016">
        <property type="entry name" value="DUF5973"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19398">
        <property type="entry name" value="DUF5973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="96" mass="10498" checksum="D55BB512AF5B378E" modified="2018-01-31" version="1">MKKNNVAETLVANPVEELLLRAVIDPEFRSEILTNPEAFGIPTNTETLVFLHSVAQQDMSFVELVNDSTNFAAPGSDNCRCTCVTGFTLRCDGTSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ20</accession>
    <name>A0A2G4EZ20_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">S-methyl-5'-thioadenosine phosphorylase</fullName>
            <ecNumber evidence="3">2.4.2.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-methylthioadenosine phosphorylase</fullName>
            <shortName evidence="3">MTA phosphorylase</shortName>
            <shortName evidence="3">MTAP</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mtnP</name>
        <name evidence="5" type="ORF">CP500_014630</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (phosphorylase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homohexamer. Dimer of a homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.28" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000082">
        <property type="protein sequence ID" value="PHX54718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54718">
        <property type="protein sequence ID" value="PHX54718"/>
        <property type="gene ID" value="CP500_014630"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00873"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09010">
        <property type="entry name" value="MTAP_SsMTAPII_like_MTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01963">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010044">
        <property type="entry name" value="MTAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018099">
        <property type="entry name" value="Purine_phosphorylase-2_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679">
        <property type="entry name" value="PTHR42679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01694">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01240">
        <property type="entry name" value="PNP_MTAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="4">
        <location>
            <begin position="5"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="3">
        <location>
            <begin position="54"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="3">
        <location>
            <begin position="87"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="212"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="290" mass="31599" checksum="79E3D8ABEA647A30" modified="2018-01-31" version="1">MAQAKIGIIGGSGLYKMDALKDVQEVKIDTPFGEPSDAAIVGTLDGTTVAFLARHGRNHTFLPSEVPYRANIYAMKSLGVEYLISASAVGSLKIEAKPLDMVVPDQFIDRTKNRISTFFGEGIVGHITFGDPICGELAKVLASAIADLNLPDVTLHRGGTYVCMEGPAFSTKAESHLYRSWDATVIGMTNLPEAKLAREAEIAYATLALVTDYDCWHTDHESVTVEMVIANLHRNAENAQKVIQETVRRLTENPPVSESHSALKYAILTPLDKVPVATKEKMGLLLQKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ59</accession>
    <name>A0A2G4EZ59_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54804">
        <property type="protein sequence ID" value="PHX54804"/>
        <property type="gene ID" value="CP500_014145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="3"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="15505" checksum="6EFD4763BA0CABF6" modified="2018-01-31" version="1">MALSVGTDAPQFTAKDTNGNTVSLSQFAGKTVILYFYPKDDTPGCTRQAQSFKAAHEEYIAKDIVVLGVSRDNEESHQKFTEKYGLPFQLLADVDGAITTAYDVDGGGYAKRVTYVIDGNGKIIHVDGSVNTASHAQDILVTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZC4</accession>
    <name>A0A2G4EZC4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Cysteine synthase</fullName>
            <ecNumber evidence="4 10">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cysK</name>
        <name evidence="12" type="ORF">CP500_013865</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4 10"/>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54863">
        <property type="protein sequence ID" value="PHX54863"/>
        <property type="gene ID" value="CP500_013865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="11">
        <location>
            <begin position="8"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="8">
        <location>
            <begin position="181"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX54863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="325" mass="34366" checksum="5B25AF93D704A35D" modified="2018-01-31" version="1">MKIAKDVTEIIGRTPLVQLNKIPQSEGVVAQIVVKLEGMNPAASVKDRIGASMIQAAEEAGLIEPGKTILVEPTSGNTGIALAMVAAAKGYKLILTMPDTMSLERRSMLKAYGAHLELTPGHEGMLSAIARAEEIVEATPDAFLLQQFRNPANPKIHRETTAEEIWADTDGKIDFLVAGVGTGGTITGVAEVIKQRKPSFRAIAVEPANSPVLSGGKSGAHKIQGIGAGFIPEVLKPELIDEVIAVSDEDAIGYSRRLAREEGLLSGISAGAALFAAIQVGKRPENAGKLIVFVQPSFGERYLSTALFKDLELPTVSQLEALISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZI8</accession>
    <name>A0A2G4EZI8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aliphatic sulfonate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssuB</name>
        <name evidence="5" type="ORF">CP500_013465</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54922">
        <property type="protein sequence ID" value="PHX54922"/>
        <property type="gene ID" value="CP500_013465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="10"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="272" mass="30082" checksum="DD230B50DFA499B5" modified="2018-01-31" version="1">MESALSGMRLELVELQKSFGNIEILRDINIEINPGEFVAIVGRSGCGKSTLLRLIAGLEVPSQGAVFLDEKSSHKLNSKVTMMFQDARLLPWQKVLANVQLGLLAAKENTHYKAMQVLHAVGLADRANEWPAVLSGGQKQRVSLARALACEPHLLLLDEPLGALDALTRIEMQQLLENLWQEKGFTALLITHDVEEAVVLADRVILIENGQIAMDCSIDLPRPRQRGNAVFAAKVEAILQRVMGEKESSKDAEKFAIGRYKKPNYVKMSKYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZK6</accession>
    <name>A0A2G4EZK6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54627">
        <property type="protein sequence ID" value="PHX54627"/>
        <property type="gene ID" value="CP500_014980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="8"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="188" mass="21721" checksum="AE4B091A2B555CF9" modified="2018-01-31" version="1">MASNPIALYDACVLYSAPLRDLLMQLALTDLFQARWTDEIHDEWIRNVLKNRPDLTIEQLTRTKDLMNRYVRDCLVTGYEWIIPSLNLPDPNDRHILAAAIKSEASAIVTFNLKDFPPLILDQYEIEAQHPDDFILDLIDLNYLKVANAVTTCHQRLKNPPKSLDEYLEILLKQGLQSTVKSLQQIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZN8</accession>
    <name>A0A2G4EZN8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54972">
        <property type="protein sequence ID" value="PHX54972"/>
        <property type="gene ID" value="CP500_013195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="94" mass="10042" checksum="05CAB215BB3B9C78" modified="2018-01-31" version="1">MISAISRVFAAPRPSSSNKSKPMPPVRISLPFPPSRISFPAPPLSVSKPLPPSSLSLPLLPVRISLPLLPFKAILLPRIPVKLSSLSVPLISFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZU4</accession>
    <name>A0A2G4EZU4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_014585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000082">
        <property type="protein sequence ID" value="PHX54717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54717">
        <property type="protein sequence ID" value="PHX54717"/>
        <property type="gene ID" value="CP500_014585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="171"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="205"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="273"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="307"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="341"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="399" mass="45626" checksum="55FB06F044EECAAF" modified="2018-01-31" version="1">MLFLGHWKNLELLNREDAKDTKEEKVRSKSSFTGKGVTVLVQQQSEQQELKEEIRDRVQEEVDIAFGRTAVLLNGIVIALTLFPTAAGVAVWFLLAKLSNQTTIARQEIESLRYDTLSQLKFLISDAETILVEIQHQSHPADAETDILLPDAQIQEFAPVNDDNYKQLLTAGDYAKQGDACFFENRYEDAIAAYNQALQIQPDLADTWNNRGVVLTRMQRYPEAIASYEQATTIRPNYPDAWNNRGVVLLELQHFPDAIACYDQAIQAKPNYADAWNNRGVAFSKMQEYEQAVISYNQALQIKNDYTDAWNNRGVALSKLQKYEAAIDSYENAAKIRPDFYRIWYNKARCYALQGQTDLAIENLKRALNLNPSLCKELAKTEPDFEKIREYEAFKQLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZV2</accession>
    <name>A0A2G4EZV2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55038">
        <property type="protein sequence ID" value="PHX55038"/>
        <property type="gene ID" value="CP500_012785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011719">
        <property type="entry name" value="CHP02058"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34784">
        <property type="entry name" value="PTHR34784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09585">
        <property type="entry name" value="Lin0512_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02058">
        <property type="entry name" value="lin0512_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13003" checksum="97901572A8E601D4" modified="2018-01-31" version="1">MARKCFIIEMGMGIDQHGQEPTVAAARAVRNAIANNALLGVWEVAGLTDPNQMIVEVKVAVPYPEQVRGDEVLAVLPFGEKTLIVEQGGMVVAGRAIASLNDKNDEMLIAVAAVTVFVDTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F002</accession>
    <name>A0A2G4F002_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Exopolyphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55092">
        <property type="protein sequence ID" value="PHX55092"/>
        <property type="gene ID" value="CP500_012520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016877">
        <property type="entry name" value="UCP028235"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028235">
        <property type="entry name" value="UCP028235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="311" mass="35805" checksum="897833545E125345" modified="2018-01-31" version="1">MSYTKKYRLVTRSDFDGLVCAVLLKELDIIDEIKFVHPKDMQDGKIAITNNDITTNLPYVEGAHLVFDHHFSETLRHEKIQKNHIIDPYAASAARVLYKYYGGQPKFPQISEAMMEAVDKSDSAQFSQEEVLHPEEWVLLNFIMDARTGLGRFKKFTVSNYQLMMQLIDYCQNHKIAEILELPDVKERVELYFDQEEKFKDQVQRCAKVYNDLVVLDLRNEQIIYAGNRFIIYALFPECSISIHALWGLKQQNTVFAVGKSIFNKKSQVNIGHLMLRYGGGGHMNAGTCQIENDKASKILNELIAEIDRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F069</accession>
    <name>A0A2G4F069_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012270</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55151">
        <property type="protein sequence ID" value="PHX55151"/>
        <property type="gene ID" value="CP500_012270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="3">
        <location>
            <begin position="462"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="398"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="683"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="767" mass="85858" checksum="E5E96631AA1C2D45" modified="2018-01-31" version="1">MTQHNLGTAYSNRIEGVRAANIELAIACYREALKVRTRENYPEDWAMTQNNLGAAYSDRIEGVRAKNIEEAISYFRLALEIYTPTAFPFNCLTTGRNLGNTAFTAGFWDIALEGFEKAIQAVEKSRSWATSDDIRQQMIAESIGVYEKAIQAAVNNNQLEKAIEYCDRTRAQRLVDLMHSNDLYASGEIPPEVQKYLDEFEAKQQEIDAEVEQLRNPSEGDKGLAGVGSSSRSRADTSAYTKKIQELEGEKQQIWENIRSLDPVLAGQVQVVPMEFAAMQQLIDNSQTAILCFFTTQNDTHVFVIYKDKAPQIHTCQGEGWASFQKWIDKGWLSPYLEDRKGWWQGMGEFLSQLSRRLKVDELIGNCLAGIEELIVIPHLYLHQIPLAALPVNTLATEEGGHGGTAPTNPGLESGNSSLGVEEEPPQPPLAKGGLKSEISALTKEQESLLSPPLSKGGPGGVLSDYFLIRYIPSCRILEYCSQRPTIESPKYGIVENATDDLYFTPFECEQIAEIVTVTERLKGSQQAKVTAYRNLAQNVNVIHSSHHAVSRLDNPLESRLFLGDGSITLGELMTPGWRLPQLSDVFMSCCETNLGDTEITDNLLSLGTGFLCAGARSVVSTLWAVDDFATSLFSIFYYQYRLEGLSRPEALRRAQVRLRTISGAELKGLYQPQIDALLPRIIGDLKRKLNLVQEELEDLESQQKKYKGGTAEYKELEEKLNKKTEEEVEIGKRKEGYESLQKNLYTMSNPFDDLIYWSGFICQGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F086</accession>
    <name>A0A2G4F086_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_013830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54857">
        <property type="protein sequence ID" value="PHX54857"/>
        <property type="gene ID" value="CP500_013830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015419">
        <property type="term" value="F:ABC-type sulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102025">
        <property type="term" value="F:ABC-type thiosulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03296">
        <property type="entry name" value="ABC_CysA_sulfate_importer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005666">
        <property type="entry name" value="Sulph_transpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005116">
        <property type="entry name" value="Transp-assoc_OB_typ1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03459">
        <property type="entry name" value="TOBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00968">
        <property type="entry name" value="3a0106s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0764">Sulfate transport</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="3"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="343" mass="38080" checksum="54C4792C43BDCB0B" modified="2018-01-31" version="1">MSITIQNVSKHFGSFHAIDNVNLEIKSGSLVALLGPSGSGKSTLLRMIAGLEPPDSGHIYLIGEDATRQSVQERHIGFVFQHYALFKHMTIKKNIAFAMEIRKVPKDSIRRRVDELLDLVQLTGLGDRYPSQLSGGQRQRVALARALAVQPKVLLLDEPFGALDAKVRKELRSWLHNLHKEVNITTVFVTHDQEEAMEVADEIVVMNKGRVEQVGTPAEIYDKPATAFVMSFIGPVNVLPNAAGLFASNVTTAQNSGAAHSEVVFLRPHDVEIQTKPESGFALAKVSRIIHLGREIQTELLLESGQMVTAYLSRDRFDALQLQREQQVYVKPKHAMTFPAYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0I2</accession>
    <name>A0A2G4F0I2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55263">
        <property type="protein sequence ID" value="PHX55263"/>
        <property type="gene ID" value="CP500_011715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="168" mass="18502" checksum="08F068E8EDF9986E" modified="2018-01-31" version="1">MIGDFGVGKTSLIRRFVDRQFSDQYLSTVGVKISRKSIVLENSTKQEIVTAQLLIWDLEGHTKFKGIAPTYLQGAGGVLIVADVSRSETVERISEHIQLFASVNPKGSIIIALNKVDLIDEEKLALLVEVAHSIGQDQVVAVYTTSAKTGKDVDEIFHKLAYTMVEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0I8</accession>
    <name>A0A2G4F0I8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="5">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="5">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="5">IPP transferase</shortName>
            <shortName evidence="5">IPPT</shortName>
            <shortName evidence="5">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">miaA</name>
        <name evidence="9" type="ORF">CP500_011525</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5 7">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55270">
        <property type="protein sequence ID" value="PHX55270"/>
        <property type="gene ID" value="CP500_011525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="34"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="303" mass="34449" checksum="49E81F77005C74E0" modified="2018-01-31" version="1">MSKLITICGATATGKSGVAVAVAQRLRSPILSADSRQVYREFDIGTAKPTKVDRTSVPHHLIDICDPRETLTLAEYQQQAQNLIAAVDSPVLLVGGTGLYIKSIVRGLKIPRVAPIPELRSQLVELGQAQCYQMLQQVDRSAAEKIHLNDPVRTLRALEVFYVTGRSISEQQGENPPSYPILQIGLDCDLEVLVDRIKQRTEQMLESGWLAEVEYLCQKYGCDLPLLNTLGYQEMKQYLAGDIKLEEAKKLTVLHTRQFAKRQRTWFRAYPEIEWFDVSKPDLCDRVWRRVEEFVKEDFGDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0J9</accession>
    <name>A0A2G4F0J9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_011665</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55294">
        <property type="protein sequence ID" value="PHX55294"/>
        <property type="gene ID" value="CP500_011665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10147">
        <property type="entry name" value="Wzt_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029439">
        <property type="entry name" value="Wzt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14524">
        <property type="entry name" value="Wzt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="23"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="59"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="470" mass="51820" checksum="37A60E3727ED10E5" modified="2018-01-31" version="1">MTETVISLKNVSKCFKRYDRPGDRLKEMIYPSKKLADEFWALQDINLEISQGQTLGIVGRNGSGKSTLLQIIVGTLTPTAGTVEVKGRVSALLELGSGFNPEFTGRQNVFFNAQILGFNQKETAEKFDEIAAFADIGDFIEQPVKTYSSGMFVRLAFAVATSVEPDILVVDEALSVGDEAFQRKCFARLQSIQEGGGTILFVSHAATSVVQLCTSAILMDSGELLLAHTPKVVISKYQKLIYADPDKVLELKEDIRGLNKLTKQESETDLQDTQSENKHTEIPPEQSLPKLKEYYEEFYDPGMIPSNTVRYPSRGAEIINPRITTLKGNVVNHLIGRQDYIYTYSVTFSNSTSKVRFGMLIKTISGFELAGASLKASTQSVKYVEAGTTVVVKFQFKCLLNPGVYFLNAGVVGTVDEDLTYLDRCVDIAMFRVQSCTESCGNGIVDLLIEPCLTVVNSDYLLKEASSEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0N4</accession>
    <name>A0A2G4F0N4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">APAF1_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_011490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55320">
        <property type="protein sequence ID" value="PHX55320"/>
        <property type="gene ID" value="CP500_011490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041452">
        <property type="entry name" value="APAF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17908">
        <property type="entry name" value="APAF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="APAF1_C" evidence="4">
        <location>
            <begin position="14"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="187"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="271"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="351"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="368"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="410"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="452"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="494"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="536"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="578"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="620"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="662"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="704"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="785" mass="85073" checksum="2117BB04033B9561" modified="2018-01-31" version="1">MSKFKERLGKLSPKKRLYALETLPGHLAESVQGERLHQLLTDFDFIEAKLDAVGVQALIEDYDLARVSDVLLSEGQTETLRLIQGAIRKSAHVFEKDKTQLAGHLLGRLLPSEITMIIDESKYFWEYLPLIARFSPRKPVKKVTEKISSPDDIQSMLEQAKQSKNTPWLRPLRANLERANEGALRTLAGHTDGVKAVAIAPDGKRVISASGDKTLKIWDIDSGTELRILTGHTDEVWGVAIAPDGKRAISASGDKTLKIWDIDNGTELRTLTGHTDGVYAVAIAPDGKRAISASGDKTLKIWDIDSDRELRTLTGHAGVVKAVAIASDGKRAISASRDQKIWYGDKIWYGDKTLKIWDIDSGRELRTLIGHFGSALSVAIAPDGKRAISASGDKTLKIWDIDSGRELRTLTGHTGVVLAVAIAPDGKRAISASRDRTLKIWDIDSGRELRTLTGHTYAVTAVAIAPDGKTTISASNDSNLKIWDIDSDRELRTIAGNIREVLSVAIAPDGKTVISASRDYTLKIWDTDTGRELKALIGHTNLVKAVAIAPDGKRAISGSWDKTLKIWDIDNGKELRTMTGHTKPINAVTIAPDGKTAISASRDYTLKIWDIDNGRKLRTMAGHTESVNAVAIAPDGKTAISASDDKTLKIWDINSGRELRTMTGHTSEVWGVAITPDSNTAISASNDRTLKIWDINSGRELRILTGHTDSVWGVAISSDGKLAISASDDKTVKIWDLPSGKEVASFNGDYAFAGCAIAPDGVTVVAGDRSGRVHFLRLEGVSGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0T9</accession>
    <name>A0A2G4F0T9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SulP family inorganic anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_010915</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55379">
        <property type="protein sequence ID" value="PHX55379"/>
        <property type="gene ID" value="CP500_010915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="436"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="554" mass="59182" checksum="349DD9FBF624D10D" modified="2018-01-31" version="1">MTVANSFMGLRFWFDRTFGHWRGDLTGGLTAAVVALPLALAFAVASGVEPKAGLYTAIVAGIVAAVFGGSPVQITGPTGAMAVVLIGIVTKYGIEKVWIAGVMAGIIQVALGVAKLGRLVKFIPYPVTAGFTNGIAVIIFCGQLNNFFGLQLPRSEHFLPGIWQTFTHWEGLNWEAVGLATVVILTKLFWTRITTAIPGSLVGLVLATAIASFFHLDVPTIGSIPQSLPMPQGIPHGNDFRLIRELINPALALAALGSIESLLSAVVADGMTVSEKHNSDRELIGQGLANIIVPFFGGIPATGAIARTAVNVRSGGKTRLSGVIHGVALAIIVLTLAPLAAQVPLAALAGILMVTSVRMIEWEAIGLLMRATYSDFGVMMLTWMVTILFDLVLAVEVGLIAAGALFIKRMSELNLTKIPETEAFPPGVPLELSKQIAVYRVDGPVFFGAAERFVTFLRDEPEVKYLILRMRFVPNMDTTGIVALEDIYRDLKRHDCRLLLTGLQPEVQNLLERTGLLDKIGKENCFETTDAAVCALTPTAISCPLSPPLVTHSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F154</accession>
    <name>A0A2G4F154_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Photosystem I reaction center subunit XI</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">PSI subunit V</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">PSI-L</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_010600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PsaL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55468">
        <property type="protein sequence ID" value="PHX55468"/>
        <property type="gene ID" value="CP500_010600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
        <property type="term" value="C:photosystem I reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003757">
        <property type="entry name" value="PSI_PsaL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036592">
        <property type="entry name" value="PSI_PsaL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022980">
        <property type="entry name" value="PSI_suXI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34803">
        <property type="entry name" value="PTHR34803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02605">
        <property type="entry name" value="PsaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81568">
        <property type="entry name" value="SSF81568"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="PsaL" evidence="12">
        <location>
            <begin position="10"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="167" mass="17659" checksum="6910AE95121BBB3B" modified="2018-01-31" version="1">MADPRNAELIQPFNGDPFTGHLATPISASDFTKAFIGNLPAYRKGLSPLVRGLEIGLAHGYFLVGPEVVFGPLRDYPEAANLGGLITALALVLIGTLGMSAYGLVSFQENKTYASANPMTPEALKTGEGWSQLTAGFFVGGMGGVFAAYFLLENLKVVDAMFRGLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1H1</accession>
    <name>A0A2G4F1H1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-dependent DNA helicase RecQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_010010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55602">
        <property type="protein sequence ID" value="PHX55602"/>
        <property type="gene ID" value="CP500_010010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="34"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="235"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="482" mass="54736" checksum="C1825C27348E6FEC" modified="2018-01-31" version="1">MNFKPELTSLNQARATFQQIWGYDDFRPPQGEIVSSLLAGKDTLIIMPTGGGKSICFQLPALLQTGLTLVVSPLVALMENQVQELRDRNLPASLLHSQLSRQQRRQTMQSLEQNKLRLLYLSPETLLSKPVWEIISQPHIQINGLILDEAHCLVQWGDTFRPAYRRLGTVRSALLKTQPEGSKIAIAAFTATANPEAQKIIKNVLQLQKPEAFLLSPYRSNLHLQVQTVWTPRGRKQQLLNFIKSRPKQAGLVYVRTRKDSEKLANLLEESGYQTAAYHAGLSPEERRQIETAWLNNQLKFVVCTSAFGMGINKSDVRWVVHYQAPLLLSEYIQEIGRGGRDGKSAIALTLISEPTGWLYPEDKQRKEFFQDKLRSQYREAQQLAKNLPVKGTVDAVGREFPESAIALSILHSSGQLKWQDPFNYVINKSAQPKAEKPNFTIAEEMVKYLKYNQCRWQFLLEAFGFANEAKSMRCGHCDNCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1J3</accession>
    <name>A0A2G4F1J3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55626">
        <property type="protein sequence ID" value="PHX55626"/>
        <property type="gene ID" value="CP500_009860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="244" mass="25239" checksum="664ACC7E579567A9" modified="2018-01-31" version="1">MVEENPYLVALYHHLLAFLGAVPTLNQVILLIPIAVILAIVTALGSVICSGIALTPNQVIILIPITVILAIVEILGSVVCLGIALTPNQVIVLIAAVVTLTQVTVPTLAPAIVPTLAQAIVPVLEVVIMKIVAALGICSAVALTPNQVIVMIAATVILTQAIVPILTQAIVPTQAQAIVPTQTQATVPTQTQVMVPILTQATVPILEIVILEVEIMAIVADLIVTLAVVIVGGNTCFLWEGSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1P6</accession>
    <name>A0A2G4F1P6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55669">
        <property type="protein sequence ID" value="PHX55669"/>
        <property type="gene ID" value="CP500_009680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14873" checksum="3B366CE0BAC2B7A4" modified="2018-01-31" version="1">MKPKITSPIAWQQAELLMQPALIRVLDNIRKQLEESVWTGTYQEVHTPFPGYQLILDRQGEQRSIDIWELCYRVCFVNYQPAHSDMQSQEVVIDTLLIEEDTGDVDWMRLDAKTRQLIQEVFANLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Q2</accession>
    <name>A0A2G4F1Q2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55678">
        <property type="protein sequence ID" value="PHX55678"/>
        <property type="gene ID" value="CP500_009745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="289" mass="31665" checksum="60C8E9FB369AAE14" modified="2018-01-31" version="1">MWNSLTNLRLLSPSIPALVKVLVFFLTWTCLWLPIAIMMSIALKWQPPQPLGNKKLPLVASLYLIVPFILWATTWIENVSLADWGLFWQPATLISGLRGLGLGIVSLAILFGLQLALGWIELQNTEVETKTTEQIINPWASILNPSTLVILLLALWISATEELIFRGCLPNLLQQDYSIITAAAIANFIFAIAHLIWAPKETLPQLPGLWLMGMVLTLARVADGGSLGIAIGLHAAWIWGITIVDTAKLIKPSEKVPEWITGIAEKPLAGAAGILLLVTTGTLLFLMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1T6</accession>
    <name>A0A2G4F1T6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55733">
        <property type="protein sequence ID" value="PHX55733"/>
        <property type="gene ID" value="CP500_009235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="23"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="280" mass="32743" checksum="0F18D95B49D3C902" modified="2018-01-31" version="1">MLPFKYPVPQTEPPSSPRETLPTMYDLPSENAEEPGLPDEFHGLQPQLLSYTFRPSNYSAAQIFSGADMNLYYDARHPLWYKRPDWFGVVGVSRLYDEVDMRLSYVVWQEGINPFVVVELLSPGTEKEDLRENDLELPSTSQYLAGNGHINPEPRGGKPARKWEVYEQILRVPYYVVFSRYTNIMRAFKLEGARYQELQLSDSRVWMPEIDLGLGLWQGEYLGVDRLWLRWYDVEGNWIPTPEERAQQEQQRAELAEARLEFLMQRLRESGIDPDRFLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F204</accession>
    <name>A0A2G4F204_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenical resistance protein ArsH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">arsH</name>
        <name evidence="2" type="ORF">CP500_008870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55791">
        <property type="protein sequence ID" value="PHX55791"/>
        <property type="gene ID" value="CP500_008870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014063">
        <property type="entry name" value="Arsenate-R_ArsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43590">
        <property type="entry name" value="PTHR43590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02690">
        <property type="entry name" value="resist_ArsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="9"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="222" mass="25366" checksum="F7F0CDD8CA344B38" modified="2018-01-31" version="1">MKSFTHKPRILFLYGSLRERSYSRLLAEESARIIQDLGAEVRFFNPLELPIYGSVPDTHPKVQELRELSLWSEGQVWSSPEMHGNITGIMKNQIDWIPLTIGAVRPTQGRTLAVMQVSGGSQSFNAVNTLRILGRWMRMFTIPNQSSVAKAYQEFNDDGTMKDSPYRDRVIDVMEELYKFTILLRDQVDYLTDRHSERKEKAAKETIAVANSALEVNSPKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F293</accession>
    <name>A0A2G4F293_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55862">
        <property type="protein sequence ID" value="PHX55862"/>
        <property type="gene ID" value="CP500_008495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="273" mass="29111" checksum="C299AE634D547F44" modified="2018-01-31" version="1">MALHQHSFFLSEPLTLAEVLQTLEQSKSLAQTNLQGINLSQMDLSGIDLSGTNLIGANLSKTNFQGANLQGVDLRRASLRDANLSGANLQESYFFRADLQGCNLLNANLELAKFKLALYDSKTLWPEGFNYQKSEAIGPKASLSGAFLNTANLRGADLSYCNLRGAYLSGADLTGANLEGAALSGATLQNALLTGAYLRNAILIGAELQGADLRAADLTGANLEQLKSIAGADFSLVQGLTEEARAMLRSRSSKELGTWNSFTRNNTAQSLVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2A5</accession>
    <name>A0A2G4F2A5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gas vesicle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55890">
        <property type="protein sequence ID" value="PHX55890"/>
        <property type="gene ID" value="CP500_008320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024623">
        <property type="entry name" value="YtxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12732">
        <property type="entry name" value="YtxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12194" checksum="13CA2C04E2183B10" modified="2018-01-31" version="1">MSTKRSGLFIGGLLVGSAIGAVTGLLMAPRTGKETRQILKKSADALPELAEDLSTSVQLQADRLSESAMRNWDETLIRLKDAIAAGLEATQRERQTLSETEAELTSPSRPPSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2J4</accession>
    <name>A0A2G4F2J4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hybrid sensor histidine kinase/response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_007860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55994">
        <property type="protein sequence ID" value="PHX55994"/>
        <property type="gene ID" value="CP500_007860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="134"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="210"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="280"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="500" mass="56113" checksum="4C6385E9D468CAA8" modified="2018-01-31" version="1">MWIKILLVEDNPADADLLAELLEVSVGVEWELVSVEFLHSAIAHLSKQPFDIVLLDLSLPDSHGLETLTRLRKVAPDTAMVVMTGMDDEALGLKSVRLGAQDYIVKGQITTQLLVRTIRYAIERSQTFQMLRESERRFRAIFNSSFQLTKLLTPDGIVLEVNETALEFTGMQAKNIIGHPIWQQPIWQQSPNAKEQLKEAIAKAAMGEFFRSEIDLLGNGGQIVTVDLSLKPVKNETGQVLLLIAEARDISDRKRAESEILKTLAREKELSELRAKFVAMVSHEFRTPLTTIQFSTALLQDYSSNWSIEKRNTHFVRIQLAIKRMTELLEDILVVGKIEANTLQFQPVSLNLEKFCRQMVEEQQLNDSNQHPIALIFTGDNSDAQMDEKLMQQILGNLLSNAIKYSPVGSSVQLHLQCQNGQALFQIKDQGIGIPQADQERIWETFYRATNVGTISGTGLGLAIVKRAVELHGGKIAIHSQKDQGTTFTITLPLICHPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2J9</accession>
    <name>A0A2G4F2J9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-layer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55976">
        <property type="protein sequence ID" value="PHX55976"/>
        <property type="gene ID" value="CP500_008000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLH" evidence="2">
        <location>
            <begin position="312"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="464" mass="50288" checksum="A2777A0F154AAC18" modified="2018-01-31" version="1">MLNIIFAQWRGCSQGRSPAKTTQTNILTTVNTLLTICLLVSMTACANSPNSKAIEESFAADPKLKENPVAFSNPQPATPVDTSTTAKLPADFPTEIPLYPNAQLLQVTEPSASDKNVRLRYESTDPINSIQSYYSTEFGRRNWEIVSRPTPDGQGSLVATRDDLQVTISLSPTQKVGGSTEFGIEYGKKTGEIATNPQPNNSEASPSPSPTPTPANSDSTTPTPSPALKSPKISELDSKIPQQLRQYVADLTQLEVLKVRSKSGANIETGNTLPDANKIATRREYARWLVATNNQIYTSRQAKQIRLAVESSEPAFSDIPKTDPDFAAIQGLAEAGLIPSSISGEAKDVKFRADAPLTREAMILWKVPLDTRQVLPTANIDGVKEKWGFQDAAKIDSQASRAVLADFNNGDLANIRRVFGFTTLFQPKKSVTRAEAAASLWYFGVQDQGLSAKDAAEAKSQPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2P6</accession>
    <name>A0A2G4F2P6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56030">
        <property type="protein sequence ID" value="PHX56030"/>
        <property type="gene ID" value="CP500_007710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="83" mass="9006" checksum="789113C18CADAAC7" modified="2018-01-31" version="1">MLNPAIGNPAIGNPAIGNPAIGNRDYTNKVRLRGLRILKPAPAGFVFAFVCTSQVEICGCSRCSIVYNVCITYQECLYEPDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F316</accession>
    <name>A0A2G4F316_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55857">
        <property type="protein sequence ID" value="PHX55857"/>
        <property type="gene ID" value="CP500_008465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="2"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="456" mass="51918" checksum="6005D05B0AE0D591" modified="2018-01-31" version="1">MKIKVKNLGALKQAEFTLGELTIICGGNNTGKTYATYALFGFLFTWRRMLAIEINDDKIQQLLADGVIRLDIQEYVKQAQQIIAKGCQAYTQQLPQIFAAPAKRFKDTEFQVTLDIKNISLASRFQSTLGSTNVEFFSMTKSQESTELVVTLLVEKEKVKFPNEILKHTIADALKDIIFATIIPRPFIASAERTGAAIFRKELNFARNRLLDEMGQGNNNINPMELLFKAYQDYALPIKTNVDFTRELETIVKKSSFIAENHPDILTDFADIIGGKYTVTRNDELYYEPKGKRLKLSMDESSSAVRSLLDIGFYLKHEAQIGDLLMIDEPELNLHPENQRRVARLFARLVNLGIKVFITTHSDYIIKELNTLIMLNHDKPHLKRIAEEEGYREVELISSNKIKVYIAEETGKTKTNKCQTLTPADIDPEMGIEARSFDTTIETMNRIQEAIVWGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F349</accession>
    <name>A0A2G4F349_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56155">
        <property type="protein sequence ID" value="PHX56155"/>
        <property type="gene ID" value="CP500_006840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013868556" evidence="2">
        <location>
            <begin position="40"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="214"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="340" mass="37296" checksum="EC9E640A9E8E64CA" modified="2018-01-31" version="1">MMKTILASIGKQMLSSKQKVRAIASGAIALSICINSAIAGDPFRASNPQAIGPNTETAFKTMFQQGNYKIAKTQVKQALSSEPNEPLAYAMAASLSYIEQDFKSMDSYAQKTREVAEELSKTNPLRGNIYTAAGHFLEGANVIAKEGTAKGAPQALNKLRVVFQYLDAAEKIAPNDPELNLIKGYMDLMLATNLPFSNASEAIQRLEQKASPRYLAYRGIAVGYRDLKKYDPALEFTNKALVETPKNPEVLYLKAQILSSQAKGKDGKGNNKTLLEEARKNFDAALAKPDQLPRSLVAEIFFQQCKTRNSLDKKSRDCDPMRDKIRDADGIWGPAALPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3C6</accession>
    <name>A0A2G4F3C6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56259">
        <property type="protein sequence ID" value="PHX56259"/>
        <property type="gene ID" value="CP500_006225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="124"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="894" mass="102592" checksum="8E22E8137BE5589A" modified="2018-01-31" version="1">MQENWQSSLKQHLTSEYVRNSTEWVDLNISTSGLLNLTIISDRFVSLSMPQRKQEISTLLQSRVPHLSPGFLSLYTLQEAESLNISPPQVLNAASVNTWQDLAIQAANPQNQTQLPQPELRVPRTVTFYSFKGGVGRTTALTHVASILATRGLKVVAVDLDLEAPGLSTAFNLNPQPKYGIVDYFYERSYLPEGIKPRISIAEIFGEVRVPNATGRLFVVPAGCLNLDYISKVDDLHATTIIDGDKSLWSIFKGEIQEQLKPDILLIDSRTGINQWGALSLIQAADGAIIFLFPNEQNKQGIELLLQSLQSLKNISIDFVFSPVPDITKTGLSKVKNIWDSLHKKIKTATNENYEAETDEDESDSDNDQTLIEDILVIPYLVPIALADSYPVPGMQDYYTKIANLIDEKTDELKRSNVLNIEQRWKIIESLKFPEVNAADRKQDLSLLFQKTTDFEKFLDDTTCLIRGRKGTGKTALYWLFLKHKSIAEKIANGRLDNTKFFSAHGRFQESRPSRTEFQIIHQTLQQHGCPWEDLWRAYLLLRCYQENVLKFPRLAKYRELIKTIKNLPKERWQSENTQALLELSTNSQLRLIVKDAVNILLNEQARDNHQKLWFLYDDLDEDFPEAGEVRHQALTGLFQLVQSCDAERLTEIRFKIFLREDIWNRLIFDNKSHFTGRDIILQWTRIDFLRLALRQAIQSKDFKNLVDKFSPIESIDQASENAIDKALEILWGSRRRRGGKAKYVSRWVYERLTDSSGTTFPRSLSILLEGAKEQELSYEGKLSIQPPNDRLLRSQSLESGLKKASEKRCEEIQEEYPSLAAFFDSLKGQSAILEKEQLQEIWQNSALNIRENFGAFVSFLGEIGIIEWREKEQRYKFADIYVYGFKMDRRGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3E1</accession>
    <name>A0A2G4F3E1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translocation/assembly module TamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_006060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56294">
        <property type="protein sequence ID" value="PHX56294"/>
        <property type="gene ID" value="CP500_006060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007452">
        <property type="entry name" value="TamB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04357">
        <property type="entry name" value="TamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="2248" mass="236556" checksum="C06111B0E43D58C6" modified="2018-01-31" version="1">MTNSPDDKNQLSSHSARRWWRPLLLSGTGLGIFALVGAGAAAWWIPEKLAPLVETEVSQLVKRPVQIGRLERFSPTSLRFGRSSLPATATDPDYASTEAVEVQFSLWQLLLNRTLKLDITLVKPNAYIEQDDKGIWVNLPTFDKPKTPGLFKTEVGAIRVENVGAVLVPSPAVGLKKSLPISVILKNGSAQFSEQNQRVIYEVNGNFTNSDNFSIKADSLLPAAQTNVQLQGQKLPLSYLVQLLRIPDVYFGKGLANGNLTVQLRENKVFGITGTSDFQGVDFALKALKQPILNSGGQLRFQGTNIIVDSLAANYGLIPLKVAGTVETGVNFNLDQAKFNLAANVPPVAVANVVSALEQELGQKVVLPFATAGELKVDAQLTGSVSQPVLAGAIASTKPAIVDRLQFKNISTNFKLERGRVAQAPSSNSSSSIPPFSSLALTLSDILVEPTAGGKIGGKGQIEIALGSQNSRSGLVFDLQAENLPADAIAQIYNIPIPVTVKIGNVSAKTQIFGPLDNIQARVKWQAPQGNFPASGEIRAIGNSVDLQNTVVKIGDAAVNVDAALQGRQWQALIKGDRVNLNSLQPVVPGLSLPPELAGLFSGTAEAAGTLDDLSVNGINARGKGQLNIADSIMNVNGELASGRWQAFGKTEKVALNPLIDISLPFLALGNPNNYTAANLNNLNNLKSKIENLKSLGGQLAGEFKAQGNLDNLTASGINIGGNGKLSIADSNINLKGELVDGKWQGIAETDRTSVSSLVDLGLPLLDVGLAFTADTPQTVANINNLKSKIQNLKSIDGKLSSQFQAAGTLDNFTAKGINVGGSGKLNIGAGNVNFQGELVAGNWQGIAETDRTSISSLVDLGLPFFDIASTFITDNQQIANLNNLKSKIQNLKSIDGQISNQIKAAGNLDKSTIADIAVNSSGKLNIADGTVDFKGKLDGGRWQAVANLDRPILSQLVDLGISFFDVASAKTDNQPTSNLNNLKSKIQNLKSIDGRINGQFQAAGSLDNLTAKGISGSGEARILANGLGAIDTTAKLENGNWQAFLETNDIALANLQQTLKQTGLLTADLPREIDGNLDGKIRLLGTLDNLTANGITANGEGQIRLANGGGIVNAKGRAESGNWRASINGGQIALSRFQKAFEAQRQSLQTPGLVSQAQNLPLLRGLFNGNLNLSGPIASSTGARAGTGAPPLQDVRAGGSFRISELPFLKQPLEAVFNWDGKRVEIENATTPGLTANGIVNVELAGQGLPAISNLDLNVKLSNFNLEALPTEQLGFLRPIGDKKSSDKNVPLRGNVDFVGNLTGTLAALSLVGDVEVRDLAVNQVAFDPVLAGTVNAGLGRSVDLRLAGASDKIEVALNPSFLPTSFLVKRGESVASGQTEGETLRVNLSDFPLAALNLSPGKDAGFGPITGTVSGQVNVPGWKMPLNPATLQASGQIAIAQPAIGYIKGDSFQAEFSYANGNATLNNGIFRQDTGQYLISGNLKAGANPEFAGKVNIQQGNLQQVLAALQYFNLGDLARGLKPPVYGKAADVQTVAVGVPEAPLIEQLQRLAEIEEILKQQQAVKASETLPPLDQLQGTFGGEIAVGGSLQTGIKAQFNVKGDNWQWGKYVAQQFSIEGGFQDGILTILPLEIRSGKSAIGFSGQLGQKAQSGQLRVENLPVEELAKLVELPFVDVTGNLNLRANLAGTLANPQLAGELSLQDGTLNRELIKKADGSFSYSNARLNFGGSALVTQTEPIEVQGSLPFELPFATVKADSNQIDLRANLQNEGLAIINVLTPQVAWISGKGQVQIRVSGTLERPVAEGSANFENATVRARAFPEPLTGLTGAVRFEGDRIRVEGIRGQLKQGEIVAQGVIPLSRAFAEGDADAATPLAVNLDKLGLDLKGLYRGKVVGQVQAIGTALRPQLTGKIELYDGEVFLPSGGDSTRLVSAAAASPETPSASVAVSPSIGTPTATSSSPSFEVGLNNLQLNLGRGIKVTSAPILSFGATGGLTVNGTLDDIRPEGTIRLTSGAVNLFTTQFRLDRGYPQTATFVPSQGLDPTLDVRLATSVQEVTRFRTPGNSVASEIADEPTGFGNVRSVQIQALVQGKASQLSDSLELRSSPSRSSIEIVALLGGGFVQTLGRGDSTLAIANLAGAGLFGNLQSVITNATGLTEFRLFPTRIGAGETQTSSSGSAAGSLGVGLEVGGDITRNLSATIIRVLSANQPTEFNLRYRLNDQILLRGSTNFQGENRGTIEYELRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3F0</accession>
    <name>A0A2G4F3F0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease VapC</fullName>
            <shortName evidence="5">RNase VapC</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vapC</name>
        <name evidence="7" type="ORF">CP500_006115</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56304">
        <property type="protein sequence ID" value="PHX56304"/>
        <property type="gene ID" value="CP500_006115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 5" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="6">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="14981" checksum="A56352E311B9E8DE" modified="2018-01-31" version="1">MNVLVDSSVWSLALRRNTTNDAIAIVKVLHDLIGDGRVVLLGAIRQEVLSGVRYKEQFARLQEYLRAFPDLELTTEDYELAAEFFNTCRSNGVQGSNTDFLLCAVAHRRGYSIFTTDKDFENFRSHIPVILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3G2</accession>
    <name>A0A2G4F3G2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56017">
        <property type="protein sequence ID" value="PHX56017"/>
        <property type="gene ID" value="CP500_007640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="14062" checksum="58E6A79439954A9C" modified="2018-01-31" version="1">MFIVTTKRILIIDDAEDIREVAQVSLEVVGGWEVMTASSGREGVAKALAQQPDAILLDVMMPDQDGPTTFLQLQANSATQHIPVILLTAKALAGDRRMFADLGVASVIAKPFEPMFLASQVAKVLGWDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3G4</accession>
    <name>A0A2G4F3G4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GP-PDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56310">
        <property type="protein sequence ID" value="PHX56310"/>
        <property type="gene ID" value="CP500_006150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="2">
        <location>
            <begin position="173"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="507" mass="55141" checksum="4A136DE36DD13B9F" modified="2018-01-31" version="1">MAVTEFFLLTNSDDNFTITPGSLKGILGGISALGGNDNITGSSDSEAINGNSGNDSLSGGSGNDTLIGGQGNDILLGGDGNDFLSGDKGLDTLTGGAGNDTFLLRRTQGADVITDFSSGDRLTLENQLQFSDLLITSTGLNTAISLRDGTLLATINGVPTINQNNFVELPRRPLIIGHRGASGYRPEHTLASYELAIEMGADFIEPDLVSTKDGVLIARHENEISGTTDIAKRPEFADRKRKKTIDGAEVEGWFTEDLTLAEIKSLRARERLPELRGTAFDGQFQVPTFQEVIDLAKRKSAEKGRTIGLYPETKHPTYFKSVNLPLEQRLVQVLSANGYTKRTDPVFIQSFEVGNLKELNRLTDLPLVQLMDDFAEKPYDFVVSGDRRTYRDLMTTQGLAEIKTYADGIGPWKRTIVVEGADKKLQPANSLITDAHLAGLLVHPYTFRNESPTYVASEYGGNPALEYEQFYRLGVDGVFSDFPDTAFNAAARLYPFSTVDSLKGVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3G5</accession>
    <name>A0A2G4F3G5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Colanic acid biosynthesis acetyltransferase WcaF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56275">
        <property type="protein sequence ID" value="PHX56275"/>
        <property type="gene ID" value="CP500_006320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="222" mass="24752" checksum="383108129A4DFF31" modified="2018-01-31" version="1">MTNYTPTPDPEPQKPIANFPNPEINYHSISDNQPNIFTGESLVDLRKYDQSKFDRGRPGWVIVLWWFVQAIAFPLTPHPVNCIRRWLLRLFGAKIGFGVIIRPTARFTYPWKIEIGDYSWIGDDVVLYSLERIAIGKHCVISQKSYLCTGTHDPQDPAFGLITASVIINHGVWIAADCFIGPGVEIGANALIGARSSVFKNIPAGFVCMGTPCSPSHPREIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3K2</accession>
    <name>A0A2G4F3K2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56326">
        <property type="protein sequence ID" value="PHX56326"/>
        <property type="gene ID" value="CP500_005950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="11"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="334"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="678"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="856"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1168" mass="133793" checksum="E1A451DBCC6F6A41" modified="2018-01-31" version="1">MSTASQTPQVSVIIPAYNGDRYIVQAVESALSQTFTDLEIIVVDDGSTDQTHQVLEPYLHRIRYIYQENQGVAAARNRGIKEAKGDLIAFLDQDDFFFPNKLAAQVALFRSSPSLGIVNSGWRLVDEQGNAISDIEPWQYFPKLDLETWIVQMPVLPSAMMFSRKWLEIAGGFNSEFDSVDDADLVIRLAVLGCEAAWLPQVTVCYRQHDKNVSIKKALQQANLFIKLKHNFFNKLDLPQPIRDLKNPAFYEALTWMAWQLYYSGYPVAAVEYYQKSLPYTPYSATKTVIDWINRLAYISQAYGFSIDLQSLRNLPQWQQLMSNILPQKTVRVSVIIPAYNCDRYIVRAVESVIKQTYQDWEIIVVDDGSTDTTSKVLAPYLDLIQYVYQENQGAAIARNHACELAKGEFLAFLDADDFFLPEKLEKQVACFDADSSLGMVQNGWLIVDENGKDISPIMPWKEVDKLDLETLVLYKFVRPSAMMLRREWWERLGGFDPRFPPTEDLDFALRLALKGCKSVWLKEILTCYRQHSTNLMSGGTKMMKNMEIVMEQFFARPDLPKHIRDLKQAERYKCLVWIAWRMYRDGYLPEMVESLEKSLHYTRLTGTETVFNWLETFKGVSEQYGHNFDAYALTNLQEWQDIVVLAVNNPYQFQPASISIYQPQKARVLLYAEDHGVGGLAQFNHSLMCRLAADGYRVTSVQTQTSNPLITEQQQLGIEHIWLEFDTMKEFSRIAYNLADAEKIYAQSQPDLIIFSDGWPMANFAAKEVAIKQKIPYIITLGYVDRTYEIFQRGDEIPYLDAVSYQYGLSRAAVAVSHENLALFKSLFKQPLEQGKVIYYGRPKNYFEPPNLSTRQRLRQEQGIPEDAIVCFTAARLTPIKGYQYQLQAIAQLKQLPIWSQLYFVWAGPGSATHDNMEPELRANVSKLGVNEQVKFLGQRWDIADWLDASDIFILPSEAEGMPLAIMEAMAKGLPVIATAVSGIPEELGDTGRLLPNPQIDPKGTVTELVETIKIWAENPELRQIAGQGCKARAQELFAEARMLQEYSEVIEQVLLVDNHSDEFYINPKVQKQMERVDKCLHYNYLVWKAWYAYDRGDISGMVKNLQSSLTCTPLLTTETILNWLKSFANFYAEKDLQLDTYALTKLEAWQQLIESIQGFEVLLSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3L7</accession>
    <name>A0A2G4F3L7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">KGK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56338">
        <property type="protein sequence ID" value="PHX56338"/>
        <property type="gene ID" value="CP500_006015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014971">
        <property type="entry name" value="KGK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08872">
        <property type="entry name" value="KGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="152" mass="17567" checksum="BC19805F45E35169" modified="2018-01-31" version="1">MDEKVKINTSYEILDGDDDVLLLGKATFTIRHLKELATSKFHYMLFSLKAEKESQKQSIYYWMTELCINEETKIMGGDINWNSPQEGIDCQILKIGSKGWQKGKVQIEVNKNIKSGETQTSIKFCPDEPLEQKSPLDDIRQSEEYKKLLENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3P3</accession>
    <name>A0A2G4F3P3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Divalent metal cation transporter MntH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mntH</name>
        <name evidence="5" type="ORF">CP500_005690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">H(+)-stimulated, divalent metal cation uptake system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRAMP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56404">
        <property type="protein sequence ID" value="PHX56404"/>
        <property type="gene ID" value="CP500_005690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00221">
        <property type="entry name" value="NRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01197">
        <property type="entry name" value="nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="371"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="434" mass="47148" checksum="EB2AFCB6CECDF8D8" modified="2018-01-31" version="1">MTHSENRPSLPEVHRSVPIPNSKGFWRKMLAYAGPGYLVSVGYMDPGNWATDLAGGAKFGYALLSVILLSNLMAILLQSLCVRLGVATGRDLAQACRDYFSPRVSFLLWILCEIAISACDLAELVGSAIGLQLLFGIPLVWGVCITALDVIMVLFLQGKGFRYIEALVITIIAIIGGCFIAEMIFAKPDAGGVLLGYVPSLEILQNQGMLYIAVGILGATVMPHNLYLHSSIVQTRAWQETSEKKWEAIKFGTIDSTVALSIALFINSAILILSAATFHFSGYQEVAEIQDAYKLLSPVLGVGSASAIFAFALLASGQNSTLTATLAGQIVMEGFLNFRLRPWLRRLLTRLIAIVPALIVIILFGEGSTTNLLVFSQVILSLQLSFAVIPLVMFTSNRRLMGEFVNPFWLQAVAWLVASIIVALNGWLLLQTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Q4</accession>
    <name>A0A2G4F3Q4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA interferase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Toxic component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PemK/MazF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56414">
        <property type="protein sequence ID" value="PHX56414"/>
        <property type="gene ID" value="CP500_005630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR033490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="12481" checksum="BC2A27D27869AB9C" modified="2018-01-31" version="1">MGSIWIARFDPSVGTEIRKTRPALVISGTLFNERRSKITVLPFTSARPHDTRISAAVILVPASPQNGLNADSLLVCVDPMTFDKTRLVQQLGQLESELFSQAQEILQRYLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F446</accession>
    <name>A0A2G4F446_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HEPN_RiboL-PSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56519">
        <property type="protein sequence ID" value="PHX56519"/>
        <property type="gene ID" value="CP500_005035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041519">
        <property type="entry name" value="HEPN_RiboL-PSP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18735">
        <property type="entry name" value="HEPN_RiboL-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN_RiboL-PSP" evidence="1">
        <location>
            <begin position="42"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="354" mass="41811" checksum="B627D5B04B6D85DC" modified="2018-01-31" version="1">MNIQSLENFKRELNQIKEYLKHIQYVNDLTAYAIIDTDNGQIKELLNRLKEHDRGFRTDKRIFEYKASIISLYGLLEKYVEIWIKEYLDSLSKVVPEYNQVDEKIRINHFELSLKLINTIATRESAKYQHLKKEEVLKKLNECIVNPSNYQINTEAFVLLSGNLKHNKIVEIFNKLSLDLNDELLKNEELNNEIGLTPERISTIGKDILYNKINDLVERRNQIAHGSENVEDIKSISELEPYIQFLEKYCQAIFQALFEQFIKQESIHTFQKIEKVIKIFNDKILAFEIENYTIKVKDMLIIETKEGRFYKKPILTIRLDDQSYPELAVIEKTNIGISVEPKIKPNQTFYIIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F497</accession>
    <name>A0A2G4F497_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56569">
        <property type="protein sequence ID" value="PHX56569"/>
        <property type="gene ID" value="CP500_004800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022789">
        <property type="entry name" value="ParD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03693">
        <property type="entry name" value="ParD_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9446" checksum="40A5D2E947BE0BE8" modified="2018-01-31" version="1">MNVVLNRELEQLIQSELDTGKYENVEAVLREALKLLSERNSRLILARKVKDLFEKTQGIPEVQEITEEEIAAEIEAYRRCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4A7</accession>
    <name>A0A2G4F4A7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56579">
        <property type="protein sequence ID" value="PHX56579"/>
        <property type="gene ID" value="CP500_004865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8518" checksum="05EFC485CFC35A39" modified="2018-01-31" version="1">MSKTTQTSQFQQALEAVEVLSLEDQAMLLDILQNRLRQQRRNELLKEVAEVRQEYAEGNVKFGSVADFMAELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4B3</accession>
    <name>A0A2G4F4B3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_004505</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56602">
        <property type="protein sequence ID" value="PHX56602"/>
        <property type="gene ID" value="CP500_004505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037359">
        <property type="entry name" value="NST/OST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10605">
        <property type="entry name" value="PTHR10605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="104"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransfer_1" evidence="4">
        <location>
            <begin position="373"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="611" mass="71074" checksum="F51C7667E3549C8A" modified="2018-01-31" version="1">MNNEYHNLGNALQESGKFDEAVIAYQKAVELNPDFSWSYHCLGDVLVKLERWEESIVAYNKAVELNPEFSWSYHNLGDVLLKLEQWEDAAAAYRCEIELKSDFAWSFGNLGDALIQLKKWDEAINVYLKAIVIDRNLPEIYEKLGYVLRQTESDLNSVFQQCQLPLVPENREFYLDLGRSLARCDRPKSAIIFFKLLLTNEPNCDMWAAQLGEFLQEQEKCDRALASCRATVAQKPDDCWSYYNLGAVLSHQKKWDEAATSFLKAIEINPDFYWWFYYNLWEVLVKQNKLDEVASLYRGVVEAQPEAFWPYLNLGEALTRQGKIEEAICCYQTVSYQQTFGAIISKDTGKMPVPQNTQDTGKMPVLQNTVKVPDFIIIGSQRCGTTSLYTYLAQHPQILTPIKKEMDFFSWHFDRGIDWYLAHFPPMPVGEQFLTGEASPSYFDSLAAPERLYSAFPEVKLVVLLRNPVDRAISQFYRLTELNWEVRSFDRAISDEIARLAQNPAYIIGEEPGNYLARGRYIQFIKNWLDFFPKEQLLILRSEDFYAGAATTVKQVLEFLDLPEYQLPEYQNANPGSYQPISDSMRDRLSDYFRPYNQELEDYLRRKFDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4E3</accession>
    <name>A0A2G4F4E3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fused response regulator/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_004400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56653">
        <property type="protein sequence ID" value="PHX56653"/>
        <property type="gene ID" value="CP500_004400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="10"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="557" mass="61861" checksum="E41FF5AD398154B3" modified="2018-01-31" version="1">MSRGDGSKLKLMVVDDEPDNLDLLYRTFRRDFQVYKADSALSALEVLDEQGEMAVIISDQRMPEMNGTEFLGKTVEQFPDTIRILLTGYTDVEDLVEAINSGQVFKYITKPWNPEELKLVINQASETYKYYKQRSVELRRALRKESLFNEVMGVIRGSLDYSSMVQTIVQTVGKTFEATHCMLRPVEGDRLLPSTFPYQAQTAEPSSFSFNENLLVQAVASRQTQRQSGSQPDGNSVEIAVPLTYQQDILAVLALCQLDNSNTWSPEDIELIEGVGAQAALALSQAKLYQRTLDLAQQMQNELEVARQIQTNLLRQSWPDFETVRVQACCYPAREVGGDFFEVYVHSQGDIWIAVGDVSGKGVPAALFMASAISVMRRELSQEISPEPSQVMTNMNSSMADDLIGNNHFITMVVARYTPSTGHMAFANAGHIYPIVWSHSEVKAQAASGSTPVEPNFLKARGIPLGILPVWKGKSGAIDLKSGDVFLLTSDGITEATVMSKAVPGEEQTRSMLQQEGLWELLIEEPGSFNLDNLLVHIRADNPVQEDDQTILSLEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4E9</accession>
    <name>A0A2G4F4E9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56664">
        <property type="protein sequence ID" value="PHX56664"/>
        <property type="gene ID" value="CP500_003990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019664">
        <property type="entry name" value="Uncharacterised_Ycf51"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10726">
        <property type="entry name" value="DUF2518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="18773" checksum="064AD766A4867F00" modified="2018-01-31" version="1">MNVNSTFLMYAQWAGILTAILAVVTVLAFILQWGFRFRLVGVTSFMAVIAASIFGLGLGLFSRTQIAGAVRYSLVYDTGGAQTVVTVPPSITESELEATMQQAAADLYSPGRSGSGRDYMTIRVRTIVHPEPGVSQPLFLGEVRRSLATRYDDKMAIEIFPDKVAILKKYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4M5</accession>
    <name>A0A2G4F4M5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_003745</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56734">
        <property type="protein sequence ID" value="PHX56734"/>
        <property type="gene ID" value="CP500_003745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025592">
        <property type="entry name" value="DUF4347"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14252">
        <property type="entry name" value="DUF4347"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="DUF4347" evidence="3">
        <location>
            <begin position="11"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="4">
        <location>
            <begin position="791"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="4">
        <location>
            <begin position="896"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="4">
        <location>
            <begin position="998"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="4">
        <location>
            <begin position="1116"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="4">
        <location>
            <begin position="1220"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="4">
        <location>
            <begin position="1322"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1417"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1422"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1488"/>
            <end position="1502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1738" mass="173423" checksum="1588F7BA371994B3" modified="2018-01-31" version="1">MEFDKTRNQQIVFVDSKVKDYPILTESTHPDTKVIFLKGDRDGIEQITETLKTRENIAAVHILSHGAAASVQIGATELNLSNIETYRDRLETWFALPAEENSNSRITAKPEILLYGCNVAATEAGIAFVQRLSQLTGAEVAASDNLTGNAALGGDWELEVSTGKIETALAFSQEAREAYSGVLGTFTATDFTSLNNAILFANVLTDADDINITAPITFSAGQVLPVITNPVNFVGSTTTGITINGGGNSRLFFVDTTATVTLSNLTLQNGAATGKPGTLGGGGAAGLGGALFINKGTVKIDSVTFASNKATGGAGATGNGGAGGNSDLSTGSPGGTPGAAGAGGLGGTPNGTGGDGGTAGGGSSGFPGGAGGTGGIGGTGGATNGTGGNGSVGGTGGTGIFGGGGGAGGTGGAGGPGVGTGNGGNGGKGGAGGAGGFGGGGGPGGVGGAAGTGTTAGAAGTVGVGGAGGFGGGGGAGSTGGASGGGGSGAGGTTGGGGGSGLGGAIFLNTGGILNVSNSTFSANTVTGGAAGGNGTAGQGLGGAIFVNTGATANLANTTITLNTASTNSGGVSYAGTFNANNTIISGNTGGANPDITGNVVSTGANNLIGVAALLGPLQNNGGFVSTHALLVGSTALNAGNAATALNAITGAALTTDQRGTQFNQPFARSVNGAVDIGAYEYGPTVTGQIFNDSNGNAAKDGTEATVTTPVQNFVVYVDDNNNSSLDSAEKRVTVATGGTYTLLDTKSNSPVREQAVTNWQQTFPKATATPYNTGIADSNSKDFGNFQSMTINGLIFDDKNGSGVQDSGDTGLDNIPVNLINSVTGATITTQNTTATGTYSFPNLGPLTDGATYRVREVVPTGSTKTTVDPADIPLQSGLTVAVPNFGNFKNITISGTKFDDKNGNSVLDAGEVAPATPFDIQLLNAAGAVVKTQTTATTGNYTFTDVGPGTYTLKEVAQTGWQSTLAPAGSITASSGVNITNTAATPTNFGNFLLGKIGGIKFNDLNKNGTQDLPAEQPLGGWTIYLDANNNGIQDVVPAETGTNAAVTDVTGKYQFTNLVAGTYNVREVPQTGWTQTTPLASAATPTLSGAFTIPVASGTDSQNNNFGNFKPNSISGIKFNDINKSGFLDAGEAGLANWQFFLDTNNNGTLDTDEPKADTDPAGNYKFLNLPAGTYKVREVPQTGWTQTTPNPADITVTSGQDIPNINFGNFKSSTISGQKFSDANNNGIKDTGELGLPNWQIFLDINQDGVFQQTEPTTITDTNGNYTLVNIPVGTYQVREVQQNGWTQTTPNPAPVTIVGGNSITGVDFGNFLPQPGTIRGLKFRDGNNNGTQDSGELGLPGFQIQLTNVTPGVVAPTPVTATTDNSGNYLFTNLTPGTYRVREIAQTGFTQSTPNPADIVLASGATVSNINFGNFPTPTPAPTPAPTPIPTPAPTPAPTPAPTPAPTPAPTPAPTPAPTPIPEPTTPLSPQTTDLVRPNDFPRVETPNQSASPIGGNVINGPNGDDTIVGSAARDSIFGLGGNDLIFGRQGGDYINGNIGNDTVYGGIDNDTLLGGKGFDLIFADRGNDIIYGNRGNDSISGDEGDDLSYGGKGDDVMLGGIGNDVLFGDQGNDTLCGGDDNDSLLGGSGDDVLFGDFGDDLLFGGLGNDTLIGGDGSNSFLLTDGSGLDTIVDFTQGVDVLVLAGGLDFGQLSFTQTNGSASISLAGTGEVLAILKGVRSSLLTAQDFNVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4N8</accession>
    <name>A0A2G4F4N8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1,4-dihydroxy-2-naphthoyl-CoA hydrolase</fullName>
            <shortName evidence="1">DHNA-CoA hydrolase</shortName>
            <ecNumber evidence="1">3.1.2.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">DHNA-CoA thioesterase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26309"/>
            <dbReference type="ChEBI" id="CHEBI:11173"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58897"/>
            <dbReference type="EC" id="3.1.2.28"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; phylloquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 7/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.28" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56457">
        <property type="protein sequence ID" value="PHX56457"/>
        <property type="gene ID" value="CP500_005505"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00995"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER01033"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042372">
        <property type="term" value="P:phylloquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02101">
        <property type="entry name" value="DHNA_CoA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022829">
        <property type="entry name" value="DHNA_CoA_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="137" mass="15350" checksum="283B47A2DB030DCB" modified="2018-01-31" version="1">MPFTYTRTVRFQDTDAAGVVYFANVLAMCHEAYEASLTALGINLKAFFSNPDRALPIVYATVDFYRPMFAGDQLTIQLIPKQLGAGEFEIAYQVFSGEITGKSAAKALTKHVCIDAVSRTKKQLSEELIQWLRQFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4U3</accession>
    <name>A0A2G4F4U3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56745">
        <property type="protein sequence ID" value="PHX56745"/>
        <property type="gene ID" value="CP500_003805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8283" checksum="ECCFC0C8D9D8F809" modified="2018-01-31" version="1">MGCRCWIKCCWIGLRFLRYKFYPWITLTIAPLKILAASGINRTHEKIRYMSAIGKINFAAVYELLNELLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4V5</accession>
    <name>A0A2G4F4V5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyridoxal phosphate-dependent aminotransferase</fullName>
            <ecNumber evidence="5">2.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_003785</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56741">
        <property type="protein sequence ID" value="PHX56741"/>
        <property type="gene ID" value="CP500_003785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="30"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="389" mass="42767" checksum="CA1F9A44810151C4" modified="2018-01-31" version="1">MKINATRMQSVQSPIIPVVGELIRQNPGTISLGQGVVSYNPPPQSFAKIPEFLANPDNHKYKAVEGIAPLQDAIAAKLKADNNIEINNTNSIVVTAGSNMGFINAILAITSAGDEIIIQSPYYFNHEMAIIMANCHPVIVETDENHQLNIDAIQKAITDKTRAIVTISPNNPTGVVYDSEALREVNELCRQHNIYHISDEAYEYFTYDGVKHCSPAAFSDSSEYTISLFTLSKAYGFASWRIGYMVIPEHLLDSVRKIQDTILICPPVISQYVALGALQVGREYCDNHVRAIASVRQLVLNELNTVQNLCTISPACGAFYFFLKIDTQLDTMELVEKLIREYQVAVLPGTTFGMDSGCYLRVAYGALERETAAAGISRLVKGLKTIIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Y3</accession>
    <name>A0A2G4F4Y3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7,8-dihydroneopterin aldolase</fullName>
            <ecNumber evidence="1">4.1.2.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">folB</name>
        <name evidence="3" type="ORF">CP500_003550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde</text>
            <dbReference type="Rhea" id="RHEA:10540"/>
            <dbReference type="ChEBI" id="CHEBI:17001"/>
            <dbReference type="ChEBI" id="CHEBI:17071"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="EC" id="4.1.2.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.25" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56810">
        <property type="protein sequence ID" value="PHX56810"/>
        <property type="gene ID" value="CP500_003550"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00534">
        <property type="entry name" value="DHNA_DHNTPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006156">
        <property type="entry name" value="Dihydroneopterin_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42844">
        <property type="entry name" value="PTHR42844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00525">
        <property type="entry name" value="folB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FolB" evidence="2">
        <location>
            <begin position="4"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="13317" checksum="00E940132AB7F28B" modified="2018-01-31" version="1">MDSIQLTGIRCYGYTGYLPEEQVLGQWFEVDVTLWLDLSQAGKSDDIEHTLDYRSAISMIQTLVKESKFLLIERLADTIAQALLQLPLVQKVKLQLSKPAAPIPDFGGRITLEITRTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F518</accession>
    <name>A0A2G4F518_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56838">
        <property type="protein sequence ID" value="PHX56838"/>
        <property type="gene ID" value="CP500_003310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="204" mass="23286" checksum="22FF0145F938E26D" modified="2018-01-31" version="1">MSIKKSHYEALLAQYSESSNALELLKKYRVYMEMIPSIRRIDDSLIAIPLPIARLREGVSYARSSGASISPGQAVCLPCDLAILMCDPEWKVKIGVEILIFIHRPDEEFSELLGRWRQCEVWLDKDYEWVMPHRYRHIFSDQAEAIHPLFVLFDETPELIQRGLMGAGLPFVVESFDSGIEEAEEEEFLGSGELGSLGEESYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F536</accession>
    <name>A0A2G4F536_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alanine racemase</fullName>
            <ecNumber evidence="3">5.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_002735</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-alanine = D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20249"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="5.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alanine racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56913">
        <property type="protein sequence ID" value="PHX56913"/>
        <property type="gene ID" value="CP500_002735"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00042">
        <property type="reaction ID" value="UER00497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030632">
        <property type="term" value="P:D-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01201">
        <property type="entry name" value="Ala_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011079">
        <property type="entry name" value="Ala_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020622">
        <property type="entry name" value="Ala_racemase_pyridoxalP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00842">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01005">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00492">
        <property type="entry name" value="alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00395">
        <property type="entry name" value="ALANINE_RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_C" evidence="6">
        <location>
            <begin position="270"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for D-alanine" evidence="3">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for L-alanine" evidence="3">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3 4">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="399" mass="43441" checksum="F17D95517124F0DF" modified="2018-01-31" version="1">MLNREQTPIAPPTKECPQMVQYDGYGGLCQRAWVEIDLAALTHNIKQLKNILSPNTQLMAVVKADAYGHGAIAVSQTVLQAGASWLGVATIPEGIELREAGIEAPILVLGATYTTEQVKAIAHWHLQPTICTVKQALIFSEVLATLNQSLPVHAKLDTGMSRLGTPWQEATEFVQLIQRLPNLKLASVYSHLATADSPDQTIMLQQHEKFKQAIAQIKIAGINPDRLHLANSAATLTNPNLHYDLVRVGLANYGLYPAPHLQSAIDLKPVMQVKARVTQVKTIEAGTGVSYGHQFVAEQQTQIAVVGIGYADGIPRNLSNKMQVLIRGNFVPQVGSVTMDQLMLDVSAIPDLEVGEVVTLLGKDRENQISADDWATILGTISWEILCGFKHRLPRVAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F542</accession>
    <name>A0A2G4F542_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56607">
        <property type="protein sequence ID" value="PHX56607"/>
        <property type="gene ID" value="CP500_004535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7549" checksum="C5C9038824AE1D2D" modified="2018-01-31" version="1">MTQTLLPQFTIAELVFQVYHSGLLTQTHRQQLMTVLLNDCLTEEDQTAINRLLHAVRRGWLKVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F561</accession>
    <name>A0A2G4F561_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56886">
        <property type="protein sequence ID" value="PHX56886"/>
        <property type="gene ID" value="CP500_003170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005593">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018970">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273">
        <property type="entry name" value="PTHR31273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03894">
        <property type="entry name" value="XFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09364">
        <property type="entry name" value="XFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017245">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="392"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="737" mass="78691" checksum="F3B822B824F9F799" modified="2018-01-31" version="1">MTATTPKPTSATPAFCEGIQYFSETVPGFETYGKAPAIAQGSKSIADPADPAAVFQTMLAADALRYLTLQVTASKASGHPGGFASQAEAYAALVMLGHKNIVTEVGHHAPGFYSAMFLDRSLEDMEIVNVQQVRDKFREKDGLLGHLSGFIPGLLAPAGPLGQGQHFAMSGALLHRDKLFAFTMGDGGMGEPYPMSSMGHFHTAYPSVTNFLPVLVWNGYSQEHHSMVSTKTNAEMIAYWQGNGFEEIILVDAKEFDDGSQAGDYIDSTAFSLEQRMAFTKAVLQGVDKAAKSALGGKLTVFIIKQLKGAGVHALGAKSHNLYPKDTLDAPHIISALKERALTVEAWQLVRTNAERAGGGPAAKTVVTEFELPLADLGELPLEEFAVGGEAKVSTTAMGRLVGKVGERDRTFIVTNADGNEASGIANINQALKIIHPTTDDLYNQGPNGQVYEPLSEDACAGLAVGLCLFGARSLWCSYESFAINGLPIWQTVTQAMAELRRPTPATVTLFTAGALEQGRNGWTHQRPEIEAYFAAMMRNGNVFPLFPPDANSIQACYDWALTAKNKGIVITASKSPLPIRTTFAQTRQGLEDGAIVLQEIAGSKKVVFAVIGDMSLIPVFEAAASLEKSGIGSRIVSIINPRRLYRPTDVAWDTCSEADGGFLSDDKFAEMFGGDALVGVIGGASGMLEPVMLRSNCPRDTFAWKRGETTASAGQLMAFNGLTAEALTKRAIALVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5C9</accession>
    <name>A0A2G4F5C9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2237 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56935">
        <property type="protein sequence ID" value="PHX56935"/>
        <property type="gene ID" value="CP500_002860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018714">
        <property type="entry name" value="DUF2237"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37466">
        <property type="entry name" value="PTHR37466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09996">
        <property type="entry name" value="DUF2237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="123" mass="13210" checksum="553D17DB14E07176" modified="2018-01-31" version="1">MVTEATNVLGGKLETCCTSPMTGYYRDGKCNTGGGDYGAHTVCVLLTAEFLQFSKSRGNDLLTPVPEYNFPGLKPGECWCLCASRWKEAMDAGCAPGVVLSATHVLTLEYVSLNELQQHAADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5E8</accession>
    <name>A0A2G4F5E8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cytochrome D ubiquinol oxidase subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56931">
        <property type="protein sequence ID" value="PHX56931"/>
        <property type="gene ID" value="CP500_002840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="355" mass="39809" checksum="90ADE922E3CB2A51" modified="2018-01-31" version="1">MIPSISGQAFESLQPEVIDLINHLPMLKHKEWIGRSLSTIVRMAGEDLDRLDWKIISSSLRDMENAFQMFYPYRHVRKIVMFGSARVSPESPEYQMAKDFATAITQQGFMVITGGGGGIMQAGNEGATAENSFGLNIQLPFEQGSNPFIEGDRKALNFKYFFTRKLFFLRESDALALFPGGFGTLDEAFECLTLTQTGKFGPAPLVLLDRPGGDYWHDWDAFVQKQLRGRGLISADDRSLYTITDNVEVACEAIASFYLVYHSCRYVNEKLVIRLKSELSDVSVEQLNADFSDIVVTGKIEKSQALPPEIGDETFDLPRLTLHFNQRNVGRLYQLIATINQMGATSPEAAHPEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5T8</accession>
    <name>A0A2G4F5T8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="13">ATP-PRT</shortName>
            <shortName evidence="13">ATP-PRTase</shortName>
            <ecNumber evidence="5 13">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">hisG</name>
        <name evidence="15" type="ORF">CP500_001920</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Heteromultimer composed of HisG and HisZ subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">Lacks the C-terminal regulatory region which is replaced by HisZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the ATP phosphoribosyltransferase family. Short subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="5 13"/>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57061">
        <property type="protein sequence ID" value="PHX57061"/>
        <property type="gene ID" value="CP500_001920"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13595">
        <property type="entry name" value="PBP2_HisGs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01018">
        <property type="entry name" value="HisG_Short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024893">
        <property type="entry name" value="ATP_PRibTrfase_HisG_short"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 13" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="14">
        <location>
            <begin position="52"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX57061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="214" mass="23315" checksum="F6C56A45E9773DE7" modified="2018-01-31" version="1">MITVALPKGGLLADSIRLFKSVGLDFSAFLDSSNRQLQIYDPTGTAKALLVRTHDVPVYVEYGQADLGISGYDVLREKQPKVASLIDLKFGKCRLSVAVKESSSYRRTVDLPPHGRVASKFVHCAREYFHNLNLPVEIVPLYGSVELGPITGMSEAIVDLVATGKTLQENGLIEIDVLFESSAYLIGHPLSYRLNSGGVNEVIGKLREQVLAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F618</accession>
    <name>A0A2G4F618_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplO</name>
        <name evidence="10" type="ORF">CP500_001730</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57141">
        <property type="protein sequence ID" value="PHX57141"/>
        <property type="gene ID" value="CP500_001730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="9">
        <location>
            <begin position="27"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="15548" checksum="5223E3C6ABE6B6B6" modified="2018-01-31" version="1">MRLQDARPKAGSTKRGRRLGRGISAGQGASSGKGMRGQKARSGSGTRPGFEGGQNPLYRRLPKLKSFPNVNRKEYTTINVSKLASLPANTEVTLTSLIQAKIVNSDNGPLKILGDGELNVALQVRAKAFTAGARTKIEAAGGSCELVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F637</accession>
    <name>A0A2G4F637_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57253">
        <property type="protein sequence ID" value="PHX57253"/>
        <property type="gene ID" value="CP500_001020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="324" mass="36966" checksum="568ED6E76B684B4F" modified="2018-01-31" version="1">MMISVVIPTYNREQTLRETLANAVAQDYPNLEILVIDQTRIHESETQVYLELLANSNQIRWFRVNWANLPGARNFAVRRAVGDIILFIDDDVELPKGFLTAHASNYLEKPDVGCVAGRVFDRMKLDLSGGDLAIEYLPPEAMDAGIAWYFIDLVHTVKPQQVLSARGCNMSFRKQVFTEHGLSFDERFAGSAVREESDFCLKLRSTGFKIWYDPNACLVHLGEESGGCHDVSTRSIEYQVTFYHNHFLMGLKNLTVFQCLRFFAKLFDCHVLGNPPCYKTRSPIKIITRFAFYILGFISAINTTIQSLWNDGQIYTNQDNINPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6G7</accession>
    <name>A0A2G4F6G7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57348">
        <property type="protein sequence ID" value="PHX57348"/>
        <property type="gene ID" value="CP500_000785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7816" checksum="F532137AF5491408" modified="2018-01-31" version="1">MVYGVLWDILGAIGPWTQADAVFDDEVGKTIRFLAIVLCNNLLHKFLLEGNGWNRFRRRKLKLVLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6H9</accession>
    <name>A0A2G4F6H9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1822 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57301">
        <property type="protein sequence ID" value="PHX57301"/>
        <property type="gene ID" value="CP500_000510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014951">
        <property type="entry name" value="DUF1822"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08852">
        <property type="entry name" value="DUF1822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="417" mass="45731" checksum="2FC3A947ED2B10B4" modified="2018-01-31" version="1">MTASTILPPFAVSLELTAHRWAEHLAAQQTSPAKGKRVYLNSLAVFAVSRFLESMGIETDLQAGDSANLALCGLLNATDLVLPEMGSIECLPVLPGEQFLNLTGEFREDLIGYVAVQFAERLDAVQLLGFIKNNQAEELLEQVAIADLLPLDYLIEQLNELEFKKAIEQPSILQEFSLQSTIIDELSQRLRNFWGERAQAGWQTVEAIESLWTAASPARAGFRSKDSDRPQSSDSEAAISALIFLLQTNSEELILRQTVNLLGEIGTDSPELIAALTELLHSTNDLETRWQTAIALGKIAPNHPEAAVRKAKLIDLGMQLGTASVSLIVGLMPKSENEVEVFIQVQPTGDRQVLPPQLKLTILSSEGDTCLEVEARTDSQGIGIDDCIQLRHSFPIGSRFRIKISLENTSVTEDFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6K2</accession>
    <name>A0A2G4F6K2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57117">
        <property type="protein sequence ID" value="PHX57117"/>
        <property type="gene ID" value="CP500_001570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="10853" checksum="BFA2F5F55327EBE9" modified="2018-01-31" version="1">MIYLRMKQPCPNPPSQGGDKIPIKVPLLKGDLGGSRLRLKATFIMGFRLKLTPMPMPHAPCHAPCHAPCPMPNFTLTFLAIGDRQIRLHLDIKKNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F725</accession>
    <name>A0A2G4F725_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anti-anti-sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000255</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57407">
        <property type="protein sequence ID" value="PHX57407"/>
        <property type="gene ID" value="CP500_000255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="52"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="332" mass="37150" checksum="D4F38BE8D8F0F899" modified="2018-01-31" version="1">MVSQTPEADFRVTYLDEIPSVHIPVRLSVLEAVNFKTTCQQLFSGSTVPSKIVLDFSQTTFIDSSGIGALVSNLKFAKQRDSDLVLRSLKPQVKAVFELTSLDQVLTIESSPVSTAPSENNRADSQLPVTHPSVRSLVKRLIDIVGAIVGLIITGILFIPIVAAITINDPGPIFFAQTRCGWMGKKFRIWKFRSMCTNAEALKSQIKNQASGAFFKNDNDPRITKVGRILRKTSLDELPQFWNVLKGEMSLVGTRPPTPDEVDRYEVPQWQRFDVKPGMTGEWQVNGRSQVRNFEDVISLDLKYQENWSLMYDLKLIVKTIAVLFNKNSGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUD7</accession>
    <name>A0A2G4EUD7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_023065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000262">
        <property type="protein sequence ID" value="PHX53151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53151">
        <property type="protein sequence ID" value="PHX53151"/>
        <property type="gene ID" value="CP500_023065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="185" mass="20348" checksum="6FF62C8A73A091D1" modified="2018-01-31" version="1">MAEPIKAVNATIQLSDTLTLDGYMMPDGEFRAGIAGASVLLGYAKNWFNRLRSEAPNKLKALQDGGLTGYVQPVVIQRESGARGASRAQTISLKDLATLITVEALQGNKRAIALQAAFTLEGLDSRFRDAFGVQQRTPEEKRCFFGLTYGEFLDALAENRAELEELRLPGDDLYYPEETDVDLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUR3</accession>
    <name>A0A2G4EUR3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tellurium resistance protein TerX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000224">
        <property type="protein sequence ID" value="PHX53279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53279">
        <property type="protein sequence ID" value="PHX53279"/>
        <property type="gene ID" value="CP500_022355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06974">
        <property type="entry name" value="TerD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003325">
        <property type="entry name" value="TerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02342">
        <property type="entry name" value="TerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TerD" evidence="1">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="199" mass="21946" checksum="B5005254B57209C2" modified="2018-01-31" version="1">MAINLTKGQSIVLSKSEYDLSRVTMALGWDVAKAKTGLFGRSSGANFDLDAYALLLGENGKLKNYKDDVIYYGHLESKDKTVVHTGDNLTGAGDGDDEQILVKLSALPEQYHKIILGVNIYDAKDRKQHFGLVDNAFVRAVDATGKEIARYRLSNDPSYEGKLNMLMGEVYREGGEWKFKALGNPLAEDMNGVVGSFMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUR4</accession>
    <name>A0A2G4EUR4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cysE</name>
        <name evidence="7" type="ORF">CP500_022630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000236">
        <property type="protein sequence ID" value="PHX53228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53228">
        <property type="protein sequence ID" value="PHX53228"/>
        <property type="gene ID" value="CP500_022630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="29049" checksum="40EE585E09F04241" modified="2018-01-31" version="1">MLKTLRADFSIIFDRDPAARNWLEVLFCYPGLQALVFHRIAHWLYLLGLPFIPRLISHMARFFTGIEIHPGATIGKSVFIDHGMGVVIGETAIIGDFALIYQGVTLGGTGKESGKRHPTIGENVVVGAGAKVLGNLQIGNNVRIGAGSVVLRDVPSDCTVVGIPGRIVYRSGVRVNPLEHGSLPDSEAVVIRSLVDRIESLEQQIKTLQTQQPISLTSDPNSHNFHLVSEALNQARNVAVAEKIQLAVANTCQLKDKAIQEFFDGSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUU5</accession>
    <name>A0A2G4EUU5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cell shape protein MreC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_022155</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MreC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000217">
        <property type="protein sequence ID" value="PHX53313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53313">
        <property type="protein sequence ID" value="PHX53313"/>
        <property type="gene ID" value="CP500_022155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042177">
        <property type="entry name" value="Cell/Rod_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042175">
        <property type="entry name" value="Cell/Rod_MreC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007221">
        <property type="entry name" value="MreC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34138">
        <property type="entry name" value="PTHR34138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04085">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00219">
        <property type="entry name" value="mreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="272" mass="29729" checksum="8C027D475613E92C" modified="2018-01-31" version="1">MLKNTFRRWWDLRLPITLLGLALTVAWGVRQTQGAAIFEAYNFVTRPFHANGSEQEQLILARTQELQAQVLELETQNQKLKELLNFVSANKIKGVVAPIIGRSADHWWQQVTLARGSNDGIKPDFTVMGTGGLVGRVVSVTPNTSLVLLISDHTSQLGVAVTRTRHMGFLRGKGKNQAVMEFFDNVPNVKPGDVVSTSSFSQLFPASLPVGKVVSVDMNKTPAPEAVIEFSAPINALEWAVVYPHSKDTSKEVEQKAADAQTSAPIGGVEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUW2</accession>
    <name>A0A2G4EUW2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_022140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000216">
        <property type="protein sequence ID" value="PHX53321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53321">
        <property type="protein sequence ID" value="PHX53321"/>
        <property type="gene ID" value="CP500_022140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheB-type methylesterase" evidence="6">
        <location>
            <begin position="31"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="CheR-type methyltransferase" evidence="7">
        <location>
            <begin position="244"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="1030"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="1280"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="678"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="1329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1401" mass="155325" checksum="458557A47F62EC3E" modified="2018-01-31" version="1">MTANQPDLENTPDSIALPAIDPAEQNTVEAPFPIVGIVASAGGLEAFRKLLGHLPADTGMAFVLIQHLAPDHKSLLTEILAKTTQMPVSQVTNGTTVEPNQVYIIPPNTKMTLVEGVLKLTPREKVYGKYMPGDAFLVSLAADRGHKSMAVVLSGGDGDGSLGIKAIKAAGGVTFAQCEASAKVDSMPNTAVATGDVDFVLPPQQIAEELANLSANPWISCQIPTIAVAELPELKDVRATILGLLRSTTGVDFTHYKVATIDRRIQRRMLLYKLDRLEDYAKYLREYPAEIQALYQEILIHVTSFFRDPEVFQRLKELVLPTITHNKSAKNPIRIWVAGCSTGEEVYSIAICLLEFLGDRAPLPQIQIFATNISEAAIHKARSGFYSENQMIDVSAERRTRFFILEGAGYRINKSVRELCIFARQNLGSDPPFSNLDLISCRNVLIYLAEPLQKRVIPIFHYSLNQTGFLLLGTSESIGKFSYLFNSVHTKCKIYARKLTENNPIFSFTTSSYPVARVDESEQINKNDPNTLDLQRYTDELILNRYAPPGVVVNEQMNILQVRGDTNAYLRLTPGIPSLNLMTMAREGLLIELRTAIYQALMQNVIVRKERVTVEPGEGESFVNIQVIPFQPATVEKNYFLILFEEVLPTAINLSTVSSESVETTDLEREIVWLRQALATANEEKKSVQANLQAVILDQENLNQDIKVANEEILSSNEELQSTNEELETAKEEIQATNEELTTTNEELRSRNFEQYEVNNDLINLLASINIPILILANDLQIRRFTPMAQQLFNLIPTDIGRPFSDIRSTLDVPDLSAMILEVIDTLHTKEQEVKTLDGYWYILRIRPYRTTENRIDGVVMVWIDIDALKRSAKTLELARNYAETIVETVQTPLVVLDADLQVNTANRSFYETFQVSSPETSHISLFELGNGQWNIPQLRSILEEILVSDVELHNFELDHVFEQIGQKTMLLNACKLQREDQGLMILLSIEDITDRRQFELDRSQLLQQEQSARQQAESSNRAKDEFLANLSHELRNPLTPILGWAKLLRSGKLNEAAVTRALDIIERSAIAQTQLIEDILDISRITSGKLNLDTSPIDLVVVAQSAIEGVQLSADAKNIQMLAQLSSATVLGDANRLQQVLWNLLSNSIKFTPSGGRVEIVLEAIDSHAQIRVSDTGKGILAEFLPYIFDRFHQGDSSTTKANQGLGLGLSIVRHLVELHGGTVQAESPGEGQGTTMTVRLPLVSIAQELTPPSNLEPTVFTSSVNASTDYIRSLEGLHILSVDDDADTRELLKFVLEDYGAEVETVGSAKEAIAALTENLYDVLISDIGMPGEDGYSLIQQVRSLDAAAGGNIPAIALTAYASDGERIKAIDIGFNKHIAKPVKPIQLALIVAELAGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUX0</accession>
    <name>A0A2G4EUX0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000228">
        <property type="protein sequence ID" value="PHX53256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53256">
        <property type="protein sequence ID" value="PHX53256"/>
        <property type="gene ID" value="CP500_022445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10347" checksum="44E5DCCDCC8DF546" modified="2018-01-31" version="1">MPIVTWQLWLARQLVAQCPLPWQKAQVKLTPGRVAQSFGSILAVLGTPARPPKLRGKSPGWLRGRKRRPRIRYPTVKKGFARPKKLNKKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV24</accession>
    <name>A0A2G4EV24_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_021800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000205">
        <property type="protein sequence ID" value="PHX53384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53384">
        <property type="protein sequence ID" value="PHX53384"/>
        <property type="gene ID" value="CP500_021800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="402"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="650" mass="69603" checksum="617244A9A8E50DBB" modified="2018-01-31" version="1">METPFNITLLMVMTVTCGISAQVLAAYLKVPAIVFLLLFGILSGPDCLGLLHPNLLGSGLEVMVSLSVALILFEGGLNLELRDLGRVSGSIRNLVTFGTLITLIGGGMAAHWLGEFPWPIAFLYASLVVVTGPTVIGPLLKQVSVDKQVAALLEAEGVLIDPVGAILAVLVLNIILNGNADLLVLFRDLIVRLGVGAFVGVAGGWLLGFILKRSQFLSEDLKNLVVLAGLWGLFGLAEELRSESGLMATVLSGIVLRSASVPEERLLRRFKGQLTVLAISVLFVLLAADLSLASVVALGWGSVFTVLALMWIVRPINIWLCTWNSGLNWQQKLFACWVAPRGIVSASIASLFAILLTQRGINGGDSIKALVFLTIIMTVFVQGLTAGPVAQLLGVTSKSATGAVIVGSNPLSRLMARLFQERGESVAIIDTNPEACQAAEQEGLRVFLSSALDHSILEAAGLASMGTFLAMTNNGEVNLVLAQRAAEEFAPPRVLAMFPKDPQGNSAANNSKINQAFVSDLSLKDWNEYLIDKEVKLGETELKSLGLEFQLAHLQALVRSGELVPLMLERQGYLQVVSAGEIWQAGDKIIYLLHDPTPKLLKRLSGSSQSRLTLEKHPVVEEVPIPTPVLDDVLEEAITEVIEDTAIEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV44</accession>
    <name>A0A2G4EV44_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53404">
        <property type="protein sequence ID" value="PHX53404"/>
        <property type="gene ID" value="CP500_021670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="9952" checksum="57904AF41F417F56" modified="2018-01-31" version="1">MAKSQKTNRDHAKKNTRPMVEDEAIASQLSALLTPAITSQENYYCQLGLRGIIFNLPLRNSWKERVFWAIAIIDINLLTKVDSLFSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV65</accession>
    <name>A0A2G4EV65_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000198">
        <property type="protein sequence ID" value="PHX53429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53429">
        <property type="protein sequence ID" value="PHX53429"/>
        <property type="gene ID" value="CP500_021535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="203"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="420" mass="48061" checksum="3C079A5DDA9B1F34" modified="2018-01-31" version="1">MRTNNNLTILQPLQAKLLPNDKVLLTRKLIEAVEEFKNYWDGSITVMMEETQVDNGNIDQKVFNINELPFTLEVISFDQITPDLLNKHKSSLVLAVPEHRQNHISKVCQLAGVPCIYVSEYSLKTRKQIVNVSTNNPLVRLRRIIWTYRQEMRQRQAIAIADGLQCNGTPTYEEYKNLNRNPLFFFDTRISADMLATEADIEMRTKNRSQDDPLRLVFSGRLIKMKGADHLIEVAKELKKMKVKFEMFISGAGDLEETMYKQIASNQLNDWVKMLGVPDFKTEFFPFVKKHIDLFVCCHRQGDPSCTYIETMSCGVPIVGYANEAFEGIAGMSEAGWVVPMNQPKLMAKKIAELSQNREAIKSMSFKSLNFAQQNTFERTFKARIEHMQQVIAKSIGVHQAPESELSDEKSPVFGYCQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVA4</accession>
    <name>A0A2G4EVA4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_021385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000194">
        <property type="protein sequence ID" value="PHX53464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53464">
        <property type="protein sequence ID" value="PHX53464"/>
        <property type="gene ID" value="CP500_021385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02414">
        <property type="entry name" value="jag_KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02644">
        <property type="entry name" value="R3H_jag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038008">
        <property type="entry name" value="Jag_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039247">
        <property type="entry name" value="KhpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034079">
        <property type="entry name" value="R3H_KhpB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35800">
        <property type="entry name" value="PTHR35800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="SSF82708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="3">
        <location>
            <begin position="92"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="157" mass="18010" checksum="EF88FFEE7015A277" modified="2018-01-31" version="1">MKDSQMQRGQQWLEEFLTLSAIPSKVVCEQQADCYWMTIDDSNLTPEQIAILVGPNGDSLDAIQYICNTVLNIGNEVEEPTAYTVELNGYRIRRQEELRSMAEYSAQQARMTGVEVELKSLSSSERRQVHSFLSESEDIETYSQGQEPDRRLVVRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVD7</accession>
    <name>A0A2G4EVD7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_023135</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000268">
        <property type="protein sequence ID" value="PHX53137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53137">
        <property type="protein sequence ID" value="PHX53137"/>
        <property type="gene ID" value="CP500_023135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 2 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="6">
        <location>
            <begin position="194"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="309" mass="33153" checksum="DC52D7E2B001759F" modified="2018-01-31" version="1">MTASFNQKPAIPPTRVPKSRGKGVFLLSLIFRLLLLGVGSGFAWVLGMTIAQIYPSTATQMPLAERLLRLTQNSTPATKRTPVTPIPLLQTPKTTPSPQSQINPAVKQKLQSDLRQLQGELNALIGRTAALESQLGSSRPTETLEKRLQLMSRELASPETTTTPTPALPAIGGTPTPQPATTAPQSENNPVFAGDALMVTLPSDVLFDTGSISLRAGTNAILDNLVADLRNYEGATVRVAGHTDNVGEVADNRNLSFARAQAVANYLSNVLGQKYHWVAIGYGESRPSVDNGSDANRQRNRRIEVAISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVF8</accession>
    <name>A0A2G4EVF8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpmH</name>
        <name evidence="5" type="synonym">rpl34</name>
        <name evidence="7" type="ORF">CP500_021365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000194">
        <property type="protein sequence ID" value="PHX53458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006632320.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53458">
        <property type="protein sequence ID" value="PHX53458"/>
        <property type="gene ID" value="CP500_021365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="45" mass="5220" checksum="5229F6AA6373409B" modified="2018-01-31" version="1">MTQQTLHGTSRKRKRTSGFRARMRTATGRLVIKARRSKGRHRLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWD5</accession>
    <name>A0A2G4EWD5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_019290</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000149">
        <property type="protein sequence ID" value="PHX53844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53844">
        <property type="protein sequence ID" value="PHX53844"/>
        <property type="gene ID" value="CP500_019290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="12">
        <location>
            <begin position="23"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX53844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="261" mass="29464" checksum="229D5CA3AB4716B1" modified="2018-01-31" version="1">MLTRSQIGFYLEDIETPIGRTVNLTLTGLILLSSASFIAETYPLAEPVRINLQTLDTVLLIVFAFEYLLRLWCAENKVKFIFSFFSVIDLVAILPFFLGFVNVSFIRIFRWFRILRLIRFLELKISIFRISTEDGVIFARILFTLLAIIFVYSGLIYQVEHPANPEGFGTFLDAVYFSVVTMTTVGFGDVTPISETGRFLTILMILTGIALIPWQLGDLIKQLVKTANQVETVCTGCGWSVHDTNARFCKMCGTHLDNGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWI7</accession>
    <name>A0A2G4EWI7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Photosystem II reaction center protein I</fullName>
            <shortName evidence="8">PSII-I</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PSII 4.4 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">psbI</name>
        <name evidence="9" type="ORF">CP500_019395</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cellular thylakoid membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PsbI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000151">
        <property type="protein sequence ID" value="PHX53826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53826">
        <property type="protein sequence ID" value="PHX53826"/>
        <property type="gene ID" value="CP500_019395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01316">
        <property type="entry name" value="PSII_PsbI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003686">
        <property type="entry name" value="PSII_PsbI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037271">
        <property type="entry name" value="PSII_PsbI_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35772">
        <property type="entry name" value="PTHR35772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02532">
        <property type="entry name" value="PsbI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161041">
        <property type="entry name" value="SSF161041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="2 8" id="KW-0674">Reaction center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="46" mass="5286" checksum="F0C08A650736A75E" modified="2018-01-31" version="1">MAFLETPTVLTLKIVVNVIVLFFVSLFIFGFLSNDPARNPNRRDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWL9</accession>
    <name>A0A2G4EWL9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_018775</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000137">
        <property type="protein sequence ID" value="PHX53952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53952">
        <property type="protein sequence ID" value="PHX53952"/>
        <property type="gene ID" value="CP500_018775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="PTHR10887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_11" evidence="2">
        <location>
            <begin position="361"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_11" evidence="2">
        <location>
            <begin position="984"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_12" evidence="3">
        <location>
            <begin position="1197"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="656"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1023"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1434" mass="162366" checksum="2D26C071480D99B4" modified="2018-01-31" version="1">MPSLVAEDWGYKFTSNRAINKFIRDVEGEAALAKYCDWESKERAEVLMSEIVSKSHNLFYVRRQQVNQRFAEEEIWELIIATDEDEFELPELLQKADRTLRLLACVRFEDGIGGLKLLDAGLVHRLRGNKDGYVLPQKLRLLGNSKAGIPRKSIANVQQLPFWDDRHIPTTEQLKVWHTFLKVEKRIAEARQFCVPFRGHNYGSSLKIITLEIDCSSATLDGYDENPLELGDFRERLKKARNEEITLFDSAPGSRSNRDGDRLGSIAEVDFEHSKLRIKLDPDLASRMAGDRYFLPKQGFLYFEAAGDISQIKRKEQALKMLTDGRSQNPYLSDFLFDATQARLPKKSIKLDRENLLNRNANADQIAAVETVLSARDLILIQGPPGTGKTTVIAEICYQIARLGGKTLIASQANLAVDNALSRLVHNPAIRALRKGKAHKVQEEGQPFLEENAIGTWLQNTAIDCEQKLLQRQTNVTYLRHLLAESERFAAYFTAESEFHNQQKHLYSSKASLEANCNYQETAYQASLAQKEEIESLFLGLESLLAAPQIDWESSEITEFLPRLKPFSEGNILVENFLANVRIAANNATQIGFSRPACGAFGIAVWLRETVAPQISEFKTAFDCADDACHAMSGVGESLLVSRQISDALSQLQLGDRQNQTNRHNLEQKIQNLELRKAEIATVVVAVAEWIQTADTQLYEVVKSCLETGALLTDEMVELPVGLLKIARSLKLPIVPPKWKVSLPDLERLQKAISHEANAGFKDIQGQQFRFSEFLHLNLSQTPIVLSVGDRTQWQQLAKDFDNYSKATPSQRKFIIEKAHTLLSNIQQIYSASLQPNNIQNTLERLAKELLHSILGNARQCMVPLKTETEQQLQKQQQLLDRLNSSLNQPEISALQHQVATAQQATNLKINEVTNLLQAIVQQPNVPEKLRTLAEQYIAQKSNIWEQPQQFIRQVDTWKASAVQLESSISDLDTFGILTIIKDSLNEHLSPLKLASEKSLQQLEELQKELSEIMAQIEQQQPTPELIVDRNWWESAWQNIPDKSKAEVSSTGLFAIDFLRKIKRQFKTWQRELEADETELNRSQNFVTDWIEKLRNPSEKDQTDLKQIYIDNANVIGITCVQAASFDFSKNFPSFDAVIIDEVSKCTPPELLIPALKGKKLVLVGDHRQLPPMFDRNTIDDIAEEIGCTGDELSFIKESLFKTLFENANDSIKQMLTTQYRMHPQIMGAINQFYEQKLNCGIAEPDEKRAHNLPGKIIQENNHILWVKTPIGQGFEEERNGTSRLNVKEVDAIERLCQQMERAWYPKVANGEPPKEIGIITFYGAQLRLIQDTIEAEKFPSLSIRTGTVDIFQGMERPVIIVSTVCNNNRGDIGFAKEPERVNVAFSRAQELLVVVGCHDLFTQQTGTVGKMYQEVSKIVRYFGGFVDVSSVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWM1</accession>
    <name>A0A2G4EWM1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53921">
        <property type="protein sequence ID" value="PHX53921"/>
        <property type="gene ID" value="CP500_018865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013612820" evidence="2">
        <location>
            <begin position="28"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="12420" checksum="2719557D7D8BB3A3" modified="2018-01-31" version="1">MKHSNLLLLSVAFLLLSGMVTTPAARAKPSDIASETKVPVSPMPRESSDRFSMPATFAQPNAQSNDRPLCFYQRSDSTIVDLSKLCGAKSTETGTNTRWENAPAEEKNTPIYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWS0</accession>
    <name>A0A2G4EWS0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptide chain release factor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000135">
        <property type="protein sequence ID" value="PHX53971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53971">
        <property type="protein sequence ID" value="PHX53971"/>
        <property type="gene ID" value="CP500_018670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="128" mass="14191" checksum="9EAD78E7A994B036" modified="2018-01-31" version="1">MQIPSTPSYFQGFSLLLTTRNDLSSIRSNIRRLKPKTLDLAGIPAATNSSAISDQNVNKVETAADLFHKPTGIRIFCTEERSQLMLTNFFLLPSSFKLLPSNYLSHNLIVWSLEPLAIVLPSGLKVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWX2</accession>
    <name>A0A2G4EWX2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipid kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000138">
        <property type="protein sequence ID" value="PHX53940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53940">
        <property type="protein sequence ID" value="PHX53940"/>
        <property type="gene ID" value="CP500_018780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005218">
        <property type="entry name" value="Diacylglycerol/lipid_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00147">
        <property type="entry name" value="TIGR00147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="319" mass="33496" checksum="424FB36E6C46793F" modified="2018-01-31" version="1">MKRSACLIFNPAAGQSNPEQDLALIRQLLEPTIDLEIRLTTPELDGAEIALEAVSRGVESIIASGGDGTLSAVAGAIVGTNIPLGIVSRGTANAFANALDLPNTIETACETILGGLTRVVDAGICNGKLPMVLLAGVGFEAETVEMTDREMKNRWGMLAYVLSGIKQLNNLERFEAEIETEDKIVTVTAVAVTVANAAPPTSILAQGPAGIIFDDGLLDITLVAPENKAGAIAASYHLLQTALTGNASDRDDIGYMRAKKIKISTDPPQKVVLDGEIIGMTPLFIECVPGGLTVFVPRVEEPPVTEKLTGLSDIKVVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWZ1</accession>
    <name>A0A2G4EWZ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53960">
        <property type="protein sequence ID" value="PHX53960"/>
        <property type="gene ID" value="CP500_018720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="450" mass="52175" checksum="68FE488F2F692FAA" modified="2018-01-31" version="1">MHLLRVQVPDFRGLKDIDITFEKDFFPKIFPLGSQNGGGKSTLLQLIFILLHCSVDEDKQEFLQNLLQGFKVYDGEEKRVLAIIDIWDGEKVVEIEFFCYKDSFFKELLTSDSKEETIHEAHLSFSILAKLKLLQNNISVLEVENSFIENKQFNSVFTRNEQVIAKFYQECRQIEARCQNVIEYLESKNMTYICNYSSNRNLHDKQDEALLYHFNNLDIDMKKANYFLWELSYKIFLAAPSTQIFLFLAPASRKLLFGNSSNGDNNYYAILESARSELNGLFTYDFLAVELLIESFKAARDRDFKEAIKTGDYGNSYQALINELNLLVGNKRINVNEDLAGVNFKLDNNGETIELYPEDLSHGELKRLSIYIWLKSRNIEDAIVLMDEVEIAFHPDWQYQIISDLQEWAPSNQYILATHSYALCEALTPAHVKEIEPKLIKQESNITNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX05</accession>
    <name>A0A2G4EX05_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000128">
        <property type="protein sequence ID" value="PHX54063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54063">
        <property type="protein sequence ID" value="PHX54063"/>
        <property type="gene ID" value="CP500_018150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="29"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="224" mass="24965" checksum="766A84B9984BFF61" modified="2018-01-31" version="1">MKQQSSASKQPKPVLENIFAFPPNRDTLGATAYFIVENQTNILVDCPAWDEINQTFLREHGGVRLLFLTHRGAIGKAREIQEATGCDILIQEQEAYLLPGLKVTAFEREFALSDRTLAFWTPGHSPGSSCLYDTRSGGVLFSGRHLLPNRDSAPEPYRTAKTFHWPRQINSVKSIVDRFSPETLQYICPGANTGFLRGKSAIDRAFEQLASLDLAVCLQSKPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX69</accession>
    <name>A0A2G4EX69_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3318 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53747">
        <property type="protein sequence ID" value="PHX53747"/>
        <property type="gene ID" value="CP500_019735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021751">
        <property type="entry name" value="DUF3318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11780">
        <property type="entry name" value="DUF3318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="22168" checksum="4B4E476283E11945" modified="2018-01-31" version="1">MNPEPEIRRLLDMMPASGRMMCKIINKPQQSKVIDSQFPLPWNRNRPIYINFDLWRLLSKPQRDLLILRSVSFLANVKWFKPDIYQGVALAGIVGTVVELLQGDAIGTAIAGGLTGLAMTRIWRDNRSSQVELDADEGAIKVALRRGYSESEAAKHLLGAIEAVAQIEGSGLDFNTLIRCQNLKAIAGISAVGVPDSIRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX73</accession>
    <name>A0A2G4EX73_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eno</name>
        <name evidence="13" type="ORF">CP500_018265</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000130">
        <property type="protein sequence ID" value="PHX54040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54040">
        <property type="protein sequence ID" value="PHX54040"/>
        <property type="gene ID" value="CP500_018265"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="9"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="144"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="367"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX54040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="429" mass="45938" checksum="9F24F99DF77E4AFF" modified="2018-01-31" version="1">MVNMLDTAIESIQAREILDSRGRPTIEAEVYLASGVVGLAQVPSGASTGSFEAHELRDDDKKRYGGKGVLKAVDNVQHKIAPALIDLDAIDQALIDRTMIDLDGSPNKSNLGANAILGVSLATAKAAAETLGLPLYRYLGGTLANVLPVPLMNVINGGSHADNNVDIQEFMIVPVGAPSFKEALRWGAEVFASLAKVLKDKNLLTGVGDEGGFAPNLGSNQEALDLLMMAIEKAGYKPGEQVALALDVAASEFYKDGQYTYDGVAHSPAELIDYLDGLVSQYPIVSIEDGLHEDDWDSWVALTEKLGSKIQLVGDDLFVTNRTRLQKGIDLKASNSILIKLNQIGSLTETLDTIDLGKRNSYRSVISHRSGETEDTTIADLAVATRAGQIKTGSLCRSERVAKYNRLLRIEAQLGDRAIYAGAIGYGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXA7</accession>
    <name>A0A2G4EXA7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000118">
        <property type="protein sequence ID" value="PHX54174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54174">
        <property type="protein sequence ID" value="PHX54174"/>
        <property type="gene ID" value="CP500_017535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="381" mass="43583" checksum="34AB83900FC93290" modified="2018-01-31" version="1">MAGGIYLIQDDDRLLEMMEQPYDSEDQLQDLLVTYPNLIAGDQIDRATARKWLLISREFATPIDEETAVQWSLDHLFIDQNAVPTLVDVRRTPNAALRQKVLGQSIDYAANAVVYWPIDSIIAFFEANCRDRGRDPEQIFEEFLGPDANEDRFWQKVKTNLQAGKIRLVFVGEEISAEMRRVVEFLNEQMDPVEVFALEIKQYVSEDGLRTLVPTVIGQTAEAQQKKSSTTRERRRWDESSFFAELKARRGAEEAQMAKEIYVWAKTQEPEVQINWGTGDIYGGFAVQLSQNGRKPYQLFTVDIAGRMEISAHNYGSQPPFSSEENWLELRNKLSSIGLSLPTEPGERRSPSLALFTLQDESAKKQVMETFDWVIEQIKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXC5</accession>
    <name>A0A2G4EXC5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54126">
        <property type="protein sequence ID" value="PHX54126"/>
        <property type="gene ID" value="CP500_017845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="222" mass="25101" checksum="FF7C27D31F5D99AD" modified="2018-01-31" version="1">MRINLPQFPEKERLNDHIGEIIETATTEFLAQCLDPEDLSFPPMPPFGSWVKATDEQSGNLVIAVVYHATTSPIDTVHRARALGMSLQELREEQPQIFAMLKTEFRSAIVGFETAAESLNGYAPQRGTIYQYIPPRPPQIHQAVYRCEPDEVIDFSAQLDFLRTLLGVANAPVDALTAAAIREVYQLRKRDRSWLVEAGRSLSVLLKDDYDRLRVILSQIHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXD3</accession>
    <name>A0A2G4EXD3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000121">
        <property type="protein sequence ID" value="PHX54138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54138">
        <property type="protein sequence ID" value="PHX54138"/>
        <property type="gene ID" value="CP500_017720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="245"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="312" mass="35716" checksum="D11E5DD4CF4617BF" modified="2018-01-31" version="1">MTFINPKTDFAFKKIFGSENSKDILISFLNALLYDGQPTIQSLRIYPPYSAPRIRGLKETYLDIKAELDDDTTVIIEMQVLNVEAFEKRILYNAAKAYSTQLETADKYALLNPVIALTITDFEMFEDFTKVTSRFVLKEKDFLIDYPVYDIELVFVELPKFKKTLNELETLTDKWIYFLKTAKDLSVVPETMQSVPEIQKAFTIANRCALTREELTDLENEEIYIQDRRGAISKAVKQGREEGRQEGVKAGQLALIIRLLERRVGAVDSEVESQIQQLPIALLENLADELLNFNDISDLTAWLQTNDLSSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXE9</accession>
    <name>A0A2G4EXE9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54201">
        <property type="protein sequence ID" value="PHX54201"/>
        <property type="gene ID" value="CP500_017470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="10187" checksum="0897F1A74CDCE90D" modified="2018-01-31" version="1">MIKDEDRQTHGANKSVLEQINSLKREDERLYNILAIDVWALAKTMDEYQPGFWAAFMKNREKALKRFLAEMIKNKSTDSKRPPFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXF2</accession>
    <name>A0A2G4EXF2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PEP-CTERM sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_017815</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54120">
        <property type="protein sequence ID" value="PHX54120"/>
        <property type="gene ID" value="CP500_017815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014270">
        <property type="entry name" value="PEP-CTERM_IMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02921">
        <property type="entry name" value="PEP_integral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="933"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="416"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="898"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="898"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="958" mass="107372" checksum="E7777412B4334D40" modified="2018-01-31" version="1">MKRFKLALNIIFQSIFWLWNLTFLSIVYLGILPYVGIPLIQATIDGTIPLEFALTLTAMVAVPTVSTIIGARYLRKQPLQLMRLFYGVEAPLFLLCLIRLFLLRQLTPASSQIIATIALCIGAFLVEILYGYLGKTENTESELVWKKFHEKQFFLTSLIGHKNSASIQLAFHSLMLVVGTWAATLLMFYALPVAIVTIVGFFSFAWVQPLVESLKYSSLSIIWWLPLSLIMFGFTSSLFVVMPSLYGFLYIQSGRKIFRSFASQYGKSQAIIGSLGVIAAWIAIFATLQQQPQIQALKMLATPPKDESSRQTLLAKSDIVRSGLVNAYLHPYRYLSTVEENNHISEIYKNTLNLNEAAAKAVQNSYNFLMSPFLYQGSDADIKKAEKLYGEFFDTELQKGDREAVQYAVQSTSNREEAKAGLLNVNQEKVWLESQAVTVTENGDWADVQLYEVYKNQTPNLQEVFYYFSLPESAAVTGIWLGDTGDLKKRFAFTVSPRGAAQQVYNQQVRENVDPALLEQIGPKQYRLRAFPIPAKREFRQTEGPTEMHLWLTYKVMRQAQGWAMPNLAEKRNIFWDKNTRRTIAGKQVKYSGKEAKEIWLPAFVPAVAPPQIIPRIAILPGGNTISAKPLVDANYLSPQGKKFAFVLDTSRSMATETKEMKDNFEWLKNNVLAANTVDLYVASAVGIPPKLVKDLRSFDVGKLTFYGTLQLKDILQQFAQLRGDRTYDSVFVVSDRHSYELSDDRKNAISMPSPLWTVHLGGLPPGYDDATLKVIQDSGGGVATDIKEAMQRVATTAASGDSIVSVVDGYAWSYTKKPKSEKAVQSVAATELRDDKNEGFKPIAARQLIMALSKEKSSNQLSQLDAMHSVAKTFNVVTPYSSMIVLVNDAQRQQLKEAESKKDRFERKVESGKEELTKPGNPLNVSGVPEPAEWLLLGFGAIGLLAIFLRQRREKMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXT3</accession>
    <name>A0A2G4EXT3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54331">
        <property type="protein sequence ID" value="PHX54331"/>
        <property type="gene ID" value="CP500_016790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7064" checksum="CAAC1DC37D2CE391" modified="2018-01-31" version="1">MVLDFLMPIAFIWMPQLYIWMLGIFCRSAQLKTYNGEFGPQSGTKITFAYLGAASIKLCPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXT4</accession>
    <name>A0A2G4EXT4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase sigma factor, RpoD/SigA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_017100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54260">
        <property type="protein sequence ID" value="PHX54260"/>
        <property type="gene ID" value="CP500_017100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017848">
        <property type="entry name" value="RNA_pol_sigma_RpoD_cyanobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02997">
        <property type="entry name" value="Sig70-cyanoRpoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="5">
        <location>
            <begin position="317"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="357" mass="41189" checksum="B1E33F75F1FEDD5D" modified="2018-01-31" version="1">MAESDLGSFAVAPEASLAIAEDEDIEIDRPISTRSSAYNNWSADDPVGALFKEMARYPLLTASEEVELARRIRELVALEELEKGLKQELGRVPTKAELAEAMGLSETQLQSLRHQCQSAKRKMISSNLRLVVSIAKRYLNRGVPFLDLIQEGALGLNRATEKFDPEKGYKFSTYAYWWIRQGITRTIANQGRTIRLPVHIVEQLNKLKRVYRDLRRSLQRNPTEAELAKDMEVTSEQLRYLQQVRRQSLSLNHRIGSEETSELLDVLEDHSTQSPESQMNEMMMRQDILEVLDNILTEREKEIVAMRYGLVTGEPYTLEEVSTLFNLSRERVRQIQNKAMRKLRRPQVTERLKGWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXT8</accession>
    <name>A0A2G4EXT8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54339">
        <property type="protein sequence ID" value="PHX54339"/>
        <property type="gene ID" value="CP500_016630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="256"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="435" mass="49650" checksum="DB0151F4A28592A5" modified="2018-01-31" version="1">MNQPIIRFLTTKNYKNLQLYPSVNLNNLNIFIGSNGSGKSNFISCLKFLKDCLTSIPDENRGVSSFEDAIYKFGGDKILDVNVESPAKVSIAYCFSQINQTGNLQKDSAILDFKLYIDRQKVRASLSEEYLYGGEDLQETCSRQPFYYYKFHNRELGQGVLSVYNFPGQEPTHFETLDNIPTNSLGLLTIPTLLENSQSPPENTPIYKIRRELIEFISKWQFYNANNMNLSLIRTVEPKIGGSDIYLSASGDNLPLVLYNLNQKSLNFEDSINEAMKSILPKTRRLRALPSGRLSLTVQWFFEGIDDEAFYLNEMSDGTVRMLCWATILHSPLLPSLIVIDEPELGLHVSWMPVLAEWIKKAARKTQIIITTHSPDLLDHFTDCLENVLCFYSENRTHFSVKSLSKEMLDQKLEEGWELGDLYRVGDPSIGGWPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXW3</accession>
    <name>A0A2G4EXW3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-galactopyranose mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54361">
        <property type="protein sequence ID" value="PHX54361"/>
        <property type="gene ID" value="CP500_016535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="325"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="650" mass="72260" checksum="9504346A04B1EE21" modified="2018-01-31" version="1">MSQSTNSPLPQTVSRRTALKFLGVGAAGGLLGYSRFSKPEPTIFVQETLDLPRLLNKPKTVIVVGAGLAGLACAYELSQRGFAVTLLEKSPQLGGKIASWPIQVGNQTFMMEHGFHGFFPQYYNLKSVVQELEITDNFVSLESYAVIFRDGKYKPEVFRPNHSAFPWNIVDLGIASPNWTKWGINLTKPAHWQVFREIGGFQTQKSFARLDNISVADWVKGEFPRGLYDLYFMPFAKSSLNSPDELSVGELMQFFHFYFFGNPEGLAFNGTRQDMGTSLVQPIAKSIEKKGGKVLTDVAVSGIHWENGKINSLSYQSGDVQTKIPFWVKHNSLLNDSNSTEYFGAGDSVYATVPGGQEAISLSCTHQGCTVQKQNDGQFHCPCHGAVFDAEGRVVSGPAQRDLPRFKVVAKKADEVQLAAAIDNSQPQKLGETLQADYYVLAADVPGMQHLFSLASGEVNPQVQSRIEGLKIADPFAVGRFWFDRDFAWKHSNFSSLSGYKLTDSITLYHRIQEQFIAWNKETGGSVVELHAYCYKEKEFPNQEVLLATFEQELYEIVPELKEANMLHRELVNQKNFSGYPPGSYAERPETCCDVPNLLFAGDWVKMPFPCGLMERAVSSGLLAANAILHQEGLQRRSLLTVNPEGVLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY22</accession>
    <name>A0A2G4EY22_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000101">
        <property type="protein sequence ID" value="PHX54434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54434">
        <property type="protein sequence ID" value="PHX54434"/>
        <property type="gene ID" value="CP500_016110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="11294" checksum="74FC21DB396E87C8" modified="2018-01-31" version="1">MPVPQRLYFLVAQASLPRTGRMPVPQRLYFLVAQASLPRTGRMPVPQRLYFLVAQASLPRTGRMPVPQKLYFLVKQAGKPVHQGLIENSTRSQFKPMVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY70</accession>
    <name>A0A2G4EY70_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mnmG</name>
        <name evidence="11" type="synonym">gidA</name>
        <name evidence="14" type="ORF">CP500_015910</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MnmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54469">
        <property type="protein sequence ID" value="PHX54469"/>
        <property type="gene ID" value="CP500_015910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="12">
        <location>
            <begin position="14"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA_C" evidence="13">
        <location>
            <begin position="409"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="19"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX54469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="638" mass="71404" checksum="36D753B0456D6743" modified="2018-01-31" version="1">MTAQTPVQFQDSFDIIVVGAGHSGCEAALATSRLGCRTLLLTLNLDKIAWQPCNPAVGGPAKTQLTNEVDALGGEIGKMADRTYLQKRILNSSRGPAVWALRAQTDKREYAAVMNNIVENQENLTIREAMVTDLVLGKNEEVIGVETYFGVAFECKAVILTTGTFLGGTIWVGNKSMPAGRAGEFAAVGLTETLNHLGFETGRLKTGTPARVDKRTLDYTNLEPQPGDADVRWFSFDPEVWIEREQMPCYLTRTTPETHQLIRDNLHLSPVYGGWVDAKGPRYCPSIEDKIVRFADKESHQIFIEPEGRDIPELYIQGFSTGLPETLQLQMLRTLPGLEKCEMMRPAYAVEYDYLPATQCFPTLMTKKIEGLFCAGQVNGTTGYEEAAAQGIVAGINAARFAKNQEMIVFPREQSYIGTLIDDLCTKDLREPYRMLTSRSEYRLLLRSDNADQRLTPLGREIGLIGDRRWELFEQKQANIVAEKKRLYSTRVKEHEDLGKQIFAETQQSINGSITLADLLRRPGFHYVDLERYNLGDSSLKLAEKDGAEIDIKYSGYLQKQQNQIDEIVRHERRQLPGDLDYMAITTLSKESREKLTKLRPLTIGQASRIGGVNPADVNALLIFLEVRNRQQPAGVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY79</accession>
    <name>A0A2G4EY79_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54495">
        <property type="protein sequence ID" value="PHX54495"/>
        <property type="gene ID" value="CP500_015775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13518" checksum="D07549886EEBBF05" modified="2018-01-31" version="1">MPEVNQIYLTKQHHSRLTGKMPVPQSVSFVVQHHSRLTGKMPVPQSVSFVVQHHSRLTGKMPVPQSVSFVVQHHSRLTGKMPVPQSVSFVVGWASCPPIKGLNSQYFGLIKNAQDLHPGGTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY92</accession>
    <name>A0A2G4EY92_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3082 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54456">
        <property type="protein sequence ID" value="PHX54456"/>
        <property type="gene ID" value="CP500_015990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021434">
        <property type="entry name" value="DUF3082"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11282">
        <property type="entry name" value="DUF3082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="117" mass="11907" checksum="DEFC7611E8B560F1" modified="2018-01-31" version="1">MADLTNPNSTSQTPNSAENSSPTSPQPPTVLRCVTGSLMAGGFAAALYALTLSIAQTFANKPIHSDNLTVINIGAAVRTLVMGIVALGGGVFAFAAVGLMALALQLLIQKLVNKPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYC8</accession>
    <name>A0A2G4EYC8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54533">
        <property type="protein sequence ID" value="PHX54533"/>
        <property type="gene ID" value="CP500_015545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="224" mass="24883" checksum="02ED6B6E09A77167" modified="2018-01-31" version="1">MQPEQEQEILNLRDRQLTPKQIARKLGLKASEVSTFLISQAEQTALASAEKGELLPVAQCLVDVNFANVLLRNETSEAGGLGLVMVTRSKGYNRFVAATYLIDYWCLGVKDSIPPRNCNDSQYKTLIENSYSPFLGYEEISVEQAQALVWGAIAYSKILGFEPHRDFEQSKAHLGESTSEIGLKFGRNGKPFYVEGPYDNTTKIINTLKKSVGDGNFDYLFGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYD4</accession>
    <name>A0A2G4EYD4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mitomycin antibiotics/polyketide fumonisin biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54542">
        <property type="protein sequence ID" value="PHX54542"/>
        <property type="gene ID" value="CP500_015590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="316" mass="35856" checksum="BA7ED8C3A5AFEA0B" modified="2018-01-31" version="1">MTEETVTLRKSLDLDKLISLLPQAEDINYWRNLNSNSTISDRPFQGFSEFSGIPQAEIDEYALQLREEGYFQTPSVIPAATIHQMRDCIENVRKAGFPTMFALVYDIFYQAFGYFNSTLTGILGNSYKLVPNFWVYYIETSDSGKGFEPHRDAEYENTIDSNGMPTVLTIWVTITEANPLNSCMYLLPANRDPEYTEAIKNLNTKATKFALEDIRALPTQAGTLSCWDQYVFHWGSRSSSRAKSPRISYAVYCQRGDIPPVDDVIVDIPSVLDFSTRLSLICRGLYRYSYASLQPSPEAEALLDFLNKHTATLNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYX1</accession>
    <name>A0A2G4EYX1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="14">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="14">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pheT</name>
        <name evidence="19" type="ORF">CP500_014595</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="14"/>
    <dbReference type="EMBL" id="NXIB02000082">
        <property type="protein sequence ID" value="PHX54709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54709">
        <property type="protein sequence ID" value="PHX54709"/>
        <property type="gene ID" value="CP500_014595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="16">
        <location>
            <begin position="39"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="B5" evidence="18">
        <location>
            <begin position="412"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="17">
        <location>
            <begin position="721"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PHX54709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="815" mass="88857" checksum="1E58316D59DBEE2A" modified="2018-01-31" version="1">MRISLNWLRELVDVAIAPEELAETLTMAGFEVEEIEDRRPWADGVLLGKIVAIEQHPNADKLRVCQVDVGKPEPLNIVCGAPNARADIYVPVAVVGTFLSQIDLKIKPAKLRGVPSEGMICSLAELGLSKESAGIHIFELENPELGSDVRPLLGLDDVILDLTATANRADALSMVGVAREVAALTGGSLRIPEPADVAIQGENSPNLTVEIFESEGCPIYTGTTIEGVKIAPSPAWLQQRLQAAGVRPINNVVDVTNYILLEWGQPLHAFDRDRLQSFTATQDINIGVRFAKTGESFKTLDGQNRNLQPQNLLITASDKPVALAGVMGGESTEVHEGTQNLVLEAAIFDQATIRRSARAQGLRSESSIRYERGVNQAALTTACNRAVALILELAGGAATVQKTASSGADDLSFSRSLELRLDRVNLVLGKLKRGETGGSEYLEPEEVKHILTALGCEVVPAGKERVFAIAVPPYRYRDLEREIDLIEEIARLHGYDNFCETLPSKTEPGYLSPEYAAIRNVRSAFRAAGLTELMHYSLVKTEGDNQVVLANPLFVEYSALRTEMLSGLIDAFGYNLEQGNGALNGFEVGRIFWKEGDAMKEADAVAGIIGGDPTVWKWQQSGRDRPLTWFEAKGILESVFQQLGLAVEYQSDSSNSRLHPGRTAALWLNGKHLGIFGQLHPQLQQEKDLPEQVYVFQLDLAVLLAELGLTQNSTRKFAAYSSFPASDRDIAFFAPIKVAVAEMAGAMKKAAGSLLDSVELFDEYRGDNVPAGQRSLAFRLIYRSGDRTLSETDVEPAQQKVRDVLVEKFGVSLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ98</accession>
    <name>A0A2G4EZ98_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54830">
        <property type="protein sequence ID" value="PHX54830"/>
        <property type="gene ID" value="CP500_013960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="54" mass="6101" checksum="AF291646CB47AE26" modified="2018-01-31" version="1">MAKDIYHYNVRTALEKDGWTITDDPFPLRLGLRGVLIDLGAKKLLAAERKGQTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZC3</accession>
    <name>A0A2G4EZC3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54861">
        <property type="protein sequence ID" value="PHX54861"/>
        <property type="gene ID" value="CP500_013855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="7198" checksum="6A07DD0CA0EA6CC6" modified="2018-01-31" version="1">MRNENLGNLGCRHCRHFQQQGRRGGHCHLLGVDVHSGWKACPLVLPPFAPSWEHPETARVKQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZM1</accession>
    <name>A0A2G4EZM1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54959">
        <property type="protein sequence ID" value="PHX54959"/>
        <property type="gene ID" value="CP500_013115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="351" mass="38550" checksum="ECD821E0DF28355C" modified="2018-01-31" version="1">MANYTIFDEQYYLASYPWLKPAIDAGIIKSGREHFEKFGQAGGLTAVSRYFDEQNYLAQNPDIVPSIRNSSNPNAPFASGLDHFIQFGYEEGRTRVSLDYDEAFYLKRYPVLVPFVQNGTFKSGLEHFIKFGAKEGLYANTFFESQYLLKHPAVATAVKAGVFKTGAEHYRKFGQFEPALPFVDIIFFGTSGNDTVQGFGVENVNISGVQYALDANGRLPFQSPGRDEFDTLIGGSGRDNFVLAVTIPGIGGSRPTPVNVQFYDGPGFAKIQNFTEGQDTIQFGSASFDKFLVFPINNNRDLAIQTNGLPFFTPNGGDQLSYGDTIAVIEGAGNLTLKPLFIPTKLGTFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZM2</accession>
    <name>A0A2G4EZM2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Magnesium chelatase</fullName>
            <ecNumber evidence="3">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_013125</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + Mg(2+) + protoporphyrin IX = ADP + 3 H(+) + Mg-protoporphyrin IX + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60492"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.6.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Porphyrin-containing compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mg-chelatase subunit H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54961">
        <property type="protein sequence ID" value="PHX54961"/>
        <property type="gene ID" value="CP500_013125"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10150">
        <property type="entry name" value="CobN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011771">
        <property type="entry name" value="BchH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003672">
        <property type="entry name" value="CobN/Mg_chltase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022571">
        <property type="entry name" value="Mg_chelatase_H_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44119">
        <property type="entry name" value="PTHR44119"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02514">
        <property type="entry name" value="CobN-Mg_chel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11965">
        <property type="entry name" value="DUF3479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02025">
        <property type="entry name" value="BchH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3479" evidence="10">
        <location>
            <begin position="24"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1331" mass="148005" checksum="1C2CBF9F544A1703" modified="2018-01-31" version="1">MFTHVKPTIRHIVPENLQGRSLLKVVYVVLEPQYQSALSAAVRSINKKNPNLAIEISGYLIEELRSPENYEAFKRDVADANVFIASLIFIEDLAEKVVAAVEPVRDRLDVAVVFPSMPGVMRLNKMGSFSMAQLGQSKSAIGEFMKKRKEKSGSSFQDGMLKLLQTLPKVLKYLPLDKAQDARNFMLSFQYWLGGSQENLENFLLMLSQKYVFKDLSKSSFQEPVVYLDMGIWHPLAPSMFEDVKSYLNWFNARTDISADLKDPLAPCIGLVLQRTHLVTGDDAHYVAMVQELEAMGARVIPIFAGGLDFSKPVETFFLEVVAKGVTPLPIVDAVVSLTGFALVGGPAKQDHPKAIESLKKLNRPYMVALPLVFQTTEEWEDSDLGLHPIQVALQVAIPELDGAIEPIIVSGRDGATGKAIALQDRIETIAQRAMKWATLRRKPKLDKKVAITVFSFPPDKGNVGTAAYLDVFGSIYEVLKALKGNGYDLPELPDSAEKLMQEVIHDATAQYQSPELNVAYRMSVAEYEEFTPYSERLEENWGPPPGNLNSDGQNLLIYGKHFGNVFIGVQPTFGYEGDPMRLLFSRSASPHHGFAAYYTYLERIWGADAVLHFGTHGSLEFMPGKQMGMSVDCYPDSLIGKIPNLYYYAANNPSEATIAKRRSYAETISYLTPPAENAGLYKGLQELSELIASYQTLKDTGRGVPIVDAIVEKCRLVNLDKDIDLPPEQERGVAAGMTAEERDNLVGLVYRKLMEIESRLLPCGLHVVGKPPTAEEAIATLVNIANLDREEDGLVSLSRIIALSCDRNIDDIYTNNDKGILTDVELLQNITLACRDAVTALVKEQTDAEGRVSLVSKLNFFNMGKKTPWIESLHAAGYKKVDVDLIKPLFEYLEFCLEQVCADNELGALLRALEGEYILPGPGGDPIRNPDVLPTGKNMHALDPQSIPTTGAVKSAKVVVDRLLERQRLDNGGNYPETIAVVLWGTDNIKTYGESLAQVMWMVGVKPVPDALGRVNKLELLSLEELGRPRIDVVINCSGVFRDLFINQMNLLDKAVKMAAEADEPLEMNFVRKHALKQAEEMGINLRQAATRVFSNASGSYSSNVNLAVENSTWESEAELQEMYLTRKSFAFSSDNPGTMEQDRQIFESSLKTADVTFQNLDSAEISLTDVSHYFDSDPTKLIGSLRADGKQPTSFVADTTTANAQVRTLSETVRLDSRTKLLNPKWYEGMLSHGYEGVREISKRLVNTTGWSATAGAVDNWVYEDVNGTFIQDEEMQKRLLNLNPHSFRKIVSTLLEVNGRGYWETSESNLDRLRELYQEVEDRIEGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZN6</accession>
    <name>A0A2G4EZN6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54969">
        <property type="protein sequence ID" value="PHX54969"/>
        <property type="gene ID" value="CP500_013180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013814558" evidence="2">
        <location>
            <begin position="26"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="128" mass="13270" checksum="CDAC06374730B1C0" modified="2018-01-31" version="1">MQSKTKIWLGIGACVLTSVAASAIASQNDSSVNQFSPISLLSNAANSSMSNSKPVKPIVLMSSSGGEQGESGEGKKPKPRKKSSFTSEFYLTDSNVTMTASKGGEGGEEGEEGEKGESGEKGESWKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZP7</accession>
    <name>A0A2G4EZP7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54983">
        <property type="protein sequence ID" value="PHX54983"/>
        <property type="gene ID" value="CP500_013250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="26687" checksum="C2C7FE4CE4B1F1DC" modified="2018-01-31" version="1">MTSINMLRQEADAIGITEEEARKYGNIRHRRTWSLAIEHHLSMQGLGDRIQPSFTNPNLDSSFPSTDSPQTENRPEFKDYSIQMTANLGESRHTIEDQITSVVAPRHPVLHPVRHSKSIHYLKQAGSFDQVVQNHIKALKSASHTHTNSSDLSIINWVCPECGPQGDINCHLCEGVGNITDIAAIGWTLAYMEMLGCSAREIEPIRRLSPASNILELNLATCVAIKQSAEILARTEKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZX0</accession>
    <name>A0A2G4EZX0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase M43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_012895</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55062">
        <property type="protein sequence ID" value="PHX55062"/>
        <property type="gene ID" value="CP500_012895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04276">
        <property type="entry name" value="ZnMc_MMP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033413">
        <property type="entry name" value="DUF5117"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033428">
        <property type="entry name" value="DUF5118"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032534">
        <property type="entry name" value="EcxA_zinc-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034032">
        <property type="entry name" value="Zn_MMP-like_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16313">
        <property type="entry name" value="DUF4953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17148">
        <property type="entry name" value="DUF5117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17162">
        <property type="entry name" value="DUF5118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5118" evidence="4">
        <location>
            <begin position="63"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5117" evidence="3">
        <location>
            <begin position="126"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4953" evidence="2">
        <location>
            <begin position="543"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="956" mass="108520" checksum="C6C207FEA64C15AB" modified="2018-01-31" version="1">MKNWTSTKNSKNQQNKNPTKNWAVKFFILSLVFLIFSLYQGLFLPYSLSAPPEKEKSSEQALQPFDVVIKDAQKSEGMFTLYANKATDKVYLEIKPEQLNKKFLCFVTLASGLGEAGILSGLPFGDFLFQLRKVQNNIQFVIPNINFRTSPGDPQAGSVERAFSESILYSLPLKSIHPVRKTLLIDLGDLLMSEKRDLPGVKSFLPMILGSPYSIDADKSYFKEVKAFPLNVEITSVYGFSSENDSSVTYLPSIPDSRAFNLRIHYSFSEVPLNNGYRPRLADERVGYFLTAYKDFSDNSSREPFVRYINRWHLQKQIPTAPLSPPVQPIVFWIENNVPLEYRNAIREGILEWNKAFEKAGFTEAIKVKQMPDNAKWDPADVRYNTIRWSSSFNPEFVGLGPSRTNPLTGEILDADILLDANIVRQIKQDYRSLVAQNRSIAKSFQGRNGANTNPCQFGMYSRYLKLLENGNLETEKKQNSPGGIVDDLPTLVERYQEQKRSPMSRLMSDSDLCFGLESSRQFAMGAMSMSLLGNTTPNSSEIDNYVNQYIRFVTAHEVGHTLGLRHNFHGSTMLQPEELNNTQLTRTQGLVASVMDYVPINLAAPGSVQGDYYPMIVGPYDDWAIEYGYKVLGAVNPSNELPMLQQIASRAAESQLAYSTDEDAVDSLDPAANTFDLSANMLNYSQSQLDNSRVMWKRLEKRIPVGDDGYNELRVMFDSVFGYYFQQVMNATLYVGGQSFNRSRPGDPQGKLPFVPIALTQQREALATLDKYVFAPDAFSFAPELLNKLAPSRWNHWGSPALVFPLDYPIGDRITFLQRFVLRVLLSPERLARLRDAELKSSPESALRLPEVFDTLQKNVWQEVLQPTNKKMEISTFRRSLQREHLAILMGMVLRKTNVPEDARSLAWYELRQLREGLSKTIRNLDRSADAYTRAHLEETRDRISKVLNAQIESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F031</accession>
    <name>A0A2G4F031_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000064">
        <property type="protein sequence ID" value="PHX55120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55120">
        <property type="protein sequence ID" value="PHX55120"/>
        <property type="gene ID" value="CP500_012480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="15930" checksum="FA289B8E83BBFC60" modified="2018-01-31" version="1">MIESSSESRSEFENLPDHTLVYRGLRKGWIDRDRSIVKLDAYYLRQRIKEEGISVNFSIEQSLSALKNCAGVASLNVGEIRELGLNVVRDSSSHGSIMGLPIGVNLTSNPFRDYCLTIKARSPLTPLKKGGTGVFSKSPFLRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F040</accession>
    <name>A0A2G4F040_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55132">
        <property type="protein sequence ID" value="PHX55132"/>
        <property type="gene ID" value="CP500_012155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="3">
        <location>
            <begin position="76"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="312" mass="32014" checksum="3B8D3964AC188987" modified="2018-01-31" version="1">MANSSGPPPIVFILLFFLLAGGGAFFFLKKPASQDASNTPTPASGDVTPPPVTPATGGAPPVAATSFAPPASVAPGTAVRIDGSTSMVTINLNLKNGFQTKFSGATVNAKANGSANGIKDLVAGTADIAAISQPLTAQEKSQGLVEVPVALDAIALVVGTNNPFKGGLTSAQVQDIFKGTAQDWSKVGGPAGPIKVINRPEVSGTHQAFKEQVLKGANFGTGSNITRLDRDATTPLLQALGNNGIGYATFAQVVNQKTVRVLPIDGATPDAGNYAYKRQLYYAYKNPPTQAVKDFLGYATSPDGQKAMLAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F081</accession>
    <name>A0A2G4F081_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mercuric reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_012320</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="6">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55161">
        <property type="protein sequence ID" value="PHX55161"/>
        <property type="gene ID" value="CP500_012320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016668">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0274">FAD</keyword>
    <keyword evidence="2 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="10">
        <location>
            <begin position="39"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="9">
        <location>
            <begin position="378"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="212"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="7">
        <location>
            <begin position="76"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="511" mass="55541" checksum="8C14A6F1EBE564CE" modified="2018-01-31" version="1">MSQSKVDRVIVPPMDEYNQKLVSYLHPSDWVNPQPASRYNLVVIGAGPAGLIVAAGAAGLGAKVALIEKHLMGGDCLNVGCVPSKALIRSSRTVGDIWESSKFGVNVPNSVEVDFAAVMERMRRIRAGISDVDSVQRYQEKLGVDVFLGSGRFTSNNTIEVAGQTLGFKKAVIATGARALQPQIPGLQATGYLTNETVFNLTERPQRLAIIGAGPIGCELAQAFRRLGSEVVLLHKNAQILDKEDADAANIVQQAFIREGIQLILESKIERVEKTNLGKTIYYQLQGKEASVTVDEIIASAGRSPNVEGLNLEAIGVEYDTQTGVFVNDNLQTTNPRIYAAGDICMKHKFTHAADFAARIVIQNTLFFGRKKLSALTIPWCTYTSPEIAHVGMGEAEIQAKAIDVDTFLIPFSQVDRAIIDGEDEGFVKIHVKKGSDKILGATIVAQHAGDMISEITLAMVNNIGLGKIASVIHPYPTQADAIRKAGDAYNRTRLTPFVKDLFNRWLAWTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0M2</accession>
    <name>A0A2G4F0M2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55305">
        <property type="protein sequence ID" value="PHX55305"/>
        <property type="gene ID" value="CP500_011410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="12"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="226" mass="25522" checksum="9439560D5C803A5D" modified="2018-01-31" version="1">MKTEAFSELFPLFKGANPETLGGLLSNAVKHEYPAGRAVLMEDSWGNAIYFVVSGWVKVRHLSGDRAISMAILGRGAFFGEMAILDESPRSNDVLALSPVRLISVTAQRFIQTLFKDPQLHHRMLQLMVRRLRQTNLRYQLRNRQPAVKLANTLVELAENYGQKNAQGKDIFNIPYQDLADVTEIGIDETSKIMEKLDSKGWIGVDPERQTIHLINLKHLINLANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0N5</accession>
    <name>A0A2G4F0N5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55316">
        <property type="protein sequence ID" value="PHX55316"/>
        <property type="gene ID" value="CP500_011470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013612821" evidence="1">
        <location>
            <begin position="24"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="219" mass="22219" checksum="09EF0B71E76D54D3" modified="2018-01-31" version="1">MKFEILAATALLMAIGFTSPVKAENPGDVKQLLETKSCSGCDLTGAQLSGIDLSGADLSGADLSGANLIGTNLNEAKLNKANLSNAKLPGASLIAARMHGANLEQADLSRANLNLAGMVIANLKNANLSSSNLIGANLESANLTGANLKNVRQSLLNLANVSLRGGSLSGMDMLGVNLRDANLTGANLTGANLVGSDLTGANLRNANMANVELKNAALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0S5</accession>
    <name>A0A2G4F0S5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WYL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55369">
        <property type="protein sequence ID" value="PHX55369"/>
        <property type="gene ID" value="CP500_011260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="117"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="283" mass="32928" checksum="3763EA7E1631AF6B" modified="2018-01-31" version="1">MTRRKETITLSIPTGTKEQLEAIALRLGIKWGKSPSVSGLLVAIAQQKIEVGEPFTLNSVQVQSLNKAVKFLNDSGEVEAAQIVMALLLDKANLETPFRQQLLQQVSQTAEAWRIRLNQLIDDRQPFRLFYQSRKDKVSEFTARSAKIRLYDKRLYLEIWCDEADSREIPELAHNRCLRLDKIVNLLPASENWRETIDYLEVHLHFFKGLAGNYEFKPDEDVANEMVGDVRHVVKRVSSIFWLFRDVHRYGKDCEIVSPLKLRDRFQQKLIALCRLYNLEIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0T3</accession>
    <name>A0A2G4F0T3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55384">
        <property type="protein sequence ID" value="PHX55384"/>
        <property type="gene ID" value="CP500_010950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="348" mass="38418" checksum="098C277377782522" modified="2018-01-31" version="1">MKTLLRLLLKSHHQRNRSGPAQTDKGMTLVELLVGSIMAFLIITPMLGFVVDMLNTDRREQVKSNTEQDLQAAVDFISQDLSQAIYIYDNTAINDPIKGIRSQLPENTNTTNKIPILVFWKRQLMKKSIPVDPSTVKPNGCNDDKCNDTYLLSLVAYYQFKDSDSTWCQPSGGTCPSRIARYEIRDGIKNPLTQAYYADSDTTTGQRKDPAFNPRFELTKPTVNVTDAAGLTDAQSGARNPQVLVNYIDHSPPIGKIIDQAECQKALGNPSIKIGVTTTAVPEATLKITDVSTHSFYACVDTSNNIARVTIRGNSLRRLQTDANYDPNKLAFFPTATVQVKGLSGLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0X9</accession>
    <name>A0A2G4F0X9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NAD(P)H-quinone oxidoreductase subunit 2</fullName>
            <ecNumber evidence="9">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">NAD(P)H dehydrogenase subunit 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">NADH-plastoquinone oxidoreductase subunit 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">NDH-1, subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ndhB</name>
        <name evidence="12" type="ORF">CP500_011080</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="function">
        <text evidence="9">NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the complex I subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55406">
        <property type="protein sequence ID" value="PHX55406"/>
        <property type="gene ID" value="CP500_011080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00445">
        <property type="entry name" value="NDH1_NuoN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010096">
        <property type="entry name" value="NADH-Q_OxRdtase_suN/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045693">
        <property type="entry name" value="Ndh2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19530">
        <property type="entry name" value="Ndh2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01770">
        <property type="entry name" value="NDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="5 9" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="3 9" id="KW-0874">Quinone</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Ndh2_N" evidence="11">
        <location>
            <begin position="12"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="10">
        <location>
            <begin position="129"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX55406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="523" mass="55385" checksum="0D2495D11F9E44F8" modified="2018-01-31" version="1">MDFATLAAQLNAGTILPEGIVIVTLLVVLVGDLIVGRSSSGWTPYVAVGGLLAAVGALCLQADNTNTISFLGGFNSDALSLVFRGIIALAAAVTILISVRYVLQTGAALAEFIGILLSATLGGMFLSGADELVMIFISLETLSISSYLLTGYTKRDPRSNEAALKYLLIGASSSAVFLYGLSLLYGLSGGETTLSAIASHLSTVNEGQSLGLVIALVFAIAGIAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLTTVFPVLTEQWHFVFTALAILSMVLGNVVALAQTSMKRLLAYSSIAQAGFVIIGLVAGTEAGYSSMIFYLLVYLFMNLGAFACIILFSLRTGTDQISDYSGLYQKDPLLTLALSICLLSLGGIPPLAGFFGKIYLFWAGWQAGLYGLVILGLITSVISIYYYIRVVKMMVVKEPQEMSDVVKNYPEVRWNLQGMRPLQVTVVLTLVGTTLAGILSNPLLNLANDAVSKTPMLQSALSHVQPVVAAKIESNLLSRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F131</accession>
    <name>A0A2G4F131_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55167">
        <property type="protein sequence ID" value="PHX55167"/>
        <property type="gene ID" value="CP500_012350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="22170" checksum="2E7980C615BF7F94" modified="2018-01-31" version="1">MKTNLLEKLDTQTEQRLILQGISWQDYLTIDSVLEDVPGLRLTYCQGLLEVMTLSPRHEREKTTIGRLLETYALAKDLDLHGCGSTTYRNQAKARGLEPDECYCVGELKDIPDLAIEVIVTSGGIDKLQVYLGLNVSEVWFWQDGQFSLYQLQSGTYQKCDRSQFFPELDLVSLASFVQPDNQPAAVREFFNSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F174</accession>
    <name>A0A2G4F174_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_010415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55511">
        <property type="protein sequence ID" value="PHX55511"/>
        <property type="gene ID" value="CP500_010415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
        <property type="entry name" value="PTHR31088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="54"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="261" mass="28412" checksum="C99213F60A5F4BA6" modified="2018-01-31" version="1">MGLFDRISRVVRANLNDIVNKAEDPEKILEQSVMDMQEDLVQLRMAVASAIAAQKRTQTQYNQAESQSNQWQQRAQLALQKGDETLAREALVRKKSHEQTATTLKASLEQQSTQVESLKRNLIGLESKISEAKTKKDMLKARISAAKAQEQLNNTIGSLNTGSSMAAFDRMEEKLLQIEARAGASAELAAGGSNLEEQFRLLESGGGVDDELAQMKAQLAGGSVSQPQLPESGKTAAANSAESSPVIDAELEELRSQLNKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F178</accession>
    <name>A0A2G4F178_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55217">
        <property type="protein sequence ID" value="PHX55217"/>
        <property type="gene ID" value="CP500_012020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8239" checksum="28CC7425B1BC876D" modified="2018-01-31" version="1">MDDFTENPGVRSLALEPNYIVLSRVEPRFWNLLIARTLNIINKNHIFVNKLRNTHFIETINRVAKQNFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1D4</accession>
    <name>A0A2G4F1D4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55570">
        <property type="protein sequence ID" value="PHX55570"/>
        <property type="gene ID" value="CP500_010085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="9"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="137" mass="15446" checksum="D7144E4BFCEC871D" modified="2018-01-31" version="1">MSKTYVSASLRRMVCDRANGYCEYCLIPEALALSSHQIDHIIAEKHSGETVESNLALSCSICNKNKGSDIASIDPETGEVVRLYNPRKDRWEDNFQIQTESGTIQPLTAIGRVTVRLLQVNRAECLTERKLSIKIRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1G3</accession>
    <name>A0A2G4F1G3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Helix-turn-helix domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55585">
        <property type="protein sequence ID" value="PHX55585"/>
        <property type="gene ID" value="CP500_010100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="17976" checksum="1AFA53D968FB3EC8" modified="2018-01-31" version="1">MASTNDRFVEAESRWDLKTLYADLAAVKGKPLTPVEKLHLRGLLCGNSPAEIAEKLQKNPKGVETDLCATIYRYVKGFVGKGIEKIENWRNIAEWLDDAGYKTQSSAKLPATNLLPEKSIVNISNISIEKNQIVIVVKIQIPTSLDSELPIQNLDLDDNNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1L9</accession>
    <name>A0A2G4F1L9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">priA</name>
        <name evidence="13" type="ORF">CP500_009780</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55635">
        <property type="protein sequence ID" value="PHX55635"/>
        <property type="gene ID" value="CP500_009780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040498">
        <property type="entry name" value="PriA_CRR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18319">
        <property type="entry name" value="PriA_CRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="322"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="595"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="556"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="587"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="863" mass="95941" checksum="7CFBBE5BBBD001B8" modified="2018-01-31" version="1">MSTVTFALSTPSAAEPGASYGSDRPPSRPTVRAQWIEVLVDSPLRGAGDSPGEQNKLFTYRLPPELTVQPGDILSVPFGSQQVGAIAIRFISQLPPDLDPAKVKDVEDIVSSGFFDPTYWELLDRTSSYYCTPLIQVIRASLPPGLLSHSVRRIRLVKDAISPNAEVFLNPAASQILQLLQAQKNGDYTWKYLQRQVKGAGAYRGLRDLLTRGWVESYLEPPHPPKPQLKPAVTLIVSPFVTDLTQRQQEVLEVLRRAGGEMWLNDLLKICSTSSYLVKALEQKGSVVIDQREVLRGDRGIAQIPDAPKTLTHFQAQALAFINTFSGFRQVLLHGVTGSGKTEVYLQAIAPILASGKSAIVLVPEIGLTPQLTDRFRARFGEQICVYHSALSDGERYDTWRQMLTGTPQIVIGTRSAIFAPLPHLGLIILDEEHDSSFKQDDRAPCYHARTVAKWRAELENCPLILGSATPALETFVETKINNYSLPTIHYLSLPERIYSRPMPPIQIVDMRQELRQGNRSIFSVSLQNALEQLQARQQQGILFIHRRGHSTFVSCRSCGYVMECPNCDVSLSYHHVGEGTAEILRCHYCNHTERHPQNCPECSSPYFKNFGSGTQRVEQELTRLFPQLRAIRFDSDTTRNKGDHRRLLTQFADGEADILLGTQMLTKGLDLAGVTLVGVVSADGLLNLSDYRASERAFQTLTQVAGRAGRGDDPGRVIMQTYTPEHRVIQAVRQHEYTSFVETELAERAALNYPPSGRLILLRLSSLDAAEVAVCAVQLASVCHEYIERLSIPGCELLGPAPAAIMRVANRYRWQILLKLPMDESVDLSDLIGLRDSLRDSFASRTPRSVSLTIDVDPLNFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1P7</accession>
    <name>A0A2G4F1P7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55668">
        <property type="protein sequence ID" value="PHX55668"/>
        <property type="gene ID" value="CP500_009670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="168" mass="18617" checksum="14A0391CA8AA065E" modified="2018-01-31" version="1">MVRYTLPQSPETILTVKGKDSAKAREEAMDQLMQLIDSDKLSTELPEGFGPKQFVEVKDLEDGTSETEDAITEAIQILSNLASLKLKVMESREEALKIRAAIDILFTDEPVTAEEISSLKDGFKVLKNFAQANVRYREARGKAESARAILDEALQSPESENKAQKSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F210</accession>
    <name>A0A2G4F210_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55804">
        <property type="protein sequence ID" value="PHX55804"/>
        <property type="gene ID" value="CP500_008945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="169" mass="18040" checksum="276AB75048EF307E" modified="2018-01-31" version="1">MKSISRIFLNLILSLILAFGWVILSATPAFALPKTNINYTNINLSDRDFSNSDLAGGTFVASEMRNTNFQGADLTNAILTKGVLLKANLSGANLSGALVDRVTLDGANLTNANFTEAILTRTRFFNATISGADFTDAIIDTYQVKLLCKKADGVNPVTGVATRESLGCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2B2</accession>
    <name>A0A2G4F2B2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55889">
        <property type="protein sequence ID" value="PHX55889"/>
        <property type="gene ID" value="CP500_008310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="32671" checksum="AD698B2958AD620E" modified="2018-01-31" version="1">MQFINPKTDFAFKKIFGDEQNKDILISFLNAILYQGNSAIESLEILNPYQPPKIRGVKDTYLDIRAKLNNEETVIIEMQVLNVEGFEKRILYNAAKAYSIQLDTGADYTLLNPVIALTITDFEMFPNLDKVISNFVLKEKDFLVDYLIYDIELVFVELPKFSKKLEELETLTDKWIYFLKNAKSLQLVPEQMEEVPALQKAFGVANRVGLTREELEDLEHQEIYIQDQRNAITKAVKQAVSQAVSQAVNEKAIEIAKGLLDVLDEATISQTTGLSIEEIQKLKQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2D3</accession>
    <name>A0A2G4F2D3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55909">
        <property type="protein sequence ID" value="PHX55909"/>
        <property type="gene ID" value="CP500_008315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="18586" checksum="8988A1FCCA0F7107" modified="2018-01-31" version="1">MSDPLFWLGMSILLVAVSLTAVLVTLIPAVQALTRAARSMEKLADTLCRELPPTLDAIRLTGLEISELTDDVSEGVQSAGDVVKQVDRSLGTAKKQAQNVQVTTRSVVTGIKAAWKTLTRKPISGRSRGGDRLSPNQRSAISLRDSARQRNSEGSHLDGDSEEFDQVRSKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2K3</accession>
    <name>A0A2G4F2K3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FkbM family methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55979">
        <property type="protein sequence ID" value="PHX55979"/>
        <property type="gene ID" value="CP500_007990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="79"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="244" mass="27602" checksum="55347B3406F5AD86" modified="2018-01-31" version="1">MFCNKIIQLLQRKTRAQKLGIKFPRVANFNLPDSLIIQGKRQSVKLPSEKGMDGEFIEVLLDDCYGLEQLPQSLLKIIDIGANVGLFSIAARNRFPQAVIHAYEANPNLEKYLQNQSLIASFEYFMEAIGAEDGKVVLDIREVSGKTRSTVSANGDIPMISFKSAIDRIGGQVDLAKIDCEGAEWLLFEDTEIWQFVQNLSLEYHLWSGHTHTETRQVIENLGFQINKQIPIDKWYGLILASRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2L5</accession>
    <name>A0A2G4F2L5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CP500_007835</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55989">
        <property type="protein sequence ID" value="PHX55989"/>
        <property type="gene ID" value="CP500_007835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="365"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="450"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="748"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="11">
        <location>
            <position position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX55989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="958" mass="107591" checksum="753B852CB060DEB6" modified="2018-01-31" version="1">MVFKLLDKLPLRTVLIVPFVLQIVGAVGLVGYLSFRNGQKAVNNLASQLMSEVSSRVEQNLQVYLTTPHQINQSKLDAVKLGLLNINDLSSWEKYLWRQVQLYPYINFTSIGNKNGEYRTGEKLSNGSLMINVSGKSTGFDFYSYNTNNTGDRTTVAAVVKNFDIRQHPSYALAALEIKPTWSSVYVSFLEPTLIISALQPVYDDKKQLEGVLITALRLDHIGQFLNSLRVGKSGQAFIIEKNGTLLATSTSEKPFRTRGNKKELFQAEESVDPSTQATAKYLAANFRELKKIKKSYLLNFKIEGKQQFVKVLPFQDGKGLDWLIVVVVPEADFTEEIDTNTRMTIWLCLAALGVAVIIGILTSRWVTNPIWRLNIAAKNIAKGEWDKTVEMERADELGELGKSFNSMAQQLQQSFETLEHRVQQRTAELAVAKDKAEVANQAKSTFLANMSHELRSPLNAILGFSQLMTRSQTLSLEDQENMNIISSSGEHLLTLINNVLDLSKIEAGRTTLNPKKIDLYRLLCDVEDMFQLKADDKQLQLIFDRAPDVPQYVETDELKLRQVLINLLNNALKFTDDGGVSVRVSKQVEARNQEAIGEKIELSEKSLNLKIPANNHVEDFQVSLYKNANFTSQIPINDSTYDSSFFLHFEVEDTGPGIAEEELHSLFEAFVQTKVGKESQEGTGLGLPISRKFVELMGGEMSVSSCVGQGTNFKFDIQVIGVESAEAESIKPTRHVIALEPNQHPYRILIVDDKPLNRQLLVKMLNPLGFQLKEAINGQEAIEIWDSWEPHLIWMDMRMPVMDGYEATKQIKGTVKGQATAIIALTASVLEEERAVILSAGCDAFMRKPFREAEIFDAMHKHIGVRYIYEKTSQANVLKTNNRDLEVFTVNAFNALPQQLVAELKQAILNVDMDLIDSSIEKISLQDQLLGSAIANCIDNFEYDKVLNLIAETKYHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2T1</accession>
    <name>A0A2G4F2T1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4347 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56084">
        <property type="protein sequence ID" value="PHX56084"/>
        <property type="gene ID" value="CP500_007190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025592">
        <property type="entry name" value="DUF4347"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14252">
        <property type="entry name" value="DUF4347"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4347" evidence="2">
        <location>
            <begin position="3"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="798"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="802"/>
            <end position="860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1142" mass="117124" checksum="05A589D63AB02156" modified="2018-01-31" version="1">MSPQLKQWGKALTENADILLYGCEVAKGETGQNFLKRLSEITGANIAASATPTGSAELGGDWNLEVQTGPIAAAIPFNAKALKTYSGVLGLAPKVTAVTATTADGSYGVGSTIAITATFDAAVTVTGTPRLQLETGTTDQFATYASGSGGTALTFNYVVQTGDSAADLEYLATNALTLDGGTIKDNLAADAVLTLPALATDNSLGGSKAIVVDTVAPTAKLGIIPNPNIITSPGTSKSLTVTFSDNNAVDVSSLDSYDIFINGPGGDIAAQFVSVDTNSNGTPRTATYSFTTPFTLGSTIYTVKLEGSQVKDSLGNFAVAGSLGTFNLTGPIPPTPVTPTPTPVTPTPTPTANPNQAPIVYNPVWTQSRARGWSSNTTFEFASDTFIDPNPGDTITYTVTAIDNNSVTEGEDYIWKNGENGGLYKQKTNNASVTTIPEIFDGPNASLKFDPTTRTLSQVPGKNLSLPQWVEVKGTDNNGKSVSELLKLVGSNRTGFVIDDYIAGANVFFDANKNGIADPNEPKGTTDGKGAFAFDIPFSTFDTNKNGKLDPNEGNLVAFGGTDIGTNLPLETPLKATPDAEIITLLTSIVAELADRGLTVNEANAKVTSAFGIPSDIPLNYVDPIAATQGGQPSAKAALTTMLVAQNSITQTAGLIEGASNLTVGDAVKQIVSTIADRIQTGTLDFSKSEQVGALIVQVGDRVKAIDPNFKAQNVSDAKTELAKVIAASNQRVVDAIATNTDPTQLQKQVAVIQKVALGETTQDFKAFGAGQKTIDSLVAENTGAALEKRILTATNTLLTPTPTPTPTPTPTPTPTPTPTPVVTTPTPVVTTPTPIPIPVTTPTPAVTTPTPAVTTPTPVFTPTPPQTIALPIAFTVTNAPAPTGLASGNIGSSSNDVIVAIDANSPVYGNKGNDTLIGNSENNTFFGGKGDDALFGDDGNDLLFGNDGNDTAIGGSGNDTELGGKGDDLLYGGDGNDVLSGDLGNNTLAGDAGNDSLYGGENNDALLGGNGSDFLYAKEGNDILTGVDGTAANPGLGEIDTLIGAEGNDTFLLGNATKFYYSDGVDTATGAGDYALIVGFNPIEDIIQLQGASSTYVFGASPTGLPVGNAIFKKTAGADELIAIVQAVSTFGPDSTSLRFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2T2</accession>
    <name>A0A2G4F2T2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56045">
        <property type="protein sequence ID" value="PHX56045"/>
        <property type="gene ID" value="CP500_007670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="25"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA" evidence="2">
        <location>
            <begin position="182"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="30059" checksum="24085E3624B5290A" modified="2018-01-31" version="1">MNQQISAHSQKLLLQIGRKIRKTLDINGIWQQTVNSLGPTLGANRCIICPYEGSSRKVKVAAEYCQESFPAMLGVEISLETPHFIEAITTLEPVIVESFATDDPFCRQSMLVVATAYQDQANGIISLHRCGQDNLGNNIAHRPWTECQIEFAQELADQVGSAIALATLYQERSERVTELSQLKKQFMLKASHELRTPLNHIIGYLQLTVDDMADDPIEERAFIQEAHRSALHLSKVISNVLDFIQLSDACQTHADLSAVRSREKYSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2U4</accession>
    <name>A0A2G4F2U4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GHL10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_007485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56072">
        <property type="protein sequence ID" value="PHX56072"/>
        <property type="gene ID" value="CP500_007485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003790">
        <property type="entry name" value="GHL10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02638">
        <property type="entry name" value="GHL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="GHL10" evidence="3">
        <location>
            <begin position="130"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="568" mass="63561" checksum="1A4118AFA2E87D2E" modified="2018-01-31" version="1">MPDARSVPHLSEKGYSIAIPQQQRRFLSAVSAVLTSSFISQFIWLFVENQPVVAQTSAYCQLSKEQVNQKEDLRRAALSGKPESQQAYFAILNKHTRESAECRQKNWPQTQAVWLRLYPCDVRAGELDRVLDKVVNKGYNQVYIEVFYDGQVLLPAADNPTAWPSVVRNRGYEKYDLLENAIAKGKQRGLKVYAWLFTMNFGYTYSQRSDRQQTLAKDGQNQTSLTVVQDAGINDDSGEVPGNQAFIDPYNPQARQDYSLLVNQVLKRRPQGMLFDYIRYLRGVGPASVATKVKDLWIYGSASQQALLQRANNQQGRDLIQRYLTKGFINVADVQAVVKQYPTEKEPLWQGRIPTPKPTPKPTPTPLPKKINFIATTVAQNPTNSQPNISTPTPKLTPTPTPKPTPMLPDTGTLQKDLWKLSVAHAVQGVLDFFSMAIQPAQKMGIPVGAVFFPNGNQTINQGGFDSRLQPWDRFPTSVEFHAMSYGNCGDTSCIVPQVQRTVSIAPPGAKIIPAIAGDWGKPLKNRPSLEIQMQAIRAATPQINAVSHFSFGWQEPEDERARQTCRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F341</accession>
    <name>A0A2G4F341_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase M15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56166">
        <property type="protein sequence ID" value="PHX56166"/>
        <property type="gene ID" value="CP500_006895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="219" mass="25088" checksum="AB1DD4F948AFF6E1" modified="2018-01-31" version="1">MKKPQTVKSLEELGRIQLSKSFFMREFLYSEISQIESIPNIPDDPDLAIAAGRNLCEKVLEPLQDALGRISVRSAFRASAVNKIGSENQNQYSCASNEANYAGHIWDVRDQDGYMGATACIVVTSFIPYYEQTGDWTALAWWIHDHIDAYSEMTFFPKYAAFNITWHENPECKKVIYSYVKNPHTQKNSGYLTKTGMENFSGSHEQFYQEFMRQLHPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F395</accession>
    <name>A0A2G4F395_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_006625</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56232">
        <property type="protein sequence ID" value="PHX56232"/>
        <property type="gene ID" value="CP500_006625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013686">
        <property type="entry name" value="Polypept-transport_assoc_ShlB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08479">
        <property type="entry name" value="POTRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013814560" evidence="3">
        <location>
            <begin position="23"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="5">
        <location>
            <begin position="209"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA_2" evidence="6">
        <location>
            <begin position="281"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="5">
        <location>
            <begin position="382"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Omp85" evidence="4">
        <location>
            <begin position="470"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="795" mass="85692" checksum="10378058C59B06E2" modified="2018-01-31" version="1">MRLSAVLIAVLTVSATFGLSNSASGQTSYSESAEKVSAAIPPVDAIESPVELTENPPENRVVVKASKIESLKKIAAAPARGENDREPRNRLTEPSPPIATPSFQLKPDVESNPGIASASPNALPDAKQDDSPVPPSEAAVLPASIAVDRAKQDESEATQNAQIPPTRPAPTRPAPATPPANRIPVPPSSAPQPRQTPAPTGPAQPQVLVAEVTVSGVTGDLESEIYRVITTQPGRTTNRSQLQQDINSIFATGFFKNVRAVPEDTPLGVRVTFIVQANPVLRGVQITGQKVLPQSVIDESFRDQYGKTLNLRRFEEGVKKINTWYQDNGYVLGQITEAPQVADNGTVTLQVAEGQIESIDVRFLNKEGEATDATGKPIGGNTRHFVIAREVEQKPGDIFNRTKAERDLKRVFGLGIFEDVRLALEPGTTDPRKARVIVNVIEKNTGSLAAGAGLSSATGLFGTVSYQQQNLGGRNQKLGAEVQIGERQNLFDVSFTDPWIKGDPYRTSYTINAFRRRSISVIFDGGDQEVRLPNDDRPRINRTGGGISFTRPLSRNPFANSEWTASVGFQYQRIAITDRKGRRESEDELGNRLSFSNSGSDDLTTLQAGAVRDRRNDPLRPTSGSLLRFGVEQSIPVGSGSILMNRLRASYSFYLPVKYTNFTPGPQTLAFSFKAGTIFGDLPPYEAFALGGANSVRGYNEGDMGAGRTFLEGTVEYRFPIISFIGGALFVDAGTDFGTGKDVPGDPAGIRKKPGSGYGYGLGVRIQSPLGPIRIDYGINDTGDNQIHFGIGERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3G1</accession>
    <name>A0A2G4F3G1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3685 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56286">
        <property type="protein sequence ID" value="PHX56286"/>
        <property type="gene ID" value="CP500_006195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022552">
        <property type="entry name" value="UPF_Ycf55"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12452">
        <property type="entry name" value="DUF3685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="362" mass="41179" checksum="38B203F23A279B38" modified="2018-01-31" version="1">MNSEFVVENTESSVIASDWQGSLFDSLRAKLQLDLVNLTGVPLEIDILRSTKKLELMSSILRKLEELLEELRLGQVQPTQLPEKIPTILRDLWEQTIIDFFGRYYTLQISRDQILDRIQADLKPSKSPAETSAFKFARNSIEVVPVLLEDTDSVRAEILDKIPMVVDLFTHFLFETPLIVDNISCLTGSPQAMQRAESLLHNLVIQVASGVVQPLLNNFANVEEIKQGFYDGKLISTREIERFRNNLSWKYRWESYFVEPKAIFESRFWLFVLTDYGIHRIFIYAPRNLELAQLSGWQLALTLVLEARDAISPRVRAVILLLGAGIVYILTEVIGRGIGLVGRGIIQGIGNSLQDTKFRKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3T9</accession>
    <name>A0A2G4F3T9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56391">
        <property type="protein sequence ID" value="PHX56391"/>
        <property type="gene ID" value="CP500_005610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="106"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="305" mass="34742" checksum="95839B34DDE63A84" modified="2018-01-31" version="1">MEVEKMLSLLDEWVLEKKGKSLDFAQKEIIRLSWLDVDYADMNISGYSPNYVERRLAQGLWALVSEVIGEGKKVTKKTSKLAMEEAIKKRSRPEAPAREMSFFDAARDANNRGLKLKQAGEFVAARKEFELALKINPDNAATYYNQALMYEEAGIVDRAMALYQDAAFRGFAAAYCKLGRLYIIEYKDLRKSVEKIGLGLKLVETEKVKHDKIVKAGLLTYLAWAWKEQGRYEEALVKLQDAVKLDSIRGLTYGIMAQVQENLGNHAEVVKAWKNCLEYGKCDRPDEDFYMGKARQRLKQIAGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F430</accession>
    <name>A0A2G4F430_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF262 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56520">
        <property type="protein sequence ID" value="PHX56520"/>
        <property type="gene ID" value="CP500_005040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="55"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="396" mass="47260" checksum="56B353D5951CE572" modified="2018-01-31" version="1">MITNSYLISGETYISQNRPDTTHNFPPDDEINEKYKKGEIRIVTEQARYPLDSIEAMLDSAKYIRNPEYQRRKRWNNTRKSRLIESFIMNVPIPPIFLYEIDYSIYEVMDGQQRLTAIYDFYKGKFELEGLEYWQELNGRNYQNLPEQVQKGIDRRYLSSIILLQETAKSKEEAEYLKQIVFERLNSGGEKLTAQETRNALHNGKFNRLCIKLSENDPFRKMWNLPLESEGEEKLLESESYRKMEDVELVLRFFAYRHIENLKSPVDKFLDEYLKQANNYSDQTIENLENIFQQTIQLIYSILGDSAFIPPKEQRDRKTPLKTIYDPIMQVFANNIPHKESLLRNKADIKSNLYSNKELLYIKEENNRSLFDGRYNNKKDVEARIEYFHNFLKNYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F452</accession>
    <name>A0A2G4F452_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56515">
        <property type="protein sequence ID" value="PHX56515"/>
        <property type="gene ID" value="CP500_005015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="84"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="19033" checksum="0FF4566637B577C2" modified="2018-01-31" version="1">MSFKKSIQSILLGFALCFCLLVGIGQNPILAATIIETKPIFQERMQTMSEKTVNLESAIDRFLTSIPPGYYTIANVEGLKNLLKNPQTLLVDVREPSEYRSGHIPNALNIPLQTLAHNLEQIPHDRPVVLYCSAGYRSAMGVMTLHLLGYENVQGFPPSFAGWKNAGEAIASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4E8</accession>
    <name>A0A2G4F4E8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56615">
        <property type="protein sequence ID" value="PHX56615"/>
        <property type="gene ID" value="CP500_004590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="33"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="301" mass="32946" checksum="E2CE6DC28ECAE1AB" modified="2018-01-31" version="1">MTSSTLTAVAPQTWLWKGFPICYQTAGTQGPAVVFVHGFGASWGHWRKNLPGLAADCRCYAIDLIGFGGSAKPAPKLEIDYTFETWGQLIADFCREVAGGSAFLVGNSIGCVAIMQAAVDFPDVASGVILLNCSLRLLHDRKRAKLPWYRSLGAPIAQKVLNVKWISQLFFKQLATPNTVRKVLLQAYHRPEAVTDELVNMLLEPAKDSGAVDVFVAFISYSQGPLPEDLLPRLSCPALILWGTDDPWEPIALGRELAKFPAVEKFIPLEGVGHCPQDEAPELVNPILLDWIKGRSAFTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4G8</accession>
    <name>A0A2G4F4G8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Group II intron reverse transcriptase/maturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ltrA</name>
        <name evidence="2" type="ORF">CP500_004290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56635">
        <property type="protein sequence ID" value="PHX56635"/>
        <property type="gene ID" value="CP500_004290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025960">
        <property type="entry name" value="RVT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13655">
        <property type="entry name" value="RVT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="86"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="574" mass="65711" checksum="306955EB29AF458F" modified="2018-01-31" version="1">MSKALEAEWSSMVWSEIQAKLTKLQTKIYEASKSGNKPLVVKLQKTLISSFSARLIAVRRVTQENKGKRTAGIDGIKSLTPQQRVGLAEQLRLDGKSSPLKRVEIPKPGKKEKRPLGIPTIEDRAKQALAKLALEPEWEALFEPNSYGFRPGRSCHDAIEAIELSIRKKPKYLIDADLKGCFDNIDHEALIQKLKTFPDMEKQIRAWLKSGVLVGDVFHKTVSGTPQGGVISPLLANIALHGFESYISSEFPQRKTRIGQPTGKMKEYCDAKVIRYADDFVIFHEEEEVIKAALEKTRQWMANIGLSLNEQKTRLCHTLEDYEGEKPGFNFLGFQIQSFSRGKNRAGKKTNGESLEMVTKVLPSDESIKQFQSHLKALLNKGQSQEPTRMIESLNWFIRGWGNYFKSGSHSHEVFSKVQHSLYKVYLNWGRKKFSQKGDGYICSRIFFKSKESSWNFGWKEGDRLYLVEMLYSFEYKHYIKVQGTRSPYDGDWVYWATRRGDHPLTPKDIRFGLKNQKGRCSHCQQLFTIEDYIEVHHIDGNRNNNKKSNKTLVHLYCHDAIHLENAGSITDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4I2</accession>
    <name>A0A2G4F4I2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56659">
        <property type="protein sequence ID" value="PHX56659"/>
        <property type="gene ID" value="CP500_004345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="171" mass="19426" checksum="457C61DAF89E1069" modified="2018-01-31" version="1">MESPQILQFVDEAVCARTGKHLNNLQRKIIAGILKRQRYADVAETYAYSSQHVKKASHELLQMLSEVFGEQVKKSNLESVLERHINQNITTLGNKNTQKIIGINYINNCPNPSTPTPDESQPETPDLQEETKNQTKIETIDKLRQFGLSDEQIAEALDIPLEQVKQVDLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4L7</accession>
    <name>A0A2G4F4L7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56733">
        <property type="protein sequence ID" value="PHX56733"/>
        <property type="gene ID" value="CP500_003740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="20"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="168" mass="19911" checksum="38F7601843E8E96D" modified="2018-01-31" version="1">MGLYRSNPCNHQVRLVSVLWGKTWYYYLTNVKNPQKLSARQVCELYRRRWRVEEAFLLTKRLLGLSYLWVGGNNGVEIQVYATWIFYAVINDLCSSVAVELGQPKERISVEMVFRGLYHFSHYLLRGKMTDAVTYLVEHHKMLGLIKQERKRHRDNAAIEREIWESTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4S7</accession>
    <name>A0A2G4F4S7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56711">
        <property type="protein sequence ID" value="PHX56711"/>
        <property type="gene ID" value="CP500_003595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020948">
        <property type="entry name" value="P_starv_induced_PsiE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06146">
        <property type="entry name" value="PsiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="152" mass="17140" checksum="C87A7C9C01598684" modified="2018-01-31" version="1">MLKKIFRQLSKFGSDEQFLNFTESVEVVVSKVLSLAMIFVIIFSVCDLLIFLTKELINDHQTLFKDTLFVIFGLFLNVLIALEILENITAYLKKHVIQVELVIVTSLIAVSRKIIILDLEKKTAADLIGLAAAIFALSISYLIVRYSNKGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4T7</accession>
    <name>A0A2G4F4T7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56721">
        <property type="protein sequence ID" value="PHX56721"/>
        <property type="gene ID" value="CP500_003670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="334" mass="34255" checksum="B2DEAFD4BBC8A959" modified="2018-01-31" version="1">MSQLFPNPKSINPLAQPPENPAAPGNPPRPNPGAPGNPPRPNPDTPGNPPRPNPDTQLTSSALPPQNQTPPPPPANSINTTAGNDNITGDSFENFFVASIGTDSINGGLGTDTISYLSLGSGITLKAQGLVSKGAAGNDTLQSIENIIAPLGQINTIDASTGSGTASINVDLSQNQLAVNNIPTIGTLNFTVENFVNVTGTPNVDVLTGNIENNTLVGGDGNDTLSGLAGNDTLIGVNPLSATPGINETDTLIGGQGRDIFVLGDATKTYYSGTGFALIQDFELGIDRIQLRGSLSNYNIVGNSINLAGTSDQIAVLQPGLNAQNLTPDNFLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Y1</accession>
    <name>A0A2G4F4Y1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56806">
        <property type="protein sequence ID" value="PHX56806"/>
        <property type="gene ID" value="CP500_003520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11476" checksum="C614318F3BA75151" modified="2018-01-31" version="1">MKIWIDAQLPPTLANWLTETFGLEASALRDLALRDAQDIEIFEAARAENVAIMTKDSDFIDLVCRLGSPPQILWLTCGNVTNRNLRQLLTAILPDALEQLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Z2</accession>
    <name>A0A2G4F4Z2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar assembly protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56820">
        <property type="protein sequence ID" value="PHX56820"/>
        <property type="gene ID" value="CP500_003200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="398" mass="44718" checksum="374EAA21B473E22B" modified="2018-01-31" version="1">MTRFIHDRFAKEYLEELLSPIGTVNIGRDVTSEVREIDVYFTPITLNPEYLKTLGLLGKIASTTAIIEPFRNPANVSEICSCLGKLLDVRGELERQSRRENTRLDDSQLPKLWILMPTASKALVDSFNAKPDTENWMEGIYFFGESLRTAIVAIHQLPETPETLWLRILGKGKVQQRAIAQLSALPTDDPLRMIALELLYRLQSNLVTDIPQELEPEERELIMAIAPLFQQQIEAAQQKAREEGLERGLEQGLERGLERGLERGLEQGLERGLEQGLERGRQEQQRLILESFLQVRFGELIPKMMVVLAPISKLSATDFTVLLLAISMLKVDESGRESAVKLLAESVLKMSSNELGDLLPIAVTNLLGLSVAELALFVEQLPQLSADELRERLGKTPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F570</accession>
    <name>A0A2G4F570_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56934">
        <property type="protein sequence ID" value="PHX56934"/>
        <property type="gene ID" value="CP500_002855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="169" mass="19622" checksum="10F61B2A154A38DA" modified="2018-01-31" version="1">MKVRNYEISDTQKIIQLFYDTVHQVNIRDYTKAQVDAWAPADIDIEIWMKSLSSKFTFVAEDGGIIAGFGELETNGHIDRFYCHKDFQRKGVGTQILEHIESQAKDLGMNRLFTEASITAKPFFETHKFIAIKKQEVERRGQKFINFAMEKNLENIFIGRSYIAILNHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F582</accession>
    <name>A0A2G4F582_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YggT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YggT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56906">
        <property type="protein sequence ID" value="PHX56906"/>
        <property type="gene ID" value="CP500_002700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="PTHR33219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="YGGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10847" checksum="8B7FB4BD3AA7DD85" modified="2018-01-31" version="1">MTYSIGLLATTLSSFLQIYLYLMIFRVLLTWFPNIDWSSAPFSILSQLTDPYLNLFRSIIPPLGGIDFSPLIAFFVLQFGSEFLINLLNNLQTAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5F6</accession>
    <name>A0A2G4F5F6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Adenylate/guanylate cyclase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_003575</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56707">
        <property type="protein sequence ID" value="PHX56707"/>
        <property type="gene ID" value="CP500_003575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="440"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="7">
        <location>
            <begin position="532"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="721" mass="81295" checksum="2661FE1D9216F6E3" modified="2018-01-31" version="1">MRSLNQLNRFSVGTKLIVMLLLVSLCSMLASTFICSRAGQQLLEQRVFNQLTSLRSIRTEQIEQYFKFLVHHTQTLSDDDMFINAMKEYKQAFDELATVNLPKAYDDKLDQFYRNEFVPRLKKTVDAAPLPETFLPKNAASRYLQYHYIANNPYPIGEKYKLEDPKDGSNYTRVNLRYNPKFVNIAQRFGYYDTYLIDLNGNVVYLLSNQGDLGTNLFAGPVADSNFVQGLKDARRSNSKAYVKIVDFQPYIYSYNGPSAFIASPIFDGSQMIGVLAFQIPADRLSDIVNGYGKWKENGLGDTGETYLVGQDGMMRSKSRFLIEDREKFTKSLSESGLPESSVKKIRDIDTTILFLPANVDGVKQALFGKSVLLRDKDYRGSEVLGAYAPVEVDGLRWAIAAEIEISEAFAPISTFQREVVIAAALIVIIVTLVAMWLARLFVKPIDRLIASTQKVESGDGKTMVTSGTRDEFADLARSFNEKVYALRSHIREVEQQNTENQGLIDLLLPAKIAKRIKQGEGVIADPFSNVSIIFTDLHRFSKLFESLSAQEVVFLLDELVDAFDDFADKHGLEKIKTIGDGYMAVCGLSVSRLDSDKRTINCALEMLAHVRRFNYERGLNLDLRIGINTGDLISGIVGKSRYVYDVWGETVNIAHRLKSCCPPGSILVSELVRDRLADLYEFDRVEIVEALDKEPLKAWELRTNHPEAIVKPQNETEGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5R5</accession>
    <name>A0A2G4F5R5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplR</name>
        <name evidence="7" type="synonym">rpl18</name>
        <name evidence="8" type="ORF">CP500_001740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57143">
        <property type="protein sequence ID" value="PHX57143"/>
        <property type="gene ID" value="CP500_001740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="120" mass="13352" checksum="84D8B0E58CBAB872" modified="2018-01-31" version="1">MKLTRKESVHRRHRRVRRKVFGTSERPRLAVFRSHQHIYAQVIDDMTQHTLVAASTLDPELKSELSSGGNCNASVQVGQLIAKRCSSAGIVKVVFDRGGNLYHGRVKALADAAREAGLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5V4</accession>
    <name>A0A2G4F5V4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplF</name>
        <name evidence="3" type="synonym">rpl6</name>
        <name evidence="7" type="ORF">CP500_001745</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57173">
        <property type="protein sequence ID" value="PHX57173"/>
        <property type="gene ID" value="CP500_001745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002358">
        <property type="entry name" value="Ribosomal_L6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00525">
        <property type="entry name" value="RIBOSOMAL_L6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="11"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="90"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="182" mass="19707" checksum="0A8D166598473772" modified="2018-01-31" version="1">MSRIGKRPISIPTKVTITLDGQKVAVKGPKGELSRVIPAEILMGLEGETLLVTRRDESRVARQLHGLCRTLVANMVEGVSQGFQRRLEIIGTGYRAQVQGRNLILNVGYSKPVEMPPPEGITVAVEGNTNVIVSGIDKELVGNTAARIRAVRPPEVYKGKGIRYSGEVVRRKAGKTGKTGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5W9</accession>
    <name>A0A2G4F5W9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57091">
        <property type="protein sequence ID" value="PHX57091"/>
        <property type="gene ID" value="CP500_002085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009387">
        <property type="entry name" value="HigB-2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06296">
        <property type="entry name" value="RelE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="14301" checksum="382ADB76E386E971" modified="2018-01-31" version="1">MMSEQPLIQVEAAPTFTKNLRSLAKKYRSIRDDIQPIIEQLERGELPGDQISGIGYDVFKLRVRNSDIQKGKSGGYRMIYYVKTTNGIILLTVYTKSEQADIPADEIIGIIVEYERHTVEYEEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F609</accession>
    <name>A0A2G4F609_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57196">
        <property type="protein sequence ID" value="PHX57196"/>
        <property type="gene ID" value="CP500_001345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="26"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="22430" checksum="CA6B0D228D1A00BF" modified="2018-01-31" version="1">MVTLIQHPAPTQLETPAEEKVWTDAEFMALNRDGHRYEIVNGELIDMGNSGAKHGYVCSVLMILLGGYVHIQKLGAMFDSSTAFKMKSGNKRSPDLSFMAKERLQGLDELPDGFLEGAPDLAVEILSPSNTVEEIHNKLVEYFDNGSRLVWVINPKEKYVLVYRSSQEPDRLLKSIDSLDGEEIVPGFTLPIGDLFQKLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F654</accession>
    <name>A0A2G4F654_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57252">
        <property type="protein sequence ID" value="PHX57252"/>
        <property type="gene ID" value="CP500_001015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="193"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="44328" checksum="D981C92DADB34C64" modified="2018-01-31" version="1">MRILVVSHTYIVDINRQKFKILANLEPGIEVTIVVPQRWKPGGVQNKIIETQFCQSGSFKVVPISNFSQNNQGLLTFGTDIIKLLHEFRPQIIQVEQGSKSLAYAQLILLNKLLKLKAKNILFTWWNLSYELKWPVSFLEDCNLKHTDGIITGNLDGAEILRQRGYQNTLKVMPQLGVDETLFYRTSKDADLSRKFGIQPTDFVVGYVGRFVEEKGLLTLAKALAGFKKLPWKWLLVGQGKLRSQIAEKSIEWGISDRIIWVESVSHEDVPPYINLMDCLVLPSQTSYKFKTLTTVGWKEQFGHVLIEAMACKIPVIGSDCGEIPHVIGDAGLIFPEGNAEKLRECLDELMERPELVADFGKRGYHRVMNNYTNKALAEQLLEFYKELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F666</accession>
    <name>A0A2G4F666_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57283">
        <property type="protein sequence ID" value="PHX57283"/>
        <property type="gene ID" value="CP500_001190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8640" checksum="C097F8AFEB5D78C4" modified="2018-01-31" version="1">MKTQELRQNLKQSIDSLSPERLLVVADFLAYLAERESNEATNELLKIPGFLEAFNKARTDVAAGKVTTVEQLKRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6B5</accession>
    <name>A0A2G4F6B5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57312">
        <property type="protein sequence ID" value="PHX57312"/>
        <property type="gene ID" value="CP500_000585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013841479" evidence="1">
        <location>
            <begin position="39"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="21146" checksum="0B11AC4A8ECE2D3F" modified="2018-01-31" version="1">MRFNQFSSQQFSRILAAGLTAVATITAICATILPNAQAQVPSGRYQIQSNNQIFFYPANGTDPVVVYNGKAKAVAITQYGSAVYTAFEGGKIYRSPDGQGLGGSGKTTLIYSGSQTVRAMLSCQGALFVAYSGGYIYRSPDGQGLDGSLRTQNVYKGSVKVNKMTCDGDRVVTSFENGKVYLSPDGLNLGGGGKTTNLSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6B9</accession>
    <name>A0A2G4F6B9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molybdenum cofactor biosynthesis protein MoeB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_001090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57265">
        <property type="protein sequence ID" value="PHX57265"/>
        <property type="gene ID" value="CP500_001090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="296"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="42740" checksum="25D7D16488F63367" modified="2018-01-31" version="1">MLNPNLDEIQLNKEEYERYSRHLILPEVGLDGQKRLKAASVLCIGTGGLGSPLLLYLAAAGIGRIGIVDDDVVDHSNLQRQVIHGTSWVGKPKIESAKNRILEINPFCQVDLYETRISSENAIAITTPYDIVIDGTDNFPTRYLMNDVCVLLNKPNVYGSIFRFEGQATVFNYEGGPNYRDLYPEPPPPGMVPSCAEGGVLGVLCGIIGTIQATEAIKIILGQGTTLSGRLLLYNALDMTFRQLKLRPNPVRPVIEKLVDYEQFCGIPQAKAQEANQQMQIPEMTVTELKELIDSGAKDFVLLDVRNPNEYQIAQIPGSVLVPLPDIENGNGIEKVKELLNGHRLIAHCKMGGRSAKALGILKEAGIEGINVKGGITAWSQEVDPLVPQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6H4</accession>
    <name>A0A2G4F6H4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57356">
        <property type="protein sequence ID" value="PHX57356"/>
        <property type="gene ID" value="CP500_000825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039018">
        <property type="entry name" value="VapC20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42188">
        <property type="entry name" value="PTHR42188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="15983" checksum="1AEDF8499A90A683" modified="2018-01-31" version="1">MRKVFADTGYWIALLNPDDALHQKARNLTISLKNVPIVTSEMVFTELLNAFSGRGAFYRQKAVNFINHSFDNPEIEVVSQTNELFKNALELYNSRLDQAWSHTDCTSFQIMQQQNILEALAYDKHFEQAGFVALLRIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6I1</accession>
    <name>A0A2G4F6I1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57349">
        <property type="protein sequence ID" value="PHX57349"/>
        <property type="gene ID" value="CP500_000790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="169"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="488" mass="54775" checksum="28D168667ED205A5" modified="2018-01-31" version="1">MDVEEALKFTDNLALTTTGKHLDSLQKAILRGAWNNQKYKEIAQHHNRSEKYVKEVGFKLWKLLSVALGEEQVSKANFRAKLENLQASNIISLVGNGCIHIGNISADSSQPSKKLQSEPQDKDKFNEKTSNSEPKIHLDLGDAPEPNLFYNRTSELTTLQNWILARTRLITILGLSGIGKTALTLQLIPQIKHEFDRIIWRTLRNAPPLASLQTDLIKSLSQQQETNPPNPPLSRGGEEIKPPSLSPPLSKGGLGGVIHHLRSYRCLIILDDIQTIFSSQQLAGNYQPGYENYGTFFKQIAESSHNSCLMLLSWEKPREIAALEGENRPCKSLQLNGLGPEAQEIFREKGLAEPDKWSELIDLYRGNPLWLNIISTLIQDLFGGSVSEFLSYDTLFLGDLESLLEQQCDDRLTASEQQVMGWLASTSEPADISKIPENLQLSPPELLKVIQSLGRRSLVETVKQNGRSHFTILPVIREYIINKTRNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6K0</accession>
    <name>A0A2G4F6K0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome maturation factor RimP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rimP</name>
        <name evidence="5" type="ORF">CP500_000035</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of 30S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RimP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57369">
        <property type="protein sequence ID" value="PHX57369"/>
        <property type="gene ID" value="CP500_000035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01734">
        <property type="entry name" value="YlxS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01077">
        <property type="entry name" value="RimP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003728">
        <property type="entry name" value="Ribosome_maturation_RimP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028998">
        <property type="entry name" value="RimP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036847">
        <property type="entry name" value="RimP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028989">
        <property type="entry name" value="RimP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035956">
        <property type="entry name" value="RimP_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33867">
        <property type="entry name" value="PTHR33867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02576">
        <property type="entry name" value="DUF150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74942">
        <property type="entry name" value="SSF74942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75420">
        <property type="entry name" value="SSF75420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="DUF150" evidence="4">
        <location>
            <begin position="13"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17336" checksum="4018D00A41131295" modified="2018-01-31" version="1">MTHPLIPQIIDLATPVAETLGLEVVGAVFHTHYNPPVLRIDIRNRQEDTGLADCERMSTALEAELDVADIIPDAYVLEISSPGISRLLSSDREFITFKGFPVTVKAAEPDSRIKEWKGLLVSRDETTVYLNQKGRQIKIPRLQIAKVELDEGKEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6K6</accession>
    <name>A0A2G4F6K6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57424">
        <property type="protein sequence ID" value="PHX57424"/>
        <property type="gene ID" value="CP500_000360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="182"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="216"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="250"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="284"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="318"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="411"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="452"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="486"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="552" mass="62284" checksum="769CC13A61295473" modified="2018-01-31" version="1">MNNSLQVHEETASNYFHRGNLLKQSGKLEEAAAAYQRCTELNPDFSWYHHNLGEVLAKLGQRDGAEKSYRRACELNPNSAWSWHNLGEVLEQQGNLDEAVAAYRKAVEIYPDFYEFYNSLGQALCLQGQLDESVSCLRHAIALDSESALPYQNLWEALARLGRVDEGMDCLRRAIELNPGEGDLYLKLAEALQGKNEFAEAVGYYRKAIQLKPDFHWIYYKLGTALSAQGQWEEAIASYSKAAELEPGSAIVHHYLGHTLSIVQRWDEAIASYRKALDIVPDAAVIYQHLGDALTRLGRWEQAVGAYRKSVEFEPNSLEAQDHLGFALYQLGRYDEAIATYRKALDVAPNSDVVSFHLGDALRQRARVQPLQKDIDADLDAAVNCYRRSIELNPNNLEVCQKALEIKPDEPELYLQFGKALALQNQLEGAIVQYKKAIELDANNIKLDGKNGDTYRYLGDALAKLGRWDDAIDAYKRLLKINPDDFMCYEGLGDVWLGKGMVERAIEFYQKAIELNPDLAEVYDKLGDSLAKVGRQKEASVSYRRGLEVKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6R2</accession>
    <name>A0A2G4F6R2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Colanic acid biosynthesis glycosyltransferase WcaI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57405">
        <property type="protein sequence ID" value="PHX57405"/>
        <property type="gene ID" value="CP500_000245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="216"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="422" mass="46643" checksum="7379609AF02F8132" modified="2018-01-31" version="1">MRILIYSYNYYPEPIGIAPLMTELAQGLVKRGHQVRVVTGMPNYPQRRIYEQYRGKFYLTEKHKGVTIQRSYLRVNGPHPSFLDRLLLDGSFVISSAVQAFRGDRPDVIFSTMPPLPICVPVALYGWIRSCPIVLNVQDIVSEAAVRVGLVKKNGILIRIADALEKFAYSTASKVSVIDSGFVQKLHSQGIPPEKIVCLPNWVDVNFIRPLPKENNSFRKTHNLQGKFVILYAGNIALTQGLQTVVQAAARLKHIPEIAFVIVGESTALGRLQKDCETYKATNVMLLPFEPREKLPEMLAAADVSLVVQKRRVTDFNMPSKIQVLLASGRAILASVPETGTAHKAVQQSGGGVVVTPEDPQALADGVEDLYLNPAKLEALGLQGRSYAVENYGFEEALNHYEALFTVVTARGGEKILEPLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6X4</accession>
    <name>A0A2G4F6X4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57327">
        <property type="protein sequence ID" value="PHX57327"/>
        <property type="gene ID" value="CP500_000675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="98" mass="11204" checksum="381765570076C5DE" modified="2018-01-31" version="1">MLTLDIQSILNSIPNEISWQDIVQFEKLDDRVSIANDLCANIIGVNESTIEWCPNEDSADRLEQLVWWWVVHPDLGAAIAKEAPQELKNIISQYILQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUG6</accession>
    <name>A0A2G4EUG6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NblA-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000252">
        <property type="protein sequence ID" value="PHX53175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53175">
        <property type="protein sequence ID" value="PHX53175"/>
        <property type="gene ID" value="CP500_022900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007574">
        <property type="entry name" value="NblA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036904">
        <property type="entry name" value="NblA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04485">
        <property type="entry name" value="NblA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109859">
        <property type="entry name" value="SSF109859"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7832" checksum="86867ECC9B8013D3" modified="2018-01-31" version="1">MNQPAELSLEQQFSLCSFKTQVSDMSREQAQEFLVKLYEQMMLRETMYRHFLKHHWGLEPNPALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUG8</accession>
    <name>A0A2G4EUG8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000246">
        <property type="protein sequence ID" value="PHX53192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53192">
        <property type="protein sequence ID" value="PHX53192"/>
        <property type="gene ID" value="CP500_022770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="158" mass="17110" checksum="0421C77FF3A1B3C7" modified="2018-01-31" version="1">MTNSYEITPEPKITIVIPVYNGARYLATAIASVLGQTRKDFELLISDDGSTDSSVEIALSYAQKDSRVRVITADHQGSAIALRTGFAEAKGIYIGQLDSDDILDWRALELTVPILDAHPEVGIVYTDYLDINQNGQILGLGQRCSIPHSAPPTGTYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUR6</accession>
    <name>A0A2G4EUR6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-L-glutamate ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000223">
        <property type="protein sequence ID" value="PHX53283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53283">
        <property type="protein sequence ID" value="PHX53283"/>
        <property type="gene ID" value="CP500_022335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="77"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="280" mass="32568" checksum="7F82072EC140BA51" modified="2018-01-31" version="1">MLTNISLVLEACQELNINYEILAPNQNLIRIQHSDQDYYFVNYITPFNSAPIVQIFKDKEYTYQLLNTKIKTPKTVGFLSPFCDSKYREYLKIKKCEEIADEVSKIFFLPLIIKRNRGSAGNNVFLCETHEQIQSAIETVFNVNSKDYDYICLAQEYINIRHEYRAVFFNKKLVLLYEKDKSGAKFMGNLSPLHWEGATAKHIKDSKIVSEIESFVQPVFAEIHVTYGGFDIAIDQNGDYWLIEINSSPNYDIFVRDNDRQIVVTMFKHILETLVVNKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUT2</accession>
    <name>A0A2G4EUT2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate/guanylate cyclase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000222">
        <property type="protein sequence ID" value="PHX53291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53291">
        <property type="protein sequence ID" value="PHX53291"/>
        <property type="gene ID" value="CP500_022295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007890">
        <property type="entry name" value="CHASE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05226">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01080">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="458"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="651" mass="71869" checksum="91481FD5422EE656" modified="2018-01-31" version="1">MPKLLHQFHHHLNGKDWSWQNLTQSLPLAELKPLMIACIAVTGTILGVRHLGWLQPLELKAFDVMVQLRPDAVADPRLLVVTITEQDINTIGKWPISDRTLAKAIAEIASLEPTAIGIDLIRNTPYEPGNAELVTQLKNPKVIPITLIGNSKQDPAPPPPNIPEDRVGFNDIVVDPDGIVRRNLMFAGNGNKTLTSFSMRLAFAYLDSKKVDSKLTDTQEIQANKVVFSKLRSDSGGYQRISDRGYQILLNYRSAENIAKSVTLTQVLEHKVDPKLVKGKIVLMGVTALSVKDFFPTPYTATASGNRPMAGVFIHATATSQILSAVLDGKGLFWYWEEWQEILWIVVWGAVGGWLAWRLQNSLILIGSAIAAFGLLLGCTFFLFTQQGWIPLIPAAVALLITPGVIVTYKYQESRQQQEIVMKLLGQQTSPAIANALWKERVHLLESGLLPGKKLTATIILTDLQGFSTISEKLPPEIVMSWLNEYLSAMAEELQAHQGVINKFTGDGMLAVFGVPIPRTTPAEIAEDARLAVSCALAISSRLPQMNQNWRDRGLPAARMRVGIFTGPVMVGSLGGTTRLEYGVIGDSVNIASRLESCEKDRQEDTCRILIAEETLQHLADRFAVESWGALPLKGREQKVNVYRILGMKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUX4</accession>
    <name>A0A2G4EUX4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_022310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000222">
        <property type="protein sequence ID" value="PHX53288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53288">
        <property type="protein sequence ID" value="PHX53288"/>
        <property type="gene ID" value="CP500_022310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="33"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="12145" checksum="272BC42848D73C4C" modified="2018-01-31" version="1">MSNSVIVISDEKFETEVLQAEQPVLAYFWAPWCGPCKLVSPSIDWIAAHYSDRLKVVKMEIDPNPATVKQYKVEGVPAIMLFKNSELVMSYEGAITKQKLTVLLEANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUX5</accession>
    <name>A0A2G4EUX5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CHASE2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_022030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53334">
        <property type="protein sequence ID" value="PHX53334"/>
        <property type="gene ID" value="CP500_022030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007890">
        <property type="entry name" value="CHASE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05226">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01080">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE2" evidence="3">
        <location>
            <begin position="49"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="615" mass="68775" checksum="240E39A2A06CA717" modified="2018-01-31" version="1">MSKIFNQIRSAKAQLSQLYKPSVAFARSVLIATAAVTLSLMGARQLGILESVELNAYDQMVRLRPDESPDSRLLIVGITESDIQRLKQWPISDRKIAEILQKLEKLQPRVIGLDVLRDVPLGEGREELTKVLSRSDRTIGVCLVTDGSADSPGSPPPPGIPKDRIGFADFGVDQGGVVRRALLFMKPPTIEGNLVAEKHLCNDNSQVLFSFNLQLALRYLKPEKIYPKLASDKSLWLGKTQFKQLSANDGGYKNVDVRGYQILINYRARKKVANQVKLMDILEGKIDPNLVKDKIVMIGYTSETVKDFFYTPYSAGKNENQFMPGIVTHAQVVSQILSGVLDNRPLFWFWPKWVEILWISGWSIVGGTLAWRMTHPTRLTLTFLAMLGVCFIICFGIFLLGGWVPVAAPALALIATGGSIVSADRFNKSGYGKVISAQIKQVFKVEIDQAKKDEEVAEITQSQFFKDLQKKKDQFKASKKEISAKEPLPATEIIVGSTELQNTESQPDDYLNQLQQKAQQQKRRPPLTEAEKDSQNAVNVEGLKNDSGSETESEKNSENALIVDKKNNDSAMETEADGELTYLQAKARDMRSRKSAKNRIKEQKNQDLEDKERKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVA7</accession>
    <name>A0A2G4EVA7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">galE</name>
        <name evidence="10" type="ORF">CP500_021620</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="NXIB02000201">
        <property type="protein sequence ID" value="PHX53418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53418">
        <property type="protein sequence ID" value="PHX53418"/>
        <property type="gene ID" value="CP500_021620"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="9">
        <location>
            <begin position="8"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="332" mass="36313" checksum="90144810FE4B7936" modified="2018-01-31" version="1">MSADKETILVTGGAGYIGSHAVLALKRAGYNVLILDNLVYGHRDLVEQTLQVEFVVGDTSDRVLLDKIFATHNIAAVMHFSAYAYVGESVTDPAKYYRNNVIGTITLLEAMIAAGVKKFVFSSTCATYGVPQRIPLTEDHPQNPINPYGATKLMVERILSDFDTAYNFKSVCFRYFNAAGADPSGLLGEDHNPETHLIPLVLLTALGKRDSIAIFGTDYDTPDGTCIRDYIHVNDLASAHILGVEYLLNGGKSDFFNLGNGGGFSVKEVIEAARTVTGKQIKAIECDRRPGDPPALVGSSKKAIETLGWSPEYPHINDIISHAWQWHKKRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVB3</accession>
    <name>A0A2G4EVB3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thiol:disulfide interchange protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_021350</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000193">
        <property type="protein sequence ID" value="PHX53471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53471">
        <property type="protein sequence ID" value="PHX53471"/>
        <property type="gene ID" value="CP500_021350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044241">
        <property type="entry name" value="TxlA/HCF164"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47353">
        <property type="entry name" value="PTHR47353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="44"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="21491" checksum="70AC51B7D094B1A7" modified="2018-01-31" version="1">MSPNSPNSTTVATPQKLETNSAATRIRNLLIVLAAIALSVSIFFGLRTQTPSSSLTAMAKASAPLETALANGKPTLMEFYANWCGSCQAMANDLSEIKQKYAEPLNFVMLNVDNDKWLPEITKYRVDGIPHFVYLNNKGSAVAETIGEAPRTIMEANLEALIAGKELPHAQATGQVSNFTPATGPVKTSSSDPRAHGSQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVE0</accession>
    <name>A0A2G4EVE0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phycocyanin alpha phycocyanobilin lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000186">
        <property type="protein sequence ID" value="PHX53512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53512">
        <property type="protein sequence ID" value="PHX53512"/>
        <property type="gene ID" value="CP500_021125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="217" mass="23406" checksum="F3DBC11842D0AD74" modified="2018-01-31" version="1">MSITPESVEQLLNSEDFGDRLRGVNQLRQLEPAIAYKLIQSAIGDKNVRVRYAAVSQMSTLGTENLSNALEVLIHSLNNDPEPDVQAAAADALGALKLTDALADLQQVYNNTSEWLVQLSIVAALGEMGDPKAFPMLENALTSDNELIQTIAISALGELGDKRALPLLLPYAGNVDWQIRYRVAQALRRLGGAEAEAALEILTKDEVEQVAVEAKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVQ7</accession>
    <name>A0A2G4EVQ7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000184">
        <property type="protein sequence ID" value="PHX53520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53520">
        <property type="protein sequence ID" value="PHX53520"/>
        <property type="gene ID" value="CP500_021050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032171">
        <property type="entry name" value="COR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020859">
        <property type="entry name" value="ROC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16095">
        <property type="entry name" value="COR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51424">
        <property type="entry name" value="ROC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Roc" evidence="4">
        <location>
            <begin position="294"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="959" mass="109512" checksum="A116AE5993265AB2" modified="2018-01-31" version="1">MTREEALRRIDIAAAEPLTQLDLTELGLEELPPEIGKLSNLTQLNLSNNQITEIPEVVGKLSNLTELDLSNNQITEIPEVVGKLLNLTLLDLSYNQITKIPEVVGKLLNLTLLYLSNNQITEIPEVVGKLSXSNLTGLALSNNQITEIPEVVGKLSNLTQLDLSNNQITEIPEVVGKLSNLTQLDLWNNQITEIPEVVGKLSNLTGLALSNNQITEIPEAVGKLSNLTRLDLSNNQITEIPEVVGKMEKLEKLDLRGNPIPIPPEILGEKELYKSPGDLRTILDFYFQTRDPDATEELNEAKLLIVGEGEAGKTTLANKLLNPNYELKEREPATEGIDVMRWEFPQPNGKPFRVHLWDFGGQEIYHATHQFFLTERSLYVLLVDNRRQNPNLCYWLSIIELLSDGSPVFLVQNEKQDIRCEINLSQQRRDFPNLEKDFATNLATNRGLEALQRALQNRITTLDHINTPIPKRWANVRYVLENYSQRQTHIEVGEFFNICVSQGFKKSDKTAMLSLSKYLHELGIILHFQKDPILKNVVILRPELATKAVYKVVGNKKVTENGEVTDNAEVIANYGYFTQENLKQIWRDRQYQDLHDELLHLMKHFKLCYEIPSQPGKYIAPQLLPLETPHYTWDDTDNLILRYKYDFMPKGIITRFIVEMHLLIYRPQSDLPKGKGDIVWRDGVILADNYAKAEVIENYHQREIRIRVSGNQKKSLLDRIRHELWKIHATYDDRLKYQELIPCNCERCQGRQDPHLYDFEDLRRRLANNHYEAECGKTYKMVQVRRLMADFPDNLQQWEEKERLSGINQLDSGDTSSIQFNFNFDGKKMTETSSTTNNFNAPISGVAGSDNEVKNNQFNQINNANTAEIFKLISSMRETATQFPEDIRKEIITDIEDVEAEIKKPENERNPTRLKKRLTAMIAVATAIGVGIAGVTDFANTAIDVGNKLGIEIQLPPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW27</accession>
    <name>A0A2G4EW27_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53733">
        <property type="protein sequence ID" value="PHX53733"/>
        <property type="gene ID" value="CP500_019930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="12"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8498" checksum="181DB3548A7CBA77" modified="2018-01-31" version="1">MLPWLTQRLLRGEQRGQISLIKRLLQRQLGELNQEIEDNLFRLSSEQLSALGEALFDLSSLADLSSWLETNCPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW29</accession>
    <name>A0A2G4EW29_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_019915</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53731">
        <property type="protein sequence ID" value="PHX53731"/>
        <property type="gene ID" value="CP500_019915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="21"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="312"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="406" mass="42441" checksum="23201282F079B62B" modified="2018-01-31" version="1">MNFIESVKMAGQTLVANKTRSSLTMIGMIVGNASVIAMIGVGEGAQKFVAGQVQSLGTNVLIVRAGVPNARRGGLGNTPQTLVLPDAKAIATQVPSVQGVSAELNSSEIVRYSNKNVSALIFGTIPEFLQVRSFEMAKGRFLTDIDVKQSNQVVVLGSELAEKLFGNTNPLGEQIRIKNVSLKVIGVLAPKGTSFGTNYDNSAAVPIATMANRIVGRKSPYGLAVTSIFISIKDESKMDAAQFQVENLLRLRHKITTEDDFTVRNQKDLMATMGAISGSLSILLTAVASISLLVGGIGIMNIMLVSVSERTQEIGLRKAIGASQQDILFQFIVEAVILSAAGGLVGTFVGVSGILLIGNFTPLQAGISPMAIALAVSVSGGVGLCFGVIPARQAAKLDPIAALRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW64</accession>
    <name>A0A2G4EW64_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53773">
        <property type="protein sequence ID" value="PHX53773"/>
        <property type="gene ID" value="CP500_019685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="6532" checksum="D90024FF33A6393A" modified="2018-01-31" version="1">MKLTPTPKNDQASDAWTQADSAAPATALRLYSLHEQVAKVERASVGWTGRECKTIEMSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW97</accession>
    <name>A0A2G4EW97_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NYN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000195">
        <property type="protein sequence ID" value="PHX53457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53457">
        <property type="protein sequence ID" value="PHX53457"/>
        <property type="gene ID" value="CP500_021420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="117"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="275" mass="30532" checksum="3C54EC9F90B842BC" modified="2018-01-31" version="1">MLAIPLSLCCGLSVINRRRFEEVLQQRLATATAEIAAVSTRENRLDAIAIGSIQERILTLEKAQLQQQITQLQQWVTDLDDRLEELGDRDLELKQVQQQLAALQKSTSAPTKKGRGRVAIFIDGANLFYAIQELGIRIDYTKLLALLVGKDTLFRAVYYTGAEAADEKQRGFFLWLRHHGFRVVSKPVLQRPDGSKKANLDVEMAMDIVSLAGQYDTVVLVSGDGDLACALHQVSAQSARVEVVSLRSMTSDALIDVADSYVNLEDIQDKVCKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWA5</accession>
    <name>A0A2G4EWA5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">UMP pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_019505</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53814">
        <property type="protein sequence ID" value="PHX53814"/>
        <property type="gene ID" value="CP500_019505"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006223">
        <property type="term" value="P:uracil salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005765">
        <property type="entry name" value="Ura_phspho_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01091">
        <property type="entry name" value="upp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="216" mass="23533" checksum="3265B3EE056761D0" modified="2018-01-31" version="1">MSLQLRVYVPPHPLIKHWLAVARDSGTPSVLFRSAMTELGRWLAYEAIRDWLPTVETTIQTPLAECPATFINPEAPLCVIPILRAGLALLEGIQTVVPLASVYHLGIARNEETLEPTCYLNKLPAQFNPETRVIISEPMLATGGTIMATMQELTSRGVDPSLVRIISVVVAPAALKRLSAEYPTLNIYTATIDEVVNEQGFIVPGLGDAGDRTYGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWE5</accession>
    <name>A0A2G4EWE5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_019235</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tic20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000148">
        <property type="protein sequence ID" value="PHX53854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53854">
        <property type="protein sequence ID" value="PHX53854"/>
        <property type="gene ID" value="CP500_019235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005691">
        <property type="entry name" value="Tic20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510">
        <property type="entry name" value="PTHR33510"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16166">
        <property type="entry name" value="TIC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="157" mass="17746" checksum="03F2477E0F5642E0" modified="2018-01-31" version="1">MTWRGSTTVSDRIFACLPYLLPLVDGLAFGQFLFRQFPVLQLLFIPLAPLIQIYSLPFASLVIFFALYLGVVRNENISHFIRFNAMQAILLDIVLMLCGLVLPILRNAFQIAFIAETLYNMVFLGVLAAFFYAIVQSALGRYAEIPPISDAVYMQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWE7</accession>
    <name>A0A2G4EWE7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">BMC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Carboxysome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial microcompartments protein family. CsoS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53798">
        <property type="protein sequence ID" value="PHX53798"/>
        <property type="gene ID" value="CP500_019455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020808">
        <property type="entry name" value="Bact_microcomp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044872">
        <property type="entry name" value="CcmK/CsoS1_BMC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00936">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143414">
        <property type="entry name" value="SSF143414"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01139">
        <property type="entry name" value="BMC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51930">
        <property type="entry name" value="BMC_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="1" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC" evidence="5">
        <location>
            <begin position="24"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="BMC" evidence="5">
        <location>
            <begin position="129"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="257" mass="27665" checksum="F48FCC1DCB2CCD70" modified="2018-01-31" version="1">MNGQTNNPGGQSQSQRQEYFKDTALGLVSTKSFPAIVGTADMMLKSAGVILVGYEKIGSGHCTAIVRGRISDVRLAVEAGAQTAEQFGQFVSKLVIARPLANLEVVLPIGFRLTQLSESGSYSRLSNQAVGLLETRGFPAMVGACDAMLKSADVHLAAYEKIGAGLCTAIIRGAVADVAVAVEAGMYEAERIGELNAVMVIPRPLEDLEQTLPLASCWIEQRQPVMMPMSMKEKQQELIQLPDLQKLTISVEEEINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWH5</accession>
    <name>A0A2G4EWH5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-mannosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_019405</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000151">
        <property type="protein sequence ID" value="PHX53828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53828">
        <property type="protein sequence ID" value="PHX53828"/>
        <property type="gene ID" value="CP500_019405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004559">
        <property type="term" value="F:alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041147">
        <property type="entry name" value="GH38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011682">
        <property type="entry name" value="Glyco_hydro_38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015341">
        <property type="entry name" value="Glyco_hydro_38_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037094">
        <property type="entry name" value="Glyco_hydro_38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000602">
        <property type="entry name" value="Glyco_hydro_38_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09261">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17677">
        <property type="entry name" value="Glyco_hydro38C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07748">
        <property type="entry name" value="Glyco_hydro_38C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01074">
        <property type="entry name" value="Glyco_hydro_38N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00872">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="SSF88688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alpha-mann_mid" evidence="7">
        <location>
            <begin position="636"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1223" mass="137661" checksum="217A63C298D35AAB" modified="2018-01-31" version="1">MSASVPLASNNISEAIEKLRRLSRWDVQSGWKYCYSDSAVVHTVNICNWPLAELNEKSHIAWPSGKQVLYLGQQFVVPDNLSGYPVTGLRLLLNLTWWAEDAQLFVNGELVGVGDLFDCSVRLLLSPSAIPGDEFLVILRLVSPGHDCGALVRSVCVYEAADSAYFDPGFVADELEILQNSLSGNFQNLNSQYLPTENIVDRTFVVKGERLKSEIELAVGLIDWSVVCDRQKFDRSLSNLRQNLLRCLRDFQDVLTAEGAEGEKEKILLNISKNDDSISNAQCPMPNAQCPEVSNFSDQAYTSIYIGESSENSSIYKGKIYLLGHAHLDLAWLWPVAETWEAAQRTFESALKLQSEFPDLIFCHSTPALYAWIEEHRPDLFAAIKKQVAAGRWEVVGGMWVEPDLNLISAESMVRQVFYGQRYTQEKFGELMRVVWLPDTFGFGWQLPQILRDGGVDYFVTQKLRWNDTTEFPHGVFLWEGLDGTKIFSMMSAAIGENIESVKMANHLFDWQVKTGLQSAFWLPGVGDHGGGPTRDMLEVAKRWEMSPFFPNLQFAKAVDYLSLIESQFFPEISQTESQGDASIRESHPILGQDEVIGNLDEFESANFSEISEFESQGDASTLLPIPIWKDELYLEFHRGCYTTRADQKRNNRRCEELLYQAELLSSLATICAGAVYPKSELEIAWKQVLFNQFHDILPGSAIAKVYIDANLAFAEVDRTCRQILLQSLDAIASQISLPSPPQSDAQPILIFNTLNWSRSEVVALPIPDSNPENWQVYDSSGQRLVTQIQMCDRPKPQFTMLFWTSDIPAIGYRVFWLSHKNPETIESSSPKAPESEKTKLGQVTNHLTPKIALCQETHFDTPRKVLENELIRATIDGETGNLSSIWDKVNNREVLNIAGGNQLQSFQDSGQYWDAWNIDPNYQKHQLPAPILKDISWIAQGEIRHSLRVVQQIGKSEFCQDYIVEIGSPLLKIKTVVDWQEKHILVKAAFGLNVEADFVTCEIPGGAIERTTKPETAAEKAKWEVPILRWVDISNHDFGVSLLNDCKYGCDLQPNQIRLTLLRGSTWPDEQADIGIHEFTYAVYPHSGNWQDAGTVRQGYELNLPLLVQVLPKSEENQHKTLPTVGKLLDLSAENLVLMAFKQSEENPNSWILRCYESEGKEAVLELDSDLGLAISQQVNLLEQPISLPSQSDDGKSFKILSWKIASFAVNSSGLYSIIVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWP2</accession>
    <name>A0A2G4EWP2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_019080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000144">
        <property type="protein sequence ID" value="PHX53886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53886">
        <property type="protein sequence ID" value="PHX53886"/>
        <property type="gene ID" value="CP500_019080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="8">
        <location>
            <begin position="35"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="296" mass="31496" checksum="5F4EBD4023C1B1A1" modified="2018-01-31" version="1">MSGTVTSPKNLNQQRPLATPSADTSSSLLGDFIQETLALTKRLFIQLQRRPSTLVAGIIQPLMWLVLFGALFENAPAGLFGESQNYGQFLGAGVIVFTAFAGALNAGLPIMFDREFGFLNRLLVAPLASRFSIVLASAIFIVTLSFIQTGTIVSAGAFLGAGFPGIAGLGAIALIVLLLVLGVTGLSLGLAFALPGHVELIAVIFVTNLPLLFASTALAPLSFMPHWLQVVVTLNPLSYAIEPIRYLYLHSDWSLASEVMQAPWGTVTFGGALLVLLAFDLVALLSIQPLLRRRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWZ5</accession>
    <name>A0A2G4EWZ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000129">
        <property type="protein sequence ID" value="PHX54049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54049">
        <property type="protein sequence ID" value="PHX54049"/>
        <property type="gene ID" value="CP500_018195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="1">
        <location>
            <begin position="6"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="210" mass="24066" checksum="7662C78C267D530B" modified="2018-01-31" version="1">MEFPNFQVCDRDLPDSLLSYYLTAEAIAVDTETMGLMPWRDRLCLVQLCNPEGKVTVVRIAKGQTAAPNLKKLMEAENIEKVFHFARFDMATMRYNLSIDIAPVFCTKLASKLARTYTNRHGLKELILELEKVELNKTSQSSDWGNATNLSDDQLNYAANDVRYLLSAKQKLTAMLQREELWEIAQQCFQCLPVFVSLDLLQYKDVFEHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX28</accession>
    <name>A0A2G4EX28_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_017960</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54083">
        <property type="protein sequence ID" value="PHX54083"/>
        <property type="gene ID" value="CP500_017960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="66"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="136"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="218"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="291"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="344"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="418"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="671"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="799"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="924"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="997"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="1073"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="1329"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="465"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="1378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1450" mass="160581" checksum="57605A320B4AEF7F" modified="2018-01-31" version="1">MSLLQAPCFPMKPYSISRFTTGTALLLTILLLFAFKSTSGILFLAIAMVTAWYAGLKSTEKELQTERDIISNVIDMAACLIVVLDREGRIVRFNQVCEKTTGYSFAEVENKFVWDLFLISEELNPVKTIFAKLNAEDGVSQYINYWLTKNGEMRLINWSNTVIVDSHGLVEYVIATGIDITDCQQAEIALALSYADLETRVKQRTAELTVAKEALQAQEERFRSLSSCSPMGIFMVDIQGCYTYTNPRCQAIYDMSFEELLDGGWQNRIHPEDREIVLTQWLDYTREGGEYAMEYRWQISDGIVHWVNVSCSPMFSDCGELMGHVGTVRDVTERQQAQAALSSSEQQLRTLLENTPDIIIRTDRELRYVYVNQAVERSQGQAVSFFIGKTSQEIGMPPELCQLWDETLYKVLETGQEEIIEFQVPSSSGLRTYQSRIVPEFDSEGAIQYALIVARDITELKLAEVQKAQLTIEQAAREKAEIEQQRSRFLAEVSKMLAASFDGETVLQNVAQLAVETAAEGCCIHLTEIDGKVRLVAVAHAEASMLDAMNKLTLRNPIDNNSVNGYPLVIRTGKSELITEVSQEKLAAGAENEAELEVWRSLNIGSHACVPMTARGRVIGAITCFTSQSGRHYNSEDLAMLEDLAYHVGLALDNARLYAEAQQALAQTSESFALIDSLLEASPLGICFLDREMRYIRINQVLAELNGLTTEQHLGQDFRQLLPESAAQFAPVIQQVLETGQPILNVDISGESKGKPEYFGHWVGNYYPVKNQNGETIGAGIILTDITIAKQTEIALRESEIRFRSVVESNMSGIGFWDIEGAISGANDALLEMIGYTREELVSGKLRWLELTPPEYQYLDRIALEQIAAFGSCTPFEKEYIRKDGSRFPVLVGGGHFQGCKDKGSFFILDISDRKQAEAARSEINKTLETLIQACPLAITVFSAESGVVKLWNPAAEKIFGWKESEVIGQFLPSVSPDNQEEFKAKLKEIRNGNAIAGMETVRHKKDGSQIEIGLWATPVRDGNGNINCMSIVADISDRKQAETERTQLLDRERAARAEAEAINRLKDEFLATLSHELRTPLNAILGWAQVLRNRPYTPATLAIALESIERQGRVQTQLVEDLLDVSRIIQGKLSLKTGWLDIVKTIEVAMNSVCFTAEAKAIIVNLELDPTLGLIWGDIHRLEQIVSNLLTNAVKFTPPGGTVELRLSRDVGCSIANSPLPITNYLQIQVSDTGKGISAEFLPHVFDRFRQADGSITRADNGLGLGLAIVRHLVELHGGTVTAESPGKDRGATFTVKLPLKQPKSQKSRLTRVGNSEPFPPGILAGLKVLVVDDEPDNRQLLTVMLAEWGASAIAASSVAEAIEILGHSQPDILVSDIGMPIEDGYSLIRKIRSSESGLTKHLPAVALTAYAREEDRKQAISAGYDERLTKPIEPSQFVAVLAKLAGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX36</accession>
    <name>A0A2G4EX36_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoside triphosphate pyrophosphatase</fullName>
            <ecNumber evidence="2">3.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nucleotide pyrophosphatase</fullName>
            <shortName evidence="2">Nucleotide PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + H2O = a 2'-deoxyribonucleoside 5'-phosphate + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:44644"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-phosphate + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23996"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Maf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000130">
        <property type="protein sequence ID" value="PHX54036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54036">
        <property type="protein sequence ID" value="PHX54036"/>
        <property type="gene ID" value="CP500_018235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036218">
        <property type="term" value="F:dTTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="216" mass="23653" checksum="D72CE1970C21D3D4" modified="2018-01-31" version="1">MKTPTFILASASPARHKLLQNAGIKVIICPSDFDEGQIQMRDATKLVQVLAKGKADAVAESLRANSHPQIPNPKSCLVLGCDSILVIDGEIHGKPKDAEEAISRWQKMRGKVGELYTGHALIDTRFDDLDETMDRSIVRCQVTKVHFAEVTSHQIAAYVATGEPLACAGCFALEGKGGFFIEKIEGCHTNVIGLSLPLLRQMLRDMGYDVSDFWQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX44</accession>
    <name>A0A2G4EX44_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53717">
        <property type="protein sequence ID" value="PHX53717"/>
        <property type="gene ID" value="CP500_019980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="9869" checksum="8B94B0B019F603E3" modified="2018-01-31" version="1">MTEKEDFLHPRHRYYGDFTPENLAFNANLQEFAQKITYICSLETGGKISAEKAYKDIKALWKDLKSSKKNLGIGQKNLSNDEENSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXB4</accession>
    <name>A0A2G4EXB4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_019630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000155">
        <property type="protein sequence ID" value="PHX53787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53787">
        <property type="protein sequence ID" value="PHX53787"/>
        <property type="gene ID" value="CP500_019630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="164"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="291"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="396" mass="45207" checksum="F0AFD753E3079103" modified="2018-01-31" version="1">MIVLEFKLKGKAEQYRVIDEMIRTAQFVRNKTLRYWMDNQGVKLVDLYKQCAVMAKEFEWAGKLNSMARQASAERAIFAIQRFFANCKAKKPEKGYPQFKKHSRSIEYKTSGWALSTDKRCLTLKDGFAAGKFKLIGSRDLHFYAPEEIKRIRIVRRADGYYAQFCINVERKEELVLTGKAIGIDVGLNHFYTDSNGETVANPRYLRKSEKALKRLQKRVSRKKKGSGNRKKAINKLGRKHLKVARQRKDFAIKTALCAVKSNDFVAYEDLQVRNMVRNHKLAKSISDAAWSQFAQWLEYFGKVYGKTVSAVAPQYTSQECSNCGNLVKKTLSTRTHICECGVILDRDHNAAKNILFKGLKQAKINLNTAGHAEINAWGQNNLYSMVATSTSKLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXF3</accession>
    <name>A0A2G4EXF3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54213">
        <property type="protein sequence ID" value="PHX54213"/>
        <property type="gene ID" value="CP500_017245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="22"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="13246" checksum="6E1C026C809C030F" modified="2018-01-31" version="1">MPRIQLDLAFNRLGRLAEQTIAFCKKWRIVELALFGSVLREDFCPETSDIDILVTFAPDYRWTFDDAMQMQEELETLCGRKVDILSKQCIEQSINWIRKQEILNSAKVIYVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXF4</accession>
    <name>A0A2G4EXF4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_017260</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54215">
        <property type="protein sequence ID" value="PHX54215"/>
        <property type="gene ID" value="CP500_017260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="37"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="357"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="399"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="441"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="483"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="525"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="567"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="602" mass="65712" checksum="32864673DB36B304" modified="2018-01-31" version="1">MSLCINPTCPKPDHSQNTNNRHCQSCGSDLLLQGRYRVMRLLSDKSGFGKIYTAEEPGISKILKVLKEYFNNEPKVVELFQQEAKVLAQFQHLGIPKVDGYFQYQTRNGLILHCFVMEKIEGPNLEEWLQQQGNHPISERQAIAWLKQLAEILHLVHGKQYFHRDIKPPNIMLRPNGQLVLIDFGTAREATYTYLAKVGVGHRITAVVSAGYTPPEQQNFQAVPQSDFFALGRTFVHLLTGQYPLNFYDAHNDVFRWRQAANISPSLADFIDNLMARRPGDRPHNTQVLLQRIEELAQKLAKRKTNLPVGVAAGVLLVLGGGIGFWFSKLGGSSVSSPSPVVRSRSSLENVSLVKTLTGHSESVSSVAISPDGQTLVSGSDDKTIKIWNLTTGNLIRTLSGHSNYVYSVAISPDGQTLVSGSLDNTIKIWNLATGNLIRTLSGHSNSVSSVAISPDGQTLVSGSYDNTIKIWNLATGNLIRTLSGHSNSVSSVAISPDGQTLVSGSYDNTIKIWNLATGNLIRTLSGHSNSVSSVAISPDGQTLVSGSYDNTIKIWNLATGNLIRTLSSHSNSVYSVAISPDGQTLVSGSGDDTIKIWRVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXL9</accession>
    <name>A0A2G4EXL9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycine cleavage system P-protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">gcvP</name>
        <name evidence="9" type="ORF">CP500_016930</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the GcvP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000110">
        <property type="protein sequence ID" value="PHX54292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54292">
        <property type="protein sequence ID" value="PHX54292"/>
        <property type="gene ID" value="CP500_016930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00711">
        <property type="entry name" value="GcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="995" mass="108902" checksum="65FB9665D814EA86" modified="2018-01-31" version="1">MVLYSSEIESNQQQNLTPIDGFARRHIGPTPREIQEMLDILGIDKFDDLIDKTVPAAIRLPHPLELLAAKSEYAALAELQEIASKNQVFRSYIGTGYHDCITPPVIGRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMIIDLTGLEIANASLLDEGTAAAEAMAVSYGVSKNKGKAFFVAQDCHPQTIEVVQTRAKPLGIDVIVGDHRDFKCDRTIFGALLQYPATDGAIYYYTDFIASAHEVGALVTVAADILSLCVLTPPGEFGADIAVGSTQRFGIPMGFGGPHAAYFATREEFKRQVPGRIVGVSKDANGKSALRLALQTREQHIRREKATSNICTAQVLLAVMAGMYAVYHGPQGLKEIAEKVRDLTALLASGLKSLGYKIGAEPFFDTLRVELGDKQLSEILEAAQNYQINLRVFDEKTVGISLDETVTAGDVKKLLAIFADEKDAINADGDIFVSMSLDADDFTSSLVYPAFCDRTTSYLTHPVFNSYHSETELLRYMHRLEAKDLSLNTSMIPLGSCTMKLNATAEMLPVSWPEFSKIHPFAPSHQTRGYQMMFVQLEQWLAEITGFAGISLQPNAGSQGEYAGLLVIRQYHEHRGESHRNICLIPQSAHGTNPASAVMAGMKVVAVDCDSQGNIDVADLQKKAEKYKNELAALMVTYPSTHGVFEAEIKEICEIVHQAGGQVYMDGANMNAQVGLCRPGDFGADVCHLNLHKTFCIPHGGGGPGMGPIGVMSHLVEFLPSTSIFNSEQSAANSQQRTVNSEQSTVNSQQTSVGAVSAAPWGSASILTISWMYIRMMGGVGLTEATKVAILNANYMAKRLESYYPVLYKGKSGLVAHECILDLRLLKKTAGIEVEDIAKRLMDYGYHAPTVSWPVAGTVMVEPTESESKQELDRFCDAMIAIRAEIAEIENGNVDAQNNVLKNAPHTAESLMVDEWNHPYTRAQAAYPTAWTREHKFWPAVGRIDNAFGDRNFVCSCLPMEAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXX4</accession>
    <name>A0A2G4EXX4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 17">Photosystem I iron-sulfur center</fullName>
            <ecNumber evidence="3 17">1.97.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15 17">9 kDa polypeptide</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16 17">PSI-C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13 17">Photosystem I subunit VII</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14 17">PsaC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">psaC</name>
        <name evidence="19" type="ORF">CP500_016605</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 17">Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>hnu + oxidized [2Fe-2S]-[ferredoxin] + reduced [plastocyanin] = oxidized [plastocyanin] + reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:30407"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10039"/>
            <dbReference type="Rhea" id="RHEA-COMP:10040"/>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <dbReference type="ChEBI" id="CHEBI:30212"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
            <dbReference type="EC" id="1.97.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="17">Binds 2 [4Fe-4S] clusters. Cluster 2 is most probably the spectroscopically characterized electron acceptor FA and cluster 1 is most probably FB.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">The cyanobacterial PSI reaction center is composed of one copy each of PsaA,B,C,D,E,F,I,J,K,L,M and X, and forms trimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Cellular thylakoid membrane</location>
            <topology evidence="17">Peripheral membrane protein</topology>
            <orientation evidence="17">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.97.1.12" evidence="3 17"/>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015175986.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000107.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54336">
        <property type="protein sequence ID" value="PHX54336"/>
        <property type="gene ID" value="CP500_016605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009773">
        <property type="term" value="P:photosynthetic electron transport in photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01303">
        <property type="entry name" value="PSI_PsaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017491">
        <property type="entry name" value="PSI_PsaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03048">
        <property type="entry name" value="PS_I_psaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 17" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 17" id="KW-0408">Iron</keyword>
    <keyword evidence="12 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 17" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8 17" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0677">Repeat</keyword>
    <keyword evidence="17" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 17" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="18">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="18">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PHX54336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="8816" checksum="57B7CCBB30E5CC85" modified="2018-01-31" version="1">MSHSVKIYDTCIGCTQCVRACPTDVLEMVPWDGCKAAQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGAETTRSMGLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXY8</accession>
    <name>A0A2G4EXY8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000104">
        <property type="protein sequence ID" value="PHX54389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54389">
        <property type="protein sequence ID" value="PHX54389"/>
        <property type="gene ID" value="CP500_016395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="16418" checksum="9335C49DE7952A47" modified="2018-01-31" version="1">MEADFVCVEASLYALDSVGWVERQRNPTLDFRRVGFRSRSTQPTVFTAEADFVCVEASLYALDSVGWVERQRNPTLDFRRVGFRSRSTQPTVFTAEADFVCVEASLYALDSVGWVERQRNPTLDFRRVGFRSRSTQPTVFTAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY33</accession>
    <name>A0A2G4EY33_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-beta hydroxysteroid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54396">
        <property type="protein sequence ID" value="PHX54396"/>
        <property type="gene ID" value="CP500_016255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="311" mass="35045" checksum="7E911C1454C7672A" modified="2018-01-31" version="1">MRILMMGGTRFIGVYLTRILAAQGHEVVLFNRGNKPVPVSGVQQIQGDRTNLDQLKDKLSTEEFDVVFDNNGRELSDTKPLAEIFKGRVQHFVYMSSAGVYLKSDQMPHIEGDATDPKSRHLGKCETETYLAESGLPWTSIRPTYIYGPQNYNDLEAWFFDRIVRDRPIPIPGNGMHFTQLGHCQDLARAMAAVLGNQRAIGQIYNVSGDRFVTFDGLARACIQAAGKSVDSIKIIHYDPKQFDFGKKKAFPMRLQHFFASVNKAVTELNWQPEFDLVSGLKDSFQNDYVVSGRDKAEIDFSVDEQILKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY76</accession>
    <name>A0A2G4EY76_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000097">
        <property type="protein sequence ID" value="PHX54482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54482">
        <property type="protein sequence ID" value="PHX54482"/>
        <property type="gene ID" value="CP500_015825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="165" mass="18244" checksum="23FE3467B5F3A764" modified="2018-01-31" version="1">MDRLQTDIEAICSQIEALRRERQQISVAAATPIGDSPQAIADAYRRHARETAQVSVEVKGIDDAIAALSAQLSQKQQQSGNLQKMSSMEQQVEDGRTLARGHAERINLLAAELASEVKGLKAIADQISPSYWQVYYKPFITGFKSISVPYVRSDGDVWTIVNRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY98</accession>
    <name>A0A2G4EY98_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromophore lyase CpcT/CpeT</fullName>
            <ecNumber evidence="3">4.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cpcT</name>
        <name evidence="4" type="ORF">CP500_016230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CpcT/CpeT biliprotein lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.-.-.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54430">
        <property type="protein sequence ID" value="PHX54430"/>
        <property type="gene ID" value="CP500_016230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017009">
        <property type="term" value="P:protein-phycocyanobilin linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16338">
        <property type="entry name" value="CpcT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01460">
        <property type="entry name" value="Chrphore_lyase_CpxT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010404">
        <property type="entry name" value="CpcT/CpeT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038672">
        <property type="entry name" value="CpcT/CpeT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35137">
        <property type="entry name" value="PTHR35137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06206">
        <property type="entry name" value="CpeT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="197" mass="22517" checksum="7655542406689BF9" modified="2018-01-31" version="1">MSHSTDIITLARWMASDFSNQAQAFENPPFFAHIRVCMRPLPVELLDGVSLYLEQAYDIELNSPYRVRVLKLVPMADRIDIENYAIANEEQFYGASRDRQKLQELKTAEFKLMPGCTFITHWTGSSFKGRVEPGKGCMVVRKGKKTYLDSEFEIDGDKFVSHDRGRDPETDAHVWGALAGPFEFTRRASFADEIQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYF6</accession>
    <name>A0A2G4EYF6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CP500_015355</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54563">
        <property type="protein sequence ID" value="PHX54563"/>
        <property type="gene ID" value="CP500_015355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="17">
        <location>
            <begin position="373"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="14">
        <location>
            <begin position="447"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="15">
        <location>
            <begin position="722"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="16">
        <location>
            <begin position="879"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="417"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="11">
        <location>
            <position position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PHX54563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1132" mass="125393" checksum="BD65AEE2D8EF88B3" modified="2018-01-31" version="1">MSTLSLNRLATKLSGKVNLRTVVIVPFVLQVFAAVGLVGYLSFKNGQRSVNDLAGQLMGEVSNRIEQNLETYLETPHQINQSKLDSVKLGFVNMKDLSAWEKYLWRQVQLYPYINFTSIGNKNGEYRTGEKMSNGTLLINASGPSTGFDFHSYNTNDTGDRTTVAAVVKNFDIRQHPSYALAALEVKPTWSSVYVSFLEPTLILSALQPVYDSQKQLEGVLVTALRLDAIGQFLNSLKIGKSGQTFIVDKNGILLATSTSEKPFRTQKNQKELFKVTESSDAVTQATAKYLVTQFQDLHRIQKFQQINFEINGKQQYLKVLPFQDGKGLDWLIVVVVPEADFMAQIDANTQTTILLCLAALGMATVVGIFTSRWIIQPILELKDAAIALSEGQFDKTVKLERSDELGVLAKAFNSMAAQLQASFTALEAKNSELQRLDKLKDEFLANTSHELRTPLHGIIGIAESLIDGATGQLPEKTNMNLALISSSGKRLSSLINDILDFSQLKHKTLELHVKPVGIREIVYIILTLSQPSIGKKNLQLLNSISPELPPVAADENRLEQILYNLIGNAIKFTESGTVEISAELLMGNEQSSMPSSQLAITVSDTGIGIPAEKLERIFESFEQADGSTGREFGGTGLGLAVAKQLVELHGGQIKVSSTVGVGSQFTFTLPVSESQPQVDGKYPLVAEGDRNFSRHQVTADLPIIYSQSPACQEVLEGDKIQVLIVDDEPINIQVLINSLSSENYAITQASNGLEALSLIEEGFKPDLILLDVMMPKMTGYEVCREVRKKYSPLELPILMLTAKNQTSDLVEAFNLEANDYVTKPFIKKELLSRINTQIRLAKLNAAYGRFVPHDFLNLLGKPSIIEVKLGDNQAKNMTVLFADIRSFTALSEQMTPPENFAFINTYLGRVSPAIRKNNGFIDKYIGDAVMALFPTSPDDGVRAAIDMQKEVNVYNKQRQENDLAPIAIGIGLHVGNLMLGTIGERERMESTVISDAVNLASRLEGLTKVYGSGILVSDTIISGLSDREKYKYRFVDRVTVKGKTTALSVFEIYDTETEQSIALKQQTAEIFQEALDFYYKEKFVLAQKIFQHILHINPEDKVAMLYFKRSRKYRMYGVPDGWAGVEALTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYP7</accession>
    <name>A0A2G4EYP7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54610">
        <property type="protein sequence ID" value="PHX54610"/>
        <property type="gene ID" value="CP500_015135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013861760" evidence="2">
        <location>
            <begin position="31"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="250" mass="28447" checksum="3F3565C80EA94CCF" modified="2018-01-31" version="1">MKTHNFLNSIAAIVLVAGLALTGISSGAVAEQIGNGDRIDGVIRRTSTIYRFRNMWVPGTPIEELRGQEYTFTANEGDDIQVYLDTNRRGGFTPVMVLFYGNNKQVAFTQETSFNYQIPRRGDYRLLVLAKDAARGGNYSLEVSGIQGDRRARNSRDNRGDNNRYDGERILRNDFGLRAVDCNQRRSMVRVRFDDEDTTYCAIPTRDYPQGDYYYNPRTRDLDSARLDDSRYDAGRDQCRVMVGGKCVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYV3</accession>
    <name>A0A2G4EYV3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_016565</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54367">
        <property type="protein sequence ID" value="PHX54367"/>
        <property type="gene ID" value="CP500_016565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019494">
        <property type="entry name" value="FIST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013702">
        <property type="entry name" value="FIST_domain_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016741">
        <property type="entry name" value="UCP018953"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08495">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10442">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018953">
        <property type="entry name" value="UCP018953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00897">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01204">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FIST" evidence="7">
        <location>
            <begin position="37"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="FIST_C" evidence="8">
        <location>
            <begin position="249"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="416" mass="45071" checksum="9BC30E28068BE0FB" modified="2018-01-31" version="1">MYTQNEMQWVSALSTRPSLESALKEVIEQADRLLEGPADLGLIFISSAFASEYSRLMPLLKELLPIPALIGCGAGGVIGANRGGLTEEVEGSPAISLSLARLPGVNVRTFHVEAEQMPDLDSPPDTWVDLLGVPAQEEPQFIILADPFSSKINDFLQGLDYAYPGAPKVGGLAGGDGTRTTALFCNYELYREGTVGVALSGNIVLETIVAQGCRPIGRPYRVTEGERNILLKIEEQTDDPGFGGTGRSPLEALRELVQTLSEEDQELAQHSLFVGVVSDEFKLVLEPGDFLVRNLLGVDPRVGAIAIGDRVRLGQRIQFHLRDARTSAEDLEMLLERYQRAIEDRGTSSAGALMFSCLGRGEGLYGEPNFDSRLFGQYLNNIPLSGFFCNGEIGPVGGNTFLHGYTSVFAICRQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYZ9</accession>
    <name>A0A2G4EYZ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000082">
        <property type="protein sequence ID" value="PHX54716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54716">
        <property type="protein sequence ID" value="PHX54716"/>
        <property type="gene ID" value="CP500_014635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="294" mass="30129" checksum="B5BE8A067C9B1C99" modified="2018-01-31" version="1" fragment="single">PTPTPTPSVTPTPTPTPTPTPSVTPTPTPIPLVIPIPTPTPTPTPTPSVTPTPTPTPIAINTPPVGTIGTIDRGEPTNFPQNQVVDNQYLLSDNDDTSIPQSAFGQPIFGLSGNDKLTGSADNDTISGNEGADTIDGGDGNDNLFGGKKSDQLSGGNGNDFLSANNENDTLTGGDGNDILRGGKENDVLIGGNGDDELWGDKGFDVLTGGAGKDTFVLQYTATNPSQADVITDFTSDDKIKLIGATFSQLTFESVNVILDGANAVASTAIKSGNDYLGVVYNVNPTALNSGSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ45</accession>
    <name>A0A2G4EZ45_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_014400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54770">
        <property type="protein sequence ID" value="PHX54770"/>
        <property type="gene ID" value="CP500_014400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="69"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="215"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="567"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="642"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="712"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="973"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="1100"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="1022"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="1149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1235" mass="137135" checksum="E561EE275EBB8FEB" modified="2018-01-31" version="1">MHPYLQRQLEQLNLTDHSPPLTADRWRLFLEEVSRSYDSNGQSAVVKEASENSQDEVLQSFPDDSTISEFDRLRATVNSLGAGLFILDTQGLVLCVNPEAERLLGWRESELVGVALLSRIGSKQSKAKKSKVLSSNQPEASNTENLPIATSLSLQQAIASNLPYSNSDDQFLCRDGKILPVSYFFNPAPLGPNISVLVFFDIGEQKRSAREQERSLSMLQSVLESTDAGIIAVDNNGNVCNYNQKFVEMWGLSEAQEFNRSTVGTLQKPAKTAFPFALRQLKDPQEFLKNVMKVSAHPDTQIDDLLEFKDGKILELNSRPSKVGSKIVGRVWSFRDITDRQRVEQALQHRVEFDQLITSLSTHFINQSVSEIDQGINHALEAIATKSHFDRSYIYLLSEDKTQFKNIYEWCSEGRQTLRDQIPQISLQHIPWIAQKIAQFESIHIPEVSELAPPQLVEIAYFGDREQPTESLPNPPSQITNKNLITAFASIGESLNNLEAKKLDKHIQSLSIIPLVCSQKVIGFIGFDTQKQTAKRSPEISTQLKIVGEMLANALERQRVESALRQAEIKYRGIFENAVEGIFQITPDGSYLSANTALARIYGYDSCAQMLAKLTDVKNPSYSNPHRRAELIVAMTNVGEISKFESQIYRLDGSPIWIAENARSICDESGNVLYYEGTVEDITDRKRAESAMQFALEAAESANRAKSTFLANMSHELRTPLNAIIGYSEMLQEEAEDSGNENSVPDLEKIRSAGKHLLALINDILDISKIEAGRMELYLETFDIPSLIDSAVATALPLIEKNGNILEIYCPNNLDTMHADMTKVRQVLLNLLSNAAKFTKNGKIAIGVENINNEQLKIKNQEESSQISISNAEFLSFRVSDTGIGMNPEQLQRVFLPFTQADASTTRKYGGTGLGLAISQRFCQMMGGTIEADSKLGVGSAFTVILPSQIKLPETENKIHDSKRPLLVNAVGTVLVVDDDPISRDLIERALTRQGLHIELASSGEQALELAKKLRPDAITLDVMMPGMDGWAVLSALKADPDLAEIPVILLSFVGNKSLGFALGASDYLTKPVDGKRLAALLRKYRRDQDNLANNDLTCQILIVEDDVTTRGILRRILEKQGWAVTEADSGRAALDRLDVSRPNLILLDLMLPEMDGFELIGEVRKSYSVDPIPIVVITGKDLTPAESHQLNGCVDRVLKKGVYSCDSLLRDVRSIVNDRFDRRYGSKGKEGTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ65</accession>
    <name>A0A2G4EZ65_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_014210</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54815">
        <property type="protein sequence ID" value="PHX54815"/>
        <property type="gene ID" value="CP500_014210"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="11">
        <location>
            <begin position="23"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="10">
        <location>
            <begin position="115"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX54815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="31123" checksum="066B2585E599DB96" modified="2018-01-31" version="1">MKAILPPWIVLDSLLHNWLLEDIGRGDRTTSALFPANSIQGTAKWIVKEAGVIAGLPIAHRTFKLLDSNLSFIPQVPEGKLCEKGEVIAEISGNFDALLTGERVALNLAMRLSGIATLTQKYVDKIADLPVQLVDTRKTTPGLRLLEKYATQIGGACNHRMGLDDAVMIKDNHIAAAGGIAEAIALIRNSIPYPLTIEVETETLAEVETALQHNADIIMLDNMSFDLMRQAVAIIREKGDRVKIEASGNVTLETIRSVAETGVDYISTSAPITRSTWLDLSMKINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZD8</accession>
    <name>A0A2G4EZD8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54869">
        <property type="protein sequence ID" value="PHX54869"/>
        <property type="gene ID" value="CP500_013845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018335">
        <property type="entry name" value="Tscrpt_reg_HTH_Crp-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00042">
        <property type="entry name" value="HTH_CRP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH crp-type" evidence="1">
        <location>
            <begin position="114"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="22456" checksum="9B5B0E0875736666" modified="2018-01-31" version="1">MTISSLSAQTFEETKRHIFSRRAYLPNRNNALWQIETGVVRTVTWLEDGTIITLGLWGSGDAIGKPISKCDPYQMECLSKVEAILLSADRWLNRDILLNHIQQAEEFMVMRGYKKVDFMLYKLLNWLAKKFGSEIEKGHLIDMNLTHQDIAEILGTSRVTVTRTLGIFEQQGLIERLPLHRIILQPSEVWHYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZF2</accession>
    <name>A0A2G4EZF2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_013700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54885">
        <property type="protein sequence ID" value="PHX54885"/>
        <property type="gene ID" value="CP500_013700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045434">
        <property type="entry name" value="EAD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19959">
        <property type="entry name" value="EAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="249"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1388" mass="156213" checksum="DFE40F0A6303F386" modified="2018-01-31" version="1">MPSKKKVTYGPTVKERAKRLLEALLDYVNWELEDVGGISLNHKWKDETTDKPKLVIKTELRTLEFLTAKDKHEGKLTTTEIRQALNQHLKDFLEILEDHRLETQGDDEWHFTLTLWSKKDKQKNLEQFEIKWESLRPEKSKKQEETLRETVAGKTPKPKEETINWQEICRHNLAQQKQLTTNPFTNANGMTPQLDGVYVPLAIVERQKPKPQPRNQQEEKEKETEKLIPIAEERFFEDVLRQGKSDISQGRKIAIIGEPGAGKTTRLQKIADWILEQDLGLPIWIDLAELGDRDICQYLEKVWLSRCQGEVTRRDLEGQINRVWLLLDGVDEMAHTQGMQQLAKDLLRSWVQAARVVVTCRVNVWEADKNAFSGFDVFRNLEFNPEQVTEYIRRWFAGMGDAATGETLEFALAESENSRLKELIQNPLRLWMLCQIWSSRQGTLPDTQAKLYGSFIKYIYRWKEQFIKSYAKLCDKTQSECQKLLHEGLGELAKVAIDGKSSRFRLSYQLVSQYLGARSDETSLLSLALSLGWLNRVGIDFDEPEESVYAFYHATFQEYFAALAVDDWDYFLPRNHVDFPVVGKEYRIFEASWKQVILLWLGLEDVNRKQKEEFIEALLDFKGGCNDFYEYQAYFLAAAGIAEFKDCSQADAIVAKIIDWGFGYFSIEKQKWQTFLDPIAKGAIGTLLQTNYSIDVNQLIDLLTTTEDENIPKVVYILGKIATSNPEAIAALIQLLSATNDCGLTRWRVAESLGKIAIGNSEAIASLIGIISTTTDTYIRYEVSKILDKIAVDNSEAIAALIEILSATTNVSIRSIVANILGKIAIGNSEAIATLSAILLGTNDEKKLFCIAYILGKIDKGNPDVVAALINNLSKTNDEYTRRMFAHIFSLIGTENPEVIAALIGILSATNDENTRRIVAYSLAINGTGNPRAIAALIELLSANYASCHDHVIMVWREITTEKSEVIAALIEILSATNDKDTRWTVADSLVKIDPGNPKVIAALIKLLSTTNDENIYQIVADSLGKIDPGNPKAIAALIGILSATNDEDTRWRVAESLGKIDPGNPEAIAALIKLLSTTNDENIHQRVADSLGKIDPGNPKAIAALIKLLSKTNDEYTCRIVAESLGKIDPGNPEAIATLIEILSATNDDHTRGNVTQSLNKIVQNDQMPSVVSALQQFHCDQTHETNSDLYKNCFEIIWNCAQNIPYATFYQAWHHQLTTPHPEVPETTGVGSTPFTQSLNLADLPNILDARLVETQLIESLQLICIDTSKFIDSHNPALEIYGQFLDQNCPQRPNGEPETLPQLKSYWNQLHRHSDKHPILIFYEDPTSPAAQGLSPTFLEALTRFDGTLCLITDTPHPPLQTFSPHDPDLLQTVVNWLKRVHLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZI3</accession>
    <name>A0A2G4EZI3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDSL family lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54913">
        <property type="protein sequence ID" value="PHX54913"/>
        <property type="gene ID" value="CP500_013575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="140"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="300" mass="33681" checksum="E044D59AD2F2CD4F" modified="2018-01-31" version="1">MEKFGGFSGRRAYRPIFAKERSRNVPFWALLSLLTNGVLIVTVVQLMTGGQELPESSPASAAVSAARLDEIIPQGNSAKSVSDQPISGQRHKWTYQQWVTQLGREAEAVAMNRPSKLTVLVGDSLSMWFPTKLLPIDRIWLNQGISGETSVGLLKRLQLLDRTQPDAVFVMIGINDLLKGASDEGILDNQRQIIRDLRWAHPKAQVVVQSILPHSGEQATWENRDRLLAISNSRIREINRRLREIASVENALYLDLYPMFTDADGNLQTELSTDGLHLNDRGYLVWRSALQLFGQIQLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZJ4</accession>
    <name>A0A2G4EZJ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54936">
        <property type="protein sequence ID" value="PHX54936"/>
        <property type="gene ID" value="CP500_013340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7453" checksum="ACF530BA5CC2EABC" modified="2018-01-31" version="1">MGESETGFLRKSLIFTRRCGKKPGFLGVVSQSETGFLREYSSLALNLGKNPVSWVGANMETAPCPLVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZS8</accession>
    <name>A0A2G4EZS8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2839 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55014">
        <property type="protein sequence ID" value="PHX55014"/>
        <property type="gene ID" value="CP500_012930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021262">
        <property type="entry name" value="DUF2839"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10999">
        <property type="entry name" value="DUF2839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8080" checksum="02A0AB8CE723C260" modified="2018-01-31" version="1">MGESKRRKEAIGDKFGQEERIYPWLPITKTQSADFVKWTSRGSWIGISLLVGWWIVVRFVGPAAGWWVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F000</accession>
    <name>A0A2G4F000_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="5" type="ORF">CP500_012750</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55086">
        <property type="protein sequence ID" value="PHX55086"/>
        <property type="gene ID" value="CP500_012750"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="127"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="20555" checksum="08FFE992F83AAD7E" modified="2018-01-31" version="1">MNAEDLKVLRDRLLDLLCEFAYREGDFVLSSGQKSSYYINCKPVTLHPEGALATGKLLLSMLAADVDAVAGLTLGADPIVTAVSVVSALGDRPIPALIVRKEAKGHGTMAYIEGPTLSEGANVVVLEDVVTTGKSAMQAVERLRGAGYQVDRILSLIDREQGGAQFYHSVGLDFEAVFTIKDLQKWMANRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F027</accession>
    <name>A0A2G4F027_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55111">
        <property type="protein sequence ID" value="PHX55111"/>
        <property type="gene ID" value="CP500_012615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="300" mass="31372" checksum="63B99644EEAA02A5" modified="2018-01-31" version="1">MEVTELLKEYENGNRDFAGVNLSGANLSGAILVGINLSKANLSSANLSRAYLTKAQLNGANLHRANLSFAKMSEVRLADAEMTKTNLSGAFLVKAKLPRAKLSGAGLIGSNLHSAILWSANLCNADLQFINLRGANLTGANLNWANLSGAKLSGAMLFGAQLTGICLRKAYLNGIDLSGTDLNGVNLSEAKLNGVNLEGSNLVAANLSGAQLRNVKLTGANLTRANLTGVSLVQANLDWARLCYADLSEADLREATLMGANLEGTLLARATLSESVSRYFCLTVAGAVAAWQTETITATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F065</accession>
    <name>A0A2G4F065_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Urease accessory protein UreD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ureD</name>
        <name evidence="4" type="ORF">CP500_012195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UreD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55138">
        <property type="protein sequence ID" value="PHX55138"/>
        <property type="gene ID" value="CP500_012195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01384">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002669">
        <property type="entry name" value="UreD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33643">
        <property type="entry name" value="PTHR33643"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01774">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="291" mass="32600" checksum="739B4784C5D249C7" modified="2018-01-31" version="1">MIQNSTEQPTNNVQNGWHGSLNLVYANRDGSTQIIQNQMQAPLKVQRPFYPEGKEVCHSVILHTAGGVVGGDRLSSHFHLQPNAKALITSAAAGKIYRSNGLESQQNIDIQLEPGANLEWLPQETIVFDGAIYRQNLRVELAPKARILLWEITRFGRSARGEKFLSGKWRSHTEIWQQNSPLWIDRQLLKGGETMLESPHGLAGKPVVATLAWVGEPVTTELVEKVRNLPSEATIYPGNCTIGVTRIPNGLLCRYRGTSTTAARDWFVSIWDLLRLSFSERPCCLPRVWIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0E5</accession>
    <name>A0A2G4F0E5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55223">
        <property type="protein sequence ID" value="PHX55223"/>
        <property type="gene ID" value="CP500_011835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="19797" checksum="626D314EB2AB9AA0" modified="2018-01-31" version="1">MALYTASSFKSELNDKGWRMTPQRETILHVFQNLPKGNHLSAEDLYTLLKNRGENISLSTIYRTLKLMARMSLLRELELAEGHKHYEINQPYPHHHHHLVCVQCNRTIEFNNDSILKIGMKQAEKSGLHLLDCQLTIHTVCHEALRMGWPSLVSSNWSCPRSIAENGNAPDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0J3</accession>
    <name>A0A2G4F0J3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55281">
        <property type="protein sequence ID" value="PHX55281"/>
        <property type="gene ID" value="CP500_011585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="12141" checksum="691B956756A53938" modified="2018-01-31" version="1">MRYVFHPAALTEYAQAVEFYTERRVELAQAFINAVEDAIFRLIESPTRWPIVDEDIRRCLTRKFPYGILYTIEDDFILIVAVMHCNREPGYWKERVTDKPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0K0</accession>
    <name>A0A2G4F0K0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55283">
        <property type="protein sequence ID" value="PHX55283"/>
        <property type="gene ID" value="CP500_011595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="778" mass="88189" checksum="4881B8E5D0DE12CF" modified="2018-01-31" version="1">MQLKNRIEDYLETIKPDTAGITCPACGSVLGIRRQGSTDMVLTQNVRLELDGNLNSYRLFLEKIEAILEQRTVYYKGYAGNYPYDRELRHYQRGEKLQIEFKPDGNYTGIIAELVSNSFVEMIDFFEWIKNFYSFPRVDKDKSLNQMNGEEAKLIYQKTKGILVTGLEPRSIAGPLVDIIFDQKYVSTWQQKVLKNPENMNKLAKLLEEICPAIDWYLKILMDINSKNPDNQTNPQNHEQLKDGITRIKFILAIVLGHRTQNNELLTDLFIEADSPFTLPRKTVIAPKYLGQLLCSEIVLGNCKIGLSQNLLQKLKKELNNGQRQGNDKTVEEVVKNLNNEIDKFVHFCCSGPVSKNPDQKSEDSRDLSKTAYIFAEENCGWYPKLEPTHPVILLGSPGTGKSSVMLTGFTTFYENIYALGATINFESPEDEARMNSLYKDYSAGIMPKPTSKGDRTTIKLSIEFPVKGYPRTHFVFTDVAGEVMARSLTAEGSDPAILRILKNAETIIFFFDISIEPSIRQKLTEGDDGTWQKLDKSVKRVFVSRANNQQNVKDTSRAEVSQIQLLGKLIQDLRVQRGENDLKNDGVNFICVIPKMDLFADETEGDRYFFTKFLKDLQLQDILVRSHRGNEDESFQGMRSIGGTSAKIPDQTSRKLIPDNGIEDQKILGQWISQKTLTYLSKVKQALDPQTPEPIKDSLQYTLDVGLVKTLNYNFGEDNVYFLPVSAQGKDSDNLNFGSAPNQKLSEYVFILPVVLSINNNGQSSEEQNKKSGFPWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0L0</accession>
    <name>A0A2G4F0L0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55293">
        <property type="protein sequence ID" value="PHX55293"/>
        <property type="gene ID" value="CP500_011660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_12" evidence="2">
        <location>
            <begin position="86"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="395"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="499" mass="57352" checksum="E15C445F8D78EF70" modified="2018-01-31" version="1">MTNIYVDMLENPVIKALIREQAKFPEDFKLNICEDDEMYLFALGNVKDDRDRALVRYYSLGRRILDTVKQIVDWHFGSFENVPCFLDFACGYGRFTRFLIQEIPPERIWVSDISTKAVKFQTEYFGVNGIVSTGNPENFLVDRKFDCIVVNSFFSHMPERTFSNWLENLYNLLTPNGILIFSVHDECLRAPGAEMPAKGILFSPNSEIQSLDKAEYGTTYVSEKFVREIVDKVSSSKAFVHRIEKGLCRFQDLYIVTNQLVKDFSSLKFNHHPEGYVDVAAFTNKGNLYLEGWAIDANQDGSIEEVQVLVNGKIVQRCEPFYDRLDIDIHFQKDAISPSGWSCYLAKDTVSTEDVLTVKLINNYGGKLIIENCTVQSLVSQKLSQSLLGSTHEKLNLVETQLASAKIQLEQSQHDLNSTQVQLQETQTQLVNERTQLEQTQVNLISVQRHLEETEKYLIHVKEEVERSQNRIQAMETSKFWQLRTAWFKVRRALGLAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0P0</accession>
    <name>A0A2G4F0P0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55334">
        <property type="protein sequence ID" value="PHX55334"/>
        <property type="gene ID" value="CP500_011355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="45"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="153" mass="16452" checksum="025C718C7EE0A27F" modified="2018-01-31" version="1">MIVNPENVAESTGSNYPRQFKSAVAGRVKKRLGNAAGLKNFGVNLVRLVPGSCSALRHWHSCQDEFIYVLEGEVTLVTNSGEQVLKSGMAAGFPAGDADGHHLVNPTDSDVVYLEIGDRTDGDSANYPDDDLIANASANGWIFTHKNGEVYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0P9</accession>
    <name>A0A2G4F0P9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55330">
        <property type="protein sequence ID" value="PHX55330"/>
        <property type="gene ID" value="CP500_011335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8658" checksum="B752351673A53434" modified="2018-01-31" version="1">MMTLQEIIDQVQSLSIEDQDQLFEFIRKRRIENRRAEILANAQEVMQAFKDGTAKRGSVDDLIADLLGDDDGSCLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0W8</accession>
    <name>A0A2G4F0W8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55396">
        <property type="protein sequence ID" value="PHX55396"/>
        <property type="gene ID" value="CP500_011015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022573">
        <property type="entry name" value="DUF2887"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11103">
        <property type="entry name" value="DUF2887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="218"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="283" mass="32460" checksum="A0C1829FB84A8A15" modified="2018-01-31" version="1">MRRDSIFYKLFGQAPTLLFDLLATTPANAANYRFDSVAVKEPKFEIDGVFLPPESEEPGIVYFCEVQFQKDEQLYERLFGESFLYFYRNRSRYSDWQAVVIYPSRSVEQSDVYPYRALLNSNQVHRVCLDELGDIRALPLGIALMVLTTVGETQAPAEARYLLSRVQQEVPPAAGRDIIDLLATIMSYKFTSLSRAEVESMLGITLQETRFYQEAKAEGRQAEACALIVRQLTRRLRQEISEEMRSRLANLPLLVLEDLSEALLDFATMADLQAWLEVQQSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F109</accession>
    <name>A0A2G4F109_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55435">
        <property type="protein sequence ID" value="PHX55435"/>
        <property type="gene ID" value="CP500_010865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8401" checksum="57A62947D44BA847" modified="2018-01-31" version="1">MTQEQNQHPQVNLGKSSENTELEQANVSAEELPVNVKLKTSSQAFVASGEDRLKALARLMIVRFAWSMAEISQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F163</accession>
    <name>A0A2G4F163_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rfbD</name>
        <name evidence="4" type="ORF">CP500_010675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55478">
        <property type="protein sequence ID" value="PHX55478"/>
        <property type="gene ID" value="CP500_010675"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01214">
        <property type="entry name" value="rmlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="3">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="290" mass="31699" checksum="6AD6F2DBC3E46F59" modified="2018-01-31" version="1">MKILLTGSNGQLAQELHPILLSLGEVIAVDRTRLDLSQPESIRQVIAEIQPDLVVNSGAYTAVDKAESEPELAYSVNGVAPGIIAEECEKLGSTLIHISTDYVFDGSQGSPYKETDATNPLGIYGKSKLAGEEAIRQAGNRHIIIRTAWVYGNSGKGNFVKTMLRLGKDREEIRVVADQIGSPTWTGDLAAAISQIIPQIKPELFGTYQYTNSGVCSWYDFAIAIFEEAEKLGCPLKIQRVIPITTSEYPTPAKRPAFSVLSAVKISGILSTHPPYWRQGLRQMLAREVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F169</accession>
    <name>A0A2G4F169_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55495">
        <property type="protein sequence ID" value="PHX55495"/>
        <property type="gene ID" value="CP500_010330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008886">
        <property type="entry name" value="UPF0227/Esterase_YqiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05728">
        <property type="entry name" value="UPF0227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="229" mass="26481" checksum="119B469C09F049A6" modified="2018-01-31" version="1">MKLSQNSSYIYLHGFASSPDSLKAKYFCDRFSSLAIDLKTPDLNQNDFSRLTLTRQLNQVETAFFQPQTLDYQVENVENPVEVTIIGSSFGGLTAAWLAQRQISVKQIVLLAPAFDFLGYWLPMLGQQQLEKWQSEEYLPVYHSREQRDLPLNYQFVADLAQYPEEKLMRSVPTLIMHGLHDTIIPIRASRNFAANRPWVQLIELEDDHSLGNFLAEIWEAIQKFCQFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1B5</accession>
    <name>A0A2G4F1B5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55528">
        <property type="protein sequence ID" value="PHX55528"/>
        <property type="gene ID" value="CP500_010510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_9" evidence="1">
        <location>
            <begin position="3"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="94" mass="10568" checksum="7E171185736626B0" modified="2018-01-31" version="1">MPKAIWNGAVLAESDKCEVVDNNYYFPADTIKREFFKDSSTHTTCGWKGVASYYSIEVAGEVNKDAAWYYPTPKDAAKNIEGYIAFWKGVKVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1E4</accession>
    <name>A0A2G4F1E4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55580">
        <property type="protein sequence ID" value="PHX55580"/>
        <property type="gene ID" value="CP500_010140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7685" checksum="FBC82C79AF02012E" modified="2018-01-31" version="1">MQTITITIPDDRLHKLQETANRLGISLEALLLAGAENLLAPPETSFHNAMEYVLKKNAVLYQKLVLPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1E6</accession>
    <name>A0A2G4F1E6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribonuclease Z</fullName>
            <shortName evidence="8">RNase Z</shortName>
            <ecNumber evidence="8">3.1.26.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">tRNA 3 endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNase Z</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rnz</name>
        <name evidence="10" type="ORF">CP500_011615</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55287">
        <property type="protein sequence ID" value="PHX55287"/>
        <property type="gene ID" value="CP500_011615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07717">
        <property type="entry name" value="RNaseZ_ZiPD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02651">
        <property type="entry name" value="RNase_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="9">
        <location>
            <begin position="18"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="312" mass="34758" checksum="5E0BD487ED63DD68" modified="2018-01-31" version="1">MQITFLGTSSGVPTRSRNVSSIALRLPQRAELWLFDCGEGTQHQFLRSELKVSQLSRIFITHLHGDHIFGLMGLLASCGLAGNVKRIDIYGPPGLEEYLQAGVRYSQTHFSYPVKVHKSHEGVIYEDDEYIVSCAPLKHRVTAFGYRVTEKDRPGHFDVEKAKAVGIPWGPLYGQLKQGKTVQLSDGREFKGTNFCGPDQVGRKFVYCTDTVFCDSAVELAKDADLLVHEATFAHQDAQMAFDRLHSTSTMAAQVALMAGAKQLIMTHFSPRYAPGNAIVLDDLLKEAQAIFPNTKMAYDFLTYEVPRPVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1L7</accession>
    <name>A0A2G4F1L7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55664">
        <property type="protein sequence ID" value="PHX55664"/>
        <property type="gene ID" value="CP500_009650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="229" mass="25601" checksum="BD19CFCB18DB8237" modified="2018-01-31" version="1">MHSAKQIGSILLYFLGAIGYLAIAVVIVGTSVLIKFVALMLADKILYTILILGDLLRGIEIIELLNLLVFAFIGMGFGLATRLLKPEYGRKVSAILLTAIVPLVFMSTPIIRYNSWLDKVEESDNLSRAETTTLTNSFLKKQVGIQGFLGYYFYTGQFPVIPTKQSEMKDLDSFEKKINSKFVQLTGAAPTIVSWSMLICFWVIRIFYFSIAVIATIAHFRQGVVIARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1T0</accession>
    <name>A0A2G4F1T0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55437">
        <property type="protein sequence ID" value="PHX55437"/>
        <property type="gene ID" value="CP500_010875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013545372" evidence="2">
        <location>
            <begin position="24"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="257" mass="26644" checksum="71051A630FFE906D" modified="2018-01-31" version="1">MKLRIILVATVLSALAPVAPASAENVQHTQQLLATRQCPNCDLNGAGLVLANLTGADLKGADLRGANLSRANLAGADLSGANLSGTSLFGVNLTGANLSGANLSGADLRSAYLSNANLLNTNLTNAQLLGIRGMPTNIGTAEDFYKLGVIEAQAGNYRNAIDYYNQALNLKPDLAAVYFARSMSRADLGDFAGATQDAGIANKLFTAQGSVQGQELSKQLTEAIVARQKPTEPRTGGGGDFMSLLGSLSSFLLQVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F208</accession>
    <name>A0A2G4F208_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55786">
        <property type="protein sequence ID" value="PHX55786"/>
        <property type="gene ID" value="CP500_008845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="199" mass="22252" checksum="8FEB41C074E65274" modified="2018-01-31" version="1">MPYSQFSIEQIKTNFGITLTRTVGLFAGIPEIEPSNFLKETLQFNLPLALEINSEKARSELIVAPILVELKKRLPERMSLFSGREFNVDAARGLSGYCDFLISRSPEQLVIESPVIALVEAKNDNIQSGLGQCIAETIAAQIFNQRQENDIQTIYGVVTTGSIWKFFKLEGIAIEMDTNEYFINNVGKILGILINFIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2I7</accession>
    <name>A0A2G4F2I7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe-S cluster assembly protein SufD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufD</name>
        <name evidence="3" type="ORF">CP500_008090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55955">
        <property type="protein sequence ID" value="PHX55955"/>
        <property type="gene ID" value="CP500_008090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PTHR43575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="28"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="439" mass="47680" checksum="80F3256BD24A0E2A" modified="2018-01-31" version="1">MNTQVATREMFLAGLVNQCEKLGEANGKSSAYGLDDLRDIATQYVLAASFPTVKDEEWRFTDLSSLLQIPFHVPQDNQSAIQLSDITMPVKNKDDLPLRLVFVNGVYAPDLSAVNLPDFYVGNLSNAPEKYQARIADVLSKHRQPNEVFTALNVAGLVDSAVVFVPANRSLDTPIHLLFLTAPGASPMMCQPHCVIIAEPGSNVTLVEDYATIGNVAAFTNAVTDVVVGENAAVNHVRLQREAGNVVHIGKSAIAQSRNSRYTCHAISLGAKISRHNLEVFQHGEATETTLNGLTVAFGEQLSDTHSLISFNHPHGTSRQLHKCIIGNKARAVFNGKVFVPKAAQLTDAGQLSRNLLLSSRARVDTKPQLEIVADNVKCSHGATVSQLEDDELFYLQSRGLDLERSRYLLIDAFAGEILDKLPIVGVAKMLSTCMAIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2K1</accession>
    <name>A0A2G4F2K1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55972">
        <property type="protein sequence ID" value="PHX55972"/>
        <property type="gene ID" value="CP500_007970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="12380" checksum="6707028AEFF83CD3" modified="2018-01-31" version="1">MATQNQILEQLKILEALYNRGEVSEVVELSLSKIIAHEIAIAQQQATELETDLQQFETHYEMSSPEFYQKFRAGELGDDIDFVEWSSFYQMSCSVGERLQILLSNSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2U8</accession>
    <name>A0A2G4F2U8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF1957 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_007235</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 57 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56091">
        <property type="protein sequence ID" value="PHX56091"/>
        <property type="gene ID" value="CP500_007235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030979">
        <property type="term" value="P:alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037090">
        <property type="entry name" value="57_glycoside_trans_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015293">
        <property type="entry name" value="BE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040042">
        <property type="entry name" value="Branching_enz_MT3115-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004300">
        <property type="entry name" value="Glyco_hydro_57_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41695">
        <property type="entry name" value="PTHR41695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09210">
        <property type="entry name" value="DUF1957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03065">
        <property type="entry name" value="Glyco_hydro_57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="SSF88688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_57" evidence="3">
        <location>
            <begin position="7"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1957" evidence="4">
        <location>
            <begin position="427"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="529" mass="62069" checksum="FA0279CF69946450" modified="2018-01-31" version="1">MTTGYLALVLHAHLPFVRHPESDYVLEEEWLFEAIAETYIPLLQVFEGLLRDGIDFKITMSMTPPLVAMLRDPLLQDRFDEHLAKLEELIELEMVHNAGNGHLRYLAEHYATHFSQVRNFWEKCDRDLVKAFKQHQDTNNLEIITCGATHGYLPLMKMYPEAVWAQIQVACDNYEANFGRRPKGIWLPECAYYEGLERMLADAGLRYFLTDGHGILYARPRPRYGSYAPIFTESGVAVFGRDHESSQQVWSSEVGYPGAAEYREFYKDLGWEADYDYIKPYIMPNGQRKNTGIKYHKITGRGLGLGDKQLYDPYWAREKAAEHASNFAFNRERQVEHLNGIMQRPPIIVSPYDAELFGHWWYEGPWFLDYLFRKSWFDQNTYEMTHLADYLRGNPTQQVCRPSQSSWGYRGFHEYWLNETNTWIYPHLHKAAERMIELGSMEPEDELQLRALNQAAREVLLAQSSDWAFIMRTGTMVPYAVRRTRSHLMRFHKLYDEVKEGKVDSGWLGKVEEIDNIFPEIDYRVYRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2X6</accession>
    <name>A0A2G4F2X6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AHJR-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56095">
        <property type="protein sequence ID" value="PHX56095"/>
        <property type="gene ID" value="CP500_007255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040902">
        <property type="entry name" value="AHJR-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18743">
        <property type="entry name" value="AHJR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AHJR-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="222" mass="25550" checksum="ED1843657F5641BB" modified="2018-01-31" version="1">MNAKLIHDKSVSKIAEKYRQEGYTVLVDPEPADIPFDLGTYRPNLIVKKNEAEGYIIEFKRSARQTSIDRLKEIAEIVSENTGWRFLLITEDALLKDEDNEVNLLSWEQVFSRKTQGERLISLGENEGAFLSLWGTIEALLRRRAEEVTIPIERFPTLSLIKHMYSQGELSIEEYDRAMLLLSVRNRFIHGFQTPEINESVSELLVLVNELISLWAPSISLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2X9</accession>
    <name>A0A2G4F2X9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ImmA/IrrE family metallo-endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56112">
        <property type="protein sequence ID" value="PHX56112"/>
        <property type="gene ID" value="CP500_007345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010359">
        <property type="entry name" value="IrrE_HExxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06114">
        <property type="entry name" value="Peptidase_M78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M78" evidence="1">
        <location>
            <begin position="86"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="229" mass="26041" checksum="9EBEE899A2158447" modified="2018-01-31" version="1">MSIFKPYCFYPKESIEGLANDILMRMQKTQNFAPKWPIDATTVADFLDLGVVWELIEPDEEGAIAARILPQQRLIEINEQILEKPPGFIESTIAHEIGHWVLHINQDEADGVVEQLELNLENGGNTAQDVEEPFVCRGASADTKVASIEWQAQYFASCLLMPRCILEDKRQGRDLTKWSHLYKMRDELGVSISNLTNRLQEFGWIYIPKGTREIYAGKDAANGQQRLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Z4</accession>
    <name>A0A2G4F2Z4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56108">
        <property type="protein sequence ID" value="PHX56108"/>
        <property type="gene ID" value="CP500_007320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="325" mass="37441" checksum="F1ED804A063E415A" modified="2018-01-31" version="1">MTLGTAKESKAKILQNFQQILAENKKIESKVETKEQEAEKAKNKQLLEVASTYTVDSIVKGLADLQLDFGSVINGLSERLSAEASKLDELKRGIEIETAQLQQLQRIRVVADALYILTQEHQEKITALEQSAASQREVIEKDTIQKRKIWEKEQQEFDIIVQERTALIIKEREQETADYRYELERTRTVATDEYEETKRKLERELQQSTREKEKNWVEREKVLSDNQAQFAENQTKAAGFEEELKQAYIKAKEEAIQEVSREAKVKADLVDKEWEGTKQGYELKVQSLQQNIGRQAEQIAEISAQLQATMKQSQDLAMKAFASKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3H1</accession>
    <name>A0A2G4F3H1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5 8">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">clpP</name>
        <name evidence="11" type="ORF">CP500_007695</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 9">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 10">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5 8"/>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56027">
        <property type="protein sequence ID" value="PHX56027"/>
        <property type="gene ID" value="CP500_007695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0720">Serine protease</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="197" mass="21936" checksum="61CFA38CA5313F93" modified="2018-01-31" version="1">MPIGVPKVPYKMPGGYDTQWINIYDRLYRERIIFLGRDVDDEIANQIIAVMLYLDSEDSGKDIILYINSPGGSVTAGMAIFDTMQHIKSDVVTICVGLAASMGSFLLAAGAKGKRLALPHSRIMIHQPSGGARGQATDIQIEAKEILRLRHQLNGIYAKNTGKPIEKIEKDMDRDYFMSADEAMEYGLIDRVIDERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3L5</accession>
    <name>A0A2G4F3L5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CdiI_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56325">
        <property type="protein sequence ID" value="PHX56325"/>
        <property type="gene ID" value="CP500_005940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041129">
        <property type="entry name" value="CdiI_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18593">
        <property type="entry name" value="CdiI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CdiI_2" evidence="1">
        <location>
            <begin position="4"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="100" mass="11515" checksum="FC62B4A90BCDADAC" modified="2018-01-31" version="1">MNNQFPNLTQFFSSYFHQDWPLEASNASEVVKNYRHSESPESVEAALAELNKLLEMSIAPADLETFILEELGCYYNPEADNQTVTEWLQSVQHYLKNLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3N0</accession>
    <name>A0A2G4F3N0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 12" type="primary">pgk</name>
        <name evidence="12" type="ORF">CP500_005835</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56362">
        <property type="protein sequence ID" value="PHX56362"/>
        <property type="gene ID" value="CP500_005835"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="24"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="62"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="355"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX56362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="399" mass="42263" checksum="5437F6C96A151AB5" modified="2018-01-31" version="1">MTKKTLANLSASDLSGKRVLVRADFNVPLDNGSITDDTRIRAALPTIQDLASKGAKVILCSHFGRPKGVTEKLRLTPVAKRLSELLGKEVKKTDDCIGDEVAATVEAMQEGDVILLENVRFYPEEEANDPEFAKKLASVADLYVNDAFGTAHRAHASTEGVTKYLSPSVAGFLMEKELQYLGSAIDNPQRPLAAIIGGSKVSSKIGVIEKLLEKCDKLLLGGGMVFTFYKARGLNVGKSLVEDDKLELAESLEAKAKERGVTFLLPTDVIVADKFAADANTQIVSVENIPDGWMGLDIGPDSVKTFQAALADCKTVIWNGPMGVFEMEKFAAGTEGIAHSLAEITKTGTTTIIGGGDSVAAVEQLNLGAEMSHISTGGGASLELLEGKELPGVAALDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3N7</accession>
    <name>A0A2G4F3N7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56393">
        <property type="protein sequence ID" value="PHX56393"/>
        <property type="gene ID" value="CP500_005625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8359" checksum="89092A2508AE83FC" modified="2018-01-31" version="1">MSNISISLPDDLLTYVNQKARNPSALIESLLKQWRKQQENQALAEACKLIDELDLGWDEEWQAQAITDWEVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3T8</accession>
    <name>A0A2G4F3T8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56408">
        <property type="protein sequence ID" value="PHX56408"/>
        <property type="gene ID" value="CP500_005710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="216" mass="23670" checksum="69B9A192BF9F0FAF" modified="2018-01-31" version="1">MESIIKILLGSLALSMIHALIPNHWMPLIAIGKTENWSRSETLRATVITGVAHTLSIILIGIVVGLFGYKFAATYVEAAKIIAPLVLLVLGIIYLLAELDSSRKQHHHHHVETANLTTKRSQFQILAVLGTGMFFSPCIEIEAYYFSAGTIGWVGILVVSVVYLVVTVLGMVLLVDFGMKGVNALEEKLHFFEDHEQGLTGAMLIVLAVVAYFIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Y4</accession>
    <name>A0A2G4F3Y4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56445">
        <property type="protein sequence ID" value="PHX56445"/>
        <property type="gene ID" value="CP500_005435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="235" mass="25213" checksum="4767D0281FFE49AC" modified="2018-01-31" version="1">MQNKVVVIVGATGGIGSAVARKLADAGANLVLAARDSSRLDALATQLPTTEILAVPTDITQLPQVETLMQKALEHFGQIDVLINAAGAGILKQWNKLEPADLDAMLDLNLKGSFYTSQAAANVMKDRKSGHICNVIGILGKHSMAMGTAYCASKFGVVGFSKCMADELRRYGVKFTLFYFGGVDSPFWDNVSLKVDRSKMLSTETAANAIMFALSADPQAVPMEINIQPESHLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F436</accession>
    <name>A0A2G4F436_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56481">
        <property type="protein sequence ID" value="PHX56481"/>
        <property type="gene ID" value="CP500_005170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="29055" checksum="8E293D33CA053342" modified="2018-01-31" version="1">MWSCPRSRSTAITRAFEQLDECVVYDEPFYSAYLAIKGQDNYPPIQPEELSKYKDTDYNAIIQKITGELPNGASFSFQKHQSKHILPEFGRDWIEQLNNLFLIRNPKETIFSYWKANQFQGELNMEKLGLLQHYNLFQEIKNLTQKTPLIIDANDLVLSPKNYLNLICTNFEVDFSEKMLTWEANPSKTALSWTKETPYYHWYSNVLNSSNFTYQKTEINFPEELTPLLELCTPIYEELFRQRAVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F444</accession>
    <name>A0A2G4F444_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3122 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56516">
        <property type="protein sequence ID" value="PHX56516"/>
        <property type="gene ID" value="CP500_005020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021469">
        <property type="entry name" value="DUF3122"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11320">
        <property type="entry name" value="DUF3122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="19452" checksum="BF3EE7D01F8F4CD2" modified="2018-01-31" version="1">MNPICFFNAAKIRLMRRLMAAFICVLLIVCIPLPAFATAGQIEEYPGQMLYQSRQKLHDQNGKSWLAIAFKRIHPDGSAIVSLRLVGFPGGVEFDRTQPLTLTTSLGQTLTAKDISSEISHDTPAPSNVGEYDIQLALPQLQAEIPLQLTLPTIDGESVRLSVPSAAIQEWQTLISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F491</accession>
    <name>A0A2G4F491_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56531">
        <property type="protein sequence ID" value="PHX56531"/>
        <property type="gene ID" value="CP500_004995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035223">
        <property type="entry name" value="DUF5335"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17269">
        <property type="entry name" value="DUF5335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="117" mass="12759" checksum="61879E42E31ED33B" modified="2018-01-31" version="1">MTNKIEINKSVPRERWGEFFDQFTDGNRGRHISIAIIGSELGDAELIKNAPLMAMVYDRPGKGDDLVIEVGKDEVNYAHTVDSPTEVLTGQNSNGVMVALRISDAAGTQTLIQLQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4A9</accession>
    <name>A0A2G4F4A9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_004220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56624">
        <property type="protein sequence ID" value="PHX56624"/>
        <property type="gene ID" value="CP500_004220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014324">
        <property type="entry name" value="ABC_heterocyst_DevA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02982">
        <property type="entry name" value="heterocyst_DevA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="18"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="242" mass="26482" checksum="98C03CC7DF057A60" modified="2018-01-31" version="1">MQTLNIPAEKNTATEPVISVKNLNHYFGSGALKKQALFDINLDINPGEIVIMTGPSGSGKTTLLTMLGGLRSAQDGSLKILGQEIRGASTNKLTKLRKQIGYIFQAHNLMTFLTAKQNVRMSLELHKEMLNQNMDALSIAMLEAVGLGDRANYYPENLSGGQKQRVAIARALVSHPKIVLADEPTAALDKKSGRDVVEIMQTLAKEQGCTILLVTHDNRILDIADRIIYMEDGRLVTNLADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4B7</accession>
    <name>A0A2G4F4B7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56589">
        <property type="protein sequence ID" value="PHX56589"/>
        <property type="gene ID" value="CP500_004890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="42"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="246" mass="27559" checksum="B112A6D3A7089364" modified="2018-01-31" version="1">MSPVSAALGEDRTLLISRCLLAGLGTRMFLHQENRIPQESPVLVVSNHRSFLDPVLLTAALGRSIRFACHHYMGQVPVVRELVTSFGAFPLKKPEHRQQHFFDQATALLQNREMVGVFPEGAEPMVNFTQPQTVGKFQRGFAHLALRASVRDLVVLPIAISSFEEQSVRSGLPLKLLSLFDPSEPLFDRPGWHPVIVYKRVNVFVGRPYWITGDRKQQYRGKQAKAVVAELTEHCQGEIAQLLQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4C4</accession>
    <name>A0A2G4F4C4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Ferredoxin-thioredoxin reductase, catalytic chain</fullName>
            <shortName evidence="15">FTR-C</shortName>
            <ecNumber evidence="4 15">1.8.7.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 15">Ferredoxin-thioredoxin reductase subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CP500_004570</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 15">Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>[thioredoxin]-disulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = [thioredoxin]-dithiol + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:42336"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.7.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="15 17">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13 15">Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the ferredoxin thioredoxin reductase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.7.2" evidence="4 15"/>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56612">
        <property type="protein sequence ID" value="PHX56612"/>
        <property type="gene ID" value="CP500_004570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103012">
        <property type="term" value="F:ferredoxin-thioredoxin reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016730">
        <property type="term" value="F:oxidoreductase activity, acting on iron-sulfur proteins as donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004209">
        <property type="entry name" value="FTR_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024707">
        <property type="entry name" value="FTR_bsu_Cyanobacter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036644">
        <property type="entry name" value="FTR_bsu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35113">
        <property type="entry name" value="PTHR35113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02943">
        <property type="entry name" value="FeThRed_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000260">
        <property type="entry name" value="FTRc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57662">
        <property type="entry name" value="SSF57662"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15 17" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11 19" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 15 17" id="KW-0408">Iron</keyword>
    <keyword evidence="10 15 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 15 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="16">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="site" description="Increases the nucleophilicity of the active site Cys" evidence="18">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="19">
        <location>
            <begin position="65"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000260-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000260-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000260-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR000260-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="PHX56612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="124" mass="14056" checksum="E9049F3968DB2078" modified="2018-01-31" version="1">MNTTENTTEKSKLSKEKTLEAMKNFSETYAKLTGTYFCSELSVTAVVIEGLAKNKDELGAPLCPCRHYEDKEAEVKAAYWNCPCIPMRERKECHCMLFLTPDNDFAGTNQEIGMDQLQAVRETM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4G1</accession>
    <name>A0A2G4F4G1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid oxidation protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56673">
        <property type="protein sequence ID" value="PHX56673"/>
        <property type="gene ID" value="CP500_004045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="15855" checksum="FA57A8A220BFD47F" modified="2018-01-31" version="1">MSAKDVFHEVVKTALQKEGWRITHDPFQISVGGVDMSIDLGAEKLIAAERQGEKIAVEVKSFLAKSSPISEFHRALGQFINYRAALKQKEGDRILYLAVPLITYEEFFQLEFPKARVEENQVKMIVYDIANEAIVQWKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4H7</accession>
    <name>A0A2G4F4H7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein adenylyltransferase SelO</fullName>
            <ecNumber evidence="9">2.7.7.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">selO</name>
        <name evidence="10" type="ORF">CP500_005590</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-seryl-[protein] = 3-O-(5'-adenylyl)-L-seryl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:58120"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:15073"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:142516"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-threonyl-[protein] = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54292"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13847"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138113"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-tyrosyl-[protein] = diphosphate + O-(5'-adenylyl)-L-tyrosyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:13846"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.n1" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56387">
        <property type="protein sequence ID" value="PHX56387"/>
        <property type="gene ID" value="CP500_005590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="89"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="124"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="475" mass="54664" checksum="F3C9C1A04EF561A4" modified="2018-01-31" version="1">MSNPLLSLNYEPAIESLGGDYFDEVPAADFPQHILRFRNDQLLPKLGLDPSQVTDEHFTQAFGEFHCVRPFLALRYHGYQFNEYNPNLGDGRGFLYGQVRGTDGRLYDFGTKGSGRTPYSRSADGRLTLKGGVREVLAAEALHRLGVRTSRCFSLVETGESLWRGDEPSPTRSSVMVRFSHSHIRFGTFERLHYLRRPDLITKLLDFVIEYYYPELHLKASNTDIYQAEKYVLFYAELVKKVAELVAQWMAAGFCHAVLNTDNMSITGESFDYGPFAFIPTYDPKFIAAYFDYYGLYCYGNQPFICKGNLEKLQQPLAMAIPQADLDAALTKFGEYYNTAYRQLMLNRLGFDDLPEADADELLKLTIKLLAESQVDYQGFFFELRKQFDRTWRDDASKIFSEAEPTDSMAHWREFYCHVLQTLSADDLDKMADRLRQHNPGQSLLRPTIEAVWEQIAVEDNWEPFYALVKQLQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4I4</accession>
    <name>A0A2G4F4I4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2079 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56621">
        <property type="protein sequence ID" value="PHX56621"/>
        <property type="gene ID" value="CP500_004565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018650">
        <property type="entry name" value="STSV1_Orf64"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09852">
        <property type="entry name" value="DUF2079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="483" mass="54795" checksum="C81901CCE15F2153" modified="2018-01-31" version="1">MNKINYFQYCKSHRVVWGVALFSLIFFLCSSLRHSWLQSNAFELGIYDQVAYLISQGQTPFSSFLDIHHMGNHAAWVMYPVALLYKIYPDVHWLLLVQAVSLALGALPSWSLARQAGLNHSISWAIACTYLLYPLVFNVNLFDFHPEVIALPALLAAILAARLNKTLWFCAAILLVLSCKAVLSLTVAAMGLWLLFFEKNRNCGLVALFLGAGWFLIATQGVIPYFNQGREHAGIGRYQYLGKSVLEIAANLILKPHLILGRLFSLDTFEYLAFLVFPVIWWISPRHLTPLISAVPMLGMNILSDIPAQRDLIHQYSIPILPFLLVAAIANLSHQNLQEVKIPKIFDNLRIPSLPLSKAIVTWSFITFLCLAKYGYFWTIYLNETETLSATKEAITLVQTKGNVLTTSHIAPHLTHRPVVKLTQADTPPGNLTEFEYVLLNLRYPGWMSDRNFVQNLITQLTNNPQFQLKYQRDDISLFTKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4P5</accession>
    <name>A0A2G4F4P5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56742">
        <property type="protein sequence ID" value="PHX56742"/>
        <property type="gene ID" value="CP500_003790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12844" checksum="92BE0185446621EF" modified="2018-01-31" version="1">MERLDYRQLVQKVIHQHATEQSEQDVETTEIVFDTDRDRYLLLYVGWQDEERIHGCPIHVDIKDGKIWIQRDFTEAGIANQLLELGVPQTDIVLGFRAPYVRQFTGFAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4P8</accession>
    <name>A0A2G4F4P8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CsbD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56730">
        <property type="protein sequence ID" value="PHX56730"/>
        <property type="gene ID" value="CP500_003725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD" evidence="3">
        <location>
            <begin position="5"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="6508" checksum="C91344807B67A9E2" modified="2018-01-31" version="1">MSIEDRAKATAKNVEGAAQETLGNVTGDPKDKAEGKAKQKQAETSHAVQDAKDAVKDVIDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4T6</accession>
    <name>A0A2G4F4T6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">trmD</name>
        <name evidence="17" type="ORF">CP500_004950</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 15">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="6 13 15"/>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56507">
        <property type="protein sequence ID" value="PHX56507"/>
        <property type="gene ID" value="CP500_004950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="16">
        <location>
            <begin position="22"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="131"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX56507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="231" mass="26029" checksum="A3058B2C8168F629" modified="2018-01-31" version="1">MRFDVVTLFPEFFLAPLGSGLMGKALAKNIAEVNFVNPRDFTTDKHHRVDDEPYGGGVGMLMKPEPIFAAVESLPILPRREVILLTPQGEPMQQGMFRGFAAECDQLVLICGHYEGVDDRVLDLVTREVSLGDFVLTGGEIPALALINGVLRLLRGTVGKEDSLKFESFEDGLLDYPQYTRPADFRGLKVPDVLLSGNHAEIARWRREQQIEKTRSRRLDLYEVWLQERGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4W7</accession>
    <name>A0A2G4F4W7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56751">
        <property type="protein sequence ID" value="PHX56751"/>
        <property type="gene ID" value="CP500_003835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8305" checksum="AA4F3425567E8D3B" modified="2018-01-31" version="1">MKMESNHELEDESRSEYDFSKMKGGVRGKYIDRYKAGTNIVLLDPDVALAFPTSDSVNEALRLLIQISQRQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4X2</accession>
    <name>A0A2G4F4X2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Polyketide_cyc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56788">
        <property type="protein sequence ID" value="PHX56788"/>
        <property type="gene ID" value="CP500_003395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polyketide_cyc" evidence="1">
        <location>
            <begin position="13"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="17234" checksum="BA498335E40DCE06" modified="2018-01-31" version="1">MTDWLEHSVQVEVEIPIELAWKLWSDLEQLPRWMKWIESVQILEDNPELSRWKLATGGLEFSWLSRIIKLVPNQIMQWESVDGLPNRGAVRFYDRKNSSIVKLTVAYGIPGWLAKLMDNSFVGRVVESTLQADLERFKEYALKVKATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Z1</accession>
    <name>A0A2G4F4Z1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56842">
        <property type="protein sequence ID" value="PHX56842"/>
        <property type="gene ID" value="CP500_003330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="9339" checksum="583672B7CC6EB1D2" modified="2018-01-31" version="1">MIAFRKLSIGLLRYILINHLLDRPTASNADQKQVELAIGKYYRMARLFRLLQLIGFCRTHICQELRAKATELVRNYKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F516</accession>
    <name>A0A2G4F516_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transmembrane sensor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56829">
        <property type="protein sequence ID" value="PHX56829"/>
        <property type="gene ID" value="CP500_003260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007890">
        <property type="entry name" value="CHASE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05226">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01080">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="702"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="730"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="756"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE2" evidence="2">
        <location>
            <begin position="408"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="784" mass="89147" checksum="DF962B48D67DACE0" modified="2018-01-31" version="1">MSKLVILEIRNLDRDQRYPVTLRIGDSINSMNVSTHGYLPPAQDLKKSYDHFNTCRRDCNLGRSRKLEHINKGKIVHYSIKELGDTLENNINTWLTFGDRDFHPIRDKIIEVLSHENAKHQGKSKVRFIIQTDDVDLWGLPWHLWEKFQQFEVEPVISSFQAISNTQLISPQDKIRVLVILGASKGIDILVDLKSLEEFIDPNEAEIIPLVAINSSKLNDELWKQNWDILFFAGHSSSTDDYSQGKLALSETESISIKDLKYGLENAIKHGLKLAIFNSCDGMGLVNELASLQIPAVIAMRELVPDEVAQNFLKYFLQAFAREKKSLPDSVLQARKKLHGMEGEYPFASWLPMIYEHLAVESPTWDELLRGNEEERQRVSIWRNLRTVLVASVLVTGAVMGVRWMGLLESLELPAYDHLMWQRQSEAIDPRLLVVEITGSDLDKYGNPVKDATVAKLIEKIEQNEPRAIGLTLHRYQPQQPGREALIAQFKNSNLLGVCAFGDGNQKGYPPASELSEKQIKDQIGFSDLQIDDRHDNNGRMVRRQLLSYNPQRFPSSCPSPFSLSLKLAYRFIYGENIQPITQENDKWRFGKIILQPLGSQTGGYQKLGESDQILLNYRANPMPAQKVTLTEVIEGRVSRNLIKDKIVLIGVNDPRGKEEVDTPYGRMATVWVHAHMVSQILSAVIDKPNRPLLWVLPQWSFIQWGDTVFIWVFALSGGLLVWRFRSPLQLILATGLATCIIYYLCLAILHRGGWMPLVPSVLALFTTGGTLVLYTVSREQKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5E2</accession>
    <name>A0A2G4F5E2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56697">
        <property type="protein sequence ID" value="PHX56697"/>
        <property type="gene ID" value="CP500_004190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="2">
        <location>
            <begin position="136"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="801"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="898" mass="100916" checksum="76C8F0908FCAB3B0" modified="2018-01-31" version="1">MIPSDIRLYTWVDVEQVLLRMQEQNKWPEWLVWARAYWDELTIGIRPGTQAQASAWLQDVYDPRYRLHSQPEIVQGLIILESLPESERTLPIFFEETEEQPPIPRLTPSLSRPGVLWQLCQDIERPDSLSSDVPPVVAFHSFKGGVGRTTHALALAQALTEDKHKVLLVDGDLEAPGISWVFERRLPNPSVSFADLIALVHGDASPDAVDAVQLVADRIQNALIDGIYVLPSFRSNEKFTALEIRPEHLFQSAKNPFILTNILASLGQALGADFVIVDLRAGLSELSTGLILDPRVYRIFVTTLSAQSISGTVRLLELLGERALSRRDTEPLPALIINQIPDQERSSDIVLEAETKLLEAASPFLGEGGEPVRVLTSFTDGLLVLPPTWEEVVTRLLRSGIVDAVRPLVEWLPVVQRSEPMGNPLSSLNSQREELSKIAKQLIFAENAEVNDFLATTPLRHLASDHRRRLPIAVIVGAKGSGKTYTFIQIVRRKNWQQFAIDAGAIDVQTNAVICPIIESINLQESAQNIVREVRINAAQVLGFEQPTDASSIRDYIREGYLLNLHEGEWRDRWLNVIAWGVGFDHTKTKSQQADTTIENAGRRLTESLALAKKQLVVVIDGLEDLFQNFASDRTQQTAIRSLLQDVPEWLGQQPSLPLGIIIFVRRDMVLAAVHQNPAQMMARYEPYALQWNREEALRLVAWVTNLAKILPGINITKLQDMSEVELTEALIPLWGKRLGSERSKEAGSARFTLAALSDFRGQIQARDLVRLLHLAAQSSVNDTRWEDRILIPTAIKGVLRECSSEKIQEIENENTSLKNVFAKLRNLRAENRKIPFTREMMELSVEEMKILEDNGVVIRENDEYYMPEIFRLGLGFSLTATGRPRIIALARRAGQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5F0</accession>
    <name>A0A2G4F5F0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">F-type ATPase subunit delta</fullName>
            <shortName evidence="6">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpH</name>
        <name evidence="6" type="synonym">atpD</name>
        <name evidence="7" type="ORF">CP500_002500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="6">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cellular thylakoid membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56976">
        <property type="protein sequence ID" value="PHX56976"/>
        <property type="gene ID" value="CP500_002500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="PTHR11910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="SSF47928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-0139">CF(1)</keyword>
    <keyword evidence="2 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="3 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="181" mass="19864" checksum="261CF4083D4D0F62" modified="2018-01-31" version="1">MSKVNTQVLQPYASALMSLAKSNNLSEEFGTEIRSLLGLLESSEDLRQFLGNPLIKPDAKKAVIKQIAGEDMNPLMRSFLSLLIDKGRILFLEGIGKQYLTQLRELNQTVLAEVTSAVPLSDAQQQTVREKVQAMTSARQVEIETKIDADLIGGVVIKVGSQVIDASLRGQLRRLGIRLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5H4</accession>
    <name>A0A2G4F5H4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56988">
        <property type="protein sequence ID" value="PHX56988"/>
        <property type="gene ID" value="CP500_002565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17629" checksum="165709D50355BC69" modified="2018-01-31" version="1">MNPKGDNEQSNPLRKLRNLPTTSKAQLIQNRETWLPRGEALAVDKAQEVMNDLYREGAEYGDGSCAFMVMKEQFEGGAGNPPQSLKDSTLHAGKCQQYIKGLRRHLAKLPSEAKPKIEQEIVKMEEALKWAEDYHNGDEPEIPRWAKPWKEQLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Y0</accession>
    <name>A0A2G4F5Y0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3'-5' exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57194">
        <property type="protein sequence ID" value="PHX57194"/>
        <property type="gene ID" value="CP500_001335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="1">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="430" mass="49523" checksum="0C142E0E4862E50B" modified="2018-01-31" version="1">MPYLTAANDIKALIAKFSQSRILWIDTEIADYISNPKLSLIQVLADPKDLTGDATFLLDLLDRPELVKEFIDKIMVNPNIEKVMHNANYDIRFLGNDDAQNITCTLNMARQIPYYILPLPDRKLKTLIEKICNIGYVDKTEQSGDWAKRPLTENQLQYATMDAVYLAKVHRHLLEIIDKCYPEPASENLTALGEKYQKIESQWKPLDSEIAEIKERIKTGMLAKKLKDSAYFELSSSITMKVDFMTLANLTQAEKIDLNLPVTLTKEIQRQLGELIDHPSLQIEENQSLRLIFNTQQRRKSTNKIVPLPVSEDLIILGERYKEILPEWKFLDSEVDHLKERVKKAMVVQNKANTPHFKLSSSSMMKVDFASLARLVQSVGIELDFMVTLTQYIQKRLGEAINQIDVQVEYITSWRMKAKTVEDEDEEIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F665</accession>
    <name>A0A2G4F665_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acireductone dioxygenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase</fullName>
            <shortName evidence="8">DHK-MTPene dioxygenase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Acireductone dioxygenase (Fe(2+)-requiring)</fullName>
            <shortName evidence="8">ARD'</shortName>
            <shortName evidence="8">Fe-ARD</shortName>
            <ecNumber evidence="8">1.13.11.54</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Acireductone dioxygenase (Ni(2+)-requiring)</fullName>
            <shortName evidence="8">ARD</shortName>
            <shortName evidence="8">Ni-ARD</shortName>
            <ecNumber evidence="8">1.13.11.53</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mtnD</name>
        <name evidence="9" type="ORF">CP500_000980</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:49016"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.53"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16723"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="8">Binds 1 Fe(2+) cation per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="8">Binds 1 nickel ion per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acireductone dioxygenase (ARD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.54" evidence="8"/>
    <dbReference type="EC" id="1.13.11.53" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57246">
        <property type="protein sequence ID" value="PHX57246"/>
        <property type="gene ID" value="CP500_000980"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00878"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010308">
        <property type="term" value="F:acireductone dioxygenase (Ni2+-requiring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010309">
        <property type="term" value="F:acireductone dioxygenase [iron(II)-requiring] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02232">
        <property type="entry name" value="cupin_ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01682">
        <property type="entry name" value="Salvage_MtnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004313">
        <property type="entry name" value="ARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023956">
        <property type="entry name" value="ARD_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418">
        <property type="entry name" value="PTHR23418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03079">
        <property type="entry name" value="ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 8 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="1 8" id="KW-0533">Nickel</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="site" description="May play a role in transmitting local conformational changes" evidence="8">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="site" description="Important to generate the dianion" evidence="8">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="20697" checksum="84B8C7147047CE1A" modified="2018-01-31" version="1">MAILRLENGTTYTQLSDITRELAPLNIQLNSWPVGDNPEIQELLAKDAIDDNQKEQVLQALDGYFQQLKESAGYQSRDLIVLHPDIPNLDTLLSKFDKCHIHADDEVRYIVAGEGIFGFVRPDGSQVEVTVQPEEFINVPANTEHWFYLTGTRKIKAVRYFTTTTGWTPEYTNTQIRSGLAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F691</accession>
    <name>A0A2G4F691_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Pyruvate dehydrogenase E1 component subunit beta</fullName>
            <ecNumber evidence="3 6">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_001455</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="3 6"/>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57211">
        <property type="protein sequence ID" value="PHX57211"/>
        <property type="gene ID" value="CP500_001455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027110">
        <property type="entry name" value="PDHB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624">
        <property type="entry name" value="PTHR11624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="7">
        <location>
            <begin position="4"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="327" mass="35991" checksum="AE764162741DD86D" modified="2018-01-31" version="1">MAETLLFNALREALDEEMARDSAVFVLGEDVGQYGGSYKVTKDLYNKYGELRVLDTPIAENSFTGMAVGAAMTGLRPIIEGMNMGFLLLAFNQISNNAGMLRYTSGGNFKMPMVIRGPGGVGRQLGAEHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKSAIRDDNPVLFFEHVLLYNLKEDLPETEYLVPLDKAEIVRSGKDVTILTYSRMRHHVMQGVPALVKEGYDPEVIDLISLKPLDMETIGESIRKTHKVIIVEECMKTGGIGAELIASISDRYFDELDAPVLRLSSQDIPTPYNGNLEKLTIVQTPQIIEAVQKMVNGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F699</accession>
    <name>A0A2G4F699_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57313">
        <property type="protein sequence ID" value="PHX57313"/>
        <property type="gene ID" value="CP500_000590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12679" checksum="5596783AED336892" modified="2018-01-31" version="1">MKLLFDENLSPKLPNRLSDIFPNSLHVRDVGMKATFDPIVWDYAKDNNLMIVSKDADMHDLSLVFGNPPKVIWLRLGNCSTLQIENLLRREFNAIELFYEDENLSLLALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6C9</accession>
    <name>A0A2G4F6C9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppnK</name>
        <name evidence="5" type="synonym">nadK</name>
        <name evidence="6" type="ORF">CP500_000560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57308">
        <property type="protein sequence ID" value="PHX57308"/>
        <property type="gene ID" value="CP500_000560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="78"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="152"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="193"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="305" mass="33076" checksum="798BE68F17B58339" modified="2018-01-31" version="1">MPKAGIIYNDVKPVSCRIAEELKQQLTAIGWDVCAVSGSGGILGYSSPDRPMCHTPIDQLVPPGFDSDMEFAVVLGGDGTVLSAFRQVAPIGVPLLTVNTGHMGFLTETYLNLLPQALEKVLAGEYEIEERSMLAVRLFRDNDCLWEALCLNEMVLHREPLTCMCHFEIAIGQHASVDIAADGIIISTPTGSTAYALSAGGPVIIPGVPVLQLVPLCPHSMASRALVFSNTEPVKILPASPNRLVMVVDGNGGCYVRPEDWVQVEKAPYRARFVRVQPPEFFHVLREKLGWGLPHIAKPSSVELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6E8</accession>
    <name>A0A2G4F6E8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57319">
        <property type="protein sequence ID" value="PHX57319"/>
        <property type="gene ID" value="CP500_000625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="22743" checksum="1622FFE9D8A66474" modified="2018-01-31" version="1">MIAAREQERYFTPEEYFAWEEQQLERHELIDGRVYAMSGGTQNHSAIAINFLLSIKTHLRGNQCRVFNSDLKVNILNTRNYTYPDLSVTCDRRDNSSPQYITYPCLIVEVLSDSTEAYDRGKKFEKYRRNPNLVDYVLVSSDEMAIDMYHKNEAGDWLILSYRAGDRVELKSIGLSLAIEQFYEEIIFERSPDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6L6</accession>
    <name>A0A2G4F6L6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3086 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57434">
        <property type="protein sequence ID" value="PHX57434"/>
        <property type="gene ID" value="CP500_000420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021437">
        <property type="entry name" value="DUF3086"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11285">
        <property type="entry name" value="DUF3086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="446" mass="49797" checksum="E6EEE52B959C9985" modified="2018-01-31" version="1">MNSDESPTQEPQVQPIAPTVEGELNLPVNQAFDQLPSEAPDLPRVEEPESITQMPSETDIQLNESNSEITEIVYPAGALAQILPNIEFHPSQEESAIAQIHPQPDSTPTPATKMVTDIEENVTENLAERVQVLQQQAEDLTEKIATLEAEKVKALEALGEAQTSIGRLVQDGLIQLEQRKQTLQIEVEKLERRRDRIQKEMRTTFAGVSQDLAIRVQGFKDYLVGSLQDLAATAELLDLTPPVPEKTQQFAVAESSSSAPINPRFSEQGFQEQAKQIRRTLDQYRTLPDYYGPAWQLRRTFEPIHAERVSNWFFTQGGRGALRTMGSRLQNILITSTIVSVLTSVYGSRVRTLVLANSPERLGEWRRGLQDCLGITRSDFGPERGIIMFESAEALAQKADRLVKDGKLPLIVIDETEDLISLSMLQFPLWLAFASDPQSLIAAKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUH3</accession>
    <name>A0A2G4EUH3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000250">
        <property type="protein sequence ID" value="PHX53181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53181">
        <property type="protein sequence ID" value="PHX53181"/>
        <property type="gene ID" value="CP500_022870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8318" checksum="26E943789B34B36A" modified="2018-01-31" version="1">MPIAPSKTMTGREGWWSRSRNRLFIGGKKNVGAYIYNFIYCAILSTFTADSTFMKYSLSQLGEVQGNGANRASAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUT5</accession>
    <name>A0A2G4EUT5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="8">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">folD</name>
        <name evidence="11" type="ORF">CP500_022620</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="8"/>
    <dbReference type="EC" id="3.5.4.9" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000236">
        <property type="protein sequence ID" value="PHX53226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53226">
        <property type="protein sequence ID" value="PHX53226"/>
        <property type="gene ID" value="CP500_022620"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="1 8" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="9">
        <location>
            <begin position="9"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="10">
        <location>
            <begin position="127"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="169"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="296" mass="31444" checksum="DD304D0158703F5E" modified="2018-01-31" version="1">MDAKIAQILDGKALATKIQGELGDRVRSMQTQIGRLPGLAVLMVGDNPASAAYVRNKERACAKVGIASFGKHYPANATQAELELAIHALNEDDRVDGILVQLPLPDHLDAISLLYQIAPDKDADGLHPINLGRLVRGEPGLRSCTPAGVMRLLQEYRIDLKGKNAVVLGRSILVGKPMALMLLEADCTVTVAHSRSQNLESITSQADILIAAVGRTEMITANMVKPGAVVIDVGINRVVNLDGTSRLAGDVDFDAVKTLADFITPVPGGIGPMTVAMLLENTVSSYIKTAEKIGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV06</accession>
    <name>A0A2G4EV06_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rod shape-determining protein MreD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mreD</name>
        <name evidence="9" type="ORF">CP500_022150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MreD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000217">
        <property type="protein sequence ID" value="PHX53318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53318">
        <property type="protein sequence ID" value="PHX53318"/>
        <property type="gene ID" value="CP500_022150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007227">
        <property type="entry name" value="Cell_shape_determining_MreD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03426">
        <property type="entry name" value="shape_MreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="182" mass="20302" checksum="A11AB811BB16A229" modified="2018-01-31" version="1">MSARSRQFLNFSITFTSALLCLLILPTRMPGMELLGIGPNWVLMWVVAWSIKRKRTILGAAIMGLILGFLQDAMTAPHPSHAVSLVIVAVLTVVLLKTWSIPADIVERDPIPIALIVFGMAMLAETVMGIQFFAMGDRALMEVSVYHQRVALSSAILSSLWVPVLYFPLNRLWEMTKTLEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV77</accession>
    <name>A0A2G4EV77_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyl CoA synthetase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_021460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000196">
        <property type="protein sequence ID" value="PHX53452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53452">
        <property type="protein sequence ID" value="PHX53452"/>
        <property type="gene ID" value="CP500_021460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043758">
        <property type="term" value="F:acetate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043938">
        <property type="entry name" value="Ligase_CoA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032875">
        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19045">
        <property type="entry name" value="Ligase_CoA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13607">
        <property type="entry name" value="Succ_CoA_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="517"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="755"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="913" mass="99455" checksum="4BD4D5845450C59C" modified="2018-01-31" version="1">MEKISKNQTSLCDPAHDIWKEQRHPLDGIFHPRSVAVIGASEREGSVGRTILWNLIRSPFGGTVFPVNPQRPSVLGIKSYPDIASVPEVVDLAVIATPAATVPQVIRECVAVGVKGAIIVSAGFKEIGEAGIALEQQVIAEARRGGMRIIGPNCLGLMNPIAGLNATFASTIARAGNVAFISQSGALCTSILDWSLGENVGFSAFVSIGSMLDVGWGDLIEYLGDDPHTHSIVLYMESIGDARAFLSAAREVAMDKPIIVLKVGQTEAAAKAAASHTGALTGSDAVLNAAFRRCGVLRVHTISDLFDMAEILAKQPRPKGNRLSIVTNAGGPGAIATDALISGGGALSELAPETLQQLNQFLPPQWSHHNPIDILGDASSDRYAQTLEVVASDPNSDGLLVILTPQAMTNPTLTAEKLKAYSKLGKPILSSWMGGAEIAAGTQILNQAHIPTFPYPDTAVRLFNYMWQYTYNLRGIYETPSLPADSEIHAPDRILAAQILTKVSKSDRTLLTEYESKQLLAAYGIPTIDTSIATSDMEAVEIADRLGYPVVLKLHSETITHKTDVGGVHLNLADAAAVSRAFAEIESKLSAIDPAAFLGVTVQPMVKMEGYELILGSSLDPQFGAVILFGMGGQLVEIFQDRALALPPLNTTLARRMMEQTRIYKALQGVRGRQAIDLIKLEQLLVSFSQLIVEQPQIQEIDINPLLVSPDGMVALDARVLLHTTADFAQRPVPAIRPYPTQHVQEWESRKGDRLTIRPIRPEDEPLMVKFHQNLSEESVYLRYAHTVKLKQRIAHERLTRICFIDYDREMLLVADRQDPQTLEHEILAVGRLSKLHGTNEAEFALIVGDRYQNQGLGTEILRRLLEVGKDEQLSAIVGYILTSNYQMQSLCRKLGFEFQPDRETGMLKAIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV86</accession>
    <name>A0A2G4EV86_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000206">
        <property type="protein sequence ID" value="PHX53376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53376">
        <property type="protein sequence ID" value="PHX53376"/>
        <property type="gene ID" value="CP500_021810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="8453" checksum="E177744DC6E59531" modified="2018-01-31" version="1">MATSFGRIFRRIEKILTYLNLIDLIKFDRDRDHRLNVILFGLCSIRNCDKIFFVLTRTANNCDRTTRAQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVB4</accession>
    <name>A0A2G4EVB4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000192">
        <property type="protein sequence ID" value="PHX53474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53474">
        <property type="protein sequence ID" value="PHX53474"/>
        <property type="gene ID" value="CP500_021285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="49" mass="5565" checksum="978FC428BA3477CA" modified="2018-01-31" version="1">MNLSKSLRNAMRYISEAAIRLFSPTDDNYPSTGVQPFEGKSSKNNDKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVS3</accession>
    <name>A0A2G4EVS3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000169">
        <property type="protein sequence ID" value="PHX53633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53633">
        <property type="protein sequence ID" value="PHX53633"/>
        <property type="gene ID" value="CP500_020430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042217">
        <property type="entry name" value="T4SS_VirB10/TrbI"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013592577" evidence="1">
        <location>
            <begin position="31"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="217" mass="22707" checksum="1CA3E4ABF0C25E6B" modified="2018-01-31" version="1">MITSQKLRSTAAAILALGITLGTSAPLVVATPAAAQRFSQLDSVRIPSGSVIPVSYEKDKIVMTPDETAPLTLRVAQDIRTAQGRVLIPAGSEIVGQLEPVTRRNRKGTQFVARELIINRRQRYQIDGISGIITRTERVQKGASGGSVAQGAALGAAAAAALGGITGDRAIATEEVLGGAGIGALAGVFLGRRNVEVIVIRPQEDLAIRLRSDIVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVY7</accession>
    <name>A0A2G4EVY7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="8">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tyrS</name>
        <name evidence="10" type="ORF">CP500_020025</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53695">
        <property type="protein sequence ID" value="PHX53695"/>
        <property type="gene ID" value="CP500_020025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02007">
        <property type="entry name" value="Tyr_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024108">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF1">
        <property type="entry name" value="PTHR11766:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="243"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="410" mass="44986" checksum="ACC780AA8B93E818" modified="2018-01-31" version="1">MVFDRTPMISPNLSGIYRGVSEIFPDRPDSSNPDENLVKLLTKGDRPLRIKLGIDPTGTDIHLGHSICVRKLRAFQDAGHTAVLLIGDFTARIGDPTGKSETRAQLTAAQVAENAKTYLDQVRPILDFDTPGRLEIRYNSEWLSGLDLAKILDLLGTMSVQQMLAKEGFDNRMEQGTAIYLHEFLYPLMQGYDSVALEADVELGGTDQKFNIAVGRDLQRHFGMKPQFGLLMPILIGTDGVQKMSKSLNNYVGLSDDPLTMYSKLEKIADRSIAQYFELLTDLPLDALPENPREKQKLLAVNVVSQYWGKEAGDRAQLDAMALVKGAAGEADAVAEFSLASVQFPAKLFYILSASGLCKSSGDARKLMQGGGVKLEGDKVSDVNLTFESPAELEGKVLQVGKNKFVRLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW28</accession>
    <name>A0A2G4EW28_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53735">
        <property type="protein sequence ID" value="PHX53735"/>
        <property type="gene ID" value="CP500_019940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="123" mass="14740" checksum="57B1705F15D725BC" modified="2018-01-31" version="1">MLDIIFYAFKTNQPPHYVRMSEDVYEWLAKSEFSKIGKSVPRNILIDEEEEKLPLVELDQDIRQKFRNFFRDAIICESDTVLAKLGDSPLKEEYQAETYRLRKLLDLLKCVENENYQYLQRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWI4</accession>
    <name>A0A2G4EWI4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5 6">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadE</name>
        <name evidence="10" type="ORF">CP500_019370</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="5 6"/>
    <dbReference type="EMBL" id="NXIB02000150">
        <property type="protein sequence ID" value="PHX53838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53838">
        <property type="protein sequence ID" value="PHX53838"/>
        <property type="gene ID" value="CP500_019370"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="469"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="469"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for glutaminase activity" evidence="5">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" description="For glutaminase activity" evidence="5">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutaminase activity" evidence="5">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="314"/>
            <end position="321"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="570"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="599" mass="64357" checksum="84BF26CA324E22F3" modified="2018-01-31" version="1">MKIAIAQLNPTIGDIFGNSNLILEAAKKAAGEGANLLLTPELSLIGYPPRDLLMNPSFIAAAGAQLQQLAQNLPADLVVIVGTAIPNAHSGKKGGKSLFNSAAVLSNGIVKQIFHKRLLPTYDVFDEDRYFEPGENSNYFNLGELKIGVTICEDLWNNEDFWGKRSYVGEPFLDLVKVGVDLVVNLSASPYSMGKRGVRSAMLQHSVIRSGIPIVYANQVGGNDDLIFDGSSFSVNKKGELIQVLASFETDFAVIEYDEAKQDLIGISSQNQTEITPAQLSFTPQVGDAEIWAALVLGVRDYVRKCGFSKVVLGLSGGIDSALVATIASFAIGPKNVLGVLMPSPYSSDHSVNDALELAKNLGIGMEMLPIADLMKTYDRTLADLFINTTFGIAEENIQSRIRGNLLMAISNKFGHLLLSTGNKSEMAVGYCTLYGDMNGGLAVISDVPKTRVYSLCRWLNSVGAVPPCPPSPPCPPSSPSPPCPPSSPSPPCPPQGNEIIPGNIISKAPSAELKPGQIDQDSLPAYDVLDDILQRLIENHESVKQIVVAGHDEAVVARIVKLVRQAEFKRRQAPPGLKISDRAFGTGWRMPIAKSSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX20</accession>
    <name>A0A2G4EX20_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adenylate/guanylate cyclase domain-containing response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_018055</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54071">
        <property type="protein sequence ID" value="PHX54071"/>
        <property type="gene ID" value="CP500_018055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="12"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="5">
        <location>
            <begin position="203"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="379" mass="42045" checksum="1273C5606A6A246B" modified="2018-01-31" version="1">MDSNQYPTSQASILVVDDKPDNVRLLSTILTEKGYQVRKALNGQRAIATVQEFPPHLILLDVMMPEMNGYEVCAKLKASPKTSAIPVIFLSALDDVSDKVKAFDVGAVDYITKPFQEKEVLARVANQLTIQNQQRLLQEQTKQLEEIVGRLQNEIKERQGVELALRLAQKKSDHLLLNILPAAIVENLKKGERTAAERFDSATVLFADIVDFTSLAARISPLELVNFLNQIFSTFDQLTEKHGLEKIKTNGDAYMVAGGLPVARADHVEAIANMALDMQAAIAHFQTDTGEPFQIRIGIHTGPVVAGVIGTKKFSYDLWGDTVNVASRMESQGLPGYIQVTTAIYEELKDRYVFEERGAIEVKGKGEMIAYWLKAKKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX76</accession>
    <name>A0A2G4EX76_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Segregation/condensation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54076">
        <property type="protein sequence ID" value="PHX54076"/>
        <property type="gene ID" value="CP500_018105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="270" mass="30672" checksum="C0CD5DB43D76F87F" modified="2018-01-31" version="1">MTVAKGQDGLETISEGIALLIDLAERGEINPWDVKVIEVFDRCLSKLNEARDREQSGDFSDLSHSGQAFLYASMLVLLKAESIVLSEPPQNDSAEEEGLENLENSGGRQLPQHLERQLRRRGVAQLPQKRAVTLPELIEQLQLMKAAMEQTVAPRRRQTSKMRSQAAQAIFELAHQENLVETASELERFLGERNSEIDEGWLDLEQLLELWPHHDFHSPVDSELPVLSSEVHSPNYDRVGIFWALLLLSAQSKVELVQEEFYRDLKIRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX87</accession>
    <name>A0A2G4EX87_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54154">
        <property type="protein sequence ID" value="PHX54154"/>
        <property type="gene ID" value="CP500_017665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013592578" evidence="2">
        <location>
            <begin position="31"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="293" mass="29433" checksum="126F70908D498AB3" modified="2018-01-31" version="1">MKNLNCWNHPAVLLSAIAIVVGSLSANTIAAVAQSTSNLSQDTENVSLKNSPTFKIAQAGSLCRKVTPKEGLTIRQGPETKSARVGGVAMNTQVTLAAGATAIKGSDGRLWMEITAPVKGYVAIGYPNNDRNLVSCTTGSAVTPSPSPAPAPAPAPKPAPAPTPAPAPAPAPTPAPAPAPMPAPAPAPAPMPSPAPAPVPAPSPAPTPAPAPAPGPVSLCRQVEPRVAPNGLVIRADASKTAAIKGSVAANGKVTLVPNFKSVKDKKEENRNWVEVSSPVAGFVSAGNLIMCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXA6</accession>
    <name>A0A2G4EXA6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridoxal phosphate-dependent aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000118">
        <property type="protein sequence ID" value="PHX54175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54175">
        <property type="protein sequence ID" value="PHX54175"/>
        <property type="gene ID" value="CP500_017540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="36"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="393" mass="43471" checksum="377C617DAAFAF977" modified="2018-01-31" version="1">MTLDWITTADRLQTLPPYVFARLDELKARAREQGLDLIDLGMGNPDGATPQPVVEAAIAAIQNPANHGYPPFEGTTSFRRTITKWYSRRYNVELDPESEALPLLGSKEGLAHFAMTYINPGDVILVPSPAYPVLFRGPIIAGAKVHNIILKPENDWVIDLADIPDRVAEQAKILYFNYPSNPTGATAPREFFKDVVAFAHKHQILLVHDLCYAELAFDGYQPTSLLEIPGGKEIGVEFHTMSKTYNMAGWRVGFVVGNSKIIQGLRTLKTNLDYGIFSALQTAAEAALQLPDSYLKEVQNRYSTRRDFMVAGLAELGWNIPKPLAAMYLWVPCTRGMSSTDFALNVLQQTGVVVTPGNAFGPGGEGYVRISLIADCDRLGEALRRLKQANIRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXE3</accession>
    <name>A0A2G4EXE3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017625</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54146">
        <property type="protein sequence ID" value="PHX54146"/>
        <property type="gene ID" value="CP500_017625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="12"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="149"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="216" mass="24345" checksum="7FF0A8C44E136321" modified="2018-01-31" version="1">MTKDNNSGDQKRLMLVDDDPNLILLVKDYLEFRGYNVITAENGRHALEKLEEEVPNLIICDVMMPEMDGYTLVKHIREDPRTSWIPVLFLSAKGQSSDRVKGLSTGADVYIVKPFEPEELVAQVESSLKAASRLIRHRNESLDGSLKAKARRNVELTPTELKVVQLLAQGLANRQIAEVMKVSQRTIESHVSNMLGKTALHNRTELARWALESKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXG9</accession>
    <name>A0A2G4EXG9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_017480</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000117">
        <property type="protein sequence ID" value="PHX54178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54178">
        <property type="protein sequence ID" value="PHX54178"/>
        <property type="gene ID" value="CP500_017480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010802">
        <property type="entry name" value="DUF1400"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005065">
        <property type="entry name" value="PAF_acetylhydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PTHR10272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07176">
        <property type="entry name" value="DUF1400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013706939" evidence="4">
        <location>
            <begin position="34"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1400" evidence="5">
        <location>
            <begin position="33"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="551" mass="58714" checksum="0B66B98032FD5CD0" modified="2018-01-31" version="1">MSIKTTFKWLSSVASMSIAIAISTLSGTAPVQAAETLVVRKGILESSISVADLRSLVETGKVPDGLQSYANLLSSEQRSQIFGALKAKIPLNVVGLSSLLNTRVGTAILADLTTVIPRRDGAGVEALRAALVLGANKPEGLSVLSFIENYPGRRVVVDLDRAFAVLANLNTGFWQTQRFMAAIAPQLGANKTALNLPFDASQAGPNAVQILKLDLNDTARDRRIPVDVYWSKAATADKPTIVFSHGLGSVRTDLRYLAEHLASHGYIVAALEHPGSNEANTNAAIVGQSRLIAPQEFLNRPKDISFVLDELAKLNKTDVNLQGKIAIDKSMVIGYSFGGGAALSLAGAEMQLGRLKQRCQADLITLSLGEGIQCAAAGLPEERYQLRDQRIKRAIAMNPTTSLLFGETGLSKIQIPTLIVAGSADKTTPALVEQIIGFPQIPSPKWLVGFVGATHLSVKDPSTTLDQVGKPSTVITGDEVVGDKAISIRNYIKAISLAMAAQLTTDADKYAVFLTPDYAQFASTPALPVRLVTEIPPEANAIVETFIKENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXH6</accession>
    <name>A0A2G4EXH6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_019255</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000148">
        <property type="protein sequence ID" value="PHX53857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53857">
        <property type="protein sequence ID" value="PHX53857"/>
        <property type="gene ID" value="CP500_019255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024320">
        <property type="entry name" value="LPG_synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031553">
        <property type="entry name" value="tRNA-synt_2_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09924">
        <property type="entry name" value="LPG_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16995">
        <property type="entry name" value="tRNA-synt_2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_2_TM" evidence="9">
        <location>
            <begin position="17"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="LPG_synthase_C" evidence="8">
        <location>
            <begin position="237"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="559" mass="62770" checksum="E457B82BCDD74377" modified="2018-01-31" version="1">MLTEKTRIGLWTASFLTGLVGVINLLSAVTPSLPDRRNWLEPFFPFTVRAGGHFFAAVIGFMLLTLATNLLRRKRIAWLVTVALLMLSIVVHLVKGLDVEESLLSGVLLFHLLVMRKSFTAKSDRPSIAQGIRVLVGALLFTLAYGTMGFYILDGRFEVNERAVNFDWDRALFQTLAMFFTADDAGLVPKTRFAMFFADSIYGVDSVTLGYALLMLLRPVLLRNSASFSERNEAQEIVGKYGRTTIARLALLEDKSYYFSPSGKSTIAYVPKGRGAIALGDPIGPPEDRKEAIVGFQEFCDRNDWYPTFYQTLPDDLEIYYALGFRVVQIGEAAIVNLKDFTLKGKANQNLRTAINRLTKAEHQVKFYEPPLSSELMRQMKAVSDEWLQMVQGAEKKFSVGWFNETYLRETPVIAIHTPDGKISAFANMISPGDRVIGVDLMRRRTEVENGTMECLFASMLQHCQALGYAEFDLGLSALAGVGEAEKSGRLEKVLIYLSEHLNKFYNFQGLHSFKDKFGPRWEPRYLVYPSLGSLPDVVVALIRADSGDRIWDYLRPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXL7</accession>
    <name>A0A2G4EXL7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3038 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54190">
        <property type="protein sequence ID" value="PHX54190"/>
        <property type="gene ID" value="CP500_017415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021399">
        <property type="entry name" value="DUF3038"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11237">
        <property type="entry name" value="DUF3038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="22608" checksum="404D0B485A9F6C61" modified="2018-01-31" version="1">MRSIVKSSAPTNETGTSPNWEELTQKAPEPTQLDNIKSQLDLVLLALEALTGIGSEAMLKVAVELNLESMVADRVALWRLRQSNPLRKGQGGRKKLDVEEARSLVLISCHLAKQHQALIRRAVALLEQMAEQNREPHTVALLGDYIDRFSNTYGDRMEDAENLSGAQLTNLALKLLIDLLFYSSPGGHRRLWLALLDRAKSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXQ3</accession>
    <name>A0A2G4EXQ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54322">
        <property type="protein sequence ID" value="PHX54322"/>
        <property type="gene ID" value="CP500_016745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="8774" checksum="6D663986C7AC1DAA" modified="2018-01-31" version="1">MSPTSEMDDDLRPEYDFTQLSVVARGQGRKQSTLTVQLDPDVATIFPDSGAVNEGLRLLMRLIQHSPSQPSAQSVTASKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXR5</accession>
    <name>A0A2G4EXR5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_016995</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2Fe2S plant-type ferredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54268">
        <property type="protein sequence ID" value="PHX54268"/>
        <property type="gene ID" value="CP500_016995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010241">
        <property type="entry name" value="Fd_pln"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02008">
        <property type="entry name" value="fdx_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="6">
        <location>
            <begin position="4"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="10769" checksum="C9AE88E86BD084A4" modified="2018-01-31" version="1">MATYKVTLISEAEGLNQTIEVEEDTYILDAAEEAGLDLPYSCRAGACSTCAGKILKGTVDQSDQSFLDDDQIEAGYVLTCVAYPTSDCTIETHKEEDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXZ4</accession>
    <name>A0A2G4EXZ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000104">
        <property type="protein sequence ID" value="PHX54391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54391">
        <property type="protein sequence ID" value="PHX54391"/>
        <property type="gene ID" value="CP500_016405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8312" checksum="89F33A7D0C69B281" modified="2018-01-31" version="1">MTSQLKQAIDIAQSLSLTEQLELLKTLSAIIQRTHSLEIQATTTEEDTDFSAVSFRQSWQQAMTEQTLPLETDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXZ6</accession>
    <name>A0A2G4EXZ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2555 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54356">
        <property type="protein sequence ID" value="PHX54356"/>
        <property type="gene ID" value="CP500_016510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019678">
        <property type="entry name" value="DUF2555"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10742">
        <property type="entry name" value="DUF2555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8098" checksum="42144452111AE56B" modified="2018-01-31" version="1">MKTLTKASRDIAVLTSEDVAELAVRLEVDDYTDPFEGLNDWHLLRSLAFQRPEMVEPYLHLLDMEAYDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY34</accession>
    <name>A0A2G4EY34_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_016055</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54444">
        <property type="protein sequence ID" value="PHX54444"/>
        <property type="gene ID" value="CP500_016055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FHA" evidence="4">
        <location>
            <begin position="25"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="151"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="413" mass="45339" checksum="9D7964FFD517FE81" modified="2018-01-31" version="1">MLLTLLDPEQNTPLQQWSFESESIVRIGRSPENHIVIPNALVSRQHLELQRIKSGVSSQWYLVNSGTNGTFVNGMPLSQGWISDGALIQLARGGPLLHFQVTTIELGGKIGTMPPMTRPSPVCTHAGNPPGSLFCIRCGEPMTVDRTVRNYQVLRTLGQGGMGTTTLAWDREKAKAQKPGSSPADSLVVLKEMNADMAQIAKAQELFEREAKTLKSLNHPGIPKFFDFFVEGGKKYLVMEMLHGEDLEKRIYNRGPVPPQQAIEWMIQTCEVLGYIHSQNPPLVHRDIKPANLLVRHRDNGISVIDFGAVKEIGTPPGTRIGVEGYTAPEQDRGQPLPQSDLYAIGPTLIFLLTASSPQKYYGKIAGGYGFKLENIPTVGPKLRDIILKTTAAKPGDRFQTAKQLAQSLSACL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY36</accession>
    <name>A0A2G4EY36_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="5">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aspartate transcarbamylase</fullName>
            <shortName evidence="5">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrB</name>
        <name evidence="9" type="ORF">CP500_016045</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54442">
        <property type="protein sequence ID" value="PHX54442"/>
        <property type="gene ID" value="CP500_016045"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="168"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="326" mass="35687" checksum="A52DD180331E7987" modified="2018-01-31" version="1">MTWTRRHILTLADFTSDEYDTVLQTAASFREVLGRRTKKVPALQGQVVANLFFEPSTRTRNSFELAAKRLSADTLNFTPGSSSLTKGETILDTAKTYLAMGTDLMVIRHGQAGVPSTIASEMDRLGSRVSVLNAGDGQHEHPSQGLLDLFTICSLLDAESPRLKLLAGKKIAVVGDILHSRVARSNIWSLTASGAEVHLAGPPTLLPLLFAECGNGREGKLFLHWQLEPALQDADFVMTLRLQKERMSQNLLPSLREYHALYGITRDRLKLCKPDVKVLHPGPVNRGVEISSDLMDDAQFSLISQQVTSGVAVRMALLYLIGGGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY46</accession>
    <name>A0A2G4EY46_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54452">
        <property type="protein sequence ID" value="PHX54452"/>
        <property type="gene ID" value="CP500_016100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="59" mass="6715" checksum="43D6624A7D6E9BC8" modified="2018-01-31" version="1">MLQEKCLKPWTIVRSLPNLDKVVVGQFRSWSDADGHLQLLKRMVPADRLTVVFDPVVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY49</accession>
    <name>A0A2G4EY49_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxylate-amine ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54465">
        <property type="protein sequence ID" value="PHX54465"/>
        <property type="gene ID" value="CP500_015875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038752">
        <property type="entry name" value="IQCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041356">
        <property type="entry name" value="PGM1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14465">
        <property type="entry name" value="PTHR14465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18105">
        <property type="entry name" value="PGM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM1_C" evidence="1">
        <location>
            <begin position="444"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="506" mass="57353" checksum="823E9C92F1398F28" modified="2018-01-31" version="1">MQKLKNAESEYGQQFRNLQIELRERWQKIEEFDSGDCDIIVIPSISLDQQEMQKVPGAYHYEERHLFSLIRLRNPRTRLIYITSEPLHPMIIDYYLQLLPGIPFSHARDRLLLFSTYDASAKSLTQKILERPRLMERIRQAVRSTKCYMVCYNSTSLERELSVKLGIPLWASDPDLLYWGTKSGSRQIFAESGVPYPDGSELVWNVADLAEAAAQLWERQPHLQRIVIKLNEGFSGEGNAILELKPIANTAHSEKVKLISDCFLHLRFQATGETWENFSSRIPELGAIAEAFIEGSEKRSPSVQGRIVPSGEVEILSTHDQILGGPDGQIFLGCRFPADESYRLALQESGRKIGHNLAEKGALEQFGIDYVAVRQEDGKWDIQAIEINLRKGGTTHPFMALKLLTNGRYEGSTGSFYSQQGRPKYYVASDNLKKERYRGLLPNDLMDIIADNQLHFDSGTETGTVFHLMGCLSEFGKLGLTSIGNSQQEAEDIYNKVVKVLDRETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY60</accession>
    <name>A0A2G4EY60_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54459">
        <property type="protein sequence ID" value="PHX54459"/>
        <property type="gene ID" value="CP500_016005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="224" mass="25493" checksum="2ADA0D1951B1E214" modified="2018-01-31" version="1">MTRIICLANSWKRGERCIAGINELQGKWVRPISDLPDGQIPKEMRQINRLEPALLDVLDIPLAKTGPDFGFESENLSILPGKWRQVGKVPPAYLLKYCNSQAYILHNDLRYVTVEYMQSLPKGDRLTLQLVKAVKITVKKLIQRFEGGNKWEGSIVTNHNQRLTATITDPVFIRKLELGYLPQKACLVTVSLSMPWRPDDWEGDDPCWKLIAGVIELPEDLVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYB7</accession>
    <name>A0A2G4EYB7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_015710</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54511">
        <property type="protein sequence ID" value="PHX54511"/>
        <property type="gene ID" value="CP500_015710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="549"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="42"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="584" mass="62650" checksum="394250CA3258D76D" modified="2018-01-31" version="1">MPHPHSKSVHCINPDCPKPYPQTWGNNFCQSCGAPLRLKNRYVPLQVLGKGGFAAIYTVWDTESQTERVLKVLLETSPKALKLFEQEAWVLALLRHPGVPRVEAEGYFHVQMQNLPGEGNAAARRLPCLVMEKIHGKTLEAVLDEHPQGCPQEWVLSWLSQAVEILEELHRCQIIHRDIKPSNLMLRVPQSPQLLLANGLGGLQLVTIDFGGVKQMGGVAPMGNDSPSSTRLISPGYSPPEQIVGGGVGPATDFYALGRTCIHLLTGKYPAEIEDPMTGELRWRHISPIAPAFANLLDDMVRSDVQHRPATAGDVRQRLRQISSRNKGQIAIAPIGQAILKFCREVLVAGAQKTVSLTGFVFGAIAQIVVASLDTGWEMVLGGIGGSAGAIGGLVLGYASPIGPEIANFLNEGLHQLIPNMTFAVGPEVLLFGFAGLGTAIGLTDAGSFRQQKQYWLSGLMGVQGYLLAGLCWLESSASSGVEGIILGGFAIATLTIGMGLRSHQLVHALVVAVCSTGVFLFLNALSIFPGSFLESFASSNATLGLWEVWGAVAFFGLLGSAIGLCLGVSHYLVVPLLRWLGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYG2</accession>
    <name>A0A2G4EYG2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54551">
        <property type="protein sequence ID" value="PHX54551"/>
        <property type="gene ID" value="CP500_015470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="PTHR19353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="2">
        <location>
            <begin position="77"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="379" mass="43108" checksum="6E9AB238F21A5FB5" modified="2018-01-31" version="1">MKSEKTLNTLDKTATPTLGEETLIHHSVYVKKLRPLLPPEAFEPDPNKLAILLINLVIVLLGWGIASHLDQWPVYLLWLYLPLAVIMGNSIIVLLFSSHDLMHGSVQKKSWLTYPIAFLGLSMLFMPPTQWKNLHTLVHHNNTNSLADPDRNYLYQQPDTWGKWIQNLFVPSVEVNPLWLIVGMAGSWFVHNFRNVSSVLLFNDKSVDYVPAAFTVSPKDRLTIALECAGILGIHLSILFYLEFHPIKIALAYILPIAIGHAGAMFYIYTNHMGCRMTAINDPLINSMSLRVPKIVDLLHLNFSYHTEHHIFPSINSNYYPMVQELLKIHYPGRMNLIDAGEAWRLLMETPRHYKDEVTFTDSLGKMSVDCGKSQADQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYG6</accession>
    <name>A0A2G4EYG6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkene reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54500">
        <property type="protein sequence ID" value="PHX54500"/>
        <property type="gene ID" value="CP500_015800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="PTHR22893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="10"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="372" mass="40976" checksum="532D864D1823C782" modified="2018-01-31" version="1">MSIQTTSPALLSPFKLGDLPLKNRVVLAPLTRSRAGETRMPNPLMAEYYAQRASAGLIITEATVISTQAIGWQNTPGIYSDEQLEAWKQIVTAVQTRETPIFMQLWHCGRASHSSFHENGQLPVAASAVKINGEGLHTPVGKQPYETPRALETDEIAIVVEDYRKAAERAKDAGFDGVEIHAANGYLIDTFLQTKTNHRTDAYGGGVENRYRFLKEIVEAIITVFPANRVGVRLSPNGVYNDMGSPDYRESFLYIAGQLNTYNLAYLHLLDGLAFGFHELGTPMMLGEFREVFAGTLIGNCGYTQELAETAISSGVADLIAFGRDLISNPDLVERFTHGWPLNPPAEMGAWYSFGPEGYVDFPTYQESQSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYM1</accession>
    <name>A0A2G4EYM1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="11 14">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ruvC</name>
        <name evidence="15" type="ORF">CP500_015200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 14">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the RuvC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="11 14"/>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54622">
        <property type="protein sequence ID" value="PHX54622"/>
        <property type="gene ID" value="CP500_015200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX54622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="19155" checksum="48FDE58068D6C6AC" modified="2018-01-31" version="1">MKKIILGLDPGLASLGYGAISCHIVPGKLDQNSVSMIDCGVIKTTPKQEMGERLKTIYEDLHAVIEQIKPDLAIAEKLFFYKMGNTILIAQARGVLTLVLAQCGVPLFEFTPAQIKKALTGRGNADKSEVQEAVARELELGYIPKPDDAADALAVALTGWYDDDICPKTIALETVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYN9</accession>
    <name>A0A2G4EYN9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54641">
        <property type="protein sequence ID" value="PHX54641"/>
        <property type="gene ID" value="CP500_015070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="18"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="218" mass="24800" checksum="B3188FCDD691EEF0" modified="2018-01-31" version="1">MSQIQTKILTDTWVTVTWDEYIEIIKQPEYEQAKCYYYNGQLRIEMAAVGPNHADDNGIIIILTNLFGIAKGIKMRLLVNCSYRKTGVREAQPDASYYIGERVQSTPRGSSIVNLDSAVAPDLAIEIADSSLLDDLGTKRMLYEELGVSEYWVVDVQKAQIIAFKIIANRGSERLTESEVLPGLKFALLEEGLRRSRETDHTEVGNWFLDEVRQEKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYQ5</accession>
    <name>A0A2G4EYQ5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2-carboxy-1,4-naphthoquinone phytyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.130</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">1,4-dihydroxy-2-naphthoate phytyltransferase</fullName>
            <shortName evidence="5">DHNA phytyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">menA</name>
        <name evidence="6" type="ORF">CP500_014940</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4-naphthoquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>1,4-dioxo-2-naphthoate + H(+) + phytyl diphosphate = CO2 + demethylphylloquinone + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:31087"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:75434"/>
            <dbReference type="ChEBI" id="CHEBI:87842"/>
            <dbReference type="EC" id="2.5.1.130"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; phylloquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MenA family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.130" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54652">
        <property type="protein sequence ID" value="PHX54652"/>
        <property type="gene ID" value="CP500_014940"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00995"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042372">
        <property type="term" value="P:phylloquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13962">
        <property type="entry name" value="PT_UbiA_UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01938">
        <property type="entry name" value="MenA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011937">
        <property type="entry name" value="DHNA_phytyltransferase_MenA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026046">
        <property type="entry name" value="UBIAD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13929">
        <property type="entry name" value="PTHR13929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005355">
        <property type="entry name" value="UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02235">
        <property type="entry name" value="menA_cyano-plnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="303" mass="33119" checksum="DA575E61270159E9" modified="2018-01-31" version="1">MTTKLIERSNSKLWLAAIKPPMYTVAVIPISVGTAIAFAETKTINSSIFSTFLISAILIIAWLNLTNDVFDSETGIDKNKAHSLVNLTGNKALIFWLANLFLALGVSGICAISWWQQDPTVILLVVLCCALGYTYQGPPFRLGYQGLGEFICFFTFGPLALAAAYYSQTQTWSATNFAASIIVGITTSIILFCSHFHQIADDLAAGKKSPIVRLGTKKGAELLQWLCGSVYALTVLFVALRMFPIWTLLIFGSVFFAIDLCRHVTNYHDQPTQVSNSKFIAVTLHFSSGLLLALGFALLALSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYU6</accession>
    <name>A0A2G4EYU6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphomethylpyrimidine synthase</fullName>
            <ecNumber evidence="10">4.1.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Hydroxymethylpyrimidine phosphate synthase</fullName>
            <shortName evidence="10">HMP-P synthase</shortName>
            <shortName evidence="10">HMP-phosphate synthase</shortName>
            <shortName evidence="10">HMPP synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thiamine biosynthesis protein ThiC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">thiC</name>
        <name evidence="11" type="ORF">CP500_014645</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-deoxyadenosine + CO + formate + 3 H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:24840"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.99.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ThiC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.17" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54695">
        <property type="protein sequence ID" value="PHX54695"/>
        <property type="gene ID" value="CP500_014645"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00089">
        <property type="entry name" value="ThiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037509">
        <property type="entry name" value="ThiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="195"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="236"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="457" mass="50811" checksum="75A6D87E49928507" modified="2018-01-31" version="1">MRTEWIAKRSGQSNVSQMHYARQGVITEEMHYVAKRENLLPELIRAEVARGRMIIPANINHTNLEPMAIGIASKCKVNANIGASPNSSNMQEEVDKLVLAIKYGADTVMDLSTGGGNLDEIRTTIIKASTVPIGTVPIYQALESVHGNMESLTANDFLHIIEKHAQQGVDYQTIHAGILIEHLPLVRDRLTGIVSRGGGILARWMLHHHKQNPLYTHFNDIIEIFKKYDVSFSLGDSLRPGCTHDASDAAQLAELKTLGQLTRKAWEHDVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARGRPGARDRDDELSKARYNFDWNRQFELSLDPERAKEYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAKEPVAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYX9</accession>
    <name>A0A2G4EYX9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <shortName evidence="7">LS</shortName>
            <shortName evidence="7">Lumazine synthase</shortName>
            <ecNumber evidence="4 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ribH</name>
        <name evidence="8" type="ORF">CP500_014540</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="4 7"/>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54724">
        <property type="protein sequence ID" value="PHX54724"/>
        <property type="gene ID" value="CP500_014540"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="PTHR21058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="SSF52121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="61"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="85"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="1-deoxy-L-glycero-tetrulose 4-phosphate binding" evidence="7">
        <location>
            <begin position="90"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>(2S)-2-hydroxy-3-oxobutyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="182" mass="19652" checksum="BBC554C08D2CF68D" modified="2018-01-31" version="1">MAVFEGNFTQTESLRFAIVIGRFNDMVVNKLLDGCQDCLKRHGVDINPHGNQVDFYWVPGCFEIPLIARQAAFSRRYDVVICLGAVIRGQTPHFDFVAGEVSKGIAAAAFQSGVPVIFGVVTTDTMQQALERAGIKSNLGWNYAMSALEMGTLMRQVNGLGGSSYDQLAAASAVEVLSGDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYZ8</accession>
    <name>A0A2G4EYZ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54753">
        <property type="protein sequence ID" value="PHX54753"/>
        <property type="gene ID" value="CP500_014305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="427" mass="46047" checksum="88359ADA07FC4078" modified="2018-01-31" version="1">MKRKSWQLFTIFGLVGLLLSAVVSCGKPAVNSPTQNSAVIEFWTMQLQPQFTEYFNQTIANFEKENPAVNVRWVDVPWSAMESKILGAVSAKTAPDVVNLNPDFASLLAGRNAWLDLDSRISEKVRSTYLPNIWKAGVLDGKTFGIPWYLTTGVTIYNTDLFKKAGITKPPATYAELAQVAKQVKEKTGKFAFFVTFVPEDSGEVLQSLVQMGVTLVDAQGKAAFNTDKGKAAFGYWVDLYKGGFLPKDVLVQGHRRAIELYQSGDTALLASGPQFLKAIAENAPSIGAVSAVAPQITGESGKKTVAVMNLVVPRDSKRPDDAVKFALFVTNSQNQLAFAKAANVLPSTVEALGDGYFKSVAADATAGDRARIVSASGLTSAELLIPPLKDVKKLQKAIYDNLQAAMLGEKSVEQAVADAAVAWDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ00</accession>
    <name>A0A2G4EZ00_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54417">
        <property type="protein sequence ID" value="PHX54417"/>
        <property type="gene ID" value="CP500_016160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="40" mass="4370" checksum="E3C37B3102ED6D38" modified="2018-01-31" version="1">MDVKLVLAVLTAVFTVCCLFFGTKNGFYDSDKYHGNGSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ54</accession>
    <name>A0A2G4EZ54_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54789">
        <property type="protein sequence ID" value="PHX54789"/>
        <property type="gene ID" value="CP500_014065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="397" mass="44520" checksum="3AA98A2B5D785577" modified="2018-01-31" version="1">MTQQQPRICILGGGFGGLYTALRLSQLPFSKAEKPEIVLVDKRDRFLFVPLLYELITGELQTWEIAPPFVELLENTGVRFCQGTVSGIDVETKRVQLHDGPEFECDRLVLALGGETPLDMVKGAVEYAYSFRSLDDAYRLEERLRFLEAKETDKIRIAIVGAGYSGVELACKLADRLGDKGRVRLIEQGDTILRTSPEFNRESATKVLEKRQVWIDLETAVEAIGSDTISLLYKGQLDVLPVDIVLWTVGTQVSQAVRSLPLKQNQRGQLITNPTLQIIDHPDIFALGDLAECHDETGQKLPTTAQTAFQQADYTAWNIWASLCDRPLLPFRYQPLGEMMTLGIDNATLSGLGIQLDGQLAHIARRLAYLYRMPTFDHQVKVGFNWISKPIQELLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ81</accession>
    <name>A0A2G4EZ81_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase</fullName>
            <shortName evidence="6">UDP-N-acetylglucosamine acyltransferase</shortName>
            <ecNumber evidence="6">2.3.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lpxA</name>
        <name evidence="8" type="ORF">CP500_013905</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a (3R)-hydroxyacyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine = a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:67812"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="2.3.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transferase hexapeptide repeat family. LpxA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.129" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54819">
        <property type="protein sequence ID" value="PHX54819"/>
        <property type="gene ID" value="CP500_013905"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008780">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03351">
        <property type="entry name" value="LbH_UDP-GlcNAc_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00387">
        <property type="entry name" value="LpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029098">
        <property type="entry name" value="Acetyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037157">
        <property type="entry name" value="Acetyltransf_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010137">
        <property type="entry name" value="Lipid_A_LpxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43480">
        <property type="entry name" value="PTHR43480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13720">
        <property type="entry name" value="Acetyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000456">
        <property type="entry name" value="UDP-GlcNAc_acltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01852">
        <property type="entry name" value="lipid_A_lpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_11" evidence="7">
        <location>
            <begin position="176"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="264" mass="28885" checksum="99C4BD31CA98B4EB" modified="2018-01-31" version="1">MLTLIHPTAVIHPRAELHSTVEVGAYAVIGERVKIGPETKIGAHAIIDGLTEIGARNQIFPGAAIGLEPQDLKYQGSLTRVDIGDDNLIREYVTINRATQPGESTTIGNHNLLMAYVHVGHNCAIADRVIIANAVALAGHVKIESQARLSGVLGVHQFVHIGRLSMVGGLSRIDRDVPPYMLIEGNPSRVRSINKIGLQRAGLTAEDLELLKKTFRILYRSGYTLNQALEQLDLLPKNPHLQHLRTFVQESVTKPRRGLIPGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZA1</accession>
    <name>A0A2G4EZA1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">UvrABC system protein A</fullName>
            <shortName evidence="13">UvrA protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrA</name>
        <name evidence="17" type="ORF">CP500_014040</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Forms a heterotetramer with UvrB during the search for lesions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ABC transporter superfamily. UvrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54843">
        <property type="protein sequence ID" value="PHX54843"/>
        <property type="gene ID" value="CP500_014040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00205">
        <property type="entry name" value="UvrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0742">SOS response</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="16">
        <location>
            <begin position="629"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="775"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="59"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <begin position="670"/>
            <end position="677"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX54843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="987" mass="108993" checksum="85B469984344DAD3" modified="2018-01-31" version="1">MSQRAETSNSQPSASRNGHNMTTSNSNNQNTIRVRGARQHNLKNIDLELPRDRLIVFTGVSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQLDKPDVDAIEGLSPAISIDQKSTSHNPRSTVGTVTEIYDYLRLLYGRAGEPHCPICDRSIAPQTIDEMCDRVMALPDGTRFHLLAPVVRGKKGTHRKLLSSLAAEGFSRVKVNGEILELSENIELDKNHTHNIEIVVDRLIKKPGLEERLVDSLGTCLRHSEGIAVIEELPTDENSEPNPPIVFSENFACPEHGAVMEELSPRLFSFNSPYGACPNCHGLGSLRTFAPDLVVPDVKAPIYCAIAPWSDKDNSYYLSLLCSVADNCGFNIDTPWHRLRPEHQQIILYGNEEKRTAENKKLDTSFTDLRRDFKGVISMLQRQYEDTGSDLIKQKLEQYRVDRSCEVCHGKRLKPEALSVRLGQYGIVDLTSISIRECRERVDNLGLSDRQFQISDLALREIKARLQFLLDVGLDYLTLDRATMTLSGGEAQRIRLATQIGSGLTGVLYVLDEPSIGLHQRDNFRLLQTLTKLRDLGNTLIVVEHDEETMRSADHIVDIGPGAGVHGGRIISQGSLEDLLAAEESLTGAYLSGKRVIETPNERRKGNGKSLSIKNARRNNLRNINVEIPLGKLVCVTGVSGSGKSTLINELLYPSLQHYLTKKVPLPPDMDALKTKGERSIEDVVDKVIVIDQSPIGRTPRSNPATYTGVFDVIRDLFAESIEAKARGYKAGQFSFNVKGGRCEACGGQGVNVISMNFLPDVYVQCEVCKGARYNRETLQVKYKGKSISDVLNMTVEEALEMFKNIPRAAMRLQTLLDVGLGYIQLGQPAPTLSGGEAQRVKLATELSRRATGKTLYLIDEPTTGLSFYDVHHLLNVLQRLVDKGNSILVIEHNLDVIRCCDWAIDLGPEGGDKGGEIIVAGTPEDVAANSRSYTGKYLQAVLQQHPLGEAVAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZB0</accession>
    <name>A0A2G4EZB0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <shortName evidence="8">BPG-independent PGAM</shortName>
            <shortName evidence="8">Phosphoglyceromutase</shortName>
            <shortName evidence="8">iPGM</shortName>
            <ecNumber evidence="8">5.4.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gpmI</name>
        <name evidence="14" type="ORF">CP500_013790</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54849">
        <property type="protein sequence ID" value="PHX54849"/>
        <property type="gene ID" value="CP500_013790"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046537">
        <property type="term" value="F:2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16010">
        <property type="entry name" value="iPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01038">
        <property type="entry name" value="GpmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011258">
        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="PTHR31637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001492">
        <property type="entry name" value="IPGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="SSF64158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="12">
        <location>
            <begin position="8"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="iPGM_N" evidence="13">
        <location>
            <begin position="85"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="156"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="258"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="8 9">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX54849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="533" mass="57771" checksum="95B0893FDA8D7130" modified="2018-01-31" version="1">MAQAFVSPVVLIILDGWGYREETDGNAIAAAKTPVMDSLWAVYPKTLIRTSGRAVGLPDGQMGNSEVGHLNIGAGRVVPQELVRISDAVEDGSLLSNPALVRLCEKVRASGGKLHLTGLCSEGGVHSHLSHIQGLLQLAKAQGIAEVCIHAITDGRDTTPKEGVEALAKIEGYIEKVAIGKIVTLSGRYYAMDRDKRWDRVQRAYDVMTTESVPDGRSAVEVLQASYDSGVTDEFAIPTRIAPGAVASGDGMIFFNFRPDRARELTQAFVDRNFKGFERQLIDPLIFASFTQYDPKLSSVLVAFEPQNLNNILGEVISKHGLRQLRSAETEKYAHVTYFFNGGLEAPFEGEDREMVQSPMVATYDEAPEMSAALVTDGALAAIEKGIYSFVAINYANPDMVGHTGMMDATIIAIETVDKCLGRLVTGVTKAGGTAIIIADHGNAEQMFDEDGNPWTAHTTNPVPFILVEGEGLKIPGHGTDVPLRDDGCLADIAPTILEFLRLPQPPEMTGRSMMRSADFEVRTNRSPVRVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZC5</accession>
    <name>A0A2G4EZC5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54537">
        <property type="protein sequence ID" value="PHX54537"/>
        <property type="gene ID" value="CP500_015565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="133" mass="15144" checksum="03B6B4A09FCD0AF5" modified="2018-01-31" version="1">MVKRKSLFPCGHKGYGKACHRCTQEFLAHLHCVQLLAEKQTKKQEKEASFARDIIDLRGLPDHIVTKARAIITALGENKNYRDFGGKRLRHNRLIVSIPLGRNYRMLCKDGGTFLIPQKVLSHEDYNVCKPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZK4</accession>
    <name>A0A2G4EZK4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Prevent-host-death family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54617">
        <property type="protein sequence ID" value="PHX54617"/>
        <property type="gene ID" value="CP500_015170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8272" checksum="D2016A220B630D38" modified="2018-01-31" version="1">MAQITTTELPQTLQTLLIEVERTKTPLTVIHEGKALVIIYPATTQTLRPSFGAMKGSGEILGDLIAPVAEPWEVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZN2</accession>
    <name>A0A2G4EZN2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pirin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014965</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54657">
        <property type="protein sequence ID" value="PHX54657"/>
        <property type="gene ID" value="CP500_014965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041602">
        <property type="entry name" value="Quercetinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="PTHR43212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17954">
        <property type="entry name" value="Pirin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="8"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C_2" evidence="4">
        <location>
            <begin position="146"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="232" mass="25538" checksum="1E3EDC2603258B7E" modified="2018-01-31" version="1">MIAIRKSAARGHANHGWLDSYHTFSFANYYDPNYMSFRSLRVINEDIINPGKGFGTHGHQDMEIITYVLQGALEHKDSLGTGAVIKPGEVQRMSAGTGIQHSEFNHSQTDPVHLLQIWLLPDTNGLSPSYEQRDFPVAERHGNLRLVAARDARDGAVKINQDVDLYAAILDKNSQVSHVLDSNRHGWVQVARGSVLLNGLALEKGDGAAVSDESELVIEATEDAEILLFDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZQ0</accession>
    <name>A0A2G4EZQ0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmk</name>
        <name evidence="11" type="ORF">CP500_013265</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54986">
        <property type="protein sequence ID" value="PHX54986"/>
        <property type="gene ID" value="CP500_013265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="4"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="11"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="185" mass="20924" checksum="BFDE9E96DA45FA1E" modified="2018-01-31" version="1">MKSGKLIVLTGPSGVGKGTLVRSLLTRHPELHLSVSVTTRSPREGEIEGQHYYFVDRSRFEQMLEAEELAEWAEFAGNLYGTPYFALQQGIEEGEFILLEIELEGARQIRNKFPEAVRIFILPPSWEELERRLRSRGLDSESAIARRLLRAKAEIEAAGEFDFQVINDDLEVALTGLESVLFVNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZR0</accession>
    <name>A0A2G4EZR0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54996">
        <property type="protein sequence ID" value="PHX54996"/>
        <property type="gene ID" value="CP500_013315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="525" mass="59141" checksum="B771DB743C3070B9" modified="2018-01-31" version="1">MSLTEQILSQLPGDALGSLRKVDRLWENLKQNTAPVPEAVKHSQQPLETIDFDIVISGATLGILIGTALAVRGWRVALLERGTLRGRDQEWNISRQELEAFVELNLLSVAEIEKAVATEYNPARISFPDTPDIWVRDVLNIGVDPVYLLETLKQRFLQAGGKLFENTPFNTATIHPNGIVIESKNTNLESESESESNSFQTRLLLDAMGHFSPIVRQARQGKKPDAVCLVVGSCAQGFPKNDTGDIFASFTPMQNQCQYFWEAFPARDGRTTYLFTYLDADTERFSLETLFEDYLRLLPQYQNVELNQLKFQRALYGFFPCYRQSPLKTPWNRILPVGDSSGSQSPLSFGGFGAMVRHLKRLTLGIDEALRSDSLNQNAIALLQPYQPNLSVTWLFQRSMSAAMNQKIEPNQINQLLSGVFEVMEEFGEPVLKPFLQDIVLFPALSKTLLKTAISHPGLVMKIIPQVGVANLLDWMVHYVNLGIYTGLQPFGKALEPQIKKLSLEQQYYFHRLIEAWEYGAGGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZY7</accession>
    <name>A0A2G4EZY7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase</fullName>
            <ecNumber evidence="7">6.3.2.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Meso-A2pm-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Meso-diaminopimelate-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-tripeptide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murE</name>
        <name evidence="13" type="ORF">CP500_012645</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:23676"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.13" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55065">
        <property type="protein sequence ID" value="PHX55065"/>
        <property type="gene ID" value="CP500_012645"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008765">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00208">
        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="10">
        <location>
            <begin position="25"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="12">
        <location>
            <begin position="184"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="11">
        <location>
            <begin position="406"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="228"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Meso-diaminopimelate binding" evidence="7">
        <location>
            <begin position="483"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Meso-diaminopimelate recognition motif" evidence="7">
        <location>
            <begin position="483"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="186"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="534"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="538"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="569" mass="60862" checksum="B562F0E4F084172C" modified="2018-01-31" version="1">MKLRELLAAVPSISFDAQHPALDAEVTGLSTNSHACKSGDLFLGMPGTRVDGGDFWQSAIANGAVAAVISTQAAEKTPPQPPLSKGGLEEQISPLSKGGLEEQISPLSKGGLEEQISPLSKGVLEEQISPLSKGGLEEQIPPLSKGGLGGVPCVIPAGDMAEVCGHIATAFYGNPASKLKLVGVTGTNGKTTTTHLIEFFLNQMQLPTAIFGTLYTRWPGYEKTALHTTPFAVELQKQLAESVAAGCKYAVMEVSSHALAQQRVLGCAFEVAVFTNLTQDHLDYHKDMEDYFAAKALLFSPNYLKNRAVVNIDDAYGRRIVQSLNSEQVWSYSTTDKTADLYADDLEYQPNGVKGILHTPNGKTAFTLPLVGQFNLSNMLAAVGAALELGLDLSAIVTKLSEFAGVPGRMERVQISADQDISVIVDYAHTPDSLENLLKASRPFIPGRMICVFGCGGDRDRTKRPIMGKIVAELADVAVVTSDNPRTEVPDRILDDVIAGIPAEVKPIVICDRADAIRTAIMDAKPGDGVLIAGKGHEDYQILGTEKVHFDDREQARNALNERINGVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F066</accession>
    <name>A0A2G4F066_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2'-5' RNA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55150">
        <property type="protein sequence ID" value="PHX55150"/>
        <property type="gene ID" value="CP500_012260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019039">
        <property type="entry name" value="RNA_ligase_T4-Rnl1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09511">
        <property type="entry name" value="RNA_lig_T4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA_lig_T4_1" evidence="2">
        <location>
            <begin position="51"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="361" mass="42383" checksum="893C395D9CA4610C" modified="2018-01-31" version="1">MELQEYLRQHGLENLSETYHIKVTRDRQYPDLVCLKYSQIESPLGEKIVQQCRGIILDSSQDWQIVSYPYDKFFNYGEIHAAKIDWNSAKVYEKLDGSLIVLYFFNQKWRVQSSGTPDAAGEVNGFGFSFAELFWKVWQELGYQLPQETDQCFIFELMTPYNRIVVQQKNNQIVFHGVRNTQTLIEMEPTTWANKYGWELVKSYALTSWKEVIEASQQLDPMDSEGYIICDAKFNRVKVKSPQYVAISHLREGFSTRRMIEIILTNEGEEFLAYFPEWTELYQKVKDKYQSLVQEIEDVYRQHESIEVQKDFAFAVKHLPYSGILFSLRARRVAGVKEALRDVTIHKIEELLGLDYIHLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0C3</accession>
    <name>A0A2G4F0C3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55209">
        <property type="protein sequence ID" value="PHX55209"/>
        <property type="gene ID" value="CP500_011965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="85" mass="9861" checksum="537842078A684D45" modified="2018-01-31" version="1">MLSPAPNLVEQINDWEFIELWVDPIVFPPRILMLVGDKNSKCCIYDPSANYKLLFLSSSYDQAHSWLLEDEYERVDGRLLASEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0D4</accession>
    <name>A0A2G4F0D4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ybeY</name>
        <name evidence="8" type="ORF">CP500_013545</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54907">
        <property type="protein sequence ID" value="PHX54907"/>
        <property type="gene ID" value="CP500_013545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46986">
        <property type="entry name" value="PTHR46986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="182" mass="20106" checksum="B988CD8A3390FE20" modified="2018-01-31" version="1">MQIEVNVEDCYGLAQQSADDSNQPQSAPSGEISAGTWETWFSVWLENQAADVPAAPGYEVSLRLTGDDEMQSLNSQYRHQDRSTDVLAFAALEVDCPQPDEMSSSEPLYLGDIVISIDTAHRQAQQQGHPLKTELAWLAAHGFLHLLGWDHPDEESLTQMLDRQEILLQGIGLALQTPSQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0E1</accession>
    <name>A0A2G4F0E1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54917">
        <property type="protein sequence ID" value="PHX54917"/>
        <property type="gene ID" value="CP500_013600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="356" mass="38755" checksum="EF1F3C01D2746550" modified="2018-01-31" version="1">MSSTSEKSSTSPSLLSAQTLVIVGIVWGVMALLFFLLFSVPLSQEEGLPLWYSIGTYIFECGAYLGAALVCFRNWNSPHMASGRNVWLGIGLGMLFYFVAGVLFGIWELYFEVSPDVSPADAFYLGSYVVLIGGMVVAVTSKRLNLEIWQWGLLSGIAAFGIVIALWVAAPDSWRVQLGLAPASTEEVVSKAAPDSTKVTAKAPALKDAPASKSKELTSPAAESGQPVAAEETEETKAPAWVIALDKQLLPYAYAINLFYIVGDVFLLIIATALLLAFWGGRFSQSWRMIAAATFSLYIADMYFKWRDTQAEGTYQSGSLLEVFFVFSAILFGIGAVLEHDISSRSRQSRRSRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0I5</accession>
    <name>A0A2G4F0I5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">G-D-S-L family lipolytic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54967">
        <property type="protein sequence ID" value="PHX54967"/>
        <property type="gene ID" value="CP500_013165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="24"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="230" mass="26362" checksum="2A4817E91049A8E8" modified="2018-01-31" version="1">MQVATAHSFSHLRPITSHPMKLVAFGDSLIYGFGDNVGGGWVERLRRQWMLSESPGHVLYNLGVRGDRAYQVSQRLENEFRHRGELRNRVPDAMIISVGLNDSARVQSAIGRNYTDFDHFKTVVDHLLNLSQQLCPVIFVGMVPVDESKMPFQDCLYYSHADQYRYKEATRVACLERGIPYLDIFDKWCDRGSDWWRSRLIADGLHPNVAGYQALFEDVTSWEPLASISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0K9</accession>
    <name>A0A2G4F0K9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_011655</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55304">
        <property type="protein sequence ID" value="PHX55304"/>
        <property type="gene ID" value="CP500_011655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="807"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="1067"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="1386"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="2">
        <location>
            <begin position="1559"/>
            <end position="1726"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="295"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="421"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1754" mass="199223" checksum="4226556C129B0F8A" modified="2018-01-31" version="1">MNINDSKSSVFIVTGMHRSGTSLTASLFQKVGVDIGKKLVGPADGNVKGHFENVDFVEFHKGVLRSHGIDELGCTFDKTIPLAPESVEIAKKLIAENQQTDKHWGWKDPRTALFWDFWLTLLPEANFICVYRSPWEVVDSLYRRGTDVSLLNNPEMAVKMWIHYNQQVLELHKRFPDRCLLSNVYPIGNHPELFIDRVNQKFNVNLTAIPADNFEESLLVNDIEKSHRPNLIQQYFPEALEIYQILETQAQDLNSQMSLSPDKIISFPASAVGHFQDWLNIRLLEKQQKTSKYEVKQWQEQFQQAQTKVLGLETELGQTQVQLAGKESQFQEALAKLLELETELGQTQVQLAGKESQFQEALAKLLELEAQLGETQIQLAGKKSNFRTALEKILDLESKLGKKQTEIEQKEFESKQESAKFLRLETEKKQIQENLRETIINLEKLCQEIEIVRAELAKIKSSTLWKIIDNILDIKRRLRELFPRFIFSIDGSNNLHIYDSDLVITGWAFHSQFSIKSVRAKIDRKFFTGICGIERSDVAQAHSNIAAAKKSGFRIELVAPPGRHEVLLEVQDAKSKWHLLAVYPLLVSTIQASFDTPIVWEQRPGQVLFAGWCCHHDRKIAKLILACGDVSVECAYGLRRKDVGEVFPDWVNSSESGFEALVNLPVGEWLVSLEAELETGEILSFQAPKTLTVKPYDIWRRSADKFEELSRLSEAIRQRARERQQRLGRILPMPWEIVAVVRQFAKIYRQQKQFTAPGELLPPAGFVVPQPIDRYDAWLDVNQWNERSRNYLISRLESCQEPLPKISVVMPVYNPQVEFLSSAIGSVFNQVYQNWELCIADDCSTDLTVIETLKNWATKDNRIQITFRKENGNISAATNSATELATGDIILFLDNDDELTPDALGEVALYFATHPTTDFLYSDDDKIDTKGRRFSPQFKPEWSPELLLSYMYLGHLCAVRKQIFEQIGGLRLGFEGSQDYDFALRATEISRHVAHLPLVLYHWRTAPGSTAISGAAKPASFAAGQQAIQDALNRQQIKGNVAQHEWATKENLGIFAQDFPDSGPSVTIIIPTKNQEKLLKSCLDSLEATTYKNYQILVIDNESDDPKSLEYLKQLNCQVLPIKNKEGKFSYAAINNRAVEQSESEYILFLNNDTEIINPRWLSQMVGYAQISGVGAVGARLLYPDNKIQHAGIIHGLHHGLAGHAFKLMNSDNRGYLSQAMVTRNYSAVTAACMLTPRELFLELGGFDEENFAVAYNDADYGYRLLENGYRCVYCPDAELLHKEGASRGFNDNPREVAAFRRKYADKKDAFYSPHLSLEDEYFHIQPVRFFMKEEGSSATDSVTDVTDGWKKEKLKFGDLGSFKSANGFVNPVKVLMCSNSLDFTGAPLHQYEIAVKLAKEGVIKPIAFCVSDGPLRQAYEQQGIEVIIYDNPLEHIYQRDAYDEAIYNFSKEIKKLKVDAIYANTLENFFVIDAAQQIGIPTVWNVHESAPWQTYFNRFGSEIAARALECFRFPYKVIFVADATRDRYLPLNSHHNFRVIHNGLDLSRLDNSDNSELARNSLGVEAEDVVILLLGTVCERKGQQDLVKALALLSDNFHNKIRCFIVGDRPSIYSTKLAELVGELPQKLRQRVTVVPETSETGKYYQAADIFVCTSRIESFPRVILEAMACDLPIITTPVFGIKEQVRPGINGLFYTPDRPEELAASLHSLLEDKVLRQRLAENAKYVLESLNTFEEMTEAYGQIFREAYFTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0L7</accession>
    <name>A0A2G4F0L7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4160 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55278">
        <property type="protein sequence ID" value="PHX55278"/>
        <property type="gene ID" value="CP500_011565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025427">
        <property type="entry name" value="DUF4160"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13711">
        <property type="entry name" value="DUF4160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9469" checksum="C0550A2798E3C8C9" modified="2018-01-31" version="1">MPTILRIGPYRLYFYSHEPNEPPHVHIDRDNSSVKFWLEPVSLGNNLGFSAKELRKIQSVVQENQQTLLEAWYGYFGDSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0R9</accession>
    <name>A0A2G4F0R9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpsR</name>
        <name evidence="4" type="synonym">rps18</name>
        <name evidence="6" type="ORF">CP500_011315</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006631377.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000056.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55346">
        <property type="protein sequence ID" value="PHX55346"/>
        <property type="gene ID" value="CP500_011315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018275">
        <property type="entry name" value="Ribosomal_S18_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00057">
        <property type="entry name" value="RIBOSOMAL_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="8316" checksum="0D41ECE4BD43A004" modified="2018-01-31" version="1">MTYFRRRVSPIKPGDPIDYKDVDLLKKYVTERGKILPRRITGLTAKQQRDLTRSIKRARIVALMPFVNQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0W1</accession>
    <name>A0A2G4F0W1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PhoD-like phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55378">
        <property type="protein sequence ID" value="PHX55378"/>
        <property type="gene ID" value="CP500_010910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="868" mass="98544" checksum="9BA0083953E79DA8" modified="2018-01-31" version="1">MTWTPLNHRIHHLPLILAGPILRRTESQAVTVWLALKAPRQVELKVYSTEGGTGEIVDRPLLQGTSSTVQLGKYLHVVAVTAKAIDRNFLTSGQIYAYDVEFAGRPEPSGVPGLEHERENLLSCLWPIAADSSLLGPQTISYFDHQLPTFALPPDDLNYLRIAHGSCRKPHGGGRDALPILDSSIEQFAGMANSRPHQLFLTGDQIYGDDVADPMLWALTDAGDGLLGWKENLPLMDAKIQDNLCTSIPKNPKKRNEFCEPRENSTESQFQEQAEAQYKYKQPVDLKPGTRSDIARDFGGFTAMLANKPDNAKSHLFGLGEYYAMYLLVWSPVLWCDRFPKGKDICENVKQAKVWDREAFELESFSRNLWRVRRAIANIPTYTICDDHDVSDDWYLNREWCYRVLGKPLGRRVVQNALLAYAVFQAWGNTPAQFNAGKVGNKLLRSATKWSESAGSDDLAWEKVSQYLGIPAVDIETGLPKFKLDEDVLILDRDDEVLNWHFTIRSFKHEVIVLDTRTWRGYPTESAIDPPMLLTHKGFEEQIQQPLKETELLNATGEFEIEATLVVVPTNLVGLWIIDAVQKWDVEHGKVFDSDAGDAWNFHELAFVKLLAEFFKRRARVVVLTGDIHYAAAVRLSYWSDCHFGDSPTEINRQDACSTNNRQDACSTGEGKEGVLGLNLAGYKSSCQYSVLAQLTASALINEEWKTHLIHTKIKSLLPERRHERLGWNEPLELVKISRINRKKSVAAAVKNRQSLPDWGYRIDWMKRQRARVFLQHTGEGLSSKSAKLSLVQRLWQIVSLLWRNRWLQEGDEIVGYSNIAIVSFQWPADRDGEKAVMQNVYWRPVWAPDSVVYSQYFVSLETGNEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Z7</accession>
    <name>A0A2G4F0Z7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55454">
        <property type="protein sequence ID" value="PHX55454"/>
        <property type="gene ID" value="CP500_010770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="16779" checksum="985C6DCA13FB3908" modified="2018-01-31" version="1">MSDQLKNRVAAPCIIDTGIVVNKRDIKRLLFDLGRVRYLHMQDGKIYSEGEGYVMEVFANPNRSTLIANRALYLNVDSFDYLELKKSNEEGAYFDLIQDGRQLRLIPLSNPAHEQVARNLNAAALDAVVDQVLSGSWDFQLDEDDSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F180</accession>
    <name>A0A2G4F180_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dynamin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55505">
        <property type="protein sequence ID" value="PHX55505"/>
        <property type="gene ID" value="CP500_010385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="198" mass="22249" checksum="2DE90028F50E89C7" modified="2018-01-31" version="1">MDTTTISTEVIDLLSRISRQKLREEDVTPLVVFLTALVSILRGVMIIDRTIALEEEERLQKTLKAFASSDRDRVGLIERIVSGISKQQVYFNPTELLTLTAFFSDSEKLLLICFGYEMSAVDGRIDLREQMYLTAIGQQLGIDSRYIAAIDATFTKEGTVDSEAFAEVKELLAPLKFESREPVFAASAKHLLSLLEHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1C3</accession>
    <name>A0A2G4F1C3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55574">
        <property type="protein sequence ID" value="PHX55574"/>
        <property type="gene ID" value="CP500_010110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="PTHR42957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF87" evidence="2">
        <location>
            <begin position="432"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="856"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="925" mass="105032" checksum="D8AB1EE3C5FB2F15" modified="2018-01-31" version="1">MLTNTSGVKYWRGSAPGTGQPQEIDTYNFHAVNVFKLKALSDFASGRFKLMEHLDPSGRVGFVAGWQKSLLKSLAYFSYTQFDDPSANASCGYSLRIVYHPAPQGSKSTEVYFLARVASNSSQKIAEDLQKKQAQHIKSSLRSPLYQFEENTENKFDSRPLWLDSNQQLSCYEIIKSEEIFQWLDPEDRQRQNFYYSPGSFQVNKANNMVALFEQLQGYKQPVCIDLTLVPTRVEGYEKKTTSRYLEALNQISKGIREEEIDPDSNTQRAKSVYEDIKKRYYSGIVFLYNFRVFSPDGDTCQSVANQLASTCTANTVSPRVVQVIDSQYAVQTALQVNINEQSCTPGMWDTSGRILRGFPGGPGMLKRLHRLVDLDEAAAFFRLPIPINQPCAGVEYETGSASVSETSKNTKRKTITIGNYYRNVKTNEVCEFDIEQLKTHLLVVGGSGSGKTTTTFNILTQLWEKHRIPFMVFDPKVTPEYRYLKRLPQFKDDLLIFTPGQELITPLRFNPFDVMPGIALQEHISRIFDCFMGALPLENPLPSFIQEAIDYHYDKKKWQLAHSRGGDVDKDGKSLETPTMQELYNKVLDLAQKNYGSDREVGDRMKGALKARLSRLVSKRGEGSMLQANRPLPFAELLSKPVIFELGGLNKEEQSLFSLFMLVFVFEYIRTVRIGQFQPQRTGERATDLDLRHVILVEEAHNILGKVQTSGDEGNSKSQVVDKFAQIMREMRAAGEGVIVVDQSPAALAQSIVDATNLKLMHRLPSPDDREYLGRAMCLTEGEAQLSGIFSPGEAFYYVPGWDAARRVATENFKNKPGVREQLETFFKDDDVIVSMDEFMERDREKLILGFQSAINRIDEKIAKFKNRLDRLKELLNKNQQKAGEKSASTKNIEDFDSQIKQNQELRQRFEYEIKILSSKTGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1U4</accession>
    <name>A0A2G4F1U4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55705">
        <property type="protein sequence ID" value="PHX55705"/>
        <property type="gene ID" value="CP500_009425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013545374" evidence="1">
        <location>
            <begin position="27"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="180" mass="20419" checksum="6C836387B8F414CD" modified="2018-01-31" version="1">MLSLNIKVLTTTFPLGVLSLFLSSYAASTNPSQPPYNLLNFNSIETNTSPIKPKQNLLVADINSEKISIKSIVLLQIKALNEENIEAYMSTIDPGYRGFEVTKNIQLQIFSQYDLKYVINQFDVISLSSNTAVIRVDQTTTKIRGPQFRNNRLVLIHNLNKSNGQWKMFSSEVQKIEYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1W1</accession>
    <name>A0A2G4F1W1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55736">
        <property type="protein sequence ID" value="PHX55736"/>
        <property type="gene ID" value="CP500_009255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="11745" checksum="05B049C00F181773" modified="2018-01-31" version="1">MNDNLPEILAELRHYFHKVYGERLVQLILYGSQARGDAKPDSDIDILVVLNGPVHAGKEIACTSEFIAALCLDRTVVISSAFASAARFQQEKSPFFLNVRKEGVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F215</accession>
    <name>A0A2G4F215_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR00266 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55801">
        <property type="protein sequence ID" value="PHX55801"/>
        <property type="gene ID" value="CP500_008930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00266">
        <property type="entry name" value="TIGR00266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="25469" checksum="5D8DB1B0AB1EB738" modified="2018-01-31" version="1">MADIIEYKIYGDDLQLIEIELDPQEGVRAEAGTMTYMEGGIEMQTTTGGLFQGFKRMFTGAGFFITTFVNNGNRKARVAFAAPYPGKVIPLDLSKLGGKFLCQKDSFLCAANGIEIEVAFTKRLGAGFFGGEGFILQKLQGDGLAFVHAGGTIVEKNLGVGEVLRVDTGCLVAFAPTVDYDIQFIGGFKNALFGGEGLFLAKMTGPGKVYIQSLPLSKLAERILAAAPSPMSSNSSSFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2B1</accession>
    <name>A0A2G4F2B1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system PemK/MazF family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55900">
        <property type="protein sequence ID" value="PHX55900"/>
        <property type="gene ID" value="CP500_008370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="12378" checksum="3D96ADEB05B1EEE8" modified="2018-01-31" version="1">MPYNRGDIVLVLFPNSDLRTAKRRPALIVQTNNLGTGLGQTIVAMITSNLARSGHPSRVFVALATPEGQQTGLLADSVIMTDNLVTLLEVEIDRKIGIWSDMVAVDAALKHTLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2C2</accession>
    <name>A0A2G4F2C2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chlororespiratory reduction protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55896">
        <property type="protein sequence ID" value="PHX55896"/>
        <property type="gene ID" value="CP500_008350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021954">
        <property type="entry name" value="CRR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038150">
        <property type="entry name" value="CRR7-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12095">
        <property type="entry name" value="CRR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9488" checksum="104B07784981AADE" modified="2018-01-31" version="1">MSLYDEDTFVVLETNQPEQFLTVVELLEKLKSVLASTPEDLPRDVQKFSAVEDQAKYLIDTYCELDVGPGKFLQWYAVRLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2E2</accession>
    <name>A0A2G4F2E2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55637">
        <property type="protein sequence ID" value="PHX55637"/>
        <property type="gene ID" value="CP500_009855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="164" mass="18463" checksum="8DA0C6959DA5D290" modified="2018-01-31" version="1">MDTHQVLEFVDKVVCAKTGKRLNDLQRGIIEGTLKQQKYSEIADTYRLTQGHVKDVGYELLQMLSNAFDEPVDKGNLKSVLARQDNLNISFGNSNIIGYINVCSDRPTAIPDQNQPKTPDFQQAKDEAKIETIGKLRQFGLSDEQIAEVLRLTLEEVQQVDKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2E3</accession>
    <name>A0A2G4F2E3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1565 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55931">
        <property type="protein sequence ID" value="PHX55931"/>
        <property type="gene ID" value="CP500_008125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011459">
        <property type="entry name" value="DUF1565"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022441">
        <property type="entry name" value="Para_beta_helix_rpt-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07602">
        <property type="entry name" value="DUF1565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03804">
        <property type="entry name" value="para_beta_helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1565" evidence="2">
        <location>
            <begin position="69"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="575" mass="60472" checksum="552E765D480B5EC9" modified="2018-01-31" version="1">MFINSKQNGCQENLSQSKALSSCLLVIFASVSFFKLQQSAIATETPIVQIIAQAQQSEINILYVSSSGGSDTAGNGSDRNPFKTITYALSVAPPNTAILLAPGTYSAQTGEQFPIVLQPNVTLQGNPNTRGQNIAIKGGGDFLSPTSAGQNITILAASGAKLSGVTVTNPNYRGYALWIESSSPTVVNNTFSGSTHDGISVVGNSRPMISGNFFSKNGANGMTIYGTSQPEVRDNVFENTGFGVNVAQQASPLLIGNQITGNKDGVVVQADATPVLRNNYIEKNRRDGIVAIARSLPDLGTMTEPGGNVIRNNGQHDVNNAAKGQIIQAYGNQLLSNRTTGQVQVAGTFSPSQSVGTPDLRLVSQPRRTGGPDSSLPVYTTPPSTPRTQRTPQRPLSAVSPSLVQNRSTSGQTPLSPLLAPRSVSPSAIAIPVPTPNSRSLAEISVEPSNVTPNFDSSSPVASEGKLPVPSRNIPLGRGGYVPAVLGGNSLPDSGENAPSVDRALALGFRYRVVVDTRSQGDRAKIQSLVPDAFRTFSNGREVIQVGAFREPEKADELLQILTANGLNARIEEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2E8</accession>
    <name>A0A2G4F2E8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thiamine-phosphate synthase</fullName>
            <shortName evidence="8">TP synthase</shortName>
            <shortName evidence="8">TPS</shortName>
            <ecNumber evidence="8">2.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Thiamine-phosphate pyrophosphorylase</fullName>
            <shortName evidence="8">TMP pyrophosphorylase</shortName>
            <shortName evidence="8">TMP-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">thiE</name>
        <name evidence="13" type="ORF">CP500_008120</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 8 9">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8 9">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 8 10">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55930">
        <property type="protein sequence ID" value="PHX55930"/>
        <property type="gene ID" value="CP500_008120"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01327">
        <property type="entry name" value="TMP_synthase_cyanobact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041397">
        <property type="entry name" value="ThiD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016229">
        <property type="entry name" value="TMP_synthase_cyanobac_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17792">
        <property type="entry name" value="ThiD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000512">
        <property type="entry name" value="TMP_PPase_Cyanobac_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiD2" evidence="12">
        <location>
            <begin position="17"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="TMP-TENI" evidence="11">
        <location>
            <begin position="151"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Unknown" evidence="8">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine-phosphate synthase" evidence="8">
        <location>
            <begin position="130"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="HMP-PP binding" evidence="8">
        <location>
            <begin position="177"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="THZ-P binding" evidence="8">
        <location>
            <begin position="274"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="360" mass="40325" checksum="B53EB27CA2709FE2" modified="2018-01-31" version="1">MTNKQNRILPAQPALCRILDANLDRAREGLRIIEEWCRFGLNSADLAGECKQLRQELAFWHTAELRSARDTPADPGTELTHPQEEQRSGLQQLLEANFCRVEEALRVLEEYGKVYDPNMGKAFKQMRYRVYTLESDLLGYQRYQQLLRSQLYLVTSGRDNLLGVVEAALQGGLTLVQYRDKTSDDAVKLANVRKLCELCHRYDALLIVNDRVDLAIAADADGVHLGQQDLPVAEARKLLGPGRTIGRSTTNAQEMQRAIEEGADYIGVGPVYSTPTKPDKQAAGLDYVRYAAAKSPIPWFAIGGIDINNLDQVLNAGASRVAVVRSIMEAEQPTLVTQFFISQLIRMQKLKTHKLITNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2M8</accession>
    <name>A0A2G4F2M8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56002">
        <property type="protein sequence ID" value="PHX56002"/>
        <property type="gene ID" value="CP500_007550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12844">
        <property type="entry name" value="HTH_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9117" checksum="995F2AFC760DC624" modified="2018-01-31" version="1">MGEANISGSRIKQAREKLGWGQSDLAAAIDVDFHIKLDQSDISEIERQKRGVKDFELDAIARLLQVTPEWLLRGDEANSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2N6</accession>
    <name>A0A2G4F2N6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56034">
        <property type="protein sequence ID" value="PHX56034"/>
        <property type="gene ID" value="CP500_007730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="470"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="799" mass="89728" checksum="119C97D4D3E807A2" modified="2018-01-31" version="1">MIPNVPRNAYTDSPEQDSNLILGSLQLLFWLFFHPSAWRNHLKRNPALWKLGIQAFLVVPVLANSIVVALVIWLLGAPVEKIASGVVLGVVSGVLLTSLGFSSREGKELNVALGIASGMLLGVVWGVASDLVWGVALDLLPGVQSVASDFFRDLLSDSRLKESLAIWDWRWWVPTWRWMLFFAVLAALGRFGATMRGASLGKDEIEAIDVVWGVMGVVWGVVWGVGLVVMVLCLPVVLYPFLTGWNILLYRLDILRTANKPSLLRWHSAFWDERQHLPLYGLDKHVLLVIERNPEEGEAAFNYLSTSRQRWAAPAVQIELDARGLERCKNVAAIGSKAHPNLALGELNSSVSFLLISFSRISEDVAAALNQKSSYNQRLALTVVAERLNGLIRELNRSGDKYAVRFRPIATQWHEIVTNYMQEQAKAVELRQEIDNPYIIGVPLTEQQEIFTGRADIGTRIEQLLLDRRRPPLLLYGQRRMGKTSLLNNLGRLLPSTIIPMFVDLQGPVSSASNYASFLYNIARSMANSAQRQSAFPLPSLDRETLQDDPFTRFDEWLDEVEQALQQNIALLALDEFEALDNAITKGRFDEEDVLGMLRHLIQHRPRFKVLLAGSHTIEGFQRWASYLINVQVVHISYLKQPEARQLIEQPVKDFTLRYELNAVERVLQLTRCHPFLIQLLCAEIIALKNEQNPSIRRLATLADVEAAIPEALSVGSFFFADIQSNQADAAGLAILQFLAARGEGAIVSRLTILQHFPDKSDALNLLLQRELIEEVSDGYRFEVELIRRWFASSPSVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2W2</accession>
    <name>A0A2G4F2W2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_007135</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56075">
        <property type="protein sequence ID" value="PHX56075"/>
        <property type="gene ID" value="CP500_007135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="165"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="292"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="396" mass="45097" checksum="5914AC6049ECA0B2" modified="2018-01-31" version="1">MLVFEFKAYGKSSQFTAVDEAIRTAQFVRNSCLRYWMDNQKMNKYDLNKYCAVLAGDFPFADELNSQARQASAERAWSAISRFHENCKKGIPGKKGYPQFQRDCRSVEYKSTGWKLANDRKSIKFTDKKGIGKLKLKGTRDLHFYSFTQIKRVRLVKRADGVYVQFCIDVNRSENIEPSGNTIGLDVGLKEYYTDSNGITVENPRFLRRCEKVLKRFQRRLYKKIKGSKNRGKARQILGKRHLKISRQRKDHAIKLARCVVQSNDLIAYEDLRIKNMVKNHCLAKSINDASWYQFRVWLEYFGKVFEKVTVAVNPQSTSQECSSCGAIVKKTLSTRTHVCQCGCVMDRDENAARNILSRGLGTVGHTGTLAVNASNALGELTSTQIGEILSEQVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Y7</accession>
    <name>A0A2G4F2Y7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4065 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56122">
        <property type="protein sequence ID" value="PHX56122"/>
        <property type="gene ID" value="CP500_006960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025272">
        <property type="entry name" value="SocA_Panacea"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13274">
        <property type="entry name" value="DUF4065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4065" evidence="1">
        <location>
            <begin position="33"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="158" mass="18940" checksum="309ADE1004082BA7" modified="2018-01-31" version="1">MTTITTITTASQLADYYIWFANDVGSYLSNHKLQKLLYYAQAWYLAFEDTPLFDEDFEAWVHGPTIPALFYEYKEKFDFKPILKEVKKPEFSEEVQEFLDELSDDYFFRDAYELELMVRREDPWINARGELPRDEPCHAIITKELMKKFYKSRVIEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F312</accession>
    <name>A0A2G4F312_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56151">
        <property type="protein sequence ID" value="PHX56151"/>
        <property type="gene ID" value="CP500_006820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013801053" evidence="1">
        <location>
            <begin position="24"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="12739" checksum="03EE5549AB2C6C73" modified="2018-01-31" version="1">MVNKLLSKLMIAAGLSLPLVALAASSVFAQMVKISVINNSGKTMTAVYMSPPDKNTWGQNELDGPIADREKADFEWNRADYGGSDGGCVFDVRAEYSDGKSTELDAVDLCQESAINFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F361</accession>
    <name>A0A2G4F361_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56186">
        <property type="protein sequence ID" value="PHX56186"/>
        <property type="gene ID" value="CP500_006670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="421" mass="43053" checksum="71D281EBDF426D9C" modified="2018-01-31" version="1">MSQNVTAKQMGLESAQDPIAVVATVETIPAETVAVESYADRLMDELFEGVDRAFQESGGLPTEPVKPEIITLKSISVPQIVLSSPPPMGGQRLEKDVVAIARRVALETTKKHQSKQSFDKMLLGAAFGSLLLVLGLWLASRSGWVRLPVAATTTGLTPTTKEKTAPDTEFSEYVQRSLDAIEQKKLPKGNAQLSGVPEVVPPGTLPNISISGAPPATAGLSTAVNRIADALEQAAVQPGSPALPAQVVIIPPATNPAEPPPTVAVSPSATAPASGRAVAVAGKASPSSSPVAASPSKSSEPKILARETEPATAPAAAPAATQPAATQPAAAPAATQPAAAQTQPTAPAVVSSAPTSAHTLVGVLELGDRSAALFEVDGVARRIYVGESIGSSGWTLGEIKNQEAVIRKGGDVRSVFVGQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F370</accession>
    <name>A0A2G4F370_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="10">2.4.1.227</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">murG</name>
        <name evidence="13" type="ORF">CP500_006775</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1-&gt;4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:31227"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="ChEBI" id="CHEBI:61388"/>
            <dbReference type="EC" id="2.4.1.227"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 28 family. MurG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.227" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56210">
        <property type="protein sequence ID" value="PHX56210"/>
        <property type="gene ID" value="CP500_006775"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01133">
        <property type="entry name" value="murG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="11">
        <location>
            <begin position="9"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="12">
        <location>
            <begin position="184"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetyl-alpha-D-glucosamine binding" evidence="10">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX56210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="361" mass="38878" checksum="459C6DACB630B430" modified="2018-01-31" version="1">MTKAPLRLLIAASGTGGHLFPAIATAQQLHDCHIEWLGVPDRMETQLVSSLYPLHTIAVEGFQQRFGLGTVRILAGLLGAILRVRRLLKRGNFQGVFTTGGYIAAPAILAARSLGLPVILHESNVFPGKVTRWFSPFCTKVAIGFEATAGYLPRAKTVVAGTPVRSQFLTHEPLNLPIPDSVPVILVMGGSQGAVAVNKLVRECAPAWFEAGAWVVHLTGNNDPDAESLKHTQYISMPFYDNVAGLLQRANLAISRSGASAMTELAVTGMPSILIPFPYAADNHQHFNAEVFAKAGAALLFPQNELTADLLKSKVLYLLSDAEYLAKMSKAAHQLAVTDSTERLANLVRQLLSKKSLVISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3K3</accession>
    <name>A0A2G4F3K3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56364">
        <property type="protein sequence ID" value="PHX56364"/>
        <property type="gene ID" value="CP500_005845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013733995" evidence="1">
        <location>
            <begin position="28"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="9515" checksum="F258C7FD71A46388" modified="2018-01-31" version="1">MLRFAIVALVTLELVLLTALGMNPANATVSNPEFYSWNFASVGSSELVCKKMVVAPQNLVLPSSPMQAVSISSAIVDEKFCAKSTKPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3W7</accession>
    <name>A0A2G4F3W7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56452">
        <property type="protein sequence ID" value="PHX56452"/>
        <property type="gene ID" value="CP500_005470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013854986" evidence="2">
        <location>
            <begin position="27"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="38"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="275" mass="30031" checksum="C0703BCDE5242FF4" modified="2018-01-31" version="1">MNKRLKLIFLTSSIICTVLFPSVSWARTVLQEIQQTGVLKVGIRKDAVFFGYESSGSWTGYCAGFANALASSLSKQMNTSISVRAVTSTLPTREGIVRDGTVHIECGPNTISREKEVQENIKYSEPFFVTGTQFIVRAANKNTSLKNARLGVLRGSTNIRSVTQAYSEAEIQQFSERSEGVSAAMNGQVTAFAGDSILLIGEAVRQGVPLSAFEIVPNQPLSCDFYGMILPTNDTQWQGTVNSFIGGSQGLQVWGTWFGGFRSYLKGTLDYCKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F414</accession>
    <name>A0A2G4F414_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphate transport system permease protein PstA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pstA</name>
        <name evidence="8" type="ORF">CP500_005195</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56486">
        <property type="protein sequence ID" value="PHX56486"/>
        <property type="gene ID" value="CP500_005195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005672">
        <property type="entry name" value="Phosphate_PstA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00974">
        <property type="entry name" value="3a0107s02c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="85"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="326" mass="34553" checksum="4E7DA6B932B0D135" modified="2018-01-31" version="1">MTQAKHTETILDAEIYNPLSLGRNFFSRGMNVISFAFTALALLPLFAILYKILGEGLTHLSWEVLVSLPAPVGVEDQPNGFANAILGTALMVGIATLFSVPIGIMTGIFLSEFGREHKAIADTIRFITVILSSVPSIVVGVFTYALIVVTTKVFSGLAGGIALGIIMLPVVALTTEQALKLVPTSYRLASGGLGAGRFQTIFKIIIPAALPTITTGILLAASRAAGETAPLIVTALSSQFWPPLIEKLGEITQSPIGAETISKLQEIPGTLLTPTPSMSVLIYSYASSPYKEQNELAWTAASVLLGMVLIASVASRAVTRKRLQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F481</accession>
    <name>A0A2G4F481_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_005060</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56521">
        <property type="protein sequence ID" value="PHX56521"/>
        <property type="gene ID" value="CP500_005060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="33"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="360"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="394"/>
            <end position="401"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="597" mass="67629" checksum="64ED8474B97596E6" modified="2018-01-31" version="1">MQRFNLTILKQFWSIAKSYWSSDEKWRARGLLLLVILLSFGYTGLSVLLNNKRGELISALSAQDEARFWQTILIFAGTLVIYAPLYAGYDYLRDRLGLEWRRWLTNYFIDRYFQNRAFYNLNHADADIDNPDQRIAEDVKSFTQESLKLLLVVVDSLLAVAAFSGVLWGISKPLILFLVLYALVGTLATVGVFGKPLMRLNFGQLKTEADFRFSLVRVRENAEAIAFYQGEDCESAQIKGRFVEAFDNFKRLIFWELNLNILTNAYEFIPFILPAIVVAPGIFAGELEVGKVTEAQGAFIRVFFSLNLIVARFQSLATFGAGVERLYTFLECLETHHLTSQESEEALETSIKTEIADDRLAIENMTLQTPNRQRTLVEDLSVKLSTGEGLLVRGPSGCGKSSLLRAIVGLWDAGTGKILRPTLDRMLFLSQRPYMILGTLRDQMLYPNMDGSVEDSQLRQILIQVNLPNLEQNYGGFNTEQNWAQVLSLGEQQRLIFARLLLNKPSYAILDEATSALDTHNEQLLYQQLQASGMTFLSIGHRESLSNYHQTILDLTADRTWSLKDSEALPVLISDNLVDEGRKIETEETAVPLDYPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4D3</accession>
    <name>A0A2G4F4D3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56571">
        <property type="protein sequence ID" value="PHX56571"/>
        <property type="gene ID" value="CP500_004815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="23225" checksum="DA26E2F249D0F550" modified="2018-01-31" version="1">MTYTTPKLLSFEEFIAQYGDNTRYELIDGELREMEPTGPHEAVSGSIAGRIYVEIFRDNFNWLVPKTCLLKPLYAEATALRPDIVVLDQAELRQEPLWQKEPVICNGSTIKLVAEVVSTNWQDDYARKVEEYAFLNILEYWIVDFRGLGGWQFIGNPKQPTFTVCQLVNGVYQQQQYRLGDTISSYLFPNLQLRLDDIMPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4H9</accession>
    <name>A0A2G4F4H9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56645">
        <property type="protein sequence ID" value="PHX56645"/>
        <property type="gene ID" value="CP500_004340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7626" checksum="8CCE43E820A0EB02" modified="2018-01-31" version="1">MNTKLIESLVQIIQTLSEEEQLLIQAKLFSNIPYPSIVEITQLAQSGGAFQFLDDEPDIYTLDDGEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4J5</accession>
    <name>A0A2G4F4J5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">VKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_005705</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VKOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56407">
        <property type="protein sequence ID" value="PHX56407"/>
        <property type="gene ID" value="CP500_005705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12916">
        <property type="entry name" value="VKOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012932">
        <property type="entry name" value="VKOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044698">
        <property type="entry name" value="VKOR/LTO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038354">
        <property type="entry name" value="VKOR_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07884">
        <property type="entry name" value="VKOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00756">
        <property type="entry name" value="VKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="VKc" evidence="11">
        <location>
            <begin position="11"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX56407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="306" mass="33525" checksum="A8C889167B592947" modified="2018-01-31" version="1">MRRQRSLPWIHRYSRPIMAGIATIGAAITAYLTAVKLSQGAVTCPIAGCDIVLSSPYAYVFGLPLSLFGFLGYLSMIIFAVAPLFVNPSEQKSLRSTLESWTGLFLFAGGTAMMIFSGYLMYVLTVDIKAACIYCIASALISTSLFFLALIGREWDDIGQLFFIGILVSMLVLISSLALYADVNNLGTARETSMNTTTISGPSEIALAQHLKRVGAKMYGSFTCSHCQMQKDSFGKEAARIFNYIECNPQGKNARPDLCQAAKIQGTPTWEINGKFYQGQKSLKELADLSGYQGSREFQNLSNPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Q5</accession>
    <name>A0A2G4F4Q5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_003920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56764">
        <property type="protein sequence ID" value="PHX56764"/>
        <property type="gene ID" value="CP500_003920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="165"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="292"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="397" mass="45195" checksum="418FEA7D0973B23E" modified="2018-01-31" version="1">MIVLEFKLKGKPQQYRVIDEMIRTTQFVRNKALRYWIDNQGVKLLDLYKQCAIMAKEFEWARKLNSTARQASAERAIFAIQRFFSNCKAKKPGKKGYPQFKKHTRSVEYKTSGWKLSTDKRCLTFTDGFAAGTFKLLGSRDLHFYSPKEIKRVRVIRRADGYYAQFCVNVERIEEVIPTGKAIGIDVGLNLFYTDSNGETMTNPRHLRKREKALKRLQKRVSRKKKGSSNRKGAINRLGRKHLKVSRQRKDFAVKTALCVVKSSDFIAYEDLQVRNMVKNHKLAKSISDAAWSQFAQWLQYFGKVYGKTVVAVAPQYTSQDCSSCGNRVQKSLSVRTHICSCGTVLDRDHNAALNILAKGLKQVGIILNTVGHTGINAWGQTDLYSLVVTSTGKLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4V4</accession>
    <name>A0A2G4F4V4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase C14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56768">
        <property type="protein sequence ID" value="PHX56768"/>
        <property type="gene ID" value="CP500_003940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="618" mass="66804" checksum="38CA949812E95E0E" modified="2018-01-31" version="1">MKHHACIAIGINQYQLLQPLSYAQEDAEAVYTFLVEEAGFSRDECLLMTDSSPSLWGNSTYPNRENILKLTENLCAEHLQQGDLLWCFFSGYGVSHEGKDYLMPVDGNPADIQGTGIPVELLLNTLKKAPTETVLVLVDMNRSQIVKAGETIGVQTAELARNLEIPTMLSCRPNQVSRETSALRQGFFTTALLEGLRSGQCMTLKGLDRFLTDRLPELCDHHLRPKQEPLMVVNPPGKAHLVILPDVAVVANAEAAGRNGSVTVGAESNGFDRQRMGAATAQMDLPPATRKSQDLGTEMPSQMPVSNPVGSAGGGGDRSNLQKPEDLGNGAADKSFLQQLILWSGATAAILLLGVFLTNRSIFMAQQEGSPKLTAENAQNRPPKKSGVKPVTPGAGVSQNQPQAVSVGTGTKPQPSSQQVWAEAKTLLKDSSASSFNNAVRKARSIAPTDPLYPQTQQDIERWSLTILDIANGRAARGDFLGAIGAAKLMPDANKPIYNQSKEAIVQWQDLSKQQQLNASLISAAKTKIKRGEASSYSKAIEQVNKIQPGEPLHTEAQRLTGEWSETILKIAQLRSSQGKLKDAVESASLVPSGTKSYQRAQKAIAEWKSKLKPQKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Z4</accession>
    <name>A0A2G4F4Z4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LytR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_003695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56781">
        <property type="protein sequence ID" value="PHX56781"/>
        <property type="gene ID" value="CP500_003695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027381">
        <property type="entry name" value="LytR/CpsA/Psr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13399">
        <property type="entry name" value="LytR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="129"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_C" evidence="5">
        <location>
            <begin position="372"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="468" mass="51251" checksum="5D0580AF9034A97F" modified="2018-01-31" version="1">MPAQKNPNQDPTQQPAAQTSTSKSTEPHRGRWLGFGFGLAGVAMLSATAGALLAVSLSTTPLQQQKLTPEEAAVFSQGDMAKLSMKMPELTRPVNILVLGLKVLSSDINGQPDKDKGYEVWENSFKGLTDTMLLVRFDPQNKKLSVLSIPRDTRAYVEGRGEVKINEANYYGGPASSAKSVSGLLGGVGIDRYVTLNIQGIKSLVDAIGGITINVPKDMKYTDESQHLYIDLKAGKQHLNGEQIVQYLLYRHDNLGDIGRVQRQQLLMRAFVEQEVNVGLLSRLPNILSVIQSHIDTNLSIEELVALAGFAIKTDRSSVQMLMVPGKFSDAKDYKASYWLPDQNAIETLVAEHFDFGQNTWTIENADATFLKVAIQDSTGNQAAVEEFVKTLTQAGYRNVHVYKDWPEALEVTTFVAQDGDIKGAQAIRQSLGFGDVLVESTGSLQSDVTIRLGKDWLSKKSQSGRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F513</accession>
    <name>A0A2G4F513_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56862">
        <property type="protein sequence ID" value="PHX56862"/>
        <property type="gene ID" value="CP500_003030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="34"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="12591" checksum="292EB62E46C50417" modified="2018-01-31" version="1">MKARIFPLEADVRFSDEAATVTEIIQTENASIAIWGVKPGQIVQAHCHPDGQDTWVMLRGTLTYYLGNGQSQTLNAGEVAIAEKNQIHGAVNDNSEDAVFISIYSAPQIGYEKASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F517</accession>
    <name>A0A2G4F517_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56893">
        <property type="protein sequence ID" value="PHX56893"/>
        <property type="gene ID" value="CP500_003110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="152"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="466" mass="53247" checksum="C4F86C8B47DB9732" modified="2018-01-31" version="1">MLKFADDIVFAKTGQHLDDLQEAVLRGTLQRETYKEIAKDFDCSESRIREIGSQLWQILSEELGEKVTKSNFRSAMERFQVSNVSNFAQNVNEQHISGSFNTCGQARHPPNIPNQPPPNQETSNTKQPETPHQDLSEMPELGTFFDRTHELQTLTTWILQQNCRLIAITGISGIGKTSLAVQLVQQIKDEFEYTVWCTLDEFPTIDKFQPNLIQLFSKSENLDSSPTNQKRLPLIKYLQNHRCLIVLDDVHNLFCSGESAGKYKPECEEYRSLFKQIEKLSHQSCLLLIGWEQPREVTQVKNQNTPIRTLQLKGLDIAAAREILRDYGLAESDNSETLIHRYQGNPLWLKSVASLIQELGGGVTELLPNDTILLPEDLKDVLQQQFDRLSELEKQVICLLARESQPVDRAKLLENDIIPVSDLANALQSLSRRCLIEQQANFYTLSPIMKQYIKTRLSHLTNIDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F592</accession>
    <name>A0A2G4F592_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56916">
        <property type="protein sequence ID" value="PHX56916"/>
        <property type="gene ID" value="CP500_002755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025528">
        <property type="entry name" value="BrnA_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14384">
        <property type="entry name" value="BrnA_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="93" mass="10783" checksum="36A9780B8701A512" modified="2018-01-31" version="1">MSRNDLNNTSGTNWSALESRSEQNIDYSDIPPLTDEFFERATLRIPADQAHNLVQLDPDVKQWFQAQGEEYKTLINKVLRQYIENNKTQHSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5M5</accession>
    <name>A0A2G4F5M5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57084">
        <property type="protein sequence ID" value="PHX57084"/>
        <property type="gene ID" value="CP500_002050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10542" checksum="2FD6B84F8A60D7A3" modified="2018-01-31" version="1">MAVLECVKPGAKLGQIILAVDLTVAGAVDRILAKIQDLGYDPEIRHVNYPSGVHVLAILKDEQHSEAVDDDYLLEDWLQVRSEINADAVHLWRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5S1</accession>
    <name>A0A2G4F5S1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rplM</name>
        <name evidence="4" type="synonym">rpl13</name>
        <name evidence="7" type="ORF">CP500_001680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57134">
        <property type="protein sequence ID" value="PHX57134"/>
        <property type="gene ID" value="CP500_001680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_L13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="151" mass="17010" checksum="24835343714DFBC9" modified="2018-01-31" version="1">MNKTYVPTHDSLEHKWYVVDAADQRLGRLATEVATYLRGKHKPTYTPSMDTGDFVIVINADKIAVTGKKRTQKIYRRHSGRPGGMKTETFAKLQARLPERIVEEAIRGMLPHTSLGRQLFTKLKVYAGPEHPHAAQKPEELIVHTIPGGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5V2</accession>
    <name>A0A2G4F5V2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fumarate reductase iron-sulfur subunit</fullName>
            <ecNumber evidence="6">1.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_001580</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a menaquinone + succinate = a menaquinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:27834"/>
            <dbReference type="Rhea" id="RHEA-COMP:9537"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="ChEBI" id="CHEBI:16374"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="EC" id="1.3.5.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="6">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.4" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57119">
        <property type="protein sequence ID" value="PHX57119"/>
        <property type="gene ID" value="CP500_001580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102040">
        <property type="term" value="F:fumarate reductase (menaquinone)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 6" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="152"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="338" mass="37986" checksum="143BD493496EB9F9" modified="2018-01-31" version="1">MQVRFNVVRQNQNEPPRVHAYTLEVEESNTILDCLNSIKWEQDGTLAYRKNCRNTICGSCSMRINGRSALACKENVGSELARLDKIANFSSAEKPIDLIPEITIAPMGNMPVIKDLVVDMTSFWDNLEAVDPYVSTSARAVPEREFLQTPEERSKLDQTGNCILCGACYSECNAREVNPEFVGPHALAKAYRTIADTRDSNTENRLEKYNQGTEGVWGCTRCYYCNSVCPMEVAPMDQIGKIKQQILDRKDDQASRSIRHRKVLINLVKEGGWIDERKFGIEVVGNYFRDVKGLLSLGPLGLRMIARGKFPLSFESSEGTKTIRDLIESVQSLENSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5X9</accession>
    <name>A0A2G4F5X9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmC</name>
        <name evidence="5" type="synonym">rpl29</name>
        <name evidence="6" type="ORF">CP500_001775</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57149">
        <property type="protein sequence ID" value="PHX57149"/>
        <property type="gene ID" value="CP500_001775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_L29_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="92" mass="10367" checksum="BF70D9BD5E69C4C3" modified="2018-01-31" version="1">MSLPKIKESRDLNDAEVAEQILAVKRQLMELRLFQATGRMDKPHLFKHAKHRLAQLMTVERERQRVAEAAAVAEKLAQSIETEQTASTAAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F600</accession>
    <name>A0A2G4F600_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA interferase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Toxic component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PemK/MazF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57178">
        <property type="protein sequence ID" value="PHX57178"/>
        <property type="gene ID" value="CP500_001230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR033490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="12763" checksum="8A670F81CF2B0DAD" modified="2018-01-31" version="1">MRRGEIWLVALEPTVGAEIGKTRPVVIVSDETVGILLLEVIVPITDWKQRYSERNWMVRLEPSRENGLAKLSAADTFQVRSVSQQRFVRQLGVLSDTIMAEISEALEIVLDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F649</accession>
    <name>A0A2G4F649_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminotransferase</fullName>
            <ecNumber evidence="2">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_001310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57219">
        <property type="protein sequence ID" value="PHX57219"/>
        <property type="gene ID" value="CP500_001310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="31"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="387" mass="41950" checksum="3BF7D137C9897434" modified="2018-01-31" version="1">MKLAARVGEVPPSITLAIAAKAKAMKAEGIDVCSLSTGEPDFDTPEHIKAAAKQALDSGKTKYGPAAGEPELKAAIARKLRNDNNLHYQPENIIVSNGGKHSLYNLMMALIEAGDEVIIPAPYWVSYPEMVKLASGKPVIVQTDASTGYKITPEQLSQAITPQTKLFVLNSPSNPTGMVYSPAEIKALAEVIVDRDILVVSDEIYEKIIYDGAQHVSIGSLGQEIFDRTIISSGFAKAYAMTGWRVGYLAGPIELIKATSIVQGHSTSNVCTFAQYGAIAALESSQESVEKMRLAFADRREVIFQLLDAIPRISCIKPDGAFYMFVNISKTGMNSLQFCDALLEQQQVAVIPGIAFGADDHIRLSYATDLGTIKKALERLDKFVRHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F652</accession>
    <name>A0A2G4F652_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56967">
        <property type="protein sequence ID" value="PHX56967"/>
        <property type="gene ID" value="CP500_002455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="166" mass="18610" checksum="C19D6FDB67940848" modified="2018-01-31" version="1">MVTATIISDNLALEEFIAAPPDRMELVDGQLVEKNGMTPKTGKIQSRLSRYWGDYKDSSGQGGETYVEVPCRTNRQIRRPDVAYLTPELVAQFGNIATLPQSFPLIAEIVSPTDIAEDVFLKAQEYLESCCQEVWLVFPESCLIFVMTQNQIFTFRSGDIAILNHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F662</accession>
    <name>A0A2G4F662_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_001075</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57262">
        <property type="protein sequence ID" value="PHX57262"/>
        <property type="gene ID" value="CP500_001075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000813">
        <property type="entry name" value="7Fe_ferredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00354">
        <property type="entry name" value="7FE8SFRDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8053" checksum="DB9F98583B7AC932" modified="2018-01-31" version="1">MSHTIVTNICEGVADCVGACPVACIQPGPEKNVKGTDWFWIDFDTCIDCGICLQVCPVEGAIVADERPELQQTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6B6</accession>
    <name>A0A2G4F6B6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57334">
        <property type="protein sequence ID" value="PHX57334"/>
        <property type="gene ID" value="CP500_000710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="12141" checksum="7517EAD5CDBBFBA9" modified="2018-01-31" version="1">MTTTVSVEHIERTPGIRGGKPRIVGTRIAVQDVMVMHLKMGYSLLEIATKYDLLVAAVYDAMAYYYDHRQAIDREMAEDDAFVDEFMRQNSGRLQAKIKELKGESAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6F8</accession>
    <name>A0A2G4F6F8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_000745</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57340">
        <property type="protein sequence ID" value="PHX57340"/>
        <property type="gene ID" value="CP500_000745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="PHYTOCHROME_2" evidence="4">
        <location>
            <begin position="58"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="260"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="332"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="377"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="458"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="513"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="587"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="655"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="871" mass="99293" checksum="6AD809455DF8DBAB" modified="2018-01-31" version="1">MLNGTFLVAIGVLFLLVISFYFKQEVARRRRAEGVLRQQTDRERLVNQIAQHIRQSLDLDEVLETTVADVQRFLEADRVLIYRIWPDGTGSAINETVLPPYPVILGTSFPEEVFPREYHQAYSLGKTRLITNVEQADVEPCLTDFVQQFGVKAKLVVPILQENREVEGSHSVPDLWGLLIAHQCDGPRTWETWEVQLMQQLATQVAIAIQQSELYQQLQQLNAELEQRVQQRTEELAEANVALRGEIAERQRTEVELRHTNHTLQTLITASPRAIFTLDVEGYVKIWNPAAEQMFGWTEAEVINHPNPIFLDDPLEDYSTLRTNLLQGTTYSRVELRRHKKDGSAIDIIFSAAPLKNSENQIDGIVAVIADITEQKQQAEQVRLLQSVVVNTNDAVVITEAEPINEPGPRIIYVNEAFTQITGYSPEEVLGKTPRILQGTKTDRVELDKIRTALSRWEPVTVEVINYRKNGSEFWNEFSIVPVADQIGWYTHWIAIQRDTTGRKQAEQALRQSEERFRSLIENALDIIMILNTEGTIRYVSPSVEKVLGYLVSELVGKKIFEPIHPDDFTTTYYSFTNTLQSAEINRPIEFRYRHKDNSWRTLEAISQPFIDNAATTQIIVNARDITERKRLDEIRLALEREQELSILKTRFFSMASHEFRTPLSTALAAAQILENSPDEWNDSQKRLRNLHRIQDSVRNMVQLLDDILTINRAETGKLEFNPKLLVLEQFCHQFVEEMRLSAGSQYTLTFTCEGNPIPVCLDEKLLRSILSNVLSNAIKYSPKGGNVHLGLEFQPYAVILRVQDRGIGIFPEDIKQLFEPFQRGKNVRTIPGTGLGLIVVKKCVDLHQGSIQITSEVGIGTNCVVTLPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6G5</accession>
    <name>A0A2G4F6G5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_000115</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57384">
        <property type="protein sequence ID" value="PHX57384"/>
        <property type="gene ID" value="CP500_000115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="34"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="8">
        <location>
            <begin position="380"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="55"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="811" mass="91440" checksum="40B2C2C1009C4D7B" modified="2018-01-31" version="1">MTDEFDPNFSTHSTSSQSELGAVLREQACQKIRDSLREAQKDMANWQGGPLAVSAVPGAGKSTGMAAAAAIAIARNRLHSRRQLVVVTFTRSAAANIKIKIRERLKELSLPQGGFVVNTLHGLALNIARRHPSLSGLNLENSTLVNTTQSHRLIRACVELWIAENPRRYQTLLEGQQFDGEETERMRRQSVLRTEILPQLANTVIHEAKSSGLFPEDLLEMGAMSFGDSYEILAVAGGLYQKYQALLRSREFIDYDEMILAALRVLADPRARAIEQKQVFAVFEDEAQDSTPLQTELLATLAEDPDHPELLPNFIRVGDPNQAINSTFTPADPIYFNNFCDECKEQSKLAEMDVAGRSSQIIIDAANFILEWVNRSELAGTEPPFRHQIIEPVPRDDQQINANPAPIGRGLELYTPRDIYHTIELIGKRVVQLVEEFLPAGFEWGKSEKYLEFDGEVSDEENQAKLPLEYLKSMAVLVRENKQGKLIKQVLENPQKYGLTVDLSKYGIKIEDVGERDRHSQVPWEILTLLQFLDRPHSPDYLKAALKILSDRQLIPKQDYNAFTTSPEQFLYPGPLDPKQSDPVKKCRYFCCSLLQARLELPPYQIISFLALALQYDQTELATADKLAERVAIQTIGNNSMSNILGVLSEIVTSERFEPVEAEEKIEERYTSKGQLTIITMHKAKGLDWDCVFLPFLHDQIIPGSLRVLPQAKFLGDFTLAEVARAQIRASLHKKDAFSNLGEAWEQAGYLKTAEEFRLLYVAMTRAKSLLWMSAEKKGPFTWNKPDNLQELKPCPVMPVLKQKFPDHVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6L4</accession>
    <name>A0A2G4F6L4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycerol-3-phosphate acyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Acyl-PO4 G3P acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Acyl-phosphate--glycerol-3-phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">G3P acyltransferase</fullName>
            <shortName evidence="10">GPAT</shortName>
            <ecNumber evidence="10">2.3.1.275</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lysophosphatidic acid synthase</fullName>
            <shortName evidence="10">LPA synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">plsY</name>
        <name evidence="11" type="ORF">CP500_000415</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:34075"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="2.3.1.275"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably interacts with PlsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PlsY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.275" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57433">
        <property type="protein sequence ID" value="PHX57433"/>
        <property type="gene ID" value="CP500_000415"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01043">
        <property type="entry name" value="PlsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00023">
        <property type="entry name" value="TIGR00023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX57433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="226" mass="23757" checksum="CFD81B34496A787E" modified="2018-01-31" version="1">MASWIILNGALLIAAYLLGSIPTGYALGKWMLGIDIREVGSGSTGATNVLRTLGKWPGLGVLLVDVLKGVSAIGLIRYIYSLNFTQQLATTAGLENTETIIPWMATLAGLFAVLGHSKSIWLGFTGGKSVATSLGVLLGLYWPVGLGTFGIFGIVFAVSRIVSLSSIMGAMSVAGLMFALNQPLAYILFGIAGGVFVIVRHRSNIQRLLNGTEPRIGEKLETAASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6M8</accession>
    <name>A0A2G4F6M8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA/RhaT family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57399">
        <property type="protein sequence ID" value="PHX57399"/>
        <property type="gene ID" value="CP500_000210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="16"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="163"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="302" mass="31310" checksum="1E88BF7B8747909E" modified="2018-01-31" version="1">MNLPKQIPNWSIAPILIIGILAVSTSSILIRLANSSANSGGLGFSLVLAASRLSLSALILLPAWSKVQWNRLQPGARRYGAAAGLCLALHFALWITSLSYTSIAASTALVTTNPVWVALLSRFWFGEKLSKLSVAGIAVALGGTIAIALGSASGSGDGSSVMLGNFLALAGSWAVSLYLLCGREAQRRGLGIGGYVAIAYTVAAIVLLPLPLVFKTSYTGYPHIVYFYILLTAALPQLVGHTILNWAVVRVSPTLVSLAILFEPVGASCLGYLVFGEVPGLSVLVGAGVLLFGVAIGIFGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUF5</accession>
    <name>A0A2G4EUF5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000254">
        <property type="protein sequence ID" value="PHX53165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53165">
        <property type="protein sequence ID" value="PHX53165"/>
        <property type="gene ID" value="CP500_022955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="292" mass="33746" checksum="BF2F4ECEB1848888" modified="2018-01-31" version="1">MATLKQLYDENEGDFIDAMVNRFNFSGKKDLVFRSRFIKDNDGCIHQKLAQQSAKHLIDDESQDASQIYRQTLASICDKMEEMGCPPSKGADRWKNCRRWLREEMFEQCKEQGLIKPRTIEECWNELKTKVKNSQPTKAGEMQSELIVEKWEARLSDMAARRNIKRQEFPPNSDLTYRVISPQVGHLILFEREPNGTIVCLCPSEYSPSDYPGKETVLPHPDSDYESFGSDELGWEQLLAVITPELPPFPWLEDSRQEALEVNQEHLAGILDYVNGQTNAEVLYTEYWVVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUH2</accession>
    <name>A0A2G4EUH2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000247">
        <property type="protein sequence ID" value="PHX53189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53189">
        <property type="protein sequence ID" value="PHX53189"/>
        <property type="gene ID" value="CP500_022810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7047" checksum="2DD6437879BA1C39" modified="2018-01-31" version="1">MRRHLKSTNQIDNLVATHPTNVSVGSKLGGAFGTRKYLEFETNNVDLWVEKLVYMLAQIPMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUL9</accession>
    <name>A0A2G4EUL9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000237">
        <property type="protein sequence ID" value="PHX53224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53224">
        <property type="protein sequence ID" value="PHX53224"/>
        <property type="gene ID" value="CP500_022645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="6912" checksum="90E27A37B2C7110F" modified="2018-01-31" version="1">MGSIEDTAVPINVNNQVKPIVRQGLKPLSQSESPLKRTEELISPLERTFAIRQGIHSLAGFQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUM4</accession>
    <name>A0A2G4EUM4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4407 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_022960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000254">
        <property type="protein sequence ID" value="PHX53166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53166">
        <property type="protein sequence ID" value="PHX53166"/>
        <property type="gene ID" value="CP500_022960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025519">
        <property type="entry name" value="DUF4407"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14362">
        <property type="entry name" value="DUF4407"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="428" mass="48812" checksum="D531341FAB1C0578" modified="2018-01-31" version="1">MQKLLQWIAGADRDLLEQSHAGDRMKYSAIGFSILLTSFAGILSGGYAFYTTFKNPLSSLVLGIFWGLFIFSMDRLIVLTTRKEKKNVVKQILMGLLRIFVAVLIAAVVAKPLELKIFEKPILAEISKENARVAIEIEKTLNQGMPEIPQLQAEKQRLEKTISEKEKYRDLSCKKTIEEAEGTSGTGKEGKGPVYAEKQAMCQQLEQELEVLRSKTEPRLAETRQRLEKLQNEKDRKSEKIQTTQENADDIITQLSTLERLGKNNPAIAHASHAISLLFIVLDTAPIFAKLLSKRSPYDAMLERCEHELIENADLEIANINEIVRRHKQFELNQHQEALEKASTSDAMSEVLQKVAEEIVKHTKEQLLKLVSKYQITHAMKTAVKQQQKSARQNLYRARNERQKTHQKANKFMAYATETLKKFVTRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUX2</accession>
    <name>A0A2G4EUX2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53339">
        <property type="protein sequence ID" value="PHX53339"/>
        <property type="gene ID" value="CP500_022055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="55"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="249" mass="27571" checksum="8D56DD52EF11FF45" modified="2018-01-31" version="1">MNSHSTASPENKEILPGEVFINTADFDTGIRRLLPKYDEMLDVLVGCISSTNHRILELGCGTGELSLKVLQRYPSAEIVALDYSPRMLDFARAKVESAGYGSRWTGIELDFGEWANNPNFSGLRDKFDGCISSLAIHHLDDEMKLKLFERICESLNPDGCFWNADPMLAESAKMQKVYQAAREDWAASQGETLAAIRGSVGMSVSYGYSNPDRLATLYAHLEMLAQAGFEAIAVPWKYYGMAVFGGFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV17</accession>
    <name>A0A2G4EV17_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF427 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000205">
        <property type="protein sequence ID" value="PHX53383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53383">
        <property type="protein sequence ID" value="PHX53383"/>
        <property type="gene ID" value="CP500_021795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_9" evidence="1">
        <location>
            <begin position="31"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="164" mass="18693" checksum="79D0C5BC91175334" modified="2018-01-31" version="1">MNSDRIEPGVGQESVWDYPRPPRLEASTKHVQIIFNGVKLADTHRAFRVLETSHPPSYYISPDDIQMQYLHTTSQGSWCEWKGKASYCTVTVGDKQAVNVGWFYTHPNQVFEAIKDYVAFYPGRMDACYIDEELVQAQLGDFYGGWITKDIIGPFKGGMGTWGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV58</accession>
    <name>A0A2G4EV58_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF362 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000198">
        <property type="protein sequence ID" value="PHX53432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53432">
        <property type="protein sequence ID" value="PHX53432"/>
        <property type="gene ID" value="CP500_021530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007160">
        <property type="entry name" value="DUF362"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04015">
        <property type="entry name" value="DUF362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF362" evidence="1">
        <location>
            <begin position="41"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="319" mass="34910" checksum="A16094562A3A5280" modified="2018-01-31" version="1">MPAVSLIRADLYDRQILQKSLENLLAPLGGMSAFVKKGDRVLLKPNLLTGSRPTKECVTRPELVYCVAKMVIEAGGKPFLGDSPAFGSAIGVAKANGYLPLLEELNLPVVEFQGKRYETVSDEFNHLRLCKEAMEADVVINLPKLKSHVQLTVTMGVKNLFGCVPGKMKAWWHMEAGKDSARFGEMLVETARTINPNLTILDGIIGHEGNGPSGGEPKFLGILGASSDVFALDRTVVEIINVDPASVPTVAAAIKLGLCSNLEAIDFPLLQPESLKVLDWKLPEKMMPIDFGMPRVVKSAFKHLYIRFIKEKFSIKTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV64</accession>
    <name>A0A2G4EV64_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000198">
        <property type="protein sequence ID" value="PHX53433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53433">
        <property type="protein sequence ID" value="PHX53433"/>
        <property type="gene ID" value="CP500_021545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="360" mass="40946" checksum="DC2B54354C5C5474" modified="2018-01-31" version="1">MSVAIITGAAGLIGSEACKFFAKQGFDIVGIDNNMRQFFFGADASTNWNRQLLEKSLGGKYFHLDVDIRDYEAITNIFQRYGEDIELVIHTAAQPSHDWAARAPKIDFTVNANGTLNLLEVTRLYSPKAVFIFTSTNKVYGDTPNKLPLVELEHRWEIEPGHTYEGGIREDMSIDQCLHSLFGASKVAADILVQEYGRYFNMNTACFRGGCLTGPNHSGTQLHGFLAYLMKCAVTGTPYTIFGYKGKQVRDNIHSADLISAFYEFVKAPRSAQVYNMGGGRYSNCSMLEAIQMCETIAEREFNWTYAEDNRMGDHIWWISDNGKFASHYPDWKMKYNVKQILQEIYECNRERWLKEVPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVD9</accession>
    <name>A0A2G4EVD9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Trigger factor</fullName>
            <shortName evidence="6">TF</shortName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">PPIase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tig</name>
        <name evidence="11" type="ORF">CP500_021140</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="6">About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 8">Belongs to the FKBP-type PPIase family. Tig subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000187">
        <property type="protein sequence ID" value="PHX53503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53503">
        <property type="protein sequence ID" value="PHX53503"/>
        <property type="gene ID" value="CP500_021140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00303">
        <property type="entry name" value="Trigger_factor_Tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005215">
        <property type="entry name" value="Trig_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008880">
        <property type="entry name" value="Trigger_fac_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037041">
        <property type="entry name" value="Trigger_fac_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008881">
        <property type="entry name" value="Trigger_fac_ribosome-bd_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036611">
        <property type="entry name" value="Trigger_fac_ribosome-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30560">
        <property type="entry name" value="PTHR30560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05698">
        <property type="entry name" value="Trigger_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05697">
        <property type="entry name" value="Trigger_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003095">
        <property type="entry name" value="Trigger_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102735">
        <property type="entry name" value="SSF102735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00115">
        <property type="entry name" value="tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 6 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="10">
        <location>
            <begin position="169"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="437"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="475" mass="53294" checksum="A2CF60F68117E4E5" modified="2018-01-31" version="1">MKVTQEKLPASQIGLEIEVPSEKSKQAYEQVIKQFAREINIPGFRKGKVPRQVLLQRIGQTRLKATALENLINDSLQKALEQEKISAIGSFELAIEFDELLSKYDPEQPLTFTAKVDVEPEVKLAQYTGLELKAEEASYDEAQVDEVLQKYRSDKAALIPVEGRPAQLGDMALVDFSGRFADAPEGETPAEIPGGEAQDFQVELSENQFVPGFIQGMIGMNPGETREVAVQFPDEYSSEELAGKSAVFTITLKELKEKELPELDDDFAQEVSKSEFETLAELRESLETRFKGDQERKITANKERAILEALVQLVEVEIPETMLDREVDFLLNQQATQLKNYGIDINQLFTEENMGPMRERLRPEATDKIKQSLALAEIAKLESLSVEQAEITAEVARVRQQFPKGNFDPERLQEFVREDLLKQKTLTWLEEHGTIELVPEGSLTPPVDESDDDDADDAETSEASTVVDVEVVGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVG9</accession>
    <name>A0A2G4EVG9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8 9">Elongation factor Tu</fullName>
            <shortName evidence="8">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">tuf</name>
        <name evidence="11" type="ORF">CP500_021070</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000184">
        <property type="protein sequence ID" value="PHX53524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53524">
        <property type="protein sequence ID" value="PHX53524"/>
        <property type="gene ID" value="CP500_021070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="10"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="409" mass="44680" checksum="05F7D4A986202C40" modified="2018-01-31" version="1">MARAKFERNKPHVNIGTIGHVDHGKTTLTAAITMTLSALGQAKGKNYADIDAAPEEKARGITINTAHVEYETTDRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLAKQVGVPSLVVFLNKEDMVDDAELLELVELEVRELLSSYDFPGDDIPIVTGSGLKALEAMLANPKAIKGDDPWIDKIYALMDAVDDYIPTPEREVDKPFLMAVEDVFSISGRGTVATGRIERGKIKISETVEIVGLKDTRSTTVTGVEMFMKSLDEGLAGDNVGLLLRGIQKADIERGMVIAKPKSILPHTLFESEVYILKKEEGGRHTPFFSGYRPQFYVRTTDVTGTIKQFTTDDGKEVEMVMPGDRIKMTVELINPIAIEQGMRFAIREGGRTVGAGVVSKILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVN4</accession>
    <name>A0A2G4EVN4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53594">
        <property type="protein sequence ID" value="PHX53594"/>
        <property type="gene ID" value="CP500_020695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="13853" checksum="B4B58B1A1F2C60DC" modified="2018-01-31" version="1">MNLSDLQDLVAIPSNDEKLGELVSNDKYKNQFSQLKYAVDILSKEKYSKNLSKLKDVVNILSNGQDLVKISSAQLVCQLSDEQYRKDLSNLKEVVDMFYNESDKENLSQLLREIGLRYSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVS6</accession>
    <name>A0A2G4EVS6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Alpha-amylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_020910</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000179">
        <property type="protein sequence ID" value="PHX53550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53550">
        <property type="protein sequence ID" value="PHX53550"/>
        <property type="gene ID" value="CP500_020910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013776">
        <property type="entry name" value="A-amylase_thermo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001021">
        <property type="entry name" value="Alph-amls_thrmst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="8">
        <location>
            <begin position="6"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001021-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001021-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="492" mass="56576" checksum="15199577A0AEE4C4" modified="2018-01-31" version="1">MSELNGVMMQYFHWYTPADGNLWNQLAKSAKDLAKIGVTSLWLPPAYKGTSGGMDVGYGVYDLFDLGEFDQKGSVRTKYGTKDEYLRAIKAAQDCGIKIYADVVFNHKLGADEEEEAEATPFNPDNRNDTVGEYQKIKAWTHFTFPGRCQTYSSMEWHWWHFDAIDYNAYDTNANAIYLLKGKEFDRNVDLEKGNFDYLMGCDLDMQNPEVTGELKYWGEWYVDTTNVDGFRFDAVKHVSAKFFQEWLEHVRNYAKRDLFAVGEYWSYEVEALHNFITVTDGKVSLFDAPLHYNFHAASKAGNDYDLRTIFDGTLVQQQPTLAVTLVDNHDSQPLQSLESVVESWFKPLAYALILLRREGYPCIFYPDYYGDHYKDTANDGNEYEIWLDKHQWILDKFLFARQTYSYGNQYDYFDHANTIGWTRLGDEEHPGGMAVVLSNGGDGTKFMEVGQPNRTYIDITESIKESIATNDEGWADFRCNAGSVSVWVPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVZ6</accession>
    <name>A0A2G4EVZ6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type-4 uracil-DNA glycosylase</fullName>
            <ecNumber evidence="3">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_020085</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53703">
        <property type="protein sequence ID" value="PHX53703"/>
        <property type="gene ID" value="CP500_020085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005273">
        <property type="entry name" value="Ura-DNA_glyco_family4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00758">
        <property type="entry name" value="UDG_fam4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="9">
        <location>
            <begin position="63"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="25740" checksum="774401C8EE3ECF84" modified="2018-01-31" version="1">MSSDLQLSLFDSSQSASFQTDSIPTNAKIPIPPGTYQNIEQIAEHCNRCHRCELGNSRTHAVIGRGNPQAKILIVGEAPGQNEDETGLPFVGRSGQLLDKILESVGLNTETDVFIANVIKCRPPNNRPPTVKEIEACKPYLLEQIRILDPKIILLTGATALKGLLSDKRPISKIRGQWIEWENRLCMPIFHPSYLLRNPSREPETPKWFMWQDMQVIKAKFDELKEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW02</accession>
    <name>A0A2G4EW02_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000165">
        <property type="protein sequence ID" value="PHX53668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53668">
        <property type="protein sequence ID" value="PHX53668"/>
        <property type="gene ID" value="CP500_020290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="16"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="21522" checksum="E7713294C5A0E521" modified="2018-01-31" version="1">MRSAYPSTRLTVADLEQLQGILCEAQLDYQLELADGKIIVRGPSDIVSSEIGLEFGRLLLNWVKPRKLGRVFESSGGFILPNSDLRVPDVSFVVASRLKQSKRYFAELVPDLVVEIKSESDRLKPLREKLLSFIEHGAKVGILIDPDDRTVTIYRPETEPVILRNGDIISIPELLPGWEVPVAELWPIEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW22</accession>
    <name>A0A2G4EW22_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53752">
        <property type="protein sequence ID" value="PHX53752"/>
        <property type="gene ID" value="CP500_019760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="194"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="462" mass="51119" checksum="7E1034A4ECE5F8BB" modified="2018-01-31" version="1">MLMPASSEFVKLCRSQVAITVSLGATFSAVYLTEELIEGSEAKLVPIAVYPETSESWEENQGLRLQSPASSAVKPIQRLLANPTPSQEASAMGAIEPESLSGFDSNANQCQGPENSWLSRRQIVTPLIHEGAVMGLLVSGRQDRSWNDREDAQMQQIARTLALASILDQRSQWMQQELRQQGQIQAQVYDTMQNLLHQFKSPLTALRTFGKLLVKRLVPEDKNRNVASSIVRESDRLQELLLQFDRTVDIGEANRRLPSGNSDREMSKVELNRQSPLSLSPVTNFDESCSVASVLKPLLMSAEAIASERKLKLVADIPVDLPKVSLSDRALQEVLSNLIDNALKYSQAGSRIYIKVEYKAANGDRTKKHQLPAIAIAISDTGAGIPPQDLEHLFERHYRGEKAQTEIPGTGLGLAIARDLVHQTQGEIEVFSPVNPEWLPSVGSHLYPKDRGTTFVVWLPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW51</accession>
    <name>A0A2G4EW51_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF751 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53763">
        <property type="protein sequence ID" value="PHX53763"/>
        <property type="gene ID" value="CP500_019785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008470">
        <property type="entry name" value="Uncharacterised_Ycf33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05421">
        <property type="entry name" value="DUF751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7645" checksum="E2181B6C12C464AF" modified="2018-01-31" version="1">MQDFINNVSRYPRFFITICLGIFFFLFERLKPLLEKPASAIALVTFLIATLVFVTFTLQAMLGLSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW52</accession>
    <name>A0A2G4EW52_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system MqsA family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53698">
        <property type="protein sequence ID" value="PHX53698"/>
        <property type="gene ID" value="CP500_020055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022453">
        <property type="entry name" value="Znf_MqsA-type"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03831">
        <property type="entry name" value="YgiT_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8398" checksum="AD367B1EF5A8BDBC" modified="2018-01-31" version="1">MVCDICGTEGVRVRHIPRTYSKGKDLLVIENIPVISCPHCGSSYLTAETLHEIDRIKRKRKTLAVERSVEVASFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW65</accession>
    <name>A0A2G4EW65_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative N-acetylmannosamine-6-phosphate 2-epimerase</fullName>
            <ecNumber evidence="5">5.1.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ManNAc-6-P epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nanE</name>
        <name evidence="6" type="ORF">CP500_019820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>an N-acyl-D-glucosamine 6-phosphate = an N-acyl-D-mannosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23932"/>
            <dbReference type="ChEBI" id="CHEBI:57599"/>
            <dbReference type="ChEBI" id="CHEBI:57666"/>
            <dbReference type="EC" id="5.1.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NanE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.9" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53761">
        <property type="protein sequence ID" value="PHX53761"/>
        <property type="gene ID" value="CP500_019820"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00629">
        <property type="reaction ID" value="UER00682"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047465">
        <property type="term" value="F:N-acylglucosamine-6-phosphate 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009385">
        <property type="term" value="F:N-acylmannosamine-6-phosphate 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006051">
        <property type="term" value="P:N-acetylmannosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04729">
        <property type="entry name" value="NanE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01235">
        <property type="entry name" value="ManNAc6P_epimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007260">
        <property type="entry name" value="NanE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36204">
        <property type="entry name" value="PTHR36204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04131">
        <property type="entry name" value="NanE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="224" mass="23608" checksum="8063F89291FD930F" modified="2018-01-31" version="1">MINCQIPTGLIVSCQAPTDSPLHDPIAITAIALTAVYRGASGVRIDTPAHIAAVRQQISAPIIGIWKQQLPGCEIYITPRFEDARAIALAGSDIIAIDATLRNRPVAEPDLKTFIARIHNELGKLVMADVDTIESAIAAVEAGADIVATTLFGYTAETQNQRPPGFELLAKMVEKLEVPVICEGGISSPEMAKKALDLGATAVVVGTDITGIDSKVTAYKLIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW78</accession>
    <name>A0A2G4EW78_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GHL10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_019615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000155">
        <property type="protein sequence ID" value="PHX53784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53784">
        <property type="protein sequence ID" value="PHX53784"/>
        <property type="gene ID" value="CP500_019615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003790">
        <property type="entry name" value="GHL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02638">
        <property type="entry name" value="GHL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHL10" evidence="3">
        <location>
            <begin position="45"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="542" mass="60161" checksum="A4A691AD1721254B" modified="2018-01-31" version="1">MRKPKTFFLSSLFSIGLIISFLLTPGWFPNRANALTPPLPQTSEFRAFWVDAFNPGFKTPQEVTKLIADAQRANANAIVAQVRRRGDAFYTSAIEPRTLDSNVPAGFDPLQDLIDKAHAAGMEVHAWMVTLPVVSGGKLPANHVWQQHGPNAPGRDNWAMLTSSGEAKGFLDPGHPDALDYTVSVYLDLLKRYDVDGVQLDYVRYGGPNWGYNPTAIARFNQQTGRTGKPAPADPAWMQWRRDQVTNLVRKLYVEALAIKPRVKVTAATIAWGDGPKNDEAWYKTQPYREVLQDWRAWLEEGIIDMAMPMTYQREYKPQQKLGFDHWIEYAKDHQYNRQIAIGPGNYLNYIEDTLGQIRRAEAPSAKGNHVAGTVLYSYASTNIYSNVELRSGGSGDLPRQPWKFLSQSNDWFYTALSQPSQYVDGATGKTVQTQPVWATPVGIPDMPWKSRPTLGAIAGMLQKCDSLRDSFASRTCDGANLTLQAIDAGSKVRQLRADGKGWFGAIELSPGTYQLKVDGSQIQQTVNVVAGAVTKINFGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW87</accession>
    <name>A0A2G4EW87_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FtsW/RodA/SpoVE family cell cycle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_021435</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000196">
        <property type="protein sequence ID" value="PHX53447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53447">
        <property type="protein sequence ID" value="PHX53447"/>
        <property type="gene ID" value="CP500_021435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018365">
        <property type="entry name" value="Cell_cycle_FtsW-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00428">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="399" mass="43595" checksum="3037F39C4B888C36" modified="2018-01-31" version="1">MAADIRRFIPFLDPTVSEWAAEARWLRWLTFLWLFVGLTALFSASYPIANSELGDGLYYMKRQLIAVAIGLAGFNLMIYSPLRYLIKTAQWGILMLLGLLWLTLAPGVGTTINGATRWISLGPVPIIQPSELIKPFFVLQSARIFGNWPRLTNKVRLTWLGIFGAMLLGILLQPNLSTTALCGMTLWLVALAANLPALQLGATAMGGMLLAVLSISFREYQRRRIMSFLNPWADPMQDGYQLVQSLLAVGSGGIWGVGLGMSQQKLFYLPIQYSDFIFAVFAEEFGLVGGFSLLLMLGAYATVALRVAMKARNLESQLVAIGVMVVMVGQSLLNIGVATGVLPTTGLPLPFFSYGGSSMVASFLLSGLLIRVARESSEAEVVSLDGRRKQPGKPNRHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWA7</accession>
    <name>A0A2G4EWA7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000193">
        <property type="protein sequence ID" value="PHX53467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53467">
        <property type="protein sequence ID" value="PHX53467"/>
        <property type="gene ID" value="CP500_021340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="16361" checksum="FFC28C4A3AEB5D6F" modified="2018-01-31" version="1">MKKNSWLSLTLLFLTYFCLGWKLSEFDVPPHLVWFLSVAVSLVLSVVLSFPLRDTKTLIMRWLSTDMGAFLSIIVCSFIAVIVVTWLHLFTTCLVLVSAGALARLDIQVSGFKKWQSFGILATISLTGLGLGGAIELLSTTRRLVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWB0</accession>
    <name>A0A2G4EWB0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_019730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53746">
        <property type="protein sequence ID" value="PHX53746"/>
        <property type="gene ID" value="CP500_019730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="110"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="275" mass="31143" checksum="F54D091B680246AA" modified="2018-01-31" version="1">MIDREWWTQQWLDLINTYRFKKRLERGWQYAREGKVLSIEFPNQEVIAIVQGTDPKPYQVSLGLDTLSDEDWEYVIENMSQRAIFSAKLLAGEMPHNIEDVFAAAGKTLFPLSLSDIRSRCSCPDPKNPCKHISAVYYLLGDRFSEDPFVLFQMRGRTKEQILTALRQRRGTETNENTQLNSGENSPTEDAKLLKVDRFWEYNQQLESSLVVIVPPPSSETVLDILGPIPLATDGKGTASKSSPASDALKQHFSKIYQAVSQQAVLSALKRSEGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWC1</accession>
    <name>A0A2G4EWC1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000192">
        <property type="protein sequence ID" value="PHX53477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53477">
        <property type="protein sequence ID" value="PHX53477"/>
        <property type="gene ID" value="CP500_021300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="14"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="93" mass="10836" checksum="B20067777C46D3C4" modified="2018-01-31" version="1">MQYVLIIHEVENYAAWKEVFDRAAIIRKEAGERSYQVLKYENEPNKIVHFSAWTSIADARTFFESPKLVKIREEAGVKAPEFIYLDELESGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWG4</accession>
    <name>A0A2G4EWG4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium transport protein CorA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">corA</name>
        <name evidence="7" type="ORF">CP500_019155</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Mediates influx of magnesium ions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000146">
        <property type="protein sequence ID" value="PHX53873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53873">
        <property type="protein sequence ID" value="PHX53873"/>
        <property type="gene ID" value="CP500_019155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004488">
        <property type="entry name" value="Mg/Co-transport_prot_CorA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00383">
        <property type="entry name" value="corA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="392" mass="45184" checksum="FE80B92BB1F54E07" modified="2018-01-31" version="1">MIHKNLNMSSPVGQKIKNDHDDDSYVDYFYDDPGALPGNLDLEADALPPEIVLIDYCEAKATRSELANPQEAATYLDTESVSWIDMLGLGNKETWRQMGEVFNLHLIAQEDVVNVPQRPKVVDYEDHLLIIAWMVMIKPNSSNFHKEQVSFILGKHYLLTVQEEADYDCFDPVRDRIRKGQGAIRKNKADYLAYTLLDSIIDGFFPVLEIYGEQIEELEDEVVAKPTRKTLEKIYKIRRDLLTLRRAIWPQRDAINSLIRDGSDLISPEVRIYLRDCYDHTVQVMDMVETYRELSSGLMDVYLSSMGNKMNEIMKLLTVMSSIFIPLTFVAGIYGMNFNTEKSPFNMPELNWYLGYPLCLGLMGAIASGLVYFFWRRGWFENFSTVKDDRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWN1</accession>
    <name>A0A2G4EWN1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000138">
        <property type="protein sequence ID" value="PHX53943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53943">
        <property type="protein sequence ID" value="PHX53943"/>
        <property type="gene ID" value="CP500_018795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10759" checksum="6FD2F3EF7B4A09D4" modified="2018-01-31" version="1">MLSQIFYLLRSRADGKYISACPNPDSTVSFLLIFREDYDALSYLNAHAADFADRFGVESISSPQIKKLLERWGFQGVGIVQDPLQPNIEFLLTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWP0</accession>
    <name>A0A2G4EWP0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000138">
        <property type="protein sequence ID" value="PHX53941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53941">
        <property type="protein sequence ID" value="PHX53941"/>
        <property type="gene ID" value="CP500_018785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="13438" checksum="2EA04E3E102753ED" modified="2018-01-31" version="1">MKIQSSVLVHLGFGKYVRSDRVTAVIPIEAERGPGRRTFVHIDGELDPIVASRAEDTIVRDLVQEPREITQARQQQEILQDLLTDLSNVNVTVRRISRDEGGLDLELLERRIRQILEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWT8</accession>
    <name>A0A2G4EWT8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SxtJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53989">
        <property type="protein sequence ID" value="PHX53989"/>
        <property type="gene ID" value="CP500_018625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045781">
        <property type="entry name" value="SxtJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19588">
        <property type="entry name" value="SxtJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="15437" checksum="330A53E4B480FDC2" modified="2018-01-31" version="1">MSDEIKKLDQKGLRDFGLLIGGLIAFLFGLVVPLLRRHPTHWLPWAIGAVLIVLALVAPKSLNPIYHGWMRFGLILNKIETPIILGIVFYLIIWPMGAIKNIFGEDAMRRKLNPKMDTYRVQSKARTKVSMERPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWZ9</accession>
    <name>A0A2G4EWZ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid oxidation protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000162">
        <property type="protein sequence ID" value="PHX53687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53687">
        <property type="protein sequence ID" value="PHX53687"/>
        <property type="gene ID" value="CP500_020140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="136" mass="15959" checksum="2001DFB024AAC695" modified="2018-01-31" version="1">MAKDRFHDVVKTALEKEDWQITADPYQINVDDVDFEIDLAAEQLLAAQRESQKIAVEIKSFISSSNVSDFHTALGQFLNYRDALETIEPDRLLYLAVRVPVYESFFQRRFIVAAVKRYQLRLMIYDVQQEVIVQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX40</accession>
    <name>A0A2G4EX40_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OstA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54091">
        <property type="protein sequence ID" value="PHX54091"/>
        <property type="gene ID" value="CP500_018015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005653">
        <property type="entry name" value="OstA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03968">
        <property type="entry name" value="LptD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013848278" evidence="1">
        <location>
            <begin position="26"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="OstA-like_N" evidence="2">
        <location>
            <begin position="70"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="16972" checksum="7E2B6960A179F063" modified="2018-01-31" version="1">MISSTKLLKSRIFKGLLLLLPLTLAGTLASPTYPQATVPRTLSVRSDIQEADSKTGIVTARGNVQINYPARQMQATAAQAQYFSRERRIILSGDVYVLQQGNSLRGETITYLIDEGRFIALPDKPGQVESVYLVAPEQDAAAQNTIGSPRPTTAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXB0</accession>
    <name>A0A2G4EXB0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000119">
        <property type="protein sequence ID" value="PHX54173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54173">
        <property type="protein sequence ID" value="PHX54173"/>
        <property type="gene ID" value="CP500_017580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="207" mass="22666" checksum="61DD2E8E5877B0FB" modified="2018-01-31" version="1">MRYGKFPGLYTKFCNPSSEEYTEFLRRHGNFYAIGSNCTVLPSTVFTDPAYVRIGNNVHFSSCTLIGHDGVIAMLNRAYNVKLDSVGKIDIRDNVFIGYGAIVLRNVTIGPNAIVAAGAVVVKDVAEGDIVAGVPARPIGRVEDLVKKLQAETESLPWVDLITSRKGSFDPEIESQLVQLRVSHFYGNTSTPTATRSVDLSQPTFHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXC4</accession>
    <name>A0A2G4EXC4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000117">
        <property type="protein sequence ID" value="PHX54179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54179">
        <property type="protein sequence ID" value="PHX54179"/>
        <property type="gene ID" value="CP500_017495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="59" mass="6683" checksum="CF571EB03A648869" modified="2018-01-31" version="1">MNRGAYDEDAELFSRSKSDIATAKAVNTFLIAETIDFIAFFLLPTSVFQLRFSLYSNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXP1</accession>
    <name>A0A2G4EXP1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53927">
        <property type="protein sequence ID" value="PHX53927"/>
        <property type="gene ID" value="CP500_018895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12529" checksum="9AFD7952B2DAC46E" modified="2018-01-31" version="1">MAKLAPETIATILNLQARLLAGIDQASSAEFAIFQQYGEIEATATVLEQLQNASERLRNPYSRFYTLLLRISESQPTASSAMLNLLAQTIEQAEADASAIEATIREAKRDFNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXP9</accession>
    <name>A0A2G4EXP9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphonate ABC transporter, permease protein PhnE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phnE</name>
        <name evidence="6" type="ORF">CP500_017140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54256">
        <property type="protein sequence ID" value="PHX54256"/>
        <property type="gene ID" value="CP500_017140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015416">
        <property type="term" value="F:ABC-type phosphonate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005769">
        <property type="entry name" value="PhnE/PtxC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01097">
        <property type="entry name" value="PhnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="264" mass="28873" checksum="6A9AFC3CA3C6DBD5" modified="2018-01-31" version="1">MTEKKSSNLSRNYGWIKNLGIATGLIVIYGWALQGLEIDAGTLASSWPYMTDFISRLWPPNLEIIDVAIKALIETIQMSLWGTTIGAIISVPIAICSAHNIAPKWLQWPANFIQNAVRSVPSIVLGLLFVSATGLGAPAGTLALGIYTIGYLAKFYQEAIESVEVRSIESLQVGGASWLQVAQYGIFPQVLPLVLGYTLWMFEYNIRAASVLGVVGAGGIGFELVNYIRAFEYNKATTMMLVLLVVVTVIDVISSKWRQRLEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXQ7</accession>
    <name>A0A2G4EXQ7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016755</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54324">
        <property type="protein sequence ID" value="PHX54324"/>
        <property type="gene ID" value="CP500_016755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010046">
        <property type="entry name" value="Mopterin_OxRdtse_a_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF4">
        <property type="entry name" value="PTHR43105:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01701">
        <property type="entry name" value="Fdhalpha-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin" evidence="3">
        <location>
            <begin position="122"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="4">
        <location>
            <begin position="650"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="757" mass="82966" checksum="B4CD7A9F0655E2BA" modified="2018-01-31" version="1">MDTKSQNVQPIPPFSDKNEETPEIGGGLPVIEFWAQHTLSPEGPKLWKTLLHKSACLSCSWGTGGQKGGFTNEEGEKLQRCMKSVEAISAEIKPAVSNHYFETHSIAQLQQLTSMECDRLGRLGFPMILRAGKSHYDHISWQEVYEIAADAFGKTPERVASYSSGRSSNEAAFLLQLMMRAIGSNNLADCSDLCHAPSTTGLREMFATGTSVVSLENLKQADCVVLTGSNAAYNHPRLMNELIKIREKGGKIIVINPMMEIGLIKFGSPAFPVKSLIPGSDISSLYLQPIPGSDTALFVGIQKSVIEQGLLDEKYLQSHTENWESVVQHARETTWETIIETCGVSRAEIEAAAKIIGNSKRVVFGWAMGITQQENGVDNVFSIANTALMTGNVGKEGAGLMPVRGHSNVQGFGSMGVTVNLKKEIQQAIEKLLGRSLSPVKGYETRSLIEAADAGQVDTLICLGGNLYGANPDSTQAKRALGKIETIIYLATKPNLGHFHGLAKHNTIVIPVLNRFENPHKTTVESGNNFVRLNDEGKTHLTDADLIPEVQFLTELASQIHGTYPVNWRNLQDTKYVRKLIALTIPGYEKIGNIDETKEEFTISGRIFAEPKFPTDSGKAKMFVAPLPTLKLPEPQEFGASESTRGIVVALMTGRSYSQHNTVVYKIDDKYRGMPHRNCILMNRVDAESAGLQEHQRVTVQGNVGKMANVEVIYGAVRVGAALMFYPEVNVIFNPRVEMRSGTPAYKRVPAFVYAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY19</accession>
    <name>A0A2G4EY19_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54419">
        <property type="protein sequence ID" value="PHX54419"/>
        <property type="gene ID" value="CP500_016175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="11512" checksum="9FDBCD2D714657A3" modified="2018-01-31" version="1">MAYSSENPIVQLKKCLTMAQDVSSHAEASRAFEQLCGIIDAENPMAAQLLEMLWQEAIMARRSALFWQQMSDVEKDMANKMMENMTQMRQNYLRLMQEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYC5</accession>
    <name>A0A2G4EYC5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54534">
        <property type="protein sequence ID" value="PHX54534"/>
        <property type="gene ID" value="CP500_015550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="21016" checksum="BC5E74FFDAC280F3" modified="2018-01-31" version="1">MSTTEKVRWTSADLESLPDNGNRYEIIEGELVVTRAPRWEHQDVANNVCVELTIWSRQTKLGKAVQVPGLIFTDADNVIPDVVWVSYERLAQILDQSGHLAGAPELVVEVMSPGEENEKRDRQSKLKLYSVQGVREYWICDRLQQKVEVYLRENGVLKLAMTLFKEDNLTSPLLPGFSVSVAALFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYE0</accession>
    <name>A0A2G4EYE0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_015790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54498">
        <property type="protein sequence ID" value="PHX54498"/>
        <property type="gene ID" value="CP500_015790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008318">
        <property type="term" value="F:protein prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018342">
        <property type="term" value="P:protein prenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="33"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="67"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="169"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="203"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="237"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="304"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="338"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="372"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="409"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="443"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="477"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="511"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="564" mass="64892" checksum="1EE08A3DDB28C581" modified="2018-01-31" version="1">MSDFSTSAPKTSNNNLSNPQSTLLPPFFRIFAAFRDYDRGNRLYASGRYEAAVDYYGRAVQTKPDWARAWLNLGKAYKQLGQYVETVACCDRAIALKPQEYWAWMLRGTALLDLQNYSEAMTGFDQAVLINSEKHEAWYQRGRALEELQQWDASASSYKRATELHPNLPAMWCRQGNVLLQAQRNAEAVAAYERAVKLVPTNWEAWLNRGLALMKTERYPEAVTSYDRAIQLQPTNCLAWFNRGIASAKLHRYVDAVRAYDRVIELQPNDYEAWFYKGMALKHQQRYAAIACFDKAIQINQLYPEVWIGRGQTLSESEEYEEAIAAFDKAIHINPNFPEAWLGRGIALAGLERYKDAIIAYSNALQIQGNFLEAWNLRGEALEQLQQYEEAIACYDKVISLSSEAKISSKVGLQQGAALEKLERYKEAVAAYNKVIKIMPDNFEAWLKRGNALEKMQQYEPSLLAYDRAITIWPDNYEAWMHRAILLAKMKRYAEAVIACDRVIQMKPNNWEAWAHRGDVLQKLERNQDAISSYGVALEIKPDYYEALMSREELRMKDTMPGKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYQ2</accession>
    <name>A0A2G4EYQ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54620">
        <property type="protein sequence ID" value="PHX54620"/>
        <property type="gene ID" value="CP500_015185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013639785" evidence="1">
        <location>
            <begin position="27"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="202" mass="22778" checksum="91C56ECA2F26E7E4" modified="2018-01-31" version="1">MKKVFNSLVGVTTILLAFFLVTPTQAQNTQYEVLIFARKPENSRIPLPNDAGHAWIAIIRNDGNGQWQTDATYGFWPESRNEPSVNQGTDFDHTNRYLRGQPLSRRGQAVRKAKIGTNRANWIKNGAYREAGCANYQAFGGTGTSCNCADYATRLWWVLTARQEDFRIRAVTLNLTLDSLVNEINSKNRATGDFLDSGRTWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYS9</accession>
    <name>A0A2G4EYS9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterodisulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54337">
        <property type="protein sequence ID" value="PHX54337"/>
        <property type="gene ID" value="CP500_016610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCG" evidence="1">
        <location>
            <begin position="8"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="CCG" evidence="1">
        <location>
            <begin position="158"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="301" mass="33203" checksum="8B641DCC82E16E68" modified="2018-01-31" version="1">MPSQNLKYAYFPGCVAQGAARELYLSTQALTQALGIELVELKKASCCGSGTFKEDSQLLEDTVNARNIALAEQLNLPLLTHCSTCQGVIGHVDDRLKDCQKTDRNYIDKVNGLLEKQGCSPYQGTTEVKHLLWAIVADYGLEEVQKRVTHKLSGLKCAAFYGCYLLRAQDKLLYDDPHQPESMENVFRAIGATPVYYRGRTQCCGWPLASYATNQSFQMAGKHIVDALDNGADCMVTPCPLCHLNLDSRQPEVEKVIGRKLGLPVLHLPQLVALALGVEPKKLGLDRHIVSTKPVLEKLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYT3</accession>
    <name>A0A2G4EYT3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase</fullName>
            <shortName evidence="3">SEPHCHC synthase</shortName>
            <ecNumber evidence="3">2.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menD</name>
        <name evidence="6" type="ORF">CP500_014930</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="ChEBI" id="CHEBI:58818"/>
            <dbReference type="EC" id="2.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="3">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; phylloquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 2/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPP enzyme family. MenD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.9" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54650">
        <property type="protein sequence ID" value="PHX54650"/>
        <property type="gene ID" value="CP500_014930"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00995"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070204">
        <property type="term" value="F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042372">
        <property type="term" value="P:phylloquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01659">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004433">
        <property type="entry name" value="MenaQ_synth_MenD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032264">
        <property type="entry name" value="MenD_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42916">
        <property type="entry name" value="PTHR42916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16582">
        <property type="entry name" value="TPP_enzyme_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004983">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00173">
        <property type="entry name" value="menD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="4">
        <location>
            <begin position="13"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M_2" evidence="5">
        <location>
            <begin position="226"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="623" mass="69104" checksum="CDB98D9D12D0C733" modified="2018-01-31" version="1">MIDFRNTNTLWSSILAETLQRLGLTTAVICPGSRSAPLTIAFAQNNQIETIPILDERSASFFALGIAKKSHLPTALICTSGTAAANFYPAIIEARESRIPLLIFTADRPPELRDCHAGQAIDQIKIYGNYPNWQVELAIPSAEIAMLGYLRQTIIYAWDRSQFPTPGPVHLNIPFRDPLIPISDIAVEALETQFNPEDFFAGLEPIFAGETSTPPSPPLLRGGEESTIQQWQKCSRGIIIAGVAQPQFPEKYCSAIAQMSKLLNWPVLAEGLSPLRNYAQLNPHLISTYDLILRNRELADKLTPEIAIQIGDLPTSKELRNWLDKTQPKRYIIDPSHHNFDPLHGKTIHLRTSPENLATAISLHVPPLSKGGLGGVQDRGNHGGIAPTDNETALGLGGVLTSPSNEYLQLWHNTETQVRQTIDQKLSAINNIIEPKISWLLSQNLPAGTPIFISNSMPVRDVEFFWKPNNLEIKPFFNRGANGIDGTLSTALGVAHRNQSSILLTGDLALLHDTNGFLIKHKFVGYLTIILINNNGGGIFEMLPVAKFDPPFEEFFATPQHINFAQLCATYSVEHEIINDWEQLKEKLSLPSNNGIRVLELQTDRRVDAKWRQNNLSKFAQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYW5</accession>
    <name>A0A2G4EYW5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">DNA repair protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">radA</name>
        <name evidence="9" type="ORF">CP500_014810</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54686">
        <property type="protein sequence ID" value="PHX54686"/>
        <property type="gene ID" value="CP500_014810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01121">
        <property type="entry name" value="Sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014774">
        <property type="entry name" value="KaiC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00416">
        <property type="entry name" value="sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RECA_2" evidence="8">
        <location>
            <begin position="82"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="157"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Lon-protease-like" evidence="5">
        <location>
            <begin position="398"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RadA KNRFG motif" evidence="5">
        <location>
            <begin position="299"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="111"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="522" mass="56265" checksum="3AD3EC11E299A4C3" modified="2018-01-31" version="1">MPKPRIQYICRECAYESPQYFGRCPSCQKWDSFDEQAEHSTIAAPRAGLTGVTTKGKGGAPPDKSKGQARVSFRLSQIADQTQSRWPSGYAEFDRVLGGGIVPGSLVLIGGEPGIGKSTLLLQVANKLARKDRILYVSAEESGQQVKLRSQRLGVANPVDLSSDSSDKSDSNGHTTNGATPIDPDDHSAENFYLLPETDLEVVLRELEALKPNVAVIDSIQTIYFASLTSAPGSVAQVRECTSALMQVAKRENITLFIVGHVTKDGGLAGPRVLEHLVDTVLYFEGDRFASHRLLRSMKNRFGATHEIGVFEMVAEGLREVDNPSELFLGNRDEFSPGTSTTVTCEGTRPILVEIQALVSPASFGSPRRSTTGVDNGRLQQILAVLEKRVGIPLSKLDTIVASVGGLKVEEPAGDLAVAIAVVASFRDRIVDARTVLLGEVGLGGQVRPVSQLELRLREAAKLGFKRAIIPKNQPVPELGMQIIPVAKVIDAIIAAIPATPTQLQSVDVVKMEEIEEIEDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ26</accession>
    <name>A0A2G4EZ26_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PD-(D/E)XK nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54447">
        <property type="protein sequence ID" value="PHX54447"/>
        <property type="gene ID" value="CP500_016070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="1">
        <location>
            <begin position="84"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="271" mass="31874" checksum="57B78C07743D3261" modified="2018-01-31" version="1">MFRLSQTQLKIIKECPRKFQHSYLELLATHSPPEHQAKLEWGSRFHLLMQQRELGLPIALIGQPDTEMQRCLVAFVNSAPELFTQSENDNKTFRQAEHVRTLIFQDYLFTVIYDLLIAEPNQAQILDWKTYPRPQKSQWIAQSWQTRLYLYVLVETSDYSPEQVSMTYWFVQLQGEEPPQSLTFTYNQIEHDRTKQDLTNLLHQLTDWRQRYSDKGEFLPQVDISANLCNSCQFATRCHRTQDTKASLANLAVETSTDWLPNIAIIDEIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZA3</accession>
    <name>A0A2G4EZA3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54842">
        <property type="protein sequence ID" value="PHX54842"/>
        <property type="gene ID" value="CP500_014030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="80" mass="8933" checksum="01A4303E8A198BED" modified="2018-01-31" version="1">MKTQTLDRPASSVPFTLNFVEKLDPALYDQAIQDSEMLKQSYDPETQTSNIAIYAGTSLTYSNTRCGLLPHDDDTKQSDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZC0</accession>
    <name>A0A2G4EZC0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfate ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_013850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic sulfate-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54860">
        <property type="protein sequence ID" value="PHX54860"/>
        <property type="gene ID" value="CP500_013850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901681">
        <property type="term" value="F:sulfur compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902358">
        <property type="term" value="P:sulfate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01005">
        <property type="entry name" value="PBP2_CysP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034408">
        <property type="entry name" value="Sulphate/thiosulphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005669">
        <property type="entry name" value="Thiosulph/SO4-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30368">
        <property type="entry name" value="PTHR30368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00971">
        <property type="entry name" value="3a0106s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00757">
        <property type="entry name" value="PROK_SULFATE_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="41094" checksum="EFDB346ACAEB5861" modified="2018-01-31" version="1">MRNHHLPDSALQPLKKKTGQPVFSLKSATLLKSSLFRFFTFFFAVGLGLSWVIPQPAISQPKPKDVELTLVSFAVTKSAYDKILPGFVAKWKRENNQNVKFNQSYGGSGSQTRAVIDGLEADVVHLALAYDTDRIQQAGLIKAGWEREVPNNGIVSKSVVALVARSGNPKKIQGWADLAKPGIKVITANPKTSGVARWNFLALWGSVTRNGGNEQAARSFVTQVYKNVPVLPKDAREASDVFYKQNQGDVLINYENEILLAKQKGETEPFIIPQVNISIDNPVAVVDKNAAKHGTTKVAEAFVKYLYTPEAQQEFAKVGFRPVNSTVAGQFSSQFPKIGKLFTVADVGGWKAVQNKFFADNAIFDQIENGLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZG2</accession>
    <name>A0A2G4EZG2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-acetylglucosamine-6-phosphate deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nagA</name>
        <name evidence="5" type="ORF">CP500_013560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="4">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54910">
        <property type="protein sequence ID" value="PHX54910"/>
        <property type="gene ID" value="CP500_013560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00854">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="PTHR11113:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00221">
        <property type="entry name" value="nagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="244"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="341"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR038994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="409" mass="44352" checksum="BD0B0874109BE61B" modified="2018-01-31" version="1">MTKATTPNLSPTNILNAKLPGFQDLQMLAVDESGIIQEVCPMNKVFKRVSSPDLPIFDAAGDWLSLGGVDLQINGALGLAFPDLESKHIEFLPKICEFLWNQGVDAFLPTLVTTSLDKFRRSLSTIAKFIRTTKTATSSTNQLKTAEIIGVHLEGPFLNPHKRGAHPSQFLLPLTIENVKLVLGDCADIVKIITLAPELDSTGEVISYLQSLGITVSLGHSQATAEQAEHAFARGASMVTHAFNAMPSLHHREPGLLGAAIVSSGVKCGLIADGRHVSPTMIDFLLRAGRYETGVFLVSDALAPLGLRDGVYPWDSRQIEVRKGTAWLRLDYHTALESATLAGTTLPLLAGVQNLVKWGICDVESAIALATDSPRKAIGLSGIIGKYATQLLRWHLNEPTKELTWHRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZH0</accession>
    <name>A0A2G4EZH0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54902">
        <property type="protein sequence ID" value="PHX54902"/>
        <property type="gene ID" value="CP500_013670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="123" mass="13481" checksum="C83579054E151BC0" modified="2018-01-31" version="1">MPTSDSYHDSKISNLKDPNYSAAYLSLIFDEEEEGDLEMGIMRQVLRDVFEALGEPIMSAEDAKLHLEKLDVLLPQSGIATIYALANWLKVLGLKLSVAVAQEDEGEEKGSVSAVELVEVAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZL6</accession>
    <name>A0A2G4EZL6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Keto-deoxy-phosphogluconate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.14</ecNumber>
            <ecNumber evidence="2">4.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.14" evidence="2"/>
    <dbReference type="EC" id="4.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54951">
        <property type="protein sequence ID" value="PHX54951"/>
        <property type="gene ID" value="CP500_013435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008675">
        <property type="term" value="F:2-dehydro-3-deoxy-phosphogluconate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008700">
        <property type="term" value="F:4-hydroxy-2-oxoglutarate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01182">
        <property type="entry name" value="eda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="218" mass="23055" checksum="885CF5D990120781" modified="2018-01-31" version="1">MNHQAWLTSLKKHRAIAVIRSSDKEIAWQMAKAVAKGGIQFIEITWNTEKAAELISQLRLELPTFSIGTGTLLNLEQLQEAIDCGAQFLFTPHADVAMIKVAVDAGVPIVPGAFSPTEIVTAWQAGATCVKVFPISGLGGAAYLKALQGPLGEIPLIPTGGVTLDSVKLFIDAGAIAVGLAGDLFPKHLVANGDWEAIAQIARTLTQNLTTSESSFPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F070</accession>
    <name>A0A2G4F070_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55146">
        <property type="protein sequence ID" value="PHX55146"/>
        <property type="gene ID" value="CP500_012235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="275" mass="30205" checksum="B7695A5ADF123A38" modified="2018-01-31" version="1">MGVRETQLKLESAKVQQLYRKMQADQKALQQQLKEFKTQTGNFSDLVEQVLPSVVSVYVMDWDTGEEISSGSGFFVAPDTIVTNYHVVEDIADEDYFYEEDEVEQVLVETNDGKLRMAEVIFTGNAEEDLALLLITGFVIDPKTGEQVESPEEYPPLELSSDVKVGDRVIAVGNPLGQFATTVTQGIVTAIREPDEYEEGEDDEDDVAGVKMLETDAVINPGNSGGPLINMAGQVVGVNMWGWEDADSLNLAIAAIALDDFLAGFEETFEDDSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0B6</accession>
    <name>A0A2G4F0B6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_012090</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55193">
        <property type="protein sequence ID" value="PHX55193"/>
        <property type="gene ID" value="CP500_012090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="8">
        <location>
            <begin position="37"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="271" mass="31382" checksum="1C8669D1DB7A8115" modified="2018-01-31" version="1">MTIATQDKLQYNWTHIIALAGVHIGALFAILPSNFNWTAVGLTVFMHWITGGLGITLGWHRLLTHRSFQTPKIVEYFLAFCGALACQGGVIHWVGLHRLHHTHSDQNDIDPHNAQQGFWWSHMGWMLYKGPAHDEIPRCTKDISSDPFYQFLQNYFLPIQIAFGILLYLAAGWPFVVWVIFVRLVVVYHCTWFVNSATHKFGYRTYETKDSSTNCWWVAVLTYGEGWHNNHHAYQYSARHGMEWWEIDFTWMTIQVMEALGLASKVKLPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0B8</accession>
    <name>A0A2G4F0B8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_012075</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55200">
        <property type="protein sequence ID" value="PHX55200"/>
        <property type="gene ID" value="CP500_012075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="76"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="277" mass="30166" checksum="F30FDC060F18C2E5" modified="2018-01-31" version="1">MENPQEEIPADMYLKPKFKISWQVVFAILMFFYMYLPILVLTFYSFNKSRFSAGWEGFTLDWYVKLFSDTRILVALRNSLTVAVCAVAISAVLGTLMAVGLSRYRFPGKSLYQGVAYLPIIIPDIASAVATLVFLAALAIPLSLWTIVAAHIVFCLAYIALAVSTRLADLNPSLEEAALDLGATPVEAFIQVLLPQLLPGIVSGCLLAFVLSMDDFLIASFTAGSGTTTLPMEIFSRIRTGVKPDINALSVLLMVGSGGLAFAAEYLRGRSDQKRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0I7</accession>
    <name>A0A2G4F0I7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">HlyC/CorC family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_011505</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55266">
        <property type="protein sequence ID" value="PHX55266"/>
        <property type="gene ID" value="CP500_011505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="219"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="283"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX55266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="443" mass="48540" checksum="5A0E9EA34D76B662" modified="2018-01-31" version="1">MSPSTDFLIVLLLIFLNGLFVMSEMAIISVRKVRLQQMANQGSINARVALDLANAPNQFLPTVQIGITLLAILSGAFGETTLAKRVEPLLHLIPALAPYSKTIASVVAILIITYLTLIIGELVPKRLALNNPEPIASSVAIPIRMLSKIGAPAVYVLSYSTDLVMRIMGILPSTEPQVTEEEIKVLIEQGTEAGTFEEAEQDMVERVFRLGDRRVSALMTPRPDLVWLDLDDSVEENRQKMLDSGHSRFPVCQGGLDNVVGLVHVTDMLSRTLTGQPLDLSASLRRPLFVPESTRGLKVLELFKQSSNQLALVVDEYGVIQGLVSVNDILVELVGDFPSIQDADDPQSVQREDGSWLLDGMLPVEDFFELFGIEESSAENKGSYHTMGGFVITNLGKIPAAAEHFEWNGLRVEVVDMDGNRVDKILVMPIDSAANLPTSNRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0M6</accession>
    <name>A0A2G4F0M6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55319">
        <property type="protein sequence ID" value="PHX55319"/>
        <property type="gene ID" value="CP500_011485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="9148" checksum="0709762220AF1C26" modified="2018-01-31" version="1">MVKMRSPIHKKPDRPSIQKCDRGAPETGFLRQFFVTTHRFGQKPGFFAGRRGPRNRVFMTIFRYSDRFGQKPGFLDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0U1</accession>
    <name>A0A2G4F0U1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tatA</name>
        <name evidence="9" type="ORF">CP500_011280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Forms a complex with TatC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TatA/E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55373">
        <property type="protein sequence ID" value="PHX55373"/>
        <property type="gene ID" value="CP500_011280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="87" mass="9486" checksum="FFA16DAA0296D0BA" modified="2018-01-31" version="1">MNIFGIGLPEMAVIFTIALLVFGPKKLPEIGRSVGKALRGFQDASRDFESEFNREAKQLEETVATTKSKPETEKLAAATPKEDTADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0U9</accession>
    <name>A0A2G4F0U9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55375">
        <property type="protein sequence ID" value="PHX55375"/>
        <property type="gene ID" value="CP500_011140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="9163" checksum="CFCEBCAA0CD495D8" modified="2018-01-31" version="1">MVTGVPPTAGVGVGVGVGVGVGVGVGVGVGVGVGIPGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVGVVGVANAKFRVYWLLLFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0V8</accession>
    <name>A0A2G4F0V8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55385">
        <property type="protein sequence ID" value="PHX55385"/>
        <property type="gene ID" value="CP500_010955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="213" mass="22862" checksum="45542A9B14AB07AD" modified="2018-01-31" version="1">MTKRQHQNLSHSRDGGYTIIESLVAMIVVSVLMIAIAPVMAYSVATRVQARRIELATQAARTYIDALRVGAIRPNDATSPVGFPAKDVATIPAAPTNSNGLYCFDLDETAGCAGSKEFFVQGAWRNPANTTTDPTTTGYDLTVRVYRADGFTGKLMTITEQSVANFPLGNPQAPLMVMQTQIPPTTQGGSSAYRSLCQGIRLNGVVDQTKCTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F152</accession>
    <name>A0A2G4F152_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55491">
        <property type="protein sequence ID" value="PHX55491"/>
        <property type="gene ID" value="CP500_010310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="6600" checksum="784958F79EBE7CA6" modified="2018-01-31" version="1">MSQGGILSAIKYQVHVEQAVDTLKADLPTLFEKDIYTVEPYSAQKVHIIESVLSCSSSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F179</accession>
    <name>A0A2G4F179_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55521">
        <property type="protein sequence ID" value="PHX55521"/>
        <property type="gene ID" value="CP500_010465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="15416" checksum="03A384901B3731E3" modified="2018-01-31" version="1">MNSQFNNSANHSQVGIKPEQLDEIISAILSGKYSWACFLLLRCTGYNPLDYIPYRTSNRLLKENSQISQSNKSETKSALGKIADLDYVEVARDKRAGVRGGFVPEVNGEAEYLSSPTVDVQNQGFFAGFKTRLFNLAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1H5</accession>
    <name>A0A2G4F1H5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rubredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_009975</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the rubredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55595">
        <property type="protein sequence ID" value="PHX55595"/>
        <property type="gene ID" value="CP500_009975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018527">
        <property type="entry name" value="Rubredoxin_Fe_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00301">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00163">
        <property type="entry name" value="RUBREDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00202">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin-like" evidence="7">
        <location>
            <begin position="11"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="12007" checksum="8A2B981536A9A29A" modified="2018-01-31" version="1">MSDRATETTTLDRHECRACGYVYNPKKGDPKNAIAPGTAFTDVTPTWVCPVCGARKSMFQNLGQMEGASGFKANQRYGVGVNSMTEGQKSLLIFGGLVVGFLFLLSMYGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1I0</accession>
    <name>A0A2G4F1I0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55620">
        <property type="protein sequence ID" value="PHX55620"/>
        <property type="gene ID" value="CP500_009825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10787" checksum="E34FEC0604520DE8" modified="2018-01-31" version="1">MATLQIENIPEELYARLQELADAQNRSISAFAIAILEAELSTKTKPLSGQRKKSVRELLAEISRRRESRPANMGMILDSTALIREDRDKNITRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1I8</accession>
    <name>A0A2G4F1I8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_009775</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55612">
        <property type="protein sequence ID" value="PHX55612"/>
        <property type="gene ID" value="CP500_009775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="205"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="262"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="340"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="432"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="383"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX55612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="692" mass="77767" checksum="036CCD4CBF771FAD" modified="2018-01-31" version="1">MKLFPFPLRFSIPVILMIFGSLLGLFSFQREVEQSYRRQEEQGISNLKFSANQSSGMLEYLYRRGDVEEVEIAISKLGSDRNIRLALLCNENDTIIFATRYELRNQPVSNISLPHYLLAEFSQIREIMSGEVKLAENRESTWAIYPVLLGAKPGEVRPSRVGILLIEYDILLIKQQAYADALYRSTETSIGLALFCVIVWLFFHKTLTGRAARLVAVSNNFSKGKLDDRAQLGGSDELAQIAAAFNEMAERIQSHTEALQESEKRFRTLVSNIPGAVYRLVFDSDWKIQFISDGIAEISGYPAANFINTPVGVFQSIIHPKDAAMVEKTIKKSMVKKRNYTIEYRIIRPDKSVRWVSDKGQGIFNENGDILWLDGVIIDSTKRKRAEAELHQTLQLKDELAATATAQAKQLEQALQLIQTEKMSSLAQMIAGVAHEINNPVNFIHGNIDYVNKYSQDLLTLTDLYQQEYPNPHLKIAELIEDCELDFIKKDLPKILSSMKVGTDRIREIVLSLRKFAHLDESDVKFVNIHEGIDTTLLILQSNIKAKPYLEGIKIIKNYGCLPPVECYAGQLNQVFMNILSNAIYALHITKKQNSSKQQTNSSSQIIITTSIQEPDWVKISIKDNGPGIDDAVKPRIFDPFFTTKPVGTGTGLGLSISYQIVVDKHGGKLQCISAVGEGTELVIEIPIARTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1J4</accession>
    <name>A0A2G4F1J4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pruA</name>
        <name evidence="7" type="ORF">CP500_009815</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55619">
        <property type="protein sequence ID" value="PHX55619"/>
        <property type="gene ID" value="CP500_009815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:1-pyrroline-5-carboxylate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07124">
        <property type="entry name" value="ALDH_PutA-P5CDH-RocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025703">
        <property type="entry name" value="Bifunct_PutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041514">
        <property type="entry name" value="PutA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005932">
        <property type="entry name" value="RocA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18083">
        <property type="entry name" value="PutA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000197">
        <property type="entry name" value="Bifunct_PutA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01237">
        <property type="entry name" value="D1pyr5carbox2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PutA_N" evidence="6">
        <location>
            <begin position="11"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Pro_dh" evidence="5">
        <location>
            <begin position="137"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="515"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="750"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000197-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="990" mass="109823" checksum="4ADCABC4407BAD5A" modified="2018-01-31" version="1">MIAQVSPSIYEAKTQEIAKEILKATQDKKRSFFGQLQDQMRWDDKLLDWAMASPGLRVQLFRFIDCLPALRSKPEIARHLQEYLTAEEVELPEALKKLLNFTNADSIPGQLAATTVAPAVETLAHKYISGENIKQVVKTLERLRKDKMGFTVDLLGEAVITETEAQNYLDRYLELMQELSIAAKNWSQVDAIDKADGETLPRVQVSVKLTAFYSQFDPLDAKGSEAKVSDRIRFLLRRAQELGAAVHFDMEQYVYKGLTLSILKDLLLEDEFRDRTDVGITLQAYLRDSKQDLQGIIAWAKLRGNPLTVRVVKGAYWDQETIKAMQKDWPQPVYNDKVATDANFEEMTQLLLENHEYLYAAIASHNVRSQARAIAIAETLNIPRRRFEMQVLYGMGDKLAKLLVDRGYRVRVYCPYGDLLPGMAYLIRRLLENTANSSFIRQSSEEMPIEQLLAAPVANGNDQLVYTKVFPNVADTDYANTELRKQAETAIKSVRGILGQTYLPLINGEYQNTEASVNSLNPCNPKEVVGKIGLLSESQAKQALQAAKDASLGWRKTPVRQRAGVLRKAAELMEQRRHELSAWMVFEVGKPVRECDAEVSEAIDFCRYYADEMERLEQGQNYDIAGENNRYSYQPRGISLIISPWNFPLAIPVGMTVASLVAGNCTLLKPAEFSSVIAAKITEILVDAGIPKGVFQYVPCKGSTVGAYMVKHPDVHMITFTGSQEVGCKIYADAAILQPGQKHLKRVIAEMGGKNGIIVDESADLDQAVAGVVYSAFGYSGQKCSACSRVIVVESVYDVFVERLVEATRSLNVGIAENPGTQVGPVIDITAQSRIREYIEKGRAEAKIALEMSAPEIGYFVGPVIVTEVSPTATLAQEEIFGPVLSVIRAKNFNEAIAIANDTNFALTGGLYSRTPSHIDRAKADFEVGNLYINRGTTGAVVSRQPFGGFKLSGVGSKAGGPDYLLQFLEPRTITENIQRQGFAPIEGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1R3</accession>
    <name>A0A2G4F1R3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inositol monophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55703">
        <property type="protein sequence ID" value="PHX55703"/>
        <property type="gene ID" value="CP500_009410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="278" mass="30482" checksum="90A5D48FACE6E9EA" modified="2018-01-31" version="1">MKDFWDSILSFSQTTVKTVGQQFLKDFGSAQANEKDDGTLVTQSDNWADATIRSAIASTFPSHGILSEEGEHVFPDTEWCWVVDPLDATTNFARGIPIWGISLGLLYRGTPVFGCVHLPPLNQTFHGFFAGDFLEKNVLTDIPQGAFLNGKLIRPTADKMSGNHIFNLCSRSVGIGPHLPSKIRMLGMASYNFLTVASGVSMGGVEATPKIWDIAGSWVIVKAAGAVWLPLDSQAIFPLEVGKNYARISYPTLVMNRQELVSVFLPFVEAWKQKKLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F265</accession>
    <name>A0A2G4F265_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55839">
        <property type="protein sequence ID" value="PHX55839"/>
        <property type="gene ID" value="CP500_008795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="21090" checksum="C5C57020663A4899" modified="2018-01-31" version="1">MRLVICPGIHDRKLTDCFLAGLSEVWGNVEPWQNTQTFQSVKIFPAHKHPPFSALDIFHFLCSQELAGESLVFVSFSAGVVGAIGAALLWQQMGGKVGAFIALDGWGVPLGGNFPIHRLSHDRFTHWSSAILGSGGDSFYADRPVAHLDLWRSPQTAQGWQISHTADGIETAKSATAATFLVHLLKHYGVQSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F280</accession>
    <name>A0A2G4F280_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55883">
        <property type="protein sequence ID" value="PHX55883"/>
        <property type="gene ID" value="CP500_008280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="179" mass="20008" checksum="A4AA3844EF66BEE7" modified="2018-01-31" version="1">MDVQEVLKNLDELILSQTGKQLDTLQVAILKGVLKGQKYKDIAEEYNCTPGHVKDEAYELWRTLSNALGEDVNRANVRASIEKIIIKNPRNFKSPNSFNITFCPNSIPNSKFYSPEDLELIGGKLTKKSSSANWESIIKNARKKAKLEAVPYLAKMELTAAQIAEALDLPLAEVQELMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F286</accession>
    <name>A0A2G4F286_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Twitching motility protein PilT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55884">
        <property type="protein sequence ID" value="PHX55884"/>
        <property type="gene ID" value="CP500_008285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09872">
        <property type="entry name" value="PIN_Sll0205-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041705">
        <property type="entry name" value="PIN_Sll0205"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="136" mass="15426" checksum="C8CBB8FCB5E72EE7" modified="2018-01-31" version="1">MGISYLIDTHILLWWLFDDPKLNAQCRDIIRNPDFNIIVSTVSAWEIATKYRIGKLPEAKQIVGEYSQILHRSQFIELAITSAHALRAGSLPIPHRDPFDRMIMAQAELENLPVITYDTAFHTGLIEVIPAAESRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2A9</accession>
    <name>A0A2G4F2A9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_010035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55607">
        <property type="protein sequence ID" value="PHX55607"/>
        <property type="gene ID" value="CP500_010035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="11"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="400"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="434"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="468"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="502"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="570"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="709"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="743"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="786"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="820"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="682"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="873" mass="97592" checksum="ABE58C1CFDAA15EB" modified="2018-01-31" version="1">MKENETLMGRYKILEHLKSGGFTETYLAKDDLLPGNPQCVIKQLKPRSLDPLTLQAARNLFDTEARVLDILGHHDQIPSLLAYFEENEEFYLIEEFIDGESLDQEQAQGQRLSEPQVIALLQDVLEVLKFIHQSNVIHRDIKPSNIIRRKDGKVVLTGFGSVKQVNTQVVTGEGETSFTVPVGTNGYMPNEQQGGKPRFSSDIYALGMTAIHALCGTPPSKLQEDPQTGEVIWRYQTQIGDRLATILDKMVKSHYRDRYQTVDEVIHDLQNLTTPEIEVPPDSEFTSGSSVVTSGLNWQKIRKPVSIVALVALVAIIGSIVAYLNLNKNSTVFVQPLPTSTATPTATPTSTPEPTPTTAAEFVERGYKRLDPESAAEYKEALADFEEALKLNSNLPEALSGKNTAEGWLLLNEQKYQEALAKFDKAAEIKPDAANAWVAKGDALMNLQKYPEALTAYEKATQVKPDYYLGWFGQGIALAALQKYKEAIVAYDKALELTSDNSFIWNTRGDALRSLEQYTEAIASYDRAIKINETYLDPLVGKASALFLSGKRQEGLAAIDKAVKIDDNSAYAWIARGELLNSDGGHEGALASFERAIKIDAKNYLAWRGKSNALLKLRRLPEAIVAADEAIKFTPNYPLEQAASWNTKAIALYESRQLQEAKIAHEKVVQLNPNGEVGWSNLSELLNLLKEYDKALEAAEKALKIKQTIGGWNQQANALFGLKQYLKAIAAYDQVLKLKPDYHYAWVGKGNAYYELGQYKDAVAAYDKALEIQPKDRPLQEQSDKYATWNYKGKALLAEKRYEDALNAFDKAIEIKADFADGWFNKGRTHYELKQYKESLDAYNKVLEIKPDYAEAKVKREEVLQLQKVGQPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2B8</accession>
    <name>A0A2G4F2B8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55885">
        <property type="protein sequence ID" value="PHX55885"/>
        <property type="gene ID" value="CP500_008290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7795" checksum="9A0A84DDA0EB0FD2" modified="2018-01-31" version="1">MLIEKIVQELQDIPEDKLAEIYDLIHYFRLGLGREQPQPRTPGLLTGKLDDAFFEPLPEEELEQWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2G2</accession>
    <name>A0A2G4F2G2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YbjN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55657">
        <property type="protein sequence ID" value="PHX55657"/>
        <property type="gene ID" value="CP500_009610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019660">
        <property type="entry name" value="Put_sensory_transdc_reg_YbjN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10722">
        <property type="entry name" value="YbjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="167" mass="18203" checksum="53541A58244A90D8" modified="2018-01-31" version="1">MTTSEPNQETVSTENLLSESAIADAQVETATAVTYAEEIETVIASMAVDQKVMVGQNEAGGHLWKFKYGSVEVLVQLTGEMEDDTLTVWAFVLQLPAKNEAQLMRKLLEMNWLSTLESHFAIVDSQVAVLSTRTIAEISAGEISRAITIVATIADDHDDLLQAEFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2N2</accession>
    <name>A0A2G4F2N2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">OrfB_Zn_ribbon domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_009490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55717">
        <property type="protein sequence ID" value="PHX55717"/>
        <property type="gene ID" value="CP500_009490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="79"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="159" mass="18489" checksum="E194B1822FBA3232" modified="2018-01-31" version="1">MGRVSKASRKQKRRMLEAASKLRIRIRDLVDECHKQVVNYLTSEYKVILLPTFETSQMVVRSKRKLRTKTARQMLTWGHYRFECHLKQSAKKRGVVVIDVNESYTSKTCTKCGHKHSKLGGSKTFKCPNCGHEHDRDWGGARNIMIRALRDGYESSLYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2T4</accession>
    <name>A0A2G4F2T4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phycocyanobilin lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56059">
        <property type="protein sequence ID" value="PHX56059"/>
        <property type="gene ID" value="CP500_007450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03130">
        <property type="entry name" value="HEAT_PBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="277" mass="30144" checksum="7CB1849E85DF3643" modified="2018-01-31" version="1">MNYDESDSPPIANVDGESLTLEQAIANLHSQDYSLRYYAAWWVGRFRVKEPAVIAALIDALQAESEQTKIGDYSLLRNAARALGKLGDKQALPALIHCLQCADYYVREAAAQALEMLGDRNSIPPLMQLLDGGISTAVRVPGKSHLVQPYDSVIEALGTLKAVEAIPLIAPFLEHSVARVQYAAARAMYQLTGEVVYGELLVTALNGDNLQLRRSALMDLGAIGYLPGAQAISETLAENSMKLIALKGILEHHLEQQESLSVSDEAIRVMDLMDSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2V8</accession>
    <name>A0A2G4F2V8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56101">
        <property type="protein sequence ID" value="PHX56101"/>
        <property type="gene ID" value="CP500_007285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="36"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="260" mass="30402" checksum="3A3EFBD7AF1A406A" modified="2018-01-31" version="1">MVQQLTPETKPEIIYPDSDGEPMSDNTKQFRWIVTIKENLEILFANILDVFVAGDLLWYPVQGNNKIRQAPDAMVVFGRPKGDRGSYEQWKEDNIPPQVAFEILSPGNRPGKMAAKLLFYQRYGVQEYYIYDPDNIELSGFVRDEDWFEPIAEMNGWVSPLLEIRFQLTENTLEIYRPDGRKFLTPVEMDQLREQERQEKELAQSQAQQERQEKELAQSQAERERQRADEAIAQLELERQRYQALLQQINQQSIDSGPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2W7</accession>
    <name>A0A2G4F2W7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_007200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56085">
        <property type="protein sequence ID" value="PHX56085"/>
        <property type="gene ID" value="CP500_007200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="168"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="560"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="740"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1111" mass="127253" checksum="EF8145859FE35FCE" modified="2018-01-31" version="1">MIDVGSLVRSPKNDLGVGKVVEFSRTEALIEYFCSVKNRLSKTVPLALLQEARLQRQTRCYLWSTTQERWIIGRIYDWDEDRMLYDIDLPDSQSIQADETEIYVRCNIPIADPIDILAVKGQETPYFHDRRLAFVQSAIAQRAVSRGMTGLISANIDLYPHQVEVVRRVLEDPIGRYLLADEVGLGKTVEAGTILRQYLLDEPSGRAVVLVPKYLLEQWRDELENKFYLSHFADRVQLVSLSEINQISRNANLDFLIVDEAHHVAAMANSGDRSQKQCFEICQTLAHKSKNLLLLSGMPVLGHERDFLTMLHLLDPTTYRIDDLANFKEQVQNRQEIGHVLLDFRSGAKPVVLKPKLAEIRTLFATDDYLIGLADELDSCLETEKATECDRIIRTIRTHISDTYRLYRRMLRNQRDAVEDVIFDRDAIPKVEYDLNDEQWSEIHTILEKWRTLAPQKTAYQRIFLLFFRTSGTWLNVLERIVKARLQKKSTAELDREFGSKYMGIVTQTALFSGESAILESLLNAVEKPQEGADRLSLLRIAVIRFLGVTLKIPPEYHNKPRDLLSRIQQQIKRPLPGDKFPKIVIFTSFTGTCQAIAENLVKILGKNAIASHETSKSAADAEANLKRFKNEQNCFVLVCDRSAEEGLNLQFADWFIHFDLPWFPNQLEQRLGRVDRIGSKMGLQFCLFAGPDLPDSPHEAWYQVLKDGFGIFNKSIASLQFYVEQKLPQLEEKLFAEGAKGLAIEIQSIKAEIEQEKIKIKEQQVLDEIDLLDETASQYFESLDDCDAKHKEMQRATEGWICQALNFKQVEHPTISGLMRYQPSQKTLIPSNDLRTRLIPYCQQYGSYNRRVAHQNSDVALYRIGEGLIDALGSYIRWDDRGQAFALWRHDESWDAEEGKEWFGLQFNYSIQTDLQPAEQVLQSQNIENYNLKALQRRADALFVPVFETVFVDARNESMLLVEDGELLKILQRAYKGKGGPNRDYNLSKNRTVILDNFVDPLEWDDFCQRGRVVSEELLRGRGDFVEMCDRSAVSAAIQLENRVNQLQLRLNRLSQSEQLLESVLADEISTESVLSQAVLAGIRQPRLTLESVGFIVISGRAPVKSEDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2X2</accession>
    <name>A0A2G4F2X2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsH</name>
        <name evidence="8" type="ORF">CP500_006970</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cellular thylakoid membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Stromal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56124">
        <property type="protein sequence ID" value="PHX56124"/>
        <property type="gene ID" value="CP500_006970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="200"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="208"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="509"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="622" mass="67202" checksum="8CF64E1DB1E9A7C5" modified="2018-01-31" version="1">MAIKDQPQPPRFRQISNILLLLSSLFLLANIFLPNLFGPQIPQVPYSLFVHQVQEQNVVRASVGQNEIRYQLKGEGDQPGQVLSTTPIFDLELPKLLQEKGVEFAATPPSKNGWIGSVLSWVVPPLIFVAIFQFFMNRGGGGPQGALSIGKSKAKVYVEGESAKVTFADVAGVEEAKTELVEVVEFLKTPDRFTAIGARIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSEFVELFVGVGSARVRDLFEQAKKQAPCIIFIDELDAIGKSRSTNAAFGGNDEREQTLNQLLTEMDGFAAGNTTVIVLAATNRPESLDAALLRPGRFDRQVLVDRPDLSGREAILNIHSQKVKLGPDIDLKAIATRTPGFSGADLANLVNEAALLAARNKRLTVAQEDFYEAFERVVAGLEKKSRVLNEKEKKIVAYHEVGHAMVGALMTGGGEVAKISIVPRGMAALGYTLQLPTEDRFLLDESELRGQIATLLGGRSAEEVVFGSITTGASNDLQRATDLAERMVTTYGMSKVLGPLAYDRGQQAMFLNDGMGNARRAVSAQTAEAIDQEVKEIVETAHQQALDILKANRELLETITQKLLETEVVEGEALHKLLAEVRPLDQSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F350</accession>
    <name>A0A2G4F350_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56179">
        <property type="protein sequence ID" value="PHX56179"/>
        <property type="gene ID" value="CP500_006630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="8709" checksum="936A9BB09F968D61" modified="2018-01-31" version="1" fragment="single">GILPFLNGQDAHSTKKFTLCGTGILPFLNGQDAHSTKKFTFCGTGILPVADMAQDAHSTKKFTFCGTGILPVADMAQDVSYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F399</accession>
    <name>A0A2G4F399_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CP500_006420</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56240">
        <property type="protein sequence ID" value="PHX56240"/>
        <property type="gene ID" value="CP500_006420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="15" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="18"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="103"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="170"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="242"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="PHYTOCHROME_2" evidence="9">
        <location>
            <begin position="359"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="526"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="13">
        <location>
            <begin position="599"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="652"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="13">
        <location>
            <begin position="725"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="796"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="13">
        <location>
            <begin position="885"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="941"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="13">
        <location>
            <begin position="1013"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="13">
        <location>
            <begin position="1145"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="1197"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="13">
        <location>
            <begin position="1271"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="domain" description="PHYTOCHROME_2" evidence="9">
        <location>
            <begin position="1343"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="domain" description="PHYTOCHROME_2" evidence="9">
        <location>
            <begin position="1532"/>
            <end position="1683"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="1738"/>
            <end position="1974"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="2026"/>
            <end position="2142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1985"/>
            <end position="2022"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="761"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="921"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1690"/>
            <end position="1728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="2002"/>
            <end position="2020"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="2075"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX56240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="2149" mass="243702" checksum="D5C15DE62C4B1DDC" modified="2018-01-31" version="1">MFSRTTALTPTEQLRAAIVREPLVVSPDTTVIETIAQMSGVRSHCNTTRTADSQRDHLHLEARSSCVLVVENEQLVGVLTERDIVRLSAQQQPLHRLAMWEVMAHPVITLRQSAFTDLFFAINLLQQHHIRHLPILDEHDRLVGLVTHESLRQTSRPIDLLRLRLVSEVMTREVICAAPDCSLLAIAQLMAEHRVSSVMIVHPGRISTLMLQIPVGIVTERDIVQFQALGLNLETCLAEAVMSTPIFQVKPEESLWTVQQIMEQRSMRRLAVTGELGELLGIVTQTSLLQALNPLELYKLAQKWEEKVVCLEAEKVALLENRNLELERQVAERTLILKAKAHREQLLNTIAEQIRSSLNISDILDTTVQEIRSLLECDRVIIYEFRPDFSGTVIAEAITGTGRSVIHSEAHDPCISPEWLEPYRQGRIRIVNDIYGEAMTLCHQELLVGFDIRAKLMVPIVIEEQLWGLMLTSYRERPHLWTTDEIELVRQVSLQVAIALGQAMIHQKLQHELIKRQRIEATLIKSEERYAALAAAAPVGIFRTDTEGRCTYVNDRYFQISRLTPGATIGDAWQQRLHPDDRDWVIAQWGQFIQGNDSFELEYRFQRPDGEVTWVYGQCVPELDANGHRIGSIGTVTDISDRKRTEVRLQESEERYATLVEVSPVGIFRTDPGGNCIYVNDRWCQISGLTPKAAIGEGWRQGLHPEDRDSIALEWQQSAQQNRPFRLEYRFQRPDGAVAWVYGQSVAELDADGQVVGYVGAITDISDRKQAEQKLQQLNQELEAKVAERTQELWQVNSLQRAILNGADYSIISTDPTGIIQTFNAAAERMLGYDAQEIIGKVTPALIHDPNEVIEQAAILSAELKQEIPPGFEVFVAKARLGLISETEWTYIRKDGSRFPVSLSITALKDVNQQIIGFLGIAKDISDRKQAELERQQLIQELSAFKQALDQSAIVVITDPKGVITYANDRFCVVSGYSRNQLIGQTHRIVNSGYHPPSFFQNLWRTISGGQVWRGEICNRSKNGSLYWVASTIVPFLDEQGIPFQYLAIRFDITDRKLAEATLQHENTFRQQIVENMTEGLCVFYEVDEFPFLCFTVWNQQMQVITGYTLEEINRLGWYQSLYPDRWDQEWAIANLRQMQQGEYLAQEREIQRQDGIKRTIALSASILSSNDGLIYILALIQDITDRKQMEAQLAESEGKFRRLVEGGKDVIWSSDKDGIITYLSPQFKNVFGWEDSEWIGKPFIDLVHPDDLLFVHNDYEQNVNLSQKSSNSEFRHHHNNGNYIWVRTTITAIRNAEGVVISIQGVLSDITDRKEAEQIIQQQAERETLLREITQRIRQSLDLNTIFETATQEIRRFIQADRVGIFRFDPESGFDDGEFVSESVAPGFMSVLEIRVHDHCLGEQLSELYQQGRIQATNDIENTNLSDCHQAILSQFQVRANLILPLISGENLWGLLCIHQCSSPRQWQPKEINFTQEIANQLAIALQQANLYEQVQSELAIRKQTEKAIALQLKRQRTLGEITQQIRESLDIKQILATVTQQVKEILQGDRAIVFRLFVDGITQIVEESVFSDFQKLKNRHWENEVWSQEILEHYWQGKPRIVPDVMNDIWTDCLIEYSIEGQIQSKIVAPIVQEVRDSENHIWVAPEKTNKLWGLLVVHACREKRVWQESEAQLLQQIANQLAIAVQQASLFEQLQQQLTERQQAQQQLTERNQQLGASNEELARATRLKDEFLANMSHELRTPLNAIMGMSEGLQEQVFGIVNEKQIKALQTIERSGSHLLELINDILDVAKIESGQIELDCAPVSINHLCQSSLPFIKQQALQKRIQLEIKVPLNLPDLLIDERRMRQVLINLLNNAVKFTPNGGRITLEVSRQQRRANPDSADSPLQFLVKESLRIAVIDTGIGIASEHINKLFQPFIQIDGALNRQYQGTGLGLALVKRIVELHGGQVLLTSEVGVGSCFAIEFEGRHGGIEFEGRHGGIEFEGRHGGTAPTGAPFSPELESQSPPSIKPSDSEQEASPLILLAEDNEANISTVSSYLKAKGYRIILAKNGREAIALAQSENPNLILMDIQMPGMDGLEAMQQIRRYPNLVDVPIVALTALAMTGDRDRCLEAGANDYMTKPVKLKQLATIIQQFLTLKKANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3F8</accession>
    <name>A0A2G4F3F8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate etherase</fullName>
            <shortName evidence="3">MurNAc-6-P etherase</shortName>
            <ecNumber evidence="3">4.2.1.126</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">murQ</name>
        <name evidence="5" type="ORF">CP500_006050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N-acetyl-D-muramate 6-phosphate = (R)-lactate + N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:26410"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="EC" id="4.2.1.126"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-sugar metabolism; N-acetylmuramate degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.126" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56292">
        <property type="protein sequence ID" value="PHX56292"/>
        <property type="gene ID" value="CP500_006050"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00342"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016835">
        <property type="term" value="F:carbon-oxygen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046348">
        <property type="term" value="P:amino sugar catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097173">
        <property type="term" value="P:N-acetylmuramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05007">
        <property type="entry name" value="SIS_Etherase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00068">
        <property type="entry name" value="MurQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005488">
        <property type="entry name" value="Etherase_MurQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005486">
        <property type="entry name" value="Glucokinase_regulatory_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040190">
        <property type="entry name" value="MURQ/GCKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088">
        <property type="entry name" value="PTHR10088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088:SF5">
        <property type="entry name" value="PTHR10088:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00274">
        <property type="entry name" value="TIGR00274"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01272">
        <property type="entry name" value="GCKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="4">
        <location>
            <begin position="59"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="304" mass="32609" checksum="44ADCE59771C9DDA" modified="2018-01-31" version="1">MKNLEQRGHLLTEQVNVNSENLDQLSSIELVDLFNREDAQTLSAIAQSRQHLAQTIDIAAESLRQGGRLFYVGAGTSGRLGVLDAAECPPTFCTPPDLVQGIIAGGAGALVRSSEDLEDRAQDGAEAIAHRQITNLDVVVGITAGGTTPFVAGALQAARQRGAKTVFMACVPIEQVSFEADVNIRLLVGPEIVAGSTRLKAGTVTKMALNIISTGVMVKLGKVYGNRMVDVAVTNKKLRDRALGMLQDLTDLNREEAGFLLEKSGKSVKLALMMHWTNLEREECDRILGEFQGNLRSAVASISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3I0</accession>
    <name>A0A2G4F3I0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56298">
        <property type="protein sequence ID" value="PHX56298"/>
        <property type="gene ID" value="CP500_006085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="167" mass="18989" checksum="C306E636F0E9740D" modified="2018-01-31" version="1">MIPKEDLFTEAAKNWDLERLYQAFAEAKRQISPRSRRGLTETEKLYLRGLLSGCSPAEIARQLLQTSKSAEVYLCKTLYQYVKKIADVPNEPVGNWRNICDRLQEAGYQTQSSVKAKLSSSLPIDALVKIVDMGFENQNTLTIDINIRLEFPSTSETPKTEDLDKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3J1</accession>
    <name>A0A2G4F3J1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56316">
        <property type="protein sequence ID" value="PHX56316"/>
        <property type="gene ID" value="CP500_006190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="212" mass="23687" checksum="9A75D7A764BE3015" modified="2018-01-31" version="1" fragment="single">MNIKNRLKSAVKLTGENLKSGIQKHPDRSLQIPWNFAQVGVVIFPVIPILGALGIFLGLIGTYKQKTSEILRCPVNRGFAILSVLLIITAVFANNRIEAFLGLGNFLPFFIFFATFNRLIQTPTQLRQLSWIIVISSIPVIFLGLGQQFLGWSGIVQLQPVFGWVLEPKGNPPGRMASVFMYANILACYLTIVFILALGLWIEGRRMKEEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3K4</accession>
    <name>A0A2G4F3K4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56315">
        <property type="protein sequence ID" value="PHX56315"/>
        <property type="gene ID" value="CP500_006185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="281" mass="31708" checksum="08750A893B8D7BAC" modified="2018-01-31" version="1">MDELRAALELATEEELQQLTELLFSRRFNPLDYVQTPAPIDVQSRDREAWLDAVEQRFRYLSADGLTVLRGRTEQVTYRQTLIQVCRYLKIPYPKQLSTTDLEAEVFLHLMGHAWKQLPSEEKRALTVRVQRAIVDSKLSEPLPISAEKDPLGLLFKGGSALAVSSIVKPVLLKLMAHQFALHFATYEMAKQAVITGGTAAATQFQNYVAIQTARRGMATSAARYGATRSVFSFLGPVLWTWFLADLGWRSISTNYARIIPTIFALAQIRLTRSECAWELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3M2</accession>
    <name>A0A2G4F3M2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56321">
        <property type="protein sequence ID" value="PHX56321"/>
        <property type="gene ID" value="CP500_005915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="PTHR31118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="243" mass="26750" checksum="32730BA0A166D205" modified="2018-01-31" version="1">MTNQLNSNNLKTIAYSKIVDLTHKIHPNIPIWPGDPPVEFETVAQIETSGYFLRKFSMGEHTGTHINAPNSFDSGGASIDNYPPQSLVVPAIAIDIRDQSLANPDYTLTIDDVLNWEQQHRFIEPGNLIILYTGWQEKWENEKSFFNRDNDGICHFPGFGEAVTQFLLEKRLIAGVGTDTHGVDSGQDESFAVNKQVLEHQGIVLENLANLDQLPAADITLVIGILRLLGGSGSPVSVLAFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3M4</accession>
    <name>A0A2G4F3M4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56346">
        <property type="protein sequence ID" value="PHX56346"/>
        <property type="gene ID" value="CP500_005745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14155" checksum="28AB2309649356B5" modified="2018-01-31" version="1">MPGFGDILQKAVYLGVGLASYAGEKAGSKLNELRAEAEKLADELVKRGEMSTEEARRFVDDMVQQAQQQPPPVEAAGDKKNTEPRRIEIVSEEEDTSGKNTKEVGGVDKLREQVQNLQDELRRLKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3U1</accession>
    <name>A0A2G4F3U1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease adapter protein ClpS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">clpS</name>
        <name evidence="3" type="ORF">CP500_005250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds to the N-terminal domain of the chaperone ClpA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56416">
        <property type="protein sequence ID" value="PHX56416"/>
        <property type="gene ID" value="CP500_005250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00302">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473">
        <property type="entry name" value="PTHR33473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ClpS" evidence="2">
        <location>
            <begin position="16"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="93" mass="10444" checksum="B2CE54C041622456" modified="2018-01-31" version="1">MSVEILVKPTTVRKLAPRYRVLLHNDDFNPMEYVVQTLMQTVPSLTQPQAVNIMMEAHTNGLGLVIVCALEHAEFYCETLNNHGLSSSIESDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3V8</accession>
    <name>A0A2G4F3V8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative glucose-6-phosphate 1-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_006900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:16249"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58247"/>
            <dbReference type="EC" id="5.1.3.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glucose-6-phosphate 1-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.15" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56167">
        <property type="protein sequence ID" value="PHX56167"/>
        <property type="gene ID" value="CP500_006900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047938">
        <property type="term" value="F:glucose-6-phosphate 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09020">
        <property type="entry name" value="D-hex-6-P-epi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025532">
        <property type="entry name" value="G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016020">
        <property type="entry name" value="PHexose_mutarotase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR016020-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="302" mass="32883" checksum="E3A2E075E5000370" modified="2018-01-31" version="1">MSIDQLNTDYGIAGHLTFATGNGGFPVIHIDNGQAKALISVYSGQVLSFQPATETTDLMFLSEKAYYAEGKAIKGGVPICWPWFGPDPEGLGRPSHGFVRNRLWNVVSTSTTPEGATQVILGLQDTEETRAIWPQAFELAIAITVGTTLTVELITRNLGDKAFPLTQAFHTYFQVGDISRVQVLGLENTQYLDKADGGVEKTQVGGVVATGEVDRIYLDVPNELVIDDSSLNRRIRIKSSGSKSAVVWNPWVKISANMADLDDSDYQRLICVETTNAATDIVEVPAHGEFRLAAIYSVERDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Z1</accession>
    <name>A0A2G4F3Z1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56466">
        <property type="protein sequence ID" value="PHX56466"/>
        <property type="gene ID" value="CP500_005475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="216"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="278" mass="31967" checksum="F5D21F36E6C216A4" modified="2018-01-31" version="1">MAYDNTCKYLAEKFPAAFVHWLLPIDEPTSVQVLKTELIQEPIRADSLVFLQTDNQILHLEFETRPYSDPPIAFRMLDYYVRLKRQYSCSINQVVIFLQQTASEQVFVSEYTDANTRHSYRVIRLWEQDPALLLSVPGLLPLATLSQTNSPRNLLEQIATQIATIQEPTQQADLLACTQVLAGLRFEKDLIRQLFRKETMRGSVIYQEIREDGLLEGRKNEALSFLSRLLIRRIGPIAPPIQEQIQTLSVEELEDLGEALLDFSEASDLTNWLSDRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Z4</accession>
    <name>A0A2G4F3Z4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Class I SAM-dependent DNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245901">
        <property type="entry name" value="Tbo703ORF4935P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56504">
        <property type="protein sequence ID" value="PHX56504"/>
        <property type="gene ID" value="CP500_004935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043412">
        <property type="term" value="P:macromolecule modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1139" mass="129461" checksum="299FA27D06D15AEA" modified="2018-01-31" version="1">MNEADRTRVETFITRWEGSSGNERANYQLFFAEMCDALGVDRPLDKGRIPNDPYCFDKDVKIFHPSGQVTSGFVDFYKAEHFLIEAKQGGTTSKKGTAKRGTNTYLREMEKAFVQAVSYTRNLPSKPPFLFTCDIGDHFELWMGFSGDYGGYGARRDIGLTELRKPDVFDLFVDIFSNPQQRNPEKIAARVTREVAADLAELAKGMEANVDPQQVAQFLMRCIFTMFAEDVGLLKEHLFTQALETRWILNPKMFKPEVEALWEAMNEGTSFGFHGQLLRFNGGLFAESQAFALTKAQLEVLLQAAKRDWCNVEPAIFGTLLERALDARERSKLGAHYTPRSYVERLVKPVVMEPLGDRWIAVQAEVKQLLNAGESEPTANQRKKAIAVLEAFLTELQQVKILDPACGSGNFLYVTLDLLKGLESEVLRRLEDVTGSAQLRLDIAQVNPSQFLGIEINPRAAAIADLVIWIGYLQWHFRRFGDIPPIEPVLREYNNIECRDAVLAYDAIEPDVDGLGKVRTRWGGRMMKSPVTGDDIPDPTNQVTIYRYLNPRAAGWQEADYIVSNPPFIGNRKMREILGDGYVETLRKVYKDVPDTVDFVMYWWHKAAEVVRARNVNIFGFITTNSIRQVWQKKVIDFHLLNPKNPLRLIYAIPDHPWTDDGAQVRISMTVCELSNYDTSRLIKLGLVIRESEAEKPENSAEEIKIEWKNAGKIFSNLQAGTDVYSAVSLNGNQKLGCLGVKLHGMGFCLTEAEAKNLETEVIHPYLNGRDLLQFSRKALVIDLFGLTENEVFARYPNVYQWIYERVKPEREKNNRPAYREKWWIFAEPRSSFRPALKTISRYIGSTQTSKHRVFTFIDTKVIPDQKILAIALDDAYFLGVLSSQIHVKWALVCGGQLGPTPVYVQTVCFDPFPFPTPTDTQKQTIRELGERLDSHRKRVQATHPEVTITGMYNLLEKLREGEPLDDKDKAFNQKALVSTLKQIHDELDRAVFAAYDWEPTLTDDQILENLVTLNAQRAEEERNGLIRWLRPDYQAPGETYVQPSLAGIITETEIAVSPTEQQPFPKTLKEQLSAIRDLFRTQSGEWTAAQVTAHFKGANRKQKVILDCLESLEDLGILLSHAENGMTFWHLAEVGSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F423</accession>
    <name>A0A2G4F423_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid oxidation protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56534">
        <property type="protein sequence ID" value="PHX56534"/>
        <property type="gene ID" value="CP500_004605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="16060" checksum="FB0CCD9C79801E2C" modified="2018-01-31" version="1">MSAKDFFHNTVKTSLEKDGWIITDENLFIEVEDVDFYIDLAAERILVAEKTGQKIAVEVKSFLGASDVTEFHSALGQCLNYRSALRLTEPDRTLYLAIPEDVYKDFFTRKFIQRVIVEHQLKLLIFNPTQEEIVQWKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F450</accession>
    <name>A0A2G4F450_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56540">
        <property type="protein sequence ID" value="PHX56540"/>
        <property type="gene ID" value="CP500_004635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="14317" checksum="B26F83458231E57B" modified="2018-01-31" version="1">MSDQIDQSRKIEITGGTVNASGAGALGLGDISGTVANTINQLSDSAKPDEPGIKELLTELKAAIEAETNLYDDDKAEALEQVKTLAEVGQNPQESTMQKAGKTAMKILKGTIAGLPSAATLVEACSKLLPAIASLLLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F463</accession>
    <name>A0A2G4F463_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56574">
        <property type="protein sequence ID" value="PHX56574"/>
        <property type="gene ID" value="CP500_004830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="12"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="209" mass="23780" checksum="7359AB972A6F4B22" modified="2018-01-31" version="1">MTQAVSTKPVTFDEFIDWYPENSENRYELHNGAIVEMPKATGEHSEVSGFLIAELNFEIRRLGLPYFVPKECVVKADNELSGYEPDAIVLDREGTDSEPRWKKQSIITMGSSVRLIVEVVSTNWRDDYGYKLVDYEALGISEYWIADYLGLGGRRYIGNPKQPTFFVHHLVDGEYQASQFRGTDRVVSPTFPELNLTVQQIFTAGRNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F492</accession>
    <name>A0A2G4F492_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MCE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_004735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56558">
        <property type="protein sequence ID" value="PHX56558"/>
        <property type="gene ID" value="CP500_004735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039342">
        <property type="entry name" value="TGD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34675">
        <property type="entry name" value="PTHR34675"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="3">
        <location>
            <begin position="38"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="500" mass="52479" checksum="E2C357267AF4D52C" modified="2018-01-31" version="1">MRSRTVREGSVGFLILVGIGLFGGLVLWLRGVQIGNRTYKFTVEFASVQGMQIGTPVRYRGVAVGKVTTLKPGSNGVDVILEISPGNLVMPRDVAIEANKSGLIGEASIDITPNSILAESLITANPLSGDCPAEIICKNSRLKGQAGVSLDELIRSTVRLTNLYTDPALFNNIKSISENTANTAKGAAKLTQDLSSLTQTAKGEIKTLSESVKVDVNNLSQSVKGELGSLNQSVKGELGSLNQSLKGEAGSLNQSVKKEISGVAADVSQVAKTADSSTKAVSAAAINSANSVTKAANQITLTANELNSLVTTNRSSLVSTLNNLNQASQEIRVTVSSLSPTINRINQGQLLSNLENLSANAAQAAANLRDLSGNVNNPATFLLLQQTLDSARAALQNVHKITADVDEVTGDPAFRNNIRKLLNGLGGLFSSTEQLQQQVKVAQTLAPLSSQLNTNFNPSATAVVSSAKSRVLILQNKPKSPVVPSENAEKSESFGVENNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4G3</accession>
    <name>A0A2G4F4G3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmH</name>
        <name evidence="7" type="ORF">CP500_004395</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56652">
        <property type="protein sequence ID" value="PHX56652"/>
        <property type="gene ID" value="CP500_004395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="50"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="300" mass="33343" checksum="622640695FA16B43" modified="2018-01-31" version="1">MKDIELSEKDTSASDVCIDTYHVPVLGQELIAGLAVRPGGRYLDATLGGGGHTGLILAAAADVTVVAIDRDEQAIRFCQTRFANSPVEFWHGNFAEYQSQDATFDGIIADLGVSSAQFDTPERGFSFRHPAKLDMRMNQQQSLTAEEIINHWDEVKLADIIYKYGEERLSRRIARRIVAQRPFESTTELAGAIASTFPPKQRNGRIHPATRTFQALRIAVNSELASLETFLGEAPKWLKPGGRLGIITFHSLEDRPVKHQLRGTDCLQVLTKKPIIPQSEEVSRNPRARSAKLRLAEKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4U0</accession>
    <name>A0A2G4F4U0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56770">
        <property type="protein sequence ID" value="PHX56770"/>
        <property type="gene ID" value="CP500_003950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="9925" checksum="E8E8265880041852" modified="2018-01-31" version="1">MKSQTSWLEKSVQEFFGNYNWLGKSLETQNGFVPGQLLTLTMPVSEFFRAISWEGIPEVGAMPPPPPMPVISVYEPAEVTIDDLFDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F568</accession>
    <name>A0A2G4F568_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplS</name>
        <name evidence="5" type="synonym">rpl19</name>
        <name evidence="7" type="ORF">CP500_002960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56851">
        <property type="protein sequence ID" value="PHX56851"/>
        <property type="gene ID" value="CP500_002960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14607" checksum="6CA1D2047C411E35" modified="2018-01-31" version="1">MKGAEIIRSLETEEINRVKVELSKVLPEIYVGDTVRVGVRIKEGAKERVQPYEGTVIAMRNGGINETITVRRVFQGVGVERVFLIHSPRIATIQVMRRGKVRRAKLYYLRDRVGKATRVKQRFDRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5A6</accession>
    <name>A0A2G4F5A6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA polymerase I</fullName>
            <ecNumber evidence="2 11">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 17" type="primary">polA</name>
        <name evidence="17" type="ORF">CP500_002885</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2 11"/>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56940">
        <property type="protein sequence ID" value="PHX56940"/>
        <property type="gene ID" value="CP500_002885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="15">
        <location>
            <begin position="6"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="14">
        <location>
            <begin position="387"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="16">
        <location>
            <begin position="777"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="638"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX56940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1032" mass="115358" checksum="80ACC8EFD2B28C94" modified="2018-01-31" version="1">MSSNQTPTIILVDGHSLAFRSYFAFSKSRDGGLRTSTGIPTSVCFGFLKSLLEVMAAQEPEYMAIAFDLATPTFRHEADDTYKAGRPETPEDFIPDLKNLQELLGYFNLPAITAPGYEADDILGTLAKKASEAGYRVKILSGDRDLFQLVDTEKQISVLYLSTDELRRSGKGKSQEFGPEAVKEKLGILPEQVIDYKALCGDKSDNIPGVKGIGDKTAIQLLDAYKTLDGIYAAIDELKGATKKKLEEGKEAAYHSQRMATIVQDVPLEINLEDCQLKGFDEAALIPMLEKLEFKNILNKVKEIQKRFGGVEEKEEGIRKKEEEEKEEGPSTPLMESFRKKEEGISFNSGTGILPVALENSEEEELSFYTLAETIAAQQANKLPIKPRIIQTIEQLNELVQLLQTCTDKTTPVAWDTETTALEPRDAELVGIGCCWGIGETDLAYIAIAHKTGKNLDKAIVINALRPILESEKYPKALQNAKFDRSILRCQGIKLTGVVFDTMLASYVLNPETSHSLSELSKKYLGIVAKSYKELVAKDKTIADISIQQVADYCGMDVYTTFQLVEKLTAELDKQDLRTPTEETGFFTESAGHNEVFLSKNPVSGHPSKSLHRLLLEVEQPLEPILAEMEYCGIRIDSAYLQELSQQLEKRLAELEENTYEAAGRKFNLGSPKQLSEILLEKIPDEFQKKSRKTKTGYSTDAAVLDKLQGDHPIVDDLLEHRTLSKLKSTYVDALPQLVRADTGRVHTDFNQAATGTGRLSSSNPNMQNIPIRTEFSRQIRKAFLPEAGWLMVSADYSQIELRILAHLSQEPVLIEAYQNNRDVHTVTAQLLFEKQEITADERRFGKTINFGVIYGMGAIKFGKSMGKSAADGKKFIERFNQRYSKVFEYLEQVKKEAIALGYVSTILGRRRYLNFDRLSDLKGTNPAEIHPDRLKSLSKDDAQSLRAAANAPIQGSSADIIKLAMIEVNKVLQNYQARLLLQVHDELIFEVPPDEWEELQPKIKDAMENALPLSVPLIVDIHAGQNWMETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5H5</accession>
    <name>A0A2G4F5H5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA uptake protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57010">
        <property type="protein sequence ID" value="PHX57010"/>
        <property type="gene ID" value="CP500_002130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013720550" evidence="2">
        <location>
            <begin position="22"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="343" mass="36787" checksum="5CF8254EB9375284" modified="2018-01-31" version="1">MFSTFRLLPTATATAILVALAGCVSTPTASNTESTASPTATATPVATSEHSMNHGGKGVININTALLSDLDKIEAKLGVPALSNKIQASRPYGKVEELVSKNVITQPQFDQIKDMVTIQDVVLTGEAKDVDFMTKMGLMKGHLFVAKELLDQSKPDQAEPHIGHPVEEIYADVEDQLNERKIPEFKTTLIKLQDLVKAGAKDPAQVNAEFTASMQAVDGSIAAVSEAQRKDPKFVLQVINGLLDTANSEYGAAVAGGKISAIIEYQDSRGFVMYAEMLYKDIASQVAKTSPETDKSIVASMTELKKNWPTAIAPAAPVKTTEQITKLIKTIETDSQKVLKPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5J9</accession>
    <name>A0A2G4F5J9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldoketomutase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Glyoxalase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Ketone-aldehyde mutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Methylglyoxalase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-D-lactoylglutathione methylglyoxal lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gloA</name>
        <name evidence="8" type="ORF">CP500_002185</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-S-lactoylglutathione = glutathione + methylglyoxal</text>
            <dbReference type="Rhea" id="RHEA:19069"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="ChEBI" id="CHEBI:57474"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="4.4.1.5"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57018">
        <property type="protein sequence ID" value="PHX57018"/>
        <property type="gene ID" value="CP500_002185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004361">
        <property type="entry name" value="Glyoxalase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00068">
        <property type="entry name" value="glyox_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="7">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14777" checksum="C326237C93567718" modified="2018-01-31" version="1">MQLLHTMLRVGNLEESVKFYTQVLGMKLLRQKEYPDGKFTLAFVGYGEESDHTVLELTYNWGVEKYNLGDAYGHIAIGVDDIYGTCNEIKTRGGKVSREPGPMKHGSTVIAFVEDPDGYKVELVQLKNRCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5P7</accession>
    <name>A0A2G4F5P7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57076">
        <property type="protein sequence ID" value="PHX57076"/>
        <property type="gene ID" value="CP500_002010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="158" mass="17048" checksum="D3245F7DF7EA0F40" modified="2018-01-31" version="1">MLNSWRLNAIIAAMFIQLIASNNKSAIAQEREGCFIVNSAGEVINLNQLCSTQEPTVKISGNDGKFVEDYKRLAKSYSTATTDSLLQGIQSSPGQKIATAKRMCTEAKAGLSLSEFKLRAIGQAASMENPIAKESFLADADITLTLASNHYCPELASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Y2</accession>
    <name>A0A2G4F5Y2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57158">
        <property type="protein sequence ID" value="PHX57158"/>
        <property type="gene ID" value="CP500_001825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019303">
        <property type="entry name" value="vWA_TerF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10138">
        <property type="entry name" value="vWA-TerF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="6"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="22485" checksum="1F71EC2DFAEA8219" modified="2018-01-31" version="1">MLLNRDYTIIIDKSGSMYTKDKTGGKSRWALMQESTIALANKCEELDPDGITVYLFSGRFKRYDNVTAAKVVQIFQENEPSGTTNLAIVLQDALNNYFQRKISGRTQQNGETILVVTDGEPDDRKEVMKTIIEASRKLDRDEELAISFIQVGNAPEATKFLKILDDELQSAGAKFDIVDTVTMDDMEGMTLTEVLLNAITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F622</accession>
    <name>A0A2G4F622_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="10">APRT</shortName>
            <ecNumber evidence="5 10">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">apt</name>
        <name evidence="12" type="ORF">CP500_001305</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5 10"/>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57189">
        <property type="protein sequence ID" value="PHX57189"/>
        <property type="gene ID" value="CP500_001305"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="11">
        <location>
            <begin position="26"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX57189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="18573" checksum="C386B0158FB91072" modified="2018-01-31" version="1">MDLKSLIRDIPDFPKPGIMFRDITTLLRNPQGLSYTIDSLAEKCSEMSPDYIVGMESRGFIFGTPLAYKMGVGFVPVRKPGKLPGAVYFAEYELEYGVDRLEMHQDAMTPGSRVLIVDDLIATGGTAAATVELLEQAGCELVGFAFAIELLALGGRHKLPDVPIVTLVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F627</accession>
    <name>A0A2G4F627_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57243">
        <property type="protein sequence ID" value="PHX57243"/>
        <property type="gene ID" value="CP500_000965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028348">
        <property type="entry name" value="FAD-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42842">
        <property type="entry name" value="PTHR42842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038984">
        <property type="entry name" value="FAD_binding_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="212"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="538" mass="58816" checksum="F6764A6DE511B7C7" modified="2018-01-31" version="1">MLRVTEIKLPLDHPVDTIATAILKKLQIPPEELIGYSIFKRSYDARKKPEILLVYIVDVETTQEKQILARFTKDPHVIVTPDMSYRYVAEAPRNLTIQPIVIGTGPCGMFAGLMLAQMGFRPILLERGKAVRDRTVDTFGFWKKKTEFNPESNAQFGEGGAGTFSDGKLYSQVKDPQHYGRKVLTELVNAGASTEILYINKPHIGTFKLVGIVQSMRAKIESLGGEIRFQTRVADIHIENGKVQGLTTASGEYIASNYIVLAVGHSARDTFEMLFSRGVYIEAKPFSIGFRVEHPQSIIDRCRFGDRASHKLLGAADYKLVHHCQNGRSVYSFCMCPGGLVVAAASEPGRLVTNGMSQYSRNERNANSGIVVGITPEDYPGHPLAGIEFQRRLEERAFELGGGTYNAPGQLVGDFLANRPSTALGAVQPSYTPGVVMTDLSESLPDYAIAAIREALPAFDKQIKGFAMDDAVLTGVETRTSSPIRIKRKEDYQSLNTDGLYPAGEGAGYAGGILSAGIDGIKVAEAVALSILRENHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6E4</accession>
    <name>A0A2G4F6E4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CpeR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57342">
        <property type="protein sequence ID" value="PHX57342"/>
        <property type="gene ID" value="CP500_000755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="11868" checksum="1D5213CBA485B602" modified="2018-01-31" version="1">MLPPQAQKKLQCWIRSRHLICSGNFYLFETIDYSAIERFTESIRALGGTLISVDAIDKIWMGDHRQVILYRAKASLHTPCHNLKQYWFKYGSFHTRFDPSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUC4</accession>
    <name>A0A2G4EUC4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_023115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000266">
        <property type="protein sequence ID" value="PHX53139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53139">
        <property type="protein sequence ID" value="PHX53139"/>
        <property type="gene ID" value="CP500_023115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="460" mass="51955" checksum="4FB27E19F738E7CE" modified="2018-01-31" version="1">MELFEEQKRCLDCLVRSIEQLGGRVDIPKFEEIAELIIQTMRGPWRYFHTSEHIFEVGGSVDPIEVLAALFHDLVYVQVDEVNFNIISALCPFVKEVRSELVIRDEAELPKDAIYQLVATLFGFIPGQTLSPFAGQNEFLSAVIAGKCLEPFLPPSAIVQITACIEATIPFREVSANGLSAIELLHQRLINTNRDFNLGFTDPELCEIVKRSVRLANRDVENFASPNSSNFLDNTWNLMPETNHELSNFNSYTVGGYRKSLQKMEGFLNFLKPELVFQQFMGYPDDETYADMISRTRNNIEVAKLYLGVKLITIAILEALSYRLGRDIPLSTMMGELRAPGVTTSALEDYLPNIHILYPLENQLQEQVLALLEIGRNQESPYDIKNSPVSTFIIKSIGFAETGNFLNKAHEFFADRIASEDLLSYCDAEVIDTIEIGVVKLFESRKIALRKVQLAHKVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUZ9</accession>
    <name>A0A2G4EUZ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000218">
        <property type="protein sequence ID" value="PHX53308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53308">
        <property type="protein sequence ID" value="PHX53308"/>
        <property type="gene ID" value="CP500_022195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8331" checksum="6D8FEF76EBA163A2" modified="2018-01-31" version="1">MQRLGLLAPPLLRAARGAYRLYLELHYEQMQRPTGMVVCLGRDRAQLIFTSQPILLPGECFVTFEEIESQMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV84</accession>
    <name>A0A2G4EV84_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_021520</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53444">
        <property type="protein sequence ID" value="PHX53444"/>
        <property type="gene ID" value="CP500_021520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="79"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="283" mass="31388" checksum="472C7258A23C1BAD" modified="2018-01-31" version="1">MTKLDLRVRAIGKKWLWIQATLAFAFLYLPILILIIYSFNTSKFNAVWRGFTFDWYRSLFSDAGTLGIGSSSAGIWTALNNSLVIAVISTLLATIFGTMIALALERFHFPGRKMVETLLFLPIIMPEIAIGISLLVFFTLVFRIIENLTGIRLNLGLPTVIIGHVTFNISFVTITVRASLAELDPILEQAAFDLGANEWRTFWRITFPLIWPGIFSGALLAFTLSLDDFVVTFFTTGVGSMTLPLFVYGMIKFAVTPAINAISTLMLLASLLLVVSSLKVKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVG8</accession>
    <name>A0A2G4EVG8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021345</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000193">
        <property type="protein sequence ID" value="PHX53468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53468">
        <property type="protein sequence ID" value="PHX53468"/>
        <property type="gene ID" value="CP500_021345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018449">
        <property type="entry name" value="NIL_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09383">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00930">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="106"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="14761" checksum="92865F01BF6E5994" modified="2018-01-31" version="1">MKKRVTLTFPQRSIQMPVTYRLAKDFNVAANIIRAQVAPNQVGKLVLELAGDIDQLEAAIDWLRSQNIGVSLANREILIDEDSCVHCGLCTGVCPTEALTLDPESFRLSFARSRCIVCEQCIPTCPVQAISTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVL2</accession>
    <name>A0A2G4EVL2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53592">
        <property type="protein sequence ID" value="PHX53592"/>
        <property type="gene ID" value="CP500_020685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="2"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="137" mass="15920" checksum="D345CB9EAE9ED24C" modified="2018-01-31" version="1">MILCDAGVLLCLVDRTQPQHIAYRNAVMPLAKPLVTTWSCLTEAMYLALHRGGWMMQKHLGQLLLDKMLTIYEIQECDYSRLLELMEQYRDQPMDLADATLVLTAEKTGYRQILTLDSDFLFYRIGNRDSFDIIQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVN8</accession>
    <name>A0A2G4EVN8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methionine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000174">
        <property type="protein sequence ID" value="PHX53601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53601">
        <property type="protein sequence ID" value="PHX53601"/>
        <property type="gene ID" value="CP500_020630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="306" mass="35971" checksum="D18D207E08974104" modified="2018-01-31" version="1">MNRGIYIVANDKVIESAIALTNSIRLYNCQVPVFLIPFDDNYQQVAATLSTLHGVRLFPNLEFVEQFTREIGQMFDRNFLALPNKMRKLAVWFGPLDEFLYIDTDIIVFEDIAANLDKLSEVDFFCCDYHHLSEKLRNVFSPLVKQQHIFTDSQLQDVFNSGFWASRKGTISESQMHEVLRECSQHREYFDFTQNVTDQPILNYIILKLIPKRCNLVKNSETEPGSWAGSKHFQEIDYVLYDKGKRLKYLHWAGIPIKSGSPYWTLWKHYRYLNEDKPNLVQKIFRYLQGVLSAIIRYCRVCWALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVU7</accession>
    <name>A0A2G4EVU7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000218">
        <property type="protein sequence ID" value="PHX53307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53307">
        <property type="protein sequence ID" value="PHX53307"/>
        <property type="gene ID" value="CP500_022185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="15031" checksum="D4486FE360C729FF" modified="2018-01-31" version="1">MLIKLAETQLSGILSYCRQIFITRRAHSLSLLFATGLGLSVIVAGCSPTATTTDTATKPTTPTNSAAPAKSVTVNIGYQKSATVLNALKTKGDLEKALAASKSSVKFVEFPAGPPLLDRNTCNQYPRRPWQSYWATSKHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVX3</accession>
    <name>A0A2G4EVX3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heme A synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_020165</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000162">
        <property type="protein sequence ID" value="PHX53692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53692">
        <property type="protein sequence ID" value="PHX53692"/>
        <property type="gene ID" value="CP500_020165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="303" mass="32378" checksum="6B787B5CA16A9689" modified="2018-01-31" version="1">MANSVLNQPTAAEVEWQPKDIVRGLVWKIAIATWLLMAVGSATRVMNAGLACPDWPLCYGQLIPAAQMNLQVFLEWFHRLDAAAIGLSAIGLLGLSLFYRSRLPKWLPIASAGAVFLIVFQGILGGLTVTQLLRFDIVTAHLGTALLFFCALLVIGFMLTPYEATGNTGKLAWISSIAALLVYLQSLLGALVGSRWALHQCFGSSELCSVMNSHIIGVVPATAATLVVAIMAWRQPALSANLRKLGNLASVCLVAQLVLGLATFRLHLQVEPLTVAHQAVGAALLGTLVAFSVVAWRDRVLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVZ0</accession>
    <name>A0A2G4EVZ0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000171">
        <property type="protein sequence ID" value="PHX53620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53620">
        <property type="protein sequence ID" value="PHX53620"/>
        <property type="gene ID" value="CP500_020505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="13480" checksum="E693F9470394F498" modified="2018-01-31" version="1">MQLTERHIIKSTEHRFAQIDELAFKSKNLYNAANYVIRQSFIYGWGYVSYNEMNRLMKSHEAYKAMPAKVSQQILMVLDKNWKSFFEAVKAYKVDSSKFTSRPKLPKYKDKVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVZ9</accession>
    <name>A0A2G4EVZ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53705">
        <property type="protein sequence ID" value="PHX53705"/>
        <property type="gene ID" value="CP500_020100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14177" checksum="78415F8CC09C7797" modified="2018-01-31" version="1">MTFEYKAALVTLADIENEVLVKFYKRFLDIEPNPYIPNTYAEFQLPGLRLGIFKPKNSHKSEFSGIGKTGMSLCLEVSDIEIAIARIWTLGCPPPGEIITASHGLEIYAFDPLGNRLILHQSHDNVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWJ6</accession>
    <name>A0A2G4EWJ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000180">
        <property type="protein sequence ID" value="PHX53547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53547">
        <property type="protein sequence ID" value="PHX53547"/>
        <property type="gene ID" value="CP500_020940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="21168" checksum="99FE74C4F0425433" modified="2018-01-31" version="1">MTATIRSTDSRGPRAARKPTVGSTNSKVTSIAQRKRAKTGPVLPNYSATEPAQALPRREASVLKVLPNSRFQPAWLRSLVQVQRASSVAVMLILGGALSLYGLTVYNEQRWSQEYQKLETLRLREQQLSAASEVLKHQLAKEAENPETGLASQKPGEMIFLEPVPVGRSPQPTIIPSPEPARSSQGAIETPLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWY2</accession>
    <name>A0A2G4EWY2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000137">
        <property type="protein sequence ID" value="PHX53950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53950">
        <property type="protein sequence ID" value="PHX53950"/>
        <property type="gene ID" value="CP500_018765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="7219" checksum="81125F2C5EA4235B" modified="2018-01-31" version="1">MILNIYGSDVGGYPGLFIRNNLTKEATESAEEEKREMIFFNSMNFILVIDSMPLIRYNYYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX00</accession>
    <name>A0A2G4EX00_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3153 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54075">
        <property type="protein sequence ID" value="PHX54075"/>
        <property type="gene ID" value="CP500_018095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021499">
        <property type="entry name" value="DUF3153"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11353">
        <property type="entry name" value="DUF3153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="273" mass="30195" checksum="D631EFCF7FF0A808" modified="2018-01-31" version="1">MKQEIVKDETGKRKKHFLFLLPFVLCLLTLVTGCVQYDVGVNFESQTRGEIVQHIKLGERLTSFSSEIVGDWLESVERRVRSLDGKTKRLSEGEVLVTIPFNNGAELEEKFNAFYNPAQTNKSRFASPIETDLPKFESHLNVKQNNLLLVLRNRLSLELDLRSISLLSANGDMLLSPGGLLELDFSLNTPWGAESIETAPGALVPASYAEGKQLVWKLKPGEINYLEAIFWIPSPVGIGTVIIALLVFAGIGLKYQLLPAMGIGAKTPKIAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX33</accession>
    <name>A0A2G4EX33_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000130">
        <property type="protein sequence ID" value="PHX54038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54038">
        <property type="protein sequence ID" value="PHX54038"/>
        <property type="gene ID" value="CP500_018245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="13365" checksum="2DAD9AEA7FE7F93D" modified="2018-01-31" version="1">MGLNEYFDFLAADDIRIKGHRIGIETVLYEYLYRERTAEEIQQLYPSLTLAEVYTTILYYLLNNESVSRYIQDWLEWSHQQRKIQAANPHPTTERLRKLKAERERQTAIQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXD5</accession>
    <name>A0A2G4EXD5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_017410</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54189">
        <property type="protein sequence ID" value="PHX54189"/>
        <property type="gene ID" value="CP500_017410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="13">
        <location>
            <begin position="3"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="11">
        <location>
            <begin position="165"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="12">
        <location>
            <begin position="290"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX54189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="366" mass="41454" checksum="0E8B24E6A45549ED" modified="2018-01-31" version="1">MFAVKRALKLNNNEATLMARHAGFRRVVFNFGLSLRTQMYSEGKFTDSKVINEVKKVLTNYIKKQPEFGWMNQLSSRVYQNALIDLKDAFSRYRSVQAGYPRFASRRDGQSFRVDSSNGKVLLSAGNTIKIPTLGTFRLYEALECGYVSQTFTISKEGSRWFVSFCVDAERLPVQQSQASVGIDVGIKSFATLSNQQVFDAPKPLKQAKTKLAKLQRQASKQVKGSQNQRKTYDMISLLHARIARIRLDFLHKLTTYLAKNFKLIKIENLNVQGMMANHKLAGAISDLGFYEFKRQLDYKCQMYGASLVLVDQWFPSTKTCSNCGHKKDMPLSVRTFDCPACGRSLDRDLNASLNILNWEPKAIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXJ7</accession>
    <name>A0A2G4EXJ7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HEPN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54272">
        <property type="protein sequence ID" value="PHX54272"/>
        <property type="gene ID" value="CP500_017020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007842">
        <property type="entry name" value="HEPN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05168">
        <property type="entry name" value="HEPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN" evidence="1">
        <location>
            <begin position="7"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="143" mass="16392" checksum="F5C90099AE6C8427" modified="2018-01-31" version="1">MQESFSNSAGRHLHDAQLLLGEQRWDNAVYLAGYVVECSFKVLVEQHFKHDRDAVKKYGHDLTELEGRAMERVRVLYPILDRQLPASRIADTILAQNHPERRYSKSGLWAEAEAQTAVQRAEEIYREIISKLVLNGSISSQDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXN2</accession>
    <name>A0A2G4EXN2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metal ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54302">
        <property type="protein sequence ID" value="PHX54302"/>
        <property type="gene ID" value="CP500_016845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="133"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="346" mass="37588" checksum="1EA18848A864B6BA" modified="2018-01-31" version="1">MLKNLTEKTRRCFGMAVLAIAFRLVGCTGSPQTTNPTPQNPVANLPKVVATTGVICDITKKIAQSAIDITCLIKPGDAPHAYQIKPEDRKAIETGNLILFAGYEHEPSIIQLIKSTTNSAPKIAVHELAVPKPLMGEHEHEEGQKTEEKPHTAGEKVPDPHVWHNPQNGIRMVEVIRDELKKITPKNTELYTSNAAKLTTNLQKIDTWIKAQIATIPADKRKLVTTHDALSYYADAYGLEVAVALQGVTTEEQPTAARIAQLLSEIKTSGVPTIFVEVTTNPKLMETVAREANVKISDKELYSDELGSPGSGADTYEGMLTTNTCAIVSGLGGTCSSFTESRSYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXQ1</accession>
    <name>A0A2G4EXQ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2605 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000139">
        <property type="protein sequence ID" value="PHX53937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53937">
        <property type="protein sequence ID" value="PHX53937"/>
        <property type="gene ID" value="CP500_018835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019728">
        <property type="entry name" value="DUF2605"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10792">
        <property type="entry name" value="DUF2605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="12342" checksum="FAD0F0E835EA30CD" modified="2018-01-31" version="1">MLNPNLPESELLKSILQPLLEDFRDWFGRSATLLETNEIAFLTREEQSDLLARVKQVQQEVSAANALFQATGGQVGIETATLMPWHRLLAECWKVSARFRSEQSVKLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXS2</accession>
    <name>A0A2G4EXS2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter ATP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_016740</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of an ABC transporter complex. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54321">
        <property type="protein sequence ID" value="PHX54321"/>
        <property type="gene ID" value="CP500_016740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006824">
        <property type="term" value="P:cobalt ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005876">
        <property type="entry name" value="Co_trans_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01166">
        <property type="entry name" value="cbiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="9"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="285" mass="32308" checksum="5E11EB1B7D9FF14E" modified="2018-01-31" version="1">MPNSPCPILEFDRTSYQYPCNLGSTIQGLSLKVPTGKRCGLIGQNGCGKTTLFLLANGLYQPQAGTVRWEGEPFRYDRKSLTKLRQQIGLVFQNPEHQLVASTVEEDISYGLYNLGLTEPEVAKMVQEAIGQFDLTELANQPIHKLSLGQKKRVSIADIMVLKPKLLLLDEPTAYLDPRHTRKLIGLLQQIHATGTTILLASHDLDFIYRWADWVFVMDRGQLILEGTPETVFAQREVLEELQLGVPLAIELMEQMKAIVEHDDNSKMHTFEKWQQQILQAQRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXU1</accession>
    <name>A0A2G4EXU1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="8 10">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">hisA</name>
        <name evidence="11" type="ORF">CP500_016680</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8 9">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="8 10"/>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54352">
        <property type="protein sequence ID" value="PHX54352"/>
        <property type="gene ID" value="CP500_016680"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006063">
        <property type="entry name" value="HisA_bact_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00007">
        <property type="entry name" value="TIGR00007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="257" mass="27025" checksum="78D462F9D79CF2D9" modified="2018-01-31" version="1">MNVIPAIDLLDGKCVRLYQGDYAKSQTFNDNPVEVARQWVNEGATMLHLVDLDGAKAGHPVNQAAIEAIVRAVDVPCQVGGGMRDRTSVAAILNLGVRRAILGTVAVEQPQLVGELCAEFPGQILVGIDARNGKVATRGWLETSAVLATELAQQMAKLGAAEIIYTDIHRDGTMEGPNLESLREIANAISIPVIASGGVSSIADLLSLLALEPIGVKSAIVGRAIYTGDVLLKEAIQAVGQGRWQDVPPDLGSSSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY66</accession>
    <name>A0A2G4EY66_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OprB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54461">
        <property type="protein sequence ID" value="PHX54461"/>
        <property type="gene ID" value="CP500_016015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038673">
        <property type="entry name" value="OprB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLH" evidence="3">
        <location>
            <begin position="135"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="660" mass="71887" checksum="98E860E3F649C9DE" modified="2018-01-31" version="1">MTKNTDSFQALWLSLLISGVALPLSPIATIAQVQDNSTSEVAIESSPVNGSPSDETLRAVEVEPSQLPEIDTAETVTTEPKIMGTIRKLPPKELETANIPQPQKVAEVSTVADINSEINTADNLSIQQEAAQVTSVSQLSDVRPTDWAFQALQSLVERYGCIAGYPDGTFRGNRAMTRYEFAAGLNACLDQITKQISVSTANLVKKEDLLALQKLQEQFAVELATLRGRVDALEARTSELEANQFSTTTKLSGFAWFNMTGAFANDKVRVEATDRNAVPVARTGGRDPVTNRPIVQKVDNPEITFSQLVWLTLNTSFTGKDQLITQLAVGNGNSPANQFTSAGLFNTFGTPFLDQTAGNNPNEVVLRELSYRFPVTNSLQVVVGPRINFYRYFDNNNFNFFVDGASSFNSNNSTLLTATKRGAGALALWELSPQFKLRLGYLGESMEFLPSSVFNSASNPSQGLFNATNTSTVELTFSPSDRANLRFLYSRSNIRQIGGLIGAPVGKPINGLADDGFGGKVGDATANTFSFNFDWSLTRRFGLFGRYGYGETNIFPRTNRPDGTIKTQSYQLGVAFPDLIKKGALFTVSFLVPFDVTGGRRFLVSGGGNGGTQYEVEANYYLPVTDNISIVPAFYVIGNANNFDNNPTIFVGNLRTQFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY99</accession>
    <name>A0A2G4EY99_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system ParD family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54515">
        <property type="protein sequence ID" value="PHX54515"/>
        <property type="gene ID" value="CP500_015730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022789">
        <property type="entry name" value="ParD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36582">
        <property type="entry name" value="PTHR36582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03693">
        <property type="entry name" value="ParD_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02606">
        <property type="entry name" value="antidote_CC2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10446" checksum="CC013E84D1252652" modified="2018-01-31" version="1">MNVSLTPELEKFVQQKVKTGRYLSVSEVIREALRLLEERDMQRQMRIEKLRQEVAVGIEQSDRGEIFDGEEVVAEILEEIELEERAINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYJ3</accession>
    <name>A0A2G4EYJ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PEP-CTERM sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54566">
        <property type="protein sequence ID" value="PHX54566"/>
        <property type="gene ID" value="CP500_015385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026374">
        <property type="entry name" value="Cyano_PEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04155">
        <property type="entry name" value="cyano_PEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013599319" evidence="1">
        <location>
            <begin position="28"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="225" mass="23151" checksum="B7F3390ABA618CD4" modified="2018-01-31" version="1">MNVCQKLGIVGGSLSFAVVSQCFSVQAATLTQTYTVDLGSQPLNSSTNVVLPKFNSLLGTLLRAYVTVKSTVNNTVSITPLTGDFMGTAATNASIAVNIPLLKVDPNLTLSVLASPPETRIANGATGSVSGSASGTVSKSYDSQQSLSALSGCDGDTFIAGLMTTGLTQVTGNPVRGSFDGKVIANTTVSAIYEYEPVPEPMTAVGTFVAAGMGLWWKRRASKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYM2</accession>
    <name>A0A2G4EYM2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54624">
        <property type="protein sequence ID" value="PHX54624"/>
        <property type="gene ID" value="CP500_015210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="154" mass="17260" checksum="B3E3893E7B654AEA" modified="2018-01-31" version="1">MNETQDEIFQAFIVALVQQTEQLPADVQSEFNKTDETCTVTDILRLTKLHPPLLAAYQNNRVWLKNHSNERSKGLDVLPDAEFEINNTTNIETDNSASDISDLTDLPKILNQIEAKVQPRGFKAFLGKILQAKDSVQASRDTILLSIADGLIHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYV7</accession>
    <name>A0A2G4EYV7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54691">
        <property type="protein sequence ID" value="PHX54691"/>
        <property type="gene ID" value="CP500_014840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="13187" checksum="CB8CF4724A75ABAC" modified="2018-01-31" version="1">MNRGVFLVLLAAILCGVVGQFSLKAGAKILGPIGAANLVEKVIAMATQPLIIAGLGLYAISSIGFIVVLSRANISIVSPLLSISYLFTVLGGKIVFNEPLPPLRLVGVGLIMTGVIFVLRGQAGGATGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ94</accession>
    <name>A0A2G4EZ94_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_013975</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54832">
        <property type="protein sequence ID" value="PHX54832"/>
        <property type="gene ID" value="CP500_013975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="259" mass="28300" checksum="A14CF2ACD83928CD" modified="2018-01-31" version="1">MSLLEAQQLTMRFGGLTAVNQVSLTLEKGSIASLIGPNGAGKTTFFNMLTGIYKPTAGQLILENKNITGLPPDRLTTFGIARTFQNIRLFNNMTVLDNILVGRHCRLKAGLLGAIFRSPAVNLEEREAKKKALNMLDFVGLGAAKAPELAKNLSYGDQRRLEIARALASDPKVLLLDEPTAGMNPNETADLTRFIYRIRDELDLSILLIEHDMKVVMGISDRVSVMEYGTKIAEGTPAVVRADPRVIEAYLGKEEDANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ99</accession>
    <name>A0A2G4EZ99_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54836">
        <property type="protein sequence ID" value="PHX54836"/>
        <property type="gene ID" value="CP500_013995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="477" mass="53535" checksum="A5C2D3350E9D94DE" modified="2018-01-31" version="1">MFSKTTIRNFTIALLTALILELCSPIAIFAQNIETIKFSGTAAGVSTRYIGAVEGNINFDLKDLQDLGINTYRIYGGMSRWEPEDDDGKYGLPSIEQIKTNPKIINWAHWDKMMTNPPNGSDYWWSGKPGTVWKGNAKTIFNSLKQAKIRPVVSIRNVDNSWSPSWALQLNPPRNQEDWNEWWEHVFATVYWLNVRNDYGVDDWEIHNEPDNREQGWGGTRADYFELVKVAKDAIDFVYKTYLPSRTYHIHGPKTVGGSNWPAVALQEIPNYFDIVNVHNYDADISNYTRKVHGWMNGTVRVDSPLWLGEWGSYEISYSDLSLALNLIKNLIRGSQPGDNYVYGSHIFCLYDWGKPGVAEGLLGSDGKRRAGYYALRMGIRALQGGKSTFFPIANSANLMAVATKDANNHVYLLAVNDQPKSYTVNADISALLKVGKGTVREFSSRAMDEVVGNLALKDGNATFSVAGNSAVLIKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZH1</accession>
    <name>A0A2G4EZH1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ParA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54888">
        <property type="protein sequence ID" value="PHX54888"/>
        <property type="gene ID" value="CP500_013715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="4"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="299" mass="34105" checksum="4A1F1D482D75CEC6" modified="2018-01-31" version="1">MTPKSIAVINFKGGVGKTTVTWSLGNIISQSTDLEVLMLDLDPQMSLTEAIGLNESTGHLDDKFGNWYEKSLRERRTIYDALELYKKNGQNFKFPVGFDTIYEIDEQLHFVPSVEELYWLDLDGFEGKNVKDFIRRFIGKITNSANSINSANSPNLPKYDLMLFDCSPSFSLLTYSVLSCCDLVLIPVNPDYFGSRGLSLVLNSLQKRIEPYPFPKIAVFMNKAKIYGGILTNEVQFYIREVKRLCADISNDNNIEVKFLESTIRESVGLKRAINEGELPRELVREFELLWAECAEYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZI4</accession>
    <name>A0A2G4EZI4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1778 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54597">
        <property type="protein sequence ID" value="PHX54597"/>
        <property type="gene ID" value="CP500_015270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014795">
        <property type="entry name" value="Vibrio_phage_ICP1_Orf50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35401">
        <property type="entry name" value="PTHR35401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08681">
        <property type="entry name" value="DUF1778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="10843" checksum="5853E36A4699D714" modified="2018-01-31" version="1">MTKTTKSEPSALLEARVSPEIKALWQKAADLEGRTLTDFVIASVQAVASKVIEQHQRLKLDLDDSEAFVNALLNPTQPNQALKAAALRYKQVMGDGTHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZK3</accession>
    <name>A0A2G4EZK3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SRPBCC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54942">
        <property type="protein sequence ID" value="PHX54942"/>
        <property type="gene ID" value="CP500_013375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="17272" checksum="5B61441F6F391055" modified="2018-01-31" version="1">MSIRQVFEQSIEIRAAATLVERCIADRTLMHKWLNPVLRCEPVGEWDTAVGSRSLFIIQIPVWQPTLESVVLEREPGLVVWGFDGFFKGCDRWECQPQIQGTLLINRFEFEIPNPLIRYGFNRFAAHWTQKDMKDQLRRLKRVAEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZM5</accession>
    <name>A0A2G4EZM5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_013135</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245729">
        <property type="entry name" value="M.Tbo703ORF13135P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54963">
        <property type="protein sequence ID" value="PHX54963"/>
        <property type="gene ID" value="CP500_013135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="456" mass="51866" checksum="43024780E4C16C09" modified="2018-01-31" version="1">MNPTMYAQQLELFDLFNATSKNTRSQLTFVDLFAGIGGFRIPLEELGCKCLGYSEIDKKAIQVYRDNFIKDANSDEVYLGDITNLNQLPFAIDLLVGGVPCQPWSIAGKLQGLDDPRGKLWTDVFRVVTANHPKAFIFENVKGLTEPRNIESLKYIIDNLTSSGYVVKYEVLNSYDFGLPQDRDRMFIVGIRNDLERCWGFTFPKPIDSAIKLYDVIPGIQRSNFQKQKFSPTVLFDGKIPGSRGRFQKLDELNDFFLFTDIRDGHTAIHSWDLIETTSREKLICQTIMKNRRKNIYGEKDGNPLEFKVLATLIPELKQTEIDNLVDKEILRSVDEKGYDFVNSKISSGINGISKIFLPHADAIATLTATGTRDFVATISIQCQEPLAYKETFIREIYQKKNFQPLTAQDYAKLQGFPEWFKIDDNENTAKHQLGNAVSIPVVYHLAKALLEIILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F037</accession>
    <name>A0A2G4F037_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000064">
        <property type="protein sequence ID" value="PHX55121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55121">
        <property type="protein sequence ID" value="PHX55121"/>
        <property type="gene ID" value="CP500_012485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="136" mass="15655" checksum="AD8AD44A04796AAC" modified="2018-01-31" version="1">MTVANEQITKSISNSGLSNFRITVERLIELLDLEEEDEYGVLRPTEYAFRTAMKLVVEAYYSMGNSFPKCSTGTDDQGSITLDWTSLEPERTVRLFCPFSAEQPVDIYHHTKNENVVEDILSSSTLVYWLQWFNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F047</accession>
    <name>A0A2G4F047_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_012465</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000064">
        <property type="protein sequence ID" value="PHX55118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55118">
        <property type="protein sequence ID" value="PHX55118"/>
        <property type="gene ID" value="CP500_012465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="956"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="892"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1124"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1163"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1668"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1125"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="994"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1716" mass="184950" checksum="E1BF60F19784B097" modified="2018-01-31" version="1">MTNSQENPELDGIAIIGMAGRFPGAASVDELWQNLCGGVESTTLFGDAELDPSIDPNLRQNPNYVKARGILDGADRFDAAFFGVSPREAEITDPQQRIFLEIAWAALENAGCDPNTFNGSIGVYAGTGNNTYFPNNIAGRSDVISRAGEFQVMVGNEKDYIATRTSYKLNLKGPSVSVHTACSTSLVAVCQAFYALMSYQCDLALAGGISITVPQNSGYLYQEGGMFSSDGHCKPFDAKAEGTVFGNAAGAVVLKRLEEAIADRDTIYAVIRGVGLNNDGAAKVSFAAPSVDGQADAIAMAHAMAGVDPETISYVETHGTATPLGDPIEIEALTQAFALACDLKSTAKQFCAIGSVKSNFGHTIAAAGVTGLIKTALALKHQQIPATLHFEQPNPAIDFANSPFYVNAELSEWKAGKTPRRAGVSSFGVGGTNAHVVLEEAPALEPSSPSRPRQLLLLSAKTPSALDAATGNLRSHLAQHPEIDLADAAYALQIGRQAFNYRRFAVCSDRTDAVQVLESLPPLRTATRCTESRNPAVIFMFPGQGAQYVNMGLNLYESEPLFRSTVDRCAEILQPHLGRDLRKVLYPGSDEATAAESLRQTFLTQPAIFTVEYALSKLWQSWGVIPQGAIGHSIGEFVAATLAGVFSLEDALMLVAARGRLMQDLPGGSMLSVRLPAAQVEGRLSADLAVAAVNAPDLCVVSGPTEAIALFQQQLESESVVCKQLHTSHAFHSPMVDSIVEPFAEYVKKVQLSAPTIPFVSTVTASWITAEQATDPMYWARHLRATVRFADGIKELWQDPNRILLEVGPRTTAATLARKQAKDLKKQVAISSLSDNNENQSEWTALLSAIGQLWLCGVSIDWQSFYQEETRDRLPLPTYPFESKRFWIEPKKGGEWESGRGGEGENSQFPMPNSPLPMPNSPLPIPKNQQSTVNSQQSTVNNQLPMPNSQVETKQAARKYRLIPVIKNILEETSGEDLASVDEDLTFLEMGLDSLSLTQVALNLQKEFSIKITFRQLLETFPTLGTLSEFIDGALPPEVLPATPAVQQAAPVPAPAAAIAPPEQTAIPVPASAPINLPLPSLQPAIAIPVQSGNLEYLIGQQLQIMSRQLELLGGAGLVPAQPAVGEQSRTTQTTNGRDSAPVPAPSQPPAPVQKYVIEEAPSQTNGSAIAPKAEPKAAPTAEPKKVFGAAARIDTSDRDGLTPQQSAYLETFVKRYTARTQKSKQYTQTHRHHLADPRVVSGFNRTMKELVYPIVVGRSSGSKLWDEDGNEYVDLTNGFGSNFFGYSPAFITEAIAAQMQRGYEIGPQTPLAGEVAELVCEMTKHDRAAFCNTGSEAVLGAMRLARTVTGNSTIVMFTGDYHGIFDEVIVRGTKKLRSLPAAPGIPQSAVDNTLILDYGEPESLEILKARAGEFAAIMVEPVQSRRPDWQPREFLHEVRRISDRAGCAFIMDEVITGFRVAPGGAQEYFGVQADIGTYGKVVGGGMSIGVIAGKSAWMDALDGGFWQFGDDSFPEVGVTYFAGTFVRHPLTLAAAKASLEYLKRGGPSLQRDLNAKTDKLVAELNAMFDRSQAPFTVKNFGSLFKITYPQDFPYGELLFYSLREKGIHIWDHRPCFLTLAHSDADIAFVKEAFKQSIVELQSAGFLPDPSGGTFKVLDFNKNGNTNGSKSSTAFANNSPVPGAKLGRDPNGNPAWYIADPERPGKHLQVGDSLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0A5</accession>
    <name>A0A2G4F0A5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55183">
        <property type="protein sequence ID" value="PHX55183"/>
        <property type="gene ID" value="CP500_012435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="24"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="287" mass="32204" checksum="58661B783B95DF65" modified="2018-01-31" version="1">MATIDILGVRHAYDLTAPRTTPHVLVFVHGWLLSRHYWQPTIARLADNYQCLTYDLRGFGDSIAYDDTRGLSEPLNSSYTPAAYARDLAILLEKLDISSAWLVGHSLGGTIALWGASQSSDRIKGVLCVNAGGGIYLKEEFERFRAVGKQLVKLRPLWLSYLPFLDFVFARDSVAHSIGRSWGRQRLIDFVAARSEAATGTLLESTTEAEIHRLPQIVSQLKQPVYFIAGTKDKIMEPKYVLHLASFHWMFQGCGENVLQIPDCGHLAMLEQPDAVVNYLTKILHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0F6</accession>
    <name>A0A2G4F0F6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55240">
        <property type="protein sequence ID" value="PHX55240"/>
        <property type="gene ID" value="CP500_011890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013572613" evidence="1">
        <location>
            <begin position="30"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="35"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="20325" checksum="B9D68B0BA8D35EB8" modified="2018-01-31" version="1">MLSRRYFFSTLLAICLVIFSFNLAAPAFALGGKLPQVNQAAPEFTLPTNSGNGQVSLSDFRGQWLVVYFYPKDFTSGCTIEARRFQQDLPKYLAKNTQILGISADDVNSHAEFCDSEGLKFPLLADTDGKVSKAYGSWMSFISARHSFIIDPKGVLRETFVKVNPAIHSKEVFSRLQELQANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0L3</accession>
    <name>A0A2G4F0L3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55296">
        <property type="protein sequence ID" value="PHX55296"/>
        <property type="gene ID" value="CP500_011675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="90" mass="9697" checksum="9C2D58B28B016CCC" modified="2018-01-31" version="1">MPIPQKNRNLVEQAGEPVADGQDAHPQKNRTLVEQASCLLRASCLLLTGRMPIPQKNRTLVEQAGEPVAETVPLDATSPPTLDKSSEAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0M8</accession>
    <name>A0A2G4F0M8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sporulation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55288">
        <property type="protein sequence ID" value="PHX55288"/>
        <property type="gene ID" value="CP500_011620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013486">
        <property type="entry name" value="SpoIID/LytB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013693">
        <property type="entry name" value="SpoIID/LytB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30032:SF4">
        <property type="entry name" value="PTHR30032:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08486">
        <property type="entry name" value="SpoIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02669">
        <property type="entry name" value="SpoIID_LytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoIID" evidence="1">
        <location>
            <begin position="123"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="42573" checksum="03B85F829B4A6A12" modified="2018-01-31" version="1">MQPRVFFASVLSILGKRYFWISLVFSLAMVAPAQAALILRVAVQEGASQLRVGSSTKAAIRDGSGRNLGELTGNSAQSAQLRSGKVAIGSWAANQIWIEPVGNGYVWIGDRWYRGRTLLIPQKSGLTAVNYVDIEQYLYSVLGAEMSGNWPQEALKAQAVAARSYAIHQRLKSETDIYDVDNTQSSQVYKGLQTESSGTYAAVDATAGQVLTYNSQIILAVFHSASGGHTENVEDVWTEPLPYLRAVPDFDQGAPVYQWKESFTRTQISNKISGVGNVISMKPERTTRHGSVLTMKVVGDGGSRVMSGADLRRVLNLRSTRFTVIPQYGIFSGRNGDKPPTGFEVAGKGFGHAVGMSQWGAYNLARQGYGYQQILLHYYRGTSLARIAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0N3</accession>
    <name>A0A2G4F0N3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type I restriction endonuclease subunit S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_012950</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245905">
        <property type="entry name" value="S.Tbo703ORF12955P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55017">
        <property type="protein sequence ID" value="PHX55017"/>
        <property type="gene ID" value="CP500_012950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="7"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="227"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="524" mass="59387" checksum="7A877462E6C8A2DB" modified="2018-01-31" version="1">MSKQPPGWVTATLADVTEYISRGKSPKYTHHSSLPVVNQRAIRWFGIQQEHLKYIDPAQFDLWTPERFIRIGDILWNSTGTGTMGRACLVTQRDVKQPKVVDSHVTIVRPNQSAIEPRFLFFWIQSPEIQDNISSFATGTTNQIELSRLAIASIQIPIAPLNEQKRIADKLDALLARVDSCRKRLDRISLILKRFRQSVLAAATSGQLTEDWRDIYSTNKMARWVSLEDVASKLSYGSSAKSSPSGSVPVLRMGNIQDAKLDWNNLVFTSDIKEIEKYQLLTGDVLFNRTNSPELVGKTAVYKGERPAIYAGYLIRVRCSADLLPDYLNYCLNSPAGRDYCWQVKSDAISQSNINARKLAAFQFELPPIEEQAEIVRRTEVLFAYADRLEARYQAARTQVDRLTPTLLAKAFCGELVPQDPNDEPASVLLERIRAERAAQPAKPKRTQASRKPTITKMTEESVKEAISQLPKDKFSFDELRENIPGNYDLLKDILFALLSEDEPSLKQVFDREEQTMRFVRAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0P6</accession>
    <name>A0A2G4F0P6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Folate/biopterin family MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_011350</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55333">
        <property type="protein sequence ID" value="PHX55333"/>
        <property type="gene ID" value="CP500_011350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004324">
        <property type="entry name" value="FBT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="PTHR31585"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00788">
        <property type="entry name" value="fbt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="484" mass="52946" checksum="F7F3B8B43EC49404" modified="2018-01-31" version="1">MLVSPSGVSKLKESLKEKVFFGNEPTPELIAILLIYFVQGILGLARLAVSFFLKDELGMSPAEVSVTLGVVAIPWMIKPLFGFMSDGLPIFGYRRRPYIFLSGLLGTSAWVGLATIVHTPLAATGAIALSSLSLAVSDVIADSLIVERARKESVTDAGSLQSLSWGVSALGGLITAYLSGSLLQHFSTHTIFLITASFPLIISATAWLITEEKINKRTDFETVKDQLKQLRQAVTQKTIWLPTAFLFLWLATPTSDSAFFFFTTNELGFQPEFLGRVRLVTSLAALAGILLFQRFLKTIPFRVIFAWSTVTATALGLTTLLLVTHANRALGIDDQWFSIGDSLILTVVGQIAYMPVLVLSARLCPRGVEATLFAVLMSITNLSEIISYEGGAIITHWLGITDRNFDNLWLLVLITNLSTLLPLPFLNWLPADSTESGVPNYQQSLPVLEPELGFSKPGGQHFMPEYFPDLVPTVISENRTVDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Q1</accession>
    <name>A0A2G4F0Q1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNB domain-containing ribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55326">
        <property type="protein sequence ID" value="PHX55326"/>
        <property type="gene ID" value="CP500_011310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="1">
        <location>
            <begin position="265"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="668" mass="75864" checksum="26B75948C71E9D11" modified="2018-01-31" version="1">MDKGTLVEFRLHGDRRLAVADRPDGKKNWVLVDENSQPHSIPPKQITYEIAGETYKPSDIPKFLKEVEVYSDPSSLEVAWELLVDGGETADPESLAVLLFSDRTAAQCYAAYFLLSTDKLYFKQKGDRYEPRSIAQVAEIKHQQEVEQQRHQESQGFWDRVKQRLAGKNVEWANSDRTRLDALERFATLGEEATHRTPALETLASLERSETPEAAFQLLVDLGLWSHHENLFLRRSQIPLQLPAKVLEEVQRCLENLPSDSDTNRLDLTHLKVYTIDDESTTEIDDGLSLEFLENGQQRLWIHIADPTRLLSPGDELDMEARKRTTTVYLPTGMIPMFPPELATGPMSLIQGKECSALSFSVILDETGAAQDYSIHISTVKPTYRLTYDDVDEMLELGIEAEPEISAIATLAKLRQKWRETQGAISIFMPESVIKVNGEEIKIHVIDDSTARLLVAEMMILAGEVAARYGQTHSLAIPYRHQPQPELPPEEELLAVPAGPARACAVRRCMPRSEMNLTPGRHSSLGLEAYTQVTSPIRRYTDLLTHFQIKAHLRDEPQPFSPEEMQDIVMCLGTAVREASSVERQTNRYWGLEYLRRNPDEVWEALMLRWLREDSNLGLILLEELGLELAMRFGRSVEIGDRFEVKVTHCDPRSDVIQFQEVILQAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0V9</accession>
    <name>A0A2G4F0V9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55414">
        <property type="protein sequence ID" value="PHX55414"/>
        <property type="gene ID" value="CP500_011120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="255" mass="29464" checksum="118F15A01A49A355" modified="2018-01-31" version="1">MIEFVVIVESSADARTATKLADRVLVDKIDWLDPEMLQHLFQWSGLESGTENSCWKNIDDITKRLSDKFKFPTIRSNGKFKSDGQSANKIMKLVSFLQHKQKRDIKAVIFMRDLDNQPQRREGIEQARLENIDRQHKLAIIIGTADRMREAWVLNGFVPSNQEEAQILKEITTELTFNPCEESHRLRSNSLTEPDRIRNPKIVVEKLTGGKMEREQQCWEDTDLEILRKKGVQTGLTAYIDEIEERLIPIIGSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0X1</accession>
    <name>A0A2G4F0X1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55395">
        <property type="protein sequence ID" value="PHX55395"/>
        <property type="gene ID" value="CP500_011010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="8482" checksum="861B9EFC36A88801" modified="2018-01-31" version="1">MLPVRKKLVTDEAMRPVAVLIDYEDWQKIEQLLETLIIHKKENSNLAKYAGVIKLTEDPLDYQRQIREEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F146</accession>
    <name>A0A2G4F146_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55479">
        <property type="protein sequence ID" value="PHX55479"/>
        <property type="gene ID" value="CP500_010680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="606" mass="67135" checksum="BEC564DD7D137913" modified="2018-01-31" version="1">MKINPQYVLISASVLGIMIPASYILYLISQAGDLSNFDYWWMTWNFYSVDGFSTNPFNWIFRANEHFVLIPAIIYALNIVITQGSNIGLCLTGWFLALIQCHVLIALLPLKLRHFPLQFILVVVGISIFNFTPAAAHNWMRGFSGVHWIIANLFVICSIFCLQFYAKNLSVGAVPPFPPSSLDISHNSCGTGILPVQNRLFRRCLLQNKWVIGSIIFGILGCISYSTPLALWPILCAAAVILRFPRQVTYLYFGTSIAVIGTYFLTYKTPTHHPSLTKINPLKTLEYIPTYLGGIFSENVIIASIIGIIGLIAVTGFVGYWLFGKKSDRAEWLPWLSIQIYTLQTALMAAVSRSGFGVEQATASRYGTLPALFWMSTFVLTVLCVRQLQPTPRMQTRWLTPLLGIATVAVILMYGVGGETASAIARRATYQPLVALSLQLGITDVTLIKEKIGNRPAAFIGLIDALQTHNLVPFNRDVKKHNFCAALDTKIDSNLLSVPKDGVPGYFDIVTKLAPSAARVIGWVGDPENNVKCIAILNQENVVRGFAMSGFPRPDLVNLFGPGYKSAAWRGYIQTSPTDKLLTAYASFKNREGWIALRNSQTINNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F173</accession>
    <name>A0A2G4F173_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">4-diphosphocytidyl-2C-methyl-D-erythritol synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">MEP cytidylyltransferase</fullName>
            <shortName evidence="7">MCT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ispD</name>
        <name evidence="8" type="ORF">CP500_010290</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) = 4-CDP-2-C-methyl-D-erythritol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="EC" id="2.7.7.60"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.60" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55488">
        <property type="protein sequence ID" value="PHX55488"/>
        <property type="gene ID" value="CP500_010290"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02516">
        <property type="entry name" value="CDP-ME_synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00108">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001228">
        <property type="entry name" value="IspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018294">
        <property type="entry name" value="ISPD_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00453">
        <property type="entry name" value="ispD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01295">
        <property type="entry name" value="ISPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="7">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="7">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="230" mass="25543" checksum="1B8AB9FA2B3B63D2" modified="2018-01-31" version="1">MHLLIPAAGSGRRMGSQRNKLLLTLLLKPLLSWTLAAAEASQHITWIGIMGQRSDFPDFEAIIRDLCPKKPIELIEGGVTRQESVYNGLQALPPDADRVLIHDGARCLATAELFDRAAEALLSCPGLIVAVPVKDTIKVVDEHRIVRETPERRNLWAAQTPQGFEVKLLKQCHQQGREKGWEVTDDAALFEKCGLPVQIVEGEETNLKVTTPVDLALAEFILRQRTDKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F181</accession>
    <name>A0A2G4F181_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase subunit sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_010345</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55498">
        <property type="protein sequence ID" value="PHX55498"/>
        <property type="gene ID" value="CP500_010345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="34"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="139"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="197" mass="22989" checksum="A43DE005EE177F06" modified="2018-01-31" version="1">MLGVLANVLIDDCSDSDLVAECLKGDDRTCFRHLYQRYQHKVRSTLYQLCGSSLLDDLTQEVFLRVWKGLPKLKQQDNFSTWLYRITWNVAYDQRKTFAKQHSFDSKLKTQAEMNQVVTKDHTSDLMQLHYQDLVQRGLEQLSFEHRSVLVLHDLEDIPQKEVAQILGLPAGTVKSRVFYARNAVRQFLQKEGVREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F182</accession>
    <name>A0A2G4F182_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Long-chain acyl-[acyl-carrier-protein] reductase</fullName>
            <shortName evidence="1">AAR</shortName>
            <ecNumber evidence="1">1.2.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADP-dependent reduction of long-chain acyl-ACP to the corresponding fatty aldehyde. Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane, by producing the fatty aldehydes used by aldehyde decarbonylase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a long-chain fatty aldehyde + holo-[ACP] + NAD(+) = a long-chain fatty acyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:12682"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17176"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:133243"/>
            <dbReference type="EC" id="1.2.1.80"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a long-chain fatty aldehyde + holo-[ACP] + NADP(+) = a long-chain fatty acyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:54176"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:12682"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17176"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:133243"/>
            <dbReference type="EC" id="1.2.1.80"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.80" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55534">
        <property type="protein sequence ID" value="PHX55534"/>
        <property type="gene ID" value="CP500_010550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016836">
        <property type="entry name" value="AAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026396">
        <property type="entry name" value="UCP026396_short-chain_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04058">
        <property type="entry name" value="AcACP_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_DH" evidence="2">
        <location>
            <begin position="146"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR026396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="340" mass="37864" checksum="24EED4C315B47693" modified="2018-01-31" version="1">MFGLIGHLTSLEHAQSVANELGYPEYADQGLDFWCSAPPQIVDHITVTSITGQKIEGRYVESCFLPEMLATRRIKAATRKIINAMAHAQKNGINITALGGFSSIIFETFNLQQIKQIRNLKLEFERFTTGNTHTAYILCRQVEQAAPKLGIELSKATVAVCGATGDIGSAVCRWLNAKTNVAELLLIARDKERLQNLQTELGRGKIMGLEEALPQADIVVWVASMPKGVEIDPSTLKQPCLLIDGGYPKNLATQVQHPEIYVLNGGIVEHSLDIEWKIMKIVNMDVPGRQLFACFAESMLLEFEKLYTNFSWGRNQITVEKMEQIGEISVKHGFRPLMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F192</accession>
    <name>A0A2G4F192_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55522">
        <property type="protein sequence ID" value="PHX55522"/>
        <property type="gene ID" value="CP500_010470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="10568" checksum="35E2854675F1B334" modified="2018-01-31" version="1">MIISDLNYLESAEANVEGGYYFGPSSSTNVYADIRENLTINKVFNSVTKTQGTFAGAEATASALGANSATQAISNTVTIQGVGSTSNATSISGSNGNPVWHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F199</accession>
    <name>A0A2G4F199_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">folE</name>
        <name evidence="8" type="ORF">CP500_010535</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55541">
        <property type="protein sequence ID" value="PHX55541"/>
        <property type="gene ID" value="CP500_010535"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="7">
        <location>
            <begin position="61"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="244" mass="27316" checksum="BF8173856ADDA5EE" modified="2018-01-31" version="1">MTITSNNGSNGSNTLSTDSMKLLETPDKNLPCITTRPDRNSSNGQESSVPIPTEVGQEEMMEAVRTMLLGIGENPEREGLLKTPKRVAEAMRFLTSGYSQSLEELLNGAIFDEGHNEMVLVRDISVFSMCEHHMLPFMGRVHVAYIPNQKVVGLSKLARIVEMYSRRLQVQERLTRQVAEAVQTILEPKGVAVVMEASHMCMTMRGVQKPGSWTVTSAMLGVFQEEQKTREEFLSLIRHQPAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1F2</accession>
    <name>A0A2G4F1F2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55575">
        <property type="protein sequence ID" value="PHX55575"/>
        <property type="gene ID" value="CP500_010115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="290" mass="32268" checksum="5AC7627AD98A2F0A" modified="2018-01-31" version="1">MSDFKKSKKAADSKRKTQGDVSDSSNLEVLVEDIEQADQEVDEQIQIIKTKTEELENLGQKLKSLPEKLGELEGEALQVAYQEINQKMEQKATEIDESRGKLETIKEDMQQKQSEITEQIAKRDEALTELEEAERECDADLSESKDAVNDEKDNLEDVQNKVGEILKKIDAAGETMKKVDTTISNAQSKANNIFSKIGDISKKFAAGVVTFTGIASGLADVNNRVAAPLFPNDSVFSQIKDRSNKAEDYHSLNSDAIDLDSSNESEKERRKRESEESSELGNESEKSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1F9</accession>
    <name>A0A2G4F1F9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="6">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaD</name>
        <name evidence="9" type="ORF">CP500_009910</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial CoaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55586">
        <property type="protein sequence ID" value="PHX55586"/>
        <property type="gene ID" value="CP500_009910"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="8">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="164"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="8"/>
            <end position="9"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="87"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="122"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="192" mass="21399" checksum="EE587A3111C8062F" modified="2018-01-31" version="1">MIAIYPGSFDPITFGHVDIIERGCKLFDRVIVTIVRNPSKVPLFTVEERIEQILCSTKHLSNVEVDSFEGLTVNYAKMRQAKVLLRGLRVLTDFEMELQMAHTNKTLLGEIETVFLATSNAYSFLSSSVVKEIAKFGGSVDHLVPKHVALDIYKCYASRNPLASNPTPPDAALRTNYLSTQPPSETTPEPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1M9</accession>
    <name>A0A2G4F1M9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside triphosphate pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55671">
        <property type="protein sequence ID" value="PHX55671"/>
        <property type="gene ID" value="CP500_009695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011551">
        <property type="entry name" value="NTP_PyrPHydrolase_MazG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30522">
        <property type="entry name" value="PTHR30522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00444">
        <property type="entry name" value="mazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="35"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="182"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="273" mass="30464" checksum="10BF56D006B58E6D" modified="2018-01-31" version="1">MSNSQTRSLTAIQSLIEIVAKLRDPDGGCPWDLAQTPQTLIPHIIEEAYETADAIRRGEKDAIVEELGDLLLQVVLQAQIASESSQFTLAQIADGIAEKLIRRHPHVFGDVEINSVDEVNKNWDKIKAAEKGETGKTPTLAAKMRRYASTLPPIAAGMKISQKAAEASFDWDSVDCVWDKFHEEMAEFEHALKHEDQAAQQSELGDIMFVLIQLSRWYGLDASEALQGTNQRFVERFALVEGKCDRPLSDYTPEELDGLWNQAKAMLAQKGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1T9</accession>
    <name>A0A2G4F1T9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3143 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55708">
        <property type="protein sequence ID" value="PHX55708"/>
        <property type="gene ID" value="CP500_009445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021489">
        <property type="entry name" value="DUF3143"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35765">
        <property type="entry name" value="PTHR35765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11341">
        <property type="entry name" value="DUF3143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="90" mass="10489" checksum="82E6698253D58429" modified="2018-01-31" version="1">MTLPSADTPLYNHPLPEIEKWLKSRGCEQNRRELHCWNIDRPAWKAELALEIDQLTIRYINAGNDGQDIERFFKYSLSRQDIEAAVFSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2F4</accession>
    <name>A0A2G4F2F4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sulfur carrier protein ThiS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">thiS</name>
        <name evidence="1" type="ORF">CP500_008115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55929">
        <property type="protein sequence ID" value="PHX55929"/>
        <property type="gene ID" value="CP500_008115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010035">
        <property type="entry name" value="Thi_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34472">
        <property type="entry name" value="PTHR34472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01683">
        <property type="entry name" value="thiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="7767" checksum="18A2CC77134D71D6" modified="2018-01-31" version="1">MTNQIALQVNGETRNCSTETPLPELLKQLGLNPRLVAVEYNGEILHKQFWETTQMQEGDILEVVTIVGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2H7</accession>
    <name>A0A2G4F2H7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="7">HIU hydrolase</shortName>
            <shortName evidence="7">HIUHase</shortName>
            <ecNumber evidence="7">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">uraH</name>
        <name evidence="9" type="ORF">CP500_008210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55945">
        <property type="protein sequence ID" value="PHX55945"/>
        <property type="gene ID" value="CP500_008210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000895">
        <property type="entry name" value="Transthyretin/HIU_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023419">
        <property type="entry name" value="Transthyretin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="PTHR10395"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00189">
        <property type="entry name" value="TRNSTHYRETIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="SSF49472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00769">
        <property type="entry name" value="TRANSTHYRETIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TR_THY" evidence="8">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600895-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="120" mass="12829" checksum="7E714F91CFDA3B61" modified="2018-01-31" version="1">MSGKLTTHVLDTARGCAAANMSIALQSIDPKSGAKTLLKTVTTNADGRTADPLLSDSELKPGVYELVFSVGEYFAQSAENLPEPPFLNSVPIQFGIADITAHYHVPLLVSPWSYSTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2I4</accession>
    <name>A0A2G4F2I4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elp3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55984">
        <property type="protein sequence ID" value="PHX55984"/>
        <property type="gene ID" value="CP500_007795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Elp3" evidence="1">
        <location>
            <begin position="235"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="677" mass="78512" checksum="603B31DEDCCC4407" modified="2018-01-31" version="1">MLPTYTGIRPPKPVDILFLNLSNLPGRPVYPYAFVQVSALARRVGLSVVRWDGLDLSRQQKLECITQLVKDHQPRAVAFTIRQADSVAADNYISIDSKTPAQNPWFPVEDTRAAILRVRELSDAKIFVGGFNFTVNSVSAAEYLQPDFGILGEPDEFFDHFDEVLMGRTEGISNLLYRADGEWRQNQRVYWGPLDEIEYTEDIIDEIFRFHGERNLRNANLEDVPGLGSYKETGISIAVEIARGCPCSCVFCCEPKVKGKTVRVRNLDVIEAEIHNLLRYGLRYYWFICSELNFAKEHVLELAERVIKINETLARPIFWRAYFLPGTFSKDEFRILLRSGLLIEQSGAFTTLSNENLKQMREPYRVRHALQHIKDLMELNEEPEFQDRRQPRWILWSWLGNPYATLDSVRTTLETFSQEKLDLKYDEADTYPALRVYECLDNLPEEARQEAITVTQDDDTPKTLIHPSYYYNSKLIEHFEGIGEIHDFMQYARETFLSRYYRLTRNWRLFAQNLEFPLLEEVVTPLKDADLGVIQLPPWVEHPDLGKLNPIYWQEQANILLHQESSTLKQLIKEAETKQDEENAILAFILHAAFSVSRQEMAPVFEKLKLPMDSEGYPPASSYLTFSTLIQLHNTEASVLEAVKQDFTPKQLILFRYYLYAINVRLKPKYAFLAPKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2J1</accession>
    <name>A0A2G4F2J1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hybrid sensor histidine kinase/response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_007855</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55993">
        <property type="protein sequence ID" value="PHX55993"/>
        <property type="gene ID" value="CP500_007855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="143"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="362" mass="40307" checksum="0E16E801EFBCF8F0" modified="2018-01-31" version="1">MAKILVIEDEEAIRENILELLAAENFESIGAANGKLGINMAIAQIPDLILCDMMMPEIDGHGVLKALRSEPITATIPFIFLTAKADKTDIRLGMELGADDYITKPCTPQELLKAVVIRLDKHKAISKKSQKTLDELRSNISMSLPHELRTPLNAIMGFSELILSEYSILQESEILEMIGYIQLSGHRLYRLIQNFLLYTDLEMAATNPKLLKEMQNSEFRCVESLLSEKARQQAKQANRLDDLHLNLQDSSVAIDSIKLTKILEELLDNAFKFSSEGSPVLVSAFVENQRFILSVKDQGRGMTAAQIAQLEAYMQFDRQLYQQAGLGLGLAIVKRITELHGGSLKIECSTDKSTIVSVCLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2J6</accession>
    <name>A0A2G4F2J6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Glutamate synthase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CP500_007935</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55968">
        <property type="protein sequence ID" value="PHX55968"/>
        <property type="gene ID" value="CP500_007935"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015930">
        <property type="term" value="F:glutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="16">
        <location>
            <begin position="33"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="879"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="884"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX55968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1610" mass="174556" checksum="77B536E0B846C70E" modified="2018-01-31" version="1">MGNTSDRNQNQNQSHRGIPYAGQSWLIEERDACGVGFIANQNGAATHSLIEKALPALTCLEHRGGCSADQDSGDGAGLMTAIPWELFHSWFAEQGIQPPAQEKCGVGMLFLSRDENQAAIARHMVEEILLERGLTLLGWRKVPVDASVLGPQALENQPQIEQVIVSSPQLQGDELDRQLFLARRAIGHALSHRPDFTRQDFYSCSLSSRTIVYKGMLRSAVLGEFYLDLKNPAYKSAFAVYHRRFSTNTMPRWHLAQPMRLLGHNGEINTLLGNITWMKARQANLAHPNWSQADLNTFNPIVNSESSDSANLDNVMELLVHSGRSPLESLTILVPEAYKNQPDLAPYPEIVDFYEYYSAIQEPWDGPALLVFSDGKQVGATLDRNGLRPARYCITKDGLVIVASEAGVVDIDEADIVEKGRLGPGQMIAVDLQTQEILKNWQLKQRIAKRHPYGEWLQKNRETLEPQPFAETATLDSQTLLASQIAFGYTAEDLDMVIVEMASSGKEPTFCMGDDIPLAVLSEKPQLLYNYFKQRFAQVTNPPIDPLREGMVMSLTVNIGLRGNLLQAVPENAKLLKIDSPVLNDAELSFLKEQKSFPAEVLSTVYKIDGGPEGLKSAVAQLCQKAADSVRSGAKILILSDRVAKEEGSSATDFVTDVTDVKKKEEGDEISSVGLSAESTYIPPFLAIGAVHHHLIQEGLRMQTSLIVDTAQCWSTHHFACLIGYGAAAVCPYLALESVRAWWADSKTQNLMKHGKVPNITVTEAQAKYRKAVENGLLKIMSKMGISMLSSYQAAQIFEAIGIGGDLLDLGFKGTVSRIGGLTVAELGQEVMSFHSQAFPELNAKKLENYGFVQYRRGGEYHMNSPEMAKALHQAVRANGHSPLQDQEGRREEGSKGGNSENVAEPKMTPIGDKNSETAYDHYEVYKKQLETRPVTALRDLVDFASDRPSIPIEEVESVADVVKRFATGGMSLGALSPEAHETLAIAMNRIGGKSNSGEGGEDPKRYNVLNDVSEAGFSQTLPHLKGLQNGDTASSAIKQVASGRFGVTPEYLMSAQQIEIKVAQGAKPGEGGQLPGPKVSEYIAYLRRSKPGVTLISPPPHHDIYSIEDLAQLIFDLHQINPKAGVSVKLVSEVGIGTVAAGVAKANADVIQISGHDGGTGASPLSSIKHAGSPWELGLTEVHRVLMENKLRDRVLLRVDGGFKTGWDVIVGALMGAEEYGFGTVAMIAEGCIMARVCHMNTCPVGVTTQKEELRKRFPGTPEHVVNFFYFVAQEVRSLLAKLGYKSIADIIGRGDLLTMRAGVKLTKTQGINLDCLTKLPDTKTDRTFLIHGDVHTNGPVLDDDLLADAEIQSAIANQTSVSKSVKLVNTDRTVGARISGAIAKQYGNTGFTGQITLNFTGTAGQSFGAFNLPGMTLVLDGQANDYVGKGMHGGEIIIKPPADATYDASENAIVGNTCLYGATGGILLAAGKAGERFAVRNSMAKAVIEGAGDHCCEYMTGGVIVVLGKVGRNVGAGMTGGLGYFLDEDGNFPAHVNGEIVKMQRVCTAAGEAQLKELIEAQRDRTNSKKAEKILANWAEYLPKFWQVVPPSEANSPEASEQKIAVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2K7</accession>
    <name>A0A2G4F2K7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hybrid sensor histidine kinase/response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_007840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55990">
        <property type="protein sequence ID" value="PHX55990"/>
        <property type="gene ID" value="CP500_007840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="11"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="172"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="477" mass="53475" checksum="570A1677FA067D4B" modified="2018-01-31" version="1">MNNDINTDRGNILVVDDTPANLRLLAGILNGKGYKVRPVPNGELALSAARGMPPDLILLDIMMPEMNGYEVCEKIKADERTRDIPVIFISAINDVLDKVKAFAVGGVDYITKPFQMEEVLVRVETHLAMCHLQNKLKQKNEELTLTLEQLKETQNHLVQSEKMAALGQLIAGIAHEINTPLGAIRSSIGNITNFLDNNLETLPVFFKEMSTERQQDFVNLMHSSNQQDYSLSTREKREFKRGVKQQLELQQIGNADSLASILVNIGLQTDLQSFLPLLKDPDSEKILKTAYEFSSIQRSARTIATATERAAKVVFALKNYARYDFNAEKSEMNIVEGIETVLTLYQNQLKHGVEVVRNYQSQVPTILCYPDELHQVWTNLVHNSLQAMENKGVLRIDIVQQDRWLQVSITDSGKGIASEILPKIFEPFFTTKSMGEGSGLGLDIVRKIIEKHEGKIDVNSMPGQTTFTVSLPINLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2L9</accession>
    <name>A0A2G4F2L9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_007850</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55992">
        <property type="protein sequence ID" value="PHX55992"/>
        <property type="gene ID" value="CP500_007850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="168"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="247"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="300"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="375"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="449"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="521"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="7">
        <location>
            <begin position="630"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="867" mass="98306" checksum="4FEA3539F8188E93" modified="2018-01-31" version="1">MKKPVIICVDDEPTILDSLEIDLLKAFEDKYLIETAESGEEALELLSDLLAENYEVPLIISDHIMPNMKGDELLRNVHAVSPKSLTIMLTGQADLSAVTNAINYAKLYRYIAKPWQADDLKLTVTEAIYRYFQDKQLAEKQVELQEMNQELAKLSRKQANLIAKLHENESRLTQYLEAMPLGVCVLDASGQSFYANQKAREIFGRGTVPHINSEQKAAIYQFYKSGTNQRCPVEELPIMRALRGESLRTESVEIRAGNKIVPVESWATPIYDSVGEISCGIIAFTDITERKEVEAALIQAEEKYRGIFENALEGIFQTTPDGQFISANPALSQIYGYDSPEELIESVNNIEHQLYVEPQRRQEFMALIKQHGTVSDFESEVYCRDGSVIWISEYARAVYDASGEVLYYQGFAKDITLRKEVEMERLRFTNDLEKALLAEEKLNEALLENESRLTQFLEAMPVGIFVVDGKGTPFYINSCGERILSQGLISDVANDKLPEVYQFYSADTNELYPIDRQPMIRALRGEVVRVDDAEIHGADWIVPIEVWATPIYNEAKNIVYAIAAFQDITERQQVDRERRQFTDELEKALAAEEKLTDAYGRFVPHQFLHFLGYESILEVRLGDQIQKEMSVLFSDIRDFTALSETMTPQETFKFINTYLSRMEPVIAENQGFIDKYIGDAIMALFDGSADNAVKAGIAMLEQLNEYNATHTQPDRPLLQIGIGINTGSLMLGTVGGQNRMDSTVISDAVNLASRVENLTKEYGVSMLITHNTFIQLEEVYDLRLLDRVKVKGKSQMVTVYEVFAADLPELRQKKSETKTIFEQGLVFYHANRFIEATILFSACLQQNPADNVAQIYMQRCLKQTLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2R8</accession>
    <name>A0A2G4F2R8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Transaldolase</fullName>
            <ecNumber evidence="6 7">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">tal</name>
        <name evidence="8" type="ORF">CP500_007760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 7">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the transaldolase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="6 7"/>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56038">
        <property type="protein sequence ID" value="PHX56038"/>
        <property type="gene ID" value="CP500_007760"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00955">
        <property type="entry name" value="Transaldolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00493">
        <property type="entry name" value="Transaldolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004732">
        <property type="entry name" value="Transaldolase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036915">
        <property type="entry name" value="Trnald_Bac_Plnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00876">
        <property type="entry name" value="tal_mycobact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0704">Schiff base</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="7">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="384" mass="42127" checksum="EA8744D14F8288C3" modified="2018-01-31" version="1">MTEATKNHLLEIKEIGQSIWMDNLTRNLIESGELKKMIESRGLRGITSNPAIFEKAIAGNVIYDADIEAGIRAGKSVLEIYESLVFEDIRNACDIFAPVYAESNGLDGYISIEVPPTIANDTESTISEALRYYQAIGKPNVMIKIPGTVQGLPAVERVISEGINVNVTLLFSVDSYVETFWAYIRGLEARAAKGLDVSNIASVASFFLSRIDINIDGQIDEKLKGVTDVATKAKLEAVKGKIAIANAKVAYQKYKEIVASDRWQALAAKGAEVQRLLWASTSTKNPNYSDVMYVDELIGPDTVNTLPPNTVEACFDHCDVAPRIENNVEEAYALIESLKDPDIDIDLDQVMADLLLEGIEKFVSPFQSLMDSLAEKVQKLSPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F305</accession>
    <name>A0A2G4F305_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-1-phosphate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rfbF</name>
        <name evidence="2" type="ORF">CP500_007075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56140">
        <property type="protein sequence ID" value="PHX56140"/>
        <property type="gene ID" value="CP500_007075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047343">
        <property type="term" value="F:glucose-1-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02524">
        <property type="entry name" value="G1P_cytidylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013446">
        <property type="entry name" value="G1P_cyt_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02623">
        <property type="entry name" value="G1P_cyt_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="258" mass="29728" checksum="799EBEFFAEAB5A5A" modified="2018-01-31" version="1">MQVVILAGGLGTRLREETEFRPKPLVDVGGRPILWHIMKTYAHYGFHDFIVCLGYKGNMIKEYFLNYEAMNNDFTICLGRQNQITYHEEHQEQDFKVTLAETGPDSMTGGRVKRVEKYITDDTFMVTYGDGVADIDIGALLDFHKSHGKLATVTTVRPISRYGILDVDNQGQVLEFTEKPQIDGWASAGFLVLHRSIFEALSGDDCFLEREPLERLAAEGQLMAYRHEGFFFAMDTYREYKYLNELWDNGEAPWRVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3D5</accession>
    <name>A0A2G4F3D5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3110 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56293">
        <property type="protein sequence ID" value="PHX56293"/>
        <property type="gene ID" value="CP500_006055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021503">
        <property type="entry name" value="DUF3110"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11360">
        <property type="entry name" value="DUF3110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="14005" checksum="F77D1AE05136F296" modified="2018-01-31" version="1">MRVFVLLFNARTENEGIHTIQLGDRNKVLMFESEDDAIRFGLMLEAQDFPEPTVEAIDEEEIKEFCDSVHYDWELVPAGALEIPPANNVTQIEWQSQPEPKSDTDVSQSELDSIRRRLEGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3E0</accession>
    <name>A0A2G4F3E0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF268 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56266">
        <property type="protein sequence ID" value="PHX56266"/>
        <property type="gene ID" value="CP500_006265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004951">
        <property type="entry name" value="DUF268_CAE_spp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03269">
        <property type="entry name" value="DUF268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="442" mass="49976" checksum="9D8CC5D7AF9AF836" modified="2018-01-31" version="1">MISDLEKMFDAFASSRSVNINAPQIQKYKQDFIDYFTRFNESEESKEFPNTIFYPCLGDDLPNTPIDKYYLYQDTWASRKIFEQKPSAVVDIGSTVLYASIISQFVPTTFVDIRPPEINLPGLKLVAGSILDLPFEDASQSFVTSLCVVEHIGLGRYGDPIMPNGTRRACAEIDRILKPGGELIVSVPLGTSCIAFNAHRIFSKQQFLSYFPGYQILDEVYLAPHPSGADVLKSLKVGEMCVYVVHLKKIQNKSELEVQYWIASGKPVPPPPAIKQQVVKDYAQRFSLTTLVETGTYLGDMVFSMRDVFRQIFSIELSVPLYLEAKERFSSRPHIYILQGDSAQVLPKTLTYLNEPCLFWLDGHYSAGITAKGDLETPIMQELEAILSHPIKNHVILIDDAREFTGMNDYPTVSQLKEFVAKSRPDYQVDLENDILRIHQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3E5</accession>
    <name>A0A2G4F3E5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56282">
        <property type="protein sequence ID" value="PHX56282"/>
        <property type="gene ID" value="CP500_006375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013619607" evidence="2">
        <location>
            <begin position="25"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="7868" checksum="4E747DF8211E4034" modified="2018-01-31" version="1">MKNYTTIALLSLSGLFLSATCAFSIESPVEQVENSTTQYMLSAQTQQRGDSRPIGKGRLSFIQPSAETQPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3G3</accession>
    <name>A0A2G4F3G3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56261">
        <property type="protein sequence ID" value="PHX56261"/>
        <property type="gene ID" value="CP500_006235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="188"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="396" mass="42906" checksum="E51905096C5FE413" modified="2018-01-31" version="1">MLARIQELATTLAPRLIEIRRHIHSHPELSGQEHQTAAYVAGVLASSGVHAIEGIGKTGVIGELKGNSSESRWLAIRTDMDALPIQERTNLEFASKNQGVMHACGHDIHTTVGLGTAMVLSQLEEKLPGHVRFLFQPAEEIAQGARWMIADGAMQDVDGILGVHVFPTIPGGSVGIRHGALTAAADDLELIVMGESGHGARPHEAIDAIWIASQIITTLQQAISRTQNPLRPVVLTIGQISGGRAPNVIADRVKLLGTVRSLHPETHEKLPAWIEQIVASVCQTYGAKYELNYKRGVPGVQNDPKLTQLLEAAALEALGRSRVQILPEPSLGAEDFSMYLEHAPGTMFRLGVGLADKPNYPLHHPQFEVDEAAIITGVVTLAYGACQYWKQHEHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3H2</accession>
    <name>A0A2G4F3H2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56296">
        <property type="protein sequence ID" value="PHX56296"/>
        <property type="gene ID" value="CP500_006075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="12148" checksum="D8C009571806DA47" modified="2018-01-31" version="1">MLSIIYPHIEKVAGQPARLQRIPRVRVAQIVMDYLAYGWSVEEMCRQHPYLMQSEAHATMAYYFDFQAEIEQEIRAEWEQVQQEKSLLSPSPFFVKMRAKGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3I7</accession>
    <name>A0A2G4F3I7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56319">
        <property type="protein sequence ID" value="PHX56319"/>
        <property type="gene ID" value="CP500_006170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="112"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="311" mass="34903" checksum="E6719B319A8402A7" modified="2018-01-31" version="1">MENFKRILRRRKTFIVAFIAALGSFVIGVTLPMNSRGNQQPALSQAQLVTVSESQAKQPKSDVNNLKESIGEKVEFSEKAIDQLQESRFQSTIPSQFEGTTLREAKLDSRQKAIALTFDDGPWPTTTTQVLDILKKNNIKATFFWVGRYLQVYPEIGKQVAAAGHAIGNHTWNHQYIKYNEDDAAREIDRTTSLIEEVTGIKTSMFRPPGGILNNGLVAYAQKKNYTVVMWSADSLDWRTATQSLMENVMRQADSGGIVLMHDGGGNRSKTVEALPDIIAKFRKKGYTFVTVPELLKMQENDLKNQKTAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3J2</accession>
    <name>A0A2G4F3J2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome b6-f complex iron-sulfur subunit</fullName>
            <ecNumber evidence="13">7.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein</fullName>
            <shortName evidence="13">ISP</shortName>
            <shortName evidence="13">RISP</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Rieske iron-sulfur protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">petC</name>
        <name evidence="15" type="ORF">CP500_007390</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>a plastoquinol + 2 H(+)(in) + 2 oxidized [plastocyanin] = a plastoquinone + 4 H(+)(out) + 2 reduced [plastocyanin]</text>
            <dbReference type="Rhea" id="RHEA:22148"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="Rhea" id="RHEA-COMP:10039"/>
            <dbReference type="Rhea" id="RHEA-COMP:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
            <dbReference type="EC" id="7.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="13">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The Rieske iron-sulfur protein is a high potential 2Fe-2S protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.6" evidence="13"/>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56047">
        <property type="protein sequence ID" value="PHX56047"/>
        <property type="gene ID" value="CP500_007390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045158">
        <property type="term" value="F:electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009496">
        <property type="term" value="F:plastoquinol--plastocyanin reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01335">
        <property type="entry name" value="Cytb6_f_Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023960">
        <property type="entry name" value="Cyt_b6_f_Rieske"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="PTHR10134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="14">
        <location>
            <begin position="66"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX56047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="180" mass="18990" checksum="E96999CE67A757CB" modified="2018-01-31" version="1">MAQSSAGNPDVPDMGRRQFMNLLTFGTVTGVALGALYPVVNYFIPPSGGAAGGGVTAKDALGNDIIVSTYLTSHPAGDRTLAQGLKGDPTYIVVEKDSSLAEYGINAVCTHLGCVVPWNNSENKFICPCHGSQYNSEGKVVRGPAPLSLALAHATVADDKIAFTTWKETDFRTGEAPWWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3L2</accession>
    <name>A0A2G4F3L2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56374">
        <property type="protein sequence ID" value="PHX56374"/>
        <property type="gene ID" value="CP500_005895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10493" checksum="FFE5091E36598731" modified="2018-01-31" version="1">MSTQLLMSNNSSTLSRPQITASNPEMASSSNLAIGFTRKVESVKSPYQADHQVKFLHLQAEIESLLLQVQTVKQRRSIAYSQVAIAQNSVDSNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Q5</accession>
    <name>A0A2G4F3Q5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4-hydroxybenzoate solanesyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">4-HB polyprenyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ubiA</name>
        <name evidence="7" type="synonym">plqA</name>
        <name evidence="8" type="ORF">CP500_005600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of plastoquinone-9 (PQ-9) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 4-hydroxy-3-solanesylbenzoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>4-hydroxybenzoate + all-trans-nonaprenyl diphosphate = 4-hydroxy-3-all-trans-nonaprenylbenzoate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:17709"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58391"/>
            <dbReference type="ChEBI" id="CHEBI:84502"/>
            <dbReference type="EC" id="2.5.1.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.39" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56389">
        <property type="protein sequence ID" value="PHX56389"/>
        <property type="gene ID" value="CP500_005600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002083">
        <property type="term" value="F:4-hydroxybenzoate decaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047293">
        <property type="term" value="F:4-hydroxybenzoate nonaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate octaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010236">
        <property type="term" value="P:plastoquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01635">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006370">
        <property type="entry name" value="HB_polyprenyltransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PTHR11048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01474">
        <property type="entry name" value="ubiA_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="294" mass="32210" checksum="8D89BDA1EB0C2108" modified="2018-01-31" version="1">MLTEFDRPTESTLLAIVRLLRWDKPAGRLILMIPALWAVFLAAHGRPSAVLVGVIVLGTLATSAAGCVINDLWDRDIDPEVERTRSRPLASRALKVQTAIGVALISFACAAILAFYLNPLSFWLCVAAVPVIICYPLAKRFFPVPQLVLSIAWGFAVLIGWSATVGKLELATWLLWGAVVLWTLGFDTVYAMSDREDDLRLGVNSSAIFFGDNAANAVGFFFVATVGLLAAIGINLHLHIGFWIAILGAAILWFLQYSQLRNADIHRPVYGQIFRQNVWVGFVILAGMIVGEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3T6</accession>
    <name>A0A2G4F3T6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56443">
        <property type="protein sequence ID" value="PHX56443"/>
        <property type="gene ID" value="CP500_005425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013653">
        <property type="entry name" value="FR47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08445">
        <property type="entry name" value="FR47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="176" mass="19780" checksum="F89CBC73B6E49B6B" modified="2018-01-31" version="1">MVIVRQAKIGDAPAIARVNIDTWRTAYQKIVPADYLAQLSYEKRESNWREILVNAEKNQDFVCVAENEIGQIVGFAAGGYERTDKYIYKGELFAIYILQAYQHQGIGRKLVVTVAAKLAKLNLNSMLVWVLGDNSACRFYEILGGKKVDEHQTNKAGVVVKEIAYGWTDITVSFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3V0</accession>
    <name>A0A2G4F3V0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_005675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56401">
        <property type="protein sequence ID" value="PHX56401"/>
        <property type="gene ID" value="CP500_005675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="5"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="189" mass="21912" checksum="576C9496106B8470" modified="2018-01-31" version="1">MPYRYILFYKPYDVLTQFTDNSGEVKRRTLKDYIPIPDVYAVGRLDRDSEGLLLLTDDGQMQHRLSDPKFAHPRTYWVQVEGIPDAGAIAALQTGVTIQDYRTRSAKVQLLSTEPTLPPREPPIRFRKHIPTAWLEMTLTEGRNRQVRRMTAEVGFPTLRLVRSAIGHLTLESLKPGEWRELSQQDFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3W4</accession>
    <name>A0A2G4F3W4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amino acid adenylation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56425">
        <property type="protein sequence ID" value="PHX56425"/>
        <property type="gene ID" value="CP500_005310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0045">Antibiotic biosynthesis</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="3">
        <location>
            <begin position="575"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="2">
        <location>
            <position position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="925" mass="103266" checksum="EB8F4A3865ABFD10" modified="2018-01-31" version="1">MMNSQDFLTSGDGYLPNKETDALKTTHDVCVDVPLYTHDISSVEDSQVDLTRSHYVSIHQWFEAQVKQTPDAIALSFQGQELTYDALNQRANQLAHYLQALGVQPDELIAICMNRCMEMVICFLGVMKAGAAYVPIDPAYPHERRAYKLRDASVRFILIQQHLVEFLPEHNARVICPDTDWHDMAPYSTENLSLLTTPEHLAYVIYTSGSTGNPKGVMITHRGMVHHSKAIAQEFNLQAGDRVLQFSSMSFDIIIEEVFPSLISGATIVLRTEDSISSTRQFLEFIEQERITILDLPTAFWHGLVSGLSLLGVPMSPDVRLVIVGGEKASRALYAEWRQLVGEYPRWLNTYGPTETTVTATIYDPIAEGYDLSSEADIPIGRPLPNSQIYILDENLNPVPDGDIGELYIGGPGVARGYLNLAERTASKFIANPFSDRPYDKLYRTGDTARYLPNGTLEFIGRIDFQVKIRGFRIELLEIETYLEQYPSVQQGIVLAREDVPGEKRLVAYIIPKHGQPIQLSALRSFLQTKLPAYMIPAAVVVMDSFPMTPNGKVDRRAFPEHQVADLVKNSEVVLPIDGLEAQLVQIWEQILNIKPIGTTDNFMDLGGTSLLAARLADKIDEKLQQSWPLSIIFQAPTIKQLADILRQGNIPNQSLSLVEIQPKGSQPPLFLFEGVSIYHPLIPYLGLDRPIYALIAVVKDGVNGPVNQVEAIADYYIKELVKVQPEGPYYLGGLSFGGIVAFEVAQQLAAKGQETALLVMFDSMLLSAYKPLPIQQRLRFHAQKIAKQGIGYIVSSIVDKIMTLTDKMTMLARKTIGRYLKVKEPTELMSCTTDYLMRDKIIEQAERAYLPKPYAGKVVMFKALDSEDGKSVSLDPDLGWKPYLKDGLTIYDVPGDHLGILQEPNVGAIGNRMKLLLEEVVVLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Y7</accession>
    <name>A0A2G4F3Y7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF502 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56472">
        <property type="protein sequence ID" value="PHX56472"/>
        <property type="gene ID" value="CP500_005110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007462">
        <property type="entry name" value="COV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31876">
        <property type="entry name" value="PTHR31876"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04367">
        <property type="entry name" value="DUF502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="241" mass="26450" checksum="FBAA1A4C9031C635" modified="2018-01-31" version="1">MLQRIKQDLKNDLIAGLLVVIPLATTIWLTITVASWVINFLTKIPKQINPFDGLNPILVNLLNLLVGLAVPLLSITIIGLMARNIFGKWLLDLGERLLQAIPLAGSVYKTLKQLLGTILKSDDKFRRVVLVEYPRRGIWTLAFVTGTIESNDIPPHLSGESPIGIFIPTTPNPTTGWYAIVPEADLVNLSMSIEDAFKVIISGGIVNPSNSAIVTAQNTNGTKFEPLMPDARYHPVPVEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F461</accession>
    <name>A0A2G4F461_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AI-2E family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_004825</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56573">
        <property type="protein sequence ID" value="PHX56573"/>
        <property type="gene ID" value="CP500_004825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="43159" checksum="610E5B44B9554F72" modified="2018-01-31" version="1">MKLGQWIGLLALIASCYILWQIRQALLLLFAAVVLATALNRLARYLQKFRLTRSIAVLLSVSFLILIFVGLFLIVVPPFAQQFQQLTQRAPQGIAKLNEWIDQIETSFSGQIGQRLPNLDINEIIQQLRPIFNQLVGGAGAFVGNTLGVILSFLLVIVLTLMTLAEPQSYRKAFIQLFPSFYRRRVDGILDECEVALGRWVIGALISMSVITFLSLIGLSVLQVPLPLAHAVVAGLLNLIPNIGPGLSVIPPMTIALLDSPLKSGFVLILYFLIQQFESNLLTPYVMAQQVSLLPAVTLISQVFFATFFGFLGLLLALPLTVVAQVWIREVLIKDILNQWHTNPRNLAAIDTAIYEEYEAIGVTQSQPESDPEHKSEISKNTDDPDDSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4A4</accession>
    <name>A0A2G4F4A4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HcyBio domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56576">
        <property type="protein sequence ID" value="PHX56576"/>
        <property type="gene ID" value="CP500_004840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002708">
        <property type="entry name" value="HcyBio"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01837">
        <property type="entry name" value="HcyBio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HcyBio" evidence="1">
        <location>
            <begin position="16"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="391" mass="42727" checksum="60722E55CE90AFFA" modified="2018-01-31" version="1">MRTIDEINDKITQGKATVWTIEELKNRVQETSITQAAKEVDVITTGTFEPMESSGAIINLGHTDPPIKIRQCWLDGVLAYSGFGAVDLYLGATQVAEDGEESRERGGGHVIEDLIAGKPVQLRALGQVTDCYPRASFETTITRDTINQFYLFNPRNAYQNFIVGVNGGDRPLFTYLGPLQPNLGNAVYSSLGAMSPLLNDPDLQLIGIGTRIFLGGAQGYITWEGTQHFPLQKRQPNRTPIGPAATLALIGDAKQMNSKWVRGCYFKNYGPSLMLGVGIPFPVLNETVVANCAVSDQKIVAPVVDFSIPRRVRPTFGLVSYAQLKTGRILIEGKPVRVAPLASMFLSRQVALELKQQIEAGQFTLTAPVAPLPADRVFLPQDVWGAQVRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4A8</accession>
    <name>A0A2G4F4A8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56575">
        <property type="protein sequence ID" value="PHX56575"/>
        <property type="gene ID" value="CP500_004835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="6791" checksum="27AB4D5C7B6AA50C" modified="2018-01-31" version="1">MAIAFYLIYDIILISVIAHILHHISRTGKMPVPQRVNFIVDQAGKPVHKRLIENGTISQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4B5</accession>
    <name>A0A2G4F4B5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:48908"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:12252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:90840"/>
            <dbReference type="EC" id="2.4.1.255"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56327">
        <property type="protein sequence ID" value="PHX56327"/>
        <property type="gene ID" value="CP500_005955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037919">
        <property type="entry name" value="OGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366">
        <property type="entry name" value="PTHR44366"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="109"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="178"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="212"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="246"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="280"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="348"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="382"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="416"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="485"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="540" mass="61293" checksum="C6B7732174B3FE00" modified="2018-01-31" version="1">MNSEIVTLDFQQQAELYLAVGKLDEAIALCQQILASDPNSAETCKTLGKALQAQGKLEDARYWYKVAIALKPDFPEAFANLGTLCATLEQWHEAIACYQKAISLQPEFAGFYRNLSRVFTQIGKAEEATDCWYQALMVAPVEIPEEYLDLGNTLLAQNKLKLALICYHRTIYLNPSFCEAYDKLADAYSELQQWKEAITNYRKAIKIQPDISEFHYKLGNALQASGLLHEAVAAYRESIELNPNSFSSYYNLGSVMLKLENWQQAIIAYRTSVEINPDFSWSYYSIGEACDKLEKWSESATAYQRATELDPNSFAAFHKWGDALCKLEKWLEAGAAYEGAIALNSDSFWSHYNLALTLVKLQKFAPAIIAYQRAIALNPEFSWTYHNLGEVLLKSQQWKAAATAYQRAIELNPNISWSYYNLGDALTELHEWNDAVSAYLDALQLDHSLPNLYTKLGEVLTKRTPVSLDLATSYYHHEMQPLYSSEFYSQVAQKFADRDRLDAAAALYLMALEVRPKDPEISQKLEEILEKQRQTGEISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4D6</accession>
    <name>A0A2G4F4D6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56620">
        <property type="protein sequence ID" value="PHX56620"/>
        <property type="gene ID" value="CP500_004540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="8"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="19341" checksum="4EED1CD2B12980D0" modified="2018-01-31" version="1">MSDLYISWSDYHRKIEDLAVKIHQSQWKFDRIVCIARGGLRAGDILSRIFDKPLAILVASSYGGTEGKVRGSIKFARDLTMVGDDLGNRILLVDDLVDSGVSLEQSILWLKSRYTEDIQEIRTAVLWYKACSVAIPDYYVDYLADNPWIHQPFEIYEKMSAADFAAKVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4J9</accession>
    <name>A0A2G4F4J9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56704">
        <property type="protein sequence ID" value="PHX56704"/>
        <property type="gene ID" value="CP500_004135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="576" mass="64197" checksum="360C6AF36C7E9085" modified="2018-01-31" version="1">MKKIILLTLYLIPVVLLIGFVANFSVNVPIDDEWRLAGLFDKIATGNVSFNDFWALHSNHRIIFPKIIIAMLAFVSRWNINYPLCLSIALAVITFVATYKLSSMQVKNVGDDLWHLANILTCILLCSLVQHENWLWGFQLAWFLVNLCFVSAVYCLSLQKRLLPSIKILIATGFCFIASFSLAQGLLSWLAAIPAVVALEGNVAQKRKRLIVWMLLFVATCAIYSIDYHPSRKTSIILLLNKPLLVIDYFLSLLGSPIVRSPVISALVGLAIFATFLFLAFHFGRKMNEHHEAIPWLSIGLFAVLSALFITAGRAQFGAIQAIESSRYTTNSILLLIALVQLGQLFVRGNIATLNRNYKFVYRVLAGGLIGIIIVNSGQAIAQTASALPYKQGGKDCLELINYLEPSDFFNNSTESCLRVLSKKTWLVREGAQILDKIGWRKLAKNVEFIANPGKIYGYFDQPQIGDKSLTINKDNAIKATGWAVLPEKLQQPNIVLLSVGDKPSFFANAYVNLDSPDIAKTLKSQVYSNARWAIDLAVHDLPIAQTEIKAWVYNPVDNQFVKLRGGARVTVEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4P0</accession>
    <name>A0A2G4F4P0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Small-conductance mechanosensitive channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_003580</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56708">
        <property type="protein sequence ID" value="PHX56708"/>
        <property type="gene ID" value="CP500_003580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="8">
        <location>
            <begin position="352"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="490" mass="54455" checksum="5144AF48B5017CF0" modified="2018-01-31" version="1">MGNLNWQESGLIWVIVLGIGFPLLVILLGEVIQRLKRQGNPLASTLRTVKNLVLPSFALMIFVRDVFKLDPQATLVKVIQTLFWICVINAALSLINALLFEQAEADTWRGRMPKLLVDLCRVVSIFVGGAIVLSEVWGADLAGLATALGVTSIVLGLALQDPLGSILMGIMLLFERPFNIGDWLKVGDAEGQVIDMNWRAVRLLTEERQVFIIPHQILGKEVICNYTAPDRIYFGSIKVGFSYDNPPNVVRQVLFNTALSVPGILAEPEPDAQTISYDDFVITYKVEFFVKDFLQLESAQNEFMTRIWYAARRNNLTLYHYKYQCAVESNAGQTDSTASKLSQGFSAIPALIPVTREQSSLDQLTKGTILQHFGRGETAIRQGDRVFSMYIIISGEAVMTVLNDAGPELEVVKLSRGEFFGVMALFSREASPVSVTAVEDMEVMVINSDAVNAMIERQPSLSREIAQVIEMRRHAINIALRTSRNELVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4T4</accession>
    <name>A0A2G4F4T4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NAD(P)H-quinone oxidoreductase subunit I</fullName>
            <ecNumber evidence="11">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">NAD(P)H dehydrogenase I subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">NDH-1 subunit I</fullName>
            <shortName evidence="11">NDH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ndhI</name>
        <name evidence="14" type="ORF">CP500_003440</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 2 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">NDH-1 is composed of at least 11 different subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cellular thylakoid membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the complex I 23 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56794">
        <property type="protein sequence ID" value="PHX56794"/>
        <property type="gene ID" value="CP500_003440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01351">
        <property type="entry name" value="NDH1_NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004497">
        <property type="entry name" value="NADH_plast_OxRdtase_su_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47275">
        <property type="entry name" value="PTHR47275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00403">
        <property type="entry name" value="ndhI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01971">
        <property type="entry name" value="NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 11" id="KW-0408">Iron</keyword>
    <keyword evidence="8 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0520">NAD</keyword>
    <keyword evidence="4 11" id="KW-0521">NADP</keyword>
    <keyword evidence="5 11" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="2 11" id="KW-0874">Quinone</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="6 11" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="95"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX56794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="22172" checksum="6A07C497FB1235AF" modified="2018-01-31" version="1">MLKFLNQVGEYAKETVQAAKYIGQGLAVTFDHMRRRPVTVQYPYEKLIPSERFRGRIHFEFDKCISCEVCVRVCPINLPVVDWEFNKETKKKQLKHYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELAAYERHELNYDNVALGRLPYKVSDDPMVTPLREFAYLPKGAMDPHEVSSGDRRAGLRPEEIIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4X6</accession>
    <name>A0A2G4F4X6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56761">
        <property type="protein sequence ID" value="PHX56761"/>
        <property type="gene ID" value="CP500_003900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="302"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="405" mass="42835" checksum="DB1E8E53182BB4DB" modified="2018-01-31" version="1">MSLSFKQLTLYVTLLSIGGGIGWLGNRYLQSPNGLETGSVLPVVRQQIPPYASSQVPSNPPVDRTNSNFIAEAAQKVGPAVVRIDASSKVINQVPEAFKNPLFRKFFGNNLPVPEEKIKRGTGSGFILTTDGRIVTNAHVVSGTDTVKVTLKDGREFEGKVQGVDLLTDVAVVKINAKDLPLVALGRSDNIVPGQWAIAIGNPLGLDNTVTVGIISATGRSSSQVGIPDKRVRFIQTDAAINPGNSGGPLLNDSGEVIGINTAIRADAQGLGFAIPIETAKRVSDQLFAKGKAEHPYLGIQMVSLTPATKAEINKQLNAKIALNKGVAVIRIVENSPAQKSGLRPGDVIEKIDGITVDNPGDVQERVENTVVGKELEMQINRQGQIQKIKVRPGAFPISGNSAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Y0</accession>
    <name>A0A2G4F4Y0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56798">
        <property type="protein sequence ID" value="PHX56798"/>
        <property type="gene ID" value="CP500_003470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="6"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="150" mass="17246" checksum="2E81D0C5E8217908" modified="2018-01-31" version="1">MSISDLTRQAVRERAKYLCEYCHSPERLSANRFTIDHIIPRSLEGSDEISNLALACRRCNERRYNFVAGIDSETQEIVPLFNPRSQKWAEHFVWVDGGVVIDGVTPTGRATCTRLDMNDMRYPEEDSIRATRRFWIQTGLHPSPSDPCQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Y5</accession>
    <name>A0A2G4F4Y5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phycobilisome protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56771">
        <property type="protein sequence ID" value="PHX56771"/>
        <property type="gene ID" value="CP500_003955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="2" id="KW-0157">Chromophore</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="18242" checksum="8B717270D98CAEA6" modified="2018-01-31" version="1">MHPEIEALLDQAENRFLKPEEITAFKRQAATLSQRLKIYEFLRDKEESIFQPVANKLQETFPDEKQEILERSLKHWLLVLRYCAMAMLLNDQIFLEQRLLDWLSGLVEAHQTHKIEATVCNLLQTRIKELLSEQARAILQPFLDQAQSIIIGASQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F507</accession>
    <name>A0A2G4F507_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc metalloprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_003195</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56819">
        <property type="protein sequence ID" value="PHX56819"/>
        <property type="gene ID" value="CP500_003195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016483">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006404">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="308"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX56819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="367" mass="38980" checksum="F2BA01F4BD570A4F" modified="2018-01-31" version="1">MNGTFRVGNLFGIPFYINASWFLVLGLVTWQYGGALAAIFPTLGPVAPWMLGLFAALLLFASVIAHELGHSWVAIKQGIGVKSISLFLFGGLANLERESKTPAEAFWVAIAGPLVSLLLSGLLTAIGIAAGLTGPAAAIVQLLAQINLALALFNLIPGLPLDGGNILKAIVWKITGNPYKGVIFASRVGQIIGWIAIATGIFGNIWNLVIGWFLLQNAGQSAQYATVQNQLAGLTAADAVTPGSPIVSQDLSLREFANNYVIGNAQNWRRYLVTDDAGQLVGAIETDDLKAIPTGNWPSVQVKELLKAIEFSATVEPELSLLEVVTLFEQLKVQELPVIRGNGVLVGLVEKAEIARLLEKRALGNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F584</accession>
    <name>A0A2G4F584_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56944">
        <property type="protein sequence ID" value="PHX56944"/>
        <property type="gene ID" value="CP500_002905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="9545" checksum="2EF04F1A2E1EAB03" modified="2018-01-31" version="1">MSKVGCGPPNFFEGDGSFFNRRCCTILNQLFMGGLEAHPTRIIFIVEQASCLLLTLVQDVSLTADESRARRRRHNGRGCGLRAIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5D8</accession>
    <name>A0A2G4F5D8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56921">
        <property type="protein sequence ID" value="PHX56921"/>
        <property type="gene ID" value="CP500_002785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="24"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="334" mass="37044" checksum="5294996D69CC170A" modified="2018-01-31" version="1">MDAALFLEKLAEQQAEAEVVLDVSAVVPVYNEVESLPHLIEAIATSIKASGLSYQIICVDDGSKDGSAELLQQLASSRDDLCAVILRRNYGQTAAMSAGFDRARGRAIVTLDGDLQNDPADIPLLLAKLDEGYDLVSGWRKNRQDNTVSRLIPSKIANWLIGRVTGVVLHDYGCSLKAYRSELVADLNLYGELHRFLPALAFIEGARIAELPVRHHARRFGQSKYGIWRTFRVLMDLLTISFMKKFLTRPMHVFGLLGMSSMALGTVLGIYLTILKLGFGQIIGNRPLLILAVVLVLTGVQLFCFGLLAEVMMRTYHESQGKPIYRVREVFGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Q2</accession>
    <name>A0A2G4F5Q2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CP500_001555</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57114">
        <property type="protein sequence ID" value="PHX57114"/>
        <property type="gene ID" value="CP500_001555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="19">
        <location>
            <begin position="373"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="17">
        <location>
            <begin position="430"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="17">
        <location>
            <begin position="579"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="18">
        <location>
            <begin position="653"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="17">
        <location>
            <begin position="704"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="18">
        <location>
            <begin position="779"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="15">
        <location>
            <begin position="849"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="16">
        <location>
            <begin position="1105"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="687"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="12">
        <location>
            <position position="1154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="PHX57114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1314" mass="147733" checksum="4E1B1A59B42C8926" modified="2018-01-31" version="1">MFPKQLNRLATKIIGKAPLQTVLVVPFLVQIVGTVGVVGWLSFQNGQLAVNDVAAQLRREITDRIKDRIGNYMSIPHIVNHLNVKGIKLGELNLEDKQKLEHHFLEQIQYFDSISIIYVGKENGEHSGAIQTKDRTLISAADSSTGNKLSRYTSDAQGNRVKLVQISSTIYDPRMRLWYMTAATAKKPIWTQIYTDFLTRDLAITAAMPIYDDSGKLLGVAGSDLLFSRIKEFLTSLKVGKTGQTFVMERSGMLIATSTKTPDFTVERQQVKRIKASESNNAVIRQTGQYLETIYGKVGKINDSQQLTLEIEGKRQFLQITPFKDDRGLDWLIAVVVPESDFMEQIHTNSHTTIFLSVTALITATILGIITAKWVVKPILRLNAAAKALANNEFDTKVRSDREDELGELAHSFNSMAEQLQHSFTSLRESESRLKQFLNAIPIGIFIVDSQGKPYYINPTGEKILGQDILESNPENIRKYYRAYLAGTKEVYPAERDPILNALQGKSVTIDDIEVVRINKTIPLEVSGTPIYGEQGNIIYGMCAFQNITERKLSEKLSREYNQNLEAQVVQRTAELAKAEEKFSKAFHLSPNAITLTRMSDGRHIEVNESFCRMMGYSHEEIIGKTAVELNFWATLAERDRMIQVLKNKTAIQNYELQFRNRSGKERTALLSIETIDIDGESCFLSISSDISDRQKAETALREAEEKYRNIYENALSGIFQITPDGQYLSANPALAKLYGYESTEELVAAQPNLKNQLYVNPQRRQEFMSLMNLYGILSNFESQIYRKDGSIIWVSENSRVVCDEEGNLLYYEGFIKDITANKEAEIQMQQAKEAAEAANKAKSTFLANMSHELRSPLNAVLGFAQVMIRSKSLSKDNQENVGIILRSGEHLLSLINQILDLSKIEAGRTTINERSFDLYRLLDDLEDMFALKAEEKSLQLLFDRDAEVPHYIYTDEVKLRQVLINLLNNAIKFTSSGGVSVQVRGGLQNKQNNSNAKIPGCYSLHFQVQDTGEGIAPDEINQLFEAFVQTKTGKDSQEGTGLGLAISRQFVKLMGGDITVTSEVEKGTIFQFDIQVHLVEDADIESKKTKLRVVALEPNQPRYRLLIVDDKPLNRQLLVKLLSPLGFELREANNGQEAVDISLEWEPQLIWMDMRMPVMDGYEATKQIKTTTCGQATAIIALTASVLEEERAVILSAGCDDFMRKPFREEDIFTAISKHLGVRYIYEYPTEASVAGSGDDRQEVLTPLAIGSLPSEWVATFNQNILSVDMEAIASSIEQIRTVNSSLADRLQDCINNFEYDRILSVIAKIEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Q4</accession>
    <name>A0A2G4F5Q4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57055">
        <property type="protein sequence ID" value="PHX57055"/>
        <property type="gene ID" value="CP500_001870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045511">
        <property type="entry name" value="DUF6439"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20035">
        <property type="entry name" value="DUF6439"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="93" mass="10124" checksum="3DA8C42DC8A8E4BF" modified="2018-01-31" version="1">MLETTQTPKTVNLNELSTVELAQALAARLAISEKDWHRLKANRSARACEQAGAALVFLLKNQPEEALPRLNQAAGWLDRSISAPPCPTHGHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5W1</accession>
    <name>A0A2G4F5W1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_002035</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57081">
        <property type="protein sequence ID" value="PHX57081"/>
        <property type="gene ID" value="CP500_002035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015099">
        <property type="term" value="F:nickel cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0533">Nickel</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="492" mass="53688" checksum="CE5A200687B3DCDF" modified="2018-01-31" version="1">MQNKSKRFPKHFILFFLTLSLLLTTSINPVYSHWADLSVAEIVVNDSQTEITLTFPTGLTKFADDNQDSQLQPAEVRNHQTQLEKFFSENITIKNINKIPGNISIISLEIAAKTANLIQQPNTHSTLILDYTWPAVAQIPTPNLPTSNLTSKSKFWINYHLFLPGITTASCQATIVQAGAIKSFVFTPQNREFLVAQNESIWEASWSLLLALAGAFAWGAIHAMSPGHGKTIVGAYLVGARATPLHAIFLAATTTITHTAGVFAVGGITLFASHLIDPEKLNPWLNLISGFLVALIGFKLLIERTKNRFGLKNSVFKYFKTKIVNQNWDLRTKVLTMNYDEPVNLLNRGSWEREFKPVKPKISEHYHHHGDGRVHSHLPPGADGSPVTWKSLLALGISGGLLPCPSALVMLLSASALGSVGLGMTLVVAFSLGLALVLTAIGLILVYAKGKFDKLPKQMAVVQFLPGISAMLVMLLGLGITGQAMLQILATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F608</accession>
    <name>A0A2G4F608_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 1</fullName>
            <shortName evidence="5">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">prfA</name>
        <name evidence="8" type="ORF">CP500_001665</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57131">
        <property type="protein sequence ID" value="PHX57131"/>
        <property type="gene ID" value="CP500_001665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCRF" evidence="7">
        <location>
            <begin position="68"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="261"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="5">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="365" mass="41293" checksum="10240CEFF124B191" modified="2018-01-31" version="1">MAESYLLDKLKSVEQTFHELTRRMADPDVARDNYEFQRVAKARSSLEEVVDTFELWKITQDDLVGARQVLKEAASDREMQQMAALEVEELESKSEHFESRLKVLLLPRDPNDDKNIMLEIRAGTGGDEASIWAGDLLRLYSRYAQTQGWMVKLVSESLADMGGFKEVILEVTGDSVYSKLKFEAGVHRVQRVPLTEASGRIHTSTATVAVMPEVDDVEIHIDPKDIQMSTARSGGAGGQNVNKVETAADLFHKPTGIRIFCTEERSQLQNKERAMQILRAKLYEIKLRQQQDEVKELRLGQVGTGSRSEKIRTYNYKDNRATDHRLNENFSLNSVLEGDIEEIIQTCISQDQQDRLAQLAASTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6A8</accession>
    <name>A0A2G4F6A8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_000655</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57324">
        <property type="protein sequence ID" value="PHX57324"/>
        <property type="gene ID" value="CP500_000655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="251" mass="28143" checksum="41783EE4D1D1CD51" modified="2018-01-31" version="1">MPSNNETAVQCFDVTYRLNRRNLVENLNFKVLQGEVLVLLGRSGSGKTTTMKLINNLLTPTSGEITVMGKPTTQWNSIQLRRKIGYVIQEIGLFPHFTVEQNIGLVPKLEGWEGDRIQSRVHQLLKLVNLDPQHFAKRYPSQLSGGQRQRVGVARALAADPPLLLMDEPFGALDPITRLELQREFYQLQQQLGKTVILVTHSIQEAFLLASRIGLMQDGRLVELASPDDFMKSQQPEAIAFLECLQLPGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6B3</accession>
    <name>A0A2G4F6B3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57296">
        <property type="protein sequence ID" value="PHX57296"/>
        <property type="gene ID" value="CP500_001160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="8254" checksum="2D9DD284C32582AD" modified="2018-01-31" version="1">MSTYSTVLTQVLKLAPDEQMRLISELFAHIRQRMIPKPKRSILELSGLGKEIWHGIDAQEYVNQERNSWNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6E3</accession>
    <name>A0A2G4F6E3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_000665</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the integrin beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57326">
        <property type="protein sequence ID" value="PHX57326"/>
        <property type="gene ID" value="CP500_000665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015812">
        <property type="entry name" value="Integrin_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002369">
        <property type="entry name" value="Integrin_bsu_VWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10082">
        <property type="entry name" value="PTHR10082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00362">
        <property type="entry name" value="Integrin_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01186">
        <property type="entry name" value="INTEGRINB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00187">
        <property type="entry name" value="INB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0401">Integrin</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="VWFA" evidence="9">
        <location>
            <begin position="335"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1085"/>
            <end position="1116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1253" mass="132845" checksum="196411C9D55C37EF" modified="2018-01-31" version="1">MQLLKDDVLLGSSVDVSAIAPLEEEIKGDRILSYGLDTRSASQLGASSSFISTFDGLSGQVGTIDPSAKFTQIASTFSFSDIAVAKDGTIFGITPTQLFKIDPVSGLTSFVGGLPAGVNMNALEFANDILYAAGDSNLYAINTTNAGAYLIANLESAGFNSSGDLAFDAPNNRFLATSKGATSDSLYAVSLTGEAAKIGDIGFSNILALMFEGEKLFGFTADGSRIAINPGTGAGVFDTLVKGISDRIGGASGIQIKKGEVLSSTPGTILSADTIDVFLPPGGEITLDITVTVPGDASSSTTRSGLSVGTDTVVAQMLSSSAVSASATSGQLPLDVFLLQDASNSFSDDVSIFRRLVPNLVDTLSNQQPNTQFGLGSFVDKPIEGIGNIEDGHYVYRTNLPLTKNENELQSAVNNLTILPSNSTDPEASLEALLQTARRADTAEIGFRDSARRVVVLATDNEFHQAGDGAILAGITRPNNGDAVLDGNPPGTGEDYPSIQQVREALIDTGIVPIFAVTSKSNNNVNNISVYNDLVNKLGFGKVVRLDSDSANLVNAITEGLDKVSQEITLVPADDDFSYVKDISPKKFENVKPGDKLTFKVTLKSDSTGRDDNLKLQIPGFGNLGDTKVNVRTERVPTLVNNDTGGTSQEIGFIKNRISLDPTFRPTVIMRSFQDKNNDVNPDFDPTMPVKNIETYVVIHGNLDTVNSGKMAALAKTISDQNKQVIVLDWSVSADNQLPNISAGSIHDVAKFAVDTLKNKWKIDSKNLNLIGHSLGSYVASEIGFILSNKEPDKELNPQYRQNPNIDQENRVNSLTALDPAGLFGGNLPSSGLYDLDASLNFTDVAGAQNPIKFSSVSKFSRAFWGDFASGDGLGSSDYATSANESIYIDVKKPDTAFKDLTSPDASHGDIVYLFRNLLKEPGEIANLFKLGQGKHSEWRENTFGGNEGILVANRSNNEGNDPNISPSLLFLKDKNTQNDDIAYGSIGDDNLDGGLFERNSIIVVPTPQGVFVTQTDDATFNGLGNDKLYGDLGNDKIFSGSGNDTLYGASGNDFINAEEDNDLIEGGDNNDTIFGAKGDDTVIGGKGNDSLEGNDGKDTLSGGDNDDTLWGGGGDWADSLEGGDGNDYLFGEGGDDILIGGKGKDIIDCGGGNDTLVFGLDDGSTSLDGADIITNFRTGKLLGFISTGDARGVTKIKLNGLIPGNLEVMKIDNNKTLLWSQKNDLDLYTVFKQDTYFAILDGSFNKDQLTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6J0</accession>
    <name>A0A2G4F6J0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57311">
        <property type="protein sequence ID" value="PHX57311"/>
        <property type="gene ID" value="CP500_000575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045397">
        <property type="entry name" value="DUF6516"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20126">
        <property type="entry name" value="DUF6516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="16167" checksum="1C9FD9F25F2063D7" modified="2018-01-31" version="1">MSEAPLNSLSEYNRFVSQILTRPDIERSTVVVWSNSPYTGTAEGEVWFTRNVRLRMREELDFDAGLITAYGYEVYQGSEKLYWYDDFPHPQDPSLASTFPHHKHIPPEIKRNRVPAPDISFTRPNLPTLIQEIEALIAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6T6</accession>
    <name>A0A2G4F6T6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57441">
        <property type="protein sequence ID" value="PHX57441"/>
        <property type="gene ID" value="CP500_000455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="133" mass="13896" checksum="CF4458C527B6EEE8" modified="2018-01-31" version="1">MPDIVDIAVGAGCFQTLVTAVQVANLVDALKSPGPFTVFAPNDDAFAKLPPGTITTLVQNVPQLSRILTFHVVSGKFMKADLAKLGFVTSLEGSPIKIDCSDGFEVKNATVVAADIEADNGVIHVIDTVILMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6U3</accession>
    <name>A0A2G4F6U3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57277">
        <property type="protein sequence ID" value="PHX57277"/>
        <property type="gene ID" value="CP500_001155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="14"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="16618" checksum="B9D220062945B721" modified="2018-01-31" version="1">MEWIAQLQGKVVGLDTAPLIYFMEQNPKYLEMMLLFFRSFNRGDFRIVTSTVTLVEVLVHPLRQGNTILAQEYREILMNQESLTVVELTPDIAETAAQLRATYNLRSPDSIQMATAICEGASFFLTNDARLPSLPGLTVLVLEHLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F730</accession>
    <name>A0A2G4F730_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4325 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57417">
        <property type="protein sequence ID" value="PHX57417"/>
        <property type="gene ID" value="CP500_000320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025474">
        <property type="entry name" value="DUF4325"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14213">
        <property type="entry name" value="DUF4325"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4325" evidence="2">
        <location>
            <begin position="73"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="234" mass="27623" checksum="C69D9F3A33F1A6C9" modified="2018-01-31" version="1">MTQVSDREQEIILQLRTLSPEHQRAVIDLIGALQVPATKSQEYQPESQGHDSDIKINLYQVLGKFELTFEHEGQVIYPLIAEAFKQGKKVVVSFEKVQLITWSFVTKAIGQLYEHFSESQIQSCLQLVDLSEEDLEFVHHVIETKKEFLVNPEKFRQPMSDEQLEELRRKNPDNPILQVVGMFKDDPTKEYWLILGYFLRFVFWRIFRLLILMQWPIAIICNYRRKKLELGLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUD0</accession>
    <name>A0A2G4EUD0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromophore lyase CpcS/CpeS</fullName>
            <ecNumber evidence="3">4.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cpcS</name>
        <name evidence="4" type="ORF">CP500_023040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CpcS/CpeS biliprotein lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.-.-.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000261">
        <property type="protein sequence ID" value="PHX53152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53152">
        <property type="protein sequence ID" value="PHX53152"/>
        <property type="gene ID" value="CP500_023040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017009">
        <property type="term" value="P:protein-phycocyanobilin linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01459">
        <property type="entry name" value="Chrphore_lyase_CpxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018536">
        <property type="entry name" value="CpcS/CpeS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09367">
        <property type="entry name" value="CpeS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="18887" checksum="8CE38C141F586653" modified="2018-01-31" version="1">MDVIEFFELSAGKWFSQRTVHNLNSGELQAGKSDLRIEMLTPTEPEVVKLCQQHSIDPTSTGLTSIRVSWDGTPDRTEQKQIGSTILAVLPNPDNPSEGKVLQDKGNTRYVMGSDDVLTLITESETIHAEERLWYLIPNLRLRTSVVKQANGTEQASFCSEIRMGVGPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUP1</accession>
    <name>A0A2G4EUP1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_023070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000262">
        <property type="protein sequence ID" value="PHX53150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53150">
        <property type="protein sequence ID" value="PHX53150"/>
        <property type="gene ID" value="CP500_023070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7216" checksum="AA07D565C21A79DA" modified="2018-01-31" version="1" fragment="single">EKTCTELRSELSDLKQKSATAGKDLPDAADLLNQLKAKRKKSTASFTDIEAVLKIIEDSQNHSTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUV3</accession>
    <name>A0A2G4EUV3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000217">
        <property type="protein sequence ID" value="PHX53319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53319">
        <property type="protein sequence ID" value="PHX53319"/>
        <property type="gene ID" value="CP500_022170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="178" mass="19744" checksum="E42DE30AE5C66043" modified="2018-01-31" version="1">MTSEKLEIVQTEYQTGKIAFESGRYAQAVKSLETARGLVDRNSRLGGEVQMWLVTAYEASGDTESAIALCGKLTRHPRLETRQQAKRLLFILEAPKLSIPPEWMVKIPDLTALEENESSSFQVGPNVSFAKPVTPKRSVVPEPVDLSQVNTQDNRFIWVALIAIFLILGGLFITNGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUY1</accession>
    <name>A0A2G4EUY1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Nucleoside diphosphate kinase</fullName>
            <shortName evidence="3">NDK</shortName>
            <shortName evidence="3">NDP kinase</shortName>
            <ecNumber evidence="3 5">2.7.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Nucleoside-2-P kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ndk</name>
        <name evidence="7" type="ORF">CP500_022540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">(Microbial infection) Catalyzes the phosphorylation of dZDP to dZTP, when the bacterium is infected by a phage that produces the substrate for the synthesis of dZTP (2- amino-2'-deoxyadenosine 5'-triphosphate), which is then used by the phage as a DNA polymerase substrate.</text>
    </comment>
    <comment type="function">
        <text evidence="3">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + dZDP = ADP + dZTP</text>
            <dbReference type="Rhea" id="RHEA:67644"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:172929"/>
            <dbReference type="ChEBI" id="CHEBI:172931"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="3 5"/>
    <dbReference type="EMBL" id="NXIB02000232">
        <property type="protein sequence ID" value="PHX53240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53240">
        <property type="protein sequence ID" value="PHX53240"/>
        <property type="gene ID" value="CP500_022540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDP_KINASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="6">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="3">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="149" mass="16280" checksum="EA89F5943B3CE2F9" modified="2018-01-31" version="1">MERTFLAIKPDGVQRGLVGEIIGRFEAKGFTLVGMKLITATRELAEQHYGVHKERPFFAGLVNFITSGPMVAMVWEGDGVVASARKIIGATNPLNSEPGTIRGDLAVNVGRNIIHGSDAVETANEEISLWFKDEELSAWTPCLTPWIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV00</accession>
    <name>A0A2G4EV00_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000207">
        <property type="protein sequence ID" value="PHX53372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53372">
        <property type="protein sequence ID" value="PHX53372"/>
        <property type="gene ID" value="CP500_021845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="18416" checksum="F03900C64A02072D" modified="2018-01-31" version="1">MTTSAQKNQTEISNTVSSNPQMLSFLKIIEYLSLAAFAGVCILTRVFPDNQLVVIWGAVFLSSFIFIFLTNRQLGQNSRNRTNQLELARKAELYSYLLNPNNSSDHNLITPVRVKALRYCQELIDDYKKTRETSRNIYYTFQLATVILSGVTPILVLVDKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV88</accession>
    <name>A0A2G4EV88_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000194">
        <property type="protein sequence ID" value="PHX53462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53462">
        <property type="protein sequence ID" value="PHX53462"/>
        <property type="gene ID" value="CP500_021395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="259"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="502" mass="56450" checksum="6F3F726DFBFC599A" modified="2018-01-31" version="1">MTNFSDEFELLLRSRYPLIYIPTREEERVEVAIAQSAKKQGARAVYTWDFVDGYQGNPNDAGFGKRNPLQALEFLEKLPTSAPAIFILRDFQRFLEDVAISRKLRNLARLLKSQPKNIVIVSPIISIPEDLSEVMTVLEFPLPAAGEIKIEVEKLLGAIGQAIEGRLLDEMVRSCQGLSIERIRRVLAKAIATRGELHSDDAELILEEKRQTIRQTQILDFYPARENISDIGGLDNLKEWLLRRGGAFSDRARQYGLPHPRGLLLVGIQGTGKSLTAKAIAHHWHLPLLRLDVGRLFAGLVGESESRTRQMIQLAEALAPCVLWIDEIDKGFGGLEGKGDSGTTSRVFGTFITWLAEKTSPVFVVATANNIQSLPPEMLRKGRFDEIFFVGLPSQEERRAIFEVHLLRLRSHNIKNYDMERLAYETPDFSGAEIEQTLIEAMHIGFSQNRDFTTDDILESASQMVPLARTAQEQIQFLQDWAAAGKARLASRYGSLSRRIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVG4</accession>
    <name>A0A2G4EVG4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_022950</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000254">
        <property type="protein sequence ID" value="PHX53167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53167">
        <property type="protein sequence ID" value="PHX53167"/>
        <property type="gene ID" value="CP500_022950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="96"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="164" mass="18811" checksum="9D279861267033D9" modified="2018-01-31" version="1" fragment="single">MKIFQRLLSLIVRFAIKLFQMLLSLIKPKVKSRSTKYLQQFAEARTTTEAEKLSRELNQQVVQLYNEGKFNEAILVAEQALILAKSLYPGDHDNVASSLNNLGFLYQSQGRYGEAEPLYRQALKMRQRLFTGDHDNVASSLNNLGFIYQSQGRYGEAEPLYRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVH8</accession>
    <name>A0A2G4EVH8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PEP-CTERM sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000251">
        <property type="protein sequence ID" value="PHX53177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53177">
        <property type="protein sequence ID" value="PHX53177"/>
        <property type="gene ID" value="CP500_022880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013787594" evidence="1">
        <location>
            <begin position="32"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="265" mass="28176" checksum="62E48E073D7ED69C" modified="2018-01-31" version="1">MTTLTLVKKTSFAVSSLVATLILSICTPASAFMFGTSGIQFDEDTTIGFTFDGSHGAYQSSLRVAQAESGNGYSNKSILFNETKASDNGSTNNWEGTFGNSVTSPNGSLNQTFTFLKDQIYALLLWNDLGSGNPLEQYVSSSTFMNSSEWFAAGTQFRRTDCLAIGCQQAVFGDFSLNNDSTAPFSTVNGGKGPEQFQSVTLAQLAKGTKISFDDGGKGSDVDFQNFSLTAQVVPEPISVLGTILGIGALGVARSKKKQCQQTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVQ9</accession>
    <name>A0A2G4EVQ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000180">
        <property type="protein sequence ID" value="PHX53546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53546">
        <property type="protein sequence ID" value="PHX53546"/>
        <property type="gene ID" value="CP500_020935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013942023" evidence="2">
        <location>
            <begin position="23"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="87" mass="8583" checksum="63690E77613C3FBB" modified="2018-01-31" version="1">MNKELIRLTLVLGLVATLGACAGETAPTATPSTGSETSSPATTSTPEPKESVKSTPGSDKTPGAEKSSTPKESASPSASPSASPKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVR2</accession>
    <name>A0A2G4EVR2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Prim-Pol domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000228">
        <property type="protein sequence ID" value="PHX53257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53257">
        <property type="protein sequence ID" value="PHX53257"/>
        <property type="gene ID" value="CP500_022450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015330">
        <property type="entry name" value="DNA_primase/pol_bifunc_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09250">
        <property type="entry name" value="Prim-Pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prim-Pol" evidence="1">
        <location>
            <begin position="50"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="229" mass="25745" checksum="6C675B8BE823081D" modified="2018-01-31" version="1">MSDINQAPQTIDWLHNCLGRPALPESQGMRGGLRRSRRQSACLDKPEGKAVKVSWKPYQKQLPTQANLGKWFARTTGIGTLGGGPNIQGHYIAFVDLDRKEKVFSSPQAFEARLEQWFNDYPLLNVAPRFRTPSSGYRVILAFTEEPDWTAFSLDRDRSRMGELLARNGGHTLLPPTVGTNGIPYRWEYFVAYPPTVAKPEDVGIAQAKNRLHWTVPALSTPALRRSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVS4</accession>
    <name>A0A2G4EVS4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Insulinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_020960</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000181">
        <property type="protein sequence ID" value="PHX53540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53540">
        <property type="protein sequence ID" value="PHX53540"/>
        <property type="gene ID" value="CP500_020960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="3">
        <location>
            <begin position="86"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="3">
        <location>
            <begin position="181"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="4">
        <location>
            <begin position="285"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="531" mass="59560" checksum="19F3D53823FEA7B0" modified="2018-01-31" version="1">MISQSQKAREAKLSPRESLKRQTRFLASLVAAVLLWWGISPQIALARENPANGSKMASAVPSLDRVINQVSEFKLNNGMTFIVLERPRAPVTSFLIHADVGGADEPDGQTGVAHYLEHLAFKGTPKIGTTDYKAEKPLLEKQDQLFDQIQAAKASGKTEEVAKLRAEFDKTELESLKFVNRNEFGKIVEQAGGVGLNAATSIDATMYFYSLPANKLELWMSLESERFLEPVFREFYKEKQVILEERRMRTENSPIGQMVEVFADKAFSVHPYRRPVIGYSKDIENLTRSQVQKFFDTYYVPSNLTVAVVGDVKASEVKRLAQLYFGRYKAKPAAPKLQIVEPPQTQTREITLKLATQPWYLEGYHRPAMNHPDNAIYEIIGSLLSSGRTSRLYKSLVVEKQLALAAQGFSGYPGEKYPNLMLFYAQTAPGRTVDEVALALSQEIERLKTEPVSAQELEQVKTQARAGLLRSLDSNMGMAFSLLDYQVKTGSWRNLFKQLDAIAKVAPTDIQRVSKATFRPENKTIGKLLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVS7</accession>
    <name>A0A2G4EVS7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53578">
        <property type="protein sequence ID" value="PHX53578"/>
        <property type="gene ID" value="CP500_020770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="98" mass="11496" checksum="30BE7BF6769D5517" modified="2018-01-31" version="1">MKNVIFHPLAEQELIDATAYYEEQKPGLGLEFLGEVEEVVNFLMLYPEAGSNVGVSVRRVILPKFSYSLFYRILEEEQIRILAVAHHKRKPQYWVDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVT9</accession>
    <name>A0A2G4EVT9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-amino-4-deoxy-L-arabinose transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53570">
        <property type="protein sequence ID" value="PHX53570"/>
        <property type="gene ID" value="CP500_020730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="488"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="645" mass="73088" checksum="9A0F10E438D5C694" modified="2018-01-31" version="1">MTTYIFGFLPLVYLLILFLIFQKIDDCWRSAILSATIVWGVTIALSTEFFSLFKLVAFNWVFVLWLSADVLMLIIYLKAHNFKPNYSRNERNKFPGFLVVLLAGISLIFAAIGLIAIVSPPNNWDSMTYHMSRVVHWMQNHSVEHYPTSYVPQLYHPTWAEFAIMHFQIISGGDRFANLIQWLSMVGSAIAVSLIAQQLGANQRGQVFAAVFAATLPMGILQSSSTQNDYAVCFWVVCFVSCGLAGMSAGITGINTLKIGASLGLALLTKTTAYIFCLPFIVWFIVVGIKRYHEKMLPPILIIASVTMILNIGHFGRNYDLFGYAIGAPQDFTKEYKIEIFTIPTFLSNIIRNLAMHTGTSISQINGLIVAVVKLLHKILGVLPNDPRITWPPGQVYALTTPSFNENNATNPIHFGLIFATIILILNQPKLRKIKIVIVYLTATISTFLLLCLLIKIQPWHSRHHLTIFVLFAPIFGLTFSQLFNYKIANYIVSILIFMSLPWIAHNKFRPILAESNIFNTSRNELYFISRPNIEFAYNQAVDFVKSQNCTNIGLSFWTKNAWEYPLWVLFQEPGKPAPRIEHISTIDPVVGQKLNSEPYNSFVPCAIIYQSTKNDDKQGKEMVVKNETYVQKFSLEPLRVFMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVU3</accession>
    <name>A0A2G4EVU3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C-3',4' desaturase CrtD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">crtD</name>
        <name evidence="4" type="ORF">CP500_020340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000167">
        <property type="protein sequence ID" value="PHX53651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53651">
        <property type="protein sequence ID" value="PHX53651"/>
        <property type="gene ID" value="CP500_020340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016116">
        <property type="term" value="P:carotenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045892">
        <property type="entry name" value="CrtISO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014104">
        <property type="entry name" value="Myxoxanthophyll_desat_CrtD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313">
        <property type="entry name" value="PTHR46313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02733">
        <property type="entry name" value="desat_CrtD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="530" mass="57838" checksum="F13787E1C5B33836" modified="2018-01-31" version="1">MVSDRTPQRKSSVTVIGAGIGGLTAAALLARKGYKVLVLDQAIVPGGCASTFKRKGFTFDVGATQVAGLEPGGIHHRIFSELDIELPAATPCDPACAVFLPGETAPISVWRDPQKWQQERQKQFPGSEHFWQLLSTLFQASWKFQGRDPVLPPRNLWDFWQLTKAVRPDTLITLPFTFMTVGDALRLCGLGDNLRLRTFLDLQLKLYSQVDSEETALLYAATALGVSQAPQGLYHLQGSMQVLSDRLVSAIERDGGKVLLRHTVESIITTNGKATGTTIRNQKTGEVWTENADNIVANVTAQNLVKLLETDSIKSQNSAKISDKSVIKSAVSKLPNQMSGYKYRVDKLPPASGAFVIYLGVKEGAIPANCPPHLQFLYDYDGEIGENNSLFVSVSHSGDGRAPKGMATVIASSFTETRMWWNSVDYEGLKQKYMEGAIARLSEYFDLSSGAIVHQECATPRTFARYTARDRGVVGGIGQRVPTFGPFGFANRTPIQNLWLVGDSTHPGEGTAGVSYSALTVVRQMEAQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW38</accession>
    <name>A0A2G4EW38_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_019725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53745">
        <property type="protein sequence ID" value="PHX53745"/>
        <property type="gene ID" value="CP500_019725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022138">
        <property type="entry name" value="Helicase_SWF/SNF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12419">
        <property type="entry name" value="DUF3670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="651"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="942"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1123" mass="125436" checksum="2839CE7B4F782299" modified="2018-01-31" version="1">MAILHGSWIIDSQESCLFIWGEVWRKTEAIDTIESGMNLHHPLAMTESELKTFLTSLQQSGKLNWQLPETAEPTQEKGKKTRRSSSRALLTAKTETAQVIPQKSSVKKEIRAIALPTQISASNPNLVMPQHSAAALAEPPQTEEIYLFPWQVEGFCLNPQTAFIFLQALPLNSTATDSFVGSDLRFWSHIARWNLDLLARCKFLPGLEKQSDGSAIAKWQPLLDSSIDQLRLATFVKQMPTACRTYQSKEEGSSAADFVTDLTDARASNSTTASKVRDIAVDLPMGAQELVLGFLSSVVDSQVRSSSRAALTAISSNIGSTLEIKAVSPTREWLQSLQQESGIVQAESSALENMITKLSAWTAPLQNALSQQHQFRTCFQLMPPSFGTAEWSLNYCLQAADENELLVDARTIWNNSVESLNYAGRTIQLPQETLLSGLGLASKLYPLIEPTLQAQRPQSCPLKPLDAYNFIKSVAWRFTDSGLGVVLPPSLTHTDGWASRLGLSIKAETPKLNPAKGGMGLQSLLSFKWELTIGGQRISKAEFDRLVELNSPLVEINGEWVELRAPDVRAAKTFFASRKEQMTLSLEDALRLANGDSQTIEKLPVVNFEATGQLQELLNTLNNNEAVSAIAPASFRGELRPYQALGVGWLAFLERWGLGACLADDMGCGKTPQLIAFLLHLQENKTLENPTLVVCPTSVLGNWEREVKKFGPTLKVLLHHGDQRAKGKAFATAIKGKDLIITSYALVFRDAKEIQSIKWQGLVLDEAQNIKNSESKQSKIVREIEASFKIALTGTPVENRLQELWSILEFLNPGYLGPRNFFQRRFAIPIEKYGDRESLHTLRSLVRPFILRRLKTDKSIIQDLPEKQEMTVFCGLATEQATLYQQIVEMSIAELESAEGIQRRGMILALLVKLKQLCNHPALLTAKQNPKALEIKSQESGKLQRLLEMLEEVVAQGDRALIFTQFAEWGKLLKPHLEQHLGREILFLYGGIKQQQREEMLDRFQHDPQGPPIMILSLKAGGTGLNLTRATHVFHYDRWWNPAVENQATDRVFRIGQTRNVQVHKFVCTGTLEEKIHDMIESKKALAEQVVSAGENWITELDTDQLRNLLILDRNAIIETEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW45</accession>
    <name>A0A2G4EW45_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobalt-precorrin-6A reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_020200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000163">
        <property type="protein sequence ID" value="PHX53680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53680">
        <property type="protein sequence ID" value="PHX53680"/>
        <property type="gene ID" value="CP500_020200"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016994">
        <property type="term" value="F:precorrin-6A reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003723">
        <property type="entry name" value="Precorrin-6x_reduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36925">
        <property type="entry name" value="PTHR36925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02571">
        <property type="entry name" value="CbiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00715">
        <property type="entry name" value="precor6x_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51014">
        <property type="entry name" value="COBK_CBIJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="249" mass="26728" checksum="8A4FE4E453FDF7E3" modified="2018-01-31" version="1">MKKRLLILGGTGDATQLAARASQIANLDVVSSLAGRTKQPSTPKTGTVRIGGFGGASGLAEYLLDRAIDLLIDATHPFAAQISANAAVAAAECQLPHLMLVRPAWEAVEGDRWIEVESHSEAAMALSEKSQRVFLTIGRQELAAFASLDAIWFLMRAIDPPALDILYPNGKLLLAKGPFLLENERELLTEYRIDTIVSKNSGGDGTYAKIVAARELGIPVVMVRRPPIPAVAVVADVDRAIAWLLQQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWH6</accession>
    <name>A0A2G4EWH6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000143">
        <property type="protein sequence ID" value="PHX53895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53895">
        <property type="protein sequence ID" value="PHX53895"/>
        <property type="gene ID" value="CP500_019065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="14"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="157" mass="18035" checksum="80A039EFE3D98A3A" modified="2018-01-31" version="1">MTHSSTFSIEKTPLLLIVEDSNEDFEALQRFLRQSPRVVPIQRCVNGEQALAFLYRTGSYVDPESAPRPGMIVLDLNLPGIDGREVLRRVKQDKSLKTIPVVVFTTSNNPKDIEDCYQFGVNSYMIKPINFAQLKRDVQLLVDYWFEVTTLPDRLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWQ0</accession>
    <name>A0A2G4EWQ0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000137">
        <property type="protein sequence ID" value="PHX53951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53951">
        <property type="protein sequence ID" value="PHX53951"/>
        <property type="gene ID" value="CP500_018770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="632" mass="70780" checksum="AA8B232D9D1B56E5" modified="2018-01-31" version="1">MFLASSTKPIDSNLSAIVEQIEQQNPGLSVLAARQFRCAKRQTPLEVTISEPRKFNVLEEFILRACIEFVPAPTLKELADLLGLDEVFVKTTATTLVSLDILEVSGMDKIAIAPGGREFCDLGAVSKSQIQSIYAISDPLNQTLTFKFDSLRTETIDLPDLADLILLEHKIADISNLSITEIQPLIQDSGLGIHIPADGKIVTKCDVVGDDLNIWQTVSIFVLFDAIENQTNIQVRQGKQILETASNLLNELESQQKLSLNDLCKLTEDIILQEQEIILTKKNQEVATRLEKIQAEALNIVKATQTNSETNTSPSTTETGTVIFLRDSEIRQDFLNTIKSAQQNIFIYSPWVTSEVVDSEFIKILQNRADSGVWTAIGHGIARKQEEEDRPVPPELEDKLRQVKTPEGLSAVQIFWLGNSHAKEVIVDGKIHLSGSHNWLSYRGDRLPRGETTCKVTIPDLVKEAKEYMANRFQSRALQVWKEALINKDITIAEKSFSLWGALGMEAEALEQLQQENWLELYSMWLKLVCQGLRSKQLSPLSDCLGEALDLLSQISAEDADIERLREGWQQVVGAIAILDQTTAVTLLNEEYWAEFVRLGIAEESVNSPEEFISKYSSYKARKQPVKKKTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWR0</accession>
    <name>A0A2G4EWR0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2281 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000135">
        <property type="protein sequence ID" value="PHX53973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53973">
        <property type="protein sequence ID" value="PHX53973"/>
        <property type="gene ID" value="CP500_018645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018739">
        <property type="entry name" value="DUF2281"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10047">
        <property type="entry name" value="DUF2281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2281" evidence="1">
        <location>
            <begin position="6"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8531" checksum="47D3F796B4737007" modified="2018-01-31" version="1">MTIDLEIFQTVVKMPESLKQEILHYAKYLLEKHAKTESSPEQLEQPHGYGSWAGQIVMSDDFDEPLEDLKEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWW1</accession>
    <name>A0A2G4EWW1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Low temperature-induced protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000130">
        <property type="protein sequence ID" value="PHX54042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54042">
        <property type="protein sequence ID" value="PHX54042"/>
        <property type="gene ID" value="CP500_018275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013801049" evidence="2">
        <location>
            <begin position="37"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12509" checksum="334A7B0F9021847D" modified="2018-01-31" version="1">MSFINFNLPVSRLVRSLITVCFCALLFVSNAFPALAITSSPTKGTDQLLGIEKEAQKAVLKDPMSMEETQKKANEGINEIQGDADSEKMKNPSNTNATSFEQQVRKAVSNIKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWZ0</accession>
    <name>A0A2G4EWZ0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="4">AGPR</shortName>
            <ecNumber evidence="4">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="4">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">argC</name>
        <name evidence="7" type="ORF">CP500_018270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000130">
        <property type="protein sequence ID" value="PHX54041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54041">
        <property type="protein sequence ID" value="PHX54041"/>
        <property type="gene ID" value="CP500_018270"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="6">
        <location>
            <begin position="8"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="352" mass="37721" checksum="926792C68793CF01" modified="2018-01-31" version="1">MGNVGRVPVGIIGASGYGGVQLVRLLADHPAAEVVYLGGDSSAGKPYSSLYPHLTNCVDLTVEAIDLDKIAAKCEVVFLSLPNGLAYQMAPTLIEKGCKVLDLSADYRFENLDTYKAWYGGDRSDSALAATAVYGLPELYRDRIKNAQLVGCAGCYVTASLLALAPLLKQGIIVPETAIIDAKSGSSGGGRKAEINLLLAEADNSIGAYGVGRHRHTPEIEQVCSDLAGHDIKVQFTPHLMPMVRGILATVYANLRDPGLVREDLITIFSAFYRNSPLVKVLPAGVYPQSKWACGTNLCYIGVEVDPRTDRVIVMSAIDNLIKGQAGQGIQCMNLMMGWEETLGLPQLAFYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX37</accession>
    <name>A0A2G4EX37_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006632408.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000132.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54010">
        <property type="protein sequence ID" value="PHX54010"/>
        <property type="gene ID" value="CP500_018415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="15008" checksum="E4D419B975D66352" modified="2018-01-31" version="1">MEYLYYIANTSLTLRVVDYLRTAHHLPLQFITVIHQIDGWVVKVKMSQYLTPEMHGDFRAFMNELGIPYDPEIRLQMALWSLETGQSPLSVMRRYQVAVVCHGSPDRKEIEAFRQQFVKGLGYCPETLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX60</accession>
    <name>A0A2G4EX60_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000124">
        <property type="protein sequence ID" value="PHX54111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54111">
        <property type="protein sequence ID" value="PHX54111"/>
        <property type="gene ID" value="CP500_017885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011392">
        <property type="entry name" value="Tellurite-R_TerY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020634">
        <property type="entry name" value="TerY_vWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="18"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="220" mass="24621" checksum="96787A9044EDD0BB" modified="2018-01-31" version="1">MRLDEAVEFAENPEPRCPCVLLLDTSGSMQGAPIDALNEGLQTFRDDLIKDELAKKRVEVAIISFDNHIKVVQDFVTADQFETPLLKAQGQTHMGGGIQQALDLIAARKSEYRNNGITYYRPWVFMITDGEPQGESDDVVEIASQRIKEEENNKRVAFFAVGVEGANIARLAQIVERTPVKLRGLDFREMFIWLSASMQRVSQSKIDEQVALPPPGWGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXC0</accession>
    <name>A0A2G4EXC0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017530</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000117">
        <property type="protein sequence ID" value="PHX54185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54185">
        <property type="protein sequence ID" value="PHX54185"/>
        <property type="gene ID" value="CP500_017530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="10"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="377"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="411"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="445"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="479"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="513"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="547"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="615"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="649"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="733" mass="81296" checksum="B8976327D73B7CD2" modified="2018-01-31" version="1">MIGQLLDRRYRIIKVTDSSEVGTTYLAVDTHRPGSPQYQVIKMRLPDKSSQIPESVRAIFQRNAQKIEKLGKHNKIPELLAYFEGSRNLYLIEELITGKALSKELIPGQPWAENKVVDLLKEVLEVLVFIHENGLIHGRIQPDSLIRRQSDGKWVLTDFSLDRELNPEIADCYLCLPTSFNSVKWSFAKKQSAVAKTVYTPIEQSAGNLRYNSDIYAIGAIALRAVTGLSTLELAGLKNHKGEINIGDRVTCSVALADIIEKMVRSDFEERYQGATEVLADFKKIRAKIKVEPPLPTTTTSAMSQPPLKPSQIILLSIAGTFSALILTAGLIYYWQTQDPVRSQELFVRSQQKVLAGDKTGAIAHNSKPIALNASDAEAFYKRANASYDLGAREQAIQDYTQALQVNPSHSKAIYNRGIARCDLGNHRVALEDFTQAVRLNPSDANAYYQKALANYDLSDYRAAIEDFTQAIRLAPNDAIAYSNRGLARSAAGDKTGAMADFTQAIQISPEDAGVYYGRGRSRFNMGDYRGAMADYTKAIELAPDQADAYTNRCNVYLNLATYDKAIEDCTQAITIDPKDEDAYNNRCIAYLNLKQFQKAGQDCSLTIALNGNNSKAYSNRGLAREGSGDKAGAIADFTQAIRLNPSDAVVYSNRGNIYSELQNYTLAVEDFAQSVKLNPNNAKAFYSRGLVRRQLKDRNGAIEDFQKAATLFIEQGKADDFQNAQVQINDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXJ5</accession>
    <name>A0A2G4EXJ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54196">
        <property type="protein sequence ID" value="PHX54196"/>
        <property type="gene ID" value="CP500_017445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013908583" evidence="2">
        <location>
            <begin position="25"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="284" mass="32669" checksum="C8B1FAB3FB72531E" modified="2018-01-31" version="1">MKFRKILAPAVVLAILSVASPVLAQPLTDNFTALVQVGNIPARNLLSSPLMTLMGKFLGVFIGTATFILGSKTYKREQKWKYREFAAQTIKAFEEKLETVNVRKMLNSESQLIDLFPTASHPSNRFIYIDDQTLIKSLENQKDYDEKLQEAQIKYQRELENNNDYPRRKEPKLIQAAIRDNFRSFAESLQLLEAMIQSELVTEDELKPYLKPLFEMIDQASKRELDESSESERCSNILTYLGLDEKQTEPTTVQKSVKSLAARYQPTRLSVKFKKFLKNAFINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXJ9</accession>
    <name>A0A2G4EXJ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000119">
        <property type="protein sequence ID" value="PHX54170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54170">
        <property type="protein sequence ID" value="PHX54170"/>
        <property type="gene ID" value="CP500_017610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="262"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="506" mass="56976" checksum="6D073584DC50720C" modified="2018-01-31" version="1">MQEEISILIQAQYPLIYLVTSEEERCEQAISAIAKANKPQGRVFVWTVTQGMIEYGQPRTNQQSTLSPQAAIEWAIRQREPNDNVSIYIFKDLHPFKDDATVTRLLRDAIASFKGTHKTIILMSPLQQIPIELEKEVVVLDFPLPDMKELNQVLSSQLEQTKSRRITTEGREKLLKAALGLTKDEAEKVYRKAQVCKGRLTEDEVDIVLSEKKQLIRRNGILEFIEEDETIEAVGGSEALKNWLRQRSNAFTERAREYGLPQPKGMLIMGVPGCGKSLIAKTTSRLWGLPLLRLDMGRVYDGSMVGRSEANLRNALKTAELISPAILFIDELEKGFAGGPGSADSDGGTSSRVFGSFLTWMQEKTSPVFVMATANGVNRLPGELLRKGRFDELFFVDLPTKEERQDIFKIHLSKRRMDISRFDLEQLSNVSDGFSGAEIEQGIVAAMYEAFAQDREFTQLDIIAAIKSTMPLSKTMTEQVSALRDWARQRARPAASSVAEYQRMEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXT6</accession>
    <name>A0A2G4EXT6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system HicB family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000110">
        <property type="protein sequence ID" value="PHX54296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54296">
        <property type="protein sequence ID" value="PHX54296"/>
        <property type="gene ID" value="CP500_016910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031807">
        <property type="entry name" value="HicB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15919">
        <property type="entry name" value="HicB_lk_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HicB-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7512" checksum="E742F76F3D8C0783" modified="2018-01-31" version="1">MRYAIAIERAESNYSAYVPDLPGCVATGATIEEAEQQIKAAILFYLEQLRQSGASIPEARTLCKYVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXX3</accession>
    <name>A0A2G4EXX3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016475</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54382">
        <property type="protein sequence ID" value="PHX54382"/>
        <property type="gene ID" value="CP500_016475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="158" mass="17674" checksum="7669607B1A185297" modified="2018-01-31" version="1">MILDLPDAEATHKLGVTLGRSLPAGTIILLEGDLGAGKTTLVQGIAEGLEIPDSIESPTFTLINEYLSGRIPLYHLDLYRLETEEVEGLHLESYWDGLEMDLGIVAIEWAERLPYKPDNYLQICLSYYDHGRQIELIGDPQLLDWLLQSMISIPVVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXY7</accession>
    <name>A0A2G4EXY7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">tsaD</name>
        <name evidence="8" type="ORF">CP500_016300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54404">
        <property type="protein sequence ID" value="PHX54404"/>
        <property type="gene ID" value="CP500_016300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="23"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="134"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="359" mass="37959" checksum="9FFB2546F3D6A39D" modified="2018-01-31" version="1">MATVFAIETSCDETAAAIVKNRQVCSNVVASQIKIHQQFGGVVPEVASRSHLEMINQVIVQCLAEANLTWSEIDGIAATCAPGLVGALLVGLTAAKTLAIVHQKPFLGVHHLEGHIYASYLTEPDLQPPFLCLLVSGGHTSLIHVKDCGVYETVGHTRDDAAGEAFDKVARLLQLGYPGGPLIDKLATVGNPTAFKLPEGKISLPEGGFHPYDSSFSGLKTAVLQLVQKLKKENNHFGSEGILPESVINDIAASFQESVAKSLTKRAIACAVNLGLNTIAIGGGVAANSGLRQHLQAAAAKHNLRVLFPPLKYCTDNAAMIACAAAEHLQQGHTSPLTLGAHSRMAISDVMQLYNLNID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXZ3</accession>
    <name>A0A2G4EXZ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54403">
        <property type="protein sequence ID" value="PHX54403"/>
        <property type="gene ID" value="CP500_016295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="168" mass="18264" checksum="3233F887EE612464" modified="2018-01-31" version="1">MTPAGALDAAYRESLAEIKTDFYSESHPQGLMSHSTISLTDNNHSQDSFSSDNHSENFVEFSAKSSSTHSGAITEDDNNSVRFVGDQVYWHGYAWGQAGTVDGHKFYRDGHYIGRLGADMNVYDADAHKIGYVTPSGKAYTTDDKLFATGGTARWAAATLVFNSCSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY52</accession>
    <name>A0A2G4EY52_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Translation initiation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54416">
        <property type="protein sequence ID" value="PHX54416"/>
        <property type="gene ID" value="CP500_016150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="8381" checksum="9F2D77F5143DE3C8" modified="2018-01-31" version="1">MVDSFLRKIKDAIVGSEDENPAASEDENNYGHPPGSGQFGNVRPASEDPYGDPADEQFGNVRPASEDPYGDPADEEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYC3</accession>
    <name>A0A2G4EYC3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Photosystem II reaction center protein T</fullName>
            <shortName evidence="9">PSII-T</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">psbT</name>
        <name evidence="11" type="ORF">CP500_015955</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Seems to play a role in the dimerization of PSII.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the PsbT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54478">
        <property type="protein sequence ID" value="PHX54478"/>
        <property type="gene ID" value="CP500_015955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00808">
        <property type="entry name" value="PSII_PsbT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001743">
        <property type="entry name" value="PSII_PsbT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037268">
        <property type="entry name" value="PSII_PsbT_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01405">
        <property type="entry name" value="PsbT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161029">
        <property type="entry name" value="SSF161029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="31" mass="3438" checksum="31816B8F4B85F524" modified="2018-01-31" version="1">MESVAYILMLALALGVIFFAIAFREPPRIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYI6</accession>
    <name>A0A2G4EYI6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54589">
        <property type="protein sequence ID" value="PHX54589"/>
        <property type="gene ID" value="CP500_015230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="1">
        <location>
            <begin position="4"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="2">
        <location>
            <begin position="280"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="442" mass="47766" checksum="D922CAE56C5CF06D" modified="2018-01-31" version="1">MNFYLGIDFGTTGVRSTAIDSNGNIHSESQYNFTHEEPASELPSRWENALWAVIEQIPLAIRSQVRSIAIDGTSSTVMLCDTEGIPVCEPILYNDGRGVTVLDRLRAIAPANHTVLNATSSLAKLLWWLECEDTGRAGTGAPPLRRFFLHQADWLAFLLHGKLGISDYHNALKLGYDVANLCYPSWLTEGIAGVFKSSIAPILPQVVAPGIAIGPVTAQIGDRFGFPHDCIVCGGTTDSIAAFLASGVNSPGEAVTSLGSTLAIKLLSYTRVDDARYGIYSHRFTSPLQGGAGGGLWLVGGASNTGGAVLRHFFTDTELDYYSKQIDPKQESLLDYYPLLKKGDRFPNNDPNLLPRLEPRPADPVEFLHGLLESIARIESRGYELLQELGATPLTKVYTAGGGAKNLVWSAIRKRYLKVPVVTPVRTSAAYGSALLAMTVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYI7</accession>
    <name>A0A2G4EYI7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pcrA</name>
        <name evidence="10" type="ORF">CP500_015250</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54593">
        <property type="protein sequence ID" value="PHX54593"/>
        <property type="gene ID" value="CP500_015250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005751">
        <property type="entry name" value="ATP-dep_DNA_helicase_PcrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01073">
        <property type="entry name" value="pcrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="8">
        <location>
            <begin position="9"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="9">
        <location>
            <begin position="343"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="700"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="704"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="782" mass="89355" checksum="61C8627EB7A77A8E" modified="2018-01-31" version="1">MTQTTDFLSTLNPSQRQAVVHYNGPLLVVAGAGSGKTRALTYRVANLIRTNRVDPENILAVTFTNKAAREMKERIEKLLATQQAEAEYGKPLEELALDVQTKLRSQIYRNITKHIWMGTFHSLCGRILRYDIEKYQDEKGRQWKRNFSIFDESDAQNLVKQIVIKTLNLDDKKFDPKKVRYVISNAKNKGWSPQEYLLAEPDYRGRVIADVYTRYQDALAANNALDFDDLILVPVQLLRQNEQVLNYWHQKFCHILVDEYQDTNRTQSDLIRLLVTNNADPKDFDKWQNRSIFIVGDVDQSIYSFRMADYTILLEFQADFGDGLSDEKTQTMVKLEENYRSRSNILEVANHLIQNNTERIDKVLRATREPGAPITIWRADNEIDEAEFVAGQIHTLKRQNSEFEHGSNFAILYRTNAQSRSFEEALMRLDIPYNIVGGLKFYDRKEIKDILAYLRTLANPDDSVSLKRIINTPRRGIGDTTFGKIEDAATQLGIPLWEILKNESDVNTIAGRSAKAMIKFAEMIARWQSQVETLPASQIVKGIIEDSGYIDDLKNQGTEEAENRIANVRELYNAVLQFEEQNEEATLTGFLSKASLSSDLDDLQEGDSRVSLMTLHSAKGLEFPVVFLVGMEQGLFPNFRSLDDPRAIEEERRLCYVGITRARELLFLTHTRERRLWGGFREHCTPSLFLGELPPEFIAGSSRKTKAGKTNSSASNSRRSQQSQNLQLIDWKAGDRVVHPTFGLGEITHVLGEGEKVNLAIKFSGLGRKIIDPRNSQLQRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYN7</accession>
    <name>A0A2G4EYN7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54606">
        <property type="protein sequence ID" value="PHX54606"/>
        <property type="gene ID" value="CP500_015115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="29"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="22291" checksum="EBE364AFFFA6B0DF" modified="2018-01-31" version="1">MTATLEKLDRLDEPILIDGLSWRDFKLVEQLLSRPGVRLSFLDGVLEIRRITGEKHETIKERIGSILDLYLLQMGIDYQPTGSMTLESPSGLVKREADKSYKLGANRERPDLVVEVVVTSGGIDKLEAYKRLQIPEVWFWENGVLRLYSLGDNGYMEVDRSFVLPQLDIVLLALCINIENHLQAMREFRQAIQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYQ0</accession>
    <name>A0A2G4EYQ0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54307">
        <property type="protein sequence ID" value="PHX54307"/>
        <property type="gene ID" value="CP500_016870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="92" mass="10820" checksum="91DDBD89718CFA28" modified="2018-01-31" version="1">MSYLAQDPAQATKISQESEQETEWEFAEIWADTLISPPYILMLVKEKSGKFSIHNPAQNYQVIFSSNNYEDAKMWLLEDEYERLNSRILQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYQ3</accession>
    <name>A0A2G4EYQ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54616">
        <property type="protein sequence ID" value="PHX54616"/>
        <property type="gene ID" value="CP500_015165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="12949" checksum="88A0E4B6DFAE3DC9" modified="2018-01-31" version="1">MEKVEKYRDCIKQVLTKYAAYKPSYGEVEMQVIFDTEHNHYQVVRVGWDNKQRVYGCPIHLDIKDGKIWIQQNGTEIDLGQELVNIGVPKSDIVVGFHPPYMRQFTEFAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYU4</accession>
    <name>A0A2G4EYU4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54670">
        <property type="protein sequence ID" value="PHX54670"/>
        <property type="gene ID" value="CP500_014900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="151" mass="17794" checksum="59F2A3557B96B4F8" modified="2018-01-31" version="1">MPPKAHIESHLTAEELKIRYRQAENTTESRRWHLLLLVSRNWTIKQAAQVIGINYDYAKEIVQRYNREGPNSVKNRSRDRQPPPAKSLLNPEQQEELRQALQGLAPDGGIWTGPKVARWIAEKTGKAHVWPQRGWDYLSRLGVDWRRRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ14</accession>
    <name>A0A2G4EZ14_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54736">
        <property type="protein sequence ID" value="PHX54736"/>
        <property type="gene ID" value="CP500_014435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="28"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="30545" checksum="09BF015742DBED4F" modified="2018-01-31" version="1">MYSQLRNSRVKLSLGHIFWHEVGLGPNLVFLHGSWDNSNQWLRTIEYLYPDYHCFAPDLLGFGDSEHPKMNYSIDLEVECLAQYLDTLNLRQVYLIGHSLGGWVATSYALKYPDRVQGLVLLAPEGVNTSLPGRWQEARWLTAQPPVAYWLLRSIYPIAKWFGRQTKIEELLMFRKQLIDSQVAIKLLFRRREAEIKAELVDEKLSGLKTPLLLLQDSQNKADASSSLCQSYAALAGNAEIQFINSGGTNLPLESPDLVAKYIREFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ32</accession>
    <name>A0A2G4EZ32_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Bifunctional folylpolyglutamate synthase/dihydrofolate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_014330</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54756">
        <property type="protein sequence ID" value="PHX54756"/>
        <property type="gene ID" value="CP500_014330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="6">
        <location>
            <begin position="41"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="5">
        <location>
            <begin position="283"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="427" mass="46797" checksum="4F21435C3B684F9F" modified="2018-01-31" version="1">MNASSLLQSYQHFGVHLGLERIKQLLEKLDNPHQKVPIIHIAGTNGKGSVCAYLSSILTEAGYRVGRYTSPHLIDWTERICINQKPISPTELQQCLERVVSAAENDTETPTQFEIITAAAWLYFAEQKADIAVIETGLGGRLDATNVCENPLVSVITSISLEHWQILGPTVADIAGEKAGILKSKCPAIIGELPEFARIVIEKRIQKLDCPAIWVKPARDLGQGLAEYQLNQNGVKVRYELPLLGKIQLMNSAIAIATIQTLQNQGWKISQTAIKNGIAKTQWPGRLQQTTWKNQTILIDGAHNPAAAIALREYVDNFHNYQPINWVVGIIATKDSDDILTALLKKGDRLYLVPVPDQNSTPPAELAILAQNICPELTLCQTFPDLTTALDDAVADANLTVICGSLYLIGYFLQQQASPLHSASICG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ53</accession>
    <name>A0A2G4EZ53_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54805">
        <property type="protein sequence ID" value="PHX54805"/>
        <property type="gene ID" value="CP500_014150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="28"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="396" mass="45476" checksum="55B9D19F690D997D" modified="2018-01-31" version="1">MRLDIFKYVSNKGLSNEWRVEECRLSQVNLIVGKNASGKSRILKSIHLLSQLLSDDNIEAHNDEWHLYFDIDRPESQTEYILKIEKGLVVQEKLIMYGEGNEPLLLERDRSGEGTIFAKELNQKIKFQTPKAELAAVRRRDSIQHPFLEKLYQWSNSLSFYEFGTQLGKNFMTLMSYPTIKLSDNKRELKSYNSVVSIFQVGKLEIGDKFIQSIISDMKEIGYNLSEIGTKIPSTIERKFSTYNTLDGDGLPEFIYVKEEDLNFVTEQSDISQGMFRALSLLIQINYSLLASKPSCIVIDDIGEGLDYQRSSSIIKILIQKAETGLAQLIMTTNDEFIMNGVPIEYWSVIERTPGSAKLHNIYNSRDKIEEFKFIGLNNFDLFTSEFILEKISNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ85</accession>
    <name>A0A2G4EZ85_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54810">
        <property type="protein sequence ID" value="PHX54810"/>
        <property type="gene ID" value="CP500_014180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="11940" checksum="BF32902E4B68C518" modified="2018-01-31" version="1">MLQIIQENLSFSVSGVANRIFIMGEDSFELIIYGEFINPSVTLIFKEKEMSKSSSEEIGKKIAIGSAVAVGSLMVLGSIGSLVTANPVPVAAALKTAGAMLGFVGAGASGGSRRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ89</accession>
    <name>A0A2G4EZ89_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54798">
        <property type="protein sequence ID" value="PHX54798"/>
        <property type="gene ID" value="CP500_014110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="461"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="47"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="493" mass="53612" checksum="EE0D8A2C85CC71F4" modified="2018-01-31" version="1">MEVYCTRPGCPHPQNYFPDLEDSALLKTVQQRYCKSCGMPLILSGRYLPVRLLGQGGFGAAFLARDRHTPAMRQCVAKLLQPSVTLTPAQLRIAQNLFEREAAVLEELGNEHPQIPSLLAFFELTVPSLQGGKNDQFFYLVQEFIDGENLEQELAVKSKFLESEIMVVLREILKVLDFVHSRGSIHRDIKPANIMRGKNGRLYLLDFGAVKQVTQSAGSGKASTGIYSLGYAPPEQMNGQEVYPATDLYALAVTCITLLSGLQPTELFDSYRNEWNWHSRVQISSRLREVLDRMLLSAPSQRFQSTAEVEAALKPGSQPPSQPPTVVVAPPQITTQPPLTHTSYPPTPQTSQPPTIIPGTPSGGLQASPRGAFSIWEVLSGAAFTGFEGGLLAIALTSLLPSPGLSMGLLGMIVGGLIYAQYRRSIEQTEMLIIGAGTLALLIFFPALRSAALAIYPGSPITGVLFVGWLAALGAIAATAIFRLIYKLLSNVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZB2</accession>
    <name>A0A2G4EZB2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_013820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54855">
        <property type="protein sequence ID" value="PHX54855"/>
        <property type="gene ID" value="CP500_013820"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer4_20" evidence="6">
        <location>
            <begin position="23"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="154"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="494" mass="54212" checksum="9DB7C7B157459366" modified="2018-01-31" version="1">MGKPTGFIEFLRELPSELSPVERVHNWDEFHLPMDEDKLRTQGARCMDCGIPFCHTGNLISGMASGCPINNLIPEWNDLVYRGLWKEALDRLHKTNNFPEFTGRVCPAPCEGACVLGINNPPVTIKNIEASIIDKGWDEGWITAEPPAKRTGKNIAIIGSGPAGLSAAAQLNKAGHWVTVFERADRPGGLLMYGIPNMKLDKEQVVMRRLKVLEDEGVKFICNTEVGKDLPVEQLLKEFDSVVLCTGATKPRDLGIEGRELKGIHFAMDFLTANTKAVLDKNTNDNFIWAAGKDVVIIGGGDTGTDCVGTSIRHGCNSLVQLEIMPKPPSERAANNPWPEWPKVYRLDYGQEEAAAKFGDDPRGYLTTATKFEGDENGNVKAVHTVEVEWAKNEKGQFIPKHIPGTEKVLPAQLVLLAMGFLGPEQPLLDAMGLERDARSNVKADHEKYTTSIPGVFAAGDCRRGQSLVVWAINEGRGVARECDLYLMGSTDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZH2</accession>
    <name>A0A2G4EZH2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Magnesium protoporphyrin IX methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54909">
        <property type="protein sequence ID" value="PHX54909"/>
        <property type="gene ID" value="CP500_013555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046406">
        <property type="term" value="F:magnesium protoporphyrin IX methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010251">
        <property type="entry name" value="Mg_prot_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010940">
        <property type="entry name" value="Mg_prot_MeTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07109">
        <property type="entry name" value="Mg-por_mtran_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02021">
        <property type="entry name" value="BchM-ChlM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51556">
        <property type="entry name" value="SAM_MT_MG_PIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mg-por_mtran_C" evidence="1">
        <location>
            <begin position="131"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="25113" checksum="C3556977B670D6C9" modified="2018-01-31" version="1">MNLVNDKDIVKQYFNSTGFDRWQRIYGDGKVNKVQLDIRTGHQQTVDTVIKWLEADGNLRGLCVCDAGCGVGSLSIPLAEAGAIVCASDISEKMVAEAYERATAVPGKLYNISFAAQDLEALSGKFDTVICLDVLIHYPQSKVADMIAHLSSIAQSRLILSFAPKTLALTALKKFGELFPGPSKTTRAYQHREADIIKILESNGFVIKRTAMNSTSFYYSRLLEAVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZI1</accession>
    <name>A0A2G4EZI1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CO2 hydration protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54921">
        <property type="protein sequence ID" value="PHX54921"/>
        <property type="gene ID" value="CP500_013460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010220">
        <property type="entry name" value="CO2_hydration"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10216">
        <property type="entry name" value="ChpXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01964">
        <property type="entry name" value="chpXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="388" mass="44094" checksum="6F993C044CD78DF0" modified="2018-01-31" version="1">MKNTILKPSSHPLAEYIDLLESGKALLPESDENVVEVIGVLKSYAIVLDAYSRNLNYIAESQFLVLFPFFKYFNGEVTLPKLMRYLWHDRINFEYAEYCMKTMLWHGGGGLDSYLDSPEFDNLVEKAIAAKLKGNIFMQGLHKVFPNFLPEQVRMLAYYTGLGQFWRVMSDLFMDLSDSYDRKETKSIADVVDFVKAGLVAAASLPITYSVKISDRVYDIIPAAANLTFLPDVAVPYVESIFFRGTAFFGTVSYNAQAHQIPAEQRDFTYGALFADPLPIGGAGIPPTQLMQDMRHYLPEYLHEVYRTSCRGEDDVRVQICQSFQKSMFCVTTATILGLAPHPINTSDSDEKKANRVYLEGWMDRFGNSRLNWANQPTNRSCQLFPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZK2</accession>
    <name>A0A2G4EZK2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phytoene synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54933">
        <property type="protein sequence ID" value="PHX54933"/>
        <property type="gene ID" value="CP500_013325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="309" mass="36059" checksum="EF8F2ED5288E680B" modified="2018-01-31" version="1">MLQLSKLQCMRTLASLDESYELCRQVTASYAKNFYLGTQLMPEAKRRAIWAIYVWCRRTDELVDGPGSEATTPETLNLWEKRLESVFAGHPHDDYDVALVDTLSRFPIDIQPFREMIAGQQMDLYRSRYETFEELNLYCYRVAGTVGMMSMSVMGVDESSPATNWNWHWCNQIPKEEAISLGIAKQLTNILRDVGEDARRGRIYIPLEDLALFNYTEEDLFNGVIDNRWRELMRFQIQRARKLYTSAEPGIKVLSPDIRWTVWAATMLYSRILNAIERNNYDVFQKRAYVTNFQKLQCLPAAWIKSKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZQ6</accession>
    <name>A0A2G4EZQ6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable molybdenum cofactor guanylyltransferase</fullName>
            <shortName evidence="4">MoCo guanylyltransferase</shortName>
            <ecNumber evidence="4">2.7.7.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GTP:molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Mo-MPT guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdopterin-guanine dinucleotide synthase</fullName>
            <shortName evidence="4">MGD synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mobA</name>
        <name evidence="6" type="ORF">CP500_013295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin guanine dinucleotide</text>
            <dbReference type="Rhea" id="RHEA:34243"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:71310"/>
            <dbReference type="EC" id="2.7.7.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MobA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.77" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54992">
        <property type="protein sequence ID" value="PHX54992"/>
        <property type="gene ID" value="CP500_013295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061603">
        <property type="term" value="F:molybdenum cofactor guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02503">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00316">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013482">
        <property type="entry name" value="Molybde_CF_guanTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="5">
        <location>
            <begin position="8"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="210" mass="23284" checksum="6B3E764B3C289BF9" modified="2018-01-31" version="1">MTNDKISVIVLAGGKSSRMGRDKALLEIEGKSLLLRSCEVATNLTSEVYVLTAWPDRYRSTFSKKCQFMVEYNPGAGPLIALTQGLTQITTEWILLLACDLPLLDAQIIQHWASHLTAVPPSTLAVVPYQNSRWEPLCGFYRQQSLSSLQSFIEHGGRSFQVWLNQIAVVPLSVGEREAVMLSNCNTLEEFEQLNKLGMGNWESGIGHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZW4</accession>
    <name>A0A2G4EZW4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ftsZ</name>
        <name evidence="9" type="ORF">CP500_012850</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55050">
        <property type="protein sequence ID" value="PHX55050"/>
        <property type="gene ID" value="CP500_012850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 5 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="62"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="8">
        <location>
            <begin position="256"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="392"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="70"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="157"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="426" mass="44743" checksum="B3CC60060952AFAA" modified="2018-01-31" version="1">MTLNNRQGSDQDSPPSEEVKNFPVALDSTNPFRRKSGYVNVDSIDIDLMVNPKDIMPSSAAKIKVIGVGGGGGNAVNRMIASEVSGVEFWCVNTDSQALVLSNAPKRLQVGQKLTRGLGAGGNPAIGQKAAEESRDEVASALNGADLVFITAGMGGGTGTGAAPIVAEVAKEMGALTVGIVTRPFTFEGRRRTGQAEEGIAELKSRVDTLIVIPNDKLLSVISEQMPVQEAFRVADDILRQGVQGISDIITIPGLVNVDFADVRAVMADAGSALMGIGVGSGKSRAREAAMQAISSPLLEASSIEGARGVVFNITGGTDMTLHEVNAAAETIYEVVDPNANIIFGAVIDERLQGEIKITVIATGFSGEIPVQQRVSRTQNANAPWRAATVPVTPAQQTPAQNTQLKPKEDAGLDIPEFLRKRLPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZY1</accession>
    <name>A0A2G4EZY1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent DNA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55063">
        <property type="protein sequence ID" value="PHX55063"/>
        <property type="gene ID" value="CP500_012635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="1">
        <location>
            <begin position="154"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="425" mass="47268" checksum="DBB55AB8778B4673" modified="2018-01-31" version="1">MDCTEYAETKRKAAKKISADIRERWNNRIVQRELHLMGEAGAVQYLSDYGRGIGTAKVIGFALCAESEGYPEMAIGFWKRAFELETGEKPIALNTQNNATTNLAPGKKLTAAPKIETVNNLVVAELPPHLQPGRIVTMQPVDAPSERSYYIENPDYWGQPKRDGNRVVVIATKDKVYYQSRSTNLRQQPSIEIETALIETAAKIGTFVLDGELYYKSCRGSEHRTGAQAATVNIESGFPTVQPSAIYGIFKCLFFKGNDLTILAESERIAAGVEVGEMLASLCQAFETVPTFRTTAEKLLLANQQESENREGEVWVLHNCRYVGGKDVKKFSMVRTKYCQELDLFIVGLTATKVAGRPFSAIEVAQEIDGKLVPIGTVGTGFSGEEMQEIARRYEANRKNVKIKVRSQGLTESGKLWHARFLEFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZZ1</accession>
    <name>A0A2G4EZZ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55071">
        <property type="protein sequence ID" value="PHX55071"/>
        <property type="gene ID" value="CP500_012675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="193" mass="21375" checksum="18E13426E17C271E" modified="2018-01-31" version="1">MSVQPIESLSSTPIFEPALFRISPLIRITLLSLYAALTIPLPFLSEATSAPVSPNLIWAGIVVGAIGLYGVLSERVILNEEEIQVTYPNWFPKIFRKGWSLPWTEVKALKPRSTGQGGLVYYFLSHSGEGYLLPMRVAGFAKLVRLVEAKTGIDTTDVRPLSQPWMYLILLFCTLLLLLVDGWTIVTAIGLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F054</accession>
    <name>A0A2G4F054_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="2">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55133">
        <property type="protein sequence ID" value="PHX55133"/>
        <property type="gene ID" value="CP500_012160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004552">
        <property type="entry name" value="AGP_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00530">
        <property type="entry name" value="AGP_acyltrn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="3">
        <location>
            <begin position="46"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="212" mass="23172" checksum="BC1BBED7CDB611D3" modified="2018-01-31" version="1">MSKNREPVESLILYYLFKWSIVSPMLHLYFRGRIYGAENVPTSGPLVVVSNHASDFDPPILSSSMRRPVAFMAKEELFKVPILKQAITLYGAYPVKRESADRSAIRSAIQSLENGWATGVFLQGTRTADGRITDPKLGAALIAAKAKAPLLPVSLWGTHAIASKDSGLPRSVPLTVRIGNLIEAPSSSDRSELEALTQRCAQEINAMHDLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0B3</accession>
    <name>A0A2G4F0B3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55201">
        <property type="protein sequence ID" value="PHX55201"/>
        <property type="gene ID" value="CP500_012080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="33"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="14455" checksum="363AC549FAC7EE83" modified="2018-01-31" version="1">MPAHRKFIENINWEGAILQSTIQISLSQAEIAEFCQRWKILEFYLFGSVLRNDFRPDSDIDVMVKFAADAQWGFEFVEIKRELEKMFQRDVDLLTKTSIEESHNWIRRKEILGKAKLVYVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0C9</accession>
    <name>A0A2G4F0C9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_011830</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55222">
        <property type="protein sequence ID" value="PHX55222"/>
        <property type="gene ID" value="CP500_011830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017848">
        <property type="entry name" value="RNA_pol_sigma_RpoD_cyanobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02997">
        <property type="entry name" value="Sig70-cyanoRpoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="378"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="421" mass="48329" checksum="C91119F743A4792F" modified="2018-01-31" version="1">MPATSFYAEAEFDERLRVNPLQDDVLDEDAEEAGDELIDQDATETEDADRDAKLQKNANRRTTDLVRLYLQEIGRVRLLGRDEEVSEAQKVQRYIKLLELRNTAASQEEGKIQGFVHLIEVRDRLAAKLGHKPSLERWATTAGVTDVSEIKRIMSEGKRHWAELAEMSVETLEKTQAEGVEAKDHMIKANLRLVVSVAKKYQNRGLELLDLIQEGTLGLERAVEKFDPTRGYRFSTYAYWWIRQGITRAIATQSRTIRLPVHITEKLNKIKKAQRKISQEKGRTATIEDIAVELDMTPIQVREVLLRVPRSVSLETKVGNEKDTELGDLLETDSVSPEEMLMREALHRDLQQLLADLSSRERDVILMRFGLGDGHPYSLAEIGRALDLSRERVRQIEAKALQKLRQPKRRNRVRDYLESLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0G3</accession>
    <name>A0A2G4F0G3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4926 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55251">
        <property type="protein sequence ID" value="PHX55251"/>
        <property type="gene ID" value="CP500_011765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032568">
        <property type="entry name" value="DUF4926"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16277">
        <property type="entry name" value="DUF4926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9175" checksum="57806DDD2CCD1BBA" modified="2018-01-31" version="1">MINSTSKLLDVVALTVDLPQYNLWRGQVGTIVEMLADGAAFEVEFSDRNGRTYESVGLRPEQIMVLHFEPASPDIQYEMATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Q9</accession>
    <name>A0A2G4F0Q9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55349">
        <property type="protein sequence ID" value="PHX55349"/>
        <property type="gene ID" value="CP500_011155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="320" mass="31969" checksum="68605BA15F4ED08D" modified="2018-01-31" version="1">MTPTPTPTPVMIPIPTPVPIPIPTPVPTPTPANPTPSPTPMGNLTTGTSTGNLTNGTSTGNLTTGTSTQSIFTPVLIATPAISTPGAPGNPTGQPANTVSDGFYNLSDNNDNILLFSLPPVAAGKPIFALSGNDNITGTSGADTINGMQGADTIDGGAGNDSLSGGKESDFLDGGAGDDGIFGGNDNDILTGGEGNDTIRGGKDKDSLIGGNGDDLLYGDRNQDFLTGGSGNDRFVLAGGLVAATSLTDADVIIDFTAGDKIGLTDGNTFASLTFEDVSLNVNARLADINSTAIKVGSSYLGIVQGVAKDALTANVFVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F136</accession>
    <name>A0A2G4F136_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_010620</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55471">
        <property type="protein sequence ID" value="PHX55471"/>
        <property type="gene ID" value="CP500_010620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="165"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="292"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="397" mass="45278" checksum="DEBB8D498ECAF6A1" modified="2018-01-31" version="1">MIVLEFKLKGKPQQYRVIDEMIRTAQFVRNKALRYWIDNQAVKLVDLYKQCAIMAKEFEWARKLNSMARQASAERAIFAIQRFFSNCKAKKPGKKGYPQFKKHTHSVEYKTSGWALSTDKRCLTFTDGFAAGTFRLLGSRDLHFYAPKEIKRVRVIRRADGYYAQFCINVERTEEIVPTGKMIGIDVGLNHFYTDSAGETVPNPRHLRKSEKALKRLQKRVSRKKKGSSNRKKAINKLGRKHLKVSRQRKDFAIKTALYVVKSNDFVAYENLQVRNMVKNHKLAKSISDAAWSQFAQWLEYFGKVYGKTVVAVAPQYTSQDCSSCGNRVQKSLSVRTHICLCGTVLDRDHNAALNILAKGLKEAGISSNTVGHTEINAWGQTDLYSLVVTSMSKLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F137</accession>
    <name>A0A2G4F137_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55466">
        <property type="protein sequence ID" value="PHX55466"/>
        <property type="gene ID" value="CP500_010590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="16"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="11962" checksum="A956187AFF7FA123" modified="2018-01-31" version="1">MSDQFWNQVKSNYRLGQLIYGKVEHHAPFGIFVNIGDDTVRGLVQITDFVDSGDMTPEMYPDIGSPIGAVVVGYTEDDRHQVWLSVKPSVLQKALVQLKVPATSERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1K1</accession>
    <name>A0A2G4F1K1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_009810</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55618">
        <property type="protein sequence ID" value="PHX55618"/>
        <property type="gene ID" value="CP500_009810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="96"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="550" mass="62494" checksum="A2C809D630D29FBD" modified="2018-01-31" version="1">MNSQQSTVIRNWLTFPLILVLVIGIFFRFANLDRKFYWIDETYTSLRVSGYTEAEMLKQISYQQIISPSDLQKYQQINSEHDLSYTLHSLATEDPQHPPMYYILARYWAQWFGSSVTAMRSLAAVISLLVFPAVYWLAWELFESSAVAWMAIALFAISPYHILFAQEARQYSLWTLATILSTAALLRATRANEENQNLTRLLYHWTIYALMTIIGLSTHLLFVCVAAAHAIYITIIANWRNIKTFIAYYTATLVAFIISIPYLVNTVENFNQIRSTTIWAEQTNFLRLVTRWIGSVTIAFFDIGIDGSADGVLLVLLIPVSLIILALVGYAIYFVYQQTPKRVWLLILLLIATTALFLAIPDIIQGGRRSTNPRYLVPCYVGIQLAVAYLLSAKVSSNLDDFKQHKLWKTAIVALFTSGIISAGVSSQADMWWNKGSGWLRAELEVAKIVNEATNSLMISDANIAYIMPLSHRLEPKVQLLITPRCYTSCYQNQELALAKPTIPKIPNGFSEVFLYRPSSVLRSGIEQQNYQIDPIIGTVKLNLWKLTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1S1</accession>
    <name>A0A2G4F1S1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phycobilisome rod-core linker polypeptide CpcG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_009320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the phycobilisome linker protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55688">
        <property type="protein sequence ID" value="PHX55688"/>
        <property type="gene ID" value="CP500_009320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001297">
        <property type="entry name" value="PBS_linker_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038255">
        <property type="entry name" value="PBS_linker_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00427">
        <property type="entry name" value="PBS_linker_poly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51445">
        <property type="entry name" value="PBS_LINKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0793">Thylakoid</keyword>
    <feature type="domain" description="PBS-linker" evidence="6">
        <location>
            <begin position="11"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="253" mass="29279" checksum="F99FED13777299B0" modified="2018-01-31" version="1">MALPLLNYAPKSQNQRVAGYEVGGDEQPRIFTSENVLSSGDMENLIWAGYRQIYSEHQILKSNRQKSLESQLKFGQITVRDFIRGLATSSPFLERNYQTNSNYRFVEMCVQRILGRDVYSEREKIAWSIVVANKGPQGFIDDLLNSDEYLNKFGYDTVPYQQRRILPQRVGGEVPFNLKTPRYGEYHRSQLGFPQIIWQSTVRRFVPQELQRKAGDPSNYLDMARNMPRPATAPQRVPLANINIETMVPRRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1W7</accession>
    <name>A0A2G4F1W7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulphatase-modifying factor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55742">
        <property type="protein sequence ID" value="PHX55742"/>
        <property type="gene ID" value="CP500_009285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="313"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="68"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="570" mass="64262" checksum="BBBAD5D8483DE578" modified="2018-01-31" version="1">MRRKYVSNCLICQTEYVEATVNFCSTCGWDLSQDNVYVLGELPDVFVQNQQSQLAGARRIWSSFLANQERLNQEKADLSSQLTEQLTKLQEQLAKSRNLRRQIKAKLEQVTAQLTQKEQETPALQAEIAKLAGERAELVAQLAQANLGISRLEQVTRERAELFVQLAQSDAELHKLKQEHLVLVAQLAAAKTENSRLQSELGTQLAAAHTEIARLQSDLATQLSQSQTENARRQSIARERDELAAQLAKAHTENSRLQVGLEQQLVQWELVVGNHREFSFPVVILDRQGRENSRQNGTAQALIQALPGGIMLEMVAIPGGKFWMGSPDTELERTAAESPVHQVTVSPFYLGRFPVTQAQWAAVAGLPKVVRDIKANPANFKGKDLPVESISWYDAVEFCARLTEYTKLPYRLPSEAEWEYACRAGTTTPFHFGETISPKFVNYDGNYTYGEGKKGEYRQKTIPVGSLKIANAFGLSDMHGNVWEWCSDIWHENYNGAPVDGSAWDDLDKNHLINLRQKLNDNDNHSRLLRGGSWCRNPWHCRSALRSWYLSAYRDDSFGFRVACVAARFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F253</accession>
    <name>A0A2G4F253_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55822">
        <property type="protein sequence ID" value="PHX55822"/>
        <property type="gene ID" value="CP500_008685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="12049" checksum="6C49C41D46828B65" modified="2018-01-31" version="1">MNTQLMVKPSSLMPQGLKMVEFGNIYLFRFTDDLQSRMEELLERKKLDLLSADEIPELAGIIELSRIFTLINAQLSTKAKWCPIALDNLYDSELNISANTATLQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F258</accession>
    <name>A0A2G4F258_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA starvation/stationary phase protection protein Dps</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_008725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Dps family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55828">
        <property type="protein sequence ID" value="PHX55828"/>
        <property type="gene ID" value="CP500_008725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016722">
        <property type="term" value="F:oxidoreductase activity, acting on metal ions"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01043">
        <property type="entry name" value="DPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002177">
        <property type="entry name" value="DPS_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023188">
        <property type="entry name" value="DPS_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42932">
        <property type="entry name" value="PTHR42932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005900">
        <property type="entry name" value="Dps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01346">
        <property type="entry name" value="HELNAPAPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00818">
        <property type="entry name" value="DPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00819">
        <property type="entry name" value="DPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin" evidence="3">
        <location>
            <begin position="28"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="20257" checksum="1084A05C2ECA1877" modified="2018-01-31" version="1">MSLNNHKQRLYPTRIDMPAETRSNIVGLLNATLATTLDLKTQVKQAHWNVKGMDFYQLHLLFDEMATELDDYVDTVAERVTALGGFAVGTARTAAADSILPEFPFDILDGKDYVTALADRYAPYAQHLRVAIDKATELGDADTADLYTEISRTIDKRLWFLEAHLQGAATTATVAIPDKVAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F262</accession>
    <name>A0A2G4F262_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Molecular chaperone DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55836">
        <property type="protein sequence ID" value="PHX55836"/>
        <property type="gene ID" value="CP500_008780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="6"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="322" mass="36608" checksum="4669C1DB991AE9A9" modified="2018-01-31" version="1">MNDLDQYYKVLDLLPGATPEEITQAYKDLAFIWHPDRIPKDNTRLHKKAEEKIKEINQAREQLRSIQPRNQHQNTQQQHTQQQHTQQQHTQYQNSQQQHTQYQKTQYQNTQYQNTQYQNSQYQNSQYQNTQQQNTHYQNSQQQNTQHRNTQQPPPREPRYSSEAYSRSYGEKPTNPAGPYSDSSRYQSSTSSSSYRQTTQQKPDLSGSNFKGASLKEKDFSGRNLSNANLSQADLSDAFLHNINLTGANLQKANLFRANLLGACLINANLRETNLIGADLSGADLSGADLTGAKIGYGDRVMVKLTGARLSGTILPDGTVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F285</accession>
    <name>A0A2G4F285_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2656 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55859">
        <property type="protein sequence ID" value="PHX55859"/>
        <property type="gene ID" value="CP500_008475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020325">
        <property type="entry name" value="Uncharacterised_16.1kDa"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10847">
        <property type="entry name" value="DUF2656"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="158" mass="17447" checksum="524B043DE8FE3980" modified="2018-01-31" version="1">MTESGTGRMLLSHNFDIAEGVFPPLSREDLTLVFVDGLSQYPEIKCRQLNHAHWMVEVLFSTNDFAPPQVGEFCAEALVDKRKSQGKADDSFPDILILAGLKKTPPLSSDVEALQTGEWGVDVVETPSADSFLMAMGWDDKTAGKSIEDVFKVERRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F298</accession>
    <name>A0A2G4F298_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55903">
        <property type="protein sequence ID" value="PHX55903"/>
        <property type="gene ID" value="CP500_008385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="386" mass="44486" checksum="D5FA7A40F9D9EB88" modified="2018-01-31" version="1">MTDIHQIVTALEDKEYKEAAQLIKQLQTKSPENPWVKYYMARYYELTNNSEKAETTYKQILRDITNPKIISQARQGIQRIETAAQDRRKQAIETAKNDPSNLEPALLILEAVSPEDKAAAIQNISRIFKTDTYTTRMQIQSRGWRLYKTGPIAEIQIYGQELLNAGIPVFWGTLADIQKIQIFQVQHFQSLSSPAVVCKDTLDRLGSIAFNWSEVSQIVEGSLPIFIDVMDYSPHRRTEQFRHKEITQDYAQICDLHIPSRNCILRMCDQNYDFKQGVDFTKTLEDISTSANPKNPKSRSQKSQQIPQSTTRINWNHLLEILDQQLDVTLWSEFTPFAETVLDYTNMLSNIDAHIEIDRKSETPWDPAFQLYSGLAFLRNKSNSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2E6</accession>
    <name>A0A2G4F2E6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55918">
        <property type="protein sequence ID" value="PHX55918"/>
        <property type="gene ID" value="CP500_008050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="10471" checksum="FDADF998225B1F94" modified="2018-01-31" version="1">MADEAAKPAPMIFKGVCKDGVLKGKEIEGKLDIKINVESVKAVEQPKKPAPAWETNIFWVLFLLVANLAAGDPAGIRKYSPPHEPPSSSEMLNQSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2H9</accession>
    <name>A0A2G4F2H9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Glutamate synthase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CP500_007790</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55983">
        <property type="protein sequence ID" value="PHX55983"/>
        <property type="gene ID" value="CP500_007790"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015930">
        <property type="term" value="F:glutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="16">
        <location>
            <begin position="22"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="903"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX55983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1528" mass="166773" checksum="F35027285C03C678" modified="2018-01-31" version="1">MNNHGLPQKQGLYDPQFEHDACGVGFIVHVKGNKSHEIVEQGLTILLNLDHRGACGCEPNTGDGAGILMQVPHKFLKKAAAAQNIELPEAGEYGVGAIYSSRNQTERENGKRIFAEIAAAEGCPVLGWRDVPTDNSSLGDTAKASEPFMQQVFLARPAGMDEAAFERKLYVIRKRAHNAIRKTNVDPYWYNSTLSCRTIVYKGMLMPVQVGDYYPELHDPDMESALALVHSRFSTNTFPSWERSHPYRYIAHNGEINTMRGNINWMHARQSMFESELFGDDLKKIPNLINIEGSDSTIFDNALELLTLAGRSLPHAVMMMIPEPWTAHESMSDEKKAFYEYHSCLMEPWDGPASIAFTDGTSIGAVLDRNGLRPSRYCITKDDIVIMASEAGVLPIAPERIVSKGRLQPGRMFLVNTAEGRIISDDEIKHQIASEHPYREWIDQHMVEIAKLPDAEVVDASQPETLLQRQMAFGYTFEELRLLLAPMARDGVEAVGAMGADTPLAVLSNRQKLLYEYFQQLFAQVTNPPIDSIREEIVTSAETTIGSERNLLKPEPESCHLIELKTPILSNEELAKLKQVSEGNFKSVTVPILFDPKTGVKGLEQALEDVFDAADSAIASGVNILILSDRGINAENAPIPALLAVAGLHHHLIRQGTRTRAGLVLESGEPREVHHFATLIGYGCGAINPYLAFETIADSIRQGLLVNVDTKTASKNYVKAATKGVTKVASKIGISTIQSYRGAQIFEAIGLNKSVVNKYFTWTASRIEGVDLEVIAQEAILRHTHAFPDRPSSGHTLDVGGEYQWRKEGEAHLFSPQTIHALQQAVREGSYPLFQKYSALVNEQNQQHFTLRGLLQFKQRESIPIEEVEPVEAILKRFKTGAMSYGSISKEAHESLAVAMNRIGGKSNTGEGGEDPDRYTWTNDRGDSKNSAIKQVASGRFGVTSLYLSQARELQIKIAQGAKPGEGGQLPGKKVYPWIAKVRHSTPGVGLISPPPHHDIYSIEDLAELIHDLKNANREARISVKLVSEVGVGTIAAGVAKAHADVVLISGYDGGTGASPQTSIKHCGLPWELGLAETHQTLVLNNLRSRIAVETDGQLKTGRDVAIAALLGAEEFGFATAPLVTLGCIMMRVCHQNTCPVGVATQDPLLRKNFTGDPQHTVNFMTFIAQEVREIMAQLGFRTLNEMVGRTDVLEAKQAVEHWKAKGLDFSNILYQPEVGADVGRYCQMPQDHGLEKSIDLSVLLDLCKSAIEHGEPVKATLPITNVNRVVGTILGNEITKRHWEGLPDDTVHLHFQGSAGQSFGAFVPKGVTLELEGEANDYLGKGLSGGKIILYPSQASTFVAEENVIVGNVVLYGATSGEVFIRGLAGERFGVRNSGVNTVVEGVGDHGCEYMTGGKVVVLGATGRNFAAGMSGGVAYILDEAGDFATRCNMSMVALEKLEDVEEIADLQQLIQTHFDLTGSAIASQVLANWDAMVPVFVKVMPRDYKRVLEAIERAIAAGLSGDDALTAAFEENARDVARIGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2M1</accession>
    <name>A0A2G4F2M1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56011">
        <property type="protein sequence ID" value="PHX56011"/>
        <property type="gene ID" value="CP500_007595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="123"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="311" mass="36399" checksum="D8EF572FE6847F70" modified="2018-01-31" version="1">MKNHQLLDKGKTPLNFLFRLLHKTKTIYLILIFLISIGISGWTVEAYFVRIPIFGFHNIVDMQNPADLPPRRRSFPTDYSKQNLAIFLEYLVQQNYWFLSSQDLYTYFINKSKPVPPEHQGQKPIMITFDDGYKGVHTNALPIIEKLSFIYKEKGKFVLFVNPHFLGVDMGKAFLPHTTCNDLREGYKKGFYDIQSHGFTHKNLTTLSGKKLEFEIAKSKSVLRKCMINLDKNKLVGAHIAYPYGASDWEVESILPKYHLSGFLYDNNLLRVSRLRNNYRISRMTVNKDMLPTYLIRIAERSSTLRKKRWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Q9</accession>
    <name>A0A2G4F2Q9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sterol desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56051">
        <property type="protein sequence ID" value="PHX56051"/>
        <property type="gene ID" value="CP500_007410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="425" mass="47413" checksum="2979E8B163E0D057" modified="2018-01-31" version="1">MVNYWIVGALAIASVCWAEIIRDFYHVASHYWPPLYKLHAWHHRVFRPNLTPVSETIYKQAHWRNDVPEAASMMVLGLLLWVAAYFGMPEYHWGAAAGCVYTLGFLLSAIARGCGIKGADELTDITHQPGNFLTPPGNWFVNKPYHWKHHFDNQNAYYCGTFTLIDKLMGTALSLKGKTVAVTGASGTLGHLLLKHLHKAGAKVIALTSGNQTITLNIDGENLPIKTITWQIGQEADLAKLLEKVDILVINHGINVQGERTPEAIAKSYEINTFSAWRLMELFLLTVRTNENIANKEVWVNTSEAEVIPAVSPLYELSKRALGDLVTLRRLDAPCIVRKLILGPFKSNLNPIGIMSPDWVAQQIVNQAKADARNIIVTINPLTFILFPVKEFFVSLYFQIFSRKAISGIKAEMTPEKSSVGAKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2S9</accession>
    <name>A0A2G4F2S9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase subunit sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_007520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56071">
        <property type="protein sequence ID" value="PHX56071"/>
        <property type="gene ID" value="CP500_007520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="49"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="156"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="219" mass="25460" checksum="CFE1043C294E6EE6" modified="2018-01-31" version="1">MNEFTSLSWSAVVATVSQVQLPAEKLSNYDLVLRCQEGNRPESAAFSELLKRYQSHVDRVLYHLAPDWQDRADLAQEVWIRVYRNVNRLQEPVKFRGWLSRIATNLFYDELRKRKRVRTPLSLDVPRCLEDGEVDWEIPADSPGPDEDLTTREFYDQLRVAIADLPEVFRTTIVLREIQGLAYEEIAEMTGVSLGTVKSRIARARQRLQLQLQKYLDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2W5</accession>
    <name>A0A2G4F2W5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56096">
        <property type="protein sequence ID" value="PHX56096"/>
        <property type="gene ID" value="CP500_007260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="10"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="189" mass="21545" checksum="BE1393D04E403EF8" modified="2018-01-31" version="1">MTVASQKMSLEEYLNFDDGTETQYELDNGELIVSPPESDLNRRIGSFLLTLFFQLGIPTYRLRIGTEIVVLGARATTRFPDLMVLSEELATALEGSRRSTIMMDMPPPLLVVEVVSPHQENRDYRYKRSEYAARRIPEYWIVDPIQQRVTVLEWVEGLYEEVVYTGEKAIVSPVLGVLELTASRLLQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F351</accession>
    <name>A0A2G4F351_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2993 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56176">
        <property type="protein sequence ID" value="PHX56176"/>
        <property type="gene ID" value="CP500_006795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021373">
        <property type="entry name" value="DUF2993"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11209">
        <property type="entry name" value="LmeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="263" mass="28532" checksum="4F82986CAF83D32C" modified="2018-01-31" version="1">MTVDRNSLQFDNESGPADEQQIPNLGEQQEIPSRSKGSRIASAVLSPAVQLWLRSQVEQVSELNVKIEGSDRQIFSGTIPKVTAAAIGAVYRGLHLTSVAIEGAGIRVNLGQVIKGKPLRLLESFPIFGVLRLIQTDLNASLKAPMLADALSEFLLPLLPLTDQEGPLKLQNSQIAIDAGLLTLSAVILRADGTEIPFVLRTGLRMASGHELMFEEPELEISKQLNSNILNSFKIDFGPEVEIEELILNPGEIVCRGGIRVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F353</accession>
    <name>A0A2G4F353_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Urease accessory protein UreG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">ureG</name>
        <name evidence="6" type="ORF">CP500_006760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56204">
        <property type="protein sequence ID" value="PHX56204"/>
        <property type="gene ID" value="CP500_006760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01389">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004400">
        <property type="entry name" value="UreG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715">
        <property type="entry name" value="PTHR31715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00101">
        <property type="entry name" value="ureG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 4" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="5">
        <location>
            <begin position="6"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="198" mass="21397" checksum="782CA4BF898E4219" modified="2018-01-31" version="1">MSAFRVGIAGPVGSGKTALLDALCKSLRQQYKIAVVTNDIYTQEDAQFLVRSQALESDRILGVETGGCPHTAIREDASINLVAIEQLEYKFTDLDLIFVESGGDNLAATFSPELVDLTIYVIDVAAGDKIPRKGGPGITKSDLLVINKTDLAPYVGADLGVMERDTKKMRGEKPFVFTNLKTQTGLESVVDFVKLNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3J5</accession>
    <name>A0A2G4F3J5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SCP-like extracellular</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56291">
        <property type="protein sequence ID" value="PHX56291"/>
        <property type="gene ID" value="CP500_006045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="256" mass="25136" checksum="C1EC64ACE6BCA1E6" modified="2018-01-31" version="1" fragment="single">PTPTPTPTPTPTPSISVSIASPIANATGDGSPTQAPKNTASGGNYFLSDSGDSQIPVSAAGLPIFALSGKDSLTGGDGADTINGMQGADTINGGAGNDSLSGGKESDLIDGGVGNDFITGNNDNDRLIGGEGNDTLRGGKEDDILIGGNGDDLLAGDRDRDILTGGGGNDTFILGGGLSASATLTNADVITDFVAGDKIGLTDGIGFANLTFEAVSLRLDGGASQGSTAIKSGSNYLGIVQGVSQSQLTSIVFVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3K8</accession>
    <name>A0A2G4F3K8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56350">
        <property type="protein sequence ID" value="PHX56350"/>
        <property type="gene ID" value="CP500_005765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10456" checksum="797376A40DAB9561" modified="2018-01-31" version="1">MTDNLSQNLIVPFRYEDSAIAAVPTNILAEKRSSYQTHQELSDVQEPITSAPPEVRQIIERVLELEKDKLYMRAPRYISDDILKVIKEAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3X1</accession>
    <name>A0A2G4F3X1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">o-succinylbenzoate synthase</fullName>
            <shortName evidence="4">OSB synthase</shortName>
            <shortName evidence="4">OSBS</shortName>
            <ecNumber evidence="4">4.2.1.113</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-(2'-carboxyphenyl)-4-oxybutyric acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">o-succinylbenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">menC</name>
        <name evidence="6" type="ORF">CP500_005520</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10196"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18325"/>
            <dbReference type="ChEBI" id="CHEBI:58689"/>
            <dbReference type="EC" id="4.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; phylloquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 4/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.113" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56460">
        <property type="protein sequence ID" value="PHX56460"/>
        <property type="gene ID" value="CP500_005520"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00995"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043748">
        <property type="term" value="F:O-succinylbenzoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042372">
        <property type="term" value="P:phylloquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00470">
        <property type="entry name" value="MenC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010196">
        <property type="entry name" value="OSB_synthase_MenC1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="5">
        <location>
            <begin position="124"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="332" mass="37569" checksum="857A2A9EAB9D434C" modified="2018-01-31" version="1">MLYQFEFRTYQRKFKRALQTSHGIWQIRTGIILKLTDKNSQIGWGEIAPLSWFGSESFEQALDFCTSLSTHISEETIFSISDELPACQFGFESALSKEINAPPPAPPWQGGEKKMSQYSGLLPAGKISLSALQMLWKQGFRTFKWKIGVAVIEEELQVFQQLIEVMDDLCDREKAFLRLDANGGLNYSQAETWLQTCDDVARIPNFSVKIEFLEQPLSVTQFDKMLALTAVYKTPIALDESVANLDRIQECYNQGWRGIFVIKPAIAGSPSQLRKFCQTHNIDAVFSSVFETQIGKQAALNLATELFPNSRALGFGIDDWFDDNHSILDFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Z3</accession>
    <name>A0A2G4F3Z3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid oxidation protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56503">
        <property type="protein sequence ID" value="PHX56503"/>
        <property type="gene ID" value="CP500_004930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="16096" checksum="8784875B407FF777" modified="2018-01-31" version="1">MAAKDKFHDSVKRGLEKEKWKVTHDPLKLEYAKNERVEIDLGAERLLGAEKAGEKIAVEIKSFLNDSALADFHTALGQFLNYRLVLEELDPERTLYLAVPLASYESFFQRELPKASVKRHQVKIIVYNPVREEIVKWID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F499</accession>
    <name>A0A2G4F499_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56541">
        <property type="protein sequence ID" value="PHX56541"/>
        <property type="gene ID" value="CP500_004640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="98" mass="10597" checksum="5C421EC6677ACD51" modified="2018-01-31" version="1">MSQESLPDDNKSECPNDDSAALSEQDVVLLTVVSSPQGVRETILTLYQVGFAAVGDWSPVQRAANPKQVMSVLIRRRKRSSSRAALTADGTPPRKSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4B4</accession>
    <name>A0A2G4F4B4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_004215</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56623">
        <property type="protein sequence ID" value="PHX56623"/>
        <property type="gene ID" value="CP500_004215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005891">
        <property type="entry name" value="DevC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031773">
        <property type="entry name" value="DevC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01185">
        <property type="entry name" value="devC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="294"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="384" mass="42183" checksum="9EC26565BA58EC01" modified="2018-01-31" version="1">MFRKTPLAWLQVTREKTRLAVAIAGIAFADILIFVQLGFRDALFDSAVKPHQSLHTDLVLINPQFETFAAVKSFKRDRLYQTQGFEGVESVTSLHIDIGQWRNPTNRTTRAILIFGIDPGSITFNLPDVNQNLHQIQMFNHALFDQSSRPEYGDIAQIIQKESTLETELNKRNIKVSGVFTLGTSFTADGNVIVSDSTFMNLFSEQKPDEIDVGLINLKPGADIKKVQSMLKAALPDDVKVLTLAEFADIEKAYWANATPIGFIFGFGTVIGFIVGLIIVYQILYSDVSDHLAEYATLKAMGYSDGYLVGVLVQEALLLAVLGFMPGIVFANGMYSLAQSATLLPIVMTTDRAVFVLGLTIVMCTGSGAIALRKLQSADPADIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4D0</accession>
    <name>A0A2G4F4D0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1823 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56598">
        <property type="protein sequence ID" value="PHX56598"/>
        <property type="gene ID" value="CP500_004475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014952">
        <property type="entry name" value="DUF1823"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08853">
        <property type="entry name" value="DUF1823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="14068" checksum="886B83C8DBB995BC" modified="2018-01-31" version="1">MSELPPLNNETIWSILNEEIDDAAVNRLVWQYLGYRYDAETGIWNSANVAEEWRLEYPEPPDFIDSRPATVKLTRSIISENKQLLKEKLGFQGYKIGEFGPRQTRRATMANWLMGFISKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4J2</accession>
    <name>A0A2G4F4J2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metal-dependent carboxypeptidase</fullName>
            <ecNumber evidence="1">3.4.17.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_004015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of a C-terminal amino acid with broad specificity, except for -Pro.</text>
            <dbReference type="EC" id="3.4.17.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.19" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56669">
        <property type="protein sequence ID" value="PHX56669"/>
        <property type="gene ID" value="CP500_004015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001333">
        <property type="entry name" value="Peptidase_M32_Taq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217">
        <property type="entry name" value="PTHR34217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02074">
        <property type="entry name" value="Peptidase_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006615">
        <property type="entry name" value="Zn_crbxpep_Taq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00998">
        <property type="entry name" value="CRBOXYPTASET"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="507" mass="57838" checksum="2BDCACF52FBA44B1" modified="2018-01-31" version="1">MQTLDKTQTKFGQLTVRLSEIIDIESASSLLHWDQATYMPVRGASARSRQLATLKQISHEKFTDPKIGELLEDLRGYEQSLPYDSNTASLIRVARRDYDRAARVPAAFMAKLCRHQADSYEAWASAKATNNFAAVEPYLEKTLELSRQYANFFPEYEHIADPLIDRSDYGMKVSILRPLFAQLRQELVPIVEAIASQTPADDSCLHQNFAEAQQLEFTRTVVERMGYDFQRGRQDITLHPFMTNFSIDDVRITTRVYKDHLDQALFSSIHEAGHALYELGNSAEFEGTLLAGGISSGVHESQSRLWENLVGRSRGFWECFYPQLQGVFLRQLGHVTTDQFYKAINKVGRSLVRTDADEVTYNLHVAIRFDLELAMVEGKLSVHDLPEAWNDRYKTDLGIVPATDSEGAMQDVHWYVGTIGGMFQGYTLGNLMSAQFYETAVKINPEIPVEIERGNFTVLHDWLKQNIYQHGRKYTAVELVDRVTGSALSIEPFVRYIRHKYGEFYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4M9</accession>
    <name>A0A2G4F4M9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56671">
        <property type="protein sequence ID" value="PHX56671"/>
        <property type="gene ID" value="CP500_004035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="8"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="15112" checksum="8BD994789B16066A" modified="2018-01-31" version="1">MTLKISPALRREVFQRAEGRCEYCRLHQDFSIYTHEVDHVVARKHGGKTVLENLALSCLPCNRYKGSDLTSIDPQTGEITRLFDPRSDVWPEHFILENGRIIGLSAIGRTTIFLLKINIVTAVRNRQLFGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4R5</accession>
    <name>A0A2G4F4R5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phycobilisome protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56774">
        <property type="protein sequence ID" value="PHX56774"/>
        <property type="gene ID" value="CP500_003970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="2" id="KW-0157">Chromophore</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="17836" checksum="18197AA547C4028A" modified="2018-01-31" version="1">MLSQLARLSMEADGRYASAAELQFLKDYFQSLNHRMSAYKKIQASEKEILRQVETQMQSIDPNIFRRGSQDVTAKCRGDFAQVLRHSAAALLINDTERLRDRLLLWLQTILGAVQVKQTSPVTYDVMKKVIKQHLTAEEASLFLPILEIDRTILGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F555</accession>
    <name>A0A2G4F555_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56868">
        <property type="protein sequence ID" value="PHX56868"/>
        <property type="gene ID" value="CP500_003065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="214" mass="24696" checksum="757C7847D601EAA4" modified="2018-01-31" version="1">MVALQLRQITVPPGHRVLFHDVNWQEFEAILEELGEHRASRIAYSQGTLEIRMPLPEHEKAKIIIGYLVKILFEELEIDFEPFGSTTFKRKSMLQGIEPDECFYIQNYARMIGKKRIDLTVDPPPDLAIEVDLTSKTQLDAYEALGVPELWRYENNQLEINVLEDGKYVASEISPTFPNLPIVEAISQYCEQSQTAGTSQTLRLFRKWVREQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F586</accession>
    <name>A0A2G4F586_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56898">
        <property type="protein sequence ID" value="PHX56898"/>
        <property type="gene ID" value="CP500_002660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="578" mass="65926" checksum="784DA513DB5D2E2A" modified="2018-01-31" version="1">MTEDAGKKRYIRDFLHQVNSSAGFVDDIRIDRVVRLPGSEGEGSTAKSLSGRQISNLTELLKDDLRHTFDDGYFTFRFVAALVGSGKTSLLTYLHELAKTKPAYQKHSVVVEFQLSVFDEFIGKGFKKELYSHILAHTFYELSHNKELLDSVKNVARKVLRDYLSDTEVTQLNAAQDLMLFRTKFKKSIADNVDSLEEFFFSIVSKVSAVDPNFSFVYLIDELDALVTSPDQIKETRLLFKQLIRRAKEKFGSKIRLLIYLVGTSNNVESFIAEDSVMESLLGESVINLNKGYINEFELIRNKIDERIKGAYKGYKNFSQAWEEIKDITLNPVNTLREFCQHYAGAVLEIHEKYFQEAPEQEFEGNSRQLVESKCRQHWASYLKQKSYTLSAFLTTKKIKGHAFDCYVELLHNGTCVARAFGEAKNYELLSSHLEKFNQWLEAANFKPFTPDGTPGDLSFMIAPSCPPLLERKLELKNIQFIKSDKVIPPPIPTPTSTPIPKPTPTATPFPINLNKANKSEIKKAFNGTYIREKTIDEFIIDRNTEIYCDIDDMAFLGLTPAAKKILQTKFDKGEICF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5A4</accession>
    <name>A0A2G4F5A4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56952">
        <property type="protein sequence ID" value="PHX56952"/>
        <property type="gene ID" value="CP500_002950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="188" mass="21657" checksum="2E55D788CE13D8C8" modified="2018-01-31" version="1">METNMSNTHPSQIKSLMAKNGELQCAAAPIERINDHARSAIDHVMEKRQGFLQRFFPDAGTRAAIEGELALVKDEFEFRRRALQKVRETQIQSLTEHCNQYLVREKAAIRSDTAAFLMSKKLELENNLYSISEEFLTRMESQMAQAEAIQNPILKRVRQTQLEKSVEDFVDLQSRLVDQFQRIISEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5I9</accession>
    <name>A0A2G4F5I9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Rrf2 family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57030">
        <property type="protein sequence ID" value="PHX57030"/>
        <property type="gene ID" value="CP500_002255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="146" mass="16968" checksum="E8FB037843943640" modified="2018-01-31" version="1">MVELSCKSEYAILALLELADRYDEGEPMQIRQIAAEQNIPDRYLEQLLATMRRCGLIRSQRGAKGGYILAREPWKITLLEIINCLEGSDFDRSEKDSPAQTVESAVIWEVWQEARSIANSVLQKYTLQDMCEKRNGRRQLNFMYYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5M0</accession>
    <name>A0A2G4F5M0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57039">
        <property type="protein sequence ID" value="PHX57039"/>
        <property type="gene ID" value="CP500_002300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019494">
        <property type="entry name" value="FIST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013702">
        <property type="entry name" value="FIST_domain_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08495">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10442">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00897">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01204">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FIST" evidence="1">
        <location>
            <begin position="33"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="FIST_C" evidence="2">
        <location>
            <begin position="228"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="384" mass="41818" checksum="67717271011E095F" modified="2018-01-31" version="1">MLKTVVGHSNDPDSLYAIAEVLEQCHKSLSGLSPQAGILFAAIDFEHTLILNQINQTYPGIELIGGTTDGEMSSILGFEQDSLTLMLFCSDNITIRAGIGRDISQDLNCAIQTAIVQATTGHTEPIKLCITLPESLSTSAVLILDSLNQALGKKVPVIGGLTADRFQFKQTYQFYKTEVYSDAIPILLISGSILFSHSVASGWNPIGKRGKVTKSSQNVVYEIDSKPALEFYHHYLGERVPATEYPLAVFDINETHYYLRAPSAVYDSAVGSVTFFGDVPEGAIVQIAETTHDSILSASRTSMMQALQNYPGKEPAAALYFSCCARRQILGTRTKEEYALTQTCLTQSLPSCGFYTNGEISPLEQQGISCFHNETFITLLLGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5N9</accession>
    <name>A0A2G4F5N9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF928 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57059">
        <property type="protein sequence ID" value="PHX57059"/>
        <property type="gene ID" value="CP500_001905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010328">
        <property type="entry name" value="DUF928"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06051">
        <property type="entry name" value="DUF928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013653288" evidence="1">
        <location>
            <begin position="24"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="14808" checksum="AA219186621F873B" modified="2018-01-31" version="1">MAWIKCHLNTAALCLILSLEAVATASFSMPAEALNNPANGIRSPDIPHLTVHWATVSRWINRTASAPTLKTKLDRSSKRDRLTILTQQAIWYKYLTTLAQLRVSSPSDRSLSRCVGANRHSPLQGFPFQHQGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5P0</accession>
    <name>A0A2G4F5P0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4276 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57021">
        <property type="protein sequence ID" value="PHX57021"/>
        <property type="gene ID" value="CP500_002200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025455">
        <property type="entry name" value="DUF4276"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14103">
        <property type="entry name" value="DUF4276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="199" mass="22457" checksum="D54BEBDA3824BCDE" modified="2018-01-31" version="1">MKIAIIVEGKTETAFMPILRSFLKSRLQQMPKLDTKPQHGRIPKEDKLKRVVENLLDKDGYDAVIAITDVYTGTKDFRDAADAKAKMAAWVGKNPNFYPHAASYDFEAWLLPFWSKIQQISGGNRAVPSGDPELVNHNNPPSDRIKEIFEQGKRRSYDKARDAKKILEGQNLVDAAKVCPELKAFLNTILFICEGELIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F634</accession>
    <name>A0A2G4F634_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57220">
        <property type="protein sequence ID" value="PHX57220"/>
        <property type="gene ID" value="CP500_001355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="219" mass="24532" checksum="098D10E6FBA7F1EE" modified="2018-01-31" version="1">MSEVSKKDSVCKQDTDKVLLVEGDNDCHVVMALCKAHNVPETFGIYQCGSDVGVLKRLNALIIRPNPPQVIGVMLDADNPSVEGRWQSIRGKLQHYSYRFPSKPDADGTVVETSSDEPKLGFWLMPNNQTSGMLEDFCAELAEPESLAFARECVEQAEDNQVTTFKEVHRSKAVIHTYLAWHDEPGYPLGKAITSQALRPHTDVAVKFTNWLIRLFVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F689</accession>
    <name>A0A2G4F689_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF928 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57303">
        <property type="protein sequence ID" value="PHX57303"/>
        <property type="gene ID" value="CP500_000520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010328">
        <property type="entry name" value="DUF928"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06051">
        <property type="entry name" value="DUF928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="260" mass="28832" checksum="0601295D4F8CC7A7" modified="2018-01-31" version="1">MTSITKRIQLGLSLVILSLTSIYPELVAQSATGELFNNTSIGQNRTRKRVHFVTPTIKPSGSRRHGSTHSDYRTGGASRGDCPMVKKPLTALIPDTNIGLTISEHPTLWFYIPYTAVNNRSAELVLLDEKNKLVYSTALPLAKTSGITKVTIAKTLEIGKTYKWVFSVICNPANRTGDKFVKGEVRRELLSSAVQNQLKEVTEEHDRAIIYAENGLWFDALTSLAELRLKAPQDQNFIEEWADLLGEIGLADIASEDFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6E0</accession>
    <name>A0A2G4F6E0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57320">
        <property type="protein sequence ID" value="PHX57320"/>
        <property type="gene ID" value="CP500_000630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="22278" checksum="889D5940473D60F8" modified="2018-01-31" version="1">MIAAKENFPQITPEEYFAWEEKQLEKHEYIDGQVYAMSGGSVNHGRLAIRLTAMFDSHLENSGCITGNSDIKINIVETRNYTYPDASVTCDDRDKTTTQYITYPCLIVEVLSPSTEAYDRGGKFRMYRRNPVLQDYLLVSSTSIEMDLYHKKDTGEWLIINYKEGDTIELKSINLCFAIEQVYRNLDLTPETTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6H6</accession>
    <name>A0A2G4F6H6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57394">
        <property type="protein sequence ID" value="PHX57394"/>
        <property type="gene ID" value="CP500_000180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026337">
        <property type="entry name" value="Mod_HExxH"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04267">
        <property type="entry name" value="mod_HExxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="285" mass="32596" checksum="261555163A18D04B" modified="2018-01-31" version="1">MFFLNLPHTVTNVLKFVHANSGIKPCQKNLKELFTIQLSQIQKSNLTLADLPLISFGTRRISRTQEAFMNSGFGFIEEFTPDEEAPIKDNFKQSLLLIQKIDSRLFEMLRILISDIVFIKSPLKENKGGGSGTSSHVLGVIWITPGEHWAVETYVESILHEFMHVNLFLGEAVYGLYKNKENLDEQEALVMSAIKRIPRPLDRAFHAACVATVLVYFYHLLDQKNSVKTFLEPLIESVSGLVERQDYFSAYGQAIIQQMSCFTTDPDFDYLRKVINDRQLAQFHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Q1</accession>
    <name>A0A2G4F6Q1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1499 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57167">
        <property type="protein sequence ID" value="PHX57167"/>
        <property type="gene ID" value="CP500_001530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010865">
        <property type="entry name" value="DUF1499"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07386">
        <property type="entry name" value="DUF1499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026426">
        <property type="entry name" value="DUF1499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="14167" checksum="C88868D11DDBD7AB" modified="2018-01-31" version="1">MFAGKRPTNLGIQSGQLAECPSSPNCVSSFSQDAEHKIEPLTYSSTPTVAMASLKGAIASLDKTKIIDQTDNYLYVEFTSSLMGFVDDVEFLVDEGAKVIHVRSASRLGQSDLGVNRKRIETIRAQLNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6S6</accession>
    <name>A0A2G4F6S6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57411">
        <property type="protein sequence ID" value="PHX57411"/>
        <property type="gene ID" value="CP500_000275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="242" mass="27833" checksum="665181A79B6598E6" modified="2018-01-31" version="1">MMKIAVILPVYNEANCIEKTFDEILEFSQKNHAYNFIIVNDGSTDDTLKIIENKLNTSPTYNIKLISYRDRQGKGYAVKKGSESVDADCICFMDGDLAYSLEHIEPLVEKLEKFDVVIGCRNLDRHNFRNLTLIRKISGKIFNFISRKILNLPYRDMQAGLKGFKNKAAQEIFKQQTITGFSFDAELLFLAQKKGYTIGEIPARVSEQHLYKISKVNIVKDSLEMFSCLLKIRYNNRAGNYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F752</accession>
    <name>A0A2G4F752_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000005</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57447">
        <property type="protein sequence ID" value="PHX57447"/>
        <property type="gene ID" value="CP500_000005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="457" mass="53331" checksum="3628909A861202A6" modified="2018-01-31" version="1">MALVALGNLSLVLFDISYVPWRDFYERELPLITQAYDPFKGIKPHRDTQKYLESLDELKKQLVQTGLASPKITAQLQELDNLSTKMIDEDPFRAASKSGTLEKIKDRLRERIPNPQYSAKQSFKTFWSQDYLSRQGWQQEINWFDSKIKPLIATNYYREIGDNGELKDDFWMIDLPFILIFAIEFLARTYTISHRHRSVSWRAAMLWRWYDIFMLLPFWRLLRVLSVTIRIHQAKMPDLQPIRIQISRGFVANFAQELTEVVVIQLINQMQQSISSGELAKQLFQSEKQRYLDINNINEIEAIATHLVQITVHKVLPQLQPDLEALLRYNIEMFLKQSPLYQGWKQVPGLGNLPAQLAEQLVAELSKLATLGPQDAYEAFKIASEDPIGTKLSSQLVQHFGQALGAELQQQQTWKEIQLLLCDFLEEFKINYIQRLSEEDFEKILEQAKELQRIAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUM6</accession>
    <name>A0A2G4EUM6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000229">
        <property type="protein sequence ID" value="PHX53252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53252">
        <property type="protein sequence ID" value="PHX53252"/>
        <property type="gene ID" value="CP500_022485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="11"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="325" mass="37621" checksum="C5FD59EBC860529E" modified="2018-01-31" version="1">MTSSSSKIPVSVLIPAKDEELNLPACLASIARADEVFLVDSQSSDRTVEIALNSSAKVVQFYFDNRWPKKKNWSLDNLPFRNEWVLIVDCDERIPPELWDEIAKVIQNPNFEGYYLNRKVFFLGQWLRYGGRYPDWNLRLFKHQKGRYENLGTESVPNTGDNEVHEHVILAGAVGYLKNDMIHEDYRDLFHWIERHNRYSNWEARVYYNIIEGRDDSGTIGAHLFGDAVQRKRFLKKVWVRLPFKPMLRFILFYFIQLGFLDGKAGYIYARLLSQYEYQINAKLYELRSCGGQLNVAESEPTLSPPESDSAVKTAATKTKSASAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUS9</accession>
    <name>A0A2G4EUS9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc metalloprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_022290</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000222">
        <property type="protein sequence ID" value="PHX53285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53285">
        <property type="protein sequence ID" value="PHX53285"/>
        <property type="gene ID" value="CP500_022290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016483">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006404">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="308"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX53285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="396" mass="43036" checksum="8BF35663CA717A02" modified="2018-01-31" version="1">MQTGWRVGSLFGIPLFLDYSWFIILALGTRAYASSYSAWGPALSWSAGLAVALMLFGSVLLHELGHSLAAMSQGIKVNSITLFLFGGVASIDSESKTPGQAFQVAIAGPLVSFGLFLILGLGSEVLPPTNLLRIVTERVAEINLVLGLFNLIPGLPLDGGQVLKAAIWKITGSRFTGVRWAARTGQFLGWLAIALGLTSCLLARELGGLWIALIGGFAIRNATAYSRFVSLQEALIKTKAVDAMTREFRVVDANSTLREFADRYLLEVNPLPFYVAADNGRDLGLVSIDDIRFTERSQWQIQTLHNILKPLQKTPTVSEKASLAEVINTMEYCQLSRIIVLSLIGSVVGTIDRGDVMKVLAKYLKPTFSEAEIKRCKAENIYPQGLQLSAIAKTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV63</accession>
    <name>A0A2G4EV63_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000200">
        <property type="protein sequence ID" value="PHX53421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53421">
        <property type="protein sequence ID" value="PHX53421"/>
        <property type="gene ID" value="CP500_021580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="6"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="11072" checksum="AF8D43496DBD08D4" modified="2018-01-31" version="1">MSQPTLRVVAHLIAFPEKVEELKSLLLSIVDPTCKEAGCIKYELLQNQADPTDFTFVEEWESADLLELHLASTHIQAAVLKLEGLAVSPPDIRRYELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV85</accession>
    <name>A0A2G4EV85_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_021940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BioY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53350">
        <property type="protein sequence ID" value="PHX53350"/>
        <property type="gene ID" value="CP500_021940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015225">
        <property type="term" value="F:biotin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003784">
        <property type="entry name" value="BioY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34295">
        <property type="entry name" value="PTHR34295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02632">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016661">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR016661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="192" mass="20884" checksum="CDE76B6930C05648" modified="2018-01-31" version="1">MPAPIELIWAFIGLLLTIGGAFFPAFVTTPIWFGDERGFQAYSLGVNYQIGAVLLVGCMGGKNAAALSQIAYLVLGLTLWPVFAQGGGIGYLREPSFGYLLGFVPGAWVCGWLAFKVASRLESLAFSCLCGLFTVHAIGLIYLIFTHSIPPIRTTPLFDEILKYSVYPMPGQLAVVCAIALLSFVLRRLMFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVU1</accession>
    <name>A0A2G4EVU1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">S-adenosylmethionine decarboxylase proenzyme</fullName>
            <shortName evidence="10">AdoMetDC</shortName>
            <shortName evidence="10">SAMDC</shortName>
            <ecNumber evidence="10">4.1.1.50</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="10">S-adenosylmethionine decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="10">S-adenosylmethionine decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="11" type="primary">speD</name>
        <name evidence="10" type="synonym">speH</name>
        <name evidence="11" type="ORF">CP500_020240</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>H(+) + S-adenosyl-L-methionine = CO2 + S-adenosyl 3-(methylsulfanyl)propylamine</text>
            <dbReference type="Rhea" id="RHEA:15981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="4.1.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="10">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.50" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000164">
        <property type="protein sequence ID" value="PHX53672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53672">
        <property type="protein sequence ID" value="PHX53672"/>
        <property type="gene ID" value="CP500_020240"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00331">
        <property type="reaction ID" value="UER00451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006557">
        <property type="term" value="P:S-adenosylmethioninamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00464">
        <property type="entry name" value="AdoMetDC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042286">
        <property type="entry name" value="AdoMetDC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042284">
        <property type="entry name" value="AdoMetDC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017716">
        <property type="entry name" value="S-AdoMet_deCOase_pro-enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33866">
        <property type="entry name" value="PTHR33866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="SSF56276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03330">
        <property type="entry name" value="SAM_DCase_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="2 10" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 10" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8 10" id="KW-0704">Schiff base</keyword>
    <keyword evidence="4 10" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023541556" description="S-adenosylmethionine decarboxylase beta chain" evidence="10">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023541557" description="S-adenosylmethionine decarboxylase alpha chain" evidence="10">
        <location>
            <begin position="63"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="10">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for processing activity" evidence="10">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for catalytic activity" evidence="10">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autolysis" evidence="10">
        <location>
            <begin position="62"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="10">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="15107" checksum="CCF7F03E72F5A52E" modified="2018-01-31" version="1">MKQLGTHLVADAWQSPGDLLNDPERIRRAILDAIEAGGATLIDLCVHQFSPHGVTATATLAESHIAIHTWPEHGYFAADLFFCGAGDPHKAMKVLQTALEAKQVKLTEFTRGFEPGMGILGSASEEQYAPRLIETTAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW35</accession>
    <name>A0A2G4EW35_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mo-dependent nitrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000163">
        <property type="protein sequence ID" value="PHX53676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53676">
        <property type="protein sequence ID" value="PHX53676"/>
        <property type="gene ID" value="CP500_020175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009717">
        <property type="entry name" value="Mo-dep_Nase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06967">
        <property type="entry name" value="Mo-nitro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mo-nitro_C" evidence="1">
        <location>
            <begin position="211"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="293" mass="32758" checksum="CAB49AFF7319B881" modified="2018-01-31" version="1">MLLTRPLQAFRAIFRYTPSTNGTIEQKSSKSYLGGNITPTPNQQIEWFIEVERLMNNVKSSCTNEEITAWLRGLLTIAWSDGNFDENEQKLIAALSQDELNPVSVETGFESITPEELAAVLGKGTAIGENFLRTAVMVALADGIYSVCEDELLHKFCTALGQNVETIEALRHTIEETKCQPQPPTISVAAVEGNPASSLSARRPQPPQKNVLQPVKDWLDGWEIHDPRVAHFVCKMIPSQCPFERDVVLFGRKIVHIPAMCQINPLYEQLVGMRFRALCYLADDCKEDISSYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW57</accession>
    <name>A0A2G4EW57_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53759">
        <property type="protein sequence ID" value="PHX53759"/>
        <property type="gene ID" value="CP500_019800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="62"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="312" mass="35167" checksum="6DB5EBE9C4C69345" modified="2018-01-31" version="1">MSIKRRYFLILGSLSSLGFAAIIWKMFQLRTSWGTDAYAAMPPGVEGERAIAPLPTTPPILRFISIADTGTGAQGQYAVAEAMAQYHGQNPFDLAILAGDNIYNNGEFEKINAVFERPYQPLLQQGVKFYACLGNHDIRTANGDLQVKYAAFNMQGRYYTFRRESVQFFALDTNDNADWKNQLVWLEKELSQSTAPWKVVFGHHQIYSSGIYGLNQPFIKTLTPMFQKYGVQLYINGHEHSYERTRSINGTTYLICGAGAGTRPVGRSEWTEYSASRLSFATFDVYEDRMFVSGIGTDKRVFDRGVIEVRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW84</accession>
    <name>A0A2G4EW84_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53700">
        <property type="protein sequence ID" value="PHX53700"/>
        <property type="gene ID" value="CP500_020065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="8915" checksum="3A96D6BE3F40E7CA" modified="2018-01-31" version="1">MNPTSTVTISNTSYQALAELSASSGKPIQTVLEQAIEQYRRQQFLAAANQAYITLRDRPEDWQEELEERAAWAITLQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWA3</accession>
    <name>A0A2G4EWA3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">hemL</name>
        <name evidence="9" type="ORF">CP500_019475</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53813">
        <property type="protein sequence ID" value="PHX53813"/>
        <property type="gene ID" value="CP500_019475"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="432" mass="45759" checksum="95337E35444950F1" modified="2018-01-31" version="1">MVSTTLKTTKSEEIFAAAQKLMPGGVSSPVRAFKSVGGQPIVFDRVKGAYIWDVDENQYIDYVGTWGPAICGHAHPEVIKALHESLEKGTSFGAPSLLENVLAEMVIDAVPSIEMVRFVNSGTEACMAVLRLMRAFTGRDKLIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPKSVTANTLNAPYNDLEAVKALFAENPGEIAGVILEPVVGNAGFIVPDAGFLEGLREITKDNGALLVFDEVMTGFRIAYGGAQEKFGVTPDLTTLGKVIGGGLPVGAYGGRRDIMGMVAPAGPMYQAGTLSGNPLAMTAGIKTLELLQKPGTYEQLDKITKKLSNGLLQIAKETGHAVCGGQISGMFGLFFAAGPVHNYDDAKKSDVAKFGRFHRGMLEHGIYLAPSQFEAGFTSLAHTEEDVDRTLAAAREVMASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWD6</accession>
    <name>A0A2G4EWD6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CP500_019700</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53776">
        <property type="protein sequence ID" value="PHX53776"/>
        <property type="gene ID" value="CP500_019700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="16">
        <location>
            <begin position="383"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="447"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="15">
        <location>
            <begin position="524"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="828"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX53776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="931" mass="103827" checksum="D65B4F5DD33F410C" modified="2018-01-31" version="1">MITPSSVKVVDQTNSASKLAIKTAHAVNLRTVLIVPFVLQIFAAVGIVGYLSFRNGQQAVNEVASQLRQEISDRISERVQAYMTFPQQLNQLKANAFELGDLNLQDTPRVHRHFWKQLQTFDTVSVTYIATPGGDFIAARRTNDGSFLLQERSELTEGRMNYYAVNNNGEPTNLVKIRPKYDPRVRPWYTAATEAKTATWSKIYADFTSKGLGITAAQPLYDTSGQLQAVFGTDLLFSQVNEFLGKLKIGKSGQTFIIERSGALITTSTTDPVYLIKGEETERIQAIDSQNPVISLTTKYLQKSFGNLSNIQQTQGLNFKIEGQLQFMQVTPLKDDKGLDWLIVVIIPEADFLEQINANTRTTIWLCIGALTGAIVVGVFTARWVTKPILYLNETAKNITKGQWGKIVEINRNDEVGELANSFKSMAEQLQVSFAEMQALNVELSESKSRLDQILEAVPVGIFVAESNGKPYYINSRAKSLLGQGIVDNISPDEIREKYQVYLAGSNEIYPQDKDPILCAFKGSSVNVDDLEIHKGDRVIPIEVWGTPIYDDQGNVSYAIAAFADITQRKEAENLAAEYNHTLETQVTEITQELSKTLDYLQATQNELIQSEKMAALGQLVAGVAHELNTPLGAIRSTAGNMTKFWGQTLSKYGRMAIRPYPSLFQSLSPAEAENFFLLLNKSLQKDMSLTAKEERKLKRSLISQLEDQDIDNADDIADTLVDMGIYEADDFWVLLQNGDRDRILEMAYKLTEIQRGIQTINTATDHASKVVFALKNYARYDSSEVMIQSDIVEGIETVLTLYQNNIKHGVEVLRNYQAIQPILCYVDQLNQVWTNLIHNALQAMDNTGTLIIDIIQEDNYVKVAVTDSGKGIPAEVMPRIFEPFFTTKPPGEGSGLGLDIVKKIIEKHHGKIEVASVPGKTTFTVFLSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWH9</accession>
    <name>A0A2G4EWH9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division topological specificity factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">minE</name>
        <name evidence="4" type="ORF">CP500_018920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the MinE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000141">
        <property type="protein sequence ID" value="PHX53912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53912">
        <property type="protein sequence ID" value="PHX53912"/>
        <property type="gene ID" value="CP500_018920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1070.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00262">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005527">
        <property type="entry name" value="MinE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036707">
        <property type="entry name" value="MinE_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03776">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55229">
        <property type="entry name" value="SSF55229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01215">
        <property type="entry name" value="minE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="12492" checksum="99F7E7A5E6370098" modified="2018-01-31" version="1">MIYTLLERLFPRTSDNSRDEVKRRLKLVLAHDRSELSPEMVEAMRREILEVVSRYVEIDTMESEFSLASDQRATSLIANLPIRRVRVERSPEYVPDDLVEALPDTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWR5</accession>
    <name>A0A2G4EWR5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53974">
        <property type="protein sequence ID" value="PHX53974"/>
        <property type="gene ID" value="CP500_018530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7686" checksum="EFC1453BBE7A5E2E" modified="2018-01-31" version="1">MTKPDRTTVDIKGLRERITAVSALPELADRALSSVLRILVTKGLESYEEKLAQSTQQQISPRTEKSTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWT7</accession>
    <name>A0A2G4EWT7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="9">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">thrS</name>
        <name evidence="12" type="ORF">CP500_018840</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000139">
        <property type="protein sequence ID" value="PHX53938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53938">
        <property type="protein sequence ID" value="PHX53938"/>
        <property type="gene ID" value="CP500_018840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="11">
        <location>
            <begin position="238"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="614" mass="69901" checksum="8FA2A3A860BC8218" modified="2018-01-31" version="1">MLNQPMSSSESISAPEQPAKIDLPRTSESEQLKKIRHTTSHVMAMAVQKLFPKAQVTIGPWIENGFYYDFDTPEPFTEQDLKAIKKEMIKIINRKLPVIREEVSREEAQQRIQAINEPYKLEILAGLIEPITLYHLGDEWWDLCAGPHLDNTSELNPKAIELESLAGAYWRGDETKAQLQRIYGTAWETPEQLAAYKHRKEEALRRDHRKLGKELGLFIFADAVGPGLPLWTPKGTVLRSILEDFLKQEQIKRGYLQVVTPHIARVDLFKISGHWQKYKEDMFPLMAEDAEAAANEQGFVMKPMNCPFHIQIYKSELRSYRELPMRLAEFGTVYRYEQSGELGGLTRVRGFTVDDSHLFVTPEQLDAEFLSVVDLILSVFKSLQLKNFKARLSFRDPDNLDKYIGSDEAWEKAQGAIRRAVETLGMNYFEGIGEAAFYGPKLDFIFQDVLDREWQLGTVQVDYNLPERFDLEYVAEDGTRKRPVMIHRAPFGSLERLIGILIEQYAGDFPLWLAPIQVRLLPVSNEFLPFAKEVAAKMKALGMRAEADESSERLGKLIRNAEKDKIPVMGVVGAKEVESNSLNIRTRASGELGAISVDEVIGRLQVAISSYGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWU3</accession>
    <name>A0A2G4EWU3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2973 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000139">
        <property type="protein sequence ID" value="PHX53936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53936">
        <property type="protein sequence ID" value="PHX53936"/>
        <property type="gene ID" value="CP500_018830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021355">
        <property type="entry name" value="Phage_Syn9_Gp224"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11189">
        <property type="entry name" value="DUF2973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="11444" checksum="54D27A5F9D5C43EC" modified="2018-01-31" version="1">MLHLLYILAFTVLAFLAVGNLIRSLVTVGMESQRPQQFRQNNPYASYPRSLAVPHPELLDEYGNIVNEPLLVMRSLTVQDAREKLDALYKSSPGGSDEGGELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWZ3</accession>
    <name>A0A2G4EWZ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation initiation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_018220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000129">
        <property type="protein sequence ID" value="PHX54054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54054">
        <property type="protein sequence ID" value="PHX54054"/>
        <property type="gene ID" value="CP500_018220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11567">
        <property type="entry name" value="YciH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005872">
        <property type="entry name" value="SUI1_arc_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037511">
        <property type="entry name" value="Transl_init_SUI1_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="SSF55159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="SUI1" evidence="4">
        <location>
            <begin position="54"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13168" checksum="99F4F84FCCD5DBF3" modified="2018-01-31" version="1">MSTSKPKNSNSNNQSEKRIVYSEFGNVDNSAALQRGIQEIPPNQQNLKIEASRKGRGGKTVTVISGFQGKPETLANLAKQLKAQCGTGGTVKDNEIEIQGEHKQKLLEILTKLGYKAKISGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWZ8</accession>
    <name>A0A2G4EWZ8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="11">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">trpB</name>
        <name evidence="13" type="ORF">CP500_018205</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the TrpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000129">
        <property type="protein sequence ID" value="PHX54051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54051">
        <property type="protein sequence ID" value="PHX54051"/>
        <property type="gene ID" value="CP500_018205"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="68"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX54051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="413" mass="44834" checksum="BDCCBC175C9CF5A5" modified="2018-01-31" version="1">MTVTPLRLTTETTTAQRPDSLGRFGKFGGKYVPETLMPALFELEAAFHKYRSEPEFQQQLQGLLKDYVGRPSPLYFAERLTEHYAKPDGSGAQIYLKREDLNHTGAHKINNALAQALLAKRMGKKRVIAETGAGQHGVATATVCARFGIECVVYMGVHDMERQALNVFRMRLMGAEVRGVSAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAIIGQETRAQCQEKWAGLPDILLACVGGGSNAMGLFHEFVGEETVRLIGVEAAGEGVETDKHAATLTKGTVGVLHGAMSYLLQDNEGQVIEPHSISAGLDYPGVGPEHSYLKDVGRAEYYSVTDAQALDAFQRLSQLEGIIPALETAHAIAFLDTLCPQLTGNPRIVLNCSGRGDKDVQTVAKVLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX38</accession>
    <name>A0A2G4EX38_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YjgP/YjgQ family permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_018025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54093">
        <property type="protein sequence ID" value="PHX54093"/>
        <property type="gene ID" value="CP500_018025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="388" mass="43108" checksum="69DD5A16D839ED48" modified="2018-01-31" version="1">MKIAMSKSFNPLNWLPRISVMDWYIVKELMGPFLFGVGLFTSVAITVGALFELVRRVAESGLPYGAAIEIFMLQIPYFVVLAFPMSMLLATLMAYSRMSSDSELVALRSCGVSVYRLVIPAVILGLVVTALTFPLQELVVPAANYRATLTLDKALKRETPLFQKGNIIYTEFRTNDKSANETLARFFYAEEFDGKRMKGLTIIDRSTPGLNQIVSSESATWNPSQNTWDFFNGTAYIVAPDGSYRNIVRFEHQQLKLPRTPLDLAAKARDFKEMNIAQALERLELIKSSGDEQQIRKLMVRIQEKYAFPFVSMVFAIVGAALGTQPRRSGKGTSFGISVVVIFTYYVFSFVTSSMGVKAVLSPILSAWLPIAFGFGIGGVLLVRAASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX46</accession>
    <name>A0A2G4EX46_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54020">
        <property type="protein sequence ID" value="PHX54020"/>
        <property type="gene ID" value="CP500_018470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="212" mass="23218" checksum="43A68406C41181C7" modified="2018-01-31" version="1" fragment="single">GREGERGGEDFSVFPIEVIPNGVDLIEFPDRAIDPGGHTLIFAGAMNNLPNIDAARFLSLEILPIVQQRYPDTTLTLVGHSPVPSVLALAKQPGIQILGRVQKVAKYLHQATVCVVPMRIGFGIKNKTLEAMAAGTPVVASDRGLEGLAIGGGPQPIRALRANRIQEYVEAISSLFENPHLRHELSRNARSHIENQYTWNTIGQRYDRLLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX77</accession>
    <name>A0A2G4EX77_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beta-galactosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_017750</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000121">
        <property type="protein sequence ID" value="PHX54144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54144">
        <property type="protein sequence ID" value="PHX54144"/>
        <property type="gene ID" value="CP500_017750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Glyco_hydro_2_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_hydro_2_N" evidence="7">
        <location>
            <begin position="61"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_2" evidence="5">
        <location>
            <begin position="232"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_2_C" evidence="6">
        <location>
            <begin position="430"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1267" mass="141623" checksum="165C54480EC3A087" modified="2018-01-31" version="1">MNNQLAKIIGLFFAAAITFGFIGYALQNPNSVSNSVMSIGFSNATIATASAIDNKRDQIYLNGTWQFVPAIGNPQNPPPSPSWGSIQVPGDWQKEKSESVPGIISRGTGKDWENFNSKQLSKAWYQRNIEIPSDWTNRRIFIDLARVSTDAIIFVNDINSGQIEWPYGTIEITKLAQPGQNTISILVAAVSDEQDKTVIMGPTEIYTTKSNLQSRGIIGEVRIFSLPPGPLISDVFVQTSTRNQQIKLDVELKDVKQNGQIQLVAQMLDEKGKIEQKFTGTAQVQAKPIQTVKVQWDWKNPRIWDAGKPNLYTLKLEVKGSGVNTHYDQPFGFREFWIEGRKFFLNGTEFRLRPILHPDSWESGTVEGSDKLIEGYNKAGFNIVETWPWNHDERGKWHFRELFSERADLKGFPVMAPALDISLLASNGKWNNRQIRDRWKSRMTTEMRRYRNHPSILMWSTSPNCFGNTDDQNPRRIGKKVVAGTLDANRLRDITTLANESFASMKSVDPTRPVMVHQGANFGDVYALNSYLNVIPLQEREEWISEWSKTGEMPYMVVEFGTPLHATMMRNRAGFGNVIVSEPLMTEFTAIYLGKQAYELETTAYKNKIREQFVKGQKYKSWHLNKELDFAPAFQKLQQLFSTNTWRSWRTFGMSGGMIPWNEGHGWQVSDAGRTKVDIGEFQPGRRGVYLKQVSKSLLYHLQPEAYTIHPSGEAIMKNNSSTLAWIAGSSPAFTAKDHTFWAGGKLAKQVVLINDTRAKQNFAFTWRVLLGGQEVGKGKKQGTIDTAGTLFFPIDVKLPNDILGKTDGEISLTAKVGDRTHADIFTFRAFATPTKIKDTIAIFDPVGKTSAMLKQLGDELVPWNGSQVSSLLIIGREAFSSGQNLPGNLETFVRNGGKAIVFPQRREWLTNKGLRVAEHISRRVYPIDSNHPVVSGLDEVDLRDWTGESTLLESYPDTIQKPSRLSPANTPWYGWHWGNRGGVSSASIEKPHRSSWRPILESEFDLAYSPLMELDYGKGRLILNELDLEDHFAADPGAAQLAQTLVSYGMDSVVSGKQDRVVLIGGDGDAKKLDSLGVIYQRANGLSKDVGLAIVGAQANVKDSDLRAYLNGGGKAFFLPRQVPVAGLGVDLQPAKDFGGSLTVPIWDEVRGVSGSDLRSRSFYDTWLIKSGGEIGADGLLSRVAVGKGVAIFSQLDPDSLNADAKTYLRFTRWRQTRANAQILANLGASFKADGVVFNGSSQEFYHSDYRTDFENGDDPYRYYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXC1</accession>
    <name>A0A2G4EXC1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000117">
        <property type="protein sequence ID" value="PHX54183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54183">
        <property type="protein sequence ID" value="PHX54183"/>
        <property type="gene ID" value="CP500_017515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029494">
        <property type="entry name" value="DarT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14487">
        <property type="entry name" value="DarT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DarT" evidence="1">
        <location>
            <begin position="6"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="209" mass="24779" checksum="2DE584DD27E89C73" modified="2018-01-31" version="1">MPIPIYHITHIDNLESILSEDGLLAYNVMLETQTNYTNIAYENIQDRRATTYVPWDGGGVLHDYVPFYFAPRSPMLYTISRGNVENYTQGQAAVIHLVSSVENIKDKDLCWVFTDGHAVMKFTDFFDDLNYLDDAIDWDVMESRYWNDTNQDNDRKRRRQAEFLVRYFFPWQLITEIGVMDYTIKTQVENILQNFTHKPSVIVRNNWYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXC6</accession>
    <name>A0A2G4EXC6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017435</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245735">
        <property type="entry name" value="M.Tbo703ORF17435P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54194">
        <property type="protein sequence ID" value="PHX54194"/>
        <property type="gene ID" value="CP500_017435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="4">
        <location>
            <begin position="27"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="312" mass="35898" checksum="F15F87AF7AF821A3" modified="2018-01-31" version="1">MKKTPSNEVLVGDCREVMKTLPENYISACITDPPYNYEFIGHKWDDSEIQRRIERVNDKGSKTLVKNIPYGSGLAGGVRNEKWYQRNRNNTLEYENWCFDWGEQLFRICKPGATVLVFNSTRTVAHVQVALENAGFYPRDMLVYKRSSGIPKGVNIKQQFEKKGYENPEQWDGWHSCLRNEWEAICVLQKPLVNNYLETLQEYGTGLFYTKDRFGGFQSNILEGIQREKTEDFNVHCTVKPIALMRQLVEIFVPRLENSILIDPFAGSGTTLLAAQEFGIKYVGIEIVPDYIEIIKKRLDSFSGVQGILPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXY0</accession>
    <name>A0A2G4EXY0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54395">
        <property type="protein sequence ID" value="PHX54395"/>
        <property type="gene ID" value="CP500_016250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="249"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="36046" checksum="512421E30AB230DA" modified="2018-01-31" version="1">MRFINPKIDFAFKKIFGSTQSTEILISFLNAILYEGESVIESLEILDPYLGPQIAGAKNSYLDVKALLNDGTFVIIEMQVLKVQAFGKRVLYNAAKTYALQLTRGELYKELRPVIALTITDFEMFSGHEDVTSHFVFKEKTRLSDYIQNDIELVFVELPKFKKELEQLESLTDKWIYFIKTTGTLDEVPQTMATVPQIQRAFEIANQLSLTQEEFNILQQQEFFAQDQEGSVALGREEGRQEGRQEGRQEGRQEGQVKLIMRLLSRRLGQINPDFESRIRQLPIDKLENLAEAMLDFSNAEDLTAWLEANSPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXZ1</accession>
    <name>A0A2G4EXZ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54320">
        <property type="protein sequence ID" value="PHX54320"/>
        <property type="gene ID" value="CP500_016735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="32314" checksum="ADB9A5431D2E2EA9" modified="2018-01-31" version="1">MSQPKSIEISNVTRYQNAALNYYLGLTDSPYLHYGYWETLPVPTDELTLARLRIAQQAYTVKLLDAIPKGTHSILDVGCGIGGNAAYLLDRGFAVEGLAPDPFQQQRFLKCTADRAIFHLTTFENFQAIKFYDLILFSESSQYMSAVDIANGAAKILNPGGYVLLADMLRSDANYQEGMFSNCHVVSELHAALKQAGFTLVKTEDISAHIVPTIDLYVDTFRRYGLNTMIYVADLIAIAVPPIHKLLRWIFRRWFKKLVVEGLEASQLFEQHLCYEIQLWELTVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY67</accession>
    <name>A0A2G4EY67_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RRXRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54474">
        <property type="protein sequence ID" value="PHX54474"/>
        <property type="gene ID" value="CP500_015935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025938">
        <property type="entry name" value="RRXRR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14239">
        <property type="entry name" value="RRXRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRXRR" evidence="1">
        <location>
            <begin position="3"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="344" mass="40077" checksum="5CD673F745AB5A65" modified="2018-01-31" version="1">MFVPVVDSENRPLMPTTSSRAKRWMCSGKATPFWIKGVFCVRLNVEPSNTDRQPIAIGIDPGSKREGFTVKSKSHTYLNIQTHAIDWVKDHVEVRRNMRRARRLGRSPCRQNRANRLVNKNRIPPSTKARWQWKLRIVNWLTLMFPISTIVVEDVKARTWKNGRKWNVSFSPLEVGKHWFYSEIIKIAHLEIKSGNDTYNLRQELGLKKSKQKLSNKFEAHCVDSWVLANWYAGGHTQPDNTKLIEVIPLEFHRRQLHRLQNSTGHIRPRYGGTLSVGFKRGSIVKHPKYGFCYVGGWQEFPTKKDPYRKTISLHDLKTGKRLCQNAMPIDCKFLSYNSWRIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY84</accession>
    <name>A0A2G4EY84_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000101">
        <property type="protein sequence ID" value="PHX54438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54438">
        <property type="protein sequence ID" value="PHX54438"/>
        <property type="gene ID" value="CP500_016135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="308"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="532" mass="58647" checksum="3F94B60F573A7E84" modified="2018-01-31" version="1">MNTYYFLPTISEILASEGSENDLSPRDTRLAAENNRPRCSGSRGASRLKAEQEWYGAIATLNQMLDRQKPAQTTDSLLPNSCQGLVLSGPSSVLTDPALASGFANWIFTSIPDNDAALWSFRARQSLALLPAADVQISVPTAAPALALASGDPLANEQFCLVLTATFSLVMVLGENAVGIPAFLFSFDPQVVAKAWEVLRHRVTDSENLLGNSDGEINLAISQLTHNSTKLDALFEQFSPVDPNYKIVTNFSRLLLNNLPIWKEETGRIKDEIIDEGWRRRHEKLQAKNLNCKSPIPHATKEVELLQAIAHEVRTPLSTIRTLTRLLLKRPKLDAVVIKRLEMIDSECTTQIDRFGLIFRAVEMEMSQAKNSAVQLTVMSLGEVLLHSIPRWQKQASQRNHTLEVIVPKKLPAVVSDPTMLDQVLTGLIENFTRTLPSGSQIQVEVTLAGDQLKLQLESKHLSDTEGESTFLPAANTPLRSIGPLLMVQPETGSLSLNLSVTKNLFRAAGGKLVIRQRPQKGEVMTVFLPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYE6</accession>
    <name>A0A2G4EYE6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate/guanylate cyclase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54553">
        <property type="protein sequence ID" value="PHX54553"/>
        <property type="gene ID" value="CP500_015480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="124"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="346" mass="38600" checksum="9ACC7C47F6F06BDF" modified="2018-01-31" version="1">MPHIHYLPDDRAIKVDDDDIILEASLRGGIPHTHICGGSARCSTCRVLIVEGLEFCSPRTWPEAELAQKLRLDPEIRLACQTQIAGGDVILRRLAIDSEDLESFNDQMAGKSISPPVGQEKKIAILFADIRGFTPFAESLLPYDVIYVLNRYFQKMGYAINRNGGMINNYMGDGFMALFGLENSETAAQQAVRAGVEMLEELEKLNPYFENLYHHRLRIGIGIHYGLVVVGNLGATKSQTVTAIGDAVNLASRIESANKQVGTNFLISEETYAEVKKLAIVNRRVSVQIPGKSGEYPLYEVVGMPPLPIEIEEIGRFKKKSIFQALLKRWMGLFAGVRNWIRKIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYF4</accession>
    <name>A0A2G4EYF4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54562">
        <property type="protein sequence ID" value="PHX54562"/>
        <property type="gene ID" value="CP500_015525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05483">
        <property type="entry name" value="retropepsin_like_bacteria"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034122">
        <property type="entry name" value="Retropepsin-like_bacterial"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="214" mass="22569" checksum="3C54738948ACA7FD" modified="2018-01-31" version="1">MPHKSALPLLSNLYKNQRSAQNLPKPLLVLTTVISLSSSILVGTVANSSRALAQEIEGCFMRNSNGQTVNLSESVCGFLPKELTPATSTAANSGVFQAKIKRREANIPVIEVTFNGTQKFDMMVDSGASGTVITPAMAKALGVIPSGTVQAKTPNGEATFPLGRLTSIQAGGLAIKNVVVAISPSLDIGLLGHDFFGDKDITIKQDVIEFRSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYQ1</accession>
    <name>A0A2G4EYQ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HIT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54655">
        <property type="protein sequence ID" value="PHX54655"/>
        <property type="gene ID" value="CP500_014955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="164"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="288" mass="33307" checksum="37BA9D0D9A28DD47" modified="2018-01-31" version="1">MKKQHNKFSHLTAIERTYLSFPAKQLLDKNLLKGKILDFGCGFGNDVKLLQQKGFDVKAYDPYYFPEYPENKFDTIICFYVLNVLFPEEQANVLMEVSHLLKPGGKAYFAVRRDLKKEGFREHYVHKKPTYQCIVKLPFKSAHLDESCEIYEYVHYNHQRNSSNNCIFCNPHKHLILITESATAYAILDGYPTSKGHVLIIPKRHTANYFELPFREQSACWFMANKVQDILTKEFQPDGFNVGININKDAGQSRSHAAIHIIPRYRGDATGHKGGMRYVIPQVKNKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYT0</accession>
    <name>A0A2G4EYT0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54679">
        <property type="protein sequence ID" value="PHX54679"/>
        <property type="gene ID" value="CP500_014750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="30182" checksum="0AE7C5EE8CF625C0" modified="2018-01-31" version="1">MSEITLLHEIAHCPHARFCRENPAAEHPCSEIVNYQKSLNLDDFQVPEPWSGHIEKAPILFLSSNPSIGAGENYPNWSWSDDDMEDYFSYRFGGGRKEWIVNGTKSLLMDGTYSHAVKFWAAVRQRAMELFERDVLPGIDYALTEIVHCKSHKEIGVERAQNKCVEAYLLRTLELAGAKVIVVLGKRARKAIQSQFNIPEKISVSEAIKIGSSERFFAFLPHPNARSDRSFSKCFQDDELEKLRASLHLSSSLSLSSGIEGECFTALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYV2</accession>
    <name>A0A2G4EYV2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AbiJ_NTD3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54680">
        <property type="protein sequence ID" value="PHX54680"/>
        <property type="gene ID" value="CP500_014760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041427">
        <property type="entry name" value="AbiJ-NTD3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18860">
        <property type="entry name" value="AbiJ_NTD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AbiJ_NTD3" evidence="1">
        <location>
            <begin position="2"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="357" mass="41963" checksum="7903C815386FBE0F" modified="2018-01-31" version="1">MQITELTRRNIIEALISRDKISGRLELFEFLELTWKLSEMPSTDSRFKDASGDIWQHMVNNNDWDEDYLFFRCLDIFKLPDQRFLHFLEQVIHPMVRPSETQQAEYANLINSYLVNDGYRLNATEQMSGCPVYKAIRVQGGVPSPIKNLIFAAKGDKPEIVLVDAVSNDIRITRNEENCLVYKELVPSSGLFWSDLVKWWAAQTNADPISDETEKALRQRLYDSLDSEPERLLFDSYFQRIHSLMQEPPALIPQIYLHYDPYTLRERNGQKELPRQRMDFLLLLPNSQRVVIEVDGKQHYADQDKANPKLYSEMVAEDRELKLRGYEVYRFGGYELQRGQQVVEDFFRKLFVQKGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYZ0</accession>
    <name>A0A2G4EYZ0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54743">
        <property type="protein sequence ID" value="PHX54743"/>
        <property type="gene ID" value="CP500_014475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7159" checksum="F37223568DD51DBC" modified="2018-01-31" version="1">MQRNRRQILLQDRSPLHSPKLQLDRAIAQILTGIWASTSVAADFRPLWSIVKAVNYIRFINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ35</accession>
    <name>A0A2G4EZ35_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_014395</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54769">
        <property type="protein sequence ID" value="PHX54769"/>
        <property type="gene ID" value="CP500_014395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007895">
        <property type="entry name" value="MASE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05231">
        <property type="entry name" value="MASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="454"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="573"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="823" mass="91004" checksum="8483606F82313FF7" modified="2018-01-31" version="1">MQKKFLNTIKGHSWRYFLSVGAIALMYFLASKFAISTLTLSPEVSPIWPAAGIAQVALLLFGRQLWPGIAIGGFMFSMTNPSANIATAFISASGRALQAWTGTYLLQKINFSAGLDRLKDVLGIVGLAAFGSTLINSTIGSVVQCLTGLSWSNFGKIWGTWWVGDAMGILLIAPLVLTWREFPSVKTNRQQIVERAIWLVLLLAVGWLVFCSRTRAAYARYPLEYLPFPLVVWAAFRFGQRYTALSNFILCGFAIWGIARGSGPFLKHASSIPQALLSLQAFIAVIAVTGLVLAATVAERRQAETFLRASEASLANAQRIAQLGNWDLDRTTQQLRWSDEIYRILRQSPGSFEPSLETFLEYVHPEDKELVKTSIEAALFQQQSYSIDYRLLLLDGCDRTVCEQAAVNSTYITSTVQDITDRKRAEAALRSSEERFSKAFHASPVGISICTLTDGCFLDANESFLRQLGWERQEFLGHTAEELTMFVNPEDERGITQTLQSQNSISNQEILIRTKTGEERDWLLSVELIHLGSTQCVLIMTSDITEAKRGEEFRRAALAAEAANRSKSEFLANMSHELRTPLNAIIGYSQILQEDAKDLGAEEFISDLKRISTAGQHLLAIIKDILDLSKIEAGRMKLDIETFSILNLVEDVAAMIALMADKNSNILDVRCTDDIGDMSTDLTKLRDCLFNLLSNASKFTFSGVITFAVTRQEVEITEESAVEEGYHGEPENNSPLISAKSPSQDWIIFTIKDTGIGMTPAQLARVFEPFTQADSSSTKKYGGTGLGLTITKKYCKMMGGDITAVSKLNQGSIFIIRLPAKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ41</accession>
    <name>A0A2G4EZ41_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54793">
        <property type="protein sequence ID" value="PHX54793"/>
        <property type="gene ID" value="CP500_014085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="4">
        <location>
            <begin position="53"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="3">
        <location>
            <begin position="273"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="406" mass="44987" checksum="903CEC64CC2CAC16" modified="2018-01-31" version="1">MIESLLNNETKTYSPPCSEAMAQRLLSTYGSPLYVYQADRLHQTLEHITRSIDYPHVQFHFATVTNGNIALLQLIEQAGWGLHANTPGDVFLGLKAGFSGDRIVYTGSNLNRVDIQQLIDWKIDRFNFDSLSQLRDFCEYSGSQGGYRRPEIGLRLNSPELTGDSRIGVHPAEFEKANEIAQQHGFSITGLHFYRGTGTNATAAFTQVIDRLIAIAQQLPDWRTLDFGGGFGYPYRGGAVFDWGEFGAAITERLSALSRPIELVIEPGRSAIAGCGILLAKVVSVKWLSDRQIVGVDTTVSNLSVPAVHGGYRAIATWETGDVSRYQTDICGNTTYSRDYLGRNCWLPKLQIGDAIAILDSGAYGYAMSSHFLHRPRPAEVLIDAKGDRLIRQREDYSILLNGQIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ49</accession>
    <name>A0A2G4EZ49_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54803">
        <property type="protein sequence ID" value="PHX54803"/>
        <property type="gene ID" value="CP500_014140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039564">
        <property type="entry name" value="Peptidase_C39-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13529">
        <property type="entry name" value="Peptidase_C39_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_C39_2" evidence="1">
        <location>
            <begin position="721"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="884" mass="96928" checksum="ACD2FC4CA6FAE033" modified="2018-01-31" version="1">MTNSTSILTYLGPQEIEANRATALVGIFDKNQVAAISATEGTNALNVQINPSTGTWNISLEKGFNNAGNRTLQVKATDKTGKVIGEQTFNIKVNPATNSSEPLLMLIVLQNTTFKAGTVASASLNDQQKADTIAGQTYVVTDYELDDRHLKVNLKNPIAPLGKSGYFYEEHVLITKGAKVLRFDRTDLPTPPPGMQLLWVVKKSKLKLSPADSAILAQNQKVDLSQGETLNILGYACIENHFRVTFDRAIPNFGNSGFLYSQHVQILQDGRGIPFDKNAVTMTVLKTTAFKKRPVDAATLQPPEKITLPAGMIYGVSGFSIEQGHIKVSLTENLPPFGNTGFVYPDFVQFSRGGKSFNPAPNLTYQGPTEVLIDQAIALSGTFDKQEAVKVEVIAEDKFALNVTLNQTAGTWRVDLPQGFKVPGARWLRLRATDSKGNVTGSQVIYLTVSSDPLTVGKGLTLKILSDTLFKVAPVDSSRLDNQQKILVKAGQTLAVSKYGFIDGHLKVVLDAAIIPIGTFGYFYESDVQLAKGPKILKFDLADVPNTNVSAQLLVTQTTQIKGAAQDSPKLPANQVADLILGSTYAITGYACISGHFRVTLAESIPDFGNVGFIYWRHVQIKKLGKEVTFDPDALTITMLQPTVFKKQPVDANKLSATERVTLPLGRVYGMESYGLEGSHLKVSLTEELPNFGNTGFVVPTSVQFKRGDKVFDPVPNNVELNVPYFSQRDNPRFDWSTCNVTAIAMVFYYYGVRSKWGGQLEDELLQWCFDYAGQGSQTDHNVLSALIKAYGFKTSFSTTRKWADVRSELLNRRPIVLAGDFTASGHIITVIGYNSQGYIAQDPWGDALTGYRDTEGRKLMYPYNYINQVAGPDGNVWAHFISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZF3</accession>
    <name>A0A2G4EZF3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase S8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_013775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54900">
        <property type="protein sequence ID" value="PHX54900"/>
        <property type="gene ID" value="CP500_013775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07498">
        <property type="entry name" value="Peptidases_S8_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034054">
        <property type="entry name" value="Pep_S8_PrcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="SLH" evidence="4">
        <location>
            <begin position="583"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="4">
        <location>
            <begin position="647"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="4">
        <location>
            <begin position="707"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="775" mass="83083" checksum="D5736AE656A6A53E" modified="2018-01-31" version="1">MVQPNQPDTSTLLNYQGIGVPDQSLALILQRGGDEVLLSKVPDRFTVRPSSTASASNPWLANTEAKFNQPIGNSNLEEYLVAPALLNTAMQAARASDAIAFASHVYSPAKNPGAFFYLTDRITIQFGEQVDEQSRNAIVNAAVLKIVGQVEGIRNTFICEVTKQATENPIKIANRLTRYAEVLVAEPNIIVQTQQHYIPRDPLYSRQWYLNNKSGSQMVAGSHIFAEKAWDITRGVRSIVIAIADDSVDMTHPDFQGQGKIVFPLDLKDNDLSPMPVLDSDNHGTSCAGVAVAEENGKGIVGVAPGCALMPIRTTGYLDDDSVEQIFNWAIEKGAAVISCSWGPSAVYFPLSLRQSAVITKAATQGRGGRGCVIVFAAGNANRPVNGTINEKGWPNDIIKGQTQWLSGYAVHPDVIAVAASTSLNKKSAYSNWGSSISVCAPSNNAPPGTWMQQTGYISTPPEVTQDLPGLGVFTADRIGIAGYDVGDYTDSFGGTSSATPVVAGVAALILSANPRLTAREVRGILEQTTDKIVDPDPDPQLGIRMGTYDLKNRRSDWFGYGKVNAFQAVQAAVRKGGGNPNIGDARFNDISGHWAQKFIEALAAANMISGMPDGSFRPDESLNRAQYASLLVSAFSPIPKAAATNFIDVSASFWARSAIERANRAGFLSGFPGLKFGPNLNLTKTEAIVSLVNGLELKGGNADTLKVYTDRAQIPNFALSAIAAATSLKIVVNYPSRDWLSPQRDVTRGEISALIYQTLVAIKRAKAIDSPYIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZG0</accession>
    <name>A0A2G4EZG0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54878">
        <property type="protein sequence ID" value="PHX54878"/>
        <property type="gene ID" value="CP500_013660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13262" checksum="670D301345FAB9CE" modified="2018-01-31" version="1">MVKSVPYHPFLIEQLKDPVYAAGYLTLFLNEQEEGDLDIGIFPSALKDVFEALGEPNMSADEAKLHLEKLDVLLSQSGIATIYALANWLKVLGLKLSVAVAEDEGEEESSVSAVELVEVGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZJ6</accession>
    <name>A0A2G4EZJ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Restriction endonuclease subunit R</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54935">
        <property type="protein sequence ID" value="PHX54935"/>
        <property type="gene ID" value="CP500_013335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="212" mass="24437" checksum="F35D4A5EC78006DB" modified="2018-01-31" version="1">MVLTIQARNVALNDLETNFKIEWIEDDQFFREWQDDLPQISEAEKQRLDRVKASYRNLLKRPPLLENTVKMVVLSPFLDLANFYLAPFHVTSEKSVEIVDEDEGMIVRGQLDVLALFQEFWVVVIESKKAAFSLEVGIPQLLAYMLAHLNSDRPTYGLLMNGADFLFVKLVKRETAQYAFSRKFYLFNPGNDLYSVLSILKRLGELNAGNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZJ8</accession>
    <name>A0A2G4EZJ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54607">
        <property type="protein sequence ID" value="PHX54607"/>
        <property type="gene ID" value="CP500_015120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="28"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="22322" checksum="F4ADE7DDBA7DF33A" modified="2018-01-31" version="1">MITTLEKLDRLDEPILIDGLTWREFQVVEHLLSRPGVRLSFLDGVLEIRRIPGRKHETVKHRISTLLDLYLEFVGIDFTPTGSVTLESETGMVKREADLSYELGANRELPDLVVEVVVTSGGIDKLEAYKRLQIPEVWFWENGVICLYSLGDDGYMEVDRSFVLSDLDIVLLGRCINIENHLQAMREFRQAIQCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZV6</accession>
    <name>A0A2G4EZV6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="5 8">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_012800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>NAD(+) + S-(hydroxymethyl)glutathione = H(+) + NADH + S-formylglutathione</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>NADP(+) + S-(hydroxymethyl)glutathione = H(+) + NADPH + S-formylglutathione</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="5 8"/>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55041">
        <property type="protein sequence ID" value="PHX55041"/>
        <property type="gene ID" value="CP500_012800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106322">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase NAD activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106321">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase NADP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006069">
        <property type="term" value="P:ethanol oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="9">
        <location>
            <begin position="12"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="369" mass="39123" checksum="BF147BF761E5E289" modified="2018-01-31" version="1">MKVKAAVAYSAGKPLSIEMVDLAGPQAGEVLVEIKATGVCHTDAYTLSGADPEGLFPAILGHEGAGIVAEIGAGVTSVKVGDRVIPLYIPECRNCEYCLSRKTNLCQAIRLTQGQGVMPDGTSRFSIDGQKIHHYMGTSTFANYTVLPEIAVAKIRDDAPFDKVCLIGCGVTTGIGAVINTAKVEPGSNVVVFGLGGVGLNVIQAARLVGANMIVGVDLNSEKRQMAEKFGMTHFVNPSEIEGDLVAYLVDLTKGGADYTFECIGNINVMRQALECCHKGWGVSVIVGVAGAGQEISTRPFQLVTGRVWKGTAFGGAKGRTDVPKIVDWYMDGKINIDSLVSQVMPIEQINQAFDAMHKGEVIRTVLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZZ5</accession>
    <name>A0A2G4EZZ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Paraslipin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55074">
        <property type="protein sequence ID" value="PHX55074"/>
        <property type="gene ID" value="CP500_012690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="1">
        <location>
            <begin position="19"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="21511" checksum="D9A87AD095F47F76" modified="2018-01-31" version="1">MYQYFLMVLFAITGVSLASSVKIVRQGDEALVEIFGKYDRKKLEPGLTFLIPFVETVAYKQTLREQMLKLPPQQCTTRDRVSITVEFIVYWRIIDLEKASYKVQNLKEAMLNMLILSIRTHIAKLAVEELYTARNEINNALVEELDTTTDPWGVKFTRVELRDFAIGSKVIQPTSFERKEVQKARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F050</accession>
    <name>A0A2G4F050_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Urease subunit beta</fullName>
            <ecNumber evidence="2">3.5.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Urea amidohydrolase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ureB</name>
        <name evidence="3" type="ORF">CP500_012215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2 H(+) + H2O + urea = CO2 + 2 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20557"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the urease beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.5" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55142">
        <property type="protein sequence ID" value="PHX55142"/>
        <property type="gene ID" value="CP500_012215"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00258">
        <property type="reaction ID" value="UER00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035550">
        <property type="term" value="C:urease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00407">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01954">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002019">
        <property type="entry name" value="Urease_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036461">
        <property type="entry name" value="Urease_betasu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00699">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51278">
        <property type="entry name" value="SSF51278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00192">
        <property type="entry name" value="urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="11377" checksum="F379AA5EE2668DD8" modified="2018-01-31" version="1">MIPGEMIVLAGEIELNAGRETVRLLVGNTGDRPIQVGSHYHFYETNEALEFNREQAKGMRLDIPAGTAVRFEPGDEREVQLVPFVGSREVYGFNGKVNGELDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F056</accession>
    <name>A0A2G4F056_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55154">
        <property type="protein sequence ID" value="PHX55154"/>
        <property type="gene ID" value="CP500_012285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="11178" checksum="BF163941342DF28F" modified="2018-01-31" version="1">MSIQEKIVDQLKSFSEIELQEILKFADFLLWQRRNQEVASPSDETANSESENIGEEALVHYVGGVLVVKAGLSQTEKMMNWNTIVNEMRAERMEKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0C0</accession>
    <name>A0A2G4F0C0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55196">
        <property type="protein sequence ID" value="PHX55196"/>
        <property type="gene ID" value="CP500_012105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="224" mass="24644" checksum="24A2412AC3425C0C" modified="2018-01-31" version="1">MKINQVKADLDLAIEHQNVPVAHEGLHNFLYSSDEEHGAATAIPALENDGTQIISIATWRDLATNAKVAGVYAVINTSHQTQYIGYSRNILLSLNGHIAQNGSENCAFLRVQTFKFPKREEMENLRDTWIAELGNIPPGNDADSEMWASTVGQAARAAMSADEQKAYEEKKLKLRKAMADSTLTKELEIAAKSADERGKDLESAVNDDWSAIIQSQTQETKASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0D7</accession>
    <name>A0A2G4F0D7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55232">
        <property type="protein sequence ID" value="PHX55232"/>
        <property type="gene ID" value="CP500_011880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="87" mass="9536" checksum="EE246ED7C82B436F" modified="2018-01-31" version="1">MINEYGSTEATVDGTICIWSEFVLCIMGGHSSTTRGKLGASTGVFLLPGETFNLPGHFRIGLGVEPPFFQKAMNEFENFLINYQQGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0F7</accession>
    <name>A0A2G4F0F7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54937">
        <property type="protein sequence ID" value="PHX54937"/>
        <property type="gene ID" value="CP500_013345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="271" mass="30250" checksum="214FD1A312C2068F" modified="2018-01-31" version="1">MTKLIEIASYPFFLRIPIFLVALLSIWLPFAVPIYLLVKDSNLATILTMALLFTEFLFLVRLWGKQVYGENQVLKSYGLINSRQNGFEFLIGLAIGLLLTFSLFAVQGLFGFVSWQNSDNLPRIIAEGLLSALGVGFAEELVFRGWLLEELERDYSDRISLWANSLLFALSHFIKPVAVMLRSWPQFPGLLLLGLILVGGKRSRQNRLGLPIGFHAGLVWGYYIINIGKLVRYSGSVPDWVTGVNGNPLAGAIGLLFLSILAVGIRQMSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0I0</accession>
    <name>A0A2G4F0I0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pyrG</name>
        <name evidence="12" type="ORF">CP500_011745</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55248">
        <property type="protein sequence ID" value="PHX55248"/>
        <property type="gene ID" value="CP500_011745"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="3"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="302"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="382"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="507"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="509"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="148"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="188"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX55248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="552" mass="61728" checksum="BE5394759D49CC03" modified="2018-01-31" version="1">MSKFVFVTGGVVSSIGKGIVASSLGRLLKSRDYSVSILKLDPYINVDPGTLSPFQHGEVFVTQDGAETDLDLGHYERFTDTSMSRLNSVTTGSIYQAVINKERRGEYQGSTVQVIPHITNEIKDRIHRVAKDTNPDVVITEIGGTVGDIESLPFLEAIRQFRKDVGRQNVVYMHVTLIPWIPSAGEMKTKPTQHSVKELRSIGIQPDILVCRCDRPLSLGMKEKLSEFCNVPEECVITAQDAKSIYEVPLMMEQEGLAEQTINLLRLENRQPDLHQWQTLVKRLYSPSHKMDIALVGKYVRLNDAYLSVVEALRHAAIAIGCDLNLHWINSEDLESGNIESYLKGMDGIVVPGGFGIRGVDGKIAAIQYAKHHQIPFLGLCLGMQCAVIEWARNTAQLEKANSAEFDQNTPNPVINLLPEQQDVIDLGGTMRLGLYPCRVNPDTLAFKLYQQQVIYERHRHRYEFNNAYRNLFLESGYAISGTSPDGRLVEMIELPSHPFFIASQFHPEFQSRPSSPHPLFQGFMQAASIQRKHGFPEAQGEELVPETVAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0L1</accession>
    <name>A0A2G4F0L1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55299">
        <property type="protein sequence ID" value="PHX55299"/>
        <property type="gene ID" value="CP500_011690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="12"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="187" mass="20963" checksum="FB17DFB9A8A8B470" modified="2018-01-31" version="1">MVQVQTKTLTMSEFLKLPETEPASEYINGEIIQKTMPQGKHSRIQGELVPAINVVVKKPKIALAFPELRCTFDGRSIVPDVTVFTWDRIPVDENGDVANVFEAYPDWTIEILSPGQSQTKVTGNILHCLKNGTKMGWLIDPMVRSILIYPPGKQPELLAKLEELLPVPDWAAELRLTVGDLFGWLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0S2</accession>
    <name>A0A2G4F0S2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">K(+)-transporting ATPase subunit F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">kdpF</name>
        <name evidence="2" type="ORF">CP500_011375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55338">
        <property type="protein sequence ID" value="PHX55338"/>
        <property type="gene ID" value="CP500_011375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043462">
        <property type="term" value="P:regulation of ATP-dependent activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011726">
        <property type="entry name" value="KdpF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09604">
        <property type="entry name" value="Potass_KdpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02115">
        <property type="entry name" value="potass_kdpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10227" checksum="C43680B5B0ADD51C" modified="2018-01-31" version="1">MKRNDLLNDILPRDFQETIELAQMLWKRHPIPVQLFLVMCFNLIIAPAVYAAADENLTKKAAWGLSLLGLVIIALAIYLFVVIFQPERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F149</accession>
    <name>A0A2G4F149_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55504">
        <property type="protein sequence ID" value="PHX55504"/>
        <property type="gene ID" value="CP500_010375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="50"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="224" mass="24657" checksum="8028A4E608808F96" modified="2018-01-31" version="1">MPAKVASNTSRVSPWLTSLLYPLGHYVVLPSYFGKIQITGQENLPKDGPVILAPTHRSRWDALMMPYSTGQKVTGRDLRFMVTADEVKGLQGWFIRHLGGFAVDIRHPAISSLRYGVELLVDKQMLVIFPEGGIFQDGEVHPIKPGLARLAIQAESIAPGLGVKIVPISIRYRPRIPRWGSPVKIAIGSPLSVMDYAKSGSTKKEARLLTADLEIALKSLDESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1D7</accession>
    <name>A0A2G4F1D7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55573">
        <property type="protein sequence ID" value="PHX55573"/>
        <property type="gene ID" value="CP500_010105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="187"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="290" mass="33116" checksum="5D5C045352B02434" modified="2018-01-31" version="1">MNDFRSEKTRLQSKPAILTQSWVIWEFSAVIETKGFKFETVNLHDILKAELQAQQVPIDVFYTNAGWIIEGAGNTPKIDKDVRARVTANLRNSIYTNMQFIAGIDYFGDSNWADIQMMMIVQPEEPPKLPDPPIRPEAANIQPLIPDGALVVLALIAAGFFVSGNGGLQVLSIVGVIGAFVIYFKSNSDVAEKKRKYESQLARYQEENIERNRQIEKIKLEEEELKRNRLSRSFQWDDLRVLHTIMSRSVGKIIHNNMLQKGGIVQEFVHQTKNEEIIPESKKDILNEFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1K6</accession>
    <name>A0A2G4F1K6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromosome partition protein Smc</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">smc</name>
        <name evidence="5" type="ORF">CP500_009890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for chromosome condensation and partitioning.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55632">
        <property type="protein sequence ID" value="PHX55632"/>
        <property type="gene ID" value="CP500_009890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01894">
        <property type="entry name" value="Smc_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02169">
        <property type="entry name" value="SMC_prok_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="4">
        <location>
            <begin position="577"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="232"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="317"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="472"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="734"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1042"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="33"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1232" mass="139762" checksum="2EB874DB7C741B03" modified="2018-01-31" version="1">MVHIKRIELTNFKSFGGTTSIPVLPGFTVVSGPNGSGKSNILDGLLFCLGLSTSKGMRAERLPDLVNNAQNKRGTIESSVTATFALEGVGDEWFADDQDEDGYEDAADDLSEAEAVEIPEIEIPETQYNNNGKSSNRKSKIQNLKSDEWSVTRKLRVTRQGTYTSTYYINGEPCTLTQLHEQLNRLRIYPEGYNVVLQGDVTSIISMNSKERREIIDELAGVAQFDRKISLARQKLDEVKDVEERSRIVEKELISQRDRLANDRTKAEKYQKLRAEFQEKSQWEIVLKFRQLQKQEWKLREQIEAGDRNSTDLTEQLQTANTQIIAATAELDALNARVKALGESELLALQSTMATQEAERRQLQNRKQELETTAGQLAANIAQTEQEVRQFRQTLEQIEIEISYVKSQQGSFQEQRDASQQSLNESREVANAIASTAEVWVQQQTELHRQIETVQQSLEPERAEQAAIGERVDRLQSQIQEQNQSLQTLEQEIAAQKVQQSQLLTTKGIASLQVESLNQIVASNEQELQLQQETQTRLLEEQRERQRTLDKLEMQFQAAQEATGTFTAKIIVQSGIYGICGLVAQLGRVEPRYQLALEIAAGGRMGNMVVEDDRVAAQAIELLKQKRAGRMTFLPLNKIRGGRFSVNENLRRAAGFVDAAVNLIDCDSRYNEIFAYVFGSTVVFSNLSDARRYLGQYRIVTLDGEILETSGAMTGGSSTNRSTLHFGTVDANEAQVEARTIASLQERLEEIERILARCKIAIERASVALKTNSQELMEAKQNLRENQLRLEQLATETQKLVAQQEQVRSQITKNTQELTNSQSRLQLLERELPVKETQLQEYRQTLAQLEESNSHSEWQQMQSGLRAQESQLQERELALRNIQQRLVDLENQFGRLEEKIQAGSQKLQEWQMQQNTSADAINQIVSQQSAIEQQIVEAKAAVAEIEEKLGVQKGERDRAESQLREKHLAKQQLQWQLQKLHESQQERREQLAAVRDLLAAQRAEMPDPVPSIPENVEKGNLTELQQEVKAIAKRIQALEPVNMLALEEYNRTQERLQELSQKLTTLEGERTELLLRIENFTTLRRRAFKEAFDAVNENFQTIFAELSEGDGYLQLDDQEDPFSSGLNLVAHPKGKPVQRLASMSGGEKSLTALSFIFALQRYRPSTFYAFDEVDMFLDGANVERLARMIKRQSEQAQFIVVSLRRPMIQSAERTIGVTQARGAYTQVIGLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1P9</accession>
    <name>A0A2G4F1P9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55676">
        <property type="protein sequence ID" value="PHX55676"/>
        <property type="gene ID" value="CP500_009725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="348" mass="36731" checksum="37A3BAAEABB795E2" modified="2018-01-31" version="1">MTQQNPRELLKQGDPQAIASSINRTLKPKGINAEVTRDNGCLHIFLESGKVPDQMVLVDFIRTGMTKLGLESIHTVKVYGIETGQDSPAWQEEIELMPKEPILYENDSSMPNDSVGLDDQPESEEYYQEEEFDRDDDEEDDDEEEETPPPKKQLPKWAIPVGLLVPVAIVAGLFFTGSPPFSSSSTTEPTAPVPPSPSSKATSGASKPASPSPSASKGVTPAASPASPAPAAAPNAATKPASPAPAGTSPVPKTTSPAPATASPTPKAAAPKSDTWREAVNQAQSAAILAQTAQSQAEWNAVASEWQKAVVLMNAVPTTSPNHQKAQQKAAEYKSNLVIANRRAAAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1U7</accession>
    <name>A0A2G4F1U7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Signal peptidase I</fullName>
            <ecNumber evidence="3 6">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">lepB</name>
        <name evidence="10" type="ORF">CP500_009500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 6"/>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55719">
        <property type="protein sequence ID" value="PHX55719"/>
        <property type="gene ID" value="CP500_009500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="9">
        <location>
            <begin position="45"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="213" mass="24068" checksum="7E746CEE698EE799" modified="2018-01-31" version="1">MTSDKSNLSKKVAENQPDTSTLESLSGVEGLSTRTSWQKAWNSQRENLQIVIIALALAILIRALIAEPRFIPSDSMLPTLHIGDRVVVEKISYYLEPPKTGDIVVFSPPEQLQEQGFTQDQAFIKRIIGLPGQTVAVKQGLVYLNDKPLVENYIAEPPKYQWGPYRVPENQYFVMGDNRNNSNDSSRWGFLPKQNIIGRAVVRFWPLERIGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1V6</accession>
    <name>A0A2G4F1V6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_009280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CbxX/CfxQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55741">
        <property type="protein sequence ID" value="PHX55741"/>
        <property type="gene ID" value="CP500_009280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041627">
        <property type="entry name" value="AAA_lid_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000641">
        <property type="entry name" value="CbxX/CfxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17866">
        <property type="entry name" value="AAA_lid_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00819">
        <property type="entry name" value="CBXCFQXSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="345"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="621"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="846" mass="95629" checksum="F6C768D934A228F1" modified="2018-01-31" version="1">MTVERVTSGLNLQSGDRFLVLYGANTSDTFCSQDLLLRNIEQVLHEYLRCEGYQRILFYSGTKKLYFLDEKSRARSRLQPKSAANSASSQPMRFRGALGNKGGLLGKQSAQTNTPATPTPAAPNSSPRLQDTQILPIFETAMRESSQQSAIVFSNAEDLANFDNRRELFGRIVDWSRFPPNNRNLCIFIFHHENRTTLQEFCQRIGFTFLANLANNGDDSNSRAVNFVHLSAPDAGEIRALRDYFRLEHRKVVDWNGADKLCSWIAAENKPLKHWCDRFETARQISLTEARRLGWLSADMNTKPALERLEEMTGLAAVKNTIRRRMQVLEIERERLQQGISSEPIRLHVIFKGNPGTGKTTVARLIGEIYRDLGLLKRGHLKEVGRQDLVAGYVGQTAIKTNEAIDAALDGVLFIDEAYTLTQGGDQFGKEAVDVLLKRMEDDRHRLAVIVAGYPDEMAEFVAANPGLQRRLTEIVFEDYNPAELLAIFQQRVARVRCSITPDLEVALMNLFGELYQRRDRTFGNAGLVENLFNLMDELRSQRVIEQKCDRLLEPFQVADLPAEYRQESRKDEAILQELLQELDRTIGLHSVKAAIGEIVNSQIANQRLREAGMLTKNSTETRHMLFTGNPGTGKTTIARLVGRIFKALGLLRKGQFVEADRRSLVGRVVGETAQKTAEAIESALDGVLFIDEAYALSRSESGIDFGKEAIDTIVPMMENQRDRLIVILAGYSREMEQFMDANSGMASRIAYKIEFPDYNGEELHQIFLSMCQGDGWICPPDVSARLQAVLMAAYQNRGRNFGNGRSVRNFYEKMVNRLKSRMVRDNLIGEAMRRFALADIPDWED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1X0</accession>
    <name>A0A2G4F1X0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55760">
        <property type="protein sequence ID" value="PHX55760"/>
        <property type="gene ID" value="CP500_009160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="SSF101967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="6230" checksum="B4F61D16E1810859" modified="2018-01-31" version="1">MGHGELGMGNWALGMGNWAWGMGHWALGMGNGALGIGHWAWGIGHWALGMGNWALGIGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F216</accession>
    <name>A0A2G4F216_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55517">
        <property type="protein sequence ID" value="PHX55517"/>
        <property type="gene ID" value="CP500_010445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="8"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="339" mass="36859" checksum="432E5530A9A88B23" modified="2018-01-31" version="1">MAATDFKDYYAILGLDKTTSADEIKKTFRKLARKYHPDMNPGNKEAEARFKEVNEAYEVLSDPEKRKKYDQYGQYWKQAAATTGGWPGAGGYGGAAPTDFGGVDFSQYGSFDEFINTLLGRGGGPGASASAGRNGNWNYRTTTGGPTGFGGFEDFAGYENRATGISLNTEVAISLTLGEAFRGTSKRVATGEVSIPAGVKTGSKIRVKGKGQVDPYTKQQGDLYLKVEVLPHPFFQFDGENLVCEVPITPDEAVLGASIEVPVPEGMITVKFPAGMRSGQSLRLRGKGWPKPKKDERTDLLVKIAIVPPKEITTVERECYEKIQANRTFNPRSNLNGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F289</accession>
    <name>A0A2G4F289_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55587">
        <property type="protein sequence ID" value="PHX55587"/>
        <property type="gene ID" value="CP500_009915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="18510" checksum="8BAAC788F463E6D5" modified="2018-01-31" version="1">MTRRTLVDEEQLLDQLDLVRINLPIAFQEAELIIRHKDDLLQEAELYAQEVIEAAEQRAAEILNDMGLIQQAKVEADQLRQQVLLDCEAIQQATLAEVEQIRYQAQEELAEMRARVIAECEEIQNGADDYADQVLDNIEHKLSDSLRVVRNGRQQLDNVSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2F7</accession>
    <name>A0A2G4F2F7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55940">
        <property type="protein sequence ID" value="PHX55940"/>
        <property type="gene ID" value="CP500_008185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="230"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="43013" checksum="CC818D1D0C681865" modified="2018-01-31" version="1">MPDTQPLTITLPPLRITMTDQQQVNLEWLTQNLPNLLTQSKPQVPDNMKQWVAANKLLNTPDAEIIQILISTGIDAETATAEVTQISSHPYFQAGSQYVQLLQKLESQLSINNQLAALSSKFGTIERKSSLSREYFLENYYAKNTPVIISNIMHNWKALQLWTPEYLQQKYGDAAVEIQANRNSDPDYEIKVHNHKKTVLFREYVDMVVNGGPSNDCYMVANNQTLEREEFKPLFNDIEIFPEYLNPAETSGRVFFWFGPKGTITPLHHDPVNLILAQVSGRKLIKLISPQQTPLLYNHVGVFSKVDGENPDYEKYPLYRDAKIIEVILEPGEAIFIPVGWWHHVKSLDVSISVSFTNFVFPNYYEWKYPHINW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2G5</accession>
    <name>A0A2G4F2G5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55951">
        <property type="protein sequence ID" value="PHX55951"/>
        <property type="gene ID" value="CP500_008240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8490" checksum="44C4A84757EB25BF" modified="2018-01-31" version="1">MYCSYKNACYLDNKPNQKPIANFCGFRLKVKQRSGFLYTVCLNYLADCIDKHSFWFYVKQQSNRQVDICAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2N1</accession>
    <name>A0A2G4F2N1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55995">
        <property type="protein sequence ID" value="PHX55995"/>
        <property type="gene ID" value="CP500_007865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="11"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="16588" checksum="C324DBB8566C1E32" modified="2018-01-31" version="1">MSAQSQVKPIEILLIEDSPSDADLAMEALSHGKILTNLHFVEDGVEAIKFLRKKAPYITVPRPDLILLDLNLPKKSGVEVLKEIKTDPNLKLIPVLILTTSAAQEDIIKSYSLHANCYITKPVDFLQFTNVVRLVEEFWLTVVKLPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2S2</accession>
    <name>A0A2G4F2S2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55757">
        <property type="protein sequence ID" value="PHX55757"/>
        <property type="gene ID" value="CP500_009140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="21751" checksum="718CCFDF45444A55" modified="2018-01-31" version="1">MTDPNMTEAEIVDVTPETTAIVKKEMPEATEEAIAETAVLFEAIKKRAAAEVQAAGDLTREAYLKAVQKAQLALAKNKTIAQERMTDAVGLIQKEAEKNWLVVDAIKTRAQSQVQDAGVVSREAYLKAVRQAREAVEKNQFIERDRIEQAVDQIQKESEKNWHVVVGEIESIGTRLTDASKSAWNALTKFFDKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2T9</accession>
    <name>A0A2G4F2T9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56055">
        <property type="protein sequence ID" value="PHX56055"/>
        <property type="gene ID" value="CP500_007430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="12135" checksum="B1120DB010B5A8D2" modified="2018-01-31" version="1">MSEFLDFLRHQFAYVAVGEFKPGKFKAAEELFAKAVATYATGFKGAYLLQLPNTDKGIAIIFWESVEEMTTNQSEAYQAILKQMTPLFAKIPDTDVYEIVSEIKPKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2W6</accession>
    <name>A0A2G4F2W6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B</fullName>
            <shortName evidence="10">Asp/Glu-ADT subunit B</shortName>
            <ecNumber evidence="10">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gatB</name>
        <name evidence="12" type="ORF">CP500_007220</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56089">
        <property type="protein sequence ID" value="PHX56089"/>
        <property type="gene ID" value="CP500_007220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="Apn/Gln-ADT_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042114">
        <property type="entry name" value="GatB_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GatB_Yqey" evidence="11">
        <location>
            <begin position="345"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX56089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="494" mass="54207" checksum="4F2F806EDA0558FB" modified="2018-01-31" version="1">MTAAAKVKIQYEAVIGLETHCQLSTKTKIFSSSSTEFGGVPNTNIDPICMGMPGVLPVLNEKVLEYAVKAGLALNCEIASYSKFDRKQYFYPDLPKNYQISQFDLPIATNGSIEIQLVDQSGNSTRKKIGITRLHMEEDAGKLVHGGSDRISGSNYSMVDYNRAGVPLIEIVSEPDLRSGAEAAEYGQELRRIIRYIGVGDGNMQEGSLRCDVNISVRPVGREKFGTKVEIKNMNSFNAIERAINYEIDRQIQALETGETIFQETRLWDEGKQCTFSMRMKEGASDYRYFPEPDLPPIEVSSAQLADWQAQLPELPAAKRDRYETELSLSPYDARVLTDDKAVAEYFEQAIAAGAPAKQAANWVMGDITAYLKNEQLAIAEIPFQADNLAELIALIETGTISGKIAKDILPELLAKGGSPQKLVESKGLIQISDTGAIESAIDAVLAANPKELEQYRAGKTKLLGFFVGKVMKETGGRADPKLTNELLANKLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2X7</accession>
    <name>A0A2G4F2X7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56121">
        <property type="protein sequence ID" value="PHX56121"/>
        <property type="gene ID" value="CP500_007340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12844">
        <property type="entry name" value="HTH_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="12670" checksum="CB258096EDC74FF7" modified="2018-01-31" version="1">MEQTFGKLIRQARKDKGYSQRELAAMLSVDFTYLSKLENDRADYAPKEEVIRSLARNLDINEEELIFLAGRLPQQYEALLKQNPKEMQALFRRMQENPDWLKKSFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F310</accession>
    <name>A0A2G4F310_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NAD(P)H-quinone oxidoreductase subunit D4</fullName>
            <ecNumber evidence="9">1.6.5.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_006995</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.3" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56128">
        <property type="protein sequence ID" value="PHX56128"/>
        <property type="gene ID" value="CP500_006995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="3" id="KW-0874">Quinone</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="8">
        <location>
            <begin position="126"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="514" mass="54965" checksum="3E8DF185C8D607A6" modified="2018-01-31" version="1">MLSALLWLPALGAAVVGFLPGNMNGMRLRSIASAFAAAVFLLNIWLVTQFDPANSGLQFQEYLPWIPQLGLNYNLGIDGLSLPLVVLSALLTLLVIYGTGEAVARPQLYYALILLINAGIAGALMSQNLLLFVLFYEIELIPFYLLIAIWGGKQREYAAMKFLIYTAVSGLLVLAGFLGVALLSGSRNFDYSAIHTQDLSFNTQLILLTIVLLGFAIKIPLVPLHTWLPDAYVEASPATAILLGGILAKLGTYGLIRFGLQLFPETWSIIAPGLAIIGTVSVMYGALSAIAQKDIKRMVAYSSIGHMGYILVACAAGTKLALIGAVGQMVSHGLILALLFYLVGVIESKVGTRDLDVLNGLMNPMRGLPTASSLLVLGGMASAGIPGLVGFIAEFLVFQGSFSSFPIPTLICILASGLTAVYFVILLNRTCFGKLDNATAYYPAVTFGENMPALVLAGIIFVLGIQPAWLLKWSESTTNAIAATLPTDRNAQVAISYSLEFSALERDCWRINKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F313</accession>
    <name>A0A2G4F313_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transketolase_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56136">
        <property type="protein sequence ID" value="PHX56136"/>
        <property type="gene ID" value="CP500_007045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transketolase_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="11562" checksum="E520E9E3EC18E2B7" modified="2018-01-31" version="1">MLQLVLQASEKLSSQGYSVQVLSMPTVAPLDEQAIWQAAARTGKIISVEEHGIGGLGSAVAEVLALGEIPVKFRALRLQREAVKVAGSQTALRSRLGLSLEGIIEAAISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F334</accession>
    <name>A0A2G4F334_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lytic murein transglycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_006845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56156">
        <property type="protein sequence ID" value="PHX56156"/>
        <property type="gene ID" value="CP500_006845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="223" mass="24833" checksum="A31D829A7AEED720" modified="2018-01-31" version="1">MLNLKNLVYHPTACPNAILKNINLELPSQQMGLIVGRSGSGKSTLLEILAGLAEKTSGDIRWREQELTPEHLQQLGGLVFQFPERHFCGGTILEELRLGHPELGQEQINKAMTEVGLGHLPMRASPHALSGGQQRRVALAVQLIRQPHLLLLDEPTAGLDWSMRRQLVSLLAKLKNHWTLLIVTHDASDLLSVADRFWTLNHGDLQQVDRTKLEAKETSFVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F352</accession>
    <name>A0A2G4F352_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56190">
        <property type="protein sequence ID" value="PHX56190"/>
        <property type="gene ID" value="CP500_006690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="21335" checksum="FA2F2935E15F821C" modified="2018-01-31" version="1">MSKRRVQIVILCEDRQQEVFARHFLKKRGFGPFRFEVCPKGSQSGEQYVRTRYPVEVKAYRQKRKERIGLVVLIDADRGTLQERLNQLASVLAEDEQEKRESDEAIAIFVPKRNIETWIHYLQGETVNEEDAYAKFEKNEAVCKTYVENLADRCYAQDLPEDAPRSLQAACGELQRLLPLLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F383</accession>
    <name>A0A2G4F383_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56234">
        <property type="protein sequence ID" value="PHX56234"/>
        <property type="gene ID" value="CP500_006590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="8022" checksum="1DA1F02492575C67" modified="2018-01-31" version="1">MEPEYDLSKMKKRPNPFAKQLKKQVTISLGIDVIEYFETMAEEKGISSQELINLYLQDCVISKRQLSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F385</accession>
    <name>A0A2G4F385_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="3">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_006565</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56222">
        <property type="protein sequence ID" value="PHX56222"/>
        <property type="gene ID" value="CP500_006565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004439">
        <property type="entry name" value="Isocitrate_DH_NADP_dimer_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43504">
        <property type="entry name" value="PTHR43504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00183">
        <property type="entry name" value="prok_nadp_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Iso_dh" evidence="4">
        <location>
            <begin position="28"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="474" mass="52313" checksum="27437074A8D19EEC" modified="2018-01-31" version="1">MYEKIVAPTTGSKITFKDGLPIVPNDPIVPFIRGDGTGVDLWPASQKVMDAAVEQAYGGDRKINWFKIYVGDEACDVYGTYQYLPQDSLDAIKEYGVAIKGPLTTPIGGGIRSLNVALRQIFDLYACVRPCKYYDGTPSLHKTPELLDVIIYRENTEDIYLGIEWAKDSEIGIKLIEYLNNELIPATPEHGKKQIRLDSGIGIKPISKTGSQRLVRRAITHALRLPKEKQQVTLVHKGNIMKYTEGAFRDWGYELATTEYRAECVTERESWILGNKEKNPDISLEDNARQIDPGYDALTPEKQAKITQEVTDVLTAIWDSHGDGKWKEKIMVNDRIADSIFQQIQTRPGEYSILATMNLNGDYLSDAAAAIVGGLGMGPGANIGDECAVFEATHGTAPKHAGLDKVNPGSLILSGVMMLEYMGWQEAADLIKKGLAAAISNGEVTYDLARLMEPPVPELKCSEFAEAIIKHFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3E6</accession>
    <name>A0A2G4F3E6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-dependent succinic semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56290">
        <property type="protein sequence ID" value="PHX56290"/>
        <property type="gene ID" value="CP500_006350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07100">
        <property type="entry name" value="ALDH_SSADH1_GabD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044148">
        <property type="entry name" value="ALDH_GabD1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="3"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="455" mass="49260" checksum="092C4D476873A2EC" modified="2018-01-31" version="1">MAIATINPATGKTLKTFEPLTDAEIETKLELAQQAFNKYRRLPFEQRALWMQKAADILERDREIYAQMMTLEMGKTLKSAIAEIEKCALVCRYYAKNAAQFMADIAVTTDASNSFVRYQPLGAILAVMPWNFPFWQVFRFAAPTLMAGNVGLLKHASNVPQCALQIEAIFTEAGFPEGVFQTLLVGSDKVADIIADDRVKAATLTGSEPAGESLAANAGKNLKKVVLELGGSDPYIVMSSADLPAALSTAVTSRMLNSGQTCVSAKRFIVAEEIADEFIKGFVEKFEQLKVGDPMLPETDIGPLATPAILKELDNQVQACIQSGAKLLTGGRPLSENGGNFYLPTILTDIPINAAARQQEFFGPVALVFRVASIDEAIALANSTSFGLAATAWTTVSSEGDRFISELEAGAVFINSLVKSDPRLPFGGIKRSGYGRELSIQGIHEFVNIKTVWVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3H0</accession>
    <name>A0A2G4F3H0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56302">
        <property type="protein sequence ID" value="PHX56302"/>
        <property type="gene ID" value="CP500_006105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="14044" checksum="2A797ABD174F519D" modified="2018-01-31" version="1">MSLKLFIDQCVPKSIIQILRDTEHEVFVLGDYIPIESPDIIVIAKAQELNAILVSLNGDFADIVTYPPSSYQGIISIQLRNHPEIIPQLMARLTEYLSLHDSEEHYRGKLLLVEVYRIRIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Q7</accession>
    <name>A0A2G4F3Q7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56392">
        <property type="protein sequence ID" value="PHX56392"/>
        <property type="gene ID" value="CP500_005615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="28730" checksum="340830E217267A09" modified="2018-01-31" version="1">MERIDELRLKLEKYSDRTPKDELLCQLILNICSLSRDSPQRRRLMNRLLQQLQRLPKLLKSSHLFYYEAVNKTWEWLDNNLHNFDPRLSPIQDSLLIWINCHLKYRIYDLYAKKNQNIFPLDLEFLERSGFYNDCLDAQIEQIERQEKQALAREIAKYFDRDPEQKLRRCHPQNRPDCNCQFIVQRLFFQPSPEKMATIARQLNINTQTIRSFWKRKGLSKVQAIARQIAQKNSDVMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F409</accession>
    <name>A0A2G4F409_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavodoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56478">
        <property type="protein sequence ID" value="PHX56478"/>
        <property type="gene ID" value="CP500_005150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="199" mass="21566" checksum="D45D2B02CA32A564" modified="2018-01-31" version="1">MSNLAIVYFSGSGKTHLMAQAIAEGATQLLGVKVELLRIVKEQIVNGVWQDAEILEKLNQADAIVFGSPTYMGGVAGQFKLFIDAASEVWFRQEWKDKIAAGFTHSSCASGDKQGTLLYLAINASQHGMIWVNVGDLPSQFLEKDDGVNRLGSFLGVMGQGTDLSGVEAKLALDPGDRLTAFRFGKRIAEAAERWSQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F434</accession>
    <name>A0A2G4F434_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Cyanophycinase</fullName>
            <ecNumber evidence="4 8">3.4.15.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_004945</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[L-4-(L-arginin-2-N-yl)aspartate](n) + H2O = [L-4-(L-arginin-2-N-yl)aspartate](n-1) + L-4-(L-arginin-2-N-yl)aspartate</text>
            <dbReference type="Rhea" id="RHEA:12845"/>
            <dbReference type="Rhea" id="RHEA-COMP:13728"/>
            <dbReference type="Rhea" id="RHEA-COMP:13734"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:137986"/>
            <dbReference type="ChEBI" id="CHEBI:137991"/>
            <dbReference type="EC" id="3.4.15.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase S51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.15.6" evidence="4 8"/>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56506">
        <property type="protein sequence ID" value="PHX56506"/>
        <property type="gene ID" value="CP500_004945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011811">
        <property type="entry name" value="Peptidase_S51_cyanophycinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032067">
        <property type="entry name" value="Cyanophycinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02069">
        <property type="entry name" value="cyanophycinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR032067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR032067-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="32320" checksum="663DDDBE1EC16ECA" modified="2018-01-31" version="1">MQQLTSPAVPQNIPQRTKTSIMVIGGAEDKVHGREILNTFFHRSGGTEARLAIVPSASRDPEGISNRYRTIFDEMGVRAIKVVDIREREQAENPVWKDYLDDCTGVFITGGDQLRLCGLLADTPVMEKIRKETREGKITLAGTSAGAAVMGYHMIAGGGSGASPNRSLVDLANGLNIIPEVIVDQHFHNRNRMARLLSAIASHPDLLALGIDEDTCALFEGDDTIKILGKGTVTIVDSREMLYTNEPQIEATQPLSLFNLRLHVLCHGDCYNMSLGKAMPSSACSESGWPAECRTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F470</accession>
    <name>A0A2G4F470_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56535">
        <property type="protein sequence ID" value="PHX56535"/>
        <property type="gene ID" value="CP500_004610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="12787" checksum="F372D900CB742DD1" modified="2018-01-31" version="1">MERLNYSEVVQRILKHHVENRLNSKTEVHLIFDTERDRYQLLHIGWEDLSRVFGCIIYVEIKDGKIWIERDGTEIGVGNELVEAGVPKQDIVLAFKAPYRRKFTEFAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F484</accession>
    <name>A0A2G4F484_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_004725</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56556">
        <property type="protein sequence ID" value="PHX56556"/>
        <property type="gene ID" value="CP500_004725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="260" mass="28505" checksum="C1DE5522CCD49389" modified="2018-01-31" version="1">MTEPLIELKGISKSFGQSPILNGVDLKIYRGEALAIIGPSGTGKSTILRIIAGLLVPDAGEIFVQGQRRMGWVDDVADPIGIGMVFQQAALFDSLTVEENVGFLLYQHSKLPRRRIRELVEEKLEMVGLPKIGDRYPAQLSGGMRKRVSFARAIMANPDNARDNPEVLLYDEPTAGLDPIASTVIEDLIRDLQRAQGVCSTYAIVTHQQSTIHRTADRIVFLYQGKVQWEGTVSDIASTDNLLIQQFFSGSVTGPIQVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4C1</accession>
    <name>A0A2G4F4C1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LPS biosynthesis glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56596">
        <property type="protein sequence ID" value="PHX56596"/>
        <property type="gene ID" value="CP500_004465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06532">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="241" mass="27211" checksum="24DB6AB37DBE1CB4" modified="2018-01-31" version="1">MTKITDYFQGVYVVNLPERQDRYQLIVKELESAEMPLTPHKVEIFPAIRPDEAGGFPSIGARGCFSSHLAILKQAKKQGLSNILIVEDDLEISAKFRTDEAIIVEQLCQQDWDFAYFGHVEEVGEKSPVTLVPFSEGVMTTHFYAVNGKIFDRLLHFLEELQQRPPGHPDGGPMHLDGAYSTFRAQNPDVVTLIASPNLGWQKSSRSDIYPNPWFDRIPGIRQLVAAARTGKTWLKRRLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4H4</accession>
    <name>A0A2G4F4H4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Autotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56684">
        <property type="protein sequence ID" value="PHX56684"/>
        <property type="gene ID" value="CP500_004105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013794296" evidence="2">
        <location>
            <begin position="29"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="166" mass="17890" checksum="83A5F7125DF48558" modified="2018-01-31" version="1">MRLQNIKLLTSATLSVLVSALSVSPTMANPATLIAQTQSTSTANTESITGIVKSIVGDIITIRPENERYRTLRIQKCVLKITALVPGMKVKAIYRGSQVENLMVLAKYKVVPSPVASPATPRVEAPPAPEPITPRPAPAPRIQPQTPRPIPAPAPRVQPRPVRGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4L8</accession>
    <name>A0A2G4F4L8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56689">
        <property type="protein sequence ID" value="PHX56689"/>
        <property type="gene ID" value="CP500_004130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="256" mass="29199" checksum="651968479365B144" modified="2018-01-31" version="1">MKISVIIPAHNEEGCLEGTVRAIAHTLNLEAIEHEILIVNDNSVDRTLNICQELSETFPTVRYINNQPPNGFGFAVRRGLAEFEGDAVAIVMADASDDPRDLVAGYRQLQAGYDCIFGSRFIKGGFVVDYPIHKLAINRLANWFVKSIFGLRYNDVTNAFKIYRKEVIDGVQPILSHHFNLTVELPLKAIVRGFSYDVIPLRWYNRTAGISKLKIKEMGSRYLFIVLYVWLEKHLSRGDYHRSEIRTKILTTNEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4P2</accession>
    <name>A0A2G4F4P2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nitrate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_003585</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56709">
        <property type="protein sequence ID" value="PHX56709"/>
        <property type="gene ID" value="CP500_003585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02791">
        <property type="entry name" value="MopB_CT_Nitrate-R-NapA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041957">
        <property type="entry name" value="CT_Nitrate-R-NapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="8" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="10">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="727" mass="80580" checksum="516236BD74E5D7F7" modified="2018-01-31" version="1">METIKTLCPYCGVGCGLEIVPDKNQGWKVRGDRHHPSSQGMVCVKGATVAESIRTDRLLYPMMRDTLDQPFRRASWDEALDAIVNRIQTIRSTSGPDAICVYGSGQFVTEDYYVAQKLVKGCLGTNNFDANSRLCMSSAVSGYVQSFGADGPPCCYDDLELTDCAFIIGSNTAECHPIVFNRLAKYHKKNQNVKMIVVDPRRTPTAEAADVHLAIKPGTDIDLLNGIAYLLLQSESIDPKFIQESTVNFEEFVEVVKSYTPDFVASRCGISVGDLETAANYWQQSQRVLSLWSMGMNQSSEGTAKVRSLINLHLMTGQIGKPGCGPFSLTGQPNAMGGREAGGLSHLLPGYRSVKNAEHRAEVEQFWGIAPGTISPHPGRTAWDMITGLETGEVEMLWIAATNPVVSMPDLERTKAALLRSPFTVYQEAYNPTETSAYAHILLPATQWSEKTGVMTNSERRVTLCMGFDTPSGEARDDCHIFAEVGRRLGFAEQFAFENSADVYQEFVQLTRGRPCDMSGLSHEYLRQEGPQQWPCRENEPKHPAKEAKRLYTDRRFHTPDGRARFSAYHSRGLAEPPDPDYPFVLTTGRVYGHWHTMTRTGRTDKINQLHPDPFLEIHPRDAANLKIKEGDLLEVRSRRGKSQFPAKVTKAIVPGTLFVPMHWGSLWAEGAEANAMTHAESCPDSKQPELKACAVQLVRVDTEIGAEIETEIGEFNWAKSTVAVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4R4</accession>
    <name>A0A2G4F4R4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF760 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56762">
        <property type="protein sequence ID" value="PHX56762"/>
        <property type="gene ID" value="CP500_003905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008479">
        <property type="entry name" value="DUF760"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05542">
        <property type="entry name" value="DUF760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="12935" checksum="6534ECFA6D8D0632" modified="2018-01-31" version="1">MVFHPDFDNSNAKQTTDNPLLKYLQHQSPEVLDRVAKSVGPEIKEIISHNVQGLLGILPSENFNVHITTDRENLAGLLASAMMTGYFLRKMEQRMQLEENLASTSSIKPNSPQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4U4</accession>
    <name>A0A2G4F4U4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative toxin-antitoxin system toxin component, PIN family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56804">
        <property type="protein sequence ID" value="PHX56804"/>
        <property type="gene ID" value="CP500_003505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002850">
        <property type="entry name" value="PIN_toxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34610">
        <property type="entry name" value="PTHR34610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00305">
        <property type="entry name" value="TIGR00305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="136" mass="15462" checksum="0CF6C2004E76C5B8" modified="2018-01-31" version="1">MTNRFVVDTKVLISALLFKNSVPFRAIELAEKQGIILYSEATLNELEQVLNRKKFNKYLSLEDRQVFLLKFISASELVSITEKIAVCRDEKDHKFLELAVSGNANVIVTGDLDLLVLNPFQAVEIITPDIFIDRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F515</accession>
    <name>A0A2G4F515_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56836">
        <property type="protein sequence ID" value="PHX56836"/>
        <property type="gene ID" value="CP500_003295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="25"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="161" mass="17741" checksum="21419747B0F9938D" modified="2018-01-31" version="1">MTTLLIPTQSVPLTIELPAIEPMTVEQFYQFCLANGDLRIERTASGEVIVMSPAFSDTSNRNGKISLQLANWAEQDGTGETFDSSAGFTLPNGATRSPDASWIKLERWNALTEEQKASFAPICPDFVIELRSSSDTLKGLQKKMQEYSGSHCYAVQSKTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F519</accession>
    <name>A0A2G4F519_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56811">
        <property type="protein sequence ID" value="PHX56811"/>
        <property type="gene ID" value="CP500_003555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="454" mass="51563" checksum="A3C1C3B05B991D68" modified="2018-01-31" version="1">MSNSSPVTPGSTLEKRYRILRELGRGGFGRTYLAEDINRYNEHCVLKEFSPVVHSPKAAELFDRESSILYSLQHPQIPRFRELLRTDIGGSQALFLVQDYIKGQNYEEILISRQKQGKNFNEAEVTQLLFQLLPVLEYIHSKNLIHRDISPDNIIQHDADKLPFLIDFGSVKQIAATALFQSKGQSDTAIGKQGYSPTEQMRQGKVSPASDLYALAVTALVLLTGKKPDKLYDVNQRTWDWRSHITVSQNLATVLDRMLADNSGDRYQSAKAVREALKDPKLSQIGSIISQMVTINFVGRPFKNITQTVTNNHTPVNPNPQIVKNINIFKLIPWKAVASLSVVLLPGMLAFSVVKSGFTLPKLPEFPKFPELPQFSNTSLDAEIARQEKIGKRRKNLNIEQDIFYNQVDELFYNKYPELQGRTLTDKPEDAEIRQKWYEVAENFLDKLEKGGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F534</accession>
    <name>A0A2G4F534_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitrate ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56856">
        <property type="protein sequence ID" value="PHX56856"/>
        <property type="gene ID" value="CP500_003000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="52"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="350" mass="38758" checksum="DD6ECA20C113CEE7" modified="2018-01-31" version="1">MTGKAQTGTRQLLRRCWLTLTKWRSLSVLCVLTLAVSLIMNACSLAPQQLAPLRVGIVSWAGFDIALYAQEAGLFKQRGLDVQLIRFENNQDSTRAMLRGNLDANFTSLWDVMQSDSGNDKPVVLMVTNISHGADGIVAQPVIKSVANLRGKRVGSKLGTVNHLILLEALKLHQIKPEEVKIEDVSNEIAVDLMQNKRLDAAVIWQPLLGEMAQNIKGNIIYTTQEVDSLIIDTLASRSTITSTKKAELKQFIMAWFDIMSAVETKPNEVFQKVGKSLGQKSEAFAKDYAGLKKGDIAMQQQMFKSGRLPEAIAQMAKLLKSDPRAGKIPRQDVEINTEIVTTAINEWKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F594</accession>
    <name>A0A2G4F594_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Epoxyqueuosine reductase</fullName>
            <ecNumber evidence="7">1.17.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Queuosine biosynthesis protein QueG</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">queG</name>
        <name evidence="9" type="ORF">CP500_004425</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>AH2 + epoxyqueuosine(34) in tRNA = A + H2O + queuosine(34) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:32159"/>
            <dbReference type="Rhea" id="RHEA-COMP:10345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82831"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="1.17.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the QueG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.99.6" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56657">
        <property type="protein sequence ID" value="PHX56657"/>
        <property type="gene ID" value="CP500_004425"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052693">
        <property type="term" value="F:epoxyqueuosine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00916">
        <property type="entry name" value="QueG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004453">
        <property type="entry name" value="QueG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013542">
        <property type="entry name" value="QueG_DUF1730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30002">
        <property type="entry name" value="PTHR30002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08331">
        <property type="entry name" value="DUF1730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00276">
        <property type="entry name" value="TIGR00276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="175"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cob(II)alamin binding" evidence="7">
        <location>
            <begin position="239"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="311" mass="35219" checksum="0C0F8F30566A9921" modified="2018-01-31" version="1">MKTSTNSDRIKQKSLELGFHKVGIALVDEGTDQESQRLQAWLDKGYQGDMGWMANPKRQDIRASMPEVKSLICVAINYYTPHQRPESSEYAKISRYGWGRDYHKILHKKLKVLADWVRSQGEGIEARYYADTGPIQDKVWAQRAGIGWIAKNGNVISREYGSWVFLGEVLTNLELVPDSGHTQHCGTCTRCIEACPTGAITEPFVVNADRCIAYHTIENRAEKLPDEIASNLQGWVAGCDICQDVCPWNQRFAKPTDVAEFEPYPENIAPTLAELAEISDEEWNRRFTASALRRIKPEMLRRNAIANQTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5D6</accession>
    <name>A0A2G4F5D6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56948">
        <property type="protein sequence ID" value="PHX56948"/>
        <property type="gene ID" value="CP500_002930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="220" mass="23230" checksum="359CE53997977DB1" modified="2018-01-31" version="1">MLNVKVLSGSMIAVLLAIGSYLGAISTPGVAVARGGTNPLGEVANAAQKTPSASLTISDRTIGAAQVGMTFGQLKKALGSTAQFKVESPFMVDFDAVALSQSGKVQYRIIYAAATKLKDGDVIELLMTDNANYKTVQGVGPGMTLKQAEAIYGKATLSYNVDNEMRENVVFAKQPTNKIMFVPKAEGKQFAGVYGAGKGGFFQTKKYQSNAVIKSVMVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5F9</accession>
    <name>A0A2G4F5F9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56986">
        <property type="protein sequence ID" value="PHX56986"/>
        <property type="gene ID" value="CP500_002555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="55"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="406" mass="45583" checksum="81BDB684522B1459" modified="2018-01-31" version="1">METSPDISAAVRRLYDTFPFPPDPLSDEPPPGYNWRWSWPDAYSFCTGQKPPKLDIRILDAGCGTGSSTDYLIHLNPEASVTAIDLSSGALKVAQERCRRSGAREADFRHLSLYDADQLEGEFDLINCVGVLHHLPDPIRGIQALAAKLASGGLMHIFVYAELGRWEIQLMQRAIALLQGTQKGDYPDGVKVGRQIFASLPENNRLVKYEKQRWAGENLRDECFADMYVHPQEIDYNIDTLFELIDASGLEFIGFSNPGYWQLERLLGKAPELIERAQGLTERELYRLIELLDTEISHYEFFLGKKPVNKIDWSDDQALLAAIPELSGCMHGWPSQQVFDCNYQLLNLSSAEFEFLQACAPPPAPPCQGGEKEVQKTVGEILVDVEVGLDEVRSILSKQLILLTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5J6</accession>
    <name>A0A2G4F5J6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DALR_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_001990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57073">
        <property type="protein sequence ID" value="PHX57073"/>
        <property type="gene ID" value="CP500_001990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DALR_1" evidence="4">
        <location>
            <begin position="173"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="321" mass="35953" checksum="24254C5167CD0472" modified="2018-01-31" version="1">MANDWPFQKLTVKSLLLSRLQSAIDLSEGGRVYLTCLQPDGRRANPPLQAIENGARYQIDRTNLPETALKLDEIPLNRSKDSLGVVYISAIGLKLAKIWQQTPQVIATKLLETLQPLCNGDFTIGVALSGIIQFELTDRALALWLQHLAQTALPVPQSRILSPVVSVDRLFPIQYSHARCCSLLRMANRDRIIAIGNPNTATAPQIWSLTTPNPIPWLDEEKLRLVHPAEYNLISQLLTVLDNLAPVLEQYNPRKPINYLKLADSLSEAFQTFYSQCRIWGEVKIENPKLAQARLGLILATQSLLRFILEELLNAVAPLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5U2</accession>
    <name>A0A2G4F5U2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57126">
        <property type="protein sequence ID" value="PHX57126"/>
        <property type="gene ID" value="CP500_001630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="8030" checksum="0A60C351F5CC4539" modified="2018-01-31" version="1">MIVDFSLLTVWIFEQHRNSVGWVEALRNPTLILEELGFAKPQPNFAKPNTDFRRVGFRKASTQLCETQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Z3</accession>
    <name>A0A2G4F5Z3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56907">
        <property type="protein sequence ID" value="PHX56907"/>
        <property type="gene ID" value="CP500_002705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="11133" checksum="CCAFCD25E679C699" modified="2018-01-31" version="1">MSNREGFTGGFLAGAAVGGLVGAVLGVVLSRRAAEAFLADPSEAKPIKQSKGKGSQLEDERIEVARLSLEDKIAQLNQAIDDVRLQLGDVNGNAQVHSSQSSLAEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F683</accession>
    <name>A0A2G4F683_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57282">
        <property type="protein sequence ID" value="PHX57282"/>
        <property type="gene ID" value="CP500_001185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="98" mass="11646" checksum="9D8B3937045BA9B3" modified="2018-01-31" version="1">MSNSNENTDENLNFYSVVLSFDAQEFFEEASASLQRKLDRCFEMLKTDPRNHPNIKQLKGDLAGYYRYRVGDYRVVYDIDDEQKRVVVTIIAHRREVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F684</accession>
    <name>A0A2G4F684_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56997">
        <property type="protein sequence ID" value="PHX56997"/>
        <property type="gene ID" value="CP500_002615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045397">
        <property type="entry name" value="DUF6516"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20126">
        <property type="entry name" value="DUF6516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="15268" checksum="C3406D35324FDCE5" modified="2018-01-31" version="1">MLPNILSDYLDRVEQAIQQCSNVYVERYEEEILTSKRANLRIRLRFNQTYLLEINEAIVVADNQLEFLDYRYHFQNEQNQLIFRYDSTPHFPNLPNFPYHKHLPDDVIASDKPEITQVLREAIEVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F690</accession>
    <name>A0A2G4F690_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome d ubiquinol oxidase subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cydB</name>
        <name evidence="8" type="ORF">CP500_001110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57268">
        <property type="protein sequence ID" value="PHX57268"/>
        <property type="gene ID" value="CP500_001110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="337" mass="37487" checksum="86511EFCF2AF69F0" modified="2018-01-31" version="1">MQALEHFLPQVWFVILALFLLLYVMLDGFDLGVGILSLTASDDERRGILMTSLGNVWDANETWLVLMGGALFGAFPLAYGTILTALYIPIMMMLFGLIFRAVAFEFREHSNRKLFWNYAFGAGSFLAALAQGFALGAVLEGIAVDATGHFVGTTWDWLDWRSILVALTLVQGYVLIGSTYLIMKTQGELQTTHYRTAKIAAVTTLIGAILITIATPIFYESARSRLFEKPLVYVFAAIPLLGVLLIGLLLRSLDRQEERTPFVWTILIFLLTFIGLGLIVFPYIIPSQVTIYQAAASPSALVFMIVFIGFLIPIMIFYNIYNYVVFRGKVAGGHYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6E2</accession>
    <name>A0A2G4F6E2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57057">
        <property type="protein sequence ID" value="PHX57057"/>
        <property type="gene ID" value="CP500_001880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="83" mass="9810" checksum="B43F81B012686F24" modified="2018-01-31" version="1">MNLWYINTGDRVDNPAAQKRDQLIHVCFLPIQMRDLEARKVEDFGDGMREVAIRRCQKQQNLIFAKFQNILSGYLLLFRVLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6H0</accession>
    <name>A0A2G4F6H0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Antitoxin VapB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57315">
        <property type="protein sequence ID" value="PHX57315"/>
        <property type="gene ID" value="CP500_000600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019239">
        <property type="entry name" value="VapB_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09957">
        <property type="entry name" value="VapB_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="12911" checksum="0B5AA0AD40972E06" modified="2018-01-31" version="1">MKTTIEIDNSLITNALQATGLTAQQEVVELALNLLIQMKNQQNLRALRGKLAWDGDLDRMRTDDDSDREQSFFEVAGIWEEKNITLDDIRKDAWGKDTFYVASQKNGITECFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6J4</accession>
    <name>A0A2G4F6J4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57376">
        <property type="protein sequence ID" value="PHX57376"/>
        <property type="gene ID" value="CP500_000070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="187"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="395" mass="44751" checksum="DA8555B302A4109E" modified="2018-01-31" version="1">MRLVIVQYAGDYREAYQRLANGGSENYYAQKYSVDAVTEMRKRVESVAVIVCMTPEPYNQVLENGVRAIGAGFNQQLNVKELIELIAHENPTHLVIRTPVREVFNWAIKNKVRTIAVFAESVFTTTWKDKLRSYLLARLLNNKQIEWVGTYGLTSSLLFQNIGVKPNKTIPWDFLIDSDPGSLPPKELPPNVKSVKLFYAGLLIQSKGVGDILEAVAKLKDQNISVHLKMAGKGEEEFFAERVEQLQIKDSVEFLGIVPTQTVEPLMREADLVLVTSKHEYPEGFPLTIHHALRTRTPIVASDHPMFTTHLKHGINSMIFEAGNSLALAECIEKLVTDSQLYHNISVASHSTWHQLRLPVKWAQLIDRWLDDSPESKQWLFEQRLASGAYNSKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6P9</accession>
    <name>A0A2G4F6P9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="8">Holo-ACP synthase</shortName>
            <ecNumber evidence="8">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">acpS</name>
        <name evidence="11" type="ORF">CP500_000380</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57428">
        <property type="protein sequence ID" value="PHX57428"/>
        <property type="gene ID" value="CP500_000380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="10">
        <location>
            <begin position="5"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX57428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="165" mass="17904" checksum="4EB836ECD68EA311" modified="2018-01-31" version="1">MNIYLGTDIVYIPRIQAALDRFGDRFLEKIYTPAEQKDCGQINSQETSIKGKMDRVSCNQLAGRWAAKEAVVKALGTGWRGLRYKDVEVERSDSGAPKVRLHGTAAELASAWGNCQWQLSLSHDGDYCTATAVALCSPHSTAPVGSNSDVTPFSGTGKMPVPQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F704</accession>
    <name>A0A2G4F704_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DegT/DnrJ/EryC1/StrS family aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57377">
        <property type="protein sequence ID" value="PHX57377"/>
        <property type="gene ID" value="CP500_000075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="401" mass="44406" checksum="405AF1C76312BCBA" modified="2018-01-31" version="1">MNNPIRPKDRFLVFGSPAIEDAEIQEVVSTMKTGWLGTGPKVMRFENEFKAYKGSDYAIAVNSCTAGLHLTILAASLKPGDEVITTPMTFCATVNAIIHSGATPILADIDPLTMNIDPAKVEAKITSKTKAILPVHFAGRPCDMDALCEIADRHNLKLIEDCAHAIETEYKGRKAGTFGDFGCFSFYVTKNITTGEGGIILSRKQEDADRLKILALHGMSKDAWKRFGDSGYKHYQVVEVGFKYNMMDLQAAIGIHQMERVAPYWKRREQIWQRYNEAFADLPITVPADPEPETIHGYHLYTILVDEAKTGISRDAFLGAMTAENIGIGVHYQSLPEHPVYQERFGWQPEDYPNAMRIGRHTVSLPISAKLTDADVEDVIAGVKKCLANGKTKNRVLATVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUB9</accession>
    <name>A0A2G4EUB9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dnaA</name>
        <name evidence="13" type="ORF">CP500_023095</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the DnaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000264">
        <property type="protein sequence ID" value="PHX53143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53143">
        <property type="protein sequence ID" value="PHX53143"/>
        <property type="gene ID" value="CP500_023095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="147"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="12">
        <location>
            <begin position="356"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="155"/>
            <end position="162"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX53143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="453" mass="51014" checksum="FDB072BF212E9B9F" modified="2018-01-31" version="1">MSLESLWNQILERLQVQLSRPSFETWIKTARAEQLENNCLIVSAPNPFARNWLQKYYVKIIADAVYEILGYPVEIYLTITGGDETASNGDQGLIWPSPIADVESHSLHPPKPANLNPKYVFSRFVVGSNNRMAHAASLAVAESPGREFNPLFLCGGVGLGKTHLMQAIGHYRLEIDPNAKIFYVSTEKFTNDLIAAIRKDSMQTFRDHYRAADVLLVDDIQFIEGKEYTQEEFFHTFNTLHEAGNQVVLASDRPPQQIPRLQERLCSRFSMGLIADIQLPDLETRMAILQKKSEYENIRLPRDVIEYIASSYTSNVRELEGALIRAVAYLSITGLPMTVENISPVLNPQTETVKATPDAVIAVVAEAFDVSVEDLKSSSRKREISFARQIGMYLIRQHTDLSLPKVGEVFGGKDHTTVLYSCDKIAQLRNTDPNLSQTLRQLSDRINLISRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUF2</accession>
    <name>A0A2G4EUF2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mechanosensitive ion channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_023035</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000260">
        <property type="protein sequence ID" value="PHX53154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53154">
        <property type="protein sequence ID" value="PHX53154"/>
        <property type="gene ID" value="CP500_023035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013673382" evidence="9">
        <location>
            <begin position="28"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="28"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="135"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="276"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="714" mass="78007" checksum="E235B4332ED4D68D" modified="2018-01-31" version="1">MLPKRVRAIFLIAVVSCFALWGMPARSQPADEATASEEATASPKAEKIEPPPQADPKAAVTTKDPEIPVEELQLLVKPLALDELANEAAAWQLLLKNKVKEISDAEIAIKRQNRSINKQQEVAGSLEEAKKALEESDKALKSAAPDSAEYKEATKKAEEAKEKLKKAQEGLKEATQTKKELKQDDTLNDALKKAEKTGELDQAKQTLEEAKKERDKIAPDSPAYTAATEKIDELDKAIKADEEAEKAQKAIADPESPEYEEATQKIEESTAQVKKAREAISGTTTTGGTGAAEKSAQKLDEATSTLENTTIKTGGETPTAGSSAAANSQANQDKKGQQLEKTSDKLEANAKDESVLKNQLVVNATNLQSGRTAVVDRFNVILEELDRKGGESKYYRKYIEAITKAEIDVKDTEGLGVRLLSWLKSDEGGLRWVSNIGKFVGIVLASAIVSQIVGFVISKLLKLSNTSKLMRQFTVVVINRGGIVVGVLLALTALEVSLAPVLTVLGGASFIFAFALQSNLGNFASGLMIMVYKPFDVGDEVKIGSLWGWVDSISLANTKIKGFGGQMFTVPNNAVWSDTIENLTTSDIRKVKFSFRISFDQDVTNIEKVLVDIFKSHPQILEEPAPSTFVFDLEDEYINLIASGWAKTDEFWKVSADILRTIQTRFEQEGIKLGAPPQDIRILPESDENNSLTLDREFTEKQLLHPETANPTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUR2</accession>
    <name>A0A2G4EUR2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2207 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000226">
        <property type="protein sequence ID" value="PHX53271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53271">
        <property type="protein sequence ID" value="PHX53271"/>
        <property type="gene ID" value="CP500_022415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018702">
        <property type="entry name" value="DUF2207_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09972">
        <property type="entry name" value="DUF2207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013606032" evidence="2">
        <location>
            <begin position="28"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="343" mass="38454" checksum="EF7AF34C54B69FD7" modified="2018-01-31" version="1" fragment="single">MNKRLLKKIVFSLMASLSLLLVTVTHAAAQQLPFYWDNINVIIDVQTNGDMLVTETQKYVFTADYNTERYRYIPLDKVDEIKDVTVAENNQIIPSSTGIENNQLWIRWQHQLKAPESHTFVIKYRVRGGLQLDGENTLVYWKAIAAGRKAPINAGKVTVKLPEALSGKVLSFMNFGTAAVRRQVDPKTFEFVASQAIQPEQELEVQIAFPQAILNIPQPGWQQGGKQSQSASGETTISVDDIMEEGSFMERILWFFTFLPLFSIFLTLTIILPIRLIIGWINDRRCPECKQLKIKRTYKVLIRATTSSSGKQAVTKHCGNCSYHKEYEAVIPVIGGDGGGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVL6</accession>
    <name>A0A2G4EVL6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribonuclease J</fullName>
            <shortName evidence="9">RNase J</shortName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rnj</name>
        <name evidence="13" type="ORF">CP500_021160</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, may be a subunit of the RNA degradosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000187">
        <property type="protein sequence ID" value="PHX53506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53506">
        <property type="protein sequence ID" value="PHX53506"/>
        <property type="gene ID" value="CP500_021160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01491">
        <property type="entry name" value="RNase_J_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004613">
        <property type="entry name" value="RNase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030854">
        <property type="entry name" value="RNase_J_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041636">
        <property type="entry name" value="RNase_J_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001587">
        <property type="entry name" value="RNase_J_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17770">
        <property type="entry name" value="RNase_J_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004803">
        <property type="entry name" value="RnjA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00649">
        <property type="entry name" value="MG423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01292">
        <property type="entry name" value="UPF0036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="12">
        <location>
            <begin position="22"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 10">
        <location>
            <begin position="368"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="589"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR004803-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX53506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="626" mass="68277" checksum="48AD839D8360594C" modified="2018-01-31" version="1">MIKNTTAQVLKVIPLGGLHEIGKNTCVFEYGDEIILLDAGLAFPTDGMHGVNIVLPDMTYLRENTHKIKGMIVTHGHEDHIGGIPYHLKQFEIPVIYGPRLAMALLAGKLEEAGVSHRTELRTVRPRDTVRIGKHFLVEYIRNTHSMADSFTVAIHTPVGIIIHTGDFKIDHTPVDGEHFDLQKLAEYGERGVLCLISDSTNSEVPGFTASERSVAPNLDRIIAQATGRVMLTTFASSVHRLQIVLELAKKNNRYVGVVGRSMLNVIAHCRNLGYIKCEDSIFKPLKEIRNLPDDKVLILTTGSQGEPMAAMTRIANGEHHEVKIKKGDTVIFSANPIPGNTISVVNTIDKLMILGANVVYGRDKGIHVSGHGCQEDQKLMINMTRPKFFLPVHGEHRMLVQHSKTAQSMGIPASNMVIIDNGDVVELTENSMRVGGKVPSGIELVDSSRSGVVKANVLKERQQLAGDGAVTVAAALNWEGKLVAKPEVHLKGVVTSADRAEVIGLINQTIETVLSDRWSEFVLPATAADPQVNVDWVGVQTQIEKAIGRVLRRQLQSNPMLVFLMQIPEEAVRSEVVQKTQLSIEAPKLASSSPSSVPAPVPAPVNKVTGRRRSRTAAQVASVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVS2</accession>
    <name>A0A2G4EVS2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1830 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000171">
        <property type="protein sequence ID" value="PHX53619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53619">
        <property type="protein sequence ID" value="PHX53619"/>
        <property type="gene ID" value="CP500_020500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014964">
        <property type="entry name" value="DUF1830"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08865">
        <property type="entry name" value="DUF1830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="14181" checksum="4CB2B17E5DD30622" modified="2018-01-31" version="1">MAQILDPLPSDADSKILCCYVNATSQIQIARITNISSWYFERVVFPGQRLVFEAITAALLEIHTGMMASAILSDTIPCDRLQINEGPYSAINPTRSRPETKSDRTSTTARPKSRDISEPLTLPALTAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVV1</accession>
    <name>A0A2G4EVV1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53576">
        <property type="protein sequence ID" value="PHX53576"/>
        <property type="gene ID" value="CP500_020760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="13770" checksum="A6894D6D1C934DED" modified="2018-01-31" version="1">MILVIINHLKHLMPRRSRARLHTIIHAAATEATAVGFATAQIPGDRFVIGAIQVNMTIELAAEFGATLDTAAAMSVITTGVSAFIGVETFNAIIKYAPGVGNVANMVTAASITETLGWAIVEYYENRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVW3</accession>
    <name>A0A2G4EVW3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53590">
        <property type="protein sequence ID" value="PHX53590"/>
        <property type="gene ID" value="CP500_020675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="27"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="388" mass="43848" checksum="6712F3CBCC89D39B" modified="2018-01-31" version="1">MSQVFDRLQISGYRALKLVNLSQLGQVNIFVGDNNAGKTSILEAVSILCNPLDPFQWLEVSQRRLYLGRSQLMTLRPNIEALKWIFSQKMTASNDEFYQAEILIEVNGTAPIHELRAKLGEIYGSGLEKNNQNRFEEDISSAEEDVSSSEIDSVRAGLELEIVLNLVPGKISSGQLSLFPSEPKSEIFQFWENERFVQRRRNKPIVKNATIFPSYSSSEPILEHLSRIILQQEDGKNELLELMQSFDDNILDIQILSPTATPTIYIKHKELGLTPLYVFGDGLKRTLIIALTLLTTANGVLLIDEIETSIHVSALGSVFSWLIETCRRREIQLFVTTHSLEAIDAMLQPEIATEDVVAFRLNHNGQAPQRFSGNLLHRLRSERGLDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVZ2</accession>
    <name>A0A2G4EVZ2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="2">2.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">5'-phosphoribosylglycinamide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">GAR transformylase</fullName>
            <shortName evidence="2">GART</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">purN</name>
        <name evidence="4" type="ORF">CP500_020320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(6S)-10-formyltetrahydrofolate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide</text>
            <dbReference type="Rhea" id="RHEA:15053"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="EC" id="2.1.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GART family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000166">
        <property type="protein sequence ID" value="PHX53658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53658">
        <property type="protein sequence ID" value="PHX53658"/>
        <property type="gene ID" value="CP500_020320"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="3">
        <location>
            <begin position="33"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="5'-phosphoribosylglycinamide binding" evidence="2">
        <location>
            <begin position="42"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="10-formyltetrahydrofolate binding" evidence="2">
        <location>
            <begin position="120"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="site" description="Raises pKa of active site His" evidence="2">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="227" mass="24761" checksum="28EA215E194822D0" modified="2018-01-31" version="1">MITANTNSKDCLIVPAIPHAQIAKNADINEPLKLGILASGSGSNFEVIAQAIQNQQLNAQIQVLIYNNPGAKAAARAEKYGIPSIFLNHRDYKKREALDTQIVKTFQEYDVKWVIMAGWMRIVTKVLLDAFPDQVINIHPSLLPSFPGISAVEQALAAKVKITGCTVHIAHLEVDSGPILIQAAVPILPDDTPETLHARIQVQEHKIMVGAIALIAHRSTVTNTFNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW13</accession>
    <name>A0A2G4EW13_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Single-stranded DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_019855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000158">
        <property type="protein sequence ID" value="PHX53742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53742">
        <property type="protein sequence ID" value="PHX53742"/>
        <property type="gene ID" value="CP500_019855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="20242" checksum="50623939F403C788" modified="2018-01-31" version="1">MNSFILMAEIIQQPQLRYTPDNQLQIAEMLVQFPGSRPEDPPEHLKVIGWGNLAVEIHEKYREGDRVIIEGRLGMNTIERDGIKEKRAEMTAQKISSLGANAMNSAPATNRTAPESAPIRSSAPSTVPSNVVPMSSRNRSSSNAPGGSSNTSSSDWNSPQSPSSDSDRQSNSSSESDNPDYDPIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWK8</accession>
    <name>A0A2G4EWK8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000178">
        <property type="protein sequence ID" value="PHX53557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53557">
        <property type="protein sequence ID" value="PHX53557"/>
        <property type="gene ID" value="CP500_020870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="78"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="314"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="506" mass="58007" checksum="4ED65B4AB32D862A" modified="2018-01-31" version="1">MSGEKSRYVSVEEQELRRLREQESRLRSVQQDLPERLNAVRQQAQQEFQQRLAPLEQRARQQEQETQNLKSNIASLEQDTQKRLQQQRQDFKTAVREAESRQQQALQQETSRLESAQRQGFEQQRGEYLRITAQQRQEYTGLIDRQDRKFTQLIAEEQQARERGQKVLQVQIDRVVDNLEQETQRKAKIAEDLLSDVAVIWEQINRDYQHQRFAPGKLADLHRGLEMARSNIQAGLTEAAIATTQQTYLDLADLRIQLEQKEQEWLLLYNAAWEDLKSLIVEVQANKECEIEMGEGDEAQKFKLEVDYWVNGRLSEYEQQLNQLESQLKAGESKLTTEQVQELGEQIIALQPILGEIVEQAKLTILGSQLRVEIADKVVGALESLGYTLVDSESDAVYEGNDQRNAFVVKVKNIAGDEVVTVISPEKEFGANSVSINSFSQTLVDETATRQNAKAIFDALEEEGVEGDGEPVCNQKAQQEYQNLEEVKRRQVAPPPSPSVSSRQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWM4</accession>
    <name>A0A2G4EWM4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000147">
        <property type="protein sequence ID" value="PHX53866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53866">
        <property type="protein sequence ID" value="PHX53866"/>
        <property type="gene ID" value="CP500_019205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Amino_oxidase" evidence="2">
        <location>
            <begin position="14"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="483" mass="54923" checksum="8243E39EC6548F4C" modified="2018-01-31" version="1">MKHYPVAIVGAGPAGLTAAYELVKQGIIPVVLEKGDKVGGIARTETYKGYRFDIGGHRFYTKVAAVQQLWQEVLGNDFIKVPRLSRIYYRGRFFNYPISAFNTLFNLGIFESLLILLSYLKVRIWPLPEETTFEQWVINRFGDRLYKTFFKTYTEKVWGIPCSEIQADWAAQRIKGLSLTTAIINALFGSNDTKTLIKEFDYPALGPGMMWEKFAEAVESKDGKVYLDTKVISFQREGNKITSITAEHNGELVQFSADNFITSMPISALVARLYPQPPEEVLHAARSLKYRDFLIVSLIVDRKDLFPDNWIYIHSPEVKVGRIQNFKNWSAALVPDVSKSCLGMEYFCSVGDEIWEKSDVELVELATRELVGLGLAKTADVEDGVVIRQLKAYPVYDGEYRGHLRVLEGFLKGIENLQTIGRNGMHRYNNQDHSMLTGILAARNILGEKHDLWDVNTERSYYEDFTVDRSKEKKNSGLISQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWM5</accession>
    <name>A0A2G4EWM5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000137">
        <property type="protein sequence ID" value="PHX53945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53945">
        <property type="protein sequence ID" value="PHX53945"/>
        <property type="gene ID" value="CP500_018740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="199"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="405" mass="44251" checksum="0CD31D712C298ADB" modified="2018-01-31" version="1">MISTLPNLTSVDSSQLRLEIRNLQPQLVEWRRRLHQKPELSFEENLTAEFVSQKLQEWGIEHQTGIAKTGIVATIDSGKPGPILAIRADMDALPIQEENEVDYRSQHDGIMHACGHDGHTAIALGTAYYLANHKHSFSGQVKMIFQPAEEGPGGAKPMIEAGVLRNPDVDAIVGLHLWNNLPLGTVGVRSGALMAAVETFDCTILGKGGHGAMPHQTVDAIVVAAQIVNTLQSIVARNIDPIDSAVVTVGKFHAGCTHNVIADTAQIGGTVRYFKPAYQGYFDKRIEQVIAGICQSYGANYKLDYCSYYPPTINDANIAELVRTIAESVVETPAGIVPECQTMGGEDMSFFLQEVPGCYFFLGSANPEKNLAYPHHHPRFDFDETALGMGVEMFVRCVEKFCANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWU9</accession>
    <name>A0A2G4EWU9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin)</fullName>
            <ecNumber evidence="4">1.17.7.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">ispG</name>
        <name evidence="5" type="ORF">CP500_018430</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:26119"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="4">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IspG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.1" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54013">
        <property type="protein sequence ID" value="PHX54013"/>
        <property type="gene ID" value="CP500_018430"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016425">
        <property type="entry name" value="IspG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="PTHR30454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004640">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 4" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="406" mass="44649" checksum="05CEB976BDC7C12B" modified="2018-01-31" version="1">MQTLPNPTKTPNPEPIFDTSIKRRKTRPVKVGSITIGGGYPVVVQSMINEDTLDIDGSVAGIRRLHEIGCEIVRVTVPSMAHAKALAEIKQKLIATYQTVPLVADVHHNGMKIALEVAKHVDKVRINPGLYVFEKPTADRTEYTAAEFAEIGETIRETLEPLVISLRDQGKALRIGVNHGSLAERMLFTYGDTPQGMVESALEFIKICESLDFRNIVISLKASRAPVMVAAYRLMVHRMDELGMDYPLHLGVTEAGDGEYGRIKSTAGLAPLLADGIGDTIRVSLTEAPEKEIPVCYSILQALGLRKTMVEYVACPSCGRTLFNLEDVLHKVREATKHLTGLDIAVMGCIVNGPGEMADADYGYVGKQAGYISLYRGREEIKKVPEDRGVEELINLIKSDDRWVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX16</accession>
    <name>A0A2G4EX16_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4360 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54018">
        <property type="protein sequence ID" value="PHX54018"/>
        <property type="gene ID" value="CP500_018460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="entry name" value="PTHR38847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013606034" evidence="1">
        <location>
            <begin position="23"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="190" mass="20555" checksum="BD499FA633D000C4" modified="2018-01-31" version="1">MKFVKLLLAAAFMSASISPALAQEKVQILGASYGGTGCPDRSASVSVSPDGQELTILFDKFVAQGNVSAEKRKSCNLSIPIKVPQGFQISLYDADYRGYVAPKTSANLRAEYFFAGNRGPVFSRTFNGETNYNVRDSLATVADVWSRCGDSINMRVNASMTANGAGTATVDSFDLAHRGLVYHIKYRTCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXD1</accession>
    <name>A0A2G4EXD1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245734">
        <property type="entry name" value="Tbo703ORF17435P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54193">
        <property type="protein sequence ID" value="PHX54193"/>
        <property type="gene ID" value="CP500_017430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="21006" checksum="F4643C1E0524D03C" modified="2018-01-31" version="1">MMTEKKLEQILARYQNSFTEKVYTEENEEHDILMDVFGISPIIKKENKQYWGRELGMCWQLLVTETCKAYCSSFQPAFKVGSDEPCDLIVDGYAIDTKYRIGSGDSGTLKKFKSYGPLLRTYNYEPVFLILRQDNLPAAITACQVGTWRVYTGDASFNFIQTISGFDLKSFLTKKVGEFPVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXG2</accession>
    <name>A0A2G4EXG2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54219">
        <property type="protein sequence ID" value="PHX54219"/>
        <property type="gene ID" value="CP500_017285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8065" checksum="809FF52FF2285E7E" modified="2018-01-31" version="1">MSLAELIPLVNSLSQPDKLSLFKLLTVQIPKAELQVIFSASEYPVWSPYDATEAANIMMQMIRDDREASTHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXL5</accession>
    <name>A0A2G4EXL5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54261">
        <property type="protein sequence ID" value="PHX54261"/>
        <property type="gene ID" value="CP500_017115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="19340" checksum="1C5F0A1CC92BB7EA" modified="2018-01-31" version="1">MSNIIRFYRLLLPFENLKITTSLTFSQVLQRLDEVVDTPKLFRITLPFGPPPPKPYEGTIYGKTFKISRIISGRNSFLPLIEGEIYPQPFGCHININMSLPKIVLVFMLLWLWTTGSIGIFALFAWLAEPSIGPIFIPLLGMFIFGLLLCIIPFKIEAKIATKFLSTLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXP7</accession>
    <name>A0A2G4EXP7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54220">
        <property type="protein sequence ID" value="PHX54220"/>
        <property type="gene ID" value="CP500_017290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8683" checksum="9A6D283A57C1F049" modified="2018-01-31" version="1">MTELLQQAIAQIQKLPPDRQDAIASRLLAELQDEQKWESRFAATTDDQWDRMAAMVRQEIAAGETTPLSEVFLTHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXS1</accession>
    <name>A0A2G4EXS1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Urease accessory protein UreE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ureE</name>
        <name evidence="7" type="ORF">CP500_016800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UreE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54333">
        <property type="protein sequence ID" value="PHX54333"/>
        <property type="gene ID" value="CP500_016800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065003">
        <property type="term" value="P:protein-containing complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019627">
        <property type="term" value="P:urea metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00571">
        <property type="entry name" value="UreE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00822">
        <property type="entry name" value="UreE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012406">
        <property type="entry name" value="UreE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007864">
        <property type="entry name" value="UreE_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004029">
        <property type="entry name" value="UreE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036118">
        <property type="entry name" value="UreE_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05194">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02814">
        <property type="entry name" value="UreE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036402">
        <property type="entry name" value="Ureas_acces_UreE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00988">
        <property type="entry name" value="UreE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69287">
        <property type="entry name" value="SSF69287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0533">Nickel</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UreE_N" evidence="6">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="145" mass="16176" checksum="F11987616D43FC10" modified="2018-01-31" version="1">MITFTKHLLANPDAVVSFTLPMTADDRTRSRHRFETDTGEVVNLHLPRGTVLRDRDLLQSEDGSCLVLVTAKPESVLTVRASTPLLLMRAAYHLGNRHVALEVTDHYLRFSPDAVLQGMLEKMGLEVIAEIMPFQPETGAYGHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXT9</accession>
    <name>A0A2G4EXT9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53977">
        <property type="protein sequence ID" value="PHX53977"/>
        <property type="gene ID" value="CP500_018550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="193" mass="21839" checksum="53675B5AFA128CB6" modified="2018-01-31" version="1">MTPQTPDSQYFRNCETQAEMELLATIVQTDVAYPWNPAQLESESYLMALEQEFALSDSFSDTDIALKSQVLFSQLEQVWLTTTLQKSLREKFAGFPQNLLASIAQSVQNATVKYQLLADQMVDCVVDILPQWAEEDLQVFARPLAYAMRDVDSEGGELGMVLRKPWEELSEIEQARVSLTVARYAISQLEVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXX2</accession>
    <name>A0A2G4EXX2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54300">
        <property type="protein sequence ID" value="PHX54300"/>
        <property type="gene ID" value="CP500_016835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="198" mass="23087" checksum="E5BC6BED4AC2ADE1" modified="2018-01-31" version="1">MTEMFNPDYTEGKFDFTSETPASEILANYIFTPENMTQPCVGFLLHRSGARFGNWPDLWSLLEQDKELAVISLRRQNLLRRYLSVQLMKNQDLEGNPPAPMHFDKQLLIRDFQKQEAKIAEFDARFSDHPLTTVTYEDLCDRYAETMVRIQSFLNLTPANLQPGTKKRATPPLADVISNYTELKREFADTKWFSFFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXX8</accession>
    <name>A0A2G4EXX8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uppP</name>
        <name evidence="15" type="ORF">CP500_016375</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="NXIB02000104">
        <property type="protein sequence ID" value="PHX54394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54394">
        <property type="protein sequence ID" value="PHX54394"/>
        <property type="gene ID" value="CP500_016375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00753">
        <property type="entry name" value="undec_PP_bacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX54394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="302" mass="32029" checksum="71E25F2F9DDC4AAC" modified="2018-01-31" version="1">MIALLDILAQTPTADVSGPAQINILQAIVLGIVQGLTEFLPISSSAHLKVVPIALGWGDPGVAYTAVIQLGSIVAVLWYFWKDLTTITFGAVDAVVRRDYESQEFRIALGIALGTIPIIFFGLLIKILIPDFDKSPLRSLGAIAIASIVMSLLLAIAEKMGKRDRTYEKLTVQDGILMGLAQAIALIPGCSRSGSTLTAGLFIGLERPAAARFSFLLGIPAITLAGLVELKGALGEGMGDAGVVALIVGTISAFVFSYLSIAWLMKFLQTQNTWIFVWYRLAFGVAILTALAGGVLKNPSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXY4</accession>
    <name>A0A2G4EXY4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Acyl carrier protein</fullName>
            <shortName evidence="7">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">acpP</name>
        <name evidence="11" type="ORF">CP500_016620</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 9">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54338">
        <property type="protein sequence ID" value="PHX54338"/>
        <property type="gene ID" value="CP500_016620"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 7 8" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7 8">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="84" mass="9113" checksum="0ACF7EB62F885656" modified="2018-01-31" version="1">MSQDEIFDKVKKIVAEQLEVDASEVKPESNFANDLGADSLDTVELVMALEEEFDIEIPDEAAEGITTVQASVDFIKEALAAPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY18</accession>
    <name>A0A2G4EY18_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4276 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54350">
        <property type="protein sequence ID" value="PHX54350"/>
        <property type="gene ID" value="CP500_016635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025455">
        <property type="entry name" value="DUF4276"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14103">
        <property type="entry name" value="DUF4276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="27297" checksum="4667E8AB0A280079" modified="2018-01-31" version="1">MVVWVYSGGGEAEVRGFFPFLEKTFPGCIFIRKTPARQKPGPKANKAGSYGRTGKSLIEQIKQKLPLALKAEPNKCDLILVFDDLDCRDSQIQKTKILTELSKILECAALNKFVGFAAPEIEAWIIADWNNSIAKNYDFRGRHERMRWWLSQDKNVRFDIPESFSEYDSDKDSCREKLSDVLIASTIVEHESNLDKARFSKGLHTPLLLMAIDPNEVQKKCPLFRELYNYFNDFCCCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY29</accession>
    <name>A0A2G4EY29_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aromatic ring-hydroxylating dioxygenase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016530</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54360">
        <property type="protein sequence ID" value="PHX54360"/>
        <property type="gene ID" value="CP500_016530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="28"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="356" mass="41491" checksum="6D2F353A49A04932" modified="2018-01-31" version="1">MQNNTLKSPFQNTDKTHIRQLGINLNQWYTVARSTEVQTQPLPVVIWHKAIVLFRDSAGKINALEDRCPHRQVKLSHGKIKGDLIECAYHGWRLNARGECAEVDYLADNQKLPNCKISSFPVKEKDGFIWIFPGDETKAEQIDLLSLPEWEHLNYIATVAVIDCQANHSFLIENLMDMYHGHLHDDWQAWANPVLNTLDEDEHQVTALYQAESYYKIDKIWSISQLFFKSLRQLHPEPLKVSYVYPHWVSTLGNDFKIYCLVCPVSETATRAYLIHFTSLNAFWRLHKLPVWFRKFIKDSCFGAAQKLLDGLVRQDVLMIEEEQQAFLQSSERKSYELNRALASVQRLMRSQAEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY83</accession>
    <name>A0A2G4EY83_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-histidine N(Alpha)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">egtD</name>
        <name evidence="4" type="ORF">CP500_015765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54493">
        <property type="protein sequence ID" value="PHX54493"/>
        <property type="gene ID" value="CP500_015765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035094">
        <property type="entry name" value="EgtD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03438">
        <property type="entry name" value="egtD_ergothio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_33" evidence="3">
        <location>
            <begin position="40"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="343" mass="37985" checksum="15CB9EA8114D78D8" modified="2018-01-31" version="1">MKSSRLSEKTNSASTKANRLHLERLVNAAAPTSAEINAGSDVVSGLTQTPKSLPPKYFYDDRGSNLFELICQLPEYYVTRTEAAILEGCAGAIANLTGPCEIVELGSGSSTKTRILLDAYSQREYPLHYLPIDISPTILESSADQLLADYPSLQIHGLVSTYELALAKIAPSPLPSRMICFLGSTLGNLGPQECDVFFSQIVGALQPGEYFLLGIDLDKSKDILEPAYDDNQGVTAAFNLNMLRHLNRKYEGNFDLTQFEHLAFYNQAECQIEMHLKSQKAQTVNLRALDLTVEFAAGETIRSEISRKFKLHTVQEELASRGLKPVEVWTDPNQWFGLILCQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYB4</accession>
    <name>A0A2G4EYB4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Adenylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_015615</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000094">
        <property type="protein sequence ID" value="PHX54522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54522">
        <property type="protein sequence ID" value="PHX54522"/>
        <property type="gene ID" value="CP500_015615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="10"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="546"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="815"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="7">
        <location>
            <begin position="981"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1167" mass="130083" checksum="846FE474DBFB3F96" modified="2018-01-31" version="1">MNSPANPKLKILIVDDEPDNLDLLYRTFYREYKVLRAESGPAALEILAREGEVAVIISDQRMPKMSGTEFLRLTAAQYPDVIRIILTGYTDVEDLVEAINAGKVFKYVTKPWDAEELRALVSQAVDTHNLLKARTNELRRALQQESLLYAVTNTIRSALNYQQMLQRIVETVGQMFEVGCCLLRPFQDGRVADEWFVYELLKTQELSSSDATVMPLDADPAGLSADLLPLLVWETREVEVIQDAQTDDRILHEANDQRRLAYQAANIRSSLIVPLFYQTELMAVLALHSFEQPRQWEEHEINLVTTVADQAALALSQARAYEQVRALAKREALVNTITTAIRSSLDPQNIFAAITEQLGQALQADGCVLSLWTEDDEYVQCVGLYDSEREFVAVEEDFSSPNVLANPDSVTKFDRPWASPNASLPQSLVPIRGNPVLQIIMMSKEPVAISDLNERPDMNVTELQLRSAARALLVVPLLSDGKIIGSISLRQNSHTRRWLASDIDLAQIVAAQAALAVQQSRLYQTTRQQAERLLEADRLKTEFFQNISHEFRTPLTLTIGPLESVCSRKEDLPYEQAAIALRNSRRLLRLVNQLLDLQRLDARRMQPSFRPCDLVGFCYSTAESFRPYCDKKHLNLITELQECPLLYLDIERFDKVIYNLLSNAVKFTPEGGNITLKIEQAGSHCLLQIKDTGIGIRTEQIPYLFERFRQAEGSANRSYEGSGLGLALVKELVELHGGQISVESVYGEGSTFTVWLHLGSTHLPPEQVLEIPTEFNSSKAVVELADVEGDLSDAEIGSESFEAIEPVNSETAVGTVLVVDDNPDLRFYVSGILRDSGFTVLLARNGEEGFAVAKNRLPDLIVTDLMMPLVSGLDLIRMLREDQELKGTPVILLTAKADEDTRIEGVERGADAYLSKPFNDRELLAEVRNLVALKENERRVQQLNNYLTESVLRRFLPPAMVKAAAAGELALDLRPEPRLITILFSDIVGFTQMANTLRSRRVAELLNEYLAAMTKAIFDSGGTVDKFVGDAVMALFGAPEELSPNEQVRRAVAAAKQMLLALKELNQSWIKQGIVGENGVAPVRFRCGIHQGTAVVGMFGGVERSDYTAIGPSVNIAARLQEATEPNTVLISAAVADYVEEDRIIKYKSLQFKGIDETVLTFLLNCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYF1</accession>
    <name>A0A2G4EYF1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54541">
        <property type="protein sequence ID" value="PHX54541"/>
        <property type="gene ID" value="CP500_015585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="504" mass="57517" checksum="039540EA660D8E09" modified="2018-01-31" version="1">MIKSKRDRGRILTATGLKKLNEAIQEWSDRYNIRGTLTEIEAECGVGSDTVSKIRQGREGADLSKIRRLFAAFDLTLTNIDHRSAKLDDAEDTDEPRDLLPTEETADRSRSVKIFISYQSTEPDRELGKQLETALSAIGHTVFTEDLTPNQVLEITNQNVPLAASEPELPGGQLDVASQFYIERHPIEERCYQTILQPSALIRIKAPRQMGKTSLMARILHHASCQDYRTVPLTFQLVDKTVFANLDKFLKWFCAYVGRELNIPNQLDDYWDKIFGSKVNCKDYFEKHLLPQIDTPLVLGLDEIDRVFQYPDIAEDFLGLLRAWHEESKRRDIWKKLRLIIVHSTEVYIPMNINQSPFNVGLPVDLPEFNAVQIQDLAARHNLNWSNQEVDKLMAIVGGHPYLVRVALYHISQSELTLNELKESAIADAGIYSDHLRRQLWNLEEYPELAAGMREIAAADSPVQLKAIQAFKLDSLGLVKLQGNECVPRCDLYRQYFKINLGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYM9</accession>
    <name>A0A2G4EYM9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000090">
        <property type="protein sequence ID" value="PHX54580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54580">
        <property type="protein sequence ID" value="PHX54580"/>
        <property type="gene ID" value="CP500_015315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="28"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="179" mass="20278" checksum="69BE966538108154" modified="2018-01-31" version="1">MLTSTDFSGLLNQRFFQNLLPVPATNVLKLGQMTPDFELPDVNNGKLVRLSNYRGDRPVVLAFTRIFTEKQYCPFCFPHIKALNENWEKFADRNIELLMVTSTDDRQSQIVVRDLGLKMPLLSDPSCEVFRGYETGQALGAPLPAQFVLDADGKLLFKHLFSFIDHNASVETLLKSLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYY2</accession>
    <name>A0A2G4EYY2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dnaG</name>
        <name evidence="16" type="ORF">CP500_016260</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13 14">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="domain">
        <text evidence="12">Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54397">
        <property type="protein sequence ID" value="PHX54397"/>
        <property type="gene ID" value="CP500_016260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="15">
        <location>
            <begin position="266"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CHC2-type" evidence="12 14">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002811-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX54397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="675" mass="77777" checksum="67241E9255E57622" modified="2018-01-31" version="1">MQVPRLHPETIEEVKQRADIVDVISGRVVLRKRGKEFVGLCPFHDEKSPSFTVNQAKQMYYCFGCGAGGNAFKFLMELEKRSFSEVVLDLAKTYQVQVKTVEPEHRQELQRQISLREQLYEISALTAKFYEHALRQTQGQETLAYLKSNRQLSEETIQQFQLGYAPQGWEALYSYLVEQKHYPAQLVEQAGLIVPRKSGGSGYYDRFRNRVMIPIRDTQGRVIGFGGRALGDEQPKYLNSPETELFDKGKTLFALDTAKIAISKADRAVVVEGYFDAIALQAAGIGNAVASLGTALSLNQVRQLLRYTDSKQIILNFDADKAGTQAAERAIGEIEKLAYQGEVQLRVLNIPDGKDADEFLKTYSPEQYRELLKTAPLWLDWQLQQMLINQDLKQADTYQQITKKIIKLLTNITDDNQLTHYLQKCAEILSKGDYRLTKMLADNLLNQVINDWGKRLSQDESLTMPLLIRKKLKPNKQYNKQTTTSEKKHSKESFAAVARTLLEEAEGQLLQIYLHCPEYRQDVRESIEAREVQFSLSHHRFLWHQILNAEILHKISLQIAPSELILRLQDSLIEYPNQLNQISHLFHLNELSEKNVYRAPLVIRSALACIEQIISMKRRRIALNMWENTDAASNCEEALEYHQQFLAEQEWIRELERLRQVNFYDLISVPWSGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ31</accession>
    <name>A0A2G4EZ31_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rho termination protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54761">
        <property type="protein sequence ID" value="PHX54761"/>
        <property type="gene ID" value="CP500_014355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032585">
        <property type="entry name" value="DUF4912"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16258">
        <property type="entry name" value="DUF4912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho_N" evidence="1">
        <location>
            <begin position="7"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="445" mass="49215" checksum="39FC2FBD6EDFA74E" modified="2018-01-31" version="1">MVKERPPLEEMTLRQLRRVASECGVSRYSRMRKSQLLASIQEIQRTKFSYTPSRKLEAQETVEAAKFELGQEDQTGGSLSSVDEGLADLPNGYGESRVVLMPRDPEWAYTYWDISNDHKQELRRQGGQQLALRIYDVTDVNLEIQSPHSIQEYPCDELAREWYVPIPVSDRDYAIDIGYRCADGRWLILARSAEVRVPPVYPSDWIEDQFITLDWEEDLRGQTFAELVPPAKKIAESATAAATYSNGNAIYEQIFGMAESAEALRVAGSVFGSMQHVPGSIQQVGIHEQAVSSYVFPSGVGMWAAPAMSGLTMSGVGMSGLTTSGVGMSGLTMSGVGMSGVGMSGVGFATPMRPRQFWLVADAELIVYGATEPDATVYIGGQPIKLNADGTFRFQMSFQNGLIDYPIFAVAADGEQNRAIHMKFERETPERRTNTKEDAVVEWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZC2</accession>
    <name>A0A2G4EZC2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54865">
        <property type="protein sequence ID" value="PHX54865"/>
        <property type="gene ID" value="CP500_013875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="6921" checksum="AD95314A5ECA70DB" modified="2018-01-31" version="1">MLKKSVVFTEKAKEKNLKKELLTGLVSSNAFTLAIVALIHFNVLDTPDLFSSKQSIDLFGALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZC6</accession>
    <name>A0A2G4EZC6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54871">
        <property type="protein sequence ID" value="PHX54871"/>
        <property type="gene ID" value="CP500_013620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="12"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="661" mass="72420" checksum="B12F649BB54FA115" modified="2018-01-31" version="1">MIAPDTILRKRYQIIKFLAGGGFGDTYLAKDLDLPGKPHCVVKHLKPKDNRPVVLQLARKLFDIEAQVLYNLGKQCPQIPTLFAHIEENGEFYLVQEFIDGHDLNTEIVPGKKLSESTVITLLKNILEVLTVPHEHQPNAVIHRDIKPANLMRRQDGKIVLIDFGAVRQINQLIVNVNGDVTTTIAIGTPGYMPSEQAKGKPKLCSDVYAVGMIGIQALTGIPPQQLQEDPRTGEVIWRNLVPRIDSRFADVLDKMVRDHFSQRYQNAGEALQALLSLSTNPSGSKVKTIPVIPQHTWPLPTNTTRRGLLQLVGFAGGGFALAVLSQSLLNNKSSSSSPSPSPPSDNEPPSPESSAQKSSSEPIAESPSPEASPKPSPETPAPKASSNSLKTFDFETVTVNSTGQIANRSQGQARVFTDNLGDGITIDMIAIPGGSFVMGSPSTEAGRYDNEGPQRTVTVAPFFMGKYEVTQEQYQAVMGNNPSNFKGAKRPVEQVTWDEAVEFCRKLTQKTGKSYRLPSEAEWEYACRAGTTTPFYFGDTITPDLVNYNGNNPYGAAPKGLYRQQTTDVGSFPPNPFGLYDMHGNVWEWCSDKGHGNYSGAPTDGSSWETGTDNNRVQRGGSWNNHAVHCRGAYRNYFSADFRWGHWGFRVAVASVSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZF6</accession>
    <name>A0A2G4EZF6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54889">
        <property type="protein sequence ID" value="PHX54889"/>
        <property type="gene ID" value="CP500_013720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="149" mass="16727" checksum="A451AFD9F241A39A" modified="2018-01-31" version="1">MIKKEVLAEDESSQLVDEISELKEILREVSKKLTRIEGKVKRGGFSATPKVSESTVSQPDKTNEKPAGLSAEQVIQIYEQLRLKAKNGNEEEVRKKLLSMTATDLSLICLELGMPPTAKNPSRKKMIEIILGRIKQSLMLSRHIDRQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZR4</accession>
    <name>A0A2G4EZR4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 3</fullName>
            <shortName evidence="5">RF-3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">prfC</name>
        <name evidence="7" type="ORF">CP500_013040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55002">
        <property type="protein sequence ID" value="PHX55002"/>
        <property type="gene ID" value="CP500_013040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006449">
        <property type="term" value="P:regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04169">
        <property type="entry name" value="RF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00072">
        <property type="entry name" value="Rel_fac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004548">
        <property type="entry name" value="PrfC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032090">
        <property type="entry name" value="RF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038467">
        <property type="entry name" value="RF3_dom_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041732">
        <property type="entry name" value="RF3_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43556">
        <property type="entry name" value="PTHR43556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16658">
        <property type="entry name" value="RF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00503">
        <property type="entry name" value="prfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="14"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="23"/>
            <end position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="91"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="145"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="542" mass="61588" checksum="F3948AC8C6BCD6C9" modified="2018-01-31" version="1">MTTELEIELQTATRCRRNFAIISHPDAGKTTLTEKLLLYGGAIHEAGSVKARRAQRHATSDWMEMEQQRGISITSTVLQFEYKKYHINLLDTPGHQDFSEDTYRTLAAADNAVMLEDAAKGLEPQTRKLFEVCKLRSLPIFTFFNKLDRPSREPLDLLDEIEKELGLQTYPVNWPIGTGDRFKGVFDRRQRQIHLFERTQHGSRAAVDTVMELGDPRLEELLEPDLYSQFKDDLELLDELWDELDLDLVATGKMTPVFFGSAMSNFGVELFLDAFLDYALKPSARKSSAGELPPTYEEFTGFVFKLQANMDSRHRDRVAFIRVCTGKFEKDMNVTHARTGKTVRLSRPQKLFAQDRESIDVAYPGDVIGLNNPGVFAIGDTIYTGQKLEYEGIPCFSPELFAYLRNPNPSKFKQFRKGVSELQEEGAVQIMYSVDESKREPILAAVGQLQFEVVQFRMQSEYNVETTIDMLPYGVARWVDGGWDALAKVGRLFNTVTVKDSWGRPVLLFRNEWNCQQVEGEHPVLKLNAIAPVVSGLEVIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZU0</accession>
    <name>A0A2G4EZU0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55022">
        <property type="protein sequence ID" value="PHX55022"/>
        <property type="gene ID" value="CP500_012975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8164" checksum="4CADC53664292F3E" modified="2018-01-31" version="1">MNDQKEMIHFNLDLSPELNDTLEQMAKKIGGSKTDVLRQAIALMQIVVTAKEQGRKFGIAEENQPLATEILIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZU1</accession>
    <name>A0A2G4EZU1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55015">
        <property type="protein sequence ID" value="PHX55015"/>
        <property type="gene ID" value="CP500_012940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="355" mass="41281" checksum="949F540A853CDBF9" modified="2018-01-31" version="1">MLFGYPIAATAKNWLHECLCEILRSIHASLQAAKTPPTWPEIIPDLYRNRLQKRTGLKDRLKTYQNTVEKLTTAEQEQIIQALNDQNHIALLLSCQLTCDTITDLPEAIHEPVKKLFEFAFELLTKLEIRDHHYKAIYDSVSDHVCPFCGFEYFDAPGAPREALDHYLAESKYPFAASNLRNLVPMGNKCNSRYKIAQDILFRNDGTRRKSFDPYSYNCKGIRLSLENSQPFAGEVTPTGELPRWQIEFSPNTEEVITWDEVFHIQERYKRDVLDAEFKTWLWQFKSWCKSRNIVPSSHQELLDEIDHYANYYEDQGMSDRAFLKAAVFRMLHTHCQNGDRRLISLIEGVIGINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZV3</accession>
    <name>A0A2G4EZV3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">S-formylglutathione hydrolase</fullName>
            <ecNumber evidence="3 7">3.1.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fghA</name>
        <name evidence="8" type="ORF">CP500_012795</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Serine hydrolase involved in the detoxification of formaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + S-formylglutathione = formate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="3.1.2.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the esterase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.12" evidence="3 7"/>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55040">
        <property type="protein sequence ID" value="PHX55040"/>
        <property type="gene ID" value="CP500_012795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018738">
        <property type="term" value="F:S-formylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014186">
        <property type="entry name" value="S-formylglutathione_hydrol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061">
        <property type="entry name" value="PTHR10061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02821">
        <property type="entry name" value="fghA_ester_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0719">Serine esterase</keyword>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR614186-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="291" mass="32252" checksum="F87E58DDF85A452C" modified="2018-01-31" version="1">MSKSLKLHQEYKSFGGKLGYYSHQSSACNSEMKFAVYQPPQAQYQPVPILYFLSGLTCTEENFMAKAGAQQFAAKYGLMLVAPDTSPRNTGIPGADDNWDLGSGAGFYIDATAAPWNAHYQMYSYVVDELPELIAKNFPVIPEKQGIFGHSMGGHGALICALKNGVKRSYPEGNRYLSVSAFAPICAPMHSPWGQKIFSHYLGDNREDWRAWDASELVLQSQYNRPILIDCGTADSYLADGQLLPEVFSEACAKTGLPLTLRMQEGYDHSYYFVASFMEDHIQHHAAILCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F096</accession>
    <name>A0A2G4F096_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_012380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55173">
        <property type="protein sequence ID" value="PHX55173"/>
        <property type="gene ID" value="CP500_012380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="6">
        <location>
            <begin position="12"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="5">
        <location>
            <begin position="442"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="736" mass="80345" checksum="BBEC8FF77790F34A" modified="2018-01-31" version="1">MPIAILVLVEVLIVIALSRLVGLAFRWIKQPQVIGEIVAGIMLGPSLFGLVAPDLAAAVFPAEAVPFLDVLSEIGLIFFMFLIGLELNPKYLKNNLDTAILTSHVSILVPFSLGSLLALLLYPIISNNSVSFTAFALFLGAAMSITAFPVLARIITEHNLQNTKLGTLALTCAAVDDVTAWCLLAVAIAVTRTNSMIGALPTIFEALIYIVFMLTVVRWFLQRLSKHYNRTGRLTQLVLAGIYMGVVASALITEWIGIHLIFGAFLLGAVMPKNAGLTRELAEKTEDFVLIFLLPIFFAYSGLRTEIGLLNSPELWLLCAAVLGVAIIGKYVGTYVAARVCGISNRESSALGWMMNTRGLTELIVLNIGLSLGVISPLLFTMLVIMALVTTFMTSPLLEWTYPKRLIRLDISEFSSDDSELEDSENAKITEKTDEKLLPTYRILVPVANPSTQKGLLQLAVALAQPAAGTGGNDLQSAAVHPLSLIELSKDYAFESTPAEADRIIQDRHLKLGELIESLQPPEARKLVHPIIRVTNDVARETAQIAELDRADLILVGWHRPTFSSNRLGGRVGQILSTAKVDVAIFVDRGRERLNNLLVPYAANIHDDLGLELALRLLVNSEERRLTVLRVATVDGEAAENELSYEFKRVIEQLPVEVQSRIETPIVEAAEPIQAVIAASANADLTIAGTSREWGIERQTLGQYTDELAVQCHSSLLIARCYVKVRSHLASVLPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0D1</accession>
    <name>A0A2G4F0D1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55224">
        <property type="protein sequence ID" value="PHX55224"/>
        <property type="gene ID" value="CP500_011840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="63"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="143"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="226"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="313"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="404"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="454" mass="50430" checksum="F68BFF197732ADA8" modified="2018-01-31" version="1">MESLAYLELALACQSPTESKISEGIKWKHLSSQTYVRLLSLALMLSVLSVAHSAFAQIDPGRPNLRSVQDRLRQLGYFNRTSTGQLGPLTQNALTNFQRDYQLSLTGRADRDTISALNTLASRAQPYRSVEINYRELRFGDKGEDVLVLQRELQQLGYFTAHPTGTFGRITQEAVRSFQQINRLSVTGVADSQTLALLLRVRTPVPPIPGVVSGNGGCRGLRFGDRGATVDLMQRQLKDLGYFEGRVDGKFRERTLYAVTRFQQDNFLVSDGCADSATLTAIDARRSEFETTFSPGEGRQQSFALDLLKFGDTGNQVELVQQRLQKVRYYAGPIHGLFDRATEAAVIRFQTNNRLLGTGVVDRQTQVALQRSHSRTAQKSPDRGLVLPQSDRASAVGISSSSRSSIYQLQRRLRDLSFYNGPISGVFDAPTRAALDQAQRSYGVSTDDLLTQTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0H8</accession>
    <name>A0A2G4F0H8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55256">
        <property type="protein sequence ID" value="PHX55256"/>
        <property type="gene ID" value="CP500_011790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="8282" checksum="47C030B8339D0CC8" modified="2018-01-31" version="1">MWRSARHLNLRLKLGRASAKPNTLLLNPAPAQVSRIDFVGWVERQRNPTHYFKRVGFRKALTQPTKSTFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0L8</accession>
    <name>A0A2G4F0L8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55314">
        <property type="protein sequence ID" value="PHX55314"/>
        <property type="gene ID" value="CP500_011460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="25"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12661" checksum="12489A586F101AAF" modified="2018-01-31" version="1">MEIKTEQYRICYDRETTTVSFLGSLRLSGPEEYQPIAKLLSDIADGDAGKITLNLQQLEFLNSSGISMLSKFVIGVRKKAGVQMVVQGSKSLAWQAKSLKNLQRLMPALILELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0N0</accession>
    <name>A0A2G4F0N0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55313">
        <property type="protein sequence ID" value="PHX55313"/>
        <property type="gene ID" value="CP500_011450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="2">
        <location>
            <begin position="347"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="660" mass="74927" checksum="F13DA754FCE97EF6" modified="2018-01-31" version="1">MKKTSLGINLMNRLSYPQKFTLIGFLFAMPLTLVIYLLISEINSQVNFAQKEILGNQYLRPLRELRQDIPKLQLLDYQPLNTNLNQPETRAELEAKIDSKFQNIANMDNSLQNILNGAEYFNKIYNNWQDFKHRRDEFSLETYDFLYQDLGADINTLSGHIGDSSNLILDPDLDTYYLMDATLLKIPEIQKVLSEIRILSERISLRSNATQATQDERTQFIGLSIKLRELNAALGINMGVAFKNNHYGNLEAKLSLDLESFNFLADQLASKVDKLNYPSVLIEHYAYIDASDRLLDSSFELWDKTIKELDSLLKRRIDNLVNKKKIISIVVLMSLGIVTYVFVSFYQAVMETVLVLDEASKKMASGNLNHKIILENKDELGQVVGSFNKIADALVYANLEITVLNDRLKSENMRMSAELDVTRKIQQMLLPKDRELKAVIGLDIAGFMESADEVGGDYYDVLQQDGRVKIGIGDVTGHGLESGVLMIMVQTAVRTLLAYNEPDPVRFLSAINRAIYDNVQRMKSDKNASLALLDYEAGMLKLSGQHEEMIVVRCNGSVERFDTIDLGFPIGLDVDITEFVAEKLVQLYTGDVVVLYTDGITEAENMDKMLYGLERLIEVVKINWQRTAGQIRHAVIDDVRSHIGEQKVFDDITLLILKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Y1</accession>
    <name>A0A2G4F0Y1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55398">
        <property type="protein sequence ID" value="PHX55398"/>
        <property type="gene ID" value="CP500_011025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7968" checksum="5BEE7AB2AE6DB90D" modified="2018-01-31" version="1">MDYRSFFVWSIAPMIFLATEKILDQREVGIGWVCAIERTNNIKLSDLTEINTESVQIMQNRAITISSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F101</accession>
    <name>A0A2G4F101_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent DNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245902">
        <property type="entry name" value="Tbo703ORF12190P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55137">
        <property type="protein sequence ID" value="PHX55137"/>
        <property type="gene ID" value="CP500_012190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="360"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="906" mass="103283" checksum="F386179F4809C22A" modified="2018-01-31" version="1">MPATPESLQKFVTYCQQNITGDEKGQAQVFLDHFFRAFGHEGALEAGATYEERIEKSSKKGQMGFADLVWKKHVLIEMKKRGEDLTKREHRTQTERYYIRLKKDDRPRYVMMCNFDEFHIYDFDVQPDEPLDIITLKQLPARSPAFAFMESTSRRPIFKNNQVEITEKAASRMGMLLEMLIERGKERKFAKFNQFQAQRFVLQCVLAMFAEDRGLLPPALFTRCVKDCLEGASSYDVLGGLFQAMNQQGITPAGRYEGVEYFNGGLFSEIHPIELQQGELKILEVCAEQNWSQVRPSIFGNIFESALKTDKKQRRAYGIHFTTEGDIRRIVLPTISYYWEERINAANTVAKLQSLHQELGRYRVLDPACGSGNFLYVAYQELKQVEKLLLDKLNECDGTRGYMNLVTPQQFYGMDINSFAVELARVTLMIGRKVAIDNLGLKEPSLPLDTLDKNIVCADALFTDWVKADAIIGNPPFLGGKHMRIALGDEYIDRVFERFPDVKDSVDFCAYWFRIAHNNLELNGRAGLVATNSISQGKSRAATLDYVAQNGGHIYAAVSTQPWSGEAKVHVSLINWSKEKPKVYYLDNLVVSSINSSLQATIDVSQAARLSANLNKCFQGIIPVGKGFIVTQPQVEDWVKADAKNQDVLKLFLMGANLAKNPNGMPERWIIDFSNMPIEEASNYELPLEHTRIHVKPEREQNREAIMREKWWRFKRTNEGMRKAIAPLSNYFTVPRVSKWAVFIPATVSWLPGDKSVVVASEDFYIFGILTSQVHRIWMHAQKSTLKADIAYTHNTCFETFPFPQTAAKQLVEEIRATAIELHQYRTQQMSAKQWGITQLYNKFFNEPSSQLYKLHAKLDRQVIQAYGFTDSDNILDQLLALNLELAETEKQGEPIVGPTAPNEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F106</accession>
    <name>A0A2G4F106_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55442">
        <property type="protein sequence ID" value="PHX55442"/>
        <property type="gene ID" value="CP500_010700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="18043" checksum="A9C3452F1464C04D" modified="2018-01-31" version="1">MDLDLQIRSLIDKAPPDGSTPEILEAIAPALRLLAEQLEHLEYCILQNFDQSWAIVLLSNLKQPGQEKKVIYAWTTLKDASQSIVAGDRLLPVLMPVTHILFQMLALEGLDSIVFFETPGNLETGTEVRREQVQNLINVYLQQYRSTLQSNFNNLPPDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F124</accession>
    <name>A0A2G4F124_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Queuine tRNA-ribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tgt</name>
        <name evidence="6" type="ORF">CP500_010765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA = 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:24104"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="EC" id="2.4.2.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55453">
        <property type="protein sequence ID" value="PHX55453"/>
        <property type="gene ID" value="CP500_010765"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:queuine tRNA-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101030">
        <property type="term" value="P:tRNA-guanine transglycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="SSF51713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGT" evidence="5">
        <location>
            <begin position="17"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="95"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="4">
        <location>
            <begin position="249"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="4">
        <location>
            <begin position="273"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="373" mass="41112" checksum="9553599B65FA10D9" modified="2018-01-31" version="1">MSEKFSFQCQANCSHTKARAGVFTTPHGVLETPKFMPVGTLANVKTLTPAHLKDAGSQMVLANTYHLHLQPGEHIVAGAGGLHKFMAWPGPILTDSGGFQVFSLSQMRTISEEGVTFRSPRDGRMINLTPERSIQIQNELGADVIMAFDECPPYPATRQEVESATDRTYRWLKRCIQAHSRPDQALFGIVQGGVYPDLRSRAANQLIDLDLPGYAIGGVSVGESGDLIAEIVKVTAPLLPPNKPRYLMGIGTYREMAVAVASGVDMFDCVIPTRLARHGTAFVAGGRLSLKNARFREDFAPLDESCPCYTCQNFSRAYLAHLARANEVLGYTLLAIHNVTELIRFTQRMREAIFADRFTEEFGHWLTPAVDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1D5</accession>
    <name>A0A2G4F1D5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2442 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55277">
        <property type="protein sequence ID" value="PHX55277"/>
        <property type="gene ID" value="CP500_011560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018841">
        <property type="entry name" value="DUF2442"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10387">
        <property type="entry name" value="DUF2442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10136" checksum="8910F10851D44EF2" modified="2018-01-31" version="1">MGILAIRADERVKHIHFTEETISVDLMDGRIITVPLIWYPRLFNATPDQRVKWEVCGGGYGIHWEEIDEDLSTEGMLRGAPAPRSKITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1G5</accession>
    <name>A0A2G4F1G5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)H-quinone oxidoreductase subunit J</fullName>
            <ecNumber evidence="2">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">NAD(P)H dehydrogenase, subunit J</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NADH-plastoquinone oxidoreductase subunit J</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NDH-1 subunit J</fullName>
            <shortName evidence="2">NDH-J</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ndhJ</name>
        <name evidence="6" type="ORF">CP500_009960</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 4">NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 4">Cellular thylakoid membrane</location>
            <topology evidence="2 4">Peripheral membrane protein</topology>
            <orientation evidence="2 4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the complex I 30 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55592">
        <property type="protein sequence ID" value="PHX55592"/>
        <property type="gene ID" value="CP500_009960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01357">
        <property type="entry name" value="NDH1_NuoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020396">
        <property type="entry name" value="NADH_UbQ_OxRdtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="SSF143243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00542">
        <property type="entry name" value="COMPLEX1_30K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="2 4" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="2 4" id="KW-0874">Quinone</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="2 3" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 2 3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Complex1_30kDa" evidence="5">
        <location>
            <begin position="39"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="167" mass="19384" checksum="4D875F234A1CACD1" modified="2018-01-31" version="1">MAETETSIVEAGKVSQWLTQNGFEHEALAADNLGVEILKVDRDFLIPMSTALYAYGFNYMQCQCAYDQGPGQDLVSVYHLAKLTDNASHPEEVRVKVFIPREDPRVPSVYWIWKAADFQERESYDMYGIVYEGHPNLKRILMNEDWVGWPLRKDYISPDFYELQDAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1K3</accession>
    <name>A0A2G4F1K3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55625">
        <property type="protein sequence ID" value="PHX55625"/>
        <property type="gene ID" value="CP500_009850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="11601" checksum="C193642931F60960" modified="2018-01-31" version="1">MTLTELKIDLASLNSADKAAAIEILLQTLSTGAIGIKKTPGVCGGDACVGNTRIQVWVLVGYRRLGCSDAELFKCYPHLTAADLVNAWAYADAYPEEIEQAIKENEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1M0</accession>
    <name>A0A2G4F1M0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF29 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55642">
        <property type="protein sequence ID" value="PHX55642"/>
        <property type="gene ID" value="CP500_009525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002636">
        <property type="entry name" value="DUF29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34235">
        <property type="entry name" value="PTHR34235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01724">
        <property type="entry name" value="DUF29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="165" mass="19376" checksum="3B56C4884AC57A36" modified="2018-01-31" version="1">MQTPQVKKTPKNSMQSLYETDFYAWTEEQVKLLKHQEWSQIDLPNLIEEIESLGKQQRAELRNRLSILIGHLLKWEYQVSKRSRSWVNTIRIQRMDLLELLKENPSLKPYLQEALQTAYIKGLALASGETDLPRTTFPENCPYGLEDIFSDRFYPGEPETNDVMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1P5</accession>
    <name>A0A2G4F1P5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_009655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55665">
        <property type="protein sequence ID" value="PHX55665"/>
        <property type="gene ID" value="CP500_009655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021147">
        <property type="entry name" value="DUF697"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05128">
        <property type="entry name" value="DUF697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="3">
        <location>
            <begin position="63"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="482" mass="52429" checksum="5582C4C148014377" modified="2018-01-31" version="1">MADKSTQENRLSLARASLRQSLARHAHLRQSKKNSNPKLEATLQNQLDILTFTSEKLNQNIIRIATFGLVSRGKSAVLNALLGQKILQTGPLNGVTQWPRSVRWAVPLSLNNDESGGIQIELIDTPGIDEIGGEVRGEMAKQVTRQADLILFVVAGDITRTEYQALCELQTAQKPLILVFNKIDLYPELDRKAIYKSLQALGNAEQLAADAATDKSDSENLSPDNSAPKSTAKSAPKNTKSLEIVMVAAEPAPMQVRVEWPDGRITHEWESPPPQIDELKQKILTILNREGRSLLALNALIEARDAEANIAHQILKLRQTEAEDLIWQFAKYKALAVGLNPIAFLDVMGATVADLALIRSLSRLYGLPMTGYEAGKLWQTIFSSAGGVLLGELGSSFLLGFGKSAAIAAPQIGFSTFAGVAVTQASLAAYGTYAVGRAAQVYLEKGCTWGPLGQDTVIQEIVSTIERDTIANRLKQELKLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Y7</accession>
    <name>A0A2G4F1Y7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative toxin-antitoxin system toxin component, PIN family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55755">
        <property type="protein sequence ID" value="PHX55755"/>
        <property type="gene ID" value="CP500_009120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002850">
        <property type="entry name" value="PIN_toxin-like"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00305">
        <property type="entry name" value="TIGR00305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7945" checksum="33F9ECF07A8A9FD3" modified="2018-01-31" version="1">MKLKQGIILYSQATLNELEQVLNRKNFNKYLSLEDRQLFLFKFISSSQLVSLTENITVCRDEKDNKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F239</accession>
    <name>A0A2G4F239_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55808">
        <property type="protein sequence ID" value="PHX55808"/>
        <property type="gene ID" value="CP500_008965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8002" checksum="CA48FB076C63B311" modified="2018-01-31" version="1">MNTLLLYRKVIANKPNLVVANRNCNSISKCTFCTHYKMQTGSVGQCQLLNAPVLGAWKSCSLGKPVFTPNWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F291</accession>
    <name>A0A2G4F291_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55880">
        <property type="protein sequence ID" value="PHX55880"/>
        <property type="gene ID" value="CP500_008265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="169"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="482" mass="54747" checksum="82D770AD4B2771F3" modified="2018-01-31" version="1">MDVQEVLKLADELAVDKTGKYLDDIQKDTLRGIWERKKYLEIAKASNCSETHIKKVASKLFRLFRDRLTDKKLKKTNFRATMERYEISQCSNFVNFNIVQKSNINNFCPETSHPPKTPKNSPPTQTSTEDETQQKPRLDLRDAPELKTFYNYPNSPLTTLENSIAHQNCHLLTITGMTGTGKSAIARNLIPQIQTQFDRIIWRSLRTSPPLETTLKTLIQFLSNQNPPNPPLPRGGEGGVFPANTDDQLSILIETLRENRCLIILDDVQQILSSGQLSGNYKPGYENYGTLFKLIGEIPHNSCLILNSWEPPSDILTFTDDNSAVCLLQLTGLGEAATEILREKGLLDEEYWPELIEFYQGNPLWLKLVAQTINNLFSGRVSQYLSYQPVFLSDELTPILQQHYQRLSEIEKQVISQLSNEIEPVSFTQFMAKCQGSQGELFKAIQSLARRGTIEKLSCETETVFTIPPVLKQYVKMVADPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2D0</accession>
    <name>A0A2G4F2D0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55627">
        <property type="protein sequence ID" value="PHX55627"/>
        <property type="gene ID" value="CP500_009865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="202" mass="23260" checksum="42759F07EC39E37A" modified="2018-01-31" version="1">MNQQAKQDIDSADTFESDLAQLSETIRKSKWASSQLDGIVTDGLEVAKETDAIYYEEGIFTQFRLYLLYKVAFKLWSYQHQTILQILESGKSEQLKKNSQLVLRHHNVMINMFDDLNQLASVSDPNSLRDSWLSVWTQTISELTKFVDIPRVYPVKQKNQNFFGFKLAMKLPDMSGNTKYVILSTFLLVLAIPIALFLLSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2H0</accession>
    <name>A0A2G4F2H0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aromatic ring-hydroxylating dioxygenase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_008215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55946">
        <property type="protein sequence ID" value="PHX55946"/>
        <property type="gene ID" value="CP500_008215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044043">
        <property type="entry name" value="VanA_C_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19112">
        <property type="entry name" value="VanA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="13"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="339" mass="38725" checksum="8B5469A3192E32DC" modified="2018-01-31" version="1">MLVTKQAVFKRFWYPVIPTVELSGEPKAFELLGEPIVLWLDSEGKPAAVEDRCCHRTAKLSLGKVVGGNICCAYHGWTFNSSGTCVRVPQQQNDTISPNYKVKAYRTCDRYGYVWVCLGEPLTDIPEIPEAADSNYRQIHEFYERWNCAGLRVMENELDMAHPTFVHTTTFGSEAHLTPDVMEFQETEWELHYHSVLGVVNPAQQQQNLKIEEQETVRTIDGIWFMPFTVKLRIVYPNGLVHIIVNTMTPINDSASQMVQFCLRNDTETDAKTSDIIAFDRAVTLEDKRILETTDWDVPLDINQEQHMLTDKPGIIMRRKIAALLKAHGEVEQTKVISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2I3</accession>
    <name>A0A2G4F2I3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">23S rRNA (Uracil(1939)-C(5))-methyltransferase RlmD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_007960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55971">
        <property type="protein sequence ID" value="PHX55971"/>
        <property type="gene ID" value="CP500_007960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="PTHR11061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="6">
        <location>
            <begin position="16"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="470" mass="52461" checksum="007464E01318AC91" modified="2018-01-31" version="1">MTKSNFPILSQKPVNPCQQGQLIEIDITDLADTGDGIGRFEQLVVFVPDTVPGDRVAVRLQQVKSTYATAKLETLIKLSEHRIRPNCIVADKCGGCQWQHVNYDYQLKTKQNQVIQALERIGGFSDLPCDEILAGKIDNFPQFLGYRNKATYPLARSVAGQVQAGYYQKGTHKLVNLNQCPVQDPRLDPLLKDVKEDIHWMKWPVYDEKEHTGEVRHLSLRIGRRTGEILLTVIARTGDLPGLETQASDWLKSYPKLVGVCLNINAAKTNVIFGSETRCIAGRPFLREEFAGLEFQLRANTFFQVNTEAAEGLLQVIAAELNLQGNEILVDAYCGIGTFTLPLAKQVQIAIGLEVQPEAIAQAELNAQLNDLTNVTFHVGTVEELLPQLGLKPDIVLLDPPRKGCDRTVLETIKEMQPNRIVYVSCKPATLARDLKFLCENGDYKLVRVQPADFFPQTSHVECVAFLVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2M9</accession>
    <name>A0A2G4F2M9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3386 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56021">
        <property type="protein sequence ID" value="PHX56021"/>
        <property type="gene ID" value="CP500_007660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021809">
        <property type="entry name" value="DUF3386"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11866">
        <property type="entry name" value="DUF3386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="216" mass="24639" checksum="D18C06FC87A39E96" modified="2018-01-31" version="1">MTETANARDLFRAAYEHRYTWDANFPGYSADIELKQGDEVYTGHVSIKPDMTVEVSGIADEEVQQSVYTQMRDIVTHRKRSTFEKSHGKNNFTLGEKDDTDAVDILVQGDSMGSNYKIRGLSICQVSRVMGRMAFVIDTHNSLETPEGSLASHYDAVFRNPETDEIIRELEFEDTFEKIGDYYVMTKQVVRSKEKGQFTTTEFNYSNVKMLEPAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2S4</accession>
    <name>A0A2G4F2S4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56035">
        <property type="protein sequence ID" value="PHX56035"/>
        <property type="gene ID" value="CP500_007745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008868">
        <property type="entry name" value="TniB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05621">
        <property type="entry name" value="TniB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="358" mass="40922" checksum="2AF00A9E99368719" modified="2018-01-31" version="1">MGRSLKLSPGCIEQVKSAVGRNGFPSQKALAEELEISLSTVKSFLAGKPVDYSYFLEISERLGYEWRKIVHIDETIAKSIFKETSAFITGTPITNPRYFFGRQKELKRLFNLLKRPPLQNAAIIGKRRSGKTSLLQYLKNITTTPTEKLRPGQKSDWLPYPENYRWIFVDFQDPRRQNREGLLRYILESLKMQVPNPCDLDRFMDVVSSNLHQPTIILLDEIGVGLQRCPELDDEFWESLRSLAPQTNGNLGFVLATPESPLELARNTGHSSPFFNIFGSTTILGALTEGEARELIASSPIPFPDGDVEWILTQSERWPLLLQILCRERLFSLEEEEIGDDWREEALEQLKTFADLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F339</accession>
    <name>A0A2G4F339_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_006855</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56158">
        <property type="protein sequence ID" value="PHX56158"/>
        <property type="gene ID" value="CP500_006855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013733994" description="Superoxide dismutase" evidence="7">
        <location>
            <begin position="27"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_N" evidence="8">
        <location>
            <begin position="50"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="9">
        <location>
            <begin position="144"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="250" mass="28062" checksum="62F0F362ECB99791" modified="2018-01-31" version="1">MTHKRRDFLYLLTASVGAITTGACQASGNNLPQANPTTEATKIAQTPALFTLPPLPYEYNALEPHIDGRTMQFHHDKHHAAYVKNLNDAVSKYPQLKNMSAEDMLRDLSKVPEDIRTVVRNNGGGHVNHSMFWEIMSPKGGGEPTGALATAIKQSFGSADAFKAKFNDAGTKRFGSGWVWLVRTKAGKLQIATTPNQDSPFMDGNYPIMGNDVWEHAYYLKYQNLRADYLKAWWNVVNWTEINKRYEKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F391</accession>
    <name>A0A2G4F391_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="6 12">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CP500_006435</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 12">
            <text>a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9517"/>
            <dbReference type="Rhea" id="RHEA-COMP:9527"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>a dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:9517"/>
            <dbReference type="Rhea" id="RHEA-COMP:9527"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="6 12"/>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56243">
        <property type="protein sequence ID" value="PHX56243"/>
        <property type="gene ID" value="CP500_006435"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="GlyclTrfase_39-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="Glyco_trans_39/83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="PTHR10050"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="462"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="PMT" evidence="13">
        <location>
            <begin position="23"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_4TMC" evidence="14">
        <location>
            <begin position="282"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX56243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="504" mass="57993" checksum="50BEE79CB3514E5F" modified="2018-01-31" version="1">MKFNKQPFNKSTWIFPLGMLGVFLVSFTLRFWELERFNTLVFDEVYYAKFANDYLTKTPFFNAHPPLSQYIIAIGIWLGTHLPFGKTAINTMAGSQLSPWDYRWLNALTGSFIPLVVGALAYQLVKRHSYAFIAALFAACDGLFLVESRYALNNIYLVLFGILGQLFILKSVEAEGKKRWNCLILAGVFFGASAAIKWNGLWFLLGTYLILICAWIVRFIQKNRGELDLINQDFSELLPAESPIQKLTKLNFLEVGLSLAIIPIVVYSISWIPHLQLNPTPDFWQMQTEILTYHQRIKSGPDVHPYCSAWYGWPLMLRPIVYFYKTATNNAPPDPVLPSLPIGATKAIFDVHAMGNPALWWLSTLALILVIGILVHRLWVWLETRSEASVELLEQHQPIVFPPTTEMWLILYLIVNWMANLLPWVKVTRCVFLYHYMGCSVFATLALAWWVDRWLHSPQTRLRGMGVTAIFLVLGGFAFWMPIYLGLPLSELEWKIRMWLPSWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F396</accession>
    <name>A0A2G4F396_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">uraD</name>
        <name evidence="8" type="ORF">CP500_008220</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) = (S)-allantoin + CO2</text>
            <dbReference type="Rhea" id="RHEA:26301"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15678"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="4.1.1.97"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; urate degradation; (S)-allantoin from urate: step 3/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.97" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55947">
        <property type="protein sequence ID" value="PHX55947"/>
        <property type="gene ID" value="CP500_008220"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00394">
        <property type="reaction ID" value="UER00652"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000255">
        <property type="term" value="P:allantoin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019628">
        <property type="term" value="P:urate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018020">
        <property type="entry name" value="OHCU_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017580">
        <property type="entry name" value="OHCU_decarboxylase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036778">
        <property type="entry name" value="OHCU_decarboxylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09349">
        <property type="entry name" value="OHCU_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158694">
        <property type="entry name" value="SSF158694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03164">
        <property type="entry name" value="UHCUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OHCU_decarbox" evidence="7">
        <location>
            <begin position="9"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="166" mass="18728" checksum="A4F201C99DC586F3" modified="2018-01-31" version="1">MPYSLVELNQLSQEEFTQALGAIFEHTPDIARRTWDDRPFASTADLHAKMVTVVSAMTEAEKLALIQAHPDLGSKAKMAAASVSEQAGAGLDKLSVEEFDRFQYLNRSYREKFDFPFIVAVKNHTKTSILAAFKQRLDNSWETEMQQAVAEICEIARFRLESAIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3B0</accession>
    <name>A0A2G4F3B0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsH</name>
        <name evidence="8" type="ORF">CP500_006255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cellular thylakoid membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Stromal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56264">
        <property type="protein sequence ID" value="PHX56264"/>
        <property type="gene ID" value="CP500_006255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="189"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="197"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="500"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="612" mass="66959" checksum="9D54F96C2A3904F0" modified="2018-01-31" version="1">MNKRWRNAGLYALLAIVVIALATAFFDKPQQSKEVWKYSQFIQEVEAKRVDKINISSDRSKALVTAQDGNKVIVNLPNDPELINILTKNNVDISVLPQNDEGFWVKALSSLFFPILLLVGLFFLVRRAQNGPGNQAMNFGKSKARVQMEPQTQVTFSDVAGIEQAKLELAEVVDFLKNADRFTAVGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFEQAKTNAPCIVFIDEIDAVGRQRGAGMGGGNDEREQTLNQLLTEMDGFEGNTGIIIIAATNRPDVLDAALLRPGRFDRQVTVDRPDFAGRLEILNVHARGKTLSKDVDLEKIARRTPGFTGADLANLLNESAILAARRNLTEVSMDEVNDAIDRVLAGPEKKDRVMSEKRKTLVAYHEAGHALVGALMPDYDPVQKISIIPRGRAGGLTWFTPSEDRMDSGLYSRSYLQNQMAVALGGRIAEEIVFGEEEVTTGASNDLQQVARVARQMVTRFGMSDVLGPVALGRQQGNMFMGRDIMAERDFSEKTAAAIDNEVRLLVEQAYRRAKDVLVGNRHVLNALADMLVEKETVDSDELQNLLANSDVKMATIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3F3</accession>
    <name>A0A2G4F3F3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3593 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56251">
        <property type="protein sequence ID" value="PHX56251"/>
        <property type="gene ID" value="CP500_006485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021995">
        <property type="entry name" value="DUF3593"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35473">
        <property type="entry name" value="PTHR35473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12159">
        <property type="entry name" value="DUF3593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10610" checksum="138AB1568C82CE4B" modified="2018-01-31" version="1">MFSKESLFVLSLFPYLGFLWFLTRSGKMPRLALIGFYGTLVFVGVTIPAAIYAKVAYNESLANVDWLHGSAEFFLTLANILVVLGFREAVIKAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3G7</accession>
    <name>A0A2G4F3G7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAGPA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56299">
        <property type="protein sequence ID" value="PHX56299"/>
        <property type="gene ID" value="CP500_006090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018711">
        <property type="entry name" value="NAGPA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09992">
        <property type="entry name" value="NAGPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAGPA" evidence="2">
        <location>
            <begin position="544"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="699" mass="75663" checksum="C5DC67AF2F1F8261" modified="2018-01-31" version="1">MSNFFTPEFNNESAIAPWNASLEPTKAIIPKLDANPVLTGGIGQEVNIPTLTPEAYDNIILPDASLTRMASAVNTDSNSSLPDSSVDLLTGQAMSEVYGDLSKFAADPDFAAKLNVPFGENWDAAAAKTLAEGWFQGDFSDIPPVKIVSSGEIGGANGAFAAATDTIYVSKEFLARNAANPVAVADVLLEEIGHSVDARLNVTDSPGDEGAIFGAIVQGKELSEGELQGLKSKDDTATVVLGGEDTTIEMNQQRWTVWRYADWRNSNFNWQRPDGSSDQNGNRPDGKDGIKINWGQGSPFDTANIGFIDKADYFATSGVTTAYFDAGATYKFRVSGDDYIVMSARQVNQQGFNWITPVSQDGKQPQLQRFPNGIFQEYSWTPTQSGQYYVFFQHYEVTGDADIDISWEKTGQAQSDSAPAGFTSVKSAKGVNLYESADKSDYVQVVDLSQGASIKLLTGQQTGDTQTGYYGGTSATFKRNPIESFWNKLSSENANAFSVSNGAFFERVLPFIQPDTELSYPLKFFSSTGYSNVDFLPPVYSYDGSKNVQFAEVNKNNKLKLEIWEDRASITKFDEDTNIKSLENSSAPQAIVGLDPKVVDDGATSRTFIGVKDRDSNGTNETFLILNSKDRTKTAANQILMNFGASKVMALDGSGSTQMTAKGEAEAFVKSSDLSRFGTDGFRIGVARYIPQAIGVVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3K9</accession>
    <name>A0A2G4F3K9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cobyrinate a,c-diamide synthase</fullName>
            <ecNumber evidence="3">6.3.5.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Cobyrinic acid a,c-diamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cbiA</name>
        <name evidence="6" type="ORF">CP500_006035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2 ATP + cob(II)yrinate + 2 H2O + 2 L-glutamine = 2 ADP + cob(II)yrinate a,c diamide + 2 H(+) + 2 L-glutamate + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:26289"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="ChEBI" id="CHEBI:58894"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 10/10.</text>
    </comment>
    <comment type="domain">
        <text evidence="3">Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CobB/CbiA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.11" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56342">
        <property type="protein sequence ID" value="PHX56342"/>
        <property type="gene ID" value="CP500_006035"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00231"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00027">
        <property type="entry name" value="CobB_CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="PTHR43873"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00379">
        <property type="entry name" value="cobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="4">
        <location>
            <begin position="3"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="5">
        <location>
            <begin position="301"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <feature type="site" description="Increases nucleophilicity of active site Cys" evidence="3">
        <location>
            <position position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="508" mass="55820" checksum="F0B045649E659EB6" modified="2018-01-31" version="1">MALVIAGERSGVGKTTVTIALLAYLMRHGLNVQSFKVGPDYIDPMFHAFVTGRPCRNLDAILTSESYVQKCFYRHIQDVNYALVEGVMGLFDGVNRRKKGSAADFVTDVTDVTDVTDVKDRRKAEGKEEDNYDFSFASTAHVASLLNLPILLVIDCSRLSGSVAAIAHGFRSFDKNLNFAGLVLNRVASDRHLELLTNALEPLDLPILGVLRRDEAVTIPDRHLGLIPAEELPNLEAAIDKLADLAAVAFDWEKLLPMLAVNSNGGGEGCEQLLGRYSPPSTIVTEKDDVVNSLEGKFGVRIAVARDRAFNFYYQDNLDLLAELGAELVFWSPVDDAVFPDNVQGLYFGGGFPEVFAKELSGNVVIRDAVRSAIFAGMPTYAECGGLMYLCDSIVDFEGNSWQGVGVLKSNAEMGKRLTLGYRETVALRDSCVLVAGDEVCGHEFHRSHLSVEPTNPVYHSWRYGKRGEVEQVGEGWGVYQVHAAYLHLHWGARPDIPARFLQRCADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3N3</accession>
    <name>A0A2G4F3N3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56356">
        <property type="protein sequence ID" value="PHX56356"/>
        <property type="gene ID" value="CP500_005800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16412">
        <property type="entry name" value="dndB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017642">
        <property type="entry name" value="DNA_S_mod_DndB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14072">
        <property type="entry name" value="DndB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="392" mass="44174" checksum="531807D971A3C7D5" modified="2018-01-31" version="1">MPENNYPVTDSIQKLDEVLEPYFAKYHRQKCYPGLIFQQGKRKMVQINIPADDLPTLLQAKPSTGNDPDSGKNRPEIKGHAEEVKQYILKRTRNDQPWILGTLTANVDPEKIDIIELGRGICLVVIHRGVKLDITDGQHRKRAIHELIESGDGELIGDNDFPITLVLEEDFNQCQADFRDMAQTKQLDKSLLLSFGEFEGRVGITKNLLEKVLMFHGKTDKIKTNPDSKRKLIYTTNFIAKLVSCAFTDGPIDELKDYDVAESSNILAICLNNLFSECSQTRHICEASVEDLTVEDVNKFKEYCILGRSVGLEVLGRLLYYTYDTDSSQDFDTEKIAELAQLDWSRQSHVWEGNIVLSNSSPKNPKASYKITASASAVKMAVEAAKAELGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3U5</accession>
    <name>A0A2G4F3U5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sua5/YciO/YrdC/YwlC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56419">
        <property type="protein sequence ID" value="PHX56419"/>
        <property type="gene ID" value="CP500_005270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="196" mass="20808" checksum="D7F3971906837076" modified="2018-01-31" version="1">MTQVSIDSLIQGAISGDYIVSFPTDTVPALAALPDRSELIFVAKQRSQDKPLILMAGSAEDLWPYVHGSPADFQVWQQVAQSFWPGALTLVLPASEKVPAAMNAIDPTTIGVRVPNCVLARKILQQTGPLATTSANLSGQAPLESIAEIEAQFPEVLTLLASQLSTVATASSLPSTVAKWTGSGWKILRQGTVQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3X8</accession>
    <name>A0A2G4F3X8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56187">
        <property type="protein sequence ID" value="PHX56187"/>
        <property type="gene ID" value="CP500_006675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="10016" checksum="A3BD978B4705A36F" modified="2018-01-31" version="1">MYLTDRQILTFWQTFLPDRLFRDFALKYYLLTPYHIHGYLSISAIDYSLTFDTKQNLPSHYFTRRMQQSFFTETDHCYHVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F400</accession>
    <name>A0A2G4F400_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_005215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56490">
        <property type="protein sequence ID" value="PHX56490"/>
        <property type="gene ID" value="CP500_005215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="325"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="532"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="357"/>
            <end position="364"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="566" mass="63837" checksum="426FC044AEF18B26" modified="2018-01-31" version="1">MLRLEHISKIYPTGVVLKDVTWEVKPGDRIGLVGVNGAGKSTQLKIIAGEIEPTAGEVIRPASLHIAYLSQEFEVDPTRTVKEEFWRAFSEANEVHESLMQVHRDLENSTPENLDELIHKMDRLQRQFEGLNGYGLEAQIEKILPEIGFEAEDSDRLVSAFSGGWQMRMSLGKILLQKPDILLLDEPTNHLDLETIEWLEVYLRGLTTPMVIVSHDREFLDRLCTQIVETERGVSSTYLGNYSSYLLQKAEAREAQLNAYENQQKELDKQQAFVEKFRASATRSTQAKSREKQLDKIERIEAPTGGLKTLHFRFPPAPRSGREVVIIEDLVHSYGDKILFLGADLLVERGDRIAFLGPNGAGKSTLLKMIMGSETPTEGTVKFGGHNVIPGYFEQNQAEALDLNKSVMATIHDEVPDWKNEEVRTILGRFLFTGETVYKNVGALSGGEKARLALAKMLLTPVNLLILDEPTNHLDIPAKEMMEEAIKNYDGTVMIVSHDRYFISQVANKIVEIRDGEFRPYLGDYHYYLDKIAEEKELAKIAKLEAEKAAKKAEKEAKKKATAKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F402</accession>
    <name>A0A2G4F402_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">L-aspartate oxidase</fullName>
            <ecNumber evidence="4 10">1.4.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nadB</name>
        <name evidence="13" type="ORF">CP500_005135</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the oxidation of L-aspartate to iminoaspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + O2 = H2O2 + iminosuccinate</text>
            <dbReference type="Rhea" id="RHEA:25876"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="1.4.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:25877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4 10"/>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56476">
        <property type="protein sequence ID" value="PHX56476"/>
        <property type="gene ID" value="CP500_005135"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044318">
        <property type="term" value="F:L-aspartate:fumarate oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00551">
        <property type="entry name" value="nadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 10" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="11">
        <location>
            <begin position="14"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="12">
        <location>
            <begin position="433"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX56476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="557" mass="61404" checksum="732330F9FB0A8DB3" modified="2018-01-31" version="1">MPRLTSLDIPPHFDIIVVGSGAAGLYAALCLPAHLRVGLITKDAIHTGSSNWAQGGIAAAIDPSDTPTLHLEDTLNAGVGLCDPEAVKFLVENAPAAIAHLLEMGVAFDRKGEKLAMTLEAAHSRPRVLHSADTTGRAIIETLTAKVRERPNIQVVSQAVALSLWLTPQKDRVQGISLLYQSQIRWLKSSAVILATGGGGQVFTQTTNPKVSTGDGVALAWRAGAVLRDLEFFQFHPTALTKPGAPHFLISEAVRGEGAHLIDDRGYRFAFEYHPAGELAPRDVVSRAIFHHLHKTAADPTHAHVYLDLRPIDPDRIRYRFPNIINVCQQWGIDVFQEPIPVAPAAHYWMGGVACDLMSQTSIRGLYAIGETASTGVHGANRLASNSLLECVVFAAQLSRIEIEPILVEPDSDSLMRVNSDWQGEMEKIASIRQMLPSLMWENAGISRQGEWLELALKQVNDWREMLASLKIVEFLVNLSPQQRIQLDSTDAEEQLRIVAETLNLLDLSYLILRSAVWRNESRGGHYRSDYPQTSENWEVHTLVHGYSLNTGKRWTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F427</accession>
    <name>A0A2G4F427_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Precorrin-2 C(20)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_004895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56498">
        <property type="protein sequence ID" value="PHX56498"/>
        <property type="gene ID" value="CP500_004895"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030788">
        <property type="term" value="F:precorrin-2 C20-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11645">
        <property type="entry name" value="Precorrin_2_C20_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012382">
        <property type="entry name" value="CobI/CbiL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006364">
        <property type="entry name" value="CobI/CbiL/CobIJ_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036427">
        <property type="entry name" value="Precrrn-2_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01467">
        <property type="entry name" value="cobI_cbiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR036427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="236" mass="25844" checksum="7996E647BB8A2446" modified="2018-01-31" version="1">MTETTGKLYGLGIGPGDPELITLKAYRILQSVPVIAYPAMENGKVLARSIVADYLRPEQIEIPMPLPFSPTRSSQPYYDIAAEKIAAHLSEGRDVAVLCEGEPFLYGTFMYLFNRLSGKFTTEVVPGISSTMASASALGVPLTYRNDVLSIMPATLDAEVLRDRLAVADAAVIIKLGRHFAKVRDVLIELGQFDRALYIERATMPNQVIRAIADVDPAVVPYWALVMIPSQQKSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F431</accession>
    <name>A0A2G4F431_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56495">
        <property type="protein sequence ID" value="PHX56495"/>
        <property type="gene ID" value="CP500_005245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="PTHR11409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="345" mass="39592" checksum="E34C6AB3AC422EDE" modified="2018-01-31" version="1">MTLHAELHRHLGGSVVPSVLWRYFDRHNADMVDRFQEYSKFEEFYTRRRNTLDEYLELHTLVESVQTVETLPYFIYRLMRGAYVFENLAYLELRYTPYLRTPEHLSQSERIDLMAEIVRVVGKASQISDCPIVTSQILCMHSRLPYEVNRAIVDLAAQMGEYVCAIDLAGGDAAIGDRLDEFVGLYQYARSIGIKTTGHLYETTSGCYPELLPYLMRIGHGIQIPLKYPELLPEVARRGQCLEVCPTTYLKTGTLQDMRELKVVFDRCFEAGVDIAICTDNAGLHNVRLPFEYENLLTLDIIDFRQLQACQNAAFRHAFAWPYGEQPAQMLTGLLQHESVCAIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F432</accession>
    <name>A0A2G4F432_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dnaK</name>
        <name evidence="11" type="ORF">CP500_004655</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="7">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56544">
        <property type="protein sequence ID" value="PHX56544"/>
        <property type="gene ID" value="CP500_004655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="512"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="596"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="512"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="7">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="632" mass="67591" checksum="4CB9A9B88B5DBBC4" modified="2018-01-31" version="1">MGKVVGIDLGTTNSCVAVMEGGKPTVIANAEGGRTTPSVVAFAKNGDQLVGQIAKRQAVMNAENTFYSVKRFIGRRVDEVTHETTEVSYKVLKVGNSLKLDCPARGKQFAPEEISAQVLRKLVEDASKYLGETVTQAVITVPAYFNDSQRQATKDAGKIAGIEVLRIINEPTAAALAYGLDKKSNETILVFDLGGGTFDVSILEVGDGVFEVLSTSGDTHLGGDDFDKKIVDFIAGDFQRAEGIDLRKDKQALQRLTEAAEKAKIELSSVTQAEINLPFITATQDGPKHLDMTLTRAKFEELCSDLIDRSRIPVENAIRDAKLDKSAINEVVLVGGSTRIPAVQELVKKILGKEPNQTVNPDEVVAVGAAIQAGVLSGEVKDILLLDVTPLSLGVETLGGVMTKIIPRNTTIPTKKSETFSTAVDGQTNVEIHVLQGEREMANDNKDLGTFRLDGVPPAPRGVPQIEVTFDIDANGILNVAAKDKGTGKEQSISITGASTLPSNEVDRMVREAESNASADKERREKIDRKNQADSQAYQIEKQLAELGDKVPADDKTKVEGLIKDLRDAINSEDDDRIKTLTTELQQAFYAVSSSLYQQAGGPTDGPGGPGDGGPTGGGDDVIDADFTEGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F487</accession>
    <name>A0A2G4F487_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56297">
        <property type="protein sequence ID" value="PHX56297"/>
        <property type="gene ID" value="CP500_006080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="5"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="13109" checksum="0FDCF1A267661DE6" modified="2018-01-31" version="1">MAISLYMDVHIPQAITEQLRRRGVDVLTAMEDGSTELPDDELLERATQLGRVLFTHDILFKAMAQDWQRQEKQFAGLIFGHQLGGTIGQFVKDLELIALVSESDEWMNAVEYIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4C6</accession>
    <name>A0A2G4F4C6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2079 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56610">
        <property type="protein sequence ID" value="PHX56610"/>
        <property type="gene ID" value="CP500_004555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018650">
        <property type="entry name" value="STSV1_Orf64"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09852">
        <property type="entry name" value="DUF2079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="530" mass="59341" checksum="D072CC0B4A765B51" modified="2018-01-31" version="1">MQNSSNFVDSDEESNVSNQENVEKGRSRPPSSLLMAIAIFATILFLCSSLRHALFQSTAFDLGIFDQAIYLISQNQTPFSSLMQMHILGDHAAVIYYPLALLYKIYPDVHWLFLVQAVALSLGALPSWSLARLAGLTKAQSRAIAFIYLLYPVVFNINLFDFHPEVIALPALLAAILAARLNKIIWFGSAVLLVLSCKAVLSLTVAAMGFWLLVCEKKRRCGAIAILLGIAWFLIASQKIIPLFSGSEVAGVGRYSYLGKSVLEIVINLILKPQLVLGKFLSFDTFKYIFILSLPVIWGLLPFSRKTGLRYLTPLIPAIPTLAINILSDLPFQRSLAYQYSVPIIPFLLLAVISKEGSAADFVADLADVGKREGSAADFVADLADVGKRGKFSRIPQFWLGMQLPKTMIIWSLIIFLFLGEYKDFFLYLNRLDTWQATREAIAQIQPQSSILTDNRLAPHFTHRPIVKLLSQISPQTDLAEFQYILLNQRHPWPDTAKIGNDLANQLQNTPKFQLTYQKNQVLLFKRIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4D5</accession>
    <name>A0A2G4F4D5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <shortName evidence="7">DXP reductoisomerase</shortName>
            <ecNumber evidence="7">1.1.1.267</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">1-deoxyxylulose-5-phosphate reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dxr</name>
        <name evidence="11" type="ORF">CP500_004550</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56609">
        <property type="protein sequence ID" value="PHX56609"/>
        <property type="gene ID" value="CP500_004550"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="SSF69055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DXP_reductoisom" evidence="8">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="DXP_redisom_C" evidence="9">
        <location>
            <begin position="146"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DXPR_C" evidence="10">
        <location>
            <begin position="261"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="396" mass="43006" checksum="88E0A9C829B38D9B" modified="2018-01-31" version="1">MKAITLLGSTGSIGTQTLDIVAQYPEQFRIVGLTAGRNVTLLAQQIRQFRPEIVAIGDENKLVELKEAIADIDPQPIILAGETGVVEVARYGDAEAVVTGIVGCAGLLPTIAAIQAGKDIALANKETLIAGGPVVNPLIEKHGVKILPADSEHSAIFQCLQGVLPGSLRRIILTASGGSFRDLPIEKLAEVTVADALKHPNWSMGQKITIDSATLMNKGLEVIEAHYLFGMDYDDIDIVIHPQSIIHSLIELQDTSVLAQLGWPDMRLPLLYALSWPERIHTDWKPFDLVKAGDLTFREPDHKKYPCMQLAYAAGRAGGSMPAVLNAANEQAVALFLEEKIQFLDIPKLIEKACDKHQPDNCESPGLDDILAADKWARQEVLVESMELGARILSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4K2</accession>
    <name>A0A2G4F4K2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative mRNA interferase YoeB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_004080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YoeB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56679">
        <property type="protein sequence ID" value="PHX56679"/>
        <property type="gene ID" value="CP500_004080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009614">
        <property type="entry name" value="YoeB_toxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38039">
        <property type="entry name" value="PTHR38039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06769">
        <property type="entry name" value="YoeB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02116">
        <property type="entry name" value="toxin_Txe_YoeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="12605" checksum="91A7B52211B050B2" modified="2018-01-31" version="1">MAKKRKQEPQETPEPEKTAVRDAVFQPKFLEDLTYWVEVDRKVALRFLKLVEAIVRDPFTGIGKPEPLKYLAAGTWSRRLTQEHRIVYLVSENRIDFIQARYHYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4K7</accession>
    <name>A0A2G4F4K7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56690">
        <property type="protein sequence ID" value="PHX56690"/>
        <property type="gene ID" value="CP500_004145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="80" mass="8822" checksum="34D4E84928DFF9EC" modified="2018-01-31" version="1">MLVVSCYLGIGHWALGIGDFKLLFVIIFEGLPITNYQLPIPDARCPMPDARCPMPDARCPITMIRYSMPLVVGRGNSNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4N2</accession>
    <name>A0A2G4F4N2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56699">
        <property type="protein sequence ID" value="PHX56699"/>
        <property type="gene ID" value="CP500_004200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12938" checksum="D35BEC866862256C" modified="2018-01-31" version="1">MTTPTRLEFPIAKAQYLFASATEPGKGGDKQKFWREVMGFESPEAIREAIIAQISLDLLQPVGQNDYGERYQAIILVTVRSGVSWQIRTGWIVLFGEDIARFVTAFPQRFGRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4N4</accession>
    <name>A0A2G4F4N4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2281 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56698">
        <property type="protein sequence ID" value="PHX56698"/>
        <property type="gene ID" value="CP500_004195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018739">
        <property type="entry name" value="DUF2281"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10047">
        <property type="entry name" value="DUF2281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2281" evidence="1">
        <location>
            <begin position="100"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="14472" checksum="E4D35D118D6E52BC" modified="2018-01-31" version="1">MSKFQLFDAVSLTEEIALADGGVVPPETAGAIVEVFKNGEAYLVELFGGWVKAEVGGDFVPATQDQPESFMETIGVETVYPHQLQLVKSASEMMGLRSRLQSVLDNLSEDLVAEVCDFAEFLQEKQQKVRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4N9</accession>
    <name>A0A2G4F4N9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56681">
        <property type="protein sequence ID" value="PHX56681"/>
        <property type="gene ID" value="CP500_004090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="8404" checksum="77224E21FD07AF82" modified="2018-01-31" version="1">MRLDAIFIRFYKSFNVDHHRQSSATDNQPTNSEEANKNIKTLPWEIIKADGNDLWFPFIKVPIEPQIDDRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4S3</accession>
    <name>A0A2G4F4S3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56701">
        <property type="protein sequence ID" value="PHX56701"/>
        <property type="gene ID" value="CP500_004210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="157" mass="16407" checksum="9B20735593888713" modified="2018-01-31" version="1">MSVTPKDKGSAIARRGKAASKSEATVVSDANATGIQLYLPAGLPKRPVGPNDFTVSEIVSISGKRPIGTSTLHISETYGIVGNRPVEASELEVVATLGRRPIGASTMQVSEMFSMSGARPVAVSNLHIDEVYSTMGGNRPIASNDIDDSSTLMGFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4T5</accession>
    <name>A0A2G4F4T5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Disulfide bond formation protein DsbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56782">
        <property type="protein sequence ID" value="PHX56782"/>
        <property type="gene ID" value="CP500_003710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013834790" evidence="1">
        <location>
            <begin position="37"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="51"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="260" mass="28718" checksum="7D40347D2CC75C45" modified="2018-01-31" version="1">MNISSIWRKLRSQQAVGLSVLLAVCLIFIGCSPAQSAGGNPVDPKLKEQVLQIIRENPQAILESVQAYQQEKQQSLKAAQQSFLQEMKTNPKSSIGDSPNTGAASQQIVLLEFSDFQCPFCARAHDTVKQFMEKHQDKVTLAYKHFPLTSIHPQALPAAKAAWAAQQQGKFWEYYDALFEGQKQLGEELYGSLAQKLNLKVDKFNTDRNSPAAEAAIQKDVQLAQKLGIEGTPFFIMNGKTFSGAIELAEMETILASLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4W2</accession>
    <name>A0A2G4F4W2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56786">
        <property type="protein sequence ID" value="PHX56786"/>
        <property type="gene ID" value="CP500_003380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="13467" checksum="72EC5CDF01D8D675" modified="2018-01-31" version="1">MEPVEYQVILTAQARQLFSEIKDRREQQLLLARLEKLKQEPEKQGKALSEELTGYRSIRAVGQRYRIIYQIIQDRVLVVVVGIGRRKEGDRRDVYTVTMRLLVEMMQESDNDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Y8</accession>
    <name>A0A2G4F4Y8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">rplK</name>
        <name evidence="6" type="synonym">rpl11</name>
        <name evidence="11" type="ORF">CP500_002980</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6 8">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56854">
        <property type="protein sequence ID" value="PHX56854"/>
        <property type="gene ID" value="CP500_002980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0488">Methylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="10">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="9">
        <location>
            <begin position="71"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="141" mass="14764" checksum="8D28D24FD76CB34F" modified="2018-01-31" version="1">MAKKVVAVIKLAITAGKANPAPPIGPALGQHGVNIMMFCKEYNARTADQAGLVVPVEISVFEDRSFTFILKTPPASVLIQKAAGIAKGSGEPNRKQVGKITQAQLREIAEAKMPDLNANDVEAAMRIVAGTAKNMGVAIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Y9</accession>
    <name>A0A2G4F4Y9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56863">
        <property type="protein sequence ID" value="PHX56863"/>
        <property type="gene ID" value="CP500_003035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="19"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="180"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="348" mass="37330" checksum="302F0D87F5BCA133" modified="2018-01-31" version="1">MKVANKVHQILMRVPAPMYLGIAVLIFAASNSVTKKIVDIGQNHAINGRNPISLCNVLFVGNICALGLMTLIFYQDWKPHTLKALTRKDWISLTITGILSGAIAPALNFSALGQTNITNIVLIGRIEPILTLVLGVWLLGSRVNFWSIAGSLISLVGVVVTAFLASSGQMMTMAGFHIGTGEIFVAIAAIIGSIATIVGKLQLQSIPLGIFTIYRNILGTVIFFLLANLLYGPNHFAEVLSPFLWQWMIVYAAVIIITGQLCWLAGLKNATSTELNLASLLNPIAAIIMGYLILGESPTLAQYLGGSLLLVGIILGFVGNLHQAKINRELVNPSPREAMSMAIGFRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F502</accession>
    <name>A0A2G4F502_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF928 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56830">
        <property type="protein sequence ID" value="PHX56830"/>
        <property type="gene ID" value="CP500_003265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010328">
        <property type="entry name" value="DUF928"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06051">
        <property type="entry name" value="DUF928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="243" mass="27068" checksum="187CAEE6B8E6049A" modified="2018-01-31" version="1">MHPFHFKLAFGIGTILIGITPYSSWLQTSFSVLVTQNPEKPPDKDPPPGRRVRGGDLDPTNPNCKKTSQPLTAIVPANSLGTITSERLTLWFYVPYTSEDITSTEFSVLNRDETDYVYQTQFMMPKIPGIVSISLPLSAKNSLETGNFYRWYLKFKCKGSTSNAPDIETDGWVKRIASTPITTNQINTATPEIWYDAVNNLANRLLASPQDTKLKQEWTDLLKSVGLSNLAQEPLTGPVIISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F511</accession>
    <name>A0A2G4F511_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_003490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56801">
        <property type="protein sequence ID" value="PHX56801"/>
        <property type="gene ID" value="CP500_003490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="172"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="240" mass="26099" checksum="3760743A4FC7F24B" modified="2018-01-31" version="1">MSKIRVALIEDHDLTRVGIRTALQQSDTIEVVGDAANATDGLKLLQSSKPDVAIVDIGLPDFDGIELTQKFKKTIVADSDPDTKVLILTFQDNAQEVLAAFAAGADSYCMKDISFDQLLDVVKVTHEGNSWIDPAIARIVLKQARTKESAKEEPKSDGKKVTIKAAEPEFSHIIETYPLTGRELEVLELIVQGYSNAAIAEKLYITVGTVKTHVRNILNKLCADDRTQAAVLALRSGLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5C4</accession>
    <name>A0A2G4F5C4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF262 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56946">
        <property type="protein sequence ID" value="PHX56946"/>
        <property type="gene ID" value="CP500_002920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="50"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="21142" checksum="3939AA7E9125796F" modified="2018-01-31" version="1">MRSKLEQITLQDRNAAEMEIRDKRHQINYDTKQYPLEILVQKYMEGIDDDTNKLFIPDYQREMTWDEARQSKFIESVILGLPIPYLFVADIGDRENDESRLEMVDGAERILTLTRFVNNELTLSGLEKLEHLNGFKFADLLLPRQRNFNRTTLRVIELIKTPNQEFRRDLFERIQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5G1</accession>
    <name>A0A2G4F5G1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57024">
        <property type="protein sequence ID" value="PHX57024"/>
        <property type="gene ID" value="CP500_002215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020994">
        <property type="entry name" value="Uncharacterised_Ca-bd_CcbP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11535">
        <property type="entry name" value="Calci_bind_CcbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="214" mass="25074" checksum="358981B8D141A3DD" modified="2018-01-31" version="1">MSKFDKPKLKKPKFDNRLNKSKSLLSEAELPPIELDETIIAGRRPKPLNSLERLLMEIPEFNSIEPEMLTGRDGIIHFNIKEFDQKIAKILHSKSIDVGIENLVRYLAYLKKNLQLPCNVTGRQDFPWEEEYVIDSGNKKEYQKLKKSQPSYTDIFEIKQFKDSVYHDEGILVEVKRLSDHKEFVLPLVDLVTSDEDSQNNEFLDDYSTWFINH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5G3</accession>
    <name>A0A2G4F5G3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Addiction module toxin RelE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56717">
        <property type="protein sequence ID" value="PHX56717"/>
        <property type="gene ID" value="CP500_003640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="117" mass="13291" checksum="6E2D6EF9BAD5DED0" modified="2018-01-31" version="1">MKPLEWIASSKKDLKAMPDEVQDDVGYALLLAQLGEKHDDTKPLKGFKGAGILEIVDNFDGDTYRAIYTVRFESAVYVLHVFQKKSKSGIATPKQDIELIENRLKVAQEHHQTNYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5G5</accession>
    <name>A0A2G4F5G5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX57000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57000">
        <property type="protein sequence ID" value="PHX57000"/>
        <property type="gene ID" value="CP500_002630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="15513" checksum="C7DA926084CB4182" modified="2018-01-31" version="1">MTQSDRPTDAKTPCIINDRKLDYLFNVNIKPDAHNSKRAVQNRQQLNRLGFDDDSESRQFIQTHLEQAVQEESNIVERFINTYTNHTTGEEATIDTELRDSLLPGRTGKFAQVQSSWEVLPDGTRRFLSAIIYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5V0</accession>
    <name>A0A2G4F5V0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_001860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57164">
        <property type="protein sequence ID" value="PHX57164"/>
        <property type="gene ID" value="CP500_001860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040582">
        <property type="entry name" value="OB_MalK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17912">
        <property type="entry name" value="OB_MalK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="377" mass="42101" checksum="A42D99D34B82B0EF" modified="2018-01-31" version="1">MANVRLENITRRYQNVTAIENISFKIPDGEFWVLVGPSGCGKSTIMRTIAGLETATYGNIYIGDNLVNNIPARQRDVAMVFQNYALYPHMTVAENLAFGLRMRNVEQSQIQERVEIVARSLSIDHLLNRKPKQLSGGQQQRVALGRAIAREPKVFLLDEPLSNLDAQLRDDTRAELKLLHQRLGITTVYVTHDQVEAMTLADKIVVLNHGVIQQIGDPQSVYAKPVNRMVATFLGNPAMNILPAIYANESFQVGNQSLACPPSIQKKLQPREGQGFDLGIRPEHIELFTQSVTENDDFKSDVWALEKVPLEVEVKVVEPLGRETLIRASLPMLSPETTIQMQVAAGVRSRSGDRLSVQLDFDRLFVFDPSTGDALYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5X8</accession>
    <name>A0A2G4F5X8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lysozyme</fullName>
            <ecNumber evidence="1">3.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57101">
        <property type="protein sequence ID" value="PHX57101"/>
        <property type="gene ID" value="CP500_001945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002196">
        <property type="entry name" value="Glyco_hydro_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00959">
        <property type="entry name" value="Phage_lysozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="1" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="234" mass="26977" checksum="440CD4F4E0B8C43E" modified="2018-01-31" version="1">MTLLQAKKLQRQKMNLLRQSEIQIFGFLLVIGIVIGGAVFLAVNLRENLQFWHPASEMIKKPPLAMKAGDPYIRALMRTISASESNVSRPYHVVYGGKYVLDLSRHPDWCVKIVNGPNQGKCTTAAGRYQFLSSTWNEKAQRYHPKPVNFMMWQGYSFEPEYQDAVVYAWLRDRKFWKTDISQMLRQDKLTEVLRMLSGTWTSLGYGIENNSMSSSLPRVYKKMLEEELKNAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6M5</accession>
    <name>A0A2G4F6M5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_000465</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57443">
        <property type="protein sequence ID" value="PHX57443"/>
        <property type="gene ID" value="CP500_000465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018313">
        <property type="entry name" value="SBP_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01039">
        <property type="entry name" value="SBP_BACTERIAL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013585871" evidence="5">
        <location>
            <begin position="21"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="6">
        <location>
            <begin position="59"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="364" mass="39814" checksum="16734B68F5EFC8FA" modified="2018-01-31" version="1">MPKWRFLLLATMLTIAPLTACRDRSAQTPQTPQTGQTTATEGKSQQGPSRIDTIVSRGKLICGVSGQLPGFSFVDEKGKYSGLDVDVCRAIAAAIFDDPEKVEYRNLNAKERFTVLQAGEIDILSRNTTYTVSRDSTTGLEFAPTIFYDSQSVMVKKDSGINSLKDFAGKSICVQTGTSTEQNLSDQMRKLGVKYSPVVFEEVNATFAAYQEGRCQGVTADRSQLVSKRTTLPNSENNVILPEVMSKEPLTPAVKSGDAKWSDAVRWIIFAAIEAEDLGINSTNVDQIVASSTDPNIKRLLGKEGDLGKGLGLPNDYAARIVKKVGNYGEMYDRNIGPKSSLKLDRGQNKLWKDGGLMYSPPFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6P8</accession>
    <name>A0A2G4F6P8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FkbM family methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_000335</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57419">
        <property type="protein sequence ID" value="PHX57419"/>
        <property type="gene ID" value="CP500_000335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008107">
        <property type="term" value="F:galactoside 2-alpha-L-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002516">
        <property type="entry name" value="Glyco_trans_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01531">
        <property type="entry name" value="Glyco_transf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="6">
        <location>
            <begin position="26"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_21" evidence="6">
        <location>
            <begin position="255"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1561"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1595"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1629"/>
            <end position="1662"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1698"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1732"/>
            <end position="1765"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1003"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1505"/>
            <end position="1560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1765" mass="203410" checksum="25FF3E9881B4B8AE" modified="2018-01-31" version="1">MVIDLKGSGESQVISRFINAGNVVFDVGANAGDWTAEVLSQGHDLEIHLFEPIPHVYKKLVQNLDKQVISNNLAVGKKEEVKTFYYYEANPLLSTFYRRVDVEKQGLLNIPKEITVLTTTIDNYCQRHGIKRINFIKIDVGGAELDVLYGAKHFIETGRIDYIQFEYGGTYLDAKTSLKEASEYLQKFGYLIFKILPDNLEYKPTFLPEDENFQFSNFLAVNERFRQNVLGEALRMLDLQQIFTQYGIVPHGVIHVGAHEGTEIGTYQAMGVQKVLFVEANPVVFERLQANIAGVPNVQAVNCAVSNENGTVNLRVTSIDQSSSILQLKRHLELYPNIQETHQVEVQSRTIDTLLQELQLNSYDFNILNIDIQGAELLALEGAANWLKYVAAINTEVNYEELYDGCALIDQLDEFLEKHGFQRVATITHHPYWGDALYIKKPLITMAAFAIARFGNQIFDYAFLKMYTKEHGMRLELPAWSGQYLFGHNEPPISHPLPQVVEQETPYKLSESAILNAPEPFKNVDFIGYFQFHTQYYAQHKEYFLSLFKPLSEVEAKMQESVNRLRERGKTVVGLHLRRGDYSWASDIVPYLSIAPSEWYREWLDGLWETLDEPVLFIASDEIENVVGDFADYNPLTVKDLGVEMPEAPFYPDFYILSQCDVLATSNSTFSFAAAMLNERCKFFFRPNLQKNKLIPFDPWNSEPLLRENPSQKQTFYPQQEIICNKCKLSVCAILKNEAPYLIEWLEFHKIVGVERFYLYNNSTDNPFDIVKPYIESGEVIWHEWSLIPGQLQAYEHCLETYRQASEWIAFIDMDEFLFPTEKDDIKEVLEEFYDSPAVAVNWLVFGSSSHKTRPEGLQVENFTKRGLDDWEINKHIKSIVRPVEAIRPDSPHDFRYLNDRVATTENKEPIVGPWSTVNSVQKLRINHYMTRSLQESQEKMLRGKADTLDPRPWMFDLSDRNEVEDLTIQRFVLKLREAVDKIISPSPMTQILTEQSRLQSKLYEMQIQLEEFQTELDDTQKKLALSESQLHQTEQQLKESNYRVQQFDVDLQKIPKIQESNSLQRKILAVVDVAPAYPEALEWLRGFNLDSPTVGKVDNNEILFSGWVLGKSERSVAVEFIYNDETVLTIPVNGYRSDLVSAYPELPLAANSAYEARLKIGVQQPESEVVIQAVLANNETRVKLGVVRLQEVVYHFPLGNQKQKYRMKWFFAINEASPGFEIYSQMIKVAVYTALQNTSLEPYCIYDGEENELTDWLQKNGVKIIYHRTPHYEKLQTQHPLYSTVAFGAFLRIEIPKIVEIYEIPDEYVFYTDCDVMFFDDVVDYLQGITCEYLAATPEHDPNNWEYFNSGVLYMNVKNLQKIQKEFDDYIDQNLDQILPLAFDQGAYNLFFKDKWDRLDIQLNWKSYWNFSPEAKIIHFHGPKPTQAEDIRKKTAPASSMLFANGFYWLNTGIWQFIYEKIEELDAGILVKPTECEQTDPQLEDTRKELEESQTKLHQNPGGFEQFTTKLQQVQEELQPIKEELEIRQIQYQKTQEELEQTKSQLNEVKTQLQEMESAAAPLNQLAESYLAQGKLEEAIAVCEQSLKIQPKFAPAYKTLGNVFQAQGKLDEAESYYLRALEIQPDFAQALANLGTIHAQQQQWQEAIACYQKAIAIQPNFPGVYRNLAKVFSQVGKPDEAVECCYAAAILEPKTTAEEYFNLGNTLLEQGKQERAIVCYRRAVELNPDEVEVYYKLGETLAKVGQLEEAISAYRRAIELTSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F716</accession>
    <name>A0A2G4F716_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Adenylate kinase</fullName>
            <shortName evidence="4">AK</shortName>
            <ecNumber evidence="4 6">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">adk</name>
        <name evidence="7" type="ORF">CP500_000200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="4 6"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57397">
        <property type="protein sequence ID" value="PHX57397"/>
        <property type="gene ID" value="CP500_000200"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMP" evidence="4">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="184" mass="20877" checksum="E2ED7A12DEC43318" modified="2018-01-31" version="1">MRLVILGGPGAGKGTQAQLLCSDLSIPLLAVGDILRGAIASETDLGKLAMPYVETGELVPDAAMIQFFRQRLLLWDVFNGWVLEGYPRTAFQAEELDFLLDDLAQQLDWAIWLKVPTEVLLSRSIERDRSDDSPEILQRRLDLYHEQTIPILDYYEHRNKLLIINGDQPPEKVQQDILKIVNSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUA8</accession>
    <name>A0A2G4EUA8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metK</name>
        <name evidence="17" type="ORF">CP500_023140</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000269">
        <property type="protein sequence ID" value="PHX53133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53133">
        <property type="protein sequence ID" value="PHX53133"/>
        <property type="gene ID" value="CP500_023140"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10 11 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="5"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="126"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="254"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Flexible loop" evidence="11">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="175"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="251"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="266"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX53133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="420" mass="45299" checksum="9464D520574B6E51" modified="2018-01-31" version="1">MSRHYLFTSESVTEGHPDKICDQISDTILDALLTEDPKSRVAAEVVVNTGLMLLTGEITTKAQVNYIELARKKIADIGYIHADNGFSANSCSVLVALDTQSPDIAQGVNTAHESREQSSEEELDAIGAGDQGLMFGFACNETPELMPLPISLAHRICRQLAAVRKTGQLPYLRPDGKSQVTVVYEDGKPVGIDTILISTQHTEAIGDIVDTAAVQAKIKEDLWTAVVEPVFADIAIKPDAETRFLVNPTGKFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDPTKVDRSAAYACRYVAKNIVAAGLAEKCEVQLSYAIGVARPVSMMIETFGTGKVDDDRLLEVVKQLFELRPAGIIQAFNLQNLPAERGGRFYQDVAAYGHFGRTDLELPWEQTDKVELLKSALSQQLSAVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUI8</accession>
    <name>A0A2G4EUI8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HU family DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_022750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000244">
        <property type="protein sequence ID" value="PHX53203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53203">
        <property type="protein sequence ID" value="PHX53203"/>
        <property type="gene ID" value="CP500_022750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="100" mass="10632" checksum="001BA6A2CA28D2DC" modified="2018-01-31" version="1">MNKGELVDAVAEKATVTKKQADAVLSAALEAIMEAVSDGDKVTLVGFGSFESRERKAREGRNPKTGAKMEIPATRVPAFSAGKLFKDRVAPDKNADKAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUP3</accession>
    <name>A0A2G4EUP3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000229">
        <property type="protein sequence ID" value="PHX53251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53251">
        <property type="protein sequence ID" value="PHX53251"/>
        <property type="gene ID" value="CP500_022480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="6941" checksum="2B80D20EB3CE678F" modified="2018-01-31" version="1">MGSNWLFECSHQRADFCTEIDPQALGYRQYPSLSSADRTYSNPKSFVNFLLPPLSKGRVGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUV2</accession>
    <name>A0A2G4EUV2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Prepilin leader peptidase/N-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
            <ecNumber evidence="10">3.4.23.43</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_022200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine.</text>
            <dbReference type="EC" id="3.4.23.43"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase A24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EC" id="3.4.23.43" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000218">
        <property type="protein sequence ID" value="PHX53311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53311">
        <property type="protein sequence ID" value="PHX53311"/>
        <property type="gene ID" value="CP500_022200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010627">
        <property type="entry name" value="Pept_A24A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014032">
        <property type="entry name" value="Peptidase_A24A_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06750">
        <property type="entry name" value="DiS_P_DiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00864">
        <property type="entry name" value="PREPILNPTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="DiS_P_DiS" evidence="13">
        <location>
            <begin position="15"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="12">
        <location>
            <begin position="109"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX53311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="275" mass="29969" checksum="E76FA208068B8C16" modified="2018-01-31" version="1">MELIFNCLVYTIIFVVGSAIGSFLNVVVYRLPAGLSMIHPPSRCPKCLNQLKSYENVPVFGWLWLRGRCKNCRCRISVRYPLVEAAMGLLFLLIFWQFGFTVQTLGFWAFFSWLLALSLIDCDTMTLPNSLTRSGLVLGLVFQVAKGWWPIFSATGSVNYLVLDGILGAVVGLWLFDIIGFAGSIAFGQNAMGAGDTKLAALMGAWLGWKYLLLAGFIACLAGAVAGGGAIAIGLLDRRQPMPFGPFLALGAAITALWGEAILSTYWQLFFPNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUW3</accession>
    <name>A0A2G4EUW3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_022005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53329">
        <property type="protein sequence ID" value="PHX53329"/>
        <property type="gene ID" value="CP500_022005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="264" mass="29506" checksum="7C951121A737C4D0" modified="2018-01-31" version="1">MSDERLQKILAQWGIASRRQAEEMIVAGRVRVNGNIVNLGQKANPDLDRIEVDGLPVIATERPQLVYLLLHKPAGVLSTCSDPRSRSKVLDLLPPKLRYGQGIHPVGRLDADSTGALLLTNDGKLTFCLTHPRHSISKTYQVWVQGHPPESVVQVWRDGIILSGRKTMPAQVKILDRTRDQTMLEVILSEGRNRQIRRTAEQLGYPVVRLHRTAIGSIQLQPPSEPILPVGCCRTLTDSEIIFLWTLVNLTSINVPVKIRKHSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV43</accession>
    <name>A0A2G4EV43_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53401">
        <property type="protein sequence ID" value="PHX53401"/>
        <property type="gene ID" value="CP500_021650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="8748" checksum="0E6FC936812AB19A" modified="2018-01-31" version="1">MPASVLHLFDRITVNPRQCGDRPCIRGMRIRVIDILELLAAGLSFEQIIEELPDLEVDDIKAALLYAVRKLDHPVLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV92</accession>
    <name>A0A2G4EV92_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53445">
        <property type="protein sequence ID" value="PHX53445"/>
        <property type="gene ID" value="CP500_021525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019574">
        <property type="entry name" value="Periplasmic_polyamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013747274" evidence="2">
        <location>
            <begin position="20"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR019574-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="353" mass="39457" checksum="7B87583A36EFFBA8" modified="2018-01-31" version="1">MKRLLTLFLLFLISAMVPFGCSSTGAKQQQVLSIYNYASYIAPDAIAQFEKENNVKIQYDTFENSDALYAKLKQGNPGYDLIFPADYMVKIMVKEDLIEPLNINNIPNHKNLDPKYINQAFDPGNKCSLPYQWGTMGIGYNLKVTKGEINSWASMFDSKYAGKIAWQDDARYTFAGVLIYLGFDPNTTNPEEINKARDLLIKNKNIIAAFVPDTGQTLLDQGEVNLTMEWSGDIFQVMKENPNLGYAIPKEGTIIFSDNMAIPKGAVHKELAEKFINFVLVPEVGAKISNFTHFGTPNKLAIETGLIDPQDLKNPQIYPADQAFAKMKFLQDVGNATALYDRAWTEVKASAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVD5</accession>
    <name>A0A2G4EVD5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000199">
        <property type="protein sequence ID" value="PHX53426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53426">
        <property type="protein sequence ID" value="PHX53426"/>
        <property type="gene ID" value="CP500_021555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="520" mass="56381" checksum="960E0930BE8C38F1" modified="2018-01-31" version="1">MDAEELQAKYAAGERDFTAILLCEANLSRIDLSGANFTEAILSLTNLSGANLSGANMRKAKLNVARLSGANLHKTNFSGAILNVANLIRADLREAQLVEATLIRAELIRANLSIANLSGANLSEADLREATLREANLEQADLSGAHLRGACLTAANLERANLHRADLSRADLRGVNLCNAELRQANLSQANLSGADLRGANLRWADLSGTNLTGADLGEARLSGANLYGANLSNANLLNATLVHADLTQANLIHADWVGADLTGAALTGAKIYAVSRFGLKADDITCDWVDLSPNGDRSNIQRFSAEKAQKYFNATPPTVQIIVDHPLDPNANFILAATYRQIALQYPGLSHPPSIEVNSRRTIISFRIEQDEQLFPTAFVAIIPFSDAAFTQKNLITMLKMIQPQPGNNLGVRVSNLVAQLSVAMTQTIRKIREIKIQPIPLDRETVSTFFQSPTQTLLSNSSAESLMVHYHPDFGKHLINLPRVTKNSINPAIKAQRLTTPPINTVIEFIKGFYQLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVG2</accession>
    <name>A0A2G4EVG2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsJ</name>
        <name evidence="4" type="synonym">rps10</name>
        <name evidence="6" type="ORF">CP500_021065</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000184">
        <property type="protein sequence ID" value="PHX53523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015174046.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000184.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53523">
        <property type="protein sequence ID" value="PHX53523"/>
        <property type="gene ID" value="CP500_021065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="10"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="11992" checksum="8B11285F60AD5DD5" modified="2018-01-31" version="1">MAAIQQQKIRIRLKAFDRRILDASCEKIVDTANRTAATAIGPIPLPTKRRIYCLLRSPHVDKDSREHFETRTHRRIIDIHQPSAKTIDALMKLDLPAGVDIEVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVJ5</accession>
    <name>A0A2G4EVJ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000178">
        <property type="protein sequence ID" value="PHX53555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53555">
        <property type="protein sequence ID" value="PHX53555"/>
        <property type="gene ID" value="CP500_020860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8223" checksum="B0392B8BBD93753B" modified="2018-01-31" version="1">MILPLSMSWEQFKALDSLLEYTRSVRWFYLDGYIDHNSVDTVLTCQDSIYESCILRFLMSIVEQASCLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVL4</accession>
    <name>A0A2G4EVL4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53575">
        <property type="protein sequence ID" value="PHX53575"/>
        <property type="gene ID" value="CP500_020755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="164"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="455" mass="51998" checksum="1C1911168563218E" modified="2018-01-31" version="1">MNVEDVVEWANNSIFDKTGEHLTPIQEAILTGVWQRQKYPQIAKDFHCSESHVKKEAAKLWENLRKELGKDLNKFNFRSKIEKKYNLPNISHLHDSLLQIDNVICGQFIQNIKNAEARSPFPPDSPQNKSQFPIIDLTDAPELTSFYDRTSELSTLKEWILQAHTRLITIYGLSGIGKSALTLKLIEQTQTEFDYIIWLSLTNTPTLSTLQTELKQFFGRSQQNPLPTIIDYFRASRCLVILDDVHNIFKPSELVSQYLTGYEDYSKFFKQIVTSSHQSCLILLSWEKPREITALEAENRATRTLHLKGLGEEAAEILREKGLADEEKWSDLITLYQGHPSWLNIIAATIWELFDGSVSLFLADGNDVFLGDLEPILESHLERLSDSEKKVCYLLATQAEAVDISQQPADSELSKSEFLQAIQSLSRRGLVEKMQVGVRSNFQIDPVFKAYIQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVP5</accession>
    <name>A0A2G4EVP5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sugar transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000174">
        <property type="protein sequence ID" value="PHX53604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53604">
        <property type="protein sequence ID" value="PHX53604"/>
        <property type="gene ID" value="CP500_020635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="340" mass="39584" checksum="E2D6260DA761A503" modified="2018-01-31" version="1">MTNGIYILANDVVFDHLVALLNSLEVNGAKDIPVCIIPYDDRMKKIQVEIATRPSVTLFDNTDSIDFWEDFATQAWTSHAKAQKLWQAKGWKPVHCLGMHRKFCCFDGPFDKFVYFDADTLLMGSLDYIYQKLDDFDLVANDFQYLSNLNYVFDLSSEKLQHIFNIDQLQSRIFCAGWFASKTSILNRNNSAKLLRKLTSGESEILSFRGTDQPLFNYLVPRSKISFYNFAYAQPEQVTGNHWSSQFDVIDDVLYDKGRRLTYLHYMSISATKINQLCAGEDVEIPYRDVFLHYRYLKSPEKCPKLKSPSWLVQLGRNLKSWGIQKVNNVQFKLRNFWDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW15</accession>
    <name>A0A2G4EW15_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TIGR00300 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53714">
        <property type="protein sequence ID" value="PHX53714"/>
        <property type="gene ID" value="CP500_019960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12144">
        <property type="entry name" value="SDH_N_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005239">
        <property type="entry name" value="CHP00300"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007545">
        <property type="entry name" value="LOR/SDH_bifunc_enz_cons_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04455">
        <property type="entry name" value="Saccharop_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00300">
        <property type="entry name" value="TIGR00300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharop_dh_N" evidence="1">
        <location>
            <begin position="286"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="704" mass="77950" checksum="B67CD0AE0D13E6AA" modified="2018-01-31" version="1">MTDSIRFLMCAPDHYDVDYVINPWMEGNVHKSSRDRAVEQWEKLYHVLKENAIVDLVPPQKGWPDMVFTANAGLLLGNTFVLSRFYHKERQGEEPYFKEWFEDKGFTVHELPKDLPFEGAGDALLDREGRWLWAGYGFRSELDSHPLLANWLNIEVLSLRLVDERFYHLDTCFCPLSGGYLLYYPAAFDSYSNRLIEMRVAPEKRIAIEEADAANFACNAVNINNIVVMNKVSDSLKTRITNAGFKVIETPMSEFLKAGGACKCLTLRVIEPVQEDRSANVMVESRAIRMEGHLLDAGLISRALDLIVENGGSFQVLNFSLGEQRQSTSTAEVKVSAPSHDVMEDIIALLIDLGAVSPPQELCDAILEPVVQDGVGPDDFYVSTIYPTEVRVNNQWVKAQNQRMDGAVAITETAEGPVATCKLLRDLKVGEKVVVDVVGIRTIRKTESREQRNSQEFSFMSGSVSSERRVELVVEQVAWELRQIRDRGGKVVVTAGPVVIHTGGGEHLAHLIREGYVQALLGGNAIAVHDMEQSNMGTSLGVDMKRGIAVRGGHRHHLKIINTVRRYGSIAKAVEAGLVTNGVMYECVKNNIPFSLAGSIRDDGPLPDTQMDLVKAQEEYTELLRGADMVLMLSSMLHSIGVGNMTPAGVKMVCVDINPAVVTKLSDRGSIESTGVVTDVGLFLSLLVNQLDKLTSRHHVTQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW47</accession>
    <name>A0A2G4EW47_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cofactor assembly of complex C subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53755">
        <property type="protein sequence ID" value="PHX53755"/>
        <property type="gene ID" value="CP500_019775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021919">
        <property type="entry name" value="CCB1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35302">
        <property type="entry name" value="PTHR35302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12046">
        <property type="entry name" value="CCB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="19480" checksum="56D883D38160E089" modified="2018-01-31" version="1">MNTAVLPSTFVLTLLLAVGLFFFIKASVKDRIEQVKLSSESAQESLLTELQEYFAQRAYRVAAVDAPNYKVTFEGFVRPSWFLAIFLTLLSAGGALCLGLVLAMLVPQQGQIFLALVLLSPLTGIFYWKKAGRPEQVSLKLESVAESGNQTKSLVTVRGHRDELAAMQKALDLKLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWE8</accession>
    <name>A0A2G4EWE8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000147">
        <property type="protein sequence ID" value="PHX53865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53865">
        <property type="protein sequence ID" value="PHX53865"/>
        <property type="gene ID" value="CP500_019195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="43084" checksum="0D43EF497B520971" modified="2018-01-31" version="1">MLILPKYERQIDWSFSYINQPINSEWATIVSGDRKKVTLVDRNFSPKYEYQLPDEISCLAINPKGDLLAAIMANGNHLAILTAENQLVFEEQLPNPPVKYFNKNGFEDCWFDADGVRFWCIKLIEGEEVEIQIRDTNSWHIQRKIRLKDPFYGRGFLFQRHPENQILAVWTTEGQGESQIYWLYDDGMTIHAVEVLCADDYMGPPEFHPAGGEFLIVHDCGRKISRFSFPDRNLLGICEWPWPGLSDGFGSYMCYLSDDRILVNTDEGLMYLIDINKMEISEELILIGHEPRSYKELFPNLKDLKEQLCGDLKYFYRFDSDSILSVHSQVLSQQPDSKQKTLVIFGGKELFGSLATVQQSAPYSKLFIQSLGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWI1</accession>
    <name>A0A2G4EWI1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000145">
        <property type="protein sequence ID" value="PHX53879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53879">
        <property type="protein sequence ID" value="PHX53879"/>
        <property type="gene ID" value="CP500_019130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="59" mass="6196" checksum="7186BCE0CC8A77A3" modified="2018-01-31" version="1">MKYSILVLGVFDLGSASVTALAPQAKFATTHGAVESCPDFQYTGTNEDGEQEEVQTGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWI5</accession>
    <name>A0A2G4EWI5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gap</name>
        <name evidence="10" type="ORF">CP500_019010</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53905">
        <property type="protein sequence ID" value="PHX53905"/>
        <property type="gene ID" value="CP500_019010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="2"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="154"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="213"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="11"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="339" mass="37031" checksum="15B23983261AF447" modified="2018-01-31" version="1">MIRVAINGFGRIGRSFTRCLLGRENSQLELVAINDTSDPKSNAHLLKYDSMMGTLKGVDITTDENSITLNGKTVKCVSDRNPLNLPWKEWGVDLVIESTGVFIDQAGASKHITAGAKKVLITAPGKGPEVGTYVMGVNHHDYKHSDYTVISNASCTTNCLAPVLKVLHENFGIIKGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAQAVALVIPELKGRLNGIAMRVPTPNVSVVDFVAQVEKKTFTEQVNQVFKEAAEGSMKGILEYNDLPLVSSDYRGNDSSSILDSSLTLVMDGDMVKVLAWYDNEWGYSQRVVDLAELVAQRWEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWJ3</accession>
    <name>A0A2G4EWJ3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">GDP-mannose 4,6-dehydratase</fullName>
            <ecNumber evidence="3 4">4.2.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GDP-D-mannose dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gmd</name>
        <name evidence="6" type="ORF">CP500_019005</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H2O</text>
            <dbReference type="Rhea" id="RHEA:23820"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="EC" id="4.2.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="3 4"/>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53904">
        <property type="protein sequence ID" value="PHX53904"/>
        <property type="gene ID" value="CP500_019005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019673">
        <property type="term" value="P:GDP-mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="PTHR43715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="5">
        <location>
            <begin position="5"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="318" mass="35100" checksum="8B6F1E0AC0D986D9" modified="2018-01-31" version="1">MKKALICGISGQDGAYLAKLLLDKGYAVSGTSRDAQMSSFGNLTRLGIRDQVKLESMSLNDFRSVLQVLAKIGPDEVYNLAGQSSVGLSFEQPVETLESIATGTLNLLEAIRFTGGKIKLYNASSSECFGDTGGNRADENTPFRPRSPYAVAKAAAFWEVANYREAYHLFACSGILFNHESPLRPERFVTQKIVSVVCRIAAGSSEKLHLGNISVHRDWGWAPEYVEAMYLMLQQDEPEDYVIATGASFALEEFVQTAFVCAGLDWREHLVTDASLYRPTEIAVGKGNPAKAKAKLGWEAKYKMQDVVRMMVEARRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWR4</accession>
    <name>A0A2G4EWR4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="4 11">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">murC</name>
        <name evidence="16" type="ORF">CP500_019020</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="4 11"/>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53906">
        <property type="protein sequence ID" value="PHX53906"/>
        <property type="gene ID" value="CP500_019020"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase" evidence="13">
        <location>
            <begin position="12"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="15">
        <location>
            <begin position="165"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="14">
        <location>
            <begin position="360"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="167"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX53906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="518" mass="55531" checksum="2EE613C07567526E" modified="2018-01-31" version="1">MPSSVDFTGKPFHFIGIGGIGMSALAYILAKRNLPVYGSDIKSSHITQRLQAMGAHIFWGQNASNFELFQRSALDHSPAGQSPEKAVPSAGESRVGGSVAIAQAVKQNSSDQAAKSVLGLPQVVCSTAIHQGNAEYRAALDLGCPMFHRSDVLAALIQDYQSVAVAGTHGKTTTSSLIGFMLMTAGLDPTIVVGGEVNAWEGNARLGKGPYLVAEADESDGSLVKLVAKIGVVTNVELDHPDHYNTLDQVIDIFKVFAQNCQTLVGCIDDEIVKDCLKPSISYSLQPDSGADYTADQVLYGADSTKARIWERGVVLGEMELKLLGKHNLSNALAAIAVGRLLGVEFSAIVSAMASFEGARRRFEVRGFHNDILFVDDYAHHPSEIHVTLAAAQLRIKGSEKNSKSGRVVAIFQPHRYSRTLTFLPEFAQSFGDADLVVVCDIYSAGEPDLGQISGQKVADLIAKEGRKVEFQASLESVSKFLTQNLQPGDLALFLGAGNLNQIIPEVMAVYQSVDRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWV3</accession>
    <name>A0A2G4EWV3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53920">
        <property type="protein sequence ID" value="PHX53920"/>
        <property type="gene ID" value="CP500_018855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="8022" checksum="11B0B66BF96ECBBA" modified="2018-01-31" version="1">MNSKDVAQYIEATDGISKPWLLVQLRLKKLQERRSDISAEEYLTQLTDIHQDLMNLGEWWLGIEDEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX29</accession>
    <name>A0A2G4EX29_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000133">
        <property type="protein sequence ID" value="PHX54000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54000">
        <property type="protein sequence ID" value="PHX54000"/>
        <property type="gene ID" value="CP500_018515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031009">
        <property type="entry name" value="Tcm_partner"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04474">
        <property type="entry name" value="tcm_partner"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="375" mass="42890" checksum="B665F4793FB6993F" modified="2018-01-31" version="1">MADNSFFDESTDNSLVKSEIVAKYFWAWAKVIIPRAKKRSNKIGYIDFFSGPGSYQDGSKSTPLLILERAIANPDMSEMLVTLFNDKDSNNTRSLQQAIASIPDINRLRHEPIVLNKEVGEEIFQAIQEINNNVPTLYFIDPWGYKGLSLKLIDSIIKGWGCDCIFFFNYNRINMGLPNVAVDKHMNSLFGQERANALREQLKLKQPYERELVIVEAISQALKEIGGNYVLPFRFKTDTGTRTSHHLIFVSKHERGYSIMKDIMAKESSSTEQGVPLFEYNSATQNQPLLFELSRPLDDLENMLSNEFAGQILTMEAIYNQHHVGKRYISKNYKEALRKLEQQGKIIVDPPASKRKKYKGEITFGEQVKVTFLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX34</accession>
    <name>A0A2G4EX34_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53707">
        <property type="protein sequence ID" value="PHX53707"/>
        <property type="gene ID" value="CP500_020110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="13017" checksum="2C12C1AF5B53AD6C" modified="2018-01-31" version="1">MKSTLCFPETSLKSHQVNSDTNAVHSQSNMEYCIAAAWIDLVGGDYSSFEGDDWLAISGDIDEGEIYREWFLWQDSEVTQEWEAYDPITNYRIVASSRALLIAKIDQIEDTRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXE0</accession>
    <name>A0A2G4EXE0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54203">
        <property type="protein sequence ID" value="PHX54203"/>
        <property type="gene ID" value="CP500_017405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025569">
        <property type="entry name" value="DUF4335"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14233">
        <property type="entry name" value="DUF4335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="281" mass="30048" checksum="77BDD0AA2C8693E6" modified="2018-01-31" version="1" fragment="single">MVLKRYTPPTCTLEITAKSSPLSRWAHKPVLKSLTFELRLDDPRLPDTEHVTLNGDRTQLEALHEAVNSYIQNLLGESRPWETRSQSEFSDSVAKTASTPTRSPVMLHESFNPSEKATSELNSSDSPKNANFPAPPHLESRGLLAHNLFLGSLTVAESSPVVRLSTVQLFDLATALDEYSSEVMALPNLSRSPKRSQPVPWLKVAAMVVASLGLTTGAIKMLQVRQAQIASAPTSAASSPSAQPNLAIGVSPSPSLTTPTSPAPTPSATPTLPPLPPPPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXR8</accession>
    <name>A0A2G4EXR8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54334">
        <property type="protein sequence ID" value="PHX54334"/>
        <property type="gene ID" value="CP500_016595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8124" checksum="855401158CC47B5B" modified="2018-01-31" version="1">MGIGHWALGIGNRALGIGHRALGIGHWVIGNSQQSTVNCQQSTVNSQLTLFHCHRLSQIPRLIHIQTPSCGNMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY15</accession>
    <name>A0A2G4EY15_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000128">
        <property type="protein sequence ID" value="PHX54057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54057">
        <property type="protein sequence ID" value="PHX54057"/>
        <property type="gene ID" value="CP500_018130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="61"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="184" mass="20436" checksum="10732173D80A8D5C" modified="2018-01-31" version="1">MLKLYGGARSRASIVKWYLEEIGVPYEFVTLDMQAGAHLQPDFLEINPIGKVPAIADGDFKLWESGAILLYLAQKHGKMPETLEQQAQVVQWVMFANATLSPGIFAEATRDRETPKLLTPLNQIFEKQSFLMGDEFGVADVAVGSILSYIPMMLKLDLSAYPAVLDYIKRIAERPAFQKAIGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY35</accession>
    <name>A0A2G4EY35_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54077">
        <property type="protein sequence ID" value="PHX54077"/>
        <property type="gene ID" value="CP500_018110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029471">
        <property type="entry name" value="HNH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025938">
        <property type="entry name" value="RRXRR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14279">
        <property type="entry name" value="HNH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14239">
        <property type="entry name" value="RRXRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="186"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="429" mass="48920" checksum="F670BB9D1B7CA712" modified="2018-01-31" version="1">MSKNPNQVFVLDSRKKPLTPCLPVIARKLLNAGKAKVFRLYPFAIILNKSVEEQPQPIEIRIDPGSKTTGIALVFLTQVIWGAELTHRGQAIKSRLETRRAIRRNRRNRKTRYRQPRFFNRIRRKGWLPPSLQHRVLTTITWVNRLCKLAPIKSIAFELVKFDTQKMQSPEVYGIEYQQGELQGYEVREYLLEKWNRKCAYCSAENLPLQVEHMNPRAKGGSNRVSNLCLACKKCNIKKGTEDIKDFLKSQPDLLKRIMSQAKASLKDAAAVNATKSALLEVLKATKLEHIYVGRGSLTKFNRTKLGLPKANWIDAACCGDVSQGLTLAINQPLLIKAMGWGSRQVVQTDKYGFPRKGYQPKKKVKGWKTGDIVSVIDGKYEGVKCKRIKTTRFKGNFDIRVNDTTVISVSRNQIKPVQRNDGYNYSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYA5</accession>
    <name>A0A2G4EYA5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Molybdopterin synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54440">
        <property type="protein sequence ID" value="PHX54440"/>
        <property type="gene ID" value="CP500_016035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="SSF54690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="17708" checksum="AC24A4FBC4222091" modified="2018-01-31" version="1">MNSGAALSLDTVPQRNALDSFAITFAPLSLEEIYTLADDAANGAVVLMSGTVRNQTEGQAVVALEYQAYEPMAVRVFQQIATEIRRQWPDVNRVVIHHRVGRLQVGEISVLVAVGCPHRDSAFAACQYGIDTLKHNVPIWKKEHWADGSSSWVNIGACEVSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYD2</accession>
    <name>A0A2G4EYD2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54545">
        <property type="protein sequence ID" value="PHX54545"/>
        <property type="gene ID" value="CP500_015605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025478">
        <property type="entry name" value="COP23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14218">
        <property type="entry name" value="COP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013901986" evidence="1">
        <location>
            <begin position="29"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="153" mass="16634" checksum="C8B88ADBE94793FE" modified="2018-01-31" version="1">MKFRLLKSVFTASIMAIAPMIANSPAFAQTTSFFCGAAGSHPATIADQQGKNIPVILWVTDNYFNESGEDAMTRCTRVSGILNNSQSQGNWDNIITAGASRTGQPIICAANPQDGSCRLLYQIPRGQNPEQARQELLRRIKNPNLSIPPVKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYE9</accession>
    <name>A0A2G4EYE9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54549">
        <property type="protein sequence ID" value="PHX54549"/>
        <property type="gene ID" value="CP500_015460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="15263" checksum="D676E9B5B21F7561" modified="2018-01-31" version="1">MASQKASKIDLNGDYPCPCRRRGRLVPIILTEAFGCNRCQQIFVLDESGYVIEQLSTNYPYKQTWRWTGQQWNRAHGGLRNHYLPLALGMILVPLMIWLPLALHSPGANVILWAMIAVLLAMLPALMVLLAYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYL6</accession>
    <name>A0A2G4EYL6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000090">
        <property type="protein sequence ID" value="PHX54586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54586">
        <property type="protein sequence ID" value="PHX54586"/>
        <property type="gene ID" value="CP500_015350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="299" mass="34251" checksum="F95B92FF723A5FF4" modified="2018-01-31" version="1">MRFINPKTDFAFKKIFGSNESKPILISFLNAMIYRGNSTITDLENIDPYLEVQYLKDSYLDVKARLAGGATVIIEMQVLNIESLAKRVVYNTAKAYSTQLFSGQGYSKLKPVIALTITDFEMFDNDQEVISNFVFKEKERLFDYVDPGMEMIFIELPKFNKKMDELETLTDKWIYFMKNAYTLEIVPSTMENVSEIQQAFAIANEANFNPKELADLENRERYILDQQGIFVQGIKEGVAQGREQAREKGRKKGREEGIALGIREKALEIARQLLNVLDNQTISQTTGLSVEDIQNLRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYN8</accession>
    <name>A0A2G4EYN8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54600">
        <property type="protein sequence ID" value="PHX54600"/>
        <property type="gene ID" value="CP500_015285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="12"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="437" mass="49077" checksum="005FF90D2EE6C9AF" modified="2018-01-31" version="1">MTSFPSPNQNQVVIRPFQHRDIEVMEQLCAETTDEAENPKGASPDLVFTSKLQQLRRWYGLLKILSLFPNPYQSLFRAHVAEEEGIVKGVIQISPFNRTRSTWRIDRIGVDSEARSKGIGSMLLRHCFEAVWEARTWLLEVNVGDTSALALYRQNGFQPLAQMTYWTIAPERLQEMACATPDLPNLLPVSNADAQLLYQLDTASMPPHVRQVFDRHIQDFKTSFLGALIEGVRQWLGKTEVVSAYVFEPQRKAAIGYFQVQLSRSGNEPHVAQLTVHPAYTWLYPELLSQMARLVQDFPVQSLNLASADYQPEREAYLEQFGAVRVEHSLLMSRSVWHKLRESKLVSLEGLQLSEMLQGFQPTRKPVPGRMSWLGPIAPEAATTPPSSEVKPLLADTGNNQANQVNPLNSQISESTATDDASILPLKLSDLPIDGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYS2</accession>
    <name>A0A2G4EYS2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system VapC family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54618">
        <property type="protein sequence ID" value="PHX54618"/>
        <property type="gene ID" value="CP500_015175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09872">
        <property type="entry name" value="PIN_Sll0205-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041705">
        <property type="entry name" value="PIN_Sll0205"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="14436" checksum="171DA88A6DC11A2E" modified="2018-01-31" version="1">MKLLLDTHIWLWYLLGDPRLSRSLQTAIADSNTELWLSPISIWETLILAEKGRISLQPDPVTWVNLALKTLETREAQMNHSIAILSREIALPHQDPADRFISATAIYYGLILATVDANLTGNSALQTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYS5</accession>
    <name>A0A2G4EYS5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polyamine ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54672">
        <property type="protein sequence ID" value="PHX54672"/>
        <property type="gene ID" value="CP500_014850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="367" mass="41428" checksum="1ECB5ED3102A14A8" modified="2018-01-31" version="1">MKRRSLLLGTATLTLTQLAAGCDSKPSLKIRSLKNAIPAQLVSKFSRDSKPSSVLQVTQSAQLTELFTLLQDWKRLPQSKNQADLVMLGDYWLTLAIRQKLIKPIDPKKISNWSKLPERWRTLVRRNDDGQLDPKGKIWATPYRWGNTVIAYRTDKFKALGWTPTDWSDLWRDELRDRISLPNNAREVIGLTLKKLGKSYNTQQLDQVPNLKAELTKLNQQVKLYSSDAYLQPLILGDTWLAVGSSADVLPLLQTQKDIAVVIPVSGTALWTDLWVEPASGNSIPLVQEWIDFCLKTSVAPQLSLLSQVSSPIIVGMKPEDLPANVRTNPVLLPDAKILERSEFLLPFGDAGIAQYRSHWQEMRKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYU0</accession>
    <name>A0A2G4EYU0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54656">
        <property type="protein sequence ID" value="PHX54656"/>
        <property type="gene ID" value="CP500_014960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="12963" checksum="41ACFEFA6DB9E7E2" modified="2018-01-31" version="1">MQVTVKGDRANCPVERTLEVIGGRWKVLILRELFPGVKRFNELQRAVNGITQKMLTQQLREMESDGIVHREVYLQVPPKVEYSLTALGESLKPIIDTMHEWGIQHLVITKSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ74</accession>
    <name>A0A2G4EZ74_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54823">
        <property type="protein sequence ID" value="PHX54823"/>
        <property type="gene ID" value="CP500_013925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="45"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="11941" checksum="0F01F3078DCF5BA0" modified="2018-01-31" version="1">MGWFKRLFGLEKPETQAEPMAQVVQQAAASQSIAPAKVGPDGNFDESGLAKRVALAFDEDSEVADIDTVWVAQLSGTVVLKGKVPSQEILNKLVAIASAEEGATGVQSDQVTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ91</accession>
    <name>A0A2G4EZ91_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribulose bisphosphate carboxylase small subunit</fullName>
            <shortName evidence="3">RuBisCO small subunit</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cbbS</name>
        <name evidence="3" type="synonym">rbcS</name>
        <name evidence="5" type="ORF">CP500_015690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterohexadecamer of 8 large and 8 small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Carboxysome</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RuBisCO small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54507">
        <property type="protein sequence ID" value="PHX54507"/>
        <property type="gene ID" value="CP500_015690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019253">
        <property type="term" value="P:reductive pentose-phosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03527">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00859">
        <property type="entry name" value="RuBisCO_S_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024681">
        <property type="entry name" value="RuBisCO_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000894">
        <property type="entry name" value="RuBisCO_ssu_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036385">
        <property type="entry name" value="RuBisCO_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31262">
        <property type="entry name" value="PTHR31262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00101">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00152">
        <property type="entry name" value="RUBISCOSMALL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00961">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55239">
        <property type="entry name" value="SSF55239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="1 3" id="KW-0113">Calvin cycle</keyword>
    <keyword evidence="2 3" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="3" id="KW-1282">Carboxysome</keyword>
    <keyword evidence="3" id="KW-0601">Photorespiration</keyword>
    <keyword evidence="3" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RuBisCO_small" evidence="4">
        <location>
            <begin position="9"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="13046" checksum="670AC40ED14EB2DB" modified="2018-01-31" version="1">MKTLPKERRYETLSYLPPLTDAQIAKQLQYILDQGYIPGVEFNETSAAEMRYWTLWKLPLFHARSVQEIMTEINACRQENPACYIRVMGFDNVKQCQVLSFIVHKPNTRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZD3</accession>
    <name>A0A2G4EZD3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GAF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54838">
        <property type="protein sequence ID" value="PHX54838"/>
        <property type="gene ID" value="CP500_014005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHYTOCHROME_2" evidence="1">
        <location>
            <begin position="18"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="164" mass="18663" checksum="3328558B0111F78F" modified="2018-01-31" version="1">MSDDRLQKIANGLTNRLKRDVLIEKSLSEIREVLQSDRAVLYHFYRKWQGQVTCEMLSAIELSILGSTGADECFNDEYAALYEGGRVRAIADIELEPLHQCHREFLRSIKIRANLVVPILTAKGLWGLLIAHQCSGPRTWLLSDIEFMQKQAQNMAMSPTIQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZD6</accession>
    <name>A0A2G4EZD6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54848">
        <property type="protein sequence ID" value="PHX54848"/>
        <property type="gene ID" value="CP500_013785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009306">
        <property type="entry name" value="DUF963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06131">
        <property type="entry name" value="DUF963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="11531" checksum="9FAAB8412BBA15C8" modified="2018-01-31" version="1">MLDWRRIGVYPLGRTLVYWQWWQIRHSYGSSCNWLGRARGCWTGIRSSTGIRSSTGIRSSTGIRSSTGIRSSTGIRSSTGIRSSTGIRIGSYCSRTAAQLRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZF4</accession>
    <name>A0A2G4EZF4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54896">
        <property type="protein sequence ID" value="PHX54896"/>
        <property type="gene ID" value="CP500_013755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013834787" evidence="2">
        <location>
            <begin position="35"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="208" mass="23150" checksum="6619028A077BEA68" modified="2018-01-31" version="1">MVHSRTVYWLRSTAQIALVAIATLTLWQAPQAQAQQPSGLDNRQQVEPADDPTDPNNLRPVSQSNSILSIPGGQRLMTEASSAISKQNYTVASQKLQESRQIFNQLSNFYQQLSSSFAGIDIRLADSNRTKAVETAQMRDEATYLLALVHRAQNKPELAVPLLIQIIRSQQPTRDLGKKAYQQLVELGFVDMPYPRPAANTQPTPPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZL7</accession>
    <name>A0A2G4EZL7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54637">
        <property type="protein sequence ID" value="PHX54637"/>
        <property type="gene ID" value="CP500_015050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7317" checksum="56AC0DFBB22E1094" modified="2018-01-31" version="1">MSVSQMTLEELFGQVMFSSVVTRHDRSCLRSALLERKLNEDEYAIINRLLYNVRRGWVKIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZL8</accession>
    <name>A0A2G4EZL8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54953">
        <property type="protein sequence ID" value="PHX54953"/>
        <property type="gene ID" value="CP500_013445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="211" mass="24194" checksum="DC33817CFDD7034F" modified="2018-01-31" version="1">MIQTISKTKTVMFDEFIAWYPENSIHRYELHNGVIVEMPLVQGDHSDVTGFISSEINFEIRRLQLPYSIPGDCLLKLSRNESGYQPDVIVLDRTALINEPRWKKESIITMGSSVRLAVEVVSTNWRDDYFFKASDYEEMGISEYWIVDYFGLGGRKFIGNPKQPTISVYQLVDGEYQVKQFRGSERVESLAFPELSLTAEQIFRAGLPACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZM0</accession>
    <name>A0A2G4EZM0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AbrB/MazE/SpoVT family DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54955">
        <property type="protein sequence ID" value="PHX54955"/>
        <property type="gene ID" value="CP500_013355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="7"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="12725" checksum="C60F47E16E88F282" modified="2018-01-31" version="1">MSKSIQTLIVKIDNSEGIRISRSLLEQIGISGAVEIEVHGDRIVIRAAQKQGADRFIISGTQKQDADWFVISGTLKPRTGWEEAFAKMAEQHDDVLLDDVTNTEWEELEWQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZV1</accession>
    <name>A0A2G4EZV1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55032">
        <property type="protein sequence ID" value="PHX55032"/>
        <property type="gene ID" value="CP500_012925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="502" mass="57026" checksum="28AE09B06244B2F2" modified="2018-01-31" version="1">MIEVEVHNSLLRFLRSHSEPHWPHHLTMARLVARALRLGRSALIQTGLPAGVYRQRYRVSYLMPILMWPEPVILVAPTRTIEHLKAVEIPRLQEWLQTDRPIATYDQNTDFRGLMLADPQSWLASRLATDSQPHSQIPTIIDGVDDLEVWTRQQLTLCLHPGDWNDLMLAVPQEADAILQGRVLLTRACFQHPAKPDECYLLETAEQNILVGLFERIASSALIPPAWSNFWHRWESNGKLRWAQINREAGSFSLYCAPVQVAEVLSKIWDNQPVVLIGGAVDLEPKAPIFREMLGLPELTTVKFSPDRQSELIQLYIPDGLPLPNTPEFQGVLIQEIRTLLCMSASVPGLTVLIVGDVPLKARIAARLASEFGSRVRVETTDVGENGILVTGWEFWREYQGELRAPHLLAIATLPLPSMENPLVTARVAYYKERRKDWFRLYLLPAALNELQRAIAPVRERQGVVAIFDNRVIYRSYGQQILAAMSPFARIDYLDTTWLTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZV9</accession>
    <name>A0A2G4EZV9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Type III pantothenate kinase</fullName>
            <ecNumber evidence="6">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">PanK-III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaX</name>
        <name evidence="7" type="ORF">CP500_014440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NH4(+)</name>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
        </cofactor>
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">A monovalent cation. Ammonium or potassium.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type III pantothenate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54737">
        <property type="protein sequence ID" value="PHX54737"/>
        <property type="gene ID" value="CP500_014440"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01274">
        <property type="entry name" value="Pantothen_kinase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004619">
        <property type="entry name" value="Type_III_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34265">
        <property type="entry name" value="PTHR34265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03309">
        <property type="entry name" value="Pan_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00671">
        <property type="entry name" value="baf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="150"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="33"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>a monovalent cation</name>
            <dbReference type="ChEBI" id="CHEBI:60242"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="306" mass="33498" checksum="5236256836C7C267" modified="2018-01-31" version="1">MENRSVENFTPETATTNFKSRLNSKTELKIALAIGNSRLHWGLFLGPTLQETWDTQHLSVDAVSQLSEDEKTEFLVQSAIAPIEQKYAQKLLSLCTNPELASRRAQQCVLPPLILASVVPEQTALWQSYPHVHTITLDQLPMEGLYPTLGIDRALTLLGVGIQLGWPTLVIDAGTALTFTGADVNRRLVGGAILPGLGLQLSSLGEKTAGLPLVTLPYNLPQRWVADTETAIKSGVVYGVVSAVNDFIQDWLRLFPNSKIAVTGGDRTLLLKYLASTFPDTVAAVIETPEAIFWGFRNVFQEGIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZX8</accession>
    <name>A0A2G4EZX8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isopentenyl-diphosphate delta-isomerase</fullName>
            <shortName evidence="6">IPP isomerase</shortName>
            <ecNumber evidence="6">5.3.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Isopentenyl diphosphate:dimethylallyl diphosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Isopentenyl pyrophosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Type 2 isopentenyl diphosphate isomerase</fullName>
            <shortName evidence="6">IDI-2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fni</name>
        <name evidence="8" type="ORF">CP500_012805</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>isopentenyl diphosphate = dimethylallyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23284"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="5.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5 6">Homooctamer. Dimer of tetramers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the IPP isomerase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55061">
        <property type="protein sequence ID" value="PHX55061"/>
        <property type="gene ID" value="CP500_012805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02811">
        <property type="entry name" value="IDI-2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00354">
        <property type="entry name" value="Idi_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011179">
        <property type="entry name" value="IPdP_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43665">
        <property type="entry name" value="PTHR43665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003314">
        <property type="entry name" value="IPP_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02151">
        <property type="entry name" value="IPP_isom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_dh" evidence="7">
        <location>
            <begin position="8"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_dh" evidence="7">
        <location>
            <begin position="176"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="9"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="68"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="294"/>
            <end position="295"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="344" mass="36880" checksum="BC59A3CE0D71727F" modified="2018-01-31" version="1">MPPSPIETRKADHLRLCIEEDVQFHETTSGLEHYRFDHCCLPELDRTEIDLTSTFLGKKLAAPLLISSMTGGTELAQTINYRLADVAQKYKIAMGVGSQRIAVENPQLADTFAVRRRAPDILLFANIGAVQLNYNYGLEQCQKIVDLLEADALILHLNPLQECVQTEGDTNFKGLLDKIAKLCEKLPVPVIAKEVGNGISGKMAKKLIAAGVSAIDIAGAGGTSWAKIEGERAKDGKQRRLGATFADWGIPTAECIVSTRAAAPDVPLIASGGLQHGLDAAKAIALGADMAGLARPFLQAAAESESALELLVEVLIAEIATVMFCTGCANLDELKHSGVLERLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F005</accession>
    <name>A0A2G4F005_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_012555</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55099">
        <property type="protein sequence ID" value="PHX55099"/>
        <property type="gene ID" value="CP500_012555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="8">
        <location>
            <begin position="40"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="273" mass="31529" checksum="79136AC10B40956F" modified="2018-01-31" version="1">MTIATSKKTSPDWPVIGFMAFLHIGALFALLPANFSWSAVELAVFLHWVTGGLGITLGFHRLVTHRSFQTPKWLEYFLVICGTLSCEGGPIDWVGMHRLHHVHSDTERDPHDSNQGFWWSHMGWMLSDLPIRVEIPRFTKDIGDDPVYKFLQAYFIPIQIVFGVLLYLLGGWSFVFWGVFMRIVVVFHCTWLVNSATHKFGYRTYESGDRSTNCWWVAVLTYGEGWHNNHHAFQYSARHGLQWWEIDLTWMTIQLLQTLGLATKVKLADIAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F012</accession>
    <name>A0A2G4F012_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55095">
        <property type="protein sequence ID" value="PHX55095"/>
        <property type="gene ID" value="CP500_012535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16377">
        <property type="entry name" value="23S_rRNA_IVP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="14177" checksum="0B1D2BA308631491" modified="2018-01-31" version="1">MENFQQLQVYQLAEKISNEIWFIVKKWDYFTKDTMGKQIVRSADSVGANIAEGHGRHSYQDNQRFVKIARGSLNETRHWLRLAYARNLLTQEQSDRLHPLLNELSPKLNAYLNSLKQKTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F030</accession>
    <name>A0A2G4F030_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000064">
        <property type="protein sequence ID" value="PHX55115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55115">
        <property type="protein sequence ID" value="PHX55115"/>
        <property type="gene ID" value="CP500_012440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8898" checksum="444FFEA5193F17FF" modified="2018-01-31" version="1">MEPADTYKGWIIQSQKVFYVEVWDSRGNRHVAVQNAKTEDEALELAKQWIDKYESKPGRMAMDEPYPFGDVIDMPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F048</accession>
    <name>A0A2G4F048_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-alanyl-D-alanine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55126">
        <property type="protein sequence ID" value="PHX55126"/>
        <property type="gene ID" value="CP500_012125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000667">
        <property type="entry name" value="Peptidase_S13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30023">
        <property type="entry name" value="PTHR30023"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02113">
        <property type="entry name" value="Peptidase_S13"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00922">
        <property type="entry name" value="DADACBPTASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="444" mass="47019" checksum="618286368A983224" modified="2018-01-31" version="1">MLDLFSSGIMSLWLDMAGVRSVGANTVSVLAWEGGVPGLVMAVDLANGGVSVANPDLPTAVAVQEFLKDLRVKGLTEGSQGVWVQAGMLPLVSQQGTTLMPGASLTKIATSLASLETWGANYQFETRFRGTGQIKNGVLQGDLVVSGGGDPLFVWEEAIAVGNALNDMGIRRVAGNLVVTGNFRMNNQSDPVTAGELLRQALDGRSWASEVQSIYSKMPPGTKRPQVSVVGGTVAEKFVGSGRLLMVRRSLPLVEILKQMNVHSDNDIAQMLADNLGGAKIVQQQATWAAGVPAAELQLVNGSGLGVENQMSPRAACAMMQAIGRFLQTTPLTIADLFPVSGRDRGTLEHRHIPPYAVVKTGTLDSVIALAGAIPTRDRGLVWFAIINRGTDWDSLRAQQDLFLQKLVQRWGTASTLPLAITPHIDGTRPALGAANRSDILLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F055</accession>
    <name>A0A2G4F055_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Urease subunit gamma</fullName>
            <ecNumber evidence="4 5">3.5.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Urea amidohydrolase subunit gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">ureA</name>
        <name evidence="6" type="ORF">CP500_012210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4 5">
            <text>2 H(+) + H2O + urea = CO2 + 2 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20557"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the urease gamma subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.5" evidence="4 5"/>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015179363.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000063.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55141">
        <property type="protein sequence ID" value="PHX55141"/>
        <property type="gene ID" value="CP500_012210"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00258">
        <property type="reaction ID" value="UER00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00390">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00739">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012010">
        <property type="entry name" value="Urease_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002026">
        <property type="entry name" value="Urease_gamma/gamma-beta_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036463">
        <property type="entry name" value="Urease_gamma_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00547">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001223">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54111">
        <property type="entry name" value="SSF54111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00193">
        <property type="entry name" value="urease_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="100" mass="11111" checksum="5AC11D4B4F64AB78" modified="2018-01-31" version="1">MQLTPQEKDKLLIFTAALVAERRKQRGLKLNYPEALAYISAAILEGARDGLTVADLMSYGTTLLTREDVMEGIPEMVHEVQVEATFPDGTKLVTVHDPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0F9</accession>
    <name>A0A2G4F0F9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55249">
        <property type="protein sequence ID" value="PHX55249"/>
        <property type="gene ID" value="CP500_011755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="30856" checksum="F0391593FE13EE41" modified="2018-01-31" version="1">MTQVIGIDLGGTAIKLGRFSADGICHQSLTVPTPQPATPEAVLAAMVDAISELNPVENAVKAIGLGTPGPADATGRIARVAINLKNWQNVPLADWLEAKTGLPTILANDANCAGLGEAWLGAGRHFNNLILLTLGTGVGGAVILDGKLFSGHQGAAGELGLITINPDGPECNSGNRGSLEQYVSVQAIRRETGLEPLELANLAKSGDAKAIEYWQNYGRYLGIGLASLIYVLTPEAIIIGGGISAGAEFFLPAVIAEIERRVLPSSREDLQLLVAELGNQAGIVGAAKLAWIKCNWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0H2</accession>
    <name>A0A2G4F0H2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55262">
        <property type="protein sequence ID" value="PHX55262"/>
        <property type="gene ID" value="CP500_011820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="55"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="30613" checksum="47A8503899067E5A" modified="2018-01-31" version="1">MQDETLKKERQFHDAWASTIDVDGIRVNDYFEACTAPENRFIVQQMGDITGKRLLDLGCGAGENSVYFAKKGAHCVAADYSQGMVEVALKLAETNGVKIEGCTVNAMALDFPDNSFDIVYASNLLHHLPEPEKAIREMHRVLKPGGKACFWDPMKHNPVINVYRRMATEVRTEDETPLDINIVKLVKSLFSETAYDTFWLTSLWIFLRFYLIEKVHPNEERYWKKIIIEQERLKPEYSRLEGLDGWLKKLPLMKRLAWNLAVVATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0J6</accession>
    <name>A0A2G4F0J6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Adenosine 5'-phosphosulfate reductase</fullName>
            <shortName evidence="10">APS reductase</shortName>
            <ecNumber evidence="6 10">1.8.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">5'-adenylylsulfate reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8 10">Thioredoxin-dependent 5'-adenylylsulfate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cysH</name>
        <name evidence="12" type="ORF">CP500_013220</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10">Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 10">
            <text>[thioredoxin]-disulfide + AMP + 2 H(+) + sulfite = [thioredoxin]-dithiol + adenosine 5'-phosphosulfate</text>
            <dbReference type="Rhea" id="RHEA:21976"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="1.8.4.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 10">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.10" evidence="6 10"/>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54977">
        <property type="protein sequence ID" value="PHX54977"/>
        <property type="gene ID" value="CP500_013220"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00402"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011798">
        <property type="entry name" value="APS_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000857">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02055">
        <property type="entry name" value="APS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00434">
        <property type="entry name" value="cysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="11">
        <location>
            <begin position="36"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; cysteine thiosulfonate intermediate" evidence="10">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX54977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="244" mass="27906" checksum="D0BD9735D6448A20" modified="2018-01-31" version="1">MVAIQTNLNIAALEAEYSEKTPRDILKFALETFDNISISFSGAEDVVLIDLASKITKNIRVFTLDTGRLHSETYQFLEQVRKHYGIKIEVMFPDAAEVQALVDEKGLFSFYQDGHKECCGVRKVKPLRRKLKTLDAWITGQRKDQSPSTRNHIPVIEVDSAFSTPDHELIKFNPLANWSSAEVWDYIRALDVPYNKLHERGFVSIGCEPCTKAILPNQHEREGRWWWEESTLKECGLHAGNAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0M9</accession>
    <name>A0A2G4F0M9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55324">
        <property type="protein sequence ID" value="PHX55324"/>
        <property type="gene ID" value="CP500_011295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="8918" checksum="45F03FDBFCE346FC" modified="2018-01-31" version="1">MGHWSWGIGHGASGIGHRALGIGHWASGIGYRELGIGNPLNLLNPLQNPLPNFLLSATSVTSVTKSVAELQLSNNSVALTQGSEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0N6</accession>
    <name>A0A2G4F0N6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system YafQ family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55329">
        <property type="protein sequence ID" value="PHX55329"/>
        <property type="gene ID" value="CP500_011330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004386">
        <property type="entry name" value="Toxin_YafQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15738">
        <property type="entry name" value="YafQ_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="93" mass="10635" checksum="42E40E8803E29E24" modified="2018-01-31" version="1">MEVVWSSGFNRSFRKITKKNPQLKDQIANVLRLLGDDPFTPSLKSHKLGGDLEGLWSCSVTYDCRIIFNFSEDEELLEMVILLVDIGSHDDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F117</accession>
    <name>A0A2G4F117_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">valS</name>
        <name evidence="14" type="ORF">CP500_010755</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55451">
        <property type="protein sequence ID" value="PHX55451"/>
        <property type="gene ID" value="CP500_010755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="17"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="12">
        <location>
            <begin position="667"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="13">
        <location>
            <begin position="901"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="616"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="851"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="906"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="637"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX55451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="965" mass="108499" checksum="6B3BAA6A99F9A640" modified="2018-01-31" version="1">MTANLPPQYDPFATEAKWQKYWEDNQTFKADPEKSGEPYCVVIPPPNVTGRLHMGHAFNNSLVDALIRYHRMIGDNTLCLPGTDHASIAVQTILEKQLKAEGKTRDDLGREKFLERAWNWKAESGGAIVNQLQRLGLSADWSRERFTMDEGLSKSVLAAFVRLYEEGMIYRGNYLVNWCPASQSAVSDLEVESKEVDGNLWHFRYPLSDGSGFVEVATTRPETMLGDTGVAVNPNDDRYKHLIGKTLTLPILNREIPIFADELVDPTFGTGCVKVTPAHDPNDFEMGKRHNLPFINIMNKDGTLNENAGEFQGQDRFVARKNVIKRLETDGFLVKIEDYKHTVPFSDRGKVPVEPLLSTQWFVKTRPMADKALEFLDQHNQPQFVPSRWTKVYRDWLVKIKDWCISRQLWWGHQIPAWYAISETGGEILDNTPFVVAANEAEAREKAVAKFGANVKLEQDPDVLDTWFSSGLWPFSTMGWPEETADLARYYPNTTLSTGFDIIFFWVARMTMMAGYFTDKMPFETVYIHGLMLDENGKKQSKSAGNGIDPLVLMDKYGTDALRYSLMRETAGAGQDVRMDYNRQSHESATVEASRNFTNKLWNAARFVMMNLEGQTPQQLGNPYPPQPPLAKGGSEEEEVSLAKGGSEEEEVSLVEGGSEEGLELCDRWILSRYYQVVQQSRNDFESYALGEAAKGLYEFIWGDFCDWYIELVKSRLQQDAEPNSKKAAQQTFAFVLEGILKLLHPFMPHITEEIWHTLTQKGEEECLALQAYPEVQASLINPDLEQQFELLFGTIRTIRNLRADTDIKPGVKVTAILQSESEKERQILSDGAIYIKDLARVENLTITASLEEEPPLNPPLGKGGQGGSLNPPLGKGGQGGSIAGVVGTVQVLIPLAGVVDLVALRVKLEKKLAKIEGEIKHTSARLTNQKFVEKADPQVVQVARDGLAEAEKQAEILRDRLKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1A7</accession>
    <name>A0A2G4F1A7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55247">
        <property type="protein sequence ID" value="PHX55247"/>
        <property type="gene ID" value="CP500_011740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="257"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="322" mass="36590" checksum="4BF8647555098461" modified="2018-01-31" version="1">MNFINPKTDFAFKKIFGSAESKDILISFLNALLYEARPVIEDLEIIDPYLAPNIKGIKDTYLDVKAKISGDKTVIIEMQVLNVEYFQQRVLYNATKTYSMQLSTGTGYSKLNPVIALTITDFKMFENMDTVISHFIFKEKTFLVDYLADQFELVFVELPKFNKGLDELETLTDKWIYFMKTAQALHSVPEELGNVQELKQAFTIASTANLNAQELDDLDKREMWIQDQRGSISLATKIALAEGIEQGIELGIEQGIEQGIKQGNLRLITRQLERSVGELSPDIITWISQLSVEQLESLGEAVLDFTKLSDLTTWLQVHNNPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1H4</accession>
    <name>A0A2G4F1H4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein-arginine deiminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_009830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55621">
        <property type="protein sequence ID" value="PHX55621"/>
        <property type="gene ID" value="CP500_009830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004668">
        <property type="term" value="F:protein-arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018101">
        <property type="term" value="P:protein citrullination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004303">
        <property type="entry name" value="PAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013530">
        <property type="entry name" value="PAD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036556">
        <property type="entry name" value="PAD_central_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10837">
        <property type="entry name" value="PTHR10837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03068">
        <property type="entry name" value="PAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110083">
        <property type="entry name" value="SSF110083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="PAD" evidence="3">
        <location>
            <begin position="449"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="189"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="819" mass="92565" checksum="E9F7FB6E8E91C15A" modified="2018-01-31" version="1">MRLVKYIAIAIVNTFGVIIGIIWVAVPQTLAQPSLNYQLAISQRQPEGESPRSLPELYKLRDRLKLELDQIAKNPDRTSFFSEPWKPQTQRQKSENLTQQLENLKSRIQIEETAKNTWNYSAKIAREAVVIGRTAKSSPASWEQSQRLWQSAINTLRQIPHGSFLADGAIDKTIEYQGNLTVATYELQVARNVQKALAEEQQKKELERQAFEKKEQARKELERQEFEKKELVRKELEKKEFEKNEIVRKEREKQELVRQEIARKEREKQELARQELERQALELNQPTIKPNPIPFLPATPSSNFFFAGDTNRDGEINQQDEVGKEKWSLSSGALVLFNDKSSAPKIPVWQETKVSAPRRPAMLSQVHLKLSDNFKNSQIFITADSLASPHISVFQKTADGWQAVDISGTKQLVFSTDIVLGIEAKQFADRNWNGLINLKATAINNGIEIASNTIQLGVTPWIMPSNSAPVTEVQVSDRGSANSEFISQLKQAVEPTGALVKVIQGDRAWMQDTQKNGYVQFTEKLKLRNLNVAVKSNSNSTENNQAKSNSDRDLSVFKIGKPRNEESVNQWADGYGNLQVTPPIPAYPMGRVYYGNPGNASFNPEVLDFVKAQRIQGQPVDIDTSWLLTRQVDEIINFIPSTTPGKYIMAIASPEAGVKLLEELAEKGYGDVTINRGLSNEITVSAALNNQALIQHNLNLQKQKLNPIIEKLKREFSLTDDQIIQVPAMFGYSGYAWWPNMVNSVPVNGSLLVSNPRGALIDGKDYTQKKLRQLLLPFGVNISFLDDRYYQELRGNVQSATNTVRKGEERPFWQSLPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1N0</accession>
    <name>A0A2G4F1N0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55656">
        <property type="protein sequence ID" value="PHX55656"/>
        <property type="gene ID" value="CP500_009605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="18605" checksum="458EA37CB867CCB6" modified="2018-01-31" version="1">MSNKYQPHIHVLAEDDANRQIANGFLLESNLDNRAVKVLPLRGGWKKTLEEFNKKYASEMRQLPERMMVLLIDFDNDENRLSYVESHIPDDLKARVFVLGVLSEPENLKRESNKTFEEIGEALAKDCSNNKNELWGHNLLKHNKPELDRMATLVKPFLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1P2</accession>
    <name>A0A2G4F1P2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55659">
        <property type="protein sequence ID" value="PHX55659"/>
        <property type="gene ID" value="CP500_009625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="12150" checksum="D1B20B3FEF90D7AB" modified="2018-01-31" version="1">MSDIFVMVRNQNNIAMTSVDGIAFITLLNRDGRVLAEETVALMEADAGFDDLAAGQYTVIVRHELVEPRSATWDVTIGNQDQVIILTFIYLEPERVLLRILATIEERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1R1</accession>
    <name>A0A2G4F1R1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DegT/DnrJ/EryC1/StrS family aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_011135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55417">
        <property type="protein sequence ID" value="PHX55417"/>
        <property type="gene ID" value="CP500_011135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="42915" checksum="02CC2309094C3380" modified="2018-01-31" version="1">MVSRVNNVPPLDLSRQYAQIGDEIATAVQKVLASGAYIGGPAVKNFEQEFANYIGVSDCVGCNSGTDALILALRALKIGPGDEVITTPFTFFASAETISAVGATPVFVDIDAATFNMDLDRLEAAITQKTKAIMPVHIFGQPMDMTRLMDIANRHNLAVIEDCAQSVGAEWRSQKVGSIGHIGCFSFYPTKNLGACGDGGAVTTNDRALAATMRMLKEHGQSSRYFYEEIGYNSRLDALQAVILTIKLRYLDTWNDQRGDRAKLYSEFLDRVPGVAVPTELPGAKGVWNQYTIRLKSPEDEPNPSGNFRDSVRTKLQECGIGSMVYYPLPLHLQPVYKSLDYQLGQLPIAEQVCHEVLSLPMFPELSRDQQERTIYALKDSLAQSGRLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1R6</accession>
    <name>A0A2G4F1R6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PucC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55704">
        <property type="protein sequence ID" value="PHX55704"/>
        <property type="gene ID" value="CP500_009415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06176">
        <property type="entry name" value="MFS_BCD_PucC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026036">
        <property type="entry name" value="PucC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004896">
        <property type="entry name" value="PucC-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23538">
        <property type="entry name" value="PTHR23538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03209">
        <property type="entry name" value="PUCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016565">
        <property type="entry name" value="PucC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="477" mass="50794" checksum="04CE06FCEB95C812" modified="2018-01-31" version="1">MSIDDLSDSRLTDSATPAIKRVNLLTMFRLGLFQMGLGMMSILTLGVLNRVMIKELAIPATVVAGTLAMHQFVAPARVWFGQMSDAKPLFGHHRTGYVWLGGVLFVISAFLAVQVMWRLGDSLEAVGWTTPTYGWVGLLGLIFALYGIAICSSSTPFAALLVDVSDEEDRSKLIGVVWSMLMVGIIIGAIVSSGLLKQIDGDVPLEVLQVSINGLFVKVPAVVLLLVGVSTFGVEKKYSRYGVRSTAVNREDKITLGSALRILTASRQTGLFFTFLLIMTICLFMQDAVLEPYGGEIFKMPISETTRLNAIYGTGVLVGLSATGFLIVPRIGKQNTIRLGCLSVAVCFGLIIASGFTGNPILFKSALFLFGLASGITTTGALSLMLDLTAAETAGTFIGAWGLSQAMARGIATVSGGAILDLGRSLFGVPMLAYGLVFAVPAVGMVVAVWLLGRVDVREFQDNAKSAIATILENELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1R7</accession>
    <name>A0A2G4F1R7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF952 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55689">
        <property type="protein sequence ID" value="PHX55689"/>
        <property type="gene ID" value="CP500_009325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009297">
        <property type="entry name" value="DUF952"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129">
        <property type="entry name" value="PTHR34129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06108">
        <property type="entry name" value="DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="12950" checksum="5212B37DC32E7E7C" modified="2018-01-31" version="1">MSVIFHISKSQEWEAAKQLQSYRGDTLDSEGFIHCSTIPQITRSANKFFVGQTGLLLLWIESEKVQAEVKYEPAAGDYYPHIYGPLNVDAVLKVIEFEAGADGKFELPEELRDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1X6</accession>
    <name>A0A2G4F1X6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55749">
        <property type="protein sequence ID" value="PHX55749"/>
        <property type="gene ID" value="CP500_009080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="59" mass="7201" checksum="AFCF94B6557E80A5" modified="2018-01-31" version="1">MAETYYFIKDLINDLERGRIRIMSFQRGFVWEPNRVSYFIDSIYRLSQKTGDRLYQSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F242</accession>
    <name>A0A2G4F242_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55843">
        <property type="protein sequence ID" value="PHX55843"/>
        <property type="gene ID" value="CP500_008815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="14"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="284" mass="29675" checksum="AE8520E10F214386" modified="2018-01-31" version="1">MSYTQSLSGENPGYILILIDQSGSMSSKFGGTTGGSKAEECAKAVNRVLRELGLTCTVGSVIKNRCDISLLSYGASGNQAKNALSGQLASKPVVTMQELVNCCLKVDTVKMKISDGAGGLVEVDEQFPIWIEPIASGGTPMAAAFEVACNLVDSWTKSHQASFPPIVINITDGAPDSQSDAQVAASRLSQLGTSDGTTLILNAHISEGKAAKVQLPSSPTELPPGDGNAKFLFDISSELPPVMFERAGAVGYNNLAPGARGFVYNADAETMIRLLDVGTRSNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F299</accession>
    <name>A0A2G4F299_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Photosystem I reaction center subunit XII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_008530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cellular thylakoid membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the phycobilisome linker protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55868">
        <property type="protein sequence ID" value="PHX55868"/>
        <property type="gene ID" value="CP500_008530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008213">
        <property type="entry name" value="CpcD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001297">
        <property type="entry name" value="PBS_linker_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038255">
        <property type="entry name" value="PBS_linker_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016470">
        <property type="entry name" value="Phycobilisome"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01383">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00427">
        <property type="entry name" value="PBS_linker_poly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005898">
        <property type="entry name" value="Phycobilisome_CpeC/CpcI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01094">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51441">
        <property type="entry name" value="CPCD_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51445">
        <property type="entry name" value="PBS_LINKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <feature type="domain" description="PBS-linker" evidence="8">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="CpcD-like" evidence="7">
        <location>
            <begin position="204"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="255" mass="28492" checksum="5D97C435E29025E5" modified="2018-01-31" version="1">MSVVLDAPVELWPTSSSDDQQAVIRAVYKQVLGNPHVMESERLTVPESQLCDRGMTVREFVRAVAKSDFYRSRYFESCAPYRFVELNFKHLLGRAPLDQAELSEHIRTCIEKGYDAEIDSYLDSQEYQDKFGENTVPYYVGAKSQVGQKQVGYNRTLSLYQGYAGVDSAFTASRLVDFVAGNSGNKITLPTTGGRISAYKDATEKMFKILVKGAKFDSPRRLSNTEYLVSGGKMTPQIQRIHRAGGKIVSITEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2A7</accession>
    <name>A0A2G4F2A7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="9">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 15" type="primary">leuS</name>
        <name evidence="15" type="ORF">CP500_008255</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55878">
        <property type="protein sequence ID" value="PHX55878"/>
        <property type="gene ID" value="CP500_008255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="13">
        <location>
            <begin position="40"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="14">
        <location>
            <begin position="223"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="417"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="610"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="12">
        <location>
            <begin position="695"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="610"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="613"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX55878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="851" mass="96542" checksum="025E41A90E0F52D8" modified="2018-01-31" version="1">MESKYNPQSIEEKWQQTWAEQNLDQMPENSEKPKFYALSMFPYPSGNLHMGHVRNYTIIDVIARLKRMQGYRVLNPMGWDAFGLPAENAAIERGIPPAQWTYQNIAQMKGLFQRLGISFDWTKEVTTCSPDYYRWTQWIFLQFLDAGLAYQKEAAVNWDPIDQTVLANEQVDNEGRSWRSGAQVERKLLRQWFLKITDYAEQLLNDLDKLPNWPERVKLMQANWIGKSVGAYLEFPIVGIDENIAVFTTRPDTVYGVSYVVLSPEHPLTNRVTTPDRKAAVETFVKEVALQSEMDRTAEDKPKRGVPTGGKVINPFNGEEIPIWIADYVLYEYGTGAVMGVPAHDKRDFQFATEYELPIKIVIVDDDEWPLTEAYTEPGIMINSESFNGMDSIKGKAAIIHYAENSGYGKARVQYRLRDWLISRQRYWGAPIPVIHCPNCGTVPVPQSDLPVLLPENVEFTGKGSPLAKMEDWVNVPCPSCGTPAKRETDTMDTFMDSSWYFLRYPDASNQDQVFDSAKTNDWMPVDQYVGGIEHAILHLLYSRFFTKVLRDRGLIDCDEPFKRLLTQGMVQGLTYKNAVTGKYIPSAEVDATNPKDPETGEALEVFYEKMSKSKYNGVDPLQVMEKYGVDTARMFILFKAPPEKDLEWDDADVEGQFRFLNRVWRLVTEFASPPPTPPCQGGEKEVLSKPEQDLRRAIHVAIKEVSEDLEGDYQFNTAVSEMMKLNNALTDAKCKDSPIYAEGISTLILLLAPFSPHIADELWHLIGNSESVHTQTWPSVDVSALVTDEITLVIQVMGKTRGTIQVPSGADKAALENYARESELAKRHLEGKEIKKVIVVPGKLVNFVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2E9</accession>
    <name>A0A2G4F2E9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_008250</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OprB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55953">
        <property type="protein sequence ID" value="PHX55953"/>
        <property type="gene ID" value="CP500_008250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038673">
        <property type="entry name" value="OprB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013431598" evidence="2">
        <location>
            <begin position="19"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="4">
        <location>
            <begin position="147"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="281"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="673" mass="72926" checksum="2579F7AC66EC53A2" modified="2018-01-31" version="1">MSKSLFFQILLTATPAFFCINLLHCPAISAAENSVLETEEATAEIAESPIAELAASPIDTQTNPAVTNEKPAAIASENQLETNPKEVAAVSESSEVKSTETAAEASNESSVLAESIQTPENPVNIADIQQVDTLETNDASKIEQVTSVSQLSDVKPTDWAFQALQSLVERYGCIAGYPDGTYRGNRAMTRYEFAAGLNACLDKVAELIKAGGSNFVKKEDLEKVQKLQEQFAAELATLRGRVDVLEARTAELESNQFSTTTKLNGTVWFNLTSAFPTGDITAERSRTTPNSAFAPPTRDANNRPTRVERGTPETTFSYYSFLTLNTSFTGKDSLVTQLVFGNGNSPANELVSAGFYNSWGTPFLDQTGVPTANTVGIREMSYTFPVGDKVQVAIGPRLNYYRYFDGNRFTFFMKGATSFNSNGSTLLNAVDRGSGAAVTWQVAKPLRFTAAYMAENTEFLNPAVYNTASNPSDGLFNSSNTITAQLEYAPSNSFNLRLIYARSSLKPYNGFIGGAVGEPLPYGYADDGFGGKVRDSGADTFVVNFDWLLGRNFGLFGRYSYGQLEVNPVNRDRSGGDIKVQSLQVGMGFPDIGKKGALGVLSFVIPQDYISGRRFLLSGGGNGGTQYEIEGSYYYPITNNIAIVPAFYAIFNANNFDGNPTVFVGNLRTQFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2G1</accession>
    <name>A0A2G4F2G1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55932">
        <property type="protein sequence ID" value="PHX55932"/>
        <property type="gene ID" value="CP500_008135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="295" mass="33792" checksum="5E482FF909AF3695" modified="2018-01-31" version="1">MIFINPKTDYAFKKIFGSSESKDILISFLNALIYDGNPTIEDLEIINPNLPPKIEGLKDSYLDVKAKLQDGTLVIIEMQVLNVESFGKRVFYNAAKTYAFQLQAAQAYRLLKPVIALTITDFEMFPNSEDFISRFVLKEVDKNFTYPENELDLVFVELPKFMKGEEQLETLADKWIYFMKNARSLTSVPEIMDSVPEIHQAFDIANQVKLSREEVEEFDRREQFIYDQQGAIIKASREAREEGREEGREEGREEGMHSKAIAIAQKLLPQLDNATISQVTGLSIEDVQNLREANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2H4</accession>
    <name>A0A2G4F2H4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_007900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55961">
        <property type="protein sequence ID" value="PHX55961"/>
        <property type="gene ID" value="CP500_007900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="8">
        <location>
            <begin position="33"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="276" mass="32732" checksum="A72027ED2E6D5A24" modified="2018-01-31" version="1">MQTTLTRSPLDWTAVFFFTTIHALALLAPWCFSWSAVGITLFLHWLFGSIGICLGYHRLLSHRSFQVPKWVEYAIALIGAFALQGGPIFWVAGHRLHHAYTEDVDKDPYSARRGFWWSHMLWIFYPDSEFFDYERYQRFAPDLVRDRFYCWLNRNFLLLQIPLGLLLYALGGWSFVIWGMFVRAVLLWHSTWFINSVTHLWGYRTFDTKDNSRNLWWAAILTYGEGWHNNHHAHPNVAKAGWRWWEYDPTWWAIWLLKKLGVARKVVMPPTQNATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2I9</accession>
    <name>A0A2G4F2I9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="7">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ddl</name>
        <name evidence="11" type="ORF">CP500_007925</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55966">
        <property type="protein sequence ID" value="PHX55966"/>
        <property type="gene ID" value="CP500_007925"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 7 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="137"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="356" mass="38763" checksum="F7A97A330CB4E2E2" modified="2018-01-31" version="1">MTKMRIGLLFGGRSGEHEVSISSARAIARALASDENATKYEVQPFYIQKDGRWLSGNIPQQVLESGKPLEIEQKAENESPLSREFPSFNAVDVWFPVLHGPNGEDGTVQGLLKLMQIPFVGSGVLGSAMGMDKIAMKMAFAHAGLPQVKYIAVNRSQIWSNPCVFPKLCDQIEETLGYPCFVKPANLGSSVGISKVRSRTELEAALDSAASYDRRIIVEAGVIARELECAVLGNDNPQASTVGEISFNSDFYDYETKYTQGQADLSIPAKASSAIISKIQDMAVQAFLAIDGAGLGRVDFFYVESTGEVLINEINTFPGFTATSMYPQLWEASGISFSELVDRLIQLALERHGDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2K8</accession>
    <name>A0A2G4F2K8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4435 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55986">
        <property type="protein sequence ID" value="PHX55986"/>
        <property type="gene ID" value="CP500_007805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029492">
        <property type="entry name" value="DUF4435"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14491">
        <property type="entry name" value="DUF4435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4435" evidence="1">
        <location>
            <begin position="30"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="349" mass="41182" checksum="F07BF8167A6D1978" modified="2018-01-31" version="1">MIDDKTYKEISERIVADAFHKGCNLSVLCEDIYDNDFWRCIIEDAKPSLKDKLDFPNPNPKGTRGKDILKKLKNYVNKKMIICVDSDCEYLYDNNVWYIDTYIYHTIVHSRENFQCNHLSLNEICKQIADKSYNFRTLFEHISEIISILFYIWIHLKETGDYSRFDGIINNEQFRKILNFQDIQYNSLEDEINLYQTIKDRVDCVLKNLEASMSEGWYKSVIEYEVPQLRTKLIEQYEIHPEETLSFFYGHGVLENLVEPLTIKITDLLKKSRIEEVRQELSQASENDIRNTISRIENASRQDVKTKIGDSFKYIIYAIKNKYIKEIQQKLVSELSCDGETEIISGKCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Z8</accession>
    <name>A0A2G4F2Z8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">rsfS</name>
        <name evidence="3" type="ORF">CP500_007120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with ribosomal protein L14 (rplN).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56143">
        <property type="protein sequence ID" value="PHX56143"/>
        <property type="gene ID" value="CP500_007120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="143" mass="16219" checksum="EBB6A0CE9AF8F883" modified="2018-01-31" version="1">MSDRTQLEYTLAQSTATLGEYPDPTRPLALTIAHAAEDRKGHEIVLLCVSEVCYLADYFVIVTGFSNVQVRSISQAIADQVEEEWQRLPLRIEGQSDASWIVMDYGDAIVHILKPQEREFYNLEAFWGHAERIDFSVAEVDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F307</accession>
    <name>A0A2G4F307_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56142">
        <property type="protein sequence ID" value="PHX56142"/>
        <property type="gene ID" value="CP500_007105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="98"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="27526" checksum="4CD5DDE7D9165E38" modified="2018-01-31" version="1">MTKIIKNPGYCYTCDQEVEFSSQQKWLRDHYKCNNCGSIPRERALMYCIEKFYPQWKQLSIHETSPANRGASLKLKNNCLKYQTSQYFPEFPLGETHSSGWRNEDLEHQTFADETFDLVISQDVMEHIFNPEKAFSEIARTLKPGGAHIFTVPIVNKERPSSIRATLEVNGEINYLEEAQYHGNPVNPKGSLVTRDWGYDICDFILKHSGLYTTIVYIDDISLGIRAEYIEVLISRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F333</accession>
    <name>A0A2G4F333_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="7">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraY</name>
        <name evidence="8" type="ORF">CP500_007015</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56145">
        <property type="protein sequence ID" value="PHX56145"/>
        <property type="gene ID" value="CP500_007015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="367" mass="38893" checksum="107820B5389DD722" modified="2018-01-31" version="1">MDKKVSLSMRLKPTGKNLFLLLGLGISIAAIGLDLAAGRFLNSPASLFNPLVVCALVASGLGYVVIPVLQRMKAGQVIREDGPQAHLKKAGTPTMGGIFFVPAGVVVAILWSRFNSDVVAVSALTLAYGFIGWLDDWQILRRKSNKGISPRMKLALQVGFAALFCLWLMFHNPAISTNISLPFGWVLPLGFLFWPLAGFVLVAESNATNLTDGVDGLMGGLGAIALLGLGASVASTSPELMIFCACMSGSCLGFLAHNRNPAKVFMGDTGALALGGALAAVALLTNSLWVLLIISGIFLVETLSVIAQVSYYKATKGPDGIGKRLLKMAPLHHHLELSGWLETQVVGIFYLTNIVLVLMILIFTGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F356</accession>
    <name>A0A2G4F356_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56191">
        <property type="protein sequence ID" value="PHX56191"/>
        <property type="gene ID" value="CP500_006695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="2">
        <location>
            <begin position="252"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="370" mass="43154" checksum="08E12B0EF6AF0FEB" modified="2018-01-31" version="1">MLKRIYIDNFRCLVNFELDFDAINLFLGANGSGKSTVFEVLQKIQALVSGDSKVEGIFKPADFTRWQTLQIQRFELEILGNDGCYKYQLQIDEYADKCRVRYESLLFDNQPLLQFEFGEVQLYRDDYSPGPKYQFDWSQSILPSLMPRKDNTKLTWFRERMARFIIVQVVPSLMVDESSQAQRRLTPKMENFVSWYRYLSEDQGKVAEIGNILRDVLDGFTNFKFERVSEDNLVLKLRFSGETDNIKPIEYRLRELSDGQKTLVALYALIHGTKSEDYTVWIDEPENFLALPEIQPWLIKIYDLCNEGKLQSLLISHHPELINYLLASPIGYWFERQSNAAVRVKKISNEVADNSGLQVSELIARGWLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3F9</accession>
    <name>A0A2G4F3F9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56313">
        <property type="protein sequence ID" value="PHX56313"/>
        <property type="gene ID" value="CP500_006175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="88"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="344" mass="37774" checksum="EECCE6A7C209D6BC" modified="2018-01-31" version="1">MFDVAVIGAGMAGLICANQLRLAGYSVVVVEKSRGVGGRVATRRVNGTRADHGARYLERQGDAVQGLIDVLLDRNILKLWTDTVCEFRQGELFSSPNSCYVAPAGMNAVGKYLAEGLEIWSGRRVQAISATDSQLWRLSLEVTDDNFERPQELIAKSIVVAIPAPQALMFLTSEIGLSPDFLDKLRSVEYDPCITVMAGYSAEHEQDLSILNSQWKTVSFTDNSELAWIGLDSSKRLESPQPVFVVHSSASFAECYFEATDLSSVGQHLLDRTSENLMPWLKQPEWFQVHRWRYAFCRNPLPVSCLPAAGTLPLVCAGDLCGEGQIEAALRSGLAASVWVNSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3K1</accession>
    <name>A0A2G4F3K1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Metal-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56057">
        <property type="protein sequence ID" value="PHX56057"/>
        <property type="gene ID" value="CP500_007440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018664">
        <property type="entry name" value="DUF2103_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09876">
        <property type="entry name" value="DUF2103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="10724" checksum="FB62A9D1F8C8E8F1" modified="2018-01-31" version="1">MNPQSKGRLVWNHSTHLDGLIPILERLTQKIGIHTVTPGVINKVKGHIPHMTLRVSVPIRGGFKIIARQGKTVQEVFILTTLGQGDLEEMIAKTLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Y5</accession>
    <name>A0A2G4F3Y5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56431">
        <property type="protein sequence ID" value="PHX56431"/>
        <property type="gene ID" value="CP500_005345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="15064" checksum="AEEEC5315F0FECB1" modified="2018-01-31" version="1">MFDSDKYSSLLSQYQPRIIKNADENEIFLEIVESLLSRKNLTLEKDTLLELLVKLIDDFEENHYQLNASTPHSRLLHLMDARSLEPADLVEIVGTIEMATAIVNSKLEITKKQAEALEEFFHVNPGLFLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F408</accession>
    <name>A0A2G4F408_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homogentisate phytyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_006530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56217">
        <property type="protein sequence ID" value="PHX56217"/>
        <property type="gene ID" value="CP500_006530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13960">
        <property type="entry name" value="PT_UbiA_HPT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044502">
        <property type="entry name" value="AtHST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="331" mass="36612" checksum="D55DB8BFA6F3A4C8" modified="2018-01-31" version="1">MSNNSIGKSGIDNNGLVPQGWLRAFWEFSRPHTIVGTSLSVLALYAIAQSNFILANSVLLPISFAWLACICGNIYIVGLNQLEDVEIDKINKPYLPIASGEFSRKTGELIVTATGIVAVLTAVLQGPFLLATVGISLAIGTAYSLPPIRLKRFPFWAALCIFTVRGAIVNLGLFLHFNWVLGLGRAKSVFSGWDLESLSLAIPAEVSVLTVFVVVFTFAIAIFKDIPDMEGDRQYNINTFTIKMGKPAVFDLSRWVLTVCYVGITLAGMLTLPNVNLGFLAVTHLAALGLMWFWSMKVNLEDKMEIAQFYQLIWKLFFLEYIIFPAACWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F435</accession>
    <name>A0A2G4F435_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Molecular chaperone DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56522">
        <property type="protein sequence ID" value="PHX56522"/>
        <property type="gene ID" value="CP500_005065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="9"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="319" mass="35392" checksum="E57BCC1A873E7BC3" modified="2018-01-31" version="1">MPTATDFKDYYTILGVSKTATPEEIKRAYRKLARKYHPDLNPGDKDAEAKFKDLNEANEVLSDPEKRPKYDRFGEHWNQPAYSEGPPSRGTNSGTVDFDQYGDFDSFIKDLLGRSRNGSQRRTNTTSGFDDYGGGFRSQAPAPDSEAAIALTFSEAFHGVQKRLQFDDETINVRIPAGAKPGSRIRLKGKGRASPFSQQRGDLYLTIEILAHSCFRFDGDDLVCDVPIRPDEAVLGAEISVPTPDGSVTMKVPQGVRSGQSLRLRGKGWTLQKGGRGDLLAKLLIVTPKDLSAIEQECYEKIQANTNFNPRAQLEEIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F494</accession>
    <name>A0A2G4F494_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pesticin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56566">
        <property type="protein sequence ID" value="PHX56566"/>
        <property type="gene ID" value="CP500_004785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031975">
        <property type="entry name" value="Pilin_GH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16734">
        <property type="entry name" value="Pilin_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="175" mass="18211" checksum="518C0E4AB7457300" modified="2018-01-31" version="1">MKTEFKAKFLQQINKRRQDQGFTLIELLVVIIIIGILSAIALPAFLNQANKAKQSEGKQYVASINKGQQAFYAENSKFSVDTTGTELGLGIKTATSNYEYDLSGGNTGTGGVVNVKPLVASLKGYGGSVALVTAGEAKTTTTIICQEGTTNTGNKGDLAAGATACSGTVPDPVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4A5</accession>
    <name>A0A2G4F4A5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56590">
        <property type="protein sequence ID" value="PHX56590"/>
        <property type="gene ID" value="CP500_004430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="80" mass="8820" checksum="881132C6DE295590" modified="2018-01-31" version="1">MIQKYFQNAMQAAHYEMLEDQVGFYGSIPGAAGVWATGSTLEECRSELLEVLEEWVLLGIAMGHELPEFDGAILKVESVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4K5</accession>
    <name>A0A2G4F4K5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidylprolyl isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56692">
        <property type="protein sequence ID" value="PHX56692"/>
        <property type="gene ID" value="CP500_004155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="2">
        <location>
            <begin position="111"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="250" mass="28611" checksum="B2C52151475FD4F6" modified="2018-01-31" version="1">MTGLFQIGDKLLQAQDMPSLLKRYQLMPQFLRGVIVDQAIAPFTCNDEESQSAVENFLVQHQLTAPEAREAWLRSQNMTLEELQEMVVRPLLIEKFKQATWRPKVDNYFLTRKASLDHVVYSLVRTKNPALANELYFRILEEEQSFAEVARDFSEGPESKSGGLLGPVPLSQPHPAISKLLSVSQPNQLWTPRPLAEWMVIIRLEKFMPAQLDESMRLHLINELFETWVNEQISQIGPLQPLSSASAIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Q7</accession>
    <name>A0A2G4F4Q7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Type I secretion system permease/ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_004150</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56691">
        <property type="protein sequence ID" value="PHX56691"/>
        <property type="gene ID" value="CP500_004150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="558"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="589"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="20"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="12">
        <location>
            <begin position="296"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="451"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="765"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="799"/>
            <end position="806"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX56691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1006" mass="111511" checksum="089CB135F25D069E" modified="2018-01-31" version="1">MTSSAVSLGQIQDFLAQTTPFDRLSETALTALVAKCQLLGYRTGQPLFEREKMPTQVAIIYEGQARLLGFDQRSQRHVSLRLVQSQEILGWAGLLRGVPCETAIASTDVIAIVIQTEDFLSVLEKQPKFGEAFREHCSLSEAFELLSLELQRQADATSNLKEITMQAWQDAKVVNLPNGNKKSQELAKELDSDRIWLVSSGVLGDFPTGSRLNIDSEAKSLKVEGRMGARLVGFREPPEPPPETAAADPLNGSINEGIEDLGKKRRIVFDDVTQAPPVPPEPRSDQPKDTKYPVFRGRGQIDGPLACFQMLSKYFGIKFRRDIIRKVLENQLKTAGSVTIQACGAIAQSIGLTPQLAQIPADAINRIKAPVMIKWKDTFAIVYSITEQELVVASPEEGLMRKRVPQFREIWGESGEVLLLQAPQQIDQKEQFSFWWFVPALMEHKTVFIEVLFASFFVQVFGLANPLISQIIIDEVLGKRNLDTLDVLGAFLLGVALFEGLLNGLRTFLFIDTSNRIDVKLSAEIIDHLLRLPQNYFDNRRVGDLVYKFSMMGQIREFMTGTALTVVLDAVFSVVYVAVMLSYSVQLTAVSLAVVPILALMIVLINPLVLRLIKQRNNRFSDAQSYLVEVVSGIQTVKAQNIELKSRWEWSSRYAKYITASFKTIITGTTAGTVSAFLNQVGNLAQLWVGAYLVLKNEMTLGQLIAFRIISGNVTGSLLRFVSVWQSFQEVSMSVDMLKDIVDTPTETSDEDRSNIPMPAIQGQVTYEEVSFRFLESGSLQLANVNLEFPPGSFVGIVGGSGSGKSTAMKLLQRLYPPLSGRIFVDGYDIAKVELYSLRSQLGVVLQDTLLFNCTVQENIALSNPDASTDEIVRAAKLAVAHDFIMGLPAGYNTIVGERGSSLSGGQRQRLAIARTILQNPKLLILDEATSALDYHSERQVCNNLAEAFSGRTVFFITHRLTTIQNADVIIMMDQGAVVEQGTHKELMGLKGRYYCLFQQQEASNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4W3</accession>
    <name>A0A2G4F4W3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_003565</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56812">
        <property type="protein sequence ID" value="PHX56812"/>
        <property type="gene ID" value="CP500_003565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="106"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="575" mass="63358" checksum="AE7FF1DB43418E8C" modified="2018-01-31" version="1">MSSQTPLHKAGRSPKAGIPLIQKTGGNLVLASGVTITMLLGMVLALSLAAVFIIDSPDPIVGFLIALAITLVFNIAAFFLSPWLMDFTQNWLYNTRWVSLAEIESKSPETAKVIQKVCQQHKLKQPRLGIIDDQNPTAFTYGSFPDSARLVVSEGLFTYLDDDEIATVYAHELGHIVHWDFAVMTLASTLVQITYLIYTTAQRLGRRGGEKVKDAADTIAGVAYLFYLFGTYLLLYLSRTREYFADHFAAETTGNPNALSRALVKIAYGILEEGQRATEPSRLLEGTRALGIYDAKAATSTGTAYRIASSPEKIGRVFLWDMFNPWAWWMELNSTHPLTGKRVRALSTYAEQLGLDIEFDMGRIIGEGHNLSKRKLYGNFVLDLLLYSAEILGLSVGFAIGISLSATNPMMMIACPLIGLGTGILLKTLVMFPKYSEAESLDVLTLMSDPYASPLRGQPAKLDGELIGRGDAGYAFGSDLKLQDKTGMIYLRYASRFGPIGNFLFGMKRVKSLIGMEVNALGWFRRGVAPWMDLIQLESDSGTTVNSYHRFWSFVMGVGAIAIGIVSLFLSYQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F562</accession>
    <name>A0A2G4F562_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56912">
        <property type="protein sequence ID" value="PHX56912"/>
        <property type="gene ID" value="CP500_002730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011964">
        <property type="entry name" value="YVTN_b-propeller_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02276">
        <property type="entry name" value="beta_rpt_yvtn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="60"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="541" mass="59423" checksum="8472E31F2642A6C0" modified="2018-01-31" version="1">MDGLAYLHLAETWETHPSQTQATNSTTHLNLASTPLLFFTLVLTIFNLVNPALAIRKGDSGSEVAELQKTLQDAGYFSRQPTGYYGSVTQDAVKKFQAENNLKVDGIVGPKTLSALKVKPEGNKSESAETISPNLDKVSPSPTENQNQIVPSPTATENPNQLEDSTKNQPRKPLFNNPFLPPFATENSTNQEPSKRTNKQQPKMGIRRQNINGNMTLKKTIYGNISPKSIVHSGSGLFFAQNMMYSHTITVYDRNFKLVKTIPDRVNLSKFGFSKFKGNSQGAPVEAAFTTDGKYAYVSNYQMYGSGFDNPGSDRCSPTAKHDQSFMYRINTETLKIEKVISVGAVPKFNAVSPDNRLVLTSNWCSWDLSVVDTQKNSEIERVKLGAYPRGIVVTPDSKTAYVAVMGSSDIARVNLTDFSVAWLRNIGNAPRHLVIDPNGKYLYATLNGEGNVAKINLNSGDVVDKISTGSQPRSMTISDDGKLIYVVNYSSNTVSKVRTSDLKVLKTVNVNSSPIGITYDSQTNQVWVACYSGSIMVFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5D4</accession>
    <name>A0A2G4F5D4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HEPN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56994">
        <property type="protein sequence ID" value="PHX56994"/>
        <property type="gene ID" value="CP500_002600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007842">
        <property type="entry name" value="HEPN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05168">
        <property type="entry name" value="HEPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN" evidence="1">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14936" checksum="DFB3528BF82AA7EE" modified="2018-01-31" version="1">MTPEQQRLLDKANRSLQAARELNNTGFPEFATSRAYYSMFYIATAFLEAEGLSYSRHSAVIAAFGERFARTNRVPVELHRYLIDAERARLRADYNVDPNITETDAEQLISRTEYFLNFAIANIDSLPPPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5F4</accession>
    <name>A0A2G4F5F4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56990">
        <property type="protein sequence ID" value="PHX56990"/>
        <property type="gene ID" value="CP500_002575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040699">
        <property type="entry name" value="XPB_DRD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18458">
        <property type="entry name" value="XPB_DRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="88"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="323"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="513" mass="57883" checksum="08EA7228589115E5" modified="2018-01-31" version="1">MSRTPTLTFDRGTLLLHPPPKGRDWVDFATWDDRVEKFRIRAIHYRPLVECLQAGCIHFTDEARAYELLELVPSVEMQPYPHQEQALAAWRQAGSQGVVVLPTASGKTYLAQLAMQVTNRSTLIVVPTLDLMHQWYANLTAAFPKIEIGLLGGGSRDKTPILVATYDSASIHAETLGNKYGLLVFDECHHLPTDFFRVISEYAIAPFRLGLTATPDRTDGRHSDLHFLIGPTVFSRRPEDLAGDALAEHKIVQIMVKLSKEEGDRYGELMAIRNDFLKHSNIKISTIEGWKKFIMASARSPLGRGAMLAHNQAKAIALCTEGKLRILAEILEKHYPQRTLIFTADNATVYRISQEFLIPTITHQTPVKERHEILQKFRSGEYKTLVASHVLNEGVDVPDARIAIILSGTGSEREYIQRLGRVLRKSSDVNKLAILYEVVTENTSEERTSQRRRGGMQVEKPQLKSIIEPPEPEHQQLEIFKPTPIYGVNRETTQRAAESPQKWGENNDGENKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5F8</accession>
    <name>A0A2G4F5F8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FtsK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002445</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56965">
        <property type="protein sequence ID" value="PHX56965"/>
        <property type="gene ID" value="CP500_002445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="444"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="461"/>
            <end position="468"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="683" mass="77512" checksum="BF83ABE1ECDB216E" modified="2018-01-31" version="1">MINKYHTLYFAISPKPHIQTNERSHQIKKELQKTQDQIILSLIRLGTNLTISLRYIYDPNQSPKLKTYLLINHPHNTQTAEDSEQILSLLTKGKLSQFFTLTPQPNLTPFQNLDWVQTIGEILKHEEFIAPQNYYLPHLFEANQTNDMSAVCDVIHRLDSKLILEITLQTYDNPNQKSLWVNAINQMLAQLDKVNANTSGIKDNILSVTSALYQKYQQSYPNSDLFQYSIKALAENRADAFPVLDALIHEAIKETPHGKRCRIIQVSKNQPGFSESLEATKNVNISSAIEWEGWHKNNSQMSIANAIQPEKKGIRKFGGDSVSRPDKPSFNDQNQPPMIGGVNSEQNSNLPQLYNTVSDGSGLAKLSSTPPPSRMVDLKPLHRLATAQEISGFFRIAVPPVNNTTSFEETVKMLPEILPIEDVIKKYGHLINEDTYLVGVEESGEPCLSNFEDIAHRLVAGVPKSGKTNFINSMIYQFLYASHKIQAEREIYIADFKEGLDYYRITRRYPNVKLVTEFDEFASLLNSLVQKYKQRVNALKTQDVESLAQLRAKCNTQDHRILLFIDEAASIVNAERSIKANIYRDLETLVLKSRVADINIFYCTQQPADTNVTPTQILYNLDERVIFRVQSSISTRLLDDDRAGSLPVNPKGRAIYRGLEAEIKLIATPYVPKAIWTKDSLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5I8</accession>
    <name>A0A2G4F5I8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56971">
        <property type="protein sequence ID" value="PHX56971"/>
        <property type="gene ID" value="CP500_002475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9771" checksum="71F3213EBC01899A" modified="2018-01-31" version="1">MAKKIWIVYKTESMSAPGWEERQLMPRGGLTNILWENWTWEENPNFLLWILRSELWFVTVFINQLHLTGKRYNKASLSIRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F682</accession>
    <name>A0A2G4F682_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ATP-dependent Clp protease ATP-binding subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_001095</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57266">
        <property type="protein sequence ID" value="PHX57266"/>
        <property type="gene ID" value="CP500_001095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="13">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="12">
        <location>
            <begin position="416"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX57266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="821" mass="90997" checksum="D76C0ED29FC9F627" modified="2018-01-31" version="1">MFERFTEQAIKAIMLAQEEARRLGHNFVGTEQILLGLVGEGTGIAAKVLLEMGLNLKEARNEIENIIGRGSGFLPPEIPFTPRVKRIFETALNEARQLGHNYIGTEHILLGLIQDDEGVAAKVLQNLGIDRSRVRTQVIRAVGEVAAVSGGRQSSDRKIPTLEEFGTNLTKLAAQGKLDPVVGRENEIERVIQVLGRRTKNNPVLVGEPGVGKTALAEGLAQRIVNRNVPEILEDKQVISLDMGSLIAGTKFRGEFEERLTKIMAEIRAAGNIILVIDEIHTLVGAGAIQGSMDASNMLKPALARGELQCVGATTLDEYRKYIERDAALERRFQPIKVGEPSVAETIEILYGLRSAYEQHHKLTISDAALEAAATLSDRYINDRFLPDKAIDLIDEAGSRVHVLNSQTPPEVKELKKRLPAVTKEKDIAVREQDFEKASKLRDRELAIEAEIAEATINKSQVRISPIVTEEDIAHIVANWTGVPVSKLTESESELLLHMEDTLHQRLIGQEEAVTAVSKAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKALATYFFGSEDAMIRLDMSEYMERHTVSKLIGSPPGYVGYDEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNMMLQILEDGRLTDAKGRTVDFKNTLLIMTSNLGSRVIEKGGGGLGFEFTEDAADGQYNRVRNLVNEELKQFFRPEFLNRLDEIIVFRQLNKEEVKQIADIMLQQLFTRLTEQDITLSVTEAFKELLVKEGYNPSYGARPLRRAIMRLLEDVLAEEMLSGKLKEGQSAIVDVDENGVVKVLPGDSSEPKLPELALSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F692</accession>
    <name>A0A2G4F692_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX57007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57007">
        <property type="protein sequence ID" value="PHX57007"/>
        <property type="gene ID" value="CP500_002410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="179" mass="19907" checksum="A3ACD9CBB1E54396" modified="2018-01-31" version="1">MVMAAVLSENVSLEDFIASPPDDMEWVDGQIAEKNGMTVKHSRIQSRLDRYWGNYKDSSGQGGEVYTEVPCRTNLRVRRPDVAYLTSELVAQYGDVPTFPQSPLLVAEIVSPTDIAEDIFLKAQEYLDSGCLEVWIVFPESRWIMIVTQTQKLAFNSGAIVSTQLVLLGFSVAVDELLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F698</accession>
    <name>A0A2G4F698_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CopG family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57276">
        <property type="protein sequence ID" value="PHX57276"/>
        <property type="gene ID" value="CP500_001150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="84" mass="9373" checksum="A110A8332EBC447F" modified="2018-01-31" version="1">MSTYSEVLSQAQSLTPDEQQQLLEVLSALMRDRLTTQTQGKRSEIDAALIEMAQDPEYQAQVLQMEAEFAVASWEALQLGESPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6A4</accession>
    <name>A0A2G4F6A4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor G</fullName>
            <shortName evidence="6">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fusA</name>
        <name evidence="8" type="ORF">CP500_001205</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57286">
        <property type="protein sequence ID" value="PHX57286"/>
        <property type="gene ID" value="CP500_001205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="6"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="15"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="79"/>
            <end position="83"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="695" mass="77111" checksum="F6FAB09BA3C5E07D" modified="2018-01-31" version="1">MMKDLTRYRNIGIFAHVDAGKTTTTERILKLTGKIHKIGEVHEGAATTDFMEQEQERGITIQSAATTCFWNEHQLNIIDTPGHVDFTIEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYANDSKVARVIYINKLDRTGADFYRVVKQVDKILAAKPMVMVLPIGIEEKFCGVVDLLTRKAWIWDDSGDPMNYEIKDVPADMVDDVETWREQLIELAVEQDDTLMEQYLEGNEPSIDDIKRCIRKGTRDRAFFPTYCGSSFKNKGVQLVLDAVVDYLPNPMEVTPQPEVDLDGNETGEFAIVDPSRPLRALAFKIMDDRYGALTFTRLYSGTLSKGDTILNTATGKTERISRLVEMHANSREEIDSAQAGDIVAIVGMKNVRTGHTICDPKNPATLEPMVFPEPVISISVRPKQKGGEEKMGAALTKMVQEDPSFHMVTDQESGEMILKGMGELHLDIKVDILKRTHGIEVEVGEPQVAYRESITKRLEDDYTHKKQSGGSGQFAKIGYVIEPGEPGSGFIFESKVTGGSVPREYWPAVEKGFESCVDKGVLAGFPCLDLKFTLLEGGFHAVDSSAMAFEIAAKAAYRQSIPKAGPQLLEPIMNVDVFTPDDYMGDVIGDLNRRRGMMKAQETSQTGARIKADVPLSEMFGYISDLRTMTSGRGQFSMSFSHYSPCPSNIAEEVIKQAKERQAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6D0</accession>
    <name>A0A2G4F6D0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57251">
        <property type="protein sequence ID" value="PHX57251"/>
        <property type="gene ID" value="CP500_001010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025591">
        <property type="entry name" value="RloB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13707">
        <property type="entry name" value="RloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="210" mass="24858" checksum="231ACC2E5B086001" modified="2018-01-31" version="1">MSKKSSSRSKIDYYNRKDKTRRWFLIVCEGEKTEPNYFKKFPVDPRVINLDIKGEGKNTRSLVEKAIELKNKDKYDENDRFWCVFDRDINGRNSNDAQNFNAAMTLAKNNGIKVAYSNDAFELWYLLHFHFYNTGISRQNYQQKLTKLLGHEYQKNSEKIYEELKDRQQDAIKHAKRLLQKYDVSNPETDNPSTTVHLLVEELNSFIPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6G9</accession>
    <name>A0A2G4F6G9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57291">
        <property type="protein sequence ID" value="PHX57291"/>
        <property type="gene ID" value="CP500_000900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="415" mass="45058" checksum="94D71FEC00F44C99" modified="2018-01-31" version="1">MLKITVIGGGAAGFFSAITCAQTYPQARVTLLEAGRQVLAKVRISGGGRCNATHACFDPAILVQNYPRGGKALRGAFTRFQPRDTVEWFASHSVILKTEADGRMFPVTDDSATIVNCLIRAAEDAGVQIRTGDAVVSVKKLTSDIGEGGHGGTAPTFEIVFKSGEQLKCDRLILATGSNPSGFKWAKDLGHTVEPPVPSLFTFNISDRRIQDLAGVSVANAKVKLPAAKLEQSGPLLITHWGLSGPAVLKLSAWGARFLHDRHYQTSVLINWLPQYNPEVLRQQLLGVKSQLSQRLVVSSCPFPIPRRLWERLTSAIGIDEPKRWADIPNKTLDKLLQELVQGEYQIAGKGAFKEEFVTCGGVNLKEVDFKTMESRHCPGLYFAGEILDIDGVTGGFNFQSAWTTAWLAGIAIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6M7</accession>
    <name>A0A2G4F6M7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_000470</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57444">
        <property type="protein sequence ID" value="PHX57444"/>
        <property type="gene ID" value="CP500_000470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="79"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="386" mass="42835" checksum="AA90A541CA956501" modified="2018-01-31" version="1">MIKLLRDDRFWKIAGQAIALISVIAVIAILWDNLTANYAQLGINFGFDFLNSQASFDIGEKVIDYNPENSYKQAYWVGLFNSLRVMIIGIVLATIAGLTVGIARLSNNWLLRTLAGLYVEVIRNTPLLLQLFFWYFAVFIAFPKLEENPQMSGPVYLTNRGIALPWLATLPGFEIWLILLAVGCLGAIGLWLWRDRVMLEQAQPGRHLFWALGAIGLSAILALIITRNLPFRLDIPRLTADLQLEGGLQLSPEFAALVTGLSLYTGSYIAEIVRAGIQSVPKGQSEAAKSLGLQSGTMMRLVILPQALRVIIPPLTSQYLNLAKNSSLAVAIAYPDVYFVVASPTLNQTGRAIEAMLIIMVTYLTISLIISLFMNWYNQSVQLKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6R4</accession>
    <name>A0A2G4F6R4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">purK</name>
        <name evidence="7" type="ORF">CP500_000140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57450">
        <property type="protein sequence ID" value="PHX57450"/>
        <property type="gene ID" value="CP500_000140"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="118"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="184"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="269"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="42598" checksum="FB358E00DCEE85C2" modified="2018-01-31" version="1">MKFTQATAITSTKIQRVGVVGGGQLAWMMGAAASRLGMELVVQTPNLTDPATAIAADTILAAIDDVNATAELATRCDVITFENEFVDLDGLRTLEEQGVLFQPSLSSLDPLLDKYIQRCYLQDLGLPTPRFWEWDGSQDLPLDFPLVIKVRRHGYDGQGTFVVKDAASFESICVKLQGVALLVEEFVPFDRELAAIAARSANGEIAIYPIVETQQQNQVCRLVIAPADISLEVKAEAEAIARTLLNSLQAVGVFGIELFLTSDNQLLVNEIAPRTHNSGHFTIDACKTSQFEQHLRAVCQLPLGNCDLNSAGAVMVNLLGYESAESDYLEKRKQLAQIPGSFVHWYGKKESRPGRKLGHVTVLLDREAVDQGRSQVLAIAQTIESIWGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6S3</accession>
    <name>A0A2G4F6S3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="2 7">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purD</name>
        <name evidence="10" type="ORF">CP500_000135</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GARS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="2 7"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57449">
        <property type="protein sequence ID" value="PHX57449"/>
        <property type="gene ID" value="CP500_000135"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="109"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="428" mass="45731" checksum="A265B90556B63F69" modified="2018-01-31" version="1">MKVLVVGNGGREHAIAKKLLESTRIKQVFCVPGNGGTATTEGCQNLPLNIDDFQGMERFVMVNNISLVIVGPELPLSLGIVDYFQQKKLMAFGPTQAGAQIESSKSWAKELMLEAGIPTPKAAVFTNPEAAKAYVVEQGTPIVIKADGLASGKGVTVATTVKMALSAINTIFRGAFGTDNIRVVVEEYVTGQEVSILALTDGITVEPLLPAQDHKAIGEGDKGANTGGMGAYAPAPIITPELMERIQTEILEPTLVALQKRQIDYRGVLYAGLMITAEGEPQVLEFNCRFGDPETQAVLSLLETPLEDLLLACCQQRLGEFSSNIRWKEGASVCVVLASGGYPGSYQKGKTITGIEEAEAKGVEVFHAGTQLKQQQLVSDGGRVLGVTAVGETLQQAIAKAYEAVDCIEFEGVYCRRDIGRRALVDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUM1</accession>
    <name>A0A2G4EUM1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_023155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000270">
        <property type="protein sequence ID" value="PHX53130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53130">
        <property type="protein sequence ID" value="PHX53130"/>
        <property type="gene ID" value="CP500_023155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7701" checksum="6D8C28F929D82092" modified="2018-01-31" version="1">MERSKIIAIITGAFSIVLALGYLLLVTLLDFRGEMLPAPQSQLPVSLQLQQLVTANQTLRAPRIYTQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUP9</accession>
    <name>A0A2G4EUP9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000229">
        <property type="protein sequence ID" value="PHX53255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53255">
        <property type="protein sequence ID" value="PHX53255"/>
        <property type="gene ID" value="CP500_022475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="10"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="325" mass="36342" checksum="59150B0D321B6F8F" modified="2018-01-31" version="1">MPNAQCPKISAIICTHNRHSYLGAAIDSLLAQDFPDNFEIVVVDNASSDYPSPDSSKTRTREVVEARLSDCRLKYVWEPELGLSVARNTGARVAESEILAYLDDDAVAESNWLRVLHSAYQTNQKLAVAGGKVKLLWPSGFSPPEWLSPGLAENLGAYDLGESWVYVTAAGLTPRGVNYSIRRTFLAQIGGFDVKLGRVGQKLLSNEELRATELALELGWQVIYLPEALVLHNVAPSRLHKAWFVERGWWQGISECYREQLCDRAGIVQLWRGGERMLRGVYKSFKYIRDPALRFENLVFAWGQIGYLSAAISGLIFAPKSTRKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUZ4</accession>
    <name>A0A2G4EUZ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53354">
        <property type="protein sequence ID" value="PHX53354"/>
        <property type="gene ID" value="CP500_021960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="117" mass="12930" checksum="C13C17BD8182AE8A" modified="2018-01-31" version="1">MPKSLPYHPFLIESLRKNPALAAAYITATLEEEEPEPELLKRAISDVVEALGQPKMTPEQYELHLKKLDKLLSKEGSDAIYSLGSWLKALGLKLTVAVCTDTEDNNLNAEIPAQLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV08</accession>
    <name>A0A2G4EV08_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000221">
        <property type="protein sequence ID" value="PHX53296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53296">
        <property type="protein sequence ID" value="PHX53296"/>
        <property type="gene ID" value="CP500_022280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7336" checksum="D51A6A483BF1CCDE" modified="2018-01-31" version="1">MTHYSLSQLGEVMGNGASGIGHRASGIGHWVMGHRALGIGHRALPITNYLLPITNSRSDLIFLRKAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV94</accession>
    <name>A0A2G4EV94_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000195">
        <property type="protein sequence ID" value="PHX53454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53454">
        <property type="protein sequence ID" value="PHX53454"/>
        <property type="gene ID" value="CP500_021425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="217" mass="24675" checksum="1DDB1C0A2BE83D4E" modified="2018-01-31" version="1" fragment="single">MNQQHQQNNQEYITFLDEVWQATSDSNGDAKIIYPILAANQDKLNRTLVAQYQNWANNILSQAAPAQTRNIAVDFVNFSNLIKDFPLGNRASNLDIAIIGYELALTIFTRADFPQEWATTQNNLAIAYSNKITGNKAENLDEAIRCYQLALEVRTRADFPQDWAMTQNNLASAYLYKITGNKAENLDEAIRCYQLALEVRTRADFPQDWAMTQNNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVH6</accession>
    <name>A0A2G4EVH6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000181">
        <property type="protein sequence ID" value="PHX53541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53541">
        <property type="protein sequence ID" value="PHX53541"/>
        <property type="gene ID" value="CP500_020965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="205" mass="23136" checksum="EA63C58CE2D44BFD" modified="2018-01-31" version="1">MRIFNQSPPSETETKKRILQAAQKLFARSGYDGTTTRELATAAGVAEGTLFRHFDNKKAILIEVATEGWVELLTDLLTELSEMGSYKAVAQVMRRRMLNIRENSDMMRVCFLEAQFHPDLRDRIQLEVIGKMSEVAEAFFETAMEKGVYRKMNPKIVAQVFLGMFAVAGFSQNTIMEPNASPQQMQEMAEGLADIFLNGVLIKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVI1</accession>
    <name>A0A2G4EVI1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_020895</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000179">
        <property type="protein sequence ID" value="PHX53552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245911">
        <property type="entry name" value="M.Tbo703ORF20895P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53552">
        <property type="protein sequence ID" value="PHX53552"/>
        <property type="gene ID" value="CP500_020895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="6">
        <location>
            <begin position="54"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="179"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="311" mass="35939" checksum="9878B6453DF25453" modified="2018-01-31" version="1">MQLSLDVVSDTQQIREQELNPLTQGFKLQYSHPHGQLYQGNSIDWLKSIESESVNLIFADPPYNIKKADWDRFDSQEQYIEWSLQWVSEASRILKSTGSLYICGFSEILADLKRPASKYFKSCRWLIWHYKNKANLGSDWGRSHESIIHFRKSDCVKLNIDDVRISYGAHTLKYPSHPQAKTSAYGKGATKKRDNWTPNPNGAKPKDVIEIPTTCNGMGETTPHPTQKPEELLRKFVLASSKVGDLVIDPFSGSGTTLVVAEQLNRYWMGCDLNMEYNDWAFRRIESVRRMTKEEWISLDRKNAERRESIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVJ0</accession>
    <name>A0A2G4EVJ0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyruvate formate-lyase-activating enzyme</fullName>
            <ecNumber evidence="9">1.97.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pflA</name>
        <name evidence="11" type="ORF">CP500_021450</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl-L-methionine = 5'-deoxyadenosine + glycin-2-yl radical-[formate C-acetyltransferase] + H(+) + L-methionine + semiquinone [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:19225"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12190"/>
            <dbReference type="Rhea" id="RHEA-COMP:12191"/>
            <dbReference type="Rhea" id="RHEA-COMP:14480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29947"/>
            <dbReference type="ChEBI" id="CHEBI:32722"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:140311"/>
            <dbReference type="EC" id="1.97.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.97.1.4" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000196">
        <property type="protein sequence ID" value="PHX53450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53450">
        <property type="protein sequence ID" value="PHX53450"/>
        <property type="gene ID" value="CP500_021450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012839">
        <property type="entry name" value="Organic_radical_activase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012838">
        <property type="entry name" value="PFL1_activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000371">
        <property type="entry name" value="PFL_act_enz"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02493">
        <property type="entry name" value="PFLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="16"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="246" mass="27718" checksum="44C69DB41EFB4769" modified="2018-01-31" version="1">MSGIGRIHSIETFGTVDGPGIRFIVFTQGCPLRCLYCHNPDCRNAHDGKEVTVDYLINEIKKCKSYLRKGGVTVSGGEPLMQPEFTREIFDRCHQLGLHTALDTSGYCGLEIAKPVLEMTDLVLLDIKSYIPELYYKVTNVSIEPTLAMAKYLSEIDKPTWIRFVLVPHLTDNIENVEKLADFIATLKNVERLEVLPFHKMGEYKWEQLGLGYELKDTPPASAEQVQQIVDIFRDRGIEAIGAIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVJ3</accession>
    <name>A0A2G4EVJ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000191">
        <property type="protein sequence ID" value="PHX53486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53486">
        <property type="protein sequence ID" value="PHX53486"/>
        <property type="gene ID" value="CP500_021270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="10010" checksum="F0D4BEB5D30A6771" modified="2018-01-31" version="1">MMEDDDQKDSRHASAQSFFESLDELFDYIEASSNEAAQPQSPKVEPKSSSPPKKARPAKINLSDFEDAIADLEQFIQKKHQKRPESNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVM4</accession>
    <name>A0A2G4EVM4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA-directed RNA polymerase subunit gamma</fullName>
            <shortName evidence="11">RNAP subunit gamma</shortName>
            <ecNumber evidence="11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">RNA polymerase subunit gamma</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Transcriptase subunit gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoC1</name>
        <name evidence="14" type="ORF">CP500_021100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11 12">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11 12">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 Zn(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000185">
        <property type="protein sequence ID" value="PHX53516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53516">
        <property type="protein sequence ID" value="PHX53516"/>
        <property type="gene ID" value="CP500_021100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01323">
        <property type="entry name" value="RNApol_bact_RpoC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012755">
        <property type="entry name" value="DNA-dir_RpoC1_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034678">
        <property type="entry name" value="RNApol_RpoC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02387">
        <property type="entry name" value="rpoC1_cyan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RPOLA_N" evidence="13">
        <location>
            <begin position="241"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX53516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="624" mass="70668" checksum="F73642373292C628" modified="2018-01-31" version="1">MAKIEQRFDYVKIGLASPERIRLWGERTLPNGQITGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVAHVWYLKGIPSYMAILLDMPLRDVEQIVYFNAYVVLNAGNADKLEYKQLLTEDAWLEIEDELYSEDSTLTGVEVGIGAEALQVLLENIPLESEAEKLREDIANAKGQKRAKLIKRLRVIDNFIATGSHPDWMVLSVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQDILAPEIIIRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKIHQCGLPREMAIELFQPFVIHRLIRQGLVNNIKAAKKMIQRNDPGVWEVLQEVIEGHPVMLNRAPTLHRLGIQAFEPILVDGRAIQLHPLVCPAFNADFDGDQMAVHVPLSLESQAEARLLMLACNNIMSPATGRPIVAPSQDMVLGCYYLTADNPDGQKGAGKFFANLDDVVVAYEQKIVDLHSLVWVRFQGEIDSGEPEGEPSRVERSSNGFVTKEYKFRRVREDERGNVINQYIRTTAGRVIYHQTILSVINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVS5</accession>
    <name>A0A2G4EVS5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxysome assembly protein CcmM</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Carbon dioxide concentrating mechanism protein CcmM</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_020260</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Carboxysome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the gamma-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000165">
        <property type="protein sequence ID" value="PHX53662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53662">
        <property type="protein sequence ID" value="PHX53662"/>
        <property type="gene ID" value="CP500_020260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017156">
        <property type="entry name" value="CcmM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000894">
        <property type="entry name" value="RuBisCO_ssu_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036385">
        <property type="entry name" value="RuBisCO_ssu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00101">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037250">
        <property type="entry name" value="CcmM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00961">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55239">
        <property type="entry name" value="SSF55239"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RuBisCO_small" evidence="10">
        <location>
            <begin position="218"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="RuBisCO_small" evidence="10">
        <location>
            <begin position="338"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="RuBisCO_small" evidence="10">
        <location>
            <begin position="450"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="308"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="312"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="194"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037250-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037250-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037250-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="544" mass="58826" checksum="1E78CE7083E0AC49" modified="2018-01-31" version="1">MAVRSVAAPPTPWSKNLAEPKIHETAYVHSFSNIIGDVHIGSKVLIAPGTSIRADEGTPFYIGEGTNIQDGVVIHGLEQGRVTGDDDNSYSVWVGKNTSLTHMSLIHGPAYVGDDCFIGFRSTVFNARVGNGCIVMMHVLIQDVEIPPGKYIPSGAVITNQQQADRLPDVLDSDVKFATHVIGVNDALRTGYRCADNIACLAPIRNELSKHSDMTPITYSTQSTSQLSNSLVDSVRNLLAQGYSVGAEHADQRRFRTGSWRTCGPISSTRESEVINALSACMSEHQGEYVRLIGIDTKAKRRVLEEIVQRPGDNGSNGSNGATTHQSNGKVAQASHQNGAAASNGKLTGDFVGTVRSLLAQGYKVGTEHADQRRFRTSSWQSGASVQGRNESEAIATLEAVMRQYPGEYVRLIGIDPKAKRRVVEEIIQRPDGPVVQSAQPAATGSYKATSTTTNSSGVLSGKTIDQIRNLLSQGYKIGTEHADARRFRTGSWNSCAPIASNRESEVISALESCLKEHSGDYVRLLGIDSKAKRRVLEEIIQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW08</accession>
    <name>A0A2G4EW08_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53711">
        <property type="protein sequence ID" value="PHX53711"/>
        <property type="gene ID" value="CP500_020090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="14"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="24529" checksum="881ED0D18645D19A" modified="2018-01-31" version="1">MFSSPLFDNRADAGQKLAAAVKAEIEKLNLTASDDVKPIVYALPRGGLPVAVPIARLLGCPLDVVVAKKITRPDNLEYAIGAATADGEVVWQQKPRNLPFQTLALQQALDRAQSLLADLSPGRPNVSATGALAILVDDGIATGMTMAVAAKALRAQQLGALWICVPVAPQDLLEFLEEMSDRAIVLETPDPFYSVSRFYAEFPQVETEVALACLMQQTEWRSSVKLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW19</accession>
    <name>A0A2G4EW19_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000206">
        <property type="protein sequence ID" value="PHX53377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53377">
        <property type="protein sequence ID" value="PHX53377"/>
        <property type="gene ID" value="CP500_021815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14264" checksum="91618378EFA5DB15" modified="2018-01-31" version="1">MLSQPIFGDRSLTQAFYQAVIDRFDDPLSLSTQALLRECTLGFAPSPEGVKTFFLIAPTLEAAEQLIDKIESILERVGELMAGVGQVALCVMPAGSEALETVDPQNLEKVPTDCLACKFFSIMCDCETADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW31</accession>
    <name>A0A2G4EW31_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53729">
        <property type="protein sequence ID" value="PHX53729"/>
        <property type="gene ID" value="CP500_019905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10454" checksum="92F2900167507F50" modified="2018-01-31" version="1">MRRRAIGCLLNFLKVKSWRILSRIRNREWGIGHWALGIGHWAWGIGHWALGIGHWALGIGHWVLFISITPTRGRARGHRPYKRRETRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW48</accession>
    <name>A0A2G4EW48_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4160 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53407">
        <property type="protein sequence ID" value="PHX53407"/>
        <property type="gene ID" value="CP500_021690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025427">
        <property type="entry name" value="DUF4160"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13711">
        <property type="entry name" value="DUF4160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="9339" checksum="450B685194BF813F" modified="2018-01-31" version="1">MPTVLQVGPYSFIFFSSDRGEPAHIHVKRDRQLAKFWMNPVSLEKNRGFKEHELNQIARLVEEYEQTLLEAWHDYFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW92</accession>
    <name>A0A2G4EW92_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc ribbon domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000154">
        <property type="protein sequence ID" value="PHX53791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53791">
        <property type="protein sequence ID" value="PHX53791"/>
        <property type="gene ID" value="CP500_019570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="13417" checksum="26166304E33BDA9B" modified="2018-01-31" version="1">MPDCPRCHQPVDTQSIACPHCKTALKAFGHPGIPVYRSKPQEFLCTTCTYHEDDTCNYPQRPFAQECTLYHNKAEPIVPPTTRYISGGWRQSVKSWCQRHLVWFALLGLIVISIALSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWF8</accession>
    <name>A0A2G4EWF8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-deoxy-7-phosphoheptulonate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aroF</name>
        <name evidence="3" type="ORF">CP500_019105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000145">
        <property type="protein sequence ID" value="PHX53875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53875">
        <property type="protein sequence ID" value="PHX53875"/>
        <property type="gene ID" value="CP500_019105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041071">
        <property type="entry name" value="DAHP_snth_FXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006268">
        <property type="entry name" value="DAHP_syn_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18152">
        <property type="entry name" value="DAHP_snth_FXD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01361">
        <property type="entry name" value="DAHP_synth_Bsub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAHP_snth_FXD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="DAHP_synth_1" evidence="1">
        <location>
            <begin position="95"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="352" mass="38344" checksum="BA588E3DAF733D9F" modified="2018-01-31" version="1">MIIVMKAGTPEAEIDRLDQELRTNWGLEPEKIVGRYKVVIGLVGDTADLEPMHLREMSTWIEEVLRVEKPYKRACLEYRQGEPSAVEVSTPLGIVTIGLNHPIAIVAGPCSVENEEMIVETAMRVKAAGAHFLRGGAYKPRTSPYAFQGHGESALALLAAAREASGLGIITEVMDAADLSAIVEVADVVQVGARNMQNFSLLKKVGAQDKPVLLKRGISATIEEWLMAAEYIMAAGNPNVILCERGIRGYDRQYTRNTLDLSAVPVLRTLTHLPIMVDPSHGTGWSQFVPSMAFAAIASGTDSLMIEVHPNPKKALSDGPQSLTPDQFDKLMEELAVIGKVMKRWPQVPALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWR3</accession>
    <name>A0A2G4EWR3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53985">
        <property type="protein sequence ID" value="PHX53985"/>
        <property type="gene ID" value="CP500_018605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="450" mass="51232" checksum="2234E8F0B06DD0FA" modified="2018-01-31" version="1">MKDSKNINKGNNVLSIIAINLAIVFIGMESLSLAFYFITQNQFFYTRSKTQEQVVEDIERIGIRLDDSIVERLHPFFGYVMKQGSFANKRINLKVNRQGFFSQQEYPFTKTSKNQFIVGIFGGSVANNLAVDEYESRMLSRKLKSYPEFANKEIVVLNFANGGYKQPQQLLVLNYFLALGQEFDMVVNIDGFNEVALANLNNKSKLDLAMPSVQHVQPLTDLANDNLSPEVMTSIVKISENKKQLRTTIAQLQNCKLALCNAVTSIKVRLLLKDYQQELVKYDKQVKQSKTDPKNSGTVYIPKSDTVLDDAAAFSKMVSMWYESSVMMNQVLSIRNIPYFQFVQPNQYYPTKRVFTQKEKEFTIVKDSPYIEGVTKGYPLLLSKVDDLQKAGVSVFSGVNILDNTKETVYKDSCCHYNLVGQELFANYISSSIIKVFRESPKSNKPQKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWV8</accession>
    <name>A0A2G4EWV8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54009">
        <property type="protein sequence ID" value="PHX54009"/>
        <property type="gene ID" value="CP500_018395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="21424" checksum="3E0EBA30280CB028" modified="2018-01-31" version="1">MENISILEQAANSNLKPSSNEVVIALIETEKNAKKNKTRYSFEQLIGNWQLCFITGTKKSRKKAGIVLGAGRYIPQWIAKIQIAYAAEPVAEGEENSETGRVENSVKVGTMELTLSGPTKFLPNNILAFDFTRITVKLLGKTVYQGYIRGGESRETEFLSLSVGKQAFFAYFLVEDRIIAARGRGGGLALWGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX11</accession>
    <name>A0A2G4EX11_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53980">
        <property type="protein sequence ID" value="PHX53980"/>
        <property type="gene ID" value="CP500_018570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="12320" checksum="4FE3024D68F2374B" modified="2018-01-31" version="1">MTSFNQTETFDTDNEGQVDIVAELADWDDDEVAHVVTAAVDLNSDEIFETVFIRNEENTFDVVYDTNQDGIPDAVDYGSNGSIDIVADLNNDDQINAQDVSIASAAIDALQDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX72</accession>
    <name>A0A2G4EX72_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000122">
        <property type="protein sequence ID" value="PHX54133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54133">
        <property type="protein sequence ID" value="PHX54133"/>
        <property type="gene ID" value="CP500_017775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="90" mass="10085" checksum="8143B9C4B2292EF4" modified="2018-01-31" version="1">MTAFQLSLFPNEPPTPLDSLNKKRRVKLQSQPTVIEQSCTTHRAAQLLEVSTTTLYRARKEGKPYEKGAWTATAIGANAWTVIYNPLNSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXE7</accession>
    <name>A0A2G4EXE7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54214">
        <property type="protein sequence ID" value="PHX54214"/>
        <property type="gene ID" value="CP500_017250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7594" checksum="EF542EFB6B50938E" modified="2018-01-31" version="1">MASIRELHRQLVNKERSAVEITQEALDRITQLEPKLKSFLCVTAVRATAPIKLRLKWLVNYDSWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXI8</accession>
    <name>A0A2G4EXI8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">map</name>
        <name evidence="6" type="ORF">CP500_017130</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54254">
        <property type="protein sequence ID" value="PHX54254"/>
        <property type="gene ID" value="CP500_017130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="5">
        <location>
            <begin position="34"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="275" mass="30255" checksum="CD02B8AA3FE1359E" modified="2018-01-31" version="1">MNIFSSLLSGTTKEPQVKKQRRGIEIKSEREIEIMRQAAKIVATVLKEISEMVKPGMTTADLDTYAEKRIRAMGATPSFKGYHGFTGSICSSINNEVVHGIPSRKKVIRAGDVLKVDTGAYYQGFHGDSCITIAVVEVTPESAKLIRVAEEALYKGIEQVRAGAYLLDLAGAIEDHVKSNGFSIVEEFTGHGVGRNLHEEPSVFNFRTREMPNVKLRSGMTLAIEPIVNAGSKYTRTLADKWTAVTIDNAMSAQFEHTVLVTDTGYEILTDRTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXL1</accession>
    <name>A0A2G4EXL1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium-transporting ATPase, P-type 1</fullName>
            <ecNumber evidence="5">7.2.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Mg(2+) transport ATPase, P-type 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">mgtA</name>
        <name evidence="17" type="ORF">CP500_017035</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Mediates magnesium influx to the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + Mg(2+)(out) = ADP + H(+) + Mg(2+)(in) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10260"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.14" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54275">
        <property type="protein sequence ID" value="PHX54275"/>
        <property type="gene ID" value="CP500_017035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015444">
        <property type="term" value="F:P-type magnesium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02077">
        <property type="entry name" value="P-type_ATPase_Mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006415">
        <property type="entry name" value="P-type_ATPase_IIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01836">
        <property type="entry name" value="MGATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01524">
        <property type="entry name" value="ATPase-IIIB_Mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="90"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="765"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="800"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="830"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="862"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="16">
        <location>
            <begin position="33"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX54275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="895" mass="98449" checksum="03F7E0523ACBD984" modified="2018-01-31" version="1">MKTLNKTPKASKKPQTDSNQSVDSSDSSKALIDIAQRDVDGVLHLFDTELDGLTETEAKRRLSKSGLNEIAREKPIAWYVQLLKTVTNPLSLLLIVLAVISLLTGSPTAALIIFIMVIFGGLLRFSQEFKSNKAAEKLREMVSATATVNRQDATKDAAPKEEKGITAGKEIAVKLLVLGDIIFLSAGNMIPADVRLIAAKDLFLSQSTLTGESLPAEKHVDLPANNKEKNPLELVNLCFMGTSVVSGSGTAVVAQTGSHTYLASLAKTVSGRKPRTSFDKGVNGVTMLLLRFMMIMAPLVFLINGIFKHNWVEAFTFGLSVAVGLAPEMLPVIVTANLAKGAITMSEKKVIVKNIDAIQDFGSMNILCTDKTGTLTQDKIVLQRHLDPYGQESLDVLKYAYLNSFYQTGLKNLLDVAVLDRNQELKSLDIEKNYQKFDEIPFDFVRRRMSVVVEEMGKQHVLICKGAVEEVLKICTQLQVNDQVLPMDESVHTKVADLQQKLNSEGLRVIAVAYKVMPPDQSHYAIGDESNLVLLGNIAFLDPPKESASQAIKALNRNGVEVKILTGDNEVITRKICKDVGLPVQQVLLGSDIEALSDDELAKVAATTTIFAKFSPTQKAKVIQVLRKAGNVVGYMGDGINDAAALREADVGISVDTAVDIAKESADIILLEKNLLVLESGVIEGRKTFANIIKYIRMGTSSNFGNMFSVLGASAILPFLPMQPVQILINNLLYDFSQTGIPFDRVDREYLVNPPKWKIDNIRRFMMFIGPISSIFDYCTYALMWFVFGANSVNNQALFQTGWFVESLMTQTLIVHVIRTAKIPFFQSRASLPMLLITATVMAIGMYLPFSPIAHSLGFVPLPAVYFVWLAAILTCYCVLTQFVKTWFIKKYGYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXR3</accession>
    <name>A0A2G4EXR3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-1-phosphate thymidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54240">
        <property type="protein sequence ID" value="PHX54240"/>
        <property type="gene ID" value="CP500_017190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04189">
        <property type="entry name" value="G1P_TT_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005908">
        <property type="entry name" value="G1P_thy_trans_l"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01208">
        <property type="entry name" value="rmlA_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="357" mass="38833" checksum="64CF99D79F656AE5" modified="2018-01-31" version="1">MKALILSGGKGTRLRPLTYTGAKQLVPVANKPILWYGIELIVAAGITDIGIVISPETGEEVKAKTGNGDRFGAQITYILQDKPAGLAHAVKISKPFLGDSPFVMYLGDNLIESQLHPFLDTFKSHQLDALIMLREVSNPSAFGVATVDEKGQVLQLVEKPKIPPSNLAMVGIYFFAPTIHEAIDQIQPSARGELEITDAIQQLINQQKKVEASNLEGWWLDTGKKDDLLSANQIILDSRLLASTELKVDAKSQIVGRVQIGEGSEIINSTVRGPVIIGKNCHIENCFIGPYSSIADRVTMIDADIEHSVILESAKISGIQQRIVDSVIGQRAQLTNAPIRPKALRFMIGDDSQIELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXR6</accession>
    <name>A0A2G4EXR6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54319">
        <property type="protein sequence ID" value="PHX54319"/>
        <property type="gene ID" value="CP500_016730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="146" mass="16897" checksum="49FCCB6134C11F6D" modified="2018-01-31" version="1">MRIKDSVWQGSFGYWQNLFIHQNILSIGYTAWNGFWHLGRGIVVCKIDTPINGSINWSVDNVQYDLQFISRSHATAYLQQLELEENTVSNLVQIIDSYEPEKAIIFIILANGQIDINLLQNLAISPVECYEQVCKRWEEFQLCPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXS3</accession>
    <name>A0A2G4EXS3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">glmS</name>
        <name evidence="11" type="ORF">CP500_016600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54335">
        <property type="protein sequence ID" value="PHX54335"/>
        <property type="gene ID" value="CP500_016600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="300"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="478"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="633" mass="69718" checksum="1C370BBA5A838034" modified="2018-01-31" version="1">MCGIVGYIGTQAASEILLAGLEKLEYRGYDSAGLATIWEGEITCIRAKGKLHNLREKLAETENPAPIGIGHTRWATHGKPEEYNAHPHMDNSGRVAVVQNGIIENYRELREELKAKGHKFVSDTDTEVIPHLIADFLAEENRNKQENLADLSFLEVVSKAVNRLEGAFAIAVICADFPDEIIVARQQAPLVIGFGAGEFFCASDTPALISHTRTVLSLENGELARLTPMGVEVYSFAGQRLKKSPRILGWSPVSVEKQGFKHFMHKEIYEQPAVVRACLETYLDNDWNPESTHSPINLELPKELCADVEQISILACGTSWHASLIGKYLLEQLANIPASVQYASEYRYAPAPMTANTLIIGVTQSGETADTLAALGMEQQRRAGFTDQYRARMLGITNRTESSIAHMIPNIIHTHAGIEIGVAATKTFVSQLMAFYFLALDLAHQRQTISNERLAEIIAGLRQLPAEIEKFLEIQEQYVEELSHQFTETQDFIFLGRGINFPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDAKVPVVAIAMPGSVYEKVLSNAQEAKARDARLIGVTPKQGAAEADIFDHILPVPLVDELLSPIVTVIPLQLLAYHIAARRGLDVDQPRNLAKSVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXW2</accession>
    <name>A0A2G4EXW2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000110">
        <property type="protein sequence ID" value="PHX54290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54290">
        <property type="protein sequence ID" value="PHX54290"/>
        <property type="gene ID" value="CP500_016920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="13391" checksum="BA8D4975294537AE" modified="2018-01-31" version="1">MDKLTEYPKLIDRILTEYIELCNRRPQPDIETFLITDAQNGHYMWINLGWQKGERITGITVYVRIRDGKFWIEEDWTEDGIATDLVRLGVPKEDIVLAFHEPGMRQYTDFAVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY45</accession>
    <name>A0A2G4EY45_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ORF">CP500_015980</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54454">
        <property type="protein sequence ID" value="PHX54454"/>
        <property type="gene ID" value="CP500_015980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="20"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="282" mass="31300" checksum="62D72AC6AC17852C" modified="2018-01-31" version="1">MRSPTPRKQFAQHWLKSEKALDKIVKAANLSGSRVLEIGPGTGILTRRLLAEAESVVAVEIDRDLCQRLAKQLGKADNFLLLQGDILEMDLDSQLVVFTKFQNPNKVVANIPYNITGPILQKLLGTISVPAAKPFDSIVLLVQKEVAERLYAKPGSRAFGALSVRVQYLAECELICDVPSKDFVPPPKVDSAVVRLLPRLIETPAVNPRHLESLVKLGFGSKRKMLRNNLKATVDLDKFVELLEELQINPESRAEDLSVEQWVNLSNHMISSQSIVDDAVHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYB3</accession>
    <name>A0A2G4EYB3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (cytosine-N(4)-specific)</fullName>
            <ecNumber evidence="3">2.1.1.113</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_015900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:16857"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:13674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:137933"/>
            <dbReference type="EC" id="2.1.1.113"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.113" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245731">
        <property type="entry name" value="M.Tbo703ORF15900P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54468">
        <property type="protein sequence ID" value="PHX54468"/>
        <property type="gene ID" value="CP500_015900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015667">
        <property type="term" value="F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017985">
        <property type="entry name" value="MeTrfase_CN4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00093">
        <property type="entry name" value="N4_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="425" mass="48153" checksum="0EB324725017864B" modified="2018-01-31" version="1">MQLSLFTDPIHPSLAPTNLTSSRHPIHRWANFIAGYSPEFVSECIREAYLSPGDTVLDPFGGLGTTPVQSLLDGFSCIACEANPYFAHIAIAKCQAALGNVDPDEVFSTLEQLVSYEGDLAEIYSVDALKFLHKLIPEAQLRVLVSAKMRELEIISENRLFYRLIVSMILELTSKSQTDGIYKAPTTKKKSSSFQEALLRVKSQVMEDFYSTAKKSNINYDFIKGTAHLLSEKPSSVASLCVTSPPYLNNFDYAEMSRMELYFWGYAESWREITNKVRSVLIPNTTTIPTEIKKNHELYARQLSSEFIQHLRPLVDELKIRRTQRAGKKDYYSLIYPYFAEIKKVFAECFRLLKSNTDIHVVIGDAYLYGVHIPTGQLTLSLLKEIGFDRMEIKLLRTRGSRWILSKREGAGTPIGEYLISGKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYF7</accession>
    <name>A0A2G4EYF7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mini-ribonuclease 3</fullName>
            <shortName evidence="2">Mini-3</shortName>
            <shortName evidence="2">Mini-RNase 3</shortName>
            <ecNumber evidence="2">3.1.26.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Mini-RNase III</fullName>
            <shortName evidence="2">Mini-III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mrnC</name>
        <name evidence="4" type="ORF">CP500_015510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MrnC RNase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.-" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54559">
        <property type="protein sequence ID" value="PHX54559"/>
        <property type="gene ID" value="CP500_015510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01468">
        <property type="entry name" value="RNase_Mini_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008226">
        <property type="entry name" value="Mini3_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005520">
        <property type="entry name" value="UCP005520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RNase III" evidence="3">
        <location>
            <begin position="19"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="16566" checksum="3D1E6DDEF3DA68CE" modified="2018-01-31" version="1">MSPIANNEQKLSLNDISLNRLHPGMATSAEIERLSPAAWAYLGDAVYELHVRTLYLVPPKRLQAYHELVVGQVRAETQARHLRSISPYLNSTELAIVKRGRNAAAGRSKRADPEIYQQASSLETLVGYLYLTDPERLNQLLALLELDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYH3</accession>
    <name>A0A2G4EYH3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000090">
        <property type="protein sequence ID" value="PHX54582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54582">
        <property type="protein sequence ID" value="PHX54582"/>
        <property type="gene ID" value="CP500_015330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="105"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="317"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="594"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="817" mass="84993" checksum="D82AA5D155163A3F" modified="2018-01-31" version="1">MKRIYPKKNQPVKASEIDRDGSKEQSKQTTLSTGRVRSLATIGLAISVGASGILLPRSGDSARASELAPIPEPTAEVQAASASELATSVGDAPSATPTAEPSNPVAVKVQPGQTLWELSQDYAVAPNSIATANGIESDTLLQVGQKLTIGPAEVVASSQQNADNTPVAAPPDYVAVVNPEQKLDLTGSEPSSSPVVQSGPPSTAANPLETLTPEQNSIVAPNTNGAIDSLKKQENRTAEFGQTQLGSELPTSLSTSTLSLQSPAPTQVSSTSATRTVIPNAGFDQANSSIEQSLVTPSLPSAVVVPSAGTTPVVTDVTYSVRPGDTLGAIASSQGVKVQDLISINKLGNPNFLNVNQRLKIPQVALNNPAVQAPASIQASNSTSSFSTASVPGSLNPSSSTPEIPGSGVTVSAPTVPIVSPLANLEGLNNISAPMVPQINNISLTQVSQNISDPRKLEIPGEPTFTGAVDTSALPMPATATASSTLTGAYPQPANWTPVVNTQGLATETANAVPESSAATQSTQELSPYAERLRAEVVRLREEYRAERNSIGPNSVALVPTADSETQVAAGNPSEDNEQLNPYLYTPEYRGTVQNEISRPPSRGWSEEVQKQQQERLDAARAAQSQPLNLTPASNLDRPVVATAPLGSQGYDPLSNPSLGQMVSPELPPLSGADTYLPKGSRQQSANGFIWPAKGVFTSGYGWRWGRMHKGIDVAGPIGTPIVAAADGVVTYAQWNDGGYGHLVEITHPDGTETVYAHNSRILVQKGQRVAQGEQISEMGSTGFSTGPHLHFEIHPAGSGAVNPMAFLPKDDSSASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYT2</accession>
    <name>A0A2G4EYT2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54646">
        <property type="protein sequence ID" value="PHX54646"/>
        <property type="gene ID" value="CP500_015080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="482"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="784" mass="83115" checksum="D73CDF6C95428474" modified="2018-01-31" version="1">MLTGGGDKVNASDVAVSSDGTVKLTNAAPKNSPPNNLVENNSAAVPISPQPTNVSQSPTNTVNQNSPPNNSNGGISAPPTNTVNQNSPPNNSNGGTSAPPTNTGNQQNSPPNNSNGGISGLPNNTGNQQNSPPNNSNEGTSAPPTNTGNQNSPSNNSNEGMSPEPNNTGNQNSPSNNSNGGNAQIPGNALPNNSASPTVFNANISAPNNSQPPMSPPGMADIIRVQGNRIQNSLLPNIQPNSPINGQIMPNNNFGLIPNNIQILSSPPILNSQPGNPNILQNSFLPNSQTNSLINGQIISKSQPGVSPNNNIQVLASPGTIVGNSPQPAASNPQQPGGGNTTEMRGRSGENLPPGVPNIPSGGANPGGNLAAISNMNYLLSVEQNRADRYSAYFGESLTNEPMAAENIRETLGKISSQTGKRSAIIYINLFSDRLELLLFTPDGSAIRKTVSEADRTTVLELAKEFRQEISNPRKRNTNSYKESARNLYDRLIAPLEADLQSQGINTLLFSLDTGLRSLPLAALYDGKQFLVEKYSLSQIPTISLTDTRYQSLQNASVLAMGAAQFTKLSPLPAVPIELANIADLWPGKSFLNEQFTLNNLKSQRSQRPYQIIHLATHGEFQPGTASDSFIQLWDSKLQLNQLRQLGWNNPPVELLVLSACRTALGDEETELGFAGLAFQAGVKSALASLWYVSDEGTLALMSEFYQQLKTAPIKAEALRQAQIAMLKGDVRIEQGVLRGLSAVSFAQGTRGGTPLPAELANMGDRNLAHPYYWAAFTMIGSPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ18</accession>
    <name>A0A2G4EZ18_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisH protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54762">
        <property type="protein sequence ID" value="PHX54762"/>
        <property type="gene ID" value="CP500_014360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="16019" checksum="18EB7140ADB1E2DA" modified="2018-01-31" version="1">MPAKDLYHDAVKQALIKEGWTITADPYTVEYEEFKVFVDLAADRSLAAERGSQKIAVEIKTFLRPSFVRELENALGQYILYRNLLSVTDPERELYLAVSDRIYNNFFQKKASQFIVNQNQISILVVEIQSEVISQWIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ50</accession>
    <name>A0A2G4EZ50_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54781">
        <property type="protein sequence ID" value="PHX54781"/>
        <property type="gene ID" value="CP500_014260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="98"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="776" mass="88578" checksum="6767C76DDC790AE7" modified="2018-01-31" version="1">MGKLVVLTFAEGDLDKAGFPVTLQLGDEGKPATIQEIGSLPPNPELVESYTSWKVTYYGFIGVKVRKLEAKVAQTTNFSIGDVNAKAENLSQNFNQWLKSQQFSHVREELVAHLKENDEVRLIIQTSNIQLRQLPWHLWDILKRYPKAEISVSAPIFRQVTSAKVANNQVNILAILGDDEGINVEEDRKILNSIPGAKVEFLVKPNRQALNDQLWEQSWDILFFAGHSRTEGETGIIYINQTESLTIPDLRYALKKAIEKGLQLAIFNSCDGLGLAQDLADLNLPQMIIMREPVPDKVAQEFLKYFLRSFSGGQSFYLAVKEARERLQGWESQFPCASWLPLICQSRAEVVLTWNDLRDRTRNLINVVAKAVQLGVARLLPLPLPLPLPLPLPLPFYIRRGLLISRNNKSKSSDVTLIDASLDPHDSPYEQSIERGRKIIRHQQKENLEEDSLFSIEIENVDENYFYSFPTIDCKFQNTGNATAFLWQFAVNVIQAKIDFTPIPDFSYCVKNGALEVEIINNGWGSMRDCEIQIDEPIINRLFSESVRQYRGTIDSGKSQTFFRLSKEMAETKNFEAISKEFKTIGIESPGFSPFDESPEKFLVDRRLTYGIKLNTLRIKLSFKDEKNTISTGEKEILINDIALTPTGFYDLKCFMGFDHDYDGECNSYVTNAIIIDPKKGSHERIYPISRKIPPGDVERFHIMVCATMSCHLRLQFEFFVDRDQIVKSEVFDINIWNPVNAEWHKKYQDGVHLNRDGHIEFFGIDIDMNEILGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ69</accession>
    <name>A0A2G4EZ69_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54811">
        <property type="protein sequence ID" value="PHX54811"/>
        <property type="gene ID" value="CP500_014185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="136" mass="15195" checksum="AA3E9E592F33073C" modified="2018-01-31" version="1">MTFIPSEAFKSISYPDRTVKRADRAIRCSPFQLHFFQTIRDNSVFLTTIASNSGVERGYTRSPVAELAAENSLLWLIQVGVLRREVDGQGITDSFRLTPLGRQLVEKWEGEGDKVPDASLCDRLGNAFSRGLGLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZB5</accession>
    <name>A0A2G4EZB5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_013795</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SecG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54850">
        <property type="protein sequence ID" value="PHX54850"/>
        <property type="gene ID" value="CP500_013795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="8309" checksum="ED955C2C8CBADDCB" modified="2018-01-31" version="1">MNIVSLLQIIWSVSAFGVVVLVLLHSPKGDGIGGIGGQAQLFTSTKSAETTLNRITWGLAIVFMGLTVILSAGWLTPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZF0</accession>
    <name>A0A2G4EZF0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54890">
        <property type="protein sequence ID" value="PHX54890"/>
        <property type="gene ID" value="CP500_013725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="554" mass="62200" checksum="BC6F12416DB8C814" modified="2018-01-31" version="1">MFKTKRKSPKSKHKRKENNTALSKKEVSTQKRKISQKRNQLVQAIAINTLISAGVTIPLLFVTRAKLAIAAGTAVAILLFSYKYPRQALWAFLIYLPFSGTITYAIGGGNAAFQVAKDAFYIPALIALIQSCKNKQLPIFLPKQLMPTFSILLMMALLTLIFVNGDMQLNPMKGEKPLLQGILGLKVLIGYIPLITCTYYLIRTKKDLIFFSRMHVILAIVCCILGLIQYLLLQSGRCAGTRGMSGAELYKATLQARCFVGGSLVFSPEVKFIRLPGTFVAPWQWAWFLIGNAFLTFASAFCDPSFWWRTIGLFGMALVFANAVISGQRTALVMVPVATFVLLILTGQLVNFKRFIPIGAGLAILLFVGAAINPGIIEQRWESFVNRWNAAPPQQFLFNQFEQSHNFIIDRHLGRGVGRATNSTRTFGATQLIETFQPKLMYELGYPGMIAFQLMVLHLAFLTFRAYRSVKDRSLRTYGASFWVFVAFITVNTQYYPLDVDPVSVYYWVLAGAILKLPKIDKQVQDEKHEEVNVDELEVRQQLKEKKIIASAPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZL3</accession>
    <name>A0A2G4EZL3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molecular chaperone DnaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_013450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54954">
        <property type="protein sequence ID" value="PHX54954"/>
        <property type="gene ID" value="CP500_013450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="529" mass="58924" checksum="22F65B5C1E0A9884" modified="2018-01-31" version="1">MAIAIDFGTSNTVVARTNPATSQPETLKLPALSAISAQNPPLIPSLLYVENAAQNQVILGQQVRDKGLDLTTDSRFFRNFKRGIGTPIQGFVPELDGQIVTFEQVGQWFLSQIVGSIRELSVPVDSLVFTVPVDSFEAYRNWLGKVSQSLQVEQVRMLDEPTAAALGYGLADRENLLVIDFGGGTLDLSLVRLDISANKKPLGFLLKWGDRSLAESSGQKAKIARVLAKAGQNLGGSDIDNWLADDFVKNTGMMKSSIITRLSERLKIQLSLQERATEVYFDEENFETYELELNRDRFEAILAEHQFFDNLDESMNQVLQQARRQGLEIGDIDAVLLVGGTVQIPAVKRWVEQYFDTAKIRCDKPFEAIAQGALQLSQGVEIKDFLYHSYGIRYWNRRENCHSWHNLIKSGQSYPMTEPVELVLGASLENQPSIELIIGELGAETGSTEIYFDGDRLITRQLAGQTSVQPLNDKDGARSIAQLTPPGYPGGDRIKALFRVDEQRFLRITVEDLLTNQTLLEDKPVVQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZT7</accession>
    <name>A0A2G4EZT7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55023">
        <property type="protein sequence ID" value="PHX55023"/>
        <property type="gene ID" value="CP500_012980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="13400" checksum="E1B63AEEE5861AA6" modified="2018-01-31" version="1">MSQSDNPKEILQANSVNLSALTEKLVTTGALNFTSTEEVEFDLKNRDKDKQFEREQKWISFWVKDIGVFLAALLLVLLIDVYALTILVSETASEGKIRFAIAALTSSVTSLLSYLVGRSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZY0</accession>
    <name>A0A2G4EZY0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_012715</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2Fe2S plant-type ferredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55079">
        <property type="protein sequence ID" value="PHX55079"/>
        <property type="gene ID" value="CP500_012715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010241">
        <property type="entry name" value="Fd_pln"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02008">
        <property type="entry name" value="fdx_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="6">
        <location>
            <begin position="4"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="11797" checksum="43E9FD3263B85A13" modified="2018-01-31" version="1">MAVYQVRLVNQEIGLDRTIAVPDDQYILDMAEAAGIRLPNGCKQGECSACLVKLLNGEIDQSEQKFLKPSELEAGYAITCVAYPLSDCTLLTHQEQVLYQKSLYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZZ7</accession>
    <name>A0A2G4EZZ7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_012660</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55068">
        <property type="protein sequence ID" value="PHX55068"/>
        <property type="gene ID" value="CP500_012660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="13">
        <location>
            <begin position="3"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="11">
        <location>
            <begin position="165"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="12">
        <location>
            <begin position="290"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX55068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="363" mass="41264" checksum="C2582C315EDD018D" modified="2018-01-31" version="1">MFAVKRALKLNNNEATLMARHAGFRRVVFNFGLSLRTQMYSEGKFTDSKVINEVKKVLTNYVKKKPEFDWMNQLSSRVYQNALIDLKDAFSRYRSGSSGHPKFASRRDGQSFTVDSSNGKVLLNVGKTIKIPTLGTFRLFEPLECSFISQTFTISKEGNRWFVSFCVDAERLPVQLAEDSVGIDVGIKSFATLSKGQVFDAPKPLKQAKTKLATLQRQASKQVKGSRNQRKTYNKIRQLHARIAHIRLDFLHKLTTYLAKTFKLIKIENLNVKGMMANHKLAGAISDLGFYEFKRQLDYKCRMYGSRLVLVDQWFPSTKTCSNCSSKKDMPLSVRTFDCPACGISLDRDFNASVNILNWEPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F016</accession>
    <name>A0A2G4F016_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase_S8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_012500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55088">
        <property type="protein sequence ID" value="PHX55088"/>
        <property type="gene ID" value="CP500_012500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="55"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="362" mass="39192" checksum="57CBFB6ADDFAB947" modified="2018-01-31" version="1">MTDTSKLLKDLEKEPLFKDQWWLFNEGQTDIGGKKIKSNRGIDLNVVPLWPFYTGKGVKVQVIDDGIDSGHEDLKDNFKEVSEKDIEKMLPGFDGSHGTAATGIIAARRNDLGTVGIAYDATFGGYKFNTNSLNSLQAQDQFDVSNNSWGLVYNFVNVNTNVAAIENAVTNGRNKLGTVSVWAAANSREQINPNLAGVEQRGNNANLSNYPNSRYTIAVAAINNEGVVASYSNPGAPLLVSAFGDEAPSIATVDRTANSGYNPQSSPNFPSLNYTNDFNGTSSAAPMVSGVAALILQANPKLGYRDVQEILAYSARKNDPNNQVVKSYSYESQKIPKDTWAFNGAKNWNGGGLHVKRLLANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F021</accession>
    <name>A0A2G4F021_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_012630</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55114">
        <property type="protein sequence ID" value="PHX55114"/>
        <property type="gene ID" value="CP500_012630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033463">
        <property type="entry name" value="sCache_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17202">
        <property type="entry name" value="sCache_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="12">
        <location>
            <begin position="396"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="505"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="758" mass="84385" checksum="D2D17FEC90485954" modified="2018-01-31" version="1">MLIAKLWSNYSFRTKLSILIVSCVVLPTILVIHNILNLAEKHLVQRMQDTLQQSLGILEWQVKQVEQFHAHIAISLAEIVGNTNIDLNDPVAVDQQSDILQEIINNPIKISFECSFYILTDAQGKTIAQNIQILKDDFDRYPQLPSQEEAPPSLVYRAVAQPKKIEMGTLPIVNYALQQGKILSGLELLNYDLLQHLGIDRQADIGERFQKIQGLPINKQPVSAGIYNINKGKIGLGIIVVYPIKREGKVIGSTIVGTLLNRNYQIVDTVRKISGATTVTIFAKDWRVSTNVPYPDEKTRAIGTRAASEVAEAVLDREQIFLGNTNIAGQNYMTAYAPIYNYEHQLNIPTKPIGMYSVADSEVQVREVLMKLALTGYTVGISILILAVGVGLIAAKTFSYPLRRLTEFAQQVAQGKQGVRLKLSNRRDEIGILTRELNQMATSIEQNLIKLVASEAAIKEAEINRRHLAQEKATQLEATLQKLYSTQSQLIQTEKMSSLGHLVAGISHEINNPVNFIHGNLNHASESVISLIELIDLYRKLYPQPRPEIESKVEEIDLEFMIKDLPKMLDSMQMGSQRIRKIVSSLRNFSRHDEAEIKPVDIHSGIDSTLLILQHLLKANGEDPEIQVIKQYGELPLVKCYASAINQVFMNIISNGIDALRDAQKNCADWNKEPIIIIRTLVNDDRNLVVSIADNGLGMEQSVIDKIFDPFFTTKLVGKGTGLGLSISYAIVVEKHGGKLSCVSAIGEGTKFAIEIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0H1</accession>
    <name>A0A2G4F0H1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55238">
        <property type="protein sequence ID" value="PHX55238"/>
        <property type="gene ID" value="CP500_011915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="17596" checksum="9D354BB7EAB74EE1" modified="2018-01-31" version="1">MCGHSDELWHQVINVNLNGVYRTIKLCLPEMIDRQWGRIINIASTAASVGSPTNAAYCASKAAVVGLTRCVALEGAPHGVTCNSISPGWVETNFAKNWMRQLAETEDKGLAEYMEEIKQTNPQKRMIQPEEIGELAVFLCRDEALGITMQDITVSAGSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0P8</accession>
    <name>A0A2G4F0P8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55325">
        <property type="protein sequence ID" value="PHX55325"/>
        <property type="gene ID" value="CP500_011300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="296" mass="32453" checksum="6D97F484D7000F62" modified="2018-01-31" version="1">MNKPIDLSSNSIKIKLLNYLAQELLTPLTSVIGMASVLSQEIYGPLTSKQKEYIDVIQDSSRSLRSLVEEILGLADIDDSTFTIKRTAVDIESLCQQVVTTLSQPASKREQEINLSMSPGPRIWLADKEKIQQMLHHLIFSVIQSAGAGSVIRVHVFRKDEGINIGVWVFHPWLGESLPHAKLYSDYLLKVESASNSASNSDSRELGLEPQLPQAVQGSQRFQLSFSELAALVAVNSADSAPLLAGYGERERLGLLLCCQLVEIQGGKLSIQGSPESGYRYVLSLPCVNATELLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F103</accession>
    <name>A0A2G4F103_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55439">
        <property type="protein sequence ID" value="PHX55439"/>
        <property type="gene ID" value="CP500_010885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="145" mass="16491" checksum="70FE95B6AF4480D3" modified="2018-01-31" version="1">MAGVCRLSITETIEELKSLLTEQKTVSGFQKIQALYLFKNCQIKTVKELALTIGVNRITVQRWLRKYRSDGLEGLLETKHSGGRKPAIPPLARASLAVRLSDPQKGFRSYGEIQEWLQQEYNIEASYKAVYATVRYQLKGKLTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F135</accession>
    <name>A0A2G4F135_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55469">
        <property type="protein sequence ID" value="PHX55469"/>
        <property type="gene ID" value="CP500_010605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02522">
        <property type="entry name" value="GT_2_like_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026461">
        <property type="entry name" value="Trfase_2_rSAM/seldom_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04283">
        <property type="entry name" value="glyco_like_mftF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="237" mass="25919" checksum="712BD84DEFD129B2" modified="2018-01-31" version="1">MPEIPNLKISIIIPVLNEASTIAPVISTARNAENVEIIVADGGSSDGTVEIAKSLSDRVISTTPGRATQMNAGAAASTGDILLFLHADTYLPDGYDTGVRQALGNSSIVAGAFELKIDAALLSLRLVEIGVRCRSHLLQMPYGDQAIFLKTVTFEQMGGFPKLPLMEDFEFVRRLKKQGRIEILSMPVLTSARRWQQVGVLKTTVINQIVIIAYFLGVSPDRLGEWYRGKRKNYSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F145</accession>
    <name>A0A2G4F145_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55473">
        <property type="protein sequence ID" value="PHX55473"/>
        <property type="gene ID" value="CP500_010640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="83" mass="9342" checksum="1DF6EAE2F1D26393" modified="2018-01-31" version="1">MKWREQINFDTKVPAKPAVPETRLSVEFLLGLFAAGWTEQQVLEKYPALTLEKLRAALATADSGLLSSIANPELLEMIQRTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F190</accession>
    <name>A0A2G4F190_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-amylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55515">
        <property type="protein sequence ID" value="PHX55515"/>
        <property type="gene ID" value="CP500_010435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="16"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="494" mass="56598" checksum="46FA939CCCDFCA3D" modified="2018-01-31" version="1">MQIQTPDWVKHAVFYQIFPDRFAKSKQPRKRLLQNFMWEEWHEIPTLQGYKGGDLWGVMEQLDYLQDLGINAIYFTPIFQSACNHRYHTHDYYQVDPMLGGNLAFKELLDAAHDRNIKIVLDGVFNHASRGFFFFHDILENGPNSPWLDWFKIEGWPLSAYDGNLPANYAGWDGNRALPVFNHDNPEVREYIMEIAEYWIKFGIDGWRLDVPFEIKTPGFWQEFRERVKAINPEAYIVGEVWHDAREWLDGTQFDGVMNYLFAAETIAFAAGDRVDKSQLEGRSYYPYPPLFAKEYGENIQELLALYPWPIQLTQLNLLASHDTARLLSIAGGDKKSVELATLLLLTYPGAPSIYYGDEVGLPGALDPDSRRGFPLEAHWEIDVFDYHKQLIGLRQKYCALRTGGYEILFAEGTVYVFARILGDEEIVVAVNVGTESANISFEVPVTERSRSVKSPHGKLLFGKGKFVWKGEGETRHLELMLPARSGLIIGPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1A0</accession>
    <name>A0A2G4F1A0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidylprolyl isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55526">
        <property type="protein sequence ID" value="PHX55526"/>
        <property type="gene ID" value="CP500_010500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="2">
        <location>
            <begin position="126"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="251" mass="29129" checksum="501B15B87DB789DD" modified="2018-01-31" version="1">MKNFYQPLIQADEIIDSLKQELQVKPFYQRILQKRVIDKAAKERGLTVTPDEIQAEGDKLRREKRLERAADTIAWLAEQMISVEDLEAGICDRLLAQKLAECLFAKDVNKIFVQNKLQFDGIILYQIIVQEPELAQELFYQIQEGEISFFDAAHFYDIDENRRNLCGCEGKVYRWGLKPDIAVAVFSAKPGAVIRPIQTDLVYHLFMVEKFLPAELTAERHEEILQKMFDEWLSNEVNYLLYNQPEIALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1G1</accession>
    <name>A0A2G4F1G1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55589">
        <property type="protein sequence ID" value="PHX55589"/>
        <property type="gene ID" value="CP500_009945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="181" mass="20275" checksum="9FE00A7E6D948097" modified="2018-01-31" version="1">MTTLTVEILCSEAAIFSAAESQHPEPLLYGITDGKAVGTYLEQKFRLYLKQRYEFLDGNSASGIDFPGILVDMKVTSVRQPQSSCPFKSARQKIFGLGYSLIIFVYEKTDNSTIRTATLNILHTIYVSAERTADFQMTRGIRNILDNEGNKDDLLAFMFDKNLPNLGKLRSAGFIKNWSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1I3</accession>
    <name>A0A2G4F1I3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrate ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55634">
        <property type="protein sequence ID" value="PHX55634"/>
        <property type="gene ID" value="CP500_009770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMT1" evidence="1">
        <location>
            <begin position="32"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="313" mass="33889" checksum="5F45AC8653C06BFB" modified="2018-01-31" version="1">MVAVTLCTAILASCTKAEPPLRVGANVWPGYETLYLARSLGYYNNTPIRLVDYPSGTEEVRAYRNGEIEAAGISIDQALVLAATNPDVRIVVVMDFSNGGDVILGKPEIQNVQGLKNRPVGVESSALGAFIITRALEQKGMSPQDIKIVSLGVSEHERAFKQGTVDAVVTFGSARTKLLAAGAKLLFESSQIPGEIVDVLIVRNEVIEKQPKALQALVDGRFRALDYLTKNPQDAAIKIAPRTGVTPEQFLESLKGLRSPDLPENQKLLAKTDPSLLNGVKRLSQVMLDNKLLPKAVDTAPLLDDRLVRNVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1V0</accession>
    <name>A0A2G4F1V0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55715">
        <property type="protein sequence ID" value="PHX55715"/>
        <property type="gene ID" value="CP500_009480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="10"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="165"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="33871" checksum="36429EE20E0B8CC0" modified="2018-01-31" version="1">MNQSNKTTMAIASLLVGVVAISFGSIFIRWSEAELSPNATIFDRFWLGSVVFGLWQGYKAIRQRLSGDKPVEQHSYTSQELLLLLGAGIFFAATLSFVAWSLTQTSIAISTILHNLAPIFTSLGAWLLFGQGFNRQFLIGMVVAIGGAITIEIEQIQIATGEVTGGIAAILSAVFLGAYLLVIEQLRTKFDPITIQLWVCAIATFSILPILVFTGDRLFPSSVNGWLFVIFLALVCQVLGQGLLTYSVAQLSSVVVSLVHLLEPVFSSILAWAIFGEKLSFSNGVGFVLVLIGVYLAVSSQAAVDIQQNQLESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1W4</accession>
    <name>A0A2G4F1W4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NCS2 family permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_009110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55754">
        <property type="protein sequence ID" value="PHX55754"/>
        <property type="gene ID" value="CP500_009110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904823">
        <property type="term" value="P:purine nucleobase transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026033">
        <property type="entry name" value="Azg-like_bact_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="PTHR43337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005353">
        <property type="entry name" value="PbuG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="478" mass="50829" checksum="263DE52403324DF0" modified="2018-01-31" version="1">MSADLEFQKPIPPKQSYTGWQAALAEFFQFDFYRTNFRTETIAGITTFMTMGYILVVNPIILSNAIFLQQPGDLFSQLAVATAVASAVGTFCMAILANYPFGLAPGMGTNAFFAFSVVIGLKIDWRLALSCVFVQGLIFMLLTLTDVRKLLIAAIPKSLKHATAGGIGLFIAYIGMSGDVVNGGAGLIVANPATKTAFGSLAEPNTLLAVAGLAMTAGLVVRGVRGALLFGIFGTAIWAWLFKVSPPPQGFFALPELPKDIFGQAFLGIANLNAENFIDWIAVLFVFLFVDIFDTIGTLTGVGMRAGYIGPDGELPRANKALMADAIGNTIGPIFGTSSVTTYVESVAGVAEGGRTGFTALVVAGLFTASLFFIPVFKAIPAFATTPTLVIVGAMMLAEVKEIPWDDMSEVIPAFLTIFLTPLTYSIAEGLSIGFIAYPIMKTCQGRAKEVSGGTWIVAGIFVIRFIFMSLRFHHSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Y4</accession>
    <name>A0A2G4F1Y4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_009155</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55759">
        <property type="protein sequence ID" value="PHX55759"/>
        <property type="gene ID" value="CP500_009155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018632">
        <property type="entry name" value="AAA-associated_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09821">
        <property type="entry name" value="AAA_assoc_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="11"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="447" mass="49694" checksum="3B5966B5E1652EF3" modified="2018-01-31" version="1">MVAKIATESLITLEGVSKVYQQPNGQKISILEPIDLELRSGEIVALLGPSGSGKSTLMRMIAGLIPPSDGQVIYHNRPLVGLNPGVAIVFQNFALYPWLTVLENVELGLKAKGELPEPRRQKALRMIDIIGLDGFENAYPKELSGGMRQRVGFARALAVEPELLCMDEPFSALDVLTAENLRFELLDLWLEKKIPTKAVLIVTHGIEEAVILADRIVVLGRNPGRIRAEITVTLPHYRDRKTTEFQAIVDQVYKILTNPELSCEIVTAPAASAAAVSQPQPAQSAKYQSLPQVRIGAVAGLLELLEDRKEKDLYRLGQELMLEVDDILPIVEAAKLMDFLAIQEGDLFLTTVGNQFIAGGIDERKQVVRTQILGNIRLVQQISRMLQSKRNHRISEELILDILEAHFSPQEAMRQLKTAIDWGRYAELYSYDEPGGEMFLESEDKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F219</accession>
    <name>A0A2G4F219_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArsR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55788">
        <property type="protein sequence ID" value="PHX55788"/>
        <property type="gene ID" value="CP500_008855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="14"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="13595" checksum="D4D99899D4FFFB38" modified="2018-01-31" version="1">MLKTSRIAPDLVAQSPISAKQIAAGFHALSDPLRIQILELLREQELCVCDLCDRLEVSQSKLSFHLKTLKEAALVRSRQEGRWIYYSLNLAQFLALEQYLSDYRRFSQILPARPCSDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F230</accession>
    <name>A0A2G4F230_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55833">
        <property type="protein sequence ID" value="PHX55833"/>
        <property type="gene ID" value="CP500_008755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="29"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="17522" checksum="1C8C1C98DC976D1C" modified="2018-01-31" version="1">MIEFKGSEKLPMFKKADLQVNTGLNGLDQVLSWFSQLYDSRIPISVWIRCQLALAEGFTNAVRHAHNGKPADLPVDIQVAVFAEFVEIKIWDWGDRFDLEAKIKTISEKVDLAAPGGRGLKLMKDIGDSLSYVRTADGRNCLSIVKNYSPCIHDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F233</accession>
    <name>A0A2G4F233_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Urea ABC transporter ATP-binding protein UrtD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">urtD</name>
        <name evidence="5" type="ORF">CP500_008935</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55802">
        <property type="protein sequence ID" value="PHX55802"/>
        <property type="gene ID" value="CP500_008935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017781">
        <property type="entry name" value="ABC_transptr_urea_ATP-bd_UrtD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03411">
        <property type="entry name" value="urea_trans_UrtD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="248" mass="27030" checksum="05E12478091142DF" modified="2018-01-31" version="1">MNGKVLEIENLTVSFDGFKAINGLTFSMDAGELRVVIGPNGAGKTTFLDAITGKVQPTEGRVLFKGRNLRGLSEDRISRLGIGRKFQTPRVFLNLTPRENLELSCNQNKNVFPTLFKPAPVAEKRTVAGLLETIGLVAKADVSAGLLSHGEKQWLEIGMLVAQSPDLLLVDEPVAGLTDEETVLTGDLLISLAQSHSVLVIEHDMEFVRQIAQKVTVLHQGAVLCEGTMDEVQNDDRVIEVYLGKPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F282</accession>
    <name>A0A2G4F282_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bleomycin hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_008440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cellular thylakoid membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55852">
        <property type="protein sequence ID" value="PHX55852"/>
        <property type="gene ID" value="CP500_008440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000081">
        <property type="entry name" value="Phycocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3 4" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="2 4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="184" mass="19327" checksum="6F9C7E967B366722" modified="2018-01-31" version="1">MLDAFSRAVVSADASTSTVGDIAALRAFVASGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIQDNPSEKFAGAKLRKMGTIVVEDRCATLVAEASSYFDRIISALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2H5</accession>
    <name>A0A2G4F2H5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_007985</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55974">
        <property type="protein sequence ID" value="PHX55974"/>
        <property type="gene ID" value="CP500_007985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="348" mass="37787" checksum="68F1ACE40B9B4D74" modified="2018-01-31" version="1">MLEFDRLFDTIAELVMLHSPSGVESEINQRLMEKFAALGVNAWLDRADNAIALIPGRNPQKSIAITAHKDEIGAIVKTVGSLGRVEVRRLGGAFPWVYGEGVVDLLGDKQTISGILSFGSRHVSHESPQKAQQESTPLTWENAWIETKCSAQELADAGIRPGTRMVVGKHRKQPIRLKDWIASYTLDNKASVAILLALAEYLKEPAVNVYLVASAKEEVGAIGALYFSQRQPLEALIALEICPIAPEYPIEDGENPVLLVQDGYGIYDEGLNRELRAAADRAGVEVQLAAISGFGSDASIAIKFGHVARAACLSFPTQNTHGFEIAHLGAIDNCARILKAYCDELSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2N3</accession>
    <name>A0A2G4F2N3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen synthase</fullName>
            <ecNumber evidence="7">2.4.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Starch [bacterial glycogen] synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glgA</name>
        <name evidence="11" type="ORF">CP500_007585</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Synthesizes alpha-1,4-glucan chains using ADP-glucose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56009">
        <property type="protein sequence ID" value="PHX56009"/>
        <property type="gene ID" value="CP500_007585"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033201">
        <property type="term" value="F:alpha-1,4-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:starch synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_5" evidence="10">
        <location>
            <begin position="2"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="9">
        <location>
            <begin position="267"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ADP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="480" mass="55028" checksum="AE46E7B5443F9E89" modified="2018-01-31" version="1">MRILFVSAEAAPLAKVGGMGDVVGALPKFLRRMGHDVRIFIPYYGFIPDKMDVPKKPVYEGAAMFETFSIFETVLPGTDVPLYLMQHPSFLPRRVYGGLDEDWRFTFFANAAAEFSWNHWKPQIIHCHDWHTGMIPVWMKQDPDISTVFTIHNLAYQGPWRWRLEQMTWCPWYMQGHNTMAAAVQFADRVNTVSPTYAQQIKTAAYGEQLEGLLSFLGDKVSGILNGIDTESYNPETDKYITQNFTADTLEKRPANKIALQEEVGLEVNKGAFLMGMVTRLVEQKGLDLIIQILDLFMAYTDAQFIVLGTGDRYYETQLWQMTARYPGRMSTQLLYNEALSRRVYAGCDTFLMPSRFEPCGISQMIALRYGCVPMVRRTGGLVDTVSHNDPINNTGTGYCFDRYEPLDLFTCMIRTWEGFRYKDKWKELQQRGMREDFSWDISAKKYVQLYSDVLGIPVEESAPEESAPEEPLELIVDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2P7</accession>
    <name>A0A2G4F2P7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_007665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56022">
        <property type="protein sequence ID" value="PHX56022"/>
        <property type="gene ID" value="CP500_007665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="102"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="260"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="306"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="360"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="432"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="64"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="536" mass="61181" checksum="B470F03821E46D1B" modified="2018-01-31" version="1">MLETIFQHLQALKSQGSQLSPAQQGILTKTLENLSNSLEELAASRQFESATNNTAKLIELEKSNRIFERTVAQQASQLKQLQEQLDKELSQYRRDNQALIKSEAKLQKVLRNSPNIISLLEPDGRVRYHSAAVTRVLGYKPETRIGKVHGELIHPDDLLNWKAYFGRLLEHPGIAKPIKYRVRHADGSWVYLEAVGNSLLRDSSVQGIVISSWEIGERNQAELAIKESEFRYKIMSQITSDFAYSFRVTPDRKFVCEWATEAFARCTGYLPEELAASGWWSSDLVHPDDKQMLIEQLQEFADLRMGTNEYRIVNKKGEVRWVKDRWQAVWDKTEGRIVRLRGACQEISDRKQVELQLELANQVLQAQIQSSPLAINCTDSEGKVTIWNHASEKLFGWSAIEVLGQDPPHIPEGQKQDFEDILESLFNGKAQRGFEVSLLKKNGGWIDLCLFAAPVQDSSGNTIGTIKIFSDLSERKRIEEERKKLAGLQNMEEPFWVRYITPPKNSKKNTKKQLNINNETQMISLTAEKPDDSIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Q0</accession>
    <name>A0A2G4F2Q0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD(P)(+) transhydrogenase (Re/Si-specific) subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_007530</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56041">
        <property type="protein sequence ID" value="PHX56041"/>
        <property type="gene ID" value="CP500_007530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008143">
        <property type="entry name" value="Ala_DH/PNT_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00837">
        <property type="entry name" value="ALADH_PNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="4">
        <location>
            <begin position="4"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="3">
        <location>
            <begin position="148"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="382" mass="40337" checksum="710203694018FB3E" modified="2018-01-31" version="1">MKLAIAKEIEAGERRVALVPDAVAKLVKQGVEVWVEAGAGAKSFFSDLAYEAAGAKVVADTATLWGEADVVVKIGELQESEVHQLREGGVFIGFLNPLGNPALVQRLADRHVTAFSMEMIPRTSRAQSMDALSSQANVAGYKAVLIAAAALPKYFPMLTTAAGTIRPAKVLVMGVGVAGLQAIATARRLGAVVEAFDIRPETKEQVQSLGAKFIDVELKEETVAAGGYAKELSEAAKEHTRQVLTQHVGASDAVITTAQVPGRKAPILVTREMVSQMKPGAVIVDLAAEQGGNCECTEAGKDVEWNGVNVIGPINLPGSMPVHASETYSKNVSSLLQLMLKDKELNLNFEDDIIAGSCVARDGEISNQRVRDALAAQASVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2S6</accession>
    <name>A0A2G4F2S6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56056">
        <property type="protein sequence ID" value="PHX56056"/>
        <property type="gene ID" value="CP500_007435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="146" mass="15951" checksum="184ACE1287EBF5DB" modified="2018-01-31" version="1">MKKVLVIEDNDLIRETVLEVLEWHGLEAVGAQNGLVGIKMAIAQIPDLILSDVMMPKFNGFEVFAALRSHYATASIPFIFMTGTEMEKALELKADGYLNKPCSVTEMLGAIANQLQKPKVIAQGRKKKANAVKSMVSAINNVLIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2V6</accession>
    <name>A0A2G4F2V6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3 5">4.6.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">moaC</name>
        <name evidence="7" type="ORF">CP500_007160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoaC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3 5"/>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56079">
        <property type="protein sequence ID" value="PHX56079"/>
        <property type="gene ID" value="CP500_007160"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaC" evidence="6">
        <location>
            <begin position="28"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="126"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="18134" checksum="DEF742CCD2EDC05B" modified="2018-01-31" version="1">MQDISQTFSELPDRALLTHLNNSGEAQMVDVSAKVATVRQAVAAARVRMSPETFVAIEAGNAPKGDVLGTARLAGIMAAKQTANLIPLCHPLPLSSVEVQVIADAELPGYEIRATVKIKAETGVEMEALTAVSVAALTLYDMAKGLSKSIAIESIRLVSKTGGKSGDYQNVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Y0</accession>
    <name>A0A2G4F2Y0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56106">
        <property type="protein sequence ID" value="PHX56106"/>
        <property type="gene ID" value="CP500_007310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="241" mass="27554" checksum="E5E736141DEA05AF" modified="2018-01-31" version="1">MLDTNYFDPRDIPIYSIPQAAQYLRLRKDRLRDWVGGWFSKTKAEKRFFEPLIKLPHPKNFELLPQSKTTLLSFTNLVEAHVLIAIFKATGFSRKQLSTELDYINDHLSTPQLYGGIEFQIEGIALLFERFGQKLAASDREQEARQILKTYFDRIVRDEAGLPLKLYPFTKLPGADEPKTVMIDPRISFGRPVLAGTGIPTAMLAERYKAGDSIDELAEDYNCDRLQIEEGIRCELPLLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F326</accession>
    <name>A0A2G4F326_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56173">
        <property type="protein sequence ID" value="PHX56173"/>
        <property type="gene ID" value="CP500_006940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13599">
        <property type="entry name" value="Pentapeptide_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="330" mass="35478" checksum="977F9AA6BC714B94" modified="2018-01-31" version="1">MNAGELLRRYTLGELDFQGMNLRGIYLNGADLIGVNLSNADLSGANLAMAYLNRSNLQRANLTNVKFGGANLNQANLSSANLSDADFHGATLQNADFRRANISLAVLIDANLTDADMRGVNLQGADLRGACLRGANLRQERMFNGANLRGANLQGADMRGVNLQGADLTKANLSRANLTEASLREANLSQANLSEAILDGVFLIEANLTETNFSWAVMTNAKLERAVLIDAEFAGTNLCGAFLPDVKLSNANLVMADLSRAKLMRADLSRANFNQANLSEADLTDAYLAKTDFRDAILHRTSLMRVDLSTANLVGAKFGGTIMPNGEIHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F337</accession>
    <name>A0A2G4F337_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56183">
        <property type="protein sequence ID" value="PHX56183"/>
        <property type="gene ID" value="CP500_006655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025478">
        <property type="entry name" value="COP23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14218">
        <property type="entry name" value="COP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="192" mass="21045" checksum="E8D851ADBAE880C9" modified="2018-01-31" version="1">MTIGILSLVAAVVGAGIAFVQGWPPVLFGKKDHFFCELRPDTQRGGEVWTVMYRHDKGVQPWLKMVTTLGGGYTPIRRCEIISERLETYRKDGLTQLGYRGDSNTPDQYVICAKTKLSGDNCPLLVTLKPGTQRSAYQSLQDITEDLRNGTGVYQGSEGKVANSNFSPSSPVIDLTPFLAEEDRIAGSNSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F363</accession>
    <name>A0A2G4F363_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system death-on-curing family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56213">
        <property type="protein sequence ID" value="PHX56213"/>
        <property type="gene ID" value="CP500_006510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006440">
        <property type="entry name" value="Doc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39426">
        <property type="entry name" value="PTHR39426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018297">
        <property type="entry name" value="Doc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01550">
        <property type="entry name" value="DOC_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="1">
        <location>
            <begin position="7"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="14486" checksum="633BFD21D6406AFE" modified="2018-01-31" version="1">MPMPNFVSKSIVLSIHARQIEMFGGTPGVRDEGLLESALAQPQATFGGEYLHPTIAAQAAAYLYHIAMNHPFIDGNKRSAFAVTDTFLRLNGFYLNLTDDRVYDLVMQVAEGRMTKEELSTELELCIVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3A8</accession>
    <name>A0A2G4F3A8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trans-splicing intein-formed DNA polymerase III subunit alpha C-terminal partner DnaE-C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56250">
        <property type="protein sequence ID" value="PHX56250"/>
        <property type="gene ID" value="CP500_006480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INTEIN_C_TER" evidence="1">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="534" mass="59959" checksum="CBE2CABEC5C49C43" modified="2018-01-31" version="1">MVKIITKKSLGTQEVYDIGVEKDHNFTLENSLVASNCFNKSHSMAYAYITYQTAYLKANFPVEYMAALLTANSGDQEKVQRYITNCLKLKIDVEPPDINGSELTFTPLPMEMTKGEKHKILFGISAVKNVGEGAIENILEARQEGGDFKSLPDLCDRVNLHSVNRRALEALIQCGAFDKIDHNRQQLVNDLEGVIKWAQDRKKDRESGQGNLFDLLGDTSFGKSANKYESAPKSKTVKDFDKQEKLRLEKELLGFYVSEHPLKNLLQMNQDPDVVTLEQLEDKKGKVSVIVMISAIKPVVTKKGEKMAILQIEDLTHQIKAVVFPKTYEQVGSHITDNAVLLISGKIEKDGEEIQIIVDDAKPVKAVEMSEEFKPLENEDAEIWHPESVKILQVAKPVELLQMVIVKLTPQQIKDTKSLNYLKAILQELSNRGGDGSVSVAGIVVGEYSCQPLRISSQLWVQDGEETVSRLKSAGFDARIFPLNNHGDAMVFREMRDRLNLHSWASCLLDTDRDRISSYLKYLTQSSQITAPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3E7</accession>
    <name>A0A2G4F3E7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_006360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56279">
        <property type="protein sequence ID" value="PHX56279"/>
        <property type="gene ID" value="CP500_006360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013733993" evidence="2">
        <location>
            <begin position="35"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="3">
        <location>
            <begin position="419"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="533" mass="55980" checksum="2D0D8E42C7A9EE9C" modified="2018-01-31" version="1">MVAKNYSRLNTVKGLIVQGLTVSVLAAGSSPAVAQFLPPPPPPPSGSAIPVPAVPGFPSVPANGPANGATNGATSVRSEVYTLGAGDRIQVDIFNVPEYSGPNGQHQVQADGSLSLPLIGSVSVYGMTLEQAANTVKGRYGQYLKRPWITLKLLAPRPLQIAIAGEINRPGAYTISSAAGPGGTAEQMGTQMPTISRALRLAGGITQSADVRQIKIRRPQRNAPEQIINVDLWELLQAGDLRADMTLRDGDTIFIPTVTSLNRQEASTLAVANITGQSTQPINIAVVGEVARPGTYTLAKEATNKLQENESGANSGLLGASETTSGETVLLQTVTRAIKVAGGITPVADIKQIQVRRQTRAGTEQIINVNLWQLLQTGDVSQDLTLQQGDTVIVPKAENIDQAQDAQVNNSTFSPDAIKVTVVGEVVKPGAIALSPNTSLNQALAAAGGFNKARAEMDSIDLIRINPNGTVSRLAIKVNFAATANDPANPQLQNNDVIMVRRSGRAAFSDNVGGTLAPLNPLLGIFRVFDIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3F2</accession>
    <name>A0A2G4F3F2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bacitracin ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_007575</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56007">
        <property type="protein sequence ID" value="PHX56007"/>
        <property type="gene ID" value="CP500_007575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005890">
        <property type="entry name" value="NO3_transporter_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01184">
        <property type="entry name" value="ntrCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="22"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="59"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="279" mass="31550" checksum="6CCF588AF736367F" modified="2018-01-31" version="1">MTQFISTSTKTNDQVNGKSGFLEIDNLFKSYKSVDGKESSVLRNINLNIGENEFISVIGHSGCGKSTLLKIVAGLEKQSSGMVRLEGKEIRKPAADRMMVFQHYGLLPWLTVRENIRLAVDEVLQNLSRPEKISLVNEHLAMVNLTSAADKYPEQISGGMKQRVGIARALAIRPKMLLMDEPFGALDALTRGKLQKQVLDIWEKHKQAVMMITHDVDEAIYMSDRIVLMTNGPAATIGEILSVPFSHPRDRQQLRETNEYYELRNYALNFLDRHFTQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3J3</accession>
    <name>A0A2G4F3J3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Antitoxin VapB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56305">
        <property type="protein sequence ID" value="PHX56305"/>
        <property type="gene ID" value="CP500_006120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019239">
        <property type="entry name" value="VapB_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09957">
        <property type="entry name" value="VapB_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7855" checksum="E5C6B8F4644EDCDC" modified="2018-01-31" version="1">MVTTLEIDKTLLQEALDLSNHPTPTTLIEAALREYIQRRKQLKILELFGTIEYDEDYNYKQQRQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3P2</accession>
    <name>A0A2G4F3P2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IS200/IS605 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56358">
        <property type="protein sequence ID" value="PHX56358"/>
        <property type="gene ID" value="CP500_005810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="2">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="150" mass="17234" checksum="272FAED97B0B3183" modified="2018-01-31" version="1">MAMWRLYYHLVWATKERQPLISPAKETELYSYITGKADTLNCILHAIGGTENHIHLIVSIPPTQSVAEFVKNIKGSSSRHLNQTLQNSNKFAWQEGYGVFSLGQRQLEQAVAYVLNQKEHHLQKTTNSHLEQMTHQDDSPTRWHPNLSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F480</accession>
    <name>A0A2G4F480_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56545">
        <property type="protein sequence ID" value="PHX56545"/>
        <property type="gene ID" value="CP500_004660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7905" checksum="957CA3216B6F03A7" modified="2018-01-31" version="1">MLAAGEVPKCDRSSKPKPLPILIISSYILYPKMRSPERNQTKFIPQRRQTQHNVYGLPQYRDRANAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F489</accession>
    <name>A0A2G4F489_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56555">
        <property type="protein sequence ID" value="PHX56555"/>
        <property type="gene ID" value="CP500_004720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="33861" checksum="50E1F53DBFDA95A1" modified="2018-01-31" version="1">MTASPQPTPESNILGNFASVIGLFGAALFFTGWIYRWSYFSCFQLNVITLDLPVESFFLVPLQVFLGDGWTIVKSAIAFLLTSLAIYHTLWLVNSINKTIATKIYRINRLWRLSARTRGLSLLHRFLKSWQRFNINRYNSIKLLRSLVDEIIIVGWVLLVLFWSAYHQGIADARRDAGENSSLPAVVLIGKEDNIALGRKLNDAFDDKLTLEKYKFIGDKGLFDDWLNKADTDTSNPKEPRVWRLLLERGNWIYLFPALTKEEQKDPKARPPVMAIQQSQSGDQLLIISPAPSQPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4C2</accession>
    <name>A0A2G4F4C2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56561">
        <property type="protein sequence ID" value="PHX56561"/>
        <property type="gene ID" value="CP500_004750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="12413" checksum="62CD3BB0107DDFE5" modified="2018-01-31" version="1">MRRKEEVSAQADESYCLEKLKSIPDISVEIVFTSGGKSKLSRYRALGVQEVWFWEDGLFTLYNLGAEGYDRINRSELVPELDFELLTRCVLMNSIGDAALEFDRAIGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4C3</accession>
    <name>A0A2G4F4C3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cobalamin biosynthesis protein CobD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cobD</name>
        <name evidence="11" type="ORF">CP500_004280</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the CobD/CbiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56633">
        <property type="protein sequence ID" value="PHX56633"/>
        <property type="gene ID" value="CP500_004280"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00024">
        <property type="entry name" value="CobD_CbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004485">
        <property type="entry name" value="Cobalamin_biosynth_CobD/CbiB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34308">
        <property type="entry name" value="PTHR34308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03186">
        <property type="entry name" value="CobD_Cbib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="384" mass="42261" checksum="00E5C0CA6DCDE5DE" modified="2018-01-31" version="1">MMSDEFAVLILAAVLDYSIGDPWGWPHPVQAMGWAIDRYTRLVFNIWNNPPGKRPNLVDSLPGDRPKLLLRCAGIILAIGLILGSYTVSWSIVQAASWVHPLFGIAIASILLASCFAARSLRAAAEDVLTPLNVGDLVKARERLSLYVGRDTENLSQSEILRALLETVTENAVDGVTAPLFYALVGFAIPHLYLLDLSNDYCGTGILPVQNWQFLRCLLSVRNLPIADYSMSMSAIVPLAIAYKAASTLDSTVGYKEAPYTDLGWFSAKLEDVLTWLPCRLTVITLALISGKPLYIWRMCQRDAVKDASPNSGWSECAYAAILGVQLGGTNSYRGVIKHKPLLGDPNQSIAAEHISQAMQLTRYCFLIWLGLSLLFYACFVFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4E1</accession>
    <name>A0A2G4F4E1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Rrf2 family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56632">
        <property type="protein sequence ID" value="PHX56632"/>
        <property type="gene ID" value="CP500_004270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="16497" checksum="5CE0D41972D13118" modified="2018-01-31" version="1">MKLTARGHYSVKALLDLSSQPRFEPTSVKSIAKRQELPAPYLEKLLIEMRRAGLVQSVRGSQGGYKLAREPAQISLGQILEAVGETIEPLARHSPDASLAEDWVTFSLWNQLHKKLVLALYSISLEDLYYDVRSWQAALGEETSFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4F6</accession>
    <name>A0A2G4F4F6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56640">
        <property type="protein sequence ID" value="PHX56640"/>
        <property type="gene ID" value="CP500_004315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="181"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="360" mass="40650" checksum="438DD0DE2825B942" modified="2018-01-31" version="1">MANLRSTVIVKTDICGYTVRVKKLSQSELSRLLNEHKTFISDISIRNEGSLIKGEGDSFWLVFPSVTAAAMAALEMQQELRAQQSSKSNDERLAIRVSITLGDVLHQDKDIFGDTVNLTARIESVTPQDEIYLSQAAWLALNKAEVQTSFVNEFSLKGMSEPEKVYKVDQSHKTRIIENQAIVKADLRGFIAYQESNSIKDVEYLLTNFDAFEKNICEEYGGTIRSIVGDSHLLTFTEAHSALAAMESLCKNWKIFIDNYKIPCGLSVGVTKGNLYIFRSCTYGKDINIADRLEDLSKIVSPATEKNSVIVSDQIKREVSSSKWEYQLIKIDKNAILDNILDYSQFDFFKENDVYRCLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4I3</accession>
    <name>A0A2G4F4I3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56670">
        <property type="protein sequence ID" value="PHX56670"/>
        <property type="gene ID" value="CP500_004030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="123" mass="14214" checksum="1970E7BD9DF770D2" modified="2018-01-31" version="1">MAQFTIEVPDTLLPQLEQLQDRLPTLLMQWLSIANLSKQNITDRSIAYEEVLDFLITQPTPLEIWNFKVSETAQKRLGELLDRNREGGLNESETDELDSYEELDRLMQMLKIRAHSTLLPVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4I5</accession>
    <name>A0A2G4F4I5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56397">
        <property type="protein sequence ID" value="PHX56397"/>
        <property type="gene ID" value="CP500_005650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="141" mass="16190" checksum="EDB533C28E4342FF" modified="2018-01-31" version="1">MNFEEIWQQYDFTESEVLSMGWQFPYDYVLNLNYYWQLTPTNSTSQVATTDQFLNIILKTCIRLEVQLNPNPDELNQKPANLGTIVGWGQISPSPWLENLSLSSHEWLHLLFEIGGNNKIEAVCRSIAIEQLAKQPLALSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4L9</accession>
    <name>A0A2G4F4L9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_003605</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56712">
        <property type="protein sequence ID" value="PHX56712"/>
        <property type="gene ID" value="CP500_003605"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="184"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="424" mass="46080" checksum="45845A8208B20D11" modified="2018-01-31" version="1">MLSVKEAESIVLNLAQPLDSQQDVETVDLLAASGRILAATVTSYLDFPYWDNSAMDGYAVRFADVENCSTEKTVALDIVEEIPAGYQPQYTVQPGQAARIFTGAVMPVGADTVVMQEETRREGDRIFILVSPEKPQAFVRHKGAFYQAGTPLLNPGTIINASEMAVLATAQCIQVPVYRRVRVAIFSTGDELVSPDQPLSPGKLVDSNQYALTVLLTQMGFEVIRLGIILDNQYELTKAITQAISTADVVLSTGGVSVGEYDYVEKILADLGGEIHIRAVAIKPGKPLTVAQFKRDVKTSDSSMMSSDCLYFGLPGNPVSALVCCWRFVVPALRKISGLGSDAWGPEFVRARCNVELRSHGQRETYVWGKLYLVAGVWEFEPAKGSQNSANLINLANTTGLAVLPPTETWILAGEFVEVLKVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4T0</accession>
    <name>A0A2G4F4T0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56803">
        <property type="protein sequence ID" value="PHX56803"/>
        <property type="gene ID" value="CP500_003500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8393" checksum="FADB14EF8B9BEC86" modified="2018-01-31" version="1">MASITIQVDEDIKTAFEGATSETQKQLSYIVQLFLRGNLHNKSLTEVMAEISDKAQQRGLTPEILQQILADDNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4W5</accession>
    <name>A0A2G4F4W5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56765">
        <property type="protein sequence ID" value="PHX56765"/>
        <property type="gene ID" value="CP500_003925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="6205" checksum="96F767C1707A1B86" modified="2018-01-31" version="1">MKEKLSVLVCLLIGVTLGGGFAELSIANPGLANSKTQAADISDPSADLSNVVIPLPRNWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Z8</accession>
    <name>A0A2G4F4Z8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione S-transferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56809">
        <property type="protein sequence ID" value="PHX56809"/>
        <property type="gene ID" value="CP500_003545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041695">
        <property type="entry name" value="GST_C_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044629">
        <property type="entry name" value="GSTL1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44328">
        <property type="entry name" value="PTHR44328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16865">
        <property type="entry name" value="GST_C_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="49"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="404" mass="46259" checksum="5D1087B7C0100872" modified="2018-01-31" version="1">MTPTATIATPLTWTQLEALTDFEVDRTNGPTNAQSRLRLFGKTESDVRVTLYRDNHAWCPYCQKIWLWLEEKQIPYRIEKVTMFCYGEKESWYKRKVPSGMLPAIELDGRIITESDDILIALERVFGPLSLGMENPKVLPLRRLERLLFRAWCTWLCYPANSAKAEQHNRNQFISVVAQVEAALASTPGPYFLAEFGTADVIFTPYVERMNASLFYYKGYSMREENPRFADWFAAMETRPTYRGTQSDFHTHVHDLPPQMGGCYENGEPQMLLNKARVDNGPWAGLPDVMYPEPETSRKEALDRVIKHHRNIIKVNPADDKLFDEALRCALTLMMTGEVCTPPVGSDGALRYLRDRVNVPRDMSIYAAKRLREALEETAALVGDSQGTPILLKHRRDQDPANFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5D7</accession>
    <name>A0A2G4F5D7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56945">
        <property type="protein sequence ID" value="PHX56945"/>
        <property type="gene ID" value="CP500_002915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9329" checksum="DDEDCF748B7CE093" modified="2018-01-31" version="1">METNSMITYKQRLCCWAIARLLPSEQWIIVARFRSRSDADGHFQFLRQTIPHVKFEVVFDLSGDSNRLSALGCPSNPVTSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5J3</accession>
    <name>A0A2G4F5J3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ATP-sensitive inward rectifier potassium channel 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_003815</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56747">
        <property type="protein sequence ID" value="PHX56747"/>
        <property type="gene ID" value="CP500_003815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005242">
        <property type="term" value="F:inward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034765">
        <property type="term" value="P:regulation of ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041647">
        <property type="entry name" value="IRK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016449">
        <property type="entry name" value="K_chnl_inward-rec_Kir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013518">
        <property type="entry name" value="K_chnl_inward-rec_Kir_cyto"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11767">
        <property type="entry name" value="PTHR11767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17655">
        <property type="entry name" value="IRK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01320">
        <property type="entry name" value="KIRCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="12">
        <location>
            <begin position="68"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="IRK_C" evidence="13">
        <location>
            <begin position="142"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX56747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="300" mass="34392" checksum="D86D81972AFB4C6C" modified="2018-01-31" version="1">MKNNRDRQQQARLVSRTGQFSLNVVRLGLPRLHFADLYHSLLTLSWPRFFILIWLSYTLTNSLFALAYLAGGDCITNARPGSFKDAFYFSVQTMATIGYGSMYPRTDYANIIVCIQALFGLWGVAMITGLAFARFSKPTARVVFSRVAVVSPFNGVLTLMYRTANHRSNQILEAQQRVTLIRDEVTSDGEYMRRFYDLQLVRSQSPIFALTWTVMHVIDENSPLYKLTPKDLKEQQAEIVVTLTGIDETVSQTIHARHSFVASEVLWDMRFVDILLRTPEGKRVVDYTRFHEVKAVEEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5R1</accession>
    <name>A0A2G4F5R1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_001930</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57100">
        <property type="protein sequence ID" value="PHX57100"/>
        <property type="gene ID" value="CP500_001930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="331"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="600"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="723" mass="79919" checksum="51D274F20AC03B66" modified="2018-01-31" version="1">MDLQQLMADQELILNQVDNAIALFDSSDSLVLFNKKLAGTWGIAPEWLATKPQSYLLFAEIVDRGYWSLQQSEQFQQALETAKDQNLSFYFEQSNAVCLEVCATITNSGGRLFTFRDVTVHHNSQASLNAEVRRLTFLLGLTERLQNSKSLQEIGRFALNYLVEAMNAAFGDVKVISGKGNDRQAAAISNQVSTQFLASYGEPVAAGMQALLDKGIPYGTGLLWEVVATGKPLFVENYAKHPNAVPQFRHPGIGQLGIFPIAATDGTIIGVLTLESRNVKQLQTAVHQDVLEAACRTLGAAIERAQAQEDLRQVNEQLEYSSQLKSEFLASMSHELRTPLNSILGFSDLLLRQTAGQLSNRQIQYVELIEKSGQHLLQLINDILDLSKIEAGKTELDLQPVRVHELATDCLKMIQPRADKKRIALSLELDYRITKVLIDERRVRQIVINLLSNAIKFTPEQGRVKLSGRLAYGSEINGDYRPDCSPVNASTPYFCFEVKDSGIGIPEDRWHLLFRPFQQVDSSLTKRHEGTGLGLALTKRLAELHGGTVSFQSSCDRGSLFRVWLPLTEMRQELAISAASPLDSGFSSASAMPLPIVSKRILVVEDQPLNQMLISEVLELEGYAVEMIVDGSGMLDRIAATSASPQLLPDLILMDIQLPDVDGFELMRQVKADPVWKSVPMIAVTAMAMPGDRDRCLEAGASDYLSKPLDLNLAIVTVRSFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5W4</accession>
    <name>A0A2G4F5W4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56877">
        <property type="protein sequence ID" value="PHX56877"/>
        <property type="gene ID" value="CP500_003120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="391" mass="44547" checksum="E47801D81289E0F7" modified="2018-01-31" version="1">MDELFRKVFDKCIKFSNDTRKSLLAQIDSFDTYLAGSVSRSEALPMSDLDVVYFGDEGKLDLVEVKNIDRIDDLCIPDENSADLLLLRMSPEAGFLDSVPLNNHHHKYYDKFRSIPHLVSKSLWEYEYSRRFNERSTDGGINMKYSVGGYRDILIINLLARCLLPDRDEDNPEIYQSIEILSAELQLSKVRKKQVLNAIALIMLTKSVVLMAGRTTSSKGQTLLNIGTLNETFRQYSWLSMISLNSPSYLSKYNSAKHVVSKFTLDAANLIKRICKENILESVKIALECAVGSRNISVLDVEKNSELNVFPVFACLIHNPSINSAELERLREIASDDPGHYYTNRLLAKSQNASYHLLCSLKSNARFALDRRTDMRYKSLVANRLERQYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F620</accession>
    <name>A0A2G4F620_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenylosuccinate lyase</fullName>
            <shortName evidence="10">ASL</shortName>
            <ecNumber evidence="4 10">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_001425</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 10"/>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57206">
        <property type="protein sequence ID" value="PHX57206"/>
        <property type="gene ID" value="CP500_001425"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADSL_C" evidence="11">
        <location>
            <begin position="349"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX57206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="431" mass="48424" checksum="7853061E06FA13EC" modified="2018-01-31" version="1">MIERYTLPEMGNIWTETAKLKSWLQVEIAVCEAQAELGYIPAAAVEEIKAKANFDPKRVLEIEAEVRHDMIAFLTNVNEYVGDAGRYIHLGLTSSDVLDTALALQLVASVNILLERVEDLSQAIRYQAQQHRNTVMVGRSHGIHAEPITFGFKLAGWLAEVFRNRARLVNLRSSIAVGKISGAVGTYANIDPRIEAIACQNLGLEPDTASTQVISRDRHAEYVQTLALLAASIERFAVEIRNLQRTDVLEVEEFFSKGQKGSSAMPHKRNPIRSERLTGMARIVRANAVAALENVALWHERDISHSSVERMILPDSSTVTHFMLVETTDLVKNLLVYPENMKRNMNLYGGVIFSQRVMLALVEKGTSREDAYKIVQSCAHEAWNKTGGNFYNLIAKDERVTAKMTSKEIDDCFDPQYQLRHLDLVYQRLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F693</accession>
    <name>A0A2G4F693_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57245">
        <property type="protein sequence ID" value="PHX57245"/>
        <property type="gene ID" value="CP500_000975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="13014" checksum="BA8923922290237C" modified="2018-01-31" version="1">MDKVSFYRQYIQELLTERAERRSPKDPVSSETIFDRVSDRYQLVHVGWKDSNTRIYGCIIHVDIKDGKIWVQYDGTEEAIANQLIARGVPSQEIVLAYHAPHVRKYTEFAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6D4</accession>
    <name>A0A2G4F6D4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4926 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57354">
        <property type="protein sequence ID" value="PHX57354"/>
        <property type="gene ID" value="CP500_000815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032568">
        <property type="entry name" value="DUF4926"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16277">
        <property type="entry name" value="DUF4926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="7993" checksum="35E13B73E68BA1D4" modified="2018-01-31" version="1">MIQELDSVVLTIDIPEQNLSQGDIGTVVLVHQGGVGYEVEFVTLTGKTVAIISLFSSQVRLIGDREIAHARMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6F6</accession>
    <name>A0A2G4F6F6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Low-complexity tail membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57374">
        <property type="protein sequence ID" value="PHX57374"/>
        <property type="gene ID" value="CP500_000060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="202" mass="22185" checksum="1BF5A3779E4FED94" modified="2018-01-31" version="1">MRSFWSEPFLWIHLAGVAALPIFLGLCLLGLAVGAPLLPVWLEVFLVGAAGIGPVLWMQWFRPFYIFSILVVAVKPQNLSNAQQRILLGFKSRLNQGLALFVAIVLAVILWQLYRFAPLAAGVTPFPPQWRLAGLLLAAFAFLASNLFLQVPASVMAVLLKPESDFAAMQPDVLEKIGQDFTIAGWQVDRILPAFVAEEDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6I4</accession>
    <name>A0A2G4F6I4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two-component system response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_000100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57382">
        <property type="protein sequence ID" value="PHX57382"/>
        <property type="gene ID" value="CP500_000100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="25"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="136"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="35034" checksum="5506731AD2E0399B" modified="2018-01-31" version="1">MDNAIPELDQIKRQLMTLNRPKKPKMLVVDDEPDNLDLLYRTFRRDFNVLKAESGIRALEVLESEGEVAVIISDQRMPEMKGTEFLSKTVFQFPNTVRIILTGFTDIEDLVDAINSGQVYKYITKPWDPNELKMVVQKAADTYEVLKQRTEELRQAQNQIQLLATIMQTALDYPNLAATLEPIATAISDNFLADTCILQLVEGNVLTPVQGCHTSGGELQNWLADDPLVQQAIVSRNIQAALNIATDASLSSLPHYQKSGIKSHLSIPVVHGGRSLALISLQWKQPCTLRPDEITTIHLSAQQVALVMTSFQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6I9</accession>
    <name>A0A2G4F6I9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription termination/antitermination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">nusA</name>
        <name evidence="9" type="ORF">CP500_000040</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates in both transcription termination and antitermination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57370">
        <property type="protein sequence ID" value="PHX57370"/>
        <property type="gene ID" value="CP500_000040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_B">
        <property type="entry name" value="NusA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036555">
        <property type="entry name" value="NusA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013735">
        <property type="entry name" value="TF_NusA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010213">
        <property type="entry name" value="Tscrpt_termination_fac_NusA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08529">
        <property type="entry name" value="NusA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69705">
        <property type="entry name" value="SSF69705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01953">
        <property type="entry name" value="NusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="KH" evidence="8">
        <location>
            <begin position="259"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="KH" evidence="8">
        <location>
            <begin position="331"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="398"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="425" mass="47561" checksum="9A02EE9EB83AD77B" modified="2018-01-31" version="1">MSMVPLPGLKEMVEGISKERNLPQHAVQAALREALLKGYERYRRTQKLDHFSEEYFDNFDVELDAEQEGFRVLANKTIVEEVVYPDHEIALSEVQEVATEAQPGSIVLVDVTPNQKEFGRMAAIQTKQVLAQKLRDQQRKMIQEEFKDLEETVLQARVLRFERQSVILAVTSSFGQPEVDAELPKREQLPNDNYRANATFKVYLKKVGEGSTRGPQLLVSRADAGLVVYLFANEVPEIEDGVVRIVAVAREANPPSRHVGPRTKIAVDTLDRDVDPVGACIGARGSRIQVVVNELRGEKIDVIRWSPDPATYIANALSPARVDEVRLVAPEGRRAHILVAEDQLSLAIGKEGQNVRLAARLTGWKIDIKDIAKYDRDAEDSKLAAEETRLDELAAQEEAEFDGDMKGLESEQEEVATMDENEVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6J9</accession>
    <name>A0A2G4F6J9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57321">
        <property type="protein sequence ID" value="PHX57321"/>
        <property type="gene ID" value="CP500_000635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="96" mass="10846" checksum="88C831F5DD22850D" modified="2018-01-31" version="1">MLNLSHSRPLNQFQQEAPELLHQFETDKTPIVITINGKAVAVLQDAESYEKLLNRLELLESLAGIRQSLGEFDQGKGVSIHQAFEELLPTTNYIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6R3</accession>
    <name>A0A2G4F6R3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine-protein kinase PknK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_000165</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57391">
        <property type="protein sequence ID" value="PHX57391"/>
        <property type="gene ID" value="CP500_000165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="7"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="1578"/>
            <end position="1833"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1528"/>
            <end position="1569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1837" mass="207001" checksum="B058A5BC016D8995" modified="2018-01-31" version="1">MIAIPGVAVLALIYESSTSLVYRGRDEQNNQPVIIKLIKEDYPTPEELNRYRREYQITASLKLDGVVTVHKLLYVRNSLAMILEDFGGESLRIFIASQKLTILGFLTIAIKVAETLGEIHSKNVVHQDINPGNIVFNPATGQIKLIDFSISSVSESENIPSKDPNFLEGTLAYMSPEQTGRTNRVIDYRTDFYSLGVTFYEVLAGQLPFNTADPMELVHCHIAKQPVPLHETISEVPQAISDIVMKLLAKTADERYQSAWGLKADLESCLFQLQTAGLISEFTLGSQDISDKFKIPQKLYGRQREVETLLAAFERVAVTNNRFSRRNEQFQTSSLNREATSRTETSQLLLTRREHKSRSEMMLIAGYSGIGKSAMVKILEKPITRRQGYFIWGKFDQYKRTIPYSAIVIAFSELVRQLLTESEVQLAVWREKLRSAFGQNGQIIIDVIPEVELIVGSQSPVVELGPTESLNRFNLVFQNFIRVFCQPEHPLVIFLDDLQWADSATLKLIELMMTDEATQYLFLIGAYRDNEVSPTHPLMMTVETLRNQEAIVNQITLSPLEVDNITHLIAETLHSDRESVKPLAELVVSKTDGNPFFVNQFLHTLYQEDLLTFHPPLSGSKGGWHWDMTQIEQCAITDNVVDLMVQKIRKLPTSTQQILRLAACLGNEFDLNTLSLINEQEASETFAQLLPAINCGLILPSSELERKSLDYVMFPLLILNYKFLHDRVQQAAYALIDDSQKKAVHLKIGRQILENTPAQYRADRIFELVDHLNVARTLIGEDRELIELATLNLDAARRAKDATAYVSALQYLTAGMDGLTEDIWDSHYDLAFALHMERANVEYLNGYFEKSEVFINITLQKARSPLEKVEIYNLLIVQYTLRAKYEDAVKAGIKALNLLGIDLPLDGLQTVIYEEFEAAKSILGDREIASLINAPEMTVPDKKVAVKLITNLLTSAYLNNPDLWKVSVLKGLNLSLKYGLVPEASLCYAGYGMFLNAVSGDYKTAYQFAMLSLNLSEKSGNLGLKCRACSSLVSIFHYWFNHIKEAYAISNEGYQAALESGDLEYAGYLLSNRIANYCFQGRDIAQVLADTKGYLQFSQKTKNQLVTDTLLGVELILRNLSKLTNDKLVFENEEITEVEYVYNCQSHQNLYSLCLYQIRKCQVLYLYGNYDEALQLALEVEKQLSFITGAIPATEWNFYFSLVLIAVYPNVSKPEQTLYLEKLEINQTQMKIWAENCPENFLHKYVLVQAEIARIYRKDSEAVELYDFAITLAQDNEFVQNEALGNELAAKYWLNKGKYQYAKIHLRDAHSCYQRWGAARKVDDLEQKYPLLREMTPLNGNFSLNQTTTTIHTSTGSDARALDLATVMKASLAISSEIVLDKLLASLMRISLENAGAQLGFLILVKDGKLLILAKASVFDEDVAMLPFTPLEECQDLPVTVINYVERTRLDLVLNNAAAEGLFTADPYIAKHQLQSILCTPIVNRGKLIGILYLENNLTIGAFTPHRLEVLRLLSSQVAISLENALLYNSVEQKVQERTQELNEKNESLEQTLRELKSTQAQLIQTEKMSSLGQMVAGVAHEINNPVSFIYGNLTPASEYVQDLLKLIELYQQHYPEPSDEILDEIETIELDFLIEDLQKLLDSMKVGAERIRDIVLSLRNFSRLDEAQMKSVDIHQGIDSTVMLLQPRLRKEGGRLGIEVIKNYAKLPLITCYASQLNQVFMNILTNAIDALLSVRDCPEDYQHKPAITITTEVTERNSVIIRMADTGPGMSAEVLHKIFDPFFTTKPVGSGTGLGLSISHSIVVSSHGGKFSCVSAPGEGSEFIIEIPIAPRQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6R9</accession>
    <name>A0A2G4F6R9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57415">
        <property type="protein sequence ID" value="PHX57415"/>
        <property type="gene ID" value="CP500_000305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7067" checksum="439B835960B7C520" modified="2018-01-31" version="1">MGQRLCCAHSAGGGTSMNDVFALYETDYYLWLQETYQTLEKKERVKLIVSAIAWDLSLMTCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUC0</accession>
    <name>A0A2G4EUC0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_023090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000264">
        <property type="protein sequence ID" value="PHX53142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53142">
        <property type="protein sequence ID" value="PHX53142"/>
        <property type="gene ID" value="CP500_023090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="291"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="408" mass="42056" checksum="9371A49F51DEA1FA" modified="2018-01-31" version="1">MKSSTGKFWKQPAIYILLLVTGAGAAMLGDRLTASRLPANSGEPQRTLEPKLQLPLNAKPQASKGLPPNSVSGNRANVNFIVAAVEKVGPAVVRIDASRAVKPGSRGLSPEDFFGRGQGGVERGTGSGFVIGADGVILTNAHVVEGADTTVSVTLRDGRSFTGRVLGADKVTDVAVVKIDATNVPVVTIGNSDKLLSGEWAIAIGNPLGLDNSVTAGIISATGRSSSDVGVPDKRVGFIQTDAAINPGNSGGPLLNSTGQVIGMNTAIIQGAQGLGFAIPIKTAQQVAQELISTGKVEHAYLGIEMATLTPDVKEQINKNGNSSLRVTVDRGVAIVSVVPASPAAASGLRAGDVIQKINNQPIIQSEAVQEFVQNARVGGLLQMEINRNGQILNLSVKPGSLPVQKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUJ6</accession>
    <name>A0A2G4EUJ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000243">
        <property type="protein sequence ID" value="PHX53205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53205">
        <property type="protein sequence ID" value="PHX53205"/>
        <property type="gene ID" value="CP500_022730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="14393" checksum="002545A699FEF1F6" modified="2018-01-31" version="1">MKTVLIVEDDLVNARVFSKILTKRGGLAVKHTENVEEVMQIASKGEADLILMDVSLSRSVYQGKAVDGIKITQLLKADPQTASLPIILVTAHAMAGDRETFLHQSGADGYISKPVVDHQEFVNQIIALLPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUL7</accession>
    <name>A0A2G4EUL7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000234">
        <property type="protein sequence ID" value="PHX53233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53233">
        <property type="protein sequence ID" value="PHX53233"/>
        <property type="gene ID" value="CP500_022560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="8758" checksum="E29D90AAF90E0A06" modified="2018-01-31" version="1" fragment="single">ASGIGHRALPITNYLLPILDRNILIALAVAIILRGCDRVSIRRKSASSGKICSQELPRELTLSKIIEMISTIDGTKSSRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUN7</accession>
    <name>A0A2G4EUN7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS4 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000228">
        <property type="protein sequence ID" value="PHX53262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53262">
        <property type="protein sequence ID" value="PHX53262"/>
        <property type="gene ID" value="CP500_022440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="129"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="439" mass="50259" checksum="19E262A8A7BE6D11" modified="2018-01-31" version="1">MVEDEVIASQLSALLTPAITSQENYYRQLGLRARILNLPLMVAAVLTLLWRDVAGVTELTRMLARSGFLWCRPTTVTQQAMSQRFLSFPATLFEGVFKNLLPSLRTAWYQRNQRPLPESVQFALTKFSRIWIVDSSTLEALFCKLKSLEDIPKGQLAGKMATVIDLMTRLPVDIWFLENPRASDVKLEENILQLVSSKTLLLLDRGFYHFSFWLKLIERDIHLITRLKKGAAIQVKQVFTKSYDLKDSLVRLGSGTAKTPFITLRLIEVRSGKTWHSYLTSVLDPQVLPPYVVADLYRRRWRIEEAFNTVKRLLGLSYLWTGSLNGIQLQIWGTWIFYAILVDLGDTVADQLSLPIDSISLEMIYRGLYHFYVARQQGKATDPIEYFTAPENRDLGIVKSQRKPNVKLIVAPFPDRQRGSDRYFFETSAQTPLTTAIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUR8</accession>
    <name>A0A2G4EUR8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar assembly protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000225">
        <property type="protein sequence ID" value="PHX53274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53274">
        <property type="protein sequence ID" value="PHX53274"/>
        <property type="gene ID" value="CP500_022380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="406" mass="46014" checksum="4EFB4C713A02F515" modified="2018-01-31" version="1">MTRFIHDRFAKEFLEELLSPIGTVNIGRDVTSEVREIDVYFIPGVEIPEYSISLGLLGKMAGKTAIFEPFRNPVTIKEVWSCMSKLWGLQSELERQARRENTRLNDGKLPRLWILTPTASKELLEGFGGVQNPENWLEGIYVFPKHWRGAIVVIHQLPEIPETLWLRILGKGKVQERAIGELGALAMDDPLRMIALELLYRLQSHLVVENQREPEPEERELIMAIAPLFQQQLQAAEQQGLERGLERGLERGLERGLERGLEQGIEQGIEQGIEQGIEQGIEQGIEQGRQAQQRLILENFLQVRFGELSQRMTVFLSPISKLLAADFTMLLVAISMLTVDEAGREQAVRLLAEKVLTMRQNELGDILSTALTNLLALPVTELTLLVEQLPQLSADELRERLGRIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUS6</accession>
    <name>A0A2G4EUS6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000240">
        <property type="protein sequence ID" value="PHX53216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53216">
        <property type="protein sequence ID" value="PHX53216"/>
        <property type="gene ID" value="CP500_022685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="442" mass="49764" checksum="2C9B6C6C3A63E02C" modified="2018-01-31" version="1">MEKLLAQAWNLKQNLIDFVLESEGELAVALETYVADRSSRERYDIAHQNQIVDSFTVEGKVGSQTPIDLFVANQSDLTEGDRNLLESWQHRSFTGLFEISQISPDSWDLMNWLTAKHYTVKPNSPNLLQEMSRFKLGEILLTRIAPLTDNCWILSGPPIPMGKLGKPKLAVAIGNFKQNYPKSLYSDAPELLEQAWHSVEQYHVDFTEFFGSDELTLSGYHLNKQLAEFQEFITKKRLADLGFDETKSLAQIVEDAGVDRAEVKAAAIAASGADAKTVEVAIDSNSKMVTPKVELPDRFKKAEQVTALSHPRWGQTFLSTYTQFTAMLAAADFASVPDGEKLVRNYLEDPAINAWIWQRLAKVDPAKLAQILQTVLERTDFQLDRDLDSLLQEFKKPLEPELPEIASVPQHLHNLFQQALGEVNKSKSKPQEKNKSSKGFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUU4</accession>
    <name>A0A2G4EUU4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000228">
        <property type="protein sequence ID" value="PHX53258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53258">
        <property type="protein sequence ID" value="PHX53258"/>
        <property type="gene ID" value="CP500_022455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8350" checksum="FE7A15C0EF333A72" modified="2018-01-31" version="1">METDLHPQPHQAFWLGKQNWVLFNFSKIRRFANTNCQIFSKNFSVTRSRHLEDVKTGIAQFLSYRLGVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUV1</accession>
    <name>A0A2G4EUV1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000242">
        <property type="protein sequence ID" value="PHX53210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53210">
        <property type="protein sequence ID" value="PHX53210"/>
        <property type="gene ID" value="CP500_022720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="7637" checksum="02681C2E31A9EB71" modified="2018-01-31" version="1">MNQVFDKIEKILCETWKETGFGKVTIESERREHGKGKIQVTVKGSTFYRYHISEEDVREWNSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUW0</accession>
    <name>A0A2G4EUW0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000238">
        <property type="protein sequence ID" value="PHX53220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53220">
        <property type="protein sequence ID" value="PHX53220"/>
        <property type="gene ID" value="CP500_022660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7769" checksum="7FD12F502E7A22FD" modified="2018-01-31" version="1">MNIEENATVTDSSNKVSLPKSKEELLGEQTEKALGQQKQGNAKTMRAVEQFKEEMQHKIDEECHHKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUZ3</accession>
    <name>A0A2G4EUZ3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Biotin synthase</fullName>
            <ecNumber evidence="3 13">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">bioB</name>
        <name evidence="16" type="ORF">CP500_021935</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22060"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="EC" id="2.8.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="3 13"/>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53359">
        <property type="protein sequence ID" value="PHX53359"/>
        <property type="gene ID" value="CP500_021935"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="PTHR22976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 13 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 13" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="71"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001619-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX53359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="363" mass="39311" checksum="4402B6933AAA9EEB" modified="2018-01-31" version="1">MVQAPLSTFSKSSIDLLPEKSPLQQRLDSLVEQIITGYRIDRDEALALTEIEGQENILLLCSAADRVRQACCGNTVDLCSIINIKSGNCSENCGFCSQSAHHPGENVPIYGLKTSDEILAQAKAAEEAGAKRFCLVSQGKGLKHNSPKSSEFDQILDTVRRIIDETNIKPCCALGEVSVEQAQELRAAGVTRYNHNLESSEQFFPNIVTTHQWSDRTATIKNLKAAGIQACSGGIIGMGESWEDRIDLALSLRELEVESVPVNLLSPRKGTPLGDVPQLNPYEALKAIAIFRLTLPEQIIRYAGGREAVMGELQHLGLKAGINAMLVGHYLTTMGQPAEQDRAMLESLGLQGGEAPIPGSFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV23</accession>
    <name>A0A2G4EV23_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000205">
        <property type="protein sequence ID" value="PHX53381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53381">
        <property type="protein sequence ID" value="PHX53381"/>
        <property type="gene ID" value="CP500_021780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="510" mass="58106" checksum="78B3455E9D46CE76" modified="2018-01-31" version="1">MKTDYLIVGSGLSALVFGALMANSGKIVHILEAHEHPGGFGHTFTMAKKYTFNAQFHYVWDCGEGHTVNRVLKKLGLDREVTFERYDPNGYDHMRMPGYALDIPSEPAELIRRLSALFPEASENIRKFVNEVEQTGAGLRKLAPPVKPIELLKNFGDVFCAIQHLNSTLQDVFDKFQLPQAAQTLLALQWPDFLLPPNQLSFYAWIALFRGYQEGAFYPTQHFEDVINSLVKVIESHGGQVLLNHEVTNFQVTNRTVTGVEAMDLTTHQTHEFTGKTVICNLDPKRAAKMIGEELFSKTVQRKLNYEYSASNYMVYCVVKGIDLRDYGFGKWNTFHSEHLDLNESFAQMYNKNDFSHPSFAITTPTLLTEASRDCPEDCQIVEFLTVANYGYFKQLWESDRKAYRKKKQEILDSILDVVEKHYVPNFRKHMVFHITGSPTTNERFCWCPNGNSYGSILTPRNIGRDRLNHETSLNNFYFCNASSGYPGFAPTFWTGALLYQRLSGDAILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV98</accession>
    <name>A0A2G4EV98_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000194">
        <property type="protein sequence ID" value="PHX53463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53463">
        <property type="protein sequence ID" value="PHX53463"/>
        <property type="gene ID" value="CP500_021400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SH3b" evidence="2">
        <location>
            <begin position="94"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="153" mass="16423" checksum="FCE828D036B217B5" modified="2018-01-31" version="1">MSSIYSFFKFLVGFLLAIVLMTGASVAAALYIAAKLTTLPERPVFPNDKTAVQIAGVKPTATAKASPVSDSSDTPSPKPLEPGTYRALITQPIGLILRDSASRDANRIGGVGYKEKVVVLEDSPDKEWQRIRVEDGSRDGWVKGGNTEKIEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVA8</accession>
    <name>A0A2G4EVA8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MORN motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000203">
        <property type="protein sequence ID" value="PHX53396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53396">
        <property type="protein sequence ID" value="PHX53396"/>
        <property type="gene ID" value="CP500_021720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="25481" checksum="144C30BDBB33896F" modified="2018-01-31" version="1">MISRFKTSGIAILAVSVLEIGSYATYPLPSIAQQVGVGAPSGRCVPAIATGRVSCDYDSGDSYIGDFVNGLPSGTGVYIYSSGDRYEGQFRLGQPNGRGQFIFKDDARVEGVFRDGKISSGTAIFTNGDRYVGAFSLDRKAGTPTGQGQFIFVNGDRFVGQFLGGKPLGAGVFTRADGTRCSGQFFNQELDARGTCAFSNGIRYEGEFRKGLPHGKGIIIDTSGKRFPGVFKDGQRLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVF7</accession>
    <name>A0A2G4EVF7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000184">
        <property type="protein sequence ID" value="PHX53521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53521">
        <property type="protein sequence ID" value="PHX53521"/>
        <property type="gene ID" value="CP500_021055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="6"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="15055" checksum="7D7CE0386A2BC834" modified="2018-01-31" version="1">MIERVRLYSNENFPIAMVEHLRSLDCDVLTSYDASQANQGIPDDEVLRFATAQNRAVISFNRDDFVALHRGGDRHAGIIVCKDDRDYLGQVTILHAYLQQVDSLLDRLIRIKKQNQRGLSHPVFVVQEYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVK7</accession>
    <name>A0A2G4EVK7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="13">ASA dehydrogenase</shortName>
            <shortName evidence="13">ASADH</shortName>
            <ecNumber evidence="7 13">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">asd</name>
        <name evidence="15" type="ORF">CP500_021150</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7 13"/>
    <dbReference type="EMBL" id="NXIB02000187">
        <property type="protein sequence ID" value="PHX53508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53508">
        <property type="protein sequence ID" value="PHX53508"/>
        <property type="gene ID" value="CP500_021150"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005986">
        <property type="entry name" value="Asp_semialdehyde_DH_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01296">
        <property type="entry name" value="asd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12 13" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="14">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="13">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="41"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="160"/>
            <end position="161"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX53508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="350" mass="37661" checksum="3E7731554D844476" modified="2018-01-31" version="1">MSQSYRVAILGATGAVGAELLELLHSRNFPLAELKLLASERSAGSKLPFGGEMLTVEAVEARSFDNVDLVLASAGGSTSKFWAPKAVAAGAVVIDNSSAFRMDATVPLVIPEVNPEAVGSHRGIIANPNCTTILMAVAVWPLHKVRPLKRIVVATYQSASGAGARAMEEMKAQARAILAGETPKTDIFPYPLAFNLFPHNTPINDLGYCEEEMKMVNETRKIFGTDEIKISATCIRVPVLRAHSEAINLEFAEPFSAIEAREILNQAKGVKLVEDWQANYFPMPAEASGKDEVLVGRIRQDISHPCGLEMWLSGDQIRKGAALNAVQIAELLVAKKLLQTQGATASNSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVQ1</accession>
    <name>A0A2G4EVQ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000173">
        <property type="protein sequence ID" value="PHX53609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53609">
        <property type="protein sequence ID" value="PHX53609"/>
        <property type="gene ID" value="CP500_020580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="331" mass="36955" checksum="23886755567DFB48" modified="2018-01-31" version="1">MGNLRFKSPANQYRWIALGSFAVIMGISGALAYRLAPPPGFMAQGILSSNSPPVKFSSTGTTILKQGEQLTPDILLADNVVKAVADAVKLSPQQVRENASVKISKPEQPLEIAVGYRSLDQEQAIKTADMLMKGMVEKSRLINQYRWQSVNQSLNQRLAQVTQELKQAQQKLDQYEREKARLLQQIKVQQDFYNKTQLAMADTQASEKEMVSSFAAAQVPQIVATPTSDPTVPLILGIGLLLAILVSRGLIPTVGNWRYKAAFQREESDRLQSALYRLIKEGNGEITLVRFAMETRMSPDVAQRFLNEQAEVFNAHCEIKDDGSIFYHFHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVW9</accession>
    <name>A0A2G4EVW9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000170">
        <property type="protein sequence ID" value="PHX53628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53628">
        <property type="protein sequence ID" value="PHX53628"/>
        <property type="gene ID" value="CP500_020465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="383" mass="39781" checksum="5082891D2E12BB7F" modified="2018-01-31" version="1">MTSQIENNSGIIRASHIGDNIPGELRKKIDNSQPGAANITGANYLTITPEPKAITPNGETVGQEINLDAIAKHIKSTADGEINKDTIEISPDLLGNSVKTKGADPLNFETLTIRPFTIKVNDFGEANIISDPSKLDSLSGIVNAAAQGAKENRFFDADDADNVIEITPEDAPQSGGLRAWGGNDRILGTNGNDTASGGTGDDTIVGARGIDLLRGGQGSDLIDGGEGDDIITGDRGDDYLLGGLGDDIIRGGGANDFLIGNAGNDILIGDVGSDFLMGGEGADQFILRGDTFTPAAAFADRIFDFKPSEGDIIKIAYLKGTQGMDEIIFAAVDVNKDGITDTAILCDCGDVVGVILSTDPTKANLRNSIFMAGPLDTTLGKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW95</accession>
    <name>A0A2G4EW95_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53799">
        <property type="protein sequence ID" value="PHX53799"/>
        <property type="gene ID" value="CP500_019460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="33"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="35167" checksum="FE59E5073F5960C6" modified="2018-01-31" version="1">MYQTEQSPTPKNVLPTMYDLPSEHPEDSGLPDLYHLWQSRCLEYTFRPSNYPIELVFVASDLNLYFDVRHTQWYKRPDWFGVVGIDRFYQTQELRKSYVIWQEEVSPFVVVELLSPGTENEDLGQTIRGLGQPPTKWQVYEQILRVPYYIVFDGATNNLRAFVLTGDRYEELILAEPRVWMPEIQLGLGLWLGTFEGLERSWLRWYDANGSWVPTPTEQQRQQKELAQQQAEQARQQAEQQRQQTEVAQQQAEQQRQEKELAQQQTEQQRQEKELAQQRTQRLAERLRAMGIDPDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWR9</accession>
    <name>A0A2G4EWR9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_018585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53983">
        <property type="protein sequence ID" value="PHX53983"/>
        <property type="gene ID" value="CP500_018585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045223">
        <property type="entry name" value="Asc1/RACK1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19868">
        <property type="entry name" value="PTHR19868"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="13"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="327"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="379"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="421"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="463"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="505"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="547"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="589"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="623" mass="68486" checksum="831C0CFB5FDF415B" modified="2018-01-31" version="1">MFIMIGQLLKERYQVTEKLGQGGQAITYKAKDTQGQNQIRVVKHLCPTSTNPTLSEAAKHDLWETAKELFGKEAKALAGLGHHPQIPGLLEDFVENGEFYLVQEFIEGQPLSVELPSGQRWSETQVIQLLHEILSILEFVHSKGVIHRDIKPDNIIRRRLDNKLVLVDFGAVKLERQLAQVSAKSRRSVSVGTLGYMPSEQQDGKPVFASDLYALGMISIQALTGKNAADLVLHHKKRGEIDWQPLVTVSKELTEVLTGIVRCFPEDRYQSAEEVLQALNPNGSKINNGGYTPTEIVSEPPKVPPDYRTERVEQPPKIQDWRCIHHLTGHVASVRSVAISPDSQTLVSAGDDNTVKVWHLNSGVSGSLKNTFKPQTGFFKGEATYFTSVAISPEGQILASGCLDKTIKLWHLNNGNWIRDLKGHSDSVYSVAISPDSQTLVSAGRENTIKVWNLPTGQALRNLTGHSDSVYAVAISPDSQTLVSASRDNTIKVWNLLNGKLLNTFTGHIDWVHCVAISPDGQTIVSGSKDNTIRLWNIGSGQLIRTLNGHSNWVTSVAISPDGSTLISGSRDKTIKLWNLDNGELIATLTGHLELVWCVVISPDGKSIASSSDDGAIKIWQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWS2</accession>
    <name>A0A2G4EWS2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000172">
        <property type="protein sequence ID" value="PHX53617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53617">
        <property type="protein sequence ID" value="PHX53617"/>
        <property type="gene ID" value="CP500_020550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="381" mass="43389" checksum="0E6009A8BDEC9330" modified="2018-01-31" version="1">MKANPGGEIASAEVMGRDNLISDLWGILEQQSVMLSAERRMGKTSVIKKMRAEASPDKLPIYRDLEDVKSPIEFVNTVFQDVKAYLTPLKRTTKKTHELLTKLGGAEFSGIKLPEIAAAHWKELLTVTIADLVENQDSTLIFFWDELPYMLRNIGDEAAMELLDTLRSIRQMYPRVRMVYTGSIGLHHVIADLRKVGYTNDPTNDMYAQDVPPLSAKDATTLARKLLEGENIVTPDIQGTAVAIADELSNIPFYIHHLVVKLKLRGGSGDIPAIKAIIADSLDDPMNPWKMEHYAERIDSYYDEKQRPYARNLLDILAVANQPLLFDELFNRLKQESDTQDKEIARKVLTLLQKDYYIQKGDLGFQFRYPLIQKYWKSLRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWS5</accession>
    <name>A0A2G4EWS5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Proline hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_018940</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000141">
        <property type="protein sequence ID" value="PHX53916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53916">
        <property type="protein sequence ID" value="PHX53916"/>
        <property type="gene ID" value="CP500_018940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="194"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="312" mass="35545" checksum="003F0B68E29C880A" modified="2018-01-31" version="1">MTYTQPQIKPQDVKVKILLTGGHQCTVTLKSDTPLLHSLVKTLVDRTQQNPGFSTLFQIPIDEGRSALYFPGEHLVGLVTEPPIYLPQLQPQQPEIPVEIPLEIPLEIPTPAPVNEELISRYAQIDNFLTVAEKNKLIKYVLAKESAFVTTSTSTNADDYRRSMVLHSFPEFSELMINRIKAILPDVLRKLNIPSFSVGDIETQLTMHNDNNYYKLHNDSGSPDTATRFFTYVYYFNREPKAFSGGELQIYDSKIENNFYVAADSFKTVEPRNNSIVFFLSRYMHEVLPVSCPSKAFADSRFTINGWVRRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWT2</accession>
    <name>A0A2G4EWT2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54005">
        <property type="protein sequence ID" value="PHX54005"/>
        <property type="gene ID" value="CP500_018370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8019" checksum="D77465152B53555E" modified="2018-01-31" version="1">MLTTPIVHSDPDILGGTPVFMGTRVPMKTLLDYLEAGDSLNEFLDHFPSVRRDQAISVLELAKEMLTAYATPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWV9</accession>
    <name>A0A2G4EWV9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="5">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queA</name>
        <name evidence="6" type="ORF">CP500_018410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the QueA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54023">
        <property type="protein sequence ID" value="PHX54023"/>
        <property type="gene ID" value="CP500_018410"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="384" mass="42691" checksum="B98084654C264EB2" modified="2018-01-31" version="1">MTEIDWSLDGYDYELPPDRIAQNPVVPRDSSRLLVVDSPSSQQHRIFRDLPDLLNPGDLLVLNNTRVIPARLYGHKPNGPAVEILLMEERQHNCWLALVKPGKRLKLGAKIEFDPICNEESAGPCCCLSQATATLSDRLTATVIERDDATGGRLLEFNLPTEMSLIPFLDEYGHVPLPPYIDNSQAAPEQYQTVYADRLGAIAAPTAGLHFTKELFSRLEQRGIETTFVTLHVGVGTFRPVEVEDVTTHKMHGEWVEVSPATVEKIRETKARGGRIIAVGTTAVRALEGAAAATETPIGDFPLQPFSGQTNLFIYPGYKWRVVDGMITNFHLPRSTLLMMLSAMIGRSRVLDLYLEAIAQQYRFYSFGDAMLILPEAVFDQIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX43</accession>
    <name>A0A2G4EX43_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000129">
        <property type="protein sequence ID" value="PHX54048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54048">
        <property type="protein sequence ID" value="PHX54048"/>
        <property type="gene ID" value="CP500_018190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="169"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="319" mass="36422" checksum="619F1EA8BE416126" modified="2018-01-31" version="1">MTTLKMRSYGGESDWCAIANLIEICEAIDKLGEEVSATELKLILDAPKLDKARDVQLWEDGNYKLIGLALLDMPDSQDEIDACLWFYVHPNVRGESLEKDIIKWGETRLRQVGKAQNLPAKLRTYSREDKTNQIMLLEKQGFEVDRYFWTMARSLSDPIPTPEFPADFVLTHVSGEKDIQPWVEMFNQSFIDHWNHHDLTAETVRYWMQDPNYQPELDLIAVSGDRQFAAFCDCQIKAQKHTNSSTKDGWIELLGTRRDYRKMGLGKAMLLAGLHRLQAAGANTAKLSVDADSLTGATKLYKSVGFRPMETWIEWAKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX50</accession>
    <name>A0A2G4EX50_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000124">
        <property type="protein sequence ID" value="PHX54114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54114">
        <property type="protein sequence ID" value="PHX54114"/>
        <property type="gene ID" value="CP500_017895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="83" mass="9651" checksum="7DD114B225C24996" modified="2018-01-31" version="1">MSEQKPISPWNYKPWWCQPWSILLTGTSLISASWLLLKTVWITVLVAIPLLAWMGFFLLVWPKLMLDSGLLEKYQESEIKGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX67</accession>
    <name>A0A2G4EX67_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000122">
        <property type="protein sequence ID" value="PHX54134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54134">
        <property type="protein sequence ID" value="PHX54134"/>
        <property type="gene ID" value="CP500_017780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="35"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="190"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1300" mass="150363" checksum="CF29ED3EC125E696" modified="2018-01-31" version="1">MSQTMASRSVRIDGAGLDKVRQRMAELEKPLNPDKRGWSQENLEEQAHVSLSTIKRFLEGTPRDRSKVILILKALEFKPIEFIAEHDSNLHNSELEPQQNIAIDWQRVCQSMLKEQQEEQRFRRRATEMGFEVNVFVPLGLIERKQQQRRSGNVPMELLHQLEPEVVTRIYEHDEFMTDVIGQNPTGKNKHIAIVGEPGAGKTTLLDKIATHIQENDRDLPICIALASLQGKTLKDYILQEWLPEAMALVYPDIDVEKSHKTSLQKRLRQGGVWLLLDGVDEMAVGANSCLSLEEIRNQLTDWLGNVRVVLTCRTNVWDARVNNPLTGFDTYKTQEFKPEQVDDFIQQWFAEAKNIKRGQELQKKLQEPQKERIRQLVKNPLRLSLLCQIFSQNKQVELPETKAELYQHFVRYFYEWKPSQSVIDWATQPGLQEELHQALGRLSIAGLDSHTRFRLPLSLIKQEMGDKLFKLALDLGWLNLVDWEATKHEPVYAFFHPTFQEYFASLVIDNYQFFMERYRIFENQWLEPAILWLENSRILAVLKKELIDTITNLKEDKWKNMYRLKLLPLNIVYSCQSGQIEFIAESVYCVCLDDNNTPTKIIYKLMFPGYEEFIIESLKYYAPKEVCDMISEVVINNTDLELDELSLSRLLEVLFKINPEHECLKVLIPKLLKDDNEGRAIEVAKIALKNDNFKQIAVDFLLNALFNEDEQYERQSFDIVNILMDSKIFDKVVIGKLTSFLNSQDSMIQSLAISNLDKISLNHNALVNNREVLDALIDFISQNRDNPISIIPAIDIVKRLDIDISKVNKAIIDLLYTSQYPVLIMSLFDYLDTQGFIVEIINKLIQLIANEEDRYESIAYAQMLVMASLSYPKFFENPSIIKKLICLVKVKVDYDYVLVQIFSQTTTMYERFKIVGYQTSKDKTFIDFISLLIEKYLNKNTTEELNSTTSNDTENIECFLIERQIERQYVEFVSLISDAEKLNFTNLMQNHFTGKLYIGDEIAIAKIKQTNFEVIDKIIEIIQTNKDNILRHICIEILIKIETLSEQSIIDKLVNLIVNLKDSQIQWFVAAVLKKITHKAQLQRLVFGLKDYVEDAVAKSDYNLHIIAYSVLWHCANNLSYTEFYDACCFQPSCTDLEALENISIANSSTAQHLKLVGQLSVIQSAVSHNEELDRAVQLIRINGSEFNPQDNPATDIYIQMVEQGCPERQEGTPTTMPLLKAYWRLNLRNLEKRVALVFYNSKIDREFSEPFLTALSAFGGTIAIITDRPCDNVKRISPNHPNLIDAVLKWLHRSILEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXU9</accession>
    <name>A0A2G4EXU9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">fabF</name>
        <name evidence="14" type="ORF">CP500_016625</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54349">
        <property type="protein sequence ID" value="PHX54349"/>
        <property type="gene ID" value="CP500_016625"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="9"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX54349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="417" mass="43961" checksum="CEB82796C74A2758" modified="2018-01-31" version="1">MTNLERKRVVITGLGAITPIGNTLSEYWDGLLAGKNGIGPITLFDPSRHDCRIAAEVKGYDPHDYLERKEAKRMDRFAQFGVSASKQALADAKFEINDLNAEQVGVILGTGIGGLKVLEDQQEIYLNRGPSRCSPFMIPMMIANMAAGLTAIQTGAKGPNSCTVTACAAGSNAVGDAFRLVQGGYAQAMICGGTEAAVTPLCVAGFAAARALSTRNDDPIHACRPFDRDRDGFVVGEGSGILILEEMEYAIARGARIYAEIVGYGLTCDAYHMTSPVPGGNGASRAMALALKDGGLTPDMVSYINAHGTSTLPNDSTETKAIKKTLGDHAYKVAISSTKSMTGHLLGGSGGIEAVAAVMAIAKDKIPPTINLENPDPECDLDYVPHTSRDLKVDVALSNSFGFGGHNVTLAFKKFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXV8</accession>
    <name>A0A2G4EXV8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54374">
        <property type="protein sequence ID" value="PHX54374"/>
        <property type="gene ID" value="CP500_016430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033072">
        <property type="term" value="P:vancomycin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="1">
        <location>
            <begin position="3"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="423" mass="45732" checksum="0F50604FDA178BCA" modified="2018-01-31" version="1">MRIMIIATGSRGDVQPYVALGKGLKAAGHSVRLVTNEDFESLVNSHELEFYPLKGNVQAFLEDPETRKLLESGKFLAINARSAKMLQSVAIAWAEGGLVAAQGMDLLVAGVGGLFLGVSLAQKLKIPLLQAYIFPFTPTKAFPAVLFPQSIAKLGGTVNRLSHHLFRQIMWQGSRKADGLARQQVLDLPTAPFWGDYNSVHLQRCPILYGLSPSVIPKPSDWRNTHVTGYWFLDKAADWSPPRALLEFLDSGSPPVFIGFGSMTSRNPEETADLVLQAIALTGQRAILQSGWGGLSKRDLPDTVFMVDSIPHTWLFPRVAAVVHHGGAGTTAAGLRAGIPSIVIPFFGDQPFWGQRVAELGVGTSPIPRKDLTAERLAKAIQQAMNDPVMRQRAADLGAKIQAEDGVANAVATVLELEKSGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXW0</accession>
    <name>A0A2G4EXW0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54375">
        <property type="protein sequence ID" value="PHX54375"/>
        <property type="gene ID" value="CP500_016435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041669">
        <property type="entry name" value="TetR_C_15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17918">
        <property type="entry name" value="TetR_C_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="212" mass="24055" checksum="D12E63266A5069A0" modified="2018-01-31" version="1">MPSKPPATPRKRPKQERSQATVQAILTATTHILTEDGYNQLTTNRVAERAGVSIGSLYQYFPNKEALIFALAEHHANEMMQLAQHHLEGLGVGEASLQENPSILEVLRQIIKAALAVHAINPKLHRVLHEQIPHSEVIRRLDEATMEKMLRSFLAQRRDQLQPKNLDLTAFIIERTIRSLIHGVMIDRPELLKTGELEQELMAMLTAYLVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY12</accession>
    <name>A0A2G4EY12_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl hydrolase family 57</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54423">
        <property type="protein sequence ID" value="PHX54423"/>
        <property type="gene ID" value="CP500_016195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="498" mass="55909" checksum="D00C7890ECA2C19B" modified="2018-01-31" version="1">MPAIAQSPNLLILNEINSGLPNICGSEAEISAAVNSNEPVFLPTTNLRLENIQAGFACALHMHQPTIPGGANGELICNLQHMFEHPNQGDNHNAGVFAWCYSRMGEFIPQLIAEGCNPRIMLDYSGNLLWGLRQMGRDDIFDNLKRITSDPQYQPHVEWLGTMWSHAVIPSTPIPDIKLQIQAWQHHFASIFGIDALKRVKGFSPPEMHFPNHPDTLYEYIKALKECGYRWLMVQEHSVENLDGSGLSQDQKYIPNRLMARNSHGETISITALIKTQGSDTKLVGQMQPYYEAKGRNKQQIGKVTIPSLVTQIADGENGGVMMNEFPSAFMKAWHENREQGGGKSGVVGLNGTEYLELIEAAGVNPDDYPICQGINQHKIWQLVDADSATPEKVESAIVQIKQTDHNFHMDGASWTNDLSWVKGYENVLEPMNQLSAAFHQKYDTLVQEDATVTKQFEYQQALLYNLLLQTSCFRYWGQGTWTDYARELYNRGAALMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY20</accession>
    <name>A0A2G4EY20_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="1">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">coaE</name>
        <name evidence="2" type="ORF">CP500_016115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3'-dephospho-CoA + ATP = ADP + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000101">
        <property type="protein sequence ID" value="PHX54435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54435">
        <property type="protein sequence ID" value="PHX54435"/>
        <property type="gene ID" value="CP500_016115"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00152">
        <property type="entry name" value="TIGR00152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="205" mass="22912" checksum="DCD8EAD9449D62F9" modified="2018-01-31" version="1">MSDRIVRLIGLTGGIATGKTAISNYLADTYKFPILDADIYAREAVHPGTPILNSIRERYGASILLSDGNLNRPELGNIIFCNPTERQWLEQQIHPYVRHRLVEATQSYIAQLSLVSTNTLTLVLVVPLLFEANMTDLCTEIWVVYCSPSVQLERLMHRDGLSCDRANARIDTQLPLNQKCQKADVVLDNSSTLQSLLSQVDSKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY59</accession>
    <name>A0A2G4EY59_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54475">
        <property type="protein sequence ID" value="PHX54475"/>
        <property type="gene ID" value="CP500_015940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="12381" checksum="FEDACC0750DDB421" modified="2018-01-31" version="1">MKYFFLSDGWAIARVWGVGGLWTDAGWRRQPDIKQLNVCLWDQKEKMWLYRVEDAVLMVEVKPTAPADNTDPAKNIGSVVLTRLIDAEQVIDRLGAIAAHCQIENPQPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY78</accession>
    <name>A0A2G4EY78_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54471">
        <property type="protein sequence ID" value="PHX54471"/>
        <property type="gene ID" value="CP500_015920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="7714" checksum="69F6D67EC0485ACF" modified="2018-01-31" version="1">MLQEFGLNLKRPHVDTLNGWLDDISDNFAAIFGRSEGCSFTFVDGGDNGNRSIVLGDGEGFAIYPTSILSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYG8</accession>
    <name>A0A2G4EYG8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54536">
        <property type="protein sequence ID" value="PHX54536"/>
        <property type="gene ID" value="CP500_015560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15866" checksum="5C5643194801F4AB" modified="2018-01-31" version="1">MVRFQELQVYQLAEQISNEVWFIVQSWDLFAKNTVGKQLVRSVDSIGANIAEGNGRYNYNDNQRFIKIARGSLHETRHWLRLACARHLLTTEQIDRIKPLIDELSPKLNAYLNSIQSKATTQALKIKKTPKSQPPTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYI4</accession>
    <name>A0A2G4EYI4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">trxA</name>
        <name evidence="6" type="ORF">CP500_015495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54556">
        <property type="protein sequence ID" value="PHX54556"/>
        <property type="gene ID" value="CP500_015495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="11915" checksum="C4EE62BF83EB3FE4" modified="2018-01-31" version="1">MAVQKQFSSFEELLSGSDLPVLVDFYATWCGPCQIMVPILEKVSSQTKEKLMVVKIDTDKYDQLASQYHIYALPTLVLFKNGAEVHRIEGVIQPAQLIDRLQPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYJ4</accession>
    <name>A0A2G4EYJ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LPS export ABC transporter periplasmic protein LptC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lptC</name>
        <name evidence="7" type="ORF">CP500_015110</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54605">
        <property type="protein sequence ID" value="PHX54605"/>
        <property type="gene ID" value="CP500_015110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015221">
        <property type="term" value="F:lipopolysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010664">
        <property type="entry name" value="LipoPS_assembly_LptC-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026265">
        <property type="entry name" value="LptC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06835">
        <property type="entry name" value="LptC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04409">
        <property type="entry name" value="LptC_YrbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013606033" evidence="6">
        <location>
            <begin position="33"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="398" mass="44151" checksum="C42ADBBF218FD873" modified="2018-01-31" version="1">MINLKSKTSNFSFPKALLLTLVALLLGMGGCAAPSDTQKNKLAEDLKTAEKSNSTLTLNKVILEQANEKGELFWKVKSKDAVYSKDNKIVNVQKPVGKLFQDGKEIYDIQAETGEVFQEGNQIFLKGKIVATDLKNGVVLKGNELEWRPKQDVLVVRNNLTGDNKQMNASAKEARVFTRARRMELFGSVVADIKDPVLQLRTEHLIWFLDQQKVSSDKPSQLDRYKDQKVTDRGFADQTDVDLKTKIATLTKNAQLMPSDPPLQIDSSLMSWNFPAQSVVSPGPVKVFHRVEKVTMTGDTGRGDLDKKIFYMTGNVLGIGQKRQSQLNSDRVIWYLANQTFDAEGNVVYRQLDPVFNLTGPKASGQLKDQTVIVKGDGGGGQVVTEFVPDEKNATLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYR4</accession>
    <name>A0A2G4EYR4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cyanoexosortase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">crtA</name>
        <name evidence="10" type="ORF">CP500_014725</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54675">
        <property type="protein sequence ID" value="PHX54675"/>
        <property type="gene ID" value="CP500_014725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026392">
        <property type="entry name" value="Exo/Archaeosortase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019127">
        <property type="entry name" value="Exosortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022505">
        <property type="entry name" value="Exosortase_cyanobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09721">
        <property type="entry name" value="Exosortase_EpsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03763">
        <property type="entry name" value="cyanoexo_CrtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04178">
        <property type="entry name" value="exo_archaeo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="282" mass="31065" checksum="DDC8398F8CFC53F1" modified="2018-01-31" version="1">MTEIKWLNHLQEPKYWLLGIASGLILLQLTLTSRTDNADLFGTMFLFWGVVCFLISEKHETLTLESGVFGTCFGASLISFILLKSSSISGYDFFIRVMPFLSGISLALLASGTKGLKQYWQEFLILGYTAIPPGFIGVFVDVAKLTAKFSAFILHYVGFEVVRQGAFLILEKGSVEVNHGCSGVNAILQLLGLALVFLLMFPTTVGQKIVVPIVALLIGFVVNSARVALLAVLVSLSQPQSFKYWHEGNGSVIFSMIAVFIFGLFCWFGILQEPQNKKKQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYV1</accession>
    <name>A0A2G4EYV1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-alanyl-alanine synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54702">
        <property type="protein sequence ID" value="PHX54702"/>
        <property type="gene ID" value="CP500_014690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="4">
        <location>
            <begin position="143"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="391" mass="43879" checksum="B70DE3665B2DD9BD" modified="2018-01-31" version="1">MIATSIGMNSCDYDFSLLPEYLKVLQTKLRIAVVFGGNCDQAGSVIYKTHNPRSWKSYEIVAREIAQALTEIGFKQVFVMPDDMNLPGKLKAENIHLVWMNTGGVQGYNPVCHTPALLEMLGMPYIGHNPLNSSTLDNKHAFKRELQSVGIKTAPFMTWHPSQGILRPNLHERFAIAFREYQGPFIVKPVSGRASLHVHFVETMEGLSEAVSEVHRATHNTALIEKYLPGREFCVAVCGYVTYAQGCFDKNPKPFAFSTIERVLESDEQIFTSMDQKAITADRGKLIGTEEPGLKQELIELAQKIYWEFSLNSLVRIDVRSDANGELYVLEANPKPDLKRPAENLTSLVALGLAEYGMSYNDLIFSLIADRLDYLLTQNMGIIPHIVELLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYW4</accession>
    <name>A0A2G4EYW4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000082">
        <property type="protein sequence ID" value="PHX54713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54713">
        <property type="protein sequence ID" value="PHX54713"/>
        <property type="gene ID" value="CP500_014615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1014" mass="116837" checksum="200ACA56CC662CE3" modified="2018-01-31" version="1">MNILRLDNSDLVPVDYGDLLDKILEVLRGKNPFSVSGDRRRLIVDIDAIAADVAKIEVRKPLGSFERQADCATVNFPQEVEEHFGDRIKQIKECLRQNLESKLPQNASIEKFVTSLITPLSSPSFRGNGQELGFKYDFGKRHPSLEKEKLTLHPLDSGSHATLKLHKLTIAVRNTDIFQQQLKEGLENYINEKADTNDDRQELHHRLDEMVKNQDSDFYKLIRLVDKETLGKLNKEAKITYLEYLLEHIQGSSTDTVGIIYLEDLIRRLRLLEKYINDSNKADGEYEVNYAGFRFNYREIFARAEVLDALPIIPIVAGYLGESTDTPQSERKFIFGLKIKFNNPVQARGGKEAFEYYLNLLNPDSEEHQAAIGEDSIDSITETFARKVLRIALLYYFVFASRHDPLAQNYDAEAELNHHPIAIFEQRVLPVLQGSDDEAKRELFRNFIEGFKKFNIKHKISHLKKMLKGFLERQTILPSRTETRHVNLKMGLLEDIDNILTNCKFFNDIMERNYKQTLHYIAVEPATLSETAICQLPVNITIEDVRYFPTDERQTFSMEYNVEGVDVLPILSAPKAQRSRDIYKYHFNTKLVLFPYDDRRLDSGEKGLQPAAAFVYKFTMLLLSYICMRILLENKAENLFIPMARLHEGVHKHPSPSEEFMANVSKTLSHILSEKHRSTSQGFRIRERVDGFHVRNGLSSMYSILPKKFRFDNVQLSPELDKLAIIVVSSRDSDAKKGNQNRFQRQASLIGEVIGINQLNDSTIQVEMLKTFSENYSVSRLYTEPVILEDVMSQLYQQGYRNFAYISQAPYMSKLHITKTEEDEEMSFMSRKLLRTLKGERRDIKIYPMFFDKYFVRSFLGDKSKSFYIQDAMELESLSAKGNQQAVMFFNLFNGINVKQPGGKNFYNGVISYSTLLHIYDGILDDQDLHQGLIYDGEIKDTLLHYLTIFHFSRYEARHNISLKLDPYERIIGDDSVGALSMFRHAGGNAEFNSLAFLNKVREVLNVGDGGTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ61</accession>
    <name>A0A2G4EZ61_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54799">
        <property type="protein sequence ID" value="PHX54799"/>
        <property type="gene ID" value="CP500_014115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="315" mass="34936" checksum="10B1EAE129FD532E" modified="2018-01-31" version="1">MSDLPFTLDQLRILKAIASEGSFKRAADSLYVSQPAVSLQVQNLERQLDVPLFDRGGRRAQLTEAGHLLLSYGEKILSLCQETCRALEDLQNLQGGTLIVGASQTTGTYLLPRMIGMFRQKYPDVAVQLHVHSTRRTAWSVANGQIDLAIVGGEIPTELLEALDVVPYATDELALILPPSHPMVQQETIQKEDLYKLQFISLDSQSTIRKVIDQVLSRCGIDTRRLKIEMELNSIEAIKNAVQSGLGAAFVSVSAIEKELLMGVLHKSQMEEVVVTRVLSLICNPNRYRSKAAEAFSNEILPQFATYTAIKEKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ79</accession>
    <name>A0A2G4EZ79_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_014060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54788">
        <property type="protein sequence ID" value="PHX54788"/>
        <property type="gene ID" value="CP500_014060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="6">
        <location>
            <begin position="167"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="7">
        <location>
            <begin position="294"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="198"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="370"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="212"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="401" mass="46117" checksum="23E49C96BE9E3572" modified="2018-01-31" version="1">MLVFEAKLEGKSEQYERLDEAIRTARFIRNSCIRYWMDTPGVGRYDLSAYCVVLAKEFPWASKLNSMARQASAERAGSAIARFFDNCKKAKPGKKGFPRFKKHETHGSVEYKTCGWKLSEDRRNITFTDGFKAGIFKLWGTRDLHFYQLSQVKRVRVVRRADGYYVQFCIDAERNEKREPTGKTIGLDVGLTHFYTDSDGNTVENPRHLRKSERSLKKLNRRLSRTQKGSKNRAKARNRLSRKHLKVSRRRKDFAVKLARCVVQSNDLVAHEDLQVRNMVKNKKLSKSISDAAWTAFRNWIEYFGKVFGVATVAVPPHYTSQNCSSCGKVAKKSLSQRTHICPHCGFVLDRDWNAARNILELGLRTVGHTETSNASGDIDKSLNEETLLNKSDRRKRKPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZA5</accession>
    <name>A0A2G4EZA5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54841">
        <property type="protein sequence ID" value="PHX54841"/>
        <property type="gene ID" value="CP500_014025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="155"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="373"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="53107" checksum="1BDE2124434977B7" modified="2018-01-31" version="1">MDVKELSKWTDEQVFAKTGQHLDSLHKSILESVLQRQSFHKIAGNNGYSYDHVKKEGAKLWKLLSAVFSEEIEQKNVRSILENQAGSTIYSFGNSSLIISNHNINKNHVNICRENPQSLEDIEKRSPSSQVQNQLPIIYLTTAPELNYNYGRNSEIHTLKEWILEDKTRLITIYGLSGIGKTALTLKLISEINTQFDYIIYRSLEHLPKLIDLKDELKQFFSQSHATPLPEIIDYFRSSRCLVILDDVQNIFKTGNFAGQYLTDYKDYCKFFQQIATLSHQSCLILISWEKPGEIETLEKENKHTRVLQIQGLGEEAKEILRQKDLQDEEKWEKLITLYQSHPAWLNIICSTIIEFLNGSVSLFLTDENELFLGDIETNLESQLERLSELEKNVINWLANQDEPIDISQKPANMEVSQAKFMHILQSLTRRCLVEKVPRKEPAKFQLNSIFKAHIKSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZE1</accession>
    <name>A0A2G4EZE1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54879">
        <property type="protein sequence ID" value="PHX54879"/>
        <property type="gene ID" value="CP500_013665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014056">
        <property type="entry name" value="Addiction_killer_pred"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41791">
        <property type="entry name" value="PTHR41791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028744">
        <property type="entry name" value="Addict_mod_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02683">
        <property type="entry name" value="upstrm_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="13086" checksum="0ADAF01FF70D5276" modified="2018-01-31" version="1">MEVQPRDIQRYVKSDGQIPFDEWFYALRDSQAKLKINVRLKRVSTGNFGDYRPVGEGVWELKINFGPGYRVYFGQVETTIVLLLCGGDKSTQDEDIRKAKKYWIKYRSQDNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZH3</accession>
    <name>A0A2G4EZH3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54587">
        <property type="protein sequence ID" value="PHX54587"/>
        <property type="gene ID" value="CP500_015220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="470"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="536" mass="58685" checksum="52DB284243BDCD0B" modified="2018-01-31" version="1">MTLKRIFLGILTAIAIALVGLSLLASWNEPQIQSRLELYQTNLLLHASEWQGENNSSSNSSSNLTSARNSIVGTNPLDAALAQYADARTSTQKTLATTQTQLKELQSSSISNPQDTAQNVKLAQSNALEESIHKLSTLKSELDLRVGILQASANKTNVALKTWQDLIEPNNTLINSDTSIKTAQVLNGIWSNPAQLLPDAESSIKKSLDGWFRYRALTQLYKLEERDKELASLQSAEQVIAAQSVEKLAIVIGIPGIGLCIGTVLLVGLTVQWFLQRKQLDTAGSVPILARNGSLTWDVPWDGEIVWQVLVVGFFFVGQILIPYLLLPVSLAVLKFNPASFDPRSKAFYIFTTYLFLSAGGLSVLYFSVKSFLPLPESWFRINWRGNWFWWGFGGYFVALPLVVLVSLINQQFWQGQGGSNPILPIVLEGKDNVALAVFFATAAIAAPVFEEIMFRGFLLPSLTRYLPVWGAIATSALLFAVAHLSVSEILPLATLGAVLGFVYTRSRNLLAPMLLHSLWNSGTLLSLFLLGSGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZI9</accession>
    <name>A0A2G4EZI9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3285 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54908">
        <property type="protein sequence ID" value="PHX54908"/>
        <property type="gene ID" value="CP500_013550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021702">
        <property type="entry name" value="DUF3285"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11688">
        <property type="entry name" value="DUF3285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="7738" checksum="9B76612A16E86915" modified="2018-01-31" version="1">MSQPPSAPTTSEEPAETPTQPASTAPQPSYVKLAMRNMVRKRGTSLFHFALTAAALLGVLVGLAFLDRYFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZJ2</accession>
    <name>A0A2G4EZJ2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_013510</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245953">
        <property type="entry name" value="M.Tbo703ORF13510P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54931">
        <property type="protein sequence ID" value="PHX54931"/>
        <property type="gene ID" value="CP500_013510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004546">
        <property type="entry name" value="Restrct_endonuc_T1M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00497">
        <property type="entry name" value="hsdM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HsdM_N" evidence="4">
        <location>
            <begin position="15"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="3">
        <location>
            <begin position="198"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="540" mass="61535" checksum="B9239E4B9872E069" modified="2018-01-31" version="1">MTNGQNGQNGQKKKLETQLWNIADSLRGKMNADEFRDYCLGFIFYKYLSERQYLYANAILAEDKIDFLELDESSAEGQEYLEAIQEESIAQLGYFLKPSELFGALAKRALGNKAEEEEISDEELEASSIFILDDLTQVLNSIERSTMGKESEEDFDHLFEDLDLTSTKLGRTPKAKNALIAKILVHLNKIDFRLEDSESDVLGDAYEYLIGQFASGAGKKAGEFYTPQQVSKVLAKIVTTGKRRLLSVYDPTCGSGSLLLRVAREVDKVEDYYGQEMNRTTYNLARMNMILHGVHYRNFDLRQEDTLEKPQHEGMRFEAVVANPPFSAHWSANKLFESDDRFSQYGRLAPSSKADFAFVQHMLHHLDENGTMAVVLPHGVLFRGAAEGEIRKYLIDERNWLDAVIGLPANIFYGTSIPTCVLVFKKCREHPEDILFIDASANFEKAKNQNFLRDDDVDKIVATYRDRLQEDKYSYCAPLSEIAENDFNLNIPRYVDTFEEEEEIDLGAIALELRSMDRAMEESDRLIRGFCDELGIDVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F018</accession>
    <name>A0A2G4F018_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Long-chain fatty acid--CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55103">
        <property type="protein sequence ID" value="PHX55103"/>
        <property type="gene ID" value="CP500_012575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="41"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="649" mass="72493" checksum="00FB28D17679A3C4" modified="2018-01-31" version="1">MNRSASYTSSQMTDRDRANLSRLIDYSSIQSVPEIWAIVQQKFGQTIALHDPHSKPEIKLTYTDLYQQIQQFAAGLQALGIEPNPGEAIPPRVALFADNSPRWLIADQGIMMAGAANAVRGATADPEELLYIIKNSGCTALVVENRALLKKLQHSLPDLPIQLIVLLSDEEPEASQTLNTVKFSQVMATGANRALKPSNHKPQGLATLLYTSGTTGKPKGVMLTHGNLLHQITTFGTILQPEAGEGVLSILPSWHAYERTVEYFMLSQGCTQIYTNIRYFKQDFKTYKPQYMVSVPRIWESIYEAVQKQFREQPANKQKLVNFLLSASQQYIEARRIFQGLTLNLKPASASEKLIARIKSILLWPVHAVAEKLVYQKVREATGGRFKWAISGGGSLATHLDNFFEIANIGLLVGYGLTETSPVLTVRRPWHNLKGSAGQPIPHTEVKIVDPDSRQQLSIGQRGLVLARGPQIMAGYYLNPEATSKAIDPEGWFDTGDLGWLTPGNDLILTGRAKDTIVLTNGENIEPQPIEDACIRSVYIDQIMLVGQDQKSVGALIVANVEAVQKWAETQNPPIHEIDWNSKTIQDLFRQELNREVQNRPGYRTDDRIGPFRLILEPFSMENGMLTQTLKIKRPVVTEHYRDMIDGMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F058</accession>
    <name>A0A2G4F058_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55135">
        <property type="protein sequence ID" value="PHX55135"/>
        <property type="gene ID" value="CP500_012180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="269"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="333" mass="37708" checksum="D14CA6EF71CDE679" modified="2018-01-31" version="1">MKFINPKTDYAFKKIFGSDQSQDILISFLNAIVYQGETFITSLEIIDPYAPGRISGLKTTYFDVKALLNNGENVLIEMQAFNVPAFGKRILYNTAKMYVNQLKLGEVYPELRAAIGVAVTDFIMFDEHSKVISQFILKEDELLLNYQHSPLKLVFVELPKFNKTLEELTNVTDKWLYFLRRAPDLEVVPASMSIVPEIEKAFTIADRVNLSLEEVDDLEKREQFERERVGALELSKAEGLAEGRVEGLAEGIQIGEQIGIQIGEQRGEQRGEQRGKINLIKRLLQRQLGELNQEIEARLSQLSSEQLSALAEAIFDLSNVADLSSWLETNCPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0A7</accession>
    <name>A0A2G4F0A7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55202">
        <property type="protein sequence ID" value="PHX55202"/>
        <property type="gene ID" value="CP500_011930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010004">
        <property type="entry name" value="Uncharacterised_Ycf66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07444">
        <property type="entry name" value="Ycf66_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="269" mass="30717" checksum="2FC44238D1B33D73" modified="2018-01-31" version="1">MVNLGLNWSSLLGIILAVAGAGLYFLRSWRPKLARDHDIFFAAVGLLCGGILLFQGWRLDPILAFGQFMLTGSAIFFAAESIKLRGATTAQAKSRAQYVDEERPVSNAYGYDNNYDSEIDRLEPEEDYPQRPRIRGSQDNRSSRESYDDEPRRRPSNRNSSIDTSKPESPERSRKRPSRPETPPPERSDNWDFSDNPEERPTRSRNNRPPASENRNSDTPPRTKKKRPTEASRSRPSSRDMETPTSDYVEYRPVESPEDQPDDSTNFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0C6</accession>
    <name>A0A2G4F0C6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Galactosyl-1-phosphate transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_011950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55206">
        <property type="protein sequence ID" value="PHX55206"/>
        <property type="gene ID" value="CP500_011950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="3">
        <location>
            <begin position="44"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="243" mass="28321" checksum="F122F54989EC163E" modified="2018-01-31" version="1">MTADSQLISGKVIRAIARRGFQPVFSRDRRMSRSLQNLDGEFFKRLFDIMFSLSVLILFAPVYLLLAFSIALSSSGPIFYVQKRVGKNHKMFYCLKFRTMVENADDILVEIMQKSPHLRQEFEDNFKLKQDPRITCIGRFLRATSLDEFPQFWNVLKGDMSVVGPRPLVEEELPRYGSYINKILTIRPGITGLWQVSGRNDIPYPRRVQIDLYYANEKNLWMDMWIVFKTIGVVIFPKNNGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0T5</accession>
    <name>A0A2G4F0T5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1 2">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name evidence="4" type="ORF">CP500_011275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PTH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1 2"/>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55372">
        <property type="protein sequence ID" value="PHX55372"/>
        <property type="gene ID" value="CP500_011275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01195">
        <property type="entry name" value="PEPT_TRNA_HYDROL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="220" mass="24482" checksum="4C418D301397304A" modified="2018-01-31" version="1">MNKTQNSETPPELVIPQLIVGLGNPEPKYDRTRHNIGFNAVDALAQSWQISLSENRKFQGIFGEGNRPRGQKIRLLKPLTYMNLSGQAIRAATDWYKIPPQSVLVVYDDMDLPIGKIRMRLSGSAGGHNGMKSTISHLGTDKFPRLRIGIGKPQDDPSKNEKDTISFVLGKFSLDESQLLEKVLKLVREAVELSLHQGVEKSMSLYNNRTIAVTNAETKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0X4</accession>
    <name>A0A2G4F0X4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4332 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_011095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55409">
        <property type="protein sequence ID" value="PHX55409"/>
        <property type="gene ID" value="CP500_011095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025567">
        <property type="entry name" value="DUF4332"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14229">
        <property type="entry name" value="DUF4332"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4332" evidence="3">
        <location>
            <begin position="23"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="16188" checksum="50042A3D179CAE82" modified="2018-01-31" version="1">MPTYHKTHGSSVQARDWPIANLPGLSNDNQSQLATCGISTIAQLICQTKTPTAKISLAHQLQVDIRYVNKWVAMANLARIPSVGCEYCGLLLHAGVASPAQLAQIPVGRLHQQILRLHVATMQRNDLTPSVDRVQKWIQDAKLVISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Y0</accession>
    <name>A0A2G4F0Y0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA topoisomerase 1</fullName>
            <ecNumber evidence="8">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">topA</name>
        <name evidence="11" type="ORF">CP500_011070</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55405">
        <property type="protein sequence ID" value="PHX55405"/>
        <property type="gene ID" value="CP500_011070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025589">
        <property type="entry name" value="Toprim_C_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13368">
        <property type="entry name" value="Toprim_C_rpt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="10">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="8">
        <location>
            <begin position="175"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="877"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="892"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="911"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="952" mass="104211" checksum="2E394BFF34C52375" modified="2018-01-31" version="1">MSTLVIVESPTKARTIRNFLPSTYRVEASMGHVRDLPSSAEEIPEAVKGEKWAQLGVNVEADFEPLYVIPKDKKKIVKELKDALKDATELILATDEDREGESISWHLLQILKPKVPIKRMVFHEITREAIRDALTHCRDIDNRVVQAQETRRILDRLVGYTLSPLLWKKIAWGLSAGRVQSVAVRLLVRRERERRAFRQGSYWDLKATLTPPNPPLGKGGASDNTPLGKGGASDNTPLGKGGQGGAFEAKLVTVGNVKVANGSDFDENTGGIIAGRRVLLLNEEQARALLERIQNKPWTVTNLEERPVTRKPSPPFTTSTLQQEANRKLRLGARETMRIAQSLYERGFITYMRTDSVHLSEQAIAAARSCVQELYGSEYLSPKPRKYTTKSKGAQEAHEAIRPAGSTFRTPQQTGLDGVDFRLYDLIWKRTVASQMADARQTHVTLLTLVEDAGFRSSGKRIDFPGFLRAYVEGSDDPDAALEDQEVILPALKVGDKPNCKDLEAVGHETQPPARFTEASLVKMLESEGVGRPSTYASIIGTIVDRGYAKLVANALIPTFTAFAVTTLLETHFPDLVDTGFTSRMEQTLDEIATGEAKWLPYLDKFYRGETGLQTQVKEQESQIDAKVARTVVLENISAKVCIGKYGAYLEAEREEGPVKASIPQDLTPADLDPEQVEFLLKQKTEGPEQLGLHPETGEPIFVLIGSYGPYVQLGEITETNKKPKRSSLPKGTDKDTMTLEMAVSLLTLPRLLGTHPDTGAKVQAALGMYGPYVVHDQGKVGKDYRSIKVPDDVLTITLDRALELLAQPKAVRGSSKTATPLKELGAHPESGELLNVYDGRYGPYVKHGDINASLAKDESVENFTLQKALDLLAAKEAAGGGKSSKSKKSTKTTAAKSETAEKKTTTAKKTTAAKSETAAKKTTAAKSETAAKKTTAAKKATTATASKKKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F123</accession>
    <name>A0A2G4F123_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidoglycan lytic exotransglycosylase</fullName>
            <ecNumber evidence="2">4.2.2.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Murein hydrolase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_010795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exolytic cleavage of the (1-&gt;4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.</text>
            <dbReference type="EC" id="4.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.n1" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55459">
        <property type="protein sequence ID" value="PHX55459"/>
        <property type="gene ID" value="CP500_010795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14485">
        <property type="entry name" value="mltA_like_LT_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010611">
        <property type="entry name" value="3D_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026044">
        <property type="entry name" value="MltA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034654">
        <property type="entry name" value="MltA_3D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005300">
        <property type="entry name" value="MltA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30124">
        <property type="entry name" value="PTHR30124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06725">
        <property type="entry name" value="3D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03562">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019422">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00925">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="SSF50685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MltA" evidence="6">
        <location>
            <begin position="164"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="407" mass="44468" checksum="96CF89189CA9747A" modified="2018-01-31" version="1">MSKGYQKLGMGNWLRGKIFRYQLLTIAFCVLAIAFAVPVVAVPPLQTMSLTQLSASESESIAFDAQIWGENGQPGDKALLLKSIDYSLGYLSTAASANAYSRYQVAGITRDRVRRSLDRFRQLVINSTTPAQLQQSVKQEFVFYKSIGKDSKGTVAFTGYFEPTYAASRSPTAEYRYPLYRVPPNIASWPKPHPTRLELEGADALQASKGLLRGLELVWLRDRFQAFLVHVQGSARLQLTDGGVMTVGFAGKTSHSYTGVGRELVKDGKFTLEQLNLPKLTEYFANSPAEMNKYLPKNQSFVFFRDTNGVPATGSIGVPVTAERSIATDKSLMPPGALALISTKLPYPNAAGKLEQNAVNRYVLDQDTGGAIKGAGRVDVFMGTGNLAGDRAGFINSTGELYYPLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F150</accession>
    <name>A0A2G4F150_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55482">
        <property type="protein sequence ID" value="PHX55482"/>
        <property type="gene ID" value="CP500_010695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="713" mass="80818" checksum="1FA6B5B99E7756D2" modified="2018-01-31" version="1">MNLTENKLYSKIAINGTLLLLVFFITIAVSSIYVSSEHTFYWWDYAGYNNATVGLANSFRESPEKAVRAVIESLANEKNLLISLPLVPFILLFGDSRLSYILSVSLIYVVPFRLLLGAISVKLIPVYPRRVFWSTVLLSFLIPMSWIPTLRGYLDTGGCVFVALAILVYLHDVKLKYWWQILLIGFSLAMAILFRRHFAYSAIAFFGAAILQYLIEFILTYKNLKNQAWKNLFTSGMKLGLIMATSFAILMLVAGDFTRSALTVDYRNLYMAWSLPVNDILTRYANFYGLGTWLLVMIGFSAGLVTRILLPSTTIFIAIFGILSLIEWLLVLRYGYLHYTIHITPIALLGLSAFFWTTWLTRPGKVRYLMLGVAGLYLSVNAVLGLIPLKLDISRLFMGNFPPLVRSDYGEVVKLVEFLRKIAPNQEPIYIAGASNSFNANILKQANRKLNPPEGWWKLNTLGRPLIDSRDTYPLPELLISQYVVVATPFQQVLLSDEQVLRSHEQDVVKVVYDAFTQNWEISRDFQLLPEQFQLENGVIVRVYRRMRPSAIGTAIKTLNVMQQQIAEKPGTQLDWISLNQSVYTSSNYPVKKESDYLYNIVTHPIKNTKQLDTSFLYLGSLSEKKQISGKLNLPNKQCEGVSLRLTLWNNQGKLINSTETAYNLTASPKLNLLLEGKSPNYLLLEVLSTNKQDLTNQCQLEINNLAISAPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F168</accession>
    <name>A0A2G4F168_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">GDP-mannose 4,6-dehydratase</fullName>
            <ecNumber evidence="3 4">4.2.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GDP-D-mannose dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">gmd</name>
        <name evidence="6" type="ORF">CP500_011955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H2O</text>
            <dbReference type="Rhea" id="RHEA:23820"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="EC" id="4.2.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="3 4"/>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55207">
        <property type="protein sequence ID" value="PHX55207"/>
        <property type="gene ID" value="CP500_011955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019673">
        <property type="term" value="P:GDP-mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="PTHR43715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01472">
        <property type="entry name" value="gmd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="5">
        <location>
            <begin position="8"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="343" mass="39546" checksum="524967B8CAE90D1B" modified="2018-01-31" version="1">MTQRKRALITGITGQDGSYLSELLLEKGYEVHGIIRRSSSFNTDRIDHIYVDPHSDDAKLFLHYGDLTDGTTLRRILEEVQPVEVYNLGAQSHVRVSFDSPEYTVDAVGMGVLRLLEAVRDYQRRTGIEVRFYQAGSSEMFGLVQEVPQKETTPFYPRSPYACAKVYGHWQTINYRESYGLFACNGILFNHESPRRGETFVTRKITRALARILVGKQNKLYLGNLDSKRDWGYAKDYVQAMWLMLQQEKPDDYVIATNETHSIKEFLHLAFTYANLNWEDYVEFDQRYLRPAEVELLIGDSTKARTKLNWEPSVTFEQLVHLMVDADIKALDQQLRGSGNGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F184</accession>
    <name>A0A2G4F184_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secretion protein HlyD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55520">
        <property type="protein sequence ID" value="PHX55520"/>
        <property type="gene ID" value="CP500_010460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="123"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="380"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="599" mass="66449" checksum="8AB05001A1CAE49C" modified="2018-01-31" version="1">MLSEDAKELGCAPDEIDEIYGGVALKENEVSQKDRSLEVVEPQNRSSKINDYINPAKLRTHEEDNWSTSLQSVLDQPAVSFPQKLILGGMVFSVAFGAWAIFGKIDQVGHAQGKLVPKGDVYKIHPTEPGKIINIAIKEGQKVTTGQLLAELDPETASGEVERLDKILNGYQIQLVQQISSIERTRLEAQASKAIAEADKRGAQAAIDRARASVATTQSQIEQLQFDVVSQKARQQKLKPLEKQAQDLVSQLQTDINSQQGRRDRLKPLQRKTQDLLTQLQTKVAAHKERIARLKPLVDEGALSKDVLFQAEEALRESENAVIRSQLGEESQAHDRAFEVEQTVRDKQGAQIRSQLSDVTVVKEKLFEVEQGLRDRTSAISKTQGELAEQLAEVDRLQAQAQSQQATARQTQLEKEQKVQQLEMELNQVKSKIAETQTLLTQSKNKLKQRFLYAPVNGVISALNVHNIGEVVQTGQTIAEMTPNNAPLVLEVSLPNREAGFVKTGMPVQVKFDAFPYQNYGVIPGKVVSISPDAKTDERLGVFYRVQVSIDRDSVKANNQTWKLKAGQTASAEIVIRQRSIADILLDPLKQLQKGGMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F195</accession>
    <name>A0A2G4F195_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55523">
        <property type="protein sequence ID" value="PHX55523"/>
        <property type="gene ID" value="CP500_010475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7038" checksum="BECC7983132B1655" modified="2018-01-31" version="1">MTQNKVVIKRIVSPDCKVIAEAKSVVSKSTDGATQISQSVAVNISSNNSSSSYTSSSSSSTSSCFSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1A6</accession>
    <name>A0A2G4F1A6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-specific adenosine deaminase</fullName>
            <ecNumber evidence="3">3.5.4.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tadA</name>
        <name evidence="5" type="ORF">CP500_010380</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:43168"/>
            <dbReference type="Rhea" id="RHEA-COMP:10373"/>
            <dbReference type="Rhea" id="RHEA-COMP:10374"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.33" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55539">
        <property type="protein sequence ID" value="PHX55539"/>
        <property type="gene ID" value="CP500_010380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00972">
        <property type="entry name" value="tRNA_aden_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14437">
        <property type="entry name" value="MafB19-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="145" mass="15573" checksum="EEB2DC3369018803" modified="2018-01-31" version="1">MSRAVELALVAGDAGEVPVGAVIVDGGGKLIAQSQNRRERDCDPTAHAEILALRAAGQVLQDWHLNQCTLYVTLEPCPMCAGAIVQARLGLLVYGADDPKTGTIRTVGNIPDSAYSCHRLEVLGGIMESACREQLLSWFESRRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1C7</accession>
    <name>A0A2G4F1C7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycine oxidase ThiO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">thiO</name>
        <name evidence="3" type="ORF">CP500_010260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55559">
        <property type="protein sequence ID" value="PHX55559"/>
        <property type="gene ID" value="CP500_010260"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012727">
        <property type="entry name" value="Gly_oxidase_ThiO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02352">
        <property type="entry name" value="thiamin_ThiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="2">
        <location>
            <begin position="6"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="362" mass="39508" checksum="76465A645437A0F5" modified="2018-01-31" version="1">MNSSTDILIIGGGIIGLSLAVELKLRGASVAVLTVDAKQPTARAAAGMLAPQAERIPPSPMLDLCLQSRALYADWVDKLEAITGLKTGYWRSGILAPVYHVDGQEKSCLSSLNAEWLDKNTIHQHQSGLGEEVMGGWWYPDDAQVDNRALFRTLQFAIKELKIEIIQGCVTDIIRQGNRVFGIETTAGKLQANRYVLATGAWSEKLLNIPVYPRKGQMLSVCVPESYEVSQPLQTVLFGTGIYIVPRQDGRIIIGATSENVDFTPGNTAAGINSLLTGAIKLYRELQNYPMLELWWGFRPATPDELPILGASAWENLTLATGHYRNGILLAPVTAKLLADLIEKGDSDPLLAAFDYSRFGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1J7</accession>
    <name>A0A2G4F1J7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55622">
        <property type="protein sequence ID" value="PHX55622"/>
        <property type="gene ID" value="CP500_009835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="12792" checksum="FC5E5BC7E63EF9CC" modified="2018-01-31" version="1">MARLYSDEQYPIAVVRILRTLGHDVLTVQEAGNAGLKIPDDRVLEFATSDARSVLTLNRQDFIRLHRIQPNHSGIITCTNDRNWERLASRIDEAISAEETLAGKLIRVIRPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F200</accession>
    <name>A0A2G4F200_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF3641 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_008885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55794">
        <property type="protein sequence ID" value="PHX55794"/>
        <property type="gene ID" value="CP500_008885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024521">
        <property type="entry name" value="DUF3641"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026351">
        <property type="entry name" value="rSAM_SeCys"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43728">
        <property type="entry name" value="PTHR43728"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12345">
        <property type="entry name" value="DUF3641"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04167">
        <property type="entry name" value="rSAM_SeCys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="28"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3641" evidence="6">
        <location>
            <begin position="188"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="328" mass="36719" checksum="3A985B700981C2A6" modified="2018-01-31" version="1">MIQTTLTPFKNKLNSALTKKQITVLQINLGKRCNLACTHCHVEASPTRTEELSPEICDQLIEIIRKFPQIQTVDLTGGAPEMLYGFKRLAEAARATGKEVIVRSNLTIYFEKGFEDIPEYCAAHKLRIVASLPCYQADNVDKMRGNGVFDASIVALQKLNQLGYGKDSNLVLDLVYNPQVPTTDKFSLTAEQGKLQRDYQVYLAEHFGICFNHLFTITNLPVGRTKFHLEHKKLHRPYLGFLEDNFNPATIEHLMCRNELSIDYLGNVYDCDFNQMENLPAKTRTGETITVAKLLEFGSLDMIQEVQTAAYCYGCTAGSGSSCGGTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F232</accession>
    <name>A0A2G4F232_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PIN/TRAM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_008955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ycf81 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55806">
        <property type="protein sequence ID" value="PHX55806"/>
        <property type="gene ID" value="CP500_008955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="3">
        <location>
            <begin position="290"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="360" mass="39159" checksum="63FAC8988A2981DC" modified="2018-01-31" version="1">MLDAIIIISFIIAGGGIGFYGVELLPTNLLEQVTNIQGLSSVLGSFGALIGFVLGLVAQTTYRRVERQFRDMPVEMLLTRAIGLIIGLLVANLMLAPLFLLPIPREFGFIKPLVAVLGSVMFGFTGVSLTDTHGRAFLRLINPKALDATVLIAEGNFKPASAKVVDTSCIIDGRIENLLETGFLEGQIIIPQFVLQELQLIADSANDQKRVRGRRGLDILNRIKETYPERVQIHSADYEDIATVDAKLVRFALEIDGILLTNDYNLSKVATVQKLPVLNINDLTHAVRPTYLPGDTIDLKIRKEGKEPSQGIGYLDDGTMVVVEAGSSYVGAEARVVVTSALQTTAGRMIFARPQESLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F275</accession>
    <name>A0A2G4F275_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromophore lyase CpcS/CpeS</fullName>
            <ecNumber evidence="3">4.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cpcS</name>
        <name evidence="4" type="ORF">CP500_008490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CpcS/CpeS biliprotein lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.-.-.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55861">
        <property type="protein sequence ID" value="PHX55861"/>
        <property type="gene ID" value="CP500_008490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017009">
        <property type="term" value="P:protein-phycocyanobilin linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01459">
        <property type="entry name" value="Chrphore_lyase_CpxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018536">
        <property type="entry name" value="CpcS/CpeS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09367">
        <property type="entry name" value="CpeS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="202" mass="22904" checksum="17E23F94A46C44E8" modified="2018-01-31" version="1">MLLTPPMTMMDFFRKSEGVWFTQRTVHNFDTAAADESGESNVMIDVLSINDPRVLEVCQQQNVDPALVSGGCSFMWQDNLDDATPNQNYAAILIDVPNPNNPKMGKFLRNRGYVEGIPVIGIYNFADDGVLTIETEYETNQGQERCWFINDHFRVRVMTVQMSNGVKQMAYCSERRCISQSVLEEMLEHNRLRVYGAAAVSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2A4</accession>
    <name>A0A2G4F2A4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55891">
        <property type="protein sequence ID" value="PHX55891"/>
        <property type="gene ID" value="CP500_008325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="11989" checksum="89589BC56A8EFB16" modified="2018-01-31" version="1">MLTAVVIINLLISLVCFYIAARVWKVQRIIERFETRIIAINRCTSNVLIKSPNFLAKRQQAARQLRRNYLELELQLQQVQQLLGLLGLGRRFWRSRDRPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2C9</accession>
    <name>A0A2G4F2C9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55933">
        <property type="protein sequence ID" value="PHX55933"/>
        <property type="gene ID" value="CP500_008140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="71"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="168"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="227" mass="24407" checksum="F11D1D84FE596081" modified="2018-01-31" version="1">MSRNLTTIWTNAREVPSWLRIWSLCGLVAISSIASTPAVALQLASDTGNNSEIAQIGAGGLVRPALKFGNRGSEVRELQAALKLLGFYDDNVDGVFSQSTALAVSKFQETVGVTADGVVGQDTWNRLFPVATGAMESAIDNNTPTVENPQTNSQETQTSFPVLKRGMRGAAVRDLQERLRAKGFLRLRADGVFGRTTQAAVKAAQRQYKLPADGVVGSATWEVLLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2K4</accession>
    <name>A0A2G4F2K4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56004">
        <property type="protein sequence ID" value="PHX56004"/>
        <property type="gene ID" value="CP500_007560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="534"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="126"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="564" mass="63120" checksum="99043C446C9FA0AA" modified="2018-01-31" version="1">MAIRPYIKPRPGGPVFSLVQTTSRQGEILEVVFRNGWDYMKSVLTGRKTDAPSLPPPAVLRNILIELGPVFVKLGQLLSTRPDLLPTAYLDTLSSLQADVPPVPWSEVEVIIRQELKLSIAETFSQFNTQAVAAGSIAQTHKATLKDGREVALKVQRPGIDIIIERDIAVLKALAELVALTDYGQQYDIVALAEEFAIALRAELDFIQEASYTEELKRNLSKSRWFDPKQIVVPEIQWKLTTKKLLVMEWLDGVPILLGDLQGLRHNGDIDAEREEITTLLSRAFFQQLYIDGFFHADPHPGNLFYLKDGRIALLDCGMVGRLDPRTQQSLTELLLAIVDLDAQRCTQLTLQMAEFAQPTSLANLENDLAKMLRKYYNVSLSQMNLSEIFYEMLAITRKNKIRLPSNLGLYAKTLANLEGLARAFNPRFNIIEQVKPLMTDLFRRQLFGEDPVQALLRTALDLKSLSLQSPRQLEVLLDRVTSETLKWNLTVKEIDPLRRTLGDAANRLSFSIVVGSLIVGAAIISSNSQTAQLSFLSNGLFATASFLGLWLIVSILRSGRLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3G0</accession>
    <name>A0A2G4F3G0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Lipopolysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_006355</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56278">
        <property type="protein sequence ID" value="PHX56278"/>
        <property type="gene ID" value="CP500_006355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_31" evidence="7">
        <location>
            <begin position="595"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="775" mass="87145" checksum="CC19066392088324" modified="2018-01-31" version="1">MKPGKNSQISVFKKNKQAQVQQQSSSVFYQNDDFLELEQTETKKLNFWEVCRNRPLLVISVAAAVTTGVFAWTLTQKSEYEGRFQLLVEPAITQNTLAKIYSGELKLQPAAPSKSENPVFDYESQIQVLQSPQVMSPIIKQLRAKYPEINYNYLFSQKADSLQFFPATRLSINRFKNTKIIEVKYRDNDPKKIQFVLGKVALGYRNYSVKDPRNQISQNLDFVKSQIPNQQKRGQAIQTEIQKLRQQYNFIDPQIQTQQLAQQISQLQAQRLDAQTQLNQQRLLYGNLQAQLGLNQQQALMASSLSQAPRYQAMLTQLQQLEGQIAINSATYTDQTPQMQLFREQRKNLIPLLKKEAEQVLGTDLAKVNSQVLAFQDPVRIKLIEQFIGTANSIQVLGVRNQVLEQAAKQLSKYSQAFPVILRRYSDLQREADLTTNTLKNLLSKQQALQLEAVEKKEVAWEVIAKPEIPRYRNGELMAVAPIMPLNLALGGLVGLVFGTLVAQFAERFNNHKVFHTPEEVKHSIRLPLLGIIPASDKILRLPPAETVTVDVGSSQMPTDAFQEAFRSLNANIRLLNVDSPIASCVITSCQVADGKSTVAVNLARAAAAMGQQVLLVDADLRRPQVHEMLGLPNWQGLHNVIAEDLDVEKVILRSPRDENLFVLTSGPVPPDPTKVLSSRKMQHLMATLSSNFDLVIYDTAPLLGLADANLLAAHTNGLMLVVGLNQTEREALLLALEDLRMADIPLLGMVANNDKGSRYYYQSYVQNYIEEKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3H3</accession>
    <name>A0A2G4F3H3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_006300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56271">
        <property type="protein sequence ID" value="PHX56271"/>
        <property type="gene ID" value="CP500_006300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005891">
        <property type="entry name" value="DevC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031773">
        <property type="entry name" value="DevC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01185">
        <property type="entry name" value="devC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="303"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="394" mass="43677" checksum="8F690F54F308AF03" modified="2018-01-31" version="1">MLGLIKPLQQLRDRTPLGWLQLSHDKGRMVVAIAGIAFADVLMFMQLGFQNALFSSNTRVHQSLQADIVLIHPQARNLINLSSFPRRRLYQAMNVPGVKSAEPLYIKIGNWKNPETRRETSIMVVGFNPDRPAFALPEVNQNLNSIKLPDTVLFDRASRGNYQGSIAQINQGKSVKTEIDRRTINISGLFTIGASFAADGILMTSDQNYLRLFPRQDSASVNAGLIQLQPGADPVEVQQVLKAYLPSDVKVLTKQEFIDFEKNYWANNTAIGFIFNLGVAMGFIVGVIIVYQVLSTDVSDHMAEYATFKAMGYRNIYLLGIVFEEAIILSVLGFLPGVGVSIGLYHLTRNATNLPLYMTLMRAFAVLILNMVMCSISGTIATRKLQAADPADIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3K6</accession>
    <name>A0A2G4F3K6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_005960</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56328">
        <property type="protein sequence ID" value="PHX56328"/>
        <property type="gene ID" value="CP500_005960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="15"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="179"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="228"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="281"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="554"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="777"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="850"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="899"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="970"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="domain" description="PHYTOCHROME_2" evidence="6">
        <location>
            <begin position="1042"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="1238"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="1516"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="1565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1730" mass="196075" checksum="3D60FAA18C60380F" modified="2018-01-31" version="1">MKAVLNLAVHPTSFKVLLVEDNAYEAELIEDLLSGISGEQQISLTKVERLSEALLCLNQENFDVILLDLSLPDSWGIETVARVQEYAGNVPIVVLTGQNDEELALRLISVGVQDYLVKIKIDGELLMRSLRYAIERQNSQEALRKSEEKYRSVVENSLIGIAIIIPIIEPVIIENCNWIEVNDALCHLLGYQRDELIQKNWLDLTHPEDYSSHIEQLSQILAGTGDGYISDKRWLRKDGEIVYTRVSLRCIRRRDGSIDRMIKVVLDVSDRYRYESQLKASEQFLNHTINVIPDPIFVKDEQHRWMILNDAFCQLIGKPRSELIGKSDYDFFLKAEADFFWEKDEEVLNTGIPNETEENFTNSQGKEYIISTKKTVFQKTDGSKILVGTIRDVTEYRHQQIALEQSEARFQKLVANLPGAIYQFRLSASGEISFPYVSSGCREIYELEPELIEENAEIIFCKIHADDILDLEESIAISAATMQHWQQQWRYILPSGKVKWLQGASRPEVVNNETKAGNRSDIIWDGLVMDITELKQAQTERDRFFTISLDLLCIVDFDGYFRRLNPAWSTALGYSIAELFAKPMLEFVHPDDRAATVAEWKKLVGGTASICFENRYLCKDGSYKCLLWTASPFSEEGLIYSVGHDITSRKQAESTLQRQAVAMDAAYDGIAILNAQEEYIYLNYAYLKIYGVASPSNLFGKSWKMLYGEAEITIFERNIIPALKKTGHCNIEAIGQRCDGTLFPQELSMTMLAGGEIICIVRDITNRKQAESALRESQRRYQTLAEASPVCIFHTDLLGNCLYVNQRWNEITGISAELAAEIGWLNVIHSDDAERVNAEWYQAVIDRVPFKSEYRFLRPDGAVSWVIGQAVAEIGDAGEIKGYVGTITDISDRKQAELDLLRVTQAVESTSDAIVIGDLKGRSIYHNQAFIQRYGYTAAELNAAGGAMVIYPENKVLLEMFKTLRKGKSWQSELKIKTKANELVTTLFRADCIKDETGNLIGLVGVITDITERQQAEIALVQQLRRERLVVAMLDRIRSSLNLEEILTTAVEQVRQLLQTDRTVIYRFNPDWSGVVVTESVAKDRISLRNLNIDDPCFGQRFVDLYQQGWVRSVEDIYSADLTESHIKFLEQFEVKANLVVPILKAEKSISSPRLTTANRLWGLLIAHDCSGPRSWESSDIESLRQLCVQLAIAIQQSTLFQQAQTEIADRKQAEAALQKAALVAETANRAKSEFLANMSHELRTPLNGVLGYAQILKTDKTLNPDHQESLSNIQQCGQHLLMLIEDVLDLSKIEASKMELYPTELNFTNFIKNIADLFQMRASQKDIAFSYEQVSPLPNCVYVDEKRLRQILINLISNAVKFTNSGGVTFKVGYVGTEAWMRGQEESCEFSILSSELKQNYMRFSQNGMSDKYTLKIRFQVEDTGTGIDESKLEEIFLPFHQVGTNRFVEGTGLGLSISRKLAKLMGSEIRVKSTLGQGSIFWLDLELPAPKLYSEVLPLQERRWLVGFVGEKRKVLIVDDNQVNRSMLCRLLSSLGFEIAEAENGQECLYKAVEFKPNVILMDLLMPVMDGLETARRVRQLPELKDVVLIALSANVFENTQQESILAGCDYFMSKPIEANLFLEQLRLHLGLEWIYEDYLDGKKRKTASLSPKSELPNYSSLLPPVAESVVKMFNFAAMGDIEGIFDEAVKLEGLEPKLMLLITHVRQLAKKFGLKQIRTLLKQYIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3M1</accession>
    <name>A0A2G4F3M1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56077">
        <property type="protein sequence ID" value="PHX56077"/>
        <property type="gene ID" value="CP500_007145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="199"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="395" mass="45033" checksum="0B19EDC25BB43472" modified="2018-01-31" version="1">MKILVLAWEFPPRIVGGIARHVSELYPELVKLGHSIHLITVEFGNAPMYEVVEGIQVHRVVVGHARDFFHWVANLNQSMGHQGGKLILEEGPFDIIHAHDWLVGDAAIALKHTFKVPLIATIHATEYGRFNGIHNEGQRYINTKENSLAYNAWRVIVCSDYMRREAERVLSTPWNKIEVIYNGIRSEKKPRLNELDARDFRRKFAADDEKIVYYVGRISYEKGIAVFLNAAPKVIWKMGGKAKIVIVGGGNTDYLKYQAWKLGIWNKCYFTGFMFEEDLDKFQTVADCAVFPSLYEPFGIVALESFAARVPVVVSDAGGLPEVVQHTKTGVVTQANNSDSLAWGILEVLNNPGYGQWLVDNAYEDLERRFSWQKLAMETEWVYQRVVEERAEVDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3R3</accession>
    <name>A0A2G4F3R3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56424">
        <property type="protein sequence ID" value="PHX56424"/>
        <property type="gene ID" value="CP500_005300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8566" checksum="E0320CA0B93F877B" modified="2018-01-31" version="1">MTFEAVLNLVKQLSLAEKLRLIKSIVPEIERELVVMPTPRKSLWGLCADLGIAPSAADIDEVRREEWANFPREDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3R6</accession>
    <name>A0A2G4F3R6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Toxin-antitoxin system, antitoxin component, Xre family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56399">
        <property type="protein sequence ID" value="PHX56399"/>
        <property type="gene ID" value="CP500_005660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7928" checksum="FF2E3AB1D596A324" modified="2018-01-31" version="1">MSITQNPEAELMEKIRSLPPDKITVLEDFIDFLLTRSEAHLLVYTATKLSEAAFAKIWDNPEDAEYDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3U8</accession>
    <name>A0A2G4F3U8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ORF">CP500_005265</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56418">
        <property type="protein sequence ID" value="PHX56418"/>
        <property type="gene ID" value="CP500_005265"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="32"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="114"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="313"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="116"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="461" mass="50059" checksum="22001D4DBA4BE845" modified="2018-01-31" version="1">MVCRVTICQLAEILTVPVPMASEVVLTTLGIGIATDTRTIQGGEVFLALRGENFDGHQFVEKARDLGAIVAVVDRAWEGTVPNFPLLRVDNTLTAYQAIARWWRDQFTIPIVAVTGSVGKTTTKELIAAVLSTQGNVLKTQFNYNNEIGVPKTLLELSPEHNYAVIEMGMRGLGEIAVLTQIARPTVAVITNVGTAHIGRLGSEEAIAIAKCELLAEMPADSIAILNQDHDKLMTAAAKVWEGKTLTYGLEGGDLCGEFLDNNSMRIQDIQLPLPLPGQHNAVNYLAALAVAKVLDIDWEFFTQGLSVQLPDGRARKYELPNDIVILDETYNAGLESMLAALRLLADTPGKRRIAVLGTMKELGDKSLAFHKKVGTAALNLNLDALFIFADFEEAVAMAAGATGLPLVEIEDVAAANSHEVLARHLMEFVETGDRILFKASHSMELNRVVEKFRTDMTVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3V6</accession>
    <name>A0A2G4F3V6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56429">
        <property type="protein sequence ID" value="PHX56429"/>
        <property type="gene ID" value="CP500_005335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="11"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="198"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="244" mass="28237" checksum="0F4F5C228CE031C1" modified="2018-01-31" version="1">MVLISTQKLTFQEYLNYQGESGVCYELYRGEIIEMPTPTAIHIKIIAFLVYQFRCFFAAHNLPLVAVVTTAVRTEENSSRVPDVLICTQSLWEQICAKPGSAILDFEEKPLLVIEVTSQNWRDDYIRKRAEYDLIDIPEYWIVDPNQPKIRVCSRPENEGSYSQQEFLPGQQVQSVQFAEFILSVNQVLSPPLVEDLIREEQAQLQQLGQQNQQVGRQNQQLEQQVERLSQRLREMGVDIDTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F454</accession>
    <name>A0A2G4F454_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56542">
        <property type="protein sequence ID" value="PHX56542"/>
        <property type="gene ID" value="CP500_004645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="100" mass="11029" checksum="F0384A39BF0CDA57" modified="2018-01-31" version="1">MLTNPIKYVYKSQECFKLAISRSPLNQTIADRPRPGKPRSPWLLIAAIAQNPPISYQNPQSPQISPGINSSIQNPKSQIQNRLTAAPICGYALKLEVACL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F482</accession>
    <name>A0A2G4F482_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56594">
        <property type="protein sequence ID" value="PHX56594"/>
        <property type="gene ID" value="CP500_004455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="104" mass="12056" checksum="A8B4809D5804245B" modified="2018-01-31" version="1">MPQQESSAFPENFPDPKLPAAVEVDEMLTRIKHSHGHYYKVMNLEVWALVETLDQVFPGAWGHFMANRQVAVKQFLQRSRDPNSSVDAEEVEDKEERSRKQEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4E2</accession>
    <name>A0A2G4F4E2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NAD(P)H-quinone oxidoreductase subunit M</fullName>
            <ecNumber evidence="9">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">NAD(P)H dehydrogenase I subunit M</fullName>
            <shortName evidence="9">NDH-1 subunit M</shortName>
            <shortName evidence="9">NDH-M</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ndhM</name>
        <name evidence="10" type="ORF">CP500_004450</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the complex I NdhM subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56616">
        <property type="protein sequence ID" value="PHX56616"/>
        <property type="gene ID" value="CP500_004450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01352">
        <property type="entry name" value="NDH1_NDH1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018922">
        <property type="entry name" value="NdhM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36900">
        <property type="entry name" value="PTHR36900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10664">
        <property type="entry name" value="NdhM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="5 9" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="3 9" id="KW-0874">Quinone</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="6 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="13257" checksum="09675953828264CC" modified="2018-01-31" version="1">MQLKSTTRHIRIYTAILEDNELVPSNDLLTIDIDPDNELNWNDESVKQVYAKFDELVDSYEGEDLTEYNLRRIGSELEHLVRSFLQKGQISYNLNSRAVNYSMGLPRVDAKIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4E6</accession>
    <name>A0A2G4F4E6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA phosphorothioation system sulfurtransferase DndC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dndC</name>
        <name evidence="3" type="ORF">CP500_005805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245726">
        <property type="entry name" value="M.Tbo703DndCP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56357">
        <property type="protein sequence ID" value="PHX56357"/>
        <property type="gene ID" value="CP500_005805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017598">
        <property type="entry name" value="SulphurTrfase_DndC_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03183">
        <property type="entry name" value="DNA_S_dndC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="2">
        <location>
            <begin position="44"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="560" mass="64957" checksum="A3B8512C41733F61" modified="2018-01-31" version="1">MIEVQQMSLFEPRTVKELLEEIKELTKEIQELYCLDAIPWLIGWSGGKDSTAVLQLIWNAIAALPIEKRTKTVHVITTDTFAENPIISAWVRKSLANLKILAQEQKMPISPHLLHPEVKETFWVCLIGKGYPAPRNGFRWCTDRMKIQPVNQFIRDIVRVHGETIVVLGTRKAESSKRAATMKKYEAGRLRDRLSPNARLPNSLIYTPIEDWRTDEVWLYLMQWDNPWGNNNKDLFMMYRGATADNECPLVVDTSTPSCGDSRFGCWVCTMVDKDKSMEAMIQNDEEKEWMQPLLDIRNELDIKNDRPKRDFRRIYGRVELFERNMGDDKTSVEPIPGPYTKFWREHWLRRVLEAQTHIRKTAPLEMRDITLITPEELSEIRRIWLEQKHEFDDSLPRIYEEVTGERFEDSRPAAERKLLGSDEWTVLEEMCDDKMHLELMAKLLDTERQYYTKPRRTGVYGDLEKCFETSSRSQKEAIGNAHYQRNLKKAVEDVKANPALNIQQVKDAIAQTNLSATDATVDIAKLKEELESSSNEDRQLSWADIKYSTPDSGGGNGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4F3</accession>
    <name>A0A2G4F4F3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutathione peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_004495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56618">
        <property type="protein sequence ID" value="PHX56618"/>
        <property type="gene ID" value="CP500_004495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011906">
        <property type="entry name" value="Glutaredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PTHR10430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02190">
        <property type="entry name" value="GlrX-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="4"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="244" mass="26668" checksum="2FF86FA37971D342" modified="2018-01-31" version="1">MLPNKEGQRVPTVTFRTRKDNEWVDVTTNDLFAGKTVVVFSLPGAFTPTCSSTHLPGYNELAKVFKANGVDEIVCISVNDTFVMNEWAKDQEADNVTLIPDGNGEFTEGMGMLVDKTDLGFGKRSWRYSMVVKDCVVDKMFIEPEEPGDPFKVSDADTMLHYINSAAAKPKVVSLFTKVGCPFCARAKAMLTEKGLDYEEIVLGQDITTRSLRAVTGATTVPQVFIDGKLIGGSEALESYLAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4M3</accession>
    <name>A0A2G4F4M3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13 14">UvrABC system protein B</fullName>
            <shortName evidence="13">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrB</name>
        <name evidence="19" type="ORF">CP500_004205</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 13 14">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the UvrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56700">
        <property type="protein sequence ID" value="PHX56700"/>
        <property type="gene ID" value="CP500_004205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13 14" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 13 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 13 14" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 14" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="29"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="433"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="16">
        <location>
            <begin position="631"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="255"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="13">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PHX56700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="670" mass="75974" checksum="46740AE9FDA88876" modified="2018-01-31" version="1">MITAAASFKLQAPFEPTGDQPVAIAQLVKSIQAGDRFQTLLGATGTGKTFSIAAVIEKIGKPTLVLAHNKTLAAQLCNELRNFFPNNAVEYFVSYYDYYQPEAYIAVSDTYIEKTAAINEEIDMLRHSATRSLFERRDVIVVASISCIYGLGMPAEYLKAAIPLRVGMEVDQRQILRDLVNVQYSRNDIDLGRGKFRVKGDVLEIGPAYEDRIIRVEFFGDEIDAIRYVDPVTGKIIQNVEALNIYPARHFVTPKERLESACTAIEQELEARLEELEKNGKLLEAQRQEQRTRYDLEMLREVGYCNGVENYSRHLAGRNAGEPPECLINYFPKDWMLVIDESHVTVPQIRGMYNGDQARKKTLIEHGFRLPSAADNRPLKAEEFWEKANQCIFVSATPGDWEIEISGDRVAEQVIRPTAVVDPTIFVRPTAGQIDDLLGEINERVRLNERVLVTTLTKRMAEDLTEYLQERAIRVRYLHSEIQSIQRIEIIQDLQDGKFDVLIGVNLLREGLDLPEVSLVVILDADKEGFLRSGRSLIQTIGRAARHIRGQAILYADNLTDSMVKAIDETDRRRGIQLAYNKMHGITPQPIAKKRSSNAILAFLDVSRKLNSQQLEEVYEHANELSLDEIPQLIGRLEAQMKEAAKKLEFEEAGKLRDRIKHLRDKLLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4N6</accession>
    <name>A0A2G4F4N6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aldo_ket_red domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56695">
        <property type="protein sequence ID" value="PHX56695"/>
        <property type="gene ID" value="CP500_004180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="25"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="11245" checksum="F638DBEA190E6472" modified="2018-01-31" version="1">MNGIPENSRLALFAGFGQRYDKTNLNDAVKAYVEIAGKYNLTPARMALAYVRSRWFVTSTIIGATSLEQLEENLSSLEVELDREIVAEINAVHAKYPNPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F510</accession>
    <name>A0A2G4F510_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56874">
        <property type="protein sequence ID" value="PHX56874"/>
        <property type="gene ID" value="CP500_003095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045738">
        <property type="entry name" value="DUF6088"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19570">
        <property type="entry name" value="DUF6088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="27123" checksum="BD6C81BF3E8D5650" modified="2018-01-31" version="1">MKRSQVNTAELIRRQIEERPEGYWRHSDFSNLPSTAVSKALSRMAENGILERVSKGLYYRSRPTRFGRSRPSPSDIQKLLTKQNLHPAGLSAANLLGFTTQNAIQGEFATSANSVPRTIIGSRARLHTRRPETWNRLEATDAAMLDFLRSRGKLSELSLTETKQRLLDYFREGSRFERLLAVADAEPPRVRAMLGAIGQELRKSLKELEKLRKSLNPVSRFDFGNFSNLSYAKEWQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F544</accession>
    <name>A0A2G4F544_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56866">
        <property type="protein sequence ID" value="PHX56866"/>
        <property type="gene ID" value="CP500_003055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="12419" checksum="183B8F196DBCA194" modified="2018-01-31" version="1">MNYQNDFNWQQALGELKAKLDRSPLIKINLDNYPAVQTFYNQFLEKFQSLPKPGQVAVFAVAAIILLTVFNTVVQLISALITLAVLGAIIYITYKLAISPDSSNTNNTRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F599</accession>
    <name>A0A2G4F599_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56881">
        <property type="protein sequence ID" value="PHX56881"/>
        <property type="gene ID" value="CP500_003140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="16456" checksum="CF967B3B65EF8265" modified="2018-01-31" version="1">MTRLYYRGMAEENGKPKIGRNARLLGVRPAIDIDVEQVPKEWLDEQGYLRPETERNSSEESVTVAIRNTKGMSVSLSIEGLPPFRKPPKFGGTGKDPLWQIDDSKIVGDIEAVQDSPTHVSILPSATMLLEKYETALAQTQSEWEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5J2</accession>
    <name>A0A2G4F5J2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Copper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57009">
        <property type="protein sequence ID" value="PHX57009"/>
        <property type="gene ID" value="CP500_002125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="100"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="2">
        <location>
            <begin position="226"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="334" mass="37383" checksum="51ADE702E40627B2" modified="2018-01-31" version="1">MADLSDRSVIKMAGRLSRRQLLQLGMAGAGVAGGAIALQNLTQKRPAAARIPPIPADAPAVSNINPMQIVRDFDYGTVTRENGRTVREFRMEANTSIVQLNSAVTFNTWNVNNRVPGPTLRATQGDRIRVIFSNKAGHSHSLHFHGFHTSEMDGIKPVRNGSVFIYEFDATPYGVHLYHCHIAPVTRHIGKGLYGMFIIDPPKPRPPADEIVLIMGGYDVNDDEKNELYAFNGLPHYYMKNPISIYKNQLVRLYVLNMIEYEAAVTFHLHANFFDVYRTGMTLTPSERADVITMGVAERHILEFTYGYNGKYMFHPHQDAIAEAGCMGIFEVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5K5</accession>
    <name>A0A2G4F5K5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57083">
        <property type="protein sequence ID" value="PHX57083"/>
        <property type="gene ID" value="CP500_002045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="84" mass="9656" checksum="C3757E2897D9436A" modified="2018-01-31" version="1">MSQIWTEEQIRQIIPDIDSQLDDSDIPTVIIKGEGSSIFLQFENRREIEFLISQLSNLLIHHEELDLGVTVKGYVTTFGEYSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5M3</accession>
    <name>A0A2G4F5M3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57072">
        <property type="protein sequence ID" value="PHX57072"/>
        <property type="gene ID" value="CP500_001985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018335">
        <property type="entry name" value="Tscrpt_reg_HTH_Crp-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00325">
        <property type="entry name" value="Crp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00042">
        <property type="entry name" value="HTH_CRP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH crp-type" evidence="2">
        <location>
            <begin position="151"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="250" mass="28601" checksum="1C2FF72A195C0B85" modified="2018-01-31" version="1">MQSTSTSLETIDRPFITWQRIIDWAQEHYRCRTFNKDERIPARPGLLYLVQKGSVRLVGSAQVSATGKLSKSTDEAPEEAFLGFVGAGQPFELVAQSPFTLQAYAHADQTHVVWMYWHDLDNWPHFRREIMDAFRYQHQRKLLWLSTLGQRRTIDRLLGFLTLLIEEFGLPYVSEAEPDVVRGYRLPWALTHAQIGSAIGSTRVTVTRLMGKLRSKGLINTEDDNLICLPANPESAKAKNQNKQTEEPME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Q7</accession>
    <name>A0A2G4F5Q7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57086">
        <property type="protein sequence ID" value="PHX57086"/>
        <property type="gene ID" value="CP500_002060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="4"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="120" mass="13760" checksum="427D3894B6A0D45E" modified="2018-01-31" version="1">MAIQYLFDENVDPAYVNQIRRRNPALVVLAVGELTAPSKGTLDPEILIWCEIHNFILVTNNRRSMPVHLIDHLEQNCHIPGIFILNFKLSIGQNIDELILICQGSFDDEYQDKIEHLPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5T1</accession>
    <name>A0A2G4F5T1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MotA/TolQ/ExbB proton channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_003360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56847">
        <property type="protein sequence ID" value="PHX56847"/>
        <property type="gene ID" value="CP500_003360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="9">
        <location>
            <begin position="69"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="219"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="265" mass="29185" checksum="4628603334BDEEBD" modified="2018-01-31" version="1">MNIQELFEKGGPAMWPLLVLSILSVSTIIERLWFWASLLTKEKQIVNRILDAARSDWGAANEIARQASRQPIGRFLSAPLRLYNPEPELFRLALEAAADEELASMRRGDKVLESVIALAPLLGLLGTVLGLINSLSSIRLGDIGTSATTGVTLGISEALITTATGMVVAIFSLTFYRIFQAFLFNQAKIFRKAGNELELLYRQYWPTANAQGRSAAEAEYGKSSFGSDRLNKHSWNSQPESGERNREPKPKLKGSDPDVDSTSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5V5</accession>
    <name>A0A2G4F5V5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56867">
        <property type="protein sequence ID" value="PHX56867"/>
        <property type="gene ID" value="CP500_003060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013854987" evidence="1">
        <location>
            <begin position="35"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="149" mass="15762" checksum="70331F603FE902A2" modified="2018-01-31" version="1">MKIHYPCDRARPRLSSIATLALAMILAPVSTVGSQPLQIAPGFPEPLSVSGVSGGPNNSGDCGFVSQAPNHVIQVTQDLHYWRIAVQTAGAPSLMIQGPRGRFCVLPANAATAIVEFSGYGDKGTYAIFVGDRAQGQHPYSLSISQKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Z6</accession>
    <name>A0A2G4F5Z6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57180">
        <property type="protein sequence ID" value="PHX57180"/>
        <property type="gene ID" value="CP500_001245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="137" mass="15894" checksum="CD522BB0FE49E59E" modified="2018-01-31" version="1">MNNPIIWLHGDCLSPESPAFQLHPEAKAIWVWDDALIDEWQLSLKRMVFIYECLLELPVVIRRGDVAAEVLAFAKESGANQVVTAESPSPRFQDICLEITRSLPVEILPPEPFVRYNGYIDLKRFSRYWRVAEKYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F621</accession>
    <name>A0A2G4F621_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57198">
        <property type="protein sequence ID" value="PHX57198"/>
        <property type="gene ID" value="CP500_001360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="13057" checksum="D4A1310A635B5AD1" modified="2018-01-31" version="1">MDRPPLPQPKLDPTPITFDQYDAYTPEKLELWDGFYNYGGQNLTGFHLAVLANMGLRKAVRNVPLSLWLEAIQELALQNSKLNFDTEMGEAMLNRLNRGLEDLQSVAEYLEEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F625</accession>
    <name>A0A2G4F625_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57210">
        <property type="protein sequence ID" value="PHX57210"/>
        <property type="gene ID" value="CP500_001445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="84"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="458" mass="52345" checksum="4A8E96FCD36D2894" modified="2018-01-31" version="1">MLRFISHRLQPPRDRLLKDVKREVQASRSHSLHNAVLSNLRQETAPPGVSRCWDVDVKVGNRPSFRLPPKASIAKVFDRTGGKLVILGATGAGKTTTLLELAMVLISRAQKDPSLPVPVLFELGAWKTESGAIADWLIAQLQFKYDIPAAVGKQWLTEQKLLPLLDGLDEVKPHRQNFCIQAINQFVESDFKPKHLVVCSSFEVYKDCPNRFRLQAAILLKPLTETQIQNYLLEARSRELWYSIEKEPELLKLAKAPLFISMMALAYEDILIEAWKRIPSPEEQRKYLLTAYIRRQMTGEVKQYPRSTGKELRSEQIRNWLGWLARKMEQQGIQEVLLDKMPSSWLETVEQQRVYQFGTKLLGGLIWVILGLVLTLVSGSIWGLIAGAIAAIISALLPSIPMIHNFVLHLVLWSNGYIPWNYSRFLDAAADRLLMHKTGDRRYRFVHNLLQKHFAEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F672</accession>
    <name>A0A2G4F672_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Precorrin-4 C(11)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cobM</name>
        <name evidence="8" type="ORF">CP500_001055</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57294">
        <property type="protein sequence ID" value="PHX57294"/>
        <property type="gene ID" value="CP500_001055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046026">
        <property type="term" value="F:precorrin-4 C11-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11641">
        <property type="entry name" value="Precorrin-4_C11-MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006362">
        <property type="entry name" value="Cbl_synth_CobM/CibF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01465">
        <property type="entry name" value="cobM_cbiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="13"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="259" mass="28347" checksum="9BBBB46D8698572A" modified="2018-01-31" version="1">MSLTKAKSLMPGVYIVGAGPGDPDLLTVKAQKLLAVADVILFADSLVPEQILQGVRADAEVIQTADKTLEEIVPLMVERVRDRKSVVRLHSGDPCLYGAVGEQMQGLAAAGINFEVIPGISAFQLAAAKLKIELTVPGIVQTIILTRISGRTEVPQREELASLAAHQASLCLYLSARHVEQAQAKLMEHYPADLPVAICYRLGWPDEKILLVPLDKMAVATRENNLIRTTMYVISPALGNEVEGRSRLYHPEHDRLFRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F678</accession>
    <name>A0A2G4F678_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57293">
        <property type="protein sequence ID" value="PHX57293"/>
        <property type="gene ID" value="CP500_001005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="51"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="425" mass="48231" checksum="DF33A89BC7FFC25C" modified="2018-01-31" version="1">MLIGFSVGNYKSFKETVTLSMVASSITEEEKELDANNLFEINHKLNLLKSAAIYGANSSGKSNLIAAINFMKWFVLNSSKETQVSEAIDVEAFRLSTETEKEPSFFEIVFLLEGKTFRYGFEVNAREVVSEWLSQADDSEEKMLFERDFDKCILGDFPEGQGISDKTRSNALFLSVVAQFNGKISGKILLWFSKTLQLISGLQDRQYRKETLESFENDRHRHDIIEFIKKLDLGIADIQITNQPAFIISNNKALYARSYGGSLYLNSESKPTVKTIHPKYDADGKQTAIELFDIEKHESEGTNKLFALAGILLDTLRIGKILLIDELDARLHPLITRELIYLFNSNVTNPHNAQLIFTTHDTNLLSSKTFRKDQIWFTEKDNKGATDFYSLVEYKVGKNASFEDDYIIGKYGAIPFIGNFKELIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6F2</accession>
    <name>A0A2G4F6F2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dethiobiotin synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57067">
        <property type="protein sequence ID" value="PHX57067"/>
        <property type="gene ID" value="CP500_001960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12745" checksum="22424756681D5684" modified="2018-01-31" version="1">MDYKTARSFLIDQGSALETKKNPDAFLMRLQQGLSPVPGQVTAILLALKILFEGLQESPMLDRQLISALHLLSVESLQQFEAGVRRGVSWPPLLKEDLNRIAIAVRNIFSGVWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6I5</accession>
    <name>A0A2G4F6I5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57404">
        <property type="protein sequence ID" value="PHX57404"/>
        <property type="gene ID" value="CP500_000240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="117" mass="13931" checksum="85A31103F172AC58" modified="2018-01-31" version="1">MDKLEYYRDTIKKILTEYYQMKVQGAIELDELEPDDRLAFDEERDQYLWFRSGWNGKERLRYMTMYLRIKDGKIWVEEDLTNLCVVDDLLAAGISKGDIVLGFRHPSKRPLTEFATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6M1</accession>
    <name>A0A2G4F6M1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BrnT family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57400">
        <property type="protein sequence ID" value="PHX57400"/>
        <property type="gene ID" value="CP500_000215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038573">
        <property type="entry name" value="BrnT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007460">
        <property type="entry name" value="BrnT_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04365">
        <property type="entry name" value="BrnT_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10695" checksum="D8EA091FB79DE6D4" modified="2018-01-31" version="1">MEFEWDETKRLANLSKHGIDFIDVPLVFDGEIVTVEDERFSYSEQRLVTFGLLQGRVVAIVHTEREDSTRIISARKANKYEQRIYFEQIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6R0</accession>
    <name>A0A2G4F6R0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-binding cassette family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_001225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57177">
        <property type="protein sequence ID" value="PHX57177"/>
        <property type="gene ID" value="CP500_001225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="3">
        <location>
            <begin position="5"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="243"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="607"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="719"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="856"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1076" mass="123711" checksum="4E049A09D2C7AA38" modified="2018-01-31" version="1">MIPIQLTLKNFLSYREAALDFRGLHTACVCGPNGAGKSSLLEAITWAVWGCCRSDSEDEIIHMGEIDVRVDFTFATGGQIYRVIRNRRRGQSGSLEFQVATNPPFPPLGKGGPEEVNSSLGKGTPEEVNSSPPLSKGGLGGVNFRTLTDKGLRTTQQKILEHIKLDYDTFINSAYLRQGRADEFMLKKPIERKQVLANLLKLDQYDTLSEQAKDQSREFKAEVEVLKHSLQTTQEQLQQKDAIATEQSQLQQATTQLQQQQQIDTAHLQQLQLQHQNRQTWQTLLASHQQQHTNISQECRRLQQELAAAKQQQNELQALLTQENEITTGITYFHNLQATEETLAGKFKAHQQAQNQRSQLQEQQRQELSLLQGKIQQLQAQLDVLEQDEKEVLQVLKQQPEVEKGLVQLQAVRSQLNQLEQLQLQVSPLLQQQQQTQTKLDRAHAGLTARLQEINRQLQVQQHQRQPQLQREISAIADQILQLENKRVYQQRVREKGRERHNFLENLQTKSRDYQTRLTEIDQKLQLLRKDESEKSVEASVRVESKTVNFAENEQSNSHLTVRDADFGNCPLCDRPLDEHYWNLVVKKHHSQQQEIWNELWVVREQLAVSEREIQVLRHEFRQLEAELAPYEELRERRANLQAQLDALGKDENRLQSMRKDAAEIERSLRTGDYASDEYAQLQEIELQLKQLNYSDRNYSLARSEEKRLRWVEIQQSKIKDAQQKLNINNARRPELQNQLITFKQQLEQQKERSETQQQILSLDRYIGEVGYNLEQHEHVRSEMRRSQFWIARAEKLRSATQQHPQVQQRVNEIASSIAVRDRDLQAVSAQLSAMSKQLQENPDPTTRISAIEQQINRRRQQLDQHLGNLGRLEQQQQNLEALQVQLIAQKEQMQVAKRQQRVYQELGQAFGKNGIQALMIENVLPQLEAETNQILSRLSANQLHVQFITQRAAASKKATKLIDTLDILIADARGTRPYETYSGGEAFRINFAIRLALARLLSQRAGTALQMLIIDEGFGTQDAEGCDRLIAAINAIASDFACILTVTHMPHLKEAFQARIEVNKTAQGSCISLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-12-20" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2A5P1L5</accession>
    <name>A0A2A5P1L5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_004250</name>
        <name evidence="7" type="ORF">CP500_022345</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000224">
        <property type="protein sequence ID" value="PHX53277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53277">
        <property type="protein sequence ID" value="PHX53277"/>
        <property type="gene ID" value="CP500_022345"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56630">
        <property type="protein sequence ID" value="PHX56630"/>
        <property type="gene ID" value="CP500_004250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="181"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="311"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="430" mass="48979" checksum="447B087D10C0FF83" modified="2017-12-20" version="1">MQLTERHIIKSTEHRFAQIDELAFKSKNLYNAANYVIRQSFIYGWGYVNYNEMNRLMKSHEAYKALPAKVSQQILMVLDKNWKSFFEAVKAYKADSSKFTGRPKLPKYKDKTKGRNLLVYTIQAISSKQLKKGIIKLSGTELSIKTQLNPNHICQVRLVPKCDSYVIEVIYDACTERSRSEPESTLGNANSVASIDLGLDNLVALTSNQPGFIPLLINGRPLKSINQFYNKRKSRLQSQLKRNRQTSPRIQRLTRCRNQKVDNYLHHASRVIVDHLVVNQIGTLVIGKNAQWKTDINLGKQTNQNFVSIPHSRLIEMLEYKARLAGIKVIVQEESYSSRANFLCLDPIPVYGKTEKETVFTGKRIKRGLYKTSTGQLINSDINASYNILRKAIPNAFSDGIESCVVQPRRVNPLKVKVKGEGLEASHAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUI0</accession>
    <name>A0A2G4EUI0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_023055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000262">
        <property type="protein sequence ID" value="PHX53148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53148">
        <property type="protein sequence ID" value="PHX53148"/>
        <property type="gene ID" value="CP500_023055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12530" checksum="E95C3855DD759052" modified="2018-01-31" version="1">MTNQGVLNRRQFLMSLCIPAIAKFPTKSESPLPGVCQPEFWFGELVDFCWIDEISGQSHSERGQVIGVVWNPTEKEWEYRITWLSSTAYPGDDYPICDDNLVSAEVLCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUL4</accession>
    <name>A0A2G4EUL4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molybdate ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">modA</name>
        <name evidence="4" type="ORF">CP500_023010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein ModA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000258">
        <property type="protein sequence ID" value="PHX53156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53156">
        <property type="protein sequence ID" value="PHX53156"/>
        <property type="gene ID" value="CP500_023010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13537">
        <property type="entry name" value="PBP2_YvgL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005950">
        <property type="entry name" value="ModA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041879">
        <property type="entry name" value="YvgL-like_PBP2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004846">
        <property type="entry name" value="ModA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01256">
        <property type="entry name" value="modA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004846-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="264" mass="28407" checksum="70EC400839049A3A" modified="2018-01-31" version="1">MKKRVIAFFSSLLVTLILSGGLNIVSPLPAEARSTTLLIGAAASLQNALEELDPIFEKANSGVAVNYNFAASGPLQQQIAQGAPVDVFISAATLQMDKLQNENLILNDTRHNLLTNNLVLIVPNNSALGLTNFRQLTNSNVRKIAIGEPRSVPAGRYAAELFSKLGITEQVRSKLVYGNSVRSVLGAVESGNADAGVVYVTDAKMDDRVKQVATAPSNLHSPIVYPIAVIKASRDPQSARAYVQFLRNRQAQDIFKKYGFGIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUQ7</accession>
    <name>A0A2G4EUQ7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_022330</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000223">
        <property type="protein sequence ID" value="PHX53282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53282">
        <property type="protein sequence ID" value="PHX53282"/>
        <property type="gene ID" value="CP500_022330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="63"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="750" mass="82188" checksum="53790E26680C3BE5" modified="2018-01-31" version="1">MTPPQPPHKPQTVLGAITQAVQTIAKVNFNQLVLKPNAKVPELWVQDAGAAKAEVYPLLGDRYLLGRSSKSSDIVIRNPVVSHLHLSLSRDTRLGTPFVIKDENSTNGIYRGKKRIESMSLRHGDVFTLGPPELADAVRIQYIDPPPLYSKVLRYGFYGISGATALIGMLIGIESTKFQVRPLPRSVNGPVIVYARDGQTPLRPPQNNAHLELKTLPDFSPYLAKAIIASEDSRYNWHLGVDPLGVLRALLTNFRGGGIREGGSTLTQQLARSLFRDYVGTQDSAGRKFREAIVALKLESYYSKDELLLTYLNRVFLGIDLYGFEDAARFYFGKSAKDLTLSESATLAGILPAPNSFNPIQNYQLAVQYRDRVIERMRVMGTISQEEADRARRSRIEINPKAREFLQSTIAPYFYSYVFDELEFLLGEQLAREGNFIVETGLNPSLQKLAESSLRNAVENSGARAGFSQGAVVTLNTKNGEVLALVGGVNYRQSQFNRATQALRQPGSTFKIFSYTAALEQGIPASKSYSCEPLSWGGQSYSGCERTSGSADMYRGLAQSENAIALRVAQDVGLENVVRMAKRFGITSPLRSAPGLVLGESEVNVLQLTGAFGVLANRGLGNRPHVIKRIIDSSDCQDIKNFKTCRVVYDYQKDGVANQQLVSEVAADTMTDMLQGVVRGGTGSSAALGLGEAGKTGTTNDNKDLWFVGYIPSEQLVTGVWLGNDDNSPTQGGSRDAAQLWGDYMRQVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUQ8</accession>
    <name>A0A2G4EUQ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SPFH/Band 7/PHB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000227">
        <property type="protein sequence ID" value="PHX53265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53265">
        <property type="protein sequence ID" value="PHX53265"/>
        <property type="gene ID" value="CP500_022435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018080">
        <property type="entry name" value="Band_7/stomatin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01270">
        <property type="entry name" value="BAND_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="19"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="321" mass="35603" checksum="9037DCBB1B9310B5" modified="2018-01-31" version="1">MEQLFLFVFLALGGSTLAGSVKIINQGNQALVETLGKYSGKKLEPGLNFVTPFLDRVVYEQTIREKVLDIPPQACITRDNVSFTVDAVVYWRIVDLEKACYKVENLQSAMVNMVLTQIRAEMGQLDLEQTFTARSQINEILLRDLDVVTDPWGVKVTRVELRDIIPSKTVQESMELQMAADRRKRAAILTSEGERESAVNSAKGKAEAQVLDAEARQKATILEAEAQQKAIVLRAQAERQSQVLKAQATAESLQIIGKTLQTDPNAREALQFLLAQNYLDMGLKIGTSDSSKVMFMDPRSIPATLEGMRSIVGEGNNEVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUR7</accession>
    <name>A0A2G4EUR7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000225">
        <property type="protein sequence ID" value="PHX53275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53275">
        <property type="protein sequence ID" value="PHX53275"/>
        <property type="gene ID" value="CP500_022385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="55"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="397" mass="43858" checksum="F3CE6D02D4E05E2F" modified="2018-01-31" version="1">MPHALCPMPNLLSFTLLLLQFPAVAILMSRLIKGPSRIPPLEPESPTLDLLGACTVVVPTLNEADRISPCLDGLSRQSYELREVIVVDSYSVDGTADLVKTAGEKDPRFRVINDDPLPAGWVGRPWALHTGFLASSEKCEWILGIDADTVPHPGLIASLLKTAIAGNYDLISLSPQFILKYPGEFWLQPALLMTLVYRFGPTGTGGDVPELVMANGQCFLCRREVLVELDGYESARGSFCDDVTLARYAAAKGFKVGFLDGAKVLQVRMYEGAIETWNEWGRSLDLKDAASRAQIWGDLWLLFAVQGLPVLILLGYLLFGWRSPVVLFPYGWLLGLNVFLVAVRSALCFAIAPSYDRTNASGQWLFWLSPLADPLAFLRILISALNQPTQWRGRKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUV7</accession>
    <name>A0A2G4EUV7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_022115</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000215">
        <property type="protein sequence ID" value="PHX53323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53323">
        <property type="protein sequence ID" value="PHX53323"/>
        <property type="gene ID" value="CP500_022115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="368"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="376"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="537" mass="57895" checksum="2EA7F0DF66BBE136" modified="2018-01-31" version="1">MQPPIAIGTILQNRYRLLNILGQGGFGRTYLVEDLGRFQERCALKEFIPVQSGPYVLEKSKELFQREAAILYQIQHPQIPQFRAMFEEGQRLFLVQDYVEGMTYRELLLDRASTGRTFNETEVLVFIRQMLPVLAHIHARGIIHRDISPENIIRRENDQMPVLIDFGVVKELATKVQSPEGTVHATTVGKIGYAPIEQLQSGRATASSDLYALAVTAIVLLTGKEPQELLDQTTLLWNWQQKVQVSTDFALVLNRMLNRSPVDRYQSVSEVAQALDGQINPYANPQSVAPTQPPMSSNVSQVATVAVGRRPDAIAQSSHPQNQPDPVIKPGSDSLWDNPMAAIGLGAGLVILTGFGSWALVGSFLNKGSQPTQTPPALTSPTPEPLPTRTPEPLPTPTPEPLATPTPEPIPEPSPEPSPEPSPEPSPEPSPEPSPEPIPEPSPEPIPEPSPTPTPEPKPTPAPTPTPKPTPTPTPPPKPTPAPKPTPAPTPAPTPAPVENPAPTPAPVENPVPTPAPVENPTPSPAPVENPTPSPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV10</accession>
    <name>A0A2G4EV10_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin reductase</fullName>
            <ecNumber evidence="3">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">trxB</name>
        <name evidence="6" type="ORF">CP500_021785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000205">
        <property type="protein sequence ID" value="PHX53382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53382">
        <property type="protein sequence ID" value="PHX53382"/>
        <property type="gene ID" value="CP500_021785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="337"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="454" mass="49505" checksum="178D39D1B1E8FE16" modified="2018-01-31" version="1">MTNETVENLVIIGSGPAGYTAAIYAGRANLKPIVFEGYQMGGIPGGQLMTTTEVENFPGFPEGITGPQLMDRMKAQAVRWGAELYTEDVISVDLSQRPFIVRSEDREIKTHTIVIATGATAKRLHLPSEEKYWNLGISACAICDGATPIFKNVELAVVGGGDTAAEEGVYLTKYGSRVHMLVRSSSMRASKAMQDRVLNNPKITVHWNTEPVDVYGNGKLAGIQVRNTQTGAESSLPVSGLFYAIGHTPNTVLFQGQLELDQIGYIAPKHGSVETSVEGVYAVGDVQDHEFRQAITAAGSGCMGAMLAERWLSANGLTQEFHQTEESEKPAAVAETPKVRETSENFDIKETRHEGGYALRKLFHDSDRLIVVKYSSPTCGPCHSLKPILNKVVDEFDGKIHYVEIDIEEDPEIAENAGVIGTPTIQYFKDKALVTELKGVKPKSQYRELIASNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV39</accession>
    <name>A0A2G4EV39_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Precorrin-8X methylmutase</fullName>
            <ecNumber evidence="6">5.4.99.61</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_021680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CobH/CbiC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.61" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53412">
        <property type="protein sequence ID" value="PHX53412"/>
        <property type="gene ID" value="CP500_021680"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016993">
        <property type="term" value="F:precorrin-8X methylmutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003722">
        <property type="entry name" value="Cbl_synth_CobH/CbiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036588">
        <property type="entry name" value="CobH/CbiC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02570">
        <property type="entry name" value="CbiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63965">
        <property type="entry name" value="SSF63965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiC" evidence="5">
        <location>
            <begin position="8"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="207" mass="22313" checksum="EEC080F6670A1E81" modified="2018-01-31" version="1">MEWHVSDAQSLGLIDSEIGDHGFSAAEYEIVRRVIYATADFEYKSLISFSDQALQAGAAALAARTTIVVDVPMVQVGITPLIQSTFANPVYCSMEALTRPQKERTRAAWGIETLAKRYPEGIFVVGQAQTALSAIVDLIEAEEIRPALVIGTPSGFVGGDVAKSRLHDSMIPHIRIEGRKGSAVVAVAIVNGLVDLAWQAYGQERNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVC2</accession>
    <name>A0A2G4EVC2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000192">
        <property type="protein sequence ID" value="PHX53479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53479">
        <property type="protein sequence ID" value="PHX53479"/>
        <property type="gene ID" value="CP500_021310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="319" mass="36184" checksum="08AC8A450943356D" modified="2018-01-31" version="1">MPKISVCIPTCNRVHLLAGAIASVLAQSYTDFELIVCDDGSTDSTPLLMSEFVGDGIRYIRHSQNIGKSNNMRSGFAAARGKYFIKFDDDDRLTPQFLERTSAILDKNDSIDFVSTDHWVIDINNQIDESLTKLNSHRWGRTELSAGIIQDLLTTVFVQQSLQIGATLFRRSVLEEVGFLRPNWQNCEDNDLFVRLAIAGKKCYYLPELLMEYRFHVQQQGCDRAIPYLTDKLRYLTGYEFDAEKLESVRLRRIAETQLALGLRLIEVGETQKGRWMVRAGKSVSEAKMWAGLGLSLLPMKLRGRAFAVVRDLVNSAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVD8</accession>
    <name>A0A2G4EVD8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Prephenate dehydratase</fullName>
            <shortName evidence="9">PDT</shortName>
            <ecNumber evidence="3 9">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pheA</name>
        <name evidence="12" type="ORF">CP500_021240</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="3 9"/>
    <dbReference type="EMBL" id="NXIB02000190">
        <property type="protein sequence ID" value="PHX53494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53494">
        <property type="protein sequence ID" value="PHX53494"/>
        <property type="gene ID" value="CP500_021240"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00857">
        <property type="entry name" value="PREPHENATE_DEHYDR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00858">
        <property type="entry name" value="PREPHENATE_DEHYDR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 9" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="10">
        <location>
            <begin position="4"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="11">
        <location>
            <begin position="227"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="site" description="Essential for prephenate dehydratase activity" evidence="8">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001500-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="307" mass="33469" checksum="F21F16C67646A151" modified="2018-01-31" version="1">MKISIAHLGPVGTNAETAALAYVQWLSKETNSECTLCPYSTISQALEASATGLVDLSVVPVENSIEGSVTVTLDTLWKLDRLRIQHALVLPISHALISKAKSFNEIQKVYSHPQALAQCQLWLGQFIPSAVLIPANSTTESLDYIDDTSVAVISAPRAAQLYNLPVLAHPINDYPDNYTRFWILGKGVEELENVEIGDRPSSIKSITKSATKLILDASSSNCTHTSLAFSVPANMPGALVKPLQVFASRGINLSRIESRPTKRSLGEYIFFMDVEANACQALVRSALEELKLYTETLKIFGCYSVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVF6</accession>
    <name>A0A2G4EVF6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dacB</name>
        <name evidence="2" type="ORF">CP500_021110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000186">
        <property type="protein sequence ID" value="PHX53514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53514">
        <property type="protein sequence ID" value="PHX53514"/>
        <property type="gene ID" value="CP500_021110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000667">
        <property type="entry name" value="Peptidase_S13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30023">
        <property type="entry name" value="PTHR30023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02113">
        <property type="entry name" value="Peptidase_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00922">
        <property type="entry name" value="DADACBPTASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00666">
        <property type="entry name" value="PBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="470" mass="51116" checksum="E14722DD30C05E73" modified="2018-01-31" version="1">MLLSHSSAVFAQIPAVSGDICAVDLGAKIDAIANRAEFSRSRWGILIQPLSSPTTLYSRDSQKYFIPASNVKLLTTAAALQKLGGDFRIKTSVYSGENGNLHIVGRGDPSIAEAQLKSLAQQLKQRGISRVNELIGDDSYFQGNPVNPNWEWEDAQAGYGAPINSLIFNQNAIELILSPQAIGQPLKVTFAQPKPINQWQIQNNSVTVGQNKSEFVEVGREFDKPILRVSGQLRVGAESESAYVAVVNPANNFLQHFQQVLAGEGIPVKQALVASNFRNFSQELANIESPPLAELVKETNRESNNVYAEVLLRLLGKETGKMPVSQEQDTMEIGLKELKTTLTQLGINPNTYKLADGSGLSRHNLISPEALVQTLRLMANSPLASIYRASLPVAGESGTLKNRFLTPNRVILQAKTGTLSGVAALSGYVEVPNYEPLVFSIMVNQSDLSAPKVRSAIDEIVLLLNRLSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVJ9</accession>
    <name>A0A2G4EVJ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M23 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000177">
        <property type="protein sequence ID" value="PHX53561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53561">
        <property type="protein sequence ID" value="PHX53561"/>
        <property type="gene ID" value="CP500_020825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013868554" evidence="1">
        <location>
            <begin position="34"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="185"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="292" mass="31217" checksum="F7CC1A8E6ECD79E9" modified="2018-01-31" version="1">MLGCRLLRTNMKRATLSGGIVASILCLVSPVQALQVVVTPANPELGDTLSVMIQVDGSGETPTVSVQQKKYPAFPMGNNRFRALLPTTPVEKPGAREIQVAGDGQVQKLSVQVRSRNFPTQSITLPPGKDGEGSDAEFDRVDAFKALVTPQKFWNGPLLRPNSGEITTIYGVRRYYNGVFAQDYYHRGVDYAGAYGSPVIAPAAGRISLVGRESQGFTIHGNVVGIDHGQGVASILMHLSRIDVKEGDFVQAGQVIGGLGSTGASTGPHLHWGLYVNGQAIDPVPWRLQGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVL1</accession>
    <name>A0A2G4EVL1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Low-complexity protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53569">
        <property type="protein sequence ID" value="PHX53569"/>
        <property type="gene ID" value="CP500_020725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="430" mass="46532" checksum="46D8206D6586B028" modified="2018-01-31" version="1">MTPEPNSSQPNPSPAIATAESLNGTAPKVPTEPATIVSTAEPEKSVPQASTRKIVLPEYPKQTAAEMLGSVLILGSVAVMIIGLANDSVWLGLMGAIAAMGISLRLMWPSWGKIWVQVIPPAWRTLIVACFGLLAGIVGLLMLSGTNTERGSHNIQINWDAIGALGELIGALGQILIAILGVYVAWRQYVISKDLTIQQNRITQQQTIDAYFQGVSDLALDEQGFLEDWPQERAIAEGRTAAIMSSVDAEGKAKILRFLSQSRLVTPLKRDRLLGRAILDGDGGYAEDRDHGIRVIDLNVMLAGADLASTDLRWTDLSEANLVRADLSKCDLVKANLSRTVLYDANLVRADMKGTTLFYGSVETASPRSRSEFPNYTTGEYTGAVVERVDFTGVKRLSEEQRKYCCAWCGSKSRDTIPGGCEGIPNKLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVP7</accession>
    <name>A0A2G4EVP7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DedA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_020595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DedA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000173">
        <property type="protein sequence ID" value="PHX53611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53611">
        <property type="protein sequence ID" value="PHX53611"/>
        <property type="gene ID" value="CP500_020595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032818">
        <property type="entry name" value="DedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30353">
        <property type="entry name" value="PTHR30353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="207" mass="22814" checksum="6866CAE1332442B3" modified="2018-01-31" version="1">MSFEFLSLETIQQFAHDYGYWAIFLGILLENLGIPLPGETITIAGGFLAGSGELNYWFVLASAIAGATVGGNFGYAIGRYGGWPLLLKLGKIFRFREEQLFDLKEKFSENAAKAVFLGRFIALLRIFASPLAGIAEMPFWKFSLFNILGAASWASVMVSLSYFLGQVVSLEKLVAWAAQFAVVALLLAVAWIAIPIWLESRNLDKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVU4</accession>
    <name>A0A2G4EVU4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylate/guanylate cyclase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000168">
        <property type="protein sequence ID" value="PHX53639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53639">
        <property type="protein sequence ID" value="PHX53639"/>
        <property type="gene ID" value="CP500_020375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="205" mass="22814" checksum="B762D83CE6F45316" modified="2018-01-31" version="1">MKTNNRACLEKLLQERNERPEKMAEIDAQINATFRQSHVIMVIDMSGFSRTTVRHGIIHCLAMIHRMHAIVYPVIAECGGTVVKEEADNIFAVFPDVKSAVQAAIDSLKHTGAVNTTLPPEMDIYLCIGIGCGDVLMLEGEDMYGSEFNLASKLGEDLAEQGEILLTNSAFEKFEGKKEDWEKVEFSISGLELVAYKRVIYSSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVX2</accession>
    <name>A0A2G4EVX2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">trpD</name>
        <name evidence="8" type="ORF">CP500_022080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate</text>
            <dbReference type="Rhea" id="RHEA:11768"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 2 magnesium ions per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000213">
        <property type="protein sequence ID" value="PHX53327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53327">
        <property type="protein sequence ID" value="PHX53327"/>
        <property type="gene ID" value="CP500_022080"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 5 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="7">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="6">
        <location>
            <begin position="83"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="92"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="99"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="117"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="347" mass="36085" checksum="500BF9BAE5B4A3A8" modified="2018-01-31" version="1">MTDSPQWPSLLQQLLDRQSLDRTTAANLMQGWLSEAIPPVLSGAILAALQAKGISAPELAGMAQVLQSQSLTGESQSIVPNLKLIDTCGTGGDGASTFNISTAVAFVAAAGKVRVAKHGNRSASSKVGSADVLEALGVNLNADSERVRAAVDSVGITFLFAPGWHPALKAVASLRRTLKVRTIFNLLGPLVNPMRPTGQVIGVFDPSLVSTIAEALGELGTELAVVIHGREKLDEAGLGDVSDLAVLSNGKVEVTTLDATKVGLTHCAIDSLKGGNVEENSEILRNVLQGKGTRAQMDVVALNASLAFQVGGVIPLGAHEAGVVLAKEILLSGEAWLKLEELVEFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVX6</accession>
    <name>A0A2G4EVX6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Chorismate synthase</fullName>
            <shortName evidence="8">CS</shortName>
            <ecNumber evidence="4 8 9">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroC</name>
        <name evidence="10" type="ORF">CP500_020565</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8 9">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8 9"/>
    <dbReference type="EMBL" id="NXIB02000173">
        <property type="protein sequence ID" value="PHX53606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53606">
        <property type="protein sequence ID" value="PHX53606"/>
        <property type="gene ID" value="CP500_020565"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8 9" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="124"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="301"/>
            <end position="305"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="366" mass="39482" checksum="725933E11C1A42CE" modified="2018-01-31" version="1">MGNTFGHLFRISTFGESHGGGVGVVIDGCPPLLSIDPSEIQAELDRRRPGQSKITTPRKEADTCEILSGVFEGKTLGTPIAILVRNQDTRSQDYDEMATTYRPSHADATYDAKYGIRNWQGGGRSSARETIGRVAAGAIAKKILKQVAGVEIVGYVKRIKDLECFADPDTVTLEQVESNIVRCPDAECAERMIELIEKVRDSGDSIGGVVECVARNVPKGLGMPVFDKLEADLAKAVMSLPASKGFEIGSGFAGTLLTGSQHNDEYYTDEQGTIRTVTNRSGGIQGGIANGENVILRAAFKPTATIRQQQRTVTREGEETLLAAKGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHGQCGTLKSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVX7</accession>
    <name>A0A2G4EVX7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000169">
        <property type="protein sequence ID" value="PHX53638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53638">
        <property type="protein sequence ID" value="PHX53638"/>
        <property type="gene ID" value="CP500_020445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="187" mass="21255" checksum="E03C2B86DFD66036" modified="2018-01-31" version="1">MVQTTLKSLTLEEFLQLPETKPASEYIDRQIIQKPMPQGKHSITQCELIIFINSILKLKKVARAFPELRCTFGGRSTLPDVSVFVWNRIPTDDNGEIANVFTIAPDWTIEILSPDQSQTKVTKNILHCLNHQTQMGWLIDPDEQCVFVYLPQQQTVVFDEPEMLLPVPSFASELQLSVGALFGWLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW26</accession>
    <name>A0A2G4EW26_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RRXRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000165">
        <property type="protein sequence ID" value="PHX53666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53666">
        <property type="protein sequence ID" value="PHX53666"/>
        <property type="gene ID" value="CP500_020280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025938">
        <property type="entry name" value="RRXRR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14239">
        <property type="entry name" value="RRXRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRXRR" evidence="2">
        <location>
            <begin position="4"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="339" mass="38253" checksum="ED14DF7F96F86B8D" modified="2018-01-31" version="1">MQFVPVVDSNQRPLMPTTPKRAQRWISSGKATPFFRKGIFCVRLNVEPLSRHLQPVAVGIDPGSKREGYTVKSKAHTYLNQQFHAVDWVKDAEKTSTNARRARRNRKTPYRPNRQNRKRGGIPPSTKARWQLKIRVVKVFAAIFPISSIGIEDVKAIAKKSSPKWNTSFSPLEVGKKWCYSELERIAPVTEFDGYTDTYLTRQKLGLKKSKAKLSNGFNAHCVDAWVLAYLLVGGALSPENMVVMECKPIRIYRRQLHVFNPGPSGYRRPYGGSMSQGLKRGGIVKHPKYGSCYVGGEDAKKSRISLHSLGTGKRLCQNAKPTDCKFLAYNSWRTVKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW46</accession>
    <name>A0A2G4EW46_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mannose-1-phosphate guanylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000158">
        <property type="protein sequence ID" value="PHX53741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53741">
        <property type="protein sequence ID" value="PHX53741"/>
        <property type="gene ID" value="CP500_019850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_I" evidence="3">
        <location>
            <begin position="384"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="4">
        <location>
            <begin position="535"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="5">
        <location>
            <begin position="637"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="847" mass="93093" checksum="7C9249310DD66E3F" modified="2018-01-31" version="1">MRAVLMAGGSGTRLRPLTCDLPKPMVPILNRPIAQHIINLLKRHHITEIIATLHYLPDVMREYFGDGSEFGVQMTYAVEEDQPLGTAGCVKNIAELLDRTFVVISGDSITDFDLTAAIQFHRSQRSKATLILTRVPNPMEFGVVITGENHRINRFLEKPSSSEIFSDTINTGIYILEPEVLDYLPIAQECDFSKDLFPLLLEKGEPMYGYIANGYWCDVGQLDVYREAQYDALRGKVKLDLDYYDQVRSGFWVGQNTSIDDSAIVEMPVMIGNNCRIGARVKIQAGSVIGDNVTIGADANVKRPIVWNGAIIGEDAHLRACVICRSTRVDRRAHVLEGAVVGSMSIVGEEAQVGPSVRVWPSKSIESGALLNQNLIWGEQAKRNLFGQRGVQGLANVDITPEFAVKLGAAYGSTLKPGASVSVSRDQRSISRMVSRSLIAGLMSVGISVVNLESTAIPIARSVSSTLSVTGGIHVRISPDRSDHILIEFFDSKGINITKAAEKKIEGAYFKEDLRRALIPEIGEMSYFNQSLDVYSHTFERQMNVEAIRYSNSKVVIDYVYAVSGAFLPQILAKFGCDAVVLNASLKQSSLSNGEREYLLDQLGRVVKALSANFGVQVSANGEQLILVDESGIAIRGEMLTALMVNLMLTSHPKGTVVVPVNASSAVEAIARRYQSKVIRTKANPSALMEAANRNPNVVLGGSGNMGFIFPQLHPGFDGMFCIAKVIEMMTIQERSLGQIKAELPRVTHRSYSVRCPWTVKGSLMRYLVETHSPDSLELVDGVKIFNSSDDNWVLVLPDASEPTVHIFANSEDRDWVSETLKEYRTLVHDFVGNTEAAVRQDKFGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW75</accession>
    <name>A0A2G4EW75_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_019715</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53779">
        <property type="protein sequence ID" value="PHX53779"/>
        <property type="gene ID" value="CP500_019715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="236"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="428" mass="46113" checksum="2199FE5A6AF1B2D4" modified="2018-01-31" version="1">MHPASPPPDRNGLNALFRNRAFLALWTGQLLAQVADKIFYVLLIILLKTGDYTPGQNFQNSMLSAVMIAYTVPAIVFGSVAGIAVDRFPKKQMLMGCNVIRALLIVAMAFLPKAFVVLLVITFLVSTVTQFFAPAEAAAIPLAVGREGLMSANALFASSTMGGIIVGMTIGEPLFTWIKHSYGGGSREFLLAGLYVISAVLIYAMRIKETHAGSSAKNIHPWQDFKEGLRYLKHNRLVSNAMVQLTILYSVFAALQVLAIALSGKIGLKETQFGFLLAAAGIGMVFGAAFLGHWGDRVYNKPLPLIGFLMMGFVLAMFAFTRQLWLGFSLSALFGFGASLINGPMQALIQEQTPESMRGKVFGFENNAINIALSLPLAITGPLTDAVGKAVGSDDLGLRIVLLSLGCLVPVMGLVAWRHTRNVLQDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWA0</accession>
    <name>A0A2G4EWA0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purA</name>
        <name evidence="11" type="ORF">CP500_019945</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53736">
        <property type="protein sequence ID" value="PHX53736"/>
        <property type="gene ID" value="CP500_019945"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="298"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="330"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="412"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="442" mass="48530" checksum="3FB441C590E6AF75" modified="2018-01-31" version="1">MANVVVIGAQWGDEGKGKITDLLSKSADIVVRYQGGVNAGHTVVVDGQTFKLHLIPSGILYPETECIIGCGTVIDPKVLIQELDQLETLNVSTAKLMISQTAHITMPYHRLIDVASEEQRGNYKIGTTGRGIGPTYADKSERTGIRMLDLMDLEGFREQLEWTINYKNVILEKLYNLPPLNPQDVIDEYHVYAERLRPHVVDSSLKIYEGIHKRKNILFEGAQGTLLDLDHGTYPYVTSSSPIAGGACVGTGVGPTAIDRVIGVAKAYTTRVGEGPFPTEMVDGIGAVLGERGAEFGTTTGRKRRCGWFDAVIGRYAVRINGLDCLAVTKLDILDELEEIKVCVAYEIDGERCIDFPKNSRIFARCKPIYETLPGWKQSTEECRNLEDLPQQALDYLKFLADLMEVPIAIVSLGAGRDQTIIVEDPIHGPKRGLLSVDGTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWD0</accession>
    <name>A0A2G4EWD0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipopolysaccharide biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021275</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000191">
        <property type="protein sequence ID" value="PHX53487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53487">
        <property type="protein sequence ID" value="PHX53487"/>
        <property type="gene ID" value="CP500_021275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="CbiA" evidence="4">
        <location>
            <begin position="516"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="724"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="322"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="743" mass="81887" checksum="94327087E3873864" modified="2018-01-31" version="1">MTLSVVKRYLIAFDQYKWVGLATLAVSVGVSGVVAVQPTPRPVYVAAGMLTYRRPAVIFSSTTTKIQQEGQEITKDMLLDKKVIEAAAAKVKVSAKKLADDVQVKMPSKNNDPSALIQVLYKNADRKKAEIVVEALMKEMVARSQTINTSRLRETIAQINQRLPKVTQELRETEEKLETYEKREGTSILAAQSGSLPQAITGSEQQQRQLRVQLGGIEAQINSLQNRLGLNVEQAYVAQALSADPIIGQLRVQIFSLESQLKILRSDLQEEHPKIVELLKQKQAFDQQLQQRQSEVLGGNGVAAPLRSADRIRIDSSLDPSRQLLAQNLIALQTQKEVVEQQIKGVEKTEQELRRQHATIPNKQLEQARLAQQVGFKKALYDKMQSALVDAEASVAETTGSLTIAQPPKTDDVESSKRGLPVMLAVGGFVGLLLGGGLIFLLGMLNGKFYSWEEVRAALVEKEVPILGLLPEVSILDSYGLEMPIALDINSPYLEFYERLRTNLRRIGGKPVKVVLLTSAASEEGKTFSAYNLAIASARSGKRTLLIEADLRSASHIESLKIAIDPLAAVEPLHYYGNISECVRLVPDVENLYVVPSPGCLHRAAGILESSEMRRLFEDVRNRFDFVVVDSPALSECNDALTLEPYTDGIILVARPGYTLSSMLSEAADQLLESDDEESSKSPRLLGAIINGADIAVKLRHDIQEVEMPLSAIRDGAIEVRSHQLPQQQSKLKNKAINSKYIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWF1</accession>
    <name>A0A2G4EWF1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carbohydrate ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019670</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53770">
        <property type="protein sequence ID" value="PHX53770"/>
        <property type="gene ID" value="CP500_019670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="101"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="305" mass="34140" checksum="D232EB5323BF2EBD" modified="2018-01-31" version="1">MDNKASREARTYNHIPIMNNIKTKKPNSPNATPSLWKTLWIYGMMSAIGLLMLFPLLWLLSTSLKSPTENIFQFPPQLWPQQPTLQNFIKVWQTNPFGRYLFNSTLIATLTVSINVLFCALAAYPLARINFRGREAILIIIISTIMIPFQIVMIPLYVLTVQLGLKNSYLGVIFPGLASAFGIFLLRQAFLAVPKELEEAARIDGCSELGIWWHIMIPAIKPALVTLGIFVFIGSWSDFLWPLLVLDRPEYYTLPLGVANLAGTFSLDWRLVAAGSIISIVPVLGLFLILQKYIVPTETATGVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWH1</accession>
    <name>A0A2G4EWH1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_019160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000146">
        <property type="protein sequence ID" value="PHX53869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53869">
        <property type="protein sequence ID" value="PHX53869"/>
        <property type="gene ID" value="CP500_019160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="157"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="453"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="532"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="581"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="717"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="799"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="852"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="931"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="1137"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1295"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1094"/>
            <end position="1121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1410" mass="158999" checksum="CD82642C47DF1D2C" modified="2018-01-31" version="1">MQEVVNWYQSFLSNSVDAFLECDRQQKYLYVNSIAAEWMGLEPSEIVHRTNQDLLKLYPNNPALKNIISQIDSCLQQVLLTGERRLAIHEVIEVDGGIKIYETAYTPVVDVSSNQMRVFGVGRDITRHYRWQQQKTQQLRRSNHLLWLNAANTPLAMLGWDENFRIIQWSKRAEEIFGWTSDDMMGKRFDDLALVCPEDREAVSAIELELATGKGNTSINRNYTKSGTVIWCRWFNSIIRSGDTFTVLSLVEDITDRKILEAAKAQGTRLTAMVADVGIALTKYPQDILMPCCEAIVKNLDVVSAEIWTFNSQEKALEMQAVAERSSRQDNIAHFVQTKINEIAQSQKPQTDCIFQLNNVNIFTQNLGENIVGNSWELAVSENPNIGVNCSVQKPIVSFSGYPLIVEERLVGVMGIVSTQPMTEAFQETISSVADVIALGIERKRAEAELKSARAFLTSVVENLPVGVFAKDASSLKFVLWNKAGETIAGVTSQEAIGKNDYDIYSKEQADVSTAQDREFLTRYQNQSRLTEILEEPFQTRHKGMRILHTRKVPILDSKGNPQYVLGITEDITERRQVDESVRLYDQIVENMQIGLYVYHLENMDDDSTLRAIASNPAATKFTGLEMADVLGMTIDEIFPKSRSKNIPQVFSSVIRNQKAVELEDIDCDESGRITRTLSIKAFPLPNNCIGVAFENITDRKCLELDLKLALEQTERSEQLLRTVIDKSSDWIFAKDQDFRCILANNSFAQALGKRVEEIIGKSDLELMIYEDIIVENATENILKLRTDDLAVLAGGIIHNPCDSAVFADGSIHIFDTQKVPLRDTEGHIFAVLSFAHDITERHKYEAALRRSEARFRSLVANIPGVVYRWQCDFSPTFISDAVYSLTGYPAADFRLLSNRGGRSFASVIYSEDLAQVEATIRQGIENKQSYSLEYRLVAADGTIKWVWDKGSPVFDEDGKVDCLDGVIFDISDRYHAQEALQQKTSELEAVFRTLPDLYFRLNADGVILDYLSGDSSDIYMATEDFLGKRMLDIFPANIASKFEKAIFQALEKNTSVTLEYSIEISNKKETYEARLLPFNASQIIIISRNITLRKQAESKLKEKNYELKQALKQLGRTQSQLIQSEKMSGLGQLVAGIAHEINNPISFIYGNVAYASEYAENLLKLCCVYQEHYPEPVSVIADLAEEIEIEFMKEDFPHLLNSIKIGAERIRQIVLSLRNFSRLEESDIKRVDIHEGIDSALLILEHRIKENGRIRNIEIVKEYGELPPVQCYVGQLNQVFMNILSNAIDALGTVRNRKPEPGTSETEREDSSGLSVSCNASHWILIRTEVLENNRIAIAISDNGPGMEESVKSRIFDPFFTTKPVGKGTGLGLSISYQIVVERHGGTLRCVSTPGRGTEFAIEIPIRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWP5</accession>
    <name>A0A2G4EWP5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53954">
        <property type="protein sequence ID" value="PHX53954"/>
        <property type="gene ID" value="CP500_018685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="83"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="263" mass="30720" checksum="B7B99150DB729C9C" modified="2018-01-31" version="1">MFVATKNSETKLTITWPLLPEDFQLPDDPVEDESQPLLAAALRQPLTEFPELIQDALIVSNFALCAGISFPEAATDEQRTICKAPDWMYVKPVNPKNVSQIRRSYTPHTEGIIPQIVMEFLSETYGEEYSVEFTSRVGKWFFYEQVIKVPRYVIFRAKTAHLEVHALESEHYNRQKADENGRYWIPGLDLFLGMWEGTHEGRTGCWLRWWNAAGELLLWSEERTEQERQRTELERQRADREKLRAEKLAEKLRQAGIELDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWP6</accession>
    <name>A0A2G4EWP6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">glyA</name>
        <name evidence="10" type="ORF">CP500_019225</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000148">
        <property type="protein sequence ID" value="PHX53860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53860">
        <property type="protein sequence ID" value="PHX53860"/>
        <property type="gene ID" value="CP500_019225"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="9"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="126"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="355"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="427" mass="46041" checksum="F54C67266DC84926" modified="2018-01-31" version="1">MTDSNLEFLAKTDPLISDLIGQELQRQRDHLELIASENFTSAAVMAAQGSVLTNKYAEGLPGKRYYGGCEFIDGIEQIAIDRAKQLFGAAHANVQPHSGAQANFAVFLSLLQPGDGIMGMDLSHGGHLTHGSPVNVSGKWFKASHYGVSKETEQLDYDDILKQAKENRPKLLICGYSAYSRIINFEKFRAIADEIGAYLLADIAHIAGLVATGHHPNPLPYCHAVTTTTHKTLRGPRGGLILTNDLELGKKFDKAVFPGSQGGPLEHVIAGKAVAFGEALKPEFKTYSGQVIQNARALAAQLQQRGLKLVSDGTDNHLMLVDLRSVNMTGKLADQLVSGVNITANKNTVPFDPASPFVTSGLRLGSAAMTTRGMGTTEFTEIGNIIADRLLNPEDESVATECKHRVAALCSRFPLYPHLFLKVPALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWS6</accession>
    <name>A0A2G4EWS6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_019035</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000143">
        <property type="protein sequence ID" value="PHX53890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53890">
        <property type="protein sequence ID" value="PHX53890"/>
        <property type="gene ID" value="CP500_019035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="27"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="354"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="387"/>
            <end position="394"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="593" mass="65839" checksum="F2372C420BEFB52C" modified="2018-01-31" version="1">MSPNSPKSTHPLQRLLKYGRRYRLQTWLATISSFLNKLFDLAPPALIGIAVDVVVKHEDSIIAQWGVKDVFWQLAIITLLSAIVWALESIFEYAYDYLWRNLAQNIQHDLRLEVYSHLQELELAYFEERSTGGLISILNDDINQLERFLDGGANDVIQVITTVIIIGAAFFAASPTVAVLSMLPIPFIVWGSIAFQNRLAPLYADVREKVSFLNGQLLNNLSGITTIKSFTSEDYETQRIETQSEAYRQSNRKAIVLSAAFIPLIRILIFLGFIATLFLGGLEVVAGSLSVGTYSVLVFLTQRLLWPLTRLGDTLDQYQRAMASTNRAMDLLDTPIAIRTGDIRLPISSIKGALEFKNVTFSYHQRRPILQNFSLTLMAGKTTGIVGPTGSGKSTLVKLILRLYEVQYGQITLDGIELTKLNLKDLRGAIGLVSQDVFLFHGTVAENIAYGSFDATNSEIIDAAKIAEAHEFIAQLPDGYETIVGERGQKLSGGQRQRIAIARAVLKNPPILILDEATSAVDNETEAAIGRSLERITQNRTTIAIAHRLSTVRNADCIFVMDEGRVVESGQHEQLLEHDGVYASLWRVQSGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX08</accession>
    <name>A0A2G4EX08_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP-sulfurylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Sulfate adenylate transferase</fullName>
            <shortName evidence="7">SAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">sat</name>
        <name evidence="10" type="ORF">CP500_018160</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H(+) + sulfate = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000128">
        <property type="protein sequence ID" value="PHX54061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54061">
        <property type="protein sequence ID" value="PHX54061"/>
        <property type="gene ID" value="CP500_018160"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00204"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00517">
        <property type="entry name" value="ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00066">
        <property type="entry name" value="Sulf_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020792">
        <property type="entry name" value="SO4_adenylyltransferase_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002650">
        <property type="entry name" value="Sulphate_adenylyltransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00339">
        <property type="entry name" value="sopT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA_2" evidence="9">
        <location>
            <begin position="8"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-sulfurylase" evidence="8">
        <location>
            <begin position="174"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="393" mass="44588" checksum="D077B36B9910A72F" modified="2018-01-31" version="1">MSQHPDRIAPHGGILVNRIATLDQRQEFFDKAEALPRVQLCDRSISDLQMIAIGAFSPLEGFMDEADYRSVVKEMRLSNGLPWSVPITLSVTEEVASPLTEGTLVRLDSPNGEFAGILQLTEKYRYSKEEEAINVYRTDDLKHPGVQVLDKSGPINLAGPVWLLERELDPRFPQYQIDPVKSRMLFAEKGWKTIVGFQTRNPIHRAHEYIQKCALETVDGLFLHPLVGTTKDDDIPADVRMRCYEILLEKYYPHDRVILAINPAAMRYAGPREAIFHALIRKNYGCTHFIVGRDHAGVGDYYGTYDAQYIFEEFEPGELGIVPMKFEHAFYCKVTEQMATTKTSPSTPEQRVHLSGTKVREMLRAGKLPPPQFSRPEVAAELAKAMNIFSYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXC7</accession>
    <name>A0A2G4EXC7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SagB-type dehydrogenase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000117">
        <property type="protein sequence ID" value="PHX54181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54181">
        <property type="protein sequence ID" value="PHX54181"/>
        <property type="gene ID" value="CP500_017505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020051">
        <property type="entry name" value="SagB-type_dehydrogenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03605">
        <property type="entry name" value="antibiot_sagB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="98"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="331"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="512" mass="58141" checksum="8DF464BA92BBB8BD" modified="2018-01-31" version="1">MPETPVSIAQHYHERTKYDPQTIAAKSRQLDWEKQPVPFKEYKIGAYFDLKPYLKDTSEESQTEPDGSWWHRLSNFLLCSYGLTAKVSMMDGNPLYLRAAPSAGGLYPAEVYLISRGTEYLPAGLYNYQARTHSLVHFWDSEVWPALQAACFWSPALEETKLALAITNVFFRSSWRYEDRAYRRIFLDTGHLLSNIELASALNDYRPHLIGGFADEAVNQLLYIDSKQEGAICVVALADLLDIKQNLPKFRTALPGNTTTDYPKIPEGQLLEYLHESTQLESDTTGADGWKINDKEGGIEDKYNFPFCTKVSTVTPSISWGFHLDNLENTILKRRSTRYYTGASLKLDELLALLDFTYQPHHYIDQGLDSDPDYFDLSLIETFVAVSGVNGLEEGCYYYAPKAQELRQIRFKNFRRELHYLCLGQELGRDAGVLLFHTADLKQAVAKYGDRVYRYLHMDAGHLGQRLNLAAIQLRLGVSGIAGFFDDKVNEVLGIPADEAVLYITTLGRPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXF8</accession>
    <name>A0A2G4EXF8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54224">
        <property type="protein sequence ID" value="PHX54224"/>
        <property type="gene ID" value="CP500_017310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="9959" checksum="2889E3AF1F6BF890" modified="2018-01-31" version="1">MTATLISDVLQDDIAVAIARAIAAANKRARELNIDVMQSIISLTQHPQNDSWVWRVNYGAKDYIGRRGGDLIIEVNPEDISIQRVLWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXJ4</accession>
    <name>A0A2G4EXJ4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsO</name>
        <name evidence="3" type="synonym">rps15</name>
        <name evidence="8" type="ORF">CP500_019115</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="3 6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000145">
        <property type="protein sequence ID" value="PHX53877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53877">
        <property type="protein sequence ID" value="PHX53877"/>
        <property type="gene ID" value="CP500_019115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10308" checksum="18D8569F3DF19ABE" modified="2018-01-31" version="1">MALTQERKQEIMGDYQTHETDTGSPDVQVAMLTDRISKLSAHLKINQKDFASRRGLMMMISRRKRLLAYLQKENVDRYKALIARLGIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXK9</accession>
    <name>A0A2G4EXK9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_017075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54282">
        <property type="protein sequence ID" value="PHX54282"/>
        <property type="gene ID" value="CP500_017075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="144"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="433" mass="48142" checksum="86BF3D94DB532DB2" modified="2018-01-31" version="1">MSQLIHNQKINRLPILKIVKAIALILLRILVFIAIALAILPVALLPISTTVPASIQILFAMAEVALLIAVFRLGFTGRVIFSELAGFMAIALLAIFASQLFASTPPILDVNGKPIPNSIAVLEKVKLGGSEEWISIRGKDSRNPVLLFLAGGPGGSQLVLEQRALAGLEDRFVVVNWDQPGAGKSFNAIDHAKLTPDRYITDTRELVLNLRQRFGKDKIYLSGQSWGSALGIMVVQRYPELFHAFIGTGQVVAFLENEVIKYDLALRLARVRGDQQQGSKLKQQGPPPYYGNDVLPKMLTYLNDLKKYRNDDQNLAIAKPKSNIVFDLITSSEYGLYDKVNLSRGELETVGVVFPQLWGVDFRKQATRLKVPAYFLIGRHDGTTSPKLTEEYFNLLTAPHKELIWFERSGHGPWMNEPAKFVDVMVNKVLAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXW5</accession>
    <name>A0A2G4EXW5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54326">
        <property type="protein sequence ID" value="PHX54326"/>
        <property type="gene ID" value="CP500_016765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013922128" evidence="1">
        <location>
            <begin position="28"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="12952" checksum="7D1D471C4476C8F5" modified="2018-01-31" version="1">MTKMTARQIIIAIVAIPIALMTQTASFAISTTTNVSPIKQVLPGEDEIDFDNLPSQSISIEESEDWDNSNFLADFDMLKTEIMESGVRPEITSPPPKLYISAARGRSSRSCRISGICE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXZ9</accession>
    <name>A0A2G4EXZ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54399">
        <property type="protein sequence ID" value="PHX54399"/>
        <property type="gene ID" value="CP500_016275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="216" mass="25114" checksum="08EE8A3E2E23C9AE" modified="2018-01-31" version="1">MQTQEKPAIAKQPPTEKRYYTPEEYLALEESAIDKSEYHDGEIVPMTGGTANHNKIAGNFYKKFPSTVNGQDYETFINDVRLWIPLTRRYVYPDIMVIQGEPKYQGSNKTIVTNSLIIVEVLSNSTKDYDRGGKFLAYRSIPEFQEYILIDQYSYHIEQFAKNSNGKWVLTEYDSEESVLTLESVEFQMPIREIYARINFDIKDEEVNESISDIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY03</accession>
    <name>A0A2G4EY03_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54358">
        <property type="protein sequence ID" value="PHX54358"/>
        <property type="gene ID" value="CP500_016520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013787604" evidence="1">
        <location>
            <begin position="30"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="157" mass="16994" checksum="9CE15DB95D623BE3" modified="2018-01-31" version="1">MNLKSIAKTNLLLSSLIISLGLQALPAAAASVTDAQVSALVEALRQAAPPQTANDGMYSQWQLLPSNISRWAKFCTKQDLTPQQFEADATKAKSIVTCIARDLLRDEYKASGNNETAAIRRAACWWMTGESAACKSGATATYADKVVSVYQQQRPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY06</accession>
    <name>A0A2G4EY06_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016345</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54412">
        <property type="protein sequence ID" value="PHX54412"/>
        <property type="gene ID" value="CP500_016345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="8"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="49"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="226"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="386" mass="43095" checksum="A148CE5C619C7630" modified="2018-01-31" version="1">MTKPYSILSCDGGGVRGLISAIILERLEQKLRQKAPDKKLRDYFDLIAGTSAGSLTACSVARGIDATRIKKLYLERGIEIFPPFNNVFKSFINRLAVGFSTQPIYDGLGLKQVLQVVFGQGEINFDKLPKPLKIENLPAKSLLFQDLPKPVLITSYDIYNRQPVIFKNTKVAHEKIPVWEICRSSAAVPVAFPAHIMTNPDFLKNWQEEGNQIPVAGNIRGIPLIDGGFVASNPALCAIAERLRWNHNPPANPKWLQNPASPWRDVVDIKDIVVTSLGTGQSVKRIGISESQTWGAGEWINPLDGIPILDVFSDGSSDGIIYIINQLMNSEQYVRFQPILSKNYPAFNANQQILLEIQQEIEKSFLTNQKEDEKLNKLADVLLSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYA2</accession>
    <name>A0A2G4EYA2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54147">
        <property type="protein sequence ID" value="PHX54147"/>
        <property type="gene ID" value="CP500_017630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="143" mass="16172" checksum="314722EB981DEC1B" modified="2018-01-31" version="1">MSENQDESCSQGLRVCVESLGLAHIERHIFICADQTVPKCCDRAASLEAWNYLKKRLQELGLDRPSVSPPTCVFRTKANCLRVCTQGPIMVVYPDGVWYRDVTPPVIERIIQEHLLNSKVVQEYAFLTHPLPVTTLTEPNFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ19</accession>
    <name>A0A2G4EZ19_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CP500_016125</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000101">
        <property type="protein sequence ID" value="PHX54437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54437">
        <property type="protein sequence ID" value="PHX54437"/>
        <property type="gene ID" value="CP500_016125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="16">
        <location>
            <begin position="371"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="14">
        <location>
            <begin position="463"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="15">
        <location>
            <begin position="764"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="408"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="11">
        <location>
            <position position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX54437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="970" mass="109494" checksum="2C2971B7B9ADBA71" modified="2018-01-31" version="1">MSSPTRKPFLSKLIGNVPLRAILIVPFVVQIVAAVGTVGYLSFRSGQKAVNDMAIQIQEEVSDRTKQQVLSYLERPTLTLETIAAAIKTEQLDLNDQIKQQWFFWHLVDRKTVMAVQLITPEGNSVLVERVPNQIETRVRNSTTTPDREVYRLDNRGDRLELIERQKNFDSRTRPWYKNAIAAQKPVWTSLYINVNTSVVAITATYPVYDRAEQLLVVLSSRFDIPRIYDFLKTLEIGKTGQFFIINRDGEMIASSKIEQPYIIKGKDLETIKAFEIENPTIQATAKQLIAKFGNFTAITDTQQINFDINGERYFVQVTPMQDEWGIDWLGVVVLPESDFMAQINANTQTTIFLCIGTLLIATILGWYTSRWVTQPLQRLSQASEAIAAGNLEQNIELSGKNELGRLAQSFNRMAQQLREAFNHLQNTNVELEQRVEARTVELQQAKDMADSANLAKSNFLANMSHELRTPLNGVLGYTQILQRTESLSPKARKGIDIIYQCGSHLLMLINDILDLSKIEADKVELHPTSFHFPSFLQGVAEICNIRAEQKHIAFNFAIDPQLPVGVKADEKRLRQVLINLLGNAIKFTDKGSVTFKVEVIECQSSHPECSINQSIFNQSSMENRSESSIENHQSIFNQCSMENRSESSIENRKSKIENKQNRSVRFQIEDTGVGITPEQLEKIFMPFEQVGNTKKQAEGTGLGLSISQKIVALMNTTIQVQSQAGVGSIFSFEVELPDALDWADTSWVTQQGAIAGYEGKKRKILVVDDRWENRSVLIHLLEPIGFELIEAENGQEGMDRALSEQPDLIVTDLAMPVMDGFEFLQKLRSYPELKEMPVLVSSASVFEIHRHKSLAAGGSDFLPKPIQADILLELIQKYLQLDWIYNENQDSKVNSKGKIAPDQILPPAIEVLQQIRELAKLGDLDGVVEIAQQIQTTNSEHFAFAQELISLAESFQTKPLRAFIQQYID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZA2</accession>
    <name>A0A2G4EZA2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polyketide biosynthesis operon protein CyrO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54839">
        <property type="protein sequence ID" value="PHX54839"/>
        <property type="gene ID" value="CP500_014010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="34"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="516" mass="57647" checksum="5C8D536809FDAE60" modified="2018-01-31" version="1">MPRWFNTAGPCREDIHYLLPATRRLPNLERLIAQQNYFVIHAPRQVGKTTAMLALAKQLTDSGKYTAVMVSAEVGAPFSQDIGGAEDAILGAWRDNIAFRLPPELQPPDWTSIQSGQKIRAALQAWAESSPRPLVIFIDEIDALQDLALISILRQLRDAYPNRPKAFPQSVGLIGLRDVRDYKVAAGGSDRLNTSSPFNIKVRSLTLRNFNAEEVAELYAQHTEDTGQVFTPEATALAFELTQGQPWLVNALAKEIVEELVTDESIAITTEHILESKEIIIKRQDTHLDSLAERLRENRVKAIIEPMLAGLELGNVPNDDIQFLIDLGLCKMDSQGGLAIANPIYREVLPRVLTVTPMASLPQIAPSWLTAQGKLDTQALLKTFMAFWLQHGEPLLKSASYPEIAPHLVLMAFLHRVINGGGTLEREYAIGRDRMDLCLRYGEVTLGIELKVWRTKKADPLSKGLEQLDGYLARLGQYSGWLVIFDRRENALELEERLKTEIHNTPMGRSVTVIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZC7</accession>
    <name>A0A2G4EZC7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54870">
        <property type="protein sequence ID" value="PHX54870"/>
        <property type="gene ID" value="CP500_013615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8197" checksum="3592BF87B3264410" modified="2018-01-31" version="1">MKQPWGEGGFIEIVCASQILSVKPAPTAPERNINPHFPKKKFERADARKRVKRKEGKEQKGKRAEKSPRGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZG7</accession>
    <name>A0A2G4EZG7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54904">
        <property type="protein sequence ID" value="PHX54904"/>
        <property type="gene ID" value="CP500_013530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="10929" checksum="093705BF17A8ACB7" modified="2018-01-31" version="1">MTIFLPLLQFNNLTAIGLFATLCHSPNPIESMLIVGAVTAMVGGLVVLVPASAVTMVFLATTIVQMIMTGATLESIAAAIAAQLGTVAMSLGLVSQLVEKIKGIIGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZN9</accession>
    <name>A0A2G4EZN9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54958">
        <property type="protein sequence ID" value="PHX54958"/>
        <property type="gene ID" value="CP500_013110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="23"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="29228" checksum="666497D0F30CE4A5" modified="2018-01-31" version="1">MLLFDREMRLPTSAELPSSDDTPVDNENQNFLPNLLLFLLKFHWRQRNDWFFAVDMGVYHTTGVSHLVPIVPDGFLSLGVERFKGETLRLSYVLWEENNIPPIFALEIVSQTYGGEYDKKIDIYAKLGVLYYVIYNPYYWRRDQHQPFEVYRLVNGEYEQQIGEPFWMPEVGLGIGRGRYSDGERQLEVLYWFDERGSRYLTAEDTADRAQQRAEESAQRAEESEQRAEEIQQQLARYRDRFGELPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZU2</accession>
    <name>A0A2G4EZU2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage tail protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55036">
        <property type="protein sequence ID" value="PHX55036"/>
        <property type="gene ID" value="CP500_012775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="225" mass="26372" checksum="49115AF547FEE96D" modified="2018-01-31" version="1">MISFGLITEGLTDQIVIENILAGFFNSPNIEVTPLQPKRNKDNQNKSQYGGWTLVFDYCHSKKFQESFRFLDYIIIQIDTDVSEDYNIAHQDENGEFTPQQLIAKVIEKFRSAIGEDFYNTNQQKILFAISVHSLECWLLPLYYTDKKKQAKVKNCLDTLNLPLAKKHKFTIDPNAKNPEYYREISKQYSKQKVLMKHYAENPSLKIFIEEIQSRDIKIGDEEDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZV5</accession>
    <name>A0A2G4EZV5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Branched-chain-amino-acid aminotransferase</fullName>
            <shortName evidence="17">BCAT</shortName>
            <ecNumber evidence="17">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ilvE</name>
        <name evidence="18" type="ORF">CP500_012790</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 17">Acts on leucine, isoleucine and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 17">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 17">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 16">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6 17">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 17">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 17">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 15">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="17"/>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55039">
        <property type="protein sequence ID" value="PHX55039"/>
        <property type="gene ID" value="CP500_012790"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005785">
        <property type="entry name" value="B_amino_transI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01122">
        <property type="entry name" value="ilvE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 17" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="14 17" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 17" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00003109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU364094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PHX55039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="304" mass="34256" checksum="E92CD14D29BB73ED" modified="2018-01-31" version="1">MDSFLPIAYFQNQFLPFTDAKISIATHALHYGTGVLGGLRGIPDPENRDRILLFRLDRHCQRLSQSASFLQCDLAADKIQSVIVDFVKKNQPTQSFYIRPFIYTSSLGIAPRLHNVETDFFVYGLELSDYLPKEGVNCRISSWYRQEDRSLPLRGKISGAYITSALAKTEAVQSGFDEAIMMNSQGKVSEASGMNIFVARNGKLVTPGFEQDILEGITRDSVMTIAKDLGIEIIERPVDKSELLIADEIFLCGTAAKITPINRIENYHLPKERPITEKLLEKLTGIIENRDSKYKDWVFPISLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZV8</accession>
    <name>A0A2G4EZV8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55035">
        <property type="protein sequence ID" value="PHX55035"/>
        <property type="gene ID" value="CP500_012770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="100" mass="11200" checksum="A412BD953313B3BA" modified="2018-01-31" version="1">MQAYKLRGKIDATGKLVVGEPVNMPPGDVEIIVLQLADTVVKQASSSESAIEPETPKKKFNTTVKAFQGLFERDTVPEPLDFDDPDKQAKWEYLKEKHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZX4</accession>
    <name>A0A2G4EZX4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carbonic anhydrase</fullName>
            <ecNumber evidence="3">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_012825</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55045">
        <property type="protein sequence ID" value="PHX55045"/>
        <property type="gene ID" value="CP500_012825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013814559" description="Carbonic anhydrase" evidence="6">
        <location>
            <begin position="32"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="24855" checksum="07E1BC4CFE1BEFB0" modified="2018-01-31" version="1">MTDPKKTGKMSRRSALLMAGAGTLVATIAPALLKVEAANANTQTTSNITPDAALKKLMDGNRRYIDQKRTFPDQGPSRVLEVAKGQHPFATILGCSDSRVPPEILFDQGLGDLFNIRVAGNILNDAVVGSMEYATAELGVPLVVVLGHERCGAVKAALEGKPLPGKIGSLAAAIKPAVDATKGQPGDALDNAVRAHVKMSVNQLKKSSPIIAEAVKAGKLKIVGGRYDLDTATVEIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F034</accession>
    <name>A0A2G4F034_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heme NO-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55113">
        <property type="protein sequence ID" value="PHX55113"/>
        <property type="gene ID" value="CP500_012625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038158">
        <property type="entry name" value="H-NOX_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011644">
        <property type="entry name" value="Heme_NO-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07700">
        <property type="entry name" value="HNOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="SSF111126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNOB" evidence="1">
        <location>
            <begin position="2"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="20800" checksum="A22A04371FAAC4B0" modified="2018-01-31" version="1">MYGLINRAIQDMVCEHFDEATWGKIKQNAQVLDEQFLILESYPDDLTHRLVKSASQVLGLSGAEIMQAFGEYWVKFTATAGYQEILDMAGDTLPEFLENLDDLHTRIGVQFPKLRPPSFESTEVAENVIELHYSSTREGLAPMVIGLVKGLGDRFETEVDITQTQSREAGFDRDTFRIEYRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F035</accession>
    <name>A0A2G4F035_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_012475</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000064">
        <property type="protein sequence ID" value="PHX55119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245903">
        <property type="entry name" value="M.Tbo703ORF12475P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55119">
        <property type="protein sequence ID" value="PHX55119"/>
        <property type="gene ID" value="CP500_012475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="350" mass="40167" checksum="438FF2ACC22A018E" modified="2018-01-31" version="1">MRFIDLFSGIGGFRQGFEKVGFKCVFSCEINSKCREVYTDNFGEVPFADVSNINPTDLADFDVLVAGFPCQPFSICGKKLGFEDTRGTLFFEICKIIKVKQPQVVVLENVKHLIHHDKGNTLKVIIASLKDLGYSVNYQILNAKDFGIAQHRERIFIIATKGKEFNFSRLKTKFPPKLREFLDETGDFEILDKSEYTLIEYPRKQDSGLLFVGYRNKGTWKTGVRPNTEHLSRVHRQPNRIYSVDGVHPTIPSQETSGRFFIYFRDRDLVRKLTLKECYRLMGFPEDFKSYPSAGESYKQIGNSVCVPVVEAIAKEILSQSLLYDEIKETQRHQESRLLEEVGILVKTIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F051</accession>
    <name>A0A2G4F051_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55139">
        <property type="protein sequence ID" value="PHX55139"/>
        <property type="gene ID" value="CP500_012200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="12483" checksum="1B5557E9ACE83C46" modified="2018-01-31" version="1">MQLTTPEPDKQLPISIPHDQIAEFCQKNAIAKLSLFGSILRSDFRPDSDIDLLVEFIPGNKIGWRIVTMEIELTEMLGRQVDLRTPEELSQYFRKKVLDSAQVLYVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F088</accession>
    <name>A0A2G4F088_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Bacitracin ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_012365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55170">
        <property type="protein sequence ID" value="PHX55170"/>
        <property type="gene ID" value="CP500_012365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13553">
        <property type="entry name" value="PBP2_NrtA_CpmA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005890">
        <property type="entry name" value="NO3_transporter_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044527">
        <property type="entry name" value="NrtA/CpmA_ABC-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01184">
        <property type="entry name" value="ntrCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="5"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="666" mass="73440" checksum="A92C912E15390211" modified="2018-01-31" version="1">MSVLIAVEQVGKTFNLSDGGTYVALKGIDLEIKKGEFISLVGHSGCGKSTLLNMVAGLDLPTEGLVTIDGQRITKPGPDRMVVFQNYSLLPWRTVRENITLAVDSVMNGLPQAERLDIIQKHIDMVGLGPHSEKQPALLSGGQKQRVAIARALALRPKLLLLDEPFGALDALTRGNLQEKLMEICQEYEISALMVTHDVDEAVLLSDRIVMLTNGPESKIGGILEVDIPRPRKRMEVVTHPSYYALRSEMIYFLNQQKRVKKLRARKVPAIARHGLEKVNLEIAFIPLAACAPLAVAKEKGLFAKHGLDEVHLVRETSWRGIVDGIAAGYLDAAQMPSGMAMWLSLGGHQEKPIPTVTALTMSRNGNGITLAKRFYDEGIYTLADFKKMLQRTPAQTHRMAIVHPSSMHNLLLRYWLAAGGIDPDRDVLLKNIPPAQMIVDLQGGTIDGFCVGEPWNLRASMEGVGFTVATDLELWPGHPAKILGVREEWANAYPNTHIALVKALLEASHYCADPAHAAEVSEIVAGREYVATDKSYIQLGDPSSVACNLDSPMREYAHHLFCGDGVNRPSRTEQLWHMVQMARWGDTVFPRNWVEILERVVRVGAFSTAARELGMSDITYNRGSLPLFDGSVFNADDPIGYLNNLEIKRDFTMAEVILDSGRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0N2</accession>
    <name>A0A2G4F0N2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Holliday junction ATP-dependent DNA helicase RuvB</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ruvB</name>
        <name evidence="9" type="ORF">CP500_011685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a complex with RuvA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55298">
        <property type="protein sequence ID" value="PHX55298"/>
        <property type="gene ID" value="CP500_011685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00016">
        <property type="entry name" value="DNA_helic_RuvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041445">
        <property type="entry name" value="AAA_lid_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004605">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008824">
        <property type="entry name" value="RuvB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008823">
        <property type="entry name" value="RuvB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42848">
        <property type="entry name" value="PTHR42848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17864">
        <property type="entry name" value="AAA_lid_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05491">
        <property type="entry name" value="RuvB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05496">
        <property type="entry name" value="RuvB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00635">
        <property type="entry name" value="ruvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="88"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="96"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="366" mass="40426" checksum="D8086546C9EA17A9" modified="2018-01-31" version="1">MAIISSKQQPPDPNLPEDIAPATPKKIKNKAVKPQSESLVEPEELADETNSKQDDKIRPQRLAEYIGQKDLREVLAIAIAAAKSRGEPMDHLLLYGPPGLGKTTMSLILAAEMEVDCKITTAPALEKPRDIVGLLINLKAGDVLFIDEIHRLSKVTEEILYPAMEDCRLDITIGQGKSAKIRSIPLKPFTLVGATTKVGSLTAPLRDRFGLIQRLRYYEIDELSLIVQRTAQVLDTKITPEGATEVARRARGTPRIANRLLRRVRDYSEVKNLKPITAEVASIALELFNVDPLGLDWTDRCLLTAMIENFNGGPVGLETLAASTGEDTQTIEDVYEPYLMQIGFLQRTSRGRIATLAAYKHLGLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Q0</accession>
    <name>A0A2G4F0Q0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55331">
        <property type="protein sequence ID" value="PHX55331"/>
        <property type="gene ID" value="CP500_011340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="25384" checksum="BA16A114BE314CA6" modified="2018-01-31" version="1">MYKPPFSQAQLDRTVLSKAYAIAQKAWHHNLAKLMTCVVILLPANLAFSAPTYLGSEPNTETDSAKFTQKVNIILAQESTQLPLSIRYGGTEAIRGFVLLELIVPNRDTTQPAYGGKLRLYDVHLAKMFETSHFLCQQFRGVSGYEWVYSAGNGSIRMGKFKISCSLASEMASTYGLGKLERTSIARDTEGGTPESDVYSIPILDITGSKVQRWMNFAQNFKPTIRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Z5</accession>
    <name>A0A2G4F0Z5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_010835</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55429">
        <property type="protein sequence ID" value="PHX55429"/>
        <property type="gene ID" value="CP500_010835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="7"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="257" mass="28459" checksum="AF07645D15B6F30B" modified="2018-01-31" version="1">MKYWYETLAVAQRILIELFRRKRSLILWSIFPVSILLINGAILQERANLTTAKAFESAAPASLVGAALFFSCLGGSVATVVAEREQHTLKRLFISPLSGSSYFLGIFLAHSAIGIGQVILVYAIASFLGAQFQGSVFLGSVIILLSIISYVGVGFILGTQFARRTEDVNSLVAAFGVPLLILGGAFLPTALFPKNLLELAKYNPIYHMNEALIQVWANGKNFDDISEHFWFLFIFSIAMIAGGWLSYRRMLRVERRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Z6</accession>
    <name>A0A2G4F0Z6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55430">
        <property type="protein sequence ID" value="PHX55430"/>
        <property type="gene ID" value="CP500_010840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="358" mass="39767" checksum="741C59F4AA9D5C1C" modified="2018-01-31" version="1">MSNLVQRLEITAHPQLEKSLGYRGDNRWIAWRWEPEIDQLICSDGKIVSTGNNLAWLVFLQHDLVQPVLEDYHLAKADRHSLLLDRHSRNLYIGEGTEIQNLLEQPESLVLLTCLDRNTKGDSLRDSFASRKFGETWQQKLAKTTKSDHFRHFINLIPVSIVATLIGALAVGTGMWVVPAAQQKLTQKTAPTSPMSFEANCYLGNSYKFSSHVGSLTGNKELHLIAAYEATSPQDNGNSSKNAIAVKVQRQNKPIILALSAYAPINWNVTIEPGAVIEKIIISGYEKQTISGVGGIPIEEYSYKGTGNSLSEGNFMYQWESTTDSSNSSSIVTKLEQISQTNLTSFQGCYRGTSFVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F107</accession>
    <name>A0A2G4F107_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55441">
        <property type="protein sequence ID" value="PHX55441"/>
        <property type="gene ID" value="CP500_010895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="283"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="400" mass="42690" checksum="7B99F23220AEC3C2" modified="2018-01-31" version="1">MEIFKFFRPAPQMVASLLSIFLAITIALNAWTISPASASATVQNPQKLELQDSELPATASNNSFVTAAVDRVGPAVVRIDTERTVSRNLDPVMEDPLFRRFFGDEFRTQVPRQERLRGQGSGFVIDKSGTVLTNAHVVDQADRVTVTLNDGSVFPGEVLGTDEVTDLAVVKINTKGVNLPVAVLGDSDAVKVGDWAIAVGNPLGYNNTVTLGIISTLKRSSAAVGIPDKRLDFIQTDAAINPGNSGGPLLNGSGEVIGINTAIRADAMGIGFAIPINKAKAIYTQLAKGEQVSHPFLGIQMIDLTPEIARENNADPNAPLMIPEVRGVLVMRVVPNTPAEKAGIRKGDVIVQIDGKTVTAAEKLQNLVENSQIGQSLKLKVRRGSLTKDVAVQTAQLRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F144</accession>
    <name>A0A2G4F144_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_010790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55458">
        <property type="protein sequence ID" value="PHX55458"/>
        <property type="gene ID" value="CP500_010790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030660">
        <property type="entry name" value="ABC_branched_ATPase_LivF/BraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039137">
        <property type="entry name" value="ABC_branched_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="14"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="245" mass="26697" checksum="A2BCA5F319A653D2" modified="2018-01-31" version="1">MHDSSPKTTKNILLELKNLSVNYGGIQALQNINLTINAGEVVSLIGANGAGKSTTLRAISKIVNLHQGQIIYNGRDITRRQAHEVVKLGIAHSPEGRRVLAQQTVLTNLELGAYVRSQIAEIKADLDYQFKLFPRLAERRHQLSGTLSGGEQQMLAIARALMSRPKLLLLDEPSLGLAPAIVKEIFAIIQHLRSTGVTILLVEQNASLALQIADRGYVLEAGNITLTGLASDLLNDDRVRRAYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1D1</accession>
    <name>A0A2G4F1D1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55562">
        <property type="protein sequence ID" value="PHX55562"/>
        <property type="gene ID" value="CP500_010265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="51" mass="5452" checksum="AFA28BD9D134D0B2" modified="2018-01-31" version="1">MGEVSDYDNARQLAAYAGLTPSERTSGTSVKGKTRLSCTGNVRLRKVGYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1L8</accession>
    <name>A0A2G4F1L8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="5">ATase</shortName>
            <ecNumber evidence="5">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
            <shortName evidence="5">GPATase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purF</name>
        <name evidence="11" type="ORF">CP500_009510</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5 9">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55639">
        <property type="protein sequence ID" value="PHX55639"/>
        <property type="gene ID" value="CP500_009510"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="10">
        <location>
            <begin position="23"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5 7">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="488" mass="53081" checksum="ADA6FBC4BC49774F" modified="2018-01-31" version="1">MIPNHSFAADEHSSKPDKPEEACGVFGIYAPGEDVAKLTYFGLYALQHRGQESAGIATFDGDKVHLHKEMGLVSQVFNESSLGHLPGNLAVGHTRYSTTGSSRVINAQPVVVETRLGSLALAHNGNLVNTKELREKLLARKCEFVSTTDSEAIAVAIGYEVGKGKDWLEAAISAFAMCQGAFSLTIATPTGVMGVRDPHGVRPLVIGTLPTNPVRYVLASETCALDIIGAEFLRDVEPGELVWITEEGMASFHWSQKQKRKLCIFEMIYFARPDSIMEGENLYSYRLRIGRYLAAESPIDADIVIGVPDSGIPAAIGFSQASGIPYAEGLIKNRYVGRTFIQPTQAMRESGIRMKLNPLRDVLEGKRVIIIDDSIVRGTTSRKIVKALRDAGATAVHMRISSPPVTHPCFYGIDTDNQDQLIAATKSVAEIAAQIEVDSLAFLSWKGMLKATHEDPNSFCSACFTGDYPIEVPELVKRAKLILEKAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1M1</accession>
    <name>A0A2G4F1M1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_009900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6 7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55638">
        <property type="protein sequence ID" value="PHX55638"/>
        <property type="gene ID" value="CP500_009900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="65"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="290" mass="32154" checksum="865BD29D6CF9B07F" modified="2018-01-31" version="1">MSNIPLIGLKADQFRHPLDLEATNALKQLPGLDLMVRQLLGQLGEQFFRLENLASSVQVGENQLPHLHQLLLDACKTLDLEVPQLYVRQHPMPNAYTFAMRGKQPFVVMHTSLIDLLTDEEVKAVIAHELGHLKCEHGVYLTLANLIVLAAGQISPVGTVLVQGLQTQMLEWLRCAEFTCDRAALLATQDPRVVASVLMKLAGGSPTLAPKLNVDAFLAQARAYDDLSSTELGEMLKQAQTAQLSHPVPVLRAREIDRWASSKNYESLLAQSRSVCYDSQSKTKGGWRNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1N7</accession>
    <name>A0A2G4F1N7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Divergent PAP2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55655">
        <property type="protein sequence ID" value="PHX55655"/>
        <property type="gene ID" value="CP500_009595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003832">
        <property type="entry name" value="DUF212"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31446">
        <property type="entry name" value="PTHR31446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02681">
        <property type="entry name" value="DUF212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="152" mass="16375" checksum="D63B65FB96EE238C" modified="2018-01-31" version="1">MQEICSGILNNHVLVISLIACLAAQVLKLPIELIKNRKFNLQYLVTTGGMPSSHSSFVGALAAGVGQTLGWESPEFAIATIFAIIVMYDAAGVRQAAGKQARILNQIVDEFFEEDHNLNEARLKELLGHTPFQVLVGLGLGVTISWLAGPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1X4</accession>
    <name>A0A2G4F1X4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dTDP-4-dehydrorhamnose 3,5-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Thymidine diphospho-4-keto-rhamnose 3,5-epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rfbC</name>
        <name evidence="4" type="ORF">CP500_010670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose</text>
            <dbReference type="Rhea" id="RHEA:16969"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="5.1.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.13" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55477">
        <property type="protein sequence ID" value="PHX55477"/>
        <property type="gene ID" value="CP500_010670"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21047">
        <property type="entry name" value="PTHR21047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01221">
        <property type="entry name" value="rmlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="2">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="181" mass="20309" checksum="AD35C2BEE33F2149" modified="2018-01-31" version="1">MNVISTEIPEVLIIEPKIFGDDRGFFFESFNYKAFAEKTGVTGEFVQDNHSKSSKNVLRGLHYQLQQPQGKLLRVVSGEIFDVAVDIRKGSPTFGKWVGCMLSATNKQQLWVPAGFAHGFLVVSETAEVLYKTTEYYAPSHERCILWNDHDLAIDWPLDGAKPILSAKDNAGQTLKRAQVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1X5</accession>
    <name>A0A2G4F1X5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_009165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55761">
        <property type="protein sequence ID" value="PHX55761"/>
        <property type="gene ID" value="CP500_009165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="543"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="63"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="372"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="578" mass="63441" checksum="61E130CFB320B537" modified="2018-01-31" version="1">MTRPLTPANRTLERSTWTWQDGLLILAIFSLILVIVQTASQFTGDYNPTFKIETTLSVLPIYTAQTLLRMTVAYFLSLLFTLVYAYSAYRSPLAAKILIPLLDILQSIPVLSFLPGVVLALVTLFPGQRIGVEIASIILIFTGMTWNLTFSFYQSLSGIPQELKEAAKVYRLNAWQQFWTLELPAGAIGLVWNSVMSVAGGWFFLIAIESFTLGDKNFQLPGLGSYLGKAANEGNFGAIGWGLAVLIGVIIAIDFFVWQPLIAWAEKFKYQAVESANVPQSNVLDFFRRSATLRMLKSRISPIGDSFDRGLARAFAPASLPKNPQQTNPLGNWINWIFVSGFAVIVLWGTWEAVLLLRVLSLSDWQKVIGGAIFTALRVVCALFLSLLWTVPVGVAIGRNPRLAQILQPLVQIAASVPATALFPVLLLALIQTGGGLQIGSVALMMLGTMWYLLFNVIAGAQAIPSELFEAARVYKLSLVQRWKNLILPGIFPYLITGIITAVGGAWNASIVSEYVQFKGQIIATDGLGETISQATASGNFPLLLAATSVMSLLVVLTNRLVWRPLYRLAQEKYQLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F251</accession>
    <name>A0A2G4F251_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Coproporphyrin ferrochelatase</fullName>
            <ecNumber evidence="2">4.99.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_008800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:49572"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:68438"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="4.99.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:49574"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ferrochelatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.9" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55840">
        <property type="protein sequence ID" value="PHX55840"/>
        <property type="gene ID" value="CP500_008800"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="PTHR11108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="368"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="368"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="400" mass="44780" checksum="EB076D283285E708" modified="2018-01-31" version="1">MVASPEKIEFKTSPAPASNDRVAVLLMGYGEVESYDDFANYNEQALNLLTAKFAPVPTWIYPPLAKILAIFDLHEWSHQHGQFVSPHNAIFEQQRAGIEHNLQEKWGDKVKVFKAFNFCAPFLPEQVIPQIKAEGFDKILIYPLLVVDSVFTSGIAVEQVNKALAQTFDGKEHWVTGQRYIPSFYDEPAYIQLMADLVEEEIKNDLAVAHLPSQIGIVLMNHGCPHKAKGFTSGIVESQALYDRVRERLMYRYPLISVGWLNHDTPLIEWTQPDATLAAKNLIDLGATAIVFMPIGFATENHETLLDVDHVIESLQKQRQGVTYRKLPCVNDHPEFLKMAAEWANPQIEALLSESAVAVNPNLVVRDHVHSHGDHGHSHGDHGHSHGDHGHSHGGHGHNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F255</accession>
    <name>A0A2G4F255_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55829">
        <property type="protein sequence ID" value="PHX55829"/>
        <property type="gene ID" value="CP500_008735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031975">
        <property type="entry name" value="Pilin_GH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16734">
        <property type="entry name" value="Pilin_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="283" mass="31897" checksum="45812C23D53D696F" modified="2018-01-31" version="1">MSQLIIANVAAPFVLSQTGSILLFVSIIPIEMFVLFLCLKSSGIAITFPRLFIAVLVTNIATSILGIPLVFAQPISSLLMEILSISFLLSFSIESIIYGIILKAKNIPRCKIVQFSSLSNLASYIIFYLALISTFGYNNYESLFLTPNPRMISSEVRRDIRSYISLQKSFYRDKNRLANNGQELANNYWQELKFGKQKQNRYGFYRYDSQGDATKASFTATSKRKDFTSYRATIFIVKDKDNYQFIQGICETDKPSMTAPEIPQLVNGKFQCPPGSSDKSDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F278</accession>
    <name>A0A2G4F278_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55577">
        <property type="protein sequence ID" value="PHX55577"/>
        <property type="gene ID" value="CP500_010125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="187" mass="20864" checksum="ADEE6CCB23F9C879" modified="2018-01-31" version="1">MNDQTEKQKLWKVYGILIGVMLGGAVFVLGGQAAWNAIQENLAKSNTPSNSTPQSLPQSLPPSPSSTVSPSDIPLRTTPEQTLNNFYALTTTDNKAAGQVFTTDDFKKKYPSSDNNKKWVSLYNFIKVTQIKPIEQSPTRAKMTVWLLYSFKDGREQACEYRDFTLILNNNNYLIDDIGEATQTSCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F284</accession>
    <name>A0A2G4F284_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin--[biotin carboxyl-carrier protein] ligase</fullName>
            <ecNumber evidence="2">6.3.4.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_008600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.15" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55871">
        <property type="protein sequence ID" value="PHX55871"/>
        <property type="gene ID" value="CP500_008600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003142">
        <property type="entry name" value="BPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02237">
        <property type="entry name" value="BPL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="6"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="29128" checksum="C7559FE0D07EC2B7" modified="2018-01-31" version="1">MPQSLESDRPNLPQWLHWLDTCPSTNTIAIARAAQLNHGDVVFTKRQTSGRGQHGRTWHAPTGVLTASFVLDNLNPNLLPGLSLAVGLAVIYAIEDLVPDCRTLLRLKWPNDIWIDRRKLAGILCEATSSHVSGKTRAVVGIGINLCVDFDRSGLDASAIGNAVSLHSIARQVPDELCLLDRLRHYLLQLAHMFSQTEKPAEKSGLARLLPELQHRDALFGCNVAIELSDKTICGQAAGIDESGRLLLRLLGDRIQAFSSGRVRVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2C0</accession>
    <name>A0A2G4F2C0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55923">
        <property type="protein sequence ID" value="PHX55923"/>
        <property type="gene ID" value="CP500_008080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013653287" evidence="1">
        <location>
            <begin position="21"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="15365" checksum="C6D41831D57139D0" modified="2018-01-31" version="1">MKKLLTTTIIFLSTAIPCLAMTPSELAIFATNYKYNEKAPVAYSYYNKACLTNVSVSLVKIMDLGNGRIGGITNQFVCWGATYTYFEMARGNLQSIRAFAAIRAGRTTQYTNWGPVANPEDDLTPAQLISVAKTMTANTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2H1</accession>
    <name>A0A2G4F2H1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55667">
        <property type="protein sequence ID" value="PHX55667"/>
        <property type="gene ID" value="CP500_009665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="80" mass="8968" checksum="7E4F7ABF2DABC3B1" modified="2018-01-31" version="1">MKDKFIDWLNIFLVADVFFVFASFAWFAIAVLGRSTGVNLGFDLWYSLWQPVFNPALGILMGGAILSGIINQVSKRLNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2M2</accession>
    <name>A0A2G4F2M2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55707">
        <property type="protein sequence ID" value="PHX55707"/>
        <property type="gene ID" value="CP500_009435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="350" mass="39555" checksum="A857F4F7E453EACF" modified="2018-01-31" version="1">MIFINPKTDYAFKKIFGSSESKDILISFLNALIYEGSSTIKDLEIINPNLPPKIEGLKDSYLDVKAQLKDGTLVIIEMQVINVQSFGKRVFYNAAKTYAFQLQAAQGYRLLKPVIALTITDFEMFPESEDFSSRFVFKEVNKNFTYPENDLDLVFVELPKFTKELEELETLADKWIYFMKNARSLTSVPETMDSVPEIHQAFDIANQVKLTREEVEDLDRIEQFIHDQQGAIIKAVQEGIEQGIERGIERGIEQGIERGIEQGIEQGIEQGIERGIEQGIERGIEQGIEQGIEQGIEQGIEQGIEQGIERGKREEKLAIARQLLSQLDNATIAQVTGLSVEDVQSLRGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Z9</accession>
    <name>A0A2G4F2Z9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56126">
        <property type="protein sequence ID" value="PHX56126"/>
        <property type="gene ID" value="CP500_006980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013727330" evidence="2">
        <location>
            <begin position="32"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="18617" checksum="B2EEB2A7C5A4063B" modified="2018-01-31" version="1">MFHHNLKFKKISLLTTASIGLLVSLATISLAGGPPPQGKPVSRPATTPPANGKPVSAPTPAMPQDAPPRFPFPGARVTPVDGMVTIKLVNTTNAVINYQVVGMSQSRTLGEQSEISLKNLKTPITLTYQRPDGGLLLVRTQATATAGMLQISFGATTDLGADTKSLEVQEDGKVFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F346</accession>
    <name>A0A2G4F346_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55887">
        <property type="protein sequence ID" value="PHX55887"/>
        <property type="gene ID" value="CP500_008300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="269" mass="29980" checksum="E36D7498A2DCDFD5" modified="2018-01-31" version="1">MLTAVTPDSEHHLFKLPSQADTSPRMTIFCDLDGPIVDVSDRYYATYQHGLADTQAVYLDRGINLNLQILSKQQFWQMKQNRVPDTEIATSSGLSGPEIHVFLGCVSRIVNQPDLLHLDRIQPGVQWAIALLHSRGVRLVLVTLRPKDQAVQILQNYGLARLFTCICGTQMPDAAYHNYAALKTELLAEVAEEFESSLGSAWMIGDTEADILAGQALGIPTIAVTCGIRSSQQLQQYQPNFILNDLMIAVHHLLGSRPQVRSYNEQQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F372</accession>
    <name>A0A2G4F372_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YdcF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55917">
        <property type="protein sequence ID" value="PHX55917"/>
        <property type="gene ID" value="CP500_008045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="140"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="330" mass="36084" checksum="CA18B7393D60B1E5" modified="2018-01-31" version="1">MFVLLARILFLFLLFSLVKSWWDQSGGKDNPLLDRLRVLLLISLLLLAFFAPDTPVGAAIFGLVAFFFKPLGFSITLLVIASALITNGGIRNPAPKLILAALLVLILSSMPVVALWFADQAEREAAAAVQTTCCDETAAAIVLLGKGTTQPHIPNRVAIQLTDTGNRLPYAAVLYRKQLAPLVIVTAGPRPELENYTGEAKDIQTLLASNMGVPRSSIILDENGRNIRTSAQEVRKILDSRGLERKVLLVTSAIQMRRASLAFADLGIKVVPRATDFYTFQPTAGGRSRLRIDATDFLPSAEALVTTTRVFDEYLGSFYYFFRGWLAPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3V9</accession>
    <name>A0A2G4F3V9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance/extradiol dioxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56411">
        <property type="protein sequence ID" value="PHX56411"/>
        <property type="gene ID" value="CP500_005730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="16431" checksum="41006035E906D585" modified="2018-01-31" version="1">MHHASIRTANIHKAIAFYEQLGFTVSDRFTTGYTLACWMEGLNGRIELIQIPEPKPAPDAFGDEHYVGYYHLSFDLTEATTDLPTWLQSLKQRFEEAAKEEPSQFQPLKVLLEPTQQAIGQNVYEVAFIADTDGLPLEFIRRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3X4</accession>
    <name>A0A2G4F3X4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56446">
        <property type="protein sequence ID" value="PHX56446"/>
        <property type="gene ID" value="CP500_005440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="41" mass="4730" checksum="915669E8D331B8B5" modified="2018-01-31" version="1">MPARDIYHQVVKQGLIKAGWTITHDPYPLAWAKRNLSIIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F404</accession>
    <name>A0A2G4F404_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD(P)-dependent alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_005000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56514">
        <property type="protein sequence ID" value="PHX56514"/>
        <property type="gene ID" value="CP500_005000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="4">
        <location>
            <begin position="10"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="349" mass="38143" checksum="8E22A2B6B4739D9B" modified="2018-01-31" version="1">MKTNAYAAQNATNPLAPFNFQRREVGQHDVQIEILYCGVCHSDLHIVRNEWQNTAYPCVPGHEIVGRVIKVGAHVKKFKEGDTAGVGCMVDSCRTCANCEEDLEQFCDNITFTYNSPDKHLGGMTFGGYSDSIVVDEAFVLQVPQNLNLAAVAPLLCAGITTYSPLRHNNVTKGQKVGVVGLGGLGHMGVKLAKAFGAHVVVFTTSPNKVEDARRLGADEVVNSKNADEMKKHLNSFHFILDTVSAQHDINAYLLLLKRDGNLTQVGVPAEPLSLNVGSLIFGRRSLSGSLIGGIKETQEMLDFCGKHNITSDIELIPIQNINQAYDRLVKSDVKYRFVIDMASLQEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F457</accession>
    <name>A0A2G4F457_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56528">
        <property type="protein sequence ID" value="PHX56528"/>
        <property type="gene ID" value="CP500_004915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="124" mass="14225" checksum="03F84668B998F63C" modified="2018-01-31" version="1">MSPTSISRYVTRNPEVLQGEPIIADTQVTVRDIVVFWKSGIKPEEIPQKLLQLVTAAQVFDAISFYLDNQPEIDDRIAWYEARPMLNVSPLLRCNPLLNEVTEYVAAYRRDRNADINFLESEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F490</accession>
    <name>A0A2G4F490_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_004515</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56603">
        <property type="protein sequence ID" value="PHX56603"/>
        <property type="gene ID" value="CP500_004515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="3"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="139"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="173"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="207"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="240"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="274"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="390"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="424"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="458"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="937" mass="105815" checksum="805BBFA86659D0A8" modified="2018-01-31" version="1">MSIQEYIRLAQGYLAQGKWTEAIANCHQWIKLQPDSAAAYTTLGEAIEAGGDVNEAWRSYLKALEISPLFVRAHVCLGLLYSEYNWLDEAVVHYQQVLEIKPNWAELHYNLANVFHKQGNLTAAIDSYRNAIALKPNYADAYYNLGVLLNENNQLEAAIDAYEEVIAIAPNYLKAYSNLGCVLVKQEKAQEAIAIYERAIAIKPDWATLYNNLGQVLLDKNPDRAIAAYHKAIELEPDLVLAHYNLGKAWQIQGEHSVAVVCFDRVVELNPDYISGYTDAGFSLMALGKIAEALPYFAKAIALKPDFVEAYCDLGESQNFAQDDDDEFSKAIAACGRFLQALTGRKFGNGLCNGFNGFKRITNFQFPMPDAQFPMPDFQLEIGEICDNLAEIYWHLGNALTEYGGYEAATAYYQKALQIQPKNTELYSRLGNSLVKQKRLDAAILVYHMALAIQPAQPQVYFELAKVLERQGSLERTLDYYQKVLELQSHGYSQPQLSKQNHGIEFALNAIELPQGIYLSTWDWLVAAKLNAGNYVEIVWKYAPEASTENIPNAQCPMPNAQCPMPNSDCGGLTCGLCLQRLSKWFDPIHLGWGVCRLSNSQPLPVESPKTFVAAIPDGRVWIVPQENYWLICKAIAVITPDNYLLADVSRDYPGFLPGCERHDVRKHSVFNLESFPPLKQIEGSVAVLSGLSGNVYFHWMVDVLPRIELLRRSGRDLTEIDWFLVNSCQHQFQRESLRILGIPEEKVLESDRLPHIQATELIVPSFAGYLGWPSGWAIDFLRREFLKGIIPSYNYPKRIYISRSKARYRRVLNEADVVEVLEGFGFVSILPESMSLLEQIAYFYHAEVIVAAHGSGLTNTIFCQTGTKVIELMSPHYISHYYWGSSQYLQLEHYFLTGEAFECYPIRQLMYQNSLTEDILVNLSSLKRMVEVVGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4A1</accession>
    <name>A0A2G4F4A1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Agmatinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">speB</name>
        <name evidence="5" type="ORF">CP500_004585</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56614">
        <property type="protein sequence ID" value="PHX56614"/>
        <property type="gene ID" value="CP500_004585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="309" mass="34166" checksum="6691DD77138578AB" modified="2018-01-31" version="1">MPTIISTAVVPFLGSEIVPDYHTAKVVILPIPYEATTTYRRGCENGPAKLLEASHQLECYDEELDSEVCYDVGIYTKEPIADTRNSQPVSSLEMLQVTQAAVYQLVTENKFVISLGGEHSITAGVVEGYRQAYPDEAFTVIQIDAHGDLRHEYEGSIHNHACVMRRVVDMGLPTLQIGIRAICKEEADLIKAKQLNVIRAREIANEPDWADRAIASITTKRVFLTIDLDGIDPTLIPGVGTPEPGGLNWYSLTGFLRRVFQSYEVIGCDIMELAPVVDSVVSEFTAAKLTYKMIGYQALAQGWLKQGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4D7</accession>
    <name>A0A2G4F4D7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56347">
        <property type="protein sequence ID" value="PHX56347"/>
        <property type="gene ID" value="CP500_005750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="16714" checksum="37EBC201544CDEC6" modified="2018-01-31" version="1">MEDWSKEFFEVMENAASEVEHFFSDMNEEFAEMVDVLVKMSEEFTQQIQNNLIDDIDGYFSEFDGYLNELIEPIIEVYRDFDSNIGDIDSSFVTYVDPSPTQHPACRGCSNYHGQVYGGNLLVCAIHPTGVESESCADWESDGDADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4N3</accession>
    <name>A0A2G4F4N3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56744">
        <property type="protein sequence ID" value="PHX56744"/>
        <property type="gene ID" value="CP500_003800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041669">
        <property type="entry name" value="TetR_C_15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17918">
        <property type="entry name" value="TetR_C_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="21"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="223" mass="25250" checksum="DA039F8436DC0DF9" modified="2018-01-31" version="1">MAVNSSKSSGMRRQPRQARSQERVNQILDVAEQMFITEGYNATTTNAIAATAKVPIGSLYQFFPDKAAILQALTMRYMELLHQRFTELKTAETDNLPLSTYVDRMIDATDRFFIDHPGYHAIFMQVQGTMPELEAIETAADAQLIEDLATFLSLRNSNVEKTNYEAIAFVLVKAIGTLLWLALSEEQPFRQQLVTETKRLTLSYLQSYFSSSEIPLESSKTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4T1</accession>
    <name>A0A2G4F4T1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56748">
        <property type="protein sequence ID" value="PHX56748"/>
        <property type="gene ID" value="CP500_003820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="11933" checksum="4607AF230E10A570" modified="2018-01-31" version="1">MVELNWHDYVVMVSFVASIVGLVLLGDRKSQPTDDRTFSEETLIKMSFIYSIVYSISVLGLKIPLPEDHWLLASLKLTTVLSYLLTFSSILSLPLQRMAVRQVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4W0</accession>
    <name>A0A2G4F4W0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Filamentous hemagglutinin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56833">
        <property type="protein sequence ID" value="PHX56833"/>
        <property type="gene ID" value="CP500_003280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008638">
        <property type="entry name" value="Filamn_hemagglutn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05860">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00912">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01901">
        <property type="entry name" value="adhes_NPXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013935447" evidence="1">
        <location>
            <begin position="26"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="domain" description="Haemagg_act" evidence="2">
        <location>
            <begin position="30"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="932" mass="94487" checksum="0401E9D3879ACEE3" modified="2018-01-31" version="1">MSHKTQVKIFCILFYVCGFPNLAIAQIAPDRTLPLNSTVTPNDNNFTIEGGTAAGRNLFHSFREFSVPTGGKASFNNIDTVQNIFSRVTGGSISNIDGIIEAKGTANLFLLNPNGIIFGPNASLNIGGSFLGTTANSINFADGTSFSATNPQTTPLLTISIPIGLQFGQNPGQIVDQSRAINSSGKVVGLQVLPGKTIALAGGDVKLDGGNLQAPGGRVELGGLSRSGTISLNWDNNQLSLSFPEGVARGDVSLTNGAIVDVRAGGGGIIAIATDNLNLAEGSMLLAGIRSWVSTAGNRAGNIQINATGAISFDGVGNDESSGAYNLVEFNAAGEGGSINITADTLSLTNGALIKASTFGQGNAGDVNIRIGNSTSLDGAGSNNISSGIYSRTEVKETIGNGGNINLTTGSLLLTNGGLITASTQGQGNAGNIVLSVSNQTILDGLGPLQEITLDGKLLQFQQSSGVYSSVKLTGVGNGGNINLTTGSLSVTNGAVAIVRTEGQGRSGNIVVNAADFVNIDGVGPDLSSSGLFAPTESKGTGQGGDIIVNTNNFRVSNGAVVNAQTLNDNAGGNITINANRFEATGGGQIIATTASSGQAGNLTINAADKVLISGSDPNFVQRVPLFSTNILGNNEGSPSGLFASTGKDATGAGGNLSVQAGRLIIQDGAKVTVSADGSGAAGNLIVNADSIRLDRGEISATTSAGNFGNIRLQSQDLQMRRSSQITTSATGSATGGNISIDTGALVALENSDISANSQEARGGRVTINAQGIFGTEARSQQTLNSDITATSLAGPQLDGEVILNTPDIDPTQGVVQLPKTIVNPDAIAQICPNQRQSGTDKTFTRIGRGLPANPAETPSNSSTAVGLADAVAPVEQRTRTAPRQQVGPPNRPILSAQGWAINTKGEVIFTANPATVTLQSPVQPTGGCYGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4X1</accession>
    <name>A0A2G4F4X1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56800">
        <property type="protein sequence ID" value="PHX56800"/>
        <property type="gene ID" value="CP500_003485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="274"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="223"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="494" mass="54583" checksum="8B5CF10CEBCF83EC" modified="2018-01-31" version="1">MTHYYGNYSSRSDLSDGEILQKTAEISPSQPLIGDRENQSDRHLDEIPHRFNASETAEKLGPTNAVREAQQLHLQAIERFTNVLNQRAGSWCELVQAIADTVVETIASAQFCLVALAECDRSSLKLSAVTGVENFALGRTLYVQNALLSQVFATGKSQLSSQESGAAMPTACAVAIESSLTGRLGVLALGNWQDSQAIDDATVQLLAVMGRQAAIAIHNARAIEIAKKQEQLLELQNQLLLRQQTELENQRLRLQQQHLQLLEAAKLKAQFLRTMSHELRTPMNAIIGFSELLLRQEKQMLTAQQKDFVGRIFKNGKNLLVLINDILDISKIETYPTELEIAEFDLAQLVIATALELGNQVTDKNLALSVSVCLQDRLIVNDKSRLRQVLVKLISNAIKFTHQGNICISVRELTLDRLTIAVTDTGIGITETELPHIFDKFHQADRATTRQYPGIGLGLAISASLARMMDGTLTAQSQVGKGSTFRLELPRQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F546</accession>
    <name>A0A2G4F546_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56923">
        <property type="protein sequence ID" value="PHX56923"/>
        <property type="gene ID" value="CP500_002795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="214" mass="24182" checksum="EAEF971E93DCFC22" modified="2018-01-31" version="1">MRSDIQGLEITVGELKRLSGATPDRVYRPATATKFAHEGLKTVGLMFLVLISCLLLVMIFPRAYLVWFIIHLTAIVGLIVEDAWKIRCSSQNKHLINLFDDVDRYNGIIKTIQINDQIEEAGNSQVKIGDRTKLIKALQLIRDDLVRALKTERILRENKKFVATNSELFSNNLTALSRLQISDRASQPGRLLNEALQLALGVQAEMKKLQNRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F558</accession>
    <name>A0A2G4F558_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_003190</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56890">
        <property type="protein sequence ID" value="PHX56890"/>
        <property type="gene ID" value="CP500_003190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="5">
        <location>
            <begin position="84"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="432" mass="47022" checksum="DCBB05AB8073FBC0" modified="2018-01-31" version="1">MTQATRTQSTAATFTALKCKECGEEYELQAKHVCDCCFGPLEVKYDYDAIRRTVTRQTIEAGPNSIWRYRAFLPVATDNVIDVGTGMTPLVKSHRLARRLGLKNLYIKNDAVNMPTLSFKDRVVSVALSRARELGFTTVSCASTGNLANSTAAIAAHAGLDCVVFIPSDLEAGKVLGTLIYNPTVMSVHGNYDQVNRLCCEVANTHGWGFVNINLRPYYSEGSKTLGYEVAEQLGWKLPDHIVAPLASGSLFTKIYKGFKEFVEVGLVDDKEVRFSGAQADGCSPIAQAFREGRDFVTPVKPNTIAKSIAIGNPADGMYALEVARKTGGNIESVSDTEIIEGMKLLAETEGIFTETAGGTTIAVLKKLVEAGKINPDETTVAYITGNGLKTQEAVQGYIGEPITLEPKLEAFERALERARTLERLEWQQVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F591</accession>
    <name>A0A2G4F591_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RHH_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56954">
        <property type="protein sequence ID" value="PHX56954"/>
        <property type="gene ID" value="CP500_002910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012869">
        <property type="entry name" value="RHH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07878">
        <property type="entry name" value="RHH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_5" evidence="1">
        <location>
            <begin position="6"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="58" mass="6714" checksum="78D4EDE9C4E4F49D" modified="2018-01-31" version="1">MASRGRVTAYLPEEIQKALEEWAEEDSRSVSSLATYLLTKSVRERQEQKKDKSESDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5A8</accession>
    <name>A0A2G4F5A8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplA</name>
        <name evidence="8" type="synonym">rpl1</name>
        <name evidence="10" type="ORF">CP500_002985</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56891">
        <property type="protein sequence ID" value="PHX56891"/>
        <property type="gene ID" value="CP500_002985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="237" mass="25785" checksum="BD9564453D58C1B1" modified="2018-01-31" version="1">MAKKVSRRLQELLKKVEDRPYLPLEALQLLKETATAKFAESAEAHIRLGIDPKYTDQQLRTTVSLPKGTGQVVRIAVIAKGEKVKEALNAGADIAGSEELIEQIQKGMMDFDCLIATPDVMPLVAKLGRLLGPRGLMPSPKGGTVTADVTQAINEFKGGKMEFRADKTGIVHVMFGKAAFSAEDLLINLHALQETVDRNRPSGAKGRYWRSLYVSATMGPSIEVDVSVLRDTKLDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5K0</accession>
    <name>A0A2G4F5K0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57040">
        <property type="protein sequence ID" value="PHX57040"/>
        <property type="gene ID" value="CP500_002305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="6975" checksum="DA61C99AE5DEB77C" modified="2018-01-31" version="1">MNPTIAFIFGLPLGRMKQPCRLLGTDVELTPKCRVEQDAVSAIGIQGDVNICNILRNTTDRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5L5</accession>
    <name>A0A2G4F5L5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNHc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57093">
        <property type="protein sequence ID" value="PHX57093"/>
        <property type="gene ID" value="CP500_002105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025960">
        <property type="entry name" value="RVT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13655">
        <property type="entry name" value="RVT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="344"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="411" mass="46893" checksum="7565CD37CA5CF709" modified="2018-01-31" version="1">MNKSKTRDNPTVEWNQINWRKAERLTFKLQKRIYRASERGDVKAVRKLQKTLINSWSNKVLAVRRVTQDNTGKRTAGVDGIKLLTPKQRLKLVSQLKITGKSQPTRRVMIPKPGTNESRPLGIPTMYDRTLQAVAKAALEAEWLSDLGLELKPSKTKLTHTLNEYNGNVGFEFLGFHVQQHKVGNYRSAKSTNGATLGFKTLITPSKPKVKTHLAKIEEVIDTHNTAPQAGLISRLNPIIKGWSNYYSTVVSKDTFSRIDHLTYDKLRAWARRRGKGSINKDKYWRTVGDRNWCFSTEEGLELTQHQATPIIRHVKVKGNSTPYDGDWIYWSKRRGEYPETPTRVATLLKAQKGKCTHCGLYFTPTDTVEVDHIQPRSLGGKDEYKNLQLLHKHCHDTKTENDGSLNKKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5W0</accession>
    <name>A0A2G4F5W0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsS</name>
        <name evidence="6" type="synonym">rps19</name>
        <name evidence="9" type="ORF">CP500_001795</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57174">
        <property type="protein sequence ID" value="PHX57174"/>
        <property type="gene ID" value="CP500_001795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="93" mass="10374" checksum="83639731B3F56D11" modified="2018-01-31" version="1">MSRSLKKGPFVADHLMTKIEKLNAAGQKQLIKTWSRASTILPQMVGHTIAVHNGRQHVPVYVTDQMVGHKLGEFSPTRTFRGHAKSGDKKAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F601</accession>
    <name>A0A2G4F601_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_001275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57186">
        <property type="protein sequence ID" value="PHX57186"/>
        <property type="gene ID" value="CP500_001275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="3">
        <location>
            <begin position="88"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="539" mass="58482" checksum="1957E6C542FF05A2" modified="2018-01-31" version="1">MAKSALMAMLRRASIIAQKSMATGIPADELLEMLNDRTSNFPISRRGLLQGGLATGAAVAAATLTREGEGAFAQQQGRSPILVVGAGIAGLTAAYRLRQRGVRADIIEATNRVGGRIRTMPKVAGTLISADVGGEFIDSGHTTLISLATELGLRAIDLVEAQRGLVKDTFFLGGRRYSLQQLITDFAPLATKIRADLRAIGKNIDYQDFTETAEKLDNLSIAEYVEGAETSVIVKQLLRIAYTTEYGRDADEQSALNLLFLIGAKAESFELYGDSDERYQIEGGNSQIVNSLAGQLSGSIEAGTALEAISILPDGRYRVSLRSGQSTFDRTYERVLLTLPFSTLRDVKINVPLSQSKRRAIEQLGYGTNSKLVTGYRSRIWRDLYRSTASVYTDLGFQNSWEATPFTPAINGLVTNFTGGRQGLAIGSGIPEDQAQKFLGQFEKVFPGVKDLRSGKAVRAFWSGERYFKGSYSCYLVGQWTQMHGVEGEQVGNLYFAGEHTSLENQRSMEGGCETGQRAAGEILKDLGLTASANALNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F679</accession>
    <name>A0A2G4F679_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chemical-damaging agent resistance protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57249">
        <property type="protein sequence ID" value="PHX57249"/>
        <property type="gene ID" value="CP500_000995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06974">
        <property type="entry name" value="TerD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003325">
        <property type="entry name" value="TerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02342">
        <property type="entry name" value="TerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TerD" evidence="1">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="188" mass="21354" checksum="F0CC9009144A018F" modified="2018-01-31" version="1">MAMQLTKGARFNLSKEAPDLKKMAIALGWQVTEAGQSYDIDVSAFMLGADGKIPNDQYFIFYNNLQSYDSSVLQSIPDKNNRSQENKTIYGIILERVNPEIEEITFVVTIHEADKIKANFSNIKNAFIKISNLDTGSELVRYELTENFSRETAVEFGRLYRKSGEWRFQAVGEGYQAGLQSFVDKYCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6D5</accession>
    <name>A0A2G4F6D5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57332">
        <property type="protein sequence ID" value="PHX57332"/>
        <property type="gene ID" value="CP500_000700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="98" mass="11024" checksum="EA911BEDF449EA0B" modified="2018-01-31" version="1">MSERIRFHLDENVKSAVARELRRRLIDVTTTIEAGLLAESDESQLAFICEKKRVIMTHDDDFLTIASLSSEHPGIAYCKQGTCSIGQIIEALVLIYEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6H7</accession>
    <name>A0A2G4F6H7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57358">
        <property type="protein sequence ID" value="PHX57358"/>
        <property type="gene ID" value="CP500_000535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BON" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="1087"/>
            <end position="1201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1201" mass="134197" checksum="88AEB88496F390D6" modified="2018-01-31" version="1">MAKFNVDSGEMKQVEIVESDATNSAIPKASEQLQELMNMLAELQLLKFKKESNKLDLRCIEMSKNKNEGQETGQNQHLSFLIEPPAIVPEILNEEREIAVRKKVDEERVSSRKAQLKKDDLPSEEELEKAVDKFKRLQQLLFERDLPEFYDNVLSVEQRLTNFEKLIADPDELLKLLTPLIPELLSGQVRELKSELREAIAPDGSLRINQSEVEAKVVELQNQIAMLSQQRTPNAEELIKGLIPIISDLLSRKLEESKLDVDSTIVPAVNEVINHQNGLEEKVLNIENQFANFRQRFQHQPEDIVKQLLPIISDSLNRKISELKSELIDAVTPSAQVRIAWVEVEEKVLNIIEERLIGQQPQIQKPEEIISRVMPVITELLNGKIEESKLELAAVIEALMLGKSHQEAIQVQLLNVENKFNILQRKQNSQPEEIMARLMPLMIESLNRKIDETKLEVREAIAPGIIAAFQNSGIEAQILRNEHQIVEFQQQTIAELEGLMARIMPGITQILSDKISEARLEIESAIAPTVDAIIQNKRIEERLGKIEQKIVAIEHRIYESTDLFTDLLKPLIDELMVGHHKQLEQSVIESILPLLDEVVNYNYQLNDKVVNLERQLNNAEWGGNDEALVAKIKAIFLEMMLETINESREAFTETIAPIIDQVINTKTRENPHSMGVAISPAIPVGISQRITESPDEIAQALAPEMASAVRQQINLNREAMSDALYPIIGSTILKYIAETMQEINEKVEQAVSVEGITRKVKARLQGISEAELLMKETTPSTVKAVFLIQKDSGLVVAEVQQSEQEQLESEMVAGMLTAIRSFVNDCISQSGNIAEIDAIEYGTSTIVLEVAGSCYLAVVIQGETRQWFKYKMRAIFKNLVQEYGNKIQSFNGDPTSIPVEINSELRKLIDTDVKVKSSKPKPLLILGLAALGLIVVPWGIHQYRSGVEGRLEADTNLALQSAPELSVYRLNADVKGKVAQLSGRVPNQKMRLRASQIAQKVVPQLTVENKIIAVEVPPDPVLVEADVKRTAALLNKVEGINISTRYAGDKVTIEGSVSRSTDAQKVTEAFAKIPGVKSVTNTVGIGTKPLSKAMEIQIYFGVGGASLSPKDVTQKINKVQEFMAANKGKNLRIVGYSDFKSNPGENQRLALERAKNVKVALVNKGIDGDRIQVASTKSRPEGVAENQPLWLRRTVIFEVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6J1</accession>
    <name>A0A2G4F6J1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxythreonine-4-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.262</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-(phosphohydroxy)-L-threonine dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pdxA</name>
        <name evidence="5" type="ORF">CP500_000540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-(phosphooxy)-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32275"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="EC" id="1.1.1.262"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="4">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="4">The active site is located at the dimer interface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PdxA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.262" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57359">
        <property type="protein sequence ID" value="PHX57359"/>
        <property type="gene ID" value="CP500_000540"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00312"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050570">
        <property type="term" value="F:4-hydroxythreonine-4-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00536">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037510">
        <property type="entry name" value="PdxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005255">
        <property type="entry name" value="PdxA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30004">
        <property type="entry name" value="PTHR30004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04166">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00557">
        <property type="entry name" value="pdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="351" mass="38017" checksum="AE6C711A56E878AA" modified="2018-01-31" version="1">MLDRGLKLAVTLGDPAGIGPEVILKALADPVEASGAWTIGSRTILQQTYEKLRSLDPSVALANPDTLNIIDVETDSKWGEIIPGVGNAASGAASFADLESAIARTLAGEFSAIVTGPISKTCWQAAGYNYPGQTELLAEKARSKRFGMLFAAKSPHSNWMLITLLATTHIPLRQVPDALNPDLLTEKLELLIECLREDFGLETPRIAISGLNPHSGENGKLGNEEQDWMIPWLATQRDRFSQVQLDGPIPPDTLWVKPGKAWYGLAEPAHDAYLAMYHDQGLIPVKLMAFELAVNTTIGLPFVRTSPDHGTAFDIVGRGIADASSMKSALELARELARRRSIVKLGRSAKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6N4</accession>
    <name>A0A2G4F6N4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57432">
        <property type="protein sequence ID" value="PHX57432"/>
        <property type="gene ID" value="CP500_000410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="199" mass="22025" checksum="3095F795F4452268" modified="2018-01-31" version="1">MAYSEFKLKELVKKFDLTLNENQDLFAHISEVESSEILKVALKENAGLAVDINTEKARSELIIAPILLEVRRQLNYQIGLFSGSEFNVAPEKGLNGTCDFLMSLSAERLFISAPVIALVEAKKEDIKAGFGQCAAEMLAAQLFNQEEGNQIPVIYGAVTSGTVWRFLKLEGKIVDIDAIEYYLRDIGKILGILLSAIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6T2</accession>
    <name>A0A2G4F6T2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57445">
        <property type="protein sequence ID" value="PHX57445"/>
        <property type="gene ID" value="CP500_000475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="200" mass="22158" checksum="F422A8D21046040A" modified="2018-01-31" version="1">MAYSDFSLEGVVKKFELKYSEVADLFAKEHKLECSQLLAETLKRSVPLALASNTDKSRAEMITTPILIELREQLKNRISLFSGIDFNVDSEKGLNGSCDFLIGNSSGLLFVDAPVIIIVEAKPENLNSELGQCVAEMFAASIFNEREGNEIPAIYGAVTSGTNWKFLRLKDQVIEIGLTEYYITDVNKILGILASVIDRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F739</accession>
    <name>A0A2G4F739_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Energy-coupling factor transporter transmembrane protein EcfT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_000375</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57427">
        <property type="protein sequence ID" value="PHX57427"/>
        <property type="gene ID" value="CP500_000375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="331" mass="38085" checksum="44A78D8A08170909" modified="2018-01-31" version="1">MDLLRSLPIGLYLEQPVTWLHRLDSRVKLAWLMTFLIAPILANPVWRLMLVGMLIILTLTAAIPLRVWKQQMGLLLLFCCLVFGLSAIAPDALPSEHQPRLPADELAFSQQPTTLPKATPPKPWYQPFNLDSKSQTQNPKSKVQNSLPQPTNYSYVLFKQGPIKITRKSLDLAINVSTLFFTVIYSTNLYLLTTASEEITTAIENLMQPLRRFNWPVTEIALTLTLSLRFIPLVLEEIQNLVRSVRTRAINWKKLGFRRAAQVWLMIAERLLENLLLRAEQIASAMKVRGFTSPDRHRVEWHHLHLKIRDWIAIGCLIVLWSARLVWGWDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUC6</accession>
    <name>A0A2G4EUC6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_023125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000268">
        <property type="protein sequence ID" value="PHX53135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53135">
        <property type="protein sequence ID" value="PHX53135"/>
        <property type="gene ID" value="CP500_023125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="137" mass="14909" checksum="5ACF0138F2BAD244" modified="2018-01-31" version="1">MSEIPAEQTPTNLPTPETTTESSISAVDNVKNTLGNILNSWKLKVGLAVAVVFAVLLLAFYWQHIIAVVGMKSWSARSGAKPIECMVRDTNNDEYVSCSALLDQQIVPLECSSSLFNIGCRVNYGTAAPNPRKINPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUS7</accession>
    <name>A0A2G4EUS7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphorybosylanthranilate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BtpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000220">
        <property type="protein sequence ID" value="PHX53302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53302">
        <property type="protein sequence ID" value="PHX53302"/>
        <property type="gene ID" value="CP500_022240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005137">
        <property type="entry name" value="BtpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21381">
        <property type="entry name" value="PTHR21381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03437">
        <property type="entry name" value="BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005956">
        <property type="entry name" value="BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00259">
        <property type="entry name" value="thylakoid_BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="295" mass="31358" checksum="5C3963CF920011E1" modified="2018-01-31" version="1">MDLKQIFKTPNPIIGVVHLQPLPTSPRWGGNLKAIIGRAEQEATALASGGANGIIVENFFDAPFAKDRVDPAVVSAMTLIVERLTNLVTLPIGINVLRNDAHSAIAIASCTGAQFIRVNVLNGTMATDQGLIEGQAHQLLRYRRELGSDVKILADVLVKHGQPLGSPNLRTVIQETIGRALADAVILSGPTTGSPPNLEELELASIAAAGIPVFIGSGASWENISTLMRAADGVIVSSSLKRNGRIDGPIDPIRVSQFVEAARRSLSEKERQHENSEANGSHGLVSELDKLKSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUV0</accession>
    <name>A0A2G4EUV0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000234">
        <property type="protein sequence ID" value="PHX53236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53236">
        <property type="protein sequence ID" value="PHX53236"/>
        <property type="gene ID" value="CP500_022580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7444" checksum="7533F06A57AA73E6" modified="2018-01-31" version="1">MGVLFDTPKFFVENDFRVTVNSQQSTVNGEQSTVNSQQSTVNGEQSTVNRQPETIQITLLGDARKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUW1</accession>
    <name>A0A2G4EUW1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b6-f complex subunit 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytochrome b6-f complex subunit PetL</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytochrome b6-f complex subunit VI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">petL</name>
        <name evidence="10" type="ORF">CP500_022500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 9">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PetL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000230">
        <property type="protein sequence ID" value="PHX53246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53246">
        <property type="protein sequence ID" value="PHX53246"/>
        <property type="gene ID" value="CP500_022500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009512">
        <property type="term" value="C:cytochrome b6f complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045158">
        <property type="term" value="F:electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00433">
        <property type="entry name" value="Cytb6_f_PetL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007802">
        <property type="entry name" value="Cyt_b6/f_cplx_su6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05115">
        <property type="entry name" value="PetL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="33" mass="3505" checksum="69C4CEBEF3432F1B" modified="2018-01-31" version="1">MTLSGIITYFGLFGGMLGLATVLMFGLRAVKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUW4</accession>
    <name>A0A2G4EUW4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chemical-damaging agent resistance protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000224">
        <property type="protein sequence ID" value="PHX53278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53278">
        <property type="protein sequence ID" value="PHX53278"/>
        <property type="gene ID" value="CP500_022350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06974">
        <property type="entry name" value="TerD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003325">
        <property type="entry name" value="TerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02342">
        <property type="entry name" value="TerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TerD" evidence="1">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="189" mass="21042" checksum="5582556A93306B75" modified="2018-01-31" version="1">MSINLEKGGRINLSKEAPGLKSAGIGLGWDTNATDTGAEFDLDASVFMLGANAKIPSEKYFVFYNNQESPDSSVKHLGDSRTGEGADDDETVTVDLTKVDPAVQEIVFVVTIHEAESRRQNFGQVRNAFIRIYDTTTNIEVTKYDLDEDFSRETAIEFGRLYKKDGEWRFQAVGQGYNSGLQSFVDKYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUW5</accession>
    <name>A0A2G4EUW5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutamyl-tRNA amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000215">
        <property type="protein sequence ID" value="PHX53324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53324">
        <property type="protein sequence ID" value="PHX53324"/>
        <property type="gene ID" value="CP500_022120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="PTHR28055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="152" mass="16890" checksum="FBB6C014B6414CAF" modified="2018-01-31" version="1">MSLKERIDAEIKAAMKSKDKVRLETVRGIKKFILEKEVSVRPSGQEGLTEAQEMEILVQIAKQRRDSIEQYRKGGREDLVAQEEAELVILEEYLPQQMSDEEISGVIDEVIASAGATSAKEMGKVMGAAMQQLKGKADGKKIQDMVKAKLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV03</accession>
    <name>A0A2G4EV03_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2157 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000208">
        <property type="protein sequence ID" value="PHX53369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53369">
        <property type="protein sequence ID" value="PHX53369"/>
        <property type="gene ID" value="CP500_021875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018677">
        <property type="entry name" value="DUF2157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09925">
        <property type="entry name" value="DUF2157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2157" evidence="2">
        <location>
            <begin position="16"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="466" mass="52092" checksum="FA78E356D3BD85D7" modified="2018-01-31" version="1">MISDQFRRELRSQAKLWEAEGLIDTSLYQQLADRYQFNTLETASRNRFLSILISLGSILLAIGVITFVAANWQVWSREARVTLLLSLFVAVNIAGFYLWRIPPSRSTNSNQNMPPTKGRNKLLGEGLLLLGALILGANMALMAQMFHIGGSSYGLFLAWGIGVLGMAYSLRLTSLGVLSALLVGLGYWLAVLDFSSKVEFSWLEVLVRQMPIAASIMFIPLAYWCRSRAIFAIGAIVLIFSLQVSIAQGLNPNWGVTIFCALPPALLWGYDDAMWPNIDSRLFQPTARSLALIFLAGLFYFLSFHWLWQDSPAPSQIPLDWSVLTNLAVLGALTVFEWLHLGRLELRQPKRKGVDLTTGAIGFFIVITALIPFYHINFSPLPQLATFLFNVLLFLLAVGLIREGLALGKRQTFWGGMVLITLQIISRLFEYNTELLLKSFVFVLCGIGVIAAGLWFERHFATIKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV27</accession>
    <name>A0A2G4EV27_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Molecular chaperone HtpG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_022175</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000217">
        <property type="protein sequence ID" value="PHX53316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53316">
        <property type="protein sequence ID" value="PHX53316"/>
        <property type="gene ID" value="CP500_022175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="SSF110942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c" evidence="5">
        <location>
            <begin position="27"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="662" mass="75536" checksum="407C0A937BEC915D" modified="2018-01-31" version="1">MTVLEQGTISIHTENIFPIIKKSLYTDHEVFLRELISNAVDAIAKLKMVSRSGEYSGDIGEPQINIAIDKENKTLSITDNGIGMTADEVKKYINQVAFSSAEEFIQKYQGSGEDAIIGHFGLGFYSSFMVAQKVDIDTLSYQEGAQAVHWYCDGSPAFELSESTRTERGTTITLTLQDEELEYVEATRIKQLIKTYCDFMPVPIKFEGEELNKHKAIWRESASNLQKEDYLELYRYLYPFQDEPLLWVHLNTDYPFIVNGILFFPKLRPDVDVTQGNIKLFCNQVFVSDHCEEIIPKFLMPLRGVIDSTDIPLNVSRSSLQSNRTVRRIADYIAKKVGDRLKELYRDDRNEYIRCWQDIGTFVKFGTLNDDKFKKQVEDILIYRSTYQPTVEKSETVTPEVQVQTEDGDLWQDVNPKSETSGSTQPYTTLKEYLERNQKTHENRVFYCTEPASQATYVALHKSQGLEVLFMDSFIDTHFISFLEREYSDVKFSRVDSDLDDTLIDKEKEAEIVDPTTNKTRSEQVKELFQKAIGKPKVNIRTEALKSDVAEAAPPAIVLLPEALRRMRDMTALLQQQVAEFPEEHVLLVNTAHPLIQNLANLSQGAIIQGEGESPSAELASMICHHVYDLALMAQKGFDAEGMKEFVERSNQVLTKLTERAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV51</accession>
    <name>A0A2G4EV51_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000200">
        <property type="protein sequence ID" value="PHX53422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53422">
        <property type="protein sequence ID" value="PHX53422"/>
        <property type="gene ID" value="CP500_021585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="225" mass="25469" checksum="C9012F8F199FA215" modified="2018-01-31" version="1">MVKNSNNLQKGSIWGYLTLLLPISLTAVASFESGGMFWAIAATAGMAGAYKLYHQHQKHQLAHLDSVFYRLIKENKGRVTALDLAMNVKLPGSKVQEYLDERASEFAADFEVTEQGGILYYFQVAPNVNQSEVIPVKIAVKAPEINQKQVSNKNPELFPITQKNRAANPKISFTQTELSRRFKVHASTIGKWKVKPEFGDWSREKDPDAIAWEYSTENKRFYPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVH3</accession>
    <name>A0A2G4EVH3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000192">
        <property type="protein sequence ID" value="PHX53478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53478">
        <property type="protein sequence ID" value="PHX53478"/>
        <property type="gene ID" value="CP500_021305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="9"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="9562" checksum="2E25BA10D6383FCC" modified="2018-01-31" version="1">MQIPENPSNDDIRESLIQLREALIQLREELGQKVDRLEYKFDAYQKGTDGMVRMATTIIIATASVVVLSSLSPAVTAIVTALSAGNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVI8</accession>
    <name>A0A2G4EVI8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,4-alpha-glucan branching enzyme GlgB</fullName>
            <ecNumber evidence="9">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Alpha-(1-&gt;4)-glucan branching enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glycogen branching enzyme</fullName>
            <shortName evidence="9">BE</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glgB</name>
        <name evidence="12" type="ORF">CP500_020930</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000180">
        <property type="protein sequence ID" value="PHX53545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53545">
        <property type="protein sequence ID" value="PHX53545"/>
        <property type="gene ID" value="CP500_020930"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02855">
        <property type="entry name" value="E_set_GBE_prok_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00685">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006407">
        <property type="entry name" value="GlgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044143">
        <property type="entry name" value="GlgB_N_E_set_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="PTHR43651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01515">
        <property type="entry name" value="branching_enzym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="11">
        <location>
            <begin position="283"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="764" mass="88509" checksum="D6952CD105C27752" modified="2018-01-31" version="1">MSATVPFEQIDRIVGNQHHDPFEVLGPHAIEQNGKKIWAVRVYLPNADAVSVVLPASRAEHPMQSVHHPHFFECAIETPELANYQLRVKEGEHERFIYDPYAFRSPKLTEFDQHLFSEGNHHRIYEKLGAHITQVDGITGVYFAVWAPNARNVSVLGDFNYWDGRKHQMRKSQNGIWELFIPGLDDGTHYKYEVKNQNGHPYEKSDPYGFQQEVRPKTASIVTDLNTYTWNDSAWIEKRRHTDPLTQPISVYECHIGSWLHAATDEPALLPNGDIEPSVQVSELKPGARFLTYRELADRLIPYVKDLGYTHIEVLPVAEHPFDGSWGYQVTGYFAPTSRYGKPEDFMYFVDQCHAAGIGVLVDWVPGHFPKDGHGLPFFDGTHLYEHADPRKGEHKGWGTLVFNYGRNEVRNFLVANALFWFDKYHIDGIRVDAVASMLYLDYCREPGEWLTNQYGGRENIEAADFLRQVNHAIFSYFPGALSIAEESTSWPMVSWPTYVGGLGFNLKWNMGWMHDMLDYYHMDPWFRQFHQNNITFSMWYNHSENFMLALSHDEVVHGKAHIIGKMPGDEWQKFANVRCLFTFMFTHPGKKTMFMGMEFGQWKEWNVWGDLQWDLLQFEPHQKLKLFFKDLNNLYRSESALYSQDFAEEGFDWIDCSDNRHSVVAFVRRSKDGKEFVVTVCNFTPQPHSHYRVGVPEPGFYTELFNSDAREYGGSNMGNLGGKWTDEWWFHNSAYSIDLCLPPLGVLILKIDRAKTSAKSQEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVP3</accession>
    <name>A0A2G4EVP3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2Fe-2S ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000186">
        <property type="protein sequence ID" value="PHX53510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53510">
        <property type="protein sequence ID" value="PHX53510"/>
        <property type="gene ID" value="CP500_021115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="11885" checksum="9543288111B4E7EF" modified="2018-01-31" version="1">MLESEAKKPESQHEARCILVCQHQSCLRNGSAAVLAAFEAHPVSGVKVEGSDCQGQCNMGPTVRVTPDEIWYCRVKPIDVPLIVEQHLLGGKRVKALFNPRIHLYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVS9</accession>
    <name>A0A2G4EVS9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable aspartoacylase</fullName>
            <ecNumber evidence="5">3.5.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_020435</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + N-acyl-L-aspartate = a carboxylate + L-aspartate</text>
            <dbReference type="Rhea" id="RHEA:10872"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:58497"/>
            <dbReference type="EC" id="3.5.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5 7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AspA/AstE family. Aspartoacylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.15" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000169">
        <property type="protein sequence ID" value="PHX53634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53634">
        <property type="protein sequence ID" value="PHX53634"/>
        <property type="gene ID" value="CP500_020435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019807">
        <property type="term" value="F:aspartoacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00704">
        <property type="entry name" value="Aspartoacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016708">
        <property type="entry name" value="Aspartoacylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018001">
        <property type="entry name" value="Aspartoacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="63"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR018001-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR018001-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="315" mass="35340" checksum="6B0677F9C43C8965" modified="2018-01-31" version="1">MNKIKRVAIIGGTHGNELIGIYLVNKFDRQPDLIARSTFQTMALLANPKACAIGKRYIDIDLNRCFLQQDLENPNLSSYESERAKEIYHIFSSKNRDDADLIIDLHTTTSNMGLTFILDSQHPFDLQLATHLTSVYPNFKVLASGTQNQDTSVLRSISKLGFTLEVGPVAQGVLDASLFQQTEALVGTILDWVEAYNQETIAPVENPLTIYQKVQTIDYPRNESGEIQAMIHPQLQFRDYEPLNPGDPMFLTFDGESLFYEGKSTVYPVFINEAAYYEKGISMYLTQKQIVIGNGEWGIGNGELGISNWELVIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVT6</accession>
    <name>A0A2G4EVT6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_020410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000168">
        <property type="protein sequence ID" value="PHX53644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53644">
        <property type="protein sequence ID" value="PHX53644"/>
        <property type="gene ID" value="CP500_020410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="27"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="322"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="416" mass="43720" checksum="82AAE9AD53CB54F5" modified="2018-01-31" version="1">MPNIKKISNIQIVFMATEALWNNKLRTSLTMLGVIIGISSVITITSVGQGVQKSTEEQLKALGTNVLLVLSGASRSGGVSQGGGSASTVTWDDARAIGKQAPAVKAISAFLQRQVQVVYGGQNSFTSILGTDLNYPDVKNIQPQAGRFFNEDELNAAEPVVVLGSKVRDDLFGVGANALSSDIRIQGNRYKVIGVMEPKGSVGGTDQDDRVYIPLKNMSARIVGRNSLAGIAISGFWLQTTGESDLADAQFQVENIMRLRHNIYPPQPDDFRVINQVDIVNTFSNVVGLFTVMVVAIAGISLVVGGIGIANIMLVSVVERTKEIGIRKAVGATNAAILIQFMAESILVSTVGGTAGIGLGIAIAFGAATAFSFPFVVSVWSIAAGFGLSFTVGLLAGVLPARNAARLDPIAALRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVZ5</accession>
    <name>A0A2G4EVZ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53357">
        <property type="protein sequence ID" value="PHX53357"/>
        <property type="gene ID" value="CP500_021975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polyketide_cyc" evidence="1">
        <location>
            <begin position="13"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="153" mass="17674" checksum="24DCBCE82A8A68BE" modified="2018-01-31" version="1">MPNFRYSSLINSAVETVWNFHERPDVLQLLTPPWQPVKIIRREGGLAVGAVSEFRLSLGPIPVKWVATHTECELYRLFVDEQTEGPMASWIHRHEFTTENGQTRLTDAIAFSIPGGPIVDLLLGWWVEIRLTDMFRYRHEVTKRECEKNVNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW03</accession>
    <name>A0A2G4EW03_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53732">
        <property type="protein sequence ID" value="PHX53732"/>
        <property type="gene ID" value="CP500_019920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="183"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="430" mass="49053" checksum="CE5D7A722B1AC466" modified="2018-01-31" version="1">MQLAERHIIKSTEHRFVEIDGLAFKSKNLYNAANYVIRQSFVYGWGYINYNEMNRLMKSHSAYKELPAKVSQQILMILDKNWKSFFEAVKAYKIDSTRFTDRPKLPKYKDKVKGRNILVYTIQAISSKELKKGIIKLSGTNILIKTQIKPERICQIRLVPKCDSYIIEVIYNACTEPESTLELDENPKELVASIDLGLNNLVALTSNQPGFVPLLINGRPLKSINQFYNKRKARLQSQLKGLRKTSSRIQRLTRCRHQKVDNYLHSASRYIINVLGSRNIGTLVIGKNAQWKNELDLGRKTNQSFVNIPHARLIEMLKYKAELMGIKIVEQEESYTSKSNFLNLDPIPVYGYIGTFDVTFSGQRIKRGLYRTSSGRLINADVNGSYNILRKAIPNAFSNGIGSCVVQPRRVNLLEVKAKGEGLNASHVMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW61</accession>
    <name>A0A2G4EW61_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">OMP decarboxylase</fullName>
            <shortName evidence="7">OMPDCase</shortName>
            <shortName evidence="7">OMPdecase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrF</name>
        <name evidence="10" type="ORF">CP500_020030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7 8">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the OMP decarboxylase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53696">
        <property type="protein sequence ID" value="PHX53696"/>
        <property type="gene ID" value="CP500_020030"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01200_B">
        <property type="entry name" value="OMPdecase_type1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119:SF2">
        <property type="entry name" value="PTHR32119:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7 8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="9">
        <location>
            <begin position="9"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="25519" checksum="B12A167455F9B089" modified="2018-01-31" version="1">MKDTTIADKIIVALDVPSQAEAIALIDKLPDVSFWKVGLELFVSCGPEIISILKQRGKRIFLDLKFHDIPNTVAGACRAAAKYNVDLLTIHSTCGKDALKAALVALESGAIAVDKPSPKLIAITLLTSLNSRQLAFELKVPLELPEYALHMALLAKETGLAGAVCSPQEVAQLRMSCGDDFLLVCPGVRPKWAEGGDQRRSMTPKAAINAGADYLVIGRPITASDDPVAAFARICEELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWC0</accession>
    <name>A0A2G4EWC0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_019220</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000148">
        <property type="protein sequence ID" value="PHX53852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53852">
        <property type="protein sequence ID" value="PHX53852"/>
        <property type="gene ID" value="CP500_019220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="351" mass="37578" checksum="B4E0EC5F151637DB" modified="2018-01-31" version="1">MPHHLFYHLLAFLVSAIVVLLSTPIVKTIGLKSGRVDRPGDRKVHQRPMVRLGGVSIFLGTIIALLIVWFSGGFIDASGQVLNPKDEYEIWGVTLGGIGFFLIGLADDLFSLSALKRLLMQTGVSSIAWYAGVQIEFLTVPSLGLTDLGWLSLPITVIWLVGMANAINWIDGLDGLAAGVSGIAAVVMLIVSLSMNQPAAALIAAALAGGTLGFLRYNFNPAQIFMGDGGAYFIGFTLAGVGVIGLVKTTAITSVLLPYLILAVPILDMSAVILDRLRNGKSPFIADKRHLHHRLLNAGLSHRFAVLFIYSLTLWVGSLALAFSVPSGIIYAMGATSLLGYASWKVWRHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWF5</accession>
    <name>A0A2G4EWF5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Clan AA aspartic protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000147">
        <property type="protein sequence ID" value="PHX53863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53863">
        <property type="protein sequence ID" value="PHX53863"/>
        <property type="gene ID" value="CP500_019185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="13781" checksum="F5D684AEA2E343AD" modified="2018-01-31" version="1">MITGIVNAEFEPIIPILICDSDGNVYTQDAIVDTGFNGWLSLSPDLIAQLNLRWKRRGRAILGDGSECVFNIYEAVVVWDGVYLTIPVDEADSEPLVGMSLMENYQLIVQVFEGGLVEISKVNMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWN2</accession>
    <name>A0A2G4EWN2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53962">
        <property type="protein sequence ID" value="PHX53962"/>
        <property type="gene ID" value="CP500_018735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="362" mass="40753" checksum="40385314224EA9D6" modified="2018-01-31" version="1">MDEIEYAKVYQELAAILNEFNLGWVAQQVADIVEIGKTMEERSLKRKTPLLKIVEYTPKEQLLMLIDAVEQATVHTSEMEDEIAYFLKVESETSPLGTKITFATSSAQSAQTIEFTSNLTAARNKQAIALKTLLDKLPSGPSNYLTNAEIKSKLSVAINPDFNGAIEQANIFDVYLFTILLKAIANEGGNIYYNNVLDETPKYLTFRKIAGKIHGNTHPYTYAVVEFPDKPAIEVHLGVKVQGRAGVLQNCNLLMLYQKEANICRLLNREPRHSQVILAVKSQHNTSELKLEMAGAFIGLASDIRYEGGSYFISNSYSEPVAKLLTIARKKWELNIFPRATNDVHRLMYSFQTIFKDFKARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWS8</accession>
    <name>A0A2G4EWS8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal peptide peptidase SppA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sppA</name>
        <name evidence="3" type="ORF">CP500_018475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000133">
        <property type="protein sequence ID" value="PHX53993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53993">
        <property type="protein sequence ID" value="PHX53993"/>
        <property type="gene ID" value="CP500_018475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004635">
        <property type="entry name" value="Pept_S49_SppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00706">
        <property type="entry name" value="SppA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S49" evidence="2">
        <location>
            <begin position="68"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="272" mass="30227" checksum="F2079408C97CD493" modified="2018-01-31" version="1">MIWPFKPRYRKQIARIEITGAIAGDTRKRVLEALKIVEERKFPALLLRIDSPGGTVGDSQEIYSALKRLREKIKIVASFGNISASGGVYIGMGAEYIVANPGTITGSIGVIIRGNNLERLLEKVGVSFQVIKSGPYKDILAFDRELTAPEQQILQELIDTSYQQFVETVAEARKLTVEKVKSFADGRVFTGQQALELGLVDRLGTEEDARRWTAELAGLDPEKTESCTLEKSKPFLNRVLGSSLDISGLSAYKNWLKFEVSTSGLPLWMYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWU1</accession>
    <name>A0A2G4EWU1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmF</name>
        <name evidence="4" type="synonym">rpl32</name>
        <name evidence="6" type="ORF">CP500_018405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006632406.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000132.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54022">
        <property type="protein sequence ID" value="PHX54022"/>
        <property type="gene ID" value="CP500_018405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044958">
        <property type="entry name" value="Ribosomal_L32p_plant/cyanobact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36083">
        <property type="entry name" value="PTHR36083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="57" mass="6353" checksum="FE66A4CD02F501C2" modified="2018-01-31" version="1">MAVPKKKTSKSKKNMRKATWKRKAVVAAQKALSLGKSVLTGRSNSFVYPGNEEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWW6</accession>
    <name>A0A2G4EWW6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_020315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000166">
        <property type="protein sequence ID" value="PHX53657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53657">
        <property type="protein sequence ID" value="PHX53657"/>
        <property type="gene ID" value="CP500_020315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="157"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="448" mass="49562" checksum="6B4DF4EEAD2E3ED3" modified="2018-01-31" version="1">MLKILVIEDDELIRETLVQLLEFQNYRVIVAQNGRVGVQMALSEIPDLILCDVQMPELDGYEVLRTLRQNSLAATIPFIFLTALGAKADFRRGMELGGDDYLTKPFTKAELLGAISSRVSKRQTITQPLTVALQQAEARLNDLVNDSTTSNPVCSEKLALEALLRRALAQGEFQVYYQPQVDIPTGQIIGAEALVRWQNPDRGIISPCEFIPLAEETGLIIQIGEWVLLSACAQAASWLAAGFSPFRISVNLSPRQLSDPQLKTRIVQILETTGLEPTNLELEMTESALVENATVAGTTINELKALGIRIAVDDFGTGYATLGYLKQFAFDSLKIDRIFVRNANEDAQNAAITTAVILLGHSLNMTVIAEGVETEAELAFLKKHQCDIMQGYLFSRPQPTSIFENLLVADQHLFELPTETVPSQVISFVPFSDREKPKNISMSADFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX23</accession>
    <name>A0A2G4EX23_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Biosynthetic arginine decarboxylase</fullName>
            <shortName evidence="11">ADC</shortName>
            <ecNumber evidence="11">4.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">speA</name>
        <name evidence="17" type="ORF">CP500_018120</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11">Catalyzes the biosynthesis of agmatine from arginine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>H(+) + L-arginine = agmatine + CO2</text>
            <dbReference type="Rhea" id="RHEA:17641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="EC" id="4.1.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.19" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54079">
        <property type="protein sequence ID" value="PHX54079"/>
        <property type="gene ID" value="CP500_018120"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00186">
        <property type="reaction ID" value="UER00284"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06830">
        <property type="entry name" value="PLPDE_III_ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01417">
        <property type="entry name" value="SpeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040634">
        <property type="entry name" value="Arg_decarb_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041128">
        <property type="entry name" value="Arg_decarbox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002985">
        <property type="entry name" value="Arg_decrbxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43295">
        <property type="entry name" value="PTHR43295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17810">
        <property type="entry name" value="Arg_decarb_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17944">
        <property type="entry name" value="Arg_decarbox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001336">
        <property type="entry name" value="Arg_decrbxlase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01180">
        <property type="entry name" value="ARGDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01273">
        <property type="entry name" value="speA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0745">Spermidine biosynthesis</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="14">
        <location>
            <begin position="131"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Arg_decarb_HB" evidence="15">
        <location>
            <begin position="405"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Arg_decarbox_C" evidence="16">
        <location>
            <begin position="614"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate-binding" evidence="11">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11 12">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001336-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF17944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX54079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="669" mass="74783" checksum="C22C69EA2F983237" modified="2018-01-31" version="1">MSSPTTTASFPIEPLSTQPPTVKNLATPDTTLSTKAQLPKKSWTIEDSEKLYRIQGWGEPYFSINAAGHITVSPKGDRGGSLDLCELVESLKQRNLALPLLIRFSDILEDRIDRLNSCFARAIARYNYKNVYRGVFPVKCNQHRQLVQDLVRFGQPHHFGLEAGSKPELMIALATLKTPGALLICNGYKDRQYIETAILAQRLGQTSVIVLEQIEEVELAIAASKELGIKPILGVRAKLSTTGVGRWGGSTGDRAKFGLTIPEIVRAVEELKKAGMLDCLQLLHFHIGSQISSISVIKDAIREASHIYVELAKLGANMNYLDVGGGLGVDYDGSKTNFHASKNYNMQNYANDVVAGVKDACDERKVAVPIIISESGRAIASHQSVLIFDVLGTSEVLREVPEPVDENAHQIPRNLYEIYQSITPENYQEVYHDAIQFKEEAISLFNLGYLGIAERAKTEQLYWACCEKIQAIAREKEYVSDDLEDLEKVMASIYYINLSVFQSVPDSWAIDQLFPIMPINRLDEEPTQRGTLADLTCDSDGKIDQFIDLRDVKSVLELHTLKPGEPYYLALFLGGAYQEIMGNLHNLFGNANTVHIQLTPSGYHIEHVVKGDTMKEVLSYVQYDAESLIESIRRQTEEALQQNKITLSESQLLLQNYERSLTQYTYLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXA1</accession>
    <name>A0A2G4EXA1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000124">
        <property type="protein sequence ID" value="PHX54108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54108">
        <property type="protein sequence ID" value="PHX54108"/>
        <property type="gene ID" value="CP500_017870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8882" checksum="D522ECDB1CD3768E" modified="2018-01-31" version="1">MVLILREFYSFVAEVKTKSFSDVGEYKKGKNVRTKKVNARKLMVSVIKDIPMIQNVAMRSGDRNTYSFRSVKPYSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXE4</accession>
    <name>A0A2G4EXE4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hybrid sensor histidine kinase/response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017375</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000115">
        <property type="protein sequence ID" value="PHX54205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54205">
        <property type="protein sequence ID" value="PHX54205"/>
        <property type="gene ID" value="CP500_017375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="10"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="175"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="128"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="401" mass="45702" checksum="4F6CCDAFB61838B9" modified="2018-01-31" version="1">MKDKNSERSIILIVDDNQTNLDVLFELLKNYGFKVLVAQDGESAIEQIEYIHPDLILLDIMMPGIDGFETCRRLKADQATQDIPIIFMSALSDTVDKVKGFQTGAVDYITKPFQHEEVLSRIDTHLTIRSLQKKLEEKNSELAHLNQNLEKLVEQKSKQLIDQEKTAIIGRLTQGMVHNLKSPLQVMQTSVDLIETKATKINDYSFFSYTKYILQAITKVNQIMDTLMVKSSKEQKQDVQPVNINELIQRELQLLEGNMYFKNKIKKKYFYDENIANVPLIYAYISQVFYNLINNAMDAMWENKSRELTIVTRQDESKIYMDIADTGCGIAPEDLSKIFDPFYTSKPAKGQEKKEGEPTGTGLGLYTCIELLKPFNGEIAISSNPGKGSVFTVVLPKQQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXE8</accession>
    <name>A0A2G4EXE8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000151">
        <property type="protein sequence ID" value="PHX53827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53827">
        <property type="protein sequence ID" value="PHX53827"/>
        <property type="gene ID" value="CP500_019400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="652" mass="73251" checksum="A5E9DCA079D57734" modified="2018-01-31" version="1">MSSSNYGPYKSQLLNFISKQSRQVADNCDRTWRQVQSATLNATQILLYPAYLLVQSSRMLARQLRESSQKVDLPELQEFVEGENLKFSQNSSLNLWNEGIGTESAIVEIVHLAENLLLPSQTQTNYDNVSFLINGRNATPDIGLQRETQFTEKTTNTSQKLLLEHQPKTQLAEISINNVATINTKPEVRGIATFLPARSLVLVGDENQILDILTVEQQELLESRITWEVANSGPGRREIAKQELKFNLGLEAAAEKSQLPPVRGFWQLMAWVQTSPLAVKRNQFGESILAVKKAIDANTDHHLIISQQITGVKTDRRAIASGNAIDYNTSELTSNFYPKFDRANNSPSFLNLLDRAAVNLEEFNIPQVSKNTVESIIGQPEKIDTATSEPKLSPNTREIVENYARHIEEMIWSSVDYLLGKETAASENTEKSVAIKYALEQQELENTEKNGEKSDRPWLNLQDLFGEQSPATSSPISTSQIATNVKPKIDEIEKLSERRSTLPSTSPYPQAIHTLLTQIKLSLFTKVSKSKPQKELNLETTQKNSLVPTVKESTPTEAEETELAEPKKPEITGKTSKIPSIATTPGNKSSNESPDEYLETKAESMGYIKHPLEQVLEWLDKIMLRLETIAVQLWEWAKINLQKIINSKDKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXI9</accession>
    <name>A0A2G4EXI9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54160">
        <property type="protein sequence ID" value="PHX54160"/>
        <property type="gene ID" value="CP500_017690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="389"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="444" mass="49617" checksum="49D2B4869B008248" modified="2018-01-31" version="1">MQNLMFRESMLGRYNQILMMRSSVPIGCLLFLWLCAGSIASAQTNPPGLDQFSPNPLEITTPDPLTPNNESLSSTQRDELSAALDGLNLEALAKLQAGDGIGAFELWFRELRLRRYLGPQVEIAALSRVGSVAWSSSKNIELKLITQRLQLIQKEVKSELPVNTELLPALAAAFQQVRAKGPTIEVYQEILDNARQKQDILGEGQTLKAIGLIHINWLSYEKAAAVYEELATLIQENRALFAANSAVPNPTVTVGNGAPPQPVTPPTEVDSLRQLAHVYQQSKQPLKAIAAREKLASVYLNLQNPGAIPPLKIAIASDYETLGQINLAAQYYQEAYNLAVPIQQYAHASEALDKLALLYRSQKQFEPTVRIYQMQLLLEERAYNFYGLMNAYDNLGQVYQEMKTYKKALEAYQKGLEVAKRLGHRQEYFAKKILKVNKQLEKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXN5</accession>
    <name>A0A2G4EXN5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Aminomethyltransferase</fullName>
            <ecNumber evidence="3 7">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">gcvT</name>
        <name evidence="10" type="ORF">CP500_016945</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="3 7"/>
    <dbReference type="EMBL" id="NXIB02000110">
        <property type="protein sequence ID" value="PHX54295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54295">
        <property type="protein sequence ID" value="PHX54295"/>
        <property type="gene ID" value="CP500_016945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00259">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022903">
        <property type="entry name" value="GCS_T_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="8">
        <location>
            <begin position="21"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="9">
        <location>
            <begin position="299"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="383" mass="42017" checksum="1E689C8DF888BFA3" modified="2018-01-31" version="1">MAKSTESNNPENPSQLARTPLYDLSLELKARMVPFSGWEMAVQYSGLSNEHQIVRSQAGMFDISHMGKFGLRGKQLREKFQSLVPSDLSRLQPGQAQYTLLLNAKGCILDDIIFYCQEPDATTSEERAVIIVNAATRIRDKAWIVAHLELSNVSFTDLSPDKILIAIQGPEAVNYLQPLVADNLTPIKAFGHLETNLLGQPSFIARTGYTGEDGFEIMVDAEVGKELWQQLLTAGVVPCGLGARDTLRLEAAMALYGQDIDDNTTPLEAGLGWVVHLDSKGDFIGREVLEQQKASGVSKRLVGLEMAGKHIARHGYPVIFEGEKVGEVTSGTLSPTLNKPIALAYVPTKLAKIGQELEVEIRGKNYPATVVKKPFYRSPNRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXP5</accession>
    <name>A0A2G4EXP5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_016925</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000110">
        <property type="protein sequence ID" value="PHX54291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54291">
        <property type="protein sequence ID" value="PHX54291"/>
        <property type="gene ID" value="CP500_016925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16383">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008629">
        <property type="entry name" value="GUN4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037215">
        <property type="entry name" value="GUN4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05419">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140869">
        <property type="entry name" value="SSF140869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="129"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="555" mass="63271" checksum="B50D13CAD4E600B5" modified="2018-01-31" version="1">MPKSTSRKPSRNRVFATIPNYNPKTPKNPVSHLTQRPPETGFLRQYLTTTQKLPKNPVSEPHPKPQETGFLRQYLTTTQNLGKNPVSQHPTKSLNQNSPISAIIKTIHSIHKPAMRRWPDGQQLDDGKYIIEEYLGGGGFGETYRAQNRHEGKSVAIKTLNLFQQFQPDFAKTQNKFLKEAMSLAKCRHPHIVEVYDIFREGDFNCMVMELIDGIDLATHIKENGRLSEQKALSMIQQLGDALTCVHKQNLTHRDVKPENIMLRKRGMEAVLIDFGLARQATLSGKLMTNSSRGTEHYAPIELAEQRSQLGPYTDVYSLAATLYNMLTDNKPIPSPGRKIIDPFIQPKQYDNKISDRVNAAIIKGMELEPQNRPQSVQEWLDLLIPKPVAAETTRVISAVGMDYINLRNLLAAKKWQEADEETLRVMLKVAGREEEGWLDTESIDKFPCEDLRTIDQLWVKYSNGRFGFSVQKPIYQSLGGTSKYNSEVWAAFGDKVGWRKNEEWLTYKEITFSEKALEAHLPLRLIWGRIFASFCFVGMVDDGVFGRLLSRRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXS8</accession>
    <name>A0A2G4EXS8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54344">
        <property type="protein sequence ID" value="PHX54344"/>
        <property type="gene ID" value="CP500_016670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="526" mass="56703" checksum="4F61432221048137" modified="2018-01-31" version="1">MVSDVSSYDVICFGDEVPGVLAVISAAREYLRRTNRYPRILLMSKGSLQEGIGGHLVRGRLAYLDRSQISPELQKSLGLDTFGSPAAIYKEFLQKSGVMGIALDPEKAHAALKEMLFQANIALLSKVEIKSVSKQGQKIASITTSKGTIYTGKQFIDATVNGELAQAAGVKKLKGFETFGLPYSELPVTLVFETAGLSTRRLKELDYTYLKRFTNIADSENQKFLLHAAGMDAKLAEELRMEMLDTRGNLKTLWAGNDYIDVRSPALPVSYHSFRGTRLLFPQTSAILDEGNIAILPGEKLSWNALLFAVNSTEAETLARSGGKPTARMLQEMSSVVTWLKSLGATSVIPASELYIRHAGNITGVVEPLTGAQMLFGGVPANEALATFSYHFDVRGGIIGIGEKANSQGWFKSLSFKPPTFNIGIRHALVKNVPNLAVVSPCSGFEGLACSVGRIVEFNAAVGQGVGIAAIIAILNNKNLADVSNREVRQVLATTGQLPKIFGVANNSEGTLLAQFEGLFDSSYIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY16</accession>
    <name>A0A2G4EY16_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Branched-chain amino acid ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54422">
        <property type="protein sequence ID" value="PHX54422"/>
        <property type="gene ID" value="CP500_016190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_16" evidence="1">
        <location>
            <begin position="23"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="541"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="886" mass="98778" checksum="ABB5432E078C7A12" modified="2018-01-31" version="1">MTHSPVRRNPYIIGRPINEPELFVGRESIFRFVEDNLRRGEKVILLDGQRRIGKSSVLRNIPKFVASDEFVFVPFDLEDYSQEQLSSILVALAKEIIEHLELDAAKIRLPSIAELETEPYIFSSKFLPQVYEALGEKNIVLLFDEFDILDSEYLVPVFEDFLPYLQSVIELDNKLFTVLFLGRQSPDLPKLLSLFKDAPYQEIGLLDEVSVKRLITKPAQGILEYEPDAIKAILELSAGHPYFTQVICFAIFGRARDVDNWTVTRADVESVVDKAIESAEAGLAWFWDGLSLPEKVVFSAAAEAQKISSEKADKFPENLLNLLKIYGVFRTESLVKAAEQLVEGVFLDNKTRKVKIELVRCWLVKRHPLEQEVDELKKLEKVELKTVNYSISEQLSAQKQELANTVSPSNALAIKQRFLLGTVAAIGLISFAVWLGVYRLVMPCPVGENKELGFFCIADTSINISRGDRTLFPITGNTNRDRGIAAFKKGNYSEAAQFFKNAVVDNRNDPEVLIYYNNALAKQQGSPITLAVVVPVDNREPMAKEILRGVAQAQNQFNQKGGLNGRLLEIVIANDGNKPEQAKQIAAELVKDKSVLGVIGHYSSDATKPALDEYKLAEVAIISPTSTSTSLQGDNFFRTVSSDATAGKKLAEYARKSLNLNSVVIFYNPDSTYSDSLREEFTKNFEKLGGSVVRKIDLTEPKFDPETEVAKSLYEDNAQAVVLFPNTQNTDVALKIVTANAQQTARLKNSPQNPQRQGLKLLGGDTLYSQTTLGGGVQDVEGLILAVPWFREAREAKNFAKKAADQWRISVNWRTATSYDATQAFIQALSPNPTRATVLRGLKNINLPESQTSGYPLKFTSEGERQSEAILVKVVGDKFVLLESQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY27</accession>
    <name>A0A2G4EY27_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Branched-chain amino acid ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54421">
        <property type="protein sequence ID" value="PHX54421"/>
        <property type="gene ID" value="CP500_016185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="AAA_16" evidence="2">
        <location>
            <begin position="22"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="418"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="457"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="3">
        <location>
            <begin position="641"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="984" mass="111203" checksum="1A614EBAD4CA8102" modified="2018-01-31" version="1">MAGQNNRNPYIIGRPIHETEIFFGRESLFRFIDDNLRQNAQVILLHGQRRIGKSSVLQQIPNFFRNNEFVFVDFDLQYQGQSTLSSILHCLANDIIDRLQLEGRVQPPNLEELAADTKIFSDNFLPSIYQAIGESNLVLLLDEFDVLDNQNNDIVNKGARFFDYLKSLTSEQKRFFIIPVVGRHVNDLENLLSLFRGAPYQEIGFLDDLSAQRLIKNPARTILTYEQEALQEIRKLSGGHPYFTQVICSCLFTKANLNNNWTVTHADVESVVDKAIESAEASLPYFWDGLSISERVIFSAVAEAQKIAIEKKQSLPEEPLTLLKNYGVIETNSLVEAAKKLAKNGFLDDTGRRVKVELVRLWLVKRHPLRKEIWQLEQLDIENVTRLCEVANSLKQQGKKDDSLRIYEQVLVLNPNHFNTVLSLAEEYLENQNFDKALELYERSYQFDQANNKECLVNALQKYGHELITQQTFSRAKKQFSRILKIDPDREFAQQRLKEIAVFIRRSNSSIQIQRKQVWIGLIAVATIATVGFGAYRVATPCPPGQQKVLLGIGCEPDTRRISRGDRTLFPNPNIKNTNRDRGIAVFKKGNYSEAAQFFKNAVVDNRNDPEVLIYYNNALAKQQGSPITLAVVVPVDNREPMAKEILRGVAQAQNQFNQKGGLNGRLLEIVIANDGNEPDRAKQIAAELVKDPSVLGVIGHNSSDATKQALDEYKLAEVAIISPTSTSTSLRGDNFFRTVPSDADAGKKLAEYARKTLNLNTVAIFFNPDSSYSDSLREEFTKNFEKLGGSVVRKINLTEPKFNPETEVAKSLWRYKAQAIVLFPDTQKTDVALKIVTVNAQQTAMLKTRPQNPQRQGLKLLGGDALYSQITLDKDVQSEGLILAVSWFREAPEAKNFAIAARQQWGGDVNWRTATSYDATQAFIQALSPNPTRATVLRRLKNINLPDSQTSGYPLKFTSEGELQSESILVKVERGEFRLLQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY68</accession>
    <name>A0A2G4EY68_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Site-specific DNA-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_015925</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245732">
        <property type="entry name" value="M.Tbo703ORF15925P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54472">
        <property type="protein sequence ID" value="PHX54472"/>
        <property type="gene ID" value="CP500_015925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="4">
        <location>
            <begin position="23"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Mrr_cat" evidence="5">
        <location>
            <begin position="355"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="504" mass="57409" checksum="2BDD32002FD8F44A" modified="2018-01-31" version="1">MVNQLFYGDNLDVLCRHIKDESVDLCYIDPPFNSKRNYNQIYNNIGKEDQAQTQAFIDTWTWDDYANQGLAEILENYQGKFTAQSIDLIAGLTKVLSKGSLLAYLVHMTLRVVEIHRVLKPTGSFYLHCDPTASHYLKLILDAIFCTQGGDFQNELIWCYSIGGKSKNKFGKKHDVILFYTKSNRDTHTFNQQSAAIPRKANSHMKVGIDSDGRQYQEKMDKKTKKVYTYYLDEGKIAEDYWTDIETLNREDRERLGYPTQKPEALLERIIKVSSNEGDVVLDAYCGCGTTVAVSQRLNRQWIGIDITYQSISLILKRLEDTFGKGVLEQLKLNGIPKDMEAAVALANKKDDRTRKEFEKWAVLTYTNNRATINAKKGADQGIDGIAYFQGDKDEPEKIIVQVKSGKVQSGDIRDLQGTITLEQAALGIFISLKDPTKEMIKTAKSAGIYQSRYMSQTSDKIQIVTIKEMLEQKKRLDVRLSFEVVKSAEKQMEVKAKQLELDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY91</accession>
    <name>A0A2G4EY91_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000121">
        <property type="protein sequence ID" value="PHX54137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54137">
        <property type="protein sequence ID" value="PHX54137"/>
        <property type="gene ID" value="CP500_017715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="367" mass="42242" checksum="20AFE05ED9E8EB07" modified="2018-01-31" version="1">MQNFRNYYQILGVPKDASADEIKKAYRRLARQLHPDVNPGDKSAEDRFKDINEAYDILSDLDKRAQYDQFSKFWKQKGFQGNSGVRIPNFATWGNGKSSRKRTAENVDFSDYSDFNKFLDQVLGRRREVRMATANDAAARVSSPEPWSTASKKTSYVANSREDRREMDDREIRREDREIPDREIRREDRREMDDREIRRDIEARLTLRLEKAYSGGTERIRLEDGRSIEVNLPPAMVSGQRIRLRNQGIAGGDLYLKITVSSHPFFRLEMSDICCELQLTPSEAVLGGDVEVPTLDGRVKMKLPPGVPSGKRLRLANKGYPTGNGDRGDQLVEIVVVIPKEISDEERELYEKLRQIESLKPRQDLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYA1</accession>
    <name>A0A2G4EYA1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RluA family pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54499">
        <property type="protein sequence ID" value="PHX54499"/>
        <property type="gene ID" value="CP500_015795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="2">
        <location>
            <begin position="397"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="595" mass="67053" checksum="27A2ED99EE3B2AE0" modified="2018-01-31" version="1">MVFLHTLLDFTDANWDSIASSSNYWYQGLCPQSGDLLRLPRTFECEAIARGLMQHLAGDECHSREGKMYGVLLVETVGGVKMVLKAFSGLLNGCSAVEGWVEPIPGRDRVALAEAHTLAELESMKQELIALKELPQRGEYERLLREFELELGDLGDRHKTCKQQRDEKRDLLCRTLVGETLEIALEELNQASRLEGIERRQFKRNRDEKLQPLKHLIDLADQQMREVKQRRKELSRELQTQMHEAYTLVNFLGKSRSLQQLMPSGSIPTGTGDCCAPKLLHCAALHNLKPLAMAEFWWGPSLGDKVQGEFYGACGDRCQPLMGFLLSGLSQNRDGLEAHPTKINFDCGTGILPVANNRNRGGQDAHPTNNDYDCGTGILPVPDPREMLPIIYQDKWLIVINKPSGLLSVPGRYLENQDSVLSRFRNLLADSFNLNAVHRLDLETSGILILARDKKTYRELSLRFEKKQVHKVYEAVLSGVINMKFGSIALPLWGDPENRPYQQVNFESGKPSVTEFQVIGREGNCDRLEFVPLTGRTHQLRVHAADVRGLGIPILGDRLYGCSAVASRLHLHAREISFEHPQLGKRLYLKAETPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYI5</accession>
    <name>A0A2G4EYI5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF541 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54595">
        <property type="protein sequence ID" value="PHX54595"/>
        <property type="gene ID" value="CP500_015260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="26360" checksum="966093AFB3B98B50" modified="2018-01-31" version="1">MNPIVRSRDRLNFRSLLTALCLTLTLVSFTGLDRAEAQEQRLRTLTVTGRGIAAIPTTQTQVRLGVEVQGKTATEVQQEAARRSSAVVELLRSRQVEKLETAGITLNPIYNYESKPSPQITGYTATNTVTFRINTQSAGTLLDDAVNAGATRIDGVSFVAAESAIESARKQALKTATQDAQSQADAVLSALNLKRGEILSIQVNGASAPPPVYRQFAATRGAVADATTPVVGGEQQIEASVTLQISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYJ8</accession>
    <name>A0A2G4EYJ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">F420-0:Gamma-glutamyl ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54599">
        <property type="protein sequence ID" value="PHX54599"/>
        <property type="gene ID" value="CP500_015280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="393" mass="42842" checksum="88CB58BEB28FF0CF" modified="2018-01-31" version="1">MIETLATGIAAAGSLLALGGLGLELNYRLLPRGNKLELTAGEWHLAINEANHYLLVGEMEFRNLTKRFEIMLPEVRAKVKLISDASLDDVTSKTKVIPCHKDASARPDDYWFGYIVKAQASTKIKVSIDIHGQDLTKLQSAWVQVHFTTYGPGGRIPKVRHVVVPLQFPNSETVPNARNVGVAEVLPIRTHILTEIDNPVEIVKRYVLPRAQKGDIVALAETPLALMQGRYRHPSEVKPGWAAKRVCLFFLPMSSLATACGMQTLVDVVGPWRVVAAFAIGAVAKVFGKPGVFYQLAGEQARLIDDVTGTLPPFDQFIVLGPENPQQVVEQIQRETGLAAAIVDANDLKAVKILAATSDLSVTFLEQALRSNPAGNADERTPVVVIRPLSKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYK7</accession>
    <name>A0A2G4EYK7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphonate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54257">
        <property type="protein sequence ID" value="PHX54257"/>
        <property type="gene ID" value="CP500_017145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015416">
        <property type="term" value="F:ABC-type phosphonate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03256">
        <property type="entry name" value="ABC_PhnC_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012693">
        <property type="entry name" value="ABC_transpr_PhnC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="246" mass="26790" checksum="1CF45E813F61201B" modified="2018-01-31" version="1">MTIECCNLETAYSKSLNRPILNGIDCKIKQGEFVALLGLNGAGKSTLLRSFVGLVPVKTGEIRINDIVMNTRTIAKIRREIGLIFQGGGLVKQSQAIENVLCGCLGGLNTWETLWGFPKQKRDRAFELLANFGLQDLAYQKTGLLSGGQQQKVAIARALIQSPQILLADEPTTGLDVIAAQQVMEILAKLHREQGMTVVVVLHDLGMASNYLERAIVLDAGQIVYDGKCHNLSDKFSKLTNPKIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYP0</accession>
    <name>A0A2G4EYP0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA gyrase subunit A</fullName>
            <ecNumber evidence="8">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gyrA</name>
        <name evidence="11" type="ORF">CP500_015060</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54639">
        <property type="protein sequence ID" value="PHX54639"/>
        <property type="gene ID" value="CP500_015060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01897">
        <property type="entry name" value="GyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005743">
        <property type="entry name" value="GyrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="10">
        <location>
            <begin position="11"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="429"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="746"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="904" mass="100436" checksum="1A6994D1B270FBA3" modified="2018-01-31" version="1">MSTSESRIIPTDLGNEMSRSYLEYAMSVIVGRALPDARDGLKPVHRRILYAMNELGLTPDRPFRKCARVVGEVLGKYHPHGDTAVYDALVRMAQDFSMRERLINGHGNFGSVDNDPAAAMRYTECRLTSLTYDAMLRDIDCETVDFGDNFDGSQQEPLVLPARIPQILLNGSSGIAVGMATNIPPHNLGEVIDGFVALIHNPEITDLELMQYIPGPDFPTGGQILGKATIREAYTTGRGSITMRGVASIETIEHVGRPDKEAIIITELPYQTNKAALIEKIAELVNDKRLEGISDLRDESDRNGMRIVIELKRDAYPRVVLNNLYKQTPLQSNFGANMLALVNGEPQLLSLSQFLNVFLDFRIETITRRTQYELRKAEERDHLLQGLLIALENLDGIIQLIRRAPDSAAAKQELIDNYGLSDQQSDAILQMQLRRLTALEAQKIQQEHEELRTKIADLEDILARRERILEIAEVEALEIKTKIATPRRTVIEHAEGEIDERDLIANEQAIILITEQGYIKRMPVSTFEAQSRATRGKAGTKMKEDDGVEHFLSCCDHDTVLFFSNRGVVYSVKAYQIPVSSRTARGMPVLQMLPIPMEEKITSMVSVTEFSTEEYLVMLTRSGYIKKTALSAFGNIRTNGLIAISLEEGDQLRWVRRAKVGDSIIIGTSQGMAIHFRTNHEQLRPTGRATRGVKSMKLRSGDELISMDILPSSIVAEIAELETGELELDGANIALLETGDSELESADIAELETGELELEEEELELEAEEIEGEDAEEITTANSEVPSVLVITTNGYGKRVPVSQFRLQRRAGKGLTATKFKSKKAKDRVAALRIVNDSDELMIITNRGIIIRQAVSAISTQSRTATGVRVQRLDEDDSIVAVALVPPSGEESIEDAESEEVTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYW7</accession>
    <name>A0A2G4EYW7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54704">
        <property type="protein sequence ID" value="PHX54704"/>
        <property type="gene ID" value="CP500_014700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="44"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="163" mass="18425" checksum="BF346A88EAE13E25" modified="2018-01-31" version="1">MLENDRTQPKLPPAGAIQSLSGIDSGGWFEYLVRVYPHHTDYSGAVWHGTYVSWMEEARVESLRSIGIEYADWVSQGWELPVVELSLRYHRAPKMGQSVAVRTRMASEGVRLLWDYEMRSTDGEELYATAQVTLVAVDGEKGKIIRQLPPMLKDAFAKLSIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYW9</accession>
    <name>A0A2G4EYW9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000082">
        <property type="protein sequence ID" value="PHX54714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54714">
        <property type="protein sequence ID" value="PHX54714"/>
        <property type="gene ID" value="CP500_014620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="1">
        <location>
            <begin position="758"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1225" mass="140053" checksum="37709F6ED5227004" modified="2018-01-31" version="1">MIGADFGLLFEVGFNIGILAYIQKEKIAHNFGDSYRLDLQKLELPKMMAEITREANLLGSLDAKIVEKWSLFFVQKGFIGGLNFFREYLTSTGWTLRLSQILYFQCSLSCANSIRTQNDDKTEVFKAFKKVLSQFETAPPNFSDDEINSYIQRYKKTGEFLQADTLMLLQYENDFRILCVDLSAFTPPLTSEKVDNLNEIEVIRKYLLREISYLRSKSVFSNLRMDTSTLGVDFSEDLKGYFTAFKYKDKESVKLIQAGSYAHSFYGFLQQTGILGQDAEVLFNVVGYGDRNISTISLRQDKLQLLATCAEIYKKEVTNKEISDSRTEVLGVIELNAARSFQEGRKFVDSLLGIEKNLTKPVCHPERIDNFVNSIDIISDKLADKLQIERGLHLRNAHAKLIVKALQSDETYIFLTGNPGIGKTTAIANFLKTHIDDGFLFLYVSPRKQVNLDIIEKFKDKNTGLLCNNRLFCINTNSDIIASYSGKRTVKYSSNSRSENFTEKTVHFLKDNPELQVRENYQRQIARKNETVIEAASLKTMGVLNSICNGIYSLINCRTYNNIVATVSIQSLRMKENRQSTLDYLEQIFQDTYNKRDKQVIPAKMQEISSRIKHIFIMIDEITGDDGGVEFLAGIAKMVKKHELHKPQHGFNTKIIVADASIVDPDVIKQHLENTSHEPDKIYFKKLAKNSDVIEPLQVTPFKFNNLAATVINANSYPARSLQITYKVFIEAVKYNENASLKQDNNLVKRVQSEIIQDINQRLAQPGVEQIIVYIQSKQRLAELIEKIQKEREFEQFTDYLEIHANISEEEKAKIQECKDTAKVIFMTASGSRGLSFPKTKHILVDIPRFQIEKNLMEIIQVIYRGRGEDKQGKTLDGEDKELVFYVSDTAVYYADDAALSLQESKLSLLNLLLILKTAVMTRIVGYGNLGRDKFVMIPIGGKSVSAVGDTFSNKMASLIKTLKSESIRGNRLLKEVYTSLEQLLGRGEFVLTNSDNSRHKGDSYLEMRDDFNKKFLDKCNPLDGLLSYDNLEIGHVCGSLLVVPLANKNLLEKYQMRLHGEIKECLEKKLLKKMRQIRDSKLSPENVISAIRGGAIELLQFLNSDVEKTQYFEQLSQQFDRYYAIPLFAFVSGEEMQEYFADSGLEEPEDMRFRDILSAYMRAMYPVDSVMPIGHKYKDFPFIVFRSYSLEQSRAKMFTDKYLMSSNELNVLNLILSRDANRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ16</accession>
    <name>A0A2G4EZ16_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pilus assembly protein PilM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54773">
        <property type="protein sequence ID" value="PHX54773"/>
        <property type="gene ID" value="CP500_014300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005883">
        <property type="entry name" value="PilM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11104">
        <property type="entry name" value="PilM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019169">
        <property type="entry name" value="PilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01175">
        <property type="entry name" value="pilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="1">
        <location>
            <begin position="15"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="364" mass="39870" checksum="F4117E2A3CDC09A1" modified="2018-01-31" version="1">MVNFFKNLISPRKPGIGIEIASDRINVIQLEKKAQALKIATLASIEVPEDMVQEGQIVDPPGMAELIRSVLADNKIKAKHVATAIPGREAVIRLIPVPSELNNEELRQYMNSEAGLYLPFPREDADVDYQKMGLFVDDDGVEKVQVVLVATRKEVTDTYLETFKEAGLIIDVLEVTSFALIRTLKDQLQQFSSQEAAVLTDIEFDSTELAIVVDGIPQFNRTIPIGTYQIQTALNEAMNLPPTRDTSELQSMTLPVTDTIGLSGNPNPGTNAIMKVLGELADELRRSVDFYLNQSEELEVAQLLLAGPGAAIGKLDEFFMQRLSLPASQVDPIQTLGLEVGEDITLEQRAGLGVALGLGLREVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ73</accession>
    <name>A0A2G4EZ73_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54790">
        <property type="protein sequence ID" value="PHX54790"/>
        <property type="gene ID" value="CP500_014070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011949">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044924">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02252">
        <property type="entry name" value="DREG-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="240" mass="26887" checksum="5C5F853C03EC7514" modified="2018-01-31" version="1">MTKVIFLDAAGTLFDVRGSVGEVYQKLARTFGVIVKSEELNAAFFQSFADSSPMAFPGIEAAKIPQLEFEWWLAVSANAFQIAGVFDQFADFPKFFAELYAHFATAEPWFVYPDVFSALNRWQKQGIELAVVSNFDSRLYAVLKALNLDEYFTSVTISTEVGAAKPDYRIFTVALQKHNCLAENVLHIGDSFKADYCGARNAGLKAVWLNRQQENIDLGKLDLTDKKIEEFPSLDLIVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ76</accession>
    <name>A0A2G4EZ76_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54796">
        <property type="protein sequence ID" value="PHX54796"/>
        <property type="gene ID" value="CP500_014100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9086" checksum="414AD3CB646092BD" modified="2018-01-31" version="1">MLSNILEKTRFLNTCITTKETGFLAKSGLLSNILEKTRFLNTCITTKETGFLAKSGLLSNTLEKTRFLTPPKINIFDVNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ83</accession>
    <name>A0A2G4EZ83_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54800">
        <property type="protein sequence ID" value="PHX54800"/>
        <property type="gene ID" value="CP500_014120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8084" checksum="88952958E5DD51B5" modified="2018-01-31" version="1">MTAISKQRTANSQQQTVNSKQRTVNSKQQTANSKQSTANSEQSTANSQQQTANSEQSTANSQQSTVNRQLTTDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZB6</accession>
    <name>A0A2G4EZB6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Branched-chain amino acid ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54828">
        <property type="protein sequence ID" value="PHX54828"/>
        <property type="gene ID" value="CP500_013950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="82"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="457" mass="47791" checksum="6034F93742D6167E" modified="2018-01-31" version="1">MNFSEKSAAKRPTSTKTNPTQHLNTGGLRTLLLAVGIATFCASCQSPQTPTATTPGSSPATSPATSPAASPIAVSSPSDPNTVKIVSMLPMTGSALGQAQTMVNGIKQALAETDSKACDGKIKIEYEILDDATAAAGKWDPSQVTSNANKVAADGSVVGAIGHYNSGAAKLSIPVLNQANVVMVSPANTYPGLTKPGKGEAKEPNVYYPTGTRNFSRVVPADDLQGAVASNWAKSLGVKKVYILDDQELYGKGIADIFETTAKAAGIEILGREGIDIKASDYKALMNKIKALNPEMIYFGGTTQSNAGQIIKDMRNVGMTADAVKFMGPDGIKEQALIDAGGKDAEGVYATFGGLPPKELTGEGAKWYESYKAKYNAEPEAYAAYAYESAKVIIGAINKVCKNDRAAIRDAVLATKDFNGVLGTWSFDANGDTSLTTMSGNVVKAGKWEFVSALKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZF9</accession>
    <name>A0A2G4EZF9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BolA family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54895">
        <property type="protein sequence ID" value="PHX54895"/>
        <property type="gene ID" value="CP500_013750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="SSF82657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="9307" checksum="FA66D0DF77757170" modified="2018-01-31" version="1">MVTPSQVAEMIQTGLPDAKVKVDDLTGGGDHYQARVVSAAFEGKNRVQQHQLVYGALKQAMASEAIHALALQTFTPQEWEAQSQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZX2</accession>
    <name>A0A2G4EZX2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55053">
        <property type="protein sequence ID" value="PHX55053"/>
        <property type="gene ID" value="CP500_012870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="3">
        <location>
            <begin position="50"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="191"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="229" mass="26594" checksum="D923A27FC44FD3C2" modified="2018-01-31" version="1">MTPQLQTQPLPTKQPEKVLYPDSDGQPMSDNTLQFAWIAKLKEGCEALFKDNPTVFVAGDLLWYPVEGDNKTRRAPDAMVVFGRPKGYRGSYQQWLEDNITPQVVFEILSPRNTLSEMALKLQFYSHFGVEEYYLYDPQRNDLTGWQRDETGLTVIESLDGWVSPRLGVRFVFAEPELEVIRPDGKRFLSYVELMEQRDEIEQQRDEIEQQRDRMAAKLKELGIDPTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F032</accession>
    <name>A0A2G4F032_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF29 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000064">
        <property type="protein sequence ID" value="PHX55122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55122">
        <property type="protein sequence ID" value="PHX55122"/>
        <property type="gene ID" value="CP500_012490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002636">
        <property type="entry name" value="DUF29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34235">
        <property type="entry name" value="PTHR34235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01724">
        <property type="entry name" value="DUF29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="16474" checksum="57DC3C28F0A6372E" modified="2018-01-31" version="1">MEELLTLKTLLLKGDIPGSLAIVEELEEMSKKDIINTIRSYAVILLLHLIKQQAENRTTRSWDISIRNSVLEIQEENKRPKSAGFYLPPEELFMVLETAYRQAINKASLEVEEGRYEPKELSQLVNQEAIISQAMTLISQEAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F062</accession>
    <name>A0A2G4F062_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_014000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54837">
        <property type="protein sequence ID" value="PHX54837"/>
        <property type="gene ID" value="CP500_014000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="77"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="169" mass="19130" checksum="76DB22C83DA3D851" modified="2018-01-31" version="1">MMISDISEAQQQRNYRIIVWALIFLTLLGLAFRLYLAWRTNQTLPDTPARLRGDEPGYERFAYDLLNGYFFERPGRTPVYPFFVAGCYAIFGRSPASVVYIQAFLGATTIPLTFILARRFTGPQSSLVAAGLIALHPSLILNGRMAIRPYAPNARNLNAEQLRQLAINW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0E6</accession>
    <name>A0A2G4F0E6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55230">
        <property type="protein sequence ID" value="PHX55230"/>
        <property type="gene ID" value="CP500_011870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12511" checksum="2FE2C7C226AB97C9" modified="2018-01-31" version="1">MARTRSWNYRFSFCKKTSDRPFYALQALGLDGESQPHQRIEDMAACYIKAMQAVQPLGPYILVGHSFGSWVAFEMAKQVQEKGHEIALLAVIDFWEPMTNNSVLTSIEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0F8</accession>
    <name>A0A2G4F0F8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55254">
        <property type="protein sequence ID" value="PHX55254"/>
        <property type="gene ID" value="CP500_011780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="33"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="303" mass="36057" checksum="DD729FC68FC1E29B" modified="2018-01-31" version="1">MYIPDSQSSPAKALPTMYDLPSEDPDEHGFDEYHRWQAQLLCASCIPPNHPADRVFSASDLNLYYDSNHPNWYKRPDWYLVVGVSRFYQDRDLRQSYVIWDEAVNPLIAIEFLSPSTEDEDLGLTESEPNKPPTKWEVYERILKIPYYFVFSKYNNQLRVFRLIGNRYREQILTGSRFWIPEIQLSLGLWQGAFLQNERLWLRWYDINGNLVPTPEEFAKKQALLESQRAEFERQQAEIERQQADIERQQADIERQRAESEKQQAESERQRAEFEKQQTESERERANRLADRLRAMGINPEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0S1</accession>
    <name>A0A2G4F0S1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55352">
        <property type="protein sequence ID" value="PHX55352"/>
        <property type="gene ID" value="CP500_011170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="412" mass="47144" checksum="53E04059AEA4004B" modified="2018-01-31" version="1">MTVTTATNSLNCTPVSAINSLQTAPCEQIIEINHTPSVNILALADFALNKLQAEMKTATRSAQAVAMRIAKEVERICQKSDRIQVSGEVQAWQITLAEHRLQKTLEFYRLGSKQGRVELHSHLASMIYRHVASFRSNLNYQARYNMIEDFLQGFYIESLRAFRREHEVDATYQPRTQLELAEYMAFTEHYAKRQIGLPGRNRQRLIVLRAQGFAKGQPPETAIDIEMAVESGKGEDAEMHSRSPALQQVREQMVSETVDPADAVLRDRVISELIAYLESQNQPECVSYLTLKLQDLSASEIDRVLGLSSRQRDYLQQRFKYHVEKFARTQNWKLVHEWLGADVDQKLGMTSDKWEAFRAQLSPEQQQLLAMKRNQESDKDIATAIKCTPKQVQKRWAQLLDLASQTRNSCQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F121</accession>
    <name>A0A2G4F121_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55157">
        <property type="protein sequence ID" value="PHX55157"/>
        <property type="gene ID" value="CP500_012300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11955" checksum="CFE795541F84B075" modified="2018-01-31" version="1">MSGWELEIFRRNPVSGYCRGGEKPGFFEMSGWELEIFRRNPVSGYCRGGEKPGFFEMSGWELEIFRRNPVSGYCRGGEKPGFFEISRWELEIFRRNPVSGYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1B3</accession>
    <name>A0A2G4F1B3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55542">
        <property type="protein sequence ID" value="PHX55542"/>
        <property type="gene ID" value="CP500_010170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="15935" checksum="3988A2B25766F68A" modified="2018-01-31" version="1">MIRTFDAKSYTDLLVRYQPKPIATGAENDAAIDLASELEHRPARSPEEELFLELLITLIEKFEAENYPMTAGNSASMLQHLMDARNLDKSDLIPFFGTEREVEEIMVNRRAIEIDEARKIADFFQVDISLFLESRSQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1S0</accession>
    <name>A0A2G4F1S0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_009370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.-" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55696">
        <property type="protein sequence ID" value="PHX55696"/>
        <property type="gene ID" value="CP500_009370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="PTHR10543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="477" mass="52429" checksum="EBFECFAB84E7256C" modified="2018-01-31" version="1">MKTDSKTSTKKAWAKPFASPAAEFPLTQLSVKSGQIPPGFRGTLYRNGPARLQRDGVSAGHWFDGDGAILAVHFTDVGAAAVYRYVQTAGYQAEEKADKFLYTNYGMTAPGPIWLRWTKPIKNAANTSVLALPDRLLALWEGGAPHSLDLQTLETIGIDNLGTLSGDFNYSAHCKRDPISGNIYNFGVVPGATTKLNVYKSDSTGKVVQKATVALDGIPLIHDFVLAGKYLIFFVPPVRLKFLPVLAGISSYGDSFEWKPELGTQILVVDAETLSLVSRSKTDPWFQWHFANGFVKEDGDVAVDFVRLADFKTNQRLKEVATGETRTNAEGILCRVHLNPQTGKVTAIEELLDKPCEFPVVPASEIGQASRYVYLAMYRPDVDIVAERYGAIARLDTENHNLTIADCGENRYPTEPIYVSDISSDKGWIVTVVYDGNSDKSEVWIFDSDGLDRAPICQLELPSVIPLGFHGTWKNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F240</accession>
    <name>A0A2G4F240_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55830">
        <property type="protein sequence ID" value="PHX55830"/>
        <property type="gene ID" value="CP500_008740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="366" mass="38785" checksum="10D141DECB2B587F" modified="2018-01-31" version="1">MPNYQHKFWLHQRTIYLSAISLSLILGIAHGLADAAAGFLLGGLPRTMSLEQASWLIILYNILGFGYQPLAGMLTDKFQRPRLAVLVGLFSLLLALAIAQWHSQLAVILAGIGSAAFHVGGGALALTATPDRTTGPGIFAAPGAIGLAVGGAWGWTGYKVSLPIVILLGLMMVIVAIVDLSKYDVFSHDPALSGKETIENSQLDDWVLLVLLSAIALTSTVWTSFQFLLQAHLNVLIAIAFVAGIAKIFGGILGQRWGWRRYTIFSLTIAAVLLLFYPPNYLTLILALALLQSSIPVTLVATAKMMPQQPATATGLALGLAIIMGGIPVMGGLSAIAGIPAVSALIVIVATMSLWWVLKSKIMLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F260</accession>
    <name>A0A2G4F260_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55850">
        <property type="protein sequence ID" value="PHX55850"/>
        <property type="gene ID" value="CP500_008425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="18789" checksum="FC52544FF933C891" modified="2018-01-31" version="1">MKTINIIYRSPNEIDSLIHAFQECTLPRNQWTHEAHLTVALWYLFYDSEQEAINAIRNGIKRYNSAHGIESTKDGGYHETLTLFWVRTIRQYLAQESRNRSIVHLANGLIDKYADRTLPFRYYTRDRLMSSEARNHWVEPDLKSLDSETVRQGLKSLSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F264</accession>
    <name>A0A2G4F264_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55851">
        <property type="protein sequence ID" value="PHX55851"/>
        <property type="gene ID" value="CP500_008435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="167"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="317" mass="35552" checksum="AA1C559C113E33E3" modified="2018-01-31" version="1">MPVPQDIFNESDLEAIAHLINTCEKVDRLNDGTTISELQQEFNAPSLDKARDIRLWFDANGELIGFAQLWISEPAEVIDGSLLFRVHPDARGGDVEAAAIAWGEVRMREVSAIPGAPVKLRSSAHAEDRDRISLLTSSGFKPDRYFCRLARSIWEPIPEPQLPQGFTLIQFPGEQDAEAWVEMFNQSFIDHWNHHDLTVEKFKYDLAKPDYRNDLDLIAVADDGKFVSFCYCEISVDECDRTGRNEGWIACLGTRRGFRKIGLGRAMLLAGLHRLKAAGVETAILGVDADNQSGAMKLYESVGFHNIRNSIAYVKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F267</accession>
    <name>A0A2G4F267_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3120 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55838">
        <property type="protein sequence ID" value="PHX55838"/>
        <property type="gene ID" value="CP500_008790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021468">
        <property type="entry name" value="DUF3120"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11318">
        <property type="entry name" value="DUF3120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="242" mass="26920" checksum="DDCB9896CEBEF4B6" modified="2018-01-31" version="1">MFNFNLLSSAIAPIFTLTNLENPVSSSERSKSIQQWLVFGASAFLVSIPVFVQAPLVRLYPTISLLSTIPWFVLSLILIFRPKTQLWGDLLLGFAGCWLAGSIYWGWFRWEPILHLPIEAIGLPFAIWCLGKSWGKVGAYFYLGSLLGTAITDVYFYLTGLMPYWRQVMHAEPELAMPIFQSAIGQIDTPWGIGCAIVLIAVLLTVGLLSLRDRTLHWRAFSGAVFSTLLVDGLFWLAASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2D1</accession>
    <name>A0A2G4F2D1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55906">
        <property type="protein sequence ID" value="PHX55906"/>
        <property type="gene ID" value="CP500_008400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="22507" checksum="1EDB9D8060A1D0FD" modified="2018-01-31" version="1">MNSNCSRNPVLLIHGIFRKSGVFNKMSDHLTQLGWSVHSINLTPNWGNASLEELAQQLADYIDTNFHPEQPLDLVGLSMGGLVTRYYLQRLGGINRVQRFIAISSPHSGTWMAYTLWGKGCVQMRPGSAFLEDLNRDATVLKKLNFTSIWTPWDFIIVPASSSQISAAKDVKLSVLAHGMMARDSSSLKAVAEALLEPLKVHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2D6</accession>
    <name>A0A2G4F2D6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55908">
        <property type="protein sequence ID" value="PHX55908"/>
        <property type="gene ID" value="CP500_008410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="150" mass="16899" checksum="AC36FEA080988D2E" modified="2018-01-31" version="1">MSARRQIPENIQHQVRQRANCLCEYCHASEQWQYVEFTIEHIIPITKNGTNDIENLALACFHCNRKKSDKTTAIDSQSGVEVALFNPRQDSWNEHFIWSADGLSIVGLTTMGRATVTALVLNRERVINIRAADKAIGRHPPAGDLIQSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2G3</accession>
    <name>A0A2G4F2G3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_007915</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55964">
        <property type="protein sequence ID" value="PHX55964"/>
        <property type="gene ID" value="CP500_007915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="312"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="429" mass="45088" checksum="8220AC2F6A91D3B5" modified="2018-01-31" version="1">MKNDNYNSRSDSNQINVTESKNMPNQTQHHRTLSLPKKLAFLSLILLGSTATVGCNALTSQVPGSSNAIKGETSSPAPISAAPVNILPSQDSNFVTKVVQQVGPAVVRINSSRTVKNQVPDEIPEQFRRFFGSESPIEQPNRVERGSGSGFVFGSDGRILTNAHVVDGADTVTVKLKDGREFVGKVLGVDTVTDVAVVKIEANNLPVVSLGKSEELQPGEWAIAIGNPLGLDNTVTVGIISATGRSSSDVGIPDKRVSFIQTDAAINPGNSGGPLLNQRGQVIGMNTAIIQGAQGLGFAIPIDRAQQIADQLVSTGKADHPYLGVRMLSITPEVKAEFNRNPNTKLRLTEDKGVLVLGVAKNSPAAQAGVSVADVIKKINGQEVSDAGSVQQIVEKSTVGSNMQLEVIRGGKPVTVAVKAGAFPASQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Q6</accession>
    <name>A0A2G4F2Q6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ORF">CP500_007770</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56040">
        <property type="protein sequence ID" value="PHX56040"/>
        <property type="gene ID" value="CP500_007770"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="25"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="208"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="104"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="509" mass="58349" checksum="AE01B340923CD5EB" modified="2018-01-31" version="1">MVTILENPLRVGLRKERVPEPQILVIFGASGDLTQRKLVPAIYQMKRDRRLPPETTVVGVARRPWSHDYFREQMREGIEEFGGGIGNQEFWQDFAQSLFYCPGDIDNPESYQKLKALLEELDQKRRTRGNHIFYLSVSPNFFPEAIRQLGAAKMLADPIKHRLVIEKPFGRDLNSAKALNRVVQEVCQEQQVYRIDHYLGKETVQNLLVFRFANAIFEPLWNRQFVDHVQITVAETVGVEDRAGYYESSGALRDMLQNHLMQIFCLTAMEAPNSLDADSIRTEKMKVLQATRLADLHNLENSAIRGQYSAGWMKGKPVPGYRTEPGVNPQSMTPTFVAMKFTIDNWRWQGVPFYLRTGKRLPKKVSEIAIQFREVPLMIFQSAAQQTTPNVLTMRVHPNEGISLRFEAKMPGPDLRTRTVDMDFSYGSSFGVTSSDAYDRLLIDCMLGDQTLFTRSDEVEEAWRIVTPALMAWEAPSDPALVPQYEAGTWEPAEAELLINRDGRKWRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2T6</accession>
    <name>A0A2G4F2T6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56066">
        <property type="protein sequence ID" value="PHX56066"/>
        <property type="gene ID" value="CP500_007490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="25"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="234" mass="26174" checksum="07452094B138B191" modified="2018-01-31" version="1">MIAPANLSRITIPPLENGDLLSRTEFERRYTAMPKLKKAELIEGIVYMASPLRFEPHAEPHADLMGWLWSYKIATPGVRLGDNPTVRLDVDNEPQPDAVLLIDSRHGGQTRLSDDGYIEGAPELVVEISASTATIDLRDKKRVYRRSQVKEYLVWQVMDHRIDWFSLQEEEYTSLLPDAAGIIRSRVFPGLWLAVSALLNGDMPSAIATLQTGLNSAAHQEFVQQLAAFPNPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2U3</accession>
    <name>A0A2G4F2U3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56070">
        <property type="protein sequence ID" value="PHX56070"/>
        <property type="gene ID" value="CP500_007515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="21905" checksum="C7380B07E74C817B" modified="2018-01-31" version="1">MKNNFESDKNLNDQGSGDALAGCQVHNNYAQGNLTTMTCDRFEMLSAYLDGEVTAAERRQVEDWLVNDPATKALYSRLLSMQQSFQRMPEPASPQSAQELAAKVLQRVERKPKRMIVWGGCAIAALFVAVVSGVGGGRQFAPQFAQSPGNLESEGLVVALNEPMVEIINPNDLILGVDAPVVEIPKSGVAIPHQKTGSEASSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F338</accession>
    <name>A0A2G4F338_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56172">
        <property type="protein sequence ID" value="PHX56172"/>
        <property type="gene ID" value="CP500_006935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="570" mass="65042" checksum="259626E380C2F234" modified="2018-01-31" version="1">MKALSILDEVVFELEQDVNISRIKRIIFFACKEFWENDVRQLASTDLGILIQEMCAKYSKLEDIEAVLNNIVSKVNKKTEYALVADLIICQLSRLYEFEDFTNLETSISRFGGQNAPAFQDEFSSQIPSNEESQRNPGNLFDVRQKILQQTNPLRAKILIFSTLYHEFTFSDRDWLLLKTQELDTLLRQLFNVCPTLVELESQLYRTVNNLENTNENDSSASVIIKAMSPCYANIQQEKRDRAEDAAREDFPSEDCDQTRLINNVDEKANQSESRSNYLETGDITHIIQAAPAHYHDDPQNSYLVPRVAEPSQFQQAEISSNSLTHNFKHELPKTVQYQENSTITEISVPSAATINISESIKQKLGLEEEIKSLVIESANFATTKIENIFSDLESALNRQFSTESPEERLYWKYKVLRDYVGEVQGFTYKLIKILSELESKERGQSTLETQPNFEQNVSSETEPNKSSHKQPNQQQILAMAKQGNPKAIAILINQLLQPKGITAIAGFKDGCLHVIVESAPAPNQQDTATYIYKKLCTLKAKFINNVKIYGRELGNKTILWTQEFVDKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3D4</accession>
    <name>A0A2G4F3D4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YihY/virulence factor BrkB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_006290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56269">
        <property type="protein sequence ID" value="PHX56269"/>
        <property type="gene ID" value="CP500_006290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="138"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="31903" checksum="761E2A53BABD27CF" modified="2018-01-31" version="1">MKLKTVLSLLKQTFTEWQEDKAPTLAAALAYYTVFSLAPLLIIVIAIAGLVFGADAAQGQIVAQLQSLIGKDGAQTVQDLIVKASEPKSGTIATLVGVATLLWGASNVFTNLKEALNTIWNVKPAPGRGIWGFLQDRVLSFAMILGIGFLLLVSLVISALLAAVSYWLNGLLHLPVGIWQIVDFAISFGVVTLLFALIYKLLPDVNLAWNDVWIGAAITSVLFTIGKSLIGIYLGGSGVASTYGAAGSFVIILLWINYSAQILFLGAEFTQVWANRYGSLMLAKRKNLLNQQDLESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3D6</accession>
    <name>A0A2G4F3D6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HlyD family secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56272">
        <property type="protein sequence ID" value="PHX56272"/>
        <property type="gene ID" value="CP500_006305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014315">
        <property type="entry name" value="ABC_heterocyst_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02971">
        <property type="entry name" value="heterocyst_DevB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="75"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="193"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="473" mass="50975" checksum="9520F6F68CFE9764" modified="2018-01-31" version="1">MVHQPTAESLSSSPSLVKQLLVVAALATLAAGGTTGYTTWRSHQPDPNAIAAAAAVTASQLTTVTALGRLEPKGEVIKVSASGSAEGNRIDRLLVKEGDRVKTGQAIAILDNRDRLEAALDQAQEQVRVAQANLAKVKAGAKNGEIQAQKATISRLEADRSNEITAQQAIVARLEVDRSTEITAQQATIARIRAEQLGEIQTQKATIARLQAELRNARSEDQRYSQLYQEGAISASTTDSKKLATETAQQQLNEGKAKLNQIQQSRQQQINEAQAKLNQIQQSRQQQINEAQAKLSQTQESRQQQINEAAANLDRISEIRPVDVQSATAEVNSAQAVAKQAKANLALAYIRAPRDAQVLKIHTYPGEKVGNDGIVELGQTREMLAVAEIYQSDVDKVQIGQPAQITSDSFKGELQGKVEHIGLQVQRQNIVNTDPSANIDARIVEVKVRLDAASSQKVAGLTNLQVKVAIGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3I6</accession>
    <name>A0A2G4F3I6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56330">
        <property type="protein sequence ID" value="PHX56330"/>
        <property type="gene ID" value="CP500_005970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="187" mass="20980" checksum="CA1E7D3B7A904415" modified="2018-01-31" version="1">MVQTLPKSLTLEEFLKLPETKPASEYIDGQIIQKSMPQGEHSVIQGELTSAANAALKPQKVARAFPELRCIFGDRAIVPDVTVFTWERIPRKENGGVANIFAIAPDWTIEILSPDQSQTKVTKNILHCLKHGTQMGWLIDPEEQSVFVYRPTQSTEVFDEPEQLLPMPSFAGEFQLTVGDLFGWLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3T7</accession>
    <name>A0A2G4F3T7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1517 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56422">
        <property type="protein sequence ID" value="PHX56422"/>
        <property type="gene ID" value="CP500_005290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010903">
        <property type="entry name" value="DUF1517"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07466">
        <property type="entry name" value="DUF1517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037221">
        <property type="entry name" value="DUF1517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013713717" evidence="3">
        <location>
            <begin position="36"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="326" mass="34444" checksum="5E987DBE0A5795F9" modified="2018-01-31" version="1">MYKQLISRIKPLLKSLFAIGLVLTLAFSNADGAMAARSGGRMGGGSFRAPARSYSSPSRTYAPSGGGYYGGGGFGGGFGFPFLLPFFGFGGGFGGLFSILIFISIANFLVQSFRNAGGGTDELGNSTPTTVSVARLQVGLLAEGRGLQSELDSLAKTVNTDSATGRAQVLQESTLALLRHPEYWVYAGAESVQTRLEAAEAKFNQFSLAERSKFSEETLSNFNNQIRQSGSNQTLSSAPVNGALVAEDLTQAPGEYIVVTVIVGTQGKLQLPTVRNSEDLRLALRQIGGVSSEQLLAVEVLWTPQANGDTLTADDMLASYPDLRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3V5</accession>
    <name>A0A2G4F3V5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56415">
        <property type="protein sequence ID" value="PHX56415"/>
        <property type="gene ID" value="CP500_005665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="178" mass="19382" checksum="8F440097C8761331" modified="2018-01-31" version="1">MRLSKINLCAIGIFLTLGIFVTAKADRGIAQFSFSNKSTQNLAQTPPSLPSASPAPFPSPVMEKEGPPLTTESGPDQIALAAHLQTIKAKMYGAYWCPHCHTQQELFGKQAFTAVTYIECDPRGKDAQPDLCKAANIKAYPSWEIRGKYYTGTQSLAKLAILSGYKGSRNFQQQVPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Y8</accession>
    <name>A0A2G4F3Y8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56197">
        <property type="protein sequence ID" value="PHX56197"/>
        <property type="gene ID" value="CP500_006725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14769" checksum="C100120FE710B144" modified="2018-01-31" version="1">MSLQQLKEKACQLSVSDRLALLSAIVQSLQTTPEIENWQYLIARPHPWRKQLYIKGHKLLASTIWRDMTANHMSSEQASENWDLPLDAIYEVIDYCENNQELLKLEAEEERYRLEVKGVQLEPTNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F411</accession>
    <name>A0A2G4F411_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56475">
        <property type="protein sequence ID" value="PHX56475"/>
        <property type="gene ID" value="CP500_005130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8023" checksum="D800DEE5A2AABA32" modified="2018-01-31" version="1">MGLIRLRVRELAEEKGWTLKEVSERSGIPYSTVRSYAHSPKLATVDYTALQKLAEVFDVMVEDLVEVLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F471</accession>
    <name>A0A2G4F471_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56560">
        <property type="protein sequence ID" value="PHX56560"/>
        <property type="gene ID" value="CP500_004745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="208" mass="23656" checksum="473BD58DB5BCAB30" modified="2018-01-31" version="1">MIQALTKLVTFDEFIAWYPENSERRYELHDGVIVEMPKGTGQHSEVSGFLNIEVGILCRAANLPYFLPKECVLKPDRDESGYEPDVIVLDRQQVINEPYWAAESIITMGSSVCLAVEVVSTNWQTDYLTKLRDYEEMGILEYWIVDYLGLGGRRYIGNPKQPTVSVYQLVDGEYELAQFRGDNKIESAAFPELNLTAQQVFEAGIVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F493</accession>
    <name>A0A2G4F493_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56580">
        <property type="protein sequence ID" value="PHX56580"/>
        <property type="gene ID" value="CP500_004870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="43"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="11664" checksum="B67D1FA1C0AE055D" modified="2018-01-31" version="1">MDAIKRQRLEAAGWRVGDAADFLELSAEEIAFIEMKLSLIKRLKQLRISQNLSQESLAKKIKSSQSRVAKIEAGDPSVSLDLMVRTMLAMGATREDVALAITSSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F495</accession>
    <name>A0A2G4F495_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Succinate dehydrogenase flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_004880</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56582">
        <property type="protein sequence ID" value="PHX56582"/>
        <property type="gene ID" value="CP500_004880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014006">
        <property type="entry name" value="Succ_Dhase_FrdA_Gneg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01812">
        <property type="entry name" value="sdhA_frdA_Gneg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="9">
        <location>
            <begin position="5"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="10">
        <location>
            <begin position="450"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="575" mass="63677" checksum="921BE32829FA37FF" modified="2018-01-31" version="1">MLEHDVIIVGGGLAGCRAAVEIARTDPSLKVAIVAKTHPIRSHSVAAQGGMASSLQNVDPEDSWKAHAFDTVKGSDYLADQDAVEILTREAPGVVIDLEHMGVLFSRLPDGRIAQRAFGGHSHNRTCYAADKTGHAILHELVNNLRRYGVHIYQEWYVTRLILEEGQAKGVVMYRLLDGQIEVVRAKAVMFATGGYGRVYNTTSNDYASTGDGLAMTAMAGLPLEDMEFVQFHPTGLYPVGVLISEAVRGEGAYLINSEGDRFMANYAPSRMELAPRDITSRAISLEIRAGRGINVDGSAGGPFIYMDLRHMGREKIMSKIPFAWEEAHRLLGIDAVNQPMPVRPTVHYSMGGIPTNVSGQVRSSVDGLVEGFFAAGEAACVSVHGANRLGSNSLLECVVYGKVTGATIAQFVQNRKLPAVDEQHYINEASQQIQALVERPGKYRINQIRQQYQDTMTEYCGVFRSAELMQEGLQKLEELERQYQEVYLDDKGKLWNTEIVEALELRSLIIVGRMILTSALNRHESRGAHWREDFPQRDDGNFLKHTLAYYSPAGINLAYMPVAITMFEPQERKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4C8</accession>
    <name>A0A2G4F4C8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_004460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56595">
        <property type="protein sequence ID" value="PHX56595"/>
        <property type="gene ID" value="CP500_004460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="229"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="773" mass="84560" checksum="64665B648E5F4CE7" modified="2018-01-31" version="1">MQNSVPKNYLWALGEGIKTCRPGDVIAGRYLVKRDRLLIDTQPEQLPELPEDIPNFINPYLRLFAHQLHVPQVYGVVSAKASQLSGDIWLLENGPIKKVTETLMPKLVEEWKGASAMRQLNWLWQIAQLWQPCITQGVASTLLTPELLRVEGPVVRLLELEPDRKPPNLSELGKLWQQWLDDAHPAIVNFLGQLCQQMVARQVRNGEQLIGQLDTALVKCGRWYDRTVEIATGTDVGRSRTHNEDACYPPSGTVLEGIPPGAEACAIVCDGIGGQDGGEVASELAISVLRKKLQQVVLHKDIYEPLSLISKLERAACAANDAIANRNDSEHRQGRQRMGTTLVMALAHLHELYVAHVGDSRAYLITRTGCYQVTLDDDVACREVRLGYALYRDALEQVAAGALIQALGITSSSILHPTVQRFPVDEDCVLLLCSDGLSDKDRVEECWETEILPILDGSIGLAAARDRLIDIANTRNGHDNVTIGLIHCQAYLREESNSFTELSIAALEPIEPIADSEDVPTDLNDRNTVDDGNSEPKTEILQLPDQSKNPFSLFLKILFLLGLGGVFAYFFIPPVGRAIDTAGESIFGKRGVIDTQSSPQTTQETLPSPIQSLERGSFLAIKSSAVGESGQDANPFYLLKKIGEDVKVTVPAGSVLQVINKQVEPEGNWLELKVCSIPEIVESPSPKPKPHKDFSGVFQPKTNQSPAVSTTTSSTSPAPVAKTTVPLEIAKLQAGETGWIQEKDAVFKVVSNPVVKPNQPGKCLVSDSNPNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Q8</accession>
    <name>A0A2G4F4Q8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminopeptidase P family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_003780</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56740">
        <property type="protein sequence ID" value="PHX56740"/>
        <property type="gene ID" value="CP500_003780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="3">
        <location>
            <begin position="20"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="2">
        <location>
            <begin position="354"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24_C" evidence="4">
        <location>
            <begin position="576"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="636" mass="70746" checksum="3DF6F45EA6486F68" modified="2018-01-31" version="1">MVAANLKTNINTQESTHSKLADLRDSMLNYDLDCYFIPSVDEHLNLYGSEAKQRRAWISGFTGSAGDLLVGKNLAWLFVDSRYYEQAELQVDSALIQISKLGLEENLTLIETLEKLAVESAQNQTKLRFGFDPFTLSVEQYQSWVKKFATAGIELIPISENLADKVRWRSPRRGSHNLAKTSETLAAIDESPIFSLPVSLTGESAAEKLARVREAMQKANIDVLPITNLNQIAWLFNLRGSDIPNIPIFISYAIVTTDAAFLFTNPQRVLAEIQQDLHNCATLLPYAKYPETLQDCVSQPKQIRVLLDPKHTTAGTHQLIIDRQSATESNIEIVFEANPIEGMKARKNPVEIEQMKSANFKASKAKTFTLKWLTEQLENGKVLTEFDVKETVERFYQEEADFQSLSFRTIAGAGVNSSIVHYGTPSPEITLKPGEFLLLDSGSQYLGGTTDDTRTVIIGEPTALQIEHYTTVLIAHISCAMQQFPKGAMGVQLDAIARSILWQEQLDYGHGTGHGVGAFLAVHEGPNGISKSVQYALEPGMVTSIEPGYYQPGWGGIRIENLYVVVEMPSKYDTVWYGFEPLTYIPFDRKLINADRLSKTQLAWLNNYHGAVVEKLASAIDPATLEWLKTACVALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4S2</accession>
    <name>A0A2G4F4S2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)H-quinone oxidoreductase subunit 4L</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NAD(P)H dehydrogenase subunit 4L</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NADH-plastoquinone oxidoreductase subunit 4L</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1, subunit 4L</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ndhE</name>
        <name evidence="6" type="ORF">CP500_003430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cellular thylakoid membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the complex I subunit 4L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56793">
        <property type="protein sequence ID" value="PHX56793"/>
        <property type="gene ID" value="CP500_003430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01456">
        <property type="entry name" value="NDH1_NuoK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001133">
        <property type="entry name" value="NADH_UbQ_OxRdtase_chain4L/K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039428">
        <property type="entry name" value="NUOK/Mnh_C1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11434">
        <property type="entry name" value="PTHR11434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00420">
        <property type="entry name" value="Oxidored_q2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="11488" checksum="536984A959710BC8" modified="2018-01-31" version="1">MQLQLQYFLLLAAALFCIGIYGLITSRNAVRVLMSIELMLNAVNLNLMGFSNYLDPVQIKGQVFTVFVVTVAAAEAAVGLAIVLAIYRNRDTVDMEEFNLLKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4V2</accession>
    <name>A0A2G4F4V2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-vinyl reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56769">
        <property type="protein sequence ID" value="PHX56769"/>
        <property type="gene ID" value="CP500_003945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004096">
        <property type="entry name" value="V4R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02830">
        <property type="entry name" value="V4R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00989">
        <property type="entry name" value="V4R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="SSF111126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="V4R" evidence="1">
        <location>
            <begin position="140"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="233" mass="26784" checksum="380E868C9CAA703F" modified="2018-01-31" version="1">MVSTAPTEISIHSESRLKKKYPKTHGHYRFQDFFTFDRPIGTINDWNESRNIFTSEDFIIGLVEGLEEEVGPASSVIMYTIGCQWGLQDAEFFQKWFSAEFGQNIRQSNLMFLLETWWWPFTAQGWGRWEVDMSDRKHGCIFINLYDSAVARTLGDVGKPVCHLYAGLFAGFFGSLVKKPLSCIELQCYSMGETYCKFLLGNPDKIDAAAFWLNEGANARDIQNRIQNGERLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4V6</accession>
    <name>A0A2G4F4V6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Addiction module antidote protein, HigA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">higA</name>
        <name evidence="2" type="ORF">CP500_003860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56755">
        <property type="protein sequence ID" value="PHX56755"/>
        <property type="gene ID" value="CP500_003860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013430">
        <property type="entry name" value="Toxin_antidote_HigA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36924">
        <property type="entry name" value="PTHR36924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02607">
        <property type="entry name" value="antidote_HigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="31"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="11674" checksum="AABA98E08B928EC3" modified="2018-01-31" version="1">MKDIKDIIQGRKVRPVHPGEVISDVLEDIEMTQTRFAEILGVSRRSVNEIVLGQRPITVDMAIRIGKALGNGPQLWLNLQQKVDIWDAVQKHSEEYERVSTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4X9</accession>
    <name>A0A2G4F4X9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dnaK</name>
        <name evidence="11" type="ORF">CP500_003340</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="7">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56844">
        <property type="protein sequence ID" value="PHX56844"/>
        <property type="gene ID" value="CP500_003340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="604"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="645"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="654"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="7">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="704" mass="76314" checksum="7280F812C4FA6B9C" modified="2018-01-31" version="1">MGKVIGIDLGTTNSCVAVLEGGKPVVIANSEGGRTTPSIVGFGKGGDRLVGQLAKRQAVTNAINTVYSIKRFIGRRWDDTEEERARTPYTCIKGKDDTVNVQIRNKVHTPQEISAMVLQKLKQDAEAYLGQTVTQAVITVPAYFTDAQRQATKDAGTIAGLEVLRIVNEPTAAALSYGLDKQHIEQKILVFDLGGGTFDVSILQLGDGIFEVNATAGNNHLGGDDFDDCIVQWLVETFRTQKGTDLSKDKMALQRLREAAEKAKIELSSTESTSINLPFISSDEKGPKHLEKPLSRAQFEKLVAHLVQATIDPVTQALKDANLTPKNIDRIILVGGSTRIPAVQQAISKYFGGVFPDKSVNPDEAVAIGAAIQAGVLGGEVKDLLLLDVTPLSLGLETLGGVFTKVIERNTTIPTSRSQMYSTAVDGQTSVEIHALQGERALVKDNKSLGKFLLKGIPPAPRSVPQIEVTFEIDANGILKVSAQDKGTSKEQSIQISNTGGLSETEVERMRQDAELYADEDLDRTQLVELKNQADTLVYNCGVTLKTNAQLLGDDLKTEAKAASVTLRAAIANPEITCEELEAQIESFKQLLYSLGAAVYEQARSGEATSSTAVESEIVPELDEVEADDDSILPTEELVTIAEPMLELTLELPPEPKPEPKPESKPEPKPEPKPEPKRQKQQNLQTKQKPKVPEPEVDDMNPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F503</accession>
    <name>A0A2G4F503_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-sulfur cluster assembly accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family. Ycf83 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56791">
        <property type="protein sequence ID" value="PHX56791"/>
        <property type="gene ID" value="CP500_003415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031108">
        <property type="entry name" value="ISCA_plant_cyanobact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47265">
        <property type="entry name" value="PTHR47265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="2">
        <location>
            <begin position="11"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="117" mass="12733" checksum="9EC432FEAFEA1FD7" modified="2018-01-31" version="1">MTQAISQKRGIQMTDSAVRQVLGLREKQGKDLCLRVGVRQGGCSGMSYVMDFADPSTVKSDDEVFDYEGFQVVCDRKSILYLYGLVLDFSDAMIGGGFQFTNPNATQTCGCGSSFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5F5</accession>
    <name>A0A2G4F5F5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FkbM family methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56968">
        <property type="protein sequence ID" value="PHX56968"/>
        <property type="gene ID" value="CP500_002460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="250" mass="29015" checksum="3F78D3F829C98F3F" modified="2018-01-31" version="1">MKKQTIKKLLQKNNPVVLEIGASTGEDTLAFLREFTNIKLYCFEPDPRCLEIHKSKVNDSRCQLNTIAISDVDGEAEFYQSSGSYEGFTEYSEWLQSSSLKTPKNHLEAYPWCKFENKVIVPTRRLDAWFEENPLDEIDLIWADVQGAEENLIKGGLKTLSHTKYFYTEYEDDELYEGQITLDQIKNLLPNFKAIGYFGNNVLFKNTALPDSSFNNADQTVWQTWELFPPKVWLQLMKRKLKSKTKSLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5J7</accession>
    <name>A0A2G4F5J7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57026">
        <property type="protein sequence ID" value="PHX57026"/>
        <property type="gene ID" value="CP500_002225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="83" mass="9196" checksum="716BD92F9D3F2204" modified="2018-01-31" version="1">MIEDIYSASPTKPILNRQDACSTIMIEDIYSASPTKPILNRQDACSTIMIEDIYSASPTKPILNRQDACSTIIIKDVYPVSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5K1</accession>
    <name>A0A2G4F5K1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57019">
        <property type="protein sequence ID" value="PHX57019"/>
        <property type="gene ID" value="CP500_002190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="26363" checksum="6A205BCD8A120ADE" modified="2018-01-31" version="1">MANKEHLALLKRGAVTWIEWRNLHPNIEPDLSEANLAEANLRGANLGRSNLFKIDLFKAKLIAANLAEANMSLANLACAQLLETNLVKANLTGTNLQEADFRGADLSFANLIGADMSGANLQQTDSADASLIGTVMCRVNAIGANLNNANLSQANLSQAQLIEAHFYAANFYKANLTEAHLTGAYLFRANLSFADLKSADLRWANLGKVDLRGANLTGANLRGANLAGANLSEANLKETTMPDGSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5P5</accession>
    <name>A0A2G4F5P5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">S41 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_001615</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57123">
        <property type="protein sequence ID" value="PHX57123"/>
        <property type="gene ID" value="CP500_001615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013545376" evidence="5">
        <location>
            <begin position="24"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="106"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="418"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="444" mass="48585" checksum="454820FDBFF4BAFB" modified="2018-01-31" version="1">MVITKRGLVLSAAAMLLTAVTLANTGCSSKSLASFRGSPKELVDEVWQIIDKSYVDGTFNQVDWKAVRKDYLNRTYSTDEEAYKAVREMLKKLDDPYTRFMNPEEFKNMQVDTSGELTGVGIQLTQDEKTKKLVVISPIEDSPAFNAGIQAKDIISKIDGKSTEGMDTNQAVNLIRGKVDTQVTLTILRKNKEIEFKLKRAKIEIHPVRHSVQKSPIGEIGYIRLNQFSANAASEMRSSMQDLEKKKVTGYILDLRSNPGGLLYGSIEIARMWLKEGTIVSTVDRVGETDRQTANKKAITDKPLVILVDGGSASASEILSGALQDNKRGVLVGTKTFGKGLVQSVRGVGNGSGLAVTIAKYFTPSGRDINHLGIEPDVKVELTDAKKEELRRDRDKIGTTADPQYAKALEVLTKKVTGKTGDLKAQSKPNATPAKVKAAQPKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5W7</accession>
    <name>A0A2G4F5W7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thymidylate synthase (FAD), intein-containing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57162">
        <property type="protein sequence ID" value="PHX57162"/>
        <property type="gene ID" value="CP500_001845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050797">
        <property type="term" value="F:thymidylate synthase (FAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.170">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003586">
        <property type="entry name" value="Hint_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003669">
        <property type="entry name" value="Thymidylate_synthase_ThyX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036098">
        <property type="entry name" value="Thymidylate_synthase_ThyX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34934">
        <property type="entry name" value="PTHR34934"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02511">
        <property type="entry name" value="Thy1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00305">
        <property type="entry name" value="HintC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69796">
        <property type="entry name" value="SSF69796"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01445">
        <property type="entry name" value="intein_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51331">
        <property type="entry name" value="THYX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INTEIN_C_TER" evidence="1">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="515" mass="59336" checksum="A8AD1666A55AB57B" modified="2018-01-31" version="1">MDRFRVEVISQTPNPQQVIYAALHQDYTENFVFDDRDSWPSDAECGEIIVKRLLAGDRGHYGPLEHPQIIFNCGYFPHSVMQQARTHRVGVSFDVQCLAADTTITFVDCEGSAGKKNLSKTIGELYDLWTNGEKAIRSRSIQGRNGEPPGEYRRDCKQRIRKMRLRVLNEQTGLFEVGHIKDVMCSGIQPVYKVTLEDGKTLECTTNHRLFTANGWQTMKDAVGLTTASDGNVVSIAKNSYVMCNGLSVTDRLYTEKSWLEAQITKGLTIKEIAGLSDQSLAYDFDNLVTLCKECHEYIHQNNLELEFAKAYSPILEPQNWQVKPKPKGRKLRSHPVKVNSVEYVGEQMTYDLEVDGEWHNFVANGLVVHNSLRYTGNQFLDAAIGKKDIEDIFYLRPVDYYTDREGKKYYYSPEQRQKDLEWCLEAAKRYKIDFDGGMSEEHARGKLPFDYRQHFVVSFNLRSFLHFADLRNKKNAQLEIQKLCEMMWPHFENWAPDIAKWYTTTRLGKARLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F657</accession>
    <name>A0A2G4F657_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57273">
        <property type="protein sequence ID" value="PHX57273"/>
        <property type="gene ID" value="CP500_001135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8882" checksum="3C539840101F87C4" modified="2018-01-31" version="1">MGKQAEALIEKFGDDYTYDQLRQIKKDFGLSKIQYEYPGPVKRNTFTQLEELAKDGDADAKKAIKLLLQTKRLNEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F664</accession>
    <name>A0A2G4F664_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57250">
        <property type="protein sequence ID" value="PHX57250"/>
        <property type="gene ID" value="CP500_001000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="201"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="395" mass="43400" checksum="CC0EDFC803A35D8E" modified="2018-01-31" version="1">MRIIQIIPSISLVYGGPSQMVLGLSAALAAKNIDVTIITTNSNGDIGQLPLDVPLNQPIQQNGYQIIYFRCSPWRRYKFSLSLLHWLNQNAGQFDLAHIHALFSPVTTLAATIARGHNLPYIIRPCGMLDPADLQKKKLLKQIYGTVLEGPNLAGAAAIHFTSKEEAKISERFGLDCTSKMSVPQDLVIPLGVTAGFFPQRLRKSQVPIILFMSRIEPKKGLDLLVPALESILEAGIEFQFILAGSNPQDADYETGIKLKIQNSILAKYTTITGFVGGDLKNELLTNADLFVLPSYYENFGIAVAEAMAAGVPVAISDRIHIAEDIQQAEAGWVGPLEVDAIASLIKSALLNPEERQRRGLNGQEYAKKHYNWEAIAQQTIDSYQEILSSIRHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F670</accession>
    <name>A0A2G4F670_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4359 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57248">
        <property type="protein sequence ID" value="PHX57248"/>
        <property type="gene ID" value="CP500_000990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025578">
        <property type="entry name" value="DUF4359"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14271">
        <property type="entry name" value="DUF4359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="141" mass="15127" checksum="8379BC11A0F37E7A" modified="2018-01-31" version="1">MIIDKAMNTNNSTSKFFGNVGKVAIALTLLAAGMAFTNPGRDKYLTYASGKLQTELENTVCKDSRVPKALSGITDTLIGSCKNLLTSQRSTIEQLLDNTTQRQNLGVVSIYTTEVGKKSYQTVGAFGNFVTLPPAAKDAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F686</accession>
    <name>A0A2G4F686_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57270">
        <property type="protein sequence ID" value="PHX57270"/>
        <property type="gene ID" value="CP500_001120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="17"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="21768" checksum="B6941C5631B01C39" modified="2018-01-31" version="1">MTTLTLNLNPIIKLTDDQFFQLCQENENIRLERTAKGELIIMSPAGGETSNRNAGLTAQIWNWNQRNKLGKVFDSSTGFKLPNSANRAPDASWVKLERWNALTPEQQKKFPPICPDFVVELMSPSDSLKETQDKMKEYRDNGARLGWLINRKSRQVEIYRPNQEVEVLESPTTVSGEDVLPGFVLSLESIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6A1</accession>
    <name>A0A2G4F6A1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine triad nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57221">
        <property type="protein sequence ID" value="PHX57221"/>
        <property type="gene ID" value="CP500_001365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="7"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="99"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="12740" checksum="92311C75F70C104D" modified="2018-01-31" version="1">MTNQETIFSKIISREIPADIVYEDDLALAFRDVNPQAPVHILVIPKQPIAKLADAEYGDRDLMGHLLLTVKLIAEQLGLSNGYRVVINNGNDGGQTVDHLHLHILGGRHMKWPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6D7</accession>
    <name>A0A2G4F6D7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57309">
        <property type="protein sequence ID" value="PHX57309"/>
        <property type="gene ID" value="CP500_000565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="80" mass="9319" checksum="64F2C68814CFF6E5" modified="2018-01-31" version="1">MLTLEMAIQKIQHFPPNQLEKIFEYIEFLEFQANKKTFEPIDTKSQKISFTQAAQEFVGCLDSDLEDLSHNSQYLKGFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6F0</accession>
    <name>A0A2G4F6F0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57271">
        <property type="protein sequence ID" value="PHX57271"/>
        <property type="gene ID" value="CP500_001125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="160"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="52435" checksum="C332696BC2EF63EE" modified="2018-01-31" version="1">MELKEVLRFADDKVFSKTGKHLDDLQEAILKETLQGRKYAAKVAQDRDCSDGYVRVAASELWKILSDVFGEDVSKVNVRAILERAKFYTNFSPTIGSENVTVNNNLNICQERARSPTESPNPQPTPKQLHIDLGDAPQIFTFFDRTSELSTLENWITHDRTRLIALLGISGIGKTTLSLRLINQIKTQFDYVIYRSLRFSPTLDATLTNLLQIFSQPSEIPQNIETKISQLLDYLRKYRCLIVLDDVQMLFSSRQLAGQYQTGYEDYQLFFKLIADVCHQSCLILNSWEKPREIARLSKEDHPVRCFELGSLGEAAKEILNSQKLTDEETWSTLIDIYQGNPLWLELTATLIRELFGGRVAEFLQCEMPILDEGLQFQLSQPFGRLTAAELAVMVHLANLPEPVAVSRFFNKIPFSPSEIVNAVRYLGSRFLLDTIEQEKITLFSLNPVLKQYVKTQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6K1</accession>
    <name>A0A2G4F6K1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_000770</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57345">
        <property type="protein sequence ID" value="PHX57345"/>
        <property type="gene ID" value="CP500_000770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="241" mass="27298" checksum="F44ABB650DAEA582" modified="2018-01-31" version="1">MRILLVEDDLRLAETLAEALTDQRYVVDIVTDGESGWHQANMLNYDLLLLDLMLPELDGISLCHRLRSHGYTMPVLMITARDTLSDEINGLDAGADDYVVKPVDLQKLFARIRALLRRGSSTSPPILEWEEIRLNPSTYEVSYGHTPLHLTPKEYAILELLLRNGRRVLSRSVMIEHVWSLESPPEENTVKVHIRSLRQKLKAAGVTEDLIETVHSMGYRLKQSDSPTNLIGNSLEFKTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Q9</accession>
    <name>A0A2G4F6Q9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3539 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57429">
        <property type="protein sequence ID" value="PHX57429"/>
        <property type="gene ID" value="CP500_000390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021926">
        <property type="entry name" value="PipX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12058">
        <property type="entry name" value="DUF3539"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10542" checksum="196B2B8D40A127AB" modified="2018-01-31" version="1">MTTETYLNHPNFGLLFKVSQVEDSQELFTTLYAQRLFFLVTNGPGGLRFEPISRSDARLMVEIRLRTLRRSALYKEYDQLQVIHKRTFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUA2</accession>
    <name>A0A2G4EUA2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_023150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000270">
        <property type="protein sequence ID" value="PHX53132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53132">
        <property type="protein sequence ID" value="PHX53132"/>
        <property type="gene ID" value="CP500_023150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="20"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="59"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="326" mass="36424" checksum="50A4C6D1122B4986" modified="2018-01-31" version="1">MEPLIDAPTFTEMPATAPVVETFNLGKFYRTGFWMNQKIESLKSCTLTVSEGETFGLLGQNGAGKTTLLKTLLGIVRPTSGRGLLLGRPLGDRTVKQRIGYLPENPYFYDYLTGWEFLQFAAGLFQIPAAVQRQRIPQLLDLVGLAQSAAIKKQLRQYSKGMLQRIGMAQALINNPDVVFLDEPMSGLDPMGRYQMREIILSLKSQGKTIFFNSHILSDVEKICDRVAILARGELICIGAIDQLLGKTEIYRVEGRGGHLNILQKWIPDMDVDRDLWYGHLQGDPKEFIDSLSATGGQLIGMNLARPSLEEFFMQQLEERGIYSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUK1</accession>
    <name>A0A2G4EUK1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxygen-dependent coproporphyrinogen-III oxidase</fullName>
            <shortName evidence="4">CPO</shortName>
            <shortName evidence="4">Coprogen oxidase</shortName>
            <shortName evidence="4">Coproporphyrinogenase</shortName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hemF</name>
        <name evidence="5" type="ORF">CP500_022695</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>coproporphyrinogen III + 2 H(+) + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX</text>
            <dbReference type="Rhea" id="RHEA:18257"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="1.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000241">
        <property type="protein sequence ID" value="PHX53211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53211">
        <property type="protein sequence ID" value="PHX53211"/>
        <property type="gene ID" value="CP500_022695"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00333">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018375">
        <property type="entry name" value="Coprogen_oxidase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="PTHR10755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="SSF102886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01021">
        <property type="entry name" value="COPROGEN_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for dimerization" evidence="4">
        <location>
            <begin position="278"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for dimerization" evidence="4">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="339" mass="38989" checksum="C73E91047E028653" modified="2018-01-31" version="1">MTVSTTLKTATSPFLPPTDSRAKVSQFMKGLQDEICQGLEQLDGSGKFKEDSWERSEGGGGRSRVIREGDVFEQGGVNFSEVWGESLPALILTKHPEAAGHDFYATGTSMVLHPRNPYLPTVHLNYRYFEAGPIWWFGGGVDLTPYYPFAEDAAHFHKTIKAACDKHHPEYYPAFKLWCDEYFYLPHRQETRGVGGIFFDYQNGRCPLYRDHNVKGKAAEYSNQIGKPEDRSWESVFAFVQECGKAFLPAYVPIIEKRRSTEYGDRERNFQLYRRGRYVEFNLVYDRGTTFGLQTNGRTESILMSLPPLVRWEYCFEPEPNSPEAELYSKFLKPQDWAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUQ5</accession>
    <name>A0A2G4EUQ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000246">
        <property type="protein sequence ID" value="PHX53196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53196">
        <property type="protein sequence ID" value="PHX53196"/>
        <property type="gene ID" value="CP500_022800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="51"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="155"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="189"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_41" evidence="2">
        <location>
            <begin position="347"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_41" evidence="2">
        <location>
            <begin position="519"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="721" mass="81320" checksum="67BCA4CCD74891B0" modified="2018-01-31" version="1">MNPDFHNQSETSKSENAASLTVVAEKYYSVGNLASAIATCRQALELQPDWAPAYVTMGNVHQANGQLDEAMRLYSEAIALNPDFAEAYANLGSMLYKRGLLVEAIVNYEKAIVLKPNLAAAYWNLALALKQQGQFEAAVSYEQKALELNPHLAEVDFNLDLGDKLVRLGKLDEAVIAWQRAIDLKPDLPEAHCQIGIVLRYQGKFKQAIPHLEKALEIKPDFIPAHQHLCGILRDTNDLAVARQAVHKYSEMCGETDPIMTAIYFISTYQVSGLNQIAKDRFLELESYLQKNLDTFQSVEIKSLYANFLFSTPYLRDNLTANSQLYRTISRKYIEQCIKPNFPQVAHYSLKSNATAGQLKIGFLSNHFSRHSVGWCSADIIRELSEITPNLYLYASERIANDDRTQKFATFGKLTSPKIFTNSAEIIDKIQTDELDILVDLDSLSVPVHADILYCKPARVCVSWLGFDAAYISPKNYFLSDWHSHPEGREKYYDEQLIRMPDSFVAVSGFQRYGVDPVALRKSNRIGLDQIVYLCVAPGRKFNYDLVKAQVAILKQVPNSVLIHKALGDSAVFEAAYHQVCEAEGVSRHRIKFLPRVATEEEHRTVYLLADVLLDSYPYNGGTHTLEALWFNLPVVTRIGEQFLSRMGYSFLQTLGITTGVAWSWEEYVEFGVKLGKDSELRNWVKAQLVDSKKAGNLSPLWNAKKFAGDMYAVFQKLVQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUR1</accession>
    <name>A0A2G4EUR1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000253">
        <property type="protein sequence ID" value="PHX53170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53170">
        <property type="protein sequence ID" value="PHX53170"/>
        <property type="gene ID" value="CP500_022940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="142" mass="15740" checksum="10E48E9C56AB7EA7" modified="2018-01-31" version="1">MIARLGVISLTGEVEREELIAQLRAAGVKHNPDDILRIARLPDGKIVFLEIGNDGSGWQHIRKQHAENFAGRGIPEDQIIDAVIAAVINGRILGNQGRSRTVYEIDFNGAIQYISVEVANNGYIVGANPTRQNLIRRFTQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUS2</accession>
    <name>A0A2G4EUS2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridoxal phosphate-dependent aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000222">
        <property type="protein sequence ID" value="PHX53289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53289">
        <property type="protein sequence ID" value="PHX53289"/>
        <property type="gene ID" value="CP500_022315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="31"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="406" mass="44252" checksum="4D251F4CF7A068CC" modified="2018-01-31" version="1">MEFAERLQPLRSNVFADMDRAKFLARAAGKDVIDLSLGSSDLPVAAHIIDAIAHSLSDSSTHGYLLFNGTKSFREAAASWYEQKFGISVNPETEVLPLIGSQEGTAHLPLAVLNPGDFALLLDPGYPSHAGGVYLAGGQIYPMPLLAENQFLPVFDDIPKTVLAQSKMMVLSYPHNPTTAIAPLAFFDKAVAFCREHRLVLVHDFPYVDLVFDDAVGAVPPCPPSDSGKEEEYRKLKAPSIFQADRDKSVSIEFFTLSKSYNMGGFRVGYAIGNPEIIQALRQVKAAVDFNQYQGILNGAIAALTGPQDTVKTSVETFRKRRDTFVRALQNIGWQVPIPPATMYVWAKLPEPWALDSVKFCTQLVENTGVAASPGAGFGKSGEGYVRFALVESPEILAEAVRRIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUS5</accession>
    <name>A0A2G4EUS5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000221">
        <property type="protein sequence ID" value="PHX53293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53293">
        <property type="protein sequence ID" value="PHX53293"/>
        <property type="gene ID" value="CP500_022265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="365" mass="41440" checksum="38129779F464184A" modified="2018-01-31" version="1">MSRPTLYIAITNHGFGHAVRVSSVAAKIQELNPEILLIIATTAPRWLLESYITGDFILRPRAFDVGVVQSDSLTMDLDATLEKLQEIRHKQNSLIASEVNFIKQNRVGLVLADIPPVMTKIAKAAGVPCWMMSNFGWDFIYRDWGGEFDEIVDWIRECFGMCDRLFRLPLHESMSFFPNIEDVGLTGGNPRYSEEQIRELFRIETPPEKTVLLTFGGLGLEDIPYHNLHKFSDRQFITFDRSAPDLPNLIRVKSQEFAKSFPILPRPVDVMPVCGRLISKPGYSTFSEALRLEIPVVSIVREGFAEAQILLEGIQNYGEHQIVTTEEFFDGDWEFLRKPMNPPRLSDKLAINGTEAIAQAVVDYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUT4</accession>
    <name>A0A2G4EUT4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000230">
        <property type="protein sequence ID" value="PHX53248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53248">
        <property type="protein sequence ID" value="PHX53248"/>
        <property type="gene ID" value="CP500_022510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="129"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="163"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="256" mass="28048" checksum="A9B25440E94ECBB9" modified="2018-01-31" version="1">MKNDREFRLLKFFTWIIPSILGMGGIGALTVAPVVQAEPSTGQISQNLQAQNGQQPSPRSPVREVISYEMKGDELKICKQQGKSEKKCEVVAKGYTVALRTANDLYSQGNAANAEVLYRQLIARFPKQGDAYYKLGTLLSSQGKMSDAIAQFQKAIEVNPQHAKAHNDLGVAMASQGKLPDAIVQWRQAIKINSQYPDALNNLGVALYQQGAKEEQAEAVASLKKAQELFVKQGRVSQAKRVEQILQEINSQSSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUU6</accession>
    <name>A0A2G4EUU6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent dethiobiotin synthetase BioD</fullName>
            <ecNumber evidence="7">6.3.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DTB synthetase</fullName>
            <shortName evidence="7">DTBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Dethiobiotin synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">bioD</name>
        <name evidence="8" type="ORF">CP500_022110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring (By similarity). This cyanobacterium does not encode bioA (which catalyzes the formation of the precursor for this reaction in the cannonical pathway), instead it encodes bioU, which replaces bioA and also performs the first half of the cannonical BioD reaction. Thus in this organism BioD has a different substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(7R,8S)-7,8-diammoniononanoate + ATP + CO2 = (4R,5S)-dethiobiotin + ADP + 3 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(7R,8S)-8-amino-7-(carboxyamino)nonanoate + ATP = (4R,5S)-dethiobiotin + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:63684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:149470"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dethiobiotin synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.3" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000215">
        <property type="protein sequence ID" value="PHX53322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53322">
        <property type="protein sequence ID" value="PHX53322"/>
        <property type="gene ID" value="CP500_022110"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43210">
        <property type="entry name" value="PTHR43210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006755">
        <property type="entry name" value="DTB_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00347">
        <property type="entry name" value="bioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="7">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="108"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="168"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="200"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="233" mass="25586" checksum="2EFF8F7724E553D3" modified="2018-01-31" version="1">MNSLLITGTDTDAGKTVLTSALAAYWQMYFSDRTLGIMKLLQTGRGDRELYTRLFALDQSPEELNPLHFNAPLAPPIAAEREGRHIELEKVWTTLQSLNERKDFVLVEALGGLGSPVTRELTVADIARDWRMRGVLVAPVRLGAIGQIVANVALARHSGFKLKGIILNCVQAASEQEIADWAPIDLIESLTQIRVLGILPHLDAPNDLTKLAKAASQLDLERLLHGVNLIPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV34</accession>
    <name>A0A2G4EV34_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.191</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">lpxD</name>
        <name evidence="7" type="ORF">CP500_021730</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:53836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="EC" id="2.3.1.191"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the transferase hexapeptide repeat family. LpxD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000203">
        <property type="protein sequence ID" value="PHX53394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53394">
        <property type="protein sequence ID" value="PHX53394"/>
        <property type="gene ID" value="CP500_021730"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00523">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020573">
        <property type="entry name" value="UDP_GlcNAc_AcTrfase_non-rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04613">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LpxD" evidence="6">
        <location>
            <begin position="25"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="346" mass="36298" checksum="3EDDCD83031B50BA" modified="2018-01-31" version="1">MKFSEIVQKLNLVSSRSLTASVATDPEITGAAPVDEAASDKISYIEGAKFASHTTSTNASALILPLDESLQARCADRNIAWIATPDPRLLFAQTIALFYQPFRPTSEIHPAATIHPTAQIGENVYIGPHAVIQPGVKIGSNVCIHPNVVIYPDAEIGEGTVLHANCVIHERTRIGANCVIHSGAAIGSEGFGFVPTATGWVKMEQSGCTVLEDGVEVGCNSTIDRPAVGETRIGQNTKIDNLVHVGHGCQVGKNCAFAAHVGMAGGVKIGNNVILAGQVGIANQAKIGDGAIATAKAGIHSDVAAGAIVTGVPAIPHKLFLKAAAVYNRLPEMYQSLRQIQRKLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVF9</accession>
    <name>A0A2G4EVF9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MOSC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000200">
        <property type="protein sequence ID" value="PHX53420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53420">
        <property type="protein sequence ID" value="PHX53420"/>
        <property type="gene ID" value="CP500_021575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOSC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="126"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="273" mass="30096" checksum="C85C22E1B4D7C396" modified="2018-01-31" version="1">MTTATIKQLFTYPIKGLTPQEMSEFMLTAGHGIKGDRAFALMFADSMKAANIQAENAPWMSKKDLAVQNDWPLLAALECHYEPETAILTVKREGVGVLTAATNTAPGRDRISNFFTEYLTTIEPTKEARHPERVPLHLAGNSSGETRYPDRETVHISLLSQATLDQLTERAGENIDVRRFRPNIVLEGMAAWSEFELIGQHFQLGDAQIEVTARIGRCVNIEVNPETGDRDISLLSLLQQEFGHAQTGVLAKVINSGNVKIGDILTSIPVTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVG3</accession>
    <name>A0A2G4EVG3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000195">
        <property type="protein sequence ID" value="PHX53456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53456">
        <property type="protein sequence ID" value="PHX53456"/>
        <property type="gene ID" value="CP500_021415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="6"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="256" mass="29359" checksum="7EF132BA528038A2" modified="2018-01-31" version="1">MEHRRIVIGDVHGHYDGLMTLLEALALGWDDRVYFLGDLIDRGPKSAQVLEFVKESSYQSLLGNHEQLMLNALVDGLTDARSWQAWLCSGGDTTIDSYIETGMMPYKHLEWMRSLPTHLDLGDIWLVHAGVHPTIPIDQQSSEQLCWIRKEFHNISKPYFPDKLIITGHTITFTFEGVRPGELVRGQGWLDIDTGAYHPKSGWLTGFDLNYRRVYQVNVFNNQVRILPFDELVRPMKSQLIPLLKPVMSGVYSEYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVL8</accession>
    <name>A0A2G4EVL8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HicB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53583">
        <property type="protein sequence ID" value="PHX53583"/>
        <property type="gene ID" value="CP500_020795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9205" checksum="EF95FD96931113BA" modified="2018-01-31" version="1">MLTKYIQAAMKQAKYEIFPDDRTFYGEIPICEGVYANAVTLEACREELQEVLEDWILLGLTLNIPLPVLDNIDLTITKDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVY4</accession>
    <name>A0A2G4EVY4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CopG family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000167">
        <property type="protein sequence ID" value="PHX53648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53648">
        <property type="protein sequence ID" value="PHX53648"/>
        <property type="gene ID" value="CP500_020335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="205" mass="23498" checksum="B5D8CB947A758DBC" modified="2018-01-31" version="1" fragment="single">QNLESQLAETVAKSSYEVLQQQLTERESSIESLHSQLAEAKQNLESQLAEKQNLEQQLLTQLTERESSIAQLHSQLAEKQNLEQQLLTQLTERESSIESLHSQLAEAKQNLESQLAEKQNLEQQLRTQLTERESSIESLHSQLAEAKQNLESQLSQSVAKQRNYDALQQQSQEQLRTIKTLREQLSQMQAVAGIGEAVLNKWRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWE3</accession>
    <name>A0A2G4EWE3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Penicillin-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mrdA</name>
        <name evidence="5" type="ORF">CP500_019810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53760">
        <property type="protein sequence ID" value="PHX53760"/>
        <property type="gene ID" value="CP500_019810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017790">
        <property type="entry name" value="Penicillin-binding_protein_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03423">
        <property type="entry name" value="pbp2_mrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="4">
        <location>
            <begin position="75"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="276"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="604" mass="65414" checksum="62F3D9677FB66ADF" modified="2018-01-31" version="1">MASDFSFKSQVKFEKNGLDNTVRQRGRSLKVMVFMLLVTTLVTLPLFRLAELQLVQGAYNRQRAENNRIRPVSVAAVRGQILDRNQKIFATHRVSRSVYLWPKERSPQEWQEAVAILSPIVNIPATEIIQKIDKAGYKSALPVRISKDINIATFIALGEQANTLRGVEIRPESGRDYPNQQLASHLLGYVGEATLDELKANPGYPMGMIVGKMGVEKLVNPTLEGVWGSRLIEVNAKGEEIQDLGVKEPIAGKPVQLTLDLDMQKTAEKALGNRLGAVVAIDIKTGALLTMGSWPTFDPNIFTRKLTQKEWDRLQGPDKPFLNRAVQGYPVGSTFKIVTSVAGMESGKFSPDSTLLSSASINIGGISFNEHGSGYGTIGFRDALAYSSNTFFYQVGMAAGPEQMSKWASKMGIGGTINLDILGLDAANHGQVPTPAQKKKMYGEDWYVGDTVTMSIGQGLVLCTPLELAVMVSTIANGGWRVQPHLLASQTNTPITQKIQTGIKPATLKVIREGLIDVVLKGTGRGMNDGTIPLSAGKTGTVEIPGHPDNSMYVGFAPADKPEVAIAVIVEGGGFGAVSAAPIAHEVFRTYFQKQGFKPIVKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWZ2</accession>
    <name>A0A2G4EWZ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SGNH/GDSL hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53986">
        <property type="protein sequence ID" value="PHX53986"/>
        <property type="gene ID" value="CP500_018610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="410" mass="46347" checksum="6CB578469A8A8345" modified="2018-01-31" version="1">MSKLKTLGVNLGLTLGGLLMGVIIGEAALRIGGIQGYPKIGDIVDSAPTGFHTSDQNLGWKLKPGVSGEWKGEGASFLQVNSEGLRDREHTKIKPPNTLRVAVLGDSFTEALHVPIEQTFWSKLERKLGNCQAVKGRKNVEVINFGVQGYGTAQELIMLRKKVWDYNPDIVVLAFFVGNDIINNSPKLEYDRYRPFFVYDASGKLVPDMSFRNLRPTERNLYAVSFIDKLPTWLVNNSRILQVVKKVELDRKKQQLSNDFTNLSGQNFKEPTDATWQNAWKVTEGLIVTMRDEVVQKNADFLVVTIGDPIQIHPDAAIRKKFIKENNIQDLFYPNRRLEKLGITNGFRVLSLAEQFQGYTDKYQVCAHGFENYINCGGHWNELGHRLSSIMISRNLCENLKQSQSQKSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX07</accession>
    <name>A0A2G4EX07_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DUF1049 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_018100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54082">
        <property type="protein sequence ID" value="PHX54082"/>
        <property type="gene ID" value="CP500_018100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010445">
        <property type="entry name" value="LapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06305">
        <property type="entry name" value="LapA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="LapA_dom" evidence="7">
        <location>
            <begin position="22"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="14264" checksum="029186BE4EB5CC27" modified="2018-01-31" version="1">MRVLNFFFIFLICLALVLFSIENTEPTTIQIIKGFQVKAPLSVELIMATGLGAILAWVFSLWSRMQRMLVSRVETRQVREKEQQIKSLEQDIKRYRGEVESKQPLLESAESSTVEDAKSTIAIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX15</accession>
    <name>A0A2G4EX15_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phospholipid carrier-dependent glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_018085</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54073">
        <property type="protein sequence ID" value="PHX54073"/>
        <property type="gene ID" value="CP500_018085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="80"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="553" mass="62739" checksum="2B837AC58A003589" modified="2018-01-31" version="1">MSEIFPPSTEKYTSRLNDHSTDKLWMLAWMLAAVLIFGLNLGGVALRDWDEGIAAQVSREIWGGKLNWLYPTIGGMPYFNKPPLVHWLIGLCFAAGGVSEWTARLIPAMLTATSVPLLYAIGRELFPRRSIAIFSTLVYLTLLPVVRHGRLAMLDGAVLCFLLLSMWCLVRSRRDLRYALGAGISFGLICLTKGVMLGMLLGAIGFLFLIWDTPRLLTSRYLWGGLAIGTLPVVGWYFAQWVHYGQDFINTNLVSQSFRRIGETVSNHKGPPWYYLLKILESAWPWQLFWLQGLRLTWENRNFPGQKLVLVWSGVYLLAISVMNTKLPWYILPIYPVVALAVGSYLAEVWEQMWLREEPETEEVEKYFDAVSLLPHPAILGVLAVVAIVGCIYFSGLVPIGKYIVPREGDLQLMLMFVALTMTISAVLLHRKDRQFLLVLIWGTYVTLLVFVASDNWVWELAEDYPVKPVAEIVRTGTPAGQQVFTSHRFPRPSLNFYSNHQVIVADGPTLQQKWQTLSQPYFLLDKSVFKHLALKNAKVVKTVDDWVLVTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX41</accession>
    <name>A0A2G4EX41_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Coproporphyrinogen III oxidase</fullName>
            <ecNumber evidence="6">1.3.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemG</name>
        <name evidence="8" type="ORF">CP500_017925</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:43436"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="1.3.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.15" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000125">
        <property type="protein sequence ID" value="PHX54099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54099">
        <property type="protein sequence ID" value="PHX54099"/>
        <property type="gene ID" value="CP500_017925"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="7">
        <location>
            <begin position="14"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="481" mass="51757" checksum="ED4903AC2BF4C0C9" modified="2018-01-31" version="1">MTNVVDSLIVGAGITGLSLAHALHKEAKTGTPVKILVAESLGRVGGNITTCTGNGFLWEEGPNSFSPTVELMKLAVDVGLKEELIFADRKLPRFVYWQNKLQPVPMTPQAMIQSQLLSFPGKLRALFGALGFVAPAMGATLSQQGGQETISQFFRRHLGTEVMQRLVEPFVSGVYAGDPEQLSAAAAFGRVTRMADLGGGLVAGALLGARKGPKKMPADPNIPKTKPGELGSFKGGLKALPEAIAAQLGDRLKLNWHLTGLHRTENKTYIAEFSTPDGPQQVETRTVVLTTPAYVTADWFQSLQPEVSTALQAFTYPTVACVVLAYPKSDVKEKMVGFGNLIPRGQGIRTLGTIWSSSLFANRAPAGWQTLTSFIGGATDSGIANLDAEQIVAQVHRDLSRILLKPDVPQPKVLAVKVWKQAIPQYNLGHFDRLEQIDRGLKSLPGVYLCSNYLGGVALGDCVRLGLERAIEVSKYLQETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX90</accession>
    <name>A0A2G4EX90_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycos_transf_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000119">
        <property type="protein sequence ID" value="PHX54162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54162">
        <property type="protein sequence ID" value="PHX54162"/>
        <property type="gene ID" value="CP500_017560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="237"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="431" mass="48843" checksum="BA45CAF920797919" modified="2018-01-31" version="1">MSLMQVNSNNSEQLDKTQDLEFLEPITKRYLMVMNIRSTCDKKGDRYLDPLWAKDLTEHFRYLKNFTLASPCQQERSPENTIDVEKEPSFADVEFIDLPSPNSYKEAILTLPATVAKLWGAIGQADIVHSCVTGWPIPMGWLVTPIVLIQGKFYVLVVESAPWRLEPGTTIKIKDRIIAYVSEIVNRWCVNNANLTIFTQSEYQQSLLTKRKERGHVIHASWIDEENIISEADAAEIWQKKLSPSTQKLKLLFAGRVETSKGVLVLLEAMKILDNKNIAINLDILGDGTLLSECKTLSSQLQKSVNIRFLGTVAYGKELFRMLQKYHAIVVPSISDEQPRIVYDAYSQAVPVLASNTDGLRDCIQNYKTGVIVNSNDPVALADLIEWSGQNLPQLQSMGKASLQEAHSLTHQEMHRKRWQLLLKMLEQSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX91</accession>
    <name>A0A2G4EX91_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperonin GroEL</fullName>
            <ecNumber evidence="6">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Chaperonin-60</fullName>
            <shortName evidence="6">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">groL</name>
        <name evidence="6" type="synonym">groEL</name>
        <name evidence="10" type="ORF">CP500_017640</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54149">
        <property type="protein sequence ID" value="PHX54149"/>
        <property type="gene ID" value="CP500_017640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="479"/>
            <end position="481"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="546" mass="57873" checksum="358F0B27EA9FC408" modified="2018-01-31" version="1">MAKRIIYNENARRALERGMDILAEAVAVTLGPKGRNVVLEKKFGAPQIVNDGVTIAKEIELEDHVENTGVALIRQAASKTNDAAGDGTTTATVLAHAMVKEGLRNVAAGANAIALKRGVDKATTFLVGKIAEHAKQVEDSKSIAQVGSISAGNDDEVGQMIANAMDKVGKEGVISLEEGKSMTTELEITEGMRFDKGYISPYFVTDTERMEAVLDNPFILLTDKKIGMVQDLVPVLEQVARSGSPLLIIAEDIEKEALATLVVNKLRGVLNVTAVKAPGFGDRRKAMLEDIAVLTGGQLITEDAGLKLENTKLDMIGKARRITITKDSTTIVAEGNEVAVKSRCEQIRRQMDETESSYDKEKLQERLAKLAGGVAVIKVGAATETEMKDRKLRLEDAINATKAAVEEGIVPGGGTTLAHLTPQLEEWANSTLTGEELTGALIVARALAAPLKRIAENAGLNGAVIAERVKEKPFNVGFNAATNEFVDMFEAGIVDPAKVTRSALQNAASIAGMVLTTECIVVDKPESKDGAPAGAGGGMGGGDFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXJ1</accession>
    <name>A0A2G4EXJ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54249">
        <property type="protein sequence ID" value="PHX54249"/>
        <property type="gene ID" value="CP500_017085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="13851" checksum="8B3AE9951B6DBA66" modified="2018-01-31" version="1">MVLSENRYQRYQELQEALEQLKRIAAQDNLERAELAVEYRKVQQFFGNQIMRADSGELDELGTPPEQSYLTEIHKQLRMFGTDVTFLQASRQPATVTGRQTAAIARLNTLIGYCGALLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXK0</accession>
    <name>A0A2G4EXK0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c-550</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytochrome c550</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Low-potential cytochrome c</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">psbV</name>
        <name evidence="12" type="ORF">CP500_016960</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="9">Binds 1 heme c group covalently per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The cyanobacterial oxygen-evolving complex is composed of PsbO, PsbP, PsbQ, PsbV and PsbU.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Lumenal side</orientation>
        </subcellularLocation>
        <text evidence="9">Associated with photosystem II at the lumenal side of the thylakoid membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the cytochrome c family. PsbV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54263">
        <property type="protein sequence ID" value="PHX54263"/>
        <property type="gene ID" value="CP500_016960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018063">
        <property type="term" value="P:cytochrome c-heme linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01378">
        <property type="entry name" value="PSII_Cyt550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029490">
        <property type="entry name" value="Cytochrom_C550"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016003">
        <property type="entry name" value="PSII_cyt_c550"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017851">
        <property type="entry name" value="PSII_PsbV_cyt_c550"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14495">
        <property type="entry name" value="Cytochrom_C550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005890">
        <property type="entry name" value="Phot_II_cyt_c550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03045">
        <property type="entry name" value="PS_II_C550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="5 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013976285" description="Cytochrome c-550" evidence="9">
        <location>
            <begin position="26"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="11">
        <location>
            <begin position="49"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX54263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="17937" checksum="0C94DD1DD842AD49" modified="2018-01-31" version="1" precursor="true">MLKRYFIALTAVFLTFQLFVSSAMAVELSPKLRTVTLNDKGDPVELSLKQVKQGKRLFGSTCAQCHNSGMTKTDPNVNLSPETLALANPPRNNVESLVDYMKNPTTYDGFEEIYETHPSIRSADVFAEMRNLSDDDLYAIAGHILLQPKIIGKQWGGGKGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXQ0</accession>
    <name>A0A2G4EXQ0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54313">
        <property type="protein sequence ID" value="PHX54313"/>
        <property type="gene ID" value="CP500_016695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="192" mass="21925" checksum="EF9D9EA395870C68" modified="2018-01-31" version="1">MIAQVETKTYTAQEYLEAEVNSLDRHEFINGEIILMAGGTPDHNEIALNLGGALKLALKGKPYRTFSSDQRLWVPQLNNYTYPDVMVVAKPIELQSGRTDTITNPLLIAEVLSKGTRAYDRDEKFAAYRSIPSFQEYLLIDQYRLQVEQYSKTDANKWIFSEYGVIGDRLMLTSVQVEIAIADLYENIEFNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXX0</accession>
    <name>A0A2G4EXX0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000104">
        <property type="protein sequence ID" value="PHX54385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54385">
        <property type="protein sequence ID" value="PHX54385"/>
        <property type="gene ID" value="CP500_016370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13098">
        <property type="entry name" value="Thioredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="38"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="22623" checksum="D101AEC16923B147" modified="2018-01-31" version="1">MIFSKYQNLIATAASGLGLWRRIVSASLLTVAIALSFILLTGTAPAYATLTDDRFDGTIYALYAGNGSLVPPKVKLTDSFKRQKPALLVFYTDDSSDCKQFAIVVSNLQEFYGREADFMPIFVDSLPPEASPKLTEPSHYYKGFVPQTVLLDQSGKVVYDAKGQVPFEEVDEAFRKVFDLLPREKSLPLKRRVVNELNIELSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY01</accession>
    <name>A0A2G4EY01_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Regulatory protein RecX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RecX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54330">
        <property type="protein sequence ID" value="PHX54330"/>
        <property type="gene ID" value="CP500_016785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003783">
        <property type="entry name" value="Regulatory_RecX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33602">
        <property type="entry name" value="PTHR33602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02631">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17958" checksum="70071BCC3ABC959A" modified="2018-01-31" version="1">MSCLDYFYFLLSRKDYSASELRKKGQEKGFGNEQMLEAIAQIQDRGYQSDTRLVANSIASAAGKYGKSAVKRKCLQKGIPSDLFEQVWEEESAENVDSEAEKLAELKAKVMRKYKIDAWDKVDPKTKGKVLNYLQYRGFNAFEIWRQWQMEEADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY88</accession>
    <name>A0A2G4EY88_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54494">
        <property type="protein sequence ID" value="PHX54494"/>
        <property type="gene ID" value="CP500_015770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="23451" checksum="C1A29FD1B3C9EB50" modified="2018-01-31" version="1">MPKIYTQAELINILEAERQACLHGRRLNLAETDYTGNPVIDRFLKSEGVQKFTAYQNFKAAVHEYQREHQVSGIVWREMTVKGNTLSYPAVEDELIALPIDLMTLKSAKISMLEFWRQVTLGMDLYLSINSGKDFRAIEPIDVEAIVQRTEWASLWKWEKLDFLEILLQLGWGKPEEAYYKRGWPTSGSEYIHAVKPGQKPIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYB6</accession>
    <name>A0A2G4EYB6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000119">
        <property type="protein sequence ID" value="PHX54167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54167">
        <property type="protein sequence ID" value="PHX54167"/>
        <property type="gene ID" value="CP500_017595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023981">
        <property type="entry name" value="MftF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43646:SF6">
        <property type="entry name" value="PTHR43646:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="12"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="337" mass="38127" checksum="620352145A3AFB43" modified="2018-01-31" version="1">MKEIGLVAIGRNEGQRLRQCLVSATNKVVRVVYVDSGSTDGSLELARSLGADTVELDLSTPFTAARARNEGFARLLELAPDIEFVQFVDGDCELVDGWLDRAYSELTAKPNVAAVCGRRRERYPAATIYNQLCDIEWDTAIGETTACGGDSMIRTAAFQQVEGFNPTLIAGEEPEMCLRLRQKDWKILRLDAEMTLHDAQMTNFTQWWKRSQRAGYAYAEGSWMHGKKPDRHWVKETKSIWLWGLIIPALALTMALPTKGWSLLLLTGYLLATYRTYNYYLKHRDITTKNAAIYAFSCILAKFPQLQGQIQFHQRRLLGQQSKLIEYKTTKPLNSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYF2</accession>
    <name>A0A2G4EYF2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endonuclease MutS2</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mutS2</name>
        <name evidence="11" type="ORF">CP500_017450</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54197">
        <property type="protein sequence ID" value="PHX54197"/>
        <property type="gene ID" value="CP500_017450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00092">
        <property type="entry name" value="MutS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005747">
        <property type="entry name" value="MutS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF14">
        <property type="entry name" value="PTHR11361:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005814">
        <property type="entry name" value="MutS_YshD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SSF160443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 7 11" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="10">
        <location>
            <begin position="825"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="713"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="619"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="376"/>
            <end position="383"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="898" mass="98225" checksum="7D876ACEEB30D11F" modified="2018-01-31" version="1">MPITNNPSTLIQSETLELLEWSRLCQHLATFAATKLGVAAALDLEIPPTQAQTAELLAQTQEAYQLDNRPGAALAFEGIQDIGQALQRAELQGLLSGEELLAIATTLAGARQLRRIIDNQPDVPTLKELAAGLRTYPEIEQEIHRCIDDRAQVADRATPKLAGIRVQMRQLRDRIYQILQGILQRQSNAVQEQVITQRNARFVIPVKAPQKDAIPGIVHDSSASGATLYVEPHNTVNLNNQMRQFLRQEQVEEEAVRRALTEQVGAVKPDLDRLVVVVTTLDLATAKARYGFWLQANPPTFIELGNTKLTPKDGEIAEEENLENSKVQIPNLRSQITLRHLRHPLLVWQQQYEQGFAVVPIDLTIAPHIRVVAITGPNTGGKTVTLKTLGLAALMAKAGMFVAAREPVELPWFDNILADIGDEQSLQQSLSTFSGHIRRISRILAVLKKGGEEDSDLPIPHTSTTLRLRSGDTIPDTSTTLRLRSEDTVPDAPCPMPHAQFPIPKSLVLLDEVGAGTDPSEGSALAIALLQYLAQNSLLTIATTHFGELKALKYQDSRFENASVEFDDSSMQPTYRLLWGIPGRSNALSIAKRLGLLPEIVAEAQTHVGGASVDVNQVIAGLEAQRRKQETKAREATQLLHATEQLHREVSEKAAALKERERELKIAQEVAVNEAIGTAKSEIAQIIRRLQSGDQTAQNAQVATETLNQISAKHLPSRKEPAKPKPGFMPKVGDRIRIPSLGQTAEVLSGPDANEELSVRFGIMKMTVKLAEIESLDGQKPETKAQLAKIAAQAQAQATAKAKQAQSEVAKPNPEIAIRTANNTIDLRGARVSDGEIEVDRALSKAVEYGVLWIVHGKGTGQLRRGIHEFLDTHPQVSRYELASQKEGGGGVTIAFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYH2</accession>
    <name>A0A2G4EYH2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54510">
        <property type="protein sequence ID" value="PHX54510"/>
        <property type="gene ID" value="CP500_015705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="161" mass="17468" checksum="3A7B08F9F5B4A038" modified="2018-01-31" version="1">MLWFRFLTVEELRSCTILNQPFTGGQDAHPTRNSLFVEQAGKPVADNAHPTRNSLFVEQAGKPVADNAHPTRNSLFVEQAGKPVADNAHPTRNSLFVEQAGKPVADNAHPTRNSLFVEQAGKPVADNAHPHKKLTLCGTGILPVHENSATSQEKGSYKLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYI0</accession>
    <name>A0A2G4EYI0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Branched-chain amino acid ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_017325</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54227">
        <property type="protein sequence ID" value="PHX54227"/>
        <property type="gene ID" value="CP500_017325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013585870" evidence="2">
        <location>
            <begin position="22"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="3">
        <location>
            <begin position="56"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="418" mass="44299" checksum="20C480A4A2334C83" modified="2018-01-31" version="1">MKKPTPRSSALFITCASLLLACSQTNTPQTSTTASPGTSPSADTSPQGSAGGNSNTIYIGIGVAQTSNVALLGQEQVAGAKIAEKYFNDKGGVDGTPIKLVFQDTGGDEQGAINAFNTLINQDKVVGIVGPTLSQQAFSADPIADRAKVPVLAPSNTAKGIPQIGDYIARVSAPVAVVAPNAVKAALKQNPNIKKVAVFFAQNDAFSKSETETFQTTVKDMGLELATVQKFLTTDTDFQSQATNAINVKPDLIIISGLAADGGNLIKQLRELGYKGVIIGGNGLNTSNVFAVCKALCDGVLIAQAYSPEYENEINKAYREAYRAQFKKEPPQFSAQAFTGVQVFVDSLKAINAQSKVSQKPLAELRTNLNQQLLGGKYDTPLGEISFTPEGEVNQKEFYVARIKMEADGNNGKFEFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYI9</accession>
    <name>A0A2G4EYI9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF1232 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_015255</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54594">
        <property type="protein sequence ID" value="PHX54594"/>
        <property type="gene ID" value="CP500_015255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010652">
        <property type="entry name" value="DUF1232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06803">
        <property type="entry name" value="DUF1232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1232" evidence="6">
        <location>
            <begin position="31"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14205" checksum="3B859EED4F5D0345" modified="2018-01-31" version="1">MQSLKQLARKLKKETYAIYLASIDPRVPWYARMLAGVTVAYAFSPIDLIPDFIPILGYLDDLIIVPLGIWLVIKMIPPQILAECREKAATEIERGKPINRAAAVVIVAIWIGFGILTAICLKQIFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYL9</accession>
    <name>A0A2G4EYL9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type II toxin-antitoxin system HicA family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_015410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HicA mRNA interferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54570">
        <property type="protein sequence ID" value="PHX54570"/>
        <property type="gene ID" value="CP500_015410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038570">
        <property type="entry name" value="HicA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8446" checksum="92A9771B42902369" modified="2018-01-31" version="1">MPRKIRDYKAELIALGFAQRRGKGSHQNWKHPQLQLLITIAFKDGEDTPLYLDKLLKKAIQELEIIAAEESEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYP3</accession>
    <name>A0A2G4EYP3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative pterin-4-alpha-carbinolamine dehydratase</fullName>
            <shortName evidence="4">PHS</shortName>
            <ecNumber evidence="4">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pterin carbinolamine dehydratase</fullName>
            <shortName evidence="4">PCD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_015075</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54645">
        <property type="protein sequence ID" value="PHX54645"/>
        <property type="gene ID" value="CP500_015075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00434">
        <property type="entry name" value="Pterin_4_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTHR12599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="SSF55248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013646580" description="Putative pterin-4-alpha-carbinolamine dehydratase" evidence="5">
        <location>
            <begin position="23"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="150" mass="16339" checksum="9A1728124DBEFA62" modified="2018-01-31" version="1">MRTSVLSISLAIAAIAISPTTAAVVGEPIITKSIAQTTENSNLKHLSEQEISQRLQALPNWTRDGKTIKYTHEFKNFVESVSFVNCLISPSEKAGHHPDIAIAYNRVTISLTTHDAGGLTKQDFELAETISKLVSEWMPGNVCLVMEGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYQ8</accession>
    <name>A0A2G4EYQ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54317">
        <property type="protein sequence ID" value="PHX54317"/>
        <property type="gene ID" value="CP500_016720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8508" checksum="827F920E60F51EA7" modified="2018-01-31" version="1">MTLKELIYEEINKLEEENLKELYEVVKRFTQIKSTQPKLGALAKLKRVKIQAPVDFTANLDLYINGEKEIDPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYR8</accession>
    <name>A0A2G4EYR8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_014905</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54671">
        <property type="protein sequence ID" value="PHX54671"/>
        <property type="gene ID" value="CP500_014905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="34"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="335"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="377"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="419"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="461"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="503"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="545"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="586"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="622" mass="69121" checksum="1AA209FD9B5AA46E" modified="2018-01-31" version="1">MSYCLNPSCSKPQNPDAAKLCKNCRSKLLLRDRYRAIKPIGQGGFGRTFLAVDEDKPSKPRCVIKQFLPPEVALIPSASNRNSKKAAELFEQEAMRLDELGKHPQIPELLAYCIQDSRQYVVQEFIDGQNLAQIVATEGIFTDNQIQDLLNSLLPVLHFIHSHNVIHRDIKPENIIRRADKELVLVDFGAAKIATGTALLKTGTSIGSPEYIAPEQARGKAFFTSDLYSLGVTCLYLLTQVSPFDLFDPGEDVWIWRQYLANNPITEELGKILDKMIENATNRRYQTAVEILKTLNPQAAINLTVTPTISKPDQPTFIHNSSQQPTFKWQCIHTLTGHKNLISSVAFSPNGEVIASASDDKTIKLWRVQDAQEITTIAGHTNSVHTVAFSPDGNILASSSHDKTIKLWGMKDGQEICTLAAHGNSVYGVAFSPDGEILASSSWDRTIKIWRVKDGQEVRTLTGHINLVYGVAFSPDGEILASSSWDRTIKIWRVKDGKLIRTLTGHTDCVRCIAFSPNGEFLASGSHDNTIKIWWIKDWQEVLSITGHSWYVDSVAFSPDGETIASSSNQTIKIWQVKDGQEVCNITGHTNSVYSVNFSPEGDFMASGSSDRTIKIWHKVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYX0</accession>
    <name>A0A2G4EYX0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10 11">Photosystem II reaction center protein Z</fullName>
            <shortName evidence="10">PSII-Z</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">psbZ</name>
        <name evidence="13" type="ORF">CP500_014535</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cellular thylakoid membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="10">Associated with the photosystem II complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10 11">Belongs to the PsbZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54723">
        <property type="protein sequence ID" value="PHX54723"/>
        <property type="gene ID" value="CP500_014535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042549">
        <property type="term" value="P:photosystem II stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00644">
        <property type="entry name" value="PSII_PsbZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002644">
        <property type="entry name" value="PSII_PsbZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036512">
        <property type="entry name" value="PSII_PsbZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34971">
        <property type="entry name" value="PTHR34971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01737">
        <property type="entry name" value="Ycf9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161055">
        <property type="entry name" value="SSF161055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03043">
        <property type="entry name" value="PS_II_psbZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10 11" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9 10 11" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="3 10 11" id="KW-0674">Reaction center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10 11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX54723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="6793" checksum="A08C03BCE0165373" modified="2018-01-31" version="1">MLSILFQVVLLGLVLLSFVMVVGVPVAYASPQNWTQSKTLIFAGSGLWFLLVIAVGVLNFLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYZ5</accession>
    <name>A0A2G4EYZ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54720">
        <property type="protein sequence ID" value="PHX54720"/>
        <property type="gene ID" value="CP500_014510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="9096" checksum="CB45CE407869EB4E" modified="2018-01-31" version="1">MKTAISLPDPIFEEAEVLAQKLGISRSELYTEALKVYLRRYNRERILSKLNEVYSQESSDLDTVMTTMQLLSLPQEDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ10</accession>
    <name>A0A2G4EZ10_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate/guanylate cyclase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54427">
        <property type="protein sequence ID" value="PHX54427"/>
        <property type="gene ID" value="CP500_016215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="384"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="621"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="879" mass="98703" checksum="7EA6F135B7AAF297" modified="2018-01-31" version="1">MTFSNVGSVLATLTQVNLMGALTSRVKNLPVPELVCLLDFITAEFQQFIRAMDLINNEALESLLEQLLDAFTIKIGLILQADRTTIFLVDSSKNQLWHKTVDVNGNNLEVRLPMDAGILGYVASTGESLNVLEARDHEQFNPEVDEPPDYRIKTILCMPIFSSKSETEPVAVVRLLNKAGDSPFTEEDEQQFRVFADSIGIILESCQSFYVVARNQRGVAALLRATTTLGQSLDLETTLRSVMDQARDLMQADRSTLFLLNRETNELWTRVAKADGKTMVSLRIPANRGIAGYVASTGQILNITDAYDDPRFDPSTDQQTGYRTRTVLCMPVFNAKGELIGVTQLINKNQGTFTNSDEEFLRAFNSQAGMALQNSQLFENMMVEKQYQKDMLQSLSDAVISTDFQGRIVTINEAALELLGCPVNQDKTKDNPQLWEEKLINRYVWDVLPIENLQFRLQDSLNHAARHYVPEQNLTIGLLVEKSLNPQEEDNYILAVPAPNNPNLYYAWGENDAWTEELAQLKLANSQSLFALDNSATYYPYCPLPISRSQIKIIERSLNLTVNPLTNPEGGVRGGLVVLEDISREKRMKTTMSRYMTPGVVEQVMALGDDALMVGERKDVTILFSDIRGYTTLTENLGASEVVALLNQYFETMVEAVFHCEGTLDKFIGDALMAVFGAPLPLNPPESHGWMAVKSALDMRKRLQEFNDSRPGEIPFRFGIGISSGEVVSGNIGSQKRMDYTVIGDAVNLSSRLEQLTKEYGCDIILSEFTYSLCRDRIWVRELDKVRVKGKNQPVGIYELLQSSSEPIDGETQKFLELYKNGREAYISRNFQKAISFFEAALVMRPNDKPVEVHMERSLSYLEVSPPEDWDGVHTMTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ55</accession>
    <name>A0A2G4EZ55_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54776">
        <property type="protein sequence ID" value="PHX54776"/>
        <property type="gene ID" value="CP500_014230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="176" mass="18201" checksum="AD5D3F7CB30400BE" modified="2018-01-31" version="1">MEGVPKMVARSNSQTPAPFSFQPLSGFVFLAAILTLSTTAAKAQLRVGDSMSCGQVRMHGGMGGVGFSGQTMNICIPNSTLQNSFRRTSNRGADLTIQPTTCGTGAATGVIPISFGGGNGMFVEGGIMLDQMFPMNRNGGGCPPMSVIMQLAGECSRGDRDACGGLNRIRRAGCAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZK7</accession>
    <name>A0A2G4EZK7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54928">
        <property type="protein sequence ID" value="PHX54928"/>
        <property type="gene ID" value="CP500_013495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8571" checksum="97BAB96EC471B637" modified="2018-01-31" version="1">MVQAQFNLDESLWAFVQRSRQYGFQNQDELIRVALGKLQQELDSLEMSADLYTEVYAEDADLQALTDSAIAGWPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZK8</accession>
    <name>A0A2G4EZK8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54943">
        <property type="protein sequence ID" value="PHX54943"/>
        <property type="gene ID" value="CP500_013380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010802">
        <property type="entry name" value="DUF1400"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07176">
        <property type="entry name" value="DUF1400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1400" evidence="1">
        <location>
            <begin position="52"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="24558" checksum="C10111CAF1F8697E" modified="2018-01-31" version="1">MNFQFQSDYLDGMPQQSAYLTKKMSKSLSLGLALLLGTSAVLLSSGKALALEKVTVKYGAVDVTLPISDLQSFAQTGKPSPQLQSVLSLAKQTPESVREILTREVVLDTQLVTRLANTYFGEIVLKQLGEVAYAPATRAQSAPALRDALVAASKDSKISLIEVMQNYSPPALEIDGNQAMAVYQRVIKDVQDLQAMYQNSPALQSTAGQAVNSARQMICQPNSSGNMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZN4</accession>
    <name>A0A2G4EZN4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54971">
        <property type="protein sequence ID" value="PHX54971"/>
        <property type="gene ID" value="CP500_013190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="9386" checksum="351DF977ABD8815B" modified="2018-01-31" version="1">MSIEHHRRDTNSQLAKVAKVAKVGTAILGTKVAMTVVTTLVAAILATKVAMTAVTKMATAILSTKMATAILSTKMATAILSTEMVTAILGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZQ1</accession>
    <name>A0A2G4EZQ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid oxidation protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54985">
        <property type="protein sequence ID" value="PHX54985"/>
        <property type="gene ID" value="CP500_013260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="16149" checksum="BFCD489AF50C9392" modified="2018-01-31" version="1">MPAKDVFHQIVISALKKDGWTIINDPLFLKLSRQTEFFIDLAADKLLIVERQKNQIAVEIKSFIGRSTIAEFHMAVGQYLNYRLALQKVGSARVLYLAVPQDTYREFFADSFVEEAVEQHQLKLIVFNPKQEEIVLWKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZZ2</accession>
    <name>A0A2G4EZZ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chloride channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_012505</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55089">
        <property type="protein sequence ID" value="PHX55089"/>
        <property type="gene ID" value="CP500_012505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="Cl-channel_volt-gated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="SSF81340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="457"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="520"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="903" mass="97046" checksum="5A4829243B2BE606" modified="2018-01-31" version="1">MPHIPIPKQFRESSKVIESQLFLQPKRLAIFEACLIGLISGLAGVLLKLGVGWLGSWRVATSTVIPAFILLPSVGLLGGLLTGFLVERWAPETSGSGIPHVKAALAGVNLSLNLRVAVAKLLTTILAVGSGLTLGRQGPTVQIGASLASWIGHLMPTSPDYRRQLIACGAAAGLAAGFNAPIAGVLFVVEELLHDVSGLTLGTAIIASFIGAVVSQLLGGDSLNLNLREYQTSFAAQEIPFYILLGVLAGLLGALFSKGIIAGLQFNRKTLKLALPWRVALAGLICGLVIAALPENFRNNTGLREFLLTGEATGKTSLIAFVAHFFLTIISAASGAPGGLFAPSLVLGSALGHIVGILQADWLGVGLPVTYALAGMGAFFCAVSRAPITAVVIVFEITADFKLVLPLMICSVVAYLVAEKVDSGSLYDRLLELKGIQLTKDKPAVDALSDLYAANVMQRQVETLSSLLTFDEVMQAFSRSHHRGFPVVDGGKLVGIVSQSDLKNAKDRNFTGQFLLKEFMTPQPITVKTNDTLSEVLYRLNNYNLSRLPVTEGRRLVGIITRSDIIRVESDRLSGETTQGPHPEPSYVVYQTRAPQLGNGRLLVPLSNPYTAPALLRLAATIARDRNYELECLQIMLVPRNSSPSETAVRTTKSRRLLQQAERIARHWNVPLHTQIRVAHDVPSAILETIGERHIDLILMGWQGEISTTGRIFGDVVDTVIRQAECEVILVKWSEKLLQKGQKGDGHPKSKTAEISAPHSNIESEELGLHTLMGLQRWLVPIRGSYKQAAALRLLPAFVAASEVPEIKLCQVHQPSVAAPDRHELKQAAEFLKRRVSCEVVATSVCAKSVSDALIDLAHNDQCDAIVLGASREGLLKQVIQGNIPEAVARGCECTIILVRSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F053</accession>
    <name>A0A2G4F053_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphate acyltransferase</fullName>
            <ecNumber evidence="3 4">2.3.1.274</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Acyl-ACP phosphotransacylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Acyl-[acyl-carrier-protein]--phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phosphate-acyl-ACP acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">plsX</name>
        <name evidence="5" type="ORF">CP500_012135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>a fatty acyl-[ACP] + phosphate = an acyl phosphate + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.274"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Probably interacts with PlsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Associated with the membrane possibly through PlsY.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PlsX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.274" evidence="3 4"/>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55128">
        <property type="protein sequence ID" value="PHX55128"/>
        <property type="gene ID" value="CP500_012135"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043811">
        <property type="term" value="F:phosphate:acyl-[acyl carrier protein] acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00019">
        <property type="entry name" value="PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003664">
        <property type="entry name" value="FA_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012281">
        <property type="entry name" value="Phospholipid_synth_PlsX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30100">
        <property type="entry name" value="PTHR30100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02504">
        <property type="entry name" value="FA_synthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002465">
        <property type="entry name" value="Phsphlp_syn_PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00182">
        <property type="entry name" value="plsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="349" mass="36837" checksum="5771D00111916BDD" modified="2018-01-31" version="1">MGSTRARIAIDAMGGDHAPAEIVAGALKAQAELGVEILLVGDPQQIEDSLREQDALGRVCAGQLEIVASEGTVEMHEEPLSALKRKPKASINVAMNLVKQQQADAVVSAGHSGAAMAAALLRLGRLPGIDRPAIGAVLPTMVAGRAVLILDVGANVDCRPKFLEQFAAMGTIYSQYVLGVAEPRIGLLNIGEEPSKGNDAAVRTHQLLVDNPHIPFVGNAEGRDVLSGKFDVIVCDGFVGNVLLKFAEAVGEVVVQVLKEELVKGLQHQINDPLLQKSLQGFKQRVDHVEHGGGLLLGVAGVCIISHGSSQAASIANAVRLAKGAIDNQVLERIQSEYRQSPVEQEVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0I3</accession>
    <name>A0A2G4F0I3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55271">
        <property type="protein sequence ID" value="PHX55271"/>
        <property type="gene ID" value="CP500_011530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="27"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="219" mass="25067" checksum="0D7F84012A39DCA8" modified="2018-01-31" version="1">MVTTTSTPVEQQITPENRVVLKGVSWSTFKALVADVGDDRAWRIAYDRGVLEIRMPLEEHEEPKRLIESFVEAIVDELEIELRSLGSLTLEREDLTRAVEPDSCFYIQNESVVRGRNINLPNDPPPDLAIESDYTNSSVNKDAIYAALGVPELWRYQRQSLQVYQLVEGKYQKCDRSLAFPFLPVAEIPGFIEQSRTIGQRSAVRLFRQRIREILLSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0I4</accession>
    <name>A0A2G4F0I4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gfo/Idh/MocA family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55265">
        <property type="protein sequence ID" value="PHX55265"/>
        <property type="gene ID" value="CP500_011500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="145"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="387" mass="42594" checksum="C0B1B8BBF511BE19" modified="2018-01-31" version="1">MSKIGVAVVGTGFGQKIHIPGFQAHHRTEVVAVYHRNLDKAQAIASSHNIPYACNSIEDIIAIPEVAGVSISTPPFLHFEMAKKVLEAGKHLLLEKPTALTANEARELYQLADKSQTNIESKSAKTIATMDFEFRFIPAWQMLAELLATGYVGEKRLIKIDWLVSGRADANRPWNWYSQKERGGGVLGATGSHVFDYINWLFGPIQRLSGQLITGISMRPDPNDSGKLKPVDADDSCTLMLELAEGIPCQVCLSSVTYQGRGHWVEIYGSKGTLVLGSDNQQDYVHGFRLWGSQGGQPLAEIKIPQRLEFPQVYPDGRIAPFIRVVDKWVEAIDGGESLIPSLRDGVYSQLLMDLTQESNATGTWVDIPNLDKFLSSNINSGNTGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0K1</accession>
    <name>A0A2G4F0K1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55289">
        <property type="protein sequence ID" value="PHX55289"/>
        <property type="gene ID" value="CP500_011625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044200">
        <property type="entry name" value="At5g03900-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47380">
        <property type="entry name" value="PTHR47380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="434" mass="48628" checksum="EE8DAA23CCB3E317" modified="2018-01-31" version="1">MAPNPKVMQAVKELGYRVTVGDVAAKAGLDVNFAQRELLTLASEAGGHIQVAESGDIAYLFPQNFSDVLRNKFLRLQLQEWWQKIWRVLFYLIRISFGLVLVASLLLIFVAIAILLSSSSDNNDGGGGGGGDRGGGFFFFPYFGNDLIWLFYWNHDESYYQRRSRSTGQKPEMNFLEAVFSFLFGDGNPNYNLEDRKWSSIAATIRNNKGAIAAEQIAPYLDNLGQGYAIEYEEYMLPALARFDGRPEVSPEGQIVYHFPQLQTTATERNSEPVAAYLREMLWRFSHASSGQIMLAAGLGAVNLVGALFLGSLLTKSAIGSGLLSLVATIYPMLLIYGVGFLTIPLVRYFWIKWKNSSIEARNQERQQRMMLLNEPDANLLQKLAYAREFAAENVLTGEDLAYTTETELTAQELEQSAKIDAEWQKRIGRSDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0L5</accession>
    <name>A0A2G4F0L5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55303">
        <property type="protein sequence ID" value="PHX55303"/>
        <property type="gene ID" value="CP500_011645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="68"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="240" mass="26976" checksum="65BB8AAE0E7B6D81" modified="2018-01-31" version="1">MEIIPPKIDYEGAWDSYAQEWKENNPELAYLGDEWIGKGAGAANSLSEYESLIEQEFIAPYIKKEHTVLEIGIGGGKTGSLLLRYCDRLICADISTQMLQATRSRLGSDRVSYVKLNGLTLDGIAPESADVCFCYDTMVHVEPVDIFNYLTRIPKLLRGDRICVFHHANILSELGWQKFASEWDKNLLGRRDGTAFSVMTDTIMEKFLNHLNYEIILKNTSSVPRDCVWICKAPLVSSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0M5</accession>
    <name>A0A2G4F0M5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55310">
        <property type="protein sequence ID" value="PHX55310"/>
        <property type="gene ID" value="CP500_011435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8024" checksum="C2980A3C4947C0A0" modified="2018-01-31" version="1">MTIEKFVVTADQMRQIEARIFAAGMPVAALMEKVAGLLARRIQALVKEEGRGKKGEGPSITLRVQKGMRDLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F113</accession>
    <name>A0A2G4F113_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ComF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55449">
        <property type="protein sequence ID" value="PHX55449"/>
        <property type="gene ID" value="CP500_010740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="226" mass="25647" checksum="E6C33223568C951F" modified="2018-01-31" version="1">MNQRKWTGFVKSLLNLFLKSNCPLCQRPATAELCPYCDKQLQRCQLADPSRLWDSQKAVFVWGEYGGALKRAIAAFKYENNPQLGKPLGCWMAEAWLNYPELAIDNLTVVPIPLHKEKLKERGFNQAELLAQSFCDLTGLPLQRQGLERVKYTQPLFELSAQERQAEMKDALILGKDFRRRLPRDRVLLVDDIYTSGTTVRSAIKVLKQSGISVYGTIALASPKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F114</accession>
    <name>A0A2G4F114_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55443">
        <property type="protein sequence ID" value="PHX55443"/>
        <property type="gene ID" value="CP500_010705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="393" mass="44949" checksum="7F36969D6AFEF6E9" modified="2018-01-31" version="1">MREICQSVETIFQLLLDELKKSTRASEQNCQNVAGRLAAEVNRICTESQRIQASGDIEGSAQGLAQHRLQQCLHYYDLGSGPGRIELHSTLSAIVYRYITPPQVQSSYQARIELIKDFLQGFYLEALKAFRRETQLPTTYTPRTRLELAEYMAFVERFGKRRIPLPRNRSQQLIILRAQTFSQQQPKETSVDMEQAADGGANDSDQTWNDSSVHSVREAMAGQGSAAIRPNGEESESLRQNVIDELVAYLKERNQSECADYFVLRLQDLPTQEIEAILGITPRQRDYLQQRFKYHLLRFAMSHRWELVHQWLEADLDRNLGLLPAEWQTFGEQIGPEGQRLLKLKQQGLSDSAIAQTLSSTVAQVQKRWFKLLELAWELRNRSDSGEGASSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1A4</accession>
    <name>A0A2G4F1A4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55532">
        <property type="protein sequence ID" value="PHX55532"/>
        <property type="gene ID" value="CP500_010540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="241" mass="25420" checksum="4F92CE57A8F4886C" modified="2018-01-31" version="1">MNYPTTKQALITGASSGIGKATALAFAKAGINLALVSRESENLAAVAAAAREVGVKAEAYPLDLSKIEQVQSSISAIAAQFGPIDILVNSAGMGYTGPLTETPLADWQRVLDLNLTSVWQCIQGILPGMRDRKSGIIINVSSIAGSQVFPNWGLYCVSKFGLMALSKAVATEERVRGIRVTAICPGSVNTPMWDTETVQADFDRTAMLTPEIVAESILHTVQLPASAVIEEITLMSNAGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1C1</accession>
    <name>A0A2G4F1C1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55546">
        <property type="protein sequence ID" value="PHX55546"/>
        <property type="gene ID" value="CP500_010190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="253"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="477" mass="54072" checksum="E365266136282D84" modified="2018-01-31" version="1">MSEIEKVLNPNVYAFAFHLIGDASGKDNPLWNWGDDFLESFTSEKLKPKLNFSEESSNFRVDLLPEISLGFNTKVSYNETKLDVSGFAKPIKIGDSYALWLNVGFPDSFVGEVSPQWLSTFNPGNLLGIVTGEEFIGETILITAKLPPQPQPPSLDNLQSLADKCCNALLPEKYRPPFNRAGELFGSPIFEYGLIKQTANYRHLLVWFPNSEASEDKLGTYQQEIIDLFYYRNKIIKAFHNSRQIHRILLDFYRQVEDNVNCLQQRIDELGSDLTTENLQEFKEELKKLLKTALTYTQGLTKLEDYDNTIAINLNNYDEKFAQIYAKVESDKEEPSILNHFSRKTAPYMRSQIAGDLGYFRHGTNLIDQAIASIRGIVEIEQARSDRTNQIELRKSELGEKNRDDRLQSTVQAIGVGLAAGGIAASSGTDEVFQTVQNYKIPVLMQLHPFLFSFALSFAIALFAASITWWRTKPKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1C8</accession>
    <name>A0A2G4F1C8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55555">
        <property type="protein sequence ID" value="PHX55555"/>
        <property type="gene ID" value="CP500_010235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="7345" checksum="1BEB1AA38E331803" modified="2018-01-31" version="1">MQQIKDTSLFTEITAQESASVNGACYRRRYYSSRYDSYRPRRHIVYRRNCNGTLRAVVSYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1E2</accession>
    <name>A0A2G4F1E2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4058 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55566">
        <property type="protein sequence ID" value="PHX55566"/>
        <property type="gene ID" value="CP500_010060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025132">
        <property type="entry name" value="DUF4058"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13267">
        <property type="entry name" value="DUF4058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="267" mass="30470" checksum="A4FCE27401B30218" modified="2018-01-31" version="1">MPSPFPGMDPYLEHPDFWQETHNRLIVAIADTIMPQIRPKYEVAIDKRIYEITDPNDSNGDSLLVGIPDVAIKRQSNSPNISTSSVATLTITLPTTVKVPAPAKITQTYLEVREMTTKQVVTAIEILSPVNKRSGEGRITYLKKRQSILGSLTNLVEIDLLRKWESMPILNNSIQSDYRVLVSPSNRRPFAELYAFNLRDSLPIFPLPLREEDVEPIVNLPEIFAGIYDRAGYDYRIDYDREPVPSLSEEDRVWATQFLPEKELRDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1E3</accession>
    <name>A0A2G4F1E3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bifunctional protein GlmU</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">UDP-N-acetylglucosamine pyrophosphorylase</fullName>
                <ecNumber evidence="15">2.7.7.23</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">N-acetylglucosamine-1-phosphate uridyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Glucosamine-1-phosphate N-acetyltransferase</fullName>
                <ecNumber evidence="15">2.3.1.157</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15 17" type="primary">glmU</name>
        <name evidence="17" type="ORF">CP500_010145</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="15"/>
    <dbReference type="EC" id="2.3.1.157" evidence="15"/>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55581">
        <property type="protein sequence ID" value="PHX55581"/>
        <property type="gene ID" value="CP500_010145"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03353">
        <property type="entry name" value="LbH_GlmU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01631">
        <property type="entry name" value="GlmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005882">
        <property type="entry name" value="Bifunctional_GlmU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038009">
        <property type="entry name" value="GlmU_C_LbH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01173">
        <property type="entry name" value="glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14 15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="16">
        <location>
            <begin position="5"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyrophosphorylase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="89"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="15">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="259"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="15">
        <location>
            <begin position="393"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX55581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="50209" checksum="0AB06A77361D8CDB" modified="2018-01-31" version="1">MIAIAVLAAGRGTRMKSDLPKVLHQLGGRTLVERVLNSCQEIEISRRLVIVGYRSELVKKSLLGNQELPATENQQFPLLEFVEQTEQLGTGHAIQQLLPYLKGFPGDLLVLNGDVPLLRSQTLKHLVETHQQHQNSATLLTANLPNPQGYGRVFTDSQNLVEEIIEDRDCTTPQKQNCRINAGVYCFHWPHLEKVLPGLKADNNQQEYYLTDTVKFMNPVMAVDVADYQEILGINDRKHLATTSDILQQRIKDQWMAAGVTMIDPNSITIDDTVELQANVVLEPQTHLRGKTAIASGSRIGPGSLIENSQIGQNVTVLYSVISDSIVSDNSRIGPYAHLRGHAEIGANCRVGNFVELKNTQIGDRTNVAHLSYLGDATLGEKVNVGAGTITANYDGVNKHKTTIGDRTKTGSNTVLVAPITVGEDVTVAAGSVVTEDVPNDCLVVARARQVVKPGWKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1E5</accession>
    <name>A0A2G4F1E5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">(2Fe-2S)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55558">
        <property type="protein sequence ID" value="PHX55558"/>
        <property type="gene ID" value="CP500_010255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12062" checksum="1155CB1DA4591C9E" modified="2018-01-31" version="1">MVKVQAQGKTFECDRGANLREVLLKNGIDLYNGNATIINCHGLGTCGTCAVNVEGEVSEPQWRETTRLALPPHSPASNRRLSCQTQVLGDIKVTKYDGFWGQGSETVWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1I4</accession>
    <name>A0A2G4F1I4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55609">
        <property type="protein sequence ID" value="PHX55609"/>
        <property type="gene ID" value="CP500_009935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="53"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="296" mass="32237" checksum="3D548F6F50B68FB3" modified="2018-01-31" version="1">MPASFLPKSIAQLTESTSIALAQSIQQEAITTPLTSGPIATTYVHQGSGNTPILLIHGFDSSVFEFRRLLPLLAEKNETWAVDLLGFGFTERVAGLPFSAMAIGSHLYYFWKTLISQPVILIGASMGGAAAIDFTLNHPELVKKLILIDSAGFAITANNGKFLIPPLGYLATSFLRNPKIRQKISVNAYFDKTLASVDAQTCAALHLEVPNWNQALIAFTKSGGYCGFGEKLSEIQQQTLILWGKQDRILGTADATRFESAIANSQLIWIPDCGHVPHLEKPQITAQHILEFVSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1M3</accession>
    <name>A0A2G4F1M3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TlyA family rRNA (Cytidine-2'-O)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_009645</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TlyA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55663">
        <property type="protein sequence ID" value="PHX55663"/>
        <property type="gene ID" value="CP500_009645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004538">
        <property type="entry name" value="Haemolysin_A/TlyA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32319:SF0">
        <property type="entry name" value="PTHR32319:SF0"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00478">
        <property type="entry name" value="tly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S4" evidence="3">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="385" mass="41177" checksum="F755C412A97A60F5" modified="2018-01-31" version="1">MAKQRLDTLLVNLDLCTSRQQAQALIRTGKVTVNQQVVDKPGTEIDMAANIHIKERSRYVSRGGEKLAKALQVFAIPVTDRICLDGGISTGGFTDCLLQAGAAKVYGIDVGYGQADWGLRNDPRVILKERTNLRYMTAAELYGDSPPPTPPCQGGEPDSAAPTPPCQGEEPDSAAPTPPCQGEEPDSAAPTPPCQGEEPDSAAPTPPCQGEEPDSAAPTPPCQGEEPDSAAPAPKGGEPDSAQSPALSIGVYADLAVVDVSFISLDKILPALWELLAPPREAVLLVKPQFEVGRERVGKKGVVRDSATQADAIFQVWKAARALGWEERGLTWSPLLGPAGNIEYLLWLGGDRQQQSEQNTVEESVMKERIAEVTQAAKRELIDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1V5</accession>
    <name>A0A2G4F1V5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Succinate--CoA ligase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_009215</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55729">
        <property type="protein sequence ID" value="PHX55729"/>
        <property type="gene ID" value="CP500_009215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="7">
        <location>
            <begin position="9"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="407" mass="44258" checksum="DAB5C19CCEDC6337" modified="2018-01-31" version="1">MDLLEYQAKALFRQMEIPVLPSQRIDNPADLKGLKIPYPVVLKSQVRAGGRGRAGGIKFVENTIDAVAAAQTIFNLPIESEYPQVLLAEAKYNADQELYLAVLLDPVARRPVLLGSQQGGMDVEGSIDKMQQVVVDQEFSPFYARRLMLKMGLQGNLIQSVSTIVEKMYRLFVEKDLDLVEINPLGINPKGEVMALDGKVSANNDALGRHPDLVALGAKKQDTKLPGERRSQTERLRANSNLLHSSLELAPTSPSQISNSEPLNLVELDGNIGILCNGVGLTMATLDAVVQEGGKPANFVNLGSLDRYDSVDALRDRAELALELVSQDKSVKVVLVNILASTTTSEAIIAAVVGYLERKTRANRQLQIVLLLVGIDRDAVKKRLGQLHVQLASTLDQAVAQAVSQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Y1</accession>
    <name>A0A2G4F1Y1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KGK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55774">
        <property type="protein sequence ID" value="PHX55774"/>
        <property type="gene ID" value="CP500_009050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014971">
        <property type="entry name" value="KGK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08872">
        <property type="entry name" value="KGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="15784" checksum="144776D375C2F52B" modified="2018-01-31" version="1">MKSPQIFLQEDDVLSTPASALMYQCTFKVSEFLTIMQSKLLEERLFLDGMDCELLSSGKSWTKGKVIVRLEFCPDEDQIEQKALPAASEHSDSTQEYNQNSSGQIDANQNSNAGESTEINTNFPIYRHRNSNPHSVGMWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F202</accession>
    <name>A0A2G4F202_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Urea ABC transporter ATP-binding subunit UrtE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">urtE</name>
        <name evidence="5" type="ORF">CP500_008940</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55803">
        <property type="protein sequence ID" value="PHX55803"/>
        <property type="gene ID" value="CP500_008940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017780">
        <property type="entry name" value="ABC_transptr_urea_ATP-bd_UrtE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43820:SF5">
        <property type="entry name" value="PTHR43820:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03410">
        <property type="entry name" value="urea_trans_UrtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="232" mass="25468" checksum="B61D79BF42581DA8" modified="2018-01-31" version="1">MLQVSNLNVYYGESHILRNVDLSVKPGQMVCLIGRNGVGKTTMLKTLMGLLQPRSGTIDFGGQSIVSKLTHQRAKMGIGYVPQGREIIPRLTVKENLLLGLEAKPTRTKNPEVPDEIFDLFPVLKTMLTRLGGDLSGGQQQQLAIARALMGEPQLLVLDEPTEGIQPSIILDIEAAVRRVVATRGISVLLVEQHLHFVRQADWYYAMQKGGIVASGNTSELSDEVVQRFLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F224</accession>
    <name>A0A2G4F224_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">recQ</name>
        <name evidence="12" type="ORF">CP500_010505</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55527">
        <property type="protein sequence ID" value="PHX55527"/>
        <property type="gene ID" value="CP500_010505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006293">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029491">
        <property type="entry name" value="Helicase_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018982">
        <property type="entry name" value="RQC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14493">
        <property type="entry name" value="HTH_40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09382">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00956">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01389">
        <property type="entry name" value="recQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="36"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="230"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="HRDC" evidence="9">
        <location>
            <begin position="532"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX55527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="731" mass="83193" checksum="554CA97A96415865" modified="2018-01-31" version="1">MSGSNLPTSPVPPSLEHHLKHFFGYDSFRPGQREIVEAALEKRDQMIVMPTGGGKSLCFQLPALLKPGLSVVVSPLIALMQDQVEALVDNGIGATFLNSTLNSLEARSRETAILEGKIKLLYVAPERLLGERFLPFLDIVAAKLGISAFAIDEAHCVSEWGHDFRPEYRQMERVRDRYPDIPIMALTATATERVRQDIIQQLTLRNPYIHVASFNRPNLYYEVRAKNKHSFAEVLKIIQKKGGSGIIYCLSRKKVEEVAYKLQQSGIQALPYHAGMSNVDRTTNQTRFIRDDVQVMVATVAFGMGINKPDVRFVIHYDLPKNLEGYYQESGRAGRDNEPSHCTLFFGFGDVKTIEYMLELKPDPQEQRIGRQQLRRVINYAESTDCRRTIQLSYFGDSFPGNCGNCDNCCNKKPVEDWTVEAMKFLSGVARCKEKFGMNHIIDILRGSKNQKVLQYQHDKLSTYGIGKDRSADDWKMLVRSLLNQGLLDETTDGFPILKLNEKSWEIMKRQRTVEIAIKPKQEVQATNRSLAVEVESLFAILRTLRKQIADEQFVPPYVIFADKSLRDMAEKRPQNLTEFVKVYGVGSNKRDKYGKVFLEAIRNFCQEKGLPTGAAPSAIVQSSNVPNLPSYTQMQTWELHRKGLTVEGIAEIRGMSSTTIVGHLVELIDMEQKVDIHLLVEPERQQPIVQAIEIIGDERLKAIYEFLQEAYSFEEIKLVRAWWRQNYVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F249</accession>
    <name>A0A2G4F249_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55547">
        <property type="protein sequence ID" value="PHX55547"/>
        <property type="gene ID" value="CP500_010195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="12864" checksum="1BE0FB8616603B05" modified="2018-01-31" version="1">MKPEKIIASFLVVLKTSPNLFTEAATEAMKALEKDIMAAENESNQAISKILSNWCIDYPEVTKALESVATRSKAIPKASQPQGDENISENQFPRLFPRLLESLEKRIKSEKPENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F292</accession>
    <name>A0A2G4F292_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CpeR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55866">
        <property type="protein sequence ID" value="PHX55866"/>
        <property type="gene ID" value="CP500_008520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="12175" checksum="84A06B3386FDC904" modified="2018-01-31" version="1">MVLPPIADKKMQAWIRSRHLIFTGQFLIFETLDYPTVERFEECITSLGGCLISVEPTKRVWMGNHRQVMLYQAKGSLHTPHHELRQYWFKYGSFQTRFDERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2P5</accession>
    <name>A0A2G4F2P5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56044">
        <property type="protein sequence ID" value="PHX56044"/>
        <property type="gene ID" value="CP500_007635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8158" checksum="3FAC533A2588640F" modified="2018-01-31" version="1">MPSAYILLLIVSLVAIWVYWQTSQDIFVLVALAGVGCFIWGFSCSPWIVQLLIVLLLLGVPNNYLRDSRSWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2R7</accession>
    <name>A0A2G4F2R7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Photosystem II protein PsbQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">psbQ</name>
        <name evidence="3" type="ORF">CP500_007405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56050">
        <property type="protein sequence ID" value="PHX56050"/>
        <property type="gene ID" value="CP500_007405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009579">
        <property type="term" value="C:thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023222">
        <property type="entry name" value="PsbQ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017487">
        <property type="entry name" value="PSII_PsbQ_cyanobac"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101112">
        <property type="entry name" value="SSF101112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03042">
        <property type="entry name" value="PS_II_psbQ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0793">Thylakoid</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013639786" evidence="2">
        <location>
            <begin position="28"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="16481" checksum="0A6146E527897B48" modified="2018-01-31" version="1">MTRSRSFFALIMSFMMAFLVSCSSVEAKVPTTYTAAQVQQIQRYVPSLTELRSRMDNLGTLIEKRNWIDTRTYIHGPLGDLRGAMKTVSASLLPKSQQQAVDLTKSLFADLVNIDLAAKDFDYAKVTSSYQKAVNDFDAFLQLIPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2T7</accession>
    <name>A0A2G4F2T7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phycobilisome maturation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56058">
        <property type="protein sequence ID" value="PHX56058"/>
        <property type="gene ID" value="CP500_007445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="207" mass="21669" checksum="370D455B159C7E7B" modified="2018-01-31" version="1">MTNQLIQAVEQADSSEGLLNAVKALAAADLTEAIPTLITVLGYNNPGAAVAAVDGLIQIGEPAVQPLLEQLDGYNYGARAWAVRALAGIGDPRGLDILLDAAANDFALSVRRAAAKGLGTICWELMPIEQIAEAQGNTSKTLLQASQDPEWVVRYAAVGGLQALAGAAVQPDWLSAVLTRLEEIVSGDETSSVRARAWVAQQKLLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F366</accession>
    <name>A0A2G4F366_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56175">
        <property type="protein sequence ID" value="PHX56175"/>
        <property type="gene ID" value="CP500_006955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="246" mass="26173" checksum="FE86C07C0011D9C1" modified="2018-01-31" version="1" fragment="single">ISSPSPNPSLPSIAISQTPVTNKPSPIQQPALLFPANSTPSAAPNAAPNSQGQVITIPAPPELPISAPSQLPPARNVIPPVPPRLGPIAAPPLPPSLSAQFPTPQQPSALSRIQPILPPASSELPALQDTQPKSESDDKQASASKTNRTLFDTVPQVSEAKTYFEERWKPTEGMQETLEYSLQIDETGSIQNILPMGKAAGDYIDRTNMPLVGEPFVSAVSNGKPPRIRVVLRPNGRVQTFLEESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F387</accession>
    <name>A0A2G4F387_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56219">
        <property type="protein sequence ID" value="PHX56219"/>
        <property type="gene ID" value="CP500_006540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8331" checksum="D60C7614B7A2F5CE" modified="2018-01-31" version="1">MIVTCLIPLSLFLVAAVITTGTDRRTLDGIPAPIAAIIGVFSLIWFVAVCPWPIELGLVLVVLVWGKAYVRDILRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3J0</accession>
    <name>A0A2G4F3J0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56322">
        <property type="protein sequence ID" value="PHX56322"/>
        <property type="gene ID" value="CP500_005920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="361" mass="39147" checksum="DC1B19D9484CD935" modified="2018-01-31" version="1">MDFSDILNSTETYLKNSVAANAELIDSDSEALKKAFVGLEERSLLALRVPQKWGGVDMDAESFYEYQELTARYSGALGFLQTQHHSATSMLANSDNELLKSRCLCAIALGELRLGVGFSHLRRSSSRASLTGNPAVTATPAKDGYLLSGQVPWVTGFGLFHKFIVAAVLPDDRAVFGLLPLANIASESGIIACGEIMPLIAMNSTNTVTVNLTNWWLDESQIISVKPKDWIVENDRKNVLNFVPATFGCIRAGLDIIEAVAEAKNSDSIADACQRLENQLDRLKQNFPQSQYSSTAEKLALRAQAIDLAVRCGHAAVVVSSGAANGQMHPAGRVYREALVYTVSGQTKDVMAATLDRLIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3M6</accession>
    <name>A0A2G4F3M6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prfB</name>
        <name evidence="6" type="ORF">CP500_006000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56335">
        <property type="protein sequence ID" value="PHX56335"/>
        <property type="gene ID" value="CP500_006000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004374">
        <property type="entry name" value="PrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00020">
        <property type="entry name" value="prfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0488">Methylation</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="5">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="4">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="363" mass="40854" checksum="45AE519C583D665B" modified="2018-01-31" version="1">MKHCAIAWVKLRTIFDIPALSAKIQDLEQIAAQPAFWDDQNQAQETLQELNDFKSHLDQYHGWQTSLEDARAILELLELEADESLFQEATSSLSQLTRELDSWELQQLLSGPYDQSGAVLTINAGAGGTDAQDWTEMLMRMYTRWGESQGYKVHLTEISEGEEAGVKSVTLEIAGRYAYGYLRSEKGTHRLVRISPFNANDKRQTSFAGVEVMPILDRNVKLDIPEKDLEITTSRAGGKGGQNVNKVETAVRIVHIPTGLAVRCTEERSQLQNKEKALTLLKSRLLVIAKEQRASEIAEIRGDMVEAAWGQQIRNYVFHPYQMVKDVRTGVETTAIVDVMNGELDPFIQAYLRQENQLVAQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3U6</accession>
    <name>A0A2G4F3U6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56453">
        <property type="protein sequence ID" value="PHX56453"/>
        <property type="gene ID" value="CP500_005485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="32613" checksum="89F94E3168B1E5CB" modified="2018-01-31" version="1">MTVDEAIAIAETVLDGEGLNDVQELIFRQCWEGRCSYEEISQLSQYNDEYIKALAAKLWKQLSQAFDEKVKKNNLRSVFKRYLQRHQVTLHRTQVIGVNLSGANLSGARVSFANLSEYDSSTDLQGATISDNKTVSDQIIKAEDAHNQGILSSIKSRIYHWNDLRFHCEEQVKIAEALDRTNTLFFPNSKARLTTPAGRQNQEPDFLIFHQGKWGILEISHPDTAKDETRDRDFASHGITIIHYCDAERCCEDADRIVQEFLDILSQSTMQNTENLHPIVLNPVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3V4</accession>
    <name>A0A2G4F3V4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56463">
        <property type="protein sequence ID" value="PHX56463"/>
        <property type="gene ID" value="CP500_005275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="81"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="313" mass="34968" checksum="5C73E551028C4412" modified="2018-01-31" version="1">MGWSELIYVGMGLGLGLGSNLILRPRQKSSQPLEPLSHQPSTPQEIYLEKFDGLSEQLKQTQLAYQMASEMSQFKAGFLARTSHELRSPLSSMIGTLQLILSDLCDDAAEEREFVEQAHVAALKLVKLIDQILFVAKTEHGTETMDIEPIQLAKIFDEVDDLTFLQAANRNIRLEISPPDSEIYVLADIPRLRQVLVNLIDTAIAEMEEGSIVVSAHPSPESGYVNIWVDDQRSISAWSESWDLLKHDLESDTNSSDTDTPKVSSGMRLLMDQTLLTLMNGRLEVLAVPCETEESNFTRTQCSIPLAKQSFME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Z9</accession>
    <name>A0A2G4F3Z9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nuclear transport factor 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56207">
        <property type="protein sequence ID" value="PHX56207"/>
        <property type="gene ID" value="CP500_006780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="323" mass="35783" checksum="09421DDE08514291" modified="2018-01-31" version="1">MRNFLNLVPSVSEYLTSHRDKKADRWLPLPAPLSPSALRLRSGFRMNSGFRMNSVEGSIAPFLIFLTVISASALHPVAVRAQGVRETNPQIQAQTRANAPAELTKLLTEIDAAANRRDVKAVMAFYGQNFTHSDGLNSQNMEKALTQLWQRYPSLNYRTEIKSWKAEGSATVAETVTTIAGTQKKDGTDLNLKATIRSQQRFEGQKIVKQEILAEQTQVSSGMNPPTIQVNLPEQVKVGEQYHFDAIVREPIGEDILIGTALEQPVSEKTFFKPSEVELELLNSGGIFKVGKAPATPENRWISAVLMRKGGITTVTVRLRVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F415</accession>
    <name>A0A2G4F415_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56489">
        <property type="protein sequence ID" value="PHX56489"/>
        <property type="gene ID" value="CP500_005210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="469" mass="52614" checksum="A952C2EA42533BC4" modified="2018-01-31" version="1">MPAHNPLLATQESAAFSAISRYLAQTLVSIQSKHPEWIAEKYRKTQWAKPDFQSILIVKFTKSFRLATDADSILLTAKKYLQILLIPEFVNSPQFSKIIAKIQQLAESQIPRVKSNNSVPSKPSTPSPSSIPSGDVGIAILLLDVENLQLNIETEKFLEGICHYPIQIKVAFANWRSMGKKDAEFHQRGYQLIHVPPGKDSADLKMATVGASIFVNYPTAKEILVCSSDRALTHLSNTLQAHGLTVFQVRKQLDKIIVLNSKTGQVETHSLVSLPEIEPIEKIVFQLKELIKIEQERTSAQWVKLSRISALFKENYGLTLNQVVASNLLGTKSRDIFIKYPTEFVVHHPSDTSQAYVTLFEVKLPPKSPILSKESSHKNIEEPTRLESINSLEDLETAIVKIVSDLTGNSPANSVFLSNVGSEFHRQYGKQITQIIKEFNLSRKFPKFLQSCTSLEIKKAEKGWQVSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F462</accession>
    <name>A0A2G4F462_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">High light inducible protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56525">
        <property type="protein sequence ID" value="PHX56525"/>
        <property type="gene ID" value="CP500_005080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="7864" checksum="8C6CF8DF86D8C459" modified="2018-01-31" version="1">MTNKGLILDDDGKMNNFAIEPTVYVDDQQRIGFTPYAERLNGRLAMIGFVSLLALEVSTKHGLITWLTHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F465</accession>
    <name>A0A2G4F465_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid oxidation protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56552">
        <property type="protein sequence ID" value="PHX56552"/>
        <property type="gene ID" value="CP500_004700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="16016" checksum="018F710F112E65FB" modified="2018-01-31" version="1">MAAKDRFHDAVKQALLKEQWVITADPLILKIDKVKFEIDLAAEKVFAAEKAGQKIAVEIKSFLNTSAVTDFHSALGQFLNYRLGLQMNEPDRTLYLAIPLDIFESFFQERFTQEAVRHYQVKLIVYEPIQEVIIEWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4I7</accession>
    <name>A0A2G4F4I7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56693">
        <property type="protein sequence ID" value="PHX56693"/>
        <property type="gene ID" value="CP500_004165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="563" mass="64929" checksum="C4874633F6F5C977" modified="2018-01-31" version="1">MIDRINHELLNLLPPDAKVIVEIGCGTGATGAQYKLTNPHCQYIGIECDREKAKIAVDRLNWVAIANIEQTDIASLDIAPGTVDCLIFGDLLPYLKNPWDILKQYSVLLNPEGQVFAKIPNVQYWRRIVHLLRGQWENPEGKMQHWFTLERIKSLFAEAGLQVYELQGKGQKNDNFAQFQELLHPMVKALELESSSFATETGAEYYIVRSSSRASLTTKTPLQPRRLLIQTIIMAPTGCDRVRVLEPDKFSATIPGVRTISAVKTTELIAPLPAEEKVFVWQRTIMQYPAYIPRLKQLLQQGYLIVAEIDDNPIRRREYADNNYLSYRGCHCVQTTTEPLAKALRQYNPNVAVFANQLAILPPPRTYSEDAITIFFGAINREKDWQPIMTALNRVLVAHKHRIRVKVIHDRLFFDSLEIEHKEFESFCSYERYQEIMYSCDIALLPLVSNPINEMKSDLKFIECAARGVAVLASPTVYENSIVEGETGLIYRHEKEFEIKLNMLISDAQTRRKIAGNAYEWVRDNRLLCGHYRQRRDWYLQMRDELPRLNAELRDRLPELFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4J8</accession>
    <name>A0A2G4F4J8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_004010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56668">
        <property type="protein sequence ID" value="PHX56668"/>
        <property type="gene ID" value="CP500_004010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="93"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="127"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="161"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="195"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="229"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="263"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="297"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="407" mass="46161" checksum="C4BC90365F7572E5" modified="2018-01-31" version="1">MQTLASMEKPIDRGGTSIELNPQDPQTWYDRGNALEEMGMLQPAIESWDKAIRLEPRFYEAWYNKGVALRKLGQLEEAIAAYDQSLKIKPDHPEALYNLGNVLGKCNRLSEAIASYEKAIEFKPHYHEAWSNRGNALVKLERFDEAIASYDKALTIQPDYWEAWYNKAFSLKKSGQNDKAIAAYDKAIELQPDLHQAWYNRAVALADAKRYLEAIADYDKTLQLRPKSPAAWNKRGTAIAQIGKFAEAIDSWDKSLALKPDNSEAWYNRGLALANLQQYSEAIASWDKTLERVPDNIDAWYNRAVALKKIERFAEAIASYDKIIALKPDDPNLYYQKAGIYALEKAASESKNQPEAALASMTDKAIANLRKAIELNPKKYLKICQNDSKFNTILEEVRSLALTQGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4S0</accession>
    <name>A0A2G4F4S0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BrnT family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56750">
        <property type="protein sequence ID" value="PHX56750"/>
        <property type="gene ID" value="CP500_003830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038573">
        <property type="entry name" value="BrnT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007460">
        <property type="entry name" value="BrnT_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04365">
        <property type="entry name" value="BrnT_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10511" checksum="CFFECB469ED2B922" modified="2018-01-31" version="1">MQFEWNLDKANLNLKKHGVSFNEASTVFNDPLSVTFPDPDHSYGEERYVIIGLSSVSRILVVPHTDRADRVRIISAREATRKEQRFYEDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4S6</accession>
    <name>A0A2G4F4S6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Primosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56497">
        <property type="protein sequence ID" value="PHX56497"/>
        <property type="gene ID" value="CP500_005225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PTHR23222"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="27"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="189"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="289" mass="31654" checksum="7C9DD67453489E28" modified="2018-01-31" version="1">MKNQNFQNISSAIAGILLVVALLLGFNSFVVINPGEAGVVSVLGKATDGALLEGFHFIPPLISKVDVYDVTVQKFEVPAQSATKDLQDLNASFAINFRLDPARVVDIRRTQGTLDNIVAKIIAPQTQEAFKTAAALRTAEQSITQRSELKRDFDTALKERLSKYDVIVLDTSVVNIRFSPDFAKAVEEKQVAEQRAQRAVYVAQEAEQEAQTDINRAQGRAEAQRLLAETLKAQGGDLVLQKEAIEAWRSGGAQMPKVLVMGSGSSRVPFIFNMSDFQEDGDRKKVTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4V1</accession>
    <name>A0A2G4F4V1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiol oxidase</fullName>
            <ecNumber evidence="1">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_003495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56802">
        <property type="protein sequence ID" value="PHX56802"/>
        <property type="gene ID" value="CP500_003495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="SSF69000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="14"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="50"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="119"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="8">
        <location>
            <begin position="550"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="802" mass="90959" checksum="0DAE427C553AC6FE" modified="2018-01-31" version="1">MTSVELEKKAMTEEEVAKLWEAFKVFDADGSGAISSEELGQVMRSLGQSPNETELRDMIKEVDVDLSGSIDFEEFKMLMVSQQGDRQSRLKLSFSVFDEDGSGQITKDEMQGVMSQFGLTEQELDEIIKEVDHDGDASIDFEEFCKLVPDESELTTGYQDSPVPIVSTQTTEISDSTAAAIASTATAINEAASATIEPNLQEATTDSDPEIARLKELLAQHPQAEQKRGTSRLQMQIGLFRLIQGAAYRCFRESFSANHQTHLRVRNLPYRIVDFVQFVRISIALYKGLGIVESACNPVLDAVVKSIEDEYARLEARIKNWKAIEKTPEMLAEQKAMLEARGKSASAKEKFAAGVEFAITIKKKSLNLRDIAEGVLAINELNRLRKMELSEEMAPPPAQSEGDPKEYLKKWNRVIVSDASEKIDGAMMPVAYWYEDFTPKLLAAFSVSTAADIPLNTVADEAALNQWYEATKTSGEFGRYGADVVESFPKCAPKQKLMLKQAWRLTHNYLNGVQKRRERMEFGRESGELSQYVSFIDVYIDRSEIKNSQMRVSFPYYIGPAVWRFFHTTAEIVSTKTPQQQTTLVAIFKDFFKLFATMYPCPYCRHHLNAYVVQNKEVEMYPVEYLVLGRDPRLNDFEVSMEAKLSTVVDGDSLRLFFWKLHNTVSSSIARSEEWYHKDEKAFYTTRYWPSIDSELARAKALKHISIATDRMYRLYGMLKPSARLTGVRATLQKLLDKRDEEGIKEACLVAQDYIKELEEAIVTGQFLQETYYFDPDLVDRAPVFSPEEEEFARSGVFVEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4V8</accession>
    <name>A0A2G4F4V8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56779">
        <property type="protein sequence ID" value="PHX56779"/>
        <property type="gene ID" value="CP500_003645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039554">
        <property type="entry name" value="HigA2-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13744">
        <property type="entry name" value="HTH_37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="38"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12256" checksum="69B73A5F859A5498" modified="2018-01-31" version="1">MTEDLENTVTTGSGNVYADLGYDNPEEMLLKAQLVRLLSQAIKAKGLNQYQAAEILGIDQPKVSALVRGQFRGYSLERLFRFLNAFDLDVEVSVKSKPENRARSYINVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F521</accession>
    <name>A0A2G4F521_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56850">
        <property type="protein sequence ID" value="PHX56850"/>
        <property type="gene ID" value="CP500_003305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="24"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="281" mass="32689" checksum="25D1E54A70DC6685" modified="2018-01-31" version="1">MSETLIDIGLPPAFPDHTQLPESDGTFVKNFQEHPQSIILTDSIGPVLQRRHPDGRYCIGQDSGIYWRETEPPEKGAEAPDWFYAPNVSARPEQGKYRRSYVLWREHMAPLIALEFASGNGNEERDATPLLMTDAGEVQKPGKFWVYEQIIRIPYYGIYEMSNDRLEVYHLRDFAYHKLEPNQRGHYPIEPLEIELGLWQGSYQNQTQLWLRWWDIHGNLLLIGDERAELEKLRTEQEHQRAEQERQRAERAEQKAARLAERLLAMGIDPDADDSPDFGHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F563</accession>
    <name>A0A2G4F563_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56627">
        <property type="protein sequence ID" value="PHX56627"/>
        <property type="gene ID" value="CP500_004235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="196" mass="19977" checksum="382AB3A78B64D938" modified="2018-01-31" version="1">MTNIEAICKGKIKMLAGYHLAGADLSGSDLADADLSQANLSGANLAGANLQRAILRANLRGADLSGADLRGADFRNADLRGAYFGNAQLSEASFGGAFLAGAAIGNVDLSGVDFRGADLRAVNFARAVLHHADLSHANLSGADLSGADLEEAILNGAVFRGANLTGANLLCAAIEQTVWDGALLDRACLQGTPLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5E1</accession>
    <name>A0A2G4F5E1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4160 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56992">
        <property type="protein sequence ID" value="PHX56992"/>
        <property type="gene ID" value="CP500_002590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025427">
        <property type="entry name" value="DUF4160"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13711">
        <property type="entry name" value="DUF4160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9547" checksum="BAA4FD75E2A4FBA8" modified="2018-01-31" version="1">MPEVARFYGIIIKIFFGDHPPPHFHAVYGEYNALIGIESLEIIEGDLPNRAEKMVIEWATLYQKELLDMWNSQEFSKLPPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5J4</accession>
    <name>A0A2G4F5J4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56995">
        <property type="protein sequence ID" value="PHX56995"/>
        <property type="gene ID" value="CP500_002605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="12089" checksum="30A7721F06CC5B3D" modified="2018-01-31" version="1">MNKQIQTIITKTQQGLKTLYGEQLDKIVLFGSQARGDATPESDIDILIVLNNSFNYSQESDKISILIADLCLEYNVLISCAFTTDEQFYHHNNAFFRNIRREGLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Q8</accession>
    <name>A0A2G4F5Q8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4331 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57079">
        <property type="protein sequence ID" value="PHX57079"/>
        <property type="gene ID" value="CP500_002025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025566">
        <property type="entry name" value="DUF4331"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14224">
        <property type="entry name" value="DUF4331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013774240" evidence="2">
        <location>
            <begin position="29"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="404" mass="42714" checksum="75CF143045EA7EC3" modified="2018-01-31" version="1">MKLTKKIRRTILAIELALIAILTPGIIAASDHDDGEVDIKGRTVNLTDLYVFREQDQNSGAADGDLVFIMNSNPRSVARYQYYFSTTALYQFHITQVGDVNSTPTGRADIIVRLAFSPPNNQGMQAAAVTVIRGGVETTTKTTVSNSLIATTPLNSNAVLNTVPVGGSNLTVFAGLREDPFFFDVEQFFRVRAGALGTGAKVGFKPASQAIDFAKGYNVNTIAVRVPKAFLQAGTGANTFDVWSTISVRDGAGGFKQFERLARPAINEGLIITPGFLEAFNNIPPRLDLSPAAAPVRQEAVATLNAVDLLDGSDNVDPNAIAGAFLPDVMRIDTTKASGYGSATNAQGSLIGGRMLLDDVVDITLGALVGSPVGDNVSYNGTPGNPGQGHKPLQPSFPYLALPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5S4</accession>
    <name>A0A2G4F5S4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Molecular chaperone DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57051">
        <property type="protein sequence ID" value="PHX57051"/>
        <property type="gene ID" value="CP500_002245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="6"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="26350" checksum="EF56419C0F9777E5" modified="2018-01-31" version="1">MSSVINHYQTLNINPTATQAEIKQAYRRLVKIFHPDSNSKTASHEEIVRLNVAYEILGDAQQRQSYDRQIAPKTPQPAQPTSNENISRQQQQTARDADEHMEQWLIKVYKPINRVLNNILKPLKKEIDELSADPFDDELLEKFQTYIETSRDFLKKAQNVLRSMPNPSNVAGVAAYLYHCINQVGDGIEELHLFTLNYDDRHLHTGQELFRIASRLRREAQAELKIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5U0</accession>
    <name>A0A2G4F5U0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)H-quinone oxidoreductase chain 4</fullName>
            <ecNumber evidence="7">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(P)H dehydrogenase I, chain 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">NDH-1, chain 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ndhD</name>
        <name evidence="9" type="ORF">CP500_001575</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cellular thylakoid membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57118">
        <property type="protein sequence ID" value="PHX57118"/>
        <property type="gene ID" value="CP500_001575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00491">
        <property type="entry name" value="NDH1_NuoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022997">
        <property type="entry name" value="NADH_Q_OxRdtase_chain4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="3 7" id="KW-0874">Quinone</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="492"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="8">
        <location>
            <begin position="133"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="576" mass="62888" checksum="2DA5583BC2915DB6" modified="2018-01-31" version="1">MIADQFPWLTAIVLLPLVASIAIPFLPDTDGKTIRWYALGVGLADFVLMCWVFWTHYDPTISTFQIVEKYSWIPSLGLNWSVSVDGLSVPLVLLAGLVTTLSIFAAWEVDRKPRLFYFLMLVMYSAQIGVFVAQDIMLLFIVWELELIPVYLLISIWGGQNRRYAATKFLIYTAGASIFILIAALAMAFYGGGSPTFDILELGLKDYPLGLELLLYAGLLIAFGVKLAIFPFHTWLPDAHGEASSPVSMILAGVLLKMGGYGLIRLNLELLPKAHVYFAPIMMVLGVVNIIYGALNSFGQKNMKRRLANSSISHMGFVLLGIASFTDLGINGALLQMISHGLIASVLFFLAGVTYDRTHTMIMDEMGEIGKVMPKVFALFTVGALASLALPGMSGFASELSVFVGVATSDIYSDSFRAVIVFLAAVGVILTPIYLLSMLRQLFYNSGAAAACDIEDLDLQNQRNNLDEAVCFGNSCVLPGDAPFIDAQPREVAIAFCFLIPIVGIGFYPKMAMQVYDTKTVAVNAEVRQSYIQIAQDNPRIYANQLLIPKIARVQRAPTLGEITGSESASVLGIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5V1</accession>
    <name>A0A2G4F5V1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsK</name>
        <name evidence="7" type="synonym">rps11</name>
        <name evidence="10" type="ORF">CP500_001700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57136">
        <property type="protein sequence ID" value="PHX57136"/>
        <property type="gene ID" value="CP500_001700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="14017" checksum="A42D8191852D66C3" modified="2018-01-31" version="1">MARQQTSKKSGAKKQKRNVPNGVGYIQSTFNNTIVTITDLNGEVISWASAGSSGFKGAKKGTPFAAQTAAESAARRANDQGMRQIEVMVSGPGAGRETAIRALQGAGLEITLIRDVTPIPHNGCRPPKRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5V7</accession>
    <name>A0A2G4F5V7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57129">
        <property type="protein sequence ID" value="PHX57129"/>
        <property type="gene ID" value="CP500_001650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="12505" checksum="350B6665876832C9" modified="2018-01-31" version="1">MNIQNRQKLSEIIKTARGTMSQRAFGKLLGVSATAVQLWERGDTVPDTENLGKLAARAGYTLEEFLSFLDGNPVSHPPEINDIVKKIQFLPPRQVALIARAVADRFAASAEAAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F606</accession>
    <name>A0A2G4F606_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type II toxin-antitoxin system HicA family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_001395</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HicA mRNA interferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57223">
        <property type="protein sequence ID" value="PHX57223"/>
        <property type="gene ID" value="CP500_001395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038570">
        <property type="entry name" value="HicA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8140" checksum="5F00AED0742EBFBC" modified="2018-01-31" version="1">MPKKIRELKSLLLKAGFVCQPAKGSHSKWKHPKLAKAIIIAGKDGNDAKLYLEKSVNETLEALRQIEAEETEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F610</accession>
    <name>A0A2G4F610_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_001300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57188">
        <property type="protein sequence ID" value="PHX57188"/>
        <property type="gene ID" value="CP500_001300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="116"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="345" mass="38626" checksum="346CD15D94983A27" modified="2018-01-31" version="1">MTIKLNQNLRIFSFIFGGETFIYVFKRLLQALLTLFLASILCFAIIELAPGNYLDTLSQNPKISPETLKQLEQQFGLDKPAFVQYWLWLQQIVTRGNFGTSFVYQRSVASLLWERVPATLLMAIASLIVTWAIAIPLGIIAAVNQNRTADRILQVVSYTGQGFPSFIMALLLLFFAQNTSPLFPVGGMTSIDHADLPWWGQIMDYGWHLILPTVALSLTGFAGLQRLMRGQLLDVLRQDYIRTARAKGLPENRVIYIHALRNAVNPLITLLGFEFASLLSGAFIAELFFNWPGLGKLTLDAVNNQDLYLVMATLMMGSAMLIIGNLLADLLLKAIDPRIKLEDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F650</accession>
    <name>A0A2G4F650_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit alpha</fullName>
            <shortName evidence="11">RNAP subunit alpha</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">RNA polymerase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Transcriptase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoA</name>
        <name evidence="13" type="ORF">CP500_001695</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase alpha chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57171">
        <property type="protein sequence ID" value="PHX57171"/>
        <property type="gene ID" value="CP500_001695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00059">
        <property type="entry name" value="RNApol_bact_RpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02027">
        <property type="entry name" value="rpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RPOLD" evidence="12">
        <location>
            <begin position="27"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha N-terminal domain (alpha-NTD)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha C-terminal domain (alpha-CTD)" evidence="11">
        <location>
            <begin position="247"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX57171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="321" mass="35654" checksum="709B8E1D51D97983" modified="2018-01-31" version="1">MEKGGHSVAQFQIECIESNTDKDRSQYGKFVLEPLDRGQGTTVGNALRRVLLSNLEGTAVTSVRIAGVNHEFATIEGVREDVLEILLNMKEVVLKTHSQQPQIGRLRIEGPVTVTADRFDVPSEVEIIDRSQYIATLSPGSVLEMEFRIEKGIGYRAVDRSRDDGAALDFLSIDAIFMPIRRVNYSVEDARVGGTVEKDRLIMEIWTDGSVTPQEALSQSAHILVDLFAPLKDITQDSLKPESQGVTDPTSQIPIEELQLSVRAYNCLKRAQINSVADLLDYTQEDLLEIKNFGQKSAEEVIEALQKRLGITLPQEKSSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F667</accession>
    <name>A0A2G4F667_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4342 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57215">
        <property type="protein sequence ID" value="PHX57215"/>
        <property type="gene ID" value="CP500_001475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025642">
        <property type="entry name" value="DUF4342"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14242">
        <property type="entry name" value="DUF4342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4342" evidence="2">
        <location>
            <begin position="50"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="14104" checksum="12301171BF4B1776" modified="2018-01-31" version="1">MEIPTEREEGRVGERELESIPVGAKVSAEKVSGVELESNPLETPIYTQEKVSVEELKINGDDLVAKVKELIHEGSIRRIIIKNEEGQILIEVPLTVGVVGGVIGATLFPVIAAVGAIGALVAHMTIIIEKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6L5</accession>
    <name>A0A2G4F6L5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57396">
        <property type="protein sequence ID" value="PHX57396"/>
        <property type="gene ID" value="CP500_000190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="104"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_MalT" evidence="3">
        <location>
            <begin position="626"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="650"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="782" mass="89869" checksum="F45CE1F207DBFF37" modified="2018-01-31" version="1">MVDSLKASEDGLKIVDEARRRKRWQKNSLTWVQEAKTSEATLKRFWARKFFIDRFAFIAICKAVGVNWEEIAEPSEIQETELPVVSTVKAHPSIPNQNFVGRDKAIASLNTHINQGAKIIVIQAPGGVGKTTLAHEYLNSQGFDLVLDLPMAKEKDNIQLVDSVIEGWLKQDFEEEPGREFWEMLRRLKRQLQTRKIGILIDNLEPALDGQGRFIEPHRRYVELLRVLADPTVQSVTLITSRVRLCEPDVNVAHYLLPGLNEPAWQQFFMSRHINIDIPTLNAMNKAYGGNAKAMGILCGAILEDFDGDMVAYWRNNSGDLLVKADLENLVTSQFQRLQELNSEAYRLLYRLGCYRYQDVPTVPTEGLLCLLWDVPEGQRRRVIESLRNRSLVEFNNGEYWLHPMIRAEAIARLRASEDWEEANRKAAEFWTDSVKTVETVENLLKAFEAYYHYVQINDFEQAGSVIVRRRDGSSWRNGESLGRSFYRLGLLQPMIYSINSIINQVKTDYILSILYNILGVFYWLSGGINAAIECHNLSFKAAERTLSSINLSPSIDFYAKRRKTWSLFNTGLCKIDLWELEKAVIFFQDIEFICNSKNSETGLYENEKDYLYCLAFLNSCLRFKETAMSYAQQGEVVIHKIDSSYWSQGYSLLFMGLTYKNLGEFDKSFEMFRQAIAFAEKTHYTQVKAKALTGLAELYREQSDFTTARFHHSESIALLEKIGAKCDLAEAHYQFALTHQKMGDAEKSQTPFQEAIRLFTEMEAPKQVEKVRKAIGKIDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6T1</accession>
    <name>A0A2G4F6T1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57217">
        <property type="protein sequence ID" value="PHX57217"/>
        <property type="gene ID" value="CP500_001235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12553" checksum="8A3E8825C5C1CC4F" modified="2018-01-31" version="1">MVQNVSPIALLNKINPKRTMTKTEILAALKNLTPEERLEIIETASRMMREEIEEKVQRKAERKRRLRAAAEAAVNDYMPGGALYDLWSPDSEPYFESEEEYLNAGVKANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUI1</accession>
    <name>A0A2G4EUI1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000245">
        <property type="protein sequence ID" value="PHX53199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53199">
        <property type="protein sequence ID" value="PHX53199"/>
        <property type="gene ID" value="CP500_022760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="686" mass="76113" checksum="A3CD2CB3C5F217B0" modified="2018-01-31" version="1">MSQDRKTPGHLSESESLEPNKDTSSLVPLPARKNRAQRLKELRSMLISGEMPGENLALAPSSSGENLQPPSEHNRVWLSWLNKWQFWLLVSLMLSVGMGFVAILSLLNLTSQSNCSKIFWPTASANDRFFCAQEAASKRTADDLLRAIELVNALPQDHPMRPRINGQIELWVQDMLRLGNSSFQEGKLQEAIAIARKVPQNVPAYPMVEKQIEKWQSSWKDAEKIYGTAENHLRKEEWVLAFREASLLLDTGNTFWESTKYEELTKAIQATKAEGNKLIKARNKAEEGGVDNLVTGIKLAQGIDQKSYLYQAANKLIGELSNKILDIAQKRLESGDWQQAIAIANKIPDGGNLQEQVKDFNDLANAIGQASTGQIDGLSKAIAIAQKLNSNRPFYKKSQDLITRWQQEIADVKTLDLAGKLAAPGGVKNLRAAIAQLQTVPESNPRSTEARSQISRFSRQIEQIEDSPFLQKANDLANTGDPNALEAAVDQARRIGQGRVLYGEAQTKIQAWIERRQRLQDQPFLDKAQQLAASGNLPEAIEMARRIRPGRVLYEQARSSIRTWDVQSQSEQGLQSARQVAQAGTVDALETAISLANQVPDSSSLRSQASQAIEEWSQRILAIGMEESSSDLAGAIAILKKIPAGTRSFQEARSQIQVWQQSLNSPAAESEPPVPPETEPYRPPNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUI7</accession>
    <name>A0A2G4EUI7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_022700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000241">
        <property type="protein sequence ID" value="PHX53212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006631392.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000241.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53212">
        <property type="protein sequence ID" value="PHX53212"/>
        <property type="gene ID" value="CP500_022700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="17"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="120" mass="13358" checksum="C378E7A01F5B7E50" modified="2018-01-31" version="1">MIHIDQKTHTLQDGTTVIVLAPTGRLDITTAWQFRLKLQECISKLSRHVVVNLGQVNFIDSSGLTSLVAGMRDADKVKGSFRICNVHPEAKLVFEVTMMDSVFEIFETEEEALEGVPRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV21</accession>
    <name>A0A2G4EV21_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000224">
        <property type="protein sequence ID" value="PHX53280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53280">
        <property type="protein sequence ID" value="PHX53280"/>
        <property type="gene ID" value="CP500_022360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="67"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="182"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="360" mass="40247" checksum="200C137F4EB9E1DA" modified="2018-01-31" version="1">MSNFPSNLLINLSFLISKPTGLSIYAKNLFPHLKSLSPTLLSAAEIPNYTCYQIPSNLTPEQGTKGHINRLLWTQTQLPKIYKELKSNLIFSPIPEAPVFAGCRYIITVHDLIALRFPRRFDPLTPYHRYYIPQVLRQAEHVICDSEATAKDIADFCQIPTDSITSISPGYDTSFFRFLDLPTSNYFLYLGRHNPHKNLHRVVAAFAALPSSCEYELWIAGSEDKRYTPLLKVQVAEWGLLDRIKFLDYIPVGDLPKVINQAIALVFPSLWEGFGLPVLEAMACGTPVITSNLSSMLEVGGDGALLVNPYSVAEITAAMQQVAGDSQVRSHLRALGLARAKQFSWEKTGRETAAILDRYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV41</accession>
    <name>A0A2G4EV41_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DUF1232 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_021735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000203">
        <property type="protein sequence ID" value="PHX53395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53395">
        <property type="protein sequence ID" value="PHX53395"/>
        <property type="gene ID" value="CP500_021735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010652">
        <property type="entry name" value="DUF1232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06803">
        <property type="entry name" value="DUF1232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1232" evidence="7">
        <location>
            <begin position="23"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="104" mass="11642" checksum="FAA4424BDEA21546" modified="2018-01-31" version="1">MSFSIQSLYNWYRDTIRNPKYRWWIILGTMAYLVSPIDIAPDFLPVIGQIDDVAIAVLLISEISQMSIDYFKSRQTQTNSTSEATSGTSEAKASTVDVDAVSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV70</accession>
    <name>A0A2G4EV70_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4115 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53330">
        <property type="protein sequence ID" value="PHX53330"/>
        <property type="gene ID" value="CP500_022010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025194">
        <property type="entry name" value="DUF4115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13464">
        <property type="entry name" value="DUF4115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4115" evidence="1">
        <location>
            <begin position="207"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="293" mass="32951" checksum="02EDBF5C4ED116B1" modified="2018-01-31" version="1">MTKNLFFLLFKTTKKKQHSQEAERSQKLAEIGVKLRDFREKESICLEKVAVVTMIRREILQAIEEGQLDQLPEPVYTQGLIKRYAEAMGLDGAEFADFFPIEQAAPRSTPKISWQDLPQLRPMHLYLFYTFLIIFSVNSLSQLMGGSLTAKSDTRTEQLALQQQEIARLAAEFDRAPAKQKVDIYKPLEAARSNKSLEKPGNKPVMVSVTFKEESWLQIEIDGKMEFEGVLPSGTQRTWQAKEKLVVVAGNAGGVLIAFNNGQAEQLGDPGVVKEVVFKADELNLSEKTKNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV74</accession>
    <name>A0A2G4EV74_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">2-octaprenyl-6-methoxyphenyl hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_021855</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000208">
        <property type="protein sequence ID" value="PHX53366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53366">
        <property type="protein sequence ID" value="PHX53366"/>
        <property type="gene ID" value="CP500_021855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="7">
        <location>
            <begin position="20"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="422" mass="46609" checksum="6E04021BE2A116C7" modified="2018-01-31" version="1">MPVNQLSATTVPLQTTEFDFDIAIVGGGIVGATLACALKDSGLKIAIIETQLPAAAAAKKQAYAVTLLSGMILESIGVWEQILPQITTFEQISLCDGDYPGVVEFHRPDLGNTGKLPVPKSALGYVGEHRVMLSALHECLAKNPNFSWVCPAEVIEVKYLTNCAEIAIKQNGETRTIRSRLLVAADGSRSRIRTAANISTRGWKYWQSCIAITIKAEKPHNDIAFERFWPSGPMGVLPLPGNRCQVVWTAPHAEAKALQKLDETEFLALLEQRTGGLLGRLELESDRFLFPVQLMQSDRYVLPRLALIGDAAHCCHPVGGQGLNMGIRDAGAIAQILQQAHQKSEDIGDLKVLKRYHNWRKKENLIVLGFTDFLDRLFSNTWLPIVAFRRFGLWCLRTIGPVRLLALRLMTGLMGRPPELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV99</accession>
    <name>A0A2G4EV99_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease P protein component</fullName>
            <shortName evidence="6">RNase P protein</shortName>
            <shortName evidence="6">RNaseP protein</shortName>
            <ecNumber evidence="6">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Protein C5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnpA</name>
        <name evidence="7" type="ORF">CP500_021370</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RnpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000194">
        <property type="protein sequence ID" value="PHX53459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53459">
        <property type="protein sequence ID" value="PHX53459"/>
        <property type="gene ID" value="CP500_021370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00227">
        <property type="entry name" value="RNase_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020539">
        <property type="entry name" value="RNase_P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00648">
        <property type="entry name" value="RIBONUCLEASE_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="15329" checksum="5431516D4BA5BA6B" modified="2018-01-31" version="1">MLPETNRLKHRKDFSAVYRKGMRRNSAHLSLRALRKPKSVTLAQPTAEKSLQPTRTGISISLKVSKRAVVRNRIKRQIRAALRHLLPRLKFGWDLVIVVRPIAQECNYAEILQELEQLLVEAEVLDGNSRGSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVC7</accession>
    <name>A0A2G4EVC7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_023165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000271">
        <property type="protein sequence ID" value="PHX53127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53127">
        <property type="protein sequence ID" value="PHX53127"/>
        <property type="gene ID" value="CP500_023165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="21"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="13027" checksum="5457AADAD17BE44D" modified="2018-01-31" version="1">MSQIFGQITVEELSQRLAEPTTDKLQLVDVREPHEVEVASLPGFAVFSLSEFAEWSTEIADRLDRDTETLVLCHHGMRSAQMCHWLTDQGFTNVKNIIGGIDAYSMVVDRTVPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVM6</accession>
    <name>A0A2G4EVM6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_022665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000239">
        <property type="protein sequence ID" value="PHX53217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53217">
        <property type="protein sequence ID" value="PHX53217"/>
        <property type="gene ID" value="CP500_022665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="392"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1018" mass="113475" checksum="632EA8BC4DDAB856" modified="2018-01-31" version="1">MDNFQISGSGGVRQGMLRSLNLRSEELERTVLMFLVYTLTSVGLIWLELSTVGLFLDEFGADKMPWIYIASAFIGSGLGFVYSWMQKILPLRRVIVVVLAMMSVPLFLFRFGIGYEDTKIAGISIAFITIFLMWLWVEACYVLNDLNTSITSNQLFNIREIKRTYPLVSSGYLVAGVVSGFSLPVLLHVVGLKNVTLVSGLMVATGSILLYYLTEKYRQAFPETAHWSDDDDEDDDNQEFTARKVTGPLQKYAVPLVSFFVLAEVLYVLIDFQFYSQLEYKNAEEGVSVASKIASFLGIYEGIQGLFQVGTQWFASSRLVERIGVFVTAMILPAGIAILGVLTLGSSLGQLVPVFIGLVLLRFLDELLHYTLLETVSPVLFQPIPDNIRSGIQTLVNGVGEPLSCGVTGVGILILLWITKYILPHQSENQFHDRQSLVFIAVIVLLSLVWLFVVWLIRSQYVGLLVKSAERGRLGVTDVDLKALKRAVVETLEQPGGEDDKRSCIELLTQIDPKNVGEVLAPILESLPPALQRQSLETMLQHPNPAYLEAVRHLSEQELPPEVLALALRYVWLTDAEPNIESLRSYLQPTVDAVVRGTAAALIMRRGDRQQKAEATNTLRQMLTHKQERERVMGTRALGEADYLQGLRLYIPNLLQDESLRVRCALLDVISATHLEEYYPSLIRGLGYKSTRESALGAIVKLHNDAIPLLVHLAEDIHKSDLVRLQAWTALGQIGSVEAIDILVSNLLTSWGTTRRNILRILLKMPSEAGIEGVLDRIGRSGLETLIEQELMFIGQIYAGMVDLSSVTTYGNFPTEDPNSDDEPAADATQLLRRALAGLESDATDRCFLLMKFLYPLDTVQAAAFNIASGQPSLIARGLEILDNTVDIANKRSLINLLDHHSEREKLSNLSELMVYKPLAPSDRLRRLLELRHFLSDWALACCFHLAREARWTLTAQQTLVCLRHPTGFVREAVLAYLKIASPKALLELLPRLQNDPDRLVSGQVERMMAELGAGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVW0</accession>
    <name>A0A2G4EVW0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_020235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000164">
        <property type="protein sequence ID" value="PHX53671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53671">
        <property type="protein sequence ID" value="PHX53671"/>
        <property type="gene ID" value="CP500_020235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="22330" checksum="B3AD233D20358C72" modified="2018-01-31" version="1">MQNTTLPENNSSSNSNNYSPSVPISLYREVTAELQSAQAMLDSLKTHNQQLLQQNQELRREVETVVQASVYLQQAVNSAQSVTQTGMPQMPPVNRFNLSAASPRLASLPLQANHPVPEEPSPVAQTVAFPFSIAEPELTAPLIPEKLPEKLFTEIPETPYRLRTKPKKASDLSGLWLAIAIFLIVIAAFGGGYLVVRPLLMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWB1</accession>
    <name>A0A2G4EWB1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribonuclease E/G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_019275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000149">
        <property type="protein sequence ID" value="PHX53842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53842">
        <property type="protein sequence ID" value="PHX53842"/>
        <property type="gene ID" value="CP500_019275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00757">
        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="35"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="444"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="690"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="690"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="741"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="760" mass="84592" checksum="AB8A56833D2507E4" modified="2018-01-31" version="1">MTKQIVIAEQHRIAAVFSEDQIQELVVATGSHQVSDIYLGIVENVLPGIDAAFVNIGDPERNGFMHVTDLGPLRLKRSAGAITELLTPQQKVLVQVMKEPTGSKGPRLTGNITLPGRYLVLMPYGRGVNLSRRIKSEAERNRLRALAILVKPAGMGLLVRTEAESQTEEAIMEDLEVLQKQWESVQIEGGTTRAPALLNRDDDFIQRVLRDMFSGDVNRIVVDSQNGIKRVKQQLMSWNGGKLPAGVLIDHHQERAPILEFFRVNAAIREALRPRVDLPSGGYVIIEPTEALTVIDVNSGSFTRSATARETVLWTNCEAATEIARQLRLRNIAGVIIVDFIDMESRRDQLQVLEHFNKALRSDKARPQIAQLSELGLVELTRKRQGQNIYELFGHTCPTCNGLGHLVQLPGEEEIAPAVRESGDRTSATSNRVLLNLPEGLERRTLAPVATATSSPAREERSPEPQRAPWEPQNESLDFETGGNASPLDLLNHPSYQDLGNGTRRRRRRRIGEEAFGVSVEEEPVRSKLRLPNTSIAPVAEPRAEYLPPPGIRAASEGFGLVNMATVGRREDFERVRPTKSELMKPMVEPPEVISVEMTAEEQDVYAVMGVSPLVLINRSLKNPKNAIVSVTMPGETPTKPPFEQLELEFEPVASPEDEDGSEQDYYAEMSVVEPVFSPIFSEDAETEIYDESPIDDIDDFDPISEMSEMSEEAIELIQSDESIQPDESIQSDESIQSEEPEEPATNRRRRRRSSALLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWE0</accession>
    <name>A0A2G4EWE0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_019175</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000146">
        <property type="protein sequence ID" value="PHX53872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53872">
        <property type="protein sequence ID" value="PHX53872"/>
        <property type="gene ID" value="CP500_019175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="23"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="335"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="373"/>
            <end position="380"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="582" mass="63905" checksum="C09ACB015B56EF1D" modified="2018-01-31" version="1">MARYSRLQKLGAYMRPHWKQASWGVLSLLIVNAVGVYIPLLIRNAVDTLQVALKFDQVFSYVMLILVLASIMWVIRMVSRILLFGVGRLVEFDLKQQIFNHLLTLEPSYFAANTVGDLINRATSDLDNIRRLLGFAVLSLANTAFAYALSLPVMLGINVRLTLLAIAVYPLMLVLVQLFSDKLRIQQLTVQEELSAMSDLIQEDMSGISVIKIYAQEENERRAFADCNKKLLNANLTLAKTRNFIFPLLGGLASLSLLVLLAAGGGSIAKGEISVGDFVALLIYVERLVFPTALLGFTITAYQRGEVSVDRIEAILTVEPKIYDKGDALEIPTPVRGEIVARNLNYNYPGAKTPALHNVNFTIKPGETVAIVGAIGSGKSTLANALPRLLDIDAGELFVDGLDITQVKLTDLRGAIAYVPQESFLFGTTIKNNIRYGNPLAEQPEIEAAGKQAQIHAEILNFPDQYKTVVGERGITLSGGQRQRTALARALLVDAPVLILDDALSSVDNQTASDILKNLATGTDRKTVIFISHQMSAAAGADRIFVMEKGEIVQTGTHRELVGQTGLYQYLWNQQQLEELLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWH7</accession>
    <name>A0A2G4EWH7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_019540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53816">
        <property type="protein sequence ID" value="PHX53816"/>
        <property type="gene ID" value="CP500_019540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041518">
        <property type="entry name" value="Bac_GH3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18034">
        <property type="entry name" value="Bac_GH3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="3">
        <location>
            <begin position="9"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_GH3_C" evidence="4">
        <location>
            <begin position="401"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="542" mass="58328" checksum="77ACC29CE68CAFE9" modified="2018-01-31" version="1">MIDNLSLPELVAQMFVVRASGYLFDHQIRYPEWEPTAEKLRHYLENLGVGGVILAGGSAAELTMRSHQLQSWAKFPLLLAADIEEGVGQRFAGATWFGPPMAIAEIAKKNPEAADRYAEQMGAVTAMEARAIGLNWVLAPVVDVNNNPDNPVINVRAFGETPEIVSTLASAFIRGASTQSVLTTAKHFPGHGDTAVDSHLELPILPHSPTRLAEVELPSFVEAIANGVDAVMTAHLLIPAWDEEFPATLSRKILIGKLREELGFQGLIVTDALVMGAIANKYGANKGAVLAAEAGADVLLMPLDPEEAIRAVCEAVTQGRISITQIKDSVKRIWEAKQKVGLSISDSKETGHNSVVSLQGGSQNPALIELSLLSTPEAMTTAANILRDSLKFGGNLPLPQPQKNQLLRNLIVVDDVLGCEFLGNHTPAIALPAQLGYELQLIDDRAGAIGDTANTDSFCPTLLQVFIRGNCFRGSAGLTEAAQNWFQKLLTTGELQAVLIYGSPYVLEQFLPYLPPSIPYIFCFGQMPAAQTIALELLFGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWL3</accession>
    <name>A0A2G4EWL3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53923">
        <property type="protein sequence ID" value="PHX53923"/>
        <property type="gene ID" value="CP500_018875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15917" checksum="0A06F0CA9A3CD55D" modified="2018-01-31" version="1">MPAKDIYHNCVKNALVKDNWTITHDPLSLKWGTKDMYVDLGVQKLIAADKAQRKIAVEIKSFVGASEMNELEKAIGQYIVYHDVLAEIQPDRELYVAVHDEIYEGLFEEPIGQLLLRNNRVKLIVFQPQKEVILRWIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWM7</accession>
    <name>A0A2G4EWM7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000150">
        <property type="protein sequence ID" value="PHX53840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53840">
        <property type="protein sequence ID" value="PHX53840"/>
        <property type="gene ID" value="CP500_019380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045830">
        <property type="entry name" value="AraR_wHTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19368">
        <property type="entry name" value="AraR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="249" mass="28448" checksum="42AF33DCF68CDCE0" modified="2018-01-31" version="1">MARGTKKSEGCSLADFKVGVDNVIFSVDTVQNRLLVLLIMRHDEPFIDFWSLPGTLVRHGESLENAAYRILSEKIRVKNLYLEQLYTFGEPGRDPREFTRGDRYLSVSYFALVRFEEAELIAGNIAADASHRLSGIAWYPVEQVPKLAFDHNQILEYGYRRLRNKLEYSPVAFEVLPELFTLSDLYQLYTTILGESFSDYSNFRTRLLKLGFLCDTGVKASRGAGRPASLYRFDATAFAPFKDKPLVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWU4</accession>
    <name>A0A2G4EWU4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PIN_10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54004">
        <property type="protein sequence ID" value="PHX54004"/>
        <property type="gene ID" value="CP500_018365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041375">
        <property type="entry name" value="VapC45_PIN-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18478">
        <property type="entry name" value="PIN_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN_10" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="11839" checksum="5E138DDA0FAB3384" modified="2018-01-31" version="1">MRLLLDECVPRPLKRELTDYEVRTVVEMGWAGKKNGELLKLMMQESFTILLTTDQNLRYQQNLQQAGVAVIVMVAPSNRLPDLLPLISSVCSVLTRITPGEVIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWU6</accession>
    <name>A0A2G4EWU6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000169">
        <property type="protein sequence ID" value="PHX53637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53637">
        <property type="protein sequence ID" value="PHX53637"/>
        <property type="gene ID" value="CP500_020455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="651"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="680"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="713" mass="80881" checksum="B19F839C3DBD4D0F" modified="2018-01-31" version="1">MQEILYLEVPTPDTAAVCAWLQQEFEPAIGQKVITPDGFRLVSSTTAVGAIASGAQIANSKSTVPTSNSVSQNHQSTELSIFVWAVQRTTYLKVFRLENAPPGERKFLESLNLAVRNKFPELYPQPPVIDLSKQSIFEALAPYYPLTVKYFQKMPKGEYDLQRVYWWEQRWREGTRNPQQPKQVVFLKKKKGSSATDSVTNLTDVTDYDLIYIGGALGVIHAAVMARLGYRVLLVERMPFGRMNREWNISRDEIQSLIDLDLFTAVEVETLIAREYKDGYNKFFDSNNPSFAKAPVLHTPKVLNIALDGEKLLYLAGVKLTEAGGEIWDETEFIRADIEEEKVVLQCRDLSKKCDRTVSGRLLVDSMGSASPIAWQLNEGRAFDSVCPTVGATIDGGFDPEVWDSEYGDVLYTHGDISRGRQLIWELFPAAGREFTVYLFHYHQVNAENPGSLLELYEDFFTILPEYRRCDLDKLVWKKPTFGYIPGHFSTGSRDRAVAFDRLIAIGDAASLQSPLVFTGFGSLIRNLFRLTNLLDTALKHNLLSANHLNQIRAYQSNVSVTWLFSKGMMVPTGRSLPPQRINSILNTFFGILTEEKLTVTETFIKDRTDWLTFNHLALKAARKNPLLLVWILDFVSFGDVWRWLGSYFSFTLLALASWLFGWLPNFARRLQPWLEPRYPALWLWLLATSYALTYGMGRGATVLSSNPKPNTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWX6</accession>
    <name>A0A2G4EWX6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NAD(P)H-quinone oxidoreductase subunit F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_020285</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000165">
        <property type="protein sequence ID" value="PHX53667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53667">
        <property type="protein sequence ID" value="PHX53667"/>
        <property type="gene ID" value="CP500_020285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010217">
        <property type="entry name" value="NU5C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01960">
        <property type="entry name" value="ndhF3_CO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0874">Quinone</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="604"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="9">
        <location>
            <begin position="73"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="8">
        <location>
            <begin position="139"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="624" mass="67851" checksum="55B1B8FCB79EB8EC" modified="2018-01-31" version="1">MNQFLLQSCWWIPLYGLIGAILTLPWSTGTIRKTGPRPAAYFNLLMTVLAFVHGSVIFRETWNQPPQQLLLDWVQATDLNLSFAIEISTVSAGAMELVAFLSLLAQIYALGYMEKDWAMARFFGLIGFFEAAISGIAISDSLLLTYALLEMLTLSTYLLVGFWYAQPLVVTAARDAFLTKRVGDVPLLMGVVTLSTLAGSLNFSDLETWAETATLSPLVANLLGLALIAAPTAKCAQFPFHLWLDEAMEGPNPASIMRNTVVVGAGAYVLIKLQPVLALSSVTDEVLVVLGAVTAVGASLVAIAQIDLKRTLSHSTSASMGLVFIAVGLNQVDIALLLLFAHSISKALLFMSAGSIISTTNTQNLTEMGGLWSRMPATTTAFLVGSAGMVALLPLGNFWVMRRWLNGFWTVPLWLVVVLLLVNSLTALNLTRVFGLVFAGKPQPKTRRTPEVGWLMALPMVILTVTGLLVPWMLQQWQLLISWHGPWSETGDFDTLNLLLKTLGTPLLMLSGLIGCGIGVAIYWYGVLPRPVRLPIPVLQDLLAYDFYIDRVYLLTVVWAVDSISKISAWTDKYVVDGAVNLFGFATIFSGEGLKYSGTGQSQFYVLTIAGGVAVLLGLVIWQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWY0</accession>
    <name>A0A2G4EWY0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">accB</name>
        <name evidence="4" type="ORF">CP500_018335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54031">
        <property type="protein sequence ID" value="PHX54031"/>
        <property type="gene ID" value="CP500_018335"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00531">
        <property type="entry name" value="BCCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="3">
        <location>
            <begin position="105"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="184" mass="19392" checksum="904903B2937FDEC5" modified="2018-01-31" version="1">MQLDLNQLCELLTVLDKTGISELTLKSGELELTIRKGIQASEPGTLAVGHPAVTTLPTIAETFASPTLASPSTVSQNSGASLTDSAPLAPAVVPAPVPAPVDTKWVSIISPMVGTFYRAAAPDEPPFVAVGDRIKVSQTVCIIEAMKLMNEIDADEVSGQVMEILVQNGEPVEYGQILMRINPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX62</accession>
    <name>A0A2G4EX62_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000121">
        <property type="protein sequence ID" value="PHX54135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54135">
        <property type="protein sequence ID" value="PHX54135"/>
        <property type="gene ID" value="CP500_017705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7086" checksum="767583C9110C730B" modified="2018-01-31" version="1" fragment="single">SLLPPHSVYVPVGGAECGLQRQPEPQVRESPAAPASPRGTINAIILTLILKRLDTTPQETTDAWVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX79</accession>
    <name>A0A2G4EX79_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system VapC family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000121">
        <property type="protein sequence ID" value="PHX54143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54143">
        <property type="protein sequence ID" value="PHX54143"/>
        <property type="gene ID" value="CP500_017745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09872">
        <property type="entry name" value="PIN_Sll0205-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041705">
        <property type="entry name" value="PIN_Sll0205"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="128" mass="14606" checksum="119B140D4AB05E89" modified="2018-01-31" version="1">MKLLLDTHTFIWWDSSPQKLSSKALAFCQNPENTLLLSMASIWEIQIKLQLGKLSLNLPLPELIENQQQTNNIELLPINLTHVLTLDTLPNYHKDPFDRLLICQAIVEDAVLLSGDSTLANYPVKLEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXE1</accession>
    <name>A0A2G4EXE1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54191">
        <property type="protein sequence ID" value="PHX54191"/>
        <property type="gene ID" value="CP500_017420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="6621" checksum="8419BED3400690C1" modified="2018-01-31" version="1">MVGGKLIMGLFWAIALKNATLQLAIPSNSQGYRNQSSWVWIKINRVVFAMLVTSAITAHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXH1</accession>
    <name>A0A2G4EXH1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54233">
        <property type="protein sequence ID" value="PHX54233"/>
        <property type="gene ID" value="CP500_017365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="125"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="441" mass="48670" checksum="4F4D2451FFA94D1C" modified="2018-01-31" version="1">MSEADLQANQQQPHSILHSDMESLRSDFAGDGGYAPIDPHSTDTAAAVRQTPEEDWQTVDFPNAISVDAIPTKPETKNLPSHAQVTPADSPPISDNLKNLLANSEQAKGKGSTSVTLMQALHECNRDLLGRISQLETALQESQTNLRVRETLLEQRNAELQNAQEQLTRLFGKQEVSNQTLQSQEILVESLTQQLATTQTRLAMVERESAATVQRYNEQLHQLVTTENVCRELRSRLHRQQRHTLQFKAALEKSLEMPQKSIANIEKVENTDDRASAQLESLLAAVKAQSVPLPATFNASPVQPWSDLSEPHPEVATSKEAIGAESLVSQEFNTLAQASGIELHENENFSQIESSPRIAEAQQLVAEPETESATAKYSSPELIGAAKILSSVETFGIQEVRSNPVQPTAFAEPQWLISMISPLRAAKKRRSLAEIELPSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXH9</accession>
    <name>A0A2G4EXH9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54150">
        <property type="protein sequence ID" value="PHX54150"/>
        <property type="gene ID" value="CP500_017645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="16486" checksum="12468F6820BECE7B" modified="2018-01-31" version="1">MPPKTVSLSKKCILDTDHVSLILQKSPQVIANAAKHEISVTIVTVQELFNGWVGRINDPSLVHNLPGLYSKLSTTVQYLKTIEVLDFTAEADTCLKKLLKDHPPLRKNRLQKDMRIAAIALSVGATVITRNQRDFCQVPGLSIEDWTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXK4</accession>
    <name>A0A2G4EXK4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Poly-gamma-glutamate biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_019085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000144">
        <property type="protein sequence ID" value="PHX53887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53887">
        <property type="protein sequence ID" value="PHX53887"/>
        <property type="gene ID" value="CP500_019085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07381">
        <property type="entry name" value="MPP_CapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019079">
        <property type="entry name" value="Capsule_synth_CapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09587">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00854">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="PGA_cap" evidence="4">
        <location>
            <begin position="247"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="565" mass="60992" checksum="D15CF761F300D424" modified="2018-01-31" version="1">MSQQDIVNLAKEGDAKAIAFLIGQALQSFGVTAKASSENDTLHLLLEGEQLPAQDACIRVAVKGLQRLQPNHLYSLTIYGRQKGQQLPAWTQNVELTKTLTSQPASTGAARITAVLQKVEQHQNVKVAETKITEKNPPKIPTITTEKPNNQPQEPKLVSHKTKNTKPWLSVAVLSLILVPISGLVLAAQFYKSSSRVATNSEVPKPVVPDVRSIPSSSPSPTPQAIPTPKTPAPAAKKNVTPPATVSIKAVGDIIPGTNFPYNKLPQKKELLFESVKPHLKGADILFGNFESTMTDHAYSSKGGGGGMLFAFRTPPSYAKILKDAGFNILNIANNHSYDFHEQGFKDTIKNIDSNGMKAVGKRDQIVYKNVKGVNFAFIGFSNYGEVHNSLLELKAGAEVVKKAKQKADIVVISVHAGAEGTGALNVRNKTEFFQGENRGNMVLFSRTMIDAGADLILGHGPHVARAMELYKGKLIAYSLGNFMGYRTLSTVGELGKSLILDVKMNPQGDFVSGKIIPIALNGQGIPSLDDDFRSVRLISRLTKSDFPNAGLSIGDLGQIVKQNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXK5</accession>
    <name>A0A2G4EXK5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_017400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000115">
        <property type="protein sequence ID" value="PHX54208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54208">
        <property type="protein sequence ID" value="PHX54208"/>
        <property type="gene ID" value="CP500_017400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POTRA" evidence="3">
        <location>
            <begin position="62"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Omp85" evidence="2">
        <location>
            <begin position="155"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="467" mass="50508" checksum="6BAE81905C537892" modified="2018-01-31" version="1" fragment="single">ARPTGVDDRQDARPTGVDASQLDGTVQVSEARDVGGIYVAEVKIRFVNSRGEAVDKKGKPIEGRISEDFIRGELKLKAGDNYSQDVVRSDLQQLQQLGLFDKVTVSTEEVGTDINVIYNVEERSARSFGVSASLSDDIGVAIPLSYIDRTLGTNPQRVSVEVQPSLRDLEYDVQFVSPYVAATDRLGYSVRTFRDRRTSDIFNDDIDLPNGNRVREIRMGANLAVTKPLGDWRGTLGLNYTNISTRDRNLKIARRDELGNPLTFSGTGVDELYTVSFGATLDRRNNPFNPTSGSILSLSTEQSIPLGQGNILSNKLLANYIRYVPMNLLGGGDSETLPEMLAINLQAGTVIGDLPPTEAFRLGGRNSVRGYDSGDIGSGRSYFLASGEYRFPVGTDVGGVLFVDFASDLGTGDSVLGQPASVRDKPGTGAGAGVGVRVRSRFGLIRFDVGVSDGGEIKFVLGTKQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXK8</accession>
    <name>A0A2G4EXK8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54274">
        <property type="protein sequence ID" value="PHX54274"/>
        <property type="gene ID" value="CP500_017030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="497" mass="57392" checksum="2BA2CEF2B4BB04D8" modified="2018-01-31" version="1">MSEINKQRLLELITNIAPGLGTAEQESNDQDKFLKNFLPIPDYRYALEPNTLLILGGRGVGKTELFRLLAIPSGRESLVESLKIRSLPDLSKTTWIAGFGRARTAEKRFPTPESVETQMNNTKNIEWRSFWIGLILGGLLQQEDFKFKDFLIEQIGTEIVNILRDDLPRLSIWQPIVNQNLENLNSILDKLDQKLIEADDWLFVTYDELDRLVASYAALAIPIRELLALWLNRWGRWDRIRPKIFLRTDLFREDFLSFPDASKLQAHQIRLEWKHSWLYQLLVKRLANSGTEMTEYLQNIPKLIIENKTGLGWTATSNEKLFEELIERMIGKYMGPNAKKGITYRWIPNHLQDAGGRIAPRSFLKLFALAAQSRIQQHSTVEQNTLLLQPSDLQGALMNTSDDRILELQEEYPWLESLKMSLVNLSAPMPKEVFLERVKSTTWIPEKQPPVTNPEGILQYLLQLGIIEGRLDGRINMPEIYLYGFQVKRKGGVKRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXR2</accession>
    <name>A0A2G4EXR2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-alanyl-D-alanine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54323">
        <property type="protein sequence ID" value="PHX54323"/>
        <property type="gene ID" value="CP500_016750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003709">
        <property type="entry name" value="Pept_M15B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02557">
        <property type="entry name" value="VanY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VanY" evidence="2">
        <location>
            <begin position="73"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="226"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="288" mass="31703" checksum="66E02A95DF469DB4" modified="2018-01-31" version="1">MPKLKDTLLINACNTGLIRGLNLQIIAVLNSIVPNLLVDFTDIEGVVAVGDKNNPFLQAAAKNSLKIAVAERRKAEGNSVQLIVNSAYRTVAQQYLLNLQFRQVSDQCGIQAVAPPGFSNHEGGLALDIQDYEGWEPYLEKNSYVWFGLGDKPHYDYRFFAATRDDIGTLGIRAFQMLWNKYNSTDMIKVDGNFGPQTEARLRESMAEGFGNPFPRVLTLQKPPMTGDDVRKIQQSLVSNKLTKIEIPINGIFDAATEAAVKQFQEATKRLAVDGAVGSLTLKALGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY08</accession>
    <name>A0A2G4EY08_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Photosystem II protein D1</fullName>
            <shortName evidence="16">PSII D1 protein</shortName>
            <ecNumber evidence="16">1.10.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Photosystem II Q(B) protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16 19" type="primary">psbA</name>
        <name evidence="19" type="ORF">CP500_016640</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>2 a plastoquinone + 2 H2O + 4 hnu = 2 a plastoquinol + O2</text>
            <dbReference type="Rhea" id="RHEA:36359"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:30212"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
            <dbReference type="EC" id="1.10.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <text evidence="16">The D1/D2 heterodimer binds P680, chlorophylls that are the primary electron donor of PSII, and subsequent electron acceptors. It shares a non-heme iron and each subunit binds pheophytin, quinone, additional chlorophylls, carotenoids and lipids. D1 provides most of the ligands for the Mn4-Ca-O5 cluster of the oxygen-evolving complex (OEC). There is also a Cl(-1) ion associated with D1 and D2, which is required for oxygen evolution. The PSII complex binds additional chlorophylls, carotenoids and specific lipids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 16">Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 16">Cellular thylakoid membrane</location>
            <topology evidence="2 16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="16">C-terminally processed by CtpA; processing is essential to allow assembly of the oxygen-evolving complex and thus photosynthetic growth.</text>
    </comment>
    <comment type="PTM">
        <text evidence="16">Tyr-161 forms a radical intermediate that is referred to as redox-active TyrZ, YZ or Y-Z.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="16">2 of the reaction center chlorophylls (ChlD1 and ChlD2) are entirely coordinated by water.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="16">Cyanobacteria usually contain more than 2 copies of the psbA gene.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="16">Herbicides such as atrazine, BNT, diuron or ioxynil bind in the Q(B) binding site and block subsequent electron transfer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 16 17">Belongs to the reaction center PufL/M/PsbA/D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.9" evidence="16"/>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54340">
        <property type="protein sequence ID" value="PHX54340"/>
        <property type="gene ID" value="CP500_016640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045156">
        <property type="term" value="F:electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016682">
        <property type="term" value="F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010242">
        <property type="term" value="F:oxygen evolving activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009772">
        <property type="term" value="P:photosynthetic electron transport in photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009635">
        <property type="term" value="P:response to herbicide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09289">
        <property type="entry name" value="Photosystem-II_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.85.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01379">
        <property type="entry name" value="PSII_PsbA_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036854">
        <property type="entry name" value="Photo_II_D1/D2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000484">
        <property type="entry name" value="Photo_RC_L/M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005867">
        <property type="entry name" value="PSII_D1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33149">
        <property type="entry name" value="PTHR33149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00124">
        <property type="entry name" value="Photo_RC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00256">
        <property type="entry name" value="REACTNCENTRE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81483">
        <property type="entry name" value="SSF81483"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01151">
        <property type="entry name" value="psbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00244">
        <property type="entry name" value="REACTION_CENTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 16" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="13 16" id="KW-0157">Chromophore</keyword>
    <keyword evidence="16" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 16" id="KW-0359">Herbicide resistance</keyword>
    <keyword evidence="16" id="KW-0408">Iron</keyword>
    <keyword evidence="11 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 16" id="KW-0464">Manganese</keyword>
    <keyword evidence="14 16 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 16" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="16" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="8 16 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="16" id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_5023554395" description="Photosystem II protein D1" evidence="16">
        <location>
            <begin position="1"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="propeptide" id="PRO_5013978707" evidence="16">
        <location>
            <begin position="345"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Quinone (B)" evidence="16">
        <location>
            <begin position="264"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>ChlzD1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>pheophytin a</name>
            <dbReference type="ChEBI" id="CHEBI:136840"/>
            <label>D1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>[CaMn4O5] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:189552"/>
        </ligand>
        <ligandPart>
            <name>Mn</name>
            <dbReference type="ChEBI" id="CHEBI:18291"/>
            <label>1</label>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>PD1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>[CaMn4O5] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:189552"/>
        </ligand>
        <ligandPart>
            <name>Mn</name>
            <dbReference type="ChEBI" id="CHEBI:18291"/>
            <label>1</label>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <feature type="site" description="Tyrosine radical intermediate" evidence="16">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes free radical intermediate" evidence="16">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by CtpA" evidence="16">
        <location>
            <begin position="344"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PHX54340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="360" mass="39769" checksum="4E9D5E2EE2681F5F" modified="2018-01-31" version="1">MTTTLQQRESANVWERFCEWVTSTDNRIYIGWFGVLMIPTLLSATICYIVAFIGAPPVDIDGIREPVAGSLMFGNNIITGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVIFHFLIGIFCYMGREWELSYRLGMRPWICVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTETESLNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFLLGAWPVVGIWFTALGISTMAFNLNGFNFNQSIIDSQGRVINTWADVINRANLGMEVMHERNAHNFPLDLAAGETTPVALVAPSING</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY97</accession>
    <name>A0A2G4EY97_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54504">
        <property type="protein sequence ID" value="PHX54504"/>
        <property type="gene ID" value="CP500_015675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="405" mass="45407" checksum="2834788CDCBD24AC" modified="2018-01-31" version="1">MQIGIFLGNVGNPVIYYPKLAKITGGVTASILLCQLFQWQSQLANSENWVQTNTAEIEKATGLNYEEQEFARQQLKARFLLKEKTPNPHAETLELWADFDVFESKLNTYFTAIPEDIITQTLPKSLNYPVEILPDNSASNPSIKTDKYFGQPRQQIAVAVTPNYRFSGPWNSQEQLHNFQRALEAYAQERNLGFGNPSGWAFKIIDSITKGLASTFWDEFIAGIPLGESQKVKRDWEIAPEVPYPAFEEERIQYYVHKGEPLEAAVSKARADLRNPVLGKDLWEGFLRKCDRLADDALKAKKQGVDTPYLPSSFNEKPQITKDSVMRKLGAIAPQFALNQSTSEPTPEPPKLPETASPTPAPSIATLQKAYNTPLGRSIIEIQIAANPDWGYEIVDGEIVESIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYA9</accession>
    <name>A0A2G4EYA9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000094">
        <property type="protein sequence ID" value="PHX54525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54525">
        <property type="protein sequence ID" value="PHX54525"/>
        <property type="gene ID" value="CP500_015635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="54"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="23927" checksum="A7B6413F41855D41" modified="2018-01-31" version="1">MNYSFFSSPTWGQQISQNYRFLVRIADSKDLTQLADILALSFHSREGFVDWVYPVLRLGIYEDLKNRLRFKTEYYICLVSELVSREENSLAKQPESIAGTVEVALRSRLAWQLPSSDYPYLSNLAVHPEYRRQGVAQQLLSSCEQTVREWGFSEVYLHVLENNHGARQLYYQTGYRLEQVEWDWSCWLLGQPRRLFLRKKLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYE7</accession>
    <name>A0A2G4EYE7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54516">
        <property type="protein sequence ID" value="PHX54516"/>
        <property type="gene ID" value="CP500_015735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="11800" checksum="6C574E8297A7B5C9" modified="2018-01-31" version="1">MSRYFLSTQAKYDLREIKNYIARDNLAAARRFVETFRDQCNLIAKSPRMGRSYEELAPGLRGFAIGNYIIFYRPIENGIAVERLLSGYRDLEAIFYEDDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYQ7</accession>
    <name>A0A2G4EYQ7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54654">
        <property type="protein sequence ID" value="PHX54654"/>
        <property type="gene ID" value="CP500_014950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="189" mass="21935" checksum="B79A570122DBCD78" modified="2018-01-31" version="1">MSKRKKQEWLKETLELKENHNWKSKPGTRIFVAGRGAVRFDVPDDWHFEPDTKSFRFTDKKPPDDDCGLEVSFNLLPPGNWADFPLAPLLKQVAEEDSRNPFDMGEIIQLNRQTARIVWTEFKFIDPPEQREAYSRICVGLGSNVQCLITFDYWVDDAERLTPVWDTVMETLVLGLFISDPRTGFARPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYU7</accession>
    <name>A0A2G4EYU7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54692">
        <property type="protein sequence ID" value="PHX54692"/>
        <property type="gene ID" value="CP500_014845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="16"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="392" mass="43055" checksum="03E7F93F07345E96" modified="2018-01-31" version="1">MAEQTNATGEYTLELSILMPCLNEAETLEVCIEKAQKSLRELNIAGEVIVADNGSTDGSQDIATRMGARVVPVAAKGYGSALMGGIIAARGVYIIMGDADDSYDFSDLGAFVEKLRGGCDLVMGNRFQGGIKPGAMPPLHKYLGNPVLTWVGRLFFSSPAGDFHCGLRGFRRDAILTLDLQTTGMEFASEMIVKASLYKLRITEVPTVLSPDGRSRPPHLRTWRDGWRHLRFLLLYSPRWLFLYPGVALMVWGLIISIWLLPGTQKIGSISFDVHTLLYAAIAIIIGFQAVTFAFFTKVFAISEKLLPEDPKLNKIFRYVTLETGLIVGFVLVLIGIVGSILSLTIWKETAFGILDPSKTLRLVIPSLTCLTVGLQMVLSSFFLSVLGLKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYU8</accession>
    <name>A0A2G4EYU8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_014880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54666">
        <property type="protein sequence ID" value="PHX54666"/>
        <property type="gene ID" value="CP500_014880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="97"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="97"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="25097" checksum="552EA103CD052219" modified="2018-01-31" version="1">MFTGLIQSLGQLKSLGNDRFQVSCTSSNSHQILEDLAIGDSVAVDGVCLTVVSVLPQGFVAIASPETLRRTNIASSPDASVNLETSLRAGSKLGGHFVTGHVDAIGALATSTQTANAWEMRFTAPATANSGWQTQIAPYLVSKGSIAVNGISLTVADCDADGNWFEVAIIPHSFGETNLRYLQPGSLVNLEADILAKYVAKFLRSGGSKLHPEPWEETPAINSLAGITPDFLAEHGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ51</accession>
    <name>A0A2G4EZ51_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1822 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54780">
        <property type="protein sequence ID" value="PHX54780"/>
        <property type="gene ID" value="CP500_014255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014951">
        <property type="entry name" value="DUF1822"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08852">
        <property type="entry name" value="DUF1822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="124" mass="13412" checksum="804FC76DFF5B0FEF" modified="2018-01-31" version="1">MATFARSGARSGDNEERTPGISRGRVIDLGIQLAGHPVALIVHFTKESENKCNILLQVHPGGGKTYLPPDVELIVLDDAGGVFLEAKSRLADNWIQLEFRGEPGERFSVKVALGDASIVEDFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ87</accession>
    <name>A0A2G4EZ87_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CP500_013990</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54835">
        <property type="protein sequence ID" value="PHX54835"/>
        <property type="gene ID" value="CP500_013990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="18" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="17">
        <location>
            <begin position="124"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="17">
        <location>
            <begin position="309"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="434"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="15">
        <location>
            <begin position="484"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="537"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="15">
        <location>
            <begin position="612"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="1048"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="13">
        <location>
            <begin position="1346"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="13">
        <location>
            <begin position="1545"/>
            <end position="1662"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="16">
        <location>
            <begin position="1719"/>
            <end position="1818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1667"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1008"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="1594"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="7">
        <location>
            <position position="1758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PHX54835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1831" mass="204170" checksum="6FADFEB9FD996749" modified="2018-01-31" version="1">MFIPSLNQVINRNPLIVTPQTPIEEAIELMSRTGASYVLVLEQRGNFQRESWTNGHSALARKNLGFYDNVPRPVHSELKGRSFKGSKPTYPADGPVLGIITERDIVQLNSIGASLKGFAIEQIMIRTVTVAKESQIPDIFALGSLLEKNQIGHLPIVSEIDELVGIISTQSLLQMLQEAGNSKQKAVSSASPPQTLLAPPPPVPNLHPKLELPAHSIKLYQIPRIAASRIIHAPVTSSVRYLAQLMFRNNVNYVLITETAEQNSTETAHNSKITNNNSQKLVGVVSTRDIVLLQALGIDSNQTTAGTICSSPPALVRPYQTLEAAIALLQKTCCQLPLLVVNENGHPIGIVNPKTILLQALDSKSLHSGLIALQRQLESTTAQYKKLSSEVKIAAAHRQQVEQVTQNSSDLANLAIQINNQGIWNWNIETDECFYSRRWKEMLGYSESEIDHRRSEWWSRIHPNDLDSVKAALEDHLAEKTADFVTEYRMQCKDGSIIWMLNRAQVLRNGVGKPLRMVGTHTDITQKKELEVKVRENEQQQSEIFDSLKATVIFQMDAGGVWTFLSRAWTEMTGFSVSESLQTNFLDWVHPNERQQCAKILESLVARRLEFHRREVQFMKRHEIGFEDSGNKISSRFISVEMFAQTRLNSEGEITGILGTLHDVSRRVEGVEELRESERAIRSLYEVMVSSQGSFDERTERLLAMGCSQFGMDIGLLGRVLGDRYEVIAAYLPEDFPFGFAKGDGFALSRTFEREVLRSPEPISIESAGTTQWRHHPAYTVRRLEAFMGTRVMVGGRVFGTLSFTARTAKAPLKPLNLEILKLMGNYIGTEIAREEKERTLERQYQRGLLLKQITQKVRSTLDTQEIFQTTATQIGRVFGVNRCTIHTYLVEPYPHLPCVAEYLEPAYESALDLELSVTYNPYTEKLLSEDIALASPDVFADPLLESSVPMCRRIGLKSMLAVRTSYQGKPNGIITLHQCDATRQWNPDEIELLEDVAAQVGITLAQAKLLETEVQRQQQLAEQNEALDQARQAAEVANQAKSEFLATMSHEIRTPMNAVIGMTGLLLDMALTTEQRDFVETIRNSGDALLTIINDILDFSKIESGKLDLENQPFELQNCIEESLELLAPKASEKGLELAYLIDSSVPKKILGDVTRLRQILVNLLGNAVKFTESGEIVVRCTAREVQPGMAVSSPSHDNFLEQEQLIINQERLAVNQKYEIQFAVQDTGIGIPPERMNRLFKAFSQVDASTTRQYGGTGLGLAISQRLSDMMAGKMWVFSQVSRGNSNFQMSLPEFGKSVVGQAPVGFVEPSISGTGSIFYFTVMAEGIEGIPHEKQPDFATGKHLLIVDNHAINRQVLISQAQSWGMIPVTASTAAEALEIIQQNSEIDLVILAMNLLDMDGVALAVEIRKLEIENFLKVGEQLDTNGISITSNRKSPLPLVLFTYLSKAEVWKKLENTEVHFAAFLTKPLKQSQFYNVLVQVFGYVTGRNSMGEFSNVATLTSGLQYFENSQEQHRIQHTPAILRQIASNLSQGGANGVQIRILLAEDNVVNQKVAIHLLDRIGYRADIAANGLEVLEILRRQSYDVVLMDVQMPEMDGLEATRRICQELSANKKPRIIAMTANAMQGDREKCIEAGMDDYITKPVRREELAIALSKCQPLNRDEGTAVTESQNGAGTRKFNSESATVSSSVHRENVSPIDFQILHNLRELDDDDDPNFLGDLINIYLSDAPQHLKIMKEAIFLGDADSLKLASHTLKSSSANLGALSFSDVCQELESISRAAVESGGDQTFDVGIARDWLFEAEVEWEKVRMAFERELETRNLRSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZE2</accession>
    <name>A0A2G4EZE2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54880">
        <property type="protein sequence ID" value="PHX54880"/>
        <property type="gene ID" value="CP500_013675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014056">
        <property type="entry name" value="Addiction_killer_pred"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41791">
        <property type="entry name" value="PTHR41791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028744">
        <property type="entry name" value="Addict_mod_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02683">
        <property type="entry name" value="upstrm_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="13143" checksum="35670D930E665B8C" modified="2018-01-31" version="1">MEVQPREIRRYIKPNGTVPFAEWLAALRDVNAKIRIDKRLLRVRNGNLGDCRSVGEGVYELKIDYGPGYRVYFGQAGFTIVLILCGGDKSTQDQDIVRAKEYWKDYEIRESADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZT9</accession>
    <name>A0A2G4EZT9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_012970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55021">
        <property type="protein sequence ID" value="PHX55021"/>
        <property type="gene ID" value="CP500_012970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="PTHR10887"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_11" evidence="3">
        <location>
            <begin position="600"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_11" evidence="3">
        <location>
            <begin position="1279"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_12" evidence="4">
        <location>
            <begin position="1486"/>
            <end position="1689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="700"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1724" mass="194699" checksum="5A546420C37953BC" modified="2018-01-31" version="1">MPTFSADPSNFGEFLTIVKDGYEIDLKAGEYKGPFTIEKAIVLRGEGENTVIFATDEPVLKIAVSGVKLENLSIERNIGGNMGEIAIDAAPHTAPVLDRVRCLGSAPNVQWLGVSWDIPTAVHFGEIQTNRYLQRTEQLQLGGDCKVSCSAPWLQVQQPYLSCGLQKLDIVLNSQDLPAGTNLSGSIVLQASSHNVSIEISAIVTAPQTSNNPSPLSSQTATEPVNNNDENWGYRFLGNQAIDYLIREMEGKDALEKYSEFSDRRDRAEDLLSDILGDEPRLFYVRRKGPGEAPGEEKWELAIATDIEAAKLPEILEKRQKTLSLVALVTEGRSDGLRLLSARLVASERGRSDGFSVLFSLSLHLNHQSRRPVPISALNLMQTVPFCGDCVPTEEQLKGWRAFLKIEERIAKTREFFVPFYGHNYGSATRKITFEITVSEAKLDRSSGIYLKQDDFWTRAAKARNEDIKLVVRVEESREKDDSTSERESVPQPAKWQAILLGSIEEIDKAKGFIRVRLDSELVEKIGEGHYQLPKTGFLSFEAAGDLTQIKRQKKALDDLQMGIAQNPYVGEFFFDASQARNPQTTVKLKPEDLLLSGANDDQVAAVEAVLSAPDLVLIQGPPGTGKTTVIAEISYQVALRGGRTLIASQANLAVDNALSRLIHSPVIRALRKGRAERVEEEGLPFVEDKVIGNWLRNTADDCEKRLAKQRENIEFFNDLLANSERFDAYLRTEEKLQESYKELELRSRKAELEENCREHESVYQEAEAKQREVVEYILPGLKLLMSQSSINWEDETVINLWKTAIKICNSTELLILGYNSEESFKVKVEKAAKMAADLGVQTANLRLNYLSLAAWLKEQGLPQNKMSLSHCRDAISSIREAAEPERSLRDKSVALLLLETNYQPSLTKLKNLEESINTWEKRKLRTVAVSSTINQWKSTVYDRVYAAMKQCLDTNRVFTDDLIHLPLDVVSFVKANPAPWRSHLDRCKSKIANLSKSEAKKISAFEPQLDALAKEAIGGIAATARNWLNQQQELEQNQKNSVLKALNKWESTAYQSVYEELKKCVQEQRKFTDNLIKLPPELLASVPVKPHPWRSNLDRCRSKVASLIAKQSEVQTPNFDADLNSIATEAIESIAASISQWLEQQQPETEKQLQNLKKQLKQHQQATTKQQQEIATAKKQLEDLQRLSPTKAQRAMQVLAELGKRSGIPANIRILAMRYQSFPSLSKAIAHTPVSEFTQRSKLWEERISQFEQLISSLDPLLGLLVIEEALTTIQARLQQAASQAFNQLQESQDMLQKMDVQLQQLQQKQQLPPNLISERKWWESAWQNIPDRLKPPIPDSGLFDLNFLHEIKTQFDAWHQQLTQEESHLKGYENLTQDWIAKLRNPSEQDQSELRQVYIENANVIGITCSQVAGYGFKEFTNFDVVIIDEVSKCTPPEILIPALKGKKLVLIGDYRQLPPMLHEKSLEEIATEMGIEPEDISFLEESLFKKQFEAASESIKRRLTVQYRMHPYIMGAINQFYDHSLRCGIMEPEKVRSHNVAGDIIRAEHHLIWVKMPQEQRFQEQLEGTSRYNLKEVDAIDILCEQMEDVWSLKVAEGQPKKEIGIITFYGAQLRRIEEMLSDRKFPSLSIRTGTVDRFQGMERPIIIVSMVRNNPDGDIGFAKKPERVNVAFSRAQELLIIVGCHSLFTKHKGKVGSMYSEVANIVRRNGGLIDVSSVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZY3</accession>
    <name>A0A2G4EZY3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_014335</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245906">
        <property type="entry name" value="M.Tbo703ORF14335P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54757">
        <property type="protein sequence ID" value="PHX54757"/>
        <property type="gene ID" value="CP500_014335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <keyword evidence="5 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7 9" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="7">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="333" mass="38083" checksum="425A7B30897C3607" modified="2018-01-31" version="1">MLISMNIISLFAGCGGLDLGFRLAGFNPVWANEYDRTIWDTYQFNHTDTLLDRRDIRKINSDEVPDCVGIIGGPPCQSWSEAGAKRGIDDSRGQLFWDYIRIVRDKQPLFFLAENVSGILSPRNRDAFTYILSQFEQIGYRVSFKLLNAKNFGVPQDRQRVIVVGYRESLGFGFEFPEPGNEVLTLKDAIFDLRAIAPIAVKGKVDHYHNSVPNHECADLGFSSIYMSRNRVRSWSEPSFTIQASGRHAPIHPQANKMILVSQDKRIFDPNSPQPYRRLSIRECARIQTFPDEFIFKYKYIIDGYKMVGNAVPVKLASRLANKIFEDMKICHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F074</accession>
    <name>A0A2G4F074_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4065 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55148">
        <property type="protein sequence ID" value="PHX55148"/>
        <property type="gene ID" value="CP500_012245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025272">
        <property type="entry name" value="SocA_Panacea"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13274">
        <property type="entry name" value="DUF4065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4065" evidence="1">
        <location>
            <begin position="28"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="151" mass="17585" checksum="2CD17854770DB36C" modified="2018-01-31" version="1">MKSAIEIARYFLCRVDREVGDIISLLKLQKLVYYAQAWSLVFRSQPLFYQDIEAWVSGPVVRDVWHEYEAYKYSDIPSPNNFDEEFDEDESEVLEEVWNAYGELSAKHLAELTHSEMPWLNARQGLEIAEKSTNIISHDDMKSCYAPLVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0B7</accession>
    <name>A0A2G4F0B7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4340 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55188">
        <property type="protein sequence ID" value="PHX55188"/>
        <property type="gene ID" value="CP500_012055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025641">
        <property type="entry name" value="DUF4340"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14238">
        <property type="entry name" value="DUF4340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4340" evidence="2">
        <location>
            <begin position="77"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="209" mass="23414" checksum="79D9ADAC079342B8" modified="2018-01-31" version="1">MKLQKNTLILIAVALSLTGLVSLFEIQVAPQQEAAKDEKQRIFAFKSDRIQFFTVKTPENILTFERVYAKKGGKSSWEMKVPAQAHANQASVDFLLDRLGTGKSDRTINITPSQLAEFGLDKPQATVTVKLDNQETHRLVLGNKTDFSGRFLYAQANPTESPSQNFPVILVPFDFKNATQRPLSEWKKAEEPKTDKKPKPSPTPSPENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0F3</accession>
    <name>A0A2G4F0F3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55241">
        <property type="protein sequence ID" value="PHX55241"/>
        <property type="gene ID" value="CP500_011705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="79"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="202" mass="23591" checksum="5625456B8DDCAC62" modified="2018-01-31" version="1">MAEITKEEMRERLGNIDQIRDIIFGAQLREYDNRFDKIDSDLSMMQQDMQTRTEQIKTVLAGEMRAAVDSFEKKIKSITLNTQEESADLRQQIDRVNRKFSSSIEALDEAIDNQTSSLRDELSQTRDRLSEESRTLKTQVFEELDRRFSMLRDVKVSRDDMAEILFELGMRLKGTEFVPELKGVTDNKLNSDFLLPDRHHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0G4</accession>
    <name>A0A2G4F0G4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55252">
        <property type="protein sequence ID" value="PHX55252"/>
        <property type="gene ID" value="CP500_011770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12776" checksum="A899B3D658764AD4" modified="2018-01-31" version="1">MLIPNAKNAVVDIRKLRDYCLNLEHDDGKHKARLFSSIMGMTADDAEELRQILLEVVKTHEARLGRQDEFGQRYTLDFSIEWQNRNATLRSGWIIERGSEIPKLTTCYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0P3</accession>
    <name>A0A2G4F0P3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative bicarbonate transporter, IctB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ictB</name>
        <name evidence="4" type="ORF">CP500_011290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55344">
        <property type="protein sequence ID" value="PHX55344"/>
        <property type="gene ID" value="CP500_011290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006007">
        <property type="entry name" value="Inorganic_carbon_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00947">
        <property type="entry name" value="2A73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="360"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="451"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="480" mass="53770" checksum="22E9B2D14181D269" modified="2018-01-31" version="1">MNSVWQQLTLVNLPLLQWQNASYLFNFAIGSLRSWRQSSWLMQWAEPLGFVLLALTFGLGPFVNNALVGVLMAAGAAFWVLLTVSDDRAIALTPIHLLVFLYWGIATVATAMSPVKVPAFTGWNKLTLYLLFFALMARILRSPRWRSWLIAVFLNVSLIVSFYGVRQWIDKVPPLATWNDPTSTQANVTRVYSFLGNPNLLGSYLLPAIALSAAALFVWKGWGTRALALTMLIVNCACLRYTDSRGAWIGFVALLVVFLVLLWYWYSPLMPRFWRTWALPLGLGGLAGALILGVVLVAPLRDRVSSMFIGRGDSSNNFRINVWTAVIDMIRDRPILGIGPGNTAFNKVYPLYMKPKFTALSAYSVLLEILVETGFLGLTCFLWLLTVTINQGLLQIKNLRDAQFNSLNSQEEYPNSQSNQAFWLIGAIATLIGMMAHGFVDTVWYRPEVNMLWWLMVAIIASFYSNPPQPDSASTTDRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0R2</accession>
    <name>A0A2G4F0R2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RDD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_011325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55328">
        <property type="protein sequence ID" value="PHX55328"/>
        <property type="gene ID" value="CP500_011325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="13"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="19323" checksum="A093C2E427CE3AF6" modified="2018-01-31" version="1">MSSDLVPLLPKVTIGRRAAAFCIDGFAVWLPSLLLGTNPIAQIIFFVLLWLIMRVAIVRKNRGQSLGRWAVDIKIVDPRLDRTPGLQELSKREALLGGCAALAFVALGGLTSTNAGVVLLMLPLAIDCSVAFTDTARFPQAFHDRISGTIVVGTRRGYSLDIKVKRLLDQVQSNVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0X5</accession>
    <name>A0A2G4F0X5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aminopeptidase P family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_011100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55410">
        <property type="protein sequence ID" value="PHX55410"/>
        <property type="gene ID" value="CP500_011100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP_N" evidence="6">
        <location>
            <begin position="9"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="50372" checksum="F1777A3FE4FB62A4" modified="2018-01-31" version="1">MQNFNNYDLLTTALRQRRQKLANLIDFPVILWSGSSISRNYPALKFPFRASSHFLYFAGLPLENAAIRLESGKLELFLDDALPSSTLWHGEMPKRAEIAELIGADADFPMAQLKLRSANAATIAVQDSLIQSQQSQMLDRPLTPSKSPAGIDLELTKAIISLRLTQDAASLAELRAAAAVTVEAHKGGMAATRKPQIEAGVRAAMESVIISQNMTTAYPSIVTVHGEVLHSEHYHNALQTGDLLLADVGAETSMGWAADVTRTWPVSGKFSPTQRAIYDLVLSAHDACIDKISPGVEYQEIHLLAARIMAAGLVDLGILRGNVEDLVAMDAHALFFVHGIGHLIGLDVHDMEDLGDLAGYEAGRVRSSRFGLGFLRLNRVLQEGMLVSVEPGFYQVPAILNNLETRIKYKDCVRWDELEKFADVRGIRIEDDILVTDSGREVLTAQLPTKALEIEDLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F126</accession>
    <name>A0A2G4F126_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55456">
        <property type="protein sequence ID" value="PHX55456"/>
        <property type="gene ID" value="CP500_010780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="10614" checksum="B2E78ED53A0FD533" modified="2018-01-31" version="1">MEYLIAAILFGMLIWAGLEIVQTIKSWDMNATETHRKIQAGMVKETAYGQFGGDAVEGASHAIENTLHASQCSAQTADCEVSAGAIGPTVEGLMHLMHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F153</accession>
    <name>A0A2G4F153_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55476">
        <property type="protein sequence ID" value="PHX55476"/>
        <property type="gene ID" value="CP500_010660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="60"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13188" checksum="80E09FAA1F1A8FE7" modified="2018-01-31" version="1">MVGQQTFSILLAVLVLLVLTGIGGANYASGGDEACHTNDCHEPQRKSHKPHKRILKHGSRGEDVKKLQKILNARGLCPQPIVIDGVFGPTTLTAVKKFQRQAHLPVDGIVGGKTWDKLFASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F158</accession>
    <name>A0A2G4F158_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rqc2 homolog RqcH</fullName>
            <shortName evidence="1">RqcH</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rqcH</name>
        <name evidence="3" type="ORF">CP500_012110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Associates with stalled 50S ribosomal subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NEMF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55197">
        <property type="protein sequence ID" value="PHX55197"/>
        <property type="gene ID" value="CP500_012110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00844_B">
        <property type="entry name" value="RqcH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043682">
        <property type="entry name" value="RqcH_bacterial"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="NFACT-R_1" evidence="2">
        <location>
            <begin position="492"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="609" mass="68969" checksum="C9FE50AA28563ACA" modified="2018-01-31" version="1">MQPVDLTTLTAACSELRAQWLPARLEQVYQRDRFTVSLALRTMNQRGWIDLSWHTVAARICVGDPPPRIPDTFTFSQQLRHQLSGLALVSIAPISPWERVIDLQFAKRPGEPALWHLYAEIIGKYSNVILTAQDNLVVTCAHQVSAKQSSVRPIQTGQPYEMPPALTDTTPSAIEPQNRWQERISLVPGQLQRNLLKNYRGLSKALVLSMIRSASLDPEQSTDSLSPHDWQQLFHRWQYWLQALENSTFKPSLTAQGYTVIDWPTPENHHVGAVPPCPPSDSLQTSIGLTSVKSVTESVAELPSSFKSVQELLNSYYTGEINQQVFAQVRHQLTQKLNNVLAKLNLKANTFKEKLQQSEVADTHKSQADLLMANLQHWQPGMKVISLPDFETNEPVAIPLNPEKNAVQNAQALYKKHQKLKRARIAVEPLLAAVQEEIDYLEQVEAALSVLETYRNTQDLQTLAEIREELIQQKYLDAPDYRSTDKNAAIEFHRYQTPSGFELLIGRNNRQNDQLTFRVAGDYDIWFHTLEIPGSHALLRVTPGTVAEEADLQFAANMAAYYSRARQSEQVPVVYTEPKYVYKPKGAKPGMVVYKQERIVWGRPQQATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F159</accession>
    <name>A0A2G4F159_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glutathione reductase</fullName>
            <shortName evidence="11">GRase</shortName>
            <ecNumber evidence="11">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">gor</name>
        <name evidence="14" type="ORF">CP500_010355</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Maintains high levels of reduced glutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>2 glutathione + NADP(+) = glutathione disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="8">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55500">
        <property type="protein sequence ID" value="PHX55500"/>
        <property type="gene ID" value="CP500_010355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006324">
        <property type="entry name" value="GSHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01424">
        <property type="entry name" value="gluta_reduc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0274">FAD</keyword>
    <keyword evidence="3 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 10" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="13">
        <location>
            <begin position="5"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="12">
        <location>
            <begin position="337"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="173"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="9">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX55500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="447" mass="48369" checksum="64E87B7595BE7E4A" modified="2018-01-31" version="1">MTYDYDLFVIGAGSGGLASSKRAASYGAKVAIAENDLVGGTCVIRGCVPKKLMVYASTFSHLYEDAIGYGWSPVESSFDWEKLVTTVDTEVRRLSKLHISFLEKAGVELISGYAKFIDSHTVEVGDRKITAAKILIAVGGEAHRIDIPGIEHAITSREIFLLKEQPKRLAIWGGGYIGVEFACIMNGLGSQVTQIIRRDLILNDFDAEIRTNVQEGMVKHGVEFLTESSIAQIEKTPEGLKLTLSGKSAETLTVDALLCATGRWPNLEKLGLENAGVETEKGAIAVTKDSRTNQPHIFAVGDCTNRINLTPIAIAEGRAFADTEFGNNPRSISHENVASAVFSQPEAATVGLNEEQARAKFPESIKCYTAKFRPMFHALTGADEKTFVKLVVETNTDRVLGVHMVGKDAGEIIQGMAIAVNMGATKKDFDATIGIHPSTAEEFVTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1C4</accession>
    <name>A0A2G4F1C4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Secretion protein HlyD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55553">
        <property type="protein sequence ID" value="PHX55553"/>
        <property type="gene ID" value="CP500_010225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="8444" checksum="581A3E507946079D" modified="2018-01-31" version="1">MTKNHQDSLFTEITDAESATVSGGGITNGISDINSDINSDININGSSEGINMLFFVPPSSQLYMYDPSRARPYKTLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1N8</accession>
    <name>A0A2G4F1N8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF697 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55666">
        <property type="protein sequence ID" value="PHX55666"/>
        <property type="gene ID" value="CP500_009660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021147">
        <property type="entry name" value="DUF697"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05128">
        <property type="entry name" value="DUF697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="474" mass="51498" checksum="A1470BF82D88BA2A" modified="2018-01-31" version="1">MTLNLRRPILIGGIGLSAALWLLESLQHSASEMGETGLIGLVAAGAGYWWWQRQSPKVEIPLPEALASRETALKAIASSEAAINLLASEAQNSIAPAHLKAQLDRLTAELDRPDLRISVTGGKSVGKSALIQVLNSDWISQQSHKLTFQETAPLFTTTNSDVKISDDLVLFVTAGDITDSEFQTLSQLASTGQRFLLVWNKQDQYLPAQQSQILDSLQTRMDGILGTEDIIAIAASPNSIKVRQHQADGTLTERMETQVSQLQPLTAKLTQILTAERPQLVWANTVRSAQTVKSEAKILLNAVRRDRAMPIIEQYQYIAAAAVFANPVPALDLLATTAISTQLVIDLGVIYQQKFSLDQAKTVAATLASQMFKLGLVEISTQTITGLLKTNAVTFVAGGAVQGISAAYFTRIAGQSLIEYFQSRELENTVNGGLNIDQLTKTLQAVFKQNQQISFLQTFINQIASSLSPQTSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1S9</accession>
    <name>A0A2G4F1S9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cysteine synthase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_009385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55698">
        <property type="protein sequence ID" value="PHX55698"/>
        <property type="gene ID" value="CP500_009385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="10"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="324" mass="34466" checksum="635A46E779463FAA" modified="2018-01-31" version="1">MDIKNGFIGTIGNTPLIRLNSFSDETGCEILGKAEFLNPGGSVKDRAALYIIKDAEEKGLLKPGGTVVEGTAGNTGIGLAHICNAKGYKCLIVIPDTQSQEKIDALKTLGAEVRTVPAVPYKDPNNYVKLSGRLAAEMENAVWANQFDNLANRRSHYETTGPEIWEQTDGKVDAWVAATGTGGTFAGVAMFLKSKNPEIKTVLADPMGSGLYSYFKTGEIKTEGSSITEGIGTSRVTANMENAPVDDAIQIDDAEAVRVVYQLLRKEGLFMGGSVGINVGAAVALAKQMGAGHTIVTVLCDGGARYQSRLFDRQWLTSKGLSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1U1</accession>
    <name>A0A2G4F1U1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55447">
        <property type="protein sequence ID" value="PHX55447"/>
        <property type="gene ID" value="CP500_010730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="4"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="14504" checksum="54337B28B049AEA0" modified="2018-01-31" version="1">MPLKYLLDENVDPIYKVGLSKNESDLIVWAVGEPHCPRRGTLDPEILLWCQEYNFILVTNNRKSMPVHLVDHINESRHIPGIFLLNVKLTVGQNIDELIFLAQVSFEGEYQDQIIHLPHSYVLGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1W3</accession>
    <name>A0A2G4F1W3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Photosystem I reaction center subunit VIII</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_010595</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May help in the organization of the PsaL subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cellular thylakoid membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PsaI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55467">
        <property type="protein sequence ID" value="PHX55467"/>
        <property type="gene ID" value="CP500_010595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001302">
        <property type="entry name" value="PSI_PsaI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036357">
        <property type="entry name" value="PSI_PsaI_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00796">
        <property type="entry name" value="PSI_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81540">
        <property type="entry name" value="SSF81540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03052">
        <property type="entry name" value="PS_I_psaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="38" mass="4217" checksum="CD61CA3DC1C65CDD" modified="2018-01-31" version="1">MTGSYAAAFLPWILIPLVTWVMPIVVMGLLFIHIESDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1X9</accession>
    <name>A0A2G4F1X9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55756">
        <property type="protein sequence ID" value="PHX55756"/>
        <property type="gene ID" value="CP500_009125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="12856" checksum="9468A2B8C0BD6908" modified="2018-01-31" version="1">MTEDYIVIVTDEADEASVPIEGQRGWGEEVRKRISSLKEVRLPVAQLEQNMAQFLHLIGRLFKQVDREIGSESGMKLDEVELSVEISGEGEVKLVAGGKATGKGAIKLKFTRLDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Y8</accession>
    <name>A0A2G4F1Y8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mgtE</name>
        <name evidence="9" type="ORF">CP500_009170</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55762">
        <property type="protein sequence ID" value="PHX55762"/>
        <property type="gene ID" value="CP500_009170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="153"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="217"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="465" mass="50501" checksum="68F3436CEC03F84A" modified="2018-01-31" version="1">MTESNYQLSSLPTYARKELRELVRSQLKALLEQADFKGAKAILQPVQEADIAEAIEGLPETMQVIAFRLLAKDEAIAVYEYLDSSVQQSLCEKFKRQEVIDIVDKMSPDDRAKLFDELPAVLVRRLLGELSPTEREATAQLLGYEASTAGRIMTPEYISLKESFTVTQALDRIRSLAKTTETIYSLYVTDAARSLTGILSLRDLVTSPLDKTVGEIMTREVISVQTGTDQEEVARLIQRYDFLAVPVVDREQRLVGIITVDDAIDILEQEAAKDIYALGGVQSGGDNYFQTDLITVARKRVVWLFVLLLTNTVTGSIIRAQEDLLQQVVALAAFIPLLTGTGGNVGAQSSTVVIRGLNTDEITAMGPMKIIVREGMAGALLGAILGTVATAWAYVLQGNLAVAIAVGLSLLAIAMLASIAGSALPFLFRSLGLDPALMSAPFITTAVDVLGVLIYFSLARLILQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F235</accession>
    <name>A0A2G4F235_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="10">2.2.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-deoxyxylulose-5-phosphate synthase</fullName>
            <shortName evidence="10">DXP synthase</shortName>
            <shortName evidence="10">DXPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dxs</name>
        <name evidence="12" type="ORF">CP500_008670</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:12605"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="10">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55821">
        <property type="protein sequence ID" value="PHX55821"/>
        <property type="gene ID" value="CP500_008670"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052865">
        <property type="term" value="P:1-deoxy-D-xylulose 5-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02007">
        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00315">
        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="11">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="113"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="145"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX55821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="635" mass="69215" checksum="6B8BAE20B77E0B53" modified="2018-01-31" version="1">MHLSELTHPNQLHGLSIHQLEQIARQIREKHLETVATSGGHLGPGLGVVELTLALYQTLDLDRDKVTWDVGHQAYPHKLITGRYNQFHTLRQKDGVAGYLKRCESKFDHFGAGHASTSISAALGMAMARDLKGENFKTVAVIGDGALTGGMALEAINHAGHMPKTNVMVVLNDNEMSISPNVGAITRYLNKMRLSQPVQFLKDNLEEQFKQIPFVGETFTPEMERLKEGMKRLAVSKVGAVIEELGFTYMGPVDGHNLEELIATFKHGHTIQGPVLVHVVTVKGKGYAIAEKDQVGYHAQNPFNLATGKGIPSTKPKPPAYSKVFAHALVKLAENNPKIVGITAAMATGTCLDKLQEKLPKQYIDVGIAEQHAVTLAAGLACEKMRPVVVIYSTFLQRGYDQIVHDVCIQNLPVFFCLDRAGIVGADGPTHQGMYDISYLRCLPNLTIMAPKDEAELQRMVVTGVNHTSGPIAMRYPRGNGYGVPLMEEGWEELAIGKAEILRNGDDLLILGYGSMVYPAMQTAEMLSEHGIEATVINARFVKPLDTELILPLAQRIGKVVTMEEGCLMGGFGSAVAEALLDNNVLVPLMRLGVPDTLVDHATPEQSFATLGLNPSQMCDRILATFSRKQSPVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F252</accession>
    <name>A0A2G4F252_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55826">
        <property type="protein sequence ID" value="PHX55826"/>
        <property type="gene ID" value="CP500_008710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="222" mass="25087" checksum="6FD50145E4F657D6" modified="2018-01-31" version="1">MKPKAVLVETNWVVDVVAPAYLQSPQAIQLLQRAQAGEFKLYLPAICLAEARETVPRRFAPRSRSDDLRKFIKWARDEARVNSEDADAAYRVFAQFDGLVANELTKVKVSERLDELANHPSLNVFPLSEPMLERQISIGAMDLSLKPFDLAVLAAVIVKSEELQQEGHAWVGFCELDSDLQPWDKSGARKRILSDLYDDVRILVYADFLLEDISELPDGWTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F256</accession>
    <name>A0A2G4F256_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HEAT repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55854">
        <property type="protein sequence ID" value="PHX55854"/>
        <property type="gene ID" value="CP500_008450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="424" mass="47343" checksum="C33A2FE66F7C5291" modified="2018-01-31" version="1">MDKRFFSFFNLTEDQAIALLDTPQAEIGEEDSRYIAASHLINFSTDRSIAALIRAVQQTDPVLENRIVRRKSVETLGRLQAVLALPVIRTCLADNDCYTVENAVWAIGEIGTQDADVLEEVAQLLDKPGQTYRVIIHTLTKLDYQPALARIRRFVDDIDPPTASSAIAAICRLTRDFSQMGKVVAMLQHKNVLGRRLSIQDLIDARYYDAIPNIARCPVSLVFRLRGIRMLASAGIADKSLTFATIQPYLEQTLRDYPADLDLVHSYEKLPDLSFLIRQLYETDFGRCYLAAKTILENYSEEAPAALFATFAEEANNDYGAHFHVVKLFGWLKHSAAYDLLLEALNNSQPQFQKSRAAAAIALGELGEQRAIPALKACLETKIWDLKYAALMALEKLGDFSGYAIAAADQDWLVRAKIDAHTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2C4</accession>
    <name>A0A2G4F2C4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55899">
        <property type="protein sequence ID" value="PHX55899"/>
        <property type="gene ID" value="CP500_008365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8736" checksum="EEC56B28C7CB4737" modified="2018-01-31" version="1">MLQSVEGIYRNGKIELLETPADMEEVQVIVTFMPKSGLVNLQSRGIDREQAADLRVRLRRFAPDWELPEMDAYDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2D4</accession>
    <name>A0A2G4F2D4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2862 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55921">
        <property type="protein sequence ID" value="PHX55921"/>
        <property type="gene ID" value="CP500_008065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021291">
        <property type="entry name" value="Tsr0524-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11061">
        <property type="entry name" value="DUF2862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7397" checksum="2340EBBC7FE694DA" modified="2018-01-31" version="1">MAIEVGQRVKVRRLRDRIPANIVGKLKTNPVGTVDSFRMVDGSGVGLVVKFDDFATWFFEDELEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2F1</accession>
    <name>A0A2G4F2F1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arsenic-transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_008070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arsA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55922">
        <property type="protein sequence ID" value="PHX55922"/>
        <property type="gene ID" value="CP500_008070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="Anion-transp_ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040612">
        <property type="entry name" value="ArsA_HSP20-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17886">
        <property type="entry name" value="ArsA_HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArsA_ATPase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="ArsA_HSP20" evidence="3">
        <location>
            <begin position="308"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="366" mass="39703" checksum="6295F8DF5C54F1A2" modified="2018-01-31" version="1">MALILTFLGKGGTGRSTIAIATAKKYAAQGKRVLLLSQDPGPGLGILLGTVLTSSPQEIAPNFKAVQVQSAPLLERRWDEVKQLEAQYVRTPFFKQIYGQELGVLPGMDSALALNELREYDDSKQYDAIVYDGTGGMDTLRMLGMPEILSWYIRRFRKALIDSDLGKTLALSPFIQPLITTVLTVDLSGDNASKSTQQVDNFLDKGKEILANPNRTAAYLVTNGDASAIATARYLWGSSQQIGLTVGGVILNQVPITEAIAANFDPLTAVSVPAHSENNWQPLIDALPDFSEAARAPKAIDINIAQRQVSLFLPGFDKKEIKLIQSGPEVTIEAGDQRRNILLPPQLTGKSVTGAKFLNSYLIVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2I6</accession>
    <name>A0A2G4F2I6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase</fullName>
            <shortName evidence="6">Mg-protoporphyrin IX monomethyl ester oxidative cyclase</shortName>
            <ecNumber evidence="6">1.14.13.81</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">acsF</name>
        <name evidence="8" type="ORF">CP500_007885</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>2 H(+) + Mg-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 O2 = 3,8-divinyl protochlorophyllide a + 5 H2O + 3 NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:33235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58632"/>
            <dbReference type="ChEBI" id="CHEBI:60491"/>
            <dbReference type="EC" id="1.14.13.81"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; chlorophyll biosynthesis (light-independent).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AcsF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.81" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55958">
        <property type="protein sequence ID" value="PHX55958"/>
        <property type="gene ID" value="CP500_007885"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00670"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048529">
        <property type="term" value="F:magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036068">
        <property type="term" value="P:light-independent chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01047">
        <property type="entry name" value="ACSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01840">
        <property type="entry name" value="AcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008434">
        <property type="entry name" value="AcsF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003251">
        <property type="entry name" value="Rubrerythrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31053">
        <property type="entry name" value="PTHR31053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02915">
        <property type="entry name" value="Rubrerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02029">
        <property type="entry name" value="AcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rubrerythrin" evidence="7">
        <location>
            <begin position="89"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="358" mass="41990" checksum="77E20D1E2EB95A18" modified="2018-01-31" version="1">MVSSISKSDSAGLPSGIKAPVQETLLTPRFYTTNFDAVAQMDLSGQQVELEAVVAELRADYNRHHFVRNDEFNQCWEHIDGETRKAFIDFLERSCTSEFSGFLLFKELSRKLKNRQPLLSEAFNLLARDEARHAGFLNKAMADFGLSLDLRYLTKNRTYTFFPPEWVIYTVYLSEKIGYWRYILVFRHLEQHPEHRIYPLFRYFDSWCQDENRHGDFFKALLRSQPQLWNSWKARLWARFFLLTVFATHTMTVLERSTFYDSIALDPQEYNKQVIHHTNETAKRAFPSVLDTDHPEFFPRLEQCAIANQKLAEISGNGRPAPIQFCQKLPWIVAIVWQLLRLYLLPSIDTEASRTVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2K9</accession>
    <name>A0A2G4F2K9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55982">
        <property type="protein sequence ID" value="PHX55982"/>
        <property type="gene ID" value="CP500_007785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7363" checksum="4621FF555976C775" modified="2018-01-31" version="1">MQFFSTTESPIAHQPYHNFMALLMRLYPQRLGDILHQHFAFSSAMNLSEKLQKVDRLKVWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2L1</accession>
    <name>A0A2G4F2L1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease 3</fullName>
            <ecNumber evidence="6">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribonuclease III</fullName>
            <shortName evidence="6">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rnc</name>
        <name evidence="10" type="ORF">CP500_007605</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56013">
        <property type="protein sequence ID" value="PHX56013"/>
        <property type="gene ID" value="CP500_007605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="9">
        <location>
            <begin position="3"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="8">
        <location>
            <begin position="163"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="237" mass="27016" checksum="7D896842E246BE92" modified="2018-01-31" version="1">MQLTSPTKEIQMTLPEFNNEKLFRQALTHRSYVNENPSYREEDNERLEFIGDALLTFLSGEYLYQRHSEMGEDQMTRRRSALVDEKQLARFAIEIGLDIRMRLGKGAHREGGITNPNLLSSTFEAFIGAYYLDTQDMDKVRKFVRQMFDSVPENVVETRSTVDSKNRFQEWVQANVGTTPPKYVTVQAGGTPHAPEFLAKVCVADKEFGEGKGRSKKDAEKNAAEDALARLKKRGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2R1</accession>
    <name>A0A2G4F2R1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55747">
        <property type="protein sequence ID" value="PHX55747"/>
        <property type="gene ID" value="CP500_009070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027372">
        <property type="entry name" value="Phytase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13449">
        <property type="entry name" value="Phytase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="207"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Phytase-like" evidence="2">
        <location>
            <begin position="598"/>
            <end position="929"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1045" mass="110859" checksum="1B4616335B2AE7E3" modified="2018-01-31" version="1">MAAINGTSGNDTLSGTIAADLISGLGGDDAISGQEGNDRIFGNAGNDLLLGGSGNNALYGGRNRDTLQGGEGDDFLSGDLDRDILTGGGGKDIFAIGRIGTATTGGSQLENADVITDFVKGQDLISVSGISPANIEISRGTGNFSNSIVLKDPGTNQFLAILEGVRNFDSGDFIVAENPVPGVRFSSFNASLNRSSAGRLITDLSTPSNQQAKNVAETIQRVNPDVLLINEFDYDSSNTALNLFQQNYLSVSQNGAIPVNYPFRYTAPSNTGIASGFDLDNNGSTVTEVGTTGYGNDALGFGDFPGQYGMALYSKYPIDTANIRTFQNFLWKDMPGAFLPDDSATVVANDYYSPAELNVFRLSSKSHWDVPININGDIVHALVSHPTPPVFDGPEDRNGKRNHDEIRLWADYITPGKGSYIYDDRRTFGGLVPNASFVIMGDQNADPVDGDSFDNAILQLLNNSRVNTGVTSAIPASLGGIQQVADGGNNVNQKGNPAFDTADFGDAGTGSGNLRVDYVLPSADLPLNDAAVFWPVTSDPLYRLVGDRQTADTTPTSDHSLVWADIAVGDRSPRTSVKNINFLGQAIYPTGSVTVQGTQLGGLSGIDYDQVNNRYYSISDDRSDRNPARFYTLNIDLSSGALSSSGINFSGVTTLLNQNAQPFATNTLDPEGIGLTSNRSVFISSEGEVSPNLGAARVQSPFVNEFALGSGLQLRQLPVPSKFVPVVQDTNNNQIVDTGDTPTAGVRNNLAFENLTITPDGKFLFTATENALVQDGPLATINSGSRSRILKYNLTTGQPEQEFLYVTDPVALPAVPETAFSTNGLVELLALDDRGTFLALERSFSTGAPGTGNTIKLYEVRLNGASDISSINSLNAININTVKPVEKRLVLNFDSLRLPTGFDNVEGMTLGPVLPNGQQSLVLVSDNNFSATQFTQILAFGLALETEIPRRAQSLDILTDGGAIIDSTMSGDNISVETSDNKSAFITDFRTVLDSMGFDTEQNYAIDPTAINRSEVGAVSQPVGQIAAEQNIFSSLPSAFGIGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2U9</accession>
    <name>A0A2G4F2U9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55787">
        <property type="protein sequence ID" value="PHX55787"/>
        <property type="gene ID" value="CP500_008850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="87" mass="9563" checksum="123E8F0DA466C1C7" modified="2018-01-31" version="1">MNQLPNPFNSNPSNPLDPLNQDPDRLDDEDGELPRRYHPATKKTLQKFFIILIVVGAIIGGILSIGVISLMQKAGLTNVPARVENSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F319</accession>
    <name>A0A2G4F319_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_007060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56138">
        <property type="protein sequence ID" value="PHX56138"/>
        <property type="gene ID" value="CP500_007060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="PTHR43078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="3">
        <location>
            <begin position="28"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="345" mass="38495" checksum="CE425DB3D2D27918" modified="2018-01-31" version="1">MVKSLAHDLNHILTHTDGLWEEFREQRIFITGGTGFFGRWLLESFAWANDQLGLKAEAVVLTRNLEAFRKKAPHLVANPAIRFHLGDVKSFEFPEGSFSHVIHGATEASAKLNQEAPLLMLDTIVQGTRQTLEFARHCGAKKFLLTSSGAVYGKQPPDMTHISEDYQGAPDTMNVRSAYGEGKRMAELLCAIYAKQYRIETKIARCFAFVGPYLPLDGDFAIGNFIRDGIQGGKIRVNGDGTPYRSYLYATDLAIWLWKILVKGDVCRPYNVGSDKDITVADLAYTVSSMFDLGLDVLISQEAMPGKPSERYVPSTERATFELQLQALISLEESIKRTIFDSSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F343</accession>
    <name>A0A2G4F343_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_006635</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56180">
        <property type="protein sequence ID" value="PHX56180"/>
        <property type="gene ID" value="CP500_006635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="7">
        <location>
            <begin position="223"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="306" mass="33733" checksum="F42DE732CCA57AC5" modified="2018-01-31" version="1">MRTDNRSEIRKVLIITLLLNLLVMAIKAVVGWLTGSLSLLADALHSVTDSANNILGLVTNHYANPQPDRDHPYGHQKFDAIGALGIAVFLGIACFEILSGAVERLLKGGTVVKISPNQLWILLIVLGINIFVTFYERRVGKRLGSAILVADAQHTMSDVWVTIMVIAGLIGVWQGEVWNIPQLQSLDVFLSFPVAVLVFHSGWKVLTENLPWLVDEMAIAPEIIHAIAIDVPGVINCHSIASRGVVGRQVFIDMHLIVDAVDVETAHRITEEVEAHLEERFNPVRILIHVEPPAYVSDQISYDSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F371</accession>
    <name>A0A2G4F371_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56196">
        <property type="protein sequence ID" value="PHX56196"/>
        <property type="gene ID" value="CP500_006720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="84" mass="9526" checksum="799B5DF546A307EF" modified="2018-01-31" version="1">MNDRSSADLRAVTELHHQLNDLLQQLSPERLQVLADFAAYLANTESEAATQEILAISGLLERVKQNQTTPKTDYTNWRTLRSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3A2</accession>
    <name>A0A2G4F3A2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cobA</name>
        <name evidence="9" type="ORF">CP500_006520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56215">
        <property type="protein sequence ID" value="PHX56215"/>
        <property type="gene ID" value="CP500_006520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="7"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="HEM4" evidence="8">
        <location>
            <begin position="277"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="522" mass="56997" checksum="33497813506646EE" modified="2018-01-31" version="1">MKSQKGKVYLVGAGPGDCDLMTVRSQKLLSQAEVLIYDALIDIPQLELIPVTCLKIEVGKRGGKPSTQQQEINHLLVEHCQRGKQVVRLKSGDPFIFGRSSSEIQALIAADCEFEVIPGISSAFAAPLLAGIPLTDPVMSRCFAVMSAHEPDALEWEALVQIETLVILMGGRNLGEIVWQLQKHGLSSQTPIAIIRDCGRPEQQIWLGTVSDIVHKTTGQSLSPCVIIIGEVVRLREYLMQPEITNGIDIPVTPNHSQLPLAGNTILVTRAATQSGQFSDRLQQQGARVIEMPALVIGPPSTWEALDSAIAQLSSFHWLILTSHNAVDCFFQRLQAKGKDARSLFGIKIAVVGKKTAESLRSHSLQPDFIPPNFVADSLVENFPDNLQNCKILFPRVESGGREVLVKEFTAKGAQVIEAPAYQSCCPETIDPIALAALQNRAVNMITFASSKTIQNFCKLIEQSPELSGSQDWLKNVCIASIGPETSKSCYNLLGKLDVEAKEYTLDGLTEAIVQWVSENQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3C7</accession>
    <name>A0A2G4F3C7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-binding transcriptional activator HetR</fullName>
            <ecNumber evidence="9">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">hetR</name>
        <name evidence="11" type="ORF">CP500_006380</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Might be involved in temporal and/or spatial regulation of nitrogen fixation. Dimerization is required for DNA-binding. Has both a protease and a DNA-binding activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer; disulfide-linked.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase S48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56283">
        <property type="protein sequence ID" value="PHX56283"/>
        <property type="gene ID" value="CP500_006380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043158">
        <property type="term" value="P:heterocyst differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00781">
        <property type="entry name" value="HetR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040949">
        <property type="entry name" value="HetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041936">
        <property type="entry name" value="HetR_DNA-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041935">
        <property type="entry name" value="HetR_flap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005319">
        <property type="entry name" value="Pept_S48_HetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18460">
        <property type="entry name" value="HetR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03574">
        <property type="entry name" value="Peptidase_S48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0010">Activator</keyword>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HetR_C" evidence="10">
        <location>
            <begin position="221"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Interchain" evidence="9">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="300" mass="34990" checksum="9D36E7BAD5568F69" modified="2018-01-31" version="1">MKNDSLDLVKSLSPSAMDQIMLYLAFSAMRTSGHRHGAFLDAAATAAKCAIYMTYMEQDHNLRMTGHLHHIEPKRVKVIVEEVREALTTGKLLKMLGSQEPRYLIQFPYVWLEQYAWLPGRPRIPGNSLTADEKKYLEGKIPPNPPDAQLINSFQFMELIEFLHRRSQEEMSPERRMPLSEALAEHIKRRLIYSGTVTRIDSPWGMPFYALTRATYSPAEQEERTFTMVEDTARYFRLMQDWAQKQPKVMRVMETLDIPPERLDQAVEELDEIIRNWADRYHKRGEPTMIVQMVFGPQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3H7</accession>
    <name>A0A2G4F3H7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_005995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56334">
        <property type="protein sequence ID" value="PHX56334"/>
        <property type="gene ID" value="CP500_005995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037919">
        <property type="entry name" value="OGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366">
        <property type="entry name" value="PTHR44366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="273"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="307"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="527" mass="59470" checksum="8A95A18A083205BE" modified="2018-01-31" version="1">MYLEYEDIRRVSVEITSRCNAACPQCPRTDNQILPAAELKMEDIERIFPKEFCSQLDLIYMCGNYGDAMTSNTTIPAIEYWHRMGVPQVGMYTNGSGRNPDWWQALAKAMTGENDSVTFSIDGLADTNSIYRKNTNWDRIMQSVNAFIQAGGKAVWHYLIFEHNQHQVESARALAEELGFVEFVPKATSRFVAQELFTKQSANQQDHQVENLQVKAKIDRPNQPPTTNLSAPQNQAQRAVELHRQAEDCLKQGQLSEAIAASQQALKIQPNFAPAYKTLGNAVQGLGRMQAAADCYAKALQIQPNFPEVYANVGSLYAQQQQWQPASAYYQKAIELKPNFAGAYRNLAKVLTQLGQPEKANYAWCQAIAIEASQAPEPTQFIPSKPASQQLQPPSLEQYQNPQGEQFMQAVETYGGLNNYYRNVEISCQTQASKDIFISFEGELWPCCWVSHTKYAVYNDTYRPQMLALLEKYGNDFNSLKTQSVKDILKTDWFRQDLTASFSCSKRLDVCAHECGKTFNSTGSQYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3J6</accession>
    <name>A0A2G4F3J6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable endolytic peptidoglycan transglycosylase RlpA</fullName>
            <ecNumber evidence="3">4.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rlpA</name>
        <name evidence="7" type="ORF">CP500_006160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the RlpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56318">
        <property type="protein sequence ID" value="PHX56318"/>
        <property type="gene ID" value="CP500_006160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02071">
        <property type="entry name" value="RlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034718">
        <property type="entry name" value="RlpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012997">
        <property type="entry name" value="RplA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="SSF50685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00413">
        <property type="entry name" value="rlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013976631" description="Probable endolytic peptidoglycan transglycosylase RlpA" evidence="3">
        <location>
            <begin position="27"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="DPBB_1" evidence="6">
        <location>
            <begin position="244"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="109"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="345" mass="37283" checksum="3CDFEB47E6BB26A5" modified="2018-01-31" version="1" precursor="true">MKEKFVGSLLAVLLVPALGTASSCHAQATDASGPNFQGNKQVVFTQQSPQLKVTRVEAEKVGQYQYQARADIESNSIAKIQSHELEGRQAATVYLRNIPVITFLDESPETNTKIGKTDTKASKPSDSKKSSNSNNSETDPVWRASSLAARLNQLARNNVDPNSITVKWEKGDRYLIQANGEELVDINAKTILPDTTSDFSRDALQVTNRLRRLLGNAAPLGEILGKPQPERPVLSIGSVQVRINGWASWYGPGFDGNLSASGERFNQNALTAAHRNLPFGTLVMVKNLDNGRTVVVRINDRGPYVGNRVIDLSAGAASVLGMMSSGVARVEIEVMAPNSAETVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3W6</accession>
    <name>A0A2G4F3W6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molecular chaperone DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56439">
        <property type="protein sequence ID" value="PHX56439"/>
        <property type="gene ID" value="CP500_005400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021788">
        <property type="entry name" value="CPP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33372">
        <property type="entry name" value="PTHR33372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11833">
        <property type="entry name" value="CPP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="22638" checksum="D02415DADBEA753A" modified="2018-01-31" version="1">MSDSTPYQLLEVDENASFDEVQEARTRLAEHYSNDRKRLESIEAAYDAILMDRLRQRQEGKIKVPERIRFPERLSPPTTSFTPSAPSGSPAWLQRLIDTPSRSDILWPAGIYAGLGGLSIYPAANNSLLQLTLALGVGSCLYFLNRKEQKFGRALLLTLLALVFGLLLGGLLTSAVNPAFITTEKFIALFTFLTLWLVSSFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3X7</accession>
    <name>A0A2G4F3X7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56449">
        <property type="protein sequence ID" value="PHX56449"/>
        <property type="gene ID" value="CP500_005455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="16127" checksum="315FF387320927A0" modified="2018-01-31" version="1">MKSQTSALKQNVSQKWAITLCYEEQEKLEPRVAQIIEYLAQNCDLPNQWIIADIDATGRCGDQLTKKGNNEEVLRLSSADLLSVLKEEGQVIELDARLVQNGHEVFKILIRDGVSVDVLGSGDVMPLTVLGKYVTVDKSFFLWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F448</accession>
    <name>A0A2G4F448_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56518">
        <property type="protein sequence ID" value="PHX56518"/>
        <property type="gene ID" value="CP500_005030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041479">
        <property type="entry name" value="TetR_CgmR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17937">
        <property type="entry name" value="TetR_C_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="20848" checksum="BBE91C35B9265A47" modified="2018-01-31" version="1">MAEALEIGKRSRSATRESLLNAAGEVVLRSGADALTLDAVAKEAGVSKGGLLYHFPNKEALLTSMVANLITEFEQLLELELTREGDLTAKGAWLRAYIRAGDLFDRQNAAIQSGLLAAVAKDRKLLQPYQEASTRWYQQACNCGVAPLKAGVILLAADGLSWNQLLGLNCISDEDRSHLIWELIRMTYADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F472</accession>
    <name>A0A2G4F472_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PIN_12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56511">
        <property type="protein sequence ID" value="PHX56511"/>
        <property type="gene ID" value="CP500_004970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032557">
        <property type="entry name" value="DUF4935"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16289">
        <property type="entry name" value="PIN_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN_12" evidence="1">
        <location>
            <begin position="21"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="196" mass="22484" checksum="3AC0852802FBD820" modified="2018-01-31" version="1">MSIATGRDPEASTLLMQTPASVQLTIPSICYMESFSALEDEVKRNNYFKQQIDNQISEANRDFTSHHARSLSFNLGQSRNDHERRLQDIKLRLRESIEQLSQNGQMIALTANIIQKSLNATIITKDPTDNLILHCILNHARLHPTETKVFLSGNIKEFRQLPEVQDALQQAGVAKYFSRTEDFLGWLQSQSFDFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F498</accession>
    <name>A0A2G4F498_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">O-linked N-acetylglucosamine transferase, SPINDLY family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56565">
        <property type="protein sequence ID" value="PHX56565"/>
        <property type="gene ID" value="CP500_004780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_41" evidence="1">
        <location>
            <begin position="361"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_41" evidence="1">
        <location>
            <begin position="542"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="745" mass="86144" checksum="96BDD8C914806EF4" modified="2018-01-31" version="1">MISSDSFVAGWQQQAEKYISSENYYQAAKIYEEAIFQEPNVNSYYWHLGLIFLLQGQESEAQTTWLIGMADGESEDIEKWTKELIEVLETEAERRRLQGTKEQDYCIAWAIRQHIREINPEGVNNLLHLIGLSTLLKTYKGEILNELHILELLNSEVVEVDTELLIQVLKNVLDLAPFHPSSFDFAETALVYVKDNTSILEQFLYSFVYKLCYSFKRADVAARFTELGLKFLPKHRKFLYALASFYQDSREYTKGIEAAKLYYSLQENLVNKIDGNLLIMRGLMGAGGYWNEVCLAFELQKSLLASLIDEQNNDLWGASPLGLFNSIFFFPYLQDRLEENLKIRSQIASLAQSQIETSLKEKVDLCRQWKSRLIKTDVSTRRLKIGYISHCLWNHSVGWLARWVFQYHDRERFEINGYFMGYQENYNSLQEWFVGQVSKACKLELSGQEAAQKIYEDEIDILIDLDSLTLTNTCEAIAMKPAPIQVTWLGWDASEIPAVDYFIADPYVLPESAQDYYTEKIWRLPQTYIAVDGFEVGVPTLRRDQLDIPPDAVIYFTGQKGYKYHPDTAKLQMQIIKGVPNSYFLVKGVANQESLKNFFIQIAESEGVRAERLRFLPSAPSEEVHRANLGIADVVLDTYPYNGATTTMETLWMGVPIVTRVGQQFAARNSYTMMMNAGISEGIAWTDEEYIEWGIRLGKDPVLRQQISWKLRQSRQTAPLWNGKQFTREIEKAYEQMWQIYLDKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4B9</accession>
    <name>A0A2G4F4B9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bifunctional protein PyrR</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="4">Pyrimidine operon regulatory protein</fullName>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="4">Uracil phosphoribosyltransferase</fullName>
                <shortName evidence="4">UPRTase</shortName>
                <ecNumber evidence="4">2.4.2.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrR</name>
        <name evidence="6" type="ORF">CP500_004285</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:13017"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56634">
        <property type="protein sequence ID" value="PHX56634"/>
        <property type="gene ID" value="CP500_004285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01219">
        <property type="entry name" value="PyrR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023050">
        <property type="entry name" value="PyrR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="15"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="PRPP-binding" evidence="4">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="19638" checksum="233F466EFC057316" modified="2018-01-31" version="1">MTKIIEILSPDEVRRTLTRIASQIVEKSGDPGELVLLGIHTRGVPLAQILAAQIEVLEQVKVSVGALDITFYRDDLDRVALRTPAKTEIPFDLTGKTVVLVDDVIYKGRTIRAALNAVNDYGRPEKIWLAVLVDRGHREVPIQPDFTGKKLPTAKEEQVKVYVFDVDGRDGVELIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Z3</accession>
    <name>A0A2G4F4Z3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56808">
        <property type="protein sequence ID" value="PHX56808"/>
        <property type="gene ID" value="CP500_003530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="15744" checksum="DBD4785F3064BAC8" modified="2018-01-31" version="1">MDTQHKLQQHNSTEAVQTVSLYRFEEPQKWPRSLTMQIPIIFDGRFKDSLANVSQAIKLMSKYFGGSRIWFELGTYIDQKGHLAFDLNVWVKSQMDEEKFSYYCPKVRDLACQIRDKLRQEAIVLETDGDMECL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F537</accession>
    <name>A0A2G4F537_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56831">
        <property type="protein sequence ID" value="PHX56831"/>
        <property type="gene ID" value="CP500_003270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="716"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1002" mass="112805" checksum="B839E0A1B5A4E3D7" modified="2018-01-31" version="1">MARKRFTFFGSIQVLFLRPVRQRFRRSLRLFTILFVVGFIAFFAVNVKAQSIAVNSQQLTVNSQHHSGKTGIGNESRSPQAWENLARTSYAAGEFAEAAKYWRQAVAGFEVGGDWLNQAIALSNLSLTYQQLGRWEEANSAIGKSRSLLPQESRVKSLVELKAIGQILDIQSNGEWEQGQINLALQTGKQATNIYVKLKDNLGWKRSLIAQVKTLQELGLYQQACQAIIPVVESNNSENFVIPSQDCQQLITEKLVTIKRSVKTPSNPTLKNIQITGARLLGDVWRQLGYLKESQQLLEELERVVTQQEFPQEQALVLLSLGDTYQSLGNRNKFLSVSEDNNYKKDYENAINLYKKSINVTANNSFLKVQAQLNLLSLVVKRKSEFTGNAKEIQQLRLEILSQLSKLPRSHKLVYAEVSLMNSLVDLKKQLETPNNVSNSSNVNSEKILNYCLPNSAIVAESVLENIEFVSSGEVGRLGAKAIALARNLGDFRATAYALGNLGTVYEKNQQWLEAQQCTEQALLLSQNVQLNAPDLAYQWQWQLGRIRRNGEAKDVDGAIGAYTAAFNTLQSLRNDLVPISRDGQFDFRDKIEPVYREFVDLLLQGEKPSPENLKQARNVIEALQVAELDNFFRDGCVVVNKAEEIDAIADKYDPTAAVIHAIILPNRLAIILKLPGQSELEYHVTAVSEETIRNTLKKLGGYLEERGKNPDVIITAKQLYQWVFKPIELSIDKNLNVETLVFVLDRPLQKIPMTILHDGKQHLIQKKYDIVLAPGLQLTNAKERQDTRFKDIKLFAGGVDEKQLPIEDVEFEAIKNLKEEINGIDKVMPVKKRLLNSEFTIAKIRQLIALENYSIIHIKTHGQFSSQPEKTFLVAYRSFLRSKDLDNLVKTGSEGDRHTIELLVLSACQTAKGDDRATLGLAGLAVRSGARSTLSTLWKADDEATTKLMVHFYNELRKPGMKMARALHTAQKILIEQDGYKDARTWANYVLIGNWLPLISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F538</accession>
    <name>A0A2G4F538_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56870">
        <property type="protein sequence ID" value="PHX56870"/>
        <property type="gene ID" value="CP500_003075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="42"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="182" mass="20542" checksum="75678CA86C611048" modified="2018-01-31" version="1">MAIGQELPQLLKQRLFYQGRKFNFDVNTLRLPNGSEGEWECIRHPGGALAVPVTPEGKLVLVRQYRFAAKGRILEFPAGTVEINETPAETIKREIEEETGYRAGKWQRLGEFLLAPGYSDEIIYAFLAQDLEKLEKPPAQDDDEDMETVLFTPEELEKAILAGEPIDAKSIASFFLARPFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F575</accession>
    <name>A0A2G4F575_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdopterin synthase sulfur carrier subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_003185</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MoaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56889">
        <property type="protein sequence ID" value="PHX56889"/>
        <property type="gene ID" value="CP500_003185"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044672">
        <property type="entry name" value="MOCS2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359">
        <property type="entry name" value="PTHR33359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="9429" checksum="0A738D6A84AD6C6D" modified="2018-01-31" version="1">MSNSLITITVKLFAAFSEAYGVSELTLEFPLLTPVSQVLERAIAQHPQLEQWRSVTRFGLNLEFVSPDTILQDGDEVVLIPPVSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5C2</accession>
    <name>A0A2G4F5C2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56984">
        <property type="protein sequence ID" value="PHX56984"/>
        <property type="gene ID" value="CP500_002545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029471">
        <property type="entry name" value="HNH_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14279">
        <property type="entry name" value="HNH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH_5" evidence="1">
        <location>
            <begin position="22"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="378" mass="42700" checksum="EFEF18FCB2FCF404" modified="2018-01-31" version="1">MAAPKSPSSGAFNNTFSKISECYICNKNIVPKEIYNEHIILNSLGGRLKSKSLICRQCASKLDKIDAALSRSLNSFGLLLNIPRDRGTNPPILATRTDTGERISLDSGGKPVVIKPIITDKLADKEQPSLYISAKDKPQMREILTGLKRKYPLLNVEELVNSAVARQEDIPPVIINLSFGEEEFRSVCKMAINFYMYHDGERDLISHLIPYIKDGCENQYVGYYYPDELIAASNSSESFIHTLYIEGNPQEKILYGYIELYSAFRLIILLSDSYEGDFFQKVYSFNVLSREEMEKEININVSRKEILNLVNNPEPPLKKIESAIKVLVDAIKLNQINKAINKDIEDFSQNIPEGTIVDGKMLQELFSKLKLSKTIFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5D2</accession>
    <name>A0A2G4F5D2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nitrate reductase associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56982">
        <property type="protein sequence ID" value="PHX56982"/>
        <property type="gene ID" value="CP500_002535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013481">
        <property type="entry name" value="CHP02664_NO3_red"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09655">
        <property type="entry name" value="Nitr_red_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02664">
        <property type="entry name" value="nitr_red_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="149" mass="17031" checksum="62051D4AA52D2EFE" modified="2018-01-31" version="1">MFFKFEADFVEALRCIPMQVRLKLDTCGIKLKLQDWNHFTQAERQTLVELPCLTSPEILHYREQLNQILIQHTGKSGTDLAIDPNPPWLDAATIPESVTAKAQEFDVTITLAQWMALGAIERFALIKLSRSSHENKNFLPAVREFHLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5G7</accession>
    <name>A0A2G4F5G7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="10">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 14" type="primary">atpA</name>
        <name evidence="14" type="ORF">CP500_002495</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cellular thylakoid membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56975">
        <property type="protein sequence ID" value="PHX56975"/>
        <property type="gene ID" value="CP500_002495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0139">CF(1)</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="13">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="11">
        <location>
            <begin position="150"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="12">
        <location>
            <begin position="372"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="170"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="10">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX56975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="506" mass="54448" checksum="054A02F326B98C1B" modified="2018-01-31" version="1">MAAIRPDEISNIIRQQIEQYDQDVKTSNVGTVLQVGDGIARIYGLDKAMSGELLEFADGTVGIALNLEEDNVGAVLMGQGLGIEEGSAVIATGRIAEVPVGEAMLGRVVDALARPIDGKGEIKTTETRLIESPAPGIVARRSVYEPMQTGITAIDAMIPVGRGQRELIIGDRQTGKTAIAIDTIINQKSENVICVYVAIGQKASTVANIVNVLQEKGAMDYTIVVAANASDPATLQYLAPYTGASLAEYFMYKGKHTLVIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGEGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSSDLFNAGLRPAVNPGISVSRVGSAAQTKAMKKVAGKVKLELAQFEELAAFSQFASDLDKATQNQLARGQRLRELLKQAQSSPLPMNEQVAIIYAGINGYMDEIPVDQVSKFTVGLRDYLRTSKPKYGEIVQGGAKALTDEAEKLLKEGITEFKQSFLVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5N8</accession>
    <name>A0A2G4F5N8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57080">
        <property type="protein sequence ID" value="PHX57080"/>
        <property type="gene ID" value="CP500_002030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="236"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="466" mass="51484" checksum="5522EC147A3584F4" modified="2018-01-31" version="1">MKTKIGQGIKSDFFWWWLLIAVPVVGVLVINLPPNLRFIADKFSEKSPANLDANYRYHFSDFLRNNPNQKDAIQQEISFYQQRLAVDAKSGLNRAALAGVYLKMGRATGEGGWFLLAEQAAQRSIADLPFNNNGALLVLARIAEARHDFVTALRLAKQVGFDNEDAIALSVTSHLAMGKVSEANAAAETLVNRLPSLGSLTLRALARESQGRDAEVLQDYQQALALEEPGEVAGSARTRSLLGRFYSRRGQFVQAKALFLETLRLLPRYPLALIYVADLEVRSGNYREAESYYSKVSAYSGGAATVYDRIVDRGMARVKELQGDAIASRKLLDKAEAGLRQEQVSGVGGFGHRRDLASLLLEKGRSQDVAEALALMQQEVKIRRDAVTLDTLAWALSSAGEWQKADDVMAEIVRSGIRDAAMFDRAGAIAHKLGKNTESRAYFQTAKEIDPNLKMRSGHSILDFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5P3</accession>
    <name>A0A2G4F5P3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57045">
        <property type="protein sequence ID" value="PHX57045"/>
        <property type="gene ID" value="CP500_002335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="7924" checksum="6177D3C9FC892074" modified="2018-01-31" version="1">MNITVKGKIERQGFGPGTWALVGEDGETYELKDASSELKKEGLKVSVKGLVRKDIMTFAMIGPVLEVQSVEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5S2</accession>
    <name>A0A2G4F5S2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57110">
        <property type="protein sequence ID" value="PHX57110"/>
        <property type="gene ID" value="CP500_001525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="39"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12983" checksum="B3673C56D15D50B9" modified="2018-01-31" version="1">MEINTKDYSILYDSATETITCCGSFRLSQMEEYAPIVQLLNDVSEVAPKTITLDLRKLEFLNSSGINILSKFVIKVRQQKSIQIAVKGSKQIPWQGKSLKNLQRLMPSLYLELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Z9</accession>
    <name>A0A2G4F5Z9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57169">
        <property type="protein sequence ID" value="PHX57169"/>
        <property type="gene ID" value="CP500_001655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12278" checksum="250FB0D55218CA2A" modified="2018-01-31" version="1">MDAEARKKLSEVVKLARGDLSFSAFGRLLGVSGSAVQYWEKGQVLPDTKNLTQIAAKAGFTMEELMAHLEGKPMPEPVNTNELLKKIQCMPMSELAVIGRAVMDRLAAAAESSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F641</accession>
    <name>A0A2G4F641_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PAS domain-containing sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_001295</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57218">
        <property type="protein sequence ID" value="PHX57218"/>
        <property type="gene ID" value="CP500_001295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="560"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="521"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="823" mass="90647" checksum="3F4A2A008D001FD1" modified="2018-01-31" version="1">MNRDPVSIPALPRSLSSPETWGFGFSGLLLWLGTAPGMNAALGPQAIWVWLPGTIIGMMLNLQVKRLGTYFPDVAGGTPNYTTRLLHHFPNLARYGAIGYLLGWISVPPMNAIILTDLIKVNLAPLGITCPETLLRIGFTVLPFIVAFSGTRTLGILHSFFVFPAIGFLLTFCLQGIAWLSLTPASPGLLPDLGVGISAMDWMKWFFIAVYAVYGGESASAFVADSYQPRVTLRCLQVMTGLIPIVYLGGSWVLMRLATDPGLGDSAYLHLVAATQPFWGTFAPALVTFLIASGCLLSSATAVSVSPRILYQLAKDRYLPPVFAVLSPRGVLEPSLIFTLGLSLICLGWGDVARVVMVTGTGYLSSMMAIHLGEWVGRRRPEARWPWWSLGFFGMEATVLVVGGLAWGYQDLAIGLLLPWLIGMAGTRLPRLNFSLFHPDGWMQRYQRYHRQSHTGTTDWLAFQVTILIGLVCSALSIGWWVRAGLDRVGVGQYVALFSILLVTVAYVGVAIACWTSLPQIAAINEAREQVERTLLELQQAQMQLVQAEKMSSLGQLVAGVAHEINNPVNFIHGNLRPLREYTQNLMALIELYQQQNPNTSPDIQAMVDDIDLEFLQTDLPKILDSMKMGTDRIRQIVLSLRNFSRLEEADLKTVDIHEGIDSTLLILGHRLKAKGDFPEIKVIKDYNLLLPYAECYPGPLNQVLMNILANAIDALEESGSEKTYEQLEANPGEIRIRTSPIDAEWIEIAIADNGVGMSEQIQQRIFDPFFTTKPVGKGTGMGMSISYQIITEKHGGKLKCFSTIGKGTEFVIQIPLRQQVIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F676</accession>
    <name>A0A2G4F676_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lgt</name>
        <name evidence="3" type="ORF">CP500_001060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57260">
        <property type="protein sequence ID" value="PHX57260"/>
        <property type="gene ID" value="CP500_001060"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01311">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="33227" checksum="19CBC327531A79E3" modified="2018-01-31" version="1">MVLNIFTLPIGFQFTSPGPIIFQLGPLAVRWYGLLIASAVLIGVSLSQYLAAKRRVNPELLGDLAIWLVVGAIPCARIYYVAFEWQQYAQRPEDIMAIWKGGIAIHGAMLGGAMAALIFAKIQQVSFWKLADLVAPSAILGQAIGRWGNFFNSEAFGRPTDLPWKLYIPLEHRPQPYANFEYFHPTFLYESLWNLTVFGLLLTLFFSDLQGKIRLKIGSLFLVYLTAYSSGRVWIEGLRTDSLMFGPLRTAQMVSLTGIVLGLGGLAWLYYFDRALPDVVSPKCDRAELPQQSPEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6B4</accession>
    <name>A0A2G4F6B4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57333">
        <property type="protein sequence ID" value="PHX57333"/>
        <property type="gene ID" value="CP500_000705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="12144" checksum="C0F1E0394961A389" modified="2018-01-31" version="1">MSKQSVITKYIEITPGVLGGKPRIAGHRISVAHIAEMYLNMGESIEEIARDYNLLPAAVHAAMTYYYDHREEIDRRTAESDAFVEELKRKSPPSRLQEKLREIRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6J2</accession>
    <name>A0A2G4F6J2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57392">
        <property type="protein sequence ID" value="PHX57392"/>
        <property type="gene ID" value="CP500_000170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="187" mass="21607" checksum="403C9192F7E292AE" modified="2018-01-31" version="1">MVALPDRPLMSAEEYLAWEPTQEERYEYWDGEVVAMSGGTRNHNRITFNFSKLLDDALVDRPCEMYMADVKAQVQRGQKYFYPDVVVTCDDRDNDPQLVQFPSLIIEVLSPSTEAIDRGTKFAKYRQFSTLKEYVLVQVEQPGVEVFRRNEKGQWVLSEYSLGDSLKLESVGVEIAIADLYRQIQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Q5</accession>
    <name>A0A2G4F6Q5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-phytyl-1,4-naphtoquinone methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.329</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Demethylphylloquinone methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">menG</name>
        <name evidence="5" type="ORF">CP500_000095</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Methyltransferase required for the conversion of 2-phytyl-1,4-beta-naphthoquinol to phylloquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>demethylphylloquinol + S-adenosyl-L-methionine = H(+) + phylloquinol + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:40551"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28433"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:87844"/>
            <dbReference type="EC" id="2.1.1.329"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; phylloquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.329" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57381">
        <property type="protein sequence ID" value="PHX57381"/>
        <property type="gene ID" value="CP500_000095"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00995"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052624">
        <property type="term" value="F:2-phytyl-1,4-naphthoquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042372">
        <property type="term" value="P:phylloquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01982">
        <property type="entry name" value="MenG_phylloquinone_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01813">
        <property type="entry name" value="MenG_UbiE_methyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032904">
        <property type="entry name" value="MenG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01934">
        <property type="entry name" value="MenG_MenH_UbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01183">
        <property type="entry name" value="UBIE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="233" mass="25619" checksum="B0F7D333183EF879" modified="2018-01-31" version="1">MTNNSEKIKTIFNRIAPVYNQMNDWLSLGQHRVWKQMAVKWSNASPGNTCLDLCCGSGDLALLLSQQAGPSGSVFGVDFSQEQLAVAGRRDRPFLTPSSPISWVEADALDLPFPDNYFDCATMGYGLRNVTDIPRSLQELHRVLKPGAKAAILDLHRPNNSLMLSFQQFYLESLVVPIAQQFGMTQEYAYINPSLAKFPIGPEQVAIALQAGFTTATHYPIAGAMMGVLVISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6S4</accession>
    <name>A0A2G4F6S4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57197">
        <property type="protein sequence ID" value="PHX57197"/>
        <property type="gene ID" value="CP500_001350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="21"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="378" mass="43111" checksum="9368E5598E006D72" modified="2018-01-31" version="1">MLESFQIHNFRLFKHLEVRKLGRVNLIVGKNNSGKSTFLEALELYTSNASAIVLLDLLKSRQETWFSEAQPHSQNFISNSVRHLFHGHKLPPIGEQGISLGEVASNIKLHISAAAYQDKNDDEGTLRKIRISDRELDGNLSNVEVFLVAEEGERTRRIFSLDNKDMRDNRNRMISVSERQQSEFKYTWQIVSTENMPNRKLAALWDLTSLTDLESEVISALGLIDDRVTGVAFVENSGNDFRTRENGQRIALVKIKGIDEPLPLKSMGDGMTRLFHIIVALVNARNGLLLIDEFENGLHWSVQPKVWDIVFQLSDRLNVQVFATTHSRDCIKGFYQAWNNYPTLGAFFRLDEKNGLIKATEYTSETLNDSIDMDVEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUE0</accession>
    <name>A0A2G4EUE0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutaredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">grxC</name>
        <name evidence="5" type="ORF">CP500_022975</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000255">
        <property type="protein sequence ID" value="PHX53163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53163">
        <property type="protein sequence ID" value="PHX53163"/>
        <property type="gene ID" value="CP500_022975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03418">
        <property type="entry name" value="GRX_GRXb_1_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011900">
        <property type="entry name" value="GRX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02181">
        <property type="entry name" value="GRX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="4">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="9522" checksum="FADA7B17A4E2AFE1" modified="2018-01-31" version="1">MAPKVEIYTWRTCPFCIRAKALLKRKGVEFTEYAIDGDEAARAKMSDRANGGRSLPQIFINDQHIGGCDDMHELDAIGNLDPLLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUK2</accession>
    <name>A0A2G4EUK2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4363 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000253">
        <property type="protein sequence ID" value="PHX53168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53168">
        <property type="protein sequence ID" value="PHX53168"/>
        <property type="gene ID" value="CP500_022930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013955574" evidence="2">
        <location>
            <begin position="20"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="142" mass="15468" checksum="83CB006C0F54AD4C" modified="2018-01-31" version="1">MARFNQILVLGALSLLTLAGCDIFQEDSTPKTSSSAVPGTGVKTDKATTPLKYPELSGLVFYTKKAVEADNFPKAKTEFGKFENAWKKVENGMKTKAPTGYNAVKEATAKVTTEFKKSEPSKDKVLAQLDLLDKTIKTFPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUL6</accession>
    <name>A0A2G4EUL6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000236">
        <property type="protein sequence ID" value="PHX53225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53225">
        <property type="protein sequence ID" value="PHX53225"/>
        <property type="gene ID" value="CP500_022615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7429" checksum="B520925F9848EDAE" modified="2018-01-31" version="1" fragment="single">MASIIDSGLGLTILDFSSSPVRDGCLTIKSRSPLAPGLFHSHQKSQMMGRVGEKERGRRGIGGMTEKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUN3</accession>
    <name>A0A2G4EUN3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anhydro-N-acetylmuramic acid kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000252">
        <property type="protein sequence ID" value="PHX53176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53176">
        <property type="protein sequence ID" value="PHX53176"/>
        <property type="gene ID" value="CP500_022920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006040">
        <property type="term" value="P:amino sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005338">
        <property type="entry name" value="Anhydro_N_Ac-Mur_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30605">
        <property type="entry name" value="PTHR30605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03702">
        <property type="entry name" value="AnmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="306" mass="32498" checksum="23990E9ECB8228C3" modified="2018-01-31" version="1" fragment="single">GERGGEGDGERGRFSADSSPIPSADMGYSLQLGRGALIAALTGITTVSNFRAADIAAGGQGAPLVPIVDAYLLAEPDRHLCIQNLGGIGNLTYLPAQKNSPLVNKSQVSHVGDGILGWDTGPANSLLDLAVQHFSGGTKTCDENGDWAAQGTPCQALVADWLQQEFFLEKPPKSTGRELFGVDYFNRCLVEASDYNLSPADVLATLTELTVASIAHSYQTFLPQMPDRVLLCGGGSHNLYLKRRLQALLHPVEVLTTSEEGLSVDFKEAIAFAVLAEWRVRGIPGNLPQVTGAIAPVLLGEINSCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUN4</accession>
    <name>A0A2G4EUN4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Valine--pyruvate transaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000246">
        <property type="protein sequence ID" value="PHX53198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53198">
        <property type="protein sequence ID" value="PHX53198"/>
        <property type="gene ID" value="CP500_022790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="202"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="440" mass="48863" checksum="41CFBD9482C5D698" modified="2018-01-31" version="1">MKPALTQFGTQMSQLTGVRAIMKDIIETLRAGSGQEFINLSAGNPVILPEVEQLWRDCTAELLASAEYGEVVCRYGSSQGYQPLIDAVRMDFNRRYGLNLTDRNILITPGSQSIYFYAANAFGGYTAPQQEIDKQAEVFNPKSKIQNLKSIVLPLSPDYTGYGGVSLIPEAVVACKPTLDIDEAAHRFKYRPDFSQLSIDQTTGCVIFSRPCNPTGNVLSDDEVKKIAAMASAFDVPVFIDSAYGPPFPALNFTEMTPIFGGNIIHCMSLSKAGLPGERIGIAIGDEQIIQVLESFQTNMCIHSPRYGQAIAARAINSGALADIGINVIRPYYQSKFDVVETTLEQAMPKDLPWFLHRGEGAIFAWLWLKDLPMTDWEFYQELKQVGVILVPGSSFFPGLREDWRHKQECLRISLTATNQEIETAMKRLAQMVEKVYQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVE5</accession>
    <name>A0A2G4EVE5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Site-specific integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_023050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000262">
        <property type="protein sequence ID" value="PHX53147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53147">
        <property type="protein sequence ID" value="PHX53147"/>
        <property type="gene ID" value="CP500_023050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="105"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="299" mass="34225" checksum="78A5849A17A21849" modified="2018-01-31" version="1">MRLTDTVVQIQICQKKLVALTTQKGIWPEVDRALNAVSPDCLEFTASSASLLLAELLDRYATTTTRKVLENVRAANLWGIEEELISKNFYSRLFKSIPKSQKSSRSRKCFEKHEIEQILEAFASNEFCSKFSVRSHSHYYGYVNFLALTGFRPEEAITLTWSDINNKNEIVVSKAYSQGILKSTKTYETRRFPVNSQLDKLLKTLPRTQSLIFPSAEGGYINQHNFGERYWKPIVKGLAAIRKIEEYLPTNNLRHSWITRMLRSGLDIATVAKLVGNNSDTIMKHYFAAKTQDLVLPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVL3</accession>
    <name>A0A2G4EVL3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TldD/PmbA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_021040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000184">
        <property type="protein sequence ID" value="PHX53518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53518">
        <property type="protein sequence ID" value="PHX53518"/>
        <property type="gene ID" value="CP500_021040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025502">
        <property type="entry name" value="TldD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004919">
        <property type="entry name" value="TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="3">
        <location>
            <begin position="20"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="5">
        <location>
            <begin position="108"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="4">
        <location>
            <begin position="223"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="455" mass="49205" checksum="655293815A7ECB9F" modified="2018-01-31" version="1">MQEQLMEAIAPYRDRVDYLEVRLEQSESTAISFRGAQLDAVNRSFSLAGGIRACHKGGWSFVTFNSLAELKDRIEEAVVQSRLVGSEKTVLADVNPVQDYVAVELGRDPRSITLAQKRKLLESYNQLLLDYDPRIQTTMAGYSDRFGITYFVNSQGTSIAQERLDVTGRFGAIARGDGGIVRQGFESIHSRSDYDVLTNIEDRVKGAAVRALGQLEAKSVKGGQYPVILDPYLSGVFIHEAFGHLSEADGIYENPKMQELLTLGKPVAIAQLNVIDDATVPGLPGTLKYDDEGVPAQCKHLIKNGVLATRMHNRETAGKMGESPTGNARALSATFMPLVRMTNTALESGENSFDEMIGDIEEGVYAVRMLGGQTNGEMFTFAAAQGNMIRDGKLAEPVSDVTLSGNVFQTLKDIEAIGNDSVYAYGGCGKGGQSGLPVSVGGPHLRIKNVVVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVM5</accession>
    <name>A0A2G4EVM5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53584">
        <property type="protein sequence ID" value="PHX53584"/>
        <property type="gene ID" value="CP500_020800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="142" mass="16552" checksum="D7C3D0D944B79602" modified="2018-01-31" version="1">MTPTLFGRWQTRILLFATVGILVTLPFFLGLISSKSGSIFFWILGYIAIFGIGWDILYIYIQHFRWDRDWPGAFQLLAGIWEAVFVLFLIKIVGLPGISDQDFELGAFALHYSFVWLAIYLASQTLMRILFPYWRFRGGQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVN9</accession>
    <name>A0A2G4EVN9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000173">
        <property type="protein sequence ID" value="PHX53612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53612">
        <property type="protein sequence ID" value="PHX53612"/>
        <property type="gene ID" value="CP500_020600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007516">
        <property type="entry name" value="Co_F420_Hydgase/DH_bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045220">
        <property type="entry name" value="FRHB/FDHB/HCAR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007525">
        <property type="entry name" value="FrhB_FdhB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31332">
        <property type="entry name" value="PTHR31332"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04432">
        <property type="entry name" value="FrhB_FdhB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04422">
        <property type="entry name" value="FrhB_FdhB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FrhB_FdhB_N" evidence="1">
        <location>
            <begin position="80"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="FrhB_FdhB_C" evidence="2">
        <location>
            <begin position="164"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="405" mass="45726" checksum="0095A72BAF0F825A" modified="2018-01-31" version="1">MTATDSAKHQKSKALKPGSRRPAKELCSECGLCDTYYIHYVKESCAFLTQHIAELEAEIHGRSRNLDNPDDWYFGVSQNMMAARKKEPIEGAQWTGIVSTIAIEMLEKGIVEGVVCVQNTKEDRFQPMPIIAKTREEILAAKVNKPTLSPNLSVLEQIEKSGMKRLLVIGVGCQIQALRTVEKKLGLEKLYVLGTPCVDNVSRAGLQKFLDTTSRSPETVMSYEFMQDFNVHFKHEDGSTEKVPFFGLNTKELKDVFAPSCLSCFDYVNSLADLVVGYMGAPFGWQWIVVRNDTGQEMLDLVTDQLNTQPVMSQGNRKEAVQQSIPAYEKGVTLPMWAAKLMGVFIERIGPKGLEYARFSIDSHFTRNYLYVKRNYPEKLEAHVPEYAKRIVGQYKLPEVYSNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVZ3</accession>
    <name>A0A2G4EVZ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53722">
        <property type="protein sequence ID" value="PHX53722"/>
        <property type="gene ID" value="CP500_020010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="223" mass="25426" checksum="DC5AEADFC772ED25" modified="2018-01-31" version="1">MTVTTINPSAEKTTQLVVLSNISWQTYKSLLAEAGDKRSSRFSYSQGVLEIIMPSDLHETINCLLKRIVTALTEELDLKIKGFGSTTLNREDLEQGAEPDSCFYIQNVDRILGKRLDISTDPPPDLVIEVDITSPSSNRFVVYTQLGIPEVWRYRSQTVQIYQLQNREYISCDRSPTFPILSVAMLNQLLQMAETQDDHAIIRSLCQWVREQLRSPENQQSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW10</accession>
    <name>A0A2G4EW10_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA interferase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Toxic component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PemK/MazF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000168">
        <property type="protein sequence ID" value="PHX53646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53646">
        <property type="protein sequence ID" value="PHX53646"/>
        <property type="gene ID" value="CP500_020420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR033490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="13097" checksum="4EFF4DD9A6AF6C19" modified="2018-01-31" version="1">MLGDIYLADLNPSRGSEQAGIRPVIIVQRDTLDRFTTTVVVIPVTSNLRRSKIPGTIILPTGEGGLTQESVVLCYQVVAIDRERLIKKLGTLSAHYISRLQVALQYTLQMDESENVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW11</accession>
    <name>A0A2G4EW11_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000168">
        <property type="protein sequence ID" value="PHX53640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53640">
        <property type="protein sequence ID" value="PHX53640"/>
        <property type="gene ID" value="CP500_020385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013854984" evidence="1">
        <location>
            <begin position="26"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="12744" checksum="587F8194AF598309" modified="2018-01-31" version="1">MNKLLLTLLVSPTLFGSVMSLSAIANPVQPSQTPGQPTNSPRCVQSPHTQRLTCIRLPGKSAAVNSQAKISWQRQGDEPIAMLDFTEEESDAAVALFGCDCPLCLNSLRQLRGLPPLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW12</accession>
    <name>A0A2G4EW12_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53709">
        <property type="protein sequence ID" value="PHX53709"/>
        <property type="gene ID" value="CP500_020120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006637">
        <property type="entry name" value="ChW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07538">
        <property type="entry name" value="ChW"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00728">
        <property type="entry name" value="ChW"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="580" mass="62309" checksum="B7561D1E4D08AA21" modified="2018-01-31" version="1">MEPTHKDLLQQIAGLSETYPNLADRLAQSAKQLQDSGLPPSESLLQEIVSYSRNFSLVQKQALELSNSALVPGEVTSLKEIQDLIQTIAASEGQVEIREQALKVLDRVLAIAHREQSDFGPLQSVHGRARELHRAISESTLTQLHSDAESLVSGKHPVAAVLALVEQQDKLDDEQWVILEETVSAAFGKQIAVAISRGKLIVAEIPRAFQVPAAAKIEPVSPAVAEPLPEIIVIPSGNVAPKQVVVVPEIKILESPAPSAPMHEVIIVPSMEIPQSLQTKGSGNIVFGAPTATKPAPIEGTLGLKVLVHIQGIGDRTFGSQEYAGTKAQGRRVEGFQVNLEPAIPGLKVEYMAHVEGVGDTPWVSEQELAGFRDKGKRIEGFAVRLSGAQADKYDVFYTAHIQNIGDTKVASNGEYCGTRGKALRVEGINVWVVPSAKAQPAQPVGLKVLVHIQGIGDRTFSDREYAGSKGQGRRVEGFQMKIEPPVAGLKLQYMAHVESVGDTAWIEEGDLAGLRGKAKRIEGFAARLTGADADKYNVLYTAHIQNVGDTPTASNGQYCGTRGKGLRVEGITVWVEAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW23</accession>
    <name>A0A2G4EW23_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminotransferase class V-fold PLP-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_019990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53719">
        <property type="protein sequence ID" value="PHX53719"/>
        <property type="gene ID" value="CP500_019990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="4">
        <location>
            <begin position="53"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotran_5" evidence="4">
        <location>
            <begin position="214"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="417" mass="45683" checksum="D775DB22CAD2CB5F" modified="2018-01-31" version="1">MTKDKHRQQFPALANKAYFNYGGQGPLPEPALEAIYGAYKRVQLGGPFSGEIGAWVAQEAMLTRCAIANELAVPPETIALTEDVTVGCNIALWGIDWRSGDHLLLSDCEHPGIVASVMELQRRFNIEVSVCPLAATLNEGDAVAVIADYLQPNTRLLVISHILWNTGQVLPLAEIVKVCHQGYELPLTPLDQVLNEPPLTPPYEGGGQEELPVQNHKVRVLVDAAQSVGVLPLNLIESGVDFYAFTGHKWWCGPEGLGGLYVSDEALADLQPVFIGWRGIVTDANAKPIGLKPGAQRYEIATSAYPLYVGLRSAIALQHEWGTMEERYAEICRLSKYLWEGLSEISHVECLRTSAPEAGLVSFRLTNGMPHKKLVDLLEKQGIMVRTILNPDCVRACVHYFTTEAEIDKLVGAIAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW41</accession>
    <name>A0A2G4EW41_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000158">
        <property type="protein sequence ID" value="PHX53739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53739">
        <property type="protein sequence ID" value="PHX53739"/>
        <property type="gene ID" value="CP500_019840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="86"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="245" mass="28008" checksum="910B40548E923B4C" modified="2018-01-31" version="1">MSKKSDRLASNPEQNWFATDKSDSWPLLLSPVAARFDREYRGEPFALPEEVEAMPIFLESVAGTLQAKTVSPFWQIAKPQKNQRCLDIGCGVSFLIYPWRDWEAFFYGQEISSAARDALNARGPQLNSKLFKGVELGPAHRLKYEEDQFDLCIATGFSCYFPIDYWAIVMGEVKRVLKPGGHFVFDVLNPNAPLAEDWAILETYRTGEVFLEEIDDWEKLIKTVGAKIVKKQSGDLFQMYKVQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW68</accession>
    <name>A0A2G4EW68_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_019485</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53802">
        <property type="protein sequence ID" value="PHX53802"/>
        <property type="gene ID" value="CP500_019485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="14"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="417" mass="44732" checksum="32D505BBCDAB0D02" modified="2018-01-31" version="1">MPKLPSWFPRLSSQVWILAVGRFLSQSGTGFTLFYAPIYFVSQVGLSATAVGIGLGCGSISGIFGRILGGSFSDSKFWGRRRTLLLSAIISAVACFMLAAANDFPSLVVANLLMGFGVGLYWPATESMVADLADGEHRQEAFALTRLADNLGLQVGIILGGFLIALTGNYRSLFVIDGISFVIFFAVVWGAVSETYKPSTSVEAGKKTKKNGWMVALGDRTLLIYAVVNTMFTLYIAQIQTTMPLYFTNFVSVDASGKGFSTATITILFAFSTFLTVALQMPIARALRRFSCPRALMISALLWGIGFIAIGLTGMAATGNLFLAVVGLFFLSVATVAYTPFASGLVVELAPESLRGVYLAINSQCWAIGYLIGPPLGGWALDRGQFAANNFWLGLALSVSVAILILQIVDRRLKSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW77</accession>
    <name>A0A2G4EW77_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53812">
        <property type="protein sequence ID" value="PHX53812"/>
        <property type="gene ID" value="CP500_019550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="14725" checksum="BEB54701A07ABAA6" modified="2018-01-31" version="1">MNAEKLPQMLQAGFHLTLGATSFLIETLQDPVKRSENLEKLNSDLGILADELLEKGEMTDREARNFVDTIFSGASDRENKESESVSSKQSDSPTGTPSDSVAQPDVVLEIQELTAQMVALRTQLESLRAENSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWB5</accession>
    <name>A0A2G4EWB5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Circadian clock protein KaiB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000152">
        <property type="protein sequence ID" value="PHX53824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53824">
        <property type="protein sequence ID" value="PHX53824"/>
        <property type="gene ID" value="CP500_019420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048511">
        <property type="term" value="P:rhythmic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02978">
        <property type="entry name" value="KaiB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039022">
        <property type="entry name" value="KaiB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011649">
        <property type="entry name" value="KaiB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41709">
        <property type="entry name" value="PTHR41709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07689">
        <property type="entry name" value="KaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01248">
        <property type="entry name" value="KaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KaiB" evidence="1">
        <location>
            <begin position="182"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="30542" checksum="18AF3FEC76967AB6" modified="2018-01-31" version="1">MKADRPTLPKFFKGIALFTPGGDLIYCIDDRKQTQWHLHLCVALQEILGLSEPPHFLVPCYTATIDCWLDPRDRQLRIAAEAYPPVLRHQTLLNAVFETGDLVWRARVEEMCEPMAIATYHQQFPELWENHDLVVHWAIGESRSESGSSGIVPPSRFPKSQQTEVRQTALTEHTETQGYVLRLFVSGSNANTERTLETVHQLLEKALHHPYTLKVIDVFKHPEQAEKDQISATPTLIKVWPKPVRRIVGELNDVEKIMRLLSYSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWB6</accession>
    <name>A0A2G4EWB6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ADP-ribosylglycohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53768">
        <property type="protein sequence ID" value="PHX53768"/>
        <property type="gene ID" value="CP500_019660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="40730" checksum="BCFC928F591809E6" modified="2018-01-31" version="1">MRHSLSSKFQATLLGSALGNFIGIQYQNQLLGMRAETAELQPILQLTKHQQLPLTGGTSGPKSSNSKLQTGKNSSECGRLAVACAQSLIRCGGLDLKDWRDTWTEFTESELEHSPTTEGKIILHPGEAAVAALPIALFFHENKAKLREKLLLATEVWYNQSASECQTGVLAVGYAIARSLKERLDPATVIPQTITYLATDNALTELLSQVQILLEQGADLERATTHLYKSAIALQERQIKGENKSQTNSIVNPENFIPMAIAFYCFLSTPEDLSLSVFRAARCGIASPLTCALTGALSGAYNASTAIPVEWKSRYSATEGRQPSVWLTGNHAKIGQLANNLFAVWTGVYSPHSQSEVPVIRSVVAAPYVIRHHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWG9</accession>
    <name>A0A2G4EWG9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell wall hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53902">
        <property type="protein sequence ID" value="PHX53902"/>
        <property type="gene ID" value="CP500_018990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MurNAc-LAA" evidence="2">
        <location>
            <begin position="65"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="479" mass="52300" checksum="A7CBC48FAAA0BE0D" modified="2018-01-31" version="1">MGSIFVSAGHGGFEGNQRDPGAMAFGTTEAQELILIRDLLVPELRQRGIETFSVPDTLSLVQSIDWINNRCRAGDVAIEMHADAFSNPLVRGASAFYIGSNPKRKADADLILNGYLRRLPGMVNRGAKADTEAGVGSLGFCRHVAVPSLLIELGFLTNIDDLRIFQTRRRDIALGLADGLEAWLKNTDLKPLTPAPTPTPIPTPTPTPRPTPTPIPIPTPTPTPPPVTYALINININGAAHEEKGILVNGNAFVPSEVLDIFDVVPAAVNRRITYKGVVFVRAIDLRDRDIAVAWDQSTTSVSLRSRRDILAGVGKIMNRGQITAQQMTVFLNKNNSKALTQFPNLPQIYLQEAAAESVNHDLAFCQMCLETNFLNFGGSVKPEQFNFADMGVISTTSAGLSFPDARTGVRAQIQHLKAYGSTEPINQPLVKENVRFKFVKRGVALTVNELVGRWNSDPQYAQKILNTIRLLYENAGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWI2</accession>
    <name>A0A2G4EWI2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b6-f complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cytochrome b6-f complex subunit PetN</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Cytochrome b6-f complex subunit VIII</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">petN</name>
        <name evidence="12" type="ORF">CP500_019140</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 10">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cellular thylakoid membrane</location>
            <topology evidence="10">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the PetN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000145">
        <property type="protein sequence ID" value="PHX53881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53881">
        <property type="protein sequence ID" value="PHX53881"/>
        <property type="gene ID" value="CP500_019140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009512">
        <property type="term" value="C:cytochrome b6f complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045158">
        <property type="term" value="F:electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00395">
        <property type="entry name" value="Cytb6_f_PetN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036143">
        <property type="entry name" value="Cytochr_b6-f_cplx_su8_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005497">
        <property type="entry name" value="Cytochrome_b6-f_cplx_su8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03742">
        <property type="entry name" value="PetN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103451">
        <property type="entry name" value="SSF103451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="29" mass="3289" checksum="88C92E247C655C31" modified="2018-01-31" version="1">MDILSLGWVSLLVLFSFSISMVIWGRNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWN4</accession>
    <name>A0A2G4EWN4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nrdJ</name>
        <name evidence="4" type="ORF">CP500_018800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000138">
        <property type="protein sequence ID" value="PHX53944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53944">
        <property type="protein sequence ID" value="PHX53944"/>
        <property type="gene ID" value="CP500_018800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008998">
        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007869">
        <property type="entry name" value="Homing_endonuc_PI-Sce"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006142">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004042">
        <property type="entry name" value="Intein_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013345">
        <property type="entry name" value="RTP_Rdtase_AdoCbl-dep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05204">
        <property type="entry name" value="Hom_end"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00379">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="SSF55608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02505">
        <property type="entry name" value="RTPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50819">
        <property type="entry name" value="INTEIN_ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOD-type homing endonuclease" evidence="3">
        <location>
            <begin position="466"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="INTEIN_C_TER" evidence="2">
        <location>
            <begin position="665"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1176" mass="132109" checksum="D2E716C229AEDDED" modified="2018-01-31" version="1">MVRELERSSAREKRHLSDFPETAPAANPVFFRTYSRRTETGRETWADVCDRTVKGLQKLGNLTSEETQLLHRMQNELKTLASGRWLWVGGSKWIEQPENFSGAYNCSSTNILDWRAFGLLMDLAMMGCGTGAVLEPKYINQLPQISNRLTVTMQGEIGSTPAELRRQETEVKIAEKTATIYVGDSRQGWVKSYQALLELSTDERFAGEVQVYIDLSDVRPVGEPLKGFGGVANPVKLPDLYQRCSAILNKALGRQLNSVECCVLIDEAAVTIVAGNIRRCLPEDALVHTSKGLVPICDVQLGDLVQTPLGFQRVVDKFDQGFQDVYEIETNATYPRATLNHRQAVLADAQGGIVWKSVASLAEGDRLLHNTQVLPGTITHLPPDFTESRPSQSRTAKSFVVPELTAEVAWLIAFTHGDGYVALGRNKYDKPYGRVEWAMNSLDTELTPKIQAKINSALALFGLSAVHGVIKGENTAKSICSSIRLAEYFHRYIKQPNIPLTIPSWILQGSVDIRAAYLAGLMDSDGTVNGRPPHLVTSVYPSFVRQISAVLSSLGIAGRITTTYPQQSGWQIKYQLTIPALKERYNALISPHSLKGELRQGLKMYGFTVPGAIMREAHTYSEMRDMGFQGSRTVDANYERYIAEADISLDIPVTVKGLGSYNHVKTYDIEVEKAHCFYCDGYLTHNSAGMRQFESGDELGANAKNNLWQQDESGNWRIDPERDALRMANHTRVFHSKPTLEECIDAVHKQYYSGEGAIQWAGEAVARSNVDLLSTPSLKLEFLKAYNEGKAKDWLQKLYPDMTAGELEHRLVRVGLNPCGEIIGSNFFCNLSEIHLNQLDPYNFKEQEEAFTAGALSVAVLLNHKFSEPRYQYSRELDPIVGVSFTGLFDFFVHGFGVEWLRWWVEGRPQTDQGMAFKQREEEYLTGWREIVNRVVWDYCDRHSLKRPNRCTTVQPSGTKSLLTGASPGWHPPKSQRFIRRITFGKNDPVALACIDYGYNVIPSQSDKDENGNLLNNPFDERCTEWLVEIPVAVSWADLPGADEIEINKFSAAAQMDFYMQVQKFYVRHNTSATIELRENEVESLGTRIYEAIRDDEGYISAALLSRFDALETFPRLPFEPVSKEIYETMLKDVLVRRQIDVFQVALSRYDLGEMMDSGPAGCDSDKCLMPETKAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWP8</accession>
    <name>A0A2G4EWP8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Ornithine carbamoyltransferase</fullName>
            <shortName evidence="5">OTCase</shortName>
            <ecNumber evidence="3 5">2.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argF</name>
        <name evidence="9" type="ORF">CP500_018965</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="3 5"/>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53898">
        <property type="protein sequence ID" value="PHX53898"/>
        <property type="gene ID" value="CP500_018965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01109">
        <property type="entry name" value="OTCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024904">
        <property type="entry name" value="OTCase_ArgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="148"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="51"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ornithine binding" evidence="5">
        <location>
            <begin position="227"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="263"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="306" mass="33759" checksum="78BB069DF9E8BED8" modified="2018-01-31" version="1">MDSLKGRDLLSLADLSIDELNYLLDLAASLKSGMVKLKRNKVLGLLFSKASTRTRVSFTVAMYKLGGQVVDLNPNVTQVSRGEPLVDTARVLDRYLDVLAIRTFEQKDLVTFANYAKIPVINALTDDEHPCQVLADLMTVKESFGKLKEVTLTYLGDGNNMANSLMLGCAMMGMNVRIACPEDFMPNPDIVEKAKAIANGKTEVTVSVDAKAAVKNAQVIYTDVWASMGQEEEAKTRIPLFEPYQVNQELVELADKNAIVLHCLPAHRDEEITDAVIEGSQSRVWDQAENRMHVQQALLAGILESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWV5</accession>
    <name>A0A2G4EWV5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54014">
        <property type="protein sequence ID" value="PHX54014"/>
        <property type="gene ID" value="CP500_018435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7473" checksum="D2C63C354B6F5EB8" modified="2018-01-31" version="1">MTAFSEANKRIGIDKFILSGALSLAQLEFTKTADNTGQRVATLLVLFLSLHRWTSFDKKRFQLPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWW9</accession>
    <name>A0A2G4EWW9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Photosystem II 12 kDa extrinsic protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">PS II complex 12 kDa extrinsic protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">PSII-U</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">psbU</name>
        <name evidence="4" type="ORF">CP500_018290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">With PsbO,P,Q and V forms the oxygen-evolving complex of photosystem II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cellular thylakoid membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Lumenal side</orientation>
        </subcellularLocation>
        <text evidence="3">Associated with photosystem II at the Lumenal side of the thylakoid membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PsbU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000130">
        <property type="protein sequence ID" value="PHX54045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54045">
        <property type="protein sequence ID" value="PHX54045"/>
        <property type="gene ID" value="CP500_018290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042549">
        <property type="term" value="P:photosystem II stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00589">
        <property type="entry name" value="PSII_PsbU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010527">
        <property type="entry name" value="PSII_PsbU"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06514">
        <property type="entry name" value="PsbU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="3" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013975952" description="Photosystem II 12 kDa extrinsic protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="15968" checksum="6E84AF042F8E5DE2" modified="2018-01-31" version="1" precursor="true">MKRLGRLLAVLGLVLGCFAWAGDQSAIAASLSRFVLPSSSLIAVEAPSRTNRADEKLATEYGKKLDLNNSAVRDFRDYRGLYPTLAGLIIRNAPYEKIEDVLNIPNLSEPQKKFLEANMDKFTVTDVESVFIEGDTRLNNGLYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX49</accession>
    <name>A0A2G4EX49_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000125">
        <property type="protein sequence ID" value="PHX54101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54101">
        <property type="protein sequence ID" value="PHX54101"/>
        <property type="gene ID" value="CP500_017935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="727" mass="81978" checksum="DDEF81BD3C3A762F" modified="2018-01-31" version="1">MSIPSQKVSSWNKLIYQRLKQALELNFRRQIFIAACDDLCLRDCLAARLEAELATTEPTKPDEISLSPIAHPRFVSLQLNLGDPNPWGSIATWLAEHPLAENARNYSQLPGFQILGAEHLTRHSAAVQWSFLSYLRDIETHLEVWESPLLLWVSRPWLNSIEQSAPEFWHWRTGVFEFEGEPTPSARQWEFGDKQELGEQFLSSKSGQSKVSNSPSPILNSSSRRLNSKSIELADLVLAAASEELETKNQTPSGEYLQPLQTLQYIELLQENQCASEVLALAYQSLGNFYRDRIQAGDASRQNLIIAIRAIEQVLQYLEIDRNLEQNPQQTPECTLLIDEFKQNLTQYTQESNSLLPIADLVNDLGTLYWMLSRSRQESYPQENPTSDPVFCLEHSIALYREGLNKKDGSVELQTRARLNKNLGTALADLAHYQNKTENLQQAVTAYQQALLDIDSTSEPQQYAATQNNLATAYWSLAQDGQPIVYLKSAISAYSQALTCYNPSTEPLNYAGVQNNIGTVCWNLAQHEPEEILLVRAIAAYREALKYRTRELVPAAAAATQNNLGTAYWHLANQFQQQRHRAESLQQAILGYEAALDIAGELDRTQLTFDTLATRNNLGLAHYQLATEPDFALNKATQTQHLEAALYQQLQVCAGWEQHLQDKQLTYGDKLNLQDHANAQASDSRQTALSYIVKTIRAFYSECGLQGQNLALSKVPGDLLPEILRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX58</accession>
    <name>A0A2G4EX58_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54068">
        <property type="protein sequence ID" value="PHX54068"/>
        <property type="gene ID" value="CP500_018040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="13254" checksum="722EAA220F93C7A5" modified="2018-01-31" version="1">MQITESIHAAILISNLEKSEHFYTNVLGLSKLDRILKFPGVWYQVGNFQIHLILAAKIIPDAVDSDKLGRNRHLAFSVADLEIAKQKLIAHNCQIQMSASGRSALFTQDPDGNIIELSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX63</accession>
    <name>A0A2G4EX63_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2726 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000122">
        <property type="protein sequence ID" value="PHX54132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54132">
        <property type="protein sequence ID" value="PHX54132"/>
        <property type="gene ID" value="CP500_017770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024402">
        <property type="entry name" value="DUF2726"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10881">
        <property type="entry name" value="DUF2726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2726" evidence="1">
        <location>
            <begin position="24"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="20008" checksum="1995912ABD59FA6F" modified="2018-01-31" version="1">MLYAFDCDNSLSSFPQFQSGEIINELETIAIDILEMILGDRFRYCPQVPLEIICSRPETFTRLPIGLWKFWVSSRVDIALMERGCGVSRKAKLVIECQSHWHDRPEVQERDRKKARLLASVGVPLVYLRQIDRDRRFYRFYTPKGQKEVCYNSITQQGRTELEAFLQRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX65</accession>
    <name>A0A2G4EX65_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54123">
        <property type="protein sequence ID" value="PHX54123"/>
        <property type="gene ID" value="CP500_017830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="7908" checksum="D848CDE4C62C9D20" modified="2018-01-31" version="1">MNPQSGTKSPLDRKPQIPLTELHQKIDAGVKIAIAKAIEKHRKLGESISIGQDGKVITLTADQIPPLKLDNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX71</accession>
    <name>A0A2G4EX71_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Toxin-antitoxin (TA) system antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000121">
        <property type="protein sequence ID" value="PHX54142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54142">
        <property type="protein sequence ID" value="PHX54142"/>
        <property type="gene ID" value="CP500_017740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="8443" checksum="37FCAB0557D2E394" modified="2018-01-31" version="1">MLTKTVDVQEAQTNLKELLSLALKGIEVVLTEGGIPLVRLAPIASPTKQRTAGLHAGAIWTSDDFDEPLPDEFWTGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXB6</accession>
    <name>A0A2G4EXB6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA modification GTPase MnmE</fullName>
            <ecNumber evidence="6">3.6.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mnmE</name>
        <name evidence="6" type="synonym">trmE</name>
        <name evidence="9" type="ORF">CP500_017525</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000117">
        <property type="protein sequence ID" value="PHX54184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54184">
        <property type="protein sequence ID" value="PHX54184"/>
        <property type="gene ID" value="CP500_017525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00379">
        <property type="entry name" value="GTPase_MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004520">
        <property type="entry name" value="GTPase_MnmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00450">
        <property type="entry name" value="mnmE_trmE_thdF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51709">
        <property type="entry name" value="G_TRME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TrmE-type G" evidence="8">
        <location>
            <begin position="225"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="235"/>
            <end position="240"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="254"/>
            <end position="260"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="279"/>
            <end position="282"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="461" mass="49944" checksum="077F242B3DF56CFF" modified="2018-01-31" version="1">MAESLTKGGTIAAIATAIVPQQGSVGIVRVSGSQALKIAETLFRSPGKQIWDSHRIIYGYIRHPKTQELVDEALLLIMKAPRSFTREDVVEFHCHGGIMAVQQVLQLCLENGAKLAQPGEFSLRAFLNGRLDLTQAESIADLVGAKSPAAAQSALAGLQGKLAKPIRLLRTTCLDVLAEIEARIDFEEDLPPLNEAQTVLEIQHILDELSTILATADRGELLRSGLKVAIVGRPNVGKSSLLNAWSRCDRAIVTDLPGTTRDVVESQLVVGGIPVQVLDTAGIRETEDKVEKIGVERSRIAAQQADLVLLTIDAESGWTAGDSDIYEQVKHRQLIIIINKIDLVKTPPKLPFSSETHRIVTTAAALELGIADLETAILEAVNSQNLQAENLDLAINQRQAAAITKAKFCIEQCLVTIGDKLPLDFWTIDLRGAIQALGEVTGDEVTESVLDRIFSRFCIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXD2</accession>
    <name>A0A2G4EXD2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54195">
        <property type="protein sequence ID" value="PHX54195"/>
        <property type="gene ID" value="CP500_017440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8226" checksum="94156F6F45B7DFBE" modified="2018-01-31" version="1">MLLIQKIAVPAKTWKVIEVLDRQGLGVRQSCERYLMTWVCLGRPSLSDDLGFSWMGAATAPQSKNDTNVAFGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXH3</accession>
    <name>A0A2G4EXH3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GUN4 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54235">
        <property type="protein sequence ID" value="PHX54235"/>
        <property type="gene ID" value="CP500_017165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16383">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008629">
        <property type="entry name" value="GUN4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037215">
        <property type="entry name" value="GUN4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032192">
        <property type="entry name" value="GUN4_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34800">
        <property type="entry name" value="PTHR34800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05419">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16416">
        <property type="entry name" value="GUN4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140869">
        <property type="entry name" value="SSF140869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GUN4_N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="GUN4" evidence="1">
        <location>
            <begin position="94"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="237" mass="27211" checksum="1653DECE52E3E6C4" modified="2018-01-31" version="1">MTDSISTSPLDSIADTAELRSQLRSGSEKTQLQFLQQMADSNWDVLMEFLLERQSDEPTAVMGKAYQILYHADSPKATEFLQAHFPTGVVPLRSDSNIDYTPLQQLLALQEFQEADRLTLDKLCELAGETARVRKWLYFTQVESLPVADLQTINTLWKVHSEGKFGFSVQREIWLSSGKNWDKLWPLIGWKKGNNWTRYPQEFIWDLSAPRGHLPLSNQLRGVQPFSALMAHRAWVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXK7</accession>
    <name>A0A2G4EXK7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000117">
        <property type="protein sequence ID" value="PHX54180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54180">
        <property type="protein sequence ID" value="PHX54180"/>
        <property type="gene ID" value="CP500_017500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08352">
        <property type="entry name" value="VOC_Bs_YwkD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037478">
        <property type="entry name" value="YwkD-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="128" mass="14866" checksum="D41809992988F15B" modified="2018-01-31" version="1">MKIKKIHHVAIICSNYEASKKFYLEVLGCSIIQETFRIERNSYKLDLQVGNGDMIELFSFPHPPERVDNPEACGLRHLAFAVEDIDESVAYLESKQVDVEEIRLDEITGKRFTFFKDPDNLPLEIYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXT2</accession>
    <name>A0A2G4EXT2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 10 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54345">
        <property type="protein sequence ID" value="PHX54345"/>
        <property type="gene ID" value="CP500_016675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003790">
        <property type="entry name" value="GHL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02638">
        <property type="entry name" value="GHL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHL10" evidence="3">
        <location>
            <begin position="50"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="403" mass="46716" checksum="526808AE518C89FE" modified="2018-01-31" version="1">MFANKLTIKQYGWRRIVAFILAFTIALISTAIFSPRLSAQTPPKTPRNTELRGVWLTNIDSDVIFSPKNISDAVNRLDELNFNTIYPTVWQGGYTLYPSAVAKRVFGKSIDPSPGLQNRDILKEIIAESHQKGIAVIPWFEFGFMAPADSELARLHPDWLAKRRDGSTIWKEGTHDRVWLNPFHAEVQQFILDLIVEIVDKYDLDGIQFDDHFGLPVEFGYEPTTVLMYQKAIKSQPSNDARETFWIRWRADRINDFIARVFHAIKSRKQKCIISLSPNPFHFALPAHLQDWFTWERRGYIEEIVLQVYRSDIKRFNAELEREEVILAKDHIPTAIGILTGLKNNSISLQQIQEQVQEVRKRNFAGVSFFFYESLSNWAKETPEQRNSALRSFFPTKIQRPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY14</accession>
    <name>A0A2G4EY14_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0145 protein CP500_016440</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0145 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54376">
        <property type="protein sequence ID" value="PHX54376"/>
        <property type="gene ID" value="CP500_016440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00338">
        <property type="entry name" value="UPF0145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002765">
        <property type="entry name" value="UPF0145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068">
        <property type="entry name" value="PTHR34068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01906">
        <property type="entry name" value="YbjQ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="SSF117782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="11543" checksum="C358911C223AF462" modified="2018-01-31" version="1">MIVTTTDIIQGAEIQSYLGIVTAEVVYGTNALRDFFAGIRDIIGGRTGSYEEVFLKGQRDALAELEQRAQRMGANAVIGVEIDTGTINVDTKGALLLITAVGTAVRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY80</accession>
    <name>A0A2G4EY80_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nrdR</name>
        <name evidence="11" type="ORF">CP500_015960</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NrdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54479">
        <property type="protein sequence ID" value="PHX54479"/>
        <property type="gene ID" value="CP500_015960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ATP-cone" evidence="10">
        <location>
            <begin position="49"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="7">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="180" mass="20622" checksum="BDECDF388DBF6281" modified="2018-01-31" version="1">MRCSSCQHTNSRVLESRSAESGQSIRRRRECLNCQHRFTTYERIEFVPITVIKRDGKRESFDRSKLVRGLVRACEKTGLSSGQLETLAEEIEAQLQGRSLREVTSSDIGELVLLHLRPLSEVAYVRFASVYRQFRGIRDFVDTLNHLQSPLIEALCPETPSENDRDLSEFDELTVDCQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYD3</accession>
    <name>A0A2G4EYD3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000097">
        <property type="protein sequence ID" value="PHX54488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54488">
        <property type="protein sequence ID" value="PHX54488"/>
        <property type="gene ID" value="CP500_015855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="233" mass="26744" checksum="227DB291DF810BF9" modified="2018-01-31" version="1">MSKISKFLSSILKNPLTEYLRFLANWWNNKFKYNSFYQDYMALVTNSTISHNVSVSSRVAIENSVIGSYTYVRDNTRIFNGIVGNFCSIGPNCIIRLGVHPVGIFVSSHPIFYSPKMLVGTTFVDQKYFEEEEKTVYIGNDVWIGSNVIVVDGVTIGDGAIIAAGAVVTKDVPPYAICGGIPAKLIRYRFDEQKIDFLLKFKWWDKDEQWLRKNVKDFHNIDKFIHIYNRENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYE1</accession>
    <name>A0A2G4EYE1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000094">
        <property type="protein sequence ID" value="PHX54531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54531">
        <property type="protein sequence ID" value="PHX54531"/>
        <property type="gene ID" value="CP500_015665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="8683" checksum="C79CBF5668315C0B" modified="2018-01-31" version="1">MKSLPLPPKRESLLLPPLIVSSDSSPNNKSEPILPSSKSFPLVSLTKPRTPPYKVSSPLSPSKVSLPSSPQIRSLSLPPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYM4</accession>
    <name>A0A2G4EYM4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54629">
        <property type="protein sequence ID" value="PHX54629"/>
        <property type="gene ID" value="CP500_014990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06533">
        <property type="entry name" value="Glyco_transf_WecG_TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004629">
        <property type="entry name" value="WecG_TagA_CpsF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34136">
        <property type="entry name" value="PTHR34136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03808">
        <property type="entry name" value="Glyco_tran_WecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00696">
        <property type="entry name" value="wecG_tagA_cpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="243" mass="27297" checksum="C5AFCAD667029271" modified="2018-01-31" version="1">MNRSHPQFSVLGLPVHILDDHADWLIDRLHQGLGSHVVTLNAEMAMQAEQNPALADIIHSAELVIPDGAGVVLYLRIQGKNAKRFPGIELAESLLQQAGKLPDGESILFFGGSPEVAIAAAETWQQQMNGISIISQHGYLSPEAEPEFLETLKKIQPKMILVGLGVPRQEFWITKHRHLCPQSIWVGVGGSFDIWAGTKTRAPAWFCDNHLEWLYRLYQEPWRWRRMLALPQFAFKALGNLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ63</accession>
    <name>A0A2G4EZ63_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="7">Glutamate N-acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">Ornithine acetyltransferase</fullName>
                <shortName evidence="7">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="7">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">N-acetylglutamate synthase</fullName>
                <shortName evidence="7">AGSase</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">argJ</name>
        <name evidence="8" type="ORF">CP500_014200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Heterotetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ArgJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="7"/>
    <dbReference type="EC" id="2.3.1.1" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54813">
        <property type="protein sequence ID" value="PHX54813"/>
        <property type="gene ID" value="CP500_014200"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="PTHR23100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5023258999" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="7">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023259000" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="7">
        <location>
            <begin position="191"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="7">
        <location>
            <begin position="190"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="413" mass="43068" checksum="5FD38ADB8D7F3507" modified="2018-01-31" version="1">MSDWKVISGGVTAPRGYRASGITAGLKPSGAPDLSLILSEVDAIAAGVFTTSTVRAACVDYCRQRLQVKPSAKAILCNAGQANAATGEQGLADALESAKLLGEALNIPSESILLASTGVIGQRIKMERLRAGIPQLVAEASSTGSDAAAKAICTTDLVPKTIALETIFGDRPVRIGGICKGSGMIHPNMATMLAFVTCDAAVSSHLWQEMLSRAANRSFNQITVDGDTSTNDSLIALANGQSRTPAITEMGADAEKLEAMLTEVCVHLAKAIARDGEGATCLVEVQVSGAPDEVSASKIAKTIVGSSLVKAAIFGRDPNWGRIAAAAGRAGVMFEQENLRIQLGDFLMMENGQPLPFDKSAASNYMKAAAEGEYLKNDTVLIQVSVGNGSGFAKAWGCDLSYDYVKINAEYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZI6</accession>
    <name>A0A2G4EZI6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome segregation protein SMC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54926">
        <property type="protein sequence ID" value="PHX54926"/>
        <property type="gene ID" value="CP500_013485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="2">
        <location>
            <begin position="27"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="394" mass="45234" checksum="0D5E8FFEF8513436" modified="2018-01-31" version="1">MKIVSIRIKNYRLFENIEITDIPALCVIIGANGTGKSTLFDVFGFLRDALTNNIRQALQIRGGFNEVVTRGKEKEDIEIELKFRMKILETERLVTYSLIIGQDQKRPIVKREILRYKRGEHGKPFHFLDFQNGKGYAIINEEDFEQADEELEREEQQLESSDILAIKGLGQFQRFKAASAFRSLIENWHVSDFHISDARGSKDALYAEHLSATGDNMAVVAQYIYQEHPEIFNQILQRMQARVPGISKVEAKNTEDGRLILKFQDQAFKDPFIDRYVSDGTMKMFAYLILLFDPKPHPLLCVEEPENQLYPSLLHELAEEFASYAHRGGQVFVSTHSPDFLNAVPLDSIFWLIKEKRVTKIQKATDNETLKNLVAAGDLPGYLWNQGWFEGVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZI7</accession>
    <name>A0A2G4EZI7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4276 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54925">
        <property type="protein sequence ID" value="PHX54925"/>
        <property type="gene ID" value="CP500_013480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025455">
        <property type="entry name" value="DUF4276"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14103">
        <property type="entry name" value="DUF4276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="21850" checksum="CDF970EFE475D43D" modified="2018-01-31" version="1">MSYDLIFLLEEPSIKNVLDQLLPQVIPPEVTYICIPHQGKQDLANSIPKKIKAFEYAPKTKFIIVHDQDSHDCKELKSELFRICQTAGQANILIRIICRELESWFLGDLAAVEKAYNLKPNSLSKQQSKQKYRDPDRLNSAKQELKKLINEYSAEYYAGTHSKAIAPHLSLTENKSRSFQVFLESLKKLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZM9</accession>
    <name>A0A2G4EZM9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Photosystem II D2 protein</fullName>
            <shortName evidence="13">PSII D2 protein</shortName>
            <ecNumber evidence="13">1.10.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Photosystem Q(A) protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">psbD</name>
        <name evidence="16" type="ORF">CP500_013420</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>2 a plastoquinone + 2 H2O + 4 hnu = 2 a plastoquinol + O2</text>
            <dbReference type="Rhea" id="RHEA:36359"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:30212"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
            <dbReference type="EC" id="1.10.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <text evidence="13">The D1/D2 heterodimer binds P680, chlorophylls that are the primary electron donor of PSII, and subsequent electron acceptors. It shares a non-heme iron and each subunit binds pheophytin, quinone, additional chlorophylls, carotenoids and lipids. There is also a Cl(-1) ion associated with D1 and D2, which is required for oxygen evolution. The PSII complex binds additional chlorophylls, carotenoids and specific lipids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cellular thylakoid membrane</location>
            <topology evidence="3 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">2 of the reaction center chlorophylls (ChlD1 and ChlD2) are entirely coordinated by water.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 14">Belongs to the reaction center PufL/M/PsbA/D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.9" evidence="13"/>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54948">
        <property type="protein sequence ID" value="PHX54948"/>
        <property type="gene ID" value="CP500_013420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045156">
        <property type="term" value="F:electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010242">
        <property type="term" value="F:oxygen evolving activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009772">
        <property type="term" value="P:photosynthetic electron transport in photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.85.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01383">
        <property type="entry name" value="PSII_PsbD_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036854">
        <property type="entry name" value="Photo_II_D1/D2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000484">
        <property type="entry name" value="Photo_RC_L/M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005868">
        <property type="entry name" value="PSII_PsbD/D2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33149">
        <property type="entry name" value="PTHR33149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00124">
        <property type="entry name" value="Photo_RC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00256">
        <property type="entry name" value="REACTNCENTRE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81483">
        <property type="entry name" value="SSF81483"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01152">
        <property type="entry name" value="psbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00244">
        <property type="entry name" value="REACTION_CENTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="11 13" id="KW-0157">Chromophore</keyword>
    <keyword evidence="13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 13" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="13" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7 13 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>ChlzD2</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>pheophytin a</name>
            <dbReference type="ChEBI" id="CHEBI:136840"/>
            <label>D2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>pheophytin a</name>
            <dbReference type="ChEBI" id="CHEBI:136840"/>
            <label>D2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>PD2</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>a plastoquinone</name>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <label>Q(A)</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX54948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="352" mass="39323" checksum="6A1BA787DEDDD18C" modified="2018-01-31" version="1">MTIAVGRAQNEQGIFDVLDDWLKRDRFVFVGWSGILLFPCAYLAIGGWLTGTTFVTSWYTHGLASSYLEGANFLTVAVSTPANSLGHSLLFLWGPEAQWDFTRWFQLGGLWAFVALHGAFALIGFCLRQIEISRLVGIRPYNALAFTGPIAVFVSVFLLYPLGQSGWFFAPSFGVAAIFRFLLFLQGFHNWTLNPFHMMGVAGILGGALLCAIHGATVENTLFEDGEGSNTFPAFNPTQAEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVTGLWMSSLGIVGLALNLRAYDFVSQELRAAEDPEFETFYTKNILLNEGIRAWMAPTDQPHENFIFPEEVLPRGNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZN0</accession>
    <name>A0A2G4EZN0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54965">
        <property type="protein sequence ID" value="PHX54965"/>
        <property type="gene ID" value="CP500_013155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="215" mass="23874" checksum="6996F83AF8AD8FF1" modified="2018-01-31" version="1">MKKLKLALSFLLITLIVAIFTLLSWILESGELSLSAMEPSVLRANQSLSEVRVAQEPQPQQLRVQDAWKFVYEKLPDFPIANNYISKETGKVDPNNTLVGRLIRYHVFVKGRPPNYRFDWKLSLADYLGVTPDYLVESVYPGNDVLRSNPMEGDRAAIQSLNRSQRDALVQALVDVFTGDSGPKRAPTTGGKPEGRSNSPTIPEPQPGDAKLLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZS4</accession>
    <name>A0A2G4EZS4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UPF0182 protein CP500_013085</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_013085</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UPF0182 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55010">
        <property type="protein sequence ID" value="PHX55010"/>
        <property type="gene ID" value="CP500_013085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01600">
        <property type="entry name" value="UPF0182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005372">
        <property type="entry name" value="UPF0182"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39344">
        <property type="entry name" value="PTHR39344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03699">
        <property type="entry name" value="UPF0182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1000" mass="113138" checksum="A70D059F7DEBB299" modified="2018-01-31" version="1">MTKRLVYQITLLIAGLGLILELASRLVAEILWFQEVGYLEVLLLRLKTQGLAGVIPTAISAVFLMGNLALARHLQHPIEEAKSPISGGLFASVNLKKMGENYQMPAAKSLLAFPWLLLALLGLSAIAALMVIHLGQLAAGSLAGLSMAGGLSVPPIQLGWESIGLIVVQLFSDWWELSVVLGLMLAVTIKPDFGLRAIAIFVSLAIGIIIASRWTKVLQYFHPINFNATDPIFSQDISFYVFILPILELFSFSLTVVFLYGLVSCTFTYLLSGNSLSQGIFWGFSRSQQRHLYGLGAALMLATGFHYWLARYELLYSRGDVSYGANYADATVRLPLYGFFSFVAWAIPFGIASLHALLIISPIFQLKIKNKKFQKIIFSFSILICLLIFLLPQMVQQLIVKPNELAQEKRYIKNSIAFTQKGFNFKEIEIKTFDPEGKLTYSDLEKNQLTISNIRLWDKRPLLQTNRQLQQIRPYYKFLDADIDRYTVKNETGKMAESQSQQVILAARELDYTAVSPEAQTWVNEHLVYTHGYGFTLSPVNTVGVGGLPDYFVKDIGVDAGSGETALDITSDRIRVSIPIGHPRIYYGEVTDTDVMTPTKVKEFDYPSGKDNVYNIYNGKGGIAIGSIWKRWIFANYLKNWQMAITRNFTPETKLLYRRNIQKRVRAIAPFLRYDSDPYLVVANAHLGTGDLTEKEPSKTAQNTQSLPSVGKNSPNYLYWIFDAYTTSDRYPYSDPGKNEFNYIRNSVKVVIDAYNGSVNFYVVNSSDPIIKSWIAIFPRLFKPIEQMPPAIRKHMRYPMDLLKVQSERLLTYHMEDPQVFYNREDLWRVPNEIYGGEQQPVEPYYLITKLPTEKSEEFILLLPFTPVSRNNLIAWIAGRSDEGDYGKLLLYQFPKQRLVYGPEQIEALINQDPVISEQISLWNRQGSKAIQGNLLVIPIEQSLLYVEPLYLEADRNSLPTLVRVIVAYENRIVMAETLDEALKALFQKKSTNTGMGDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZV7</accession>
    <name>A0A2G4EZV7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-dependent helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_014555</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54727">
        <property type="protein sequence ID" value="PHX54727"/>
        <property type="gene ID" value="CP500_014555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="3"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="34"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="240"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="465"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="3"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="493" mass="54378" checksum="0B0B06DF5AC2F6C3" modified="2018-01-31" version="1">MNSLFEGLGLSEELVLHLETLGFTEPTPIQVQAIPHLLAGRDVVGQAQTGTGKTAAFSLPILERIDLDVAGVQALVLTPTRELAMQVTEAIRDLSGISSDGPVKVGRSLQVLTVYGGQSIDRQMQRLKRGVHIVVGTPGRILDMLSRGSLKLDRLKWLVLDEADEMLSMGFIQDVEKILDAAPQERQTAFFSATMEASIRKLVARHLRNPVNVTVEQPKATPKRISQGVYMIPRGWTKARALQPILEMEDPESALIFVRTRQSAAELTSQLQAAGHSVDEYHGNLNQAQRERLLHRFRQCQVRWVVATDIAARGLDVDHLTHVINYDLPDSVESYVHRIGRTGRAGREGTAITLIQPVDRRKLRLIERHVRSNLTVRVIPTRAQIEARQLEKMQGKVREALAGERMASFLPLVSQLSEEYDSHAIAAAALQMAFDQSRPAWMGQDYAQQEDAPIAENGVKPILIKKRAKGGAPSNSLSPSLSGASGSPVPQNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZY9</accession>
    <name>A0A2G4EZY9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutaredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55064">
        <property type="protein sequence ID" value="PHX55064"/>
        <property type="gene ID" value="CP500_012640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="11733" checksum="11348B0EE97B5790" modified="2018-01-31" version="1">MRLILYSKPGCHLCEGLQEKLQQIENLKFQLEVRDITDRDDWFQAYQYEVPVLSKVQQEGINSAGDAVFSPEELLPRPSPRCTVAQLTQLLQKYLYTDKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F039</accession>
    <name>A0A2G4F039_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55134">
        <property type="protein sequence ID" value="PHX55134"/>
        <property type="gene ID" value="CP500_012175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="257"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="322" mass="36766" checksum="B592FCB1C62B99F9" modified="2018-01-31" version="1">MKFINPKTDYAFKKIFGSDQSQDILISFLNAIVYQGETFITSLEIIDPYAPGRISGLKTTYFDVKALLNNGENVLIEMQAFNVPAFGKRILYNTAKMYVNQLKLGEVYPELRAAIGVAVTDFIMFDEHSKVISQFILKEDELLLNYQHSPLKLVFVELPKFNKTLEELTNVTDKWLYFLRRAPDLEVVPASMSIVPEIEKAFTIADRVNLSLEEVDDLEKREQFERERVGALELSKAEGLAEGIQIGEQIGEQRGEQRGEQRGKINLIKRQLQRRLGELNQEIEARLSQLSSEQLSALAEDIFDFSSVADLSSWLETNIIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F044</accession>
    <name>A0A2G4F044_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
            <shortName evidence="12">UDP-3-O-acyl-GlcNAc deacetylase</shortName>
            <ecNumber evidence="4 12">3.5.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lpxC</name>
        <name evidence="13" type="ORF">CP500_013895</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the LpxC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.108" evidence="4 12"/>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54817">
        <property type="protein sequence ID" value="PHX54817"/>
        <property type="gene ID" value="CP500_013895"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008759">
        <property type="term" value="F:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00388">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="PTHR33694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00325">
        <property type="entry name" value="lpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX54817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="281" mass="29984" checksum="27F52F6B2EB60F92" modified="2018-01-31" version="1">MTQSTLASEFELSGVGLHSGEQTRVRVLPANLGEGRYFVRTDLPGAPIIPAKVEAVSQTALSTELSATADVQIRTVEHLLAALAGMGVDNARIEVDGPEVPLLDGSALVWVEAIAHTGLVAQELVHPPAVNGQLSPIANPVWVRHGDAFVAALPAAETRFSYGIDFDEPAIGNQWYSWSPEAESFASAIAPARTFGLARQVDQLRQAGLIKGGSLENALVCDRSGWLNPPLRFANEPVRHKILDLVGDLSLLGTWPTAHYLAYKASHNLHIQLGLALSSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F049</accession>
    <name>A0A2G4F049_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4276 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55144">
        <property type="protein sequence ID" value="PHX55144"/>
        <property type="gene ID" value="CP500_012225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025455">
        <property type="entry name" value="DUF4276"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14103">
        <property type="entry name" value="DUF4276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="223" mass="25214" checksum="78576A001ACB5115" modified="2018-01-31" version="1">MRVIIYVEGPSDKNAMEALLVNLIDKKSEEGVSIEFFPIKGKNNDRGGDAKKDLLLNAPTKAVNILCNNPNSIAIILPDLYPKNKGFPHETFQQLKTGIMENFSQALQKKGIQDERLKERFKVFCFKYEMEALILAAESALRDKLGVTSLAVTWTIPVEDQNHDRPPSEIVEQLFRDSGKGYNKTVDAKLILGKTSYQEIADKCTQCFKPFVEFIEGIHTEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F075</accession>
    <name>A0A2G4F075_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54847">
        <property type="protein sequence ID" value="PHX54847"/>
        <property type="gene ID" value="CP500_013780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="9525" checksum="2D1B8381E74F81F4" modified="2018-01-31" version="1">MKVGSETQVIVRVPNEPTSRYVKVGQRLSNGRVLVKRVDVKSGADPIVILEENGVEVAKAVGEKPPSREPKPANAVISRLPNAGRATGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F078</accession>
    <name>A0A2G4F078_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55172">
        <property type="protein sequence ID" value="PHX55172"/>
        <property type="gene ID" value="CP500_012375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="169" mass="17686" checksum="3CF6F8566D8E5F8D" modified="2018-01-31" version="1">MNHLSVKSLAFYAIAIGSVTVLFKVVTAYGEANLKAAPAIAGDYRFNATNLPECLKSDILVLTIQQSGVYLSGNLKSDGSSVDRKTTTSEKPTLAGKWENQGLSLSGIVPNLTGCGESTGGGSQKSLVKLRGIVEGESLKGKISLLENAVGSDFTAQRLAVTKGERQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0E2</accession>
    <name>A0A2G4F0E2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cystathionine gamma-synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_011865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55229">
        <property type="protein sequence ID" value="PHX55229"/>
        <property type="gene ID" value="CP500_011865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="384" mass="41189" checksum="70C7FE6BCC28694C" modified="2018-01-31" version="1">MQINPGIETLAVHAGHPLDPGTDAVTPAIHLSTTFARQSDGSYQHPYDYIRCTNPGRDNLEKCLCELEGGEAAAAVASGSAAAASVFLALEPGAHVVAPLDAYCGTGLLLNTVFARWHLKSTFVDMTDLNQVEKAISIPNTQLVWLETPSNPLLKISDIAAIAQMAHQVGARCVCDNTWATPILQRPIELGADLVTHSFTKYLGGHGDAMGGIVVSRVKDEFFERIRQIQVGMGIGNAPFDAWLILRGIQTLPLRIKASSEAASYIAQFLSNHPKVKRVYYPGLPEHPGASLAARQMLYGGGMVSFQVGSREEAFQVAGKLQVFTSATSLGTVKSLVEIGALMESMQNLDTSNVETVIPDNLLRLSVGVEDVKTLILDLEQALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0H5</accession>
    <name>A0A2G4F0H5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55255">
        <property type="protein sequence ID" value="PHX55255"/>
        <property type="gene ID" value="CP500_011785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="622" mass="69751" checksum="17F31A39196B7FC6" modified="2018-01-31" version="1">MPESTSLRDRYLALIDKIVEITLKGQIRSKEQVYQMLVQDIGTGTGEIFERCFGERLDATENLLRNEKDEIKQAKANRTLRALKTIQGEWERWQKDNRVSSAIASAIQQILTAESNTRLLTLFQVIDPNKELPLTLDQLQQLAKSLHQQMLQTSNPETERDLQQITAGIAKGLESWQRLEPELVGWIYQPQQLGFGASPEQNGPWAFWAKKVKSPFPHALLNTIAIGESIVELAAKQSSLELGTLVELAIILQCLQRALATWFDKQVYDSKVSTKASISTYITFSVIWSQLASGFNNSTKSGEQLANACFQVTLQILRAFSQREYFPLYGGIFASFDGKSLRHTLEYLDEPLRRVEGTQAKARILTLLGYSMRAVGAYERSILLHKEALEIARLEDDKACEVANLNHISRNYVSQKNYQEAINYSQRALIMARQAGERQGEANALANLGYSEVFQARQLEDVEPEVYESAIGYLEQGLLLSERLGDRQSQAFCSSSLGIAKIALENSESAIEYLLKGWQAAQFSGDLYLQGLNLAYLAQAYYSINQLEKAIFAGSLGMYTLEQIGAMEWRQSAGLLTILRGQMGAEAFKESLGKSRGSIIPAIGVDGYDYIPELLEKYQQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0J5</accession>
    <name>A0A2G4F0J5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3288 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55276">
        <property type="protein sequence ID" value="PHX55276"/>
        <property type="gene ID" value="CP500_011555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021705">
        <property type="entry name" value="DUF3288"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11691">
        <property type="entry name" value="DUF3288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="11639" checksum="2D4237FFFE031D61" modified="2018-01-31" version="1">MDSVEKTQDQQHPQYRRDRTTVDTLLAGETTDHNLSELARLIIRYRGFPGARDIQRDLKKVLQQWNHTEETLYEQTRKIHAQGEVYRKQKSDQEDWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0M4</accession>
    <name>A0A2G4F0M4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55007">
        <property type="protein sequence ID" value="PHX55007"/>
        <property type="gene ID" value="CP500_013070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="342" mass="37655" checksum="2405E92D623613ED" modified="2018-01-31" version="1">MSKFDKIFNSENTSEASLSSEESLAAVALVAALANSPDTDADILESILWESEIFAEYSEDDLSTMLEKLAGIATEDGLGALFNTAWGSMPDELVLDTFAMTVAMFVVDGEVSDKHQLFLKEFQQALGLEDEEAEEIIEEVITAYSEEDGEFSEEDGEFSEEDGELYESPKGYFTVPIPVYEQKGGKIDEEEGSLAFSDDFGVLLKIDYFPIAGEVAELVESVGEAAYLSSFLNNYIDGAILAKFPNSKLLHTESLEDEEAYFAVVDMPGGATISVQEKLDPVTRLNAYRGFLAFIAEDVCYTVSSQRVYQEADELGSLESEVETMMDKILEFIETIEFGAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Q6</accession>
    <name>A0A2G4F0Q6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55335">
        <property type="protein sequence ID" value="PHX55335"/>
        <property type="gene ID" value="CP500_011360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="44"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="211" mass="23470" checksum="A400ACEFBFF7AE52" modified="2018-01-31" version="1">MSQVNLWSSAAHALWYLAKADSIPHRTEGEAVLLGEVPKTVKRILDVGTGDGRLLGLLKCDRPNVASVAIDFSPTMLEKVRIRFAEDSTVTVIEHNLDDSLPDLGKFDAVVSSFAIHHVTDNRKFSLYTEIFNILEPGGIFCNLEHVASATPALHQKFREALGIGDTPDDPSNKLLDVETQLRWFKEIGFTDVDCYWKWLELALLVGVKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0S8</accession>
    <name>A0A2G4F0S8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55057">
        <property type="protein sequence ID" value="PHX55057"/>
        <property type="gene ID" value="CP500_012905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="64"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="302" mass="33721" checksum="83F30013CBBB0B9C" modified="2018-01-31" version="1">MPDSEQSAAIPQPSDDKATKETSPLTEFVVQFWGVRGSIATPGGKTIRYGGNTSCVEMRLGKKRLIFDGGTGLRVLGLNLLRQMPVEAHMLFSHTHWDHIQGFPFFTPAFIPGNCFHIYGAIAPDGTTIKQRLSDQMHHPNFPVPIQVMQSDLKFNDLTPGDIVELDDVKIETALLNHPNTAIGYRVTWQGHTAVYCTDTEHFPDRLDDNIVHLARDADVLIYDANYTNEEYHDFKSPKVGWGHSTWQAGVEVAKAARVKKIVMFHHDPSHDDNFLDRVEADVQAVFANSCLAREGMSIAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0U2</accession>
    <name>A0A2G4F0U2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55067">
        <property type="protein sequence ID" value="PHX55067"/>
        <property type="gene ID" value="CP500_012655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="274"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="507" mass="56090" checksum="8C3D5CD2F6BA948B" modified="2018-01-31" version="1">MHYQVDAAQIGGQIYQIIATSSDGETLLQIAHTLGAACQADYCFVTAVTDNQIAIPNAGWPILGDRTNSTVISDAAAGLTETTRLNSPLSSIEHPIFANVLSDGEMIAISDIDNQTTNTPNSHLPFRAILASPVRFGGAINGMIMLGKWQPHQWSATSQQCVELASDAIASAIAHIQKNQEIANLNQQLQRQATHENLLGSVAKELNTNLEIPEILQQVIIQNQTIKDLQALVKDSMSQLEQSLDIQGQLYEQSANQLDQLRKWKQIKDDFLDCVNHELRTPLTIMNLAIVMLKQAEQRPESRAKYLDILDQKCIQEIGLIEDLLAVKQFESKQVPICLLQINIKHLIQDLARDFEKKWEDKGLALTVELPQSLPALKSDRDSLNRILLEMLVNAGKYSAFGTTIVLHVSEVAGRIVVSVSNLGRGILADDLPHIFEKFYRGTGVTQEVIPGMGLGLALVKYLVKHLNGTIEVDSRPSENSEGDELWRTSFTLTLPQFHEKLSSLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0U4</accession>
    <name>A0A2G4F0U4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55380">
        <property type="protein sequence ID" value="PHX55380"/>
        <property type="gene ID" value="CP500_010920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="100" mass="11719" checksum="0621801743681682" modified="2018-01-31" version="1">MPLLQCPTAMLLLSNFGVGLFCYLKALLANLLGKERGPPNEKARKLLYFASLGILAEFSTYQFIFIFFLDYKLILQYYFYIKRYKNKTKVYFCQNLGCEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F133</accession>
    <name>A0A2G4F133_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55448">
        <property type="protein sequence ID" value="PHX55448"/>
        <property type="gene ID" value="CP500_010735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="13019" checksum="4266A17F02AC27CA" modified="2018-01-31" version="1">MQLEDYFDFQRPDDIRVKGTRIGIETILYDFIHRARTPEQIAQIYPSLNLEQVYATILYYLHNKEAVSNYIADWLEWSHQQLKAQELNPSPSAIRLRKLRAEREVIQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F134</accession>
    <name>A0A2G4F134_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoenolpyruvate synthase</fullName>
            <ecNumber evidence="6">2.7.9.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Pyruvate, water dikinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_010745</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:11364"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.2" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55463">
        <property type="protein sequence ID" value="PHX55463"/>
        <property type="gene ID" value="CP500_010745"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPDK_N" evidence="11">
        <location>
            <begin position="16"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="10">
        <location>
            <begin position="403"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="12">
        <location>
            <begin position="538"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00021623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="822" mass="90725" checksum="23F0131EACF49FD7" modified="2018-01-31" version="1">MDHLYWLDKIQSLERDVVGEKAFYLSCLMQENHPVIPGFVVPAKTFWQFLESINWLEPLFADWPNSSLHLNVDEPKQLQAIARSIRRQITSTKLPDSLLSTLESAVCQLNAKALIFRPSLTSRHPNTAGILESQVVCPEPLAIEVGLKQAWAELFRAQKLFYWQRCGMNIREINPAVLVQPLSSAIAAGSLETKRGEAWEIQATCGLGMSLARGETIPDYYQVQPETGEVKIQRLGYKTLAYNLKIGGLDSGEKSSIGNFDALPIPDSKFPMPNSAGSCLDVCILGERAQSEYVLSQDNLQKLIDLSKKARAEFDSELTLEWTMNQSTECDEPEFYFTQVCLLKNQKATQTWENPIALSNQNAIAPGRNPAVLKGLAAASGKVKAIAQVMTNSHPEDAEFLAGGILVARAIPPHWLPWVKVAAGIVSEQGGMTGHGAILARELGIPAVVGVAGATRAIETGDSVWLDGDTGEVFASAQIQATPTDDRNYDQTANNADLSSQAAKISIAHYQFPTAARSHLDPKSPPPESAQYLASAPTATQLLVNVSQSNSIDRLRNLPIDGIGLVRSELMAMEALEGQNPQLWLKNGWESEFVERMATQLSLFAAAIFPRPIFYRSLDLRESGAHGSFSYTFEPELFDWELKVLKKVCDSGYTNINLILPFMRSVEEFVFCKQRLETVWKQRPVEFKLWIMAEVPSVLFLLPDYVKAGVQGISIGTNDLTQFMLGVNRNSTDMASAFNGRDRPMMRAIEQLIVQAKVAGIPCSICGDAPALYPEMIESLVLWGISSISVNVDAVERTYKAIARAEQRIILQAARSIIKNNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1H2</accession>
    <name>A0A2G4F1H2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannose-6-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55317">
        <property type="protein sequence ID" value="PHX55317"/>
        <property type="gene ID" value="CP500_011475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005976">
        <property type="term" value="P:polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001538">
        <property type="entry name" value="Man6P_isomerase-2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01050">
        <property type="entry name" value="MannoseP_isomer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MannoseP_isomer" evidence="1">
        <location>
            <begin position="13"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="14506" checksum="3BF526BAED4F2CBA" modified="2018-01-31" version="1">METVETIETIDTRTETRYWGSVTIIDAGDRYKINRIELKPGHHISTQMHYHRSEHWVVVSGTAKVICDDKETILMQKQSTYVPMNTPHRVENPGVIPLVMIEIQNGEYLGDDDIIRFPQDTHEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1L0</accession>
    <name>A0A2G4F1L0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3352 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55650">
        <property type="protein sequence ID" value="PHX55650"/>
        <property type="gene ID" value="CP500_009565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021787">
        <property type="entry name" value="DUF3352"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11832">
        <property type="entry name" value="DUF3352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="578" mass="63974" checksum="286F658886D9DC0F" modified="2018-01-31" version="1">MKLRSLFSFLIAGVLALLALSSGGFYWLTTHTPLNLLNGGPTTTPAAAVFVSKQAPLLVSMLVNPDRIESLRQVFATPAERSRSHAEFEQIKKSLLANTDLDYSRDIQPWIGDEITFGITTPDIDRDRKNGQQTGFLLALSSQNADRSQQFIDSYWQKQSIATKSVQFEQYKGVKLTYKQLSKIHQKSQPISALNRLNLPSSNLPSSFATALISDSSNSENNHNFVLFANSPKVLRDAIDNVQVANLNLQNTPEYQKALQQLNQGRIALAFVNIPQPETDKKPQLSLNSLAVAVGVNRRGLVAQTALVTSRENTVIPTLSEPVQALQYIPSASPFAVASTDLSNFWTDFSSAMSTNPEVSKLADRTLADIQTAWGINLPQDIFNWVKGEYALAVLPGSSNSSDWIFAAETSADSQKAIARLDEIARSKEYSIGSFTLRNQKITAWTQLTTSPNYDNENKRKSAIQTEAKGVRATVGKYEIFTTSVEAMDEALKAAETGSLMANQDFQTSIEPLPTSNDGYFYLDWPSSRRIWEKQIPLLRLIELSARPFFDHLRSLTITSTGETAGIRKATIFMRLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1L1</accession>
    <name>A0A2G4F1L1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55628">
        <property type="protein sequence ID" value="PHX55628"/>
        <property type="gene ID" value="CP500_009870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="146" mass="16231" checksum="7C32E397F1E7C768" modified="2018-01-31" version="1">MRDKGISEILITGFAVGMLWDLVTTFLGVVSIVAGPKFSISLNNIDTNTFGVCGIAVVSTVIVFCFNLLTTNVWKEAREGQWTLVAPWFLCVVFDFFTSLAGNYKFILPGRQNEIAVIGVIVFTTLLTTISPMAVRYLMMDYDKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1L2</accession>
    <name>A0A2G4F1L2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CRISPR-associated endoribonuclease Cas2</fullName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">cas2</name>
        <name evidence="11" type="ORF">CP500_011200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, forms a heterotetramer with a Cas1 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55357">
        <property type="protein sequence ID" value="PHX55357"/>
        <property type="gene ID" value="CP500_011200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09725">
        <property type="entry name" value="Cas2_I_II_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01471">
        <property type="entry name" value="Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021127">
        <property type="entry name" value="CRISPR_associated_Cas2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019199">
        <property type="entry name" value="Virulence_VapD/CRISPR_Cas2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34405">
        <property type="entry name" value="PTHR34405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09827">
        <property type="entry name" value="CRISPR_Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032582">
        <property type="entry name" value="Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01573">
        <property type="entry name" value="cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="5 9 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR032582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10624" checksum="5FD7CFE40637FA48" modified="2018-01-31" version="1">MHILISYDISEDKRRTKIHKMLKSYGQWMQYSVFECADLTETQYAKLRSRLNKVIKPNEDSIMFFPLCACCQGKIERIGGVVPADRTIFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F203</accession>
    <name>A0A2G4F203_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aquaporin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_008865</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55790">
        <property type="protein sequence ID" value="PHX55790"/>
        <property type="gene ID" value="CP500_008865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45724">
        <property type="entry name" value="PTHR45724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="236" mass="25090" checksum="1404449134B137C9" modified="2018-01-31" version="1">MFKSVSKTASSLFSPECRREAIAEFLGTFILVFAGTGAVMVNKISQGAITHLGISFVFGAVVAAMIYATGHISSAHLNPAVTLAFWTSGFFPKYKVLPYILAQCAGAIAASQLLLMTLGEVANLGATVPLNGNWLQSLILETVLTFILMFVILGSGLDRRAHIGFAGIAIGLTVALEAAFMGPITGASMNPARSIGPALIGGIWEHHWVYWVAPIWGAQLAVAVYRELSNGFRDFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F259</accession>
    <name>A0A2G4F259_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">(R)-citramalate synthase</fullName>
            <ecNumber evidence="4">2.3.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cimA</name>
        <name evidence="11" type="ORF">CP500_010250</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + pyruvate = (3R)-citramalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19045"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30934"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from pyruvate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the alpha-IPM synthase/homocitrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.182" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55557">
        <property type="protein sequence ID" value="PHX55557"/>
        <property type="gene ID" value="CP500_010250"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00066"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043714">
        <property type="term" value="F:(R)-citramalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005675">
        <property type="entry name" value="Citramal_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43538">
        <property type="entry name" value="PTHR43538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00977">
        <property type="entry name" value="citramal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="10">
        <location>
            <begin position="5"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="567" mass="62161" checksum="2B1AFBB12675432A" modified="2018-01-31" version="1">MTNRLWIYDTTLRDGAQCEGLSLSLEDKLRIARQLDSLGIPFIEGGWPGANPKDVQFFWRLKEQPLTQAEVVAFCSTRRPGTTAANDEMLQAILSAGTHWVTLFGKSWDLHVIEGLKTTLDENLAMIQDTIEYLRSQGRRVIYDAEHWFDGYKHNREYAIETLQVAAKAGAEWLVLCDTNGGTLPHEVSQVVRDVAGIMETWDISESEIHPPQPPLVKGGRKVAQSPIANEGRNSKIQLGIHTHNDSGVAVANALAAVQEGVTMVQGTINGYGERCGNANLCSLIPNFQLKLGYDCIQDEQLIKLTQVSRSVSEIVNLAPDDHAPFVGLSAFAHKGGIHVSAVEKNPLTYEHLEPQKVGNNRRIVISDQSGLSNVLAKAKTFGIELDRKDPACRQILDKLKSLESQGYQFEAAEASFELLMREALGKRQPWFEITGFQVHCDKVGEDCAALATVKLSVNGTNILECAEGNGPVSALDAALRKALVNFYPAIAHFYLTDYKVRILDGGAGTSAKTRVLVEFSNGQDRWTTVGVSGNILDASCQAVVEGLEYGLVLENQEAIALVCRVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2D5</accession>
    <name>A0A2G4F2D5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55934">
        <property type="protein sequence ID" value="PHX55934"/>
        <property type="gene ID" value="CP500_008145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="92" mass="9884" checksum="0A8FF8FD54DC373F" modified="2018-01-31" version="1">MTDFRSDADGSASGQRAAESWLFSGDRGNYQVSDFLVDRPLTNSVNISSLGQQNVGLESNAQINSVVKTDGIMNWAIGKSVLTMGAIELPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2F8</accession>
    <name>A0A2G4F2F8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fe-S cluster assembly ATPase SufC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sufC</name>
        <name evidence="6" type="ORF">CP500_008095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55925">
        <property type="protein sequence ID" value="PHX55925"/>
        <property type="gene ID" value="CP500_008095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="10"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="263" mass="28982" checksum="6D5FBBF9270CE880" modified="2018-01-31" version="1">MIVENSQVVLSVRNLTANVEDTQILKGLNLEIKSGEIHAIMGPNGSGKSTLSKILAGHPAYTVTGGEITFLGQNLLELPPEERSLAGVFLAFQYPLEIPGVSNVDFLRVAYNAHRKHRELEELDAFDFQDLIEDKLDIVKMNAAFLDRSVNEGFSGGEKKRNEILQMALLEPKLAILDETDSGLDIDALKIVAGGVNQLSTAENCMLVITHYQRLLNYIIPDFIHVMEAGRIILTGPKELALELEERGYDWVVEEEAAGVGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2J3</accession>
    <name>A0A2G4F2J3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromophore lyase CpcS/CpeS</fullName>
            <ecNumber evidence="3">4.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cpcS</name>
        <name evidence="4" type="ORF">CP500_009315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CpcS/CpeS biliprotein lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.-.-.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55687">
        <property type="protein sequence ID" value="PHX55687"/>
        <property type="gene ID" value="CP500_009315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017009">
        <property type="term" value="P:protein-phycocyanobilin linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01459">
        <property type="entry name" value="Chrphore_lyase_CpxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018536">
        <property type="entry name" value="CpcS/CpeS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09367">
        <property type="entry name" value="CpeS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="198" mass="22184" checksum="5ED58F3F77C550D7" modified="2018-01-31" version="1">MDAMEFFRSSAGEWRSHRTTHHLAFRQAEMGDSNIQVTALGADDARVAEICHMHEVDPIRAAGGAFVTWHGSMAWDKDDENHKGSTVFAIVPDPENPRQGLMLRERGYAEIVPVAGRFEMDDEDGLLLITEYETMSSIERFWFANPNVRMRTSSVKRFGGFSTSTFCTEIRVEPDADAAKTAAEAQPVTTEFYSALGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F303</accession>
    <name>A0A2G4F303_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_007360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56115">
        <property type="protein sequence ID" value="PHX56115"/>
        <property type="gene ID" value="CP500_007360"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00796">
        <property type="reaction ID" value="UER00771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033320">
        <property type="term" value="P:UDP-D-xylose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="PTHR43078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="7">
        <location>
            <begin position="4"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="312" mass="35563" checksum="E7460A1C608D0547" modified="2018-01-31" version="1">MRILVTGGAGFLGSHLIDRLMAQGHEVVCLDNFYTGTKRNILKWLDNPYFELIRHDITEPIRLEVDQIYHLACPASPVHYQYNPVKTIKTNVIGTMNMLGLAKRVKARFFLASTSEVYGDPDVHPQTEDYRGNVNCIGIRSCYDEGKRVAETLSFDYHRQNGVDIRVVRIFNTYGPRMLENDGRVVSNFIAQALRNEPLTVYGDGSQTRSFCYVSDLVEGFIRLMNCDEIGPMNLGNPGEYTILELAQKIQHMINPGAEIIFKPLPQDDPKQRQPDITRAKTWLGWEPTVPLDQGLELTIKDFRDRIEGNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F357</accession>
    <name>A0A2G4F357_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1348 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56165">
        <property type="protein sequence ID" value="PHX56165"/>
        <property type="gene ID" value="CP500_006890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009783">
        <property type="entry name" value="DUF1348"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31757">
        <property type="entry name" value="PTHR31757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07080">
        <property type="entry name" value="DUF1348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="141" mass="17098" checksum="3DA30D9FE2E3E2AB" modified="2018-01-31" version="1">METKPPLPPFTLETAKAKVQAAEDAWNSRDPERVALAYTEDSQWRNRAEFFSGRAEIKAFLQRKWAKELDYRLKKELWSFTDNRISVRFEYEWHNDSGDWYRAYGNEQWEFAENGLMRRREASINDVLIQESDRKFRWKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F362</accession>
    <name>A0A2G4F362_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56200">
        <property type="protein sequence ID" value="PHX56200"/>
        <property type="gene ID" value="CP500_006740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM_fam20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014903">
        <property type="entry name" value="DUF1796"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08795">
        <property type="entry name" value="DUF1796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM20" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="749" mass="85131" checksum="C419C724A48F9154" modified="2018-01-31" version="1">MYRFQIIGHTKTGESIGIVGSTPELGLWDITKCLRLNTSADRYPLWYTDIDIQPSLDLGDRQKIEYKYVYIDANGIAAWEGFGFNRWIPIDPDHKSSKIIVDDGAFGYFQPYPFGYYEEPVVKIPSHKKSEGLKIAVIGSSVAKGQKAWMFKGWASQLAESLQEKYGHQVVNLSEAGANVSKTIARFPSVVAPEQPDVVIIALSLGNEGLAYCRPHERRGAQRRFESGLQQLVKMTRALGARPMLGGVYPHGNYNSEHYWLLRDTHQRMLNWGVPVLDWLGVLDDGEGRWKQGISFDPSHPNTIGHKLMYETIDLNLFAINKDELVREKQYFSKPKTVPVFLDNVDFQVSACLEEQSLRIINSSPNNYTIAPYWQAIQTALQRQAGLIPGIYIAKNVKSGTLPFFAVQENGTIETTVEIPPGADLEYTSAFNLFAPNNSQLLFYDGNLGILKLDDRHLWIINESDKEYNIQPMWKEVRHVLKAMPSGVYDDPLNPDAPFRTMMIGDGLESRVKAPPKSAVLFQYKCQLSEISRVAILPLGDRCAVRMMLYKMEYDGPAFPFDLTRTTNIGDVADAIENGFYDMWNPAFLHYSAEAGRIYHSKWSGLSFAHEVEDTDDPVNDMSPVFERMRDRYTARSGRFWYALKHCDKVLFVRTGIADRNGAIDLIHKLEYQCQGKPFQLLLLSPQSSDEFAGLDNVLHYNVEFNPDRMYDDLGHWMYCTDVMRGILESIGVSSKNLFWCPPKIPQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F364</accession>
    <name>A0A2G4F364_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55907">
        <property type="protein sequence ID" value="PHX55907"/>
        <property type="gene ID" value="CP500_008405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="90" mass="10497" checksum="F64E97E0E1C22AD6" modified="2018-01-31" version="1">MIVLPKLENLRDTLPIEGAVRIELVEGIPIFRASTTVKNRIEELLEKQQNFPLNPEEEQELNLYEEIDDYLSFVNRTVRNLFLGQIQPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3B9</accession>
    <name>A0A2G4F3B9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56252">
        <property type="protein sequence ID" value="PHX56252"/>
        <property type="gene ID" value="CP500_006490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="25509" checksum="4CFBB877285399D4" modified="2018-01-31" version="1">MTKIQLTVLTAAILILPFFAAVPLQAQNLSLLQRLLETRGCPGCDLFGASLSRADLFGVNLSGAILSRADLIEADLTGADLMEANLNNANMRNAFLTNADFTKADLSRADIRGANLENANLSESFLREASLQSSNLKCTNLSATKLGRTDLRDADLTGANLSGADLREADLSGANLSGVDLRNADLSDARLIKANLKDTNLCGARMPNKKISQRGCQVKKGEEKAIKMNNYCNYCPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3I5</accession>
    <name>A0A2G4F3I5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-xylosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_005945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56344">
        <property type="protein sequence ID" value="PHX56344"/>
        <property type="gene ID" value="CP500_005945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000514">
        <property type="entry name" value="Glyco_hydro_39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01229">
        <property type="entry name" value="Glyco_hydro_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600514-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="442" mass="50196" checksum="82ABC05D00B38A34" modified="2018-01-31" version="1">MQFTFKFPSIHKLLPICLAIVTVLLIIYLGPQRSIAQMRSNVTIDFGSPATGTISMSGILHGIDPTKPPDNLIKPLQPKLWRAGRLDIYDRVIASGAQFQLLVSDLWGYGSNPKGWPYQNYPAWEAFIRQLAQQNKGKKIIWDVWNEPDLRNPFWNGSREQFFETYKRAYKILRQELGPSAMIGGPSITNYNKEYLTAFLDYCKANKLEVNFLSWHELNDNNILFVDDHVIDAKRNFQQSASYRELKLQKIYVNEIVGNLAQYEPGEILGYLYNLEYAKADGACRACWDTTGAKKVSNCFNNTLSGMVTPNSFEPRAAWWAYKAYADGVNSRVLSQSDNDRVVALASKSNPEGKAQVLLGYFDRNYSSATTVTLNLRNLPQLGIQSGQKIRLKLEKIPNNQERAVQKLVTVKEESVSVVRNDLNYVIPNFNVHEGYLLTVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Q8</accession>
    <name>A0A2G4F3Q8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 2-epimerase (Non-hydrolyzing)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56400">
        <property type="protein sequence ID" value="PHX56400"/>
        <property type="gene ID" value="CP500_005670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="27"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="372" mass="41224" checksum="A7FCDB715E9CB238" modified="2018-01-31" version="1">MPESTHRICIVLGTRPEAIKLAPVIQQFKNSPSFDTQVILTGQHREMVEQVMRMFDLTADRDLAIMQHQQTLTDITCRSLQGLEDLFKELQPKIVLVQGDTTTAFAAALAAFYQKIPVGHVEAGLRTDDVFNPYPEEANRRLISQLTRLHFAPTELAAENLVRSGVLGEIHRTGNTVIDALLAVAKSKPECKIPNLDWNKYRTILATVHRRENWGEPLQGIARAFLQILDKFPDTALLLPLHRNPTVREPLQALLGDHPRVFLTEPLDYTELVGAIQRCHLILTDSGGLQEEAPSLGKPVLVLRETTERPEAISAGTAKLVGTDSEIIATAAADLLSNSDAYNAMAMAINPFGDGLAASRILKIVEEYFRVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3W5</accession>
    <name>A0A2G4F3W5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4058 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56473">
        <property type="protein sequence ID" value="PHX56473"/>
        <property type="gene ID" value="CP500_005115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025132">
        <property type="entry name" value="DUF4058"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13267">
        <property type="entry name" value="DUF4058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="262" mass="30264" checksum="A678D8048D4E7E68" modified="2018-01-31" version="1">MPSPFPGMDPYLEHPELWPGLHHWLIIEIARLLSPQLRPKYLVSVEVRIYETADDNLSIGIPDINVIQPKTTTELITSNVAVAARPTQPLTVNIPMLYQVREGYLEIRERGSQELITLIEILSPSNKRTGKGRQMYEEKREEILSSRTHLIEIDLLRRGQKMPVIGNEIDSHYRVLVCRGNRRPKADLYAFNVQNPMPAFPLPLRSGDTEPIIDLQELFTQIYDIASYDLKIDYRNWEVIPALSEADTIWADAWLRDRGLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Z6</accession>
    <name>A0A2G4F3Z6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56469">
        <property type="protein sequence ID" value="PHX56469"/>
        <property type="gene ID" value="CP500_005095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="237"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="495" mass="55432" checksum="5580043578DB3F8B" modified="2018-01-31" version="1">MTAVPLPRPSPQTADRPSGRNSIDVTPVFALKELVARLHRYQHNVQDMLSSLGFALRTFNNLNQFLELVPLVATRITDAEGGALVLFKPNGQVRFQQLHCQAGRQCQDMRKALEIATKQVTTGVGTGADFMSGTSGQTSNLDIQVSRFLGPDVHLFGAPILLNNLERGRLYVFSSDPQYLFTPGRQKLVRLVADQTAVAIAKDELNAKLAEKERLDRELEIGAEIQLRLLPRSCPKIPGVDVVARCQPASRVGGDYYDFIPADYDPIGKEDEGEYPPSLIKNLKSRIDKGRWSIVIGDVMGKGVPAGLLMTMTRGMLRAEVLNRHSPARILQHLNRVMHADLENSHRFVTLFYSEYDPKTRILSYSNAAHHPPLLWQAATNSIERLDTLEGMLIGLDADSRYQEAQVQLQPGDTIIYYTDGFTDAANQVGDRFDEDSLTEAFQWACHNYQNSEEILNYLFDRVHQFIGFGNQNGDDMTLVVLRVTRATEENHHDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F425</accession>
    <name>A0A2G4F425_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">nusB</name>
        <name evidence="8" type="ORF">CP500_005105</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NusB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56471">
        <property type="protein sequence ID" value="PHX56471"/>
        <property type="gene ID" value="CP500_005105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="7">
        <location>
            <begin position="108"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="210" mass="23453" checksum="80D6A5D15D415EAB" modified="2018-01-31" version="1">MKKARETARELALLGISQLPSNPELLEAKKLQDVVLAAIRTLTTEVQESLETAASEVQRGSDKLLSSEIRAPDIESARAMVREAVELTQTAINRLGSAMEFPEIIQLANQQDVRTYALQILAKVSANRPEIDELLKEALVDWQIERLPRIDRDIMRIAIAEILFLGLAEQVAVNEAVQLAKRYSGDEGYRFINGVLRRVVDRINAQAVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F475</accession>
    <name>A0A2G4F475_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56562">
        <property type="protein sequence ID" value="PHX56562"/>
        <property type="gene ID" value="CP500_004755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="17"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="264" mass="30251" checksum="CED1D5BCFA6C976C" modified="2018-01-31" version="1">MTAVVTTLKTSEIIYPSADGEPVAETYDHVYAILTTLEVLKQYLADRRATVLANQYLYYAQGFSKLRVAPDVMVIFDVEPGGRDNYKIWEEGQVPKVIFEITSPGTKSEDIINKKELYEGIEVQEYWLFDPRGEWISEQLRGYRLGEEGYELIRDNRSEVLQLRLEIEGKLIGFYREDNGEKLLIPDELASALQAERQRAEAERQRAEAERQRAEAESQRAEAESQRAEAESQRAEAESQRANELESLLASYRSQFGELPQDNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F478</accession>
    <name>A0A2G4F478_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EVE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56548">
        <property type="protein sequence ID" value="PHX56548"/>
        <property type="gene ID" value="CP500_004680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="1">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="150" mass="17425" checksum="2661986274316B20" modified="2018-01-31" version="1">MNYWLMKSEPDVYSITDLNSDKVSIWDGVRNYQARNFMREMSMGDLVFFYHSNTKIPGIVGLMRVIEANISDPTQFDMNSDYYDAKSTFDAPRWQTVKVEFVEEFATLISLDELKQEFSIDEILVVRKGNRLSVMPISEAAAEKILKMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4A0</accession>
    <name>A0A2G4F4A0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative toxin-antitoxin system toxin component, PIN family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56568">
        <property type="protein sequence ID" value="PHX56568"/>
        <property type="gene ID" value="CP500_004795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002850">
        <property type="entry name" value="PIN_toxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34610">
        <property type="entry name" value="PTHR34610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00305">
        <property type="entry name" value="TIGR00305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="15298" checksum="1E9AB1CC93E02705" modified="2018-01-31" version="1">MKIVVDTNILVSAILRGRMPKRVIQSIIDRPDCEWLVSLEILAEYKEVLLRPKFKLSQGVIEEWWEIFDTVTQLIEVEVEVDFPRDRKDAKFLACALAGNADFLITGDRDFTEVETLGNTKIVSVSVFLDKILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4E0</accession>
    <name>A0A2G4F4E0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56608">
        <property type="protein sequence ID" value="PHX56608"/>
        <property type="gene ID" value="CP500_004545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="31"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="222" mass="25534" checksum="7449CA1558A76B3A" modified="2018-01-31" version="1">MQTQVRHTVFELNQLIVPPGNKVRLQNVSWEMYESILEELGEGYAVRLAYYKGTLEIRMPLPKHEKAKSLIGYLVNVLLEELNIDCEVLGSTTFKRQDMQTGVEPDDCFYIQNQGAVRGKDRLDLTVDPPPDLAIEIDNSSQTSLNCYEALGVPELWRYDGEVLKIYRLQEGKYTESSTSQNFPDFPIIDLIPQYVDRSKTEGRSPTIRAFRAWVREQLQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4K1</accession>
    <name>A0A2G4F4K1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56417">
        <property type="protein sequence ID" value="PHX56417"/>
        <property type="gene ID" value="CP500_005255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="98" mass="10727" checksum="1747FD280290B7A0" modified="2018-01-31" version="1">MSIYVGNLSYQVTSQEITSVFAEYGTVKRVHLPTDRETSRPRGFGFVEMSTDAEEDAAIAALDGAEWMGRDLKVNKAKPREDEGNRGGGNRGGGRGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4S5</accession>
    <name>A0A2G4F4S5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56784">
        <property type="protein sequence ID" value="PHX56784"/>
        <property type="gene ID" value="CP500_003370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="51"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="25701" checksum="360D0A6A25A671A7" modified="2018-01-31" version="1">MTASIATIIETNITATSSQWTTATWEDYLAVRDDRKNDNIGLFFNCDRLLVIDMGKEGINHASINNLFTMLFYIWFSQAPGLIYSSLGGCLLEKPKKQAASPDLMIYIGSDYPTWQAGERRYINLKQWRVPNLVGEIADTTLTIDLDEKKYLYADLGIPEYWVIDVKGLRVFAFQLQSNGKYQECETSTALSGLPISLLNQTLERLNAETNGSAAMWFAQQIASLKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4V7</accession>
    <name>A0A2G4F4V7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Precorrin-3B synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cobG</name>
        <name evidence="5" type="ORF">CP500_004905</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56527">
        <property type="protein sequence ID" value="PHX56527"/>
        <property type="gene ID" value="CP500_004905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012798">
        <property type="entry name" value="Cbl_synth_CobG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02435">
        <property type="entry name" value="CobG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIR_SIR_ferr" evidence="4">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="3">
        <location>
            <begin position="93"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="3">
        <location>
            <begin position="203"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="4">
        <location>
            <begin position="344"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="3">
        <location>
            <begin position="425"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="566" mass="62584" checksum="09AE3009D5666280" modified="2018-01-31" version="1">MLVLSELPTCPGLFSGSRARDGILSRMRIPGGILNAQQCWAIADLVDNYSTGWVQITNRANLQIREIHSEIPPDVWQNLQELGLASRLVEVDPIRNMMASPTAGIDREQLLDTRPLVQAWDNHLQTHPELSELSAKFSVGFDGGELSSIRDRPNDILLAANRRGEWPFARTGEWPFARTTEICFRLHLNVNAENCGDTGILIQPSQCISVLAALTNEYLEYTKIQPRIKGKKPRLRHLLADWGVEGYLERVQQNLSFSLQLTSCNFANNRQDACSTKSEFDSGSECSCGVGILPARTFANNRQDACSTKSEFDSGSECSCGVGILPAHSISKKSIPNHQHLGIHPQQQSGLSYIGIALPLGKLESKQLRNLANLAQNFAGGTLRLTPWQNLLISDIPNSQLLQVKQQITDWGLHWSTTNLDSCLVACSGSSGCASAMTDTQSHAIEMVRDLEQKLQIDRPINIHFSGCEKSCAQHSPIDITLVGIQIKQGNETIAGYDIYAGKTDSPFGRQIFQGVSVAQISSSIAQMLRIYQQLRSPDESFGEFIDRSAIDKLQQLLNPKKQNHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F539</accession>
    <name>A0A2G4F539_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56858">
        <property type="protein sequence ID" value="PHX56858"/>
        <property type="gene ID" value="CP500_003010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="302" mass="33869" checksum="80AA98C15C4082D9" modified="2018-01-31" version="1">MDRIACMQSFVRAIELNSFSAAAREQQTTQPTISKQIAALEKYLGVQLLTRSTTHLSLTEEGKKYYQYCQQILETVAEAEASLTGKERATGTLRLGCPVLFGQMQIVPRLKAFIKRYPDVKIDLMMADHFVDIVEDGLDLLIRIGNRLDSSLIGDRIGTTRRVTVATTGYFEQAGEPKKPDDLVHHDCIVYTHLATGNEWHFQGTDGTIKVRVGGCFQTNSSVAIRSAVLSGLGIAVAPVWMFGDEIYRGDIKVVLEDYQPTPLQIHAFYRRSRFYPAKITCFIDFLAAEFKLDPWVSDYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5R8</accession>
    <name>A0A2G4F5R8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57065">
        <property type="protein sequence ID" value="PHX57065"/>
        <property type="gene ID" value="CP500_001950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="404" mass="42521" checksum="4A63B77F2052E027" modified="2018-01-31" version="1">MKNSQPHSLILWRQVGGVAALQGAITLTWMLYRLYLPQLLTGFGFPGFDRGITILEDTLAIAIEPCAGWLSDKQRHWMGTRFPLIVVATIVSSLLFMAIPAIFIFGDSVSPLRWILPVVLVAWSIAMAMFRSPAVSLLGQYATQTQLPQAMSFLVLVGGLVGATRPVAGEFILSLGPVFTFAIGSFVLLGAVAFLRSVNPDAAVSQLPSDTAISEKMAIAPLGVIVLTGIAVAWGSRAMGERILPHVFQTQIAGVDSKLLMAGFTLGLAVTSLLAGLIAVRLGNQRTLLGGLVATAVLLLVMVFSQSFAIVFVAVLAVIFTNSLITIGTVPFALSLVPGRRGGFGVGLYFGGFSLGMSLYSLVFVAPKAVPAVTTGIVGAIAFLVATACVIAGDRLKQTRSVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5T0</accession>
    <name>A0A2G4F5T0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">JAB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_001585</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57120">
        <property type="protein sequence ID" value="PHX57120"/>
        <property type="gene ID" value="CP500_001585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="113"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="243" mass="26399" checksum="FCE714B64D9174D3" modified="2018-01-31" version="1">MTYSLRIVDLPTSERPRERLMAGGPKSLATAELIAILLGTGQGKGKLSAVGLGQYILNQLSQHQRDPLAVLRDISVQELTQIHGIGPAKATGILAAVELGKRVFQSRPPDLAVVDSPQSAADALSQDLMWQSQERFAVVLLDVKNRLLGTQVITIGTATETLAHPRDIFREVIRQGATRAIISHNHPSGNLEPSPEDIALTRQLLAGAQCLCIPLLDHLILGNGDFRSLRQTTTLWEEYPQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Y5</accession>
    <name>A0A2G4F5Y5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57203">
        <property type="protein sequence ID" value="PHX57203"/>
        <property type="gene ID" value="CP500_001400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9308" checksum="75E89B863AD494D5" modified="2018-01-31" version="1">MKKQQFQNTQAPRPPDVKRMSVSLSADAAELLEWLATTQGITQIEALRKAIATEAYLHKEIKQGSKVLLLNSDKEVREVIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F604</accession>
    <name>A0A2G4F604_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase sigma factor SigF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_001315</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57190">
        <property type="protein sequence ID" value="PHX57190"/>
        <property type="gene ID" value="CP500_001315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="5">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="257" mass="29695" checksum="2DA31E9A73EA014D" modified="2018-01-31" version="1">MPTTATNELKSENSKLLREYQNSGSNEVRNQLVKLNIGLARKEVHHWLNQCDETYDDLLQVGCIGLIRAIERFDLSKGHAFSSFAIPYIRGEIQHYLRDKSPSVRFPRHWLSLERKSVSVIKDLQMQFNRNPQDSEVAAVLEISVEEWREIKLARLNREPLSLDAPVQDEDDGATCLGELVPDTKYRSFQLAQEDQIRVQQALSLLEKRTREILEFVFLYDLTQKETAERLGISAVTVSRRVKKGLDLLKEIMTKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F640</accession>
    <name>A0A2G4F640_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57209">
        <property type="protein sequence ID" value="PHX57209"/>
        <property type="gene ID" value="CP500_001440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SH3b" evidence="2">
        <location>
            <begin position="100"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="29036" checksum="D9443304A0EBD480" modified="2018-01-31" version="1">MSLKTSQIIIISLVGLSTAIGVAWATIQSGSMKLSNPPLTESAVSDKKTISAVPTTSPQSQKFQPQPAKNSPVESSLIPNISDQKVEPVFITPPDSGCKINMAVINDPNPPLNVRSHPQVTDSKIVGTLKNNTFVSVAETQNGWLRITDPVPGWIAKNRTESSCPNVRQQINFRPGGDEAIVKGRIIGGGSHSYIIRAAKGQTMTVRNRKQVFPQILTPDGKLLTGNPYKDNQTEWTGKMPVTGNYTFQLDSNFRGYEYEFSVKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F668</accession>
    <name>A0A2G4F668_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1817 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57284">
        <property type="protein sequence ID" value="PHX57284"/>
        <property type="gene ID" value="CP500_001195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014946">
        <property type="entry name" value="CRR6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35724">
        <property type="entry name" value="PTHR35724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08847">
        <property type="entry name" value="Crr6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="161" mass="19015" checksum="94D0CEDBC20AD5FB" modified="2018-01-31" version="1">MTIMISINADRINNLDLSPVHTVIDQWLAEGAIAQNEQQLQFEIEYPREEFDPREISEIPEVRLWFIRLDAYYPWLPFLLDWKVGELARYSAMLVPHQFHRTEGIQYNPEALEMFLMHKIFVLTDWLSQQGIPSKSKLMAMSQMLGYDLDDAFFDVILPHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6H8</accession>
    <name>A0A2G4F6H8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57325">
        <property type="protein sequence ID" value="PHX57325"/>
        <property type="gene ID" value="CP500_000660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="156"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="564" mass="63481" checksum="FE2C48DD80B9DEE0" modified="2018-01-31" version="1">MAGLLRASEEGLKIIDMVRRNLGWNKSEDIWCKVALTSKATLRRFWAQNRIRRETFIDICKAVGINNWEDIIERNDIKETELLLAAAIADIPLDNQTDRTFPLPENLPPVRNWVQRTKEIELLKTLITPPPLTNESPTLAPPLSKGGLGGVPIAISIVGLPGIGKTTLVSQLIRQLHTEKTPFTCAAWQSLQSATGKAPPCDRTIDSLLFTLSNGEITATTNAQNDCGKKTENLLKILRDQPCLLVFDRADTLLKAGEAKAAGYFADDCAEYAWLFKQLLETEHQSKILFTSRESLAELPSTVTREIQLNGLDRDSAISLLQSFNLTANAEELAEMGDRYSGHPKALQLVAALIRDDTEFQGNVGNFLHQRDWLLIRDIESAIDEMIARLSDGEQTCLSRICVYQTSEYPLSFAGISAQMPEVSKYELKENIILALKCRQLLYYDRHLKSYQLHPLVREKGEHLLSQNPENLRTAHSQAYSYYISIPLKPESEWQDIEDIKPLIRAHYHARQAGNLDAANKIISEVCEYLRQWNCAELVCGNIELPLLGEVKSFTEDLQQDSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6S9</accession>
    <name>A0A2G4F6S9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3119 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57435">
        <property type="protein sequence ID" value="PHX57435"/>
        <property type="gene ID" value="CP500_000425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021467">
        <property type="entry name" value="DUF3119"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35550">
        <property type="entry name" value="PTHR35550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11317">
        <property type="entry name" value="DUF3119"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="15422" checksum="4CDA8BEB3746B727" modified="2018-01-31" version="1">MTTTTSSSTPTNTIELEPSYAIPIVLVLFAVPLLFVQKWVSLPLSVFGLFLMYQAATIRLQFTPTDLDIYRSQNLIRQFPYREWQNWRIFWPAVPILFYFKEINSIHFLPVLFDRKMLQTCLEQRCPRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6T9</accession>
    <name>A0A2G4F6T9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_000985</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57247">
        <property type="protein sequence ID" value="PHX57247"/>
        <property type="gene ID" value="CP500_000985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="61"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="292"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="319" mass="36206" checksum="90BACB7D0B8EF0D2" modified="2018-01-31" version="1">MPTYTGISSEAFQHPLDRQAEAALRSVPGFDLIASKFVEFVYERPQFIYLMGNSIQVGPRQYASIYHIFRECVQALDVFPEPGLFVSQNPSVNSYALGKNQPYVVLNTGLLDLLDEAEIRVVLAHELGHIKCGHPTLNQMAMWAMSVASTIGEMTFGLGNMVGSGLIYAFYEWRRKAELSADRAALLVTDDLNSVMKTMMKLAGVSSKYASECSLQEFIRQSDNYQELDRDNLNQVYKFLLYNGGSGAMLSHPFPVERLRYLRDWESSEEYRQIKLGNYKRAVSEGAVDVKSQTPNSEAEALRRQIEELQREIDRRKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6V9</accession>
    <name>A0A2G4F6V9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57307">
        <property type="protein sequence ID" value="PHX57307"/>
        <property type="gene ID" value="CP500_000555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7866" checksum="ACBE5ADEEE4C560A" modified="2018-01-31" version="1">MARIANLEQARCLFHNKYGRGLIDIARIASFEQARCLFHNKYGRGLINWKVPKFGLKIVLIWPVLLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUC7</accession>
    <name>A0A2G4EUC7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_023145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000269">
        <property type="protein sequence ID" value="PHX53134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53134">
        <property type="protein sequence ID" value="PHX53134"/>
        <property type="gene ID" value="CP500_023145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="16341" checksum="90798CEE16B4FFBB" modified="2018-01-31" version="1">MFLFDSPESKSNENSWSRKLDKFVKANQHELAALAWGLFLERGEESEEILGIDIAETPRFVYCKKEAVEELNRKVKSHIQEILGVLNAHKPEKEVAIVAIGAGQIKLILFEPKPEPPICFEEAATDVDTLLARLEQQMVEYMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUF1</accession>
    <name>A0A2G4EUF1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000253">
        <property type="protein sequence ID" value="PHX53169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53169">
        <property type="protein sequence ID" value="PHX53169"/>
        <property type="gene ID" value="CP500_022935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="120" mass="13967" checksum="6AA3E5DDE65CA24E" modified="2018-01-31" version="1">MLQRIKLMPDYSCYPLWDRDDGGDIEPWELPLSEATIERLLNWQKIYDGIIDWDDPASAGFASAQEEIAFEREGVSLWKQLQKELGDEYEIVYFSQLQQRVVSHLGELEEIGIFQKAEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUJ4</accession>
    <name>A0A2G4EUJ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_023130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000268">
        <property type="protein sequence ID" value="PHX53136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53136">
        <property type="protein sequence ID" value="PHX53136"/>
        <property type="gene ID" value="CP500_023130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="223" mass="24643" checksum="5A10858B87CB8529" modified="2018-01-31" version="1">MNDPLNSPYPVPWEWITATHAKVSSTMGSGLRYYRSPSLVSTNGQYAAYSRIELQVQPEFSQCRVSSVMFVENLKTGELQTVAAASPLAESGFYATDETDMSGTIAILVPVAWNQTGSRVLAREFEALFNSSDMSDYAVIWDKNENYTYTVAPARSLYTHAVLLGWSQVCPGQVLFRAGNLGDRTWPLCAVDTNGETVVVNDDQPLVFGTQGSTDWIEPKTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV45</accession>
    <name>A0A2G4EV45_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <shortName evidence="9">HTPA reductase</shortName>
            <ecNumber evidence="9">1.17.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapB</name>
        <name evidence="12" type="ORF">CP500_021700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:35323"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:35331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53409">
        <property type="protein sequence ID" value="PHX53409"/>
        <property type="gene ID" value="CP500_021700"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016726">
        <property type="term" value="F:oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00102">
        <property type="entry name" value="DapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="10">
        <location>
            <begin position="7"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="11">
        <location>
            <begin position="140"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="(S)-2,3,4,5-tetrahydrodipicolinate binding" evidence="9">
        <location>
            <begin position="174"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="108"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>(S)-2,3,4,5-tetrahydrodipicolinate</name>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="275" mass="29584" checksum="DB72155E29C563DD" modified="2018-01-31" version="1">MANQLPIPVIVNGAGGKMGREVIKAIAKAKDLTLFGAIDHSPESLHADAGELAGCGPLEVPITDDLQGMLVLAAQEKQLGVMVDFTHPNSVYENVRSAIAYGIRPVVGTTGLSTEQIQKLAEFADKASIGCLIIPNFSIGMVLLQQAAVTASQYFEHVEIIELHHNQKADAPSGTAIQTAQMLAEMGKTFNPPQVEETEKLQGARGCLAEEGIRIHSIRLPGLIAHQEVIFGGEGQVYTLRHDTSDRACYMPGVLLSIRKVLELRSLVYGLEKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV61</accession>
    <name>A0A2G4EV61_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000201">
        <property type="protein sequence ID" value="PHX53415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53415">
        <property type="protein sequence ID" value="PHX53415"/>
        <property type="gene ID" value="CP500_021610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="12"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="383" mass="43123" checksum="5E0835536FD3FCA6" modified="2018-01-31" version="1">MKVSLVVSDLSGGGAIRAFLLAQILIKLNYEVEVIGFQFGKELYTIPPKNIPVCAIPGNNYPGFLISAQKVLKKIDGDIIYAVKPKPTSFGLSLLKKLETRRPVILDIDDWELSWFGGDEWKYHPSFKQLYRDICKKKGQLREPDHPLYVKWMENLVSRADAITVHTEFLKQRFGGVYLPNGKDTEMFDPAKYNSELSRERYGLSGYRILMFPGAPRPHKGVEDVLMALEQLNEPDLRLAIVGGSPYDDYDDRLMQQWGRWIIKLPRFPVEKMPEVVAAAHIVVVPQRDTLTAVAQFPLKLTDGMAMAKPVLSTRVGDIPAILGGTGYLVEPNSPAQISQKIQWIFQNLTAANFQGIKARERCVEKYSIQTMAPILSDIISGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV66</accession>
    <name>A0A2G4EV66_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000200">
        <property type="protein sequence ID" value="PHX53424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53424">
        <property type="protein sequence ID" value="PHX53424"/>
        <property type="gene ID" value="CP500_021595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="164" mass="19159" checksum="870C96AB2DF71A33" modified="2018-01-31" version="1">MLTHQRKPVSLSLVSTDLPLWSVVETAGTLYQKDSDRFHLLLHEPAIVDRTFPDDSSEQISILPTATKPRLLWLEVSPYRVVMTMQGNGKYSYRHAWERGMYGLSRYWLQGDSLATPEQLRLRNFTRELTLTGKPEPGHLRLEYELWSQKVQLGRYILNLEIHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVA5</accession>
    <name>A0A2G4EVA5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000207">
        <property type="protein sequence ID" value="PHX53370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53370">
        <property type="protein sequence ID" value="PHX53370"/>
        <property type="gene ID" value="CP500_021830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="17775" checksum="7F0EC3745F4C88DE" modified="2018-01-31" version="1">MPDRTDWLVAAMLVVTYSAIGLPIGFWSGFLKIDVQTSWRTILGVTVGCLLSPGITEELFFRVLILPHKQENASGLMLWFWGCVSLALFVVYHPLNGLTFYPVGRETFLNPVFLLLAAVLGAMCAIAYLQSGSLWPAVAIHWLAVTVWLLILGGYRRLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVE1</accession>
    <name>A0A2G4EVE1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Malate dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 8" type="primary">mdh</name>
        <name evidence="8" type="ORF">CP500_021175</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LDH/MDH superfamily. MDH type 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000188">
        <property type="protein sequence ID" value="PHX53499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53499">
        <property type="protein sequence ID" value="PHX53499"/>
        <property type="gene ID" value="CP500_021175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01339">
        <property type="entry name" value="LDH-like_MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00487">
        <property type="entry name" value="Malate_dehydrog_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011275">
        <property type="entry name" value="Malate_DH_type3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01763">
        <property type="entry name" value="MalateDH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="6">
        <location>
            <begin position="15"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="7">
        <location>
            <begin position="158"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2 3">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="20"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="129"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="326" mass="35179" checksum="E3DB3B205058A072" modified="2018-01-31" version="1">MTSINFTNLNCPSTRVSIIGAGKVGSTLAQRVAEKNLADVVLLDIVEGWPQGIALDLMQARGAERHDRQIVGTNNYADTANSNIIVIAAGIPRKPGINREDLIKINAKIVTESAQQAIAHSPEAILIVVTNPLDVMTYLAWEATGLPKHRVMGMAGILDSSRFQTFIAMELGVSIAEINATVLGSHGDLMVPLPRYSTVNGIPIAQMMDAETIARLVDRTRNGGAEIVKLMQTSSAYFAPASSTCLMVESILLNQSRILPCSVYLNGQYGVQDLFLGVPCRLGYQGVEQVIELELSDTEKAAFMECGKLVRQSIEEAKAILNNAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVK2</accession>
    <name>A0A2G4EVK2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000246">
        <property type="protein sequence ID" value="PHX53197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53197">
        <property type="protein sequence ID" value="PHX53197"/>
        <property type="gene ID" value="CP500_022805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="163" mass="18950" checksum="EF2B293332452D04" modified="2018-01-31" version="1">MKTQYHDFLIRSWETCDRADAFHVIRDVLLEYGLKSEPFGADRDVYDVELHYHAKGGEFWVVEREGEIVGTAAYYPIERGNNAVEIRKMYILPKARKKGLGKFLLQELESKIVSRGFDEIWIETASVLKEAVKMYENSGYQPTIGVETQRCDRVYKKVLNCEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVT7</accession>
    <name>A0A2G4EVT7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmA</name>
        <name evidence="5" type="synonym">rpl27</name>
        <name evidence="7" type="ORF">CP500_020660</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53588">
        <property type="protein sequence ID" value="PHX53588"/>
        <property type="gene ID" value="CP500_020660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="96" mass="10230" checksum="7F6BD86FC9C89925" modified="2018-01-31" version="1">MAHKKGTGSTRNGRDSNSQRLGVKKYGGQVVKAGNILIRQRGTKVHPGNNVGIGRDDTLFAMIDGVVTFERKGKTRKKLSVYPVVVAAPVAEAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW05</accession>
    <name>A0A2G4EW05_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Family 2 glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53713">
        <property type="protein sequence ID" value="PHX53713"/>
        <property type="gene ID" value="CP500_019955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="308" mass="34823" checksum="5F42515BA65BA40A" modified="2018-01-31" version="1">MFFSVVIPTYNRIPILAKCLLALENQQFGNSVRDYEVIVVDDGSTDGTLEWLAANADELPHVRSIAQSHQGPAAARNLGIEDANGDTIIFIDSDLVVTEHFLQSHADALLQGYKDTDAVFTYGSVINTCNFDNPTSEPYKITDFSAAYFATGNVAIGRHWLIEAGLFDNRFQLYGWEDLELGVRLKKLGLKLIKCPAAVGYHWHPPFNLDQIPGMIDREIQRGRMGVLFYQKHPSWEVRLMIQMTWLHQILWGVLSVGGLLNERTMTPFLQWLIDRGNSQLALEIARIFLNWYNVKAVYAAYGELEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW43</accession>
    <name>A0A2G4EW43_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome hibernation promoting factor</fullName>
            <shortName evidence="2">HPF</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">raiA</name>
        <name evidence="2" type="synonym">hpf</name>
        <name evidence="5" type="ORF">CP500_019865</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with 100S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000158">
        <property type="protein sequence ID" value="PHX53744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53744">
        <property type="protein sequence ID" value="PHX53744"/>
        <property type="gene ID" value="CP500_019865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00839">
        <property type="entry name" value="HPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034694">
        <property type="entry name" value="HPF_long/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032528">
        <property type="entry name" value="Ribosom_S30AE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038416">
        <property type="entry name" value="Ribosom_S30AE_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16321">
        <property type="entry name" value="Ribosom_S30AE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Ribosom_S30AE_C" evidence="4">
        <location>
            <begin position="131"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="217" mass="24185" checksum="ACC364B93EDFFAAD" modified="2018-01-31" version="1">MKLVIQGKNLEITDAIREYVNQKVEKAVSHFQALTTEVDIHLSVARNPRINPKQTAEVTIYANGSVIRAEESTESLYASIDLVADKIARQLRKFKEKRQDNKTNSNAKTVAVVEELPVVADLIGDRTPELPAEVVRTKYFAMPPMTVQEALEQLQIIDHDFYMFQNAETGEINVLYERKSKSGYGVIQPRNAKAHGNSKNGKTAHNVAHEKSGAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW88</accession>
    <name>A0A2G4EW88_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000152">
        <property type="protein sequence ID" value="PHX53822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53822">
        <property type="protein sequence ID" value="PHX53822"/>
        <property type="gene ID" value="CP500_019450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="458" mass="50796" checksum="F31FC9AE66D207FF" modified="2018-01-31" version="1">MMGINWQRKAVGKLLVLLAAVLILGLTSCSKTNPDLPKSSNNSTSALTEVKKISEVSPPAGIQKLRHALEVYQPQVSILQPKPDQMLQDTYISVQLQVKDLPIFKDANLGLGPHLQVFLDNQPYQAVYDTNQPLELSDLEPGTHTLRVFASRPWEESFKNEGAFAQTTFHVFTKTQDNNPDRTLPQLTYNQPQDTYGAEPIMLDFYLTNAPLHLVAQENSQDEILDWKIRATVNGETFAIDQWQPIYLKGFKPGKNWVQLELIDEQGNLVKNAFNNTVRLINYQPLGQDTLSKLVRGELTAAETRGIVDRNYKPETPKLEPTPEPKPTPALETPIVNPSPAVPETPVAKPSQEPKIAPEVEPIPVTEPTATATPEPETPKIVEPIPVTEPTATATPEPETPKIVEPIPVTELEKPSPNLPPTSPETIVKSTTELTLPEQTISEPENQPQSEQKVEFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWM6</accession>
    <name>A0A2G4EWM6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Photosystem I P700 chlorophyll a apoprotein A1</fullName>
            <ecNumber evidence="20">1.97.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">PsaA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20 23" type="primary">psaA</name>
        <name evidence="23" type="ORF">CP500_018905</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="23 24" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 20">PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.</text>
    </comment>
    <comment type="function">
        <text evidence="21">PsaA and psaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>hnu + oxidized [2Fe-2S]-[ferredoxin] + reduced [plastocyanin] = oxidized [plastocyanin] + reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:30407"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10039"/>
            <dbReference type="Rhea" id="RHEA-COMP:10040"/>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <dbReference type="ChEBI" id="CHEBI:30212"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
            <dbReference type="EC" id="1.97.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <text evidence="20">PSI electron transfer chain: 5 chlorophyll a, 1 chlorophyll a', 2 phylloquinones and 3 4Fe-4S clusters. PSI core antenna: 90 chlorophyll a, 22 carotenoids, 3 phospholipids and 1 galactolipid. P700 is a chlorophyll a/chlorophyll a' dimer, A0 is one or more chlorophyll a, A1 is one or both phylloquinones and FX is a shared 4Fe-4S iron-sulfur center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="20">The PsaA/B heterodimer binds the P700 chlorophyll special pair and subsequent electron acceptors. PSI consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The cyanobacterial PSI reaction center is composed of one copy each of PsaA,B,C,D,E,F,I,J,K,L,M and X, and forms trimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="20 21">Cellular thylakoid membrane</location>
            <topology evidence="20 21">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 20 21">Belongs to the PsaA/PsaB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.97.1.12" evidence="20"/>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53929">
        <property type="protein sequence ID" value="PHX53929"/>
        <property type="gene ID" value="CP500_018905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00458">
        <property type="entry name" value="PSI_PsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006243">
        <property type="entry name" value="PSI_PsaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001280">
        <property type="entry name" value="PSI_PsaA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020586">
        <property type="entry name" value="PSI_PsaA/B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036408">
        <property type="entry name" value="PSI_PsaA/B_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30128:SF61">
        <property type="entry name" value="PTHR30128:SF61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00223">
        <property type="entry name" value="PsaA_PsaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002905">
        <property type="entry name" value="PSI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00257">
        <property type="entry name" value="PHOTSYSPSAAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81558">
        <property type="entry name" value="SSF81558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01335">
        <property type="entry name" value="psaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00419">
        <property type="entry name" value="PHOTOSYSTEM_I_PSAAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 20 21" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 20 21" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="15 20 21" id="KW-0157">Chromophore</keyword>
    <keyword evidence="13 20 21" id="KW-0249">Electron transport</keyword>
    <keyword evidence="17 20 21" id="KW-0408">Iron</keyword>
    <keyword evidence="18 20 21" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12 20 21" id="KW-0460">Magnesium</keyword>
    <keyword evidence="19 20 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 20 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 20 21" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="11 20 21" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="9 20 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 20 22" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 20 21" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="545"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="604"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="678"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="741"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="587"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="596"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="20">
        <location>
            <position position="689"/>
        </location>
        <ligand>
            <name>chlorophyll a'</name>
            <dbReference type="ChEBI" id="CHEBI:189419"/>
            <label>A1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="20">
        <location>
            <position position="697"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>A3</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="705"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>A3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="706"/>
        </location>
        <ligand>
            <name>phylloquinone</name>
            <dbReference type="ChEBI" id="CHEBI:18067"/>
            <label>A</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU003775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="PHX53929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="764" mass="84364" checksum="C8319FD41FE4CB6B" modified="2018-01-31" version="1">MTISPPEREVKVRVVVDKDPVPTSFEKWSKPGHFDRTLAKGPKTTTWIWNLHANAHDFDSHTSDLEDVSRKIFSAHFGHLAVIFVWLSGAYFHGAKFSNYEAWLTDPTAIKPSAQVVWPIFGQEILNADVGGGFHGIQITSGLFQLWRANGITNSYQLYCTAIGALVMAALMLFAGWFHYHVRAPKLEWFQNVESMMNHHLAGLLGCGCLGFAGQQIHVALPINACMDAIDAGSPLTVGGKLIKTVADIPLPHEWLFNAGLMADIYPSFAQGLTPFFTLNWGAYSDFLTFKGGLNPTTGGLWLSDTAHHHLALAVLFIIAGHMYRTNWGIGHSMKEILENHKGPFTGEGHKGLYEVLTNSWHAQLSINLAILGSISIIVSHHMYAMPPYPYIATDYPTQLSLFTHHMWIGGFLIIGAAAHAAIFMVRDYDPAGNVNNLLDRMIRHRDAIISHLNWVCIFLGFHSFGLYVHNDTMRAFGRPQDLFSDTGIQLRPIFAQWVQNIHALAPGNTAPNAMEIVSHAFGGGAVVVGGKVAMMPIELGTADFMIHHIHAFTIHVTVLILLKGVLFARSSRLVPDKASLGFRFPCDGPGRGGTCQVSGWDHVFLGLFWMYNCISIVIFHFSWKMQSDVWGTVDADGTISHITGGNFAQSAITINGWLRDFLWAQASQVIQSYGSALSAYGLMFLAGHFVFAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPSIQPRALSIIQGRAVGVAHYLLGGIVTTWAFFLARIISVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWQ6</accession>
    <name>A0A2G4EWQ6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperonin GroEL</fullName>
            <ecNumber evidence="6">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Chaperonin-60</fullName>
            <shortName evidence="6">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">groL</name>
        <name evidence="6" type="synonym">groEL</name>
        <name evidence="9" type="ORF">CP500_019165</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000146">
        <property type="protein sequence ID" value="PHX53870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53870">
        <property type="protein sequence ID" value="PHX53870"/>
        <property type="gene ID" value="CP500_019165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="478"/>
            <end position="480"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="557" mass="59166" checksum="481C995AA8FF9E30" modified="2018-01-31" version="1">MTKIIAFSDKSRRALERGVNQLADAVRITLGPKGRNVLLEKKFGAPQIVNDGITVAREIELEDPLENAGARLIQEVASKTKDIAGDGTTTATVLAQSLIREGLKNVAAGANPVALRRGIEKTIAHLVLEIAKLAKPVEGAAIAQVATVSAGNDEEVGEMIFQAMEKVTKDGVITVEESKSLLTELEVVEGMQYDRGYLSPYFVTNTDRMEVEYENARILITDKKISSIQELVPILEKIARAGQPLVIIAEDIEGEALATLVVNKARGVLNIAATKSPGFGERRKAMLQDIAVLTGGQLISEEVGLSIDTATLEMLGTARKITIDKENTIIVTGDEHKADVQKRIVQIRQQLEATDSDYDKEKLTERIAKLAGGIAVIKVGAATETELKDRKLRIEDALNATKAAVEEGIVAGGGTTLIHLITKIDAIRNTLDAEEQLGADLVAKALEAPLRQIADNAGVEGSIVIERVRVSEFNIGYNALTDVYEDMIAAGIIDPAKVVRSALQNAGSIAGMVLTTEAVIVEKPEPKKAGGDMGDMGGMGGMGGMGGMGGMGGMGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWV1</accession>
    <name>A0A2G4EWV1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5-oxoprolinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000133">
        <property type="protein sequence ID" value="PHX54001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54001">
        <property type="protein sequence ID" value="PHX54001"/>
        <property type="gene ID" value="CP500_018520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase_A" evidence="1">
        <location>
            <begin position="19"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_B" evidence="2">
        <location>
            <begin position="484"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="996" mass="106980" checksum="E773403F8B5DB188" modified="2018-01-31" version="1" fragment="single">PCPPPMPYAPCPIPNDQFPKLMFMQSNGGLVDAAQFQGKNSILSGPAGGIVGAVQTSKKAGFDKIITFDMGGTSTDVAHFNGEYEREFETEIAGVRLRSPVMAIHTVAAGGGSIVFFDGARYRVGPESAGANPGPACYRNGGPLTVTDCNVMLGKIQPDFFPKVFGLNGDLPIASDVVKQKFVQLAGEIGGERTAEQVAEGFLAIAVEKMANAVKKISLQRGYDVSEYTLCCFGGAGGQHACAIADALGMKRVFIHPYAGVLSAYGMGLADVRVMRESAIEQQLSLELITDLHHILAQLEAEGKRELNRRDAEGAGEEEEIFVIRKLHLKYQGSDSVLAVNFDANIEVMQAEFEAAHRQRYSFIMSEKALIVEAVSVEVVETMDVPEISTISSDCGTGILPVQAISTVQMYVAGEWRETPVYKRENLRSHNSITGPALIVEATGTNAIEPGWEAEITENNDLILNRRSTVMNADNTRLSAVESDPVLLEIFNNLFRAIAEQMGITLQNTSSSVNIKERLDFSCAIFDQNGQLVANAPHIPVHLGSMSESISALISAKATTIKPGDVYVSNNPYNGGTHLPDITVITPVFDNSNSLVLFYVASRGHHADIGGITPGSMPPNSTSVTQEGILMDNFQLVCDGKFCSQKLLELLNIGEYPVRNPAQNLADLQAQIAANQRGAEELLKMVEHYSLETVQAYMGFVQDNAEESVRRVIDVLQNGEFTYAMDSGGQIKVAITIDKSTRSAKIDFTGTSPQQTNNFNAPAAVCKAAVLYVFQTLVDDDIPLNAGCLKPLEIINPEGCMLNPKYPAAVVAGNVETSQNITDALYCALGVMAASQGTMNNFTFGNQRYQYYETICGGSGAGADFDGTDAVQTHMTNSRLTDPEVLEWRFPVLLESFAIRANSGGNGCHRGGNGVVRRMRFREAMTAGILSGRRVISPCGLNGGEAGKVGRNYVERVDGKVEELGSTATVEMQAGDVFVIETPGGGGYGTIVATVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWW2</accession>
    <name>A0A2G4EWW2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0102 protein CP500_018420</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_018420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0102 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54011">
        <property type="protein sequence ID" value="PHX54011"/>
        <property type="gene ID" value="CP500_018420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00048">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003509">
        <property type="entry name" value="UPF0102"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34039">
        <property type="entry name" value="PTHR34039"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02021">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="22787" checksum="4587AB8B4ADF4ACB" modified="2018-01-31" version="1">MSGDSSELNFTRKRDRLVVSNDSNSPPSPNSRDIGTFGENLVAEWLQQQGWEILHRQWHCRWGEIDIIALGTDEECEIKETHQDSQFPIPHSQCPMPNAPFPTLAFVEVKTRRRGNWDADGMLAVTVAKQAKLWQTAEIFLSNHPDLANHSCRFDVALVRCEPIGRKNHKILPSTAANSQVSLTSSNRFTLQQYIRSAFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWY9</accession>
    <name>A0A2G4EWY9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipid carrier-dependent glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000128">
        <property type="protein sequence ID" value="PHX54065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54065">
        <property type="protein sequence ID" value="PHX54065"/>
        <property type="gene ID" value="CP500_018175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="689" mass="77390" checksum="3805FA6B6C5737D6" modified="2018-01-31" version="1" fragment="single">LSPSHTLPLSPSSFFWAIAFGISLGLSILVKHTTVLFLFTPIVWLAVGTFRQKAWGRSAQLAGALLLSVVVFGPWAKTNWLLILTGGKRATFDSAMAEGDPALNTINAWIYYGQHLPEHISWPLLLIPLVGFLLYFWRNRQDSSSILYFKSCHWLAVFWVGAYLINSVNINKDDRYVLPYLPIVAIFLAYCLTLWPQRWGQQIRWGTIGLAIIAMLFHMWPLGGSLGHNSVQLVSPGNSSYPYLGKEWPHREVIAEIIDTEPYLQSTLGVLPSTPEINQHNLNYYGALAKFQVYGRQVGTSVAEVPQDVRSLSWFVTKTGPQGSIRQRIKKAQNAAVAAIEKGDKFQLQKSWLLPDNTNLNLYRKRWRAVEIQPLNEVRSQVQLEQVTLPSKAVPGVPLPVTYIWSGPWQQLQSGLVLLTWKNRLASDIQQPGQTYRILHDRAIAQATLHPGILEADKFAVGFRVVDRTAMLPPANLAPGSYNLEATYLNRKTGETYLINVPTVSVKIEAKSLDMRSQAKPGNEDNTDKPELDLVTQLRTMASNLPKGLPGLKPVFEQIGRINQYDPIQDYTVQAEQSLEYRLKQEPNNLELAYGLAFSRALQQNVKGAIAALEKVTQLDSQNPYAFGYLAFIHIYAWHPKAAETALKPALVLNSNLPEIRVLNGVARLMQGNLIEAWQDLQYLKKLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWZ7</accession>
    <name>A0A2G4EWZ7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA polymerase subunit sigma-70</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000133">
        <property type="protein sequence ID" value="PHX53998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53998">
        <property type="protein sequence ID" value="PHX53998"/>
        <property type="gene ID" value="CP500_018505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="215" mass="24700" checksum="8F55B0D54EF0FDAD" modified="2018-01-31" version="1">MQTPNFSEFNHPVVKSLFHHSDQELLTLFQTHPDQGKFFTAIFCRYAQIVHSLIRHSVRSPVQADYLFAHTWLHIYHELRGLDLRHETQESDGGNLSLQNWLINVTAICINQAELPPVETIHYSLQSAPPPLWCYVKQALELLAPLPRLVVLMAQTFRWSETRIAAYLQAEGEAISPAQVKALLQKGYQTLESNLPQDIRAIYLDQNLDYQEALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX04</accession>
    <name>A0A2G4EX04_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_018140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000128">
        <property type="protein sequence ID" value="PHX54059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54059">
        <property type="protein sequence ID" value="PHX54059"/>
        <property type="gene ID" value="CP500_018140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="9"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="189" mass="21021" checksum="F429E505EB1C4BD1" modified="2018-01-31" version="1">MPESKPYQPLLLRLLHGVNAAIALLAIITAFLVYNTYDGRFGKVPVPQIADIIGIHGTFGKLLILGVMPAFALYSFHRGQKRLVQPDSFGKLTQFGKPIWWYSLHRIVNTLMLVAMTFSIASGSMVKEEWLPAGDLTQVWYYLHASGWIILVLCLAMHLLMSAKVGGFPLILSMFDFKKVKGNQAGEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXD8</accession>
    <name>A0A2G4EXD8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein phosphatase 2C domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000124">
        <property type="protein sequence ID" value="PHX54110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54110">
        <property type="protein sequence ID" value="PHX54110"/>
        <property type="gene ID" value="CP500_017880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="264" mass="28098" checksum="D82D32B1F323362F" modified="2018-01-31" version="1">MTNDSGLLTNWQVVAASVMGTSHSKRSQPCQDAHCWRLLPNGVLVAAVADGAGSATLAEVGAKIAVETVVETICRQSKMLPGDDAQWQVFLTAALQVARAAVEAEAATREVQARDLACTLIAVVATPELIAVAQIGDGAAVAGDNQGCAIALTIPPCGEYINETIFLISPNALETAQFHVRREKMAHLAVFSDGLQMLALKIPEGTPHGPFFAPLFRFSAQVQDESDAQQQLESFLRSPRVCDRTDDDLTLLLASCLSSEVQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXF7</accession>
    <name>A0A2G4EXF7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000150">
        <property type="protein sequence ID" value="PHX53837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53837">
        <property type="protein sequence ID" value="PHX53837"/>
        <property type="gene ID" value="CP500_019365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37953">
        <property type="entry name" value="PTHR37953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="311" mass="33107" checksum="001FE18489E8A62F" modified="2018-01-31" version="1">MANIDGTLGFDFLLGSPNADLIRGFAGNDTIQGLGGNDLIFGDRENDLLAGNEGADTLAGGQGSDTIYGGQGDDVINGDRGQDLLIGGERKDILTGGAGDDLFVIEQTVAASSITEADLITDFGNGKDQIVLTNGMKFSDLDISVSDNQTVMKDKNTGKYLGIFSGIINLSQSNFISLFGGIDAGQLLPISVNTIIGDRPLGLEVAKTPQEQAIGLMFRTELPDDRGMLFPIEPVRNVRFWMRNVFIELDMIFLREGVVQAIIPNVPPCLTENCPNYGPDVPVDGVMELRGGRAAELGLKVGDRIALGQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXG1</accession>
    <name>A0A2G4EXG1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000122">
        <property type="protein sequence ID" value="PHX54130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54130">
        <property type="protein sequence ID" value="PHX54130"/>
        <property type="gene ID" value="CP500_017760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013626369" evidence="2">
        <location>
            <begin position="22"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="554" mass="60451" checksum="8936D73BD11A45A7" modified="2018-01-31" version="1">MIRRYIPSISIHILKRTCATAAVLALTLGCSSTKPPNTVTSSGAIASAAQTQPPESLLAQNSKNPKQSVSASSCTQNDGFTEAVSFATQASNLAQSANSKEEWDEVAALWVQAVAWMQAVPPSSPKRAFAEKKVVEYMRNLTYSQQQAGSNRQTSVSFSSDLFNQQLELYLSYVATIGPPDVLIVGSSRALQGVDPKQLKQSLAANGRSGLTIFNFAVNGATAQVVDFQLRRLLKPQHLPQMIVWADGVRAFNSGRVDRTFNSIIASEGNQLLAAGIRPKLPEDELNIIPQCYKFPQPCRGSFQKASILPVTNTAVGGQDAHPTSKFKSCGTGILPVANIRNCGTGILPVANIGVGGQDAHPTGQLKYCGTGILPVANIRNCGTGILPVANINVMAIRPVSELADAIDSNGFMPLSTRYNPNTYYNDRPYVSGTYDRDYENFNLGGKQAQAFNSVIAFVKSRKIPLVFINLPLTDDYLDGTRRYAEQQFRQQMQQLSRQKGFAFRDLSQRWQNRNEYFFDPSHLNQFGAIAVSRLIAADTSITWPRPKSRTIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXN1</accession>
    <name>A0A2G4EXN1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">gcvH</name>
        <name evidence="6" type="ORF">CP500_016935</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000110">
        <property type="protein sequence ID" value="PHX54293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54293">
        <property type="protein sequence ID" value="PHX54293"/>
        <property type="gene ID" value="CP500_016935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="24"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="14227" checksum="ACCC779597F3675F" modified="2018-01-31" version="1">MALKYPDDLKYLDTHEYIRLEGEIATIGISAFAVDQLGDIVFLELPEVGATLEKGATFGTVESVKAVEDLKAPVTGTVIERNDAIVESPENLAEDPYAEGWLLKVRVDNPREVDDALSVEDYRLMVEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXN6</accession>
    <name>A0A2G4EXN6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54210">
        <property type="protein sequence ID" value="PHX54210"/>
        <property type="gene ID" value="CP500_017230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="213" mass="24718" checksum="0C4CCF19C60C4491" modified="2018-01-31" version="1">MFAVVTPEKIHLPPGTLIKFPGSWQDYQALVEQLGDRQIPRIKYRPGEILLMSPLPVHGKQADIIADVVKVLLDYLGRDYEAFTPITMDLPEVRGVEPDYCFYIDNCAAILGKDRIAWGVEPPPDLVIEVDVTSYTNLDDYLPYQVPEVWLFKKNKLIIYCLQNGRYVESLISRYFPNFNVSEIVEECWQMSRDNHTSTVIRELRRKIERENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXP8</accession>
    <name>A0A2G4EXP8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metal ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_016705</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54314">
        <property type="protein sequence ID" value="PHX54314"/>
        <property type="gene ID" value="CP500_016705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="30494" checksum="7C0928E4A6A0D0B3" modified="2018-01-31" version="1">MMDLIQWFVAPLQHEFMVKAILVSALVGLVCSALSCYMTLKGWALMGDAVSHAVMPGVVIAYVLNIPLAVGAFVFGVGSVMAIGFIKAKTRVKEDTVIGLVFTGFFAFGLVLISKVRSSIDLTHILFGNVLGISDADITQTVIISVITLVTLAILRKDLILFCFDSTHARSIGLNITFLYYVLLSLLSLTAVAGLQTVGIILVVAMLVTPGATAYLLSDNFDHMTLIAIATGVFSSVMGTYISYYIDASTGGCIVVLQTLMFVLAMIFAPKHGLLVRARISGAIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXW7</accession>
    <name>A0A2G4EXW7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 16">Aconitate hydratase B</fullName>
            <ecNumber evidence="5 16">4.2.1.3</ecNumber>
            <ecNumber evidence="6 16">4.2.1.99</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">2-methylisocitrate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">acnB</name>
        <name evidence="22" type="ORF">CP500_016470</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="22 23" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="EC" id="4.2.1.99"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="17">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="5 16"/>
    <dbReference type="EC" id="4.2.1.99" evidence="6 16"/>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54384">
        <property type="protein sequence ID" value="PHX54384"/>
        <property type="gene ID" value="CP500_016470"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00718"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047456">
        <property type="term" value="F:2-methylisocitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01576">
        <property type="entry name" value="AcnB_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004406">
        <property type="entry name" value="Aconitase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015933">
        <property type="entry name" value="Aconitase_B_HEAT-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036288">
        <property type="entry name" value="Aconitase_B_HEAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015929">
        <property type="entry name" value="Aconitase_B_swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06434">
        <property type="entry name" value="Aconitase_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11791">
        <property type="entry name" value="Aconitase_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036687">
        <property type="entry name" value="AcnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74778">
        <property type="entry name" value="SSF74778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00117">
        <property type="entry name" value="acnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12 17" id="KW-0408">Iron</keyword>
    <keyword evidence="13 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9 16" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Aconitase_B_N" evidence="21">
        <location>
            <begin position="5"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_2_N" evidence="20">
        <location>
            <begin position="170"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase" evidence="19">
        <location>
            <begin position="454"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="18">
        <location>
            <begin position="236"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="18">
        <location>
            <begin position="405"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="701"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="759"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="762"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="781"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="786"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR036687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR036687-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR036687-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF06434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF11791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="PHX54384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="871" mass="94300" checksum="470627EF82F5323B" modified="2018-01-31" version="1">MLESYRQHAASRAALGIPPLPLDAQQTSELCELLKNPPAGEEETLVELLRDRVPPGVDQAAYVKAGFLTSIAKGEIHSPLITPTWAVYLLGTMMGGYNVHSLIDLLNPTAESAIPATAARALSKTLLVFDAFHDVLDLSDINPYAKQVIDSWVNAEWFTSRPQLAEAITVTVFKVPGETNTDDLSPAPQATTRPDIPLHALAMLESKMPGALQTIAELKQKGHPVAYVGDVVGTGSSRKSAINSVLWHIGNDIPFVPNKRSGGYILGSAIAPIFFNTAEDSGALPIECDVAKMETGMVITIHPYKGEITNSEGEIISTFTLKPDTILDEVRAGGRIPLLIGRTLTDKTRAALGLETSTIFTRPTIPVDTHKGFTLAQKMVGKACGLSGVRPGTSCEPVMTTVGSQDTTGPMTRDELKELACLGFSADLVIQSFCHTAAYPKPVDVKTHHELPDFMAQRGGVALRPGDGIIHSWLNRMLLPDTVGTGGDSHTRFPLGISFPAGSGLVAFAAALGVMPLDMPESILVRFKGELQPGVTLRDVVNAIPYVAIQKGLLTVEKQNKKNVFSGRIMEIEGLPDLKVEQAFELTDATAERSCAGCTIKLSVETVSEYIRSNVALLKNMMARGYADARTMMRRVAKMEEWLANPVLLEADADAEYVEIIEIDLNEIKEPIVAAPNDPDNVKLLSEVAGDRVDEVFVGSCMTNIGHYRATAKVLEGSGEVKTRLWICPPTRMDEQQLKEEGYYSIFGAAGARTEMPGCSLCMGNQARVKDATTVFSTSTRNFNNRMGKDAQVYLGSAELAAVCSLLGKIPTVQEYMEIVAKKINPFADDLYRYLNFDQIAGFEDEGRVIALEDMPRIEDILGIPEGVLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXX6</accession>
    <name>A0A2G4EXX6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative gluconeogenesis factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for morphogenesis under gluconeogenic growth conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gluconeogenesis factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54383">
        <property type="protein sequence ID" value="PHX54383"/>
        <property type="gene ID" value="CP500_016480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00973">
        <property type="entry name" value="Gluconeogen_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010119">
        <property type="entry name" value="Gluconeogen_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30135">
        <property type="entry name" value="PTHR30135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="SSF142338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01826">
        <property type="entry name" value="CofD_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="52"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="466" mass="50867" checksum="4694C8E4954992DC" modified="2018-01-31" version="1">MSISSFPKALRVWAKARQVVAKSRNPYPFSLRNGRVHQWFKWLSPGLLVKRWLLISASGVVLTSLGLAIWTGMTPIFFFLQLLRNFLTWIAEVVPNYISGPVVIAAGILLILWGQTRSLNSITQVLMPEGNEELVDRLINHRRLHRGPKIVAIGGGTGLSNLLRGLKDDSAKITAIVTVADDGGSSGRLRREIGVPPPGDIRNCLAALADEEKLLTELFQYRFRAGDGLVGHSFGNLFLTAMSDIAGDFEQAIAASSKVLAVRGEVLPATLSDVSLWAELADGRRIEGESSITKANGKILKIGCTPPHPPALPRAVEALREADFIIIGPGSLYTSVIPNLLVPEIADAIARSEVPRIYVCNIMTQPGETDGYTVADHIRAIDRACGRPLFDAVVVQGKVPSAKALIGYSQDNSYPVILDREAVTQLGRRVVIANVMDEDEHTGLIRHNSQRLAGMLLRWYSRAQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY63</accession>
    <name>A0A2G4EY63_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000124">
        <property type="protein sequence ID" value="PHX54107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54107">
        <property type="protein sequence ID" value="PHX54107"/>
        <property type="gene ID" value="CP500_017865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="2">
        <location>
            <begin position="74"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="2">
        <location>
            <begin position="245"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="335" mass="38261" checksum="9DBBE2EE7F003F92" modified="2018-01-31" version="1">MTAQGTTTVEKSLQKVLEKLESARKMQGDWMKNGINFVDLYVDNAGSDWLEEWGKAEEDLEVDKNRSVSVESVKVAIDFPDFQNTQLLEIALNHRSHTDDFSDRLSESPTWQDIKYQRQALLGATIFGAVLTDYLYRKYPNLDRNAISALKSRLADHKQISEFALDLNLNQLKSCGKNGKKMDKKEDNKFLSETFYAVFGAIYLECDRDFDRAGTWLIERFIDQAVSDNICLIELPKNSPKGAAKRRAILGGDVLEAIAIDYLYNSFPERSATQLTHWKNILVTKDIFPKEFKAKLGSQYLELGSNFSRTRDWLVDNFIKTAVDELVEETGNQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY77</accession>
    <name>A0A2G4EY77_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Capsular biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_015835</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000097">
        <property type="protein sequence ID" value="PHX54484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54484">
        <property type="protein sequence ID" value="PHX54484"/>
        <property type="gene ID" value="CP500_015835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_31" evidence="8">
        <location>
            <begin position="575"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="340"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="779" mass="86418" checksum="B0C6BA4E0DC58405" modified="2018-01-31" version="1">MSTGYNFQSTVSKRNGVQPQAVHGISLGNTESSDEQQPLDLGWLFAVVQRRMGIMVAIALLLGGLSGSLVLWKTKKITKFYQGRFQVLVEPITAEGRLSQLLIQSQSANFSADEVNKVGSSVEDSSMVDYPTLLRVLKSPKLLMPLLEKLQVNYGDITYGQVNSQLKINRITYAKDGKEAGTKIIEFTYQDKDPAKIQYVLDTVSKYYLEYSRQERLKQTTRGMAYIDSQLPALRMRVDLLQRQLQLLRQQANLSFPDQTSKSFTDQAGGIGSQQITIEAQLAETRKFYKNLQQQLSQGNISGVVALNPGMYQTLIGQLQTLETQLAVSSTQYLEGSPPMQSLREKRQNMRRLLEKEAESTIKTVAGQIQQLESRQRSLRTSENNLNKTIRNLPSVMRQYGDLERELEVATESLKVFLSKRETLKLGVGQQDTPWTIINEPSIMYDEQGNPLSVTPTNKGKNLAIVLVLSILFAVAVGFLVEVLDKVFHTPEEVKWGTKLPILGVVPRSQKLKKITRKSNHRAPGVKNVADDRSKNPQLQAGFSKFRTDLDYYFLEAFGSLYTNLRLLSPGMSMRSLAITSAVKGDGKSTIAFYLAKTAASVGLRVLLVDADLRSPQLHLQLGLPNVRGLSDVVATDLSLNDAIQRSPEADNLFVLTAGHNPYDPIKLLSSKKMLYLMEQFQTFFDLVIYDTPPLVGLADAHILAAQTDGTLLVVKIDRTDRSLVAKALEGLKISGASVLGTVVNGIKGSKQASSPRSMGFETVYNNQLTVLGNKTPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYA3</accession>
    <name>A0A2G4EYA3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF488 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54458">
        <property type="protein sequence ID" value="PHX54458"/>
        <property type="gene ID" value="CP500_016000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007438">
        <property type="entry name" value="DUF488"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04343">
        <property type="entry name" value="DUF488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="150" mass="17474" checksum="2A03E392E33C98A9" modified="2018-01-31" version="1">MSQKKAINLFTIGFTQKSAEEFFGTLIQAGVRRVIDTRLNNVSQLAGFAKRKDLEYFLRTIGNIEYVHVLDLAPTQDILDDYKKKKGDWDVYEQQFLGLMRDRKIEHKVSSDLIDCSCLLCSEPKPHNCHRRLVAEYLSDKWKNVKINHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYA7</accession>
    <name>A0A2G4EYA7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="5">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="5">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">panB</name>
        <name evidence="9" type="ORF">CP500_015725</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PanB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54514">
        <property type="protein sequence ID" value="PHX54514"/>
        <property type="gene ID" value="CP500_015725"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Alpha-ketoisovalerate binding" evidence="5 7">
        <location>
            <begin position="44"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7 8">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="259" mass="27783" checksum="06888482D19B7F64" modified="2018-01-31" version="1">MSVTTHQLIQWKQQGRSIVALTGYDYAIAQLIDQAGVDLILVGDSLAMPILGYETTLPLTLDEMLHHAKAVRRGVKQALIVVDLPFLTYQESVQQAMHSAGRVLKETGAQAVKLEGGYPAMAATISQLTSAGIPVMGHVGLTPQSVHQLGYKKQGKTVEAGERILQEAIALQEAGAFAVVLEHIPADLADRITQKLTIPTIGIGAGPHCDGQVLVTSDLLGLSEKQPPFAKAYANLRSTITQAVKDYSLEVREGKFPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYD9</accession>
    <name>A0A2G4EYD9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4342 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54539">
        <property type="protein sequence ID" value="PHX54539"/>
        <property type="gene ID" value="CP500_015575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025642">
        <property type="entry name" value="DUF4342"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14242">
        <property type="entry name" value="DUF4342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4342" evidence="2">
        <location>
            <begin position="41"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="123" mass="13012" checksum="14B4A82FCC0D8737" modified="2018-01-31" version="1">MNSQLEQKVTILQDETAAVADATNTTVGTPLFTSEFATEEKVRVEEFKISGDSLIARIKELVQQGKLRRLVIKNSQGRTLADIPLMAGLVGGVAGAIVFPIAAILATVGGFAASLTVAVERKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYF8</accession>
    <name>A0A2G4EYF8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54564">
        <property type="protein sequence ID" value="PHX54564"/>
        <property type="gene ID" value="CP500_015360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="11182" checksum="F50D5199B752AFEC" modified="2018-01-31" version="1">MSDSIARRLEQYTVRRPQEVLIVRVETEGEFDEIAIFKGFSSSLVRSTAFDPEIPVLPEGAKIISIDRLAGPYNPNSPRYLQQGLSWETMKSLLLEIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYL2</accession>
    <name>A0A2G4EYL2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_015515</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54560">
        <property type="protein sequence ID" value="PHX54560"/>
        <property type="gene ID" value="CP500_015515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="7"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="13151" checksum="4AF7636AB79EBD1A" modified="2018-01-31" version="1">MTLTVSLRGTREVRNNYQLFRLTGLLDAFSEATFRKVVTTYIDEGPKHVILDLSTIDFVDSSGLGALVQLVKQAQSWEGTLQVVSNPRVTQTVKLVRLEKFLSLQPSVDEAVKNVKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYX5</accession>
    <name>A0A2G4EYX5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YCII domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000082">
        <property type="protein sequence ID" value="PHX54712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54712">
        <property type="protein sequence ID" value="PHX54712"/>
        <property type="gene ID" value="CP500_014610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10245" checksum="7BA64617A25C5F60" modified="2018-01-31" version="1">MTKYVMWGSYCEDVLEKRAPFRDAHLAGLAKQKESGVLIAIGPTKDLTKVFAIYEAENEATVRELVEADPYWVNGVWTEYEVKEWIQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ25</accession>
    <name>A0A2G4EZ25_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_014490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54746">
        <property type="protein sequence ID" value="PHX54746"/>
        <property type="gene ID" value="CP500_014490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="23"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="156"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="236" mass="26420" checksum="95C705FFC86D8572" modified="2018-01-31" version="1">MEDRFNTRDPQSNINQLIVSTPFFLGLPDPVIERATLHIVTRSHPSNQVILLENDWGTSVYFILDGWVKISTYNLHGKEVTLNILGKGELFGEMAAIEETPRSTDVITLAPTLIGNMPSQDFVQLIHTEPLAGIRLAQLMARRLRQVNRRLRLRESDSTSRVADILLFLAEGQGKIMATGGTEIPNLPHKELSSLSGLARETVTRVLSKLEKKGSIQRDRDVLCIPDLHALERLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ71</accession>
    <name>A0A2G4EZ71_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54809">
        <property type="protein sequence ID" value="PHX54809"/>
        <property type="gene ID" value="CP500_014175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="140"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="447" mass="51379" checksum="F3BEAD6D3439D2D1" modified="2018-01-31" version="1">MTITEILQFVDRVVEKETGEHLDDLEKAVVKGLWQDKTYSEIADECGYKSKNYIGDVSRKLFKILSEHLKEDISRHNFSWTIERVINSQFVGLVNSKINWCPNSPQADANQSIKEKPSKNKGYHDLSLAPKITSFYDRATEVQTLTRWLIDQNVHLVSVLGLSGIGKTTLVKQFVDLNLQKFDVVIWKNLKISQSLDDIINEIITGVDRDSLQTDNKLTQFFNLLRQQRCLIVLDDFQELFSKGELAGEFKTESKNFQNLLTMMTNLEHQSSLILISQEQCQEMISLDEDLYPIQCLELQGLDNTEIVKKWGFKDDEAWTELSDLYGGNPVYLKDIASLIKSIFGGKVADFLKEDSLVVTKDMKSRLTELFKRLSSTEQEIILQLSKFDVPVSREDLRQSLSLSSMDLMNGLRSLGQRYLLQRIEGEKVLFDLSLVVREYVRTCCQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZF8</accession>
    <name>A0A2G4EZF8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54901">
        <property type="protein sequence ID" value="PHX54901"/>
        <property type="gene ID" value="CP500_013655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014056">
        <property type="entry name" value="Addiction_killer_pred"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41791">
        <property type="entry name" value="PTHR41791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028744">
        <property type="entry name" value="Addict_mod_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02683">
        <property type="entry name" value="upstrm_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="12992" checksum="7C12DCFD57CBFB86" modified="2018-01-31" version="1">MEVQPREIQQYKIPDGKIPFSEWLESLRDFKGKAKIVKRLERVSEGNLGDARSLGEGVWEFKIDFGPGYRVYFGQVETTIVLLLCGGDKSTQEQDISKAKKYWTEYRSRKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZN7</accession>
    <name>A0A2G4EZN7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PepSY domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54973">
        <property type="protein sequence ID" value="PHX54973"/>
        <property type="gene ID" value="CP500_013200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="21680" checksum="D85FD5AE5CAFBC23" modified="2018-01-31" version="1">MASINFRKLHRQVAPIIFIPLLLSALTGVAYRLGEDWFGIEGDAAEIFMVIHQGSYLGKELRPFYVLLLALGVIGLIVTGLTMTKFFGGARPERPGAKLDFRKVHRIAAPIILLPLTVSTVTGVIYRVGRSWFKMPKEVGEVFLNIHQGEYLGDFLMPIYVFLVGLGVIFLLVTGINMTGIFRKRRPQTTEEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZQ8</accession>
    <name>A0A2G4EZQ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1517 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54677">
        <property type="protein sequence ID" value="PHX54677"/>
        <property type="gene ID" value="CP500_014740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010903">
        <property type="entry name" value="DUF1517"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07466">
        <property type="entry name" value="DUF1517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="22344" checksum="63908600971F7E74" modified="2018-01-31" version="1">MNALGDRFNQFRGKTRFAVCRVFVHLTGEEVAPVLGILNSTARDAIDADGDLTVLGEGLVEVCNHLLQYDNYWQSAANEGDVFWDEGEAGDYVDELFTDSAQRYLSEPQYNDSVDDKNSPLSLPVTRNVVVILTVAYEGEVPQLETDLADMSALKAGLKALINLNYQQRLRAIQVHFSPAQFGDELTDDQLLVNFSELIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F015</accession>
    <name>A0A2G4F015_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55104">
        <property type="protein sequence ID" value="PHX55104"/>
        <property type="gene ID" value="CP500_012580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021297">
        <property type="entry name" value="YlqD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11068">
        <property type="entry name" value="YlqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="146" mass="16863" checksum="CB6196F35AA9ACE6" modified="2018-01-31" version="1">MEPQLQLKRSINVKVVVTPRWKEEAQQQLQEQINQTDSQLQQLEMQGQRMIAEIQKQNLQPPGPQVMQQIENIQMQVNQKKSELLEQKNQSLQQLQQVQVLDLEQEVNQGQIDGTFTVGLGDNLIQKMQVEVLLRDGIVEVIRGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F087</accession>
    <name>A0A2G4F087_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Isochorismatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55163">
        <property type="protein sequence ID" value="PHX55163"/>
        <property type="gene ID" value="CP500_012330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="342" mass="37659" checksum="A1F3BF59B07BF3CF" modified="2018-01-31" version="1">MTAQTKLPIPDYFDAKKVSEVWRVPYQQRATEATNWAKQHSIKPASSDKNRICLLIIDAQNTFCLPEFELFVGGRSGSGAVDDNLRLCEFIYRNLHLITAIAPTMDTHTAMQIFHPIFWINEAGEHPQPAATSITLEDVQKGIWKVNPAVADSISGGNFSALEKHALHYVKKLSDNGKYPLTIWPYHSMLGGIGHALVAAVEEAIFFHSIARNRQALFEIKGGNPMTENYSVLQPEVLDGCDGNPIAEKNAKFIDKLLEFDAVIIAGQAKSHCVAWTIDDLLTEILVRDSQLAKKVYLLEDCTSPVVVPGVVDFTAAADAAFQRFAAAGMNVVKSTELILGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F095</accession>
    <name>A0A2G4F095_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="8">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">potA</name>
        <name evidence="10" type="ORF">CP500_012060</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55189">
        <property type="protein sequence ID" value="PHX55189"/>
        <property type="gene ID" value="CP500_012060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015594">
        <property type="term" value="F:ABC-type putrescine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03300">
        <property type="entry name" value="ABC_PotA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017879">
        <property type="entry name" value="PotA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005893">
        <property type="entry name" value="Sp_pt_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01187">
        <property type="entry name" value="potA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="19"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="51"/>
            <end position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="376" mass="41904" checksum="C2D923AEBF108874" modified="2018-01-31" version="1">MFQTALNQGTTATDTALDVELRKVFKVFNGETAVRGVDLEIHQGEFFSILGPSGCGKTTTLRLIAGFETPSAGELMIRGQSMTNTPAYRRPVNTVFQSYALFGHMNVWDNIAFGLRIKKLGKTEIEERVREVLQLVKMESFATRFPGQMSGGQQQRVALARALVNRPAVLLLDEPLGALDLKLRKQMQLELSNLHQELGLTFVMVTHDQEEAMSLSDRIAVMNEGRIEQIGSPEEIYECPQTAFVADFIGDTNLFAGKVEAIDRSTVTVRTPAGLKIVVQQSDMWSGVTDDSVVVSVRPEKVYLNLYQPEVSVNCFEGRLKNIMYMGTHVHYVVELTTGDKMTVRQPNTDGSFPDPHTPIYAYWGTTDCLVLSDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F097</accession>
    <name>A0A2G4F097_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55180">
        <property type="protein sequence ID" value="PHX55180"/>
        <property type="gene ID" value="CP500_012415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007378">
        <property type="entry name" value="Tic22-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926">
        <property type="entry name" value="PTHR33926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04278">
        <property type="entry name" value="Tic22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="245"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="284" mass="30793" checksum="42D0714F39F9B296" modified="2018-01-31" version="1">MKSLVRLGAILGIVGSTLLGPSPIGNMSALALPEPQILEKLEFVPVFTIADAQGLPLVTSGTKQGQTTPISVGLIFISQRDAQSFINKELKANNPQLASTARVIPLSLGKIYQLSQANKDKPNELQFDYIPAPQQVESAKTLLKQAGQQVPEFNGVPLFYAKVGTDNGVLTFQQGQKEVIPFFFNKEELQAEVERFKQQQPTVTLPIKIEVVNLEGVLEALRTKNDPFLTQMMLVPSRESLDFVRSLQPAGAGNQNKPPAASPTQPAPRSPAVAPTPSQPRPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0G2</accession>
    <name>A0A2G4F0G2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_011730</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55245">
        <property type="protein sequence ID" value="PHX55245"/>
        <property type="gene ID" value="CP500_011730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="139"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="460"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="592"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="668"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="5">
        <location>
            <begin position="754"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="450"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="928" mass="105006" checksum="C128045CA1A048A6" modified="2018-01-31" version="1">MKSLFKKLLVPHHLEYLALDKDFLIQETSPNVQRFVYSDEIVAGNDVRIPFPELVGTEEILIDIFEGRLPNFDLKAMTRVLDNNLRLYFDMYIVELKDDENNQRLIIFFEDVTDRMGLEQTLVQATNEMNILLSTLASTNKYVEKIITSMAEVLLVTTGTGKIKKVNQAAETLFGYSESELVGREINAIAAVGESLHTLSQESQLSPTKGEVICTAKTGEKLTVAFSCTAIPTEINSISDTRIDTQDFLYIGRDVTDKKRASKRKVAQYVTTRILSASETTKKAIAAILPVICDSLGWDTAELWMPEIGEKLLSGTKSKREIPISDPTLLRCVASWTKRSISIPKFRECAKQITFAEGEGLPGRVWASGSPEWMADVVENEFFIRREIAAEEGLHGAFGFPILGDYEQEMSTKSVLGVMTFFSLEVQSFDEELIQTMATIGSQIGQFIKRKQAESALRESEEKLRDLFENASDLIQTIGSDGHFLYVNRAWEQTLGYSEEEMASLTVFDIIHPNSSHNSIDVLYQAIHKKNINENTFYPNFIQAIFITKYHQQIWLEGSISCKFAEGKLVAIRMILRDITARKEAEDALAKSVSLLQATFDSTADGILVIDRTGKIVTFNREFVEMWGIPNEVMALRDDATMMAFMLEQLKDPEAFQERIESLYEHPEAESYDLLEFKDGRFFERYSEPQRLEDEIIGRVWSYHDITERKQAEDALREEQEKSEKLLLNILPKAIAERLKRNETTIAEYFPEVTVLFADLVGFTSFSTTMSPIELVELLNQIFSGFDLICERLGLEKIKTIGDAYMAVGGLPEPRADHAEAIAQMALDLQTEIARFNAKNNQSFSIRIGIHSGPVVAGVIGIKKFIYDLWGDTVNIASRMESHGLPWRIQVSETTYKLLEHKYLFDERGTIEVKGKGAMTTYLLIGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0G6</accession>
    <name>A0A2G4F0G6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">livG</name>
        <name evidence="5" type="ORF">CP500_011760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55250">
        <property type="protein sequence ID" value="PHX55250"/>
        <property type="gene ID" value="CP500_011760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="15"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="270" mass="29549" checksum="5EEE66ACD4FB06F9" modified="2018-01-31" version="1">MISEPLTLSKTNPVLAAKGLTRRFGGLIAVNDVSFTVEKDEIFGLIGPNGAGKTTLFNVMTGLIPASSGNLIYQNENISQLKPYQIANKGIARTFQNIRLFGELSVSENVAIARHIHSRSHNPVLSLLAGIFALPAANAMERETHEKALELLDLVGLGDRADEQAKNLSYGDQRRLEIARALALEPQILLLDEPAAGMNPNEKHKLSDFIREVRQKFNLTVILIEHHVPLVMGLCDRIAVLHFGQLIALGEPAIVRNDPAVIEAYLGDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0J2</accession>
    <name>A0A2G4F0J2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-nucleotidase SurE</fullName>
            <ecNumber evidence="5">3.1.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">surE</name>
        <name evidence="7" type="ORF">CP500_011800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55258">
        <property type="protein sequence ID" value="PHX55258"/>
        <property type="gene ID" value="CP500_011800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00060">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SurE" evidence="6">
        <location>
            <begin position="4"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="29204" checksum="593D147F8AAD2CF8" modified="2018-01-31" version="1">MKLLISNDDGIFAQGIHSLANALAAAGHDVSVVCPDRERSATGHGLTLHQPIRAEIVESIFDPAVKAWACSGTPADCVKLALWALVDKPPDFVLSGINHGPNLGTDILCSGTVSAAMEGFMEGIPSIAFSLASYTSQEFDPAVNFAVTLLAQLEKQPMAKPMLLNVNIPAVKQAEITGVAIARQGIRRYFDIFQKRTDPRGKTYYWLAGELLEDVEETPDPAVPHDIPTDVQAIRDHKITVTPLQYNLTCGADLHSLRDWQFKDFRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0L4</accession>
    <name>A0A2G4F0L4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54997">
        <property type="protein sequence ID" value="PHX54997"/>
        <property type="gene ID" value="CP500_013105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="31"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="64"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="157" mass="16631" checksum="83EC9B66DFB1EF0F" modified="2018-01-31" version="1">MTDLMNVAKTGDVSTLEGAEQYADINAKDEEGSTALTVAAEAGHFDIAKKLLADGADVNSQDNDGWTALMSAAAAGHREIVQLLLEAGSEVNAKTNFGLTALMSAAGSGRTEVVELLIEKGADIKAKDHNTWTALIWASSEGHQDAVEVLKRSRDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0M3</accession>
    <name>A0A2G4F0M3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55312">
        <property type="protein sequence ID" value="PHX55312"/>
        <property type="gene ID" value="CP500_011445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="192" mass="21463" checksum="6D8FF6ECD09787A3" modified="2018-01-31" version="1">MMKRISENNSQNSQNQVQKQPSPLVLALVLTGILVLEMYPALMHTAAAHAGALKNSLTNLESQEHPRVKQFLAAPVLEKISYSEFALNNLTSEPDNLNQGSRQNALNQLPASIIEAVRLDLSRQTGIAARRLRVTESSRQSWPNTCLGLAKSDELCGQMIVEGWRVVVSDGRQFWVYRTDARGKILRLEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0R8</accession>
    <name>A0A2G4F0R8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CRISPR-associated exonuclease Cas4</fullName>
            <ecNumber evidence="6">3.1.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cas4</name>
        <name evidence="8" type="ORF">CP500_011210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+) or Mn(2+) required for ssDNA cleavage activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CRISPR-associated exonuclease Cas4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.12.1" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55359">
        <property type="protein sequence ID" value="PHX55359"/>
        <property type="gene ID" value="CP500_011210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013343">
        <property type="entry name" value="CRISPR-assoc_prot_Cas4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022765">
        <property type="entry name" value="Dna2/Cas4_DUF83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01930">
        <property type="entry name" value="Cas_Cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00372">
        <property type="entry name" value="cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 6" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas_Cas4" evidence="7">
        <location>
            <begin position="10"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="197" mass="22771" checksum="F04F3315C10FEA3B" modified="2018-01-31" version="1">MNDDDYISIASLNQYSYCPHRCWRMSCAGEFTDNQYTIEGTSLHDRVHTMGEINRDETWQVRAIWLKSEKYKLIGKSDLIESTDGEIYPVEYKRGRKGEWDNDELQVCAQALCLEEMTGKNIATGYVYYAQSHQRQLVDISEQLRQEAIMTISAIQILLQTGKMPPANYSKRCQGCSLYQQCLPQAAEKVLRYQEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0T7</accession>
    <name>A0A2G4F0T7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CRISPR-associated endonuclease Cas1</fullName>
            <ecNumber evidence="8">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cas1</name>
        <name evidence="9" type="ORF">CP500_011205</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer, forms a heterotetramer with a Cas2 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CRISPR-associated endonuclease Cas1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55358">
        <property type="protein sequence ID" value="PHX55358"/>
        <property type="gene ID" value="CP500_011205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01470">
        <property type="entry name" value="Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002729">
        <property type="entry name" value="CRISPR-assoc_Cas1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042206">
        <property type="entry name" value="CRISPR-assoc_Cas1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023843">
        <property type="entry name" value="CRISPR-assoc_Cas1_cyanobact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042211">
        <property type="entry name" value="CRISPR-assoc_Cas1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01867">
        <property type="entry name" value="Cas_Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00287">
        <property type="entry name" value="cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04093">
        <property type="entry name" value="cas1_CYANO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="333" mass="37732" checksum="2A2CF13823735E09" modified="2018-01-31" version="1">MGTLYINQDDVFIGKTDERLNVKAKNQTLQDVPLIHLDGVVIVGRATISPAAVAELLQRKIPLTFITDTGHYLGKLEPELSKNIFVRNAQWKAAGETPQAIHVVQGFIRGKLKNYRTSLSQTQREHSELNLGSAIMQISNAIAKIDKTDNINSLRAQEGAGSAAYFRVFNQLIRAEGFVFKPRHRPATDPVNSLMNFAYTLLSHDVQSAINIVGFDPYLGYLHVQRYGRVGLAFDLMEEFRPLVADSVILNAINRRILTPNDFTVEPLSNVVRLSETGRKEFLRLYEKKKQSEFKHPVLKRKCTYQEAFEIQGRLLAKYLMGEIDKYPPLVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0U8</accession>
    <name>A0A2G4F0U8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleotidyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55368">
        <property type="protein sequence ID" value="PHX55368"/>
        <property type="gene ID" value="CP500_011255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041633">
        <property type="entry name" value="Polbeta"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18765">
        <property type="entry name" value="Polbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Polbeta" evidence="2">
        <location>
            <begin position="15"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="151" mass="17640" checksum="AFB3BF82063B0251" modified="2018-01-31" version="1">MLQISPTLTELQEIASQLPEQIPYLKMLILFGSRARGDTHAKSDWDFAALYDEKLREEYCQDRGFSWFEVPGILGQVFGINSDEIDVVELNRCSPLVANFIARDGKLLYEKESGQFERFVKTHLMNDLELQELERELYQSINDFLKDWRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0V2</accession>
    <name>A0A2G4F0V2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55404">
        <property type="protein sequence ID" value="PHX55404"/>
        <property type="gene ID" value="CP500_011055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9347" checksum="B539F5EEE64929D3" modified="2018-01-31" version="1">MISELMVQPSYWIDSEISMQKVRNLYLFKFTENLQARLEELAERKKANLLTSEEVVELASLLELDRIFTLINAKVIAASCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F172</accession>
    <name>A0A2G4F172_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_010365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55502">
        <property type="protein sequence ID" value="PHX55502"/>
        <property type="gene ID" value="CP500_010365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="23"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="59"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="254" mass="27824" checksum="2C2FB5382E4DDEDD" modified="2018-01-31" version="1">MPELQTETKQELNEEVLSKPVIVGLENVTKVYGIGDLEVRALNGVSLTVRQGEYCAIMGASGSGKSTAMNIIGCLDRPTSGSYYLDGVDVAQMPEADLAGIRNLKLGFVFQQFHLLSQLTALENVMLPMVYAGVAAAERRDRAVDALTKVGLESRLQNRPNQLSGGQQQRVAIARAIVNRPVLLLADEPTGALDTKTTQEVMDIFTEFNDSGMTVVMVTHEPEVARQTRRVVWFRDGQVIHNNLKPSELSHAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F188</accession>
    <name>A0A2G4F188_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="9">2.7.7.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose pyrophosphorylase</fullName>
            <shortName evidence="9">ADPGlc PPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glgC</name>
        <name evidence="12" type="ORF">CP500_010440</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9 10">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55516">
        <property type="protein sequence ID" value="PHX55516"/>
        <property type="gene ID" value="CP500_010440"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00624">
        <property type="entry name" value="GlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023049">
        <property type="entry name" value="GlgC_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00808">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00810">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9 10" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="11">
        <location>
            <begin position="6"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha-D-glucose 1-phosphate binding" evidence="9">
        <location>
            <begin position="177"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX55516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="429" mass="48191" checksum="3F4438A91F8E28F2" modified="2018-01-31" version="1">MKRVLAIILGGGVGTRLYPLTKLRAKPAVPLAGKYRLIDIPVSNCINSEILKIYVLTQFNSASLNRHIARTYQFSGFTEGFAEVLAAQQTQENPDWFQGTADAVRQYLWLLEQWDVDEYLILSGDHLYRMDYRKFVDRHRETNADITLSVLPMDEKRASDFGLMKIDDNGRVVSFSEKPKGDALKEMQVDTTKLGLTSEQAKESPYIASMGIYVFKKEVLIKLLKESLDQTDFGKEIIPASAKDHNVQAYLFDDYWEDIGTIEAFYDANLALTKQPQPPFSFYDENAPIYTRPRFLPPTKLLNATVTESIIAEGCILKQCRIDHSVLGVRSRIEAGCTIQDTLVMGSDFYEPDAERHSALENSGVALGIGADTTIRRAIVDKNARIGCNVQIINKDRVEEANRESEGFYIRSGIVVVLKNATIPNGTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1E8</accession>
    <name>A0A2G4F1E8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type II toxin-antitoxin system HicA family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_009955</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HicA mRNA interferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55591">
        <property type="protein sequence ID" value="PHX55591"/>
        <property type="gene ID" value="CP500_009955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038570">
        <property type="entry name" value="HicA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8353" checksum="B56C7FAC10EA54CC" modified="2018-01-31" version="1">MPKKIRELKSLLLKAGFTYRSAKGSHTRWVHSLLPNEGITIAGNDGDDAKLYLEREVNRKIGILKAIEEEESES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1E9</accession>
    <name>A0A2G4F1E9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55604">
        <property type="protein sequence ID" value="PHX55604"/>
        <property type="gene ID" value="CP500_010020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="688" mass="77981" checksum="B8CFAC11B2337F70" modified="2018-01-31" version="1">MQVQLSWEDPVTGEQWQPVLTLPVALGRKLDQMPTTLEGQQVARTVLNSKQVSRFHALIAIVNGQLAITDKSVNGIYVKDRWIRQSSEPLASGDTLKIGPYSITFTLLPETESESTEAVSPSSTIFDPESSIAEAQAVRATPNKSPDSGMFFHPESDLLDYRSAITQEKNPPLPNIFGAECVSIEEIKRTVLQSHYEEKDYAAIGGGMGSFAWVDAIRIWGVKAEQIRVIGRGEHQPYSRYRLICRNSQIPEYERIRSGSDSCPDNIWGWPGYAIREAWRNLFSGNLIPAFKYLWQVFAEPVLADTYSPRSGDVFASMDRESDRIGWKAMWRSGNILAIRKTDDGRYVIVYSPTEARVHEYQVLVARYVHLCIGYPTVKFLPDLLEYRETTGDCQSVVNAYENHESVYKQLKKQGGTVIVRGRGIVASRIIQRLNEIRQQNDQITIIHLMRSPNPKGGKFGSAQRYVENHWEFQPYNWPKGTWGGDMRKMLEAANPPGRYQLLEDWAGTTTADRHDWRQIIDQGRKEGWYRITFGKIEKVERNQQGQPVTWISSSSAKSQIKTNIEADFIIDATGLESNPDGSPLLKDLIGHYRLPLNPFGRLHVANDFEIKEMRNQDKRKKNRGRMYAAGIMTLGGPYAPVDTFLGLQYAAQRSAEGLVRAGAPKIKYLNGIGSFWQWIKWATNQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1J0</accession>
    <name>A0A2G4F1J0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannose-1-phosphate guanylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55630">
        <property type="protein sequence ID" value="PHX55630"/>
        <property type="gene ID" value="CP500_009880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="353" mass="38576" checksum="15036560DE26796B" modified="2018-01-31" version="1">MTKTLIPVILAGGKGERFWPLSRKQRPKQFLSLDGSGKSLLQATADRLLTLGGGWDDLWVVTSEMLAAGVREQLPLLPPENLLAEPEGRDTAPAVAWSAIEIAKRYGEDAVVGFFPADHWIGEPEEFEKTLEAAAELARNQDAIATLGVKPSYASTGYGYIEQGEEIGSFGGFPAYLVARFTEKPDRATAEEFVTSGKFSWNGGIFVFRVGTVLTELRNYVPEMMAALEAKGAAAYSQLPKISIDYALMEKTQKACVLPVGFSWDDLGDWNAIARLLQGDKPNVELAKHVGIDTKGGIFYAADENEVIVTIGLEDVVVVRDGNVTLIVKKDRTQEIKQVIKVLGEDEKLKDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1K4</accession>
    <name>A0A2G4F1K4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55643">
        <property type="protein sequence ID" value="PHX55643"/>
        <property type="gene ID" value="CP500_009530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10002" checksum="D68AEB1DACFB6093" modified="2018-01-31" version="1">MENLLLTVVIILQLVLIFLILQREYQLLPEGLGVRGQSQLSNATAQKQSASSKNLWDNPLPASEELKLTVAEFKDNYNRSEPWDGDFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1P4</accession>
    <name>A0A2G4F1P4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpmI</name>
        <name evidence="4" type="synonym">rpl35</name>
        <name evidence="6" type="ORF">CP500_009700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55672">
        <property type="protein sequence ID" value="PHX55672"/>
        <property type="gene ID" value="CP500_009700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_L35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="PTHR33343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7408" checksum="834936D7F68B1900" modified="2018-01-31" version="1">MPKLKTRKAAAKRFRATGTGKIVRRKAYKSHLLSHKSSARKSRLSKLVVIDETNDANVRLMLPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1T7</accession>
    <name>A0A2G4F1T7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55709">
        <property type="protein sequence ID" value="PHX55709"/>
        <property type="gene ID" value="CP500_009450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="73"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="202"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="248" mass="28542" checksum="EE5244385BCEA555" modified="2018-01-31" version="1">MTQGICLEKLPADLEQERLPRHVAVIMDGNGRWARDKGLPRIMGHRRGASVLKELLRCCKDWGIPALTVYAFSTENWGRPEGEVDFLMSLFEGKLREELREMVAEDVQIQFVGNLQALPKSLQAEIERSVSATQHNRGIRLTVATNYGGRQEIVQACRAIATQVQEGKLQPSEIDETLFKRYLYTADVCDPDLLIRTSGEMRLSNFLLWQMAYSEIYITETLWPDFDRSEFHRALSTYQKRSRRFGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1W6</accession>
    <name>A0A2G4F1W6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative toxin-antitoxin system toxin component, PIN family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55751">
        <property type="protein sequence ID" value="PHX55751"/>
        <property type="gene ID" value="CP500_009090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002850">
        <property type="entry name" value="PIN_toxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34610">
        <property type="entry name" value="PTHR34610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00305">
        <property type="entry name" value="TIGR00305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="8"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="15834" checksum="7B23D952F45E5DA0" modified="2018-01-31" version="1">MPQKPTIKVIIDTNLWISFLIGKELANLKQLIVDRTIQVVLCEQIIEEINLVTQRPKLQKYFPATKVQELLELLRIIGLWIEVTSEVSICRDAKDNYLLALAKDSQANFLITGDGDLLTLVNFEGTEISTYKEFLGKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F228</accession>
    <name>A0A2G4F228_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TVP38/TMEM64 family membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55795">
        <property type="protein sequence ID" value="PHX55795"/>
        <property type="gene ID" value="CP500_008890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="PTHR12677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="242" mass="26076" checksum="F47487135CD101D2" modified="2018-01-31" version="1">MNDSRSQIDENPPPSNKWKLIFLLVLVVALIVAAKFFNFQGILKNALESIAHLGPWGPAAFILIYIVATVLFIPGSLLTLGSGVLFGVIGGAICVSIGSILGATCAFLVGRYLTRDWVSQQIQGNAKFQAIDAAVASEGWKIVLLTRLSPIFPFNLLNYAFGVTQVSLRDYFFASWIGMIPGTVMYVYIGSLAGSLAALGSQGRSRTTAEWTLYGIGLVSTIALTVYVTRFAKKALEEKISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F279</accession>
    <name>A0A2G4F279_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HSDR_N_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55845">
        <property type="protein sequence ID" value="PHX55845"/>
        <property type="gene ID" value="CP500_008715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029464">
        <property type="entry name" value="HSDR_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13588">
        <property type="entry name" value="HSDR_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSDR_N_2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17164" checksum="03F4D97271EA8BAC" modified="2018-01-31" version="1">MKTSQPDIIVTSQDGEYLMLVEVKLKDISIGAQNAIEQLKHTMASIGCSVGLVVAGERVILLRDSLEKYNGESIYVVGEAQLPDSLLPLADEQWKGLPEIEFEARVQRWLEKLKLTASMESFPSDLKNLLGEPIISLLRMGEVRAGGPRWSKVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Q1</accession>
    <name>A0A2G4F2Q1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CP500_007420</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56053">
        <property type="protein sequence ID" value="PHX56053"/>
        <property type="gene ID" value="CP500_007420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="9" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M1_N" evidence="16">
        <location>
            <begin position="23"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="15">
        <location>
            <begin position="241"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="835"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX56053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="873" mass="98735" checksum="1D1AC268799B4BD3" modified="2018-01-31" version="1">MSHTYFDSENGHKSFEMPGARPHYNPDRPGQVEHIFLDLVLNIPKQSFRGTCSIRINPVRSGIDKLTLDAVNLKIKSVKVGDTKQNFDSDGEFLQIQLHEATEAYKPITIAIDYSVEKPQRGLYFVGPDKHYPDKPTQVWTQGEDEDSRFWFPCFDYPGQLATSEVRVQVPKQLFAISNGELIKTETDGDDKIYHWSQTQVHPTYLMTLAVGDFAEIEDEWNGKPVNYYVEKSREADAKRSMGKTPQMIEFFSQAFGYPYPFPKYAQVCVDDFIFGGMENTSTTLLTDRCLLDERATLDNRGTESLVAHELAHQWFGDLVVIKHWSHAWIKEGMASYCEVLWTDKEYGREDAAYYMLNEARSYLAEDSSRYRRPMVTHVYREAIELYDRHLYEKGACVYHMIRAELGDELFYKAIQTFVQDNAHKTVETIDLLRAIEKATGRNLMFLFDQYVYRGGHPDYKVAYAWDGDSKLAKVTVTQTQVKDGKNGNTKDVFDLKIPIGFGYKPEKDDSDDSTSSAPQLKTFTVRVYEREQSFYFPLEEKPAFVSFDVGNKYLKTVSLEYPIAELKAQLLFDPDPVSQIYAAQALAKKGGLEAVNTLSEVLKKERFWAVRAEVASELVEIKLDQAFDGLVAGLKDKDARVRRAVVGALGKIKTHETYKALRSIVEKGDASYYVEAAAASAIGGIAAANPDEKPTDEQVLKELKLVLKERQGWNEVVRSGAIAGLAQMKTSEDALNLILKYTAAGTPQALRLGAIRALGTISTGQTNINLERILQRLAEFSRETFFLTQVSVVAALGQMETRKAIQILRSLADQTPDGRVRRMADEAVQRVQKNAGSDAAVKQLREELDQVKKDNQDLKSRLESLEAKSKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2R6</accession>
    <name>A0A2G4F2R6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3067 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56046">
        <property type="protein sequence ID" value="PHX56046"/>
        <property type="gene ID" value="CP500_007385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021420">
        <property type="entry name" value="DUF3067"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35126">
        <property type="entry name" value="PTHR35126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11267">
        <property type="entry name" value="DUF3067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="12336" checksum="9E3B6DFA78EADCF4" modified="2018-01-31" version="1">MTGKDLHQLLLEKWGKSYDIRLRRTRGKIFVQVMWKYLEQVSFPMTEADYFEHLDAVANYLNGWGSAAQVREYIVTTRDRPRLGKAVSIPLDLGERASEWLLDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2S5</accession>
    <name>A0A2G4F2S5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56052">
        <property type="protein sequence ID" value="PHX56052"/>
        <property type="gene ID" value="CP500_007415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15751" checksum="E6C4C7A310066317" modified="2018-01-31" version="1">MNTRSIVLVKQSGVIPYRVINGQIEVMLITSSSGKRWVIPKGLIEHDMTPEDSAAKEAWEEAGLLGQVFPDSMGTYEYYKSGYICQVDVFLLQVKTVLENWPEAHKRKRQWVSIPKAIKRVCEPELKLIFGDLSHRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2U7</accession>
    <name>A0A2G4F2U7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56068">
        <property type="protein sequence ID" value="PHX56068"/>
        <property type="gene ID" value="CP500_007500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="199" mass="22381" checksum="3D8227F06DF6C8C1" modified="2018-01-31" version="1">MALEVSVNAFVLHPLHLSSFLPGLPLDSLFSTQGIMVMLLAAYAGAMWMFLTSAPKVYTVMVSDLEQARQFYEGMLNLPVAEVPLHYYYNYEQTLGTTGIDPLYLSPNVGRGTSSQAMGTSEGLWYQLMKNTQLHIISGAGAGEKNRQRHVCFDRDCLDQLLMRVQTCGIKYKIRREKPLNFLVKDYDGRVIEMAEVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2W3</accession>
    <name>A0A2G4F2W3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56092">
        <property type="protein sequence ID" value="PHX56092"/>
        <property type="gene ID" value="CP500_007240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039564">
        <property type="entry name" value="Peptidase_C39-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13529">
        <property type="entry name" value="Peptidase_C39_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_C39_2" evidence="1">
        <location>
            <begin position="178"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="342" mass="38368" checksum="3A964333E9484C56" modified="2018-01-31" version="1">MKLQNFLKSKIRYDAKAIAADDELSRQVQTRLIDLGLLKPPVDGIFGPLSTAALHRFQTLMKCGELGFLGAITAEKLIETKKGDIPTPPIVLKILKDTVFKAKPLATSQLLDAEKQSIPAGKEFELIAFAPIRGHLRIALRNQSFKGSGIWYVLGTQAQVTQEGVVLYPKVNPPTVRLGVPYRSQLDNFYNPTGSCNVTSIAMCLDFLNIPRRKKTGQFEDELYEYAIAKNYSRWEALDLAKIVKDYGAQDYFTESATIQDVKDWLASGNPAVIHGYFTSFGHIIVVAGYDNLGFFVHDPYGEWFPEGYNTSVSGSYLYYSERLIRNVCMPDGNFWVHFISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Y2</accession>
    <name>A0A2G4F2Y2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56109">
        <property type="protein sequence ID" value="PHX56109"/>
        <property type="gene ID" value="CP500_007325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13996" checksum="C586486087975054" modified="2018-01-31" version="1">MQKVTKRKKPSNLLENPLRENLDLLDQIRADAVNDIESLTENFQHMTLVAESVQQNYQALLAQNHLLKSTLLSIIDECECRQGNQCDRCQRILQILAGDNPEQKLDPVLKYKAILTQIRKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Z5</accession>
    <name>A0A2G4F2Z5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NAD(P)H-quinone oxidoreductase subunit F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_007005</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56130">
        <property type="protein sequence ID" value="PHX56130"/>
        <property type="gene ID" value="CP500_007005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010217">
        <property type="entry name" value="NU5C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01960">
        <property type="entry name" value="ndhF3_CO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0874">Quinone</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="589"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="9">
        <location>
            <begin position="73"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="8">
        <location>
            <begin position="140"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="619" mass="67029" checksum="5929FD9A5110C9EB" modified="2018-01-31" version="1">MAQILLQTVWFIPCYPLIGGVLSMLWFPAVTRRTGPRPSGYVNAILTLFAFLHGVIALTAIWNQPAQEQFIPWLNVAGLDLTIPVEISAVTVGATVLITGLNLLAQIYAFGYMEMDWGWARFFSLMGLFEAGMCGLVLCNSLFFSYMILEVLTLGTYLLVGLWFNQSLVVTGARDAFLTKRVGDLFLLMGVVAILPLAGTWNFDELAVWAQTAKIDPTVATLLALALIAGPMGKCAQFPLHLWLDEAMEGPLPATVLRNTVVVETGAWILIKLQPVIALSPIGLKATIIVGAATAVGASLIAIAQIDIKRTLSYIVSSYMGLVFIAVGTGQIQTALTLMFAYTLAMGLLVMSIGSVVWNSITQDVRALGGLWGKRPISAISFIVGSAGLVGLPPFGCFWALSEFTSGLWETHPFLLGIVLFVNGVTAFGLVRVFGLVFGGKPKQMTERSPEVHWPFILPMTILMGFTLHVPHLLAAWQLLPVASWNYTATGLVVLSSAIGIGAGAFVYLNEKWEKPVQIGSQSLQDFFAYDFYTAQLYRVTVIFAVGLVAQIISWVDRNIVDGFVNLIGLTTVFGGQSLKYNVNGQTQFYVLTILFGVGLLGLIVSWPLLARLSLIVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F358</accession>
    <name>A0A2G4F358_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_006700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56192">
        <property type="protein sequence ID" value="PHX56192"/>
        <property type="gene ID" value="CP500_006700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032524">
        <property type="entry name" value="ABC_tran_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16326">
        <property type="entry name" value="ABC_tran_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="320"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="572"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="352"/>
            <end position="359"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="640" mass="71943" checksum="458F6223384C2A59" modified="2018-01-31" version="1">MTIFTLRSIKKDFGIKELLTDASFSLDEGDKVGLIGTNGSGKSTLLKMIAGLESIDSGDRWVNPGATIVYLPQQPDLDENHTVLEQVFADSGEQMALVREYEEISDHLSHGKGDTDKLLARLSAVSERIDEVDAWDLETKAKLILTKLGIEDFDAKIGDLSGGYRKRIALATALLSEPDVLLMDEPTNHLDALSVEWLQNYLNGYRGALLLITHDRYFLDRVTNRILEIDRADLFNYSGNYAYYLEKKALAEESAASTQRKHAGVLRRELEWLKKGPKARSTKQKARIDRIKDMRAEEFKTANGKVEIATAGRRIGKKVVELLNIRKAYGDRTLIKDFTYNFTPEDRIGIIGCNGAGKSTLMDIITGRIQPDSGTVEIGTTIHIGYFDQHSEDLIPNEDQRVIEYLKSVGELVKTADGEIITASQMLEKFLFPPIQQYAPINKLSGGEKRRLFLLQVLMSAPNLLILDEPTNDLDVQTLAVLEDYLEDFNGCVIVVSHDRYFLDRTIDMVFSLEPGGNLRLYPGNYSVYLDHKKAEEAKELKAQKNKGKLPTATEANNPKVEAQAPKPNKLTFNEKREYDQLEAKIPQLEAEKAEIEQILSLNSPSGFSEVKKLSERLGKLNQEIERATEKWMELAERVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F398</accession>
    <name>A0A2G4F398_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56226">
        <property type="protein sequence ID" value="PHX56226"/>
        <property type="gene ID" value="CP500_006585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="164"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="414"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="642" mass="73650" checksum="A62C6342C869FF01" modified="2018-01-31" version="1">MEKLVTLNISGEFDKGFVVQAEVRQDGGITKNQVSLAIAGASGKLPPHPELLEQYRHWRRLYNKTEEFWPSRLTAKKDSVKNHDDQERVKQQAFEACRKAAKLLVEILNSWLQSPDFKPIVDLLSNHLHDSTHTRILLATENHWLRRLPWCEWNLLEHIPNAEVVLASPKFKQVKGSGNSGKKEKVKILVILGDNAGTDADEDVIKQLIPDAEFCWLKEPQRRDLDAPLWEQRWDILFFAGHGKTESDGSIGKIKINSHDWLTIDEIKNHLKRAIKNGLKLAIFNACDGLGIAYQLAEGEDLYLPQMIVMREILPIALAPKFLQYFLEAYTQGLSLYMALRNSRKRLQIEEKDFPCASWLPVLYQNPAELPLNWSELFTNQLIIDPTLVEGIIAAGAKDEFFLFNEPYSCDLPKIVVVGTSVVGKSSLVNELFGGRNVVRVSPVPQDDEQTVEENWAGLFKLIDSVSYDQFPEEVEQNIKGSDVVVHLWDINTIRRDDRQLYKLIINAGKPCITAINKCEQYTPEKRKIIIQNAQNAMSSLFIEISVTAKDNLSQLVLLIIKALPLELKSIAIEKIDKIEKIYRCRKVSKKIILETEEQAAIIPFLMNKRQLSTEPHKYLHELYVTMVEKIEEQYIQRRFYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3G6</accession>
    <name>A0A2G4F3G6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNAse_A_bac domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56324">
        <property type="protein sequence ID" value="PHX56324"/>
        <property type="gene ID" value="CP500_005935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041436">
        <property type="entry name" value="RNAse_A_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18431">
        <property type="entry name" value="RNAse_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNAse_A_bac" evidence="1">
        <location>
            <begin position="65"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="176" mass="19082" checksum="14E5665EF80C1A21" modified="2018-01-31" version="1">MKTQLDRWKKFLGILCAIASIIVLFQSAITPVSAQQIVSIPGQTTVAFAPGIPGGGLDFHEAAGGHTLEKHVGKTEAELAQRLASDQRISAASSFTYRSVAESAIAEAMEEKKSAIDSWVKKGTNRYTIKYDTHKVIGITLRRGASKATSTSRLKIILQRSTKLSPGYFILTAYPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3J9</accession>
    <name>A0A2G4F3J9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA phosphorothioation-associated protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56353">
        <property type="protein sequence ID" value="PHX56353"/>
        <property type="gene ID" value="CP500_005785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023983">
        <property type="entry name" value="DNA_S_mod_dnd_assoc_4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04062">
        <property type="entry name" value="dnd_assoc_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="17785" checksum="4A2171B4EC21DB58" modified="2018-01-31" version="1">MAANRIRIAKDKADLVKSLTSSEHKSSPFQTYADVIAFAASLGNKRKKRLPLGDISKREPGSIDLDIFISRGYDMAIKLIAIAETKNPHILSHLDEKVEAERLQIFEEYANGGLEILREEFRGAADYTDRLLLFLISERDNQHRSNEEFDLSKFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3R1</accession>
    <name>A0A2G4F3R1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin prenyltransferase UbiX</fullName>
            <ecNumber evidence="5">2.5.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ubiX</name>
        <name evidence="7" type="ORF">CP500_005535</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2</text>
            <dbReference type="Rhea" id="RHEA:37743"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:87467"/>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
            <dbReference type="EC" id="2.5.1.129"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UbiX/PAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.129" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56378">
        <property type="protein sequence ID" value="PHX56378"/>
        <property type="gene ID" value="CP500_005535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106141">
        <property type="term" value="F:flavin prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01984">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004507">
        <property type="entry name" value="UbiX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374">
        <property type="entry name" value="PTHR43374"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00421">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0288">FMN</keyword>
    <keyword evidence="1 5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavoprotein" evidence="6">
        <location>
            <begin position="12"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="18"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="110"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="209" mass="23065" checksum="DBD55721405F1290" modified="2018-01-31" version="1">MTNSVSVPAQPLIVGVTGASGLIYAVRTLKYLLEADRAIELVASKSTYMVWQSEQNIRMPAEPTLQEEFWREQAGVPTMGKLRCHPWQDVGANIASGSFRTQGMIIIPCSMSTLGKLAAGLSSDLLERAADVQLKEGRKLVLVPRETPFSLIHLRNLTTLAEAGARIVPAIPAWYHNPQTIEDLVDFVVARTLDQLGIDCVPLKRWKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3U3</accession>
    <name>A0A2G4F3U3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_005490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56454">
        <property type="protein sequence ID" value="PHX56454"/>
        <property type="gene ID" value="CP500_005490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="PTHR12668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="10902" checksum="EBDDD8E998FA5615" modified="2018-01-31" version="1">MNLGIAAALGYGILTLIGGIMGYLKAKSQASLISGLVSGSLLILAGTAELMGQSWGLILAAAISAALAIVFVMRLVKTRKFMPAGMLILASLASLGAIAYEISGQYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3U7</accession>
    <name>A0A2G4F3U7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Photosystem II S4 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56432">
        <property type="protein sequence ID" value="PHX56432"/>
        <property type="gene ID" value="CP500_005350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017506">
        <property type="entry name" value="PSII_S4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040591">
        <property type="entry name" value="YlmH_RBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17774">
        <property type="entry name" value="YlmH_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03069">
        <property type="entry name" value="PS_II_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="1">
        <location>
            <begin position="186"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="261" mass="28978" checksum="46B417B7D78DADB7" modified="2018-01-31" version="1">MANLQREELLKGIENRESVARVIDCAEQAIKTWEVTLTDFMSPPELADAKVVFKRLSDVELVAWGGYPQAERQRIAIARSEIAIDSASVDMAAIEIAGNFLFDTASHRDFLGAMLGTGIVREKTGDVIVLGERGAQAIVIPEMVEYLEMSLQQVRSVPVKTRRIELSELKIREPKKKEMVTVEASMRLDAVASAGFAMSRSKMVDLIDSGDVRVNWKDITQASHNVKSGDLIAVSGKGRLEIGEVAVTKKERYRVQLTRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F437</accession>
    <name>A0A2G4F437_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2499 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56247">
        <property type="protein sequence ID" value="PHX56247"/>
        <property type="gene ID" value="CP500_006465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019634">
        <property type="entry name" value="Uncharacterised_Ycf49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10693">
        <property type="entry name" value="DUF2499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="11907" checksum="602FF4BF046D743F" modified="2018-01-31" version="1">MHALSIPTWIIHISSVVEWIAAIWLIWTYGEVTQNRAWWALSFGMLPALVSAMCACTWHYFDNSPALEWIVTLQAAMTLIGNFTLWAAAWWIWRSAQPEKIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4C5</accession>
    <name>A0A2G4F4C5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56337">
        <property type="protein sequence ID" value="PHX56337"/>
        <property type="gene ID" value="CP500_006010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="11635" checksum="8230CFCE8CD122B3" modified="2018-01-31" version="1">MNADVFLDKADAVADGYFATWTEPEAMDAVEIVAKALTNVLNCGVQAEKATTNPPKIGGLGTVSIPESDRARALSLPLGVQIIGTPYSEAVILRVAAVLEAQGVVSAKSIDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4F2</accession>
    <name>A0A2G4F4F2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56629">
        <property type="protein sequence ID" value="PHX56629"/>
        <property type="gene ID" value="CP500_004245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="6880" checksum="C9B09EEF9511603E" modified="2018-01-31" version="1">MVEHDFTIPLAVLFVGFVAAVSIGSIAWYNSKRLPGWESKERPDFIPKVDKDDLISESTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4W4</accession>
    <name>A0A2G4F4W4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rimM</name>
        <name evidence="6" type="ORF">CP500_003600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56778">
        <property type="protein sequence ID" value="PHX56778"/>
        <property type="gene ID" value="CP500_003600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RimM" evidence="4">
        <location>
            <begin position="6"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="PRC" evidence="5">
        <location>
            <begin position="98"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="214" mass="23977" checksum="7D25ABF75FD9DA90" modified="2018-01-31" version="1">MSEWIEIGTIVAAQGLDGEVRVYPDSDFPERFVEPGKRWLLFPNKTEPEPIEFLSGRYIPGKGLYAVEVSGVEDRTAAEALRGCKLLVEKSSRPYLEPDEFYVQDLFGMEVFNQLTGELLGKVSEIIPAGNDLLEVELVQTPAEIAATEAERSKIVSVEVQHKDSRRKKHKTPRAKPPQTRKVLIPFVKEIVPVVDLEKGRIEIVPPSGLLDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Y7</accession>
    <name>A0A2G4F4Y7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56799">
        <property type="protein sequence ID" value="PHX56799"/>
        <property type="gene ID" value="CP500_003475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="80" mass="9298" checksum="24C3F79F4D4DFD61" modified="2018-01-31" version="1">MVSIVNKPSSLIHEICIEKVDRWKLFKFSESLQQRMEILLEKKKADQLIAEEIAELEAIGELDRIFTHINAMMVAQDVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Z7</accession>
    <name>A0A2G4F4Z7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF839 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56873">
        <property type="protein sequence ID" value="PHX56873"/>
        <property type="gene ID" value="CP500_003090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008557">
        <property type="entry name" value="PhoX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05787">
        <property type="entry name" value="DUF839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013908584" evidence="1">
        <location>
            <begin position="24"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="783" mass="84574" checksum="A6BEF14D7D0AEF94" modified="2018-01-31" version="1">MSKITRRQLLIFFGSSAATTVLAPQLTETLFGLNSTSAEAAFSPISFTPLRLPHPLPVYQELSSFMPTGLNGQGTVMAASQDTKLTSYSVVDDVVVPPEYERYVILRWGDRVFPDLSDYFGYNNDYTGFVGLRGSNDDGYLWVNHEYVSFPMSKQAPETPTDLASFPATDRAVIGLDLSVKNRATLGEFLYNMGGSIVRITKQANGRFGAIARDPLNRRIHGLSGLGINSQRSDKYKEVTSWGTRQGDDKYLTGTGPAATQVFAQVNSDGLGNQIIGTAYNCSGGTTPWGTILSAEENFQGSELFFVGVQENIKPNGSQTSYAKGTTGEEFGLVGEKYGWMVEVDLQDPNFRPRKHTALGRFRHENVAMRAEAGRKLVVYMGDDRRGGHTWKFVSNGTVTNPADKNNSRLFEDGTLYVAQFNRNGAGRWLPLALNSPTNPVSPKKMGEAELASFGKAQRDANTRLPKRAGIAGQTEDGGSFVVDTTNEATALPGYRNKTLASFYTSQGAVLVDAFLAANLIGGTPTARPEDLEIHPTTKEVFIAYTDGAPGSDGYPDSRIFNVAKYTAALNSGQQSGGIYKIIEDSSDGAGLTFRWQRFVQGGEAGSVSGAGFASVDNLAFDTQGNIWGVTDMSTSTHNGFDVGSAAKQAAIDHKKTGNTSEFTGVFGNNWLFYIPTNGPNAGSVIPFAYGPNRCEITGPTFIGDTLVVAVQHPGEDCPIDDGTVLSRQIEMLDLNGALFNQTRTVSRGSLWPSNISNDSRRSPMPSVIGIRRVRSTTTGQFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F504</accession>
    <name>A0A2G4F504_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56805">
        <property type="protein sequence ID" value="PHX56805"/>
        <property type="gene ID" value="CP500_003515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8564" checksum="2F1D7F7D6BF22B4B" modified="2018-01-31" version="1">MNLTTGLLTRITQTPGQCGGRPCIRGMRIRVTDILEMLAENVSVTEILEDFPDLELADIQACLLFAARRTDFPRLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F579</accession>
    <name>A0A2G4F579_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4079 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56861">
        <property type="protein sequence ID" value="PHX56861"/>
        <property type="gene ID" value="CP500_003025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025067">
        <property type="entry name" value="DUF4079"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13301">
        <property type="entry name" value="DUF4079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="234" mass="26676" checksum="4409D2C0C7B56883" modified="2018-01-31" version="1">MELQDTLALLHPAIAIIVVFPLIGVVVNRALLTRQRRLEVVDGQKSKIPPVVGSEHVAIGNWLSGSVVGVALLGMAYPIFSKMLSNDTLTKEPFRVFFAIAIFLLTIASFALLFKARVKLWRGIFATFTGMGLMILGFQPEIFRRDNEWFVSHYYYGMIASLLMIFSVAIVQDIYQDRQNRWRRVHIILNCLALLFFLGQGMTGARDLLEIPLHWQSKYIYQCDYTNKTCSQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5G9</accession>
    <name>A0A2G4F5G9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56951">
        <property type="protein sequence ID" value="PHX56951"/>
        <property type="gene ID" value="CP500_002945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="204" mass="22843" checksum="4AD2B18B73A9DA67" modified="2018-01-31" version="1">MAQDVRQWLDEIKRLQQQLTEVSRDRDEASESAAQWRQLYNTEAEQRRNDAKLTQQSIANLEAQIQQLQTFSPIVSEGDEAGSARQQEVEQLQTVGELKAKLVVVMEERDRAFEQIKQLTQALKQEEARHAETSKNLTSALGDAVDLLTKAKTPAAVKTETVYSLEIVPVTTGNSGESAIEIRHNPAQLPPSKNQLLQLPPFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5N2</accession>
    <name>A0A2G4F5N2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57082">
        <property type="protein sequence ID" value="PHX57082"/>
        <property type="gene ID" value="CP500_002040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="149" mass="16850" checksum="02DE33B2F892E714" modified="2018-01-31" version="1">MPPLLSKTTDQRIIHHGMWEQFKFIEKGFEGSPGVRLFYYDGTIEILIPGQDHETFAHIIGYLLTTFLVERGIFFWTEAVNNGNPVEYLAQKKAQVADELLQISDKKVENSTRAMVKGAYGKLRPSAKNYVENGIPDLAKIIDKYNSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5R6</accession>
    <name>A0A2G4F5R6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57124">
        <property type="protein sequence ID" value="PHX57124"/>
        <property type="gene ID" value="CP500_001620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="85" mass="9889" checksum="10485EA3080820EE" modified="2018-01-31" version="1">MEEGRRKKEEVRRKKEEGSTTGFILNEVEEFRINPVVGFSAPLRLGTRKQEECLYNKLFTHLYFMLDSAKLNNICSSTTTRPCLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5U1</accession>
    <name>A0A2G4F5U1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpmE</name>
        <name evidence="7" type="synonym">rpl31</name>
        <name evidence="9" type="ORF">CP500_001670</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57132">
        <property type="protein sequence ID" value="PHX57132"/>
        <property type="gene ID" value="CP500_001670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00501">
        <property type="entry name" value="Ribosomal_L31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027491">
        <property type="entry name" value="Ribosomal_L31_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="72"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11285" checksum="E4E1619A93EFAC0C" modified="2018-01-31" version="1">MAKAGIHPEWYPEAQVFCNGEHVMTVGSTRAKLQVDVWSGNHPFYTGTQKIIDTEGRVERFMRKYGMTDVEMPTADANSGPIKMEDPKADAAKAAAKGKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5U6</accession>
    <name>A0A2G4F5U6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tail length tape measure protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_002115</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57095">
        <property type="protein sequence ID" value="PHX57095"/>
        <property type="gene ID" value="CP500_002115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039565">
        <property type="entry name" value="BamD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008939">
        <property type="entry name" value="Lytic_TGlycosylase_superhlx_U"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13525">
        <property type="entry name" value="YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48435">
        <property type="entry name" value="SSF48435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="YfiO" evidence="4">
        <location>
            <begin position="91"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="3">
        <location>
            <begin position="570"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="731" mass="82629" checksum="4FE4CB0E8DD979D7" modified="2018-01-31" version="1">MLKRRKTRFSVLIGVSICVMAIGSLVGAAKLMSIGPFQKAEPAQNAANSDSEVKTLVSLSPTERATQLDAIAVSKSASANQQPASSKSRARYLLATDLIQQGNVTKALTLLDKLEQEYPLLASHIALKRAEAYQLSGDQDKAEKAWQELLKNYPTQPVVAEALYFLGKSKPEYWQQAITQFPAHPRSVEIALAKLKENPNQPQLMLIVAKHGHYVNDYGTILEKLVQQNSSALKPEDWEEIAFGYWEKQDYGKGAIAYGKAPRTAKNLYRKARGLWLDGKIPESKIAYQELISEFPDSEDTGLGLIRLSRLNEPKDAIVLLDRVISSFPNHAPEALLDKSQLLDKLGSATSASETRKLLLTKYNNSDKAGELRWTVAQQFAKGGDVNSAWKWARELTTHNPDSELAPEAAFWVGKWAKQIGREQDAKTAFEYTIIRYPESYFAWRSAALLGWPVGDFTTVRDLSPNVVRPPQRVEPTAGSPILKELYQLGQDRDAWTLWQIEFTNRVEPSISEQFTDGLMRIGVGDNLDGLWMVGSLRQREKPAERKEYLVLRQQPNYWQTLYPFPYLENIVKWSQERQINPLLVTALIRQESRFMPKIKSSVGATGLMQVMPETGAWVAQQINFKKYSLENVDDNIKLGSWYLVHTHDEYKNNSMLAVASYNAGPNAVADWLKRFSFSDADAFAEKIPFPETKGYVKSVFENYWNYLRIYNPEVSKLIRDNYAASQQKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F642</accession>
    <name>A0A2G4F642_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_002400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2Fe2S plant-type ferredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56957">
        <property type="protein sequence ID" value="PHX56957"/>
        <property type="gene ID" value="CP500_002400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010241">
        <property type="entry name" value="Fd_pln"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02008">
        <property type="entry name" value="fdx_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="11478" checksum="9B9B18D53FECC133" modified="2018-01-31" version="1">MSKTYTVEFLHQGSTYTVEVPEDKQLLRAANAAGIELPSSCNSGVCTTCAAKIIEGQVEQTDCMGVSPDLQAEGYVLLCVAFPRSNLKIETEKEDIVYDRQFGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F695</accession>
    <name>A0A2G4F695_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57292">
        <property type="protein sequence ID" value="PHX57292"/>
        <property type="gene ID" value="CP500_000925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="104" mass="11963" checksum="DE11833461F5CA4A" modified="2018-01-31" version="1">MNKMLQNYQKGMSVFDDCHNSTVRSQWVALTDEIGEFVSEPSLSEIWDILHAAGRLFYKLTGVPLNLLAYPTVRKHSQRFEEYGCIRSQRNCEGKCCKQLTVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6G4</accession>
    <name>A0A2G4F6G4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GTPase Era</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">era</name>
        <name evidence="12" type="ORF">CP500_000640</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57362">
        <property type="protein sequence ID" value="PHX57362"/>
        <property type="gene ID" value="CP500_000640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="11">
        <location>
            <begin position="23"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="10">
        <location>
            <begin position="221"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="8">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="8">
        <location>
            <begin position="57"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="8">
        <location>
            <begin position="78"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="8">
        <location>
            <begin position="140"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="8">
        <location>
            <begin position="169"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="78"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="140"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX57362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="315" mass="34989" checksum="D2557B30F68DED3C" modified="2018-01-31" version="1">MEDSKIIDLSEIMSVPVAPAGYKSGFVAIVGRPNVGKSTLMNLLVGQKIAITSPVSQTTRNRLRGILTTDEAQIIFVDTPGIHKPHHQLGKVLVQNARTAIRSVDLVLFVVDGSVESGGGDRYIVEILSNTEVPVILGLNKLDEQPPDCVLIDRTYEQIVNPQWPVVKFSALTGEGVESLQKLLVEHLDVGPYYYPPDLVTDQPERFIMGELIREQILLQTREEVPHSVAIAIEVVEEEPKITRILASINVERDSQKGILIGKSGTMLKSIGSAAREQIQKLIEGKVYLELFVKVQPKWRQSRTRLAELGYRVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6J3</accession>
    <name>A0A2G4F6J3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aspartyl protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57107">
        <property type="protein sequence ID" value="PHX57107"/>
        <property type="gene ID" value="CP500_001500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="128" mass="14264" checksum="E423381949414B65" modified="2018-01-31" version="1">MISGRFGENGQLFFEIELIASNGDNFSVEVLLDTGFTTGFLAINSQDLDALDWSLIAPQIEMQTARGECFFDIYEGRVIIDGQELIVLVHVGEDLPEILIGSQWLDRMQLVVNKPRGILTLETVSSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6L7</accession>
    <name>A0A2G4F6L7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cob(I)yrinic acid a c-diamide adenosyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57398">
        <property type="protein sequence ID" value="PHX57398"/>
        <property type="gene ID" value="CP500_000205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="178" mass="19649" checksum="38BE0B050A895CCE" modified="2018-01-31" version="1">MIAQLKTPNLNLTHSLPYTVAGLVQVFTGPHRCFFTTVMAQALRIAGQGTAVLAVQFLKGGINQGHQHPMRLGQNLDWVRCDLPRCIDNADLDELELGAIAQLWQYVQEVVREGRYALVILDELSLAVNLGLIPEAEVLALIDSKPHHLDLIFTGPSMPQGILDVADQITEIRRTQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6N6</accession>
    <name>A0A2G4F6N6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell division protein SepF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sepF</name>
        <name evidence="7" type="ORF">CP500_000400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Localizes to the division site, in a FtsZ-dependent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SepF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57454">
        <property type="protein sequence ID" value="PHX57454"/>
        <property type="gene ID" value="CP500_000400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01197">
        <property type="entry name" value="SepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023052">
        <property type="entry name" value="Cell_div_SepF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007561">
        <property type="entry name" value="Cell_div_SepF/SepF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038594">
        <property type="entry name" value="SepF-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35798">
        <property type="entry name" value="PTHR35798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04472">
        <property type="entry name" value="SepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0717">Septation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="204" mass="22211" checksum="5DFE872EC81E45A7" modified="2018-01-31" version="1">MNIFSKLKDFVGFNNEEEYDDQYGELEEARYQNVYQPPEPNPAAVAAAEERRQSRRMQERSVVGSTGTDVVSPIGGVGTVMNNVIGMPGAMNGVSEVVVMEPRTFEEMPAAIRALKERKSVVLNLTIMDPDQAQRAVDFVAGGTYALDGHQERIGESIFLFTPSCVQVRTQSGVVHEVASAQGRPRTAAPAPTVWPAEQAQAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6P2</accession>
    <name>A0A2G4F6P2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)H-quinone oxidoreductase subunit N</fullName>
            <ecNumber evidence="7">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(P)H dehydrogenase I subunit N</fullName>
            <shortName evidence="7">NDH-1 subunit N</shortName>
            <shortName evidence="7">NDH-N</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ndhN</name>
        <name evidence="8" type="ORF">CP500_001820</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cellular thylakoid membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the complex I NdhN subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57157">
        <property type="protein sequence ID" value="PHX57157"/>
        <property type="gene ID" value="CP500_001820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01353">
        <property type="entry name" value="NDH1_NDH1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020874">
        <property type="entry name" value="NAD(P)H-quinone_OxRdtase_su_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35515">
        <property type="entry name" value="PTHR35515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11909">
        <property type="entry name" value="NdhN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0520">NAD</keyword>
    <keyword evidence="2 7" id="KW-0521">NADP</keyword>
    <keyword evidence="3 7" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="1 7" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 7" id="KW-1278">Translocase</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="158" mass="17190" checksum="9FEDD856AEADB5FC" modified="2018-01-31" version="1">MGLITTGSDMIRDLEKSGSLALYVPLEGGFEGRYLRRLRAAGYGAYNITARGLGDLAMYLTGVHGVRPPHLGKKTTGNEAAVGYTYYVPPLLQTQLDNLPAKAKGLVLWIIEGQILSSQEVEYLTVLPTLEPRVKIAVEMGGDRVFSWKPLKDALVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F707</accession>
    <name>A0A2G4F707_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_000130</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57387">
        <property type="protein sequence ID" value="PHX57387"/>
        <property type="gene ID" value="CP500_000130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="219"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="280"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="455"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="722" mass="80938" checksum="B4AA85F228A4D2D5" modified="2018-01-31" version="1">MLAILNKIGEIIARWWSEFTLQTRLMAAATLVVSLIMSGLTFWAVNTIQQDARLNDTRYGRDLGLLLSANVAPLIAKNDRSEVARFSHQFYSSTSSVRYMLYADEAGDIFLGIPFSKSEVQTSLTLRRQIKLPDSFIADIEARNLTSVPLVRQHLTPDGEVTDVFVPLIHEDKYLGVLAIGINPNPAAVVYSNLTRDVTLAVFVTIWVMVILGAVFNALTITKPIKQLVFGVKNIASGNFKQRVDLPLGGELGELIGSFNEMAQKLESYEEQNIEELTAEKAKLETLVSTIADGALLLDANLQVILVNPTGRRIFGWEGKNAIGVNLLHILPAEVQQDLTRPLQEIAAGDREGGEFRISMREPVNRTIRIVLTTVILHKAPGAESLCKSCVRDEENNCDNSDRPEVVECTFYEQTSKHQGSSGQYRESLKGIAMTVQDITREVELNEAKSNFISNISHELRTPLFNIKSFIETLYEYGEDLQESERREFLEIANRETDRLTRLVNDVLDLSRLESCRIYQMDAVDLHQAVEQTLRTYQLNAKDKGIELNQEVDPDLPSVLGHYDLLLQVLANLVGNALKFTESGGQISIRAYVLEEKTTQHKDSASGKYNHLPASRQSPAVRIEISDTGIGIDSEDQQAIFERFFRVENRVHTLEGTGLGLSIVRNIIDKHHTKINLVSEVNVGTTFWFDLAVYQQKKTLEMENPWPVEAKVETETISTHVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUL2</accession>
    <name>A0A2G4EUL2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit beta</fullName>
            <ecNumber evidence="11">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F1 sector subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">atpD</name>
        <name evidence="11" type="synonym">atpB</name>
        <name evidence="13" type="ORF">CP500_022885</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cellular thylakoid membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000251">
        <property type="protein sequence ID" value="PHX53178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53178">
        <property type="protein sequence ID" value="PHX53178"/>
        <property type="gene ID" value="CP500_022885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 11" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="154"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="162"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX53178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="485" mass="52025" checksum="DDD7367B0D399220" modified="2018-01-31" version="1">MVSTAVKTNVGYITQIIGPVVDVKFPGGKLPQIYNALTISGKNQAGQDVSVTCEVQQLLGDSQVRAVSMSTTDGLVRGMEAVDTGRSIQVPVGIPTLGRIFNVIGEPVDNLGPVDTTESMPIHRNPPAFTELETKPSVFETGIKVIDLLAPYRRGGKIGLFGGAGVGKTVIMMELVNNIAKAHGGVSVFGGVGERTREGNDLYKEMIESGVINEEDRSKSKIALVYGQMNEPPGARMRVGLSALAMAEYFRDVSKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDMGDLQERITSTTEGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQVSVVGAEHYGVARQVQSTLQRYKELQDIIAILGLDELSEDDRLTVSRARKIERFLSQPFFVAEVFTGAPGKYVKLADTIKGFQMILAGELDELPEQAFYLVGDISEAIAKAEKMKADAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUM3</accession>
    <name>A0A2G4EUM3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YqeG family HAD IIIA-type phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000235">
        <property type="protein sequence ID" value="PHX53231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53231">
        <property type="protein sequence ID" value="PHX53231"/>
        <property type="gene ID" value="CP500_022605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010021">
        <property type="entry name" value="PGPP1/Gep4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF25">
        <property type="entry name" value="PTHR19288:SF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01668">
        <property type="entry name" value="YqeG_hyp_ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="18910" checksum="96CE30BB81D19F85" modified="2018-01-31" version="1">MSWGKLLQPDLVLGTAVVNLTADILEKYQIKGLVLDVDETLVPITAANASPELSLWVEEIKPVVSVWLASNNLSQNRIGRIAASLNLPYITGAAKPSRRKLRRALDAMDLPVEQVAMVGDRLFTDVLAGNRLGMFTILVEPMVDAGDAVRKYPVRSFEVWVSQALGASLKIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUS1</accession>
    <name>A0A2G4EUS1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase epsilon chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP synthase F1 sector epsilon subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">F-ATPase epsilon subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atpC</name>
        <name evidence="11" type="ORF">CP500_022895</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 8">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cellular thylakoid membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000251">
        <property type="protein sequence ID" value="PHX53180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53180">
        <property type="protein sequence ID" value="PHX53180"/>
        <property type="gene ID" value="CP500_022895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020547">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="PTHR13822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00401">
        <property type="entry name" value="ATP-synt_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01216">
        <property type="entry name" value="ATP_synt_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0139">CF(1)</keyword>
    <keyword evidence="7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 7 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 7 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_DE_N" evidence="10">
        <location>
            <begin position="3"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_DE" evidence="9">
        <location>
            <begin position="85"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="14555" checksum="0EE6CBA55CBD3AF0" modified="2018-01-31" version="1">MTLTVRVVAPDKTVWDSDAEEVILPSTTGQLGILSGHAPMLTALDTGVMRVRPGKEWVSIALMGGFAEIQENRVTVLVNGAEKGDKIDKETARTAYTEAEARLEKSANGTLQEQIQAKQAIKRARARFQAAGGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUW8</accession>
    <name>A0A2G4EUW8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MinD/ParA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53333">
        <property type="protein sequence ID" value="PHX53333"/>
        <property type="gene ID" value="CP500_022025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="2"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="252" mass="27585" checksum="20E6044D114C8563" modified="2018-01-31" version="1">MSKIISVHSYRGGTGKSNTTANLASIVASQGNRVAIVDTDIQSPGIHVLFGFSENNMDRCLNDYLWGRCAIADTACNVSSLLPKLADKGELYLIPSSIKAGEIARVLREGYDVGLLTDGFQELIEVLNLDYLFIDTHPGLNEETLLSITISDILLLILRPDQQDFQGTAVTVDVARQLEVPKILMTINKAPESLDFDDLKQQVETIYKIPVTGVLPHSDKMMLLASKGVFALHYPNDPLTKVVEGIAQQIMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUX1</accession>
    <name>A0A2G4EUX1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endolytic murein transglycosylase</fullName>
            <ecNumber evidence="7">4.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Peptidoglycan polymerization terminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mltG</name>
        <name evidence="8" type="ORF">CP500_022600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transglycosylase MltG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000235">
        <property type="protein sequence ID" value="PHX53230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53230">
        <property type="protein sequence ID" value="PHX53230"/>
        <property type="gene ID" value="CP500_022600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08010">
        <property type="entry name" value="MltG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02065">
        <property type="entry name" value="MltG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00247">
        <property type="entry name" value="TIGR00247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="41531" checksum="B25F01C7BF86C833" modified="2018-01-31" version="1">MDQEQLTKDSARQSRKGTPQVSKWLFYLALLPAIWGVCAWQGWAWWSWASAPPKLAAESTTPSDATAVSIQIPEGTSSQKIGRDLEAAGLIRSASAWNMWARWLTLQNREGGFKAGTYQLSPTQPLGAVADKLWKGEVVQQSFTIPEGWSLTQMSTYFEAQGFFPAKSFMAAVSQVPYAEYPWLPSGLPHLEGFLYPDTYQLDGDTVTPEAVIKQMLGRFEQVALPVYQKNQKNTKLDLKEWVTLASIVEKEAVVASERNRISGVFNSRLKKSMPLASDPTVEYGLGIRQTKEKPLTFKQVETPSPYNTYINVGLPPTPIAAPGIASLEATLAPENTEYLYFMARYDGTHIFSRTLAEHNAAVAQIDQKVRSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV62</accession>
    <name>A0A2G4EV62_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000216">
        <property type="protein sequence ID" value="PHX53320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53320">
        <property type="protein sequence ID" value="PHX53320"/>
        <property type="gene ID" value="CP500_022135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="243" mass="25910" checksum="8F03BD583487EDDD" modified="2018-01-31" version="1">MVTIKCRGITFSNIQAIIFDKDGTLEDSQEFLRHLGLKRSRLVDAQIPGVGEPLQMAFGIEAGKIDPTGLMAVGSRKENEIVAAGYIAETGRGWIESLAIAQRAFDEADQMLKNSPPSPLFVGSLEVLKSLSEAGLKLGILSAATTEAVEKFVKTYQLSDYIQLEMGVDSVQLNKPDPRLFLLACERLGVDPAATLMVGDSAGDIQMGRDAGAAGCIGICWGAAEVSHLEKADVAIASLDEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV81</accession>
    <name>A0A2G4EV81_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53435">
        <property type="protein sequence ID" value="PHX53435"/>
        <property type="gene ID" value="CP500_021475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="269" mass="27882" checksum="FE39BB00A0345DCF" modified="2018-01-31" version="1">MALKADNSGIARLVGDNSPENITLTPGQLANFPGGVWLLGGNDTVQGSSDAERIFGNDDKDSLLGGAGNDSIYGGKGDDDILGEIGNDFLTGDRDSDFLDGGAGNDLLRGGQGIDLLVGGDGNDTLIGDRDVDIYKGGAESDIFVLRVDQAGEKIIGFEVPDAVIVDFDKSNDSIGISVAFTSSNISFEQVNYSLNDPRLLLLNPATVADGTSLLAKGGISQQNLDPDGNGRVEATNIRFGVTNALLGTMLNVTPADLTGRFINASSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVJ7</accession>
    <name>A0A2G4EVJ7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000177">
        <property type="protein sequence ID" value="PHX53563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53563">
        <property type="protein sequence ID" value="PHX53563"/>
        <property type="gene ID" value="CP500_020840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="261" mass="29143" checksum="7F9E6710BC7D2615" modified="2018-01-31" version="1">MNHTSDSNSPLDDFMQSLGLDPHQPNNLDHSHNNLHLNDHNLNHPATSDITHSDWTDSSHNLSQQHPQSDWTHSNDIHHTDNQWQNPEYGFATGISATPSDWTDTSHNFHQQNHQSDWTHSHDIHPTDTHQHNSETGFASATNHHDTHTNAAPHVVNSSYSNSGDGPFIHIDRSGDVHLHKLDGTTQVVGHVDGRDFYNSASEHIGYLSKNGHICRWADDTSVGRVESGHIYRENGKEVGRADTDLEGAAHMLFAVRGGTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVM0</accession>
    <name>A0A2G4EVM0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1778 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53581">
        <property type="protein sequence ID" value="PHX53581"/>
        <property type="gene ID" value="CP500_020785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014795">
        <property type="entry name" value="Vibrio_phage_ICP1_Orf50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35401">
        <property type="entry name" value="PTHR35401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08681">
        <property type="entry name" value="DUF1778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="133" mass="15029" checksum="E4C39EDD8BE292FD" modified="2018-01-31" version="1">MTLENLEAEVLALPKDSQAALLSRLLELLERGEIDREVGSIGVEEAQRRDLIINIRMNQPQSDLIDRAAQIQGKSPAEFMVDSAYQKAQDVLLDRCFFGLDEVKFKEFVALLDAQPMGNEKLHTLLTTKSLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVM7</accession>
    <name>A0A2G4EVM7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Allophycocyanin subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">apcB</name>
        <name evidence="13" type="ORF">CP500_020645</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cellular thylakoid membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53585">
        <property type="protein sequence ID" value="PHX53585"/>
        <property type="gene ID" value="CP500_020645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12126">
        <property type="entry name" value="APC_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006245">
        <property type="entry name" value="ApcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34011:SF3">
        <property type="entry name" value="PTHR34011:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000081">
        <property type="entry name" value="Phycocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01337">
        <property type="entry name" value="apcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="11 12" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="8 12" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 12" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="2 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX53585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="161" mass="17317" checksum="BCB98FFBE9561024" modified="2018-01-31" version="1">MQDAITAVINSSDVQGKYLDISALDKLKNYFASGELRVRAATAISANAATIVKEAVAKSLLYSDVTRPGGNMYTTRRYAACIRDLDYYLRYATYAMLAGDPSILDERVLNGLKETYNSLGVPIGSTVQAIQAMKEVTAGLVGSDAGKEMGVYFDYISSGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVN7</accession>
    <name>A0A2G4EVN7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipA</name>
        <name evidence="8" type="ORF">CP500_020610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000174">
        <property type="protein sequence ID" value="PHX53603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53603">
        <property type="protein sequence ID" value="PHX53603"/>
        <property type="gene ID" value="CP500_020610"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="67"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="325" mass="36009" checksum="15263309E93E3097" modified="2018-01-31" version="1">MLPQTPQTPAAKLTASQMRAEIELMPEWLRRPIGKASELSEVQKIIKQRQIHTICEEGRCPNRGECYAQKTATFLLMGPTCTRACAFCQVDKGHSPMPLDPEEPQKVAEAVNILGLRYAVLTSVARDDLPDGGAGWFAMTIAAIRQLSPHTQIEVLTPDFWGGAVSAAQTGRGGAPVPALPLDELQRSRIQTVVEAKPACYNHNIETVRRLQGPVRRGAKYDRSIDVLRIVKQFDSSIPTKSGLMLGHGETEAEIIEAMADLRDAECDRLTLGQYMRPSLEHLKVQKYWTPAEFDHLGEIAREMGFQQVRSGPLVRSSYHAGEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVQ2</accession>
    <name>A0A2G4EVQ2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-dehydroquinate synthase</fullName>
            <shortName evidence="8">DHQS</shortName>
            <ecNumber evidence="8">4.2.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroB</name>
        <name evidence="10" type="ORF">CP500_022505</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000230">
        <property type="protein sequence ID" value="PHX53247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53247">
        <property type="protein sequence ID" value="PHX53247"/>
        <property type="gene ID" value="CP500_022505"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00110">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030963">
        <property type="entry name" value="DHQ_synth_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001455">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="9">
        <location>
            <begin position="69"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="107"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="131"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="364" mass="39222" checksum="76ABC592FBA938A1" modified="2018-01-31" version="1">MQSVIKVDLGPQSYNVCVRSGGLDELGSLMGGLNLGKKVLLVSNQSIFRHYGERATAGLESAGFQVDNCILPPGEQYKTLNSVQKIYGAALENRLERSSTMVALGGGVVGDMTGFAAATWLRGINVVQVPTSLLAMVDAAIGGKTGVNHPLGKNLIGAFHQPRLVLIDPDVLKTLPAREFRSAMAEVIKYGVIWDVELFEKLESCKRLDQMRYVKADLLAEILSRSCQAKADVVSKDEKESGVRAILNYGHTIGHAVESLTGYKLVNHGEGVAIGMVASSRLAVELGMWDAECDGRQLDLLAKAGLPTKLPAGMDVEEILKSLQLDKKVQDGKVRFVLPVRLGEAAVSNRVDGDVIIQVLKEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW09</accession>
    <name>A0A2G4EW09_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000208">
        <property type="protein sequence ID" value="PHX53367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53367">
        <property type="protein sequence ID" value="PHX53367"/>
        <property type="gene ID" value="CP500_021860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013713716" evidence="1">
        <location>
            <begin position="20"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="257" mass="27620" checksum="C4BFF4682A4FD73E" modified="2018-01-31" version="1">MKRRQLIRYAQTSLLAAFATGLPSGWDSYQAQNADSLSVQWLGHTCFLFTGGGARVLVNPFRPLGCTAGYRAPKVPTDLILISSRLLDEGAVDGFSGNPGLLYEPGTYQSNGLRLQGIRMQKDREGGRRFGLNVAWLWQQAGVKILHLGGVAGPIGIEEQILIGRPDVVLIPVGGGPKAYTPAEAKQTLQLLKPKMVIPTHFKTQAADAAACDLVTLDDFLALMDGTTVRRSNNDTLSVRSATLPASGSVIEVLSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW18</accession>
    <name>A0A2G4EW18_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_020310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000166">
        <property type="protein sequence ID" value="PHX53656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53656">
        <property type="protein sequence ID" value="PHX53656"/>
        <property type="gene ID" value="CP500_020310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="149"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="220" mass="24728" checksum="D9C3327ADCEB6243" modified="2018-01-31" version="1">MERILVVDDEADCQTVLGMYLESQGYRVQCATSGIEALSIFENDPPDLVISDVMMPEMDGFEFCRRLRNTRLGKLMPFIFLSGQGEIESKVEGHSIGADDYLVKPFQSEEILAKVKAQLERSHRIHAEIVRLLQNSTALTVEPKILPVAPPAPLPLTPAEERVFGEVIQGYTNKQISHRLFISPRTVQAHLGSIFSKLHIENRAQLVKFALERGYKPPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW20</accession>
    <name>A0A2G4EW20_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aldose epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53725">
        <property type="protein sequence ID" value="PHX53725"/>
        <property type="gene ID" value="CP500_019880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="292" mass="32989" checksum="55B7B5300C4F9DA6" modified="2018-01-31" version="1">MTSQFAIALKQKQYKTYVLSDETANSVLEIVPERGGIATSWLVEGKEIFYLDTERFTNPDLTVRGGVPILFPICGNLPDDTFTHKGEKWKLKQHGFARDLPWTVGEVATKGSAALTLILDSNEKTQAVYPFDFRLAFTYQIKGNSLEIFQRYINLSEEPMPFSSGFHPYFLAPDKSKLRFEIPGMQYRDQNTHSKGYFTGVFDQTLDEIDVSFDELTGLAATVTDSSRDLRLTLSYNSSYGKLVFWMLKGKDFYCLEPWTAPGNALNTGAHLIYLPPGATCEMLIRMTATFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW56</accession>
    <name>A0A2G4EW56_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4058 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53751">
        <property type="protein sequence ID" value="PHX53751"/>
        <property type="gene ID" value="CP500_019755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025132">
        <property type="entry name" value="DUF4058"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13267">
        <property type="entry name" value="DUF4058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="258" mass="29039" checksum="374429676DF95B2B" modified="2018-01-31" version="1">MPSPFPGVDPYLENSEFWPEVHHRLITAIAIAIGPALRPKYRVAIEKRIYLSDAEDSDFLAIPDVTIFSKPSTGGQSTATATLLHPEPITVTVPILEEAREGYLELREVGTNRVITVIEILSPKNKRAGKGREEYENKRQEVLRSASHLVEIDLLRAGKPMPMTGGTNTDYRILISRGNRRPRAQLYAFTVREEIPPFLLPLQPGDAEVYVELQSLFAEIYDQAGFDLSLDYTQAPVPRLKEEDAVWADAFLREKGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWK9</accession>
    <name>A0A2G4EWK9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable nicotinate-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nicotinate mononucleotide adenylyltransferase</fullName>
            <shortName evidence="6">NaMN adenylyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">nadD</name>
        <name evidence="8" type="ORF">CP500_019015</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NadD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53909">
        <property type="protein sequence ID" value="PHX53909"/>
        <property type="gene ID" value="CP500_019015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00482">
        <property type="entry name" value="TIGR00482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="6"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="221" mass="24297" checksum="6FDD0A297385A2B1" modified="2018-01-31" version="1">MQKVAILGGTFDPVHYGHLLMAQIAVGQVAIDRVVWAVDRTPPHKSHSVLASFEQRREMVALATAGRPDFGLLPLDTNLSATGAIDSLLYLQNLYPEAQLYWIIGADAFQTLAKWPRCREIGGLCEWLVAGRETAGVDVGLMGRSIDSAGDDDMLVRTQTVCSVVATQMAVRGVQIRWQVLAMPAIEVSSSLIRCYYNEGRAIGHLVPKAIETYIMTHQLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWR6</accession>
    <name>A0A2G4EWR6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000145">
        <property type="protein sequence ID" value="PHX53880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53880">
        <property type="protein sequence ID" value="PHX53880"/>
        <property type="gene ID" value="CP500_019135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="190" mass="22248" checksum="83B6C4C4DDF99F40" modified="2018-01-31" version="1">MENTLVTTRRQRVLTRTQERRQATPKEKELIHLLANMACSLVKYDDQHASGKQVLAPSERKLLAEWHYLRVQQIRRIERSLEPVATLKRVYYKSILSPRDLKSLKLLWLEEDKNRVKRVDPDLDDILSEALDRGDTLKQLFHSIEVKDREFSATACPGVVPLWVKEWELSGYDINYFPPSFSAWVSLVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX02</accession>
    <name>A0A2G4EX02_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_018665</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000135">
        <property type="protein sequence ID" value="PHX53970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53970">
        <property type="protein sequence ID" value="PHX53970"/>
        <property type="gene ID" value="CP500_018665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037783">
        <property type="entry name" value="Taf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="PTHR19879"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="10"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="552"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="594"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="635"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="677"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="719"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="761"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="803"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="309"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="836" mass="93109" checksum="203D59670131C556" modified="2018-01-31" version="1">MVSQLLDGRYQIIEVIETGEFGLTYLAKDTRRPGEPQCFVKHLRPGTSEPKLINATRRLFQKEAEVLERLGLHDQIPQLFAYFEENEEFFLVESFVAGHSLSTEIVPGKPVPEERIIPLLKELLEILVFVHGQGVIHRDIKPGNLIRRYSDNKLVLIDFGSVKEIHIAQRQAPVTVRIGTLEYMPIEQFQYNPQVNSDIYALGMIGIQAITGLPAYDLPKLRDLKNSNKGEIIWRHLTACSQGLADVLDNMVRYDFRERYQSAAEALADLRKIGDRTRARIPKLTIYREEVDRRTSSRGDITVVGRRILEELSVSLELLPEEAEAIEDEVLNPYRKYREKGERYEQALQEAMQQEYPFSMGTREELKRLQQVLGLTDEDATKIEELVVPKSLFSKLYKAIATVLEGHRKSNSPPPESISPLNLQPSPTTPLPLNLNGKTNFPLQNTPAITQKETRKFNPFLAGAALAAILAAIGGIYGYLKWQEWQQWQQRVQRESQQLNQINALYQASNYAGCIGEIPNISNASSSYASAQNLEGQCQAGLRWKNAKVKNFAQHSNAVGAVAFSPDGLMLASGSKDKTIQIWDLATGKSLRTFEGDSSTIWSVTFDSNGRRLATGSGFWRVMLWDIKTGQLIRTLDHTASVWSVAISRDGELIASGSGDKTTKIWNAENGSLIHDLPDHTDFVYSVALTPDGKTLVSASKDKKITIVDVATGRLIKTLDGHADAVRSVAISPDGKTIVSGAYDETIKVWNLETGELIRSLKGHSDDIVSVAISPDGKFIASGSKDKTIKIWDLGTGELLNTLTGHSDEVYVVTFSPDGKTIASGSKDHTIKLWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX06</accession>
    <name>A0A2G4EX06_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3598 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54008">
        <property type="protein sequence ID" value="PHX54008"/>
        <property type="gene ID" value="CP500_018390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022017">
        <property type="entry name" value="DUF3598"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005527">
        <property type="entry name" value="MinE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33404">
        <property type="entry name" value="PTHR33404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12204">
        <property type="entry name" value="DUF3598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="SSF50814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3598" evidence="1">
        <location>
            <begin position="3"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="284" mass="32198" checksum="CC17A0778C0CFE36" modified="2018-01-31" version="1">MGSQWENFLQNLGEWHGSFTQLSPRGEVVQDTPSIIALEGLNDNKTVRLKLQRFYPNSSGVGEPEVSELVREYQTLGRDILFFENGAFCQGTIQIAPFAESGAEFSFIYNYRRLRFVQLYNTNGDLSKLTLIREKQPDKNVPERPPLTIDDLLGEWHGEAVTMYPDWRNPDCYSTKLQLHLDGADRLIQQITFGTNPDAQIITSGGIIDGSVINFNEGTTPMQVLLLPDGGSCTIPVKVELRKSVFFEAGWLVEPDLRFRMIRSYNDKGEWVSLTLVTERKVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX47</accession>
    <name>A0A2G4EX47_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PEP-CTERM sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000130">
        <property type="protein sequence ID" value="PHX54046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54046">
        <property type="protein sequence ID" value="PHX54046"/>
        <property type="gene ID" value="CP500_018260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07589">
        <property type="entry name" value="PEP-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEP-CTERM" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="19342" checksum="54D59930EB89E93E" modified="2018-01-31" version="1">MNGADWFTTKTGTYDTGYGADNLANRWFQDVFAANGFSSVINVFGSTIYNTGLNAGLFQRFSDPNVSYVNQDTATSDIKIGLAGHFDAKTLLLKALPSSVVANFGTTPLQASEVIKLTYGGVTQYKYSFSATGSGLTASDDGISHNGNYELTVQPVPEPTTMLGLALGASGLLAAKRKRSKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXH8</accession>
    <name>A0A2G4EXH8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54244">
        <property type="protein sequence ID" value="PHX54244"/>
        <property type="gene ID" value="CP500_017220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="996" mass="98852" checksum="64A1C052630301DD" modified="2018-01-31" version="1">MPSAVSFFFLETGTDPSSIGTTTSSTGTTTSSTGTTTSSTGTTTSSTGTTTSSTGTTTSSTGRTTSSPGTTTSSTGTTTSSTGTTTSSTGTTAISIAPVSRPTPIAPPTPPPPIFVDGIVVATSTTEYLIGSLFNDTISARAGDDTILGRDGDDLLKGEDGNDSLNGGAGKDIVDGGPGNDTTRGGKDDDLVIGDRGNDQVFGDQGNDTVLGTEGDDTLFGGKGNDSLRGGAEDDLIFGDKGNDTVFGDTGNDCLQGGAGSDLLFGEEGGDIISGGVGNDTADGGEGDDRLFGGDGNDAVIGGAGDDFLAGDRGADTLTGGDGADIFVLGRVGTSAGGSGFLTTGGPGIGDADLIRDFKAGDAIGLAGGLSFTDLEISQGQGSNSSNTIIKDKRTGEFLAVLIDVRSNALDESKFTTAKIPPVDSNPFIIQGTTTSTTGTTTSTTGTRTSTTGTTTSTTGTTTSTTGTTTSTTGTTTSTTGTTTSTTGTRTSTTGTTTSTTGTTPASTTTTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPGTLPTLVPSPSPTPSTSSSIVPTPTLPSPTPPAFPSATPNQPPIVESGKTITGLQNLPFSLSISAPSDPEGQSLSATVTLLPNPIFGLVVTGTIPIAVNQKLTVQELVGLNFQPATNAIGQAGSFSYSVTDEQGGVASAAVAININSFNTSANAALGPIAGDDGIIFTNTNNLLPTFIDVLANDGSPQSGKLNIINVGTPKLGIAVNLVSQVQYIPGTLPGSTTFTYNISDGFGTTPGTGVVSVQILPADSEPNNLIGGSLADNFNGLAGSDTIDGRGGNDTMNGGLDNDVLIGGFGADTMTGGGGSNQFRYTSPDSGGPNFDAASAAAINAAIAAGGYDLITDFTGLGVPIADLFNFAPGFGNVTSINQVLLPVKTTVSSNILGGTAFLFAYDTGGNTYIIYDGNGNNLTGSDSRILAKLNGVTGVSSQSEFDFTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXM4</accession>
    <name>A0A2G4EXM4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54285">
        <property type="protein sequence ID" value="PHX54285"/>
        <property type="gene ID" value="CP500_016975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.40.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007899">
        <property type="entry name" value="CHAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038186">
        <property type="entry name" value="CHAD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05235">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00880">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51708">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAD" evidence="1">
        <location>
            <begin position="13"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="336" mass="38436" checksum="00DBB48A5C48ECE9" modified="2018-01-31" version="1">MNLQTSTKIKTQVKTLGDVAAGAIEKYFHKTIAHEADVLKDKDAEELHQMRVGLRRLRSAVTGFAPVLDFPKQAKEHKIGKVGRILGTLRDLDVMLENLQNRYYPNLPIEEQKILDQALLTLLKQRRRALKGVRAILDRKTYELLKKSIEDWLDKPKFRAISNLPIADVLPDLLLPQVSEFFLHPAWLLGTEYQDGEVKVCDDLNAESVEQKLAAEGKILHDLRKQAKKVRYLMNLFGDFYGESYEVYVEDVKAVQECLGDIQDSEVLGDFLTDFVECDLKKELPQLAGILAENRYAAWGKWQILQRRYLNGEIRQDLRSALIHPVLTDDANLKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXP4</accession>
    <name>A0A2G4EXP4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54305">
        <property type="protein sequence ID" value="PHX54305"/>
        <property type="gene ID" value="CP500_016860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="14029" checksum="FC9C7874FFD87F19" modified="2018-01-31" version="1">MSGLFEILNKIHKKPGMYIGRASASDLFMFIVGYRTAREELGFEPTEKEMEFYGDFQPWLQKRYEVSTSGSWARIIEFYTNNEERAFYRFYELLDEFLQRDSHSKVAQVKEKVGNVTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXQ5</accession>
    <name>A0A2G4EXQ5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Geranylgeranyl diphosphate reductase</fullName>
            <ecNumber evidence="3">1.3.1.83</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Geranylgeranyl reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">chlP</name>
        <name evidence="10" type="ORF">CP500_017350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3 NADP(+) + phytyl diphosphate = geranylgeranyl diphosphate + 3 H(+) + 3 NADPH</text>
            <dbReference type="Rhea" id="RHEA:26229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:75434"/>
            <dbReference type="EC" id="1.3.1.83"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Porphyrin-containing compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the geranylgeranyl reductase family. ChlP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.83" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54230">
        <property type="protein sequence ID" value="PHX54230"/>
        <property type="gene ID" value="CP500_017350"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102067">
        <property type="term" value="F:geranylgeranyl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045550">
        <property type="term" value="F:geranylgeranyl reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010253">
        <property type="entry name" value="BchP_ChlP_pln/prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011777">
        <property type="entry name" value="Geranylgeranyl_Rdtase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011774">
        <property type="entry name" value="Geranylgeranyl_Rdtase_pln/cyn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02023">
        <property type="entry name" value="BchP-ChlP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02028">
        <property type="entry name" value="ChlP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02032">
        <property type="entry name" value="GG-red-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="9">
        <location>
            <begin position="4"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="406" mass="44895" checksum="FD7BFDF5AAB28B52" modified="2018-01-31" version="1">MTLRVAVVGSGPAGSSAAETLVKAGIETYLFERKLDYAKPCGGAIPLCMVQEFDLPQSIIDRQVRKMKMISPSNVEVDINIENAHEYIGMCRREVLDGFLRDRAASLGAKLINGTVHTLEIPGNNKDPYILHYADHSSGEAMGIQKTLKVDLVIGADGANSRVAKAIDAGDYNYAIAFQERIRLPEDKMAYYHDLAEMYVGDDVSTDFYAWVFPKYDHVAVGTGTMKVNQASIKKLQAGVRARAAKRLMGGEIIKVEAHPIPEHPRPRRVVGRVALVGDAAGYVTKSSGEGIYFAAKSGRMCAETIVEISQQGTRIPTEQEIKLYLKRWDKAYGITYKVLDILQRVFYRSDATREAFVEMCADRDVQKLTFDSYLYKTVVPANPFIQMKITAKTIGSLLRGNALAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXT5</accession>
    <name>A0A2G4EXT5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000110">
        <property type="protein sequence ID" value="PHX54288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54288">
        <property type="protein sequence ID" value="PHX54288"/>
        <property type="gene ID" value="CP500_016900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007569">
        <property type="entry name" value="DUF559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04480">
        <property type="entry name" value="DUF559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF559" evidence="1">
        <location>
            <begin position="13"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="133" mass="15607" checksum="67D83DB3705EC85C" modified="2018-01-31" version="1">MTKLYNRSSEKFKRQQLRREMTPAEKELWKRIRNRQLENCKFRRQYSVAAFVLDFYSPEIKLALEVDGDSHFVDGAVEYDAERQEFIESARIHFLRFTNDDVYHNLDGVLEVIVEGIKSLRTSGVLPPPAPPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXV0</accession>
    <name>A0A2G4EXV0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54362">
        <property type="protein sequence ID" value="PHX54362"/>
        <property type="gene ID" value="CP500_016540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013733996" evidence="1">
        <location>
            <begin position="29"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="557" mass="62892" checksum="9B8F2DAA4C594599" modified="2018-01-31" version="1">MTIRLFGRLRRREFIRAFLIGLVAPFFAKTAASSQNYSSLEKSAIATNLTALENQKPGTADWQLTNPAIKREIEGYASLTSVNRGDAIKLFVNTNEPNYTIDIFRMGWYNGLGGRRMNDPIIRKGIRQSPPQEDEASGLIECHWQDPYIWQIPDRTDDWTSGIYLAKLTASKTGKQSYIIFVVRDDDRKSDLLFQSSVTTFQAYNNWGHKSLYRWNSRGKQAYKVSFNRPYAMSPNRNAAYGMGAGEFLTNFQPKRRTSSGGWEYNMVRWLEKEGYDVTYATNIDTHFNTRLLLSHKAFLSVGHDEYWSRDMRDNIETARDKGVSIGFFGSNICYWQIRLEPSRITGEVNRTIVGYKEMADLDPMGGLTQPVGTVDLPVEIAASGELKYGIGKSKVAQIASYNKSPIFNSLVTTRWRDSAIGRPEDALIGVMYETFQVNSDIVIDDNAPDWLLEKTDLKQGDKLRGLLGYEVDRMFGNAPKNIVRVAHSPYPYGGGTRYADMTVYTADSGAKVFATGSMQWVWGLDDYNAPQLRSAFLNSGAQQITRNVLAKLLSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY17</accession>
    <name>A0A2G4EY17_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54411">
        <property type="protein sequence ID" value="PHX54411"/>
        <property type="gene ID" value="CP500_016340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="333" mass="35599" checksum="31E99E7463000B4F" modified="2018-01-31" version="1">MKAIVFETPGSPEVLRIQDIPAPTIQKETEVLVRLRAAGVNPIDTKLRSKGTFYPDLSPHVLGCDGAGVVETVGSGVQSFKVGDEVFFCNGGLGGPTGTYAELAVVDEKFLALKPASLSFVQAAAAPLVLITAWESLYDRGRLLAGQKVLIQAGAGGVGHVAIQLAKLQNADVCTTVSDEEKAKFVKELGADSVIFYKNADVVDEILTWTQGEGVDLAFDTVGGETFYQAIPAIKVYGDLVTILEPDPALGNLKAARMRNVRISLELMLTPMLQGLVNEQQQQARILQQCASLCDRNLLKIHVSQTFPLEEAQAAHELLEAGSVTGKIVLEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY62</accession>
    <name>A0A2G4EY62_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_016170</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54418">
        <property type="protein sequence ID" value="PHX54418"/>
        <property type="gene ID" value="CP500_016170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="177"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="424" mass="48119" checksum="BECF8B9AEB6D7461" modified="2018-01-31" version="1">MQKAERHIIKSTDARFDQLDNLAFQSKNLYNAANYVIRQNFLYGWGYLTYNRMASLMKSHPAYQALPAKVSQQILMILDKNWQAFFEANKAYKNEPTKFTGRPKLPKYKDKVKGRNLLVYTLQAISSKQLKKGIIQLSGTDISIKTTVRREGICQVRVVPKCDCYVIEVIYNEPESTRERDNSATVASIDLGLNNLVALTSNQPGFIPLLINGRPLKSINQFYNKRKSQLQSVLKGYLKTSSRIQRLTRCRHQKVDNYLHHTSRLIIDILSERQIGTLVIGKNRQWKNCINLGKQNNQNLVSIPHARLIQMLEYKAKLVGIEVVIQEESYTSVSNFLALDPIPVYGDSDAKRVEFTGKRIHRGLYKTASGLLINADVNGSYNIMRKALPNALSNGIGSCVVQPRRVNPLEVKVKGEGLHASHVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYB1</accession>
    <name>A0A2G4EYB1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribulose bisphosphate carboxylase large chain</fullName>
            <shortName evidence="11">RuBisCO large subunit</shortName>
            <ecNumber evidence="11">4.1.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">rbcL</name>
        <name evidence="11" type="synonym">cbbL</name>
        <name evidence="14" type="ORF">CP500_015700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>2 (2R)-3-phosphoglycerate + 2 H(+) = CO2 + D-ribulose 1,5-bisphosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:23124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="4.1.1.39"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-ribulose 1,5-bisphosphate + O2 = (2R)-3-phosphoglycerate + 2-phosphoglycolate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:36631"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58033"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterohexadecamer of 8 large chains and 8 small chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Carboxysome</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the RuBisCO large chain family. Type I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.39" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54509">
        <property type="protein sequence ID" value="PHX54509"/>
        <property type="gene ID" value="CP500_015700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016984">
        <property type="term" value="F:ribulose-bisphosphate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009853">
        <property type="term" value="P:photorespiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019253">
        <property type="term" value="P:reductive pentose-phosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08212">
        <property type="entry name" value="RuBisCO_large_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01338">
        <property type="entry name" value="RuBisCO_L_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033966">
        <property type="entry name" value="RuBisCO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020878">
        <property type="entry name" value="RuBisCo_large_chain_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000685">
        <property type="entry name" value="RuBisCO_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036376">
        <property type="entry name" value="RuBisCO_lsu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017443">
        <property type="entry name" value="RuBisCO_lsu_fd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036422">
        <property type="entry name" value="RuBisCO_lsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020888">
        <property type="entry name" value="RuBisCO_lsuI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42704">
        <property type="entry name" value="PTHR42704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00016">
        <property type="entry name" value="RuBisCO_large"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02788">
        <property type="entry name" value="RuBisCO_large_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00014">
        <property type="entry name" value="RuBisCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51649">
        <property type="entry name" value="SSF51649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54966">
        <property type="entry name" value="SSF54966"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00157">
        <property type="entry name" value="RUBISCO_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="2 11" id="KW-0113">Calvin cycle</keyword>
    <keyword evidence="8 11" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="9 11" id="KW-1282">Carboxysome</keyword>
    <keyword evidence="7 11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0601">Photorespiration</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RuBisCO_large_N" evidence="13">
        <location>
            <begin position="25"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="RuBisCO_large" evidence="12">
        <location>
            <begin position="155"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <feature type="binding site" description="in homodimeric partner" evidence="11">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="11">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="11">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="11">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX54509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="476" mass="53179" checksum="25A4CD0643D9A72C" modified="2018-01-31" version="1">MAYAQTQTQSKAGYKAGVQDYKLTYYTPDYTPKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDLLTDLDRYKGRCYDIEPVPGEDNQYICFIAYPLDLFEEGSVTNLLTSLVGNVFGFKALRALRLEDLRIPIAYLKTFQGPPHGITVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYEVLRGGLDFTKDDENINSQPFMRWRDRFLFVQEAIEKAQAETGEVKGHYLNVTAPTFEEMMERAEFAKEIKTPIIMHDYLTGGFTANTSLAKWCRKNGILLHIHRAMHAVIDRQKNHGIHFRVLAKCLRMSGGDHLHSGTVVGKLEGEKGITMGFVDLMREDHIEQDRARGIYFTQDWASMPGVMPVASGGIHIWHMPALVEIFGDDSCLQFGGGTLGHPWGNAPGATANRVALEACVQARNEGRNLMREGGDIIREACKWSPELAVACELWKEIKFEYEAMDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYK4</accession>
    <name>A0A2G4EYK4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TIGR03792 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000090">
        <property type="protein sequence ID" value="PHX54576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54576">
        <property type="protein sequence ID" value="PHX54576"/>
        <property type="gene ID" value="CP500_015295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022512">
        <property type="entry name" value="CHP03792"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03792">
        <property type="entry name" value="TIGR03792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="13128" checksum="6C3F2D7F1CFD34DE" modified="2018-01-31" version="1">MVIEWLKFKVPHEKWEAFIQRDEEVWTTGLRSFPGFLGKETWVDPVENEVVMLIRWQTRELWKSVPQSVIDELDAKMGDLQMPIAESREYQVRKFLPNNWVESPVLIGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYP4</accession>
    <name>A0A2G4EYP4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Circadian clock protein KaiA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_015015</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC hexamer phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer. Component of the kaiABC complex, at least composed of a kaiC homohexamer, a kaiB dimer and two kaiA dimers. The kaiABC complex also interacts with sasA.</text>
    </comment>
    <comment type="domain">
        <text evidence="3">The kaiA domain mediates the interaction with kaiC, the homodimerization, and is responsible for the clock oscillation function.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54644">
        <property type="protein sequence ID" value="PHX54644"/>
        <property type="gene ID" value="CP500_015015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011648">
        <property type="entry name" value="Circadian_clock_KaiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020844">
        <property type="entry name" value="Circadian_clock_KaiA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020856">
        <property type="entry name" value="Circadian_clock_protein_KaiA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017944">
        <property type="entry name" value="KaiA/RbsU_helical_domain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07688">
        <property type="entry name" value="KaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01247">
        <property type="entry name" value="KaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101215">
        <property type="entry name" value="SSF101215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51431">
        <property type="entry name" value="KAIA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51430">
        <property type="entry name" value="KAIA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0090">Biological rhythms</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KaiA N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="KaiA C-terminal" evidence="5">
        <location>
            <begin position="196"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00019845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="311" mass="35511" checksum="A879D81E974683DC" modified="2018-01-31" version="1">MLPQLSICIFVKSEELAASAINLLGGGRYALTQVKSAIEFFEYLKHNYHLDCLVFEVDGDLRSLTGKLQERSIFLPAVIFSTKPGDDDRPEQSSSSGFEARASTSQKIEEQSCSFFYHPAEVQLPIARSGEIVASIDRAITQFLKLSTPVPFDDQSANVCATAQLTAQSLLQRQQRRLAEKLRERLGYLGVYYKRNSQNFLRNLSPEEKTKFLEQLKSIYRKIVLNYFSEDTAVNNQIDEFVNLAFFADVPVTQVVEIHMELMDEFAKQLKLEGRSEEILLDYRLTLIDAIAHLCEMYRRSIPKETSEGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ17</accession>
    <name>A0A2G4EZ17_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pilus assembly protein PilO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54751">
        <property type="protein sequence ID" value="PHX54751"/>
        <property type="gene ID" value="CP500_014290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="267" mass="29037" checksum="4740A1D4C71EADAD" modified="2018-01-31" version="1">MTYSQVEEQVEESSGQELFGIKLTPQVQAIAIAVVGLGIAGGIGYQFVLPEIQKTAEIQQKISEAKTTQLSLQTQIKKKAEAEAKQEQAKQRRADVTAMFASDAGATTLLLDMTQLVNRINMGVEGDQGKAKLTKFEPDILPAPTAATAAPVDPDILKDTSFGASLAGKLRRKKYKVEFEGNFAQTRSFMRNLELMQSLLVVRNLKSELAEASQTIEVDFLKGKIVPVQQQQTKLKTAFDLHALLPLKQEEKLPSPSPSAGATPVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ30</accession>
    <name>A0A2G4EZ30_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54783">
        <property type="protein sequence ID" value="PHX54783"/>
        <property type="gene ID" value="CP500_014270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="180" mass="19933" checksum="32CF4B34243F09C6" modified="2018-01-31" version="1">MTQPVDLNEVRNRVLSNQQSGTDLPNSTDRSVFVDSEGNIILRPQPGTERQVSRVPLKTFAANLTADRQIVAQKLPNNTQEMFISGVTGWVYGIISELGDQYTMFAYSDGSLYQVMVLFPEVAGKFNQHDSHLFQDGRVCFGDAGGLPTLEQAYAKSVLWATGFSSYLRTGLFPFSINNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZP0</accession>
    <name>A0A2G4EZP0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54976">
        <property type="protein sequence ID" value="PHX54976"/>
        <property type="gene ID" value="CP500_013215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="22459" checksum="738BABBDC415EABE" modified="2018-01-31" version="1">MPYSKFTLSKAVDDFNLTIIEGSRFLPEIAPLTPSPLLRDTLRETIPWAIAVSSEKARSGGIINPVLLEVKRQLQGQISVFSGEEFNVEPEAELTGYVDFLLSRSPEQLFIKAPAVILVEAKKEDLKPALGQCLAEMVAAQRFNQQKQQPISTIYGTVTSGTVWRFLKLEEQCVSIDLTDYPLPPVEQILGFLVWMMTENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZQ4</accession>
    <name>A0A2G4EZQ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54991">
        <property type="protein sequence ID" value="PHX54991"/>
        <property type="gene ID" value="CP500_013290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="6991" checksum="BA982ABB94C5877B" modified="2018-01-31" version="1">MLFVICYLLTPCPMPNAQCPMPYALCPMPYALCPMPNSLCPIPYALYPMPNARFPIPHSQFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZT3</accession>
    <name>A0A2G4EZT3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2256 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55026">
        <property type="protein sequence ID" value="PHX55026"/>
        <property type="gene ID" value="CP500_012995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017136">
        <property type="entry name" value="UCP037205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37463">
        <property type="entry name" value="PTHR37463"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10013">
        <property type="entry name" value="DUF2256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037205">
        <property type="entry name" value="UCP037205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="51" mass="6210" checksum="F208BEFDB8E28DE6" modified="2018-01-31" version="1">MAKQISKSDLPTKMCPVCDRPFTWRKKWADCWDEVKYCSDRCRRRRNPTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZV0</accession>
    <name>A0A2G4EZV0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55029">
        <property type="protein sequence ID" value="PHX55029"/>
        <property type="gene ID" value="CP500_013010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030655">
        <property type="term" value="P:beta-lactam antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045155">
        <property type="entry name" value="Beta-lactam_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000871">
        <property type="entry name" value="Beta-lactam_class-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35333">
        <property type="entry name" value="PTHR35333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13354">
        <property type="entry name" value="Beta-lactamase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase2" evidence="2">
        <location>
            <begin position="301"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="545" mass="58183" checksum="86678E047E45A77E" modified="2018-01-31" version="1">MAERFPKRSILSVLSSISSTESGSEPPQSGKANQSSKSARRGSPKSQKPQPEVSTKATVPSTLPLQPLSTSRSRANSSASTNPPALNPPDFISNPQSAITGKKLGKSQTPQSKGRQSRKKDLAAIDLFDPGAYVENVSAIASNPNTQLIPPTTPTPRESPLQSPPSRIEDTETPPQVKKRPAPKPRPQASKKPRKRPASPSTPPLVYATRLLILGVGMAVICGTMLSVVNAVSRSGVSAQEQKTAIADGQKTQAESDSANATVANPPALQLNQELAALKTQVQALATENPTLTAGIFLVDLDSGSYLNFNGDTTFASASTIKVPILVAFFQAVDDGKVRLDQTLTLRAEDIVGGSGEMQDQAPGKKYSALEIARKMIVVSDNTATNMMIDLLGGAEVLNQHFATWGLRATVLNNKLPDLEGTNTTSPKDLINIIAQIDRGNLVSVKSRDRIFQIMQQTKNDSLLPKGLGAEAIIAHKTGNINTLLADAGMVDLPNGKRYLVAVMVKHPPETEKPAQSLIRDISRMSYRYLNDGEATVDSKVKIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0F5</accession>
    <name>A0A2G4F0F5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_011885</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55233">
        <property type="protein sequence ID" value="PHX55233"/>
        <property type="gene ID" value="CP500_011885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044665">
        <property type="entry name" value="E_coli_cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43246">
        <property type="entry name" value="PTHR43246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="3">
        <location>
            <begin position="22"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="444" mass="45674" checksum="8B60F5C082D40B7D" modified="2018-01-31" version="1">MAAALPLPGKATVVQVINGQPVTIEVDGTNAPITAGNFVDLVERGVYNGVMFHRVVRQPDPFVVQGGDPRSRDATIPASQLGTGNFIDPDTNQGRFIPLEIKPQGATQPVYNQLVTQTPQLQHTVGAVAMARSSALNSASSQFYFALRDLGFLDGNYAVFGYVTQGFSTVNAVQQGDRISSAKVVQGIVPSRVSSIISDVDLLNNFINTTNLVSLPLRSLKLGNTPNNYQVTSQDSQQNPSGVLGGSGGDRITGSPTNDAINGSQGNDTISGEIGDDFLRGGKGNDLISGGVGNDILTGNLGDDTLNGDAGNDFLRGGKGNDVLIGGDGNDILIGDAGNNTLTGGAGADTFVLITGQNLALDTTSNLILDFTPGEDRIGITGTLSSVAFTASGSNTLIQLGGATLATVQNAAPTAVQNAAFAINFSTISRPDDLPVGDAALRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0S7</accession>
    <name>A0A2G4F0S7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I-D CRISPR-associated protein Cas5/Csc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cas5d</name>
        <name evidence="1" type="ORF">CP500_011230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55363">
        <property type="protein sequence ID" value="PHX55363"/>
        <property type="gene ID" value="CP500_011230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017576">
        <property type="entry name" value="CRISPR-assoc_prot_Csc1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03159">
        <property type="entry name" value="cas_Csc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="258" mass="29070" checksum="AB729F7AD1C2CC7D" modified="2018-01-31" version="1">MTQNPSNSILTHSTAHLIELWCAEPVFFASRELSDTYYTEGAIGNYALAYALGWARSPYRLTGQDTSRPRYIEDLTPLSGNSYILPAWPADGTLSFRFERFNALSDSYWYAMTNNRVATAREDLPLSRTGKKPSTYRPSNFPQTGRLRVIERGNRFQTLVFGDRELPEYIRVGKFTSKVRVEIIKKLDVIQLPVGDYRCNTYLSATDLPANIELLAFDLISMPPASLLKNLSFRSEALKVGDFILPANLEFCGGNNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0V0</accession>
    <name>A0A2G4F0V0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55376">
        <property type="protein sequence ID" value="PHX55376"/>
        <property type="gene ID" value="CP500_011185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="171"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="387" mass="43462" checksum="D037388A388601D9" modified="2018-01-31" version="1">MKIIVEGWRSTYHSYSVANQFQMLEMLDRPEVELLHRDMPYIDPAWQTTTSLFDRPIERLLKSIPSPSPNQSADVTLRMYCPWNFAASTSAQTWVFAATEWGVITNLLLEAIGVNSITETPVNSQVKIITPSAWSKAGLIRSGVECDRITTVPLGADTDIYYPPSDQQRQTLRKTFGWEDYFIFLNIGGQTDRKGIRPLLKAFAAVVDKYPHARLVLKGSELFYPSRDEIVKASRVVLNDAERAKVSPRLIYTNHQLSFTQIAQLYQAADAYVSPYLAEGFNLPVLEAAACGLPVICTAGGPTDDFTHPDFALPIESKFRTLNFEGENIFILAPEWEHLTQLMQTVIEQPAFTTKARLAGPHFVSENFTWKHAVDKLLDVISISVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0V1</accession>
    <name>A0A2G4F0V1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetate kinase</fullName>
            <ecNumber evidence="6">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ackA</name>
        <name evidence="8" type="ORF">CP500_010980</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55390">
        <property type="protein sequence ID" value="PHX55390"/>
        <property type="gene ID" value="CP500_010980"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="214"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="289"/>
            <end position="291"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="337"/>
            <end position="341"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="402" mass="44084" checksum="AFAA6EA11954FBF2" modified="2018-01-31" version="1">MKILVLNAGSSSQKSCLYELNDTQPDRPLQPLWEAKIDWTHQQGVSELKVKTAKGTQFEEEFASESRTDTISRMLETLWKGETQTINDLNEIDIVGHRVVHGGQDYQESTLISPDVKKAIARLAVFAPVHNPVNLEGIEAIENLLPNVPQIAVFDTAFHAQLPPAAFVYPGPYEWLENGIRRYGFHGISHQYCARRAAEMLNRNLADLRLISCHLGNGCSLAAIRGGVSIDTTMGFTPLEGLMMGSRSGSIDPGIIIHLLRRSDITAEKLDNILNQNSGLKGISGVSGDMRQIGEAISQGNERAQLALDIYIHRLRAGIGAMLASLGGLDALIFTAGVGENSAFVRATACEAFGFMGLKLDGEKNQQVQGDEDIATADSAVRVLVIHTQEDWEIARECWKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0X3</accession>
    <name>A0A2G4F0X3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55412">
        <property type="protein sequence ID" value="PHX55412"/>
        <property type="gene ID" value="CP500_011110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="632" mass="70616" checksum="5B3761D742F6BEED" modified="2018-01-31" version="1">MTVAARQSRAQILELDLQKHLQSAGFKNLPLYLSCDFREASLTVVGEHPRSLVLKAQQTFAVLEAAILELQPESIQQIGLCLKNTGQKQPYAFHSFTMNHPVLSRKRTVEVRKKTEEIPAEATESAIALNPPDTTNIPDAATDLPLETDATDPGVEETFPDVWETPNNAEPIAFQVSSIPTDHAQNPFDPLDLEPVTVTKKTKHSPFVSLAVVVISSMAIVVLGGVYHLLSRPCVIGECTPLADAQQLSDDSATTLKTSKVDNTPEAAQEQLKQAIALLEPIPFWSIHHSKAQDDIDRYRRQNQNLNFAVDAARLAVSAAETTENPPHSAQNWQEAQSLWQSAIAKLKEIPQNSTAYPFAQQKLKEYRTKLASGNRQLTTEMKAEKKLRSAKNTAQVAEARAIVAQKPESWDKVEANLQKSLDTLSEIPTNTESYQQAKVLVPKYESKLSQARDRKTLEGTAEKAYTQAVTIAAQARIFEERNAWFEASQHWRRALSYAEKVPSTTDYYLKTKSLMPSYRTYLHEAEVKLEEERNMQKARTDLDKTCKGNPKICDFTVSKDLIAVQMTPDYVQKLQQTFIQAENTNATKTRQAVEKHVQTLQKALEAIGDNAKIPMQVYDSEGKRIATQTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Y6</accession>
    <name>A0A2G4F0Y6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Non-ribosomal peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_012455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000064">
        <property type="protein sequence ID" value="PHX55117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55117">
        <property type="protein sequence ID" value="PHX55117"/>
        <property type="gene ID" value="CP500_012455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1014"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1360" mass="150228" checksum="A1054F65D86CC1D6" modified="2018-01-31" version="1">MKITAALQPKLTAVDFDPFADGELFACVPATESQKEIWIAVQMGDEANCAYNESMCLRLQGNLDVESLRFSIQELVQRHEALRATFSPDGSTLCIASSIEIDIPAIDLSILGDRDRESKLAHLRRQEVELPFNLVRGPLFRSQIIKLQEQEHIVILTGHHIICDGWSWGILFPDLGAIYAARHQGLAANLPQPESFIEYAILQEEQATSPEVIDAEKYWLKQFSGTIPVLDLPTDRARPALRTYNGSREDWELNPDLVTNLKRLGKKAGCSFFTTLFAGFEAFMYRLCGQEDLVVGMPAAGQLVGGKDKLAGHCVSLLPLRTRIDGEQSFIDYLRSRRTAILDALDCQQLTFGTLVKKLALPRDFSRIPLVPVTFNLDVQLAQEQLNFDGFQAEVFSNPRTCENFEWAVNASETKTKLVLECQYNTNLFDAATIRRRMAEFEALLEGIVANPQCPLKNLPVLTAAERQQLLVEWNSTQTNYPDSACIHQLFEVQAEQTPDAVALVLGEQQLTYQQLNCRANQLAKYLQTLGAGPEVLVGVCFDRSLDAIVSLLAVLKAGSAYLPLDPAYPKERLDFMLSDAQISVLLTQHNLVERLPDSGAKVVCLEVAREEIDAQSEENPANLANAENLAYVMYTSGSTGKPKGVCVVHRGVVRLVKDTNYASLTAAEVFLQLAPISFDASTLEIWGALLNGAKLAVFPAGSPSLAELGEAIRLYNVTILWLTAGLFHLMVDDRIEDLKGVRQLLAGGDVLSVPHVQKLLREVPNCQLINGYGPTENTTFTCCFAIDSASEISNSVPIGRAIANTQVYILDRHLQPVPIGVPGELYAGGAGLARGYLNRPDLTAERFIPNPFTNKEDGLENAKNRSVSSLLPASNRLYKTGDLARYLPDGNIEYLGRTDNQVKIRGFRIEIAEIEAVIAGHPDVSQVAIAVQLDASGNKCLAAYVVKSPGQILAAGILRSFLQERLPDYMIPAGFVFLEALPLNPNGKVDRRALASQKWQSSSAAPNEIIAVSPRDKFEFQVTEIWEKVLGINSIGIRDNFFEVGGHSLLGARLLAEIEKVFDKKLPLSAIFQSPTVEQLANILRDTEWSSPSPSMVVIQPGTGSYKPPLFCIHVLGRGLEFYRPLMNYLDRSQPVLGLSTQIMDEKLAPPNRVEELATYYIKEMQTFQPQGPYFLLGVSFGGTVAFEMARQLDAKGEKVALLGLLDTYGPAAFKNLPEIKPGQQLTKILQLEPAVFLEKAKMNLGGRIEKLTHCYWRNLSKVYRAIGRPVPIFLENFTHGELNNQALRHYVGGVYPGRATLFKAVETAILFGADLELGWGEVITGGIEIYEIPSDHLGMLKEPHVRVLGEKLQACIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Y8</accession>
    <name>A0A2G4F0Y8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Iron export ABC transporter permease subunit FetB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_011130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0014 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55416">
        <property type="protein sequence ID" value="PHX55416"/>
        <property type="gene ID" value="CP500_011130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005226">
        <property type="entry name" value="UPF0014_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30028">
        <property type="entry name" value="PTHR30028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03649">
        <property type="entry name" value="UPF0014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00245">
        <property type="entry name" value="TIGR00245"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="259" mass="27613" checksum="5EEE447E1531AFE1" modified="2018-01-31" version="1">MLILLDFTDLGWALGMVAIAIGLSAWQGLGLEGSIAIAAGRTLIQLILVGYVLAVIFDPEAKNPWLVLAVLAIMVTTASVVASNRISKKIKNLLPLVSGAILISTALTLAYTSLLILQPEPWYEPQYLIPLAGMILGNAMNASAIAGERLVSTINSSQLEIETHLSLGSTPQQAVKQYRKDAIKAGLIPTLNTMTVVGIVTLPGMMTGQMLSGVAPLDAASYQILIMFVLALATLIATLLLTEGLCRKFFNQDAQLIKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Z0</accession>
    <name>A0A2G4F0Z0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55415">
        <property type="protein sequence ID" value="PHX55415"/>
        <property type="gene ID" value="CP500_011125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="213" mass="24232" checksum="1D943B116272C335" modified="2018-01-31" version="1">MIQIATKTLTFEEFAEWKPENGRYELHNGEIVEMSQPIGDHEEVIGFSARKLTVEFDRLNLPYIIPGQALVKPPENESAYSPDILILNRRNLASEPLWKKFSTVTQGASIPLVVEVVSTNWQDDYIKKVGEYELIGIPEYWIVDYLGLGGRRFIGNPKQPTISIYRLIDGEYEISQFRGDDRIESPTFPELNLTVQQVFQAGLIADEIPGDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F191</accession>
    <name>A0A2G4F191_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55508">
        <property type="protein sequence ID" value="PHX55508"/>
        <property type="gene ID" value="CP500_010400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="414" mass="43293" checksum="5C73ECED0C61A863" modified="2018-01-31" version="1">MSKRSSVESSNHQSSSTPINHALQAALGCLDVNLEAELTTYRRHRRRAEQWVSPSLRPDKQTANANQLGQNLPTAVEESQHSLSPLSLGGSRGGTAITATADERQPIKLSISAAPPNNYLESSEKLIESLDSPTAEAPEERSLAASLLTPLGLCSMLLFLVSCTALGYAVFYPSSLAKMVGLNRLVDRKAPSQSQNNASTVADTGSKELPKAPNLASKEFVELDLSTLSNVKPTASPIASPSPKASIPPTPAPVTNPSGAVPIPTEDGNSSTVRERGLNNLSKALLPSPSPSAAQTVPTLPTLPPTPSPLAANSATPAAASPDVASPVPAVGANGHSPLLGTPKRATDGFYYVVVDYSDAKSLEQARIAVPDAYVRKFSKGVKIQMGALNDAASAELLAKELQAKGVKPQYYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1A9</accession>
    <name>A0A2G4F1A9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55551">
        <property type="protein sequence ID" value="PHX55551"/>
        <property type="gene ID" value="CP500_010215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="12320" checksum="F9EDC721FE6A7365" modified="2018-01-31" version="1">MKINDKLKTILTQLRSQFEQLYGDRLTQMVLYGSQARGDADPDSDIDVLVVLKGQVNPGEEIKRISHIRADLSLQNDEVISCLFMDENRFVNYNGPLLRNIRKEGIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1C9</accession>
    <name>A0A2G4F1C9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55571">
        <property type="protein sequence ID" value="PHX55571"/>
        <property type="gene ID" value="CP500_010090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="13421" checksum="8394E32A48C043DE" modified="2018-01-31" version="1">MATITFQIPDELALRLDPLKDELPQILMLGLREVEANPSNGFSGLTQILEFIASLPSPEEILALRLSDVLQAEIDTLLEKNRTEGLTPIEQRLWQQYEFVEHLVRIAKAQALLKLSEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1D6</accession>
    <name>A0A2G4F1D6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55548">
        <property type="protein sequence ID" value="PHX55548"/>
        <property type="gene ID" value="CP500_010200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="698"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1027" mass="115818" checksum="01E52578AA0FC815" modified="2018-01-31" version="1">MNEARREAYLNLIQSLLNCPSGEINQTLQANSELVDAGLVQVMQVVAENERAEGNENAADFLTSLAIYIVEVVESPSANSQLEFLLQVLRVTAESGGDHNVIHPLLRDNLNLINDNFAVFLRNWVREALPNLDSQEQISLIAIVATFSDVIGQFPLGSRASNLEIAIAGYEIALNVYTRQEYAEYWAQTQHNLGNSYSDRIRGEKAENLEIAITAFLAALSVYARKAFSFEWAMTQNSLGLTYRDRIKGEKAHNLEMAIAAYREALLVLTPKAFPVEWAMTQNNVGLAYFDRIRGEKAHNLEMAIAAYQEALSVDTRKAFPQHWAITQNNLGLAYTARIRGEKADNLEMAIAVFQASLAVINRKAFPQDWAMTQNSLAGAYRHRIRGEKADNLEKAISAYRAALSVRTREAFPQGWADSQNDLGNAYGDRIRGEKAENLEMAISAYRAALSVRTRKAFPEDWAMTQNNLGLAYINRIRGETADNLEMAISAVQAALSVYTREAFPINHAQTLYNLGRAYGLNSQLPEAYNTLNTAINTVESMRSEIIIGGEADRQKLAEEYNKIYQVMVEVCVVMENKTAALEYIERTKTRNLVELFHNARSLPQNVQRISFQEIRSLLGEDEAILEWYISQKSLKVFIITRNSTQPDVWESSLEDLQALEKFQQEYIDDYINHPDNWRNQLETRLEKLAKILHIDKIISHLPKKCQRLILVPFRYLHLLPLHALTSRRLRQNVEETGTLLELFPGGVRYTPSCQLLQLSQRVNPTGEESSPTRLFAIQNPTEDLDFTDIEVEAIAKSFNPAEVLIREKASKTGLQQQLKALQNADIAHFSCHGFFYFLDPRKSALILAGAKIATDNVDSDNKSYIRLSEDELLDIEKCLTLEEIFDLPLSKCSLVTLSACETGLTDIGDTTDEYIGLPSGFLYAGTTNVISTLWAVNDVSTAILMIRFYELFLSETRPPVAIALRESQLWLRDATVQDLVDWVAGCKLISDERKEEMQNSIEFGKKPADKRYQSPHFWAAFCAIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1H6</accession>
    <name>A0A2G4F1H6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system HigB family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55613">
        <property type="protein sequence ID" value="PHX55613"/>
        <property type="gene ID" value="CP500_009785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018669">
        <property type="entry name" value="Toxin_HigB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09907">
        <property type="entry name" value="HigB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="12425" checksum="585B673AACEC6DF4" modified="2018-01-31" version="1">MRVISRKPLREFWEKHPNAEPSLLIWYQRTSQAEWQNFVEVRQVFPSADLVGNFTVFNIGGNNYRLICFIDYEYQKVFVRSVLIHSEYDKENWKNDDWFENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1I5</accession>
    <name>A0A2G4F1I5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rpmG</name>
        <name evidence="4" type="synonym">rpl33</name>
        <name evidence="5" type="ORF">CP500_011320</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55327">
        <property type="protein sequence ID" value="PHX55327"/>
        <property type="gene ID" value="CP500_011320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_L33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168">
        <property type="entry name" value="PTHR43168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7193" checksum="6D5C334F72C89569" modified="2018-01-31" version="1">MAKGVRIIITLECTECRTNASKRSKGVSRYTTTKNRRNTTARLELKKFCSHCNKHTNHKEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1V9</accession>
    <name>A0A2G4F1V9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1825 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55725">
        <property type="protein sequence ID" value="PHX55725"/>
        <property type="gene ID" value="CP500_009505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014954">
        <property type="entry name" value="DUF1825"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08855">
        <property type="entry name" value="DUF1825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="12756" checksum="E9A171633DFDDF23" modified="2018-01-31" version="1">MGFFDSEIVQQEAKLLFEDYQSLTKLGGSYGKFDREGKKMFIAQMEAMMDRYRIFMKRFELSEDFMAQMTVEQLKTQLNQFGITPQQMFEQMNSTLERMKSELEKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F241</accession>
    <name>A0A2G4F241_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polysaccharide/polyol phosphate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_008645</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55816">
        <property type="protein sequence ID" value="PHX55816"/>
        <property type="gene ID" value="CP500_008645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10147">
        <property type="entry name" value="Wzt_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029439">
        <property type="entry name" value="Wzt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14524">
        <property type="entry name" value="Wzt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="25"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="62"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="690" mass="78569" checksum="B262569A5AF98750" modified="2018-01-31" version="1">MRQAIVVKGLGKRFNRYSADRPFTIMEAALWGWWRMKPQAHFWALRDISFSVSPGEMLGILGKNGAGKSTLLQLVGGIGRAEEGTIQVNGKIGGLLDLGAGFHSDLTGRENVFVGAVVAGLTRREAAHRFDDIVEFAELEQFIDSPMRTYSTGMQMRLAFSVAIHTDPEVLLVDEHLSVGDVAFQAKCLNKITEFKTKGCAIVLISHNAGQIQKLCDRALWLREGKIMAYGEPEVVAGQYLSEMRSSTEKRTPMRPPEVASTGSELRVNENRFGSLEVEITDVKVLPDEEIDSGDSVTIEIHYSVPKQIPAAIFGVTISREDGQNCFDTNTNQMGRLVPLAKGEGKIRLHLDRLDLGNGQYYVNAGVYEKSWAYAYDYHWHVYPLYVRSTVHQKTILCPPYRWEFQGKMEVLDIPKKPETTHALNKNNPGYAKISTQLKNKQKPDFLILGAQKCGAEALCGYLENHLQIIKEGARRVQFFDLNFERGVEWYNKQLTRSVAGEKVLLWEMTGYYIYHPLVAERVYKCFPDVKLIVMLRNPVKRAWLHYNLEVAIGCEKLEFEKAIASEGDRLKGEIEKIRSDDGYYSFNHQHYSYLSRGIYVEQIKNWLDYFPREQLLILKSEDFQANPGKEFAKVLNFLDISGSTVKEYEVNSAEDYSKMPEAIEQELTSYFEPYNQELSELLKEDFTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F295</accession>
    <name>A0A2G4F295_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromophore lyase CpcT/CpeT</fullName>
            <ecNumber evidence="3">4.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cpcT</name>
        <name evidence="4" type="ORF">CP500_008540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CpcT/CpeT biliprotein lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.-.-.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55869">
        <property type="protein sequence ID" value="PHX55869"/>
        <property type="gene ID" value="CP500_008540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017009">
        <property type="term" value="P:protein-phycocyanobilin linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16338">
        <property type="entry name" value="CpcT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01460">
        <property type="entry name" value="Chrphore_lyase_CpxT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010404">
        <property type="entry name" value="CpcT/CpeT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038672">
        <property type="entry name" value="CpcT/CpeT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35137">
        <property type="entry name" value="PTHR35137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06206">
        <property type="entry name" value="CpeT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="199" mass="23100" checksum="51893E1515AE683A" modified="2018-01-31" version="1">MNSVKSNDLITLAQWMAGDFSNYKQSYDKPQQFAHIHILFRPLPFEFFNAIGFYSEQVYDHDLWTPYRQGVHKLIDQDSQIYIENYSLNDPVQYAGAARELSILKTIKPDCIQRRYNCSMVFERDGEMFRGSVEPGNQCLIEKRGCSTYLISDVEITETTWGSLDRGMDVNTHQQIWGSDNGSLWFEKRQSFAAEVPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2C3</accession>
    <name>A0A2G4F2C3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55910">
        <property type="protein sequence ID" value="PHX55910"/>
        <property type="gene ID" value="CP500_008010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="6985" checksum="40EEBF757D7D4113" modified="2018-01-31" version="1">MSEINKPVFQINQQLFQQLTEWQEKIAQEDELASESEDEKPTEVKNPIASHEEHSQTDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2C6</accession>
    <name>A0A2G4F2C6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_008085</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55924">
        <property type="protein sequence ID" value="PHX55924"/>
        <property type="gene ID" value="CP500_008085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="5">
        <location>
            <begin position="30"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="420" mass="46335" checksum="1B1C7E57FCCF5893" modified="2018-01-31" version="1">MTLIQEKTLASKVRGDFPILTQKVNGKPLVYLDNAATSQKPLAVINAWREYYEQYNSNVHRGAHTLSGKATDAYEGARDKVAAFINAASRQEIVYTRNATEAINLVAYSWGLNNLQAGDEIILSVMEHHSNLVPWQMIAQKTGAVLKFVELTETQEFDLEQFKTLISEKTKLVSIVHVSNTLGCINPVQEICKIAHRFGAKVLIDACQSVPHMVIDVQAMDCDWLVASGHKMCAPTGIGFLYGKLDLLREMPPFFGGGEMIADVFLDYSTYADLPHKFEAGTPAIGEAIALGAAIDYLSNIGMDQIHACEAELTAYLFQQLRQIPEIKIYGPQPDSNGEGRAALAAFSAGEIHPQDLATMLDEEGVAIRSGHHCTQALHRYLNLSSTARASLYFYNTREEIDVFVKALKETIAFFGQIMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2E1</accession>
    <name>A0A2G4F2E1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13 14">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="5 13 14">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">murD</name>
        <name evidence="17" type="ORF">CP500_008020</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="5 13 14"/>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55912">
        <property type="protein sequence ID" value="PHX55912"/>
        <property type="gene ID" value="CP500_008020"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 13 14" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 13 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="12 13 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="16">
        <location>
            <begin position="108"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="15">
        <location>
            <begin position="305"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="110"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX55912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="449" mass="48493" checksum="BC695988C67166B1" modified="2018-01-31" version="1">MPIAHIIGLGKSGISAARLLKREGWEVTLSDRSSSPNLLEQQQKLATEGIKVELGKSFEPTESIQLVVVSPGVPWDIPALVTARKLGIETIGEMELAWRYLKSPWVGITGTNGKTTTTALIAAIFAEAGLYAPACGNIGYAACELALAEKQPDWVIAEISSYQIESSPSVAPRIGILTTLTPDHLSRHKTLENYYSIKAQLLKNSQLQVINGDDPCLRQQGLDNWPDACWTSIKGEKELLGNADFGAYIQDGWVIAQSEKILPADALRMVGEHNLQNLLMAVAAANLAGIDKSAIAQAIAKFPGVAHRLEHIRTWEGIDFINDSKATNYDAAQVGLASVSAPAILIAGGAPKEGEDGAWIDTIKAKAAAVLLIGDAAGIFRDRLEKANYNTWEIVETMEKAVPRAAELAKQNNAKVVLLSPACASFDQYQNFEQRGDHFRQLCLETVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2H3</accession>
    <name>A0A2G4F2H3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_008230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55949">
        <property type="protein sequence ID" value="PHX55949"/>
        <property type="gene ID" value="CP500_008230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="64"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="256" mass="27452" checksum="8BC6B748469EC0C6" modified="2018-01-31" version="1">MDNLEKFARSKTASIVMPIAATILLFLVWETLVFLFKIPPYNLPAPSAILAATFNQSQALIENSGQTLFTTLAGFILAIIAGVVLGFAIGYSRIAYIVLYPLLVGFNTVPKVALVPLFALWFGIGTVPAILTAFLLAFFPIAVNVALGLDTVEPEMKDVMRSLGASQIEIFQKVGFPHTLPYVFASLKVAISLAFVGAVISETVASNKGLGYLIVTASSNFDVPLGFAGLMVLAVMGTVLYGLFAAAEKYLIYWAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2U6</accession>
    <name>A0A2G4F2U6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2079 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56076">
        <property type="protein sequence ID" value="PHX56076"/>
        <property type="gene ID" value="CP500_007140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018650">
        <property type="entry name" value="STSV1_Orf64"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09852">
        <property type="entry name" value="DUF2079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="562" mass="63926" checksum="3B773165E31D1B20" modified="2018-01-31" version="1">MIFLSGKQNSSLNEVMKVAAVFFVLCLLLTLHRYYSFYATYDQGIFNQLFWNGTHGHLFESSLSSALSTNVVHQNQIPEVFYYRLGQHFTPALMLWLPIYSLFPSPVTLTVLQVTLITAAGLVLYPLARHYLEPRLSAAIVVSYYCANAVIGPTLGNFHDVCQTPLFVFSLLLAMEKRWWPLFGILATLILAVREDGGIVLFGVGVYLILSRRYPLTGLAVCILSFGYMIVLTNLIMPLFSDDISQRFMMERFGQYADGEEASTLEIIWGMVSNPGRLVEQLFTPFFGKIKYLLGQWLPLALVPAVAPASWTIAGFPLLKLFLAKGESVLAINIRYAMTVVPGLFYGAILWWADRQKEEDKIRSGEKTVLRFPSAMFPFPSSAKFRRFWSFCICLSLFFTFTSNPNRTFSFILPDAIDPWVQVPLIRQWQHVSQVRPLLAEIPTDASVSATNTIVPILSSRREILRFPMLELRNDARETVKMEYVIADMWQLQQYQTAFRRERGQLRAIVPQIDRLSNSGEYGIIGFEDGAILMRKDAASDSLSVAAWTRFRRELEPILNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2V2</accession>
    <name>A0A2G4F2V2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_007295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56103">
        <property type="protein sequence ID" value="PHX56103"/>
        <property type="gene ID" value="CP500_007295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="804"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="846"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="887"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="981"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1022"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1076"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="684"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1145" mass="128894" checksum="49DD8BBCA970FA0A" modified="2018-01-31" version="1">MARYALVIGITEYQSSQMSRLPKAASDAEILAQVLEQYGGFEVKRLPARWNAEKNCFEISGNKTVTAAEVGQELRTLLLDRATKNEALIYFAGHGFTFCDTLGQQKGVLATSDCQVEMAGKEVIDYKYGISLASLNDLIQQSDLSSLVMLLDCCHSGYFLESQLVQQTLGAFSTQRDYYLMAACRTFETAKSLKGEPNSYFTGAVLKGLASANAGRNRRVSGDLLFDYISGELKSFVQEPIRMGWGRSITLVTYPQSEMPATEISFDRQNPYLGLSAFEAKQEKYFCGREEAVRMLITHLTNSRFIPVIGYSGSGKSSLIKAGLLPELSRDRIPGSSHWPVESFTPGKHPLGKLVDILARYRDQNQLFVIFIDQFEEVFTLCEDESERGSFIRLIAEEMNDSERKSRMIIALRGDFLIRCADYSDVLNLINHIPPRTYIVKSLGMEELPDAIEKPAQLHGVNFERGLVSQIAQDVAGQPGALPLLQYALKELWRVCIEKPEFPEPLLTRKGYEDIGGVQGALENRANVIYQSLSEADRLFVRQLFMELVQLGEGSEVTRRRVDWDRLRAIADSAEQLDRVIGLLAGAQQRLIIVDENTVEVAHEALLCRWKLVSNWIEEDLENIRICRRLEIACREWEETYGKSDEALLTGARLAEVEEWERRVLPNLTGDEREFLVKSVGRRDREIQDEIKILEREIQLTDEKYRAQKQRTRLAIVSGILLTFTLGLGLLTNVVVGQKREQEVSKVGILIGKAQQLLESNLQLDALIASVEALNEMKKQGRENPKELQKIQSVIFNVQERNQLKAHPGGVYGVSFSPDGTMIASGGVDKKIIIWNQVGKMLFSPSEGHKETIWSVRFSPNSQFVASASIDDTIKIWSKKGELIQILKGHKGNVYDVSFSKNSDRIYSSSRDGNIIIWDVKTGRSLETFKNPNSLNKSEYDILGLDLEPLKNHVVVYTGNKDYELTLWDLKNKSNKGIKTIGKTQSLIMSVRFNKNGNMIISCDNKGNIKIWDITGKLIGLINSHKDITLYAEFSYDSKYIASASLDKTIKIWNVDEVLNIWKNSQRGVAQPLTILAGHTSTVNRVSFNPLNSQSIASASSDGTVIIWEIPRKGMELDKRYKLDELLTKSCNFLSTYSNICQNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Z3</accession>
    <name>A0A2G4F2Z3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56133">
        <property type="protein sequence ID" value="PHX56133"/>
        <property type="gene ID" value="CP500_007025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="201"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="557" mass="62353" checksum="F1B25912720FF679" modified="2018-01-31" version="1">MDITAAVLYNKDGYDTGGKRLLGRHSAGEGFLKSLVQHGTADYLYCCADSEATFQEFCSRIQPWLSQPRKVRWIQADRPDLLSQPGTIYRPDPALADMVWARRFVDQRAYSVCGVTHTIATKYVMDAIGNLVTAPVQPWDALICTSAAVKTTVEQVMTAWGEYLSQRTGGKSKILVKLPIIPLGVDCSAFPQGLEALNLRRQQRQELDISPDDIVVLFVGRLTFSAKAHPVPMYIALERAAQQTKTKIHLIQAGWIEDPREESDFKHSAQIFCPSVNTIFLDGRKPEIRVNIWSAADIFISLSDNIQETFGLTPIEAMANGLPAIVSDWNGYKESVRHEIDGFRIPTLIPPPESCLDLALNYLDGSLNWPTYMGQTSVATAVDIDACTRALSQLIADSELRKRMGENGRQRVKEIYDWKVVIAAYEELWRELAEIRVSAPESVPLKAGMPPCPLSDDPFRVLSHYSTRTLSNEMMLSLGGIATPELLKQLQTIWFTSFGQDRRISVSIQMEILDTIKQEGAVSVGEVIKLYAKNDRELAYLYRTLLYLVKFDILVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F306</accession>
    <name>A0A2G4F306_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PEP-CTERM sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55847">
        <property type="protein sequence ID" value="PHX55847"/>
        <property type="gene ID" value="CP500_008775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013881975" evidence="1">
        <location>
            <begin position="29"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="294" mass="30983" checksum="D28735C0A1320C86" modified="2018-01-31" version="1">MLSPHRIVALTATFTAAAFSLLTAPAMAFVVGATNNTETLKNQLLGNQTAGLSNFSVSLTGNSAAFGTFGNDPFGLQSGVVLSTGIVANIPGENIKDNLMINGSDLNTDFGPQGEAGDLTQLDLSFFADSTAEKLFFEYVFGSEEFPEFGGSEFNDSFELLLNGQNLAKLSDDKTVTINNLVPNADNRSTDHPDYINNPTVTGLAASIIKLDGFTKVLGFEGLLKQNQTNVLSIRIKDVGDGNLDSAVFIKGGSVGTVPVEPVPEPMTMAGLIAGGAMLAAGRKLRDKHTTRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F327</accession>
    <name>A0A2G4F327_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Photosystem I reaction center subunit XII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_008525</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cellular thylakoid membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the phycobilisome linker protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55867">
        <property type="protein sequence ID" value="PHX55867"/>
        <property type="gene ID" value="CP500_008525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008213">
        <property type="entry name" value="CpcD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001297">
        <property type="entry name" value="PBS_linker_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038255">
        <property type="entry name" value="PBS_linker_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016470">
        <property type="entry name" value="Phycobilisome"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01383">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00427">
        <property type="entry name" value="PBS_linker_poly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005898">
        <property type="entry name" value="Phycobilisome_CpeC/CpcI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01094">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51441">
        <property type="entry name" value="CPCD_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51445">
        <property type="entry name" value="PBS_LINKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <feature type="domain" description="PBS-linker" evidence="8">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="CpcD-like" evidence="7">
        <location>
            <begin position="206"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="256" mass="28216" checksum="E6AC5B785D88A284" modified="2018-01-31" version="1">MSTLAATFVSEPVELRSNATEEDLQVVIRAAYRQVLGNVHLMESQRLTSAESLLRNSDITVREFVRQVAKSDLYQSLFFNTNSAYRFIELNCKHLLGRAPLEQTEISEHVQTYNGQGYEAEIDSYIDSDDYTQNFGENVVPYPRSIRSQTGIKNVGFNRMVSLLGGGAATSDSSNKPQLIATVANNLPQKIKLPSVGSSGAFSNTGKRFRITATKSGGAKVRMGNMNYEVSYAQLSQNIQNIQKTGGKILSINEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F384</accession>
    <name>A0A2G4F384_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56195">
        <property type="protein sequence ID" value="PHX56195"/>
        <property type="gene ID" value="CP500_006715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="427"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1018" mass="118111" checksum="1DA8AFD80E5379D8" modified="2018-01-31" version="1">MTEPQPIYRHFHPLVADAYTAVHQWLETKVQDANGYKLLPYNNLKQKLQETDWKHIAFQYYALFPTHYFKAAHSLEFILKEEQLISWLRHKQKVCILDIGCGAGAASTAFLETVIRLKEQGKLTNEVNIILIGVDPSHRAIGLYIQMMTNLKSASSHLINLEFKPVNQGFPNAINRINTYLRNELSSSDFPSLSNVLVMQVNVISPFSQIYRNSQANFEELRVLGIDIDGHTTENNLGLGTSEAQAYKQLIESVPIDFMHILTIGTKNMEKQVQIGTNSEITLDERIKEMVNTLHQLVGNRHSVHQISSGNHFVYFNNPQNCHWRDKSIIQYYAKFYADFMSICSADLAEDKDWNGVIGLDNLRLAWARAHNNLLRQALYDETEMRLFERDIEVKLYDLHEQLNAYYDDVALTNDLISYKVPKNEKGIRPKGLSRIEEEILSVAIIQKLGDKTSKLRGSSYAYKISTKHNSRDTEYLYEYWFEAYCYYMKKARDSASNYPNGAILRVDIESFYTKIIQDQLCAELSRELTVSERVRWLIRLLLSKNIDEHELGQGITQGSIGSGFYANIYLTSVDAKFGSGNEWGVEFHRYVDDMIIIIPNPEDMDVIESILTDELQKLGLNLNDKKTEKIYEVSSFLEQCNDDELLDKLNERFDSVVNPLWILNSEHRAIFSSSYHNDELWWHNIERYQQCLRAIRIYTHKTDLSRKIYKYLFNKKTRDRDLSKQKQFLGLEGELKSTQPPEEDSFTAINQWAASFRSSNNIWDNHRDELRRDLVKLFQDSWQSLHESDGSNSNEIRKLERYIRFALYRLSILGLEDIRGVLMEILRKEFWIIREPINVLENLARQGYLAEIRSLLVSYQNLKQSAEYLKAITIRAMRFLPNIDAQEWELIVEFATISNGSVSIAERLMATETWLCLGHKYNDFKQSHHIEAVKTALRFEPRPPSRLEKNYLLILGQFEPNAVQEFSVNVNDPMLVSARNLALEGNPSDIFDLPELKILREKYYSGQGPTDSEEGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3B3</accession>
    <name>A0A2G4F3B3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56225">
        <property type="protein sequence ID" value="PHX56225"/>
        <property type="gene ID" value="CP500_006580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="15264" checksum="89F231DA8946C121" modified="2018-01-31" version="1">MHLGLQIVRNAPKAIWIKSQNLLLHTLQLILETGFLEGVNYISACPTTETRFLDISPDYFRIKRSHSIMNSNNSLATTAVGGALVAGKLATLTGATATGIATTTGGIGISTVATATGTAMSVAIAPAIAIAAPVVAVGAFIWWLSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3S0</accession>
    <name>A0A2G4F3S0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56127">
        <property type="protein sequence ID" value="PHX56127"/>
        <property type="gene ID" value="CP500_006985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007434">
        <property type="entry name" value="FemAB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04339">
        <property type="entry name" value="FemAB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="398" mass="46461" checksum="BBA97D8BF2E50C23" modified="2018-01-31" version="1">MLKQPKSQYSVAWISKLADIPQASWDALAMPLKTPFLEWDWLNNLETSGSATGKNGWLPHHLTVWRDKQLIACAPLYVKSHSYGEFVFDNQWADLAQRLGIEYYPKLMGMTPFTPAEGYRFLIAPGEDEDELTGIMVSAIDHFCDRHNISGCNFLYVDPVWRDRMERHGFSAWLHHSYIWQNQSYQNFDNYLGTFNANQRRNIKRERKAVEAAGLLVKTLTGDDIPQAMFGQMYAFYENTCDKFGWWGSKYLTKRFFEQLHDNYRDRVLFVAAYDKEDDRQPMGMSFCLYKGDRMYGRYWGSLQEIDCLHFDACYYTPIEWAIDRGIQTFDPGAGGRHKKRRGFPATPNYSLHRFYNNRLAQILKSYIGQINEREQAEIDAVNEDLPFTQLPPLLLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Y2</accession>
    <name>A0A2G4F3Y2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56493">
        <property type="protein sequence ID" value="PHX56493"/>
        <property type="gene ID" value="CP500_005235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RNA_methylase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01261">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THUMP" evidence="3">
        <location>
            <begin position="43"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="42099" checksum="FAB0048600E47D63" modified="2018-01-31" version="1">MNQYFATVARGLETIAAQELERLGAQDVRPDFTGVYFSGDRTLLYRVNLWSRTIFRVLMPIAEFPCYNSDMLYGAVQRIPWDEYLNPDNTLAVNCTGGNEKLNHTHYTALQVKNAIADQQRHQFNKRSSVDVENPDLLINIHIHRDRGILSLDSSGGSLHRRGYRPAMGMAPLKETLAAALLDMAEWTPDLPFLDPMCGSGTLPLEASLKALNIAPGLFREKFGFMTWRDFDEPLWDKLWAEAENSELPELKQVVVGCDRDSDMLTQARTNAQQAGLAGKIQFARTELSELEPPSDSGVLICNPPYGERLGDATELGELYKMLGDIFKQRFKGWNAFILTGNKELGKQVGLRTSKRIPVYNGSIPCTLLKYELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F417</accession>
    <name>A0A2G4F417_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56227">
        <property type="protein sequence ID" value="PHX56227"/>
        <property type="gene ID" value="CP500_006595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="5"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13785" checksum="88264B84038BCECB" modified="2018-01-31" version="1">MSNIRLYFDEDIMEKALVQALRVRDIDVMTVGETGRVGESDEAQLIWATVQGRVLYSSNIGDFCRLHNDFIAEGKSHAGIILVSQQRYSVGVKLQGILRLVGNNSAEDMVNQLEFFSKYLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F419</accession>
    <name>A0A2G4F419_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase</fullName>
            <shortName evidence="3">SHCHC synthase</shortName>
            <ecNumber evidence="3">4.2.99.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">menH</name>
        <name evidence="5" type="ORF">CP500_005525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:25597"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:58689"/>
            <dbReference type="ChEBI" id="CHEBI:58818"/>
            <dbReference type="EC" id="4.2.99.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; phylloquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AB hydrolase superfamily. MenH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.20" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56461">
        <property type="protein sequence ID" value="PHX56461"/>
        <property type="gene ID" value="CP500_005525"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00995"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070205">
        <property type="term" value="F:2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042372">
        <property type="term" value="P:phylloquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01660">
        <property type="entry name" value="MenH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022485">
        <property type="entry name" value="SHCHC_synthase_MenH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03695">
        <property type="entry name" value="menH_SHCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="20"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="30266" checksum="42B6429B3F10CB43" modified="2018-01-31" version="1">MDKFKNYNFHYSLTGNKNQPIILLLHGFICDSQDFSPIISLLCQNYCCLAVDLPGHGKTTVSGDETCYNISNVAQALIDLLDDLQINKCLLLGYSMGGRLGMYMTLYFPDRFEKVVLESASPGLKTEKERSHRLQSDLDTAQKLENSNLKDFLLNWYDRPLFQSLKKSPNFHQLIESRLANNPIELAKSLRNMGTGNQPSLWEKLAKNQIPLLLLVGEYDDKFKAINTEIANLCPVASLNIVPKSGHNVHFENIDKFVEIVRQFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F483</accession>
    <name>A0A2G4F483_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar assembly protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56570">
        <property type="protein sequence ID" value="PHX56570"/>
        <property type="gene ID" value="CP500_004810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="377" mass="42660" checksum="D0E51FCA159E6E9D" modified="2018-01-31" version="1">MTRFIHDRFAKEYLEEMLSPIGTVNVGRDVTSEVREIDVYFTPGTPIPEYTQNLGLLGKMACTTAIFEPFRNPIAVSDVWNCTSKLFDLRRELERQARRENTRYDDAKLPFLWILTPTASKSLVSGFGGIPNLSNWLEGIYFFPEHWQGAIVVIHQLPETPETLWLRILGKGKVQQRAIAQLSALATNDPLRMTALELLYRLQSNLVTDTPQKLESEERELIMAITPLFQQQIQAAQQQAREEGLEQGLEQGLEQGLEQGLEQGRQEQQHLILSDFLSGRFGELSPKMSVFLTPLSKLSATEFTRMLLAISMLTVDESGQQQAVKLLAEYVLKRHLNESADILDTAVSNLLKLPVVELTVLVEELPQLSADELRARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4A2</accession>
    <name>A0A2G4F4A2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56592">
        <property type="protein sequence ID" value="PHX56592"/>
        <property type="gene ID" value="CP500_004440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8014" checksum="82FC1DDEBC24952B" modified="2018-01-31" version="1">MGLIRLRVRELAQEKGWTLKEVSDRTGIPYSTVKKYAQAPKMATVDYTALQKLAEVFDLMIEDLVEVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4K4</accession>
    <name>A0A2G4F4K4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56713">
        <property type="protein sequence ID" value="PHX56713"/>
        <property type="gene ID" value="CP500_003610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="205" mass="23316" checksum="BD33433378CF4EC5" modified="2018-01-31" version="1">MTISRSVIRINCLSLLLVGLLTVLTQFSGLKVSDLFFFPYFSPNPSIAFLTRTFQILCSVPVIICTFTYGLAKSLQPRHPENRFILFSALVTGGFLLNEIYRVHIYMIGVGIPKLAVCLLYAVVLSSYGWFCRRDLKSTPYQILLAGWGLLFFAIGIDTLKLKSQIFASLLEGVPKLFSEINIAFYYWYVCKCFLQKILYQSIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4L0</accession>
    <name>A0A2G4F4L0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_004055</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56675">
        <property type="protein sequence ID" value="PHX56675"/>
        <property type="gene ID" value="CP500_004055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="132"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="132"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="231" mass="26136" checksum="7BADE2DFAA5E4D60" modified="2018-01-31" version="1">MAALTLDRNPCVLLVETDEVLAGHLSMDLKSSGYEPIVASNLATGQHLAHELQPALIVIDRMLGGESGLSLCSHIRSVGSRVPVLLLMGRDTVDDRVACLEAGADDYFLKPYRSEDFLQLVRLYLQPDTSSNHQLRFGDLVLDLASRRALRNGRAIDLTMKEFELLKYLMENPREVLTREKILENVWGYDFLGESNVIEVYIRYLRLKIEDEGEKRLIQTVRGVGYVMREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4L6</accession>
    <name>A0A2G4F4L6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sorbosone dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_004110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56685">
        <property type="protein sequence ID" value="PHX56685"/>
        <property type="gene ID" value="CP500_004110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013552151" evidence="2">
        <location>
            <begin position="22"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="3">
        <location>
            <begin position="109"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="446" mass="49249" checksum="9162F1E9AB53034A" modified="2018-01-31" version="1">MYKLRFLLLILLLSVTTCDRATDAQAPGSPEASPLSQIPSQVNTNSPTSQIIPTKPLTPQPIRISPGNLPQPFATDSASKSPQVIPPPQSPILRVPAGFVVNVFADNLDAPRWLALTPTGDVLVTETRQNRIRLLRDANGDGVAEIRQNFATSENGLNIPFGMTFAPGYFFLGNTAEVRRFTYINGQQKLTGTGQKIADLPGGGYNQHWTRNVVISPDSKKLYVSVGSQSNADVEPLPRASVQVMNLDGKNQQTFASGLRNPVGLDFHPKSGQLYTTVNERDGLGDDLVPDYLTRIRQGQFYGWPYTYFKPNLLDPRHVQNGISERPDLAAKTLIPDVLFQAHSAALGLQFYDGKSFPKKYHNGAFVAFRGSWNRNAGTGYKIVFVPFNANFRPEGYYEDFLTGFLTDPSGPKTWGRPVGLLVLPDGSLLFTEEANNRIYRVQYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Q3</accession>
    <name>A0A2G4F4Q3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56773">
        <property type="protein sequence ID" value="PHX56773"/>
        <property type="gene ID" value="CP500_003965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="387" mass="40888" checksum="85FFE2B5219EEE58" modified="2018-01-31" version="1">MDANELLNRYAAGERDFRQANLRGIVLSTIDLYRSSDAPTLILSNLNEHQIRPYLIGANLSGADLTKAHLGRANLSKANLSEANLTGANLTSASLSGANLTGANLTEANLSGSHLNWANMSGAILANANLTGTDMSAANLSKAVLSHANLHKAYLIKANLNQANLKYANLTLASLKDADLSEADLTGAELSKANLAGANLTRANLTKAHLLKANLRRANLTEAYLNHACLGESDLTEACLNRANLTKADLSKTYLRKITLNGSHLSGVNFSGADLSGVDLSRKLLTGINLAEALLNEANFSGAYLMEANLSGANLTQANFSNTYLINANLSDACLHQVDLTKANLSKADLRKADLTGANLRGAILAEADLRGVKLMATILPNGTTYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4R7</accession>
    <name>A0A2G4F4R7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfate ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_003765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic sulfate-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56738">
        <property type="protein sequence ID" value="PHX56738"/>
        <property type="gene ID" value="CP500_003765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902358">
        <property type="term" value="P:sulfate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01005">
        <property type="entry name" value="PBP2_CysP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005669">
        <property type="entry name" value="Thiosulph/SO4-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30368">
        <property type="entry name" value="PTHR30368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00971">
        <property type="entry name" value="3a0106s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="382" mass="41305" checksum="62B0B55AC32DEA4B" modified="2018-01-31" version="1">MSLWQRLTQRLRWSQQQPVGKTQLLTSLKSFVSLFLLGITLSVAVASCGTGGTNNPAASPGASPSATANKGNVELTLVSFAVTKAAHEAIIPKFIAQWQKEHGQTVTFNQSYGGSGSQTRAVIDGLEADIVHLALALDTAKIEKAGLIEPGWEKEVPNEGIVSKSVAAIVTRDGNPKGIKNWEDLAKDGVKLITADPKTSGVARWNFLALWGSVIKTGGDETKALDFTTKVYKNVPILTKDAREATDVFFKQGQGDALINYENEIILAGQKGEKPTYTIPEVNVSIDNPIAIVDKNVTKHGTKEVAEAFVKFLYTPEAQREFAKAGFRPVDATVAAEPEFAQKYPPIKTLFTAQDLGGWGEIQKKFFDDGAVFDKIQGSIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4S4</accession>
    <name>A0A2G4F4S4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-vinyl reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56772">
        <property type="protein sequence ID" value="PHX56772"/>
        <property type="gene ID" value="CP500_003960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004096">
        <property type="entry name" value="V4R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02830">
        <property type="entry name" value="V4R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00989">
        <property type="entry name" value="V4R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="SSF111126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="V4R" evidence="1">
        <location>
            <begin position="130"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="220" mass="24932" checksum="19B88583C6F07CEA" modified="2018-01-31" version="1">MINIADLLKQPRIPGNYFASDAYVRGDLELGLLENRRGDRLLALPETLIKAIYIGLEQETGQASHLVLFNCGRWWGKNFYVRFCEEVSEYYGQPVSEMEMVEFIQCLQQCWKTHGWGTFELDPNYSAQGFLVVKIGNSLFAKTAPKSNLPACFLEAGILSSFFTQLTGRELHCLQTSCESLGSDCNRFILGLRDRLQPADSMVEEGQDHQTIMSQLCQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F566</accession>
    <name>A0A2G4F566_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56879">
        <property type="protein sequence ID" value="PHX56879"/>
        <property type="gene ID" value="CP500_003130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09873">
        <property type="entry name" value="PIN_Pae0151-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044153">
        <property type="entry name" value="PIN_Pae0151-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="8"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="151" mass="16997" checksum="04C3ED7D23710AD2" modified="2018-01-31" version="1">MTVPLRLVLDTNICIKQFIVDPLTPKVNQLFDCLDDPAVEFFVPDLFYIECANVLWKYVRAKLYTAEQVQADLSDLKALRFQVTSTKELMNKAVQIGLDYGITAYDGCYVALSEQVTAPLLTLDERLVNSLTGSEFDVQLFTNFTVPSLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F572</accession>
    <name>A0A2G4F572_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56896">
        <property type="protein sequence ID" value="PHX56896"/>
        <property type="gene ID" value="CP500_002650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="10"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="21171" checksum="FCDF781EA6D179E2" modified="2018-01-31" version="1">MIGIGTKLTLEDFLALPDGDVYYELVDGQAVPKMSPKFFHSTLQFALCSLIRAWCKGRGRVLPEWAVLLKRQGKDWAPVPDLTYISYERLPKIWRRNEACPAIPELVIEIISPDQTMKEFEEKAKDYLAAGVPRVWVIDPEAILIKSFFPDGSSQIYTDNMPIVDELLPGLELTTRLIFEEAELID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5A1</accession>
    <name>A0A2G4F5A1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56919">
        <property type="protein sequence ID" value="PHX56919"/>
        <property type="gene ID" value="CP500_002770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038573">
        <property type="entry name" value="BrnT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007460">
        <property type="entry name" value="BrnT_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04365">
        <property type="entry name" value="BrnT_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="90" mass="10402" checksum="2E5FB42334B0933B" modified="2018-01-31" version="1">MEVEWDPNKADINRQKHGVQFSDAEAVLFDLNALSFEDTTAQGEQRFVVIGMDHLWRLLVVIYTHRGNSVRLISARPATRSERRKYETGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5B1</accession>
    <name>A0A2G4F5B1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_002865</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56936">
        <property type="protein sequence ID" value="PHX56936"/>
        <property type="gene ID" value="CP500_002865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011495">
        <property type="entry name" value="Sig_transdc_His_kin_sub2_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07568">
        <property type="entry name" value="HisKA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="51"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="191"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="270"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="469"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="20"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="673" mass="76156" checksum="B6FC0552B3B3D990" modified="2018-01-31" version="1">MSYYNQSIYKCREIEREYNATSLQLIVAQLRAELNSTREQLHREIDRLTTANETLQAAIRAAPMLLWATDREGKVTLAEGKGLESLGLLSGEVVGNSIFEIYSNYPDVLENFTQVLAGSSRSWNTLQGDLTYEIRSTPMRSSKGEVVGLVSVFTEISDRDRLPVALQIANQELECQLQQQTEVFKTALTESERKYQNLVETSQELIWSVDLEGSLTFVNSAAERIYGYEPPEMIGHRFTDFLLPEHKPLQIQIFEQLLAPNSIQQAVANYAYETVHIRKDGSHVYLRVNSIVNKAENGTILGLTGTATDISDRKRAEAHQTKLISSLQTSEHKFRSLYEATSDAVMLLNEKEFFDCNSATLKIFGCTNKKEFYGKHPREFSPLFQPSGEDSASLSSQQINIAIATGSCRFDWVHKRLDGSEFPAEVLLNVMEINGQKFLQAVVRDITDRKRDEDQIKASLAEKEVLLQEIHHRVKNNLQVISSLLKLQSRYIQDNRVIEMLKESQNRVRSMALVHEQLYQSKDLSNINFAEYIENLAHNLFQAYEVNAAGIKLETNIARCDLNVDTAVPCGLIINELVTNSLKYAFSEKNEGKIKIDFNLDRNGVCVLVVSDTGVGFPKDLDYRNARTLGLRLVGALARQIRGSITLVESVGTVFRITFSQPKLQQERQIYVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5B2</accession>
    <name>A0A2G4F5B2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GuaB3 family IMP dehydrogenase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56929">
        <property type="protein sequence ID" value="PHX56929"/>
        <property type="gene ID" value="CP500_002830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005992">
        <property type="entry name" value="IMP_DH-rel2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911:SF85">
        <property type="entry name" value="PTHR11911:SF85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01304">
        <property type="entry name" value="IMP_DH_rel_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IMPDH" evidence="2">
        <location>
            <begin position="16"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="387" mass="40366" checksum="C11C5980036622CF" modified="2018-01-31" version="1">MNIEIGRGKSARRAYGIDEIALVPGQRTLDPSMADTRWQIGGIDREIPIIASAMDGVVDVRMAVLLSELGALGVLNLEGIYTRYADPQPILERIASVGNHEFVSLMQQLYAEPIKPELIGQRIREIKDAGGIAAVSATPAGASKYGSAVAAAGADIFFVQATVVSTAFLSPESVTPLDLTQFCQEMPIPVILGNCVTYEVALNLMKTGAAGILVGIGPGAACTSRGVLGVGVPQATAVADCAAARDDYYRETGKYVSVIADGGLITGGDICKCIACGADGVMIGSPFARATEAPGRGFHWGMATPSPVLPRGTRIRVGTTGTLEQILRGPALLDDGTHNLLGALKTSMGTLGAKNIKEMQQVEIVIAPSLLTEGKVYQKAQQLGMGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5D5</accession>
    <name>A0A2G4F5D5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56970">
        <property type="protein sequence ID" value="PHX56970"/>
        <property type="gene ID" value="CP500_002470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="7905" checksum="BC65C6383158BC80" modified="2018-01-31" version="1">MGLIRLRVREFAGEKGWTIKEVSDRSGVNYSTLSTYSRSPGMAMVDFTCLLKLARTFDVMAEDLVEVVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5H0</accession>
    <name>A0A2G4F5H0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57034">
        <property type="protein sequence ID" value="PHX57034"/>
        <property type="gene ID" value="CP500_002275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="331" mass="37327" checksum="0CAAB697636F00BC" modified="2018-01-31" version="1">MPTSTDNFYVGDVAFNFHFAGPLLDFEEEIQNQSPFHDLDYLTGEIKRGFLDYVRQGIMLDAIRRLRLYKDEFKSFKNYCEKALGRQYFYCTQIIKAAGICLRLIKAGFEILPSCVAQVVPLFKHAVTDQYGDCPLEEKWQEVVDVVPKEKITAVTISETVDNNPELRLKQIKIKTDTYALLAKKAATAGQSISEFLARLVNEYNPRDLEESAEHTPEQEDILDKLDEEFKKPATEQRLTSAKGKKSQGFGVKVNGKNAKQEVKTEGTEDQVKAKSSGEKVKLKNRQTEIQGEKGSNSFEDKNHEIIGEKSHPGSTATKGSYSEQNSVPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5H3</accession>
    <name>A0A2G4F5H3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57022">
        <property type="protein sequence ID" value="PHX57022"/>
        <property type="gene ID" value="CP500_002205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="25"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="384" mass="43722" checksum="B2FD8EC1DDD1DD43" modified="2018-01-31" version="1">MNTFEHLKIDGFRRLFSAEVEMRPLTVMIGANGVGKSSFLEIFSLLAASAKGQLQSKISELGGISQIVTLDRADSVSISLSMPIENQKPLNYSLKLATKGQFYEIGLETLIQQRNPDAIQPFKYIESRGLDVRYFSPEDERLLRPNWQHSPYETSLAQVPKMYREPETLRQNLASCSFYKAWELNLSPQSPIRLPQSMQPATLPGSKGEDLVSCLYYMRETDPNRFEIIEDTLAVAFPDFERLSFPPVAAGTLAMTWKDRNFSHPFYMHQLSEGTLRFLWLITLLQSRDLTAVTLIDEPEVSLHPELLQLLAHAMREAAQRTQLIVATHSDRLIRFLEPREVLVCDSEDGLTTLTWADAIDLEHWLADYSLDQLWAMNIIGGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5J1</accession>
    <name>A0A2G4F5J1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2203 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57054">
        <property type="protein sequence ID" value="PHX57054"/>
        <property type="gene ID" value="CP500_001865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="123" mass="14137" checksum="2F09D6D2977E6BFB" modified="2018-01-31" version="1">MPQQPSKLNPETPGDESEFVQALETVERSLTAVKERYTQIQVDRQRQAELGNLREDVRKSVRQNPLPELKKELREIEQELEAIELNLESSLFSWGSIKQPFWQAVRFGGLGILLGWILKSYAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5S9</accession>
    <name>A0A2G4F5S9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsH</name>
        <name evidence="5" type="synonym">rps8</name>
        <name evidence="7" type="ORF">CP500_001750</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57144">
        <property type="protein sequence ID" value="PHX57144"/>
        <property type="gene ID" value="CP500_001750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="14926" checksum="00536579536D3C00" modified="2018-01-31" version="1">MAANDTIADMLTRIRNSCMARHQTTQIPATKMTRSIAKVLKSEGFISEFEEAEPEGIERFLVLSLKYKGKTRKPIITALKRVSKPGLRVYSNRKELPRVLGGIGIAIISTSSGIMTDREARRQGLGGEVLCYVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5V3</accession>
    <name>A0A2G4F5V3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secY</name>
        <name evidence="13" type="ORF">CP500_001725</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 12">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57140">
        <property type="protein sequence ID" value="PHX57140"/>
        <property type="gene ID" value="CP500_001725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7 9 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX57140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="434" mass="46897" checksum="D637A2612A8771EC" modified="2018-01-31" version="1">MDVSREKAPTAQETFMQMAQAAGLRGRILVTIGLLILVRLGVHLPVPGIDRVAFSQNVQNSPLIGFLDLFSGGGLSALGIFALGILPYINASIIVQLLTAALPSLEDMQKNDGEAGRRKISQITRYVSLGWAILQSVGIAIWVSPFAQSPAPLFIAQTALALTAGSMFVMWISELVTERGIGNGASLLIFINIVSVLPRSLGQTFELAQSGDTQVVGRVIVLLLVFLVTIVGIVFVQEGTRRIPIISARRQVGRKVYRESRSYLPLRLNQGGVMPIIFASSVLIVPSFLAQSLNNQFLVQVANVLSPSGPAPWAYALFYLTLILFFSYFYASLIVNPVDMSQNLKKMGASIPGIRPGQKTSDYIEKVLNRLTFLGAVFLGLVAIVPTAVESAIGVQTFRGFGATSLLILVGVAIETAKQIQTYLISQRYEGMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Z8</accession>
    <name>A0A2G4F5Z8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1815 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57121">
        <property type="protein sequence ID" value="PHX57121"/>
        <property type="gene ID" value="CP500_001595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014943">
        <property type="entry name" value="DUF1815"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08844">
        <property type="entry name" value="DUF1815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="13048" checksum="95C4CD61CED967C7" modified="2018-01-31" version="1">MFLRLAEQHRRFVQDLVMNLQALAIVLEHRGYLASCYTCGGQMNSASFMVSLTDNHLIRFLVSDYGITWTEMRDDRELMKLEGAEAISQLQELANLVKYHIQPSEATLATAQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F605</accession>
    <name>A0A2G4F605_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplD</name>
        <name evidence="5" type="synonym">rpl4</name>
        <name evidence="7" type="ORF">CP500_001810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57155">
        <property type="protein sequence ID" value="PHX57155"/>
        <property type="gene ID" value="CP500_001810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="210" mass="23643" checksum="461E8F32795CF16F" modified="2018-01-31" version="1">MVNCVVRNWQGEEVGETTLEMRVAKKENASHIVHRALTRQLNNARQGNACTKTRAEVRGGGRKPWRQKGTGRARAGSIRSPLWRGGGVIFGPKPRDFEVKMNKKERRLALRTAFFSRTEDIIVVQEFAEQFPRPKSKELLSAIARWGIEPNKKVLLILPEPQLNVYLSGRNIELVNVILATSLNVYDVLAADKIIITSTAIAKIQEIYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F617</accession>
    <name>A0A2G4F617_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rubredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_000905</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
        <text evidence="6 7">Binds 1 Fe(3+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the rubredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57233">
        <property type="protein sequence ID" value="PHX57233"/>
        <property type="gene ID" value="CP500_000905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024922">
        <property type="entry name" value="Rubredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018527">
        <property type="entry name" value="Rubredoxin_Fe_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00301">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000071">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00163">
        <property type="entry name" value="RUBREDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00202">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rubredoxin-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000071-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="53" mass="5859" checksum="F1A9D85AF322CFFF" modified="2018-01-31" version="1">MQKYVCTVCAYVYDPEEGDPDGGIPAGTPFEEIPDDWVCPTCGVEKSDFEPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F624</accession>
    <name>A0A2G4F624_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GGDEF domain-containing response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_002870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56937">
        <property type="protein sequence ID" value="PHX56937"/>
        <property type="gene ID" value="CP500_002870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="153"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="295"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="553" mass="61860" checksum="BEBBAA4E37C50903" modified="2018-01-31" version="1">MSTKKILIVEDESIIAEDIADSLMDLGYQVTAIVHSGEEALESAAKERPDLVLMDVNLQGEIDGITAGAEMQSRFQIPVIYLTSYADENTLRRVNSTKPFGYIVKPFEEKNLHTTIQLALHRHLYDSLTNLPNRSFLRSRLSQVLEKQTGLPGVIPVFTLSLDKINRINSTLGHDIGDSVLCSIAQRLTNGIENMNIVARLEAAEFALIIEPVLEKQDVVNIAQSILEIVAQVIILEIGEVYVTASIGISLYPGDGIDADEMLKNAYTAMYHAQEKGGNNYQFHAVNTAKYSINRLSQEVCLRNALKRSEFEVYYEPKVEIKTGKIVGAEALVRWNHPEMGRVSPGDFIPMAEEMGLIAPLGEWVLETACRQTQAWQAEGLGPLRVAVNVSSRQFEEKNIIERVCEILTETGLDPKYLELELTESLVLQDEAAVFQAFSVWKNMGIRVAIDDFGTGYASLSYSKRFPFDVLKIDKSFVRNIADDRQNAAITVAIIQMAHSMNMKVVAEGVEDERELAFLCEHGCDEIQGYFFSKALPRADFEELLKSGKRWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F626</accession>
    <name>A0A2G4F626_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57175">
        <property type="protein sequence ID" value="PHX57175"/>
        <property type="gene ID" value="CP500_001855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDc" evidence="1">
        <location>
            <begin position="25"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="214" mass="23756" checksum="20FBA80F10186333" modified="2018-01-31" version="1">MLSNRFSEALIYATELHATQVRKGSGVPYIAHLLGTASIALEYGASEDEAIAALLHDAIEDQGGPTTREAIRSHFGDNVTAIVDGCTDSDTTPKPPWRKRKEAYIDRILTASGSVRLVSAADKIYNARSILKDYRQLGDDVWERFKGGKEGSLWYYRSLVAAFRKAESTPIVEELARIVLELDKLSEDQIDISQKACQEQAGCLFHNNYGRCLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F651</accession>
    <name>A0A2G4F651_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57228">
        <property type="protein sequence ID" value="PHX57228"/>
        <property type="gene ID" value="CP500_000875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7211" checksum="5E62ADDD66811EDB" modified="2018-01-31" version="1">MSIIRQYIAPLIAILVFFVALVAVSARIFLPADMAAPAPIEEVTPEKQAATVNPIFLGLNYSPNRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6B2</accession>
    <name>A0A2G4F6B2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57027">
        <property type="protein sequence ID" value="PHX57027"/>
        <property type="gene ID" value="CP500_002235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="7194" checksum="502F50A2D3AC784A" modified="2018-01-31" version="1">MGPPWRQGMNSLSNSESPLKRTNEFFSPLKRTFALRQGFQPLSDYRFISKFSNSQNGHTDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6C0</accession>
    <name>A0A2G4F6C0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase subunit sigma-24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57298">
        <property type="protein sequence ID" value="PHX57298"/>
        <property type="gene ID" value="CP500_000495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="174"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="824" mass="95083" checksum="5515B1470B14E939" modified="2018-01-31" version="1">MSQPTLRASEQGHRQIQQARNANQKKWVAKEDNFTPLIEASQWLINQYAEAKGWNANDPRWVRNFEQFLRVEKHQDINEIKKKIIQSQQGSLFEILTKLIDEGTAFAHGISYRTWSNFAAPKKCLGINAPAFKAYCHVLGLNWQEIAEETQKKSAKVPNVRQNLPGKDGNFIGREQEIERLMTLLSSDSHSRISIEGCGGVGKTSLALEAAYRCLNANQQNAKVPSFEAIIFTSAKAQFLSGQGISERPNRERTLRDIFQAIARTLDTLNTIPADFNEQQKHIRHSLNQQKTLLIVDNLETLDEQQIVLDFLQDLPITVKAVITTRIQTDFPRILLDSLPLDEGLHLIQQQAEAKAITITLSETAASEIYRKTSGIPAAIVYVVGQLAANYKLENVLNQLLSPTSEVANFCFEGSIQPLRGKLAYQLLMTVALFPHPALEEAIIQTAIPNDRDGEAIDEALAKLQQLSLIKYQEDRYQMISLTREYVLNELKINADFEAAARERWLSWYLKYSQKHGGQDGKEWNNYDELSAEWENIQVVIDWCISQEKYSEFLQFWQQVKGYSYAHSYNRDRLTYWSYRLDWTEWLIEAAKSREDWKTAAEAMCDRAWTLTIVGQAKHLELAESLLKKTWQLRHYQSHTFQIDLAINIAVLRICKQQFKKALLWLKKALLLEKMNQHKDEKSKRQHIHISYYQGKVYFLKEDYEQAKIYYQETLKKSQEIGWERGIALAKNWLGDIAVEQENFDEARLLLEESLQIAQRNQDRSQEAYCKESLAFLAKKQQDLTTATYWANLAIEEFNALGMLPEFERMTVFIQGLSVSREPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6E5</accession>
    <name>A0A2G4F6E5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57364">
        <property type="protein sequence ID" value="PHX57364"/>
        <property type="gene ID" value="CP500_000010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013653290" evidence="3">
        <location>
            <begin position="36"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="208" mass="21202" checksum="ADDF9C82CD8A9054" modified="2018-01-31" version="1">MLSKSLQLNSLSIARYGSSFLLGLLLCTASAPVLAHVGHNSEFAGGDATKIMQPIEVDASKATALGIKTEAIAPTPDGGILKVPSTSLIDANGQKLVYIQEGTTYKPISVQIGSDSGDVVEIKEGNLVSGNQIVTQGATLLYSEALRGKPVPEAQASPGKSEPEAQASPGKSESEAQPAQGSSPLIPIAATGVVLVGVLAIFGLKRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6G0</accession>
    <name>A0A2G4F6G0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoacyl-ACP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57281">
        <property type="protein sequence ID" value="PHX57281"/>
        <property type="gene ID" value="CP500_001180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025528">
        <property type="entry name" value="BrnA_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14384">
        <property type="entry name" value="BrnA_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="85" mass="9703" checksum="3DA508B82B4CD95E" modified="2018-01-31" version="1">MTISPKRLEELENIPESAIDTSDIPELDASFWEKAKLVEPLTKQAISLRVDSDVLDWFKNQGKGYQSLMNAVLRSYVEHHVKSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6S5</accession>
    <name>A0A2G4F6S5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57425">
        <property type="protein sequence ID" value="PHX57425"/>
        <property type="gene ID" value="CP500_000365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="24"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="11"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="113"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="300"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="367"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="401"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="437"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="471"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="505"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="539"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="573"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="607"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="675"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="833"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="867"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="901"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="935"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="1276"/>
            <end position="1456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1557" mass="176225" checksum="CABE22379AE1FF12" modified="2018-01-31" version="1">MSTTVNTESTAVHFNQQGETYLSQGKLEEAIASCEQALKIHPSFAPAYKTLGNALQAQGRMEEARHWYAKAIEIEPNFAEVYANLGSICAQQQKWQEAIAHYQKAIAIKPNFAGVYRNLAKVFGEVGKPAEAQECWYRAFSLEPEKAKPSEHLGMGDAFARQERLPEAIACYDRAIKFDPSLTQAYQNMGEALKKQGKLEEATVYYRKAIELNAANARNGSEGQQTLAGANGANGAVKPPQVQPEVAPQVQQPQVQPQIPEQILRKIPPEILQQIPEQIRQQIQPQVQPPANPGISTEDPEAYKILAEGYFAQGKMEQAISACKKALQIKPEAPLYKMLGNALQVGGKIDEAKTCYVRAIEINPNFAEAYANYGSICAQQEEWQEAISAYEKAIALKPDFAGAFRNYAKLLTQLGKSEEATQCWYRAFAIDPKSGTAEDLENLAKTLIEQGKVNQGIDCYRRAVELNPNAGAAYHELAEILKGQEQWESAVDAYTKAIQINPDLSWSHNNLAESLVKLERWDEAVDAYRRAIELNPDFSWSHNNLADVLLKLERWDEAVEPYQKATELNPDFSWSHNYLADALIKLERWDEAIAAYRRSIELNPDHFWAHNNLAEALVNLERWDEAVAAYQRANELNPNFFWSHSKLGDVLLEMERWEDAVVVYRRAAELNRDFAWTYYNMGTAFEKLERWDESIASYRCAAEIQPDLPWLSQKLADALRMRSQWDLQDAMGLYRRAIDHNPDDVQLYHKALEISPNDAGLYVELANALGRKGWVDGAIVFYQMALQIRPGDRAISAGLEEVLEKKGVVRSAGGDRAVNGNSGSAIEQNPGVATEYHELGESLGQEGKFKEAVAAYRKAIAINPNYFGTHHNLGDILRLLGKVDEAIKSYRKAAELNPSFVWSYHNLGDVFQQENRFDEAVVSYRKAIEVDPNFGWSHYNLAKTLAKQDQLSEALEEYQIASKLDPKLFGLDYQNLRDSLFLGQDPAYTKWRAKHSPRDSDLRKMAETLEIFNYKPLISIVMPAYNTPENYLQEAIESVLNQIYPYWELCIADDASTAPHVKRILKEYAAKDSRIKVAYRTKNGHISHCSNSALELATGEFISLLDHDDTLTPEALYEVVLLLNRHPEADMIYSDEDKIYQDKELINPFFKAEWSPDSFLSRMYTCHLGTYRRKLINEIGGFRVGFEGAQDYDLVLRFTEKTDKIFHIPKILYHWRMHAGSAAGGVDAKPYAYDAGQKALQEAIERRGEPGRIEGVPEFLGHFIARYKIADYKRVSIIIPTKDLGDVLNTCLESIFTKSVYPNYEVIVIDNGSKEKHTAEILAKWESLESARFKSYHLDIPFNFSKINNYAASKAEGDYLLFLNNDTEVITPDWIDAMVEQAQRSSIGAVGNLLIYSDNKIQHAGVVMGLGGGVAGHSYYHMPRSIPGYFGNVVGMNNVSAVTAACLMCRREVFESVGGFDEELTVAYNDVDLCLKMLEKGYRNIYLPHVVLYHHESKSRGYEDSPEKKQRLKKESKLMESKWQKYIDNDPYYSPHLTRACQDSGIRLEDENWRPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUE8</accession>
    <name>A0A2G4EUE8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF29 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000253">
        <property type="protein sequence ID" value="PHX53172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53172">
        <property type="protein sequence ID" value="PHX53172"/>
        <property type="gene ID" value="CP500_022925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002636">
        <property type="entry name" value="DUF29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34235">
        <property type="entry name" value="PTHR34235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01724">
        <property type="entry name" value="DUF29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10561" checksum="E1B726D61D5C72C9" modified="2018-01-31" version="1">MLHIIKWKSQPKKRTASWAISIRSARREIEESQEEMPSLNRDFIESIWEKCFQVSVKDAEDEMGKKGQSTSLSWSEVFEDEYTLSDGDGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUM8</accession>
    <name>A0A2G4EUM8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor SigA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sigA</name>
        <name evidence="9" type="ORF">CP500_022575</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000234">
        <property type="protein sequence ID" value="PHX53235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53235">
        <property type="protein sequence ID" value="PHX53235"/>
        <property type="gene ID" value="CP500_022575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012760">
        <property type="entry name" value="RNA_pol_sigma_RpoD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017848">
        <property type="entry name" value="RNA_pol_sigma_RpoD_cyanobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02393">
        <property type="entry name" value="RpoD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02997">
        <property type="entry name" value="Sig70-cyanoRpoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="349"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="5">
        <location>
            <begin position="157"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="5">
        <location>
            <begin position="324"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="5">
        <location>
            <begin position="181"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="389" mass="45428" checksum="139AB71EB66B7785" modified="2018-01-31" version="1">MIQANTVLETKIKSQMETIDLLRKTESVLPESELELFIDEEDDRDDFSDPQSEEDDTKSAKGVKARRRAQAKKKHYTEDSIRLYLQEIGRIRLLRADEEIELARKIADLLQLEQVREQLLEDLDREPKDNEWASAVQMALPAFRHRLHVGRRAKEKMVQSNLRLVVSIAKKYMNRGLSFQDLIQEGSLGLIRAAEKFDHEKGYKFSTYATWWIRQAITRAIADQSRTIRLPVHLYETISRIKKTTKLLSQEMGRKPTEEEIATKMEMTIEKLRFIAKSAQLPISLETPIGKEEDSRLGDFIESDGETPEDQVSKNLLREDLESVLDTLSPRERDVLRLRYGLDDGRMKTLEEIGQIFNVTRERIRQIEAKALRKLRHPNRNSILKEYIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV48</accession>
    <name>A0A2G4EV48_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methanol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_021675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53405">
        <property type="protein sequence ID" value="PHX53405"/>
        <property type="gene ID" value="CP500_021675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013545371" evidence="5">
        <location>
            <begin position="32"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="TPM_phosphatase" evidence="6">
        <location>
            <begin position="45"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="267" mass="29486" checksum="2C4C36E61AF9A0CC" modified="2018-01-31" version="1">MSQFFPRKFLASAAAFFLALSVWAIAPAAHAFNNPDLLPQIQTPIIDLAKALTDIEEQVLAKNLTEFETETGWKLRVLTQYERTPGLAVKSYWGLDQKSVLLVADPRGGNLLNFNVGDSLYPLLPRTFWVELQTRYGNQFFVRDNGEDRSIIESLESIEGCLRQGGCRVVPGLPREQWILTLIASVLGGVICGFAAQPRKPGQLVAWQWALIFSPLWGILFLAFGVGPVVMRTSEWLPLVRNVAGFAIGALVAFLTPVLGKSPSEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVA1</accession>
    <name>A0A2G4EVA1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphate ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53408">
        <property type="protein sequence ID" value="PHX53408"/>
        <property type="gene ID" value="CP500_021695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="235" mass="26727" checksum="1DE03E135F469E88" modified="2018-01-31" version="1">MLIPLTRETFQELIPAVATGTQYKYIWGKPPDFLRRMLISAVAVVFLLIIYKFAGSDVGPLVLITGLIAGLYWMWAPILWASLKNAECRKYKYCGFWQGRVLDIYITDEVTSQEETVNKKGQLVIVDNLEPRINLEVGDKTGFTTTLTAPLQKSHQGIVPGQAALMLIMSNQEDLGRIAKVSDIYIPSREVWVSDYPYLRKDVFVEMSEQIKKGRQKKAGNNDNRSTKRRSTVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVE7</accession>
    <name>A0A2G4EVE7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000196">
        <property type="protein sequence ID" value="PHX53448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53448">
        <property type="protein sequence ID" value="PHX53448"/>
        <property type="gene ID" value="CP500_021440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="15215" checksum="22F82A0B75A1AEAC" modified="2018-01-31" version="1">MIKVPDWLIYALICSLLYGLWGFFANLATKYIDYKTAFVYEAIGATLTTLFILVKTNNLSFEGDVRGIMFAVLVGVCGTVASLVFFIALGTGKVANVVSVTSIYPLITIVLSALFLKEAITLPHFFGVLFAIIAVILSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVF4</accession>
    <name>A0A2G4EVF4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Molybdate ABC transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">modB</name>
        <name evidence="13" type="ORF">CP500_023015</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000258">
        <property type="protein sequence ID" value="PHX53157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53157">
        <property type="protein sequence ID" value="PHX53157"/>
        <property type="gene ID" value="CP500_023015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011867">
        <property type="entry name" value="ModB_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02141">
        <property type="entry name" value="modB_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="8"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="256"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="291"/>
            <end position="298"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX53157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="616" mass="68327" checksum="6B54079B8FC8A9C6" modified="2018-01-31" version="1">MFANLSPLWISLKTAGIATIATFFLGTAAAYWMLGYRGRWKSLIEGILISPLILPPTVVGFLLLLLFGKNGPIGKLIQQFDFTIIFTWYAAVVAAMVVSFPLMYKTALGAFEQIDSSLLQVARTLGASEKRVFFQILLPLAVPGLLAGITLAFARALGEFGATLMLAGNIPGQTQTMPMAIYFAVGAGEMNEAWFWAICIMTLSLSGIVAVNFWQQRHEQNRHQTKSGLLEANEPVNRGGKSTTPARLGNWIQPQLKETQAGLLVDIEKQLWNFKLDTAFTAKQETLGILGGSGSGKSMTLRCIAGVDTPSLGRIVLNGRSLFDSDKNINLPSHKRNVGLVFQNYALFPHMTVAQNIAFGLQHLPKSVRQQRVDRQLARVQMLRAGDRYPHQLSGGQQQRVALARALATEPELLLLDEPFSALDTYLRSQMERQLVETLATYRGITLFVTHNLEEAYRICEQLMVMSGGKAIAYDSKHQIFEHPKTVRIAQLTGCKNFSRAVVQGSNSVAATDWGITLQVLEALDDRLTDVGIRAHQISITTNPEVDNTYPCWLAATSETPHRMTLFLKFNGMPAGGQDYHVQAEVFKEKWNDLKDRPFPWYVRLDPARLILMVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVG5</accession>
    <name>A0A2G4EVG5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor G</fullName>
            <shortName evidence="6">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">fusA</name>
        <name evidence="8" type="ORF">CP500_021075</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000184">
        <property type="protein sequence ID" value="PHX53525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53525">
        <property type="protein sequence ID" value="PHX53525"/>
        <property type="gene ID" value="CP500_021075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="8"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="17"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="690" mass="75936" checksum="340425BCB9828576" modified="2018-01-31" version="1">MARTVPLEKTRNIGIAAHIDAGKTTTTERILFYSGMVHKMGEVHDGTAVMDSMAQERERGITITAAAITTTWKDHKINIIDTPGHVDFTIEVERSMRVLDGVIAVFCSVGGVQPQSETVWRQADRYKVPRIVFVNKMDRMGANFYKVYGQICDRMRANAVPIQIPIGSEENFRGIVDIVQMKAYIYNNDTGTDIEEIEIPDEVKDLAVEYRTKLIESVAETSDALTEKYLEGEELTEDEIRSALRHGTVEGTIVPMLCGSAFKNKGVQLLLDAVIEYLPSPLEVPAIQGLLLGGDTAERHADDNAPLSALAFKIMADPYGRLTFVRVYSGILKKGTYVLNSTKDKKERVSRLIVLKSDDRIEVEELRAGDLGAVLGLKDTFTGDTICDETAPVILESLFIPEPVISVAVEPKTKQDMEKLSKALQSLSEEDPTFRVNVDPETNQTVIAGMGELHLEILVDRMLREFKVEANVGKPQVAYRETIRKAVRAEGKFIRQSGGKGQYGHVVIEIEPGEEGSGFEFVSKIVGGTVPKEYIGPAGQGMKEACESGILAGYPMIDLKATMVDGSFHDVDSSEMAFKIAGSMAIKEAVMNATPVLLEPMMKVEVEVPEDYIGNVIGDLNSRRGQIEGQETDQGIAKVSVKVPLAEMFGYATDIRSKTQGRGIFTMEFSHYEEVPRNVAEAIIAKNKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVI7</accession>
    <name>A0A2G4EVI7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000180">
        <property type="protein sequence ID" value="PHX53544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53544">
        <property type="protein sequence ID" value="PHX53544"/>
        <property type="gene ID" value="CP500_020925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="278" mass="33156" checksum="09878D1B1826CF1C" modified="2018-01-31" version="1">MFSIYILTYNEEIDIAACIESALLCDDIIVVDSFSSDRTLEIVQRYPVQIVQHPFETHGLQRTWMLQEVPCKYEWVYILESDERMTPALFAECLKAIESQEYIGYYVAEKVIFMNRWIRRSTQYPRYQMRLFRKDQVWFSDYGHTEREVCKGPTHFLKETYPHYTCSKGLSRWIEKHNRYSTDEAAETLRQLTAGQVNWWDLLFGASEVERRRALKDFSLRLPLRPVVRFFYMYILLGGFLDGQAGLAWCTLQAFYEYLILLKVWEMKHMPLPNLDPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVN5</accession>
    <name>A0A2G4EVN5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Penicillin-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mrdA</name>
        <name evidence="6" type="ORF">CP500_022625</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000236">
        <property type="protein sequence ID" value="PHX53227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53227">
        <property type="protein sequence ID" value="PHX53227"/>
        <property type="gene ID" value="CP500_022625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017790">
        <property type="entry name" value="Penicillin-binding_protein_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03423">
        <property type="entry name" value="pbp2_mrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="5">
        <location>
            <begin position="75"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="4">
        <location>
            <begin position="277"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="606" mass="65537" checksum="5CFA07F166035F56" modified="2018-01-31" version="1">MQRQIYSISGFRSSDQTLGETPKKQSRPMQRAIVLMLIATGLLSLHVCRLVQLQLVEGKQNRERAENNRVRLVPMPANRGHIIDRKGKLIAANNLARSIYLWPKEQTPEQWKVTADKLSPLLKIPAKEILEKIKQVDPLSYRPVRLRQAMPPEVFVPLSEKVGQMRGVEVRPEARRYYPEGSVAAHVLGYIGEATQADLKAHPEYPMGMIVGQMGIEASSNSKIAGVWGDRLIEVNAQNQELRLMGETPPKPGESVQLTIDLEMQKAAEKALGNRRGAVVALDVKTGGVLVLASHPTFDPNLFTRKITKEEWETLQGLENPFLNRAMQGYPPGSTFKIVTSVAGMESGKFSPDSIIGTSSYITVGGINFNEHSGGYGDIGFRDALAFSSNTFFYQIGMSVGPEQISKWGHLLGIGKDTDLKLLGLGGGDHGQIPTPEEKEKIYKEPWYVGDTVTTAIGQGLVLVTPLEAAVMVSSIANGGDRVKPHLLASMTGTPETKPVPTGMKPSTIAVIKQGLVAVVTEGTGRGLNDGSIPLTGGKTGTSEVIGQKDHSLYVAYGPAEKPEIAIAVVVENGGFGSVAAAPIAKQVFQAYFGKPKQVNESVINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW25</accession>
    <name>A0A2G4EW25_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_020330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000166">
        <property type="protein sequence ID" value="PHX53660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53660">
        <property type="protein sequence ID" value="PHX53660"/>
        <property type="gene ID" value="CP500_020330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="77"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="296" mass="33140" checksum="8C7AA54EF5DFB988" modified="2018-01-31" version="1">MVPIKSGRFNWLDNESIAAWTFLAPALLFLGTFLIYPIAYLFYLSFTSGSFTRSGIHFIGLKNYWRLVANLDFWQVIQNTIYFATFTVIPSVVIPLGLAVFLNRSFAWRGVLRTAYFVPSITSLVAVGLGWRWLFQAEGPVNGLLMAIGLNPIPWLSSTVWAMPVIILLSIWKQLGFNMVVFLAGLQAIPVNHYEAAELDGADAWQQFWYITLPGLRSTLVFASVTTAIFTLRSFEQVYVITGGGPLNSTNLLVYYIYDQAFTKFDFGYAAAAATLLMAVTLGLVYLQLKVWGEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW54</accession>
    <name>A0A2G4EW54_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53765">
        <property type="protein sequence ID" value="PHX53765"/>
        <property type="gene ID" value="CP500_019815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007165">
        <property type="entry name" value="Phage_holin_4_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37309">
        <property type="entry name" value="PTHR37309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04020">
        <property type="entry name" value="Phage_holin_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="12445" checksum="72428D89689E9639" modified="2018-01-31" version="1">MEPIVFLIAWLVTGSSLLLISQLPIGVEIDSTPKAVFAAAVLGILNVLILPILKAVFFVPNVLTLGLLSGLFAFVMNVIIFATAAKLVEGFSLRMGIWSAVLGALALALVSSLINGVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW76</accession>
    <name>A0A2G4EW76_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH:ubiquinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_021485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CIA30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53437">
        <property type="protein sequence ID" value="PHX53437"/>
        <property type="gene ID" value="CP500_021485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="PTHR13194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="3">
        <location>
            <begin position="55"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="CIA30" evidence="2">
        <location>
            <begin position="181"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="3">
        <location>
            <begin position="350"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="487" mass="53753" checksum="B9E664FBDF90B297" modified="2018-01-31" version="1">MTEKNTAQWDAGRFVKTLAYFGVIPFIGSISWLQQLFGSSRNTQKDQPKLVLVAGATGGVGKRVVKRLQQRGIRVRALVRDTKRAQEILGQNVELVEADITLPETLTRLVTDGVEAVICCTGTKVQPIEGDTPNREKYYQGIKFYMPEVVDVPEIVEYKGLNNLVQAVRSQLIKAGEKTIFDFTKPTQDLKETWGALDDVVMGGTSESSIRLTDNTALFTGNVSTANSGGFASVRTRNFDSAIDLTGFSGIQLRVKGDGKRYKLIVRSESKWDGIGYCYSFDTVYNIWITITIPFEKLIPVFRAKTVKDGSKLNTKTIYSFQLMLSKFEYDGALNPKFTPGIFQLQLESVKAYADQELPRFVMVSSAGVTRPGRPGINLEEEPPAVRMNEMLGGILTWKLKGEDCVRSSGIPYTVVRPCALTEEPGGKALMFDQGDNIRGKVSREDIAELCVQALDLPDACNVTFEVNEGENGKAAGDWQGLFSGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWB2</accession>
    <name>A0A2G4EWB2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4327 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53811">
        <property type="protein sequence ID" value="PHX53811"/>
        <property type="gene ID" value="CP500_019545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025477">
        <property type="entry name" value="DUF4327"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14217">
        <property type="entry name" value="DUF4327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="9086" checksum="A88C7A5D8F1964EA" modified="2018-01-31" version="1">MIQSTIHQLQYSLDVIQDEARHLVHDGVLSRQQPIYTLCQFIPPREWACVECELEKCDFLLRDRIADLIGSEKWDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWB4</accession>
    <name>A0A2G4EWB4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_019910</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53730">
        <property type="protein sequence ID" value="PHX53730"/>
        <property type="gene ID" value="CP500_019910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="21"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="311"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="405" mass="42847" checksum="04BAABA06F49659C" modified="2018-01-31" version="1">MDIVESVKMAVTTLTGNKLRSSLTMLGIIIGNASVISMIGIGEGAKTFIAGQVNSLGSNLLFIIPGSPEAQSRPVIPPQTLVVEDAEAIASQVPSVEEVAPTLNDSQLVTFRNKNVSSSIVGTTPEFLTVRSFDVAQGRFLSKLDLQREENVVALGSEAAEQLFGNSQPLGQYIRIKNSTFQVIGVMQGKGSSFGDNQDMNVYLPLTTMANRIVGRSSPYGTKVTFISVSIKDESQMKAAQFQIENLLRLRHKITKEDDFTVRNQKDLMKILGTITDGLTLMLAFVAAISLFVGGIGIMNIMLVSVRERTKEIGLRKAIGASQQDILIQFMIESVILSAAGGAIGTGFGIGGVLLVAAFTPLQASVSVGAIALAVGVSGSIGLFFGIVPAKQAAKLDPIVALRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWF4</accession>
    <name>A0A2G4EWF4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MoaD/ThiS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000187">
        <property type="protein sequence ID" value="PHX53507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53507">
        <property type="protein sequence ID" value="PHX53507"/>
        <property type="gene ID" value="CP500_021165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="9796" checksum="5E234609836345ED" modified="2018-01-31" version="1">MTVTVLIPTPLQKFTNNQATIECGGANVSELIESLETHCPGIKKSLCDEQGAPRRFLNFYVNSEDIRFLEGTETALQDGDQVSIVPAVAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWP4</accession>
    <name>A0A2G4EWP4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metal ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_018630</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000135">
        <property type="protein sequence ID" value="PHX53965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53965">
        <property type="protein sequence ID" value="PHX53965"/>
        <property type="gene ID" value="CP500_018630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="279" mass="29828" checksum="E35CE6C28834FEB9" modified="2018-01-31" version="1">MLNLLIEPLKFEFMRNAIAIGVLLGILCAVVGSYLIVQQMGMMVDMIAHSVLAGLPVAFALGFNIAIGAFISGMISAGIMAWIQSQSRIKIDAVMALLLSTFLALSITLISLLRTTKLDLDGFLFGNILSVAPTDVQQTFFTTLIILVAVKVFYKELLFYTFDPLGAQASGLPVNWIYLGMISAITLTIVASLQTVGALLVISLLIGPGITAYLLVKELHLIMGLGSAIGITATITGMYLSYYLNMPSGAAIVLVVFALFLLALLFSPSQGILTRKKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWV6</accession>
    <name>A0A2G4EWV6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carbohydrate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_018710</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53958">
        <property type="protein sequence ID" value="PHX53958"/>
        <property type="gene ID" value="CP500_018710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="5">
        <location>
            <begin position="5"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="326" mass="35326" checksum="84AF75632850714E" modified="2018-01-31" version="1">MTYPRVLCLGEILFDYLADRSGFTLEQVESWTRYPGGAPANVACALVKLGIPAGFIGAVGGDELGDSLVKVLQEVGVDTTGVQRHSTAPTRQVYVLRNEMGDRSFVGFGECSTVEFADTHLLAAQIPDILFENAEFLVLGTLELAYPDSREAIKRAIELAEIHNIKIIADINWRPVFWPNPDEAKPQIKELLKKVDFLKLSDEEAEWLFATTDAGAITYRLDSPEGVFVTAGDRGCSYCISENEGKIPAFRVDVEDTTGAGDGFVAGLVSQLCKVGIKSLSDAETTKKVVTYASAVGAMTAMKPGAISAQPTASEVEAFLYLYENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX30</accession>
    <name>A0A2G4EX30_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Thiazole synthase</fullName>
            <ecNumber evidence="4 6">2.8.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">thiG</name>
        <name evidence="8" type="ORF">CP500_017940</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:26297"/>
            <dbReference type="Rhea" id="RHEA-COMP:12908"/>
            <dbReference type="Rhea" id="RHEA-COMP:12909"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="ChEBI" id="CHEBI:77846"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="EC" id="2.8.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer. Forms heterodimers with either ThiH or ThiS.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ThiG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.10" evidence="4 6"/>
    <dbReference type="EMBL" id="NXIB02000125">
        <property type="protein sequence ID" value="PHX54102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54102">
        <property type="protein sequence ID" value="PHX54102"/>
        <property type="gene ID" value="CP500_017940"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990107">
        <property type="term" value="F:thiazole synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04728">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00443">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033983">
        <property type="entry name" value="Thiazole_synthase_ThiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008867">
        <property type="entry name" value="ThiG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34266">
        <property type="entry name" value="PTHR34266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05690">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiG" evidence="7">
        <location>
            <begin position="89"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="274"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="296"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DXP" evidence="6">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="347" mass="37206" checksum="40B1797074CC3203" modified="2018-01-31" version="1">MGSVFQEFEEIVNSGIKNNMPHDARLIIVGEILYAVTRDELTNKEGWLLENMLGGREKWEKGLEYAIFGDPKQGHIAPPLTISDKPLIIAGKTFHSRLMTGTGKYRSIAEMQQSVNASRCEIVTVAVRRVQTNAPGHEGLAEALDWTKIWMLPNTAGCQTADEAIRVARLGREMAKLLGQEDNNFVKLEVIPDAKYLLPDPIGTLEAAEQLVKEGFAVLPYINADPLLAKRLEEVGCATVMPLGSPIGSGQGINNAANIQIIIDTVKIPVVVDAGIGTPSEAAQAMEMGADALLINSAIANAQNSPAMAKAMGMATEAGRLAYLAGRMPIKDYAIASSPQTGTVTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX35</accession>
    <name>A0A2G4EX35_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000124">
        <property type="protein sequence ID" value="PHX54112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54112">
        <property type="protein sequence ID" value="PHX54112"/>
        <property type="gene ID" value="CP500_017890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="12"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="200" mass="22894" checksum="12A58AB004DAFE82" modified="2018-01-31" version="1">MIATVTKKLTFDQFLVECPEDGRYELVNGEIVKMNATRNHDDVANVMLFDFNDEIRRLNLNYIVNNTAVIRTVTKTGIAQGRRPDVSVIDRDLWYSNRSAYAAMQEPIQLAVEVTSTNWDDDYIDKLDEYRRLGIPEYWIVDYLAIGSREFLGNPKVPTIFVHLLDADGNYQTTTFKGSERIVSRTFPGLTLTAEQVMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX52</accession>
    <name>A0A2G4EX52_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000124">
        <property type="protein sequence ID" value="PHX54109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54109">
        <property type="protein sequence ID" value="PHX54109"/>
        <property type="gene ID" value="CP500_017875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="231" mass="26927" checksum="1C7811968046472F" modified="2018-01-31" version="1">MQAQEIKEQLKSLISEAYPIDPSLARRLDEIYRWVKDVKPGSLTAKKFVMAFLLQLVTDSEVWLAVKSLPSDAEQQAAFELMSSAERYWYSYLFPKWLSETDRKLYIWKKKLMAGDFYPADEQILQSLIAQIQQREDASFIQRYIADLSMATDSIVSSRQHQPLCIQITSISDEFSQQKYENWQKTLQEWGIDRGLFLSYDPSIESSVDRLVNMALYNSDNLQAGRYLKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX53</accession>
    <name>A0A2G4EX53_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53727">
        <property type="protein sequence ID" value="PHX53727"/>
        <property type="gene ID" value="CP500_019895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13924" checksum="FCDA1B93B4E76984" modified="2018-01-31" version="1">MQIILEVSDRLGEQLQEFGDRLPEVLDRALREITATETISYQDDRQIIELLASQPSPEAILAIRPTPALQARMSELLDRNKSGNLSRLEEVELDRYLLLEHWVRLAKAHAYKRSQTVASAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX56</accession>
    <name>A0A2G4EX56_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_018230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000129">
        <property type="protein sequence ID" value="PHX54056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54056">
        <property type="protein sequence ID" value="PHX54056"/>
        <property type="gene ID" value="CP500_018230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9_N" evidence="4">
        <location>
            <begin position="11"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="492"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="709" mass="79002" checksum="21892EC919B5886C" modified="2018-01-31" version="1">MAKFDRAFSYPTTRKIDQTDDYHGIPVSDPYRWLENPDSEETQAWVKAQNAVTFGYLKEIPAREKIKQRLTQLWDYEKYGIPFKEGDRYFYYKNDGLQNQSILYTLTSLDGEPKVLIDPNTLSEDGTVALGGIAISEDGKFMAYGLSTSGSDWQEWKIRDIETGADLSDHLKWVKFSGAAWTHDGQGFFYSRYDEPNEKSKHEDVNYYQKLFYHRLGTAQSEDVLIYDRPDQKEWGFSGGVTEDGKYLIISVWQGTETKNLIFYKDLTAPESAVVELISEFEAEYNLIDNEGSVFWFQTDLNAPLGRVIAIDINNPPPSSLAGDETPPSPPLTKGGIQGGFTEIIPEAAETLGGIGILNNQFVTSYLKDAYTQLKIFNLDGSFVRQIALPGIGSAGGFGGKRHETETFYAYTSFTTPNTIYSYNMLTDESTIYRQPKVDFNPDDYETKQVFYPSKDGTQVPMFITHKKGLQLDGNNPTYLYAYGGFGISLTPSFSVSRVVWLEMGGVYVTACLRGGGEYGEAWHQAGTKLNKQNVFDDFISAAEWLIANKYTQPAKLAIAGGSNGGLLVGACMTQRPELFGAALPAVGVLDMLRFHKFTIGWAWTSEYGSSENAGEFPTIYGYSPLHNLKPGTVYPATMITTADHDDRVVPAHSFKFASALQEMHGGENPVLIRIETKAGHGAGKPTAKVIEELADEWAFLVRELDINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX59</accession>
    <name>A0A2G4EX59_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">smpB</name>
        <name evidence="3" type="ORF">CP500_017805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SmpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54119">
        <property type="protein sequence ID" value="PHX54119"/>
        <property type="gene ID" value="CP500_017805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="18174" checksum="15A179CB5EBAF6F3" modified="2018-01-31" version="1">MSEKSPGYKILSDNRQARHLYEIIDTYQVGVELKGTEVKSIREGKANLRDGYALVQSGELWLINVHISPWRSASNYFNHEPRRTRKLLMHKQEIRKLIGKVEEKGLTLVPLKMYLKGGWVKLDIGLGKGKKLYDKREDMKKRDDNRDMQRAMKQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXF1</accession>
    <name>A0A2G4EXF1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54158">
        <property type="protein sequence ID" value="PHX54158"/>
        <property type="gene ID" value="CP500_017685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027372">
        <property type="entry name" value="Phytase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13449">
        <property type="entry name" value="Phytase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Phytase-like" evidence="2">
        <location>
            <begin position="99"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="434" mass="47417" checksum="19AD040F17ECCA60" modified="2018-01-31" version="1">MSQIWHKSQQLNKAGKIQFTALSNYFDFKTVGDPLRWRSPRRGGLRQRILRLFSLTLILLIMCTACAPPPAAAKDRSFPEMSLEFLGEYQLPKMSFEGTPVGGLSGITYDSKGMNEATSQAYRFYALSDDPSENGEARFYSLRLDLKSGDTANIGLKKVTVEGVTSLKKADGETFPWGSINPEGIALSPRNSVFVASEGVTHVGIPPFVGEFDLKTGNQRGNLPIPKRYIPDSSDDKQQQGVLDNLGFESLTIDPETFSPGGIDPFRLFVGTEAPLMQDVDPENGTKLRILHYIIVDKTPQLVSENLYGLDSVPMSILNGLTELVAIGGGQFLSLERSFGISGYGGRIYQVAVGAATDTSRINSFKGQTTMLEPVRKKLLLDLSELGIPLYNLEGMTLGPRLPDGSQSLVLVSDDSFDEAQQTQFILLSLKGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXN4</accession>
    <name>A0A2G4EXN4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel protein MscS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_017065</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54281">
        <property type="protein sequence ID" value="PHX54281"/>
        <property type="gene ID" value="CP500_017065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="372" mass="41525" checksum="B8A05D6F74612923" modified="2018-01-31" version="1">MEAVWDTLKNINYSGIPIAKIAVVIIILTLTQTLRRFFVAVIVKTIERFTKKTETTLDDELIAIIKPASSWLILIGGFSLSKEILAENLGSQLNQTIGSTLNYIVIFIVAYVVYRGSSILGQVIANVLLHTETELDELLRPLMPKIFQSAAIIVLAIKISEIFLGQSAAALVGLLGGAGITFGLLLKDIVYDWFCTLIIYSDNLYREGDWVGISGVEGFVQILHIGFRTTTLHIYQWGSIMKMPNSKMISGIVENWSQNPGSELKWGLSLTLKIDGISSKQTARICDALREMPSNIKGLSKEIIVRFSKIEDNARVIKVVAFVNDDNLYFDAEKNLNLAILELLEQEGIDFLHVELRTEPEKYKQSLQVTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXT1</accession>
    <name>A0A2G4EXT1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000135">
        <property type="protein sequence ID" value="PHX53967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53967">
        <property type="protein sequence ID" value="PHX53967"/>
        <property type="gene ID" value="CP500_018650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="146" mass="16757" checksum="386B5477F1646880" modified="2018-01-31" version="1">MILVQNTTKNMEENFLLLNELAKRLSYKPGYSFLIRRIDNEKALISLRCPSLPNSQEEGEEVGLTINNTVKLSAIVTPSDALHAFAKVVASLELHESAEWFKIDDRQVFLPHGWEDEFGGFKWEDFMNLNGKFLRALKNFIEQPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXU0</accession>
    <name>A0A2G4EXU0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_016490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54353">
        <property type="protein sequence ID" value="PHX54353"/>
        <property type="gene ID" value="CP500_016490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009584">
        <property type="term" value="P:detection of visible light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013515">
        <property type="entry name" value="Phytochrome_cen-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00360">
        <property type="entry name" value="PHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0716">Sensory transduction</keyword>
    <feature type="domain" description="PHYTOCHROME_2" evidence="4">
        <location>
            <begin position="27"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="6">
        <location>
            <begin position="474"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="5">
        <location>
            <begin position="616"/>
            <end position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="878" mass="98938" checksum="8B55B465D182571A" modified="2018-01-31" version="1">MIKMSKSVLEQEDLLNRITTRIRHSLELQEILTTTVIELRNLLGGDRVKIYRFEPDGSGEVIAESINGNNLPSLLGLHFPTGDIPKSAREMFIKARQRVIVDVGLKHQTINRLDCPETGKTLDAEDIRYSAVDPCHIEYLRAMGVHSSLTVPILHHNQLWGLLACHHTQPKRFSDRELKIVQLLVDQLSIAIAQSALLSQARQQARDEAIVNQISSLLHSPLELAEIRHTVLEQTVKALQGSGGRLYIAPEGVDWPAELYTCGQQPQNLEIEKSQFWQKIMGFKNSNPVATYDATNLHKIKIFPSIDLDEYNQIDLIISDYIIPELYAISDISKEPKIKSLSSHFLEVSIRSILAVPLQYRDQCIGCLTIFRNEIETETLWAGQREIEARNDRPRKSFAAWKEIKTKQGREWKNDEMKLAKYLGTHLYMATMQRRVEAMIRHQASHDQLTGLANKFLFNEQLSLAVANANHNGETLAVIFLDLDGFKNVNDTLGHAVGDQLLKSVAGRLTNCLRGGDSIARWGGDEFTLLLYNISCAQDATDTCQRILDSLCTPFRFEELELYIKASLGIALAPYDGEDAETLLKNADAAMYKAKQKGRNNYQFYTTAIGNKASERLRLENNLYRALENSEFLLHYQPQIDLNTGKIVGLEALVRWEHPERGFMAPDQFIPLAEETGLICQIDEWVLRTACLQNRAWQLMGLPPMRVAVNLSARQFQQNNTVKTIAQILSETGLDAEYLEIEITETIAMTDVNFTVSVLQQLQQMGIHISLDDFGTGYSSLWSLKHLPLNSLKIDRSFVADLMSGSSGAAIVKMAIALGQGLNLQVIAEGVETPEQLEFLHSLQCDMAQGYFFSKPISAAAIEQLCMENRVWKMMVNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXU5</accession>
    <name>A0A2G4EXU5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54298">
        <property type="protein sequence ID" value="PHX54298"/>
        <property type="gene ID" value="CP500_016815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="16570" checksum="6C0108004F009C98" modified="2018-01-31" version="1">MLDLAIIIPEIVKYGGAERVVIECLARWQHHHRITLYATSIDYKVVREFCPEIRFTFVQLSPYFQGEYAFFLNGTLLPKLWQQEIGTHDLYHTHLWPCHLIDRHPMVWYPHEPPRMLEDLRLSQFPEANPSDVWKVDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXY5</accession>
    <name>A0A2G4EXY5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000104">
        <property type="protein sequence ID" value="PHX54393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54393">
        <property type="protein sequence ID" value="PHX54393"/>
        <property type="gene ID" value="CP500_016420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="PTHR23426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="98" mass="10870" checksum="4248EF5F4C692CFF" modified="2018-01-31" version="1">MANIKFVKENQEVIAADGANLRLKALENRIDLYTFAGKMMNCGGYGQCGTCIVEIVEGSENISPRTDFENRKLKKKPENYRLACQAMVNGPVSVKTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY00</accession>
    <name>A0A2G4EY00_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AI-2E family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_016355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54414">
        <property type="protein sequence ID" value="PHX54414"/>
        <property type="gene ID" value="CP500_016355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="360" mass="39474" checksum="D7C6B55595952FEC" modified="2018-01-31" version="1">MNSIFSPVQQFLITWLLVLVTGWFTLTAINYVGELVSILVTAGLLAFLLNYAVVRLQVFLPRGVAAALVYLTAGLLLVVIGLTIVPPVFSQARQLGVRFPELLESGRQQLGEFQIWSADRNLPFNVEILEQQLSAKVQEQVQAIAGTSLGLVVGTVNWFLDLILILVISFYMLLDGQRVWGGLTSIFAPDIRFVLTETLQRNLQRFVSGQLLLGLFMATALTLAFWWLRVPFFLLFAVFIGLTEIIPFIGATLGIGAVSIIVAFIDWWQALQVLAVAIALQQVKDNVVAPRIMGNLTGLSPVIIFTALLLGGRVGGLLGVILAIPLTGVVKSIVEIVLNPQLPPQTGSFFYNPFKDEELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY72</accession>
    <name>A0A2G4EY72_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54117">
        <property type="protein sequence ID" value="PHX54117"/>
        <property type="gene ID" value="CP500_017795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="152"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="241" mass="27140" checksum="9C43718032E86510" modified="2018-01-31" version="1">MLNMKPLANAPNTGKQPPKKPHNSKWAALLLMLAVGFGGWQIGLPELAALFNNRGFENYKANKLAETQESYQLALSLDSKNRTALYNLGWLCEEVQDLGCARGKYREAAKLGLPAAYSNLARLYILHDKNYPAAVHLLLQGLKLAKDDQVKYSLFKNLGWARLKQARYPEALQHLNAAIKIDSERAATNCLKAQVLEGMKKTQEAQPLWKICLKYADSQELDEDIWIGMARQSLKEEKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY81</accession>
    <name>A0A2G4EY81_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_016065</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54446">
        <property type="protein sequence ID" value="PHX54446"/>
        <property type="gene ID" value="CP500_016065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041122">
        <property type="entry name" value="RecJ_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17768">
        <property type="entry name" value="RecJ_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="6">
        <location>
            <begin position="88"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="7">
        <location>
            <begin position="434"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="RecJ_OB" evidence="8">
        <location>
            <begin position="507"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="778"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="853" mass="95882" checksum="5FFD8EB079569935" modified="2018-01-31" version="1">MTEQSQNWQTQPLPQPPAWLIQAVNKHAPELPGKYAAALLWCRGIQNPEQIPGFLNPKLYQPASPWEFGQEMNWAIDRIQQARNSGEQVAIWGDFDADGITSTSVLWDGLGEFFAQNDRLTYYIPNRLTESHGLNIPGIDNLAKSGISLIVTCDTGSTNIAEIEYANSLNIDIIITDHHTLPDDRPPATAIINPRYFPPNHPLFHLSGVAVAYKLIEALYETLPDIPQRDIEELLELVAIGLIADLVQLTGDCRYLAQLGIEQLQKQINNPTRPGVAKLLELCKRNGDRPTDISFGLGPRINAVSRIQGDASFCVELLTSRDKKRCEELALLTEIANTRRKSLQKDVAKDAAAKLAQLDLSTTSAIVLADPQWAVGVLGLVAGQIAQEYGRPVILFSTEGTAEINESLPENQFVESLNPELPTLPQSKIQNPKSKIARGSARSANQIDLYQLVKDQAHLLDRFGGHPFAAGLSLPIENIPLFTDAVNQQLRQKYSNESLTAAPVQADLTISVSELGKDLFQELKLLEPCGMGNPAPKLLIENCWFENVWNQKIKDLKGQKIEYIKTQFTIWDESSDGGFRGIWWGHYQHEIPQGRCDAVVELDFNTYEKKYEVRLIAVRSRKVENQINPTHQIDWIVDWRNRNQDQELLAANKKLVSEMLAENLVDNSEICDRQNSLILQECPTSWDELRIWFRQAQHNQQKLAMTYTLPPPVPPVQIWEQLIGIAKYLSRTSKPVTRQQLRQKLGISDTSLQLGFKTLTYLGFKVNYRDRAFHITRQSETGNAPKTGNKGDKFLQPSSPNSSSQLAHSAAKFLAAVSEEQFRRKYFCEVPLSTIQSIARETFFPEDSTAIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY82</accession>
    <name>A0A2G4EY82_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3252 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54127">
        <property type="protein sequence ID" value="PHX54127"/>
        <property type="gene ID" value="CP500_017850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021659">
        <property type="entry name" value="NdhS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35494">
        <property type="entry name" value="PTHR35494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11623">
        <property type="entry name" value="NdhS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="7006" checksum="5D2F1FE274BDC336" modified="2018-01-31" version="1">MIFPGSAVRVKDTTEIYYGFQGLVQRVTDGKVAVLFEGGNWDKLISFRLSQLELVDATAGRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYJ5</accession>
    <name>A0A2G4EYJ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54602">
        <property type="protein sequence ID" value="PHX54602"/>
        <property type="gene ID" value="CP500_015095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="83" mass="9183" checksum="7FD3345D8838F929" modified="2018-01-31" version="1" fragment="single">LTIKSRSPHLPISPSPHLNRSGESKNKSPNIKTFFRVGQKYIKKLNVVIRPMCLLGIIMVGKLQIASSKFSKIATPAKVELLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYM0</accession>
    <name>A0A2G4EYM0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_015215</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54625">
        <property type="protein sequence ID" value="PHX54625"/>
        <property type="gene ID" value="CP500_015215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="217"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="251"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="285"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="4">
        <location>
            <begin position="633"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="689"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="706"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1036" mass="116502" checksum="6A123E8EA075945E" modified="2018-01-31" version="1">MLNKIWRFLKQLIQRLFGTNPKIEPTPPQPRPTLTDAEYEAKLMELLEGVNQGWGRGDVAEFLIAKQIKNGDLAAWLRRFGDRLLEGAQGSTASADAVVSLQELARRLELLGGVAGGELGECAGNVGREILVEFPVVSGEGGEGVDGKAEEWKKRGNEQYNLGNFEDAIASYDKALEFKPDYHQAWYCRGYALYKLGLFEDAIASYDKALEFKPDLHTVWNNRGYTLDDLGRLEDAIASYDKALEIKPDDHEAWNNRGIALRNLGRLEEAIASYDKALEFKPDDDAAWLNRGVALYRLGRFEEAIASYDKALEIKPDYHSAWFNRGIAVKNAPGYNQLVYEILQGQFPNSPPVTRTLLTHNLKQRGYEGQVLTLQAGLEYCHQNTHPEGYGQLHQALGNAHYSRGKLNSPNTYWNKAATSYQEALKTLTPDAFLKLHLEVLQKLIKTLVSLKQTEEAKRLQRYATELLHGLLQQQNYSQLTQQQLTDKLVSFEQLTVNIFIQSGQFAEALATAETDKNVCLSWLLDALPIPDYETEETVTHAQIQQLLNPTTAAIYWHLSDAALTTFIIKSDGLLSPETCLSDFPDEFEEWVKEWNQQYTDYQSKEKTSQVNHPWRGGMVSQFARLNAILKIDVIEQQLEGITELILIPHRDLHRFPIHALFSRDFVVSYLPSAAVGLSLQHRFSGISRLSPSLDPPKSPLRRGTLNESVPPSENTLNTLVPPFLRGARGDQSLENPAEIFDLPPSSDPPKSPLRRGTLNEQIPPLTSETLNTPVPPLARGARGVLSILSIENPHSTITDKNGQPKRLAPLPAAEIESEIICRMFDNSTRLEEDAATLDEVETLLQQPHNIFHFTGHGSYNFDTPLESTLYLSNTHRLTVREIIKHDLSNYQLICLPACETALTDKQTILAEYVGLTSGFMRAGVGCVVSTLWPIESGASTLLMIYFYQRWREAGDSLPVALANAQKWLREATREDLATWYQGEIDKISANSPQLSEDEFMLIDSFETDQLTLATMELDQPYQHPYYWAAFTITGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYX6</accession>
    <name>A0A2G4EYX6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_014505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54719">
        <property type="protein sequence ID" value="PHX54719"/>
        <property type="gene ID" value="CP500_014505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="381"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="469"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="488"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="504"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="521" mass="56841" checksum="F0B8C025951D7EED" modified="2018-01-31" version="1">MNLAPTALQQGKYTINATLGIGGFGITYRATHSHLNQTVVLKTLNESLRQHPESAQFQQQFIAEAQRLSRCQHSNIVRVIDFFTEAGQSFIAMDYIPGETLAKIVSPSQPLPEAQALHYIQQIASAVSTIHKSGLLHRDIKPENMIRRSDTHIVMLIDFGIARDFTASTKQTHTNLLSPGYAPIEQYLYDSKCTPATDVYSIAATLYYLLSGQPPIAAPLRDRIPLKDLRQWQPNLSPGVEQAILWGLETDPEKRPQTVENWLASVQETEQLPARKTKQTMRLPAPPPPQLTLLAFVVTSVIAGWMGFDLASRYNSTNLTSNNPETQSLPSLEDLLKSRDLSGPMFGQPSVESSPVPPSELDNLPKSTSDSSIPEPINSPEVNSQPSPSPSPETPTPKPQPEPSETPTPEPQPEPSETPTPEPQTQIAPSPTIAPAPVPEVEPLPSEPPRKFSPPYAPPLVKSAETFSPPEPEPSPVTLPDRSPIDPIPSRSDSNSDSPIVPDSPPTVAEPTVPFPEPAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYZ6</accession>
    <name>A0A2G4EYZ6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54755">
        <property type="protein sequence ID" value="PHX54755"/>
        <property type="gene ID" value="CP500_014325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="878"/>
            <end position="1185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1186" mass="136046" checksum="D1E68B589649366E" modified="2018-01-31" version="1">MNDQRTQAYLNLINQLLSCNKGDEPRILQENEELLDQGLREEMIVVAQQLEEAGKENEVRSLMSIARQLAQALGLLDNNPTESKSTPQDYVNFLMETLQKVSENDNPEVIYPFWAQNLDKLDENLIQVLDEWARNRISSVNTEEATSIAGVIVNISNLIQQFPLGDIGINKELAITGYKIALIIFTFECFPEYWAMTQNNLASVYSDRIRGNKADNLEIAITYYQEALKVYTFDAFPEDWAMIQNNLAVAYSDRIRGNKTKNLEQAISSYCKALKVYTFECFPEDWAMTQNNLASAYLYRIRGNKADNLENAITYYQEALKIRTFDNFPVHWAETQNNLGTVYSERIRGDKADNLEMAITCYHNALKVRTFDAFPVHWAETQNNIAIAYRNRIRGDKAENSDQAITCYEEALKVYTFDAFPQDWAEMQNNLATAYCNRIRGDKADNLEMAITLYTEALKVRKFKAFPQDWAMTQNDLANAYLYRIRGDKADNLEMAIALYIEALKVRKFKAFPQDWAMTQNDLANAYLYRIRGDKADNLEMAIALYIEALKVRKFKAFPQDWAMTQNNLAAAYQQRIRGDKADNLEKAIASYSNALAIYTKENDPLNCLQTARNLANLHYSEKQWQPATKAYNLAIEAVENARLEALNPHSRQEVLSNAIGVFNRIVKAYLNLNQTEKALEYIERSKGRNLVELMTQKNLQPQGVSQEIIDKLNELKQRAVNEQIRLQHQSINQNLMRSDNLTPYVQDHSYLKEYQQELDIFIEREIKPIDPLFSLTQKVDPIPFTDIQALTDAETCLLQWYITGEKILAFVVSANGDIKVWQSSEDKRKQLFDAAIRNYLQLYYSETGKKEWINQLSSLIQTFADILHINDILALIPDTCKRLIIIPHWFLHILPLHALPISNSHVLKFGAGANAQDLHDLFPNGVQYAPSCQLLRIAQSFHHSDFHKLFAIQNPTKDLLYTDLEVNIVSNFFTDTESQIIAKDNATKNAIISHLKTSNNHCHHFSCHGEFKPNNPLESALLLANKEPLTLGEIFELRLNQCRLVTLSACETGLIDINSISDEYIGLPSGFLFAGSPSVVSSLWTVNDLSTSFLMIKFYEILFSVNLNISVAVALKEAQDWLQNLTIEKLDKFLEQYQPQIDKYLAPLRPGQRKIYQESLEKIRQRQPHPFANPYYWAGFIATGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ13</accession>
    <name>A0A2G4EZ13_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54764">
        <property type="protein sequence ID" value="PHX54764"/>
        <property type="gene ID" value="CP500_014370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="17"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13555" checksum="DF7D3BE1DE3EE3C8" modified="2018-01-31" version="1">MLQTTITIPQTFKVTHEQFQQIAAVNRDLRLERTATGELIVMAPTGSETGNRNLDIEGQLWLWNRQTKPGVAFNSSSGFKLPNGADRSPDASWVKLGCITGICLRFNRCLVVRLNPSLIIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ34</accession>
    <name>A0A2G4EZ34_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_014235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54785">
        <property type="protein sequence ID" value="PHX54785"/>
        <property type="gene ID" value="CP500_014235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="221"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="308" mass="32540" checksum="ED4437F18F31BD87" modified="2018-01-31" version="1">MPLPIAISPAEPILAQNRQTSPQPAIRGDSEQVGIQVYQRALPAFVTINAGGSSGSGSVVRADGLVLTNEHVVRGARQGAVAVVNSNGNRYRGRVLATDVANDLALIQLETNDRFPVIPVAETSGIQVGQRVYAIGSPFGLSGTLTTGILSRIGRNGDLQTDANLNPGNSGGPLLNSQGQLIGVNKAILSPDGRSNSGIGFATSAPVAQRFIQQVIARRSSPETNSSETGSPRRLGVNIDRSNLSIESVERGSVAAVAGLRRGDRLVAVNGSRLRQIDQLLRFLDGGPDTMLLTVERDRQLREVRINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ36</accession>
    <name>A0A2G4EZ36_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_014445</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54738">
        <property type="protein sequence ID" value="PHX54738"/>
        <property type="gene ID" value="CP500_014445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PHYTOCHROME_2" evidence="4">
        <location>
            <begin position="246"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="457"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="418"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="700" mass="78370" checksum="AA9386AB9F2E2BC4" modified="2018-01-31" version="1">MSLKIHQQEQKSPRSSSALSKPKKWSNEECLEECLSLPEMDQQKALIIQMQQQVQLSNLLNQINNEIRSTLDIEQVLTSACRLLGQALNCSRSSILVKEPNSEEILVTRGEYNGGNYPTQLGMKVPIIGNPHLQAIVSQQESLAVTKFIDFPGLNEKSKKIVEALEIKSMLAVATRYQGEVNGVIGLHQCDREREWTDWERQLLEGVGSQLAIAINQAKLYSQTRRLAEQESLLRLIGNQIRSTLDLNTILQTAVREVRQLLQCDRVIIYQFQDNWQGKVVVENMTVPWPSILGDMGADKCFKGDYADFYQQGRVRAINDVFNAGLEPCHVDFLDSLQVKANLIVPIVTSINEENSANTAVSYNPKFLGKLWGLLIAHECGDTRNWEQQETELLSQIADQMAIAIQQAELYSQVQDAAVKSQAQTEQLQATLQELRSTQQQLIQSEKMSGLGQMVAGIAHEINNANNFIHANLFHTQEYVKTLTEAIDLCRKACPGTIDKITEELELDYIREDFPPLLHSMQEGSGRIRSIVTTLRSFSRLDHSEFKAVDLNEGLDSSLFMLQNKLKSNIKIEKQYGSLPLVQCHAGQINQVFYNLMDNALDAIDATEKPGELTLRTFVREPGWVTISIRDTGEGISAETQDKIFDPFFTTKPVGSGTGLGLSVCYQVIVQAHCGRINCVSQVGEGTELIVELPIANHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ37</accession>
    <name>A0A2G4EZ37_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Allantoinase PuuE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54760">
        <property type="protein sequence ID" value="PHX54760"/>
        <property type="gene ID" value="CP500_014350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10977">
        <property type="entry name" value="CE4_PuuE_SpCDA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017625">
        <property type="entry name" value="PuuE/SpCDA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03212">
        <property type="entry name" value="uraD_N-term-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="69"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="301" mass="34524" checksum="DE311543B2945523" modified="2018-01-31" version="1">MSANYPRELIGYGQNPPDPKWPNRARIAVQFVINYEEGGETCILHGDASSETFLSEIVGAVPLSGLRHMNMESCYEYGSRAGFWRLHRMFTSRGIQVTVYGVAMALERHPEAVAAMLAADWEIASHGYRWIDYKYFGEEAEREHLQRAIALHTQVTGSRPLGWYTGRTSPHTRKLVVEEGGFLYDADSYADDLPYWVYECARPHLVIPYTLDNNDMRFATSQGFNSGDQFFAYLRDTFDVLYAEGETAPKMMSVGLHCRLAGRPGRAAALGRFLDYVQQHERVWVCRRIDIARHWHEYHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ43</accession>
    <name>A0A2G4EZ43_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54766">
        <property type="protein sequence ID" value="PHX54766"/>
        <property type="gene ID" value="CP500_014380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8305" checksum="8864C4CCA16703AD" modified="2018-01-31" version="1">MNTLDQVLETALQLSYEQQEMLIKILQNRHRESIRAEIAADAQQTLADFRTGKFRQQSAEDVIATLRQSLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZD0</accession>
    <name>A0A2G4EZD0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="5">IGPD</shortName>
            <ecNumber evidence="5 6">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisB</name>
        <name evidence="7" type="ORF">CP500_013640</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="5 6"/>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54875">
        <property type="protein sequence ID" value="PHX54875"/>
        <property type="gene ID" value="CP500_013640"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="219" mass="23890" checksum="0458FF9C22C99D1C" modified="2018-01-31" version="1">MNDKLQIMEIIDRVSIPPALPVQVARAAFVKRTTLETDVNVSLNLDGSGTCKAATGIPFLDHMLDQIASHGLIDLDVQAIGDLAIDDHHTNEDVGITLGQTLAKAVGDRSGISRFGHFIAPLDEALVEVVLDFSGRPHLSYNLQIPNQRIGTYDTELVKEFFSAVVNHTQMTLHIRQLQGGNSHHIVEATFKAFARALRMAVAIDPRRASRIPSSKGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZJ7</accession>
    <name>A0A2G4EZJ7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_013515</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54932">
        <property type="protein sequence ID" value="PHX54932"/>
        <property type="gene ID" value="CP500_013515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022138">
        <property type="entry name" value="Helicase_SWF/SNF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12419">
        <property type="entry name" value="DUF3670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="658"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="954"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1128" mass="129143" checksum="53837D0F386EC653" modified="2018-01-31" version="1">MKILHGTWIPQPGEEFIQPGAFYLWVETTEQKQFRKPTQRHPRQSAAADLATLLSTELGVKPPLPCQIQDLISPQYFLLPTVNNQPLPSLELSRYLEEELPESFEFQYWQIDCYKTVTSDKIGGFVNNVVSLLDDLHFMALHNLAEIQLGSDLLFWFHYTQALKRIIFKDQYIPALTYRELATPKASSETRRGEGEKGKGGERVSFIHDGREALVEGSGTKRKSAKSTEVATDSSTTTGGRKAKSKKQTAVSQTVDISPKSSNYTIEIYPGWKFIGEEYETTIQQYVEYMPLVCVAGVNKPRETPEFYDRTTLLRHFSESLLVDILTHLPTTQAFEKTIADSLIYDCLHGSGKVAKTSLEQFKQWQSWHDRIDRTQSEQSFHLYFKLQDPAESEAPWELQFQVAPKADPSLRLSLQEYWRMRAAEQKQVQNQMGQGFEQQLLMNLGYAARIYPTLWPGLETDQPIGIGLNLESAFGFLKESAWVLENAGYKVVVPAWYTPQGRKRAKVRLKAKGKSLSVGEDKSKQYFSFDRLVEYEYDLAIGGEPVNEQEWNQLVSAKTPLVQFRGQWLELDQDKMRQMLDFWKTHQQDNPELSLLDFLKLTTEDHEDVELEVDRNSSLAEMLNKLGDKSQLQAIENPQHLQGNLREYQKRGVSWLQYLEQLGLNGCLADDMGLGKTIQVIARLLQEREIATKAGVKNIPPTLLIAPTSVVGNWYHEIQKFAPQLQATIHHGTQRAKESKAFKQACRENDLLITSFALARLDAKLLSEIKWHRIVLDEAQNIKNPKAALTKAILKLNAPHRLAVTGTPIENRLLDLWSIFNFLNPGYLGNQTQFRRNFELPIQKNNDLRQSATLKKLVEPFILRRLKTDQSIIKDLPDKVEQKLFCNLTKEQASLYQAVVKDVETKINELEGIQRKGLILATLTKLKQICNHPMQFLQDGSEFTPERSHKLTRLSEMVEEVLDEGESLLIFTQFTELGQAIEKYLRQACHYKTYYLSGSTSRKKREQMIAEFQDPETEPSVFVLSLKAGGVGITLTKANHVFHFDRWWNPAVEDQATDRAFRIGQQRNVFVHKFVAMGTLEERIDEMLEDKKKLAGAIVGADESWLTELDNEAFKKLIVLNQSTIME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZL1</accession>
    <name>A0A2G4EZL1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-ACP synthase</fullName>
            <ecNumber evidence="4">2.3.1.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_013405</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.41" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54946">
        <property type="protein sequence ID" value="PHX54946"/>
        <property type="gene ID" value="CP500_013405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="3"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="422" mass="44374" checksum="FE4418720983AAF7" modified="2018-01-31" version="1">MDVVVTGIGLVSALGSLENSWKKLLAGESGIEHHQPFLALEPRPLALIDPKPADLITLIRRVLADALLDANLTLPIPDCGIAIGSSRGFQANLEQLLREGSSATDCVTDVTDVTDVTDRRKKEEGTGKKEEGREFLLPHAQLTMRDARCAIPYSEFVNFLPHMGAIAVARAIGSTGPVLAPMAACATGIWSIAQAVDLIQNGQCQRAIAGAVEAPVTPLTLTGFNQMGALATTGCYPFDQDREGLVLGEGGALFVLESADLAMRRGAKIYGKVSGFGLTNDACYANAPEVGGKSAIAAVTQCLKRSNLSAYAIDCIHAHGTATELNDQHEALLIQKLFPFGVAVSSTKGATGHTLGASGALGIAFSLMSIKKQILLPCVGIRKLGFELDFVRCARSTKVRNAVCLSFGFGGQNAAIALTQYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZP5</accession>
    <name>A0A2G4EZP5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54984">
        <property type="protein sequence ID" value="PHX54984"/>
        <property type="gene ID" value="CP500_013255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12889" checksum="A4DCE86776AD93F3" modified="2018-01-31" version="1">METLNYRDLVKQLLTQYLSYQSSEDSIEMEAIFDEERGRYLLLHIGWQDEERIHGCPIHIDIKDDKIWVQRDFTEAGLAEKLVELGVPKNDIVLAFRSPFVRQFTGFAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZU3</accession>
    <name>A0A2G4EZU3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55034">
        <property type="protein sequence ID" value="PHX55034"/>
        <property type="gene ID" value="CP500_012765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="2"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="15771" checksum="212C7298BAE4E70E" modified="2018-01-31" version="1">MKVLIDTNIIVDVALNREPFFAESDRILRFVEEGKIQGYASASTFSDLYYIIRRDKGRDWTLDFLRQLATFCQVAAVDDSIISMALACNFKDFEDAIQYSTAVINRVDAIVTRNPRDFPVTTPSIVTPNQLIQEITNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F023</accession>
    <name>A0A2G4F023_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54787">
        <property type="protein sequence ID" value="PHX54787"/>
        <property type="gene ID" value="CP500_014055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="143" mass="16293" checksum="F1A356181B97BCA5" modified="2018-01-31" version="1">MNAAEQAKNIELTSKIAAVVNLFKSEFPDAKVDLKPWMNDQDTRELVDPDSIDIGFHFPGRSRLLQSRSILIQIRFYQDPVEGDRRAIGVEAAGYDHSGQQWRFSTVENWSFLGKTEPAAESAQKLKHFCQQIFVLFNKSFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F064</accession>
    <name>A0A2G4F064_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55164">
        <property type="protein sequence ID" value="PHX55164"/>
        <property type="gene ID" value="CP500_012335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="17906" checksum="1C5D18983B773B76" modified="2018-01-31" version="1">MTESEIYNVVLFRDASVGAISKLSVAIATTLLSTVVTATQAYAVPVTYDFTITVTKGGLAGNSFNGSFSYDDAKLKGTGVEELGITEGLTTCLNYLGRTYRETDDTSYPTFPTLRFEDGKIAQLNFWIQPNQRVNWWNLPGWEVKLSEPKISDSTVPNCQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F082</accession>
    <name>A0A2G4F082_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase C39 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55165">
        <property type="protein sequence ID" value="PHX55165"/>
        <property type="gene ID" value="CP500_012340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="2">
        <location>
            <begin position="145"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="340" mass="37348" checksum="D4ACB023F595C79A" modified="2018-01-31" version="1">MEILVTLVLGSVLLVWGMRFGRVLVRSGVTANDLFKGRNSIALLFLGFYFALLLLALNLPQMPALPIEWRVHGMRVTWTLLRVMLMGVCGIGFSISWLTARSQVIAVILIGCLGLGGFTGAQAYFLAPIYGDLIDNLQPNGVFRQTSNSSCAPAALATVLRRWGMNATESSVAKEAGTSRLGTSMPQLIIAARALGMQGIELSPTWEQIQQINRPGVLAVWLFDGPRKLPHAVALLGMNDNVAVIGDPARGRIFSLDRATFAKIWREEYVPIFRSADILLSDKQAIEFSTKLGYNSGDLQADIERFQKDKNLKISGKLDRMTELMLRGPFLEGVPRLDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0A2</accession>
    <name>A0A2G4F0A2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DUF202 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_013885</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54867">
        <property type="protein sequence ID" value="PHX54867"/>
        <property type="gene ID" value="CP500_013885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="7">
        <location>
            <begin position="24"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="15865" checksum="AB7CB61427BEFE5B" modified="2018-01-31" version="1">MLLKLKSTKVDTEKTRRPNPSRVRDHLANERTYLAWMRTAISLMGFGIVIVRLRTFHPPLLPTPGNGWKLGLLFSAVGLLTVLFSTKHYFGVRHDIDYDTYEPTDRWVILFSLAIALLGAGVIYYIFTVPSSLEGLMAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0K4</accession>
    <name>A0A2G4F0K4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative regulatory protein CP500_013270</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RemA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54987">
        <property type="protein sequence ID" value="PHX54987"/>
        <property type="gene ID" value="CP500_013270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01503">
        <property type="entry name" value="RemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007169">
        <property type="entry name" value="RemA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38449">
        <property type="entry name" value="PTHR38449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04025">
        <property type="entry name" value="DUF370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="9645" checksum="3C7C122CDFDF9041" modified="2018-01-31" version="1">MDIQLINIGFGNIVSANRVIAIVSPESAPIKRIITDARERGQLVDATYGRRTRAVIITDSSHVILSAIQPETVANRFVVSKDGQNRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0R3</accession>
    <name>A0A2G4F0R3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55364">
        <property type="protein sequence ID" value="PHX55364"/>
        <property type="gene ID" value="CP500_011235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="22055" checksum="E8B1301DE9E40F13" modified="2018-01-31" version="1">MVASQNSGYLSPEEYLQLEEKSSIKHEYRQGDVYAMAGASNTHVLIAGNQYVLLRNHLRGGGCLPYISDTKVRIESIDIYYYPDIAVTCDRRDREFKNFLRYPCLIVEVLSPTTEAFDRGDKFADYRNLETLQEYVLITQTRIQVDVFRRNEFGQWILYPHKAGDTIHLASIDFSCAIEDLYEDVDFSPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0S6</accession>
    <name>A0A2G4F0S6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CRISPR-associated endoribonuclease Cas6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cas6</name>
        <name evidence="6" type="ORF">CP500_011220</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55361">
        <property type="protein sequence ID" value="PHX55361"/>
        <property type="gene ID" value="CP500_011220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019267">
        <property type="entry name" value="CRISPR-assoc_Cas6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010156">
        <property type="entry name" value="CRISPR-assoc_prot_Cas6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045747">
        <property type="entry name" value="CRISPR-assoc_prot_Cas6_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10040">
        <property type="entry name" value="CRISPR_Cas6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01877">
        <property type="entry name" value="cas_cas6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRISPR_Cas6" evidence="5">
        <location>
            <begin position="159"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="278" mass="31193" checksum="E099FC5194B70F5A" modified="2018-01-31" version="1">MPHSLVLNILPLSPISPGYLTGRHIHALFLTLVSSADRNLGNYLHESQIDKSFTLSPLQIQKPSNQKPARYLQWEHDKQIAAETPCWLRISLLDDTLFGQLTQLWLNLNPKDPWHLGPADLLITSIQGTAQSGQPWANACNYQELYDRASDCDRTLSFQFATPVAFRQGKYDMALPTRDALFNSLLHRWNKYSGIEFSDIALDAIFPSFFDISTEIIADSRSKFIGSIGGITYKIMGEVESVKIKQLNALADFALYCGVGRKTTMGMGIVRRLAINKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0S9</accession>
    <name>A0A2G4F0S9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4101 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_011190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55355">
        <property type="protein sequence ID" value="PHX55355"/>
        <property type="gene ID" value="CP500_011190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044685">
        <property type="entry name" value="ARC6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025344">
        <property type="entry name" value="ARC6-like_IMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33925">
        <property type="entry name" value="PTHR33925"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13355">
        <property type="entry name" value="ARC6-like_IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="576"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="6"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="769" mass="85434" checksum="13DCC0ACB3D0584A" modified="2018-01-31" version="1">MLIPLDYYRILGLPIQATAEQLQQAHRDRTLQLPRREYSEVAIVARKQLLDEACALLSDSDGRKAYDASFLVKTYDRESEAGILAKHQRSKTSTGTATVLQDSEETDWQESGVLDATPDPHTPSIEIDDNQFVGALLVLQELGEYELVQKLGRPYLNNGSTGIEEGRFGDKELVGPDIVLTVALSCLELGREQWQQGQYQNAAKSLDAGQELLLRESLFPSVRGEMQTDIYKLRPYNILELLSLPEDQVSERRQGLKILREMLEERGGIDGSGDDRSGLGIEDFLRFVQQLRKHLTSSEQQTLFEAEAGRPSAVATYLSVYTLLAQGFAARQPSMIRRAKLMLMQLGRRQDVHLEKAVCSLLLGQTEEASRALELSSEKEPLAFIRENSQDSPDLLPGLCLYAEHWLQEEVFPHFRDLAKHSVSLKDYFADPKVQAYLEALPLDTETTNEWVVVQPRSGGKPQVRSQLISSLHPSPTDSGRSATVTFTPLAPAQSTPGQSPKYQGTAAAPMPPTSAQGPTPTQIGSTSNEHHRRPPHSSRRSSRNSAGLMGNLVDRAKKLGSQISTQVKSMPRNRLGLLLAAVFLSLFILWLIFSILGNIVQALSGPYLQGEQALVSIEAPPIEIPALPPAPPEPSAPAPESGSITEQTGEQIIQSWLSAKAAALGPNHIVEELKQVLTEPALSRWQLMAAAQQRNNAHQSYKHKLQVTKVTANPTNPDRAEVEAEVNEKAEVFDREQLVTSRNENLRIRYDLIRQDGQWRIMDWQVMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0W3</accession>
    <name>A0A2G4F0W3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55402">
        <property type="protein sequence ID" value="PHX55402"/>
        <property type="gene ID" value="CP500_011045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="120" mass="13499" checksum="A40B665515696FE7" modified="2018-01-31" version="1">MAFSLGKRLKATREALGLTQEQVIEQLELRYGITMSQQAISCIENGKRKVDAERELPAFAAVYEKPIDYFYETLELPVATPPVAPAPKRRSTVTVDMDALTHRDKLELAAELIHNVLQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Y3</accession>
    <name>A0A2G4F0Y3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55413">
        <property type="protein sequence ID" value="PHX55413"/>
        <property type="gene ID" value="CP500_011115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="2">
        <location>
            <begin position="186"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="378" mass="42702" checksum="B82647E03E4335DE" modified="2018-01-31" version="1">MLEKVKLHNFKSHKDTELNFDDSRLHALVGQNSSGKTSVLQALHYLSRLANSSFANIFQYERAPQFITTIGQDNMSVTASGFWRYKDRKDWEASYNWRQQSVNPPWFPTASWNVDRDPGNVQGWSSSLSDARYPIPQSLRYSVHLKLVASNLAKAAYSDAITPRVEFDGSGLAPTLDYLRDEAPDKFQSLQEMLKRIVPGVREVGVKRAKVMINRQRLIEVDGKSISYEESQEMTGQEVVLDMNTGKRIPAHAISEGTMLALGLLTVLMNPNQPNLVLLDDVEQGLHPKAQRELIAVFKEIIQQNNNLQIIFSTHSPYIVDELTPSQVHVLSNNNSGVTHSKRLDEHPDVEWAKQTLTTGEFWDAEGEDWVVAGEIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F115</accession>
    <name>A0A2G4F115_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55450">
        <property type="protein sequence ID" value="PHX55450"/>
        <property type="gene ID" value="CP500_010750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013545373" evidence="1">
        <location>
            <begin position="26"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="15968" checksum="14CF920C35721197" modified="2018-01-31" version="1">MKSRIITTAAILGAIAFLTPHPISAQPATQGGTRPGFWQPGAQIDNTRNLTLILLNETGLNLEYGQSGVGLSSLPIGATKNVMVRVSNRTGDIVNIPINTTGGSTTLKYDYSVDAQKNIVTVRITTSDGRTRQDRSIYIDEKGRVYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1B8</accession>
    <name>A0A2G4F1B8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tryptophanyl-tRNA synthetase</fullName>
            <shortName evidence="8">TrpRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">trpS</name>
        <name evidence="10" type="ORF">CP500_010185</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tryptophan to tRNA(Trp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55545">
        <property type="protein sequence ID" value="PHX55545"/>
        <property type="gene ID" value="CP500_010185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="199"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="19"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="147"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="199"/>
            <end position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="336" mass="37567" checksum="E52DE442C72017C6" modified="2018-01-31" version="1">MVKQRVLSGVQPTGNMHLGNYLGAIRNWVEGQNQYENYFCVVDLHAITAPHNPATLASDTYTIAALYLACGIDLEHSTIFVQSHVSAHTELAWLLNCITPINWLEDMIQFKEKAVKQGENVNAGLLNYPVLMAADILLYDADKVPVGEDQKQHLELTRDLVNRLNHQFGTPENPVLKLPEPLILTDGARVMSLTDGTRKMSKSDPSELSRINMLDSPDTIAKKIKRCKTDALRGLTFDDRDRPEARNLLTLYLLLSGKSKEEVAAECENMGWGDFKPLLTETTINALKPIQDKYAEIMGDRGYLESVLRRGKEQAEAIANQTLTKVKKAFGYSLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1G0</accession>
    <name>A0A2G4F1G0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TerB family tellurite resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55307">
        <property type="protein sequence ID" value="PHX55307"/>
        <property type="gene ID" value="CP500_011420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="157" mass="17687" checksum="C8EEB678858B47C0" modified="2018-01-31" version="1">MQTPPPPSITPRQMNLLRIVAYMAWADGELATEEVNLMLNRFCSLFVADVDGQQLQQELRDYVMQNIPLDELIHQLESQEEKELVLQLGYEVIASSSRTPDEPKINAEEAAAYQKLVQLLNLPEDAVKRIEAEASASPTSEGIVEKMAHKLEHFIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1K8</accession>
    <name>A0A2G4F1K8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55651">
        <property type="protein sequence ID" value="PHX55651"/>
        <property type="gene ID" value="CP500_009575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="8376" checksum="BBC085787EF8A9B1" modified="2018-01-31" version="1">MTTVRQPLLSCTECDLGYLSCFGRSRRFLTVAIDRNLRLNLIILRVLLHRNLCKVLSFQNLLKFGLRHQMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1N9</accession>
    <name>A0A2G4F1N9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55387">
        <property type="protein sequence ID" value="PHX55387"/>
        <property type="gene ID" value="CP500_010965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7906" checksum="9F8539D1597C8A98" modified="2018-01-31" version="1">MSDRNIALINRFAPDRVTPAIRRSSDTITLDNLLLYIYAFLNSFRDGIAGSYCSTVRSHTYHSHFTQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1R0</accession>
    <name>A0A2G4F1R0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55700">
        <property type="protein sequence ID" value="PHX55700"/>
        <property type="gene ID" value="CP500_009395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10220" checksum="F7EBEE66BA7714C5" modified="2018-01-31" version="1">MIYLLIKTIQPILVPLCLVSAWGLMFLLFSSIGATVTDSLRRAQRMHQIPCANCVFFSGDYHLKCPVQPTIALSEDAIDCPDYRSNSRTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1R4</accession>
    <name>A0A2G4F1R4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA (Adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tsaB</name>
        <name evidence="2" type="ORF">CP500_009350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55692">
        <property type="protein sequence ID" value="PHX55692"/>
        <property type="gene ID" value="CP500_009350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TsaD" evidence="1">
        <location>
            <begin position="63"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="240" mass="26591" checksum="B560BF41434A0B57" modified="2018-01-31" version="1">MNSNPKDTTSVKKYGLALHTASRELGLAISNFDGDSRCETWYLDRDLATHLHQYLIDFIQPQTWADLAFIAVAKGPGGFTGTRIGMVTARTLAQQLNIPIFAISTLAAFAWAQPAQSPLAKVDILELEPPQPPLTKGGLLRDDIALQMPAQRDQLFGAVYSVNNNSGLTKLFPDTVMTPESWQEKLKNWQNSYQLIEVGNELGSSVSSVLELAYLEWQIGSRPDWSDAFPYYGQHPVKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1S7</accession>
    <name>A0A2G4F1S7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55723">
        <property type="protein sequence ID" value="PHX55723"/>
        <property type="gene ID" value="CP500_009420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="34430" checksum="B73FA2957D7BEA1D" modified="2018-01-31" version="1">MTTITLGKNGPAVIPLCVGTWAWGDKLFWNYGSNYGAAEVETAFKTSLDSGVNFFDTAEVYGNGLSEELLGQFIKKTSQPVQIATKFGPVPWRITGKSVTEALNASLKRLQVEQIALYQVHWPFSFLLSQETLMNALADAVKQGKIEAVGVSNYSEEQMREAHKILAARGVPLATNQVRYSLLSRQVEKQGIVSAARELGVTILAYSPLAQGLLTGKYTAQEQPAGARKFDARFSKTGIEKIELVMSTLRKMGKKRDRTPAQVALNWLIAQNGVIPIPGAKTAKQAQENAGALGWTLSQDEVNQLELMTRPWLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Y3</accession>
    <name>A0A2G4F1Y3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein PatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_009010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Controls heterocyst pattern formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell septum</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="1">By nitrogen starvation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55770">
        <property type="protein sequence ID" value="PHX55770"/>
        <property type="gene ID" value="CP500_009010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043158">
        <property type="term" value="P:heterocyst differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025497">
        <property type="entry name" value="DUF4388"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024186">
        <property type="entry name" value="Sig_transdc_resp-reg_PatA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14332">
        <property type="entry name" value="DUF4388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005897">
        <property type="entry name" value="RR_PatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="1" id="KW-0364">Heterocyst</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="271"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR005897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="405" mass="45191" checksum="00A6E76637263273" modified="2018-01-31" version="1">MQGNLSEIDIRSILQLIELGQRTGELFVEAYSSNGSGTGTQPSPRSQAGGQSWYVFCFNGQIIYATQSAGSLFRLRDYLRRYKAEKTLDKIEVPYMASTNAPEYGYLWVLLEKHILTPAQGRTIIHSMIHETLFDLLSLHQGSFTFEMGSALAPQLTSLEISSLLAKIVKQVQQWKQFHPHIQSPNQCPVISDAAELQVALPVNTFNTLKLWADGRTSIRQMARYLNRDVLTVAKAIYPFVQQGLVQVFFESVTPANNKKDLYLPKTKVPRVVCIDDDNVIRKTVESILNEHGYEVTGISSPLEALSLVFKLKPDLILCDIAMPELDGHEICAMLRSSSAFRQTPIVMLTGIEGFIDRVQARMAGATEYITKPFGESELLMLVEKYVGPGYPPAIGDTLSVKKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F201</accession>
    <name>A0A2G4F201_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55768">
        <property type="protein sequence ID" value="PHX55768"/>
        <property type="gene ID" value="CP500_008985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="7178" checksum="294F4C0F75289E2F" modified="2018-01-31" version="1">MWWYFILLNREGAKDAKEEGRRKKEEGRRKMQFMFDRALGFGGRLICGVYKRAIEVIYGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F222</accession>
    <name>A0A2G4F222_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Urea ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">urtA</name>
        <name evidence="3" type="ORF">CP500_008915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55810">
        <property type="protein sequence ID" value="PHX55810"/>
        <property type="gene ID" value="CP500_008915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06355">
        <property type="entry name" value="PBP1_FmdD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017777">
        <property type="entry name" value="ABC_urea-bd_UrtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000709">
        <property type="entry name" value="Leu_Ile_Val-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00337">
        <property type="entry name" value="LEUILEVALBP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03407">
        <property type="entry name" value="urea_ABC_UrtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013686777" evidence="2">
        <location>
            <begin position="27"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="443" mass="48111" checksum="DE42FA9DDF604477" modified="2018-01-31" version="1">MAKRFDRRKFLFYSSATLTSSLFLKACRTPTPTASPEASASPTTTAASPASPASSGNTIKVGILHSLSGTMSISEKSVVDAEQLAIEEINKAGGVLGKQIEAIVEDGNSDWPTFAEKAKKLIDQDKVVTVFGCWTSASRKAVLPVFETKNHMLWYPVQYEGQECSKNIFYTGAAPNQQIEPAVDWLLENKGKKFFLVGSDYVFPRTANTIIKAQLAAKGGEVVGEDYIPLGGTEVTPIITKIKAALPDGGVIFNSLNGDSNVAFFKQLQGAGLGPDKYPSMSVSIAEEEVKAIGVEYLKGHYAAWNYFMTVDSPANTKFVEAFKAKYGKDRVTNDPMEAAYIMVYLWKQAVEKAGTADDLDKVRAAALGQTFDAPEGKVTMETNHHISKFVRLGEVGEDGLFKIAFATPEAVKPQPWNQFVEETKGFSCDWSDPAKGGKFKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F277</accession>
    <name>A0A2G4F277_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS5/IS1182 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55848">
        <property type="protein sequence ID" value="PHX55848"/>
        <property type="gene ID" value="CP500_008820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13586">
        <property type="entry name" value="DDE_Tnp_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="6"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="12017" checksum="143BC7A5ED83737C" modified="2018-01-31" version="1">MPKTTILLDNGYHPEKLTQALEEIYPQIMTKIQFELSAKPSKAEKQAKGQSGFVPVAARWVIERSNAWVERCKSLVKNFDRTLARSNAKLKLCFIRLMLKRLAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2E5</accession>
    <name>A0A2G4F2E5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55944">
        <property type="protein sequence ID" value="PHX55944"/>
        <property type="gene ID" value="CP500_008205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="4"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="386" mass="42539" checksum="71A56F2E61BFFF3D" modified="2018-01-31" version="1">MHDLKVVIIGAGIGGLTAGIALQQAGYEVEIYDRVKELRPAGAGISLWSNGVKVLNRLGLGENMAKIGGQMERMEYRTKTGELLNDIDLMPLIEQVGQRPYPVARRDLQHMLLAAFKGEVKLDRKCIAVEEDATKVTAIFENGDKAQGDLLVAADGVRSILRTYVLGHEVEPKYGGYINWNGLVPAAEELAPKNTWAIYVGEHKRASLMPVAGDRFYFFLDVPLPKGTPANPDNYKAELKQYFKDWAEPVQLLIDRLDPAAVARPEIHDVGPIDRFVRGKVALLGDSAHATCPDLGQGGCQAMEDGLVLTNYLLSTNLGVEYALKRYETERKQRANAVVEKARQRAEQIHGKDPVVTEKWYAQLAYEKPTDVTDAIAKVISAGPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2G8</accession>
    <name>A0A2G4F2G8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_008150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55935">
        <property type="protein sequence ID" value="PHX55935"/>
        <property type="gene ID" value="CP500_008150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041033">
        <property type="entry name" value="Prealbumin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17802">
        <property type="entry name" value="SpaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SpaA" evidence="3">
        <location>
            <begin position="76"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="2">
        <location>
            <begin position="608"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="894" mass="95081" checksum="C69D0B5213BB93EE" modified="2018-01-31" version="1">MTDLTNEELIAQQIRPIEVGNAGLAILGIKFNDLGGGADGRPDGIRQPGEPGLRDIPILLEPAATANGVFNPNSGEAEAKSDANGAFSFINLAPGNYRLTETVIPTGFRATTPNPLNATVVDRNVNVLFGNTGTAQGKIVGCKYLDVDGDGFRDGDEPGIKNVRIYLDGSNTDGTTTVPNGTFEPGERSTLTDKNGQWSFDVAPGTYRVREVSETRVDLLGGLDKNNQYPQTLKDDFPQTTPPNNVPLLDVTVAAGETFACAQVGDTQLYKIVVNKFQDLDRNGRRNTVGTPLQLEPAVSLVPFILDENKNGKFDSGEEIRFTDGNGVATFEDLRAGNYPVLEIFNATLPKSLLSPAELSLLALRPELAIAGNTTDFKPGNLNLPVPTTPNPLVVSAPGPLATPQSTISRNEPFLVADTYTLKAQDPKFIDLNGDGFQQLPGEVSIPQTGVRPIFTNTPVPFPALSPSPSVVFSPIAPNNTVAGNTGVGNTRPNINVFKYEDLNANGRYDPRLLPNNGINPTGNGERVLGGVQVFIDLNNNGVPEANEPTRTTDPNTGRAVFQNLTPGNYTVREIPGNLLPSTPAAVTFALNTEDANVTFANTPKSKITGCKFEDINQNGYRDGNEPPISGITVYLDANNNGIRDTGELNTTTDKFGTFKFDNLSPGTYSLREDTLSVPSNFKQTTQPLEIVLGPNQTFTCALIGNTRLYDLAVPKFQDDNRDGIQNGNEQSLNGIPFALDSNKNGAYDVGEPLARTGADGAPGKALFKDLLPGTYSVLEVFNNPIVPNPFPIRTGPNPVSFDVPGPDAVPSPVRPVAARTAAGLDHLTEGGLDATVNGTIIDTSLIVAGENAGISFVDDTSFISTANPLTFVLPEDQNYLLFGAPATSSPTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2K2</accession>
    <name>A0A2G4F2K2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56003">
        <property type="protein sequence ID" value="PHX56003"/>
        <property type="gene ID" value="CP500_007555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="115"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="232" mass="26349" checksum="7807F787F60B6E8E" modified="2018-01-31" version="1">MSDGANREQWIGDACAGFASTKPANINYYRLILETLWPPGHSIPGPVVPLSHLCQVINSFRGEPYADTPRRIRELQGEEGFLGIVRFGSGSKTRYQLLSIEISPKREQRIKLSEAFWQKILIKYQYRCAVCGREPPLIRLDRDHKIPRLRGGGNQEDNWQPLCAECNNFKSTACRGCQLECTQCAWAFPESFSPIKISASDIQRIKALAIQQEINSEALLRQIIESYFNSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2K6</accession>
    <name>A0A2G4F2K6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF563 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_007995</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55975">
        <property type="protein sequence ID" value="PHX55975"/>
        <property type="gene ID" value="CP500_007995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="395" mass="45784" checksum="A9EFBC15E0501F10" modified="2018-01-31" version="1">MANSLISNFQRGYLRDLASKVYNKLKYLIKVYLLFKPYARGVIQLSIDNADRYFGNDPDIKIHKLVTQESIEIPPPKFLGCDFLEIITPFKNEVESVMIDARKPGFAFANNHIITPELKVIYEKDIQFEQLPVYREEISADYQKIPGTMAYLSNTMPQNYGHWFIYTLPMLEIYWKFIDRQEIDYYYIGGSLVNFQRETLVALGIPEEKVVTFPSKPDRAITCVIDRKIQNNGHKYPTIFGYRFARNLFLPKDNYANTKYPKRLYVKRGKVDHREVINDNEVIEYLESIGFESLTMQGRTIQEQADIYYNADAIVSVCGSALTNLLFIREKITVIEIFPFGYLDGFFYALSSYAQANYLYLIGEEIPNNPSAPHFSNLKVNINKLKQICKLAGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2N4</accession>
    <name>A0A2G4F2N4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_007580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56008">
        <property type="protein sequence ID" value="PHX56008"/>
        <property type="gene ID" value="CP500_007580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="451"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="672" mass="73851" checksum="7EE1153D493DA169" modified="2018-01-31" version="1">MNTISPYGSWKSPITSDLIVSGTVGLGQVAIDGDDIYWVEGRPSEAGRSVIVRRTPDGTISDVTPPPFNVRTRVHEYGGASFAVARGVVYFSHFADQRIYCQALDSHPEPLTPAVNCRYADGIVDRERNRLICVREDHTEEGESVNTIVSINLADGEDIRILTEGNDFYASPRLSPDGSRLCWISWNHPNMPWDGTELWVAAINADGSLGEKQLVSGGLEESIFQPEWSPDGVLYFVSDKSNWWNIYRTPLNPQRGEAGTPLNPPLARGEAGTPLNPPLVRGEAGIEPLCEMAAEFGVPQWVFGMSTYAVVSESKIVCTYNQQGKWYLATVNLVTKQLTEIETPYTDISSVKAGGERVVFLASSPTESSAIVELNLATSQLDVLRRSTNLTIDRGYLSIPTAIAFPTEHGLTAFGFFYPPQNQDFTAPATEKPPLVVKSHGGPTAATSSSMSLKIQYWTSRGFAVLDVNYGGSTGYGREYRKRLQDSWGIVDVDDCANGAKYLADSGLVDGNRMAIAGGSAGGYTTLCALTFRDVFKAGASYYGVSDLEALATDTHKFESRYLDGLIGAYPERKDLYIARSPIHFTERLSCPVIFFQGLEDRVVPPNQAEMMVEALKAKGLPVAYVAYEGEQHGFRRAENIKRTLDGEFYFYSRVFEFELAELVEEVPIANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2T0</accession>
    <name>A0A2G4F2T0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55767">
        <property type="protein sequence ID" value="PHX55767"/>
        <property type="gene ID" value="CP500_008980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="407" mass="43427" checksum="63F1028D63B84A52" modified="2018-01-31" version="1">MDAEELLERYAKGERKFHSAMLRGVDLKGADLSGIDLSSANLTAAELNEANLTKATLNGTNLTKAFLKGANLSGLVAASSANFTDADLCGANLSKANLSKANFSNANLNEANLSDAQLTSVDFTEASLIEVCLSRAKLNSANLTKANLTEADLSRADLTSITIKDTNLQGAKLRGVDLSKEDLSGANLAEADLAGADLTKINLRNACLQGANLERTGLQGANLMRANLEGAKLKRADLTDANTYGMNIKDADFTGTIMPDGEFYQPETNQQESQKVISMTRKIIRTDKAPAPVGPYNQAIAASGTMLFVAGQIAIDIRLNDIVYTDDVTKQTEQVMANLEAILTEAGATWLDVVKTTVFLKDMNDFAAVNAVYAKYFDAETAPARACVEVSRLPKDVLVEIDCIAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2T5</accession>
    <name>A0A2G4F2T5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phycocyanin subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_007465</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cellular thylakoid membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56062">
        <property type="protein sequence ID" value="PHX56062"/>
        <property type="gene ID" value="CP500_007465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006247">
        <property type="entry name" value="Phycocyanin_b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000081">
        <property type="entry name" value="Phycocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01339">
        <property type="entry name" value="phycocy_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="4 5" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="3 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="18213" checksum="4FE9743B54CD2F36" modified="2018-01-31" version="1">MFDAFTKVVSQADARGEFLATGQLDALSQMVAESNKRMDTVNRITSNASSIVANAARSLFAEQPQLIAPGGNAYTSRRMAACLRDMEIILRYVTYAIFAGDASVLDDRCLNGLRETYLALGTPGASVAIGVQKMKEAALAIASDPNGITRGDCNSLMSEVGSYFDRAASAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Z1</accession>
    <name>A0A2G4F2Z1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ppk1</name>
        <name evidence="6" type="synonym">ppk</name>
        <name evidence="12" type="ORF">CP500_007380</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56119">
        <property type="protein sequence ID" value="PHX56119"/>
        <property type="gene ID" value="CP500_007380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="PTHR30218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015589">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="SSF140356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PP_kinase_N" evidence="9">
        <location>
            <begin position="23"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase" evidence="8">
        <location>
            <begin position="137"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C_1" evidence="11">
        <location>
            <begin position="366"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C" evidence="10">
        <location>
            <begin position="539"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphohistidine intermediate" evidence="6">
        <location>
            <position position="471"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="606"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="634"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX56119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="726" mass="82275" checksum="D66ED7FB7002CE15" modified="2018-01-31" version="1">MSKQKKTPAKTYTEINLSDPQYYFNREQSWLEFNNRVLHEALDPRTPLLERLKFLAIFSSNLDEYFMVRVAALKQQVEAQVSKLTSDGSTPQQQLDAISKRLLPMVSQQHSYFEQTVRPKLAASGIHILDYIDLNQEQRTYLHRYFKEQVFPVLTPLAVDPSHPFPYLSNLSLNLAVVVRDPDTQEELFARIKVPQVLPRFLVLPTDLQWQQKGKSPVWTGVPLEQVIAHNLEALFPGMDIQEYHPFRITRNADLTVEEDEADDLLLAIEQELRKRRFGGSAVRMEIQAIMPPALRDMLMDELVLGEQDVYVVEGLLGLKDLMSFVGLPVPELKDAPWTPVVPPRLRNLEAGRSDESIAHAEESEDIFAAIRRGDIMLHHPYHSFAATVQRFITEAAHDRSVLAIKMTLYRTSGDSPIVSALIQAAENGIQVAVLVELKARFDEENNINWARKLEQAGVHVVYGLVGLKTHTKILMAVRREDGCIRRYVHIGTGNYNPKTAGLYTDVGLLSCREDLGSDLTDLFNYLTGYSRQVSYRNLLVAPVNMRDRFLALIRREAEFCRLNAETGNGSCGRIVAKMNSLVDPQIIVALYEASQAGVKIDLIIRGICCLRPGVEGVSENIKVISIIGRFLEHSRMFYFFNGGDEEVYIGSADWMQRNLTRRVEAIVQVEDPTIAMELQEILGVMLADNRQAWDLQSGGDYSQRRPPANCPEVSSQQILMDMVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F389</accession>
    <name>A0A2G4F389_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA phosphorothioation-associated methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56230">
        <property type="protein sequence ID" value="PHX56230"/>
        <property type="gene ID" value="CP500_006615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024019">
        <property type="entry name" value="CHP04096"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04096">
        <property type="entry name" value="dnd_rel_methyl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="736"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="766" mass="86938" checksum="BF80E4ACD7B5F883" modified="2018-01-31" version="1">MTYDPDITTISEGEPLENNGQLLTPLMVFAAEVLLYEKEAEPLDLRDQAEHGNEEIAVDNLVKKVADCCRESKVGKKLPTAFYIHVSALATLNPVLTIYEKCARQNIENIEEATLVKFQLHQPKISYLFYPDFDTDAHPALQRSIQINLETGEVKCFDYSHSENPPVLHRKETFVTADYPQYQKFSKLTRSEEKWGLLDNTSVIGTREGWLKYLGYCGVEIQDHTVVEICQQGNSELSMPKIERHKAAMLRNSLSKPVRLVLEADLFVDGMTFFDYGCGYGGDIQHIAQEGYAAAGWDPYYQPDSPQINADIVNIGYVINVIESLGERREALLNAWGLTKKLLVVAAQVLIDDSERGQIAYGDGVITSRNTFQKYYEQEELKIYIDQVLSVDAIPVALGIYFVFRDAAEGQSFRASRFRSHLLTPRVRSQVKRFEDYAEMLAPLMAFVSDRGRLPVKGELAEEVAIKGEFHSFNRAWRVILQATDADDWETIADKRRQDLLVYLALNGLEENRPSMRQLPAQIRNDIKGLFDNYQKACTLADLMLYSLGKTEIIGDCCEDSAIGYKLPGSLSVHVSALEELDPLLRLYEGCANRTIGRLDGATIIKFYANQPKISYLFYPDFDTNPHPVLQTSMHINLRDFSVGYQDYSHLSNPPILVRKEAFVAVSYPHYQKFAKLSRQEEKLGILDKWGGFKYREWVKCLEENCVRIKGHRLFWRSDADPEKLKILQTTASERQQKKIEVNGGKIEGTAEGTESTEDGKEEGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3E9</accession>
    <name>A0A2G4F3E9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56268">
        <property type="protein sequence ID" value="PHX56268"/>
        <property type="gene ID" value="CP500_006280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7407" checksum="9F7C777EA915ABCA" modified="2018-01-31" version="1">MLKTLWATVRQGKIELLELSELPEGAKVLVTLLPDEESEFWLQASQTSLDTVWDNSEDDVYAQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3K5</accession>
    <name>A0A2G4F3K5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56301">
        <property type="protein sequence ID" value="PHX56301"/>
        <property type="gene ID" value="CP500_006100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8310" checksum="0E17B23F0E0C1F59" modified="2018-01-31" version="1">MPVNWREHIVSTPDVLRGKPRIKGTRIPVGLILGYLASNNTVEQIIDEFPDIVKEQIAACLDYARDLSDFETVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3N6</accession>
    <name>A0A2G4F3N6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56369">
        <property type="protein sequence ID" value="PHX56369"/>
        <property type="gene ID" value="CP500_005870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="15"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="29230" checksum="A6BFFFEFAC4BF1FB" modified="2018-01-31" version="1">MFVTAELATSQDIPKRVIFPTGDLYSDEPPLETELHLRQIILLLQCLDWLWRDRNDFYVAGNLTIYYSQNQRKSEDFRGPDFFVVHGTDRKPRKSWVVWEEEGKYPNVIVEMLSPTTANTDREFKKKLYQDIFRTPDYFWFDPYTLEFAGFHLVDGEYQPLPENSSGHLWSQQLNLFLGIHQKKLRFFTASGELVPTPEESADFERQQKELAQQREDSERQQKEFAQQRADRLAAKLRELNIDPDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3W8</accession>
    <name>A0A2G4F3W8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arginine decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_006815</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Orn/Lys/Arg decarboxylase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56177">
        <property type="protein sequence ID" value="PHX56177"/>
        <property type="gene ID" value="CP500_006815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00615">
        <property type="entry name" value="Orn_deC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000310">
        <property type="entry name" value="Orn/Lys/Arg_deCO2ase_major_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008286">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036633">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01276">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03711">
        <property type="entry name" value="OKR_DC_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55904">
        <property type="entry name" value="SSF55904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00703">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OKR_DC_1" evidence="4">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="511" mass="54485" checksum="543B3D324317A54A" modified="2018-01-31" version="1">MNCQTKTPLLDALRDRTNQPHSPFYAPGHKGGQGISQPLADLFGAAVFRSDLPELPELDNLFNPEGVIAEAQNLAAEAFGAEHTRFLANGSTCGIMAAIVATCGPGDKIILPRNIHQSAISGLILSGAIPIFVNPEYNPDWDIANCITPESAAAALKQHPDAKAVMVVYPTYHGVCGDLRAIAKITHQYNIPLLVDEAHGAHFNFHPNLPESALSAGADLSVQSIHKTLAAMTQASMLHVKGSRVDIQKLNRALQLVQSTSPSYILLASLDAARQQIALHGAQLMTQTLLLAEKARSQLSQIPGLSVLEPLNTPGFVDLDRTRLTVKVSDLGITGFAADEILHSQLGVTAELPMPQHLTFIISLGNTESDIDNLVKGFQNLTLCGTGILPVLEKGGQDAQPLLPTRKFTLCGTGILPVLENGAISQLGFPTPPLSPREAFFSPMETVAADKAVDRISTELICPYPPGIPALMPGEIITQTAVDYLQQILGDGGKITGCSDPHIQTLKVVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F422</accession>
    <name>A0A2G4F422_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">pstC</name>
        <name evidence="12" type="ORF">CP500_005190</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56485">
        <property type="protein sequence ID" value="PHX56485"/>
        <property type="gene ID" value="CP500_005190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="94"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX56485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="333" mass="35857" checksum="FABD661EC8BD653D" modified="2018-01-31" version="1">MTNFAKQPEKFTNQQTANSTEVDLTDTKGEGLWLESGFTIFVWAFAIGTAGTLFWMSAIIFKDAWPAIHQFGLSFLWNPKWDIHESQFGALPFIYGTVISSAIAIIIALPLGLSVAIVTSENFLPAWVRSPLGFMVELISAIPSVIVGLWGIFVLIPFLLPLQQSLFNNFSWFPLFSSEPLGPGMLPAGILLSVMILPTVAAISRDVLMSVPVDLRSASMSLGATRWETIFKLLLPAASSGIIGATILALGRALGETMAVTMVIGNSIQINPSILAPAYSIPAVLASQFREAQEPLHVGSLMYLALILFVITLLVNAVAVLLVQLIGVKGAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F433</accession>
    <name>A0A2G4F433_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4112 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56543">
        <property type="protein sequence ID" value="PHX56543"/>
        <property type="gene ID" value="CP500_004650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025187">
        <property type="entry name" value="DUF4112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519">
        <property type="entry name" value="PTHR35519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13430">
        <property type="entry name" value="DUF4112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="171" mass="18200" checksum="1151465D7B146C9B" modified="2018-01-31" version="1">MSRSPIQNSPANTPNQSHVASLRRLRRISHLLDNAIPIPGTKYRIGLDPILGLIPGGGDLIGSVFAGYVVFKSAQMGVPQETLVKMATNIVFDTLAGTVPVAGDLLDVAWKANVKNIELLDAHLGSPEPVGKKADWLFVVALLLGLMLIVGGVIFLSVMFFGWVFKALTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F447</accession>
    <name>A0A2G4F447_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56257">
        <property type="protein sequence ID" value="PHX56257"/>
        <property type="gene ID" value="CP500_006210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="149" mass="17310" checksum="6C582CC45B9A92C8" modified="2018-01-31" version="1">MKPIRSLEDALNRCQAMGMRLSRQRRFILELLWQTQEHLSAREIYDRLNQQSLWIGHTSVYQNLEALSREGIIECLERSEGRLYGNVSDSHSHVNCLDTAQILDVHVELPKDLIAQIEQQTGVRIVDYRIDFYGYRSPESTTEGSIAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4C0</accession>
    <name>A0A2G4F4C0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56588">
        <property type="protein sequence ID" value="PHX56588"/>
        <property type="gene ID" value="CP500_004845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="414" mass="45076" checksum="3C1B268991CF94C0" modified="2018-01-31" version="1">MNPSPNRSSKSPKSTSTRKARPSEPAVNPSKDPVSVPETPDESLVASALATPVDENQPPTPTDTPASKDTLQRPLYSSAPKEKTKPKDSPSEPPALSDPAVPSASATNTPVLPVAAPVTADAVTQESQATDDLPAVMRQHPIPPPSEPRQYRAVGLVRGRYTQSEEQFTRGMLMAADGTAIDAVLLGRVMSLVKNHLDLEQEHLWVVYPRTRQEDGNLHAQIMGVWEPETLKKPSEPSSDEESQDTGEIESSGETSSVPLPPSEPDVEDGYFSIRGEVIYQSQDEEKYVIVKIKQAPRKNDENKMKFFKLKLKGDLATKAIGFFWDFHVKLQAETLMIQQANNIGALPIKKRKFPPGEKPGGSRGGGNKRPYTPRPTGDGPRSERPNIKPSAGAPPVPKEPLPKPIKKPKPVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4P1</accession>
    <name>A0A2G4F4P1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase sigma factor, RpoD/SigA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_003635</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56716">
        <property type="protein sequence ID" value="PHX56716"/>
        <property type="gene ID" value="CP500_003635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017848">
        <property type="entry name" value="RNA_pol_sigma_RpoD_cyanobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02997">
        <property type="entry name" value="Sig70-cyanoRpoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="5">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="334" mass="38899" checksum="01A7A979CA568A89" modified="2018-01-31" version="1">MSTTTPKTKTVKADRTSTRSYSSTDTVRTYLHEIGRVPLLTREEEIILGKQVQQMMKLIEAKQALAKEWQRDLTPEEWAAEMELTEAELTRILQIGRRAKKKMIEANLRLVVAIAKKYQKRNMEFLDLIQEGTLGLERGVEKFDPMRGYKFSTYAYWWIRQAITRAIAQHARTIRLPIHITEKLNKIKKVQRELTQQFGRSPTPTEIASVLELHPSQIREYLLMSRHPVSLDLRVGDNQDTELQELLEDETASPENYITSELLRQDLNTLISELTPQQRDVIILRFGLEDGIEMSLAKVGERLTLSRERVRQLEHQALAHLRRRQAQVREYLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4R1</accession>
    <name>A0A2G4F4R1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56729">
        <property type="protein sequence ID" value="PHX56729"/>
        <property type="gene ID" value="CP500_003720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="15997" checksum="1B2E24F980248BC4" modified="2018-01-31" version="1">MNLLQQSRQIIVGLLLVLILSFTTACTTSVSAQKPMSAPVAIGGSRGSYAQLERGNTAAGQDFGQWVTKTANGLVQDAYVRDNNKLGVVITPQVRPTEVKDLAKSLAQGFHKNFPNQDVSVLVYAPDKKLILTAKYDQQSNQIEYKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4U7</accession>
    <name>A0A2G4F4U7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56731">
        <property type="protein sequence ID" value="PHX56731"/>
        <property type="gene ID" value="CP500_003730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="7018" checksum="656D64B95342CA0B" modified="2018-01-31" version="1">MKIFTTHLGLLYNRGYQQAVNDFGITQLLSRIRSYSDEDMDNFQSINPPSILQSPILQSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5C6</accession>
    <name>A0A2G4F5C6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF29 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56960">
        <property type="protein sequence ID" value="PHX56960"/>
        <property type="gene ID" value="CP500_002420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002636">
        <property type="entry name" value="DUF29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34235">
        <property type="entry name" value="PTHR34235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01724">
        <property type="entry name" value="DUF29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="165" mass="19335" checksum="9FA59500895ACB31" modified="2018-01-31" version="1">MTTIQSITTAITSLYEQDFYLWLQTTINLLKEGKFAEIDLENLLEELESMGKSDKNALKSNLRVLLMHLLKYKYQPEKRTNSWIYTIREHRKRIRDTFKTSPSLYRFFEDIFNESYQDARELAADETGLSIATFPPESPFTGEEVLNPDFLPPECDLPENPENIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5R7</accession>
    <name>A0A2G4F5R7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57089">
        <property type="protein sequence ID" value="PHX57089"/>
        <property type="gene ID" value="CP500_002075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9169" checksum="60F5285E8D8C479D" modified="2018-01-31" version="1">MKAIKVMATIDDRGQLCIDEPLKLEQNSRVEVIVLIPEVTEINEDEQSNESILADFRQAWQEAMTGKTIPVAQIWEGIDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Z2</accession>
    <name>A0A2G4F5Z2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57159">
        <property type="protein sequence ID" value="PHX57159"/>
        <property type="gene ID" value="CP500_001830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="169" mass="19615" checksum="F88A59868273EE77" modified="2018-01-31" version="1">MESIDRLLAELRAEYQESQKKSAELKSQRIVQPEPLWQANAVPSNQAIETSGENLHFGGFDQDLAQVKAEYEKQDQAQEIAKQEQLLAEDEAQNKAQEIVKQEQQQVETIVQPQVSVKTHREKVRQAQVWLKNLSKDSDERFWFDQFAFKYSSRIDAAIDYLQAVNEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F632</accession>
    <name>A0A2G4F632_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Magnesium chelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_001370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in chlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57199">
        <property type="protein sequence ID" value="PHX57199"/>
        <property type="gene ID" value="CP500_001370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="213"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="509" mass="55101" checksum="E61B6DDBDB5F4BAD" modified="2018-01-31" version="1">MLARVWSASIVGVDAVKVGVEADVSGGLPKIVVVGLPDSAVQEAKERVRATLKNSGYAFPMRSIVINLTPADLRKEGPSFDLPIAIGILAASEQVSAELLGDHLFLGELSLDGTLRAVAGVLPIAAAAAKMGISGLIVPAGNAQEAALVHGISVYGFENIFAVTDFLNNPHVYSPVKVDGREELAKRRIPGLDLKDVKGQIHARRALEIAAAGGHNLIFVGPPGSGKTMLARRLPGILPPLTFEEALDVTQIHSVAGLLKDKGSLVGDRPFRSPHHSASGPSLVGGGSFPRPGEISLAHRGILFLDELTEFKRDVLEFLRQPLEDGYVTISRTRQSVMFPAQFTLVASTNPCACGYYGDSIQQCTCSPQKREQYWAKLSGPLMDRIDLQVAVNRLKPEEITRQPTGEESEPVRVRVQRARAIATHRFRSESSLRCNAEMQSSHINQWCQLDDASRNLLEMAIRKLGLSARASDRILKVARTIADLSGDESLKTNHVGEAVQYRTIDRMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F660</accession>
    <name>A0A2G4F660_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Deoxyribodipyrimidine photolyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_001250</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57181">
        <property type="protein sequence ID" value="PHX57181"/>
        <property type="gene ID" value="CP500_001250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_7" evidence="4">
        <location>
            <begin position="101"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="284" mass="33077" checksum="676F4241F09B1A2C" modified="2018-01-31" version="1">MTQDMKREFADRQELIAYVRQQFPEAEARDSHVSPTLGGRKAAETALKQVDPAKYTSTRNFLNGAVTRLSPYLRYGVLSLAEVRDIVLAKVLHQEDVVKLINELGWRDYWQRLYAELGNGIWQDQEPYKTGYTASQYSETMPEDIIEGMTGLVCIDSFSRELQETGYLHNHQRMWMAAYLVHWRKVRWQAGARWFLAHLLDGDPASNNLSWQWVASTFSHKAYFFNRENLERYTKAVYCRDCPLYGQCDFEGSYEYLEAKLFPLGEKVDRTGGSKSWNRPKKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F661</accession>
    <name>A0A2G4F661_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57238">
        <property type="protein sequence ID" value="PHX57238"/>
        <property type="gene ID" value="CP500_000940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8042" checksum="A0A2DC1E31BFAC74" modified="2018-01-31" version="1">MTNDGNHKAEAPESPDSKNLDSMAKAFLVSMAWSYAKALEQTKRSENQQQPAPESESESKIEQVDRNSETNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6E1</accession>
    <name>A0A2G4F6E1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57318">
        <property type="protein sequence ID" value="PHX57318"/>
        <property type="gene ID" value="CP500_000620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032721">
        <property type="entry name" value="Toxin-deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14424">
        <property type="entry name" value="Toxin-deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="153" mass="17147" checksum="5E9AB3472BE43EC1" modified="2018-01-31" version="1">MNKEDLQAKKEDLQARAADIRSKYLKRPIGTSNVAIADVYLSNNIAFCVGATSKGGSKSPIPRPLPKSEGGQFEPSVDSRTGRSMDTDAEYKVLSAIADRLELSYDRGVKGNLYLYSELQPCESCNNVLKQFKEKFPNINIDVFWDYPYPRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6K8</accession>
    <name>A0A2G4F6K8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3493 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57379">
        <property type="protein sequence ID" value="PHX57379"/>
        <property type="gene ID" value="CP500_000085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021883">
        <property type="entry name" value="LPA1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11998">
        <property type="entry name" value="DUF3493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11364" checksum="0E9890983C8230E0" modified="2018-01-31" version="1">MPTPNSDDRPYRPKNPRNLSPEQYKRLTAEIAAPYRPLRQVVYVACGASGFIGGLVFLAKIASGNQVSSTLPNFALQVGVVALMVFLFRWEQRAQDQSPKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6L3</accession>
    <name>A0A2G4F6L3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57412">
        <property type="protein sequence ID" value="PHX57412"/>
        <property type="gene ID" value="CP500_000280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="121"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="307" mass="35868" checksum="D8E5B34C73542B7F" modified="2018-01-31" version="1">MVNFLVHKLPEYFQPITIRKKRIISFLLAFILTLISYQVILELITVEIPIFGFHDIVDIQNPQEIPPQRRDFPGDYSQQNLEPFLESLVSHNYWFLSTQELYDYFLASPQKIVPAEYRDRKKVIITFDDGNKSIYTHLLPILEKLENKYGTKNKAVVFINSGFFNTDNSLIKKVNCEELRDGFKKGFYDIQSHGLNHENLTKISLEALDRELAEDQIRLRKCTQDLDPNQTIASHIAYPFGAVNKQVDKYVAKYYKSGYLYNSLKLKLRFFPPNKYRVSRLTVNSKHSAKRLINLASGNWLHKLIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6N2</accession>
    <name>A0A2G4F6N2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplN</name>
        <name evidence="3" type="synonym">rpl14</name>
        <name evidence="6" type="ORF">CP500_001765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57147">
        <property type="protein sequence ID" value="PHX57147"/>
        <property type="gene ID" value="CP500_001765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13298" checksum="11325C3B2CBCF691" modified="2018-01-31" version="1">MIQPQTYLNVADNSGARKIMCIRVLGGGNRHYGGVGDVIIAVVKDAIPNMAVKKSDVVRAVIVRTRKALRRDSGMSIRFDDNAAVIINPEGNPKGTRVFGPIARELREKNFTKIVSLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUJ1</accession>
    <name>A0A2G4EUJ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TIGR01777 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_023000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000257">
        <property type="protein sequence ID" value="PHX53158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53158">
        <property type="protein sequence ID" value="PHX53158"/>
        <property type="gene ID" value="CP500_023000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013549">
        <property type="entry name" value="DUF1731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010099">
        <property type="entry name" value="SDR39U1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08338">
        <property type="entry name" value="DUF1731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01777">
        <property type="entry name" value="yfcH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1731" evidence="3">
        <location>
            <begin position="258"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="308" mass="33004" checksum="A7943FD8E7068CD0" modified="2018-01-31" version="1">MKVAIAGATGFVGSRLVERLHSEGHSVLVFARNSERARRVFPASAYPNLEIVGYTPAESGDWLHSIAGCDGVVNLAGEPIAEERWTAARQQAIVDSRKLTTAKLVEAIANANPKPSVLVSASAIGYYGTSETAEFDENSPAGDDFLAEVCKDWEAAAQPVKNVGTRLAILRLGIVLGMGGALAKMLPPFKLFAGGPIGTGKQWFSWIHRDDVVNLILFALQNPQIEGVLNATAPNPVRMNELCETLGEVLQRPSWLPVPSFALELLLGDGAKVVLEGQQVLPKQTLASGFQYEYPNLKSALEEILSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUP6</accession>
    <name>A0A2G4EUP6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_022420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000227">
        <property type="protein sequence ID" value="PHX53263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53263">
        <property type="protein sequence ID" value="PHX53263"/>
        <property type="gene ID" value="CP500_022420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="630"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="281"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="699" mass="77822" checksum="133A27F29E7A38E5" modified="2018-01-31" version="1">MFLHKLPHMINTFSESIYCPNPTCPQPRNTFGRQHCAACETRLIYRHLWAVGRDVEEVPQGKVIGDRYLAIAPQIWLDSRPDLLPSVPEELPDAIAPYLHLYPQRLHTPEVYGFFQLAEAAQTFDVILLENVPITNFGRLYPSILEAWSKTSAVRQVYWLWQMLQLWTPLTEQGVASSLLVPENLRVDGWRVRLLELHQGNYQPTLRDLGDVWSGLVESAQPQVKSRLGEISQFMRRSSMNIEAIALELNELLLEQAAELPLHLEVVGMTDTGPQRSQNEDTCYPTAADFKISKTSGNDKLIPYLTIVCDGVGGHEGGEVASQLAVLSLKALIQNFLLEIAAQNDLMIPTMVTKQLEEIVRVVNNVISAQNNEQGKELRERMGTTLVMALQLPQKIKVVSEDLRSNNGHELYLVNVGDSRAYWITQNSCQRLTVDDDVASREVQLGHSLHWESQKRPDAGALTQALGTRDGDFLHPIIQRFIVEDEGLLLLCSDGLSDNDWVEQSWESYGPAVLKGEMSLEAAVQYLINVGNEKNGYDNTSVVMTHCRMSPEKLMLFQPTDVPDSIATPMSNSMPKPMSGSVSLKKSLLMPQTQRESQLSESSKQLLYPETEPAQEPAQEPAQEQQRFRGLVPILGILAIVLICGGLGLWVRSLQTSQPEPGQIPPPPESPSSTPSEIPSPSPELPSPELPAPPQSPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUX3</accession>
    <name>A0A2G4EUX3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3 8">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 8">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7 8">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">malQ</name>
        <name evidence="9" type="ORF">CP500_022015</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3 8"/>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53331">
        <property type="protein sequence ID" value="PHX53331"/>
        <property type="gene ID" value="CP500_022015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32438">
        <property type="entry name" value="PTHR32438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00217">
        <property type="entry name" value="malQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="502" mass="58084" checksum="F58167B5D7202A4F" modified="2018-01-31" version="1">MLFPRSSGILLHPTSFPSRFGVGDMGIEAYRFIDFLVESDQQYWQILPLGPTGYGNSPYSCYSAMAGNPMLISPEILRDEQLVTDEDLANWPEFSLDTVEFERAVALKLPLLKKACENFQAKASPVQQREFSAFCESKASWLEDYALFMALKDNFGGVSWNNWEAEIAHRKPESLEKWRQQLNTEIYYYKYVQFEFFRQWTELKRYANLRDIKIIGDIPIYVAHDSADVWSHPETFCLDEPTGEPALMAGVPPDYFSETGQLWGNPVYNWEQLQANNFQWWVERFEAIFDYVDVTRIDHFRGFEAYWAVKRGQKNAIEGEWIQAPGIALFEVINEKFGNLPIIAEDLGVITPEVEDLRDRFEFPGMKILQFAFNGGPGNPFLPFNFERNCVVYTGTHDNDTTVGWFNQLQDYERDEVYRYLGCIDPAGIHWSLIRMAWGSIANMAVVPFQDLLGLGTDARMNFPGKADGNWGWRYRSEALNWEVRDRLKTMTHICGRSPNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV53</accession>
    <name>A0A2G4EV53_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53411">
        <property type="protein sequence ID" value="PHX53411"/>
        <property type="gene ID" value="CP500_021630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="189" mass="21810" checksum="A451B91EA8EE833B" modified="2018-01-31" version="1">MIAIPSGFSPEEYLSLEHENTIRHEYQRGLVYAMAGGSDDNDELSLNLIELLRQKLRDGGCSVRSGNVKVNYAGEFFYYPDAFVTCDPRDRSDRYVKRYPKFIAEVLSPSTKKFDRTDKFEDYQQLESLEEYVLISQDEMRVECRRRVKDGSGERWETVVYGAGDLVMLQSIELEVAIAELYRGVSFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVC0</accession>
    <name>A0A2G4EVC0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FHA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000190">
        <property type="protein sequence ID" value="PHX53492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53492">
        <property type="protein sequence ID" value="PHX53492"/>
        <property type="gene ID" value="CP500_021230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="26"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="151" mass="16876" checksum="32D0A04418809777" modified="2018-01-31" version="1">MITLTLLHPIQSVPVQSWCFESEPVVRIGRSNDNDVIIYSAVVSRHHVELWNNPFGWEIINFGANGTYIDDQPISQILVVDGMTIRLGNSGPSIRIRVEGTNLQSEKVRRPPPPSPSKKDKSSAENQTLSPFREEIDDEDGASTQIDFGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVC1</accession>
    <name>A0A2G4EVC1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000191">
        <property type="protein sequence ID" value="PHX53483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53483">
        <property type="protein sequence ID" value="PHX53483"/>
        <property type="gene ID" value="CP500_021255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013666783" evidence="1">
        <location>
            <begin position="25"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="165" mass="17869" checksum="B5C73C932CBA1663" modified="2018-01-31" version="1">MKLRQLAAFLLTLSILIFPLPAWAQSKYYPPPLSFSNAELTRRNFSGQVLRVAEFSNANMDLTNFSNADLRGAIMSASVMTQANLHGANLTNAMIDQIKFTNADLSDAILVETILLRSTFDGVDITGADFTDAIMDGAQIKELCKIASGSNSQTGVSTRDSLGCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVG6</accession>
    <name>A0A2G4EVG6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000198">
        <property type="protein sequence ID" value="PHX53430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53430">
        <property type="protein sequence ID" value="PHX53430"/>
        <property type="gene ID" value="CP500_021540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06533">
        <property type="entry name" value="Glyco_transf_WecG_TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004629">
        <property type="entry name" value="WecG_TagA_CpsF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34136">
        <property type="entry name" value="PTHR34136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03808">
        <property type="entry name" value="Glyco_tran_WecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00696">
        <property type="entry name" value="wecG_tagA_cpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="30225" checksum="6AA9A192E99A7F41" modified="2018-01-31" version="1">MIDLGKKNVLGILVNAVNYEAAVSKIIDAAHTRTPMSVSALAVHGVMTGVLDSTHRYRLNHIDLVLPDGQPVRWALNWLYNTGLPDRVCGPVAMLQICERAAEEGLSIYLYGSTNLVLDALSKNLCQRFPKLIIAGMQPSKFKTISFEEKQKIAQEIRNSGAAITFVGLGCPRQEVWVYEYRDNLSMPLIAVGAAYDFHSGNVTKSPDFLGKLGLEWLFRLIMEPRRLWQRYVLLNPLYIWLFLLQALKLKQFDPKDATPPMEEMLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVK0</accession>
    <name>A0A2G4EVK0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53572">
        <property type="protein sequence ID" value="PHX53572"/>
        <property type="gene ID" value="CP500_020740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="22"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="193" mass="21633" checksum="F574889AC35AB861" modified="2018-01-31" version="1">MVVAISKAGLGTGAAFLSNVTWETLEKLDVDLAETGARLTYLDGCLEIMTPLSEAHEEPRNTLGQVLEMYMRTKDIRFYGRGSTTIGMKELGARKEPDESYCLGTRKSVPDLAIEVTVTSGGIDTLEIYRRVGVQEVWFWEDGVISVYCLRSTGYELVSKSELLPELDLRSIEFYSRMADQYDAVNAFMRSMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVP1</accession>
    <name>A0A2G4EVP1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-glycero-beta-D-manno-heptose-7-phosphate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_020620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000174">
        <property type="protein sequence ID" value="PHX53599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53599">
        <property type="protein sequence ID" value="PHX53599"/>
        <property type="gene ID" value="CP500_020620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01172">
        <property type="entry name" value="RfaE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011913">
        <property type="entry name" value="RfaE_dom_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="44"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="363" mass="39240" checksum="18632621D54CE72D" modified="2018-01-31" version="1">MTNDYSDFLPQLRASTERLLFLLDCFDRAQVLAIGDLTLDEFVTGQVERISREAPVLILRYENTRQVPGGGANAVYNLAKMGGKVKVAGLVGKDDQGKALCGIFEAAGIDTAGIFVDSQRPTVTKTRISGHARQSVTQQIVRVDRKSDELPDLDLQLQLADYIRQQIPMVDAVVCSDYGDGVLTNLAIESAVVRGKTIVDAQTNLQRYSGAMLFTPNLPEAEQAVGYSIDNSQALMQAGRDLLNLTQAQKILITRGDEGMSLFEIVQVEAIKNSPPTTSLCEDGELAIQRWDIPPFNKTDVFDVTGAGDTVVAAMTLALCVGASGWEAAVLGNLAASIVVRQFGTATTNVEEMKEALKAMSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVQ0</accession>
    <name>A0A2G4EVQ0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein PatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_021005</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Controls heterocyst pattern formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell septum</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="1">By nitrogen starvation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000182">
        <property type="protein sequence ID" value="PHX53536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53536">
        <property type="protein sequence ID" value="PHX53536"/>
        <property type="gene ID" value="CP500_021005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043158">
        <property type="term" value="P:heterocyst differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024186">
        <property type="entry name" value="Sig_transdc_resp-reg_PatA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005897">
        <property type="entry name" value="RR_PatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="1" id="KW-0364">Heterocyst</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="260"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR005897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="403" mass="45898" checksum="1AD44E27971C5812" modified="2018-01-31" version="1">MSTTAIGYKTLSHTLAMLSQKQASGKLLLEQGEQQWQLYFFRGCLIYATGGCHRARRWYRAIGQHCRNFQVDLRELDAGELWEYQLLQQGIAENEMNLEQARAIVRSSVSEVFFSLISQSSLRREWHPSKKYVSNIIPSLLLSLTEVQQLWYSTQQIWQKWKAMSLWPIEPEQAPLLRVPEELKNRFSSNSLLSLTKVLNGENTLWDIAFKRKQCVTVATRALHNYIKQGLVNFRTVPDLPSPIEQWRLAAAIAKPGRPLIACIDDSPTVCAFLEQILCEGGYRVLKIQDPMQGVGLLAKHNPALIFMDVVMPKTNGFALCNFLRKTSTFQETPIVFLTSKNSIIDRTRAKLIGASDFLSKPARPEKVLQVVDKYLKAKSDRSPLAVRHNDLLNSHRLTLANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVQ3</accession>
    <name>A0A2G4EVQ3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HEPN_RiboL-PSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000171">
        <property type="protein sequence ID" value="PHX53621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53621">
        <property type="protein sequence ID" value="PHX53621"/>
        <property type="gene ID" value="CP500_020515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041519">
        <property type="entry name" value="HEPN_RiboL-PSP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18735">
        <property type="entry name" value="HEPN_RiboL-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN_RiboL-PSP" evidence="1">
        <location>
            <begin position="14"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="22758" checksum="BEF9CB5EDB20425D" modified="2018-01-31" version="1">MQSAIDLFRISITRVRDLIAVHNSLKAQASSVLDFSDMLRAALVLAVSALDYYIHEVVRIGMLEIHRGQRLEPPAFSGFQISLGNARAGINAGQNIDSWLEDEIRQRHSYKSFQQPNAIADAVRLICDKKLWEEVSMNMGSPAKDIKQQLSRIVDRRNKIAHEADIDPSYPIGDRWPIDELLVNEAVDFLEQVVESIHKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVU2</accession>
    <name>A0A2G4EVU2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gfo/Idh/MocA family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000220">
        <property type="protein sequence ID" value="PHX53297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53297">
        <property type="protein sequence ID" value="PHX53297"/>
        <property type="gene ID" value="CP500_022230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="18"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="167"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="350" mass="38429" checksum="53045D556AD6D864" modified="2018-01-31" version="1">MSLGYANVFGHRGQPEPLRIGVIGVGNMGQHHTRVLSLLKDIELVGIADINVERGIDVASKYRVRFFEDYRDLLAHVDAVCVAVPTRLHHPVGMSCLQAGVHVLIEKPIAASITEAESLVNAAAESHRILQVGHIERFNPAFQELGKVLKTEELLALEAHRMSPYSDRANDVSVVLDLMIHDIDLLLELASSPVVKLTASGSRASNSGYLDYVTATLNFANGIVATLTASKVTHRKLRSIVAHCKNSLTEADFLNNEILIHRQTTANYVTDYGQVLYRQDGLIEKVYTSNIEPLHAELEHFINCVRGGNKPSVGGEQALKALRLASSIEQMALDGQAWYPKELESTLQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWD7</accession>
    <name>A0A2G4EWD7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAA hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000148">
        <property type="protein sequence ID" value="PHX53855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53855">
        <property type="protein sequence ID" value="PHX53855"/>
        <property type="gene ID" value="CP500_019240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018833">
        <property type="entry name" value="DUF2437"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10370">
        <property type="entry name" value="DUF2437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2437" evidence="2">
        <location>
            <begin position="4"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="59"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="258" mass="28366" checksum="6D9FEF6E624EEC7D" modified="2018-01-31" version="1">MASRYVRVKTAQGQIHYGLLQLSRSVQVLDAPPWLKGQPTDLELPPDSYQILAPCSPSKIIAVGKNYSDHAAEMGGSVPEEPLLFFKPPTAVIPTGGAIRYPQQSERVDYEGELALVIGEHCTQCSPEEAQGKIWGYTIANDVTARDLQKRDNQWARAKGFDTFCPLGPWIVRELSPAAQLQTFVNDSDRPVQSDRIDRMVFSPDFIVSYISQIMTLIPGDVILTGTPEGVGPLQIGDRVRIEIEGIGSLENTVVIGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWE9</accession>
    <name>A0A2G4EWE9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000149">
        <property type="protein sequence ID" value="PHX53849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53849">
        <property type="protein sequence ID" value="PHX53849"/>
        <property type="gene ID" value="CP500_019325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="189"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="479" mass="53734" checksum="07CD47D3B3878776" modified="2018-01-31" version="1">MLNTSCIEIPVPIVSEASRSEFRLDSTLQELSLYDFHVEATDVGSKIAQMLEAYPLLPGVILTDMGQFAGMISRRRFLEFISRPFGRELFLKRPVRALYRFAQTEILIFPSDTLIVDAAKKSLVRSRELLYEPIVVQLSTETYCLLDAHELLVAQSTIHELATKLLRQQTQSQLIQTEKLASLGQMVAGVAHEIRNPVTCITGNLNFLSNYSKDLMELLSAYEKIVGENAEIDRLKERIEFDFLQEDWAEILKSMKVSAERLTELVTSLHTFSHMDETHRKEANIHECIDSTLLIMKNRLKYNIKVTKSYGDLPLVKCYSGQLSQVFMNIISNAADALEEIKGKTGFVAAITIETEVIDVADGDCVSSELMQNYVRGDLENSKQLSLVNQKAQLNSEVAEKSQSHGWIAIRIADNGPGIPPEIQRRIFETFFTTKPAGKGTGLGLAITHQIVTEKHKGKLNLHSTPGTGTEFEILLPMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWI3</accession>
    <name>A0A2G4EWI3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_019060</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000143">
        <property type="protein sequence ID" value="PHX53894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53894">
        <property type="protein sequence ID" value="PHX53894"/>
        <property type="gene ID" value="CP500_019060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="7"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="PHYTOCHROME_2" evidence="6">
        <location>
            <begin position="158"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="344"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="419"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="540"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="622"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="861"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="979" mass="110484" checksum="479A3B517BB15C18" modified="2018-01-31" version="1">MGQLSRTILIVDDSPEDRELYRRYMLRDRDYSYTILEAGLGRIGLELWQQHQPDAILLDYRLPDLDGLEFLVKLQSFTQQPYLPVIVVTGQGNEAIAVQAMKSGAQDYLVKEHITTAGLHLAVNGAIATVQLHTQLQQSHERERLISQITRKIHQTLDLQEIMETTVTEVQQFLHTDRVLFFQIQPDGNGTVVAESVGSEWRSLLSSTMYDPCLAENYFRFSPSQSISHDPTFAEDYVERYRQGQVTAIADIQDGSIDPCHVEFLAQFQVKANLVVPILHENQFWGLLIAHHCAAPRAWQPLEIDLLKELATQVSIALRQAELYQQAQHELIERKRIAEVLQESEERFRQLTENIDAVFWIKEMPEDRVCYVSPAYERLWKLNPQELYDDRQVWINYIHPDDREWTARAFQEKAATGQFDEEYRLILADSSIRWVHDRCFPLRDGAGEIYRFAGIAQDITDRKQAEEALRQSEEFKNRMLESSPDCIKVLNLDGQLLYMNTGGLCLLEIDDIAPYLNAEWLCFWDGDYRQQAEQAFAAAASGEVYLFRGYCPTAKGTPKWWEVIVSPILDASGLVERVLVISRDITDRQQAEIERDRLFEQEQVARAEAERANRIKDEFLTVLSHELRSPLSPILGWAKLLQTRNFDPAKTAQALATIERNAKLQVKLIDDLLDIAKVLRGKLSIDTAPVNLIFIIESAIDTVRAAAVAKSILIHPVLPKIGLVSGDATRLQQVVWNLLSNAIKFTPNHGQVDIRLEQIDNQARITISDTGKGINPDFLPYIFESFRQEDASTTRKYGGLGLGLTIVRQLVEAHGGTIVADSPGKELGATFTVQLPLLNIEPENNQTGDLPPQIFDLTGIRVLAVDDELDTRELLTALLTQYGAEVLTVASVAEVLTSLKSFQPDVLVSDIGMPEVDGYTLIQQIRALPPEQGGQLPAIALTAYATKGDRQRAIASGYQQHLIKPLEPELLAEAIVALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWK1</accession>
    <name>A0A2G4EWK1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_018980</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53901">
        <property type="protein sequence ID" value="PHX53901"/>
        <property type="gene ID" value="CP500_018980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="4">
        <location>
            <begin position="176"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="135"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="246" mass="27841" checksum="4853589900895D6E" modified="2018-01-31" version="1">MPLTILVADDDFATRLSINDYLEILGYSVIAAENGKEALGLVEEFQPHLIVTDITMPEMDGYELVRRVRTRPAFRLLPVIFLTERTSTEERIRGYQMGCDNFLAKPFELSELGVVIRSLLDRYALIAQAPSRSPEPEIIHTEGRNRVKGNGELDFSTQKSEMRDSLRDSSASRASMGPSSPMLTQREREVLNLLTEGLSNILIGDRLHLSPRTVEKHVSSLFRKTDSSNRAELVRFAMEHHLVGNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWK3</accession>
    <name>A0A2G4EWK3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Septum site-determining protein MinD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cell division inhibitor MinD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">minD</name>
        <name evidence="8" type="ORF">CP500_018925</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParA family. MinD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000141">
        <property type="protein sequence ID" value="PHX53913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53913">
        <property type="protein sequence ID" value="PHX53913"/>
        <property type="gene ID" value="CP500_018925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010223">
        <property type="entry name" value="MinD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025501">
        <property type="entry name" value="MinD_FleN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003092">
        <property type="entry name" value="MinD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01968">
        <property type="entry name" value="minD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="7">
        <location>
            <begin position="5"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="29342" checksum="681CB30556085C4A" modified="2018-01-31" version="1">MARIIVVTSGKGGVGKTTSTANLGMALAKRGRSVAVIDADFGLRNLDLLLGLENRIVYTALEVLAGECRLEQALVKDKRQPRLVLLPAAQTRMKDAISAEQMKQLVGMLGEKYDYILIDSPAGIEQGFQNAIAPAQEGIIVTTPEIAAVRDADRVIGLLEANNVKKIRLIVNRIRPAMVLANDMMSVQDVREILAIPLLGVVPDDERVIVSTNRGEPLVLSETPSLAGTAFDNIARRLEGEKVDFLDLNPRPETFFSRLRKFFNTKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWL2</accession>
    <name>A0A2G4EWL2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53924">
        <property type="protein sequence ID" value="PHX53924"/>
        <property type="gene ID" value="CP500_018880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="12992" checksum="9F559DA645BF4F53" modified="2018-01-31" version="1">MDSLEEYREIICSIITEYAQIPYAYGDIQRHTIFDTNNDRYLLMILGWEEVRQVHGCLIHVEIIDSKIWIHRDGTEDGIANEFLNAGIPKDRIVLGFRSPEMRKYTEFAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWV2</accession>
    <name>A0A2G4EWV2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54025">
        <property type="protein sequence ID" value="PHX54025"/>
        <property type="gene ID" value="CP500_018300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="12215" checksum="627B86892BA9886B" modified="2018-01-31" version="1">MGLKIIESYDGSFVIEPEAKAVLLSLLTAESFLQQIASQLKCSRLEFTDLLFQPVPYSSETPKGMPAEFEKYHGKSDFAIVNVPPNFMFQAKVFKPSRLCAIYRVFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWX7</accession>
    <name>A0A2G4EWX7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53978">
        <property type="protein sequence ID" value="PHX53978"/>
        <property type="gene ID" value="CP500_018555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="506"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="598" mass="66567" checksum="C9CF2BB6157DA0DB" modified="2018-01-31" version="1">MARPENPCLSIAIARMKTSGANHFATWVLQAPYPSGYVHHDCMWPDTLSQSWQAWQEMFSSSGTIHELPLNPDRTFGSPQNSQKILAETAKLSPHSLEIPRSQVPINLSPEGLREGEKTPPPQPASYSSRLMQHFGINLWQWLFEGPIQGSLQESKGIAIGQNQPLRVRLDLREPYLIALPWEIMQPQPGQPAISLSQQLLFSRTTSNVEPLGPLRLAESLNILLVLGQKDPGSAVNSQFSTSNNRQLQLEKEALDLRQVLETASKTDDSGKYLDVSVATHVDTLIEPSRAQLISRLETQAYNILFYAGHGMPGPDGGFLFLGPDTIINGTELAQVLVRGGVTLAVFNACWGAQPAVEMVDLSNGQKQAIARSSLAEVLIHHGVPAVLGMRDSIADREALSFIQTFAQALAGRMSIDRAVAIARQQLLTLYKFNQPAWTLPVLYMHPEFDGELTDPVDDIKTELPVNSSTWLGRLPSAAYLRGRGENEKSQSSNPDRVWPIRAGMVRVGRWEENDVVIREQWVSQKHAEIFCRNSVVDGREEPSYFLRDFSRYGTLVLGDDGWQRVHHQELLLRSGVQLKFGSSQGQMFEFTIEVPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX74</accession>
    <name>A0A2G4EX74_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cyanobacterial UDP-glucose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">UDP-glucose pyrophosphorylase</fullName>
            <shortName evidence="1">UDP-Glc PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cugP</name>
        <name evidence="3" type="ORF">CP500_018115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CugP-type UDP-glucose pyrophosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54078">
        <property type="protein sequence ID" value="PHX54078"/>
        <property type="gene ID" value="CP500_018115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002134">
        <property type="term" value="F:UTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02085">
        <property type="entry name" value="CugP_cyano"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037538">
        <property type="entry name" value="CugP_cyano"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="387" mass="42497" checksum="942331FDA463751B" modified="2018-01-31" version="1">MKAMILAAGKGTRVRPITQTIPKPMIPILQKPVMEFLVELLRQHGFDEIMVNVSHLADVIENYFRDGQKFGVQIGYSFEGRIEDGKMIGEAVGSAGGMKRIQEFSPFFDDTFVVLCGDALIDLDLTAAVKWHREKGAIATIVMKSVPREAVSSYGVVVTDDSGKIQAFQEKPSVEAALSTDINTGIYIFEPEIFNYIPSDTEYDIGSDLFPKLVEAGAPFYGISMDFEWVDIGKVPDYWRAIQSVLLGEVKNVSIPGIEVRPGIHAGLNVAVNWDKVDITGPVYIGGMTIIEDGAKIVGPTMIGPNCWLCSGATVENSVIFEYSRLGPEVRLVDKLVFGRYCVDKTGATIDLQAAALDWLITDARQVLPTQQVEERRAIADLLNTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX75</accession>
    <name>A0A2G4EX75_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NYN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006633075.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000120.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54145">
        <property type="protein sequence ID" value="PHX54145"/>
        <property type="gene ID" value="CP500_017620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="7"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="20365" checksum="4A649D9E2B809A9F" modified="2018-01-31" version="1">MTNLMNRLSIFVDGNNMFYAQQKNGWFFDPRRVLEYFKTSQPNVILINAFWYTGLKDPQDQRGFRDALISLGYTVRTKILKEYYDDASGRYSQKANLDIEIVVDMFNTVDQYDQVVLFSGDGDFERAIELLRSKNTHITVVSTEGMIARELRNATDRYIDLNEIREHIEKMDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXA4</accession>
    <name>A0A2G4EXA4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54159">
        <property type="protein sequence ID" value="PHX54159"/>
        <property type="gene ID" value="CP500_017695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="293" mass="34021" checksum="A78F1803FE4E8662" modified="2018-01-31" version="1">MRFINPKTDFAFKKIFSSNESKPILISFLNAMIYDGNPTIADLEIIDPYLASRVQYLKDSYLDVKARLTGGATVIIEMQVLNVESFAKRVVYNTAKTYSTQLIRGEGYFKLKPVIALTITDFEMFDNDREVISHFVFKEKKRLFDYIDPEIEMIFIELPKFNKQLDQLETLTDKWVYFMKNAPCLEVVPETMETVSEIQQAFAIANETNLNPEELADLEARERYILDQQGILRKGREEGREEGREEGREEGREEGMREKALEIARQLLNVLDDRTISQTTGLSVEDIQKLREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXG4</accession>
    <name>A0A2G4EXG4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54211">
        <property type="protein sequence ID" value="PHX54211"/>
        <property type="gene ID" value="CP500_017235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="12496" checksum="ECB73E4AAB010215" modified="2018-01-31" version="1">MDTSATYREIVKQVILQYAKLRPSHGDIRLDPVLDETRDRYALMQVGWDRGRRVRGNLIYITLEDEKVYIEYDGMECGITQNLIEQGISENDIVLAFLPYSLTALTAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXJ6</accession>
    <name>A0A2G4EXJ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54241">
        <property type="protein sequence ID" value="PHX54241"/>
        <property type="gene ID" value="CP500_017200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="8"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="493"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="713" mass="81881" checksum="D78D7239C644404F" modified="2018-01-31" version="1">MTIPPICSIIVVNYNGFRQTKDCLKSLQKLAYPEEQLDLILIDNCSQDDSVKSLGELFPKVRIFVNSVNNFAKALNLGISQSTGQYIAFLNNDATLDSCWLEILVKRLETNPKAGAASGKLLFKDGRINSVGIQQLPNFYWRDVGFGEKDSGQYDTERTVEGLCWATVLFRRECLADVGPIDEDFVMYFEDVEFSKRCQKRGWKMLYIPTAIAHHEYRGSSRGSKLTEYFCNRNRFLYLAKHEPLQLVSAIHTSDFFTNKQYDLLFESIFVAIKKLLEYQKPEIVETVLSQLSEKLAVIYSRLKVDRILSRLQVIRGDRKMSIAIYDHGLHFIGGGQKYVATMASLLQNQFDITFIANKPVAISDLESWYGLNLSECKIKVIPLQFYEKFGMQCIDSSMITDELENPFDKIAKESKHYDIFVNANQLEKVKPLSPISVFFCHFPNTFRNRHFAVDDYTFIIANSQFTVKWLDKRWNLKPTFLLYPPVEMATAEVPKEKIILAVGQFEAGGTKKQIELIKAFRTLLVDYPEQMTGWRLILVGSSVPRNPYLKTVQNLLKQDMRAIELKVNADLDEVKSLYAKASIFWHGCGLGEVNPQRFEHFGMATVEAMRNRCVPIVFNGGGQPEIVENGRSGFLFNTVEELCQHSHQLMVNPDLLAEFQGVAEQRSQYFRISRFEEKVKEFFEIIRQEYATIRLPNPADVAQMVDTNRDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXL2</accession>
    <name>A0A2G4EXL2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_31 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54273">
        <property type="protein sequence ID" value="PHX54273"/>
        <property type="gene ID" value="CP500_017025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="148"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="454" mass="51401" checksum="A5A927BD6C134CCD" modified="2018-01-31" version="1">MTISFGETFDKVRECFQEQSIVDTLVPKLKSVTIIRDVNGKIRIFLEPLETITIQESETTDLNTFFSRKLGSYYGNDIWLPAGEKDAYKALIKTIEDERVFAFWDDESCLPRWYILERHIAKQAWTDQQIGTPPWPQYVVDQKHKPAIVSFFSFKGGVGRTSALVATALTLARNGHRVAIVDLDLEAPGLATIFSPDSSNNLGVIDYLLEKKIQNQDWKLRTHIIPINEQTLLGDYGQPLQLLPAGTVDDNYLEKLARLDFQNLVDGELQSTMQNMLRELESAVRPLDFILMDARAGFHDIGGLAITNLSHGVVIFGTQSRQSWAGLTHVIRHLASSGVDERLPLILVHSMAPANGIPGRETELTEFQEQAYIVFKENYYSEDETVPDPNNREEPFFPVVVPYQESLRGDIALFSRNSQSNRLSGLVEIMTNSPYQEIAEKLCDLFGREFQKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXM7</accession>
    <name>A0A2G4EXM7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54228">
        <property type="protein sequence ID" value="PHX54228"/>
        <property type="gene ID" value="CP500_017330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031975">
        <property type="entry name" value="Pilin_GH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16734">
        <property type="entry name" value="Pilin_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="25151" checksum="2A1F1D1A07AF8990" modified="2018-01-31" version="1">MELDQKPETNLQHLTTTPETDGIFDQEKSSPLKSEVVQSPPEAVAIAPQKKGRRWYLVKGGILFLILNLGIEGSNYFSPKSSCCVRPEPEQYVHSINRGLQATFAENGTFTNSVNELGLGIKTQTKHFKYSVSTTKTAAFSYGIPYKDAFKTVYFGLFNWDERIELKSYVGAVFVVPTTNGNPNSDQNEMTTISIVCRAVAPSKTQPANPLLKDGQPMCGIGTENAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXP0</accession>
    <name>A0A2G4EXP0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2281 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54303">
        <property type="protein sequence ID" value="PHX54303"/>
        <property type="gene ID" value="CP500_016850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018739">
        <property type="entry name" value="DUF2281"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10047">
        <property type="entry name" value="DUF2281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2281" evidence="1">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8825" checksum="9DA8631D5718FF45" modified="2018-01-31" version="1">MNLEQAVVDKLRTLPPERQQEVLDFAEFLQQKTIFKRPLKSVKGMCADLKVDITEEDIAQVRQEMWKYFPREDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXQ4</accession>
    <name>A0A2G4EXQ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metal ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54301">
        <property type="protein sequence ID" value="PHX54301"/>
        <property type="gene ID" value="CP500_016840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="245" mass="27519" checksum="B2D04F3553523555" modified="2018-01-31" version="1">MLEVQDLAVNYRGISALNNINFHLESGQLTGVFGPNGAGKSTMVKAMLGLIPACRGQVKYQGRLLKEQLGRVAYVPQRSQIDWDYPITVWNAVMMARTVHTGWFRSPSRQSQELVKGALLRVEMWDLRDRQIGELSGGQQQRIFLARAIAQQADLLFFDEPFNAIDKTTEEIIFDIFAELKAENKTLLVISHDLGQTLKEYDNLLLLNKQLIAIGSCREVLTAANIQKAYGYQGKSISIMLNKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXS6</accession>
    <name>A0A2G4EXS6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AbrB family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54329">
        <property type="protein sequence ID" value="PHX54329"/>
        <property type="gene ID" value="CP500_016780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027360">
        <property type="entry name" value="AbrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42182">
        <property type="entry name" value="PTHR42182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14250">
        <property type="entry name" value="AbrB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="75"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="14862" checksum="140292A9B1B8D071" modified="2018-01-31" version="1">MAETATAPLTGKGLLQKIKGSDLPRRELAKLCGYFTVSKSGETRINLAEFYDAVLAAKGIELEKSKADGRGREASYRASVHKNGSIVIGANYTQEMGLKPGDEFEIKLGYKHIRLIQIDMDRPDVVADDEEDTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYD7</accession>
    <name>A0A2G4EYD7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54543">
        <property type="protein sequence ID" value="PHX54543"/>
        <property type="gene ID" value="CP500_015595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="17"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10635" checksum="48D5FD721A648B34" modified="2018-01-31" version="1">MVNEQSWEEIKESLKVGTKLKGVVTKHWPFGIFVALPGIKFTGIVELGNFKDEGFMTRDEYPAVGSSVDVVVLAFKETGQQIWLGMKPSQFNQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYK8</accession>
    <name>A0A2G4EYK8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_015290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54601">
        <property type="protein sequence ID" value="PHX54601"/>
        <property type="gene ID" value="CP500_015290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="3">
        <location>
            <begin position="8"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="145" mass="16020" checksum="92AB60B9F3164894" modified="2018-01-31" version="1">MSDQKLWISALGLDIGLKRVGIAGCDGTGLIATGITTLVRSSFDRDLAYLRELVRERNVQMLVSGLPYSLNGDVGAQARQVQKYATRIATALELPLEYVDERLTSVHAEELIQAQGISPSQNKGLIDRKAAALILQRWLDERRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYR0</accession>
    <name>A0A2G4EYR0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54661">
        <property type="protein sequence ID" value="PHX54661"/>
        <property type="gene ID" value="CP500_014855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="22657" checksum="7413A50F6FC49A11" modified="2018-01-31" version="1">MAYSNFSLSDLIKQFGFILKDKNDLFAHILEVGYSEYLDFTLDYNIRIASEINTEKARSEMIITPILLELRRMLDDKISLFSGKEFNVDFEKGLNGACDFLISLSESQIVIMAPVIAIVEAKKEDLIGGLGQCAAEMYAAQLFNQREGNQIPIIYGVMTSGTVWRFLKLEGNALDVDVAEYYIKDVGKILGILSSLVKGTACQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYV5</accession>
    <name>A0A2G4EYV5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="4 5">4.2.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rfbB</name>
        <name evidence="7" type="ORF">CP500_014730</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:17221"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="EC" id="4.2.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="4 5"/>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54676">
        <property type="protein sequence ID" value="PHX54676"/>
        <property type="gene ID" value="CP500_014730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="6">
        <location>
            <begin position="17"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="368" mass="41481" checksum="7E6654E74771F5BF" modified="2018-01-31" version="1">MTDSKDQAIVRSPRRLLVTGGAGFIGSNFVHHWCSSYRGDRVVVLDALTYAGNRQTLASLEGGENFRFVQGDICDRSLIDTLLQTENIDTVAHFAAESHVDRSIIGPAAFVQTNVVGTFTLLEAFRKHFEAIEDKSLKAQMRFLHVSTDEVYGSLGPDDPAFTETTAYEPNSPYSASKAGSDHLARAYFHTYGVPTIITNCSNNYGPYHFPEKLIPLMCINMLLGKPLPVYGDGQNVRDWLYVLDHCRALDATINNGKPGETYNVGGNNEVKNLDLVKMLCQLMDELATDLPVRPCEKLITFVKDRAGHDRRYAIDATKIKTDLNWTPSVTVEEGMRRTVEWYLANRDWWEPLLSEEYQSYYRKVYAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYW2</accession>
    <name>A0A2G4EYW2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tfp pilus assembly protein PilF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54377">
        <property type="protein sequence ID" value="PHX54377"/>
        <property type="gene ID" value="CP500_016445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037919">
        <property type="entry name" value="OGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366">
        <property type="entry name" value="PTHR44366"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013821250" evidence="2">
        <location>
            <begin position="23"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="146"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="180"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="214"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="248"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="282"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="316"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="366" mass="40084" checksum="E14AF7ED72992D0C" modified="2018-01-31" version="1">MAVYKQSLLVFSTLLLAGIAVTAPLRALSAETTVQVNPENNANLDSLLRKGRELVDLGEYGKAIAIYEQAARLDAENPRIFSGIGYLEARQGNYQAAIEFYQQAISLQPNNADFQYALGYAMANLQNYPAAATAYRRAAQLDRKNVNALIGLGVVLFQQQDYSGAFKAYQQVIAIDPKNWQAYSSMGLVLIQQGNFSSAVNLLQQAAKLAPKQASVQLKLGTALLRSGNTSEGVLAFEEAAKLEPKNADMQLEIGELLRTQNDLDGALVAYQRAVGVRPNLVQAHAAIGEIQLEKQDSLGAIITFRRVIQLDPNRAEAYYNLGIALKRRDRTSEAVEAFKQALDTYRQQGNNDGAQKAETALRELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ02</accession>
    <name>A0A2G4EZ02_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54698">
        <property type="protein sequence ID" value="PHX54698"/>
        <property type="gene ID" value="CP500_014660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="21420" checksum="4099E73C2D7466AB" modified="2018-01-31" version="1">MSVQTQKWLFTVQEYHLMTEAGVFANNERVELIEGEIIQMAAIGTRHATCVRRLIRQFRQIPEESAILDVQNPIRLTERTEPQPDLVLLQFRLDYYETAHPMPSEVLLLVEVSDSTVDFDRDVKVPNYARSGIQEVWLCDLEVNCLEVYRNPTANGYTSIQKFERGEMVSPLAFPEFEVSVDLILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ09</accession>
    <name>A0A2G4EZ09_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type 2 lantipeptide synthetase LanM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54730">
        <property type="protein sequence ID" value="PHX54730"/>
        <property type="gene ID" value="CP500_014570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04792">
        <property type="entry name" value="LanM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017146">
        <property type="entry name" value="Lanti_2_LanM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037228">
        <property type="entry name" value="Lant_mod_RumM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="1">
        <location>
            <begin position="241"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1077" mass="120863" checksum="689662C7C84AE44E" modified="2018-01-31" version="1">MLDNLAVADLACRASNLSERLLIIKQLANSNVLAKCTKQLEKIDTWILSKLSGKLAAIQLKQQLFQQDISNIPSKDILEKTLTDYKLYGINIEKLSESDRLPFIQPHSTWLNLYQSALTTLDLPKANFADSCWYEPNIYYGRFAKVCEPFLRLIQQKLQPICTVINQEKADYSINQQVITNIQLELLNRLEISLARAIEADINVYCYQNKITKSSDSEAYITYLEQSFKDEQSYHRFYCKFPVLGRWLAQVTQFIVKFGEELIQRLTSDRAEISATFFSGKQISRIKYLKLGQSDPHAEGNSVVIVELELSNSEQVTIVYKPRGIQSEAAMQGLLETLSKAKVIEFATYKVLCKDGYGYAEFIPSGKNQVTSEKEIKRFYHQLGGYLAIFHILGGGDMHYENILVANSNAFICDCETILEVLPQGMEKLPDTLLDSVFKTGMLDWPRAKQTDNSSLISLTGYNGGESYQTPFAAPQINHRMSLALAVEHQVGVHVEVAGTNRIYYNGKLVQPHDYQQSIVDGFNKVYSWVQQNATQTIKLIEELFASSSVRFVNRATQVYAKLLDAARHPKCLADPLEVDLIFHSLIEYPRVWDETGKLAALEMAALWQLDVPIFTAPANSYDLSYNYQQQLSDALAISPSHNARDRIKRLSTDNQIRQNQYIYASLSTGEINNKHFVASAVNYAEQIGRQLCELLQPSSSAPWKTIDFTPTGKRLVDINASLYNGSAGICLFLAYLDTIQPQAQFRSAAERALTHAIEQRDTTMLGAFQGTAGLIYLLTHLAHLWDKPALLDQAVELCAEITPQISQDRYYDILHGVAGVIPVMLGLVQATSGKGLSCAQQCAQYLLQQAICQDDTLSWSCDSELARANLTGFSHGASGIGWALILLGCHTNQSEYIIAGRQAFAYEATQFDPAVRNWYDLRKSVMTRETIKPQFANFWCNGAAGIGFSRLASWVALGKSDADMLREAYTALDVSVRNFHRLENDSLCHGKSGNAELLLRFAKLADEPYLQMEANVQAQAQWRNFERSRRWICGAGGNDIFPDLMLGLAGIGMHFLRLAYPERVPSPLLLDPPSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ22</accession>
    <name>A0A2G4EZ22_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GGACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54759">
        <property type="protein sequence ID" value="PHX54759"/>
        <property type="gene ID" value="CP500_014345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="SSF110857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGACT" evidence="1">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="14924" checksum="E479BE18D247BF6B" modified="2018-01-31" version="1">MSQTAIAVKRVFICGSALRGQPDNSNLGDAKFIREAKTRPIYRLHSAENGWHPAIYEVVTSGVSIPGEVYELTSDQFEQLAGGEPPHMYPSDVVLDDGEVLTAFFYPQELVEKYQWEDISDRGGWAAYKASAGPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ44</accession>
    <name>A0A2G4EZ44_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Asparagine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54792">
        <property type="protein sequence ID" value="PHX54792"/>
        <property type="gene ID" value="CP500_014080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="192"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="1">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="580" mass="64801" checksum="A4706917ACC34017" modified="2018-01-31" version="1">MGAIAKPAHFIGYWGHEDRTKTLSRLVPDYRIRSGKLSQWAIASASILKADTVTLNACGRFQPTDFPGDAWAGVETGQLRLGRDPFGRVPLYWMQLAETIWFSTQMQLLLRLIDSPEISAIALHSYACFSYVPTPLSAIEQIASVAAGTEIIWEIADINDLPKVRSLISAWQEAPQLLRREDEAIAQLQGLLQQAIDRQVADLPIDEPVGVLLSGGIDSSLVTALLVKAGLKVRAYALDFGVEAYSELPYAQQVADFFGIPLIRVAATGDAILGAIGPTAKALDAPYGDGTTAPLFLLKQAAAQDVRVVFNGENGDQLFAGWTNKPLIANGVYSAEHPAGKETFEQEYLRTFQRFYGYEKQMFSSEMLDRIQSHDLSIYLQDAIGVETCPSLLAKLRRASLMLKGAQNIQPRATALGFACGLWVRSPFCDPDLTDWTFQLPGELLLQGACEKYILKKASERWLPPEIVWREKRGMGVPLKVWYYREFWGAIGDRLNPNVLRSQNCWQPHLADSMLSGQLGVAMRDRYIGNNLWLLLMWQAWRTEVLGEIPVGRSLDHVFWLPPAIGQRIWKYRKRLTDDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZA6</accession>
    <name>A0A2G4EZA6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aspartyl protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54845">
        <property type="protein sequence ID" value="PHX54845"/>
        <property type="gene ID" value="CP500_014045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="15970" checksum="3275F70B15791C0E" modified="2018-01-31" version="1">METTTETPMGKVIATLVITNRLDEGKAEDGLIPIEQVRSVTLENVLVDTGATTLCLPKDVIARLGLKILKQVVVETATGISEARIFRDASIFLCGREGTFECLELPEGKTPLLGVIPMEALGIEVDLKHQRLKVLPDGPTETYLTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZD9</accession>
    <name>A0A2G4EZD9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54547">
        <property type="protein sequence ID" value="PHX54547"/>
        <property type="gene ID" value="CP500_015445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="578" mass="65332" checksum="1D56F80938BCF497" modified="2018-01-31" version="1">MFIASLQKFLTTTIHEKARSRTIFWLALSLTFAAIYGFLGLRQAFGGEYVVQDDARQHVFWMMRFVDRDLFPNDFIANYFQSAAPAGYSALYKIAATIGIHPLFFHKILPFFLSLISTYYCFSIALEMLPVPMTGFIASLLLNQHMWMTDDLASATPRAFIYPIFLAFLYYLLRRSLLPCLGAIGLMGLFYPPYALVAAGILVLRLVGWENGRLCLSRDRTNYLFCTTGLGVVFLVMLPYALDKSEFSPTYTAAEAKKMPEFAADGRNAFFRANPKHYWLTGRGSGMFPQSLFTPVTHCAALLWPLLLVWRSHFPLVKQIQSSIWVLLQLFLASSAMFLVAHATLFKLYQPGRYTAYSLRFIVVFLSAIGLTLIVDGVLNWAKENETKFGIKNLVAITTTAIIAFVVVCYPSLVANFPRVGYVEGKMPDLYQFFQQQPKDILIASIAGEADNLPTFSQRAVLVAKEYAVPYQKGYYSRYLQRINDLIRAQYTPDRAVLQKFINQYGIDFWMLDYNALTLQYLQDYGWIDVFDSTPEAMQVLKQGKTPVLAEAMTSCAVFQNGIVVVLETSCIAKLGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZR2</accession>
    <name>A0A2G4EZR2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55003">
        <property type="protein sequence ID" value="PHX55003"/>
        <property type="gene ID" value="CP500_013045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="10343" checksum="C4A922A285674D4C" modified="2018-01-31" version="1">MTQEFVPNDDKSVSASPGPNDESAAVSEQDVLCVTVTGSPKGVRETILTLYRLGFAEVGDWSPLQPAANPKQVMSVLIRRKLANGKSSRQSDGKPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZU8</accession>
    <name>A0A2G4EZU8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isoaspartyl peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55025">
        <property type="protein sequence ID" value="PHX55025"/>
        <property type="gene ID" value="CP500_012990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="PTHR10188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="215"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="236"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="3">
        <location>
            <begin position="186"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="324" mass="34031" checksum="34711492FEF7FD6F" modified="2018-01-31" version="1">MASQQIQPKLVIHGGAGSSLQGKGGLEAVRKSLYKVLEEVYPLLKDGASAVDAVVHGCRLLEDDPRFNAGTGSVVQSDGQIRMSASLMDGFVQRFSGAINVSRVQHPIELAKFLQTSDDRVLSDYGSAELLRELQLPIYDPMTDLRLHEWMEERKGNFSRAMAGVVAEPTSPPLSPLGKGGERGVGTIGVVALDAQGRLAAGTSTGGKGFERIGRVSDSAMPAGNYATGSAAVSCTGIGEDIIDECLAAKIVIRVTDGFSLKAALERSFAEADEHKRDFGAIGIDASGAIGCGKTSDVLLGAFHNGMQMGDCLEMSKGTLIFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZW8</accession>
    <name>A0A2G4EZW8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cell division protein FtsQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_012855</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55051">
        <property type="protein sequence ID" value="PHX55051"/>
        <property type="gene ID" value="CP500_012855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013685">
        <property type="entry name" value="POTRA_FtsQ_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08478">
        <property type="entry name" value="POTRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="9">
        <location>
            <begin position="56"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="300" mass="33404" checksum="98423579DDF30254" modified="2018-01-31" version="1">MASFASVSETELGRRRQELQRIRRARLAALVWQMLAATAMAGGLLWWIAQPTWLIARSEQVKVEGNHWLSDKAVRSLMPLSYPQSLWGIQPQALASKLEATGPIAKAKVTRNLFPPSLTVQVAERLPVAVAQPTAVVGRKTDKQKLGWLDAKGGWMPFDSYTTDKQSKNSSLGNNSQETQSQRSLPTLKVIGDLKLYRAEWPKFYQGFSDLSVKVFEIDWQNPNNLILKTEIGTVHLGPPSSRTIEQLKVLNRMRQLPKQLDSSKIAYIDLKNPASPTVHQVSIPSSSENSSPAPTRAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F003</accession>
    <name>A0A2G4F003_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF459 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55084">
        <property type="protein sequence ID" value="PHX55084"/>
        <property type="gene ID" value="CP500_012740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007407">
        <property type="entry name" value="DUF459"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04311">
        <property type="entry name" value="DUF459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="320" mass="36785" checksum="58F91E4B0A0921A1" modified="2018-01-31" version="1">MRDQEILLIATSVILTLIFTNLSLFLKSFSSTPFASPEIKQAARQIEMDVFRKSEQDFWSKIKDIDFDKTPSKSAKTEQKPAIKAKKATVKPAKKTIAAKPKLTRPYRKFLFVGDSVMLDLGTQLQYTLKEKYKITDTKLDYKVSSGLNRIDYYDWYARTRELINDYQPDVIIVLFGGNDTQDINDYQGKYRAIMTKEWQKAYQERVNKYAELLKYSSVQKVYWVGQSISNKSFYLNQFPIMNDIYKKASKISGRIQFISTWETFAEGGQFTPVVADKSGKRGYVKVNDGLHFTSHGAQIISDLIVDKMAADKVLKVPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F099</accession>
    <name>A0A2G4F099_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF86 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012085</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55192">
        <property type="protein sequence ID" value="PHX55192"/>
        <property type="gene ID" value="CP500_012085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008201">
        <property type="entry name" value="HepT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01934">
        <property type="entry name" value="DUF86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="13013" checksum="B770988F9A595F2B" modified="2018-01-31" version="1">MSRNNASLLDIYEAGQQILSYAQGLNRSELQGDKMRVSAILYQVLIMGEATKRLSPEFRSQHPQIPWSNIAGMRDTVAHEYDRIEFGILWAVIQNSIPELLEMITPLLPQESDPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0B1</accession>
    <name>A0A2G4F0B1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55186">
        <property type="protein sequence ID" value="PHX55186"/>
        <property type="gene ID" value="CP500_012045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="238"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="300" mass="34500" checksum="C3BAE40E0D3509CE" modified="2018-01-31" version="1">MKFINPQIDLAFKKIFGTTENKDILINFLNAIIYEAQPVIEDLDIIDPQTEIETVGVKDTYLDIKAKINGDKIALIELQLINVSSFGKRVLYNGATTYSLQLTGEERYERLKKVISLKIADFEMFANQPEVISRFVFKEKDHKSDSPDTELELVFVELPKFSKQLAELETTADQWIYFLKNSINLNTLPEILSAVPEIKKAFELTNEDNFTQQELKELARQEMWIQNQHSVVDVAREQATKKAQISLILRQMVKRLGKIEPETENHIRQLSIQNLESLGDAVLDFKNLSDLTAWLQTYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0B4</accession>
    <name>A0A2G4F0B4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RHH_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54887">
        <property type="protein sequence ID" value="PHX54887"/>
        <property type="gene ID" value="CP500_013710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012869">
        <property type="entry name" value="RHH_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07878">
        <property type="entry name" value="RHH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_5" evidence="1">
        <location>
            <begin position="44"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="11057" checksum="38D95FF42CB2DE68" modified="2018-01-31" version="1">MGVLFLTIYTVSHRVSLCKRRTKKVRSIYEVNSQLPNLPAKNLKRVTSYVPPNAYNVLEDWAKEEDRTVSNLVSRIVSQAVDAYLTKKTAKDEPTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0G5</accession>
    <name>A0A2G4F0G5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PAS domain-containing sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_011720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55243">
        <property type="protein sequence ID" value="PHX55243"/>
        <property type="gene ID" value="CP500_011720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="142"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="213"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="285"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="112"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="515" mass="58429" checksum="F8B0F39996702E3A" modified="2018-01-31" version="1">MINIFRKLLIPQETEYLLVNNHFIIQETSAAVQRFADTAGDALPGVDARICFPELIGIESILTSILLGQRSSFQVKGIARFTDNDHPLYFDLLAIEHENEQVDMPSKLLIVIEDATEKMVMKQSLIQRANEANLLIRALEASKDYINKVISSMGDALLVTTTLGIIKTVNQSAQLLFGYSEAEIIEQPLSMIVVEEKLLYQARHHYILSQKEFRIELEVVCTTKTGAEIWVEFSCAAIQTELKGLYDFVYIGRDITARKQQEIEIRRSLAKEQELREVKSRFFSMLAHEFGNPLNTILFSAQILKEYGDELTVEEKEEYLEHVKSASKHMAQLLDDVRLLSSAEARKLQFNPAPIDLQKFCSDLVESIKISFGKNNAICFTYRRVASRGRLLDNSYDDTQNLPAMDKKLLRHILTNLLSNGIKYSPIDSKVYFELHCDNEEAMFKIKDEGIGIPIEDQEQLFESYYRAQNVGKIPGTGLGLSIVKQCVDLHGGQIEFSSETGLGTTFIVTIPFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0K7</accession>
    <name>A0A2G4F0K7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tox-PL-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55286">
        <property type="protein sequence ID" value="PHX55286"/>
        <property type="gene ID" value="CP500_011610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028910">
        <property type="entry name" value="Tox-PL-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15643">
        <property type="entry name" value="Tox-PL-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tox-PL-2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="48" mass="5602" checksum="A0DFB4D19BA899B0" modified="2018-01-31" version="1">MLKIQINGEELIFDNIHNEGITKQEWLGKFYCLAIELGGQFEITEIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0T0</accession>
    <name>A0A2G4F0T0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SGNH/GDSL hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55348">
        <property type="protein sequence ID" value="PHX55348"/>
        <property type="gene ID" value="CP500_011150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="402" mass="46149" checksum="D29003E75FC12B5E" modified="2018-01-31" version="1">MRKLSLWGQQLSLILGGIMAGVFLGELALHLGGIKGLKKPSEPVSFDTYRFDDPAGAWSLNPGASFEWLGEGERSLIQANKDGLRDREHTKEKPPKTFRIAVVGDSFAEALQVPMEKTFWWKMRKQLNKKCTALGDRKVEVINFGVQGYGTAQELMTLRQKVWKYSPDLVILAFFPGNDLINNSKQLDFDKRRPFFLYKNGELVPDMSWLKMSPKEHEYLNFSHVDYLPTWLVNNSRILRLVRKVDLDNKKRLLDATEKERFPKNFQEPIEPVWKEAWLVTEGLITLMNQEVKAKKADFMVVIVSTGAQVHPDPIARQSYMKQFGIKDLYYPNHRIKSLGDRLNITTLDTVPRLREYAEKNKTCVQGFPNALACEGHWNSHGHEQVGQLIAENLCDKFKAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0X6</accession>
    <name>A0A2G4F0X6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55107">
        <property type="protein sequence ID" value="PHX55107"/>
        <property type="gene ID" value="CP500_012595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046002">
        <property type="entry name" value="DUF5958"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19383">
        <property type="entry name" value="DUF5958"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="17339" checksum="540B48A97B3DDC77" modified="2018-01-31" version="1">MNLTDEITINQIQQELISQEDAKNWFLSFPTQGQQEILHRLSYMNIQARAREEDVSLAITQSKLRGTYTPCVLLSKGRLKEQMAKLLKLPSSEFIKTFFLLISLLAIADARRYNKYCQDGCSHWWHRDLSDRKVVDEIRCEFEQSILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F139</accession>
    <name>A0A2G4F139_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55472">
        <property type="protein sequence ID" value="PHX55472"/>
        <property type="gene ID" value="CP500_010625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="7600" checksum="1FC2E5427BCAE7BB" modified="2018-01-31" version="1">MCDRYPSYQDRKQRPVFCALPQAILDFRLAQQNCQLFLVNSTRIKITQKMGLKPRPYRTALIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F171</accession>
    <name>A0A2G4F171_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55524">
        <property type="protein sequence ID" value="PHX55524"/>
        <property type="gene ID" value="CP500_010490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="9192" checksum="7FEB74C61B508953" modified="2018-01-31" version="1">MTVNVKNSFSVLLISGEGIVAGLSVLELLAGKAIELLLLLLSVGLVASSLFENVSVGVGIGIGXLELVLELVLVFVLVLVLELVLVLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1A8</accession>
    <name>A0A2G4F1A8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aldehyde decarbonylase</fullName>
            <shortName evidence="1">AD</shortName>
            <ecNumber evidence="1">4.1.99.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Fatty aldehyde decarbonylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the decarbonylation of fatty aldehydes to alkanes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a long-chain fatty aldehyde + H(+) + 2 NADPH + O2 = a long-chain alkane + formate + H2O + 2 NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:21440"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17176"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:83563"/>
            <dbReference type="EC" id="4.1.99.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <text evidence="1">Binds 2 metal cations per subunit. The catalytic dinuclear metal-binding site could be either a di-iron or a manganese-iron cofactor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde decarbonylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.5" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55535">
        <property type="protein sequence ID" value="PHX55535"/>
        <property type="gene ID" value="CP500_010555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990465">
        <property type="term" value="F:aldehyde oxygenase (deformylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009924">
        <property type="term" value="F:octadecanal decarbonylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00931">
        <property type="entry name" value="Aldeh_decarbonylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022612">
        <property type="entry name" value="Ald_deCOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11266">
        <property type="entry name" value="Ald_deCOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04059">
        <property type="entry name" value="Ald_deCOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="230" mass="25988" checksum="3E667F8D2ECF8A9F" modified="2018-01-31" version="1">MLQLKAIPAIDFQTEAYKDAYSRINAIVIEGEQEAHDNYLTLAELLADEKQELIRLSKMENRHMKGFQACGKNLKVTPDMVFAKEFFSELHENFQKASAEGKVVTCLLIQSLIIECFAIAAYNIYIPVADDFARTITEGVVKEEYMHLNFGEVWLKAHFEESKAELEVANRQNLPIIWRLLNSVADDANVLGMEKEALIEDFMIAYGEALGNIGFSNRDIMRMSAQGLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1D2</accession>
    <name>A0A2G4F1D2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55584">
        <property type="protein sequence ID" value="PHX55584"/>
        <property type="gene ID" value="CP500_010075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="14906" checksum="F42D64656B3DC2B3" modified="2018-01-31" version="1">MRTNRTRSQERILHLLKHLNRSLSAQDIYLELRNSDQSMGLATVYRSLDSLKREGLVHVRTLASGESLYGAAHQDQHHLTCLECGASIPIDECPVHHLESELQQSHSFKIYYHTLEFFGLCDRCTLAQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1R8</accession>
    <name>A0A2G4F1R8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cofac_haem_bdg domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55701">
        <property type="protein sequence ID" value="PHX55701"/>
        <property type="gene ID" value="CP500_009400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14727">
        <property type="entry name" value="ChanN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007314">
        <property type="entry name" value="Cofac_haem-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016773">
        <property type="entry name" value="Fe3_uptake_reg_CjrA_prd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04187">
        <property type="entry name" value="Cofac_haem_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020419">
        <property type="entry name" value="Fe_uptake_reg_CjrA_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013700133" description="Cofac_haem_bdg domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Cofac_haem_bdg" evidence="2">
        <location>
            <begin position="44"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="291" mass="33565" checksum="1BAB438809065006" modified="2018-01-31" version="1">MKKTKLIKLCALSLSIFLLCSSPAKAQPTANPQPAQTYTNQEILQQLLKARIVYLGETHDSIEDHQAQLAIIQEMQRQNRKIAIALEMFQRPFQSVLDQYLAGKLTEEQLIEQTEYNQRWRFPWEYYAPIVRFAKENQLRIIALNTPTEVTRKVAMQGLESLTTEERKHIPPVSEIRTDNAEYRQMLLEVYQQHQKAAQGNSTAFQRFLQAQVLWDETMAEKIAQFVKANPDYQVVVLAGQGHIVYGYGIPSRVERRLGVGKVKMRSVLFNFPTDSPSSADKPIADYVWRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1U6</accession>
    <name>A0A2G4F1U6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hsp70 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_009275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55740">
        <property type="protein sequence ID" value="PHX55740"/>
        <property type="gene ID" value="CP500_009275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="540" mass="60064" checksum="D3C16F37195CC46C" modified="2018-01-31" version="1">MSSYKIGLDFGTTNSIVSYLTPSGDLEAFPYPPPNGEKYVPSFIAYHSDGDTEIGTPARTAAAHDSSVETYGNFKMRLPLKESEFGQYFSGDRTPISVTIDYLRELLISNENDYSFSREKGEIASIVVSVPEIWQRDIRNLGRERLQELIKKDLGLEKQLIQLVSEPVAAAAYYTWETQRRAKAKGTEPFSGNILVCDMGGGTFDVSLCRIYGDKKVEVLYFHGQGDKGLESAGVAFDRRVVQQAYTKKHGKSLDENTADFTSLLKDFESVKIGSHVNATKKLTNYLDDPDDTAQKEAYKFSGYAVTLGEVNEAFAPISQGIKKVINKIIAHTQEQGLAIDRIFLVGGFCQFLLVQKAITDALGIVRNDPRIDQTFNITNSAYAISYGACLIANGLVDPTEKYIHTLGIGLRSIIADQKVQKEITLIEGGSNLDALAKPNFCTESYQTAESQMFVSLWVQINSKGKRHQELMPQNIEVPNHQSGAKYRAGMKVDRSQIAYLAIEEVSTKKCVEYELGNILAKMFPGYVFFDEDEFDDTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Y6</accession>
    <name>A0A2G4F1Y6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55487">
        <property type="protein sequence ID" value="PHX55487"/>
        <property type="gene ID" value="CP500_010285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="26"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="216" mass="24556" checksum="93221C61BA7D3F8E" modified="2018-01-31" version="1">MISVAPIAPPLLIGEKRVVLRNITWQGYQQLLKILGDNRAARLTFDRGILEITMPLEQHEFSRCLIGLLIRILAVELGLKIKTMGSTTLDRSDLNRGAEPDNAYYIQNQPLVAGRTVDLATDPAPDLVVEVDITHTDINKPALYASMGVPEFWRYNGREWRIYQLENAEYLEVSVSPTFPILPKSKLYEFLAAAQLDEVEAEVNFRNWVREMNESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Z6</accession>
    <name>A0A2G4F1Z6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55497">
        <property type="protein sequence ID" value="PHX55497"/>
        <property type="gene ID" value="CP500_010340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="16535" checksum="41449C8D521DBE71" modified="2018-01-31" version="1">MNNQNSDQELVNFLQQYRPTLPEAAPDLELKILAAIDRNEQAGKKQNYWGKVHSIVSNNRLIIPSFRQWAFPPTIVAMLIVFWSGYRLLVPGELNPNEVAHLEAFLVNNWEEVLHDSRENMSDSSKTDWLNFPVSADSEQPTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F237</accession>
    <name>A0A2G4F237_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1350 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55834">
        <property type="protein sequence ID" value="PHX55834"/>
        <property type="gene ID" value="CP500_008760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010765">
        <property type="entry name" value="DUF1350"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34127">
        <property type="entry name" value="PTHR34127"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07082">
        <property type="entry name" value="DUF1350"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="255" mass="28922" checksum="2BEF60B963F238EB" modified="2018-01-31" version="1">MDWQEISGNWVLIPSRPIAIVHFLGGAFVATAPQLTYRWLLEAVANQGYIVVATPFVNTLDHIAIARDVLNKFENALGRLQARESLRSRYLPIYGMGHSMGCKLHLLIGAVFDVERSGNILISFNNYAASEAIPIVEQISPVFNVEFTPSPQDLNRLVQDSYKIRRNLLIKFNGDNIDQTLLLTDLLKQRFSDMITIQTLTGNHQTPLGQDVSWPVGKIFTPFDAIGQWVKQEVYRELNQLKQTILLWLNPMSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F272</accession>
    <name>A0A2G4F272_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Helix-turn-helix domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55842">
        <property type="protein sequence ID" value="PHX55842"/>
        <property type="gene ID" value="CP500_008810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="18302" checksum="263B06AFB9CF3311" modified="2018-01-31" version="1">MPSTNEQFTQAANHWDLETLYIDLSSAKGKRLTPVEKLHLRGLLCGYSPAEIAEKLHKSVKGVESEVCTTLYPHVKSLVGKSNEKMENWRNITEWLQEAGYKTQSSTESQLKNCVPVDIIGKIANISIKKNRITIEIDLQQTDKLPSETPTEDLNNNNYTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2D9</accession>
    <name>A0A2G4F2D9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Glutaminase</fullName>
            <ecNumber evidence="3 5">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">glsA</name>
        <name evidence="6" type="ORF">CP500_008060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glutaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="3 5"/>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55920">
        <property type="protein sequence ID" value="PHX55920"/>
        <property type="gene ID" value="CP500_008060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00313">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015868">
        <property type="entry name" value="Glutaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12544">
        <property type="entry name" value="PTHR12544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04960">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03814">
        <property type="entry name" value="Gln_ase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="304" mass="32865" checksum="CB2828A4E84C0479" modified="2018-01-31" version="1">MPAISRLQPEQLEIWTAQAINRSLSGQMPAYIPLLVQADRQKFAVQIRAIDGGFLGLGNADQIFPLMSVVKPFVLLYLLCELGEIAVFEKVGWEPSELPFNSLTQLQIDQGQPRNPMINSGAIALASLIPGENAVIRCQNLFHWLNQQAESELFVDELMLDSVKANPNQNNGNLALEMVKSGVIQDAEIALATYNRVCCLSGTVEDLAKLGMLLVNRGDRTISEHGRTVKALMATCGLYEASGRFAVRVGLPTKSGVSGAVLSVIPGQGAIACYSPPLDKEGNSVGGLFLLEQIAKSLRLSVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2L3</accession>
    <name>A0A2G4F2L3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LD-carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_009375</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55697">
        <property type="protein sequence ID" value="PHX55697"/>
        <property type="gene ID" value="CP500_009375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S66" evidence="4">
        <location>
            <begin position="48"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="5">
        <location>
            <begin position="208"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR028757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="339" mass="37443" checksum="BC8C4F6D9FB7911E" modified="2018-01-31" version="1">MVIPRRYLIRTFGLTAIGTQLLPIAQSQILPQSQTTILPRRLQIGDTIALINPAAFTYEKEIQPFFKAAAQLGLKVKLGKHFYDRYGYLAGKDADRAADVNTAFADSSVQAIFTGMGGWGCGRILPLLDYNMIRNNPKIIIGFSDVTALLLAIHTKTNLVTFHGPLGVSNWSSFTVDYLKQVLFDAGAVTLQNPPKMDIETIREGKARGKLIGGNLSVISTMIGSAYLPDWENSILFIEEVSEEVYRIDRMLTQLKLAGILDKLSGFIFGQCTRCDAEKPQESLTLTQVLSDYIRPLMIPAWYGSAIGHIRDKFTLPIGQEVEIDANSGTIRLLESAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2M3</accession>
    <name>A0A2G4F2M3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4926 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55998">
        <property type="protein sequence ID" value="PHX55998"/>
        <property type="gene ID" value="CP500_007810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032568">
        <property type="entry name" value="DUF4926"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16277">
        <property type="entry name" value="DUF4926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="8931" checksum="15E86E9B02F487E4" modified="2018-01-31" version="1">MNYQLYSDVILLCNLPEEGLDADDIGTVVEQHHVEGLETGYSLEFFDLLGNTVAVATLPGSYLRSPTSADRPTVRLVNSFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2N5</accession>
    <name>A0A2G4F2N5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56016">
        <property type="protein sequence ID" value="PHX56016"/>
        <property type="gene ID" value="CP500_007630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8228" checksum="5003803F51DA31F6" modified="2018-01-31" version="1">MNSCPCCSSQLLRHARHNRLYWFCSHCWQEMPDLSEMILGDRQRNRKLDSLVKVSALMPKLTVLEPLRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Q5</accession>
    <name>A0A2G4F2Q5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="2">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">clpP</name>
        <name evidence="4" type="ORF">CP500_007700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56028">
        <property type="protein sequence ID" value="PHX56028"/>
        <property type="gene ID" value="CP500_007700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="218" mass="23872" checksum="0FBA9C5B99BDFCD2" modified="2018-01-31" version="1">MNTPIKAVQSQYYGEGNSRTPPPDLPSLLLKERIVYLGMPLVPAVTELIIAELLFLQYEDPDKPIKIYINSTGTSGYSGEPVGFETEAFAICDTIRYIKPPVHTICLGSAMGMAAMLLAAGTKGFRASLPHASIVLHQPRAYTRGQATDIQIRAKEVLANKATMLEIFANCTGQPIDKITKDMDRLLYMTPQEAKEYGLIDRVLESSEELAKPLAAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Q8</accession>
    <name>A0A2G4F2Q8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56036">
        <property type="protein sequence ID" value="PHX56036"/>
        <property type="gene ID" value="CP500_007750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="11051" checksum="E309CDED1608BF30" modified="2018-01-31" version="1">MSSTNFKPFRSDDYPEMERDVIQERLRQAKFSFNVTIGLAIVSASISILGIGMLFSGKISEGSVATAGGLASNVVSVGLLKFTKETNDRLDRLAKEFKDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2R5</accession>
    <name>A0A2G4F2R5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="3">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_007535</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006633295.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56042">
        <property type="protein sequence ID" value="PHX56042"/>
        <property type="gene ID" value="CP500_007535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024605">
        <property type="entry name" value="NADP_transhyd_a_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12769">
        <property type="entry name" value="PNTB_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="PNTB_4TM" evidence="11">
        <location>
            <begin position="9"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX56042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="9955" checksum="97E52E5912F23CFB" modified="2018-01-31" version="1">MAEGLIAGLVVFTLASFVGFEVINKVPPTLHTPLMSGSNAISGIAVLGAILISGQGNVTVTSILGTIAIALATINVVGGFLVTDRMLQMFKKKEVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F318</accession>
    <name>A0A2G4F318_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ychF</name>
        <name evidence="7" type="ORF">CP500_006825</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56152">
        <property type="protein sequence ID" value="PHX56152"/>
        <property type="gene ID" value="CP500_006825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="2"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="130"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="363" mass="39439" checksum="1DF181916F0AF5C1" modified="2018-01-31" version="1">MLTAGIVGLPNVGKSTLFNALVANAKATAANFPFCTIEPNTGIVAVPDDRLQVLSDICNSAQTVPTRMEFVDIAGLVKGASQGEGLGNQFLSHIRAVDAIAHVVRCFDNDDIIHVAGSVDPVRDIDIINLELILADLAQIERRLDRTRKQARNNKEAQAEVDILEKLVAVLNAGKPARQYSFTDEEAELVKGLELLTNKPIIYAANVSEDDLGTGNSYVEQVREIAEAENAKVVIVSAQVESELVELPEEERLDFLESLGVTEGGLKSLIRATYELLGLRTYFTSGPKETRAWTIIAGMLAPQAAGVIHSDFERGFIRAETVAYQDLVTTGAMNAAKEKGLVRSEGKEYVVQEGDVLLFRFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F335</accession>
    <name>A0A2G4F335_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56171">
        <property type="protein sequence ID" value="PHX56171"/>
        <property type="gene ID" value="CP500_006925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="SSF50199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNase-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="33354" checksum="EC585B6745CA4C72" modified="2018-01-31" version="1">MATRIQNLQITQVVDGDTVKVALHGKIESLRLICVDTEESYSGGSKPVTVAGKEASEMAKQYFATEDGGLAKVDIEFDTNDPIAVSVEKHRDNYGRLLCYVHKGEENYNLKLIQEGWSPYFLKYGRSRLYHRSMTEAETVAKAYNLVIWNPNTNAKVPSRNYGHLLPWWSMRGSIVEEFRLSQATGGAFSLRLDYPKILAASETAQSITVFCDLQGGINKWIGNNALIHAGSVYHKLDLWIPDAESDKMTPLKQLIDKHYAGLGRGYVYVSGKVEEYKGKPQIVLKDIKQLSDFPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3A7</accession>
    <name>A0A2G4F3A7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55957">
        <property type="protein sequence ID" value="PHX55957"/>
        <property type="gene ID" value="CP500_007880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14679" checksum="B3FAB702518E474B" modified="2018-01-31" version="1">MLEQCVEVKCPIQFVLDLLDNKWSILVLRELFGGARRTHELLAALPGISTKSLTQRLRELEAQGLVDRRVYAEIPPRVEYSLTPKGHQIQPVMAALHQVGSQWLGQESCVCPLINSDVRDDRMDASGLVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3B2</accession>
    <name>A0A2G4F3B2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PAS domain-containing sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_006410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56238">
        <property type="protein sequence ID" value="PHX56238"/>
        <property type="gene ID" value="CP500_006410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="360"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="430"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="719"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="675"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="693"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="840" mass="93738" checksum="2A519C8D7155FC34" modified="2018-01-31" version="1">MKKETRFHKRKIFQQLLGGFALSLIVISIATLSITSASLRHNLEEQIQQRAESITYGIEFASEGLIEIKEMLLLERIVQNYATLPAVIEVSIVDPQGILLAHSNEFALNAIEDRHYAKLHPTLALTWEQVSEQGIDKNIHTVLHGKTVVVQMLPFSSTLFNQVGVGSPADRKHRGVAIAVMDLQKMEQDALQSALSSILTMAVSALLILVFMSWLIRRLVLSPLEKINLAIIQSEGQDVFYLPTLPNNEISFLGVTFAAVFQELKAYKQMELEIVERKYAQVAQRYELATRAAKVWVWDLDLKTNIFILDQGIQEWLSYENDEFSNNFHLKTWVNYIYIDDRPLFLQALQAHLEEKTSEFYCEHRLLKADGTTHWFLSRGQVVKNKHGTSVRAIGTITDIADRKQYEAQLHATNQELIRATRLKDEFLANMSHELRTPLNAILGMSEGLQEQVFGSINEPQIKALQTIERSGSHLLELINDILDVAKIESGQMELDCTPVSVNHLCQSSLAFIKEQALQKRIQLEIKVPLNLPDLLIDERRMRQVLINLLNNAVKFTPNGGRITLEVSRQQRRADPDSADSPPQFLVKDILRIAVIDTGIGIASEDINKLFQPFIQIDSALNRQYQGTGLGLALVKRIVELHGGRVLLTSEVGVGSCFAIEFEGRHGGIEFEGRHGGIEFEGRHGGTAPTGAPSSVDLESQTEPRIEPSGPKQQEGSPLILLAEDNEANISTVSSYLKAKGYRILLAKNGEEAIALAKSENPNLILMDIQMPGMDGLEAMQQIRLDPSLVDLPIIALTALAMTGDRDHCLAAGANDYLSKPVKLKQLAATIQHLLTSLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3D8</accession>
    <name>A0A2G4F3D8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56258">
        <property type="protein sequence ID" value="PHX56258"/>
        <property type="gene ID" value="CP500_006215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPt" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="329" mass="35114" checksum="43D66A43DA56D9DE" modified="2018-01-31" version="1">MSDQQDRILRLFMEEAKEHLDTLENGLVDLKSTMKDPENIKEMFRAAHSVKGGAAMLGLDSITTTAHRLEDCFKILKDGPVKQVDQTAESLFLKGVDTLKDLVQRMSGPFGLRNEEGEKLVEQIMPTFAQLETHLNNLVSGKVAGAAAKSGSSGAASAVGGTTNFAASVMVLLKEMLQVFKQKESAATRQQLSDVCVRLYKLGTGVESWQGLVKTARVAIANPENSYKVLAPLIIKELKDAGDLVQGGKVKAIAPSKNLLLLARPVQAATSVPATAPATAPATTPAAASQPVALPSEPKAVVKLLLKTFNKKQLSEIAKLLIHAIKSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3M3</accession>
    <name>A0A2G4F3M3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56384">
        <property type="protein sequence ID" value="PHX56384"/>
        <property type="gene ID" value="CP500_005575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="204" mass="22288" checksum="C5032D273AE16308" modified="2018-01-31" version="1">MQLLRKRYREGFMIDTKSLQFGTIAEFETPCRSMDLKGKDIVVATPDRSAGGAESRMTGVAPHCVRLALQELKCFEVVEHQFRYWGLTFTNVVAIQPSNPAFLTASGTTILMGAPKSGQIEVSFKYPVRFVSGLVTSSRRTVLSACDADGIQIAQDEMPGPNLVGSSSPIDPSTELCVKAPNISKVTFYAFDGQLVVHDLIFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3M7</accession>
    <name>A0A2G4F3M7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56383">
        <property type="protein sequence ID" value="PHX56383"/>
        <property type="gene ID" value="CP500_005565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10080" checksum="3B26F99797E5AE27" modified="2018-01-31" version="1">MPGANFPGHCRRQESSIAITIINIFLINYYIFDPHLIWQLAIFSIALFLVSVILNFVLLSCSPLASISCTIEFKVSIYPLSWSMLKTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3T4</accession>
    <name>A0A2G4F3T4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56395">
        <property type="protein sequence ID" value="PHX56395"/>
        <property type="gene ID" value="CP500_005640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7832" checksum="788EF875C66BC8E2" modified="2018-01-31" version="1">MKSEYDFSASEQGKFYHPDATFHYPIYLEADVEQFVTKIAEHKNIDVQVLVNEWLRNNIKLIQSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3V7</accession>
    <name>A0A2G4F3V7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56442">
        <property type="protein sequence ID" value="PHX56442"/>
        <property type="gene ID" value="CP500_005420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="159"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="559"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="476"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="701" mass="79394" checksum="CFD951C644EFECA5" modified="2018-01-31" version="1">MFSDNEMLPKLSLHTHSRSMKNILNKLLSLRRIEYLAVDRELKIQETSLNVQEFADIPDEFEKGKDVRDSFPELIGIEEILDDILEEKQPDFQLKSITRVLNDGSYLYLDLYIFGCKYKLKPERLIIFCEDVTDSTNLQQSMVQSVNENSIKVNSLSTSHDYIEEILNSINDILLVTTASGKIKKVNKSTQLLFGYTELELIGKPISMITPNEDLLRQVSQLPTELKNELWHQVKVICHTKKGLNLTVAFSCSTIKTRIESKHLETKTLQDFVYIGRDITEQQRTKKRQAAQYAVAHIMSESGSLESATPKILQAICESLGWDVGELWTPVDEKEAKFDADNQRGKVRFLFATPDASVEEVPFMLRVGVWWRGNEVGEFVENCQQIILDPGEGLPGVVWNTGFPQWITDIFKDGNFRRSHLAAKTGLTSAFGFPIRASGQIVGVMTFFCRIKQPSDEDLLQMMAAVGSQLGQFVKRKYAEKELQEAEASIRSLYEEEKRQSQKLVQQNVALEQTKLELESANRALQRLASVDGLTQIANRRCFDKTLHSEWQRMARNQEPISLILLDLDFFKLYNDHYGHQRGDECLKKIAQILARNAQRGGDLSARYGGEEFAVILSQTEAEGAMRVAESISRDLKAQAIPHALSKVNQCVSASIGIASTVPNPGLSVEWLIGEADRALYQAKLEGRDRIIYLNPLNFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3W3</accession>
    <name>A0A2G4F3W3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein L11 methyltransferase</fullName>
            <shortName evidence="2">L11 Mtase</shortName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prmA</name>
        <name evidence="3" type="ORF">CP500_005375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Methylates ribosomal protein L11.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13826"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56436">
        <property type="protein sequence ID" value="PHX56436"/>
        <property type="gene ID" value="CP500_005375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00735">
        <property type="entry name" value="Methyltr_PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004498">
        <property type="entry name" value="Ribosomal_PrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000401">
        <property type="entry name" value="RPL11_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00406">
        <property type="entry name" value="prmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="296" mass="33212" checksum="B4DB581D9241D3C3" modified="2018-01-31" version="1">MAHSWWEIRVLCDPALEDIIFWRLEMFGCQGSVSQMKSNSCLMSAYLPEEKAGLLDLAALSLWLRQDALCAGLPLPAMQWDLIEEEDWGTTWKQHWQPQEIGDRFLVYPAWLPIPSNPDRLILRLDPGVAFGTGAHATTQLCLESLEMRLGFDDKKYVLADIGCGSGILSIGAVLLGATKVYALDTDPLAVRSTISNRQLNRVNPQQLVSELGSIDRLKELVDEPLDGFMCNILAEVIIDLIPQFTEISKPTTWAVLSGILVDQAKPIADTLEQNGWIVATLWKRQDWCCFNIRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Y9</accession>
    <name>A0A2G4F3Y9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="2">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_005510</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56458">
        <property type="protein sequence ID" value="PHX56458"/>
        <property type="gene ID" value="CP500_005510"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="3">
        <location>
            <begin position="9"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="ApbA_C" evidence="4">
        <location>
            <begin position="186"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="324" mass="36610" checksum="DF6D18B578E1A7F1" modified="2018-01-31" version="1">MPNRNRNYAIVGTGAVGGFYGAKLQKAGLEVNFLLRSDYEHVKKHGLIVESPEGDFTLPQVRGYHDSRKMPKFDVVIVGLKTTQNHFLPKILPDLLKDNGVVLVLQNGLNIETEIAKIVGAERVIGGLCFLCSYKVSPGHICHLDYGTITLGEYTEDYKYIGITNRLHQIANDFKSAEIPINLSADLLLSRWKKLVWNIPYNGLSVVLNARTDELMANPDTLILVEQIMREVVAGAKSCDRIIPDEFIPHMLDHTHKMKPYRTSMKIDYDESRPLELEAIFGNPIRAAEQAGIKLPQIEVLYRMLKFVDAENQEAERKRQLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F428</accession>
    <name>A0A2G4F428_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56512">
        <property type="protein sequence ID" value="PHX56512"/>
        <property type="gene ID" value="CP500_004980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039476">
        <property type="entry name" value="P2CMN_synthase_LarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43064">
        <property type="entry name" value="PTHR43064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="1">
        <location>
            <begin position="121"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="257" mass="27017" checksum="AF7D786B9AADC266" modified="2018-01-31" version="1">MEPEILQKLLESVAAGDISPATALDKLKHFDFEQVGDFAKIDHHRKLRTGFPEVIWGPGKTPDQIVEIIQAMRGRNPAVMATRIEPEVFEQLQQKIPDLCYYQKARICAISASSPTSQHPGKVTIISAGTADLGVAEEAAVTAELCGFQVQRLRDVGVAGIHRLLSNRHVIDDADVLIAVAGMEGALASVVAGLADCPVIAVPTSVGYGASFGGIAPLLTMLNSCAAGVGVVNIDNGFGAAILACQILRTAGKVGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4E4</accession>
    <name>A0A2G4F4E4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_004510</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56619">
        <property type="protein sequence ID" value="PHX56619"/>
        <property type="gene ID" value="CP500_004510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="11"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="113"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="217"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="251"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="285"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="319"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="402"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="732"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="766"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="800"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="834"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="868"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="902"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="435"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1363" mass="153997" checksum="CB24B15ADB7351FC" modified="2018-01-31" version="1">MRLMEKMEKAAVDLSQQAEVYLAEGRLNEAVAACESALRIQPNLATACQTLGKVMEVRGEIEQAKQWYEAAIDRDPNLPEVYANLGSLYSQLKQWEKAIAACEKAISLSPNFAEAYRQLGRVWTQLQKRETATECWYQAFKIEPNWATAEEYVSLGNHLVEQEKFDRAIECYSQAIQIDPTFSIAYHNLGEMLFREKRWEDAIANYRKAIEINPNAFESYHGLGKTWAVQGELDRAIACHRKSIEINPNYARACLSLGNVLVQKGEFDTAINCYHQAININGNSAWAYNYLGEALAQKKLWQESIICYHKAIELNPSIPWFYINLGIALTCEKSWNQAVAAYLHAIQLQPNLTGINQRLGYVLRKLSESSLDNTILSYCQGIEVLANGKTYHKLLGIELDGMEFYLNLGNSLANQKQLEGAIVFYSMALQIEPNAAEVVAKLDEARRKQQELYAQIASYRHKIAIAPNDSQAYNDLGNILPQLGELEEAIVCHQKASELRGWVECATKDYQFTQDWFTHNIPIWKRHLQQFKGMPEFQVVEIGSFQGMSACWLLDNILTHPTAKITCIDLYFQQDFKGNIVKTGVAEQVIELEGYSQDLLVNLTSEYYDIAYVDGCHKPTSVLQDAILSWRLVKVGGLMIFDDYEFTFPDSPEQDTKIGINLFLEMFASQLEVVHQGYQLIVKKTDNKKLGEEQALLSQGWEKLGDIAANTGYADEAIARYQTAIKIKSGTYSLYHKLGKVLQKKELFDEALSAYRQAIQLNPNFSWAYHYLGETLQAIEEYADAATAYHKAIELNPDFCWTYSSLGDVLMELAQLEEAAVAYRKVIELNPDFCWAYDKLGKALIAVENWGEAEVAYRKAVELNPEFCWLYNSLGEVLEEQEKWPEAAAAFRRAVDLSPDTIWLYKKLGDALRKQGELESAIAIYEKGINLEPKSCWCYEGLGLTLIAKQQWEPAITHLVQALQIQPDLFEVYDNIGYALEQQGEVDESDRAKCSNQILPLSVLQKYCGFTEDLAIAAESNPNITCIDIYPASQINLLASKTTDSSNRFWANQTHTRKAFVAILPKGRAWADVVTTAVITSDNKLVGDISMGCAELVITSDKLPPIEHIDGNVAFLSARWGGAAYFHWMFDVMTRFDLLQRSGLIESIDKFVVNACDSAYQKETLNTLGIPEHKILESRCNLHITADKLIVPSISYDGAGAVSKWKCDYLKQAFLTEQQPIKSDYSERIYISREQASYRRIVNDKEVMSFLEKFGFRSVQLETMSVAEQAACLAAAKVVISPHGAGLTNLVFCSPGTKIIEIFSPIYVPSCYWMISNLCGLEHYYLIGDLFDDGIIKKPVHKNMQLDLKSLEKLMNLAGVLHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4G5</accession>
    <name>A0A2G4F4G5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56601">
        <property type="protein sequence ID" value="PHX56601"/>
        <property type="gene ID" value="CP500_004500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="31"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="213" mass="24930" checksum="F4872B30847E4031" modified="2018-01-31" version="1">MLTIELDTLLKEQALQRQDPEERYITDRVNWEEYETLLERIGDAAGYRVTYLDGVLEIMSPSRRHENGKSRIGNLLEIYFVEADIEYFPFGSTTLRQEEKSGGTEPDEAYCIGTDKEFPDLVIEVIVTSGSINKLELYRRLNVPEVWFWRNDRFSIYHLREEIPVEFVSNWGYELIQNSELLPELDIEMLTECVKNPHPLAAAKAWRQNLLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4J0</accession>
    <name>A0A2G4F4J0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GFA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_004275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56658">
        <property type="protein sequence ID" value="PHX56658"/>
        <property type="gene ID" value="CP500_004275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="8"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14856" checksum="136A6C0379FE7C88" modified="2018-01-31" version="1">MDHTLVMYEGGCHCGAVRFRVAVDKHEAADCNCSICHKKGFLHLIVPPEHFTLLSGEDVLTTYTFNTGIAKHTFCGICGIHPFYRPRSHPDQFDVNVRCLDSDAIAQFRIVPFDGVNWEQNVHLLRDENNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4M1</accession>
    <name>A0A2G4F4M1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fic family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_005385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56437">
        <property type="protein sequence ID" value="PHX56437"/>
        <property type="gene ID" value="CP500_005385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025758">
        <property type="entry name" value="Fic/DOC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026287">
        <property type="entry name" value="SoFic-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13784">
        <property type="entry name" value="Fic_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038925">
        <property type="entry name" value="AMP-prot_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="112"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="198"/>
            <end position="205"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="199"/>
            <end position="205"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="236"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR038925-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="362" mass="41547" checksum="14EF0490753251D6" modified="2018-01-31" version="1">MTTSYSLPLLPGDIEDIENKVVLKKLANAHRALAELKGVANSIPNQAILINTLSLQEAKDSSEIENIITTQDDLYRSDSEVKQFVTVAAKEVHNYATALREGFEAVQKSGLLTKSQILRIHATIEGNNAGFRKLPGTTLKNDATGQVIYTPPQNYEEITSLMDNLEKFINDDTICDWDSLTKMAIIHHQFESIHPFYDGNGRTGRIINVLYLVKQDLLKIPVLYLSRYINQTKATYYQLLQRTREIKDWSSWLLYILEGVEQTSLETIDLIEAIKSMMQSQKHLMREGLPKIYSQDLLNNLFRHPYTKIDFVMKELSVSRITATKYLDELVRIGLLKKHRIGRDNYYVNFKLYDLLANISQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4X7</accession>
    <name>A0A2G4F4X7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucokinase</fullName>
            <ecNumber evidence="1">2.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glucose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glk</name>
        <name evidence="3" type="ORF">CP500_004675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17825"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the bacterial glucokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.2" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56547">
        <property type="protein sequence ID" value="PHX56547"/>
        <property type="gene ID" value="CP500_004675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00524">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003836">
        <property type="entry name" value="Glucokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02685">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00749">
        <property type="entry name" value="glk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="346" mass="37170" checksum="60006FF871EF6884" modified="2018-01-31" version="1">MALLLAGDIGGTKTILRLVERTVEGEMNSLYEFRYPSGEFPDLVPMVQQFLTATAVKLDFAPLPEKACFAIAGPVVNNTAKLTNLSWRLDAKRLEQELGISHVSLINDFVAVGYGVCGLDATDLHTLQVGKPREEAPIAVIGAGTGLGYCFAIPEANGVKVFASEGGHGDFAPRSELEFQLQKYLLAKHDIARISIERVVSGQGIVAIYQFLRDTKFAPESAEVGEIIKQWESEVGKTEKTVDPGATIAMAALKKCDRLSEQTMQIFVEAYGAVAGNMAVTLLPYSGLYIAGGIAAKILPLIQEGSFMRAFTHKGRMDSLLEMIPVHVVLNDNVGLIGAAVCAIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F533</accession>
    <name>A0A2G4F533_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56882">
        <property type="protein sequence ID" value="PHX56882"/>
        <property type="gene ID" value="CP500_003145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="174" mass="19750" checksum="2FA99E68DA94564B" modified="2018-01-31" version="1">MAWVFSLSAECGTKQSEAEQFAQYFNQISWTISNGTHSQCRAEIFQDIEENWWCRVCPSGISEIGIDTPESAYLMTEIGIFLYHSLRFAPPFRYALVGMEVDEFRTYSELIEESALVFPGLVLAEAVWQATGSDSVFRSFSLGYVWKPYEGEVYRPLIASPDLKNKLDELLSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F551</accession>
    <name>A0A2G4F551_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56876">
        <property type="protein sequence ID" value="PHX56876"/>
        <property type="gene ID" value="CP500_003115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="26268" checksum="9C2DB66E71A7CF5D" modified="2018-01-31" version="1">MCEFEHLTSQIINNFGSELVAVLGYGSRINNRKAVDAFSDYDITVVFSDYPNNHFPDLPIYADVTMVFLSEIELTGVELFRLDGHGAYYLYVLAHAVALYGSNPFSNFAARLDTDSVNMSLREQIVAYCWKLQRIVIQPQTNRKWRDIRKYSLRMAQNYYFLVKGICCEVFWDLSYVECVAELCKVLILEDKFASYLIKSAQYPERLEIKEVLEYAALLKAKVAIKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5H2</accession>
    <name>A0A2G4F5H2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ORF">CP500_003705</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56727">
        <property type="protein sequence ID" value="PHX56727"/>
        <property type="gene ID" value="CP500_003705"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="149"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="182"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="204"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX56727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="233" mass="25237" checksum="3518CD00FC8C49A5" modified="2018-01-31" version="1">MTKSQKPIVIAPSILSADFSRLGAEIQAVDQAGADWIHVDVMDGRFVPNITIGPLIVEAIRPVTTKIIDVHLMIVEPEKYVEDFAKAGADIISVHAEHNASPHLHRTLGQIRELGKKAGVVLNPSTPLELIEYVLELCDLVLIMSVNPGFGGQSFIPTVLPKIRQLRQMCDERGLDPWIEVDGGLKVDNTWQVLEAGANAIVAGSAVFKAKDYAGAIEGIRNSKRPTPQLAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5M6</accession>
    <name>A0A2G4F5M6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57025">
        <property type="protein sequence ID" value="PHX57025"/>
        <property type="gene ID" value="CP500_002220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019275">
        <property type="entry name" value="DUF2301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36716">
        <property type="entry name" value="PTHR36716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10063">
        <property type="entry name" value="DUF2301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="215" mass="23818" checksum="571E7D87E000A668" modified="2018-01-31" version="1">MQLLKSPDESPVYQGQFGEFTITQSDRTGVIIYRTGLGVAAACFAIGTTLVLQQGDNPTAIQAITPIFACFWIALGVSLATIHIYMIALHRLLQLFWAIGGAAALFVTIQSTEPLALAVYEHPATLWGIGFLFAALNGIYFKEAFCFNRLETKFLTPGVPLLILGHIWGFFTLENKQLLLASWAVLFIIFAVRKLFQPIPQDIGDKSVFEYIKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5P4</accession>
    <name>A0A2G4F5P4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56797">
        <property type="protein sequence ID" value="PHX56797"/>
        <property type="gene ID" value="CP500_003465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="8820" checksum="9684799A7B57BAE1" modified="2018-01-31" version="1">MIPINEAQQQLQQLIDSVSESHQPIVIAGQTSNAVLLSESDWASVARETLYLLSVPGMRESIREGLATPIEECDRQLQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Z1</accession>
    <name>A0A2G4F5Z1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_001405</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57204">
        <property type="protein sequence ID" value="PHX57204"/>
        <property type="gene ID" value="CP500_001405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014905">
        <property type="entry name" value="HIRAN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00910">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIRAN" evidence="3">
        <location>
            <begin position="128"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="254" mass="29514" checksum="995AA34D6DF26876" modified="2018-01-31" version="1">MKTPKTLFLAWKDPISPNWFTIGRLTFDRNIYQFVYTQGVKEAEEKCAFTPLLSFPRLDEVYTSTYLFPVFANRVMSRSRPDYSSFIEQLDLLNDDPSPMAILARSGGERVTDTFAVFPDPEVDEKGRYNLYFFSQGLRHLPRSAIDRSERLEAGETLEFDREVQNPYVDLVLISNTSDRSIVGYFPRYLLAEVFELLRQNSNLEVRVERVNKPPTPLQFRLLCKMSVHCRDDFRLFSSFQYQPAIAEIAVKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F633</accession>
    <name>A0A2G4F633_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HEPN_MAE_28990 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56947">
        <property type="protein sequence ID" value="PHX56947"/>
        <property type="gene ID" value="CP500_002925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040788">
        <property type="entry name" value="HEPN_MAE_28990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18737">
        <property type="entry name" value="HEPN_MAE_28990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN_MAE_28990" evidence="1">
        <location>
            <begin position="6"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="230" mass="26716" checksum="3712099B1BB7A653" modified="2018-01-31" version="1">METVLFDFNTRTKEVHDYFIFVESLEKQTIKLAVFDSVGTYKIQSLNPELAKTLKSNIFLLLYNLVESTMRNAIEAIFDELKNKAISFDDLKPKIKMIVLQNLKNRSPKKIHLTINQISTDIITATFEREELFSGNVDARLIKEIAENYGFSYQTDFTKTKNGQNLVVVKRNRNDLAHGIKSFEELGHDQAIEELLEIKEEVVEYLTQILENIRDYLDNEEYLELPTSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F636</accession>
    <name>A0A2G4F636_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57185">
        <property type="protein sequence ID" value="PHX57185"/>
        <property type="gene ID" value="CP500_001270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="298" mass="32694" checksum="E950A205BB87613C" modified="2018-01-31" version="1">MLTLRTLFDRKFYLENNPDVAVAVARGTVSSPFDHYQKIGQFENRDPNSLFDASYYLETNTDVAVSAQKNKFAGAEHFIAYGQFERRSPNPLFDVNFYLSSNPDVQRVVQTNQVTAFEHFLRIGQTEIRKPSPFFDPEFYLNKYPLVAAAVRNGVVKSAIEHYIQFGQAEGLLGTLPDIADDLTGATNLDVLTGTQNVDNSVSAAEPTDIYSFILNTPSLFSATLDGFSADIDLELIQDINGNGAVGVSEIIASSNNLGTASEQIVSNGVLPAGTYFVRVSQFEGDTNYNLRLTSAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F694</accession>
    <name>A0A2G4F694_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_001115</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57269">
        <property type="protein sequence ID" value="PHX57269"/>
        <property type="gene ID" value="CP500_001115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX57269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="480" mass="53785" checksum="3A9D9F55AF6FFA0D" modified="2018-01-31" version="1">MDILSNTLALSRMQFALTAIFHMLWPVLTTGMGIYLVIVEGMWLKTRNPDYYHHARFWSKLYVLNFGIGVASGIPMEFQFGTNWAPFSEAVGDFFGSILGFEASMAFMLEAGFLGIMLFGWERVHPIVHYFATIMVAFGANLSTVWILVANSWLQTPAGGEMVNGKFIVSDYFQAIMNPFALNSILHMFFATLETSLFVIGGISAWYILNKRNESFFSKSLKIAIATAIAVAPLQIFIGHLSAEQVYHYQPTKLAAIEAKWETSPAGSSADWTLMALPNEKAQKNDWEITVPNGLGYVLEFKQKLSEPVLGLKEWKPEDRPRMVGLIYYSFRIMSGIGFFFVGLMLFSIIQWSRGKLSAENISTQPWLMRAWILAAPLGYIAVESGWIVRCVGRQPWALYGQIRTADAVSNIPASNVLTSLSFFAVVYSFLFICALYFGSRIIRKGPNLNLPIPGLDNQPAIETEPAEHIPDRRPAEAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6D8</accession>
    <name>A0A2G4F6D8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57285">
        <property type="protein sequence ID" value="PHX57285"/>
        <property type="gene ID" value="CP500_001200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="90" mass="10410" checksum="4C5B328746C13008" modified="2018-01-31" version="1">MDFLNAESRKIFSVFLDLLPNCKLLFCTILENRQDACSTTQKPALRPVPQLKNRLSGLFHKECIFLWDVGLGILPADQRPNEMCDRLFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6L8</accession>
    <name>A0A2G4F6L8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NYN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57389">
        <property type="protein sequence ID" value="PHX57389"/>
        <property type="gene ID" value="CP500_000155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="6"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="176" mass="20179" checksum="5C7F484F4C2D2510" modified="2018-01-31" version="1">MNGLHLFIDNSNIFIEAQRVARNQYFYDDELVIRVRISYGGLLEEIRKGRKLAETVLVGSKPPKNDSFWNQLKTFGIEPRTFDRSTFTGKEKRVDAELTNAIRDTLEDNPTPGTIAIVTGDQDQIPALERCVKKGWAVEIYFWGQASNALKNFEGANFINLDRSFEKITFLEKARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6M4</accession>
    <name>A0A2G4F6M4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57406">
        <property type="protein sequence ID" value="PHX57406"/>
        <property type="gene ID" value="CP500_000250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="17"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="146" mass="17338" checksum="3FEA1E9D0E51B0F8" modified="2018-01-31" version="1">MKDQQPKTELHLQVETDMGALKQVEEWLEKIVLPLLPEDWSWQCSLIVNEGFTNAVRHAHKNLHPTTPIDLEVKVFPNYLEIRIWDRGQPFDLEAKLHSIIQDQRDPLEKESERGLLFMHKLTEELRYIRTDDRRNCLVMRKNITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Q0</accession>
    <name>A0A2G4F6Q0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_000395</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57430">
        <property type="protein sequence ID" value="PHX57430"/>
        <property type="gene ID" value="CP500_000395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="3"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="221" mass="24890" checksum="F397F8BD958777E9" modified="2018-01-31" version="1">MTIADRIATIRQQLPDSVRLIAVTKQVPTDAIREAYDAGIRDFGESKIQETAEKQSQLQDLPDINWHLIGHLQTNKAAKALEQFQWIHSLDNLKLATRLDRLAGELSFSPQVCLQVKILSDPDKYGWSVPELLADLPELNRCQYIKIQGLMTIPPRGLDDSQLLEFFNSTRELADKIQQQNLPHIQMQQLSMGMSGDYHLAIQAGATMIRLGQSLFGSRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Z9</accession>
    <name>A0A2G4F6Z9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Two-component sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000025</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57367">
        <property type="protein sequence ID" value="PHX57367"/>
        <property type="gene ID" value="CP500_000025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="227"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="443" mass="49767" checksum="1602EA76B91AC80C" modified="2018-01-31" version="1">MHSNKLFNRTRWQLAGWYAIVTGLLLGICGVAVYQVVFHTQRYILQQKLQDLAGTLHDTIEPELQQPGQVSSSFKTILPGLCLSNENCYSSDNEGARHTARVFQQEGYYLRFLDQSGRILGMIGDQPDVLENLTTKEFWQVLYLSNGDRFYQISLLLRTNSGLPWGYLQIGRSLKEWDAYLNTLRLLLFLGLPFAMLLVGGASWWLAGVAMRPIYQSYRQMQQFTSDAAHELRTPLAVIQTTVEDTRLAEDLPEVNQNLDIIERQNIRLSRLVKDLLFICRIEQQQISTQLQPCSLNDLIGDLVEELAGLAMIAEVHLKLEIRASQATMILGDEVQLYRMVTNLITNAIHYTPPGGLIIAILDRTDKEAVIQVQDTGVGIASTEQTRIFDRFYRVQSDRSRATGGAGLGLSIASAIAHAHQGSIQLQSELGKGSTFTIRLPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUJ7</accession>
    <name>A0A2G4EUJ7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_022690</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the MIP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000241">
        <property type="protein sequence ID" value="PHX53213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53213">
        <property type="protein sequence ID" value="PHX53213"/>
        <property type="gene ID" value="CP500_022690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="6">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="108"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="356" mass="37599" checksum="66DF8A0972C1BAA6" modified="2018-01-31" version="1">MPNTLDVSSVLEILRPVQDPELQKSLVELNMIRNIKIDGGVVSFTLVLTTPACPLREFIVDDCKRAVKQLPGVETVAVEVTAETPKQKGMVDRQGIEGVKNIIAISSGKGGVGKSTVAVNVAVALAQTGAKVGLLDADIYGPNDPTMLGLADAKVMVKDGKSGESLEPAFNYGVKLVSMAFLIEKDQPVIWRGPMLNGIIRQFLYQVNWGDLDYLIVDMPPGTGDAQLTMAQAVPMAGVVIVTTPQTVSLLDSRKGLKMFQQLGVSVLGIVENMSYFVPPDMPDKQYDIFGSGGGERTAAELGVPLLGRIPLEIPLREGGDSGVPIVVGQPGSASARELRAIAGRIAGKVSVAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUV4</accession>
    <name>A0A2G4EUV4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cobalt transport protein CbiM</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Energy-coupling factor transporter probable substrate-capture protein CbiM</fullName>
            <shortName evidence="11">ECF transporter S component CbiM</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cbiM</name>
        <name evidence="12" type="ORF">CP500_022400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the CbiM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000226">
        <property type="protein sequence ID" value="PHX53268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53268">
        <property type="protein sequence ID" value="PHX53268"/>
        <property type="gene ID" value="CP500_022400"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01462">
        <property type="entry name" value="CbiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018024">
        <property type="entry name" value="CbiM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002751">
        <property type="entry name" value="CbiM/NikMN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43627">
        <property type="entry name" value="PTHR43627"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01891">
        <property type="entry name" value="CbiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00123">
        <property type="entry name" value="cbiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 11" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0170">Cobalt</keyword>
    <keyword evidence="2 11" id="KW-0171">Cobalt transport</keyword>
    <keyword evidence="8 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="252" mass="26786" checksum="AE6E82053EC4F75C" modified="2018-01-31" version="1">MKARNRKLVSLGLMAGLSCYLVLGSATPAAAMHISEGFLPVQWAAFWWIVALPFFVLGLRAIARITKEHPELKLLLALAGAFTFVLSALKIPSVTGSCSHPTGTGLGAILFGPAVMAVLGALVLLFQSVLLAHGGLTTLGANMFSMAIVGPFAAYFIYQLLMRTGSQRVAIFCAAALADLLTYVVTSIQLALAFPAASGGFMASFLKFASIFAITQVPLAISEGLLTVLVWNWLHSYGQPELEILKLLKQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV35</accession>
    <name>A0A2G4EV35_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53399">
        <property type="protein sequence ID" value="PHX53399"/>
        <property type="gene ID" value="CP500_021640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8717" checksum="9A73969914073B6D" modified="2018-01-31" version="1">MTELLQQAIAQIQKLPPDRQDAIAARFLAELQNEQKWETRFADTTDDQWDQMAAMVRQEIAGGETVPLDEVFPTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVA9</accession>
    <name>A0A2G4EVA9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Metal-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000194">
        <property type="protein sequence ID" value="PHX53465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53465">
        <property type="protein sequence ID" value="PHX53465"/>
        <property type="gene ID" value="CP500_021390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003772">
        <property type="entry name" value="YceD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02620">
        <property type="entry name" value="YceD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="171" mass="19522" checksum="6A4B5EAD25CDEC5E" modified="2018-01-31" version="1">METIYIPRILSKSEQTEVIDFDEFIPDLASLTPVRGRLEVTHQGTYLEVKAKAETIVTLTCHRCLKQYNHRLKLNSSELIWLDKTADRPETHPIEMKVDFEDLTETLSPTGSFSPSDWLYEQLCLAEPHKQICDAKCVGIIINDDDTNTESSETISDSRWASLVALKRQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVJ2</accession>
    <name>A0A2G4EVJ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Multidrug ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000179">
        <property type="protein sequence ID" value="PHX53549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53549">
        <property type="protein sequence ID" value="PHX53549"/>
        <property type="gene ID" value="CP500_020905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="262" mass="30673" checksum="09A28E0484726C35" modified="2018-01-31" version="1">MTKSIRIAKTLLITYYAYMLEYRAELFLWALSGALPFILMGVWMQAAQNGEFGLKSIDFARYFLAAFIVRQTNVVWVIWEFEKQVVQGTLSNKLLQPLDPVWHHFSSHVSERFARLPFVFGLVLLFFMLYPQSFWLPSAGRFFLFLLVISFAFCLRFLIQYTFALFAFWIERASAIEQFWFLIYLFVSGLVAPLEVFPASVREVVLWTPFPYLIYFPASILMGLPVDVGRGLLVMFGWSAIFFVWNRWLWRQGLKQYSGMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVM1</accession>
    <name>A0A2G4EVM1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Addiction module component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53579">
        <property type="protein sequence ID" value="PHX53579"/>
        <property type="gene ID" value="CP500_020775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013406">
        <property type="entry name" value="CHP02574_addiction_mod"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09720">
        <property type="entry name" value="Unstab_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8672" checksum="A64A8EEF4D67984E" modified="2018-01-31" version="1">MTLENLEAEILALPKDSQVILLSRLLKHLGQSREIDPEVTTIWSEEAERRDREMDSGEVTGIPAEQVFQKIRGLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVZ7</accession>
    <name>A0A2G4EVZ7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_020020</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53694">
        <property type="protein sequence ID" value="PHX53694"/>
        <property type="gene ID" value="CP500_020020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="10">
        <location>
            <begin position="78"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="9">
        <location>
            <begin position="351"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="639" mass="69549" checksum="8BC3A7224B9DE842" modified="2018-01-31" version="1">MSTNAVRKSTEKSATVFEFVQSVSKVTAGTILSITMLASSVVAGGLVGLAISFRNLPDVRILQTYSPTETTHIYDINGKPLASIHDEANRDVVPLDKISPNLKRAALAIEDSNFFTHKGINPGGIARALIVNLEKGRTVEGGSTMTMQLVKNLFLSPKSKLSRKVAEAVMSIRLEQILNKDQILQLYLNQIYLGHNLYGVETASRSYFNKSADNLSLAEAAMLAGLISAPEEYSPFVNYKLSKDRQEIVLTRMKELKWITPTEEAAARKQKIKLGKITSFGGSQVPYVTQAVVQELTRRFGRDAVVKGGMRVQTTIDLKMQRTAEETVKAWHDRLYGQGIFYDRDQGQIALAAVDPRTHFVKAMVGGVDYEKSQFNRAIQARRQPGSSFKPFIYYAAFASGKYGPDSVVYDSPVGYRDGDGYYYPQNYGGGFSGAVTIRRALEVSLNIPAIKLGQEVGLNKVIEICRVLGIRSPMEPVVSLPLGAVDLTPLEMAGAFATFANNGWHSDTTFIVQVTDSSGNVLLDNTPKPKLVLNAWAAASVNSALQGVVNSGTARAAQLGRPAAGKTGTTSSERDIWFVGYVPQLSVAVWVGNDDYTPMSYGATGGTLVAPIWRDFMSQALQGVPAEDFKPASAFERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW93</accession>
    <name>A0A2G4EW93_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000158">
        <property type="protein sequence ID" value="PHX53738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53738">
        <property type="protein sequence ID" value="PHX53738"/>
        <property type="gene ID" value="CP500_019835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="546" mass="57195" checksum="6FAD9D093E571E11" modified="2018-01-31" version="1">MNDSYSLANALSEPLRQPFWWAALASVGLHGVLGVNAPKISNLIYGGNSSKNLPGSVGLVELTPTEMGRLPQTIPSLKSNGKSPLSIAPVPLPPKLTPPLPPAPTAINLPALPPGMPPPGFFSPLPPSPLPSLTPPTPPTASTPTAAVKGPTVKIPLAIPPQPPANQLFPPPVNFDPIIPPPPPSSPAPELPRFLPGESEETNPDVLRRMIERSAVPGLTSATDIATPKDFQPGGRYSSEPDRDQQNTTPKTPEEIAREAIFDRNNQDLQRRNLSPDREAMLDAGDKYITLFEKFKKAYSDLAMTGPTPVNIPYPKAACSQKLEGKAVFGALVNTQGLVKAEPQAIALTGSSILDDAAQAMINSSLILPAASTHKLYQLTFEFKYDEKVCSGIPVKASPAPTGPQPTLPQLTLPSPVPPVPSPVVQPSRSPAPTAQPKPRTQQSPLPQPKPGTQQSPLPQPKPGTQQSPLPQPKPGARDLILPQPQPAAEESPAPEPQPAPEESPTPQPTASPTTESSPSPSPTASPVAAPSPTTEPSPTASPSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWA1</accession>
    <name>A0A2G4EWA1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53748">
        <property type="protein sequence ID" value="PHX53748"/>
        <property type="gene ID" value="CP500_019740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="87" mass="9566" checksum="E5A5959051ECFB05" modified="2018-01-31" version="1">MRPEAGIISNRRRISGSGFIYILGNWELGIGNWGIGNGEWGIGNWELGNWGIGELGIGDYIGIKQSYPSRLRRGGFINNNCLKPTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWD9</accession>
    <name>A0A2G4EWD9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Replicative DNA helicase</fullName>
            <ecNumber evidence="4 15">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">dnaB</name>
        <name evidence="20" type="ORF">CP500_019555</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 15">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4 15"/>
    <dbReference type="EMBL" id="NXIB02000154">
        <property type="protein sequence ID" value="PHX53788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53788">
        <property type="protein sequence ID" value="PHX53788"/>
        <property type="gene ID" value="CP500_019555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003586">
        <property type="entry name" value="Hint_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006142">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004042">
        <property type="entry name" value="Intein_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14528">
        <property type="entry name" value="LAGLIDADG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00379">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00305">
        <property type="entry name" value="HintC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="SSF55608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50819">
        <property type="entry name" value="INTEIN_ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="6 15" id="KW-0235">DNA replication</keyword>
    <keyword evidence="14 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 15 20" id="KW-0347">Helicase</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-0651">Protein splicing</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DOD-type homing endonuclease" evidence="17">
        <location>
            <begin position="322"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="18">
        <location>
            <begin position="394"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="INTEIN_C_TER" evidence="16">
        <location>
            <begin position="684"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="SF4 helicase" evidence="19">
        <location>
            <begin position="706"/>
            <end position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="PHX53788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="935" mass="104930" checksum="066F4E7133C42B10" modified="2018-01-31" version="1">MSDLMPTNVEAEEAILGGILIDPEAISRIAELLRPEFFAISAHQVIYRSALDLFFQGQPTDLMTVTTRLADRNQLEQIGGQTKLAQLVDRTVSAVNIDQYAVLVEDKYQRRKLIEAGNNIVQLGYETATPLETVLDRAEQQIFGITQDRPQQDLVSIGETLNQTFQDLENRNEGLTLPGIQCGFYDLDAMTGGFQRSDLIIVAGRPAMGKCQASSTIALEGDGSLSTIQQIYQKRQAELLTLGKDWKFHLTRPSDFIDDGIKPVFRVTTRLGRFIETTITHPFLTIKGWRQLEEIQVGDKIAVPRKMNVFGKETIRDCEVKLLAYLIGDGCLTQDAPRFTNGNTAILQDFAEAAISFGGLRLRFNDKGRRAPEYRIIGDREDYTKKIDLFGWNLHKLLEERDLYIQEFAQKLGVSPILVSSWVQGIAFPNQALFTRTCEILEVDPKQLAGPGMDAVHTTHKNPLRFWLEELGLMGKGAHHKTVPDIVFKLERSQVALFLNRLFSTDGWATLLTSGQSQLGYCSVSEGLARHVQHLLLRFGIIAALKKRFVKYKNTRRPAWYIDISDAKSIKTFISEIGIFGKEAALSKVEEALENKISHNNRDLIPVEVWEYLALAKGNEPWASLAKRAGIKGYSNIHVGQRALSRERLLVLANALDNSSLKQLANSEVYWDEIVSIEPMGNKQVYDLTIPETHNFVANDICVHNTAFCTNIAHHIAAGPQKLPVAIFSLEMSKEQLVQRILSGEARIESNRLRSGRISQNEWEPISAAIGRLSELPLFIDDTPNITVTEIRSKARRLQAEQGGTLGLILLDYLQLMEGSSDNRVQELSRITRSLKGLARELAVPIIALSQLSRGVEARTNKRPMMSDLRESGSIEQDADLVIMLYRDEYYNPDTPDRGIAEVIITKHRNGPTGIIKLLFDGQVTKFLNLQARRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWE4</accession>
    <name>A0A2G4EWE4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000155">
        <property type="protein sequence ID" value="PHX53786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53786">
        <property type="protein sequence ID" value="PHX53786"/>
        <property type="gene ID" value="CP500_019625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="452" mass="47063" checksum="A3C0E3746195C5EA" modified="2018-01-31" version="1">MPSSPAVYENLAKRLVYIDDNPQLQAVVQGGLTAAGYRVDRTFNDPATGFHAIGLISTTPDKPPVLVFRGGDEAIDDVANADPRGTGFNQFEANKQALGNWLTQISQDTTKNPNRLPPDVLGHSLGGAIAQLAATEFTSAIGDIVTFNSPGVDQDTVNIFKQKVGAGKNVTHYIVSGDFVSLGGEAFLPGKVFFQTFVDPIINPLLVLQKHTTSGLLTTPPPGLIQTEISVDQLNRPDFTFADSDYLELLAGLDSALPPLKAALQSRATLEQLRVTPGTSFFGNIIAMQTALDPSKPNNLVGDSANNIAFGLAGDDTIIGNAGNDTLSGNRNNDTLSGGLGNDLLFGGKGDDSLNGGEGNDTLIGGLGADSLIGGAGRDVFVLGTGAGNDTISEFQKGEDLIGLTTGLTFSQLRINPTQNAIAIQLASTGEVLATIPGIQTIALTATDFISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWQ3</accession>
    <name>A0A2G4EWQ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53896">
        <property type="protein sequence ID" value="PHX53896"/>
        <property type="gene ID" value="CP500_018955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="730" mass="82353" checksum="D98BD4D6AB3E94A2" modified="2018-01-31" version="1">MSSDSIWIVGAARSGKTTRLIEQFCIWSKTVKPLPARVSSRLVSGRGRIGQTGPTILVLAANGENRLELTDRLTCATQGKYTFNSTTPFGFFEQEVMLFWPLLVESLDLRAQFPIRLQPEKELELATRLWRREIDEGILQQIGVNPNRMVRRTLDLLQLAAVSGTPIEQIPSILEQGFAQEGGSSHLWTSMGNLLERWREWCLRRGFLTYGIICELYWRYLLQNQTYQQHLADRYQAVIADDIDDYPAISSHLFEFLLLRGATGAFTYNPDGGVRLGLGADTAYMARLETRCVRVENLDRQAGLVADVGELAVNLTVDSDNFYPFGLSLPESVRSIQTTSRAQLLRETAEIIADAVKSKAVGPGDIAVIAPGIDAIARYTLTEILARDNIATESLNDQRPLSSTPAIRALLTLLALVYPGLGRLVDRDAFAEMLVVLGSQRNRQGEEEWEPEANNQKSQIPNLKSIDPVRAGLIADHCFCPDLDRPQLLPITAFSRWDRLGHRAAVAYEQIVEWIEEQRAQQQERLLPSPLSLLDRAIQKFLIFDRYLAYDRLAALRELMETATHYWEVDGRMQQIEPKAGSDSETIAGFIQLLRQGTVTANPFPVRPDGLDSQTVTLANIFQYRSSRRAHKWHFWLDAGSSLWLEGGAATLYGAPLFWRSQLGRSWQTEDEEAEGEKRLRRILVDLLSRCSQLYLCHSELAVNGQEQTGPLMPLIHNSVSYQRRSIGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWT0</accession>
    <name>A0A2G4EWT0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53981">
        <property type="protein sequence ID" value="PHX53981"/>
        <property type="gene ID" value="CP500_018575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="122"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="668"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="699" mass="78737" checksum="6991E1F6EDD1034D" modified="2018-01-31" version="1">MSPKFEKLLQRIQNVQNFVATRVNQNPTFGTVAQELNKLADTLKVGKLRIQIVSESPVLAESLQNLVSTRKNLAAIYQFKTVPLPSQSQRTEIASPAAVILKYANSAGEQSTRFSLSKNQKVVIGRSADCQIRIPDECKFVSGHHAEIVPLVNSGFGKTDWQFCDTSSNGSYIKGQKLLKGCRTLQTGDVIILGYPEATRSSPEIVVDFQFNPAAENVNNQIEKQLIDCDILYLVVSSGQTLSADEKQFIDRAIKAQVLKVVIAVDSTATSQESQANLAAVDTWIKSQNFSQSLVLVSAPISSFYPNSQANRVELSAQLESNLLSQVLENIANGEFEEVLKERVKKQFLAQINILDSLFKKQEDTLKQESQKLEQLLRELSDQEINKVFQQVNADKDKTFQQIKSKILESKDAFIHPFTKKSLLHRIKLFTEELKPVMTKKGSEVYLSLTSDHLGERESLNIYMTNNLCYKEIINWVNEEWKRICYNYADGGLNGLFHRTETKLFKLTQNQNLPNSSFYSDQPNFDVYKYLKDSLVEFPSEISYQEGGSPIGGVVGMAVSALIGYVGFAGVGLPPGTPGNPLALIQAFNNIINILIRGDERQQQAAGRLKQQTENLKKGLCNHYQGLAKFLVEKMGQNCFFLSLFDTEARRLREMTESIKNERINPYINEIKKRLEQCNNQQNALKKQQMELMQRIKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX09</accession>
    <name>A0A2G4EX09_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_017970</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54085">
        <property type="protein sequence ID" value="PHX54085"/>
        <property type="gene ID" value="CP500_017970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="12"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="533"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="494"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="807" mass="90801" checksum="D66CC8A1E707EA29" modified="2018-01-31" version="1">MDNQTYHSVKGNILIVDDISTNLQLLAQILSEQGYKTRTAPNGQLALRSIDLTPPDLILLDIMMPIMNGYEVCQALKTSPKTKDIPVIFISALHEVFDKVKAFEVGGVDYITKPFHEQEVLARVSNQLIQRRLFQQVQEQNKSLESEIIERKNAQEETQFLLATTFALAKSQDFEESISIMLRFCCEFINWDLAEAWIPSIDEKKLTCSRSFYTNEPSFLDYRSQSLEIKFAPNIGLPGRIWSSKQSEWLQDISLEPEQVFLRNKIATKAGLKASFGVPVLLDEQVVAILIFFNKTPMPSQLRLMELIDALATQLGSILQRQLAEEKLKKQFQKEQLLNQLTQSIRSSLKLNTIFSTAVREIAISLGVDRVAIAQYFPEKKLWTNISEYYDATQLETTLGIEFSDNNEISDRLKQSEIVKIDDTNTCGNEIKQRLSQLSPGSWLFVPLKVDSKVWGSVCVVKENRSHYWQVFEVELLCAVADSVAIAIKQAQIYQEIQSYAQQLEDTLTELKNAQAQLVQKAKMASLGQLVAGVAHEINNPVNFIYGNIAVAMEYGRDLLHLVALYQNNYPQPVAEVRQKLDNIELDFIADDYPKLLNSMKDGASRISQIVLSLRNFSRLDEKEYKSVDIHEGIDNTLLLLQHRLNGSNNGKEIEVIRDYTQLPKIQCYASQLNQVFMNLIANAIDALETKSSPRQITITTKRDISESPLAISGSIVILVADNGCGMSEKVCDQIFDPFFTTKPVGSGTGLGLAICHNIVVEKHRGQISCVSGLGEGTEFMVQIPIDLSTSIGNKLEGSRFCQYLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX14</accession>
    <name>A0A2G4EX14_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LPS export ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lptB</name>
        <name evidence="5" type="ORF">CP500_018020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54092">
        <property type="protein sequence ID" value="PHX54092"/>
        <property type="gene ID" value="CP500_018020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03218">
        <property type="entry name" value="ABC_YhbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030921">
        <property type="entry name" value="LPS_export_LptB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04406">
        <property type="entry name" value="LPS_export_lptB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="242" mass="27341" checksum="6B7CFA437F62F011" modified="2018-01-31" version="1">MKIVLENIHKSYGKRNIVSRVNLSVAQGEIVGLLGPNGAGKTTTFYIATGLEKPNQGTVWLNDLDITQLPMHKRAHLGIGYLAQEASIFRNMTVRDNILLVLEQTQVPRWEWRERVDFLLQEFRLEKVASSLGIQISGGERRRTELARALAAGRDGPIFLFLDEPFAGVDPIAVNEIQSIIAKLRDRKIGILITDHNVRETLEITDRAYIMRDGQILASGAEEELYSNPLVRQYYLGDNFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXD0</accession>
    <name>A0A2G4EXD0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prevent-host-death protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53807">
        <property type="protein sequence ID" value="PHX53807"/>
        <property type="gene ID" value="CP500_019520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="87" mass="9657" checksum="2652329522D5EB06" modified="2018-01-31" version="1">MSKRLTIAQAQQQLPNLPQELTDEPIVITQDGVPVMAAISYNYLTELLETLDILTDIEFVTKLRQSITQAGEGKTISWENAKAKLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXE2</accession>
    <name>A0A2G4EXE2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">CP500_017635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54148">
        <property type="protein sequence ID" value="PHX54148"/>
        <property type="gene ID" value="CP500_017635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="10904" checksum="E11B3E81ED730DFF" modified="2018-01-31" version="1">MAAVSLSVSTVKPLGERVFVKVSASEEKTAGGILLPDTAKEKPQVGEVAAVGPGKRNDDGQRVEMEVKVGDKVLYSKYAGTDIKLGTDEYVLLAEKDILAIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXG8</accession>
    <name>A0A2G4EXG8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein insertion efficiency factor YidD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54234">
        <property type="protein sequence ID" value="PHX54234"/>
        <property type="gene ID" value="CP500_017345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002696">
        <property type="entry name" value="Membr_insert_effic_factor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01809">
        <property type="entry name" value="YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01234">
        <property type="entry name" value="Haemolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="220" mass="22184" checksum="DD8ADBA3361D2EB0" modified="2018-01-31" version="1">MQTPIFDAALRQLAVASISGYQKHISPIKGFSCAHRVLYGGESCSQYIKGAIAKLGLFGAIKASRHRFAACKGANQILKARFSSESGSESGSEDSNFEGNDEPKSDRPKSQGGTPRRSSQGENYCIEGLDCGSADCSGLDCSSADCSGLDCSSADCSGLDCSSADCSGLDCSSADCSGLDCSSADCSGLDCSSADCSGLDCGSAGCSGLDCGSAGCGSCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXJ3</accession>
    <name>A0A2G4EXJ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54198">
        <property type="protein sequence ID" value="PHX54198"/>
        <property type="gene ID" value="CP500_017455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="153" mass="17734" checksum="8C8A4FFACDA69F4F" modified="2018-01-31" version="1">MSANISYSPDLDRVPEIFTRHLGTWKGEYIKTDTRGHFTRSFFGNFTISIEGSHYRQVNNYEYSDGSRLQLNFEGEFENRILKLYSSSYSDFSAIAWDAGQEVICFRATKTQDNAVITFMETMTLLSENHRVRSTQAFKDGVFDGISFIEEMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXM5</accession>
    <name>A0A2G4EXM5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54271">
        <property type="protein sequence ID" value="PHX54271"/>
        <property type="gene ID" value="CP500_017010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="153"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="370" mass="42372" checksum="DC1D439BF239F489" modified="2018-01-31" version="1">MNRIKFIGNAVGTIIAAGTTAYLLSDKSNLSRADLKPSGDRNQTLKPDEKEILFLASLAPSGHNTQPWFVQYLAPYHWIIGNDRTKWLPAVDPTQRETMLSIGTFIQNLEYAAGAFGYLCDWNLLAKTNQDDRVMEVKLIKQTSNNPFDTAKIKNRRTVRSDFLSDVLKKEDLKYLVNSEPEFIHYLPNTSKESQFIDEQTIVANRLQAYRNPAQQELADWIRFSSKNADKYRDGLTTGSMEIEGISGWVVRNFYNKDNVMKNDFREVGIDKVKKQVSESAGWILITSKDSVAALLETGRRMQRLFLKVREKGIAIHPMTQILEESSTRQQLNQSIAIGENIQFILRVGYLKNYPPSVSLRRPVDWFLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXQ8</accession>
    <name>A0A2G4EXQ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1036 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54309">
        <property type="protein sequence ID" value="PHX54309"/>
        <property type="gene ID" value="CP500_016880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009380">
        <property type="entry name" value="DUF1036"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06282">
        <property type="entry name" value="DUF1036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="311"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="498"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="677" mass="75726" checksum="C5B71427E68B2982" modified="2018-01-31" version="1">MTTTHVLYPTITKYYSAIRHPQVAFKNTDPLLAAGKPVEISNSQGIRNLWSAAGGFACVFKYETFTPQKLWAVRCFLQSTSSVATHYSKVSSRLPNIPCSSYFVECSFLAQGIRVDGNLYPTVKMEWAEGKDLRTFIRDNLNNKNKLDLLAQAWVKLSKDLADNGIAHGDLQHGNITVDDSNGVNLKLIDYDSLYFSVDGNGINDEIKGIPDYQHPLRSQLQKQCLEIDFFPQLVIYLSIVSIAENPQLWSNYNLDNTERLLFSVPDFQNPDRAQVFQVLSQLSPNIARLADELKKICKLTDFSKIPSLDTVLTPPVTKWNPAGSGTTSTTQNPQTQQWNPSGGTATNQPQNPQPQTWNPVGSGTTSQPQNPQTQQWNPSGGTATNQSKNPQPQTWNPTGSNSTNPNINTSQTSLTQQTQKGSYPVVVKTIAVISTVIATSLGGFCYYQYQQINQVKQQIEKIRLDKKILPPKGNKPSLSVELQNMMNVVQGKESFLYQDIEQLVSRIESQKSDFEKDINNWQSRVNKLEGEKGSLQEERDQLQSKVNEYEKYTYVNFCNKTPSKTIAAAFAYWDGKGLTSRGWWIVEPGKCTEIVVEQNYRGNVYIHGTYNRGERSWGSGDSSFCVDIVNVFKMPNSDKASCSGGNLKQVTMSEFAVSPGTNNWDFNDKDSTGTDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXU6</accession>
    <name>A0A2G4EXU6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54306">
        <property type="protein sequence ID" value="PHX54306"/>
        <property type="gene ID" value="CP500_016865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="13764" checksum="5481E7BA5EC59557" modified="2018-01-31" version="1">MSGIDRELTLETRTSLIDKHLPGTQKAESELESEGIVHLFNDRETMERVVTEIKLRGERTGSDDLEDNYERYGLYFSEPIGYILKADGTRIPLQYGEIKIKKTTGKYHVIPRTRPRTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXW1</accession>
    <name>A0A2G4EXW1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54372">
        <property type="protein sequence ID" value="PHX54372"/>
        <property type="gene ID" value="CP500_016500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9426" checksum="9B77FCCA4660F543" modified="2018-01-31" version="1">MLKQMCWLPRYGSNGETILHLRTEPRQSWRPYTAFPQYAASDYLEPDGSKGWATFQKLRAQGWNLISTQEGLQSGFGEQRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY57</accession>
    <name>A0A2G4EY57_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000104">
        <property type="protein sequence ID" value="PHX54390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54390">
        <property type="protein sequence ID" value="PHX54390"/>
        <property type="gene ID" value="CP500_016400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="17476" checksum="F889F3A4A9525642" modified="2018-01-31" version="1">MFNTILTQQRQVLGTFSSREDAGKALDCLVFAGFPLAQVFLLGQGSQERQNSLNLPSDSFGAIAGTATGLKKGMFLGNLLGGATGLMLGVGLLALPGVGQVLLSGAIGFTLLSGGICTAAGGLMGALIGLGLTSEQAKAYQRQISQGSVLLIVEGSGQEVDRAKYLLAQSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY58</accession>
    <name>A0A2G4EY58_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54462">
        <property type="protein sequence ID" value="PHX54462"/>
        <property type="gene ID" value="CP500_016020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="13026" checksum="F1E0FE655327EF26" modified="2018-01-31" version="1">MDKTLVNLTLAVVTEEVENILDAYPRYPYQEAFSPSGLRQDLIAYVLSRIPNTYAAIAPSDPLSNNSVQIRCSSEQLLHIENLIHTGISDVLHNYDKIDYHIPESFNFGATVANLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY85</accession>
    <name>A0A2G4EY85_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphoglucosamine mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_015820</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000097">
        <property type="protein sequence ID" value="PHX54481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54481">
        <property type="protein sequence ID" value="PHX54481"/>
        <property type="gene ID" value="CP500_015820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="6">
        <location>
            <begin position="9"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="7">
        <location>
            <begin position="163"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="8">
        <location>
            <begin position="268"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="5">
        <location>
            <begin position="409"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="476" mass="51840" checksum="FBFF7C252D4B5173" modified="2018-01-31" version="1">MSSSNSTEIKFGTDGWRGLIAHDFTFANVRKVTRAIASYLETAYTKDRPVLVSYDTRFLADEFARTSAEVLADLGWTVMVVDRDCPTPVIAYSAKHLNSAGALMFTASHNPAPYCGIKYIPDYAGPATPEITDTIVANITGASDAPAIGSHNDKISTFDPKPEYLKFLYTLIDVDRIRSAKLKVKYDALYSTSRGYLDEVLQHCGCDLESFHTYRDVLFGGGMPEPKGEQLVELVEAVKKDSADLGLATDGDSDRFGIVDELGNVLTPNTVLLLLARHLVKNKGLTGAIVRTVATTHLLDNMAAKYGLKIYETAVGFKYIGEKMRETAVLIGGEESGGLSVLGHIPEKDGILADMLVAEAIAYEGKPLSQLVEEAIREADGPLYNQRLDLHLDDAHKAAVLASFTNNPPSEVAGIGVKEIGRKDGIKLYLEDGGWILLRPSGTEPLMRVYMETNSVEKEAKIAAHMKQVISHLEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY90</accession>
    <name>A0A2G4EY90_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hemolytic protein HlpA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000097">
        <property type="protein sequence ID" value="PHX54489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54489">
        <property type="protein sequence ID" value="PHX54489"/>
        <property type="gene ID" value="CP500_015860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="36587" checksum="E9FBAE8B5A24525D" modified="2018-01-31" version="1">MPHSHIKTPIIFVIFNRVDTTEKVFEAIREVQPPKLLVIADGPRANKPGEAEKCAAVRAIIDRVDWDCEVMKNYSEINLGCKDRISSGFNWAFDNVEEAIILEDDCLPHPTFFPFCEQLLEHYRDDKRIMSIAGVNLQFGRKRTEDSYYFSRFSNCWGWATWRRAWQYYDVDMKLWPQLRGSGFLENLLANPQSVKVWDSAFQVSYDGTVNNWFFRWLFTCWVQNGLAIIPEKNLISNIGFGSQATHTSAEDSIYSNMPTQAMTFSLRHPNHAIRHFVADQFTQDTFYDYHPALIRRIKKKINKLCGSTIFNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYA6</accession>
    <name>A0A2G4EYA6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54512">
        <property type="protein sequence ID" value="PHX54512"/>
        <property type="gene ID" value="CP500_015715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="159" mass="18127" checksum="3ADFC4A0E63FFF1C" modified="2018-01-31" version="1">MRIKSLSIKPVSRLSIICAIAIALVISSPNLAKAESREQAVDRLTDFLFYKVNPQLNNRKLQAGDRNYITEWQKLRTAIDPRVKSAQEVCYSPGPGETGWEFTTINGQTYQQTYDRLADIIFYSRHPQTAEQQIPIGDEASSKEWLAIRREMYISNCGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYI1</accession>
    <name>A0A2G4EYI1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase III subunit gamma/tau</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dnaX</name>
        <name evidence="7" type="ORF">CP500_015755</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DnaX/STICHEL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54520">
        <property type="protein sequence ID" value="PHX54520"/>
        <property type="gene ID" value="CP500_015755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18137">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022754">
        <property type="entry name" value="DNA_pol_III_gamma-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012763">
        <property type="entry name" value="DNA_pol_III_sug/sutau_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045085">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12169">
        <property type="entry name" value="DNA_pol3_gamma3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02397">
        <property type="entry name" value="dnaX_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="37"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="372"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="531"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="419"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="531"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="587"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="685" mass="75817" checksum="5F99D8E7EBF51545" modified="2018-01-31" version="1">MTYEPLHHKYRPQTFAELVGQEAIAQTLTSAILQDRIAPAYLFTGPRGTGKTSSARIFAKSLNCISTGAPTPTPCGKCNVCQEIARGSTLDVIEIDAASNTGVDNIRDLIERAQFSPVQCRYKVYVIDEVHMLSTQAFNALLKTLEEPPDRVVFVLATTDPQRVLPTIISRCQRFDFRRIALDSMTAHLHKIAKLENINIASDAVYMVAQLAQGGLRDAESLLDQLSLFPDEITVEKVWDLVGAVPENDLMELLEAIKKDDPTALVDMTRHLMNRGREPLIVLQNLASFYRDLLIAKAAPKRSDLVALTSATWDKLVKFATQWDAELILASQKHLQTHEVQIKNTTQPRLWLEVTLLGLLPSAIRTQQQQIYPPQPPLAKGGSQTPPQPSQSAGSQTSNIQQSSVPNSQNPPPQSPPIANRTEITSTAPIPASVPTAETNQTNYTPTNSADEIDLNRIWEQVVVHVRPPGTQSLLRQHGHLVSFSNDAAVVRINSQPLLNMVKDKVANIEEAFLQIFNRRIVVKLGMTNPQETNSLRSQDLPISNRRIGENSRNPNPVGDANPPEENSPFADIPNDFLRNREEVQKSPSAPENTSVKPSNISEPRRETNGSIASGNDLNTQAVAVRTDAQDVVHSAGVWAEMFDGEVVDFSDGLEVWESEIFRLEPESDLTQLSSESDEDDFIDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYN5</accession>
    <name>A0A2G4EYN5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_015010</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54632">
        <property type="protein sequence ID" value="PHX54632"/>
        <property type="gene ID" value="CP500_015010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="13">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="11">
        <location>
            <begin position="169"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="12">
        <location>
            <begin position="295"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX54632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="420" mass="47882" checksum="712900C09E5B22F7" modified="2018-01-31" version="1">MLISFKTALVLNNKQVTAFRQHCGVARHAYNWGNAVIREILELRETDKSIKVPSSIDLHKRLVAEVKPENPWYYQVSKASPQQALAELRTAWDRCFKKVSKQPRFKKKGRSHDSFYLEQGTKAKPGIRNDGKRVKLPKIGWVRLTEALPVTSIHNCVISRTGDRWFIAIKYEIEKPVVVANRPTVGVDIGIKELAVTSDGKVFSNPKAYRRMSKKMKRLQRSVSRKVKGSKNRWSAIRLLARHHAAVANIRKDAIHKLTNHLAKNHSVVKIEDLSVKAFLKNHKLAGAIADCGMYEFKRQLEYKTEKFSSQLILVDRFFPSSQICSGCHVHRHKMPLKNRVYHCPECGHTEDRDLNAAKNIERWFEGIHIPIRSDQTVSSTEIACGADKPLKSHLETALKQEVSIETTKVQLSRDLGSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYN6</accession>
    <name>A0A2G4EYN6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54588">
        <property type="protein sequence ID" value="PHX54588"/>
        <property type="gene ID" value="CP500_015225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="454" mass="50659" checksum="A2C04B2E77FE6B4A" modified="2018-01-31" version="1">MTTRVILVRHGQSTYNLERRIQGRLDKSILTEAGRAAALQVGETLSSITFDAAYSSPLQRAKETAEIIVSRLTNPPQLQPTDQLMEIDLPLWEGMLRQDAIDQFPEAYHCWQQNPDKFSMKLPSNEAEIEHFPVLAIFANARTFWKELLSKHSSGTILVVAHNGINRALIATASEVSPAYYQSIQQSNCGISIINFGTSAVAKDEQNEQNKKVAVQLESLNLTAHTGEIFPKPRDGNRGPRLLLVRHGETDWNRAGKFQGQIDVPLNDNGREQSRKAAEFLKNIKLDFAISSSMLRPKETAEIILQYHPDLQLELRDELREISHGLWEGKFESEIESSYPGLLAEWKTSPETVQMPEGENLQEVWQRAIASWRDIVQSVSGTGIVVAHDAINKAILCHLFGLEPEHFWKFKQGNGAVSVIDYPHGPEGLPVLQAMNVTTHLSGSVFDQTAAGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYP9</accession>
    <name>A0A2G4EYP9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismate synthase</fullName>
            <ecNumber evidence="3">5.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_014935</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate = isochorismate</text>
            <dbReference type="Rhea" id="RHEA:18985"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="EC" id="5.4.4.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the isochorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.4.2" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54651">
        <property type="protein sequence ID" value="PHX54651"/>
        <property type="gene ID" value="CP500_014935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008909">
        <property type="term" value="F:isochorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004561">
        <property type="entry name" value="IsoChor_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00543">
        <property type="entry name" value="isochor_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="5">
        <location>
            <begin position="214"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="477" mass="53208" checksum="9EE5D53AA00B5E21" modified="2018-01-31" version="1">MTVIPHRANLLQNRNQLHQLLLDCQQSLTDKYQTKIVSISQEIYPLDPLAVLQEISEPCQRHFYFEKRDPIPDKSFAIAALDSAIHLTVAGSDRFAAAQNFIRSTLASTITIGAERLPFSGPHFFCSFAFFDDNIYDNSYFPPATIFLPKWQITRQQDSCILVANALVEKNINVKNIAENIWQTFDKIASRKYPKLTNYINNSIFFKQIPVNDANRFKTSVKSALELIESKYFSKIVLSQAINVLSQTSFSVIDSLNNLRLSYPGCYVFSTTNGKGQNFIGASPERLISIHNNQLSTDALAGSAPRGKTEAEDANLARGLLQSEKDIREHQVVIDFIVDRLYKLGMIPNYSAIPRLLQLSNIQHLWTPITAQIPTDIHLLNILAQLHPTPAVAGVPRDIALEQIRRCESCDRSLYAAPIGWIDARGNGEFAVGIRSALIDGDRAILYAGAGIVAGSEPEKELAEIQLKLQPLLNALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYS0</accession>
    <name>A0A2G4EYS0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54636">
        <property type="protein sequence ID" value="PHX54636"/>
        <property type="gene ID" value="CP500_015045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="165" mass="19624" checksum="3A8E3E39AB713369" modified="2018-01-31" version="1">MPKYLVGVSYNPDAETENIVRAKRAIRPYAPTAEEFKCRTAYFDYAVPEHFDVVYPERSRRAQHKRSRWAVTNRHPMAFSTTEFFGKIMSFELTITFGLATQNSHFFFKQLEMHLKPDIYNYLYPLADVDRDFNNLPLFQNTSNLKHIKLSKEQFHPHKCHKLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYS6</accession>
    <name>A0A2G4EYS6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014805</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54685">
        <property type="protein sequence ID" value="PHX54685"/>
        <property type="gene ID" value="CP500_014805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="11"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="138"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="138"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="27798" checksum="90092FCFEE8D96ED" modified="2018-01-31" version="1">MLHNLENHKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEALEIFRNTEPDLVVLDVMMPKLDGYGVCQELRKESDVPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVDKNGSSGIPSSGVIQVTNIRIDTNKRQVYKGDERIRLTGMEFSLLELLVSRSGEPFSRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIVEPGELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYV6</accession>
    <name>A0A2G4EYV6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54694">
        <property type="protein sequence ID" value="PHX54694"/>
        <property type="gene ID" value="CP500_014640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010349">
        <property type="entry name" value="Asparaginase_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42110">
        <property type="entry name" value="PTHR42110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06089">
        <property type="entry name" value="Asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="317" mass="34915" checksum="B14E9C57FEBB3E8D" modified="2018-01-31" version="1">MTRGKRTQAPELEVRLLREGIVESKHRVQATVCDNRGRVLSVAGNSETATFVRSSLKPFQALAVTASGTLERYELTDRDLAIMCSSHQGTIEQSRQVFNVLWRCDIDPSRLQCPIPEGKKSSLQYNCSGKHAGMLAVCQQLHWPLETYLRRKHPVQQLILGKVAELLAMPAEEFISARDDCGAPTYLLQLGQMASLYAKLASGDNVDMERIVRAMTHHPTMISGEGRFDTELMRLTQGEVVSKSGAEGVQCIGLVGEGMGLAIKVTDGAKRAQYAVAIHLLKQLGWITAAIAETLSETYLTLSEFKRLEVVGEVSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYY3</accession>
    <name>A0A2G4EYY3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2127 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54722">
        <property type="protein sequence ID" value="PHX54722"/>
        <property type="gene ID" value="CP500_014520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021125">
        <property type="entry name" value="DUF2127"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09900">
        <property type="entry name" value="DUF2127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="149" mass="16602" checksum="E4240A4E04B45CA8" modified="2018-01-31" version="1">MKKQRPPGLIAIIIYKAFVASLWTLTSIALIFAMKNHQFLEDFSDSYSLDSKVKIIEFLLAKILVLKPKTLLFSGLAAGLYAVLTAVEAIGLWYEKGWATILVLVLVGISIPAEIFELIRGVTVLKLVLFIVNVAVLWYLAHHLPKHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYY4</accession>
    <name>A0A2G4EYY4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54696">
        <property type="protein sequence ID" value="PHX54696"/>
        <property type="gene ID" value="CP500_014650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="17"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="222"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="279" mass="32660" checksum="5797872999E7494E" modified="2018-01-31" version="1">MTIAKSFELEVTHLPDHTELPESDGTFVKNFQELPQSIILTDSLRPILQQIHPDARYRIGQDCGIYWRLTEPLERGAEAPDWFYVPNVPPLLNGEVRRSYVLWKEYVAPLIVLEFVSGNGSEERDRTPPPELGQPEAQKVGKFWVYEQAIRVPFYGIYEVKKAAVEMYHLQDNRYQLMSANERGHYPIPQLGVELGIWQGEYDEMNLPWLRWWDSEGNLLLIGEERAEKERLRAERERLRAGEEHLRAEEEHLRAEEEKQRADRLAAKLREMGINPDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZA4</accession>
    <name>A0A2G4EZA4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tatA</name>
        <name evidence="8" type="ORF">CP500_015740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Forms a complex with TatC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TatA/E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54517">
        <property type="protein sequence ID" value="PHX54517"/>
        <property type="gene ID" value="CP500_015740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7194" checksum="9574557C460AA49C" modified="2018-01-31" version="1">MFGLGLPEMGIIAVVAILIFGPKKIPELGNALGKTLRSFKDGVGLVDDEAVEKEKQKDQDQEVKPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZH7</accession>
    <name>A0A2G4EZH7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1049 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54915">
        <property type="protein sequence ID" value="PHX54915"/>
        <property type="gene ID" value="CP500_013590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="85" mass="9013" checksum="9D6A3F86C9001359" modified="2018-01-31" version="1">MKTIPLLAISSVLAILVSAIAIISVQNATLVSLNFTLFQSIQMPVGIVLALSLSTGFIGGAILLPLWTVSASKPVTDREELEEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZI0</accession>
    <name>A0A2G4EZI0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NAD(P)H-quinone oxidoreductase subunit D4</fullName>
            <ecNumber evidence="9">1.6.5.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_013455</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.3" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54920">
        <property type="protein sequence ID" value="PHX54920"/>
        <property type="gene ID" value="CP500_013455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="3" id="KW-0874">Quinone</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="8">
        <location>
            <begin position="126"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="504" mass="53720" checksum="DC4FA8B5EA3244F1" modified="2018-01-31" version="1">MLSALIWIPILGAAVIGFWPGSVSSKIVRNTAIAIAAITFILSVILATQFDANLSQLQFSEFLPWIDTLGLNYNLGVDGLSLPLVILNCLLTGVAIYSTDESIPRPRLYYSLILLITGGVAGAFLAQNLLLFFLFFEVELIPLYLLIAIWGGERRGYAATKFLIYTAFAGIVLLAAFLGTVWLSGASSFDIVGAIGASHLQGGSPLPLVRQIVLLAGVLLAFGIKIPLVPFHTWLPDAHVEASTPVSVLLAGVLLKLGTYGMLRFGLGLFPDAWALAAPWLASWAVVSVLYGASCAIAQKDMKKMVAYSSIAHMGYILLASAAATPISMLGTVLQMVSHGLISALLFLTVGVVYKKSGSRNIDVLKGLFNPDRGLPMIGSLMILGVMASAGIPGLAGFIAEFFVFRGSLQVFPVQTLLCMIGTGLTSVYFLIMVNRAFFGRLSDLVVNLPQVRWSDRIPSLILALIILIMGVQPGVILGLSEKTAIAMVTNVPVQVKAIAQNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZK1</accession>
    <name>A0A2G4EZK1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54941">
        <property type="protein sequence ID" value="PHX54941"/>
        <property type="gene ID" value="CP500_013370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="414"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="443"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="489"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="512"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="559" mass="59497" checksum="542EF01403C177E8" modified="2018-01-31" version="1">MTETWQEITQPTWARIAVVSDRLLAQAPPAPNPLGDAERGINNFVQSSNIENLIWAIGILLIGLIVSALVSSLVGGLLKKTTIDNRLAAWITGRPDGESAPQVEKWISAAVFWIIFIFFLIAFFNRLNLTAVSQPLNTFLNQIASALPKLAKALIFLGIAWVLATIAKLAVSRAMRTFSVDERLNQQVGTTPSESPLLLSDTLANALYWFIFLLFLPLILESLELQQALLPVNNLLNQILAAIPKILEALLIGFVGWLLAQVVQRIVTNLLAAAGADSLGARFGISRTAGGQSLSWIVGTIVYVLILIPTAIAALNALDIQAISQPAIAMLNTILGAIPNIFTAAIIIVVAYILGRWIGDLVTNILTGIGFNNVFSWLGAQPKQPLSVTQNQLDTDATVLQSEPQIPARTPSEFVGIVVQVGIILFAVVAATDVLRIPALTAIVSGIVVVAGKVLSGVIVFAIGLYLANLAFSLIASSGTRQARLLGQAARIAIIAFVSALALQQMGIGSDIVNLAFGLLLGAIAVGIALAFGLGGRDIASEQIREWLAAFKQDKTPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZR7</accession>
    <name>A0A2G4EZR7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PBS lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54995">
        <property type="protein sequence ID" value="PHX54995"/>
        <property type="gene ID" value="CP500_013310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="429" mass="46977" checksum="84B9F9266EC64927" modified="2018-01-31" version="1">MFNILEQAQVAADRQNWSELVQCLQQLPMKGHQPLEAQNLEKAVSLAIAVLEYGDFQDRWDVAKILPNLGNGAIAPLINLLEDEDADIEQQWFAARILGKFDRPEVIEALAKLVKNADEELSQIAAETLGNLGPTAVASLATLLLQADSRLFATEALAQIRRSETIAPLLSVVTDSQVGVRFTAIEALSSCHDSRIPPVLVAALKDPATAVRKEAVRALGVRAYLDEEFDLVNLLKPLLWDIRLEVCSEAVIAMGRLKTDAAAAILFELLRSATTPIQLQIETIRALSWMETATALEYLEKALIASNYHIHPTVCQEIVTVLGRWSKPELKSDAAKILINFIESNHPAVEDAGIKQSLALALGQLGDMRALDVLIQLLVNPDNSVRLHSLSALKQLGAGEMRPKLESLLKEDNLGLGLREGIAIALQEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F004</accession>
    <name>A0A2G4F004_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MBOAT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_012735</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55083">
        <property type="protein sequence ID" value="PHX55083"/>
        <property type="gene ID" value="CP500_012735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042121">
        <property type="term" value="P:alginic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024194">
        <property type="entry name" value="Ac/AlaTfrase_AlgI/DltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028362">
        <property type="entry name" value="AlgI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500217">
        <property type="entry name" value="AlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016636">
        <property type="entry name" value="AlgI_DltB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="445"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="471" mass="54458" checksum="A2DCC13FB8626445" modified="2018-01-31" version="1">MLFPTYQFLVFFLIIFSAILSLKHQVNLYKIVLLLSSLLFYSFWSFDFLLLLVLGTAYNYIILRAVCNGKYKKLALISGIIFNIANLGIFKYCNFFVTSLFDVLNQLKIPASFQVLQILVPVGVSFYTFRMISHLIDCYQKKLSCPKFIDYATYITYFPQIASGPISRAPEFYSQLNSSQKYDYQIEEVIVLILSGLFKKYTLSSFLFNFTQLPFKVPQQYSSIDLILAVISYSCLIYVDFSGYSDLANGISCLLGFKPIVNFNMPYQSLSLQEFWKRWHISLSEWLRDYVYIPLGGNKHGKLRKYVNLCCTMAIGGFWHGAGLNFIVWGGIHGLGLVITHLCRDIPQAIHFKLDYLYPKTARFLSWFFTFSFVTGSWVFFGTPNWETAVHLFQGIVHSSVKTFQFNFWQLYLVIAVIGAINFWGDRISQILQIIFSLKNIFFRVVLVSLFVYAILMLGPSTVPPFIYFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F006</accession>
    <name>A0A2G4F006_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aluminum resistance family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55100">
        <property type="protein sequence ID" value="PHX55100"/>
        <property type="gene ID" value="CP500_012560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009651">
        <property type="entry name" value="Met_g_lyase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46658">
        <property type="entry name" value="PTHR46658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06838">
        <property type="entry name" value="Met_gamma_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="410" mass="43699" checksum="EB06C33CA2C91C71" modified="2018-01-31" version="1">MNSVSRLQEAEQALLQIFSGIDATVKQNLQRVLKAFQGHRVGVHHFAGVTGYGHDDLGRETLDRVFAEVVGAEAAAVRVQFVSGTHAIACALFGILRPGDEMLAVAGSPYDTLEEVIGLRGQGQGSLIEFGISYRELPLTREGSVDWQALSSAISAKTRLVLIQRSCGYSWRSSLSISEIKKIVAIVKHQNPNTICFVDNCYGEFVEDCEPTAVGADLMAGSLIKNPGGTIAPAGGYVAGRADLVEMATCRLTAPGIGSSGGATFDLNRLLFQGLFLAPGFVGEAMKGNHLTAYVFYKLGYRVNPIPLAKRRDVIQAIEFGCPDKLIAFCRAVQQNSPVGSYLDPVPGPMHGYDSELVMAGGTFIDGSTSEFSADGPLREPYVAFCQGGTHWTHVSIALEAAIDAVGPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0A3</accession>
    <name>A0A2G4F0A3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_012070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55191">
        <property type="protein sequence ID" value="PHX55191"/>
        <property type="gene ID" value="CP500_012070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="88"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="303" mass="32503" checksum="8F09A351DCACE32A" modified="2018-01-31" version="1">MAVSTKAPPPIPPNSPSKAETVSPWSSWAGPLALLGPSGLWLALLLVVPTIVIFQLSLVPNIKPGDLVIPSGIGNYLRVFEPLNLQVIGRSVFFATGTTILCLVLGFPVAYWIALNVSKKWRNLTLLGFVLPLWTSSLLRSYAWITILRPTGVLNSVLALVGIPPLELLNQSSAVLIGMAYSYLPYIVTILYASLEKLDRRLLEASQDLGANPVETFWQVTVPQTMPGIAAGSLLVFISCLGDFVDPELLGGASSMTAARLIYNQFLGATQNWGLGSALSMVLIFAVSIGIALLLKYGDRNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0D0</accession>
    <name>A0A2G4F0D0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1802 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55215">
        <property type="protein sequence ID" value="PHX55215"/>
        <property type="gene ID" value="CP500_012005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014923">
        <property type="entry name" value="DUF1802"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08819">
        <property type="entry name" value="DUF1802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="485" mass="54530" checksum="10B55C37A8ECFBF0" modified="2018-01-31" version="1">MSYSVFVDTALQLPAPDVEALIEGRVIAAMPRIFIEPGRSFALYLANISINLLPHEQYYRSSFLPIAKTSCSQLSSERVLIKAWAKCELCQILNDPESLEALSQLTVWKTEALQQILLQRRYIFLTHLRVYLLTQPLEMPVHPSGNFVSLPKSLNVTDSTPVLSESIFAKRRQQLEKLEPSEHPELEELQSALVHLSTTNPKAKQLDAEIKIFLGWSSHKPIKPIQLDLAWIKTIAALGDRTKELDTNISNYQAGTDFENVVRDSLEFLGFTIDYAHKGGAGGLDLFCSKPYPLVGECKAGKKIPNDTAVQLLNLGTLRLRDPALLRRVTKLIIGPGEPTPQLKDAAQLHGMAIMNPETLEKLVKLQSNYPNSVDLFKLKEYLKPGKSDDEVAKYIQQVEQEIKVRSQIVQAVKQLCSDNEFPTVVEIKVQYNAKFATDSKLTYESVKDLTIELSSPLTGYLGREKGSDTKSDRFYFLRDLLLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0G9</accession>
    <name>A0A2G4F0G9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55264">
        <property type="protein sequence ID" value="PHX55264"/>
        <property type="gene ID" value="CP500_011750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="16438" checksum="E9B9A186377D6CD1" modified="2018-01-31" version="1">MAYWIKLIYEQNSYIIDLDSISAFSKELDNNRLKFWLPNSSQPIILNSQGNSDTYKQVMDYIIKTIDRNSKKSWIQINYDRKEFSINLSRISFFAYEPNGRLTFCLPDSAINIVISPQINPHDYQKLQEYIRNTTGLSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0M1</accession>
    <name>A0A2G4F0M1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55301">
        <property type="protein sequence ID" value="PHX55301"/>
        <property type="gene ID" value="CP500_011700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="6726" checksum="824676F74746A4C1" modified="2018-01-31" version="1">MRTLLRLTAILTPLSANYVYPFLQLCFLDRISVNLAAKTVAEICTGEWPFAPTDPNALLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0N8</accession>
    <name>A0A2G4F0N8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55323">
        <property type="protein sequence ID" value="PHX55323"/>
        <property type="gene ID" value="CP500_011455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046239">
        <property type="entry name" value="DUF6272"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19788">
        <property type="entry name" value="DUF6272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="192" mass="21474" checksum="205E419FAB08F3C4" modified="2018-01-31" version="1">MIQTFGDFIEPTPSQEYLIIGFSPSSIPLKQRWRNNGLSADFLADYLTIFFPGNQDDDSVLTRQAEIKSAVSYIANELLENAMKFNDENSHYPIDIKLQLEENALIFSVANSIPPLSVGKFQAYIQKLLTCDPSEMYIDQLEKNAADENCSGSGLGLLTMLNDYSAKMGWQFETVQKDPEVIAVTTMVQLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0R1</accession>
    <name>A0A2G4F0R1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sensor histidine kinase KdpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_011365</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55336">
        <property type="protein sequence ID" value="PHX55336"/>
        <property type="gene ID" value="CP500_011365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003852">
        <property type="entry name" value="Sig_transdc_His_kinase_KdpD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02702">
        <property type="entry name" value="KdpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="KdpD" evidence="3">
        <location>
            <begin position="27"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="380" mass="43274" checksum="16847DDC0BBEF81A" modified="2018-01-31" version="1">MIHSSELPNDPNEVYIQPNRTYDRTRRRGKHKIFIGMAPGVGKTFKMLEEGHRLKLEGIDIVIGLLETHGRKETVAKGEGLEIVPRKEMLRGEKMLTEMDAEAVIARHPQLALVDELAHTNIPGSLREKRYQDVELILNAGIDVFSTLNIQHIESLNDLVARITGVVVRERVPDRILEEADEVIVIDVTPETLEERLLEGKIYAPDKIEQSLKNFFQRRHLIALRELALREVADSVEDDAATLKGQSCNIHERVLVCVSTYPNSLQLLRRGGRISSYMNAPLYALFVENPDRFLTKSESLHVETCEKLCQEFNGLFLRVQNQNIAKAISDVAQEYRITQIVIGESQQSRWTLLLRGSLTQQLVRSLKHVDLHIIATEKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Z4</accession>
    <name>A0A2G4F0Z4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55432">
        <property type="protein sequence ID" value="PHX55432"/>
        <property type="gene ID" value="CP500_010850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12812" checksum="C8DF2AD1F853357E" modified="2018-01-31" version="1">MNYTFEILGVSSTLCFFNQQQELLQHQHSAGVEYLGNRKCTLDSFVASVETVSPNRGWDVDGVVDTVISFWMNNSESINYWKCRLQDAGTENLLVARVSDIKSLQAAFESLLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F105</accession>
    <name>A0A2G4F105_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ca(2+)/H(+) antiporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cax</name>
        <name evidence="7" type="ORF">CP500_010855</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55433">
        <property type="protein sequence ID" value="PHX55433"/>
        <property type="gene ID" value="CP500_010855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="PTHR31503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="31"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="222"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="373" mass="39220" checksum="99ADB4E0B972139D" modified="2018-01-31" version="1">MLNTKTILSSLLLFIPISIAGHFLEWESSTIFITSALAIIPLAAWMGTATEEIAVVLGENLGGLLNATFGNATELIIGIVALNAGLIDVVKASITGSIIGNLLLVMGLAMLLGGLRYKEQEFQPVVARLNASAMNLAVIAILVPTAVDVTSKGIDPETMQTLSSAVAVVLILVYVLTLLFSMKTHTYLYDVGVAESEILEGLAENNLAEDNPEHKVNLPLWIGVLVVCTLMVAVESELLVGTLEEATARLGISSLFTGVILVPIIGNAAEHATAVTVAMKNKMDLSVSVAVGSSLQIALFVAPVLVLAGFVLGKPMDLNFNPFELVAVMVAVLIANSISSDGKSNWLEGTLLLAAYVVLGLAFYFHPVIDGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F164</accession>
    <name>A0A2G4F164_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55501">
        <property type="protein sequence ID" value="PHX55501"/>
        <property type="gene ID" value="CP500_010360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="21"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="185"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="226" mass="26391" checksum="78292C32C711DE71" modified="2018-01-31" version="1">MQVTTQEIIYPCSDGEPMAESTIQYKLIVKIKEGCESLFKDDPNVFVAADLLWYPVEGRPDISQAPDTMVIFGRPKGDRRSYMQWQEDNIAPQVVFEIRSHNDRQIKMNKKLSFYNRYGVDEYYLYDPENNDLSGWQRIEGTLEVIEPMEGWSSPRLGVRFELGEDGLEIYRPDGQRFLSYAELEEQGELNRQRAEQAVQRAEQESQRAERLAAKLRELNIDPDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F165</accession>
    <name>A0A2G4F165_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">hisC</name>
        <name evidence="6" type="ORF">CP500_010320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55493">
        <property type="protein sequence ID" value="PHX55493"/>
        <property type="gene ID" value="CP500_010320"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="5">
        <location>
            <begin position="36"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="393" mass="43039" checksum="AB450AAB13F85255" modified="2018-01-31" version="1">MLPFIRKDLAELTAYTPHPGTASAESAQSSMVLDRLDTNECPYDLPAELKQKLAWNYQQLIETNRYPDGGHAALKEAIAQYVNESIPVPPLNKGGLGGVTARNTAITADNISVGNGSDELIRSLLIATCLGGVGSIFVANPTFSMYGIIAQTLGIPVVSAGRKPETFEIDLEMAKKAIDQTENPPVRVVFVVHPNSPTANALTTDEIEWLSNLPEDILVVIDEAYFEFSQNTLAGKLHQHPNWIILRTFSKAFRLASMRVGYAIAHPSLTAALEKIRLPYNLPAFSQLAAEFALAQRQLLLAVISETITERAKLIAALTQYQKLQVWPSAANFVYLRVKADDPNSAEAEHKQIMQQLKTKGTLIRHTGGGLRITVGSPEENQRTCDRIGEILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F176</accession>
    <name>A0A2G4F176_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_010405</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55509">
        <property type="protein sequence ID" value="PHX55509"/>
        <property type="gene ID" value="CP500_010405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="6">
        <location>
            <begin position="183"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="7">
        <location>
            <begin position="317"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="441" mass="49334" checksum="FDBF145D0E066CAB" modified="2018-01-31" version="1">MPQVITAKLKLNLNAEQKALVSQTALAYRDALNYTSQVAFGTGKTSNGLKLQKAVYNELRVRFGLGAQMACNVPRQVSATYKTLWTKVKQSNNAIAKGYTKKRYKGLDKPPKYISRTCTLNYQRDYSFKSEQQVSIITLQGRIVVPYNGYNKHLNLIANGSKIGAAKIVYQRSSKTYYLMVSIEVEVPEINPLKITRVSGVDVGMRYLAVETDLQNKSKFYSGKDARHKANRYHKARQTLQRKGTRSAKRRLIALSGRERRFIADVNHQISKEIAKPNTLIGLENLTGIRDRTKSKSGKKASKKQRRANRNKAKWSFAELHGYIDYKANINSSLATKVPAHYTSKSCPKCGHTSDANRPNKGLLFRCECCGHELHADLAGARNIAMRTLLVRQDWTSTGSLSASPNVSGSETKAEILSRFSELRWSSDTSPHHSGTPLDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F177</accession>
    <name>A0A2G4F177_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,4-dihydroxy-2-naphthoyl-CoA synthase</fullName>
            <shortName evidence="3">DHNA-CoA synthase</shortName>
            <ecNumber evidence="3">4.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menB</name>
        <name evidence="4" type="ORF">CP500_010390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-succinylbenzoyl-CoA + H(+) = 1,4-dihydroxy-2-naphthoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57364"/>
            <dbReference type="ChEBI" id="CHEBI:58897"/>
            <dbReference type="EC" id="4.1.3.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>hydrogencarbonate</name>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; phylloquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 6/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.36" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55506">
        <property type="protein sequence ID" value="PHX55506"/>
        <property type="gene ID" value="CP500_010390"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00995"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008935">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042372">
        <property type="term" value="P:phylloquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01934">
        <property type="entry name" value="MenB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010198">
        <property type="entry name" value="DHNA-CoA_synthase_MenB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43113">
        <property type="entry name" value="PTHR43113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01929">
        <property type="entry name" value="menB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="77"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="121"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Hydrogencarbonate binding" evidence="3">
        <location>
            <begin position="146"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="277" mass="30287" checksum="AA1921B37A400E09" modified="2018-01-31" version="1">MEIEWQTAKTYEDILYHKSNGIAKITINRPHKRNAFRPKTVSELCDAFIDAREDTKIGVVLFTGAGPHTDGKYAFCAGGDQSVRGKAGYVDDGGIPRLNVLELQKLIRSMPKVVIALVAGYAIGGGHVLHLICDLTIAAENAIFGQTGPKVGSFDGGFGASYLARIVGQKKAREIWFLCRQYSAQQALEMGLVNSVVPVEQLELEGIQWASEILDKSPIAIRCLKSAFNADCDGQAGLQELAGNATLLYYMTEEGAEGKQAFLEKREPDFSQYPWLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F194</accession>
    <name>A0A2G4F194_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="8">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_010180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55544">
        <property type="protein sequence ID" value="PHX55544"/>
        <property type="gene ID" value="CP500_010180"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106312">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106313">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0274">FAD</keyword>
    <keyword evidence="5 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="296" mass="32244" checksum="AE5BE9344A5A6C08" modified="2018-01-31" version="1">MNRFRTACSTPGEFIITAEVAPPKGGDMTHTLAMAELLKNRVHAINITDGSRAVLRMSPLAVSVILLQHGIEPICQVACRDRNQIGLQADLMGAHALGIRNILALTGDPVKAGDHPKAKSVFDFEAIRLLQAIQKMNTGTDWNDKPLTDGVTDLFAGAAVDPQCPSWSGLQSRFEKKVAAGAQFFQSQLITDFELFDKFMHHIAAGCNKPILAGIFLFKSAKNAEFIRKNVPGVHIPQETIDRLAKATEPLQEGIKIAAEQVKLARQLCQGVHMMAVKREDLIPQILDLAGIDPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1E7</accession>
    <name>A0A2G4F1E7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MBOAT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_010160</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55583">
        <property type="protein sequence ID" value="PHX55583"/>
        <property type="gene ID" value="CP500_010160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042121">
        <property type="term" value="P:alginic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024194">
        <property type="entry name" value="Ac/AlaTfrase_AlgI/DltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028362">
        <property type="entry name" value="AlgI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500217">
        <property type="entry name" value="AlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016636">
        <property type="entry name" value="AlgI_DltB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="490" mass="56217" checksum="477C46F3408D0867" modified="2018-01-31" version="1">MTFISLQYAQFLLALFVVYWLVPLRWWRLSVMLIASLIFYASLQIWYIPLLLVGTVFNYGLAMAIGEPLDWRIANESWNRRRWLLLWIGISLNVLLLLGFKYVPFFLSSIGNLLSWPVALDGADWVKTHVIAPLGLSFFCFECIAYLIDVYRGAPPSNSLLHFATYKLFFPKLISGPITRYHHLIYQLKSQQFPTVDRMAEGLWSIASGAVKKGLLADNLGIYVDLSFTNLQRAGSEDLWLAIFAYGLQLYLDFSAYVDIARGTALLLGWYLPPNFDFPYFSASIGDFWRRWHMTLGDWLRNYLYFPLGGSRVSLWRTCLNLLIVMLVAGIWHGAAWGFIVWGGLHGLALAVHRLTDVVFKWLRLGFLWESAIGIFIGWLLTQTMVFGSWIFFRLPDLKDSTSVISHLWGHPADVQFAHKVYVEALGLERVQLSWMLGALAVAMLVNYTLIRGLKLELNWPVKLMLVPLCLYAVWVFAPDGGLPYIYFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1F0</accession>
    <name>A0A2G4F1F0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55582">
        <property type="protein sequence ID" value="PHX55582"/>
        <property type="gene ID" value="CP500_010155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="PTHR11364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00380">
        <property type="entry name" value="RHODANESE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="18"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="168"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="273" mass="30294" checksum="095A29B412C84506" modified="2018-01-31" version="1">MTDTNLIVSPEWLAANTENPQVVIIDCRFSLADAELGQKQYQESHIPGAFYLDLNLDLASPVDKHGGRHPLPNIAELADKLSAIGIDFQNTLVVVYDDSRLAFAARLWWLLRYMGHSKVAVLDGGFSGWKAAGYPVTNILPEPREGVFVPELRSNWIVDIEAVKARKDLPGKILVDSRESDRYLGLREPIDPIAGHIPGAVNYPWQDVTDEGSKVRSPSEQKQRWSELETDAEIMVYCGSGVTACVNLLSLEIAGIPNAKLYPGSWSDWCSYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1N3</accession>
    <name>A0A2G4F1N3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplT</name>
        <name evidence="5" type="synonym">rpl20</name>
        <name evidence="7" type="ORF">CP500_009705</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55673">
        <property type="protein sequence ID" value="PHX55673"/>
        <property type="gene ID" value="CP500_009705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="13633" checksum="B1006A44A87BCF7F" modified="2018-01-31" version="1">MTRVKRGNVARARRKKILKLAKGFRGAQSKQFRTANQRVMQALRNSYRDRKKRKRDFRRLWIARINAASRSHGTSYSKLIGNMKKANIEINRKMLAQMAIIDPATFGKVVEMANRAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1N4</accession>
    <name>A0A2G4F1N4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55680">
        <property type="protein sequence ID" value="PHX55680"/>
        <property type="gene ID" value="CP500_009600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="1">
        <location>
            <begin position="1"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="42823" checksum="1AFBA80634DA73F8" modified="2018-01-31" version="1">MLQRLYVNNFRCLENFELLIKGMPSALLIGKNGAGKSTIASALEVLQKICRGTNRMRDLEKLNLISPKDFARGKSDVPIRFEIEVLLEDKLYKYVLALELPEKFRELRVFEEQLLVAGEPIYYRKEAQVTLHTSSQNREAQFMVDWHLVALPVIQKQSETDPLHIFKTWLARMIILAPIPSLMTGDSNGETLEPKRDGSNFGEWISGLLSRYPAAYTQVDKYLREVMPDIQDFLNELIGKDSKSMMVRFEENNANLSIEFNDLSDGEKCFFLCAVVLAANKFYGPLFCFWDEPDNYLSLSEVGHFVMSLRRSFKNSGQILVTSHNEEAIRKFSNENTFILDRKSHLEPTLVRLLSDIPVRGDLINALISGDIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1S4</accession>
    <name>A0A2G4F1S4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phycobilisome degradation protein nblA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55720">
        <property type="protein sequence ID" value="PHX55720"/>
        <property type="gene ID" value="CP500_009310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007574">
        <property type="entry name" value="NblA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036904">
        <property type="entry name" value="NblA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04485">
        <property type="entry name" value="NblA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109859">
        <property type="entry name" value="SSF109859"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="55" mass="6630" checksum="89FD56E4F722CF1F" modified="2018-01-31" version="1">MDMPISLSVEQQFKLQVLREQVKTLSQNEAQEYLLEVMRQNMVKENLLKFWMKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Z0</accession>
    <name>A0A2G4F1Z0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55758">
        <property type="protein sequence ID" value="PHX55758"/>
        <property type="gene ID" value="CP500_009145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="7618" checksum="CFD81C38979B92B6" modified="2018-01-31" version="1">MCRIPPILRYGFAHLSYWELGIGNWELGIGHWALGIGNWALGIGKSYGSRQGALVIVPFDSAQGTMTKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F209</accession>
    <name>A0A2G4F209_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_009000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55778">
        <property type="protein sequence ID" value="PHX55778"/>
        <property type="gene ID" value="CP500_009000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="548"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="590"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="613"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="679"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="6">
        <location>
            <begin position="735"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="260"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="664"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="348"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1013" mass="109425" checksum="2C48EB6B6A56FD7D" modified="2018-01-31" version="1">MAISTNFQQDYQRAEAAYMEGDYQEAAALVYQLVEDFPEDPSARLLCGHIYCYGLEQYEVAREQYTVVLGLSDDFSLVEHAHNGINYTDQFLQAQLPAENFDGETELEFHPEKSLDEDLENPDFELFQGDAAELSWDSESPDGMENEDLLDLGMSDLGWEPPEDHVGDGEDLSLLSNPFTGDSGGIAAYAEATGPLDEFANSDFSDPFALDDEGFDDRFQDQKVSGKSTADYADAFSEAPTQLLNGGGFASAEVGNSIDLNKPDYPTGPSDNFDESFSPRSLPDEFDLDDDLDDYSSPPIGQNHNYEPEEDADPFAQALPSEFGGPETGSEYSSNYDLAEDETLLIGGAVPSSQSQTSSRRGLNSTDRTSQSNGYGDSSSVGFASRDSFELDAFDDDAFNDSFSIDTSEQATSFGAREKQSGDWSSKTVNSQEPSDFLDEFDVFDDLGNLPDFDISEDVNSSILSRGSTNFDNSSTTGMIGTTGGSLDFDNTDGSAIRDDEIFSMSSPADTSPSTFTGTETEAIDSSVTVEQGGLAFLENAPLFTKHFYTAVGAGLVSLIAVAFVTNIASYHALREDKPEAIVYLRQTGWVMTAAAGVTSFLTSLGIGQLIAKQVRNSSDNLQAQFDAVSQGNLDARAIIYSEDEFGKMAAKFNHMAKVIQTTISDTRRKSDEQEQAKEDLQRQVIRLLDDVEGAARGDLTVTAEVTADVLGAVADSFNLTIQNLREIVHQVKQAAREVSKGATDSAKFAGDLSSDALRQAEELAATLNSVQVLTDAIQRVAESAREAEEVARGAAATALKGGEAVERTVAGILEIRETVAETTRKVKRLAEASQEISKIVALIATIASRTNLLALNASIEAARAGEAGRGFAIVADEVRQLADRSAKSLKEIEQIVMQIQSETGAVMTAMEEGTQQVIEGTKLAEQAKRSLDDIIQVTNRIDVLVRSITADTVEQNETARSVAAVMEAVELTAQETSQEAQRVSGALQNLVGVARDLLTSVERFRVETAERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F218</accession>
    <name>A0A2G4F218_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55814">
        <property type="protein sequence ID" value="PHX55814"/>
        <property type="gene ID" value="CP500_008635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="93"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="415" mass="46705" checksum="6331A97A318C14BF" modified="2018-01-31" version="1">MAIKVMEIEFTEEINPIRQLEEYEGVRILVCYRGRPRGWAYVSNNPWEQTISADRVRQTIVDQLGKELVRSTLREEFGAVSEAVTDRHLPPISVVICTRDRTDLLKGALEAILALDYPHREIIVIDNAPANNSTAELVALLPVRYVKEERPGLDWARNRGIAEARHEIIAFTDDDVRPDRGWLRGIAAGFADPEIMAVSGLVAAAELETVAQQQFELIYGGMLQYLDSRKTNGSELSVQELLWASNYGVGANMAFRRQVFETVGNFDVALDVGTATRGCGDIEIFHRILAKGYATVYEPRAFVWHLHRRTDKALSKQLQDNGRGFGAYLLTCDRNRTVPRLEILKFAMFNWFGWWLVRRLKTPGLLPRHLVVSELLGALGSPFAYGKAQLQAQQLAELEPQEQPQPAQPVVGGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F261</accession>
    <name>A0A2G4F261_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Phycoerythrobilin:ferredoxin oxidoreductase</fullName>
            <ecNumber evidence="4 7">1.3.7.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pebB</name>
        <name evidence="8" type="ORF">CP500_008500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(3Z)-phycoerythrobilin + oxidized 2[4Fe-4S]-[ferredoxin] = 15,16-dihydrobiliverdin + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22092"/>
            <dbReference type="Rhea" id="RHEA-COMP:10002"/>
            <dbReference type="Rhea" id="RHEA-COMP:10004"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:57438"/>
            <dbReference type="ChEBI" id="CHEBI:57899"/>
            <dbReference type="EC" id="1.3.7.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the HY2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.7.3" evidence="4 7"/>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55863">
        <property type="protein sequence ID" value="PHX55863"/>
        <property type="gene ID" value="CP500_008500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050618">
        <property type="term" value="F:phycoerythrobilin:ferredoxin oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010024">
        <property type="term" value="P:phytochromobilin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00793">
        <property type="entry name" value="PebB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009249">
        <property type="entry name" value="Ferredoxin-dep_bilin_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022827">
        <property type="entry name" value="Phycoerythrobilin_Fdx_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34557">
        <property type="entry name" value="PTHR34557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05996">
        <property type="entry name" value="Fe_bilin_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="243" mass="27989" checksum="91606B6EBA8AFAF0" modified="2018-01-31" version="1">MTLYQPFLDYAIPLLTERLDLAPYPIPAGFESKECITGKGKKEQLVVTTSHAFKSSKLRQIRAAHVQGGDALQVLNFVIFPQINYDLPFFGADLVTLPGGHLIALDMQPLFHNPAYQKQYSDPILPIFNKYQKDLPWGGDFPEEAKQFFSPAFLWTRPKETEAVQTTVFAAFQDYLQAYLDLVDRAQPVTDSQRLAEILQAQRNYINYRAAKDPARGMFLRFYGEEWTEEYIHGFLFDLERHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F290</accession>
    <name>A0A2G4F290_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
            <shortName evidence="7">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">serS</name>
        <name evidence="9" type="ORF">CP500_008335</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55893">
        <property type="protein sequence ID" value="PHX55893"/>
        <property type="gene ID" value="CP500_008335"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="178"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="7">
        <location>
            <begin position="235"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="266"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="353"/>
            <end position="356"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="426" mass="47546" checksum="E9226E8BFAD6D7CD" modified="2018-01-31" version="1">MLDLKLIRENPQAVQESLNTRGGNYEIEPILQLDKQQRELESRRSQLQARSNEIAKLIGQKRKAGLTLESPEVHQLQAEGNAVGTESNELQAQEKDLKAQIEALLLPLPNLPDKSTPIGKNENENVEIRKWGDEYIPQNSGILPHWEIGEKLGILNFERAVKISQPRFVTLIGAGAALERAIIQFMLDRHTKAGYVEVIPPLLVNTESLTATGQLPKFAEESFKCDQDDLWLIPTSEVPVVNLYRGEILTAEQLPIYHCSFTPCFRREAGSYGKDTRGLIRLHQFNKVELVKLVHPSTSEVEHEKLVQDAEGVLQALKLPYRAIALCTGDLGFAAAKTYDLEVWLPSAGKYREISSCSNVADFQARRANIRFKEAGKKGTQFVHALNGSGLAVGRTMAAILENYQQPDGTIKVPEVLQPYLGREVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2C5</accession>
    <name>A0A2G4F2C5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">msrA</name>
        <name evidence="6" type="ORF">CP500_008330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55892">
        <property type="protein sequence ID" value="PHX55892"/>
        <property type="gene ID" value="CP500_008330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="49"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="217" mass="23636" checksum="498E0055405B4A42" modified="2018-01-31" version="1">MALFGFGKKSSLPSAQDALPGRAQSMSVSANHFVNGNPIKPPFPTGMETAMFGLGCFWGAERKFWQEKGVFSTAVGYAAGSTPNPNYNEVCSGMTGHNEVVLVVFDPKTISYETLLKVFWESHNPTQGMRQGNDSGTQYRSGIYTYSPSQMQLAEASRDAYQQALTPAGYGKITTEIIEAPEFYYAETYHQQYLAKNPNGYCGLGGTKVCLPAMSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2S3</accession>
    <name>A0A2G4F2S3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56049">
        <property type="protein sequence ID" value="PHX56049"/>
        <property type="gene ID" value="CP500_007400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="31"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="283" mass="32040" checksum="5B3A6F00D017CEF3" modified="2018-01-31" version="1">MSIDEKVIEVGPLQWFYRETNPVSETEKPPVLLLHGLPSQSFTWTAIMPDLATNGFRAIAPDWIGYGRSTKPDKRDFAYTPDAFVEALAGFIQALEIDRFYLVVQGFLASAGIQYAMRNQDKIERLVVINTPVSADIKLPWKMQQLGLPFIGDMITQDPLLVDRTLEGGCRQIISDNDLDVYRRPFLKSSDAGRSLMNTVRNIQLPQSMAEIESGFPGWTRPTLFVWGLTDPWLSVEPAQKLVISMQNAELLTLEQAGHYPQEHWSEKVGDGLIDFLRRKEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Y6</accession>
    <name>A0A2G4F2Y6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56105">
        <property type="protein sequence ID" value="PHX56105"/>
        <property type="gene ID" value="CP500_007305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="80" mass="8685" checksum="512A707DA262746B" modified="2018-01-31" version="1">MQELLAVAQGNVRLFAFVGGDVSGVVVAQAFVNGLENMQRFIRGNQAPFIAKVHQSGKVTSCKNQKELLKKLPKKASLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F388</accession>
    <name>A0A2G4F388_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_006525</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56216">
        <property type="protein sequence ID" value="PHX56216"/>
        <property type="gene ID" value="CP500_006525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009740">
        <property type="term" value="P:gibberellic acid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="28"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="25"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0939">Gibberellin signaling pathway</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="50"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="84"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="118"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="152"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="186"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="220"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="254"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="594"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="628"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="662"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="696"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="730"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="764"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1124"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1158"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1192"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1226"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1260"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1294"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1328"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1719"/>
            <end position="1752"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1753"/>
            <end position="1786"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1787"/>
            <end position="1820"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1821"/>
            <end position="1854"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="1855"/>
            <end position="1888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00019143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1905" mass="211375" checksum="CFA3CA6340D909CD" modified="2018-01-31" version="1">MASENKSRQSVSKMSAEDSLKIAWEHHQAGRLLEAESLYRQVIAVHPESANVLCLFGIAVRQQGKIEEAIAFYEQAIAQQPDFVEAHLNKAHVLLDIGEHQSAIACYEQVIQLAPNSALAHKNLGWLKQQVGDIDGAIDSYQTTLKLEPNGSETAHNLGNIFKEKGQTQEAIACYKKALEINPNSIHSIIGLGTVLQQQGQSIEAIDCYQQALKLDANNAECFNNIGAVYHEQDKTQLAISYYQQALNLKPDFVDAINNLGHAFVDLGQFKSALSCHYRALELQPENSTAHLEYALTLLLFGDFRRGFAEYEWRWRTSQLKPRQFAQPVWDGSSLQGKTILLHVEQGFGDSIQFIRYAPILSSQGAKVIVACYPELMRLFATVASIEYLSVSFENLPAFDVYAPLMSLPRILDTTLETIPANIPYLTPPAECNFALSSDAKLKVGIVWAGNPKRRKDNQRSCNLSDFMHLLDIPGIAVYSLQKNLSEADRTLLNQHLVPDLSPHLNDFADTASAISQLDLVISVDTSVAHLAGALGKPVWVLLSFAPDWRWLLDRDDNPWYPTARLFRQSQPENWQELFEEVKAALSLLVASNIETQLQQAESLMEIGDKEEAIALYEQIISLAPNCVQARINLGFLQQEKGELDAALPHYREALKIDPNIPQTAYNLAKVFEEKGQSKEAIEHYQQALVAQPDFVPALINLAVALQEKGELLEAVNLYRRALEVEPHSWEALNNLGTVLQEQGNLEEALEYYHKALELLPDFVEAINNLGRTFLEKGAVEDAIACYRRVISLSPEHASAHLNVSLALLLAGDLENGLAEYEWRWQIKEFQTGHSSFLTGPDNTVAAREYRPLWDGSDLQGKTILLHAEQGLGDSIQFVRYAAIVQSKGGRVIVGCYSQLTRLFSTVSGIDLVIVKGELIPAFDVQVPMLSLPYILGTTLETIPGNTGYLKVPADCEFALLPDRKFKVGIVWAGNPKHRKNTQRSCSLSAFIPLLDVSGVSFYSLQKELSEADRALLHQTSIVDLSPHFGDLADTAAAIAQLDLVITVDTAVAHLAGALGKPVWILLAFSPDWRWLLEREDSPWYPTARLFRQSIRGDWKGVFERVTEALENAVSQEFVQADLADAELLLGRDLQQQGEFRGAIECYERAIAIAPNNAIAYSNLGVIKQQQGELVEAIAYYRKALEIDPNLAEILSNLGSALADAGETEEAIAVYDRALSLNPNCAEAWINLGLARENQGDLVEAINCYQQGIQLNPNSAEAYLNLGIALEEQGKLDEALVVCQQAIQQFPANVDAHNNLGMVLYKQGKFENAIACYQQVLNLKPDFLQALNNLGKAFEEVGKLANAIDCYHRAIELQPNNINSFNGLGNALQKQGKFTDAVACYSQGVERNITHPEAHLNLALALLLVGDFQRGFSEYEWRMLVKEKQFPTNNFPQPLWDGKDLNGKTILLCLEQGLGDAIQFIRYADLVKQKGGKVIVWCLPHLQRLFEQVSGIDQLIVSPESAPDFDVRAQLMSLPHLLGTTSASIPAKVPYLAPPPGVEFTINETHNLKVGIVWSGNPQNSQNKLRSFPLNSLLKLLDIPGVDFYSLQKDIPEEEASWLEQMQIADLSPYLHDFADTAAAILALDLVISVDTSVAHLAGALGKPVWILLCFTPDWRWMLEGEESPWYPTARLFRQEKLGDWEGVFERLALALKAQICQHQPEPILMENQPNLELAKKQFNRGNILKSQGKFTEAIAYFKNALVCQPDLIEAATNLAVTLHQIGDLTEAATYYLRSIEIDPNSAQAHNNLGILRQAQGNIVEAVSCFQQAIALNPLYVKALNNLGALLQQQGELPGAIACFQQALSATSNYVPALVNLGVAMEAKCQPEEAKRYYKQSIDLEPDNPKSHCYLGTLRQFGQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3A4</accession>
    <name>A0A2G4F3A4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase</fullName>
            <shortName evidence="6">Mg-protoporphyrin IX monomethyl ester oxidative cyclase</shortName>
            <ecNumber evidence="6">1.14.13.81</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">acsF</name>
        <name evidence="8" type="ORF">CP500_006430</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>2 H(+) + Mg-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 O2 = 3,8-divinyl protochlorophyllide a + 5 H2O + 3 NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:33235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58632"/>
            <dbReference type="ChEBI" id="CHEBI:60491"/>
            <dbReference type="EC" id="1.14.13.81"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; chlorophyll biosynthesis (light-independent).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AcsF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.81" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56242">
        <property type="protein sequence ID" value="PHX56242"/>
        <property type="gene ID" value="CP500_006430"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00670"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048529">
        <property type="term" value="F:magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036068">
        <property type="term" value="P:light-independent chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01047">
        <property type="entry name" value="ACSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01840">
        <property type="entry name" value="AcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008434">
        <property type="entry name" value="AcsF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003251">
        <property type="entry name" value="Rubrerythrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31053">
        <property type="entry name" value="PTHR31053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02915">
        <property type="entry name" value="Rubrerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02029">
        <property type="entry name" value="AcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rubrerythrin" evidence="7">
        <location>
            <begin position="89"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="358" mass="42409" checksum="32468C5BE4065D04" modified="2018-01-31" version="1">MVDSLRKPTFAETQQEAKVPAKETILTPRFYTTDFEEMAKMDISINEAELEAIIQEFRVDYNKNHFVRDEEFAQSWDHIDGEKRRLFIEFLERSCTAEFSGFLLYKELGRRLKGKNPVLAEGFLLMSRDEARHAGFLNKAISDFDLSLDLGFLTKSRSYTFFKPKFIFYATYLSEKIGYWRYITIYQHLKAHPEHQIYPIFRFFENWCQDENRHGDFFDAVMRAQPQMLNDWRAKLWCRFFLLSVFATMYLNDIQRGGFYRSLGLDAREYDIEVIKKTNQTAGRVFPVMLDVNNPEFYERLDVCLKNNQELTAIVASNTPKFFQLFQKLPLYLSNGWQLIKLYFMKTIDSPSVEGAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3J8</accession>
    <name>A0A2G4F3J8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56332">
        <property type="protein sequence ID" value="PHX56332"/>
        <property type="gene ID" value="CP500_005985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="80" mass="9132" checksum="215A69B16F7C534A" modified="2018-01-31" version="1">MTYGEGSSATDYVTDLTDVTEVGLNHILHHSQQDFYEQAFRPVSQQDSLFVEQTEKPVVGNSGRCELELSRSVTFYYYCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3M0</accession>
    <name>A0A2G4F3M0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA sulfur modification protein DndD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dndD</name>
        <name evidence="3" type="ORF">CP500_005820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245725">
        <property type="entry name" value="M.Tbo703DndDP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56360">
        <property type="protein sequence ID" value="PHX56360"/>
        <property type="gene ID" value="CP500_005820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017599">
        <property type="entry name" value="DNA_S_DndD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03185">
        <property type="entry name" value="DNA_S_dndD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="6"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="232"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="434"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="664" mass="74876" checksum="623C27945D7D9CCB" modified="2018-01-31" version="1">MQFLELVLKNFGPYAGTQTINLRPEKDGNPCPIVLFGGMNGGGKTTLLDAIRLALYGGRAQCSTRGNLSYSDFLNQSINRQTPPFEDTRVELIFEQIQDDKLTKFKIVRYWKPADTKDTLSILIYSEVVTDWWADKAISNTWDEYIETLLPVGISNLFLFDGEQVKELAELETPPEFVVGAIKSLLGLELAERLAVDLEILAGRKRKEIAGKKDLATLEKIEGIFKEITAKKDLETEKQASFKNQLEKAQKNQQQASDKFISEGGKIAADRSQLDIQLNNYKNQAEKTRQAMMELASNTLPLALISPLLTAAKTQAETEASQQQAKIAQEVIKQRSDRLLNYIAEISLNPAQLDKIQDFIRQEDKELEQQAGTDISPWMNADDNSIQQLENLLSYQIQAQQIATAQQIAEIKNIESEIDFTDRQLAAAASPEAYDKLELAVKNAQKAVANAAADVESANRRIDELDKELAKNQKELETYSSEYITIRNSQHIIASIAKAQATLKQFKEKLTLKKLNKLEVEITDCFRYLLHKTDLVHRVAIDTQTFSLSIYDTEGKLVPKHRLSAGEKQLLAIAFLWGLARVSGRLLPVAIDTPLGRLDSSHRNNLVERYFPSASHQVILLSTDTEISKVEYDKLQELEAIAHSYLLKYDSTKRQTTVEKGYFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3R4</accession>
    <name>A0A2G4F3R4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4330 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56386">
        <property type="protein sequence ID" value="PHX56386"/>
        <property type="gene ID" value="CP500_005585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025480">
        <property type="entry name" value="DUF4330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14221">
        <property type="entry name" value="DUF4330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="175" mass="18665" checksum="C8340A32CD27381B" modified="2018-01-31" version="1">MKMLDSQGRLFGKLSILDLGAALIILLVAVGIFFFPGASGGSVAQVGGASVKAVEIDAIAIGLKGTNFQELFKAGDKINVIIRNQPSGQITLKSVKTLTRTLAVTQPNGMLKALPDPREEESFSRNMMFTLEGKGQVTENGPVLGNTKVKIGTTLELEGKKYIFNASVIDVRVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3T3</accession>
    <name>A0A2G4F3T3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56420">
        <property type="protein sequence ID" value="PHX56420"/>
        <property type="gene ID" value="CP500_005280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="PTHR13355"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="18671" checksum="0C4AAD3576F5F69A" modified="2018-01-31" version="1">MTSTTRDSSHIQFCTGHNRVDLEQLQHLFKVAAFWARERKSEDWKIAIANSEPVVTVWDKERAIGFARATSDGIYRATIWDVAIHPDYQGSGLGRKLVETVLSHPRMSRVERVYLMTTYKQSFYERIGFQYNASTTMVLENQPLEENIELEIINSELVIGNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F418</accession>
    <name>A0A2G4F418_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_005205</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56488">
        <property type="protein sequence ID" value="PHX56488"/>
        <property type="gene ID" value="CP500_005205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="AA_permease" evidence="6">
        <location>
            <begin position="14"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="423" mass="44755" checksum="6D2CA7C99A706E8A" modified="2018-01-31" version="1">MSSPLLKRELGIFGATLMGLGSILGTGVFVSIGIAAEIAGPGVIFAVIIAGLVAVCNGLSSAQLAANHPVSGGTYEYGNKYLNPWLGFTAGWMFLLAKTASAATAALGFAGYFLNAVGVADRTYLILTALVALATLTLVVLTGIRRSSIANTVIVSVTLLSLVVFIFAGLPEVSWTLATVQNDSSIASILHATALIFVAYGGYARIATMSEEVREPRQTIPKAIIFTLVLTMLLYMAVAIVFVGVGGVDKLSLQTAITAAPLEIVARSFRIPGVSQLLAVGAITAMLGVLLNLILGLSRVLLAMGRRLDMPRVLARLDSSGTTPYVAVVAVEVAIALLILVGDVKTTWSFSAFTILIYYTITNLAALQLSPTERLYPQWLAVVGLGSCLFLAFWVQRQIWLIGLTLIMAGLIWRAIVRLLTKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F458</accession>
    <name>A0A2G4F458_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptide ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56529">
        <property type="protein sequence ID" value="PHX56529"/>
        <property type="gene ID" value="CP500_004975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="1">
        <location>
            <begin position="75"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="586" mass="66276" checksum="36EC403E0E969657" modified="2018-01-31" version="1">MMLHSKLRSLIILLAAIVTIALSACTPARSQLTNRLIVPTPSGPATFNYPLNQSAYSVFGYLNEGLINENGLTSELEPGLAESWEVSKDGKKIVFTLREGLKWSDGEPMTTDDIIFSYDKIYFNDKIPSGLKDTLRVGMSRQFPKLKKLDSRLVEFSVAEPFAPFIRYAGGIPILPAHILQESISNTDSEGKPKFLSTWGTDTDPKKIVGNGQYRMLSYTPNQRVVLERNPYFWRKDTQGTTQPYIQQIVWQIIENTDTQLLNFRSGDLDSLEVQPEVFPLLKREEKRGKYTVFNGGPDTGSVFMCFNLNKGRNPQKQPFVDPIKSRWFATKEFRQAIAYAINRDAMTNNIYRGLGAPLHSPIPAQSPFYLSPKEGLKTYSYDLQKAKDLLLSAGFKYNTEGELLDTEGNKVRFTLLMAAGKKVREQMGTQIKQDLGKLGMQIDTQFLSFNTYVEKLRLSKNWDTYLGGFTGGLEPHSGYNIWSVNGTLHSFNQGPQAGEPPIKGWEVAEWEQKIDDLYVKASQELDEAKRKELYGETQKIIAEQVPFIYMVNPLTFEAVRDRISGIKYSAIGGAFWNLYELKIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F460</accession>
    <name>A0A2G4F460_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleic acid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56501">
        <property type="protein sequence ID" value="PHX56501"/>
        <property type="gene ID" value="CP500_004920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="141" mass="16273" checksum="5BE6FC0AFDDDE722" modified="2018-01-31" version="1">MTQYILDTDHITLLQHSNPLILQRFETLHTSDVAITVINVEELIQGWFNAIRQASQPGQQQRLTWAYVGLRSAVKFLNDFLVLDFTESAYEQYLALRRQGIRIGTQDLRIASIALVNNLILVTRNRQDFAQFPGLVLEDWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4A6</accession>
    <name>A0A2G4F4A6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56317">
        <property type="protein sequence ID" value="PHX56317"/>
        <property type="gene ID" value="CP500_006065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="290"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="370" mass="40413" checksum="FCD2EFEE7F4A45B4" modified="2018-01-31" version="1">MNNASPLIQTITPERWAGLSMDFIGAGYAGLLVKNGRVVRTLKSGRHFTFALPLLEQCQIVIVDTKLRNLDVQSQGDFLSKDRFLIDATLTVIYQVIDPKRVALELSDPIAALASAVKDCMGVAIGQIPLNQLISQGRLLLRQNLLDRVQDFYTLGFTLEDVRIGDVSFPETNGVIRQVEGMSYRQEAENSAALQMRIAEAGRPIQPQAPVQQLNLISGQSPVSLPASDSAGFDRDLQQLTAQLAQNSLPAAQNRPQLAPTVLASSDRQTSAYLVYKLSGEAIGLTVNPFTIGREPGNTLVLQDPQSSRYHAQIRRATDDQGKQRYQLVDCGSSNGTFVGGQRLAANDPFWLTNGCEIAIGDQKWTFQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4K6</accession>
    <name>A0A2G4F4K6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56686">
        <property type="protein sequence ID" value="PHX56686"/>
        <property type="gene ID" value="CP500_004115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="205" mass="23693" checksum="F318A806FCFD654E" modified="2018-01-31" version="1">MTKQKILDEGREYTFRSYFELPYETDQILAEFDYSLIVGNLSLPHTSKQLAEIASLKQRITATLPFVSLSSETARRESLVSPILLDLVRYCQCQLRFEYTLNVNSWLKGNLDYLVKSNQELLVIEAKNDDMTRGFTQLAVQLIAMSHVEDQNIFYGAVTMGEVWRFGKLDRNQKTIFRDIHLFRVPDDLDDLLKVMVGILDGDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4L1</accession>
    <name>A0A2G4F4L1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Group II intron reverse transcriptase/maturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ltrA</name>
        <name evidence="3" type="ORF">CP500_005325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56427">
        <property type="protein sequence ID" value="PHX56427"/>
        <property type="gene ID" value="CP500_005325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025960">
        <property type="entry name" value="RVT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13655">
        <property type="entry name" value="RVT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="2">
        <location>
            <begin position="91"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="557" mass="63760" checksum="54B92C178C75EBC2" modified="2018-01-31" version="1">MNKSKTRDNPTVEWNQINWRKAERLTFKLQKRIYRASERGDVKAVRKLQKTLINSWSNKVLAVRRVTQDNTGKRTAGVDGIKLLTPKQRLELVSQLKTTGKSQPTRRVMIPKPGTNESRPLGIPTMYDRALQAVVKSALEPEWEARFEPNSYGFRPGRSCHDAIGAIFDSIRYKAKYVLDADIAKCFDRINHKALLDKINTYPGLRRQIKSWLKSGVLDQGEIFPTKDGTPQGGVISPLLANIALHGMEERVKQFVGNSISRRNEISLIRYADDFVIIHKDIEVILACQKIIAEWLSDLGLELKPSKTKLTHTLNEYNGNVGFEFLGFHVQQHKVGNYRSAKNTHGIPLGFKTLITPSKPKVKAHLVKIEKVIDTHSHSPQYALIKRLNPIIRGWSNYYSTVVSKETFNKVDNLTYDKLRAWARRRGKGSINKDKYWRTVGDRNWCFSTEEGLELTQHQATPIIRHVKVKGNSTPYDGDWIYWSKRRGEYPETPTRVATLLKAQKGKCTHCGLYFTPTDTVEVDHIQPRSLGGKDEYKNLQLLHKHCHDTKTENDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Q0</accession>
    <name>A0A2G4F4Q0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56719">
        <property type="protein sequence ID" value="PHX56719"/>
        <property type="gene ID" value="CP500_003655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="478" mass="50354" checksum="F023D2DFD36523C8" modified="2018-01-31" version="1">MEMNVGDFLNRLDLRGQALKGINLSGAELRGANLRGTDLRETNLSEAILRYADLIEADLTGANLRGADLAESFLNLANLTRADLTGAVLREATLVGAELFGTNLQQASLIKANLVGANLAEANLNRANLSGADLRGAQLLDTILDKAVYNNRTVFPHDIDPAAMGALLLGPNASLPGLNLSMVDLTGVDLKGADLRRTNLCDAILFGAKLDRANLTGANLSGADLREANFSSTILEKVVYSNKTLFSEGIDLSIAGAYLIAPNVSLQGLNLTGADLSGSDLSGANLSGSNLSSVNLKNVDLSRASLKKAYLKGANLEGTDLRGADLTGAILHQVNLISADLRGVDLTRADLTGANLSNADLRETDLTGSTLLFANLSGADLRGVDLTKADLSGANLNEADLRKADLMRVNLEGADLTEVDLSDAHLFRVNLKGANLKGANLKGASFKLVFLNDAHLSETDLTDVEFSPSFFEIPLESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4X0</accession>
    <name>A0A2G4F4X0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zeta-carotene desaturase</fullName>
            <ecNumber evidence="5">1.3.5.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">9,9'-di-cis-zeta-carotene desaturase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">zds</name>
        <name evidence="7" type="ORF">CP500_003400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>9,9'-di-cis-zeta-carotene + 2 a quinone = 7,7',9,9'-tetra-cis-lycopene + 2 a quinol</text>
            <dbReference type="Rhea" id="RHEA:30955"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:48716"/>
            <dbReference type="ChEBI" id="CHEBI:62466"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Carotenoid biosynthesis; lycopene biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the zeta carotene desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.6" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56789">
        <property type="protein sequence ID" value="PHX56789"/>
        <property type="gene ID" value="CP500_003400"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00803"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052887">
        <property type="term" value="F:7,9,9'-tricis-neurosporene:quinone oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052886">
        <property type="term" value="F:9,9'-dicis-carotene:quinone oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016719">
        <property type="term" value="F:carotene 7,8-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014103">
        <property type="entry name" value="Zeta_caro_desat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02732">
        <property type="entry name" value="zeta_caro_desat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="6">
        <location>
            <begin position="10"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="478" mass="53089" checksum="4B916008E94BE369" modified="2018-01-31" version="1">MRVAIAGAGLAGMTTAVDLVDAGHEVEIFESRPFVGGKVGSWVDPDGNHVEMGLHVFFGCYYNLFALMKKVGAFDDLLLKQHVHTFINRGGETGSLDFRFPVGAPLHGLKAFFTTSQLSVQDKIQNSIALGTSPIVRGLIDFDGAMKTIRNLDKISFADWFRSHGGNQNSLKRMWNPIAYALGFIDTENISARCMLTIFQFFATKTEASMMRMLAGSPSEYLHKPIVEYLESKGTKIHTRRRVREIQFQEGAETRVTGLAVASGETEEIITADAYVFALDVPGIQKILPPAWRKWSEFDNIYKLDTVPVATVQLRFDGWVTELEDEAKRKQLSHAVGIDNLLYSADADFSCFADLALTSPKDYYKEGEGSLLQLVLTPGDPFIKQSNEAIAQHVLKQVQDLFPSARELNMTWYSVVKLAQSLYREAPGMDVYRPAQKTPIANLFLAGSYTQQDYIDSMEGATLSGHQAAKAILEAYSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4X3</accession>
    <name>A0A2G4F4X3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_003220</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56822">
        <property type="protein sequence ID" value="PHX56822"/>
        <property type="gene ID" value="CP500_003220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16383">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008629">
        <property type="entry name" value="GUN4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037215">
        <property type="entry name" value="GUN4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05419">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140869">
        <property type="entry name" value="SSF140869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="34"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="480" mass="54163" checksum="5D5CB0E4869844C0" modified="2018-01-31" version="1">MSQCLNPDCLNQNPSGTTNFCQKCGNKLLLGDRYRARKIIGQGGFGRTFLAVDEYKPSKPPCVIKQFYPQAQGTSSIQKATELFELEAVRLEQLGKHPQIPDLLAYFSQDGQQYLVQEFIDGENLAQALKSEGYFSETQIRDLLNNLLPVFEFIHSRQVIHRDIKLENIILRSNRELVLVDFGAAKYATQTALAVTGTMIGSAGYTAPEQAAGKAIYASDIYSLGVTCLCLLTQVEPLELFDVSEFEWVWREHLKTSVSSELGQILDKMIQPASKKRYQSATEVLQALGNQLTQTPPPKPSPKSSPQSSPDLLKSARGVDYTRLRDLLTTGEWKEADRETFKVMLKAASREKEGWFHTNSIENFPGDDLRTIDQLWVKYSQGHFGFSVQKKIWLEVGGKVDYDTECKLGDRVGWRKRRKGRKDWLKYDDLTFNLKQAPPGHLPSCARVFAWEGEGLGWVVGVLGWLGLVVWFSLLSHQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Y4</accession>
    <name>A0A2G4F4Y4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56785">
        <property type="protein sequence ID" value="PHX56785"/>
        <property type="gene ID" value="CP500_003375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="87" mass="9884" checksum="C547433D18371FE7" modified="2018-01-31" version="1">MPKYLTITEAQQQLPKWPDDLATEPAIITKDGKPAIIALSFKQFESLLETIEILSDREFMADLRSGIQQVQRGETIDLQQLKADLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F514</accession>
    <name>A0A2G4F514_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit J</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I subunit 6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56815">
        <property type="protein sequence ID" value="PHX56815"/>
        <property type="gene ID" value="CP500_003435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001457">
        <property type="entry name" value="NADH_UbQ/plastoQ_OxRdtase_su6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042106">
        <property type="entry name" value="Nuo/plastoQ_OxRdtase_6_NuoJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00499">
        <property type="entry name" value="Oxidored_q3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0874">Quinone</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="208" mass="22234" checksum="18FA31F17205B89F" modified="2018-01-31" version="1">MNLAEGVQIVSFGILSVMMIGGALGVVLFSNIVYSAFLLCGVFTSIAGLYLLLNADFVAAAQILIYVGAVNVLILFAIMLVNKREEFRKIPNAWVRQVATAVVCGGLFALLGTMVVSTPWAIVATTGAPPAESSIVTIAKHFFTDYLLPFELASLFLLMAMVGAIVLARRDFFPDELANKLSETPAFSLPERPRELVSAGDASSPESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F557</accession>
    <name>A0A2G4F557_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Deoxyribodipyrimidine photolyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_003070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DNA photolyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56869">
        <property type="protein sequence ID" value="PHX56869"/>
        <property type="gene ID" value="CP500_003070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00691">
        <property type="entry name" value="DNA_PHOTOLYASES_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="6">
        <location>
            <begin position="3"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="483" mass="55749" checksum="E683B2A81DC105AE" modified="2018-01-31" version="1">MSDLILFWHRRDLRIYDNIGLAAARQQSPKVVGIFCLDRNILDLDEVAPARVTYMIGCLQKLQQSYVESGSQLLIIQGEPTEGIPRLATAINAKAVFWNLDVEPYAKKRDLAVSNALQEAGITIENFWDQLLHAPDEIRTGAGTIYTVYTPFWKRWNSKPKTQPVETLPVISLELMVGLTSEEQELAYQAGAIQVLPSASDLGFVWESPLLIEPGEDAAREKLEEFCDRTIYEYQEKRNLPTVNGTSQLSPALKFGAIGIRTVWQATQIVMDNCRNEETRTNIRTWQQELAWREFYQHAMYNFPELADGPYRQAFKDFPWENDEKIFQAWCRGKTGYPIIDAAMRQLNQTGWMHNRCRMIVASFLTKDLIINWQWGEKYFMQKLIDGDLSANNGGWQWSASSGMDPKPLRIFNPASQAQKFDPEGEYIRHWVPELRRVDTKLLLTGNIPPLVRKTLPYPDPIVDHNEQQRKFKELYKQQKIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F596</accession>
    <name>A0A2G4F596_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_002835</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56930">
        <property type="protein sequence ID" value="PHX56930"/>
        <property type="gene ID" value="CP500_002835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="32"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="11659" checksum="350CDDD48E6DFCA4" modified="2018-01-31" version="1">MSAAAQVTDSTFKQEVLDSEIPVLVDFWAPWCGPCRMVAPVVDEIAQQFEGQVKVVKVNTDENPNVATQYGIRSIPTLMIFKGGQRVDMVVGAVPKTTLAKTLEGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5A2</accession>
    <name>A0A2G4F5A2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56964">
        <property type="protein sequence ID" value="PHX56964"/>
        <property type="gene ID" value="CP500_002440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8029" checksum="4960D6A233E28508" modified="2018-01-31" version="1">MGDLVGQVEDFQKTLNQIMELMDDAKSQAGQLPDATLAEARSKVQQIYEICDEAIKTLNVATGQAEEIMKTVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5B5</accession>
    <name>A0A2G4F5B5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alanine--glyoxylate aminotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_004070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56677">
        <property type="protein sequence ID" value="PHX56677"/>
        <property type="gene ID" value="CP500_004070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="26"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="385" mass="41575" checksum="FB9FCE561B387FE6" modified="2018-01-31" version="1">MDNKSMLMIPGPTPVPEAALLAMAKHPMGHRSKEFDAIFAECTENLKWLHQTKSDVLSLTVSGTGAMEAGIINFLSAGDRVLVGTNGKFGERWAEVAEAYGLNVEIIKAEWGLPLDPENFREKLEADTEKQIKAVIITHSETSTGVLNDLETINRHVKAHGEALIMVDAVTSLGAANVPMDAWGIDVIASGSQKAYMIPPGLGFVAVGPKAWEAYKTAKLPRYYLDLGKYRKDAAKNTTPFTPSVNMFFGLQVTLQMMKAEGLENVFARHKRLMTTTRAAVQALGLPLLAADDAASPAITSVMPPAEVDAQKVRTLMKKRFDIALADGQDHLKGKIFRIGHLGFVCDRDILAAISSLEVVLREMGYEGFTPGAGVAAAAKILAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5C5</accession>
    <name>A0A2G4F5C5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56687">
        <property type="protein sequence ID" value="PHX56687"/>
        <property type="gene ID" value="CP500_004120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="206" mass="23752" checksum="FE37F57615591E05" modified="2018-01-31" version="1">MAFSNYKTIGATIKEFQITYTEANFIVETAFNVSDYFREDLQIMMTEGVVDNSEFAVCENLIYPVLKEVWKCYRSKFVLWSHEALNYDTKLSGFPEYILAKRSPLGKVVFDKPYLLIVEAKQDKFEEGWAQCIAEMIAAQRLNDELQVTILGIVSNGKTWQLGKLEGQIFTKNINPYTIYELDKLFGAVNYIFQQCESQLKQLVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5L6</accession>
    <name>A0A2G4F5L6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Copper chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57015">
        <property type="protein sequence ID" value="PHX57015"/>
        <property type="gene ID" value="CP500_002170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="6660" checksum="E9A500FEFDFB079F" modified="2018-01-31" version="1">MTLQLKVPKMACSACANTIAQAVKTLDPAAAVEADLKTKLVNIQTVKPESEVKFAIASAGYPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5M1</accession>
    <name>A0A2G4F5M1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ShlB/FhaC/HecB family hemolysin secretion/activation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_001910</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPS (TC 1.B.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57060">
        <property type="protein sequence ID" value="PHX57060"/>
        <property type="gene ID" value="CP500_001910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005565">
        <property type="entry name" value="Hemolysn_activator_HlyB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013686">
        <property type="entry name" value="Polypept-transport_assoc_ShlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08479">
        <property type="entry name" value="POTRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03865">
        <property type="entry name" value="ShlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013740678" evidence="8">
        <location>
            <begin position="20"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="9">
        <location>
            <begin position="114"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="43"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="607" mass="66702" checksum="E9CF88894AB392FB" modified="2018-01-31" version="1">MFPFAVSLLSIVSILPSYANQPTINENDSQCQNQLNCNFLAQNPQTPLGNIPPDLNRDRAQNPVLPPPPTQPDPNRDRFLQPVPQPSPEPPQAPPRVEPQPPSPVPPPMPAGEIQVQKIQVTGSTILSPDEIKALVNPLEGRLATLEQLKQVADKITEIYLNRGYITSRAILPPQTITAGVVQIQVIEGKLSKIEVEGTKRLHKAYISSRIRLGAGMPLSTAKLEDQLRLLRVDPLFNNVEARLRAGDNEGESILIVRVSEANPFQASFSIDNYSPPSVGSERLGVSLRHRNITGNGDELAAAYYRSIGDSDVFDFSYRIPLNAMNGTLQLRAAPNRNSIVQAPFDAFDISGKSNLFEVSYRQPLVRSPIEEFALSGGLTYQTGRTFVAGEPTPFGIGPDSNGVTTTSAIKLGQDYIRRDPQGAWALRSQFTIGTSLFEATSNEGSDPDGQFLSWLGQVQRVQRLNKKHLLIVQGDLQLSANSLLSSQQFVIGGGQSLRGYRQNVRSGDNGFRFSLEDRITLQRDASGIPKLLLAPFFDAGTVWNMSSNPNKLTNQTFLAGLGLGVIWEPIPRVNVRVEYALPLVRIRDRGDNLQDSGIYFNIIYTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5T2</accession>
    <name>A0A2G4F5T2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1636 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57108">
        <property type="protein sequence ID" value="PHX57108"/>
        <property type="gene ID" value="CP500_001510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012863">
        <property type="entry name" value="DUF1636"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07845">
        <property type="entry name" value="DUF1636"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="14632" checksum="319C9E81039F22A6" modified="2018-01-31" version="1">MNGINATVRTKHSLLVCTACASVWKNGQREGKSGGQQFLEDLSQLAKDWELSDEFDIQEVECMSACSHSCAVSFAAAGKYTYLFGDLPPNESESVEAVLECASQYYAKSDGLLPWSERPPALKKGVLAKIPPLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F645</accession>
    <name>A0A2G4F645_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000885</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57230">
        <property type="protein sequence ID" value="PHX57230"/>
        <property type="gene ID" value="CP500_000885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03130">
        <property type="entry name" value="HEAT_PBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="248" mass="27203" checksum="BCF7515446E04633" modified="2018-01-31" version="1">MHNNDNPIAINTDPELESPLDQLDESEPPLPDPDQMLPLLESPEAQHRMIAARAFCELQDDRAIGPLINLLRDVCPLVRVSAAYALGRNPSPDAVEPLIQQLNRDWNGYVRKGVVWALGNCRDHRALVPLIDALKTDISAVRLWAASSLGQMAKVGYYVVIAAIPPLIQALRRDAVSAVRSNSAWAIGQLARELPNNVVYAGAIDALIEALEEDEDMGVREDAKSSLLRVGDPRGLQIIEDLEMEGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6B1</accession>
    <name>A0A2G4F6B1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57231">
        <property type="protein sequence ID" value="PHX57231"/>
        <property type="gene ID" value="CP500_000890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="2">
        <location>
            <begin position="284"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="347" mass="39564" checksum="7799DC87C0976BD8" modified="2018-01-31" version="1">MNFINPKTDFGFKKIFASPQSKEVLMSFLNAMLYNGEPTIQDLEIIDPYAAPAITGLKDTYLDVKAKITGGITVIIEMQVINVEAFTKRVIYNAAKTYATQLKPREGYSKLVPLIALTITDFVLFENTEKFLSHFVFKEVEENFEYYREIELVFLELPKFHKRLEEVENLIQSWVYFIKNAPDLDQIPDKLASVPEIQTAFNIANRSSLNLDELQALEKREMFFEDQRGAVIKGIREGLQAGRQEGLQAGRQEGRQEGIQEGRQEGIQEGRQEGRQEGRQEGRQEGLIEGQTGLILRQIARRTGEISPEIQTRIQQLSPQQLDNLGEVLLDFTSQEDVIAWLESVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6F3</accession>
    <name>A0A2G4F6F3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57336">
        <property type="protein sequence ID" value="PHX57336"/>
        <property type="gene ID" value="CP500_000720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="92" mass="10091" checksum="3C959CBDD056C017" modified="2018-01-31" version="1">MVDVYCGTGVPPVLWKVLNRQDACSTIIMVDVYCGTGVPPVLWKVLNRQDACSTIIMVDVYCGAGVPPVLWKGFKKVRSPFMTKSAIAHFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6S8</accession>
    <name>A0A2G4F6S8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57207">
        <property type="protein sequence ID" value="PHX57207"/>
        <property type="gene ID" value="CP500_001430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="24"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="36318" checksum="B44406EF15ADF94A" modified="2018-01-31" version="1">MTQSLSPITSVRAFPDHTQLPESDGTFVKNFQEHPQCILLTDSLETTLQTLHPDGMYAIGQDSGIYWRETDPPERGAEAPDWFYVPNVPPLVDGEIRRSYVLWREYMVPLIAIELASGNGSEERDNTPLSRTSEGVTQKPGKFWVYEQIIRIPYYAIYIIKTGELEVYNWVNTRYIRLEPNDRGHYSIELMGVELGLWEGSYQNQTQRWLRWWDNQGNLLLIGSEQARLERLHTEQERQRAEAESQRAEAESQRAEAESQRAEAESQRAEAESQRAEAESQRAEAESQRADREQQQKERLAAYLRSQGIDPDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Z2</accession>
    <name>A0A2G4F6Z2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydroorotate dehydrogenase (quinone)</fullName>
            <ecNumber evidence="11">1.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DHOdehase</fullName>
            <shortName evidence="11">DHOD</shortName>
            <shortName evidence="11">DHODase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pyrD</name>
        <name evidence="13" type="ORF">CP500_000830</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(S)-dihydroorotate + a quinone = a quinol + orotate</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="11">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Cell membrane</location>
            <topology evidence="3 11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57357">
        <property type="protein sequence ID" value="PHX57357"/>
        <property type="gene ID" value="CP500_000830"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00225">
        <property type="entry name" value="DHO_dh_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="12">
        <location>
            <begin position="61"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="127"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="268"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="78"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="347"/>
            <end position="348"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX57357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="387" mass="42516" checksum="10467BE84F782F72" modified="2018-01-31" version="1">MDIYQFGLRPLLFSVLKADAEWVHNRSLQILELADRTQSNPATSRILDQFHQSFGLQDSRLEQSLWGLNFKNPVGLAAGFDKNGVAAGIWTKFGFGFAELGTVTWHPQPGNPQPRLFRLTQDSAALNRMGFNNQGSQAMAARFQAAQSRGKLDNSYPSPDSPFPLGINLGKSKVTPLEQASTDYLESFKLLQDWGDYFVVNVSSPNTPGLRSLQDAAQLSTILDILQQTNQGIKPILVKIAPDLEWEAIASILDLAKTYQLAGIIATNTTIRRDGLKTQTLRETGKPISEEAGGISGLPVQQRSTEVIRFIWQQTAGKLPIIGVGGIFTADDAWEKIAAGATLIQVYTGWVYEGPWMVRRILQGLLNKLEEKGFNSISEAIGSGNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUD9</accession>
    <name>A0A2G4EUD9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_022965</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000255">
        <property type="protein sequence ID" value="PHX53162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53162">
        <property type="protein sequence ID" value="PHX53162"/>
        <property type="gene ID" value="CP500_022965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="10"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="402" mass="42480" checksum="CE48E81A24622901" modified="2018-01-31" version="1">MIQLKEEFKALTAVCVVFFILGFVFGNWVSRIPDIKEALELSKSQLSIALLMIPLGGLCSMQIMSRIISVYGVGKATGIATLLYCGSILLPGWAPSYPLLIIATLFFGAGFGIVDVGMNANANVVELRHNTLIMSRCHALFSLGSMMGGAIGSVVESLVIDPSWHFTIVGLVSGVGSLVIIGWLIEGKAEVDSDEDEQTEQTNSLVLPSQVLLGLGILFLCVMFSEGAIADWSAIYFREDLGVSPGLDTFGFVMFYSAHVAGRLLGDWIVESFGSRNVALVGCSLAATGISMTLFTGYYQVAILGLTCMGLGLSSLGPIVFRVAGSMLDGNSEKNIAFVATIGYVGFLSGPPLIGFAAGVVGLHNALFIICLCCLLSVLLTYTIPTEKTTVTINPAEPPASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUE5</accession>
    <name>A0A2G4EUE5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_023020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000259">
        <property type="protein sequence ID" value="PHX53155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53155">
        <property type="protein sequence ID" value="PHX53155"/>
        <property type="gene ID" value="CP500_023020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="728" mass="72328" checksum="D441EB9176BF8612" modified="2018-01-31" version="1">MLNATSAGGSIIADDSGIDSLTLNGVTLAIGLAAGTAGVTRGGEFNTDLLIDLNKDGVFKAADDLLIVDFFAEPNLEEGDGFIEQVGNLSGAAILKSFPLKATPGPDFLPGGSGDDNIDGLAGNDTIEGNQGNDSLFGNAGNDVLNGDELITISEAGGTVILGTGIGNDYLDGGDGNDTLDGGEGNDTLDGGAGDDSLKAGKGNDIINGGEGKDSLYGNEGNDSLFGGAGNDILFGNVGNDTLDGGDGDDSLVGGLGNDSIVGGAGIDTVSYGTLPSPVNINLAAGSSTAEGTDTLTGIEVIIGTTFADTIIGSSSDETLIGNGGADILTGGGGNDTFVLDPATAGGSKIQGAAGTDNLVLADTTLVTSLTNGSVGIGRSGTSLVVDLNKDGQVNLANDIEILNFFASTTGNVPGTGFIENVAGTPGNTILAKFAIPIPIPIPIPTPTPTPTPTPRGPQILTPTIPISSPNTTVDSTLNGGTLNDFLFGTAQADSLNGLAGNDTIYGLDGADNIGGGDGEDSLFGNAGNDFIDAGNGNDVVYSGKGDDGILGSAGNDSLYGNDASDIVFGGDDNDVIFGGKGDDSLSGDAGDDSVFGQLGNDYLLGGSGNDVVNGGEGDDTLTGIDPIATNPGFGEFDTLTGGEGKDRFLLGDSDKVYYSGDGNAVISDFNSVEDAIVLSGVKASYSLSVSGNVTSLFLKKAGQSDNLIATVQGVTDLNLDRPYFTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUE9</accession>
    <name>A0A2G4EUE9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000256">
        <property type="protein sequence ID" value="PHX53161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53161">
        <property type="protein sequence ID" value="PHX53161"/>
        <property type="gene ID" value="CP500_022990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="62"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="327" mass="36609" checksum="6F8911A4E5F22743" modified="2018-01-31" version="1">MTNSLHWHQRIGTQRDWVWRGWQTRYTYFRPSRSQESRNQGSIANQDSTTPEIDSQPPTTPIILLHGFGASIGHWRQNMAALSEFHTVYALDLLGFGASQKAPVDYDVSIWVDQVYDFWLTFVRKPVVLAGNSIGSLICLAAAAAHPDMVAGIVMISLPDPSVRAEAVPGWLLPAIETVESIFVSPLILRPLFYFARRPSFVRRWVAFAYSGPEAITDELVEILAGPAGDRGSARAFCALFKAVGSSQFGPSVKTVLRELTIPMLLIWGRQDRMIPPRFAKPHQFVECSPNYVKLVELDNAGHCPQDECPEQVNQEILDWMSSANLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUG0</accession>
    <name>A0A2G4EUG0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_023170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000271">
        <property type="protein sequence ID" value="PHX53128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53128">
        <property type="protein sequence ID" value="PHX53128"/>
        <property type="gene ID" value="CP500_023170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="209" mass="22452" checksum="73BA0952A42E794D" modified="2018-01-31" version="1">MHTPKCSPSSVAHPAPAGSKTNGRWILTLGTQLATLGLLATALPPTPASAITIRFPRPKNEYRACSVELMGAGLSADAAASACASALHPRDISKCVVQINRKTNIVAAEALASCERVRRPKDLATCVVDINTKSRTQTTTPLLVLDQCRRSLLPEQFSECVVGLSRQVDFSIDRLMTTCLDTRDKVSQLDDRPTPTLPVDLIPPPSKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUP5</accession>
    <name>A0A2G4EUP5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000248">
        <property type="protein sequence ID" value="PHX53186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53186">
        <property type="protein sequence ID" value="PHX53186"/>
        <property type="gene ID" value="CP500_022830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="13261" checksum="8368A2446E416C6B" modified="2018-01-31" version="1">MARYTGFFIVAVPLDRLRHSLIEILESCNLDIIYDTGDSVMARELPGQVSVPKRVIAEVLIDQNMSSESEVRINFVLKNDELPLKTNNHCRQMFELVSHSIMNNRNWRLLESMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV37</accession>
    <name>A0A2G4EV37_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_022075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000213">
        <property type="protein sequence ID" value="PHX53326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53326">
        <property type="protein sequence ID" value="PHX53326"/>
        <property type="gene ID" value="CP500_022075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="23"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="98"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="151"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="226"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="440"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="514"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="565"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="643"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="736"/>
            <end position="992"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="995" mass="112546" checksum="B3A1D73F06B1884E" modified="2018-01-31" version="1">MRDQKMEHKAMDCLNMKEALQQMEAKYYSIFENAISGIFQTTPEGRYLSANPALARIYGYNSTDEMMLALTDISHQLYVETQRRSDFIAALQEHDIVSDFESQIYRRDGTIIWIAENARAVRDQNGELLYYEGFVEDITQRKQAESGLRESEERLRLVIESVKDYAIFMLDIDGYVASWNSGAEGIFGYKSYEVVGKHSECFYTKEGLELSKPKEKLAIAIAEGRYHDEGLRIRKDGSQFWTKVIVTPLRDESGELRGFSQVMQDITKQKRAEEERMQLITSLQESEKKFRTLYESTTDAVMLLDEIGFLDCNSATLKLFGCNTESEFCGKHPSEFSPQMQPNGQDSSSLSQERINVALTAGSCRFDWIHCRLDGSEFPAEVLLTCMDIGGKIGLQAVVRDITERVQAEEALKHANEVLECRVKERTSELESAIKQLRWSEEKFSKAFRSSPDPMTITTFADGRLIEVNDSFLSMIGYSLEEALLYTVPQLNIWVKPEERVKFRSILQEKGVVRNHEYEFRVKSGAVVVCLLSAELIDLDGELCMLAVMTDITDRKHAEEALRESQRALATLMSNLPGMAYRFRNDTDRSMEFVSEGCYELAGYSPEEFTGTRQISLSELTHPDDRDTFCNAVEVALRENRPYQLTYRITSKSGEVKWVWEQGLGVFSESGELIALEGLITDISEQKRSEEALVRSQTELTQQKLQLENTLHELQQTQAVLIHTEKMSTLGQMVAGVAHEINNPVSSVCGNLVHLSHYTDDLLDLLALYQKNFLQPPAVIQDKIEEIELDFMLEDLPKAMSSMRVGADRIREIVRSLQIFSRKDDNKMSLVNLHEGIDGTLLILQSRLRAKGSYPEISVIKEYGNLPLVECYAGKVNQVFMNLIGNAIDAIEEYNQGRSLVEVKANRSKIKIKTELQNSNAIVRISDNGPGMPEEVSQQLFDAFFTTKPAGKGTGLGLSISYKVVKEHGGKLSCVSAPGQGAEFIIELPIEQISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV56</accession>
    <name>A0A2G4EV56_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000200">
        <property type="protein sequence ID" value="PHX53423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53423">
        <property type="protein sequence ID" value="PHX53423"/>
        <property type="gene ID" value="CP500_021590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013908582" evidence="1">
        <location>
            <begin position="26"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="17907" checksum="4CE74D2C86676BA7" modified="2018-01-31" version="1">MYFLPKQIAALILIVAACCFLTVSCTDNSRAAQCIRLNDAVTKAYSFLGKERDSNDTATIKKLAKDLNQTSKELESLQLTDTNLKEFQSESVKSFRQMGQTFGDIGKSLEVGNSAPISIEGREQIRKARADIIKYGEQANDAVVNQEAVTKKLIKYCQSDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVC8</accession>
    <name>A0A2G4EVC8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1997 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000190">
        <property type="protein sequence ID" value="PHX53493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53493">
        <property type="protein sequence ID" value="PHX53493"/>
        <property type="gene ID" value="CP500_021235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018971">
        <property type="entry name" value="DUF1997"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09366">
        <property type="entry name" value="DUF1997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="22372" checksum="DB7BED453C755F6F" modified="2018-01-31" version="1">MFTRFNACQSVEIVVPEERVAIQHYLRQPRRLVNALVDQSRTEQLSDDCFRLKMRPLEFMMMSIQPTVDMRVWALSDGTINLESVACEIIGVGYINDRFALKLKGQLSPHQIRGVTHLQGKADLEVRVELPPPLWLTPKPILEATGNGLLKSVLLSVKQRLMYKLLLDYRRWAGNETNETELMLTDRPKILSIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVF1</accession>
    <name>A0A2G4EVF1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000186">
        <property type="protein sequence ID" value="PHX53511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53511">
        <property type="protein sequence ID" value="PHX53511"/>
        <property type="gene ID" value="CP500_021120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="22"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="112"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="166" mass="18587" checksum="58E8681904294E22" modified="2018-01-31" version="1">MIDREKQLNKTPIMSKTVADLMTREPLTARVEMSVKEAIKILADRRISGLPVVDHNDLLIGIISESDLMWQETGATPPTYIMVLDSVIYLENPSRYEQELHKALGQTVGEVMSRDPVSITPEKSVREAAKLLHERHIHRLPVLDTAGKVIGILTRGDIVRAMVAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVJ1</accession>
    <name>A0A2G4EVJ1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_020830</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000177">
        <property type="protein sequence ID" value="PHX53562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53562">
        <property type="protein sequence ID" value="PHX53562"/>
        <property type="gene ID" value="CP500_020830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="602"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="636"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="5">
        <location>
            <begin position="762"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="687"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="95"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="986" mass="113342" checksum="AE8DC2C4ED2BE578" modified="2018-01-31" version="1">MNTKMTKALLGNEGWGVKAGKLIKAAFLPTVYHADRIGETQARNTDLTLQTNKEIESSLQEIRNKELVLQGFQRQANLEFKPEEGDLSHSLQSELARLNREFQAQEGLLNRQMQEQLTKINREFQAKEGKLNCEHQIQLEIFRAEIQKWCVEQQKELQLQLKSLDAQLARELRIYDRKTAIEAIQEQKRQGNSPIWLIAEDIVKSNPAQNPIPLRVFLSPPTLQFDRSGDGNDAAKDFPEMEKTLGIYLQQFFERYLAQGRPVEFLSGAWTSKLFHSQAATQSMFRGLKTEPTLILESAAEGDIFNLSFGYWGLNWATYRYKSPIPMLPWREVLFDFAKDRVLQWQAQRIAYIAEGNSVEEFDELYGTEAVNSFWHNLKIIEKERKCEAIGTDPSEIPRPYSIHKKDYQRFQQFIGICHCLIAGLLADEYFFLHVSPEVRQRPLLPQLLPDLLQDIPSEEQEQLVEIAMNFYEMLYNVIAESESAWIPELKLDLAEGLLDLPDRRWATAQIFESVKAWLKLRDLSVPSGNQEILDALDAALTIDDLKYVEKLNSCFAAVGESHQLSVIESCYKRAIGRCQEEKYAAAIVDFNQVLQLNANFAKANFNRGFAYAKLEQYRAAIEDYTQVLRLEPNHADAWNNRGNACYKLGAYESAISDYTQALNLNPNLPGVLHNRDVAQGVWDEKKRQQRLEEEEQQHHSEQERQQRLEEEKRQRAAEEEAKIKEFHFEIITVDNRGQEVSRKPGKASQKVENLGNWVNLEMVYIPGDTFQMGSSESNSEQPLHQVTIKPFYLGKYPITQEQWEAVMGNNPSEFKGAKRPVEQVSWDDAVKFCQKLSQKTGKTYRLPTEAEWEYACRAGTTTLFHFGETITPDLVNYDGNYPYDSAQSGLYRQQTTDVGSFPPNPFGLYDMHGNVWEWCSDRWHDNYNGAPTDGSSWETGTDDRRVLRGGSWLNVAFLCHSALRSRVSAGLRSSFFDFRVALVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVN3</accession>
    <name>A0A2G4EVN3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000181">
        <property type="protein sequence ID" value="PHX53538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53538">
        <property type="protein sequence ID" value="PHX53538"/>
        <property type="gene ID" value="CP500_020950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="38"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="27697" checksum="8EAA4DD2CAC9AD38" modified="2018-01-31" version="1">MVLQISSSSKAPIVTWEALPADFVLPDDPVENIQQPPLAAALTDALGAAGRIGPALIGSNFGLVATVNKQTVVKAPDWFYVPQVHRVAEGAIRRSYTPNLEGAPVSVVMEFLSAEDYGELSVRSTPPYGKLYFYEQILQVPTYVTYDPYDPKLEVRYLQNGSYETQTADAEGRVRIPELDLWLGIWPGERLGQTINWLRWWDEAGNLLLWSSEQAQQERLRAEQERLRADVLAAKLRELGVDPDRLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW17</accession>
    <name>A0A2G4EW17_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)H-quinone oxidoreductase chain 4</fullName>
            <ecNumber evidence="7">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(P)H dehydrogenase I, chain 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">NDH-1, chain 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ndhD</name>
        <name evidence="9" type="ORF">CP500_020370</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cellular thylakoid membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000167">
        <property type="protein sequence ID" value="PHX53650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53650">
        <property type="protein sequence ID" value="PHX53650"/>
        <property type="gene ID" value="CP500_020370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00491">
        <property type="entry name" value="NDH1_NuoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022997">
        <property type="entry name" value="NADH_Q_OxRdtase_chain4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="3 7" id="KW-0874">Quinone</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="8">
        <location>
            <begin position="134"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="528" mass="57973" checksum="FAB3BA406C230BE4" modified="2018-01-31" version="1">MDTANFPWLTTTILFPIAAALLIPLIPDKDGKTVRWYTLIVGLIDFALLVYAFYTQYDFSNPGLQLVESYTWVEQLDLNWSVGADGLSMPLILLTGFITTLATLAAWPVTFKPKLFYFLMLVMYGGQIAVFAVQDMLLFFLVWELELVPIYLILSIWGGKKRLYAATKFILYTAGGSLFILLGALTMAFYGDTVTFDMRAIAAKDYSTNIELLLYAGFLIAYGVKLPIFPLHTWLPDAHGEATAPAHMLLAGILLKMGGYALLRMNAGMLPDAHATFAPLLVILGVVNIVYAALTSFAQRNLKRKIAYSSISHMGFVLIGIASFTDLGMSGAMLQMVSHGLIGASLFFMVGCTYDRTHTLMLDEMGGVGQKMRKVFAMWTTCSMASLALPGMSGFVAELMVFVGFATSDAYNPVFKVCVIILAAFGVILTPIYLLSMLREIFYGSENKQLVEHEELVDAEPREVFIIAALLVPIIGIGLYPKMLTQVYDATTVQLTARLRDSVPSLVAKAAADKTVSLRAPAIELSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWC6</accession>
    <name>A0A2G4EWC6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CinA-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CinA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53766">
        <property type="protein sequence ID" value="PHX53766"/>
        <property type="gene ID" value="CP500_019645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00226_B">
        <property type="entry name" value="CinA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041424">
        <property type="entry name" value="CinA_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008135">
        <property type="entry name" value="Competence-induced_CinA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18146">
        <property type="entry name" value="CinA_KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006728">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00200">
        <property type="entry name" value="cinA_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="2">
        <location>
            <begin position="4"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="421" mass="45355" checksum="DDB2AD629394F8A2" modified="2018-01-31" version="1">MVAEIICVGTELLLGDILNSNSQFLAKELASLGIPHYYQTVVGDNPDRIKQVLEIAVGRSQLLLFTGGLGPTPDDLTVETIADFFGVPLIERPEIIADIEQKFAQRGRTMSKSNRKQALIPEGAEILPNRTGSAPGIIWQPVPNVTVMTFPGVPAEMHLMWRETAVSYLQNNGWCSGTIYSRTLKFWGIAESALAEKVEGFLNLTNPTVAPYANHGEVKLRISAHAESEAVAKNLISPIEQQLRQIAGLDCYGADTDTLASTVGQLLLDRGENLSVAESCTGGGLGAMLTSIAGSSGYFWGGVISYDDRVKEKLLNVKPEDLTEFGAVSHQVAQQMAAGVRASLNTSWGLSITGIAGPGGGTDSKPVGLVYVGLAGPNDEIESFEYHFGDARTRDWIRNLSACTALDRLRRKILLAKVEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWC7</accession>
    <name>A0A2G4EWC7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000151">
        <property type="protein sequence ID" value="PHX53829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53829">
        <property type="protein sequence ID" value="PHX53829"/>
        <property type="gene ID" value="CP500_019410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="258" mass="29036" checksum="131FD1EC6ACFCC92" modified="2018-01-31" version="1">MCQLLGMNCNVPTDICFSFEGFSARGGKTDVHQDGWGIAFFEGLGCRIFIDSKPAVDSPIAELVRRYPIHSTNVIAHIRKATQGEIALENCHPFIRALWGRYWVFAHNGNLENFHPESAGFYQAVGNTDSEKAFCLILEKLRESFPQHKPALTELYAVLNEITKTLAEYGILNFLLSDGEHLFVHCSTNLHYIVRQAPFASAHSIDEDITVDFRELTKEGDRVAVIATFPLTDNEVWTQIQVGELLVFQEGLPINFEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWH3</accession>
    <name>A0A2G4EWH3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000146">
        <property type="protein sequence ID" value="PHX53871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53871">
        <property type="protein sequence ID" value="PHX53871"/>
        <property type="gene ID" value="CP500_019170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="8957" checksum="FC54AB83B96D285B" modified="2018-01-31" version="1">MFVGIQIIQFRAGRMPTPQEQFSLCGTGILPVHGEWYTAVSLTGLGDRAKIHQFSTQPQRVLNLLCKRMETKHDQNNCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWN0</accession>
    <name>A0A2G4EWN0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PhzF family phenazine biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000139">
        <property type="protein sequence ID" value="PHX53931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53931">
        <property type="protein sequence ID" value="PHX53931"/>
        <property type="gene ID" value="CP500_018805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="294" mass="32701" checksum="18E56CA04C8EF9CB" modified="2018-01-31" version="1">MNFYIVDVFAESKYAGNQLAVFCGAGVAELSETQMLMIAREINYSETTFIPSNQPQNGGYDVRIFTPKKELPFAGHPTLGTAFVLQQEIIKKLVEQVILNLEVGQIPVTFNYHNEAADILWMRQNQPKFGQVLSAESLANVLNLEVDEIDARFPIQEVSTGVPFIIVPLKTLPSLKKAQVNLDKYFELIETTEAKEILIFCPETYNDINDLSVRVFAHSLGIPEDPATGSANGCLAGYLVEYAYYGAEKIDVRVEQGYEINRPSLLLLQSQRKDGEIEVLVGGKVVMVAKGEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWQ1</accession>
    <name>A0A2G4EWQ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53982">
        <property type="protein sequence ID" value="PHX53982"/>
        <property type="gene ID" value="CP500_018580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="20178" checksum="B065075D88892A06" modified="2018-01-31" version="1">MTESNKPIGQQFSNVMPVWKFCFLMIITFGLYELPWCHKQWKFLKDRENLNINPWVRAVFFLFTMHNLAKKVFVLAEKQGYRERPSAFQVTLIYWIFFILSFLPDPFWLISFFGVVPLLTILKAVNYYWEQEQPNLPVRKSFTGREVAWIVFGAILWLLVIIGSLLEEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX57</accession>
    <name>A0A2G4EX57_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Germane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_018325</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54030">
        <property type="protein sequence ID" value="PHX54030"/>
        <property type="gene ID" value="CP500_018325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019606">
        <property type="entry name" value="GerMN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10646">
        <property type="entry name" value="Germane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00909">
        <property type="entry name" value="Germane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Germane" evidence="3">
        <location>
            <begin position="158"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="27855" checksum="5E9E5F0CFDA7EFE7" modified="2018-01-31" version="1">MKDGQETRRVPTVVIASICGLALLTGGSIAWWSSSRSSTSAVMQSTAPTTAPTTAPIQSPTPGESPAAIIPVPAPSPVEIPQAQTPQAQTPQARTPKAQTPQALSPQALKSPSSQPQPAQPTATQTVQVYWVKDVGGKFQGVPTRVALKEVDRPDTTLQAAFNSLLAGPKDAKVYSEIPKGTKLRSLSVKNEGVYVDLSGEFVSGGGSSSMSSRLGQVIYTATSLKPNAKVWISVEGKPLELLGGEGLEVAQPSTRQTFDKNFPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXA5</accession>
    <name>A0A2G4EXA5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000124">
        <property type="protein sequence ID" value="PHX54106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54106">
        <property type="protein sequence ID" value="PHX54106"/>
        <property type="gene ID" value="CP500_017860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="5"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="230" mass="26948" checksum="3341B298B6D3D7D8" modified="2018-01-31" version="1">MVTQLQSPDKSKIIYPDDNGEPMSNNTEQFRLIVWIKENLELLFGDDPNVFVAGDLLWYPMEGNNNIRQAPDVMVVFGVPKGYRGSYQQWLENDIAPQVVFEIWSEESICILTKRFQFCDRYGVEEYYFYNPQTLELGGWLRIEGEFEVIEQMDGWVSPRLGVRFQLSETELEMFRPSGEAFMSFGELDRLRQKAEVRTQQAEMMLEQERSRSQALESKLREMGIDPNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXB3</accession>
    <name>A0A2G4EXB3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1257 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000119">
        <property type="protein sequence ID" value="PHX54169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54169">
        <property type="protein sequence ID" value="PHX54169"/>
        <property type="gene ID" value="CP500_017605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009666">
        <property type="entry name" value="Uncharacterised_Ycf35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39638">
        <property type="entry name" value="PTHR39638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06868">
        <property type="entry name" value="DUF1257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="117" mass="12975" checksum="4537077CB0C7F881" modified="2018-01-31" version="1">MSHFSTLRTKITDAEILKASLRDLGISVKSEADVRGYNGQRVRSDIVATLEGEYDLGWSRNSDGSFDLIADLWGVAKKHNQTELINSINQKYAVNKTLAAVKQRGLQNANVKLVVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXL6</accession>
    <name>A0A2G4EXL6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Toxin-antitoxin system HicB family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54218">
        <property type="protein sequence ID" value="PHX54218"/>
        <property type="gene ID" value="CP500_017275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9166" checksum="47AA64DD38F89C56" modified="2018-01-31" version="1">MSTLNVNIPDSIYKSMQELAQQDNISVDQFIAAAIAEKISVLMNESYLQERANRGSREKYESVLAKVPDIEPEDYDKLTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXR0</accession>
    <name>A0A2G4EXR0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ANAPC4_WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54325">
        <property type="protein sequence ID" value="PHX54325"/>
        <property type="gene ID" value="CP500_016760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037783">
        <property type="entry name" value="Taf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="PTHR19879"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1049"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1089"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1132"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1174"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1221"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1262"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1303"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1344"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1385"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1425"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1525"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="domain" description="ANAPC4_WD40" evidence="4">
        <location>
            <begin position="1536"/>
            <end position="1621"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1568"/>
            <end position="1608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1689" mass="189589" checksum="0B758C195A1A8506" modified="2018-01-31" version="1">MINSHYHPDTPAQQNQSSLQTLSRTLKMSQGQFSLTLVRCNYGVLREQIVGKLHEDCAVDIRELSLPTSVKTLYTTIEAELAGSQPQALMVFGLESVNAIDRVLTSTNYVREEFRNNFPFPVVLWVTDKILKKLIRLVTDIESWTTTVEFVLSPDELVDFLGKSADRIFSGILESGNWYLTNSAILGAGSLTELESARKDLQTCNIHLEPAIEASLQFINGRHEYACQNIPTAIESYQKSLNFWKYQVAFLGYQTEFSKLLFTVHPAPVLEGILLFHIGLCYRFQGEQHRTGNRPYWTEAKNYFQQCIDVLETAGQQANVGKFINQLGEILQYLEDWDALWKLAIKARRLHQNMENSTVHLAQDYGFLAKVALEQQKWQGAKEWALVALDVLNSNLEVSGHGTPVKSQHHGLYLLILAEAEKELGELPKAIAHLEIARSETAPCYNPQLYLRVLELLRSVYFQRGEYLQAFQVKQDYRSIEHTYRFRAFIGAGKLQPHRQAINPATETIAVNATIADEITASGREQDLNRLIGRMNSAQNKLTVIYGQSGVGKSSIVTGGLVPALKQKKIESRTVVPVLLQVYNNWPRELTRQLSGSKAEIFDRAMAEDFLDSAEVESEFAASEINDTFMPVLHEEFTDNDEKIVPEQPVELVVKKQTIEYDKIIKELQINSEHLVTVLIFDQFEEFFFVWKEQAEREIFFEFLRECLNIKYLKVILSLREDYLHYLLEFCRPKNNREFIKNDILGDILSKDILFYLGNFSIADARSIIHALTERSQFHLEPELIEELVKDLAGELGEVRPIELQVVGSQLQQDDITTLTQYQELGNNPKQKLVAKFLEEVIQDCGPENEGAVRRVLYLLTDEDDIRPLKSRAELALDLATFEEADKLDLVLELLVKSGLIFRWTELPVELYQLVHDYLVSFIRQQQESDTKAEFEELRKQHKINRKWQRNLASLGLVGFASLSGLALYQTKLGDEARQQAEKARTDALDSGSQALVLSNEKDQVGILATSIKIATDSLKSTALPIDTKNQIAERLRRAVSGVQEYNRFEQHSNFVLDVSVSPDGNRVASASADKTVKLWSKEGKLLNTFNHSDIVTSVSFSPDGKTIATACADRQIRIWRVDNNKSAIATLEGHKDIVTSVSFSPDGKTIASASYDKTIKIWNVASKKLLQTLTGHQDLVLGARFSPDGETIASASADKTIKLWNRLDKSEKFQTIPKTLNKHSDIVYSVNFSPNGKEFVSASADTTIKIWNREGKEIRTLKGHNEKVVSASFSRDGDKIVSGSADNTVKVWSRTGTLLNTFRGHQDDVRAVTFSPDGTIASASQDKMIKIWKPNNTPLNQILAGHGDLVTKVSLSSDGKIIASASIDQTVKLWQANGSLLRTLVGHTDSVNWVSIAPDNRTIASASNDQTVKVWSLDGKLLDTLKHGDIVNSVSFSPDGKIIATGSDDNKLYLWRWQDGQATLLTKVDHINQVVRVSFSPDGRTIATLTNDKPEPNKNDSKVVEKKKVYLWQINGSSAKLLTTLDHEKSVKDVTFSPEGKTIATASADKTVKLWRFDGIKAALVEEHKHNDTVESVSFSPDGKLMAASAGNTVKLWNFAGGKATLSKTLESSYRMFSVTFSSDSKTLAFAIDRNVVLWPVENLELNKIVARTCDWLGDYLQNDSNVSEGDRMLCVGFGKQTLNKGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXZ7</accession>
    <name>A0A2G4EXZ7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000130">
        <property type="protein sequence ID" value="PHX54037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54037">
        <property type="protein sequence ID" value="PHX54037"/>
        <property type="gene ID" value="CP500_018240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="4"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="120" mass="13513" checksum="69A1B0BAD699A414" modified="2018-01-31" version="1">MALKYLIDENVTPIYATQLRRKRPDLVVWSVGDIGTPPKSTLDPEILIWCEDNGFILVTNNRKSMPVHLADNMAEGRHIPGIFVLNSDLSIGQNIEELILIADGSFDDEYQDQIVHLPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY26</accession>
    <name>A0A2G4EY26_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54432">
        <property type="protein sequence ID" value="PHX54432"/>
        <property type="gene ID" value="CP500_016155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013828113" evidence="2">
        <location>
            <begin position="30"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="166" mass="18282" checksum="65621F5B4F48ECF7" modified="2018-01-31" version="1">MNKVYPEPRSSRFMALLLTTLLTFPFVTACGSSQQGSAPPPPVDDTRAGAPANRPASPRPQAKQGLSNTQKVAITLVGAAALYYIYNQHKNKQEQGPQGQYYLSKNGRVYYRDAQKRAHWVTPPPEGIKVPESEASRYREFQGYNNQTTGKDLTSLPEAKTAVPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY32</accession>
    <name>A0A2G4EY32_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4327 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54443">
        <property type="protein sequence ID" value="PHX54443"/>
        <property type="gene ID" value="CP500_016050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025477">
        <property type="entry name" value="DUF4327"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14217">
        <property type="entry name" value="DUF4327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8504" checksum="C5742B0DD5878E95" modified="2018-01-31" version="1">MSQQVIQPMVKFQRQVQSLVTSDIIKPTDSIWKIALLYGDEWPYWKQQLLEFDFSMQDPVGELLAVEGWDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY42</accession>
    <name>A0A2G4EY42_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Photosystem I reaction center subunit IX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">psaJ</name>
        <name evidence="10" type="ORF">CP500_016310</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">May help in the organization of the PsaE and PsaF subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cellular thylakoid membrane</location>
            <topology evidence="2 8">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PsaJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54406">
        <property type="protein sequence ID" value="PHX54406"/>
        <property type="gene ID" value="CP500_016310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00522">
        <property type="entry name" value="PSI_PsaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002615">
        <property type="entry name" value="PSI_PsaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036062">
        <property type="entry name" value="PSI_PsaJ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36082">
        <property type="entry name" value="PTHR36082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01701">
        <property type="entry name" value="PSI_PsaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81544">
        <property type="entry name" value="SSF81544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="42" mass="4902" checksum="2319233C923234FA" modified="2018-01-31" version="1">MQYFLKYLSTAPVLAAAWMVVTAGILIEFNRFFPDLLFHPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY53</accession>
    <name>A0A2G4EY53_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000125">
        <property type="protein sequence ID" value="PHX54097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54097">
        <property type="protein sequence ID" value="PHX54097"/>
        <property type="gene ID" value="CP500_017915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="6600" checksum="0AD1840C7B578232" modified="2018-01-31" version="1">MPLISVENLVKSVENLQLACGNSVECFGKSRGKNKNCEGASGIGSPLSPSPPRAVSFSVYGVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY65</accession>
    <name>A0A2G4EY65_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Potassium-transporting ATPase subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_026787033.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000103.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54400">
        <property type="protein sequence ID" value="PHX54400"/>
        <property type="gene ID" value="CP500_016280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="13314" checksum="EC06D317C5982785" modified="2018-01-31" version="1">MVNYIPERGHFIRLNFDPQAGHEQMGTRPALVVSQTKFNQKMGFVFVCPISTTQRKNPFYVPIPEGELVTGVIMTDQLRSLDYRSRQASLIGECPEDLVREVLKRIEPILFENMTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY74</accession>
    <name>A0A2G4EY74_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000097">
        <property type="protein sequence ID" value="PHX54483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54483">
        <property type="protein sequence ID" value="PHX54483"/>
        <property type="gene ID" value="CP500_015830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="13597" checksum="F83DEB7F2146B759" modified="2018-01-31" version="1">MSTVMVVDDSVTLRQMITDLLKSRGLSVTVASDGVEALEEIKKNRPDLVVLDIVMPRMNGYEVCRRLKSDPKTQNLPVVMCSSKSEEFDRYWGIKQGADAYIAKPFHPQELVGTIKQLLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYC1</accession>
    <name>A0A2G4EYC1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_015750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54519">
        <property type="protein sequence ID" value="PHX54519"/>
        <property type="gene ID" value="CP500_015750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="256"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="55"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="300" mass="33055" checksum="2D39E517C6039FB1" modified="2018-01-31" version="1">MSTQIILVEPRLAVASPKPKQTKPGGLPSDQLLMGASGLLLLLLVGLAMFSKLKMDGLNKKLNFEEFRNRELQKKYKMALETMSKMEKNPDLIHSRDFNLDYLRMRMAEEVFHFAIVNQIKVKVKDKISIALRPTQGGVGDNSGNAGSGRQVDSMFDIEYETGDPTVKIEKRVLFRIQIKLMKLPTQATSATINQIIDCLETYLSPSDDHDSWQPTIQGRIVHIEWDQKAKPTPMLVLEQSNEGVNVTFRTTRAAGGVPANANDSQLAAGKGAKGAAKSPSKTASKSSSKTGTNRPSSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYD8</accession>
    <name>A0A2G4EYD8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ANAPC4_WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_015600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54544">
        <property type="protein sequence ID" value="PHX54544"/>
        <property type="gene ID" value="CP500_015600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037783">
        <property type="entry name" value="Taf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="PTHR19879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="597"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="638"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="ANAPC4_WD40" evidence="4">
        <location>
            <begin position="649"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="679"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="725"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="816"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="909" mass="100741" checksum="7AFA641186782977" modified="2018-01-31" version="1">MNFTTKPSYYQVGGSLTNNAPNYVKRQADDDLYNGLKAGEFCYVLNSRQMGKSSLQVRTIQRLRSDGIACAAIDISEIGNRGVTPEQWYAGLLRILENNFNLSDVVNVRTWWRDRNFLAPVQRLSEFIETVLLANISSNIVIFIDEIDSILALDFPADDFLALIRSCYNKRANNSEFDRLTWALLGVASPTDLCRDKNASSNTPFNIGKAIELTGFDETEAQPLAAGLVELTDSSQEVLREVLYWTGGQPFLTQKLCKLLLENAELISDLPQGGHGGTAPTFGEKDKINTAKEWVEKVVRLKIVDNWESQDVPEHLSTIRDRLFKQNQRIIRRLGLYQQILEQVEIVPDGSPEQMELRLSGLIIKHKDKLTLSNSIYQAIFNKVLIEKELDKLSPYSESIKAWLNSDCQDESQLLGGNDLQSALDWAAGKSLRNQDFQFLTASQKLILSNQNQLLCSATIETKKAQLEAGSAKQKAKQWIGIGSAILAASLVGAIGFSTLAYQRFKLAQASIKIEQTASDALLLAVSQKTENSQALSEALLKAIASGNNLTTLVKNKPELEKYPATIPLLALQVILDKISGQQQGKKTSILQKKMTWQAHTGAVTSVSFSPNQRFLATTGIDDRIRIWNLSGKKIAEWKALQQSVNIVNFSPNGDFLATAGKDSTVKFWNLSGKNISEFSAIQGSVSSISFSPDQNLLAVAGINNSVAIWQISQLPKIKSSPVELTGHNGLIRSVNFSPRGNFLITLDGKSTVRIWSLSGKLIKKLPIQAIGISFSLNQEQQRFATVTLNGKVGLWNLSKQELVSEFQTLHLDAKSISFSPDGERLATVGIDKTVRLWNLAGRQVAQFEFPENVVSVSWSRDGRQIAVAGSNGTVWLRQVESLEELLKQSCNYFTNQPEYLTRVATLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYN1</accession>
    <name>A0A2G4EYN1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Circadian clock protein KaiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">kaiB</name>
        <name evidence="4" type="ORF">CP500_015005</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer. Component of the KaiABC complex, at least composed of a KaiC homohexamer, a KaiB dimer and two KaiA dimers. The KaiABC complex also interacts with SasA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KaiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54631">
        <property type="protein sequence ID" value="PHX54631"/>
        <property type="gene ID" value="CP500_015005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042326">
        <property type="term" value="P:negative regulation of phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02978">
        <property type="entry name" value="KaiB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01835">
        <property type="entry name" value="KaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013474">
        <property type="entry name" value="Circ_KaiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039022">
        <property type="entry name" value="KaiB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011649">
        <property type="entry name" value="KaiB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41709">
        <property type="entry name" value="PTHR41709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07689">
        <property type="entry name" value="KaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01248">
        <property type="entry name" value="KaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02654">
        <property type="entry name" value="circ_KaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0090">Biological rhythms</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KaiB" evidence="3">
        <location>
            <begin position="11"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="104" mass="11748" checksum="B934D16D811ECBD4" modified="2018-01-31" version="1">MSPLKKTYILKLYVAGNTPNSVRALKTLKDILEQEFQGVYALKVIDVLKNPQLAEEDKILATPTLAKILPPPVRKIIGDLSDREKVLIGLDLLYEELREEDMNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYR5</accession>
    <name>A0A2G4EYR5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54662">
        <property type="protein sequence ID" value="PHX54662"/>
        <property type="gene ID" value="CP500_014860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="19017" checksum="864AF3400B363EBC" modified="2018-01-31" version="1">MKYDVCCGKKSPFTKSLFLFLIAGFGLIFVLQPEEYAALAQQAVCPKGDVADFPAPPLSQNQKSVPSLWLAQKQFGGQLLDRWFVDYNSSNSWVVLVVNRQLWSGLDYVGRYQFVNRFGVAAGEYGYNVRVCNRQGVGLAVYSCNGDRLSCRIDLESVSNPGIQRKPKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYT1</accession>
    <name>A0A2G4EYT1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54673">
        <property type="protein sequence ID" value="PHX54673"/>
        <property type="gene ID" value="CP500_014715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="225" mass="25218" checksum="79DFE408404E92CF" modified="2018-01-31" version="1">MNEMQGDQGFSMYRLRWVGYGLLILSLLDTIAVLTPANFGVRAWELQTIGAIVERVPVPLLAMALIFFGEGYDRKPLEDIFLKILSWVCLLLALVFLLMLPLGIFGAISVNTQSSKQITSQANQQLAQLQQIEERLNKGTPEDLKNLGAELTRLGVQADTKNPQELKSQILARITPAKERLQAQSTAVQSNQRLGLFKNAIKWLLGALISSVLFFMMWRGTDWAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ67</accession>
    <name>A0A2G4EZ67_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Isoleucyl-tRNA synthetase</fullName>
            <shortName evidence="11">IleRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ileS</name>
        <name evidence="18" type="ORF">CP500_014195</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54812">
        <property type="protein sequence ID" value="PHX54812"/>
        <property type="gene ID" value="CP500_014195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02002">
        <property type="entry name" value="Ile_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025564">
        <property type="entry name" value="CAAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023585">
        <property type="entry name" value="Ile-tRNA-ligase_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14159">
        <property type="entry name" value="CAAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1000"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="14">
        <location>
            <begin position="30"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="16">
        <location>
            <begin position="693"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="domain" description="CAAD" evidence="17">
        <location>
            <begin position="961"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="domain" description="zf-FPG_IleRS" evidence="15">
        <location>
            <begin position="1159"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="11">
        <location>
            <begin position="610"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="569"/>
        </location>
        <ligand>
            <name>L-isoleucyl-5'-AMP</name>
            <dbReference type="ChEBI" id="CHEBI:178002"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="613"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="1162"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="1165"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="1182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="1185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF06827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF14159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PHX54812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1193" mass="133359" checksum="49F646EAFCF1A87D" modified="2018-01-31" version="1">MEAKSYKDTVNLPQTKFEMRANAVKREPELQQFWADEQIYDRLSENNPGELFILHDGPPYANGQLHIGHALNKILKDFINRYQMLCGKKVRYVPGWDCHGLPIELKVLQDMKSADRLNLTPIELRRKAAAFAQQTVEQQRASFKTYGVWGDWEHPYLTLKPEYEAAQIGVFGQMVLKGYIYRGFKPVHWSPSSKTALAEAELEYPEGHTSRSIYVGFHVRILSKSLESNLNRYMSSLWAAIWTTTPWTIPANLAIAVNPELDYAVVEPPENSNIAQQFMLVAVDAVDRLSATFNTELKILATFKGKELEGCTYKHPLFDRESPIVAGGDYITADSGTGLVHTAPGHGQEDFIVGKRCGLPVLTPVDENGNFTAEAGVFAGLNVLGNGNGAVIDALAEANCLIKEESYAHSYPYDWRTKKPTIFRATEQWFASVEGFRDEALKAISSVNWIPAQGENRITAMVGDRSDWCISRQRTWGVPIPVFYDEETNEPLLNAETIAHVQAIIADKGSDAWWELSIAELLPESYRNNGRTYRKGTDTMDVWFDSGSSWAAVAKGRSELNYPADMYLEGSDQHRGWFQSSLLTSVATNGVAPYKTVLTHGFVLDEKGRKMSKSEGNVVDPAAVIKEYGADVLRLWVSSVDYSADVPLGKNILKQQSDVYRKIRNTAKFLLGNLHDFDPAKDAVPYEELPELDRYMLHRMGEVFAEVKDAFDSFQFSRFFQTVLNFCTVDLSNFYLDIAKDRLYISATDAHRRRSCQTVIAIAVENLAKAIAPVLCHMAEDIWQYIPYPTPYKSVFESGWVELDASWHNPELATRWQYLRQVRGEVNKVLEQARIQKTIGSSLEAKVLLYVPDAEKRLQLQGLNPSSEGLMDYVRSQNSIIELAAAEKAKAAQYQEEEKAANVAKVLTGTTIHVEAETIEKGDRPSVVIEYSAIEPSVTDSQPTFDFDKVAQFVANLPTYAGNLFTEYQKVFVTVGLIASVLVTARITARMLDTMNQIPLLGGVLEIVGILFTMWFAFRYLLFADNRQEIAEKISLLTADVVGKTTATGLGEKDAIALESLVESGIVETPEISTILRSKPVETVIVAIPEIPKTEVIAVVPESIPVMPDSKMVGNGVDELRYLFITSEVELIESNVVLQELPYSFQSPELAIGVVKANGEKCDRCWNYSTHVGESIEHPLICERCVSAVAGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ68</accession>
    <name>A0A2G4EZ68_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Thiamine biosynthesis protein ThiF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_014275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54786">
        <property type="protein sequence ID" value="PHX54786"/>
        <property type="gene ID" value="CP500_014275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028090">
        <property type="entry name" value="JAB_dom_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="PTHR43267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14464">
        <property type="entry name" value="Prok-JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prok-JAB" evidence="7">
        <location>
            <begin position="17"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="ThiF" evidence="6">
        <location>
            <begin position="330"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="628" mass="68545" checksum="5BE83AEF67AFAEF0" modified="2018-01-31" version="1">MLYISEEVLRQIERDIANHPPERGGAILGPVGQPIITHFLLDEQARTSGASYLPSPQLTQRVQQLELMEKVEFKGVIHSHPGGLDRPSGPDETAMLEGLNLNPHIPYFVAPIVTLQRYGGQLREHELPIAQGKISCYVASRDRNYLRVETLSVRSVRDRDLPRMLQTLSPTATPKRIPLQPDLQRLCQTFGSTQPPEIFVAEIEGQAIPAGRVILNGGLELLFLFSESYPVTPPLLMLTPFGGNTEEIKLDWSLETPPAERLLTAVQGMITGSGPYQKVYGPLGKSPIAADGDRARLAGWSGCYSGVDPKIAAAEIQQGLFARSQGILSQHLSTKRVLIAGTGSVGSYFAEQLVRSGVGALTLIDPETVEVANLCRTTYDFTDLGRLKVEALARRLLHINPLLELTVQPKSLSDYEVTAFDALVQAADLIIATTDDPAAQRILNRFAYFHGKPALFVGLYKGAEGGEVIVSLRDLTPCYLCATANRHQAEANLGRVSADGDYGNNGRVMGEVAIGADIQHVTSVAVKMALSLLLPEDAEAKLKGFLNPAIDGGLNYLTLSMVPNYWFYPGVFGDTPGQYAYQSVWLTAQRREECPVCGSVHHRVDPRQVPLKELQASDLRAALSRSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ84</accession>
    <name>A0A2G4EZ84_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54806">
        <property type="protein sequence ID" value="PHX54806"/>
        <property type="gene ID" value="CP500_014155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="237" mass="27448" checksum="3A6BD17BC11C1B08" modified="2018-01-31" version="1">MTAKKIACFVEGQTEQIFVEKLFQEIAGYKKISIETYKFQGGKTKRTIQPLKPSIVQDAPFFVLLYDCSSDSQVLSDIRKQHESLTNSGYEKILGLRDLYPISLSRKGEVERGIKGFLKPLHKMGIPISINLAVMEIEAWFLAEWHYLSKLDNRLIPDFILQECGYDLRSIDVEQRPHPSQDLDDIYQLIGCKYDKSEKISQEIITYLDYDFLYLELVSRVKQLKSFIGEIDSFLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ95</accession>
    <name>A0A2G4EZ95_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54820">
        <property type="protein sequence ID" value="PHX54820"/>
        <property type="gene ID" value="CP500_013910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="27"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="200" mass="22914" checksum="AFBE52FA341765DF" modified="2018-01-31" version="1">MNVYTLAKSTSPETEQDGCMMFYGVSWEQFEAIEAAFKDLKRVKFFYLDRILQIMTVSPEHEIIKKTLCMLLEAYMRANGIRFYGKGGPTLGNRELGGRKEPDDSYDIGTEKTVPDIAIEVVITSGGIDTLELYKRLGIREVWFWQNSQLSLYNLRGENYEQITRSTFLPNLDLELLLRCANMPDQYDAVTELLANISPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZN5</accession>
    <name>A0A2G4EZN5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PKHD-type hydroxylase CP500_013185</fullName>
            <ecNumber evidence="7">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_013185</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="7">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54970">
        <property type="protein sequence ID" value="PHX54970"/>
        <property type="gene ID" value="CP500_013185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00657">
        <property type="entry name" value="Hydroxyl_YbiX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041097">
        <property type="entry name" value="PKHD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023550">
        <property type="entry name" value="PKHD_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41536">
        <property type="entry name" value="PTHR41536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18331">
        <property type="entry name" value="PKHD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="77"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="223" mass="24940" checksum="10C53EBDAEAFF1A2" modified="2018-01-31" version="1">MIICMANILTSEELGLIVDRLKNAEFVDGKLTAGWYAQQVKNNAQLKNNAAPTQELRNLVNQALKRNSLFQIAARPKAIRPIMFSRYQGGMYYGTHIDNAIMGDEELMRSDLSLTLFLSDPATYTGGELVIESAQGEQAFKLDAGSMVVYPTTTLHRVEPVTEGERLAAVTWVQSLVRDAHNREILFDLDTVRDTLFQKSGKTAEFDLLSKSIANLLRKWADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZS7</accession>
    <name>A0A2G4EZS7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55013">
        <property type="protein sequence ID" value="PHX55013"/>
        <property type="gene ID" value="CP500_013050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="15"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="22661" checksum="21E674CD3445E601" modified="2018-01-31" version="1">MQTIAHPEKKVYTSEEYLEFEVNSEERHEYINGEIVLMTGGTPNHNQITGNFHAELNFGLKGQPYRAFVADQRLWIPGKRIHTYPDVMVVQGELQLEEGRRDTITNPLMIAEVLSKSTRSYDKDGKFAAYRSIPSFQEYLLIDQYEMHVEQYFKTDGNSWTFSEYDDANVTISLKSLSFQFTLADIYDKVDFESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZW3</accession>
    <name>A0A2G4EZW3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GlsB/YeaQ/YmgE family stress response membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_012815</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0410 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55043">
        <property type="protein sequence ID" value="PHX55043"/>
        <property type="gene ID" value="CP500_012815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007341">
        <property type="entry name" value="Transgly_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33884">
        <property type="entry name" value="PTHR33884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04226">
        <property type="entry name" value="Transgly_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="8745" checksum="D03C66D8BA198366" modified="2018-01-31" version="1">MGIIAWIVLGLIAGAIAKAIYPGQQGGGFLATTGLGIVGALVGGYLGQVFVGTSAGASFGALTLPSIAFAVIGAIVVLFIWGLLTQRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZW9</accession>
    <name>A0A2G4EZW9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54747">
        <property type="protein sequence ID" value="PHX54747"/>
        <property type="gene ID" value="CP500_014495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="3"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="165" mass="18227" checksum="12D1ECBDE225E74A" modified="2018-01-31" version="1">MTFKKIFAALDESELSHSVFSQTLELAQANQAEVMLFHCISVNTLGQSAVPIPVDLGMNVQLMDQAYQAQRLLRETELKQSESLLKKYCDAAANQGVQVEFDSQMDGDPGHCICEYAQNWGADLIILGRRGRTGLTEAFLGSVSNYVVHHASCSVFVIQEPKSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZY4</accession>
    <name>A0A2G4EZY4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55066">
        <property type="protein sequence ID" value="PHX55066"/>
        <property type="gene ID" value="CP500_012650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1" evidence="2">
        <location>
            <begin position="93"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="559" mass="64043" checksum="7EEFD77689FF77B0" modified="2018-01-31" version="1">MLTKAAPKTLRWQRSQYSPLARQIDVFAAAAKFIFCLWWDGLLQNKSAHTRRIRAHWLVNTLLDLGPTFIKIGQSLSTRADLLPLEYVKELEQLQDRVPEFSSEEAIALVESELGKDIYALYRDFDPFPIAAASLGQVHKARLHTGEDVVVKVQRPGLKKLFDLDVKAVRQVMNLCNNYFPWIRKYDLESIYDEFFKILYQEIDYVQEGKNSDRFGANFQGYPRIIVPKVYWQYTTKKVLTVQYAPGIKVDDRISLEAMGVDVAKLNQLGICCYLKQLLLDGFFQADPHPGNLAVTEDGSLIFYDFGMMGEVKSLAKDEMVKTFFAVMRKDSDEVLDTLIAIGLVDPMPDMMPVRRLITFLLDRFIDKPIDFQAFNEIKNELYIMFEQQPFRLPAQMMFIVKSLTTLDGIARTLDPDYNFLASAQPFVKSIAISKGRGNTVGELARQARDFIRYKLQQPSKSEVLFKRLEQRIQDGELQIRVRNIESERALKRINLALKTLIYACLTGFVLLTGTVLLLGGYRREAMAAFGLSGFGSLFLLHSFLDLLIKEKLDKIVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F001</accession>
    <name>A0A2G4F001_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55081">
        <property type="protein sequence ID" value="PHX55081"/>
        <property type="gene ID" value="CP500_012725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8229" checksum="EF265E7427076548" modified="2018-01-31" version="1">MTIVIALLIVGWVAASVIGTQAYFLGEQSKPIHDRNWDSESFEKLAVAVTGTEIDYSVRVPAYSMDAYGSRTMSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F017</accession>
    <name>A0A2G4F017_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55101">
        <property type="protein sequence ID" value="PHX55101"/>
        <property type="gene ID" value="CP500_012565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="26"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="376" mass="43431" checksum="14C665F96E48CF59" modified="2018-01-31" version="1">MRIKKFAFWDNLREWRFEPIYFSNLALLVGVSGVGKTKILEGILSLQKIANGVSLNGLAWDITFSTVNDDLDDVEYRWQGEFETKKNLPRILNEEDETNQFRIVREHLLMEEDIIIERTPNEIIFQGQKTPKLSPFQSVVKILNQEDDVSPAYYAFLYKIISNNSSSMDYYDMNYTAILNLQKSESLLMAIKETDMPLQIKLAFICSHYSDLFNQIKRIFIQAFPQVEDLKIQPVQDDESSFISFPIQIKEKGVNDWIFQNNISSGMLKTLIHIAELYLSPEGTVILIDEFENSLGINCIDVVTDLIVENRNIQFILTSHHPYIINNIGMEHWKIVTRKGGIVTAIDAKDLNLGKSRHQAFMQLMNLEEYSEGIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F036</accession>
    <name>A0A2G4F036_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55108">
        <property type="protein sequence ID" value="PHX55108"/>
        <property type="gene ID" value="CP500_012600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="12199" checksum="713F7BD24215F8D5" modified="2018-01-31" version="1">MRGVKTWQEADISPEDARRIQNAADRTKQIIIVVGSRASGTNRLTSDWDYIMLGNSRQRHSAWSSVPHGTSGGEINSSGRETGIDIFTGPLISGEPHVIFEPKLGEANESHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0A9</accession>
    <name>A0A2G4F0A9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polyamine ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_012065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55190">
        <property type="protein sequence ID" value="PHX55190"/>
        <property type="gene ID" value="CP500_012065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006061">
        <property type="entry name" value="SBP_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019574">
        <property type="entry name" value="Periplasmic_polyamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01037">
        <property type="entry name" value="SBP_BACTERIAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Spermidine-binding" evidence="4">
        <location>
            <begin position="197"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR019574-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="376" mass="41960" checksum="4700B39083AC512E" modified="2018-01-31" version="1">MPPTNLPISRISRANSTRRQFLKNSAATVSGLALSSCGWRLADVQSAPPVKGNADQLFIYTWAGYTDKALLDRFAEKTGIRVIADVFDSNESMLARVQAGGGRAYSIIYPSDYMVIQMKELGLLSQLDHSILGGLDRLKKQFQNPVYDPGNRYSVPLSWGTTGLIYNSEQLKEAPEDWDYLWKHKKELTRRMTLANDVREVMGAALRMQGYSLNSTNPEQVKKAYEKLVELKPSIASFTTDAWRPQILTGDLKVAMCYSSDANEVIPDNEKLRYVVPKSGSSLWTDTLVIPKSAPNPEAAYKWINFMLQADVAASLVERLSFSTPSEDAFSLLTPEVRANEILFPSEATLKNCEGVAPVGKFIDVYDRYWTKLTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0E4</accession>
    <name>A0A2G4F0E4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA/RhaT family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55231">
        <property type="protein sequence ID" value="PHX55231"/>
        <property type="gene ID" value="CP500_011875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="24"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="167"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="34892" checksum="FB275C4A9FDE9570" modified="2018-01-31" version="1">MQTSTYRQFVSKELIALGFGILAITFAPILIKISSQELGANAIVFHRFWVATLVLGIWNRIKIEKNQENEIDSEQLQPKTTENWLLLLGAGVADAFCMVAWAWSIERTSIAHSTLLHNLTPIFTTLGGWLFFGQYFEMKFLLGVAITIGGSIAIVLEDWQLASGSFIGDQAALFSAIAYSIRLLVIERLRDRLSTATIILWISLITTLAVIPTALLFEERIFPGSWLVWIAVILQGLLCEVIGQGAIAYSLKRFSSGFVSLCLLLEPFLAAILAWFIFVQELSILDMFAFPVILLGIYLAKSSEGSEKSGLQDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0E8</accession>
    <name>A0A2G4F0E8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55226">
        <property type="protein sequence ID" value="PHX55226"/>
        <property type="gene ID" value="CP500_011850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="206" mass="23384" checksum="097455DFC3468CC5" modified="2018-01-31" version="1">MIQALPKLVNFEEFVERLPENSAVRYELHNGDIIEIAQPVGEHEEVISFLSIEIPVEIKRLGLPYGIPRQVIVRPPEKDSGYFPDVLVLNRANLGKETLWQKQSTLSLGASIPLVIEVVSTNWRDDYHLKYADYEEMGIPEYWIVDYAALGGRNFIGNPKQPTISVCNLVEGEYQIVKFRDNDRIVSQVFPDLNLTANQIFQAGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0E9</accession>
    <name>A0A2G4F0E9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease adapter protein ClpS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">clpS</name>
        <name evidence="3" type="ORF">CP500_011900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds to the N-terminal domain of the chaperone ClpA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55235">
        <property type="protein sequence ID" value="PHX55235"/>
        <property type="gene ID" value="CP500_011900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00302">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473">
        <property type="entry name" value="PTHR33473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ClpS" evidence="2">
        <location>
            <begin position="30"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="12100" checksum="EF91238D1BECB009" modified="2018-01-31" version="1">MIFVLSVAVRAMTSSPTIAPVRSSQVTRKPYPNYRVIVLNDDFNTFQHVVDCLTKYIPGMTSDRAWDCANQIHNEGQSTVWVGPQEQAELYHMQLSRAGLTMAPLESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0R5</accession>
    <name>A0A2G4F0R5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55353">
        <property type="protein sequence ID" value="PHX55353"/>
        <property type="gene ID" value="CP500_011175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="7911" checksum="AD752303B6A50A47" modified="2018-01-31" version="1">MSYFAGWAITLTSEGAAMPLNVQFTNWPWDGILGVGESGIGSQQNVENCNVFSSYGTAFEKPGLIRHLLKSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0R7</accession>
    <name>A0A2G4F0R7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1832 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dndE</name>
        <name evidence="1" type="ORF">CP500_012835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55047">
        <property type="protein sequence ID" value="PHX55047"/>
        <property type="gene ID" value="CP500_012835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014969">
        <property type="entry name" value="DNA_S_DndE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038472">
        <property type="entry name" value="DndE_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08870">
        <property type="entry name" value="DndE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03184">
        <property type="entry name" value="DNA_S_dndE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="133" mass="15035" checksum="1F27408424A6CA50" modified="2018-01-31" version="1">MEPPVDRIRLSQTGKDQLSKLKRSTKIDQWNILCRWGFCRSLAEPSIPSPVPIPSDSNVELSWDVFGGHMADILIIALKQRCHQDNLGTEKETLAKQFRLHLHRGIGYLAGDPNIKKIEDLVAIALSPEKLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0U5</accession>
    <name>A0A2G4F0U5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55382">
        <property type="protein sequence ID" value="PHX55382"/>
        <property type="gene ID" value="CP500_010940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="212" mass="23734" checksum="4A9CBA34BBC05DDA" modified="2018-01-31" version="1">MSINKAVKSRANKSTAGFTITELLAVVLVIGIVSAISVPSWLMFINNYRVKTSIDRVYWAMEIAQSNAKRDKVSWQVSYKQVGKTVQLAIHRSDIPPAQLPAGEWKSLEPDIEINTAKNDKGESETTLLPINDQNEHKENGTIRRAMFNFQGCPVYKSTDDCGLTSLRAKGRITLSHPDLPNGDRCVIISTVLGHTRMGEKHKKAEDKRYCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0X7</accession>
    <name>A0A2G4F0X7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_010860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55434">
        <property type="protein sequence ID" value="PHX55434"/>
        <property type="gene ID" value="CP500_010860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="39"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="453"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="488"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="530"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="572"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="654"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="688" mass="74208" checksum="DB4B23667F0028CC" modified="2018-01-31" version="1">MASVSYCLNPKCPNPSDPANAGKSACLHCGSQLFLEGRYRLVAPLGGGGFGKTFEVDDNGTRKVLKVLLKEHPKAVELFKQEADVLVKLRHPGIPKVDRDGYFIFSPANSTESFHCLIMEKIAGANLQDWLKHRGRPITQELAVNWLKQLSEILDLVHRLNYFHRDIKPHNIMCKPNGQLVLIDFGTAREVSATYFAKVGQGGNVTGIVSPGYTPPEQTNGKAVPQSDFFALGRTFVYLLTGKPPTAFPENPRTGKLMWRKGAPQVSDPVANVIDYLMAPFPGNRPQSPQVILQCLEEINLDEAETEFPTQLPTTGQTKIRGNPGLSGMKQSSINRLKPLNSDLKKSGLDQFEWKNKLLAGAAVVVLAICGSQIYGSVRYKVFPANPIWLASSWSSSQFLESSLDNVGSVNAIAISSDGQTLVSASFGTIRIWNVRTGGVVRTLNPVHSKKSVKALAVSPNGKILASGGDDNNVILWDLKNGRRILTIPGHNGGVNAIAFSPDGQTIASGSDDKTVRLWNAKTGGRLLTLSGHGGGVNAIAFSPDGQTLASGSEDKTVRLWNVQNGDIRRILAGHGQAVNAVAFSPNGQVVGSGSSDNTIRLWNVQNGKRTRTFEGNGSWVRAIAFSPDSSTLISGGADLIVWDLKTVQERITLSGHSQFVSSIAISKQGNILVSGSPDRTIKIWQIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F161</accession>
    <name>A0A2G4F161_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55492">
        <property type="protein sequence ID" value="PHX55492"/>
        <property type="gene ID" value="CP500_010315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="8"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="180" mass="21745" checksum="ABE2654661FA103E" modified="2018-01-31" version="1">MQYRRLKTPGATYFFTIVTYQRQCLFSDPEMVELLRAAFRNVIARFPFIIDAIVVLPDHLHCIWTLPDQDANFSTRWRLIKNYFSRNCPEQYKQNRSVSRLKKGEQAIWQRRFWEHQIRDEVDFANHVDYIHYNPVKHGLVAAPRDWEYSSFHRYVQDGSYPRDWGANILIEWENEVGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F162</accession>
    <name>A0A2G4F162_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiamine biosynthesis protein ThiF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55486">
        <property type="protein sequence ID" value="PHX55486"/>
        <property type="gene ID" value="CP500_010655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="33"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="206" mass="22965" checksum="EB494B9F4E4EA5D5" modified="2018-01-31" version="1">MIYTFKPQPRNFEGWGIFKPVNEKIAGVVDEPNLPRSGFCQLRVVDRDRIEERNLSTQPYYRSDVGAFKAKILANNLYRALGVKIEAHSKELTSANSDRRLANSAAIVDTFDNSVGRQALKDYSTSADIPCVHVGLAADYSEIIWNQHYRVPSPANDDVCDYPLARNLVMLTVAVACEVIVGFVATKEQQNLTCTIGDFAVRPLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F183</accession>
    <name>A0A2G4F183_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55512">
        <property type="protein sequence ID" value="PHX55512"/>
        <property type="gene ID" value="CP500_010420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="8336" checksum="64582E78D3E2A642" modified="2018-01-31" version="1">MIAKKTTVKTKVKKDINDSPEVIINKAKMLEQSPKPEAKELRTNNCTLDIILFLNLHLNYSVFQVYEVLSISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1N6</accession>
    <name>A0A2G4F1N6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF455 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55658">
        <property type="protein sequence ID" value="PHX55658"/>
        <property type="gene ID" value="CP500_009615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007402">
        <property type="entry name" value="DUF455"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04305">
        <property type="entry name" value="DUF455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="295" mass="33895" checksum="92892673B9E3C93E" modified="2018-01-31" version="1">MTVAYPRKLRNGMGAREILAQVVRDREIHLITLNRYRFSEQRSCKDLTDLIEQLDGNPAELVRDLSRHISDEARHAMWLTDLLVDIGCGIGKPPGVSYIDEFERLYDSEQQDPTKDREDFVISSLAAINVTEKRGCEYFSAHIHALKMAPQTDENVKIRETIEKIFPEEAGHVRWGNRWLGKIAAKSPAHAQKVEQAKRKYVAIEQAAFASGMDIMLGAELRRFTRLVDIANTMPMWERPQYLMERLAGTLLAPDLQMTRVDVAQRAWNRDPQAFVEKFVPMFLNGMNNSQKKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1R5</accession>
    <name>A0A2G4F1R5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Diadenylate cyclase</fullName>
            <shortName evidence="10">DAC</shortName>
            <ecNumber evidence="10">2.7.7.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cyclic-di-AMP synthase</fullName>
            <shortName evidence="10">c-di-AMP synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dacA</name>
        <name evidence="12" type="ORF">CP500_009455</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably a homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the adenylate cyclase family. DacA/CdaA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.85" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55710">
        <property type="protein sequence ID" value="PHX55710"/>
        <property type="gene ID" value="CP500_009455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019932">
        <property type="term" value="P:second-messenger-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01499">
        <property type="entry name" value="DacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014046">
        <property type="entry name" value="C-di-AMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034701">
        <property type="entry name" value="CdaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004793">
        <property type="entry name" value="UCP004793"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00159">
        <property type="entry name" value="TIGR00159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="DAC" evidence="11">
        <location>
            <begin position="87"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX55710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="306" mass="33552" checksum="2F2298082FF4E5E1" modified="2018-01-31" version="1">MNNQQSGYDFGLIQSLLIQAIDIGLVFALAYLVLVIVGERRTLWMVRGFIILMLAAAVSNWAGLRLLHVALNSLVTGSAVAMAVILQSEFRRFLEQLGRGEIVQLFGRDRRPTPAPDSVIDEIVDAVKELSQNRTGALLIIETDSPIDDRDFSVPGVKLNAEVSKELLQTIFQPQTLLHDGAVLIRASRIVSAGVILPLSDRTASRQLGTRHRAAMGITERVQACVCVVVSEETGSISLAFMGTLNRPLTSTKLKELLEAKLFPSEGERAVAPIPIGNFGRQIGLKVWTLLKRILRRPSSANREKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1S5</accession>
    <name>A0A2G4F1S5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55702">
        <property type="protein sequence ID" value="PHX55702"/>
        <property type="gene ID" value="CP500_009405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="5"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="193" mass="20472" checksum="D3BB765F783C1B65" modified="2018-01-31" version="1">MNNTPKILAFAGSTRTASYNKMLVKIAAAGARNAGAEVTYIDLRDFAMPLFDEDLEAAEGMPENVRKFKELMIAHQGLLIASPEYNSSITPVLKNAIDWASRPLPGEAGLAAFNNKVAAIMSASPGGLGGMRGLVHLRSILGNINVMVIPDQKAISQAFQAFNPDGTLQDVKQQEAVQHLGAKLAGILAKLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1T8</accession>
    <name>A0A2G4F1T8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal-protein-alanine N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rimI</name>
        <name evidence="2" type="ORF">CP500_009465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55712">
        <property type="protein sequence ID" value="PHX55712"/>
        <property type="gene ID" value="CP500_009465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006474">
        <property type="term" value="P:N-terminal protein amino acid acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006464">
        <property type="entry name" value="AcTrfase_RimI/Ard1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01575">
        <property type="entry name" value="rimI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="215" mass="24605" checksum="48FDDAFFAEB2EE16" modified="2018-01-31" version="1">MCFLKIKHLAPEHLPSAVELDRLCFGGLWAIEGYRRELDSPNSDLLGLWTWETEDCESGQNRAGTGTPPLQIRAGTGAPPLQIRPMLIGVGCLWAILEEAHIIMLAIHPSFQRQGLGQTLLWALLKSACDRQLERATLEVRDSNLAAVSLYKKFGFKEAGRRKRYYEDTGEDALVMWRSGLEKPEFQEYLAVEERQMRDRLHEKNWHLAIDDFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1X8</accession>
    <name>A0A2G4F1X8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55752">
        <property type="protein sequence ID" value="PHX55752"/>
        <property type="gene ID" value="CP500_009095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="7273" checksum="619DEAA2D147B343" modified="2018-01-31" version="1">MSEITLDETKLKELLKAAIFELLKEQKEVFYEILTEALEDIGMENAIKEGENTETVSREQINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Z4</accession>
    <name>A0A2G4F1Z4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase</fullName>
            <ecNumber evidence="6">2.5.1.147</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">FO synthase subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cofH</name>
        <name evidence="8" type="ORF">CP500_009030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine = 2-iminoacetate + 5'-deoxyadenosine + 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:55200"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:77846"/>
            <dbReference type="ChEBI" id="CHEBI:85936"/>
            <dbReference type="EC" id="2.5.1.147"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme F0 biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The FO synthase complex consists of two subunits, CofG and CofH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. CofH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.147" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55781">
        <property type="protein sequence ID" value="PHX55781"/>
        <property type="gene ID" value="CP500_009030"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00072"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044689">
        <property type="term" value="F:7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01612">
        <property type="entry name" value="FO_synth_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045567">
        <property type="entry name" value="CofH/MnqC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019940">
        <property type="entry name" value="CofH_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034405">
        <property type="entry name" value="F420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020050">
        <property type="entry name" value="FO_synthase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43076">
        <property type="entry name" value="PTHR43076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19288">
        <property type="entry name" value="CofH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00293">
        <property type="entry name" value="((2_3_4_5-tetrahydroxypentyl)a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03551">
        <property type="entry name" value="F420_cofH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00423">
        <property type="entry name" value="TIGR00423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="50"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="385" mass="42036" checksum="BC631D2B89209FD8" modified="2018-01-31" version="1">MDAILDRALQGYNISTADALVLLQQKEPNAIASIQTTADLLRRRQSGDTVTYVINHNINFTNICEQHCSFCAFRRDDGDEGAFWLNAAQIIEKASDAVQRGATEICMQGGLNVQAKLNGASLPYYLQLVKTIKDKFPQLHLHAFSPQEIEFISRKDNLSFSYVISALRDAGVGSMPGTAAEVLDDAVRRVICPEKLNSASWLKIVGTAHSLGLPTTSTMLCGHIETAEQQVLHLEKVRSLQQSAIHNNYPARITEFILLPFVGQSAPAPLRSRVGRDQPVLADTLLLTAVSRIFLGNLIPNHQPSWVKLGLDGATEALKWGCNDIGGTLMEEHITTMAGAVGGSCQSVEDLQNAISSLGRSYQQRDTIYRPLGVDKLAAVSSKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2E0</accession>
    <name>A0A2G4F2E0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polyphosphate:AMP phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pap</name>
        <name evidence="2" type="ORF">CP500_008040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55916">
        <property type="protein sequence ID" value="PHX55916"/>
        <property type="gene ID" value="CP500_008040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043751">
        <property type="term" value="F:polyphosphate:AMP phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022489">
        <property type="entry name" value="PolyP_AMP_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03708">
        <property type="entry name" value="poly_P_AMP_trns"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="PPK2" evidence="1">
        <location>
            <begin position="269"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="495" mass="58162" checksum="C3414CB64E7A5D5A" modified="2018-01-31" version="1">MLDNLDLDISLDKETYDAKIEVLMQKLRSLQQACWEKKLPIIIVLEGWAAAGKGALVKKMVGYMDPRGFTVHPIWPPSDAELGYPFLWRFWQKLPARGRIGFFYHSWYTHVLEDRLFDRVSDAQLPTIIRQINSFERQMVDDGAAIAKFWIHLSKKELKHRLKKLEEDSLQAWRVRPEDWKQAKKYTEYKIFAEEMVAQTGTGPAPWTLVEGDCQRWGRVKVLTQMASTITEALDRQTMQSAPIQLPHQEHLQPTEPDLLAQVDLTQSLSPEEYKQQLREEQTRFGKLQQSIDEHQIPVLVLFEGWDGAGKGGAIKRLTDILDPRSYTVNPFAAPTDEEKAHQYLWRFWRKLPTAGKISICDRSWYGRVLVERVEGFATEPEWRRAYQEINEFEEQLTSFGCVLVKFWLHISPDEQLKRFTDRQNNPFKQYKLTDEDWRNRQKWNFYEVAVNQMIQRTSTPTAPWTTIAADDKYYARVKVIQTVTQAIRNQLKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2F9</accession>
    <name>A0A2G4F2F9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55936">
        <property type="protein sequence ID" value="PHX55936"/>
        <property type="gene ID" value="CP500_008155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="167" mass="19165" checksum="74424A1554EAAF82" modified="2018-01-31" version="1">MARQLILAIAESAESLEQQLKNSRTASQKERLQMLWWLKTGQITQHQTLAKRLGRDGSTVTRWLQKYRQGGLSELLVVKSAPGKSPHLSSEALAGLQKRLEQPPGFKSYGEIVEWLNETYQLNLTYPTVYHWVHYRLKAKLKVPRPKSAKQEPNADRRFKKTSAQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2J0</accession>
    <name>A0A2G4F2J0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_007905</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55962">
        <property type="protein sequence ID" value="PHX55962"/>
        <property type="gene ID" value="CP500_007905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012837">
        <property type="entry name" value="NrdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352:SF2">
        <property type="entry name" value="PTHR30352:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00299">
        <property type="entry name" value="anaerobic_ribonucleoside-triph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="211" mass="23338" checksum="2F7733AA01DF34C1" modified="2018-01-31" version="1">MKPHKTNPYVQLLDIPPGYLNIMGYVDESEVNGPGCRAVLWVQGCLRECTDCFNPASWSFEINQLIAVDVLVQQILRNPRNQGVTFSGGEPFWQAPALADLARQVKAAGLNVMSFTGFTLEQLRSEQGPAGVENLLEQLDILIDGAYVQSLAVNSPDSLVSSSNQRVHLFNPALQDQLTWASDQMEIHILKDGSRIFTGYRGQLNLADSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2P9</accession>
    <name>A0A2G4F2P9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">High light inducible protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56015">
        <property type="protein sequence ID" value="PHX56015"/>
        <property type="gene ID" value="CP500_007625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="47" mass="5123" checksum="FBF4318590CA3EE4" modified="2018-01-31" version="1">MENKDAKVGFTEFAETWNGRLAMLGFVIGLATEYITGQGILSQIGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Q2</accession>
    <name>A0A2G4F2Q2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56054">
        <property type="protein sequence ID" value="PHX56054"/>
        <property type="gene ID" value="CP500_007425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="2">
        <location>
            <begin position="297"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="359" mass="40554" checksum="8378DB7E2A525783" modified="2018-01-31" version="1">MKFISPKTDFAFKKIFGSTDSQDILISFLNALIYGGEPIIQDLQIIDPYSAGIVSGQKDSYLDVKARITGNTTVIIEMQVLNVEAFEKRVIYNLAKTYANQLKIRDGYPRLQPVIALTITDFKMFKEQPDVISHFVFKEKEKLFDYPHLQLEMFFVELPKFNKELDQLTTLTEKWIYFMKNTPDLEAIPATMETVPELEKAFRIANQANLSLEELQNMEAQEMALEEERGIITRGIREGIRDGLELAKIQLMQEGIEAGRQQGIEAGRQQGIEAGRQEGIEAGRQEGIEAGRQQGIEAGIKAGQTALILRLLERRIGTVNPDVVSRIGELSVEQLESLVDEVVGFSSLSDLMGWFEENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F317</accession>
    <name>A0A2G4F317_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56163">
        <property type="protein sequence ID" value="PHX56163"/>
        <property type="gene ID" value="CP500_006880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="29979" checksum="9C0FE24E8C486F37" modified="2018-01-31" version="1">MRCFSLTQVQVMTSNQSALAKLLCGNLVPDRGGIDEVLSHLSSSIDNVVIELIRLESLTPNQISLFAPFLGRSILELGCTALIARLDPFRVLLIREYQKQPNYLDSLMDKPNKSSIRWQGDVFADKVTDILADKSLQNPTRALLGDYYKTLIWSANFDELQDAIRDVSGDEWIIDLRQKDFARFYNETLSDFSSLYSKLSKGIHHELVIPLSSAFDQETTRLLIQKTVRNIATLGLFVSVVSHTVNKLDIQEAIAAYKEIQEIGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F360</accession>
    <name>A0A2G4F360_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56189">
        <property type="protein sequence ID" value="PHX56189"/>
        <property type="gene ID" value="CP500_006685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="45"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="206" mass="23815" checksum="32323C33BE3DB4E1" modified="2018-01-31" version="1">MYSDPVQREYSRLAKQYDSRWAFYINTTIGETLNRLEINQGERILDLGCGTGVLIQRLLQVSPEIEVAGIDACAEMLEIAKQKLPESVELKLGSADNLPFPSNYFDIVISTSAFHFFRDPSQALQEAKRVLKPNGRLVITDWCYDYLTCKVFDFFLRCFNRAHFRTYGVSEFQAMMQNEGLQGIAIERYKIDWFWGMMTATAVNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F367</accession>
    <name>A0A2G4F367_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-regulated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56188">
        <property type="protein sequence ID" value="PHX56188"/>
        <property type="gene ID" value="CP500_006680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="66"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="200" mass="22434" checksum="DCC686AD8223A8F3" modified="2018-01-31" version="1">MKYYSKHPNAFSITYLNDLRGAILASPYFAINNLNRDFIGTKGFSVVFQRSEIAQVEQRFPAFKPYLDQALQPACNAFYLNPLLLKEGSRVDPHIDRSLRSYCKTVEPPATVSVLYVQVPANLEGGELVLRCHKKQVGQIKPEANTLVYFQGDLTHSVNAVTSAGTRLSLVCEQYSLSETELADIPEFTLESRTVKVKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3B1</accession>
    <name>A0A2G4F3B1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hybrid sensor histidine kinase/response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_006400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56236">
        <property type="protein sequence ID" value="PHX56236"/>
        <property type="gene ID" value="CP500_006400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="158"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="377" mass="42032" checksum="211CB4759FEE9ADC" modified="2018-01-31" version="1">MSQFSILIVDDEPDNFDVIETLLSEQDYQLHYAASGQEAIASLDIFDPDLILLDVMMPGIDGIEICRQIKAIPKWQAVPIIMVTALNRKSDLANCITAGADDFITKPVNAIEMRARVHSMLRIKKQYENIQNLYHIQENTINVLENTLNELRGNLASSLSHELNTPLNGILGTIGLLKDDLEDMDIAEIHEMLGWADQSARRLKKLTKKFLIYLELELSASRQQKIEFTGTKFSASAIEAALKSQAQSVNRNNDIVLALEEAEIGLSERYLSMIVYQLVDNALKFSSPETTIKVSSKVVGKMLNLSVHDSGRGMTEEQIAKIGAFMQFERKTYEQQGIGIGLKIVMKIVELAGGGFSITSIYQKETTVHLTLPIVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3F5</accession>
    <name>A0A2G4F3F5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CNNM transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56289">
        <property type="protein sequence ID" value="PHX56289"/>
        <property type="gene ID" value="CP500_006285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="CNNM transmembrane" evidence="2">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="284" mass="30990" checksum="A6F56BAE2FDD64B1" modified="2018-01-31" version="1">MLRLAMLLGLTLLIAFFVASELALVSADRHQIRQLAQLSDAPKIAKAAQLVHQAQNDIPHYLSVTQTGTTAGSLLLGWLGEGATVHWIEPWLDKLPLGHLPAMLTAHAIAVPLAFILVTYVEIVLGELIPKVLATHEPERTALLLTPALQICSNVLWPLLAVLNGTVRLLTGWITSNKSQPLLSPSEATLVQNDAHSVLLSGIWEVTAVNEKFGLNLPINQAYQTIAGFMIHQLGKLPNQGERLLWGELEIEAANVVEGSLETVLIRQVTRPLFETQQPELVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3T2</accession>
    <name>A0A2G4F3T2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4-hydroxyphenylpyruvate dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hppD</name>
        <name evidence="7" type="ORF">CP500_005430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4HPPD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56444">
        <property type="protein sequence ID" value="PHX56444"/>
        <property type="gene ID" value="CP500_005430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="PTHR11959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="2"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="146"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="358" mass="40257" checksum="30076EBA2BE0428C" modified="2018-01-31" version="1">MEFDRIHFYTQDAAALRDWFVTKLGFQATADYQNRHTHTEVVNSGNICFVLSSPLTPASPVSSWLRLHPTGIADVSFRVKNLELAMARAATQGAKVLQPIQEGFKVGGCFKWAKIAGWGDLSHTLIEGIGENPLPPNSLNLPLFTKIDHIVLNVETGDLSTAVDWYQRVLGFQAEQNFDIQTEKSALRSRVMVHAEGGVQLPINESASANSQIQEFLDANRGPGIQHMALQTDRIVGVVTDLRSRGLPFLPVPWTYYTELQKHQNYVPTDWQEIVACQVLADWQEDTPAAMLLQIFTQPIFAEPTFFFEIIERRFALVNDQKVQAGGFGAGNFRALFEAIEREQMKRGSLRDDSDFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F441</accession>
    <name>A0A2G4F441_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56553">
        <property type="protein sequence ID" value="PHX56553"/>
        <property type="gene ID" value="CP500_004710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="189" mass="21621" checksum="693FAC4FDED44C3D" modified="2018-01-31" version="1">MQIKGIKRGNIIEISENLNIPDGSEVLLEVREVSPVNYEKKLAKMKEFLAGLSDEDREEWRKIGEFLESERAINRQLSVLSHKTQGRSPLFGSDRRLITTSDDFDESLELLPSPLVDSLLEKAKELTQVSAELTEIIAKIEKQRQIEQPQNFWEAIQKFRQENNLEEAGIEAEVFDGLRDSSPGREVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F477</accession>
    <name>A0A2G4F477_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SRPBCC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56549">
        <property type="protein sequence ID" value="PHX56549"/>
        <property type="gene ID" value="CP500_004685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="18011" checksum="4F564A13E1BFF48A" modified="2018-01-31" version="1">MLVKTNAFVEIAASPEVVFDFVTSLSNLPKVFHGYGPIPAIIKAEMADGGEMREGGVRRIENSDGSVIDEEIINFNKPERQTYRLVRGFKFPISLLIESGGGDWKFTATAKGTRIDWEFYFMLTSPLFYPVGLLLVQVFMQTAMQQCLDNIQEYLTNQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4A3</accession>
    <name>A0A2G4F4A3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF309 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56613">
        <property type="protein sequence ID" value="PHX56613"/>
        <property type="gene ID" value="CP500_004575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005500">
        <property type="entry name" value="DUF309"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023203">
        <property type="entry name" value="TTHA0068_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34796">
        <property type="entry name" value="PTHR34796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03745">
        <property type="entry name" value="DUF309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140663">
        <property type="entry name" value="SSF140663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="136" mass="15259" checksum="1F19797D3BFCD7C9" modified="2018-01-31" version="1">MEEEMSVEFWQGIEEFNSKEFYACHDTLEALWMEAGDPNKRFYQGILQISVALYHLGNQNWRGAVILLGEGINRLRYYQPSYAGIAVEDLVQQSAKLLNALQQAGSERVAEFLPLLSGGEVAGLQLPCIVKDYSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4K0</accession>
    <name>A0A2G4F4K0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56665">
        <property type="protein sequence ID" value="PHX56665"/>
        <property type="gene ID" value="CP500_003995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="50"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="84"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="118"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="152"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="186"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="220"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="254"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="288"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="322"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="356"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="390"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="449" mass="51310" checksum="C913679F76642A7D" modified="2018-01-31" version="1">MTQESEKRQACWERWNREDDLALTPQERKRELVRIQVLIDEYSPTPEQKADLFLEQGLLYSFGEEYAKAIASYDKALEIKPDDRKAWYKRGNALGNLGRLEAAIASYDKALEIKPDLHAAWYNRGIAQRNLGLFESAIASYDKALEIKPDDRKAWYNRGIAQRNLGLFEAAIADFDKALEIQPDLHAAWNIRGGTLYNLGLLKEALLSFDKALEIKPDLHKSWYCRGYALYKLGLLKEALASFEKALEIKPDLHKAWNNRGIALGNLGSLEAAIASYDKALEFKPDYHEAWSNRGYALRNLGLLKEALVSYDKALEIKPDLHKAWYCRGSALLNLGRFETALVSYEKALEFKPDLHKAWYYRGIALYKLGLFEAAIASYNKSLELKPDDREAFYNKAGCHGLRSQIDQAIQNLQQAINLNPDKCRERAKTDSDFDSMRSDIRFQALIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4M4</accession>
    <name>A0A2G4F4M4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-beta hydroxysteroid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_004125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56688">
        <property type="protein sequence ID" value="PHX56688"/>
        <property type="gene ID" value="CP500_004125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="PTHR43078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="354" mass="38641" checksum="7352D6BB1130E3C9" modified="2018-01-31" version="1">MVERILIVGGAGFIGSCLAIGLKKLHPELQIICLDNLRRRGSELNLPRLKSSGIQFVYGDIRCAADLDPVALNVDCIIDCAAEPSVLAGFSSPQYVLQTNLLGTVNVLELARQTGASLLFLSTSRVYPIASVKSIRLLELESRFAIAPNQTIPGISELGISEDFPLKGHRSLYGATKLASELLIEEYRAAYNVPAIINRCGLITGAWQMGKVDQGVCGLWVAAHYFQKSLNYIGFDGSGKQVRDLLHIEDLLRLIDYQLENFAEFDGEVFNVGGGLINSLSLVETTDLCQKIVGKSIPIHPVLEERAGDIPIFITDSSRVMERTGWQPAIGPEAALQDIYDWIVANEVVLSSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F525</accession>
    <name>A0A2G4F525_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56872">
        <property type="protein sequence ID" value="PHX56872"/>
        <property type="gene ID" value="CP500_003085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013633144" evidence="2">
        <location>
            <begin position="28"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17335" checksum="2601BAF4212FEAFF" modified="2018-01-31" version="1">MSLHRRVFFAVFLAIISLTSSTSIALAETKESYLTLDSDGSQSFLGLVQQAEELAKDAIAQEFQNNPGLTEVTVIVTADRSRRMVPVLRSRVSRNQWQKDSRIEQWTRYFADAKYLLGFREGNISPANSGPSQTINVPAPSRPASRQNDPAFRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F535</accession>
    <name>A0A2G4F535_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56835">
        <property type="protein sequence ID" value="PHX56835"/>
        <property type="gene ID" value="CP500_003290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="10939" checksum="8DB326187DA51533" modified="2018-01-31" version="1">MNGQDARSTKEFICCGTGILPVLENKEFICCGTGILPVLENKEFICCGTGILPVLENKEFICCGTGILPVLENKEFICCGTGILPVLENCETSQLNKTNIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F548</accession>
    <name>A0A2G4F548_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56880">
        <property type="protein sequence ID" value="PHX56880"/>
        <property type="gene ID" value="CP500_003135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10546" checksum="2BED6D51C9F8C708" modified="2018-01-31" version="1">MAMATLQIQNLPDELYSRIQCLASEKNFTLNEAVIHLLKQSFESDKVMIDRAQESQLTSAILQRIRSRPRVNPRDFGLTDSTVLIREDRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F552</accession>
    <name>A0A2G4F552_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type 1 glutamine amidotransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56902">
        <property type="protein sequence ID" value="PHX56902"/>
        <property type="gene ID" value="CP500_002680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="28"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="226" mass="23772" checksum="E463B2555FCE413B" modified="2018-01-31" version="1">MTSKKVLIVLTSHDTLGDTGKETGFYLPEVTHPLDAFTQAGLTVDFVSPKGGKAPMVGVDLEDPLNKAFVEDSEQVARVENTLNPAQIDPAEYGAIFYAGGHGTMWDFADNQELAGIAAAIYEAGGVVGAVCHGPAALVNLKLSDGEYLVANKTVAAFTNEEEAAVGLTDIVPFLLEAKLIERGANFTKVASFQACVVECDRLVTGQNPASAAGVGEKMVELLKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F598</accession>
    <name>A0A2G4F598_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56905">
        <property type="protein sequence ID" value="PHX56905"/>
        <property type="gene ID" value="CP500_002695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013727333" evidence="1">
        <location>
            <begin position="29"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="143" mass="15652" checksum="013D54526D84EFBC" modified="2018-01-31" version="1">MKFRAISLFFTTCLIGIFSLAFTPPAWAITQIKLSDLSYHECPAEMAEGTVTSGSSMEATCFLITGKAKNSTNKPVVNADIFGRIYDAEDNPVMQNRTRLGSIEEVPPGVSDFQIRISVASNQPTPLKLKQFKATGFTGVVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5A5</accession>
    <name>A0A2G4F5A5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56667">
        <property type="protein sequence ID" value="PHX56667"/>
        <property type="gene ID" value="CP500_004005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="21"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="240" mass="28144" checksum="7CB761DA2B539E31" modified="2018-01-31" version="1">MQVTTAEIIYPSSDGQPMAESTIQYELIVKIKEGCESLFKHDPNVFVAADLLWYPVEGRIDISQAPDTMVIFGRPKGDRRSYIQYREDNIGPQVVFEIRSHNDTQTKMNRKVSFYQRYGVDEYYVYDPERNELEGWQRIEGILEVIEPMEGWISPRLGVRFELGEDGLEIYRPDGEKFISYAELEEERLLDRQRLQQESQRAEQESQRAEQESQRAEQESQRAQRLAAKLRELNIDPDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5H8</accession>
    <name>A0A2G4F5H8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="4 8">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_002330</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 8">
            <text>6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="4 8"/>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57044">
        <property type="protein sequence ID" value="PHX57044"/>
        <property type="gene ID" value="CP500_002330"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 8" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="9">
        <location>
            <begin position="179"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="129"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="186"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="33"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="75"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="475" mass="52025" checksum="0369A9FC8BAD7E74" modified="2018-01-31" version="1">MTKQNFGLIGLAVMGENLALNVESRGFSVAVYNRTAAKTDEFMAKRAPGKNIVATKTLAEFVEALERPRRILVMVQAGKAVDAVIDQLKPMLDPDDMIIDGGNSLYDDTERRTKDLEAAGLGFVGMGISGGEEGALNGASMMPGGTLAAYKELEPILTKIAAQVDDGPCVTFIGPGGAGHYVKMVHNGIEYGDMQLIAEAYDLLKNVGGLDGKQLQEVFAEWNTTDELNSFLIEITANIFKYIDPETKEPLVEVIMDAAGQKGTGRWTVMSALELGVSIPTIIAAVNARIMSSYKAERVRASQELTGPSGKYEGDTQEFVNKVRDALYCSKICSYAQGMALLSAASKSYNYDLDLSEISRIWKGGCIIRAGFLDKIKTAFKDDPALPNLLLAPEFKQSILDRQSAWREVLATASTLGIAVPAFSASLDYFDSYRRERLPQNLTQAQRDYFGAHTYERTDKPRGEFFHTEWTQIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5K8</accession>
    <name>A0A2G4F5K8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Cysteine synthase</fullName>
            <ecNumber evidence="4 10">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cysK</name>
        <name evidence="12" type="ORF">CP500_002250</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4 10"/>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57029">
        <property type="protein sequence ID" value="PHX57029"/>
        <property type="gene ID" value="CP500_002250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="11">
        <location>
            <begin position="8"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="8">
        <location>
            <begin position="181"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX57029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="320" mass="34019" checksum="5F50C69987CC92EB" modified="2018-01-31" version="1">MRIAHNITELVGRTPLVQLNRIPQAEGCLARIVVKLEGMNPAASVKDRIGVNMVNAAEAEGLITPGKTVLVEPTSGNTGIALAMVAAAKGYKLILTMPDTMSTERRSMLRAYGAQLELTPGVEGMTGCIRRAQEIVDKTPDAYMLQQFRNPANPQVHRETTAEEIWEDTDGEVDFLISGVGTGGTLTGISEVIRARKPGFKAIAVEPTNSHVLSGGKPGPHKIQGIGAGFVPPVLNVNAIDEIVTVSDDEAIAYGRRLAREEGLLSGISSGAALCAALKIGKRPENAGKLIVMIQPSFGERYLSTPLFQDPELNLAVAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5T6</accession>
    <name>A0A2G4F5T6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57130">
        <property type="protein sequence ID" value="PHX57130"/>
        <property type="gene ID" value="CP500_001660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="16267" checksum="00C1F19A2C18A79B" modified="2018-01-31" version="1">MTRKTRNTRQSLTASGWLKPQRWQISKIEAAEALRMPVNRIVKVYPKQHQVIVVYLNQKGQKCSSFFSYRLFARWQQETIATIASCRNQETLAPLEIIVQYDLEHFKYPVAIADAIWEALLNHIRQVIREQRHTQKCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5U3</accession>
    <name>A0A2G4F5U3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_003005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56857">
        <property type="protein sequence ID" value="PHX56857"/>
        <property type="gene ID" value="CP500_003005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="317"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="274"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="575" mass="64175" checksum="978A1CF014730C03" modified="2018-01-31" version="1">MEIMTKFLHPHSLSQRLLVSVGLSITTVGLATLGLNYRLMQSDLQTQVHNRAQSITQSLEFSTEGLLELENKSILRRVVQNFATMPGVLEIAIVDPSGMAIARSPQNATNQPYNSIYPQLAQAIDQAATTSVEVSYDIVLDGKPAIAQILPFSSTLFGTSQRRGVAIALLDLNQMKQAADRTFITSTLLLLVGIITILLIMGILLQKNVLQPLRDLNEAVSQSKKTGIFPMPKTIPANEILFLASTFEEVFRQLEIHEQLTAEIAQRKQIEVTLRDSEARERDKSQQLEQAIENLKRTQSQLIQTEKISSLGQLVAGVAHEINNPVGFIHGNLIHVQYYADSLLNLVHLYQKHYPNPIGEIEEEAENIELDFLQDDLPKILSSMRIGTDRIRQIVLSLRNFSRMDESEFKAVDIHEGIDSTLLILQHRLKARPEHPEIKVIRDYGDLPLVECYAGLLNQVFMNILANAIDALEEINTQRVACSIERHPCCITICTSVVDSQWVKIAIVDNGNGIPESIQTQIFNPFFTTKPVGKGTGMGMAISYQIITEKHGGTLRCFSTPEKGTEFEICIPVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5U9</accession>
    <name>A0A2G4F5U9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57071">
        <property type="protein sequence ID" value="PHX57071"/>
        <property type="gene ID" value="CP500_001980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="229" mass="26019" checksum="FA85D7797110D468" modified="2018-01-31" version="1">MIAQKQQPTVNGQQLTVNNNQKRVVFCDFDGTITIEETFVAMLKHFAPQLSSELMPEMYARRLSLRSGVRQLLESIPSECYGEIIDFSRPKLMRSGLVELLDFLDAKDVDFVIVSGGLRIMVETVMGDLVDRAQAIYAVDVDATGPRFQVNSPFEGDTELVSKVRVMEQYAAEEQVAIGDSITDFNMALQASSVFARDRLAEYLDEQQKPYTKWDNFFDVLENLSQKWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5X1</accession>
    <name>A0A2G4F5X1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplC</name>
        <name evidence="5" type="synonym">rpl3</name>
        <name evidence="9" type="ORF">CP500_001815</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57156">
        <property type="protein sequence ID" value="PHX57156"/>
        <property type="gene ID" value="CP500_001815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="211" mass="22514" checksum="F0F6F7CE1B0D1242" modified="2018-01-31" version="1">MSVGILGTKLGMTQVFDAEGRAIPVTVIQAGPCTVTQIKTKPTDGYSAVQIGYSEVKPKALNKPELGHLAKSGANPLRHLHEYRLEDTSSFELGQQLKADAFAPGQIVDVIGTSIGKGFAGFQKRHNFKRGPMSHGSKNHREPGSIGPGTTPGRVYPGKKMAGRMGNVQVTVRKLTIVRVDTERNLLLIKGAVPGKAGALVNVVPEKKVGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5X6</accession>
    <name>A0A2G4F5X6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exodeoxyribonuclease III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">xth</name>
        <name evidence="3" type="ORF">CP500_001625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57125">
        <property type="protein sequence ID" value="PHX57125"/>
        <property type="gene ID" value="CP500_001625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09086">
        <property type="entry name" value="ExoIII-like_AP-endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037493">
        <property type="entry name" value="ExoIII-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43250">
        <property type="entry name" value="PTHR43250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="261" mass="29443" checksum="60A52C385F546B44" modified="2018-01-31" version="1">MKIATWNVNSIRTRLEHVINWLQANPVEVLCLQETKVIDKDFPLQPFLDIGYNCYISGQKSYNGVAILSRSPLGQVSAGFAPILGDETVGSFDEQKRLITGLIDDIRIICVYVPNGSEVGCDKYEYKLYWLKLLQQYLEVALDKSPNLCICGDFNIVPGDLDIYAPKASANSAGLSVPERLALKEIIELGLNDPFRKFTSEGGHYSWWDYRAASFPRNNGWRIDHHYLSLPLYEKATNCTIDVSPRKLVKPSDHAPVIVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F697</accession>
    <name>A0A2G4F697_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57314">
        <property type="protein sequence ID" value="PHX57314"/>
        <property type="gene ID" value="CP500_000595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8729" checksum="4C82369B115E616B" modified="2018-01-31" version="1">MNYRDHITIEANKRGGKPCVRGLRITVYEVLEYLASEMTEAEILDDFPDLTREDLKACIAYAADRERRFMTATLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6C5</accession>
    <name>A0A2G4F6C5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Photosystem I reaction center subunit XII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_000765</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cellular thylakoid membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the phycobilisome linker protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57344">
        <property type="protein sequence ID" value="PHX57344"/>
        <property type="gene ID" value="CP500_000765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008213">
        <property type="entry name" value="CpcD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001297">
        <property type="entry name" value="PBS_linker_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038255">
        <property type="entry name" value="PBS_linker_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016470">
        <property type="entry name" value="Phycobilisome"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01383">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00427">
        <property type="entry name" value="PBS_linker_poly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005898">
        <property type="entry name" value="Phycobilisome_CpeC/CpcI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01094">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51441">
        <property type="entry name" value="CPCD_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51445">
        <property type="entry name" value="PBS_LINKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <feature type="domain" description="PBS-linker" evidence="9">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="CpcD-like" evidence="8">
        <location>
            <begin position="231"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="32061" checksum="6695564EBA86908F" modified="2018-01-31" version="1">MAFGPASRLGVSLFDETPPLEWVTGNSNEDLEIIIKAVYRQVFGNAYVMESERLSVPESQFKRGELTVRDFVRQMAKSELYRSRFFDSCARYRAIELNFRHLLGRPPLDLEEMRGKSTILDTQGFEAEIDSYLDSDEYQNTFGDDIVPYIRGYKTEACQSMVQFTHTFELVRGASSSSLKGNLVGKSPRLNSLVIQGTPTAVISPASSGSTFRNPLGSARTRHGAGSDENGKVYRIEVTGYRANVVNRVSKFRRSNQVYLVPFNDLSQAYQRIHKQGGVIASITVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6E6</accession>
    <name>A0A2G4F6E6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57363">
        <property type="protein sequence ID" value="PHX57363"/>
        <property type="gene ID" value="CP500_000730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="11910" checksum="ED72CCF97D1AAA13" modified="2018-01-31" version="1">MPKFTSDSKAFNPGLIWFVFFTVGFRLVGCTLPISLIFGLLGGVAIGLVVAWWHNELLLNPHKRPKDKPSDAILNKEVVETGGKYATKPRRQASTFLDWLSAPENKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6F9</accession>
    <name>A0A2G4F6F9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome b6-f complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cytochrome b6-f complex subunit PetM</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Cytochrome b6-f complex subunit VII</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">petM</name>
        <name evidence="9" type="ORF">CP500_000545</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cellular thylakoid membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PetM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57305">
        <property type="protein sequence ID" value="PHX57305"/>
        <property type="gene ID" value="CP500_000545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009512">
        <property type="term" value="C:cytochrome b6f complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00396">
        <property type="entry name" value="Cytb6_f_PetM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012595">
        <property type="entry name" value="PetM_cyt_b6/f_cplx_su7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08041">
        <property type="entry name" value="PetM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="34" mass="3528" checksum="5CD86334540845CC" modified="2018-01-31" version="1">MNPEILNAALLSFSLILVGIGGGFLLLKLQGGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6H5</accession>
    <name>A0A2G4F6H5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57393">
        <property type="protein sequence ID" value="PHX57393"/>
        <property type="gene ID" value="CP500_000175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="20"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="214" mass="24638" checksum="78B8174DB8100C48" modified="2018-01-31" version="1">MTATLIPTPQAGVLLKNISWQTYESLVNELAEQRGIRLTYDRGTLEIMTPSDPHEGNKQILGRFVETVTEELNVEIRSLGSRTCKREDLERGLEPDQCYYIENEGIVRSLKQIDLNQDPPPDLVIEIDITSSSINRMELYASLGVPELWRYDGSRLIFYQLEGQEYVEREVSPHFPFLSPSEIMGFVERQKDVGETSMIRGFRQWVRSQIHSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6J5</accession>
    <name>A0A2G4F6J5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57413">
        <property type="protein sequence ID" value="PHX57413"/>
        <property type="gene ID" value="CP500_000295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="352" mass="39248" checksum="C832198534DF2C90" modified="2018-01-31" version="1">MNQDQEKTTYSQKTERLKVIAQLIKTVTPMIWTIVLLVVILPLLGNFIISKSLTNTATTAVVVSPPHDFSKVNQDIKNAIQTAHTTAETFASKELDKWETEVIARVDNSFLDWYFDYFNQKKMEFTVPFNFLKSALLNRFDMNAASQAVSEKLTEDFQREFANRVLVPRNAQIRFQLITQDTANLYIAEVSKNVKVVQNNYNIPQVQWDKYLNDIATTISDKGNISNLSLKVLVGGSGYLVAKPLILGLATKIGSKVTAKVATKAAAKMATKTGGTVASQLGVGLIDPIVGVGIIMWDLWDYDRTVKVERPILREHLVAYLKDVKKSLLTNPETGIMAAIYQLESGILKSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6P0</accession>
    <name>A0A2G4F6P0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57361">
        <property type="protein sequence ID" value="PHX57361"/>
        <property type="gene ID" value="CP500_000615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="272" mass="30921" checksum="D56BE1B7AA396827" modified="2018-01-31" version="1">MVSVSHHRYEELYQSEPDGSVLLEDALGEILDSFQGSNRLLSQLRYVWMALTLAVVVEPTVKYYQPDSPIPEAAIKRLTHWLLKTLTEIFNPNRQLSSGIQNIENVILEDFNSFLSAQNVSSFQVLSEALDVYRNAIETLEPDRSLQALLNILDDCLEGYAIFPGSYGRRELFDWWLLDVVPSCWYLLPPVSVYSLNNVEIDDKSSPLSRLEETSSLVWSLIGAAIQKTHPTIGTLFNSKPFTSCDEEEVQINNQLLLSENKNIDSEVIKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUM5</accession>
    <name>A0A2G4EUM5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase III subunit delta</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000248">
        <property type="protein sequence ID" value="PHX53188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53188">
        <property type="protein sequence ID" value="PHX53188"/>
        <property type="gene ID" value="CP500_022840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="319" mass="35526" checksum="5ADDA44FE5A17726" modified="2018-01-31" version="1">MDYFESLIGQTQAVELLTEAVSQNRIAPGYLFVGSNGIGKSLAARCFIELLFSANLTEPRLITSVQNRVRLGNHPDLLWVEPTYMNQGKRLSPKEAEEAGLKRKSPPQIRLEQVREISNFLSRPPLESARSIVVLEQAETMGEGAANGLLKTLEEPGKAALILIAPSVDSLLPTLISRCQKIQFNRLNPAAMAEVLQQGGFGEILSNSEVMGMAQGSPGEAIGIWQQLQSMPDDLLQKVKQLPRNLRSALELAKEIDKALDTESQLWLIDYLQHCYWQQFLAGGISRSPLEPLEKARQYLLNYVQPRLVWECTLMGICQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUP7</accession>
    <name>A0A2G4EUP7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000225">
        <property type="protein sequence ID" value="PHX53272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53272">
        <property type="protein sequence ID" value="PHX53272"/>
        <property type="gene ID" value="CP500_022365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="36" mass="4142" checksum="060992C06B5D4700" modified="2018-01-31" version="1" fragment="single">MKFINPKTDYAFKKIFGSDQSQDILISFLNAIVYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUU7</accession>
    <name>A0A2G4EUU7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cyanoexosortase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">crtB</name>
        <name evidence="10" type="ORF">CP500_022215</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000219">
        <property type="protein sequence ID" value="PHX53304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53304">
        <property type="protein sequence ID" value="PHX53304"/>
        <property type="gene ID" value="CP500_022215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026492">
        <property type="entry name" value="Cyanoexo_CrtB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013426">
        <property type="entry name" value="EpsH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026392">
        <property type="entry name" value="Exo/Archaeosortase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019127">
        <property type="entry name" value="Exosortase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09721">
        <property type="entry name" value="Exosortase_EpsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02602">
        <property type="entry name" value="8TM_EpsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04156">
        <property type="entry name" value="cyanoexo_CrtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04178">
        <property type="entry name" value="exo_archaeo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="291" mass="33005" checksum="91D708FD1331957B" modified="2018-01-31" version="1">MHIQRQVRIVLKRYLLGESILTLLVLLYAPLLVHWYDGWFNKNISIEHEYFSHGLIGLPYAAYIAWTKLNSWRKLPNSLHPLGVVLLVLATLFYLSRLSDLVNLSLPLMLGSICLCLKGIHGLRLQRIPLLFVLLGSPNHIPYLIEPYALPLQHFIAQTSGLILIKAGLNVRVEEIYLYVNDQIVEVAPHCAGLKMLFTSLYVSLILLHWTGVGNSRWKSILFLASTFIISISSNILRNALLTYFHGTQKVWLFNWLHAGWGGDLYSACILGLLIIMVNGMEKYFPAQSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUV5</accession>
    <name>A0A2G4EUV5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_022165</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000217">
        <property type="protein sequence ID" value="PHX53315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53315">
        <property type="protein sequence ID" value="PHX53315"/>
        <property type="gene ID" value="CP500_022165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="13433" checksum="1F43514155E9B29B" modified="2018-01-31" version="1">MSINVVTLIGRVGGDPDVKYFESGKVKCRLTLAVRRRSRNSDEPDWFTLELWDKVAQVAADYVRKGAQIGVTGSLKFDRWQDRTTGANRSLPIIRVDQLELLGSKRDNESGMSQNNSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUY4</accession>
    <name>A0A2G4EUY4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrate ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the CmpA/NrtA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000211">
        <property type="protein sequence ID" value="PHX53344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53344">
        <property type="protein sequence ID" value="PHX53344"/>
        <property type="gene ID" value="CP500_021990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13553">
        <property type="entry name" value="PBP2_NrtA_CpmA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044527">
        <property type="entry name" value="NrtA/CpmA_ABC-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013754096" evidence="4">
        <location>
            <begin position="24"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="440" mass="47285" checksum="4E72B0CC222A0FDE" modified="2018-01-31" version="1">MSNLSRRKFIIAAGTTAAGTLLAHGCSSGSNNTSSSPSPSGSSASPTPAVNISPGDAPEVTTAKLGFIALTDSAPLIIAQEKGLFAKYGMKDVQVTKQASWPVTRDNLELGSDKGGIDGAHILSPMPYQMTLGTITKGNQPVPMNIVARLNTNGQAISLSKKYLDLKVGTDSAPLKAALANQKIAITFPGGTHDLWMRYWLAAGGIDPNTDVSVIPVPPPQMVANMKSGSMEAFCVGEPWPAQLVTQKVGYTALVTGELWKDHPEKALTLRADWVEKNPKAAKAITMAVLEAQQWCDKPENKDEMCNIISQDKWLKVPVADIIGRAKGQIDYGTGRVEAASPLLMKFWADNASYPYKSHDAWFITENIRWGYMPATTDIKATVDKVNREDIWKAAATAIGVPAAQIPATTSRGVETFFDGVKFDPEKPEEYLKGLVIKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV01</accession>
    <name>A0A2G4EV01_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphopantetheine-protein transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000228">
        <property type="protein sequence ID" value="PHX53260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53260">
        <property type="protein sequence ID" value="PHX53260"/>
        <property type="gene ID" value="CP500_022465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="2">
        <location>
            <begin position="127"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="251" mass="28925" checksum="CCB0516186ED13EB" modified="2018-01-31" version="1">MNTNIIEWKIPPKDLILNSDEVHVWRVDLEMRASCLQSLQESLSTDELKRAERFYFQKDRAHFIAARGILRKILGCYLNKNPNELRFSYNPYGKPSLVTAVSEYKLCFNLSHSHGIALIAVEQNREVGIDIERIRKDFPYQQIAESFFSPFENAVLRSLPEHQQLRAFFTCWTRKEAYIKAVGKGLSIPLNGFDVAIAPGEPAALLNFLENPKEVSRWSLIELIPGLDMVATLAVEGDRFKILCWQWQYSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV73</accession>
    <name>A0A2G4EV73_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000198">
        <property type="protein sequence ID" value="PHX53431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53431">
        <property type="protein sequence ID" value="PHX53431"/>
        <property type="gene ID" value="CP500_021550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="220"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="409" mass="45826" checksum="8C8C06FB8EA246FB" modified="2018-01-31" version="1">MKVLLSAFACEPNLGSEEGVGWNTVLQVAKYHETWVFTRTFCRSYIEAELKLHPVPNLHFVYFDPFGWSEDWKGKQGLLQLHYYLWQIWAYFMARKLDRAIGFDIVQHVTYVKHWSPSFLALLPHPFIWGPVGGAEAAPKPFWADFSRRGKIYETLRELAQGLGERDPFVGLTARRSVVALATTEETAARLRFLKAPNVKIFSQVGLSQTEIQQLEQSPTPPTEIIRFISVGRLLHWKGVHLGLRGFAEAKLEQSEYWIVGDGPERERLEALATELGLTKQVHFWGALPRAETLSKMGESHVLLHPSLHDSGGFVCTEMMGIGRPVICLDLGGPATQVTAETGIKVPAIDPDRAVQGLAEAIVCLAGDPELRSGLGQAGKKRLKEVYDWDVKGTFFAQLYESIVDRKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVC3</accession>
    <name>A0A2G4EVC3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="6">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">lysS</name>
        <name evidence="10" type="ORF">CP500_021565</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6 7">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000199">
        <property type="protein sequence ID" value="PHX53428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53428">
        <property type="protein sequence ID" value="PHX53428"/>
        <property type="gene ID" value="CP500_021565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="180"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="519" mass="58469" checksum="2858ADE9D12013E2" modified="2018-01-31" version="1">MTLSEAEVRSQKVDELRSQGIEPYPSQSYVRSHTTKQVREIFSQPGKELQNGESDPEEISLRVGGRITSKRDSGSICFIDLKDATDKIQLKIEKKVVTGEVGLSFQQIKKLLDVGDFVGVEGIGCRTQKGELSISVREFTLLSKATIQFPDAYYGVSDPEVCRRHREMDLASNQDALNRFMLRSRIVQSIRSYLWNANFYEIETPTLQAIYGGAAAKPFVTHHNALDVDLYLRVAPELFLKRAICGGFERVFELGKAFRNEGIDSTHNPEFTSVEVYQSYADYFDILAVVEDVMCCAAQAVLGDVKEVDNQGQMISLERKFDYSEKYPSFSGQHWEVKTMVEAVRDEFGLDFDSLDLESAIASATKLELHLSKLEKQSLGYVLYAVFDKLVVPKLIQPTFIIDFPVEVSPLAKGHRSKPGFVERFELFINGMEYSNGFSELNDPKEQRKRFEEQLAQKDAGDDEAHPMDEDFIQALSLGMPNCAGMGIGVDRLVMLLTNTQSIRDAVMFPTMRPVKASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVK8</accession>
    <name>A0A2G4EVK8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein Thf1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">thf1</name>
        <name evidence="4" type="ORF">CP500_020815</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in photosynthetic membrane biogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000177">
        <property type="protein sequence ID" value="PHX53565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53565">
        <property type="protein sequence ID" value="PHX53565"/>
        <property type="gene ID" value="CP500_020815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01843">
        <property type="entry name" value="Thf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017499">
        <property type="entry name" value="Thf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34793">
        <property type="entry name" value="PTHR34793"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11264">
        <property type="entry name" value="ThylakoidFormat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03060">
        <property type="entry name" value="PS_II_psb29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="27096" checksum="08AC4850A0AA3E81" modified="2018-01-31" version="1">MNKNRTVSDTKRSFYTIHTRPINSIYRRVVEELMVEMHLLSANADFQYDSIYALGVVTAFNRFMLGYLPEKDQDSIFNGLCKSIESDPDRYKQDAHRLEALADRLSGTELLSWLDRSTSFDDTGDLQGSLEAIANNPQFKYSRLFAIGLFSLLEKADPSLVKDEETLNNTLKTVSAALHLPEDKVSKDLDLYRSNLEKMAQARIVLEDVIQAERKKREKRDLANQASASSSVDSTESSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVP8</accession>
    <name>A0A2G4EVP8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000179">
        <property type="protein sequence ID" value="PHX53548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53548">
        <property type="protein sequence ID" value="PHX53548"/>
        <property type="gene ID" value="CP500_020885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15626" checksum="97D16E31A0489890" modified="2018-01-31" version="1">MERGLMWLPLLAIFIGLAWAGWNEYKKLEAYGVWAQKFDRAKYDIYAVLGQQEDNLTWGKPTRSGPVNLQTFSLKDVESLELMVNGAAVDLENPPSAGSAIVLEFVLKDAEAVQVPFTEIPLATKWCQHLQQELQRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVR8</accession>
    <name>A0A2G4EVR8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_020865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000178">
        <property type="protein sequence ID" value="PHX53556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53556">
        <property type="protein sequence ID" value="PHX53556"/>
        <property type="gene ID" value="CP500_020865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013888678" evidence="2">
        <location>
            <begin position="23"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="30"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="300" mass="33767" checksum="015FDE9AC8F0538B" modified="2018-01-31" version="1">MRISKNDFFFYSCWLLSLFAVAGCTSSSEKRVVICSKDFTEQVILAEMLARHIEAKTDIKVERELNLGGSLCHQSLTTGKIDLYVEYTGTAYANILKQKPISDPKKVFNYIKQEYPKQFQAEWMEPLGFNNGFAIIVRGDDAKKLNLQTLSQLGKAAPKLRAGFGPEFKEREDGFPGLAKTYGMKFAEEPKELLLGLLYQALQQKEVDVIAGGTTDGLIQSLGLVVLQDDKNYFPPYEAVPVVRSQILEKYPELRAVIAELGGKISEDDMRKMNYQVDKKQEEPGQVAQQFLQQKLGNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVX0</accession>
    <name>A0A2G4EVX0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2281 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53596">
        <property type="protein sequence ID" value="PHX53596"/>
        <property type="gene ID" value="CP500_020705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018739">
        <property type="entry name" value="DUF2281"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10047">
        <property type="entry name" value="DUF2281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2281" evidence="1">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8110" checksum="AB720A2BB09104F5" modified="2018-01-31" version="1">MIQPVILEKLAELPESLQTEVLHYIEFLIEKQAKNSTQEKPTKKRRVAGTMKGMFVLPLPDDFDEPLRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWH4</accession>
    <name>A0A2G4EWH4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5 7">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsL</name>
        <name evidence="5" type="synonym">rps12</name>
        <name evidence="9" type="ORF">CP500_021085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 5 7">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000184">
        <property type="protein sequence ID" value="PHX53527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53527">
        <property type="protein sequence ID" value="PHX53527"/>
        <property type="gene ID" value="CP500_021085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="14092" checksum="DC21FF1EAD299936" modified="2018-01-31" version="1">MPTIQQLIRSAREQTQKKTKSPALKSCPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGTLDTAGVKDRKQGRSKYGAKRPKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWJ7</accession>
    <name>A0A2G4EWJ7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbfA</name>
        <name evidence="3" type="ORF">CP500_019535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RbfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53810">
        <property type="protein sequence ID" value="PHX53810"/>
        <property type="gene ID" value="CP500_019535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="142" mass="15955" checksum="3A0F925A6B7D7C29" modified="2018-01-31" version="1">MATSRRIERVASMIKREVSLMLLNGIKDDRVGAGMVSVTEVVVSGDLQHTKIFVSIYGTDEAKAETMEGLKSATSYVRNQLGQRLQLRRTPGVAFLEDRSLERGDKMLILLNQLSVDRKPDILDNEELTDDDRDDDLEADED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWW8</accession>
    <name>A0A2G4EWW8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54019">
        <property type="protein sequence ID" value="PHX54019"/>
        <property type="gene ID" value="CP500_018465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="645" mass="71594" checksum="716D2595BB263527" modified="2018-01-31" version="1">MEHKINPSTNRPKPPENPKVPSTRRRRQARRTQNPQHSQPKTPRFATPNQPTPTSVPRYPWKRLIANLTALTILCGFAALMGGGAWLSYQLIVDPNGNKWITKFVPEWSRLPLATRDSIQTLDQIQASIRKLGFVTGEPLPLPIHQSGDNSVSDLLLPIMVERTVNASTACKNPCRQIVELRVYKRVQIPDRDSDTVQYFQLASSVNVEGPAESFVLASLADSKSDNQGSNQSLPLTELHRFNGKAPQSGIWFNVSGQLVRGDKKIPYGQVVRYNPSQNHLISLLEWVSAAGQAPNWQQIVKGSNPQLAIDQTVGLEPQFTIYQIGSRKFVPNPVQLNAISLEEFALNDETYKNGLRLAKSGLWSPALNVMRTAKGKAAGNWPTVAQAQLDAIEFHAKITKAQAIASWASPGQQVLAELIDGRWSQALQVFEADPSNSSEIAKTLKNDDGKLLNRVDAALRINSQDGDIKAWGALIVAAQNGTREAMNWLDQQSDTDSETRNRIRNLVNKLDEAVSLAESLEKHKSQITGSATLVSSINPNEWIEPEAKNDLKLTEQQVWYQVQVASFYDGKRWVNSPFLDMELRSFSATQVKWLWGRLGLLADPNIKIEVAMNNGQQRVALGTVKAVQLQDGSLRLLAAVDKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX64</accession>
    <name>A0A2G4EX64_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000158">
        <property type="protein sequence ID" value="PHX53737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53737">
        <property type="protein sequence ID" value="PHX53737"/>
        <property type="gene ID" value="CP500_019830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="159" mass="18485" checksum="43322CA4895EE28C" modified="2018-01-31" version="1">MAREPISTWYFTLVVVHLENRFLLVQERKYDQQWYLPAGRVEKGESLLEAALRNTVEEGGISVIIEGILRVEHTVMPRGNVRLRVIFVARPEDKTPPKSKPDEHTLCAGWYSLKELDQLSLRGEEVREIFDYMASGAPIYPIDLLSQEGAPFKMHRYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX86</accession>
    <name>A0A2G4EX86_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anthranilate synthase component I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54086">
        <property type="protein sequence ID" value="PHX54086"/>
        <property type="gene ID" value="CP500_017980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010118">
        <property type="entry name" value="Para-NH2Bz/anthranilate_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01824">
        <property type="entry name" value="PabB-clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="2">
        <location>
            <begin position="45"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="208"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="482" mass="53957" checksum="A77C4910142B1ECB" modified="2018-01-31" version="1">MKSIKPWHWRKLPLNKRSGSEIFQALFLSKTDNNKASISGFSSQDMAVLLESPVTSATNLTRYSICAGSPRIIDGQSQLWTPPVGEILPFLRNILHHQKQNLELNVPPSIPFTGGWLGWLGYDLAWEIEQLPQINTDPLPFPVSCWYEPASFAVLDHQEQSLWLAASQSSQLDVMQHQLELIKREIAHKNLAKNSQDNAASCNLQLSQNEYEKIVEKAQKYIYAGDIFQANLSVRFEASTDCDSWSIYRALQQINPSPFASYWQTPWGDIVSCSPERLVQLLGNKVDTRPIAGTRPRGLTSIQDDQLAEDLVENVKEIAEHIMLVDLERNDIGRVCEWGSVQVNEFLTVERYSHVMHLVSNVIGKLRVDCDAIDLIRAVFPGGTITGCPKVRCLEIIEELEPVKRSLFYGSCGYLDWRGNLDLNILIRTLLYAPKSDGSSGGIVWGQVGAGIVADSDPEREWLESLQKAQAQISALGLAISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXA0</accession>
    <name>A0A2G4EXA0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000119">
        <property type="protein sequence ID" value="PHX54163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54163">
        <property type="protein sequence ID" value="PHX54163"/>
        <property type="gene ID" value="CP500_017565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="104"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="336" mass="37555" checksum="E5AECB93C7577374" modified="2018-01-31" version="1">MSNALVQNHPYPLLVVIVNYRTPGLTIDCLRSLVSEVESLPGMRVAVSDNASGDGSVAEISSAIVAERWNEWASFVPLDCNGGFAFGNNALIRPVLQSPNPPPYILLLNPDTVVRPGALKSLVDFMDTHPEAGIAGSRLEDPDGTPQESAFRFHSLLTELDFGWRTGFISKLLKNWAVAPPISQETCQTDWVAGASMIVRREVFEKIGLMDEAYFMYCEEMDFCLQAHKAGWSCWYVPESRVVHLVGQSSGVTDTKKPAKRLPTYWFDSRRRYFLKNYGLFYTALTDVCWASGFAAWRVRRVLQGKPDGDPPKLLSDFVLNSVFFKGGKIEKIKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXA3</accession>
    <name>A0A2G4EXA3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroorotase</fullName>
            <ecNumber evidence="2">3.5.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53777">
        <property type="protein sequence ID" value="PHX53777"/>
        <property type="gene ID" value="CP500_019705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01317">
        <property type="entry name" value="DHOase_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004722">
        <property type="entry name" value="DHOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="271"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="428" mass="45766" checksum="7C9E5E04A1CF811F" modified="2018-01-31" version="1">MTSELLQNVRVLDPVSQGDRIADVLITEGHIKAVEPKIAEFPPDTQIRDCRGLILGPGLTDMYSHSGEPGFEDRETLQSLMQAAAAGGFTRVAILPDTSPPIDNLAGLAFFQQHIRNFSPSLPRLYFWGALTAGVQGQQMAELAELADHPIVGFADGSPLANPALAMRLLEYIQPLGKSVALWPCDRTLAEKGVAREGAVSLRLGLPGIPAAAETSALAAMLELVATVGTPVHIMRVSCARSVELIRDAKARGLPVQASVTWMHLLLNVGAISGNTTVSFPYDPNLRLDPPLGNEADQLALIQGLKDGVIDAIAIDHSPHTYEDKTVAFADAPPGAIGLELALPLLWQQLVETGEFSALELWRVLSTSPAICLGQTPATAVPGVSAELILFDPQMSWTVDGQSLKSRSANTPWFGKQLAGKVLQTWTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXA8</accession>
    <name>A0A2G4EXA8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone deacetylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000119">
        <property type="protein sequence ID" value="PHX54161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54161">
        <property type="protein sequence ID" value="PHX54161"/>
        <property type="gene ID" value="CP500_017555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016575">
        <property type="term" value="P:histone deacetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09993">
        <property type="entry name" value="HDAC_classIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044150">
        <property type="entry name" value="HDAC_classIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="His_deacetylse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="2">
        <location>
            <begin position="25"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="305" mass="33489" checksum="BDD8FBCA1C852C9E" modified="2018-01-31" version="1">MDLPIIYHEDYVAPLPSGHRFPMAKFRLLYEMLLADGVASHAQFHAPELPPSEWIQLVHDDSYIQAYCNGTLDAKAQRRIGLPWSPALVNRTCIASSGTVLTAKLALEYGLACNTAGGTHHAFPNYGSGFCIFNDLAIASRVLQQLGLVRQVLIVDLDVHQGDGTAVIFQDDDSVFTFSMHCEVNFPGTKQKGDLDVALPVGMEDEEYLQTLAKYLADLLSDVKPDLVLYDAGVDPHQADKLGKLALSDTGLFRREMQVLSTCLAGGYPVACVIGGGYSDDTKGLVYRHSLLHRAASQVYRQYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY13</accession>
    <name>A0A2G4EY13_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CopG family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54368">
        <property type="protein sequence ID" value="PHX54368"/>
        <property type="gene ID" value="CP500_016570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="46" mass="5618" checksum="8AFB2E62EBA0F86C" modified="2018-01-31" version="1">MKKRLDFRIEEYEFQILEDYCELVGRTKTDVLRELIRGLKTKKKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY31</accession>
    <name>A0A2G4EY31_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_016060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54445">
        <property type="protein sequence ID" value="PHX54445"/>
        <property type="gene ID" value="CP500_016060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="5">
        <location>
            <begin position="455"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="719" mass="79878" checksum="FCAD78FCCB0F325B" modified="2018-01-31" version="1">MLLCPHCQFENPNQNKFCQQCGNSLIYKSCHQCGTQVGVSTKECQNCGTATGQVWQAIICGRSNLPAVGADELPQKPDIVPESAPIAHSTQAEPIDDPFHSPEIDDMAVVSAIDPESFQTNQTSTTTPPDSQITLSQSNFTTAPEPETSPEIADIPPQSPEFPVPNSQDLIPSQPAGTYLDSQQRYQLLETLPPRKPSDTVAVPVLDCQPLQMSPLKALLAANSASVAKRAEPGENLTDSALAQLCPGIAEPYLALGWEFSHNLPVIHDSWSENEQAVLLLEDFSHWSPLVERWSQPETSTQQILYWLHEMTELWAALEPWGCRQSLLELTNLRVNPDSFSSLASLRLQRLYPEPPDSNLQLIDLGQLWQTIFNQSDRTQFGALLELLQQMYRGEIHTIDELRSRLETFPLELQPALAEITTQTRLQFSNPDQPSLDLGEVLTQPMPVQMYRLEDAGITDVGLQRAHNEDFFSIWTQINKLETSFGRTFQTKGLYILCDGMGGHDSGEVASQLAAETLKEFFQTNWENQLPSSDTIREGVLLSNKAIFEINQKESRSGSGRMGTTLVTVLVQDTQVAVAHVGDSRLYRLIKGQTLEKITTDHEVGQREIKRGVDPETAYSRPDAYQLTQAVGPRDSNFLKPDVLFLELCEDTLLILASDGLTDNNLLETHWQTCLEPLLQPQADLEQGVAKLIELGNKHNGHDNITAIVIRAQVGASRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY40</accession>
    <name>A0A2G4EY40_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54431">
        <property type="protein sequence ID" value="PHX54431"/>
        <property type="gene ID" value="CP500_016235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="186"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="687" mass="76984" checksum="476B631CC02DAC6E" modified="2018-01-31" version="1">MNVKTVSPTSTQTYANSGTQAVLENLKDVNTIPVQAVPLETEAVTSEVLKSAKDRAFELAGDAVRYDPVAIAAEYRNRPLQVWGRMLSVFWTFFSFTFSLWFDGKTGRVAKNEKRRAARLRDILAQLGPAFIKIGQALSTRPDLVPPVYLEELTTLQDQLPAFPNEVAYQFIQEELGAHPNEIYAEISPDPIAAASLGQVYKGKLKTGETVAIKVQRPGLAENIGLDIYILRRVALWAQNTFKIIRSDLAAIMDELGERIYEEMDYTHEGQNAERFAELYGHIKDIYVPSIYWEYTRRRVLTMEWITGVKLTNLEAVKAQGIDAPYLIEVGVQCSLRQLLEHGFFHADPHPGNLLATPDGQLAYLDFGMMSEVKPYQRYGLLEAIVHLVNRDFEGLAKDYVKLDFLTPDTDLTPIIPALAGVFNNALGASVAELNFKSITDELSAVMYEYPFRVPAYYALIIRSLVTLEGIAINVDPEFKVLSKAYPYVAKRLLSDPSPELRTSLQELLFKQGEFRWNRLENLLSNARDSEDYDISKILNQALDYLFSERGDFIRDRIVLELVKGLDTLSSNAFANAKSVVGEWFGVKASQPVVSQTAQNNLAHIKRIWDILQSTPGFDGTKVLQLLPQLLVKPELQNMGQRVVGGLAQRAVARLIREFLLSSEPEVISNNGSYPKTSPQLSLPAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYA4</accession>
    <name>A0A2G4EYA4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54513">
        <property type="protein sequence ID" value="PHX54513"/>
        <property type="gene ID" value="CP500_015720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013720549" evidence="1">
        <location>
            <begin position="22"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="16676" checksum="8F5FA218F19D9D3C" modified="2018-01-31" version="1">MLKFSAVCVLAFVLVISGANLNNAIARDSESRTQAVDRFTDWFFYKVNPQLGDRKLRSDDSSVYIREWNAIRSTVDREMITTPGDCVGDAFWDFDYRSHGRSLDRIADTIWAIRDPSGDKTRADVSQKERNKLRESIIREHFCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYD5</accession>
    <name>A0A2G4EYD5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54470">
        <property type="protein sequence ID" value="PHX54470"/>
        <property type="gene ID" value="CP500_015915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039554">
        <property type="entry name" value="HigA2-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13744">
        <property type="entry name" value="HTH_37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="34"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="117" mass="13591" checksum="C49BAEA812F3CAA8" modified="2018-01-31" version="1">MTISLKTVMDNLPPDQRAIVEKRSVELMTEEMTLQDLRKARKFTQIRMAELLNMRQKNVSRLERRADLLVSTLQIYIAAMGGELSFVVEFKDRPPVKITGLTSMFEESSYTNEDEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYL0</accession>
    <name>A0A2G4EYL0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid oxidation protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54615">
        <property type="protein sequence ID" value="PHX54615"/>
        <property type="gene ID" value="CP500_015160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15742" checksum="218377A4A78399C6" modified="2018-01-31" version="1">MSAKDKFHDVVKIALQKDGWQITDDPLSISVGGVDMLIDLGAERLLAAEREGEKIAVEIKSFLNTSAITDFHLAVGQFINYRTALKFKDPQRQLFLAIPLTAYNDFFKREFAIAVVDDYQFKLLVYDVEEEVIALWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYL5</accession>
    <name>A0A2G4EYL5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54568">
        <property type="protein sequence ID" value="PHX54568"/>
        <property type="gene ID" value="CP500_015400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="10280" checksum="2A6D70620FF1BE6D" modified="2018-01-31" version="1">MAFLGCEARSLFGDRETAIALLSPHILLKLVVFLHHFFSQNRRALIMENLLIVNHFIPKSATRLTAGLASTAMRRILCIYFSQIRAIAPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYW0</accession>
    <name>A0A2G4EYW0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA/RhaT family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54703">
        <property type="protein sequence ID" value="PHX54703"/>
        <property type="gene ID" value="CP500_014695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="54"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="209"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="351" mass="38323" checksum="551FD388606F5109" modified="2018-01-31" version="1">MSKRVELPENDIDKQEEELAVHDLITTLKVQPKSSMILANQDDLASTDNRGNFWAIVWLSAALLAVSFAAIFIRLSEREIGPNATIFNRLWIATVVFAVWDAVDAVRRRMSGNALEVRSNYTLGDVMLLTAVGIVSSASLGFWAWSLTQTNVANSTVLRNLTPLFTTLGGWLLLGRRFDNNFLLGMTVALVGAIAIGIDDLQTAGDNLAGDIAALFSAMFYAGNLLIAEHLRTKFPATTILMWRCFIGSLLILPLVLLAGDRIFPYSWQGWLAVIGLAVICQAFGQGLLIHSLGRLSSGFVAIFLLLEPVITAILAWILFSESLSLFNWLAFAVVLTGIYLAKSSGNADKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYW6</accession>
    <name>A0A2G4EYW6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54678">
        <property type="protein sequence ID" value="PHX54678"/>
        <property type="gene ID" value="CP500_014745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013579223" evidence="2">
        <location>
            <begin position="21"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="291" mass="31783" checksum="9466EC47699582AA" modified="2018-01-31" version="1">MLRKLIVYLMAITLCLTTIACGSSTPTPEANQKVNTVRSAPTPISNNLTQGQYPVQQATYDDSEGEYSLMLLNTPAGTSSVYRSRDLQMARLTDEEISQGKKSYLSLEQSKASLHLTEDFKIEYVHNVTETVSNPQTGQPQTVVVRQQSGFWAPFAGAIAGQAIGSLLFTPRYYMPPVYQPGIMRGYGGYGNTYGEAVSQYQTRYQAPPAAVRNRQALRTTGRLRSPTSNAPATRQVPPNANRSTGSGYGGSNLRRSQKPSSPQQRRSPSFGSGGNSRPPSRSPSFGSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYY1</accession>
    <name>A0A2G4EYY1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Argininosuccinate lyase</fullName>
            <shortName evidence="5">ASAL</shortName>
            <ecNumber evidence="3 5">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">argH</name>
        <name evidence="8" type="ORF">CP500_014415</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="3 5"/>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54733">
        <property type="protein sequence ID" value="PHX54733"/>
        <property type="gene ID" value="CP500_014415"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="11"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C2" evidence="7">
        <location>
            <begin position="367"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="461" mass="51208" checksum="84381F078636F8AA" modified="2018-01-31" version="1">MTKQQTWSQRFESALHPAIVRFNASIGFDIELIEYDLSGSVAHAKMLAKTGIISDAEGEQLVNGLEQIRLEYQEGLFVPGIDSEDVHFAVEKRLTEIVGDAGKKLHTARSRNDQAGTDTRLYLRQKIAEIRDQLREFQGVLLDIAEPNVETLIPGYTHLQRAQPISLAHYLLAYFEMSDRDWERLGDVSKRVNISPLGCSALAGTTFPIDRHYTAELLHFDKVYANSLDGVSDRDFAIEFLAAASLIMVHLSRLSEEMILWSSHEFGFITLKDSCATGSSIMPQKKNPDVPELVRGKAGRVFGHLQAMLVVMKGLPLAYNKDLQEDKEALFDGVKTVQACLEAMTILLREGIAFQGDRLAAAVTEDFSNATDVADYLATKGVPFREAYNLVGKVVKTCLLGGKLLKDLTLEEWKELHPAFETDIYGAIAPQQVVAARNSYGGTGFDRVRKSLIAARDRLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ57</accession>
    <name>A0A2G4EZ57_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zn-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_014340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54758">
        <property type="protein sequence ID" value="PHX54758"/>
        <property type="gene ID" value="CP500_014340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="PTHR32494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001235">
        <property type="entry name" value="Amidase_carbamoylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001235-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001235-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="413" mass="44317" checksum="7E116A9D7A468AD6" modified="2018-01-31" version="1">MTLTLTLAVNGARLNRSISQLAQIGKLPGGGVSRVAFTSSDLLARQLVESWMVEAGMTVRIDAAGNIIGRYPGKREGAALATGSHIDTVPVGGHYDGVLGILAGIEVVRVLHENNLCLEHPIETIVFTDEENTVIGCKAMAGNTVSNPEYYQRSDGTSIETCLAQIGGDWSKIAEAKRHPQEIAAFVELHVEQGGVLENTGDEIGIVQGIVGQYRYAVTVMGRPNHAGSTPMCDRKDALVAAAQMVLAVNKLGVETPGEQVATVGYLNVSPNATNIVPGKVDFKIDLRDISQIHLEELLVKMKQEFAAIAAATKTEVEMTEMLHVLPTLAAPKIQNAIAEVCRELSLTSTHLISRAGHDAQEIGRFADMGMIFVASRGGISHAEDEYTSPEQCTQGANVLLQTFLKFDRLYGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZR8</accession>
    <name>A0A2G4EZR8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_013035</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55001">
        <property type="protein sequence ID" value="PHX55001"/>
        <property type="gene ID" value="CP500_013035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="13">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="11">
        <location>
            <begin position="159"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="12">
        <location>
            <begin position="285"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX55001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="391" mass="44419" checksum="B74B6E3CEB5942A5" modified="2018-01-31" version="1">MLKAFNYRIYPTSEQSILLAKSFGCARWFYNYALNLTSETYKQTGKGLSRNEIINLLPSLKKEYEWLTEAPSQALQQAALNLSSAFLNFFEGRAKYPNFKKKQNRQSIRFPQGCKLKDDTLKLPKIGDVHCQVSRQPEGTLKSVTVSVDPSGEYFVACLYDDGKDLPEKSSEGKAIGIDVGLTHYAITSDGTKHGNPKYYRKYEKKLAKRQKQLSRKLKGSNNRHKARIKVAKVHAKIVRCREDFLHKLSRKLVDENQVIVVENLAVRNMVKNHKLAKSISDAGWGQFCTMLKYKSEWAGKTYIEVDRFYPSSKTCNNCLNRVDSLSLDIRSWQCLKCGENHDRDINAAQNIRDEGLRILAVGHTVTASGGRVRPSKGTAFTRHLPVNEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZT8</accession>
    <name>A0A2G4EZT8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-protecting protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dprA</name>
        <name evidence="3" type="ORF">CP500_014680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54707">
        <property type="protein sequence ID" value="PHX54707"/>
        <property type="gene ID" value="CP500_014680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041614">
        <property type="entry name" value="DprA_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17782">
        <property type="entry name" value="DprA_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DprA_WH" evidence="2">
        <location>
            <begin position="318"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="383" mass="42317" checksum="362F1C4C0AA62822" modified="2018-01-31" version="1">MVEERAYWLAWSQINGIGPILLQRLHEHFNSLATAWTAKSIDLCQVEGFGKQTIEKTLQERDKINPEEFIEKHLIKNPLFWTPADRDYPRLLLEIPSPPPVLYYRGTVDTKENQGITPTVAIVGTRSPSEYGRRWTRKFSSALAKSGFTVVSGLATGIDTEAHTSCLDAGGRTLAIFGTGVDVVYPRPNERLCDRILQQGLAISEYPAGTQPNKTNFPRRNRIIAGLSRATIVIEAPHKSGALITAYEANDFCRDVYVLTARLDDELSFGCMELLSKGAHPILPGNDRMLSEERLLEMLGAIPKLDRAEQLSLFPVNPAPPKRMPPLDAQLALVLSAIVSEPISFDSIVEAAGLEAGIVSSTLLQLELLGLVSQLPGMRYQRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0A0</accession>
    <name>A0A2G4F0A0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bicarbonate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the CmpA/NrtA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55168">
        <property type="protein sequence ID" value="PHX55168"/>
        <property type="gene ID" value="CP500_012355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13553">
        <property type="entry name" value="PBP2_NrtA_CpmA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044527">
        <property type="entry name" value="NrtA/CpmA_ABC-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="461" mass="49972" checksum="7782A4079C1C834E" modified="2018-01-31" version="1">MTKFSDQFSRRKFIVTAGASAVSSILLKGCLGNPPEPGATDAAGGEIPAGTSPVAVPNEKRVEGIESTKITLGYIPIVEAAPLIIAQEKGFFAKYGMTDVKVAKQANWGSARDNVEIGSAGGGIDGGQWQMPMPYLISKGLITKNKAGIPMYVLAQLNTQGNGIAIASKHEGKGLGLKLDKAAQDYILGLKKAGTPFKAAYTFPKVNQDLWLRYWLAANNINPDADVELLTVPAAQTVANMKTGSMDGFSTGDPWPLRIVKEKIGFMSALTAEMWKGHPEEYLAIRGDWVDKHPKATEALLAGLIEAQQWCDKPEHRAELVAIVSGKGFFDVPSEVLTPSYEGKYVMGDSKPDINDFKMGPLYWNDGVGNVSYPYASHDLWFLTESIRWGFLPTKTLADKKTLIGKVNRADIWKKAAKLAGVADADIPKSTSRGIEKFFDGTEFNPDKPEAYLKSLAIKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0C2</accession>
    <name>A0A2G4F0C2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55211">
        <property type="protein sequence ID" value="PHX55211"/>
        <property type="gene ID" value="CP500_011975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="203" mass="21690" checksum="A10079501EF323AA" modified="2018-01-31" version="1">MNEKENQNEVASEVASKVKSTLNDAIQGLKIFLINPVGGLPVFFQGLGKERALGVGIAFGIAYVICFVFACQKFLTQFSGNSSLFNLILASTANFLSIAGASFLTRKLFRGYGSFQGDIFIAGVALVPASLLLLISSLLGITNVEIIVIVMVVAITYTILMIYTGCHKISGIPENAAAFAVSVMLLLSGWLFKILILSNILQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0I6</accession>
    <name>A0A2G4F0I6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55272">
        <property type="protein sequence ID" value="PHX55272"/>
        <property type="gene ID" value="CP500_011535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="27"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="220" mass="24982" checksum="B15D0B302D73D670" modified="2018-01-31" version="1">MVTTTSTPVEQQVTPENRVVLKGVSWSTFKALVADVGDDRAWRIAYDRGVLEIRMPLLEHEVPKGLIESFIEATADELEIEVMKAGSLTLEREDLTRAVEPDSCFYIQNEASVRGKRNINLPEDLPPDLAIESDYTNSSVNKDAIYAAIGVPELWRYQRQSLQVYHLVEGKYQKCDRSLAFPFLPVAEIPGFIEQSRTIGQRSAVRLFRQRIREILLSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0J7</accession>
    <name>A0A2G4F0J7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55282">
        <property type="protein sequence ID" value="PHX55282"/>
        <property type="gene ID" value="CP500_011590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="39"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="19320" checksum="1B06F5661842A049" modified="2018-01-31" version="1">MTSSDEMFAEAANNWDLERLYKAMAEAKWQVSPRARKGLTEREKLFLRGLLCGHSPAEIASQLHQSRKGVEVYISKTLYQYFKKITDVPNEKVSNWRNIHNSLEEAGYKTTPSVKSHSSNYSPQVPLVNIVNISLNNQSHSITIDIHLQLTLPSLSQTTMTEDMDGKDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0K2</accession>
    <name>A0A2G4F0K2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C</fullName>
            <shortName evidence="1">Asp/Glu-ADT subunit C</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gatC</name>
        <name evidence="2" type="ORF">CP500_011635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55291">
        <property type="protein sequence ID" value="PHX55291"/>
        <property type="gene ID" value="CP500_011635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00122">
        <property type="entry name" value="GatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003837">
        <property type="entry name" value="Asp/Glu-ADT_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036113">
        <property type="entry name" value="Asp/Glu-ADT_sf_sub_c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15004">
        <property type="entry name" value="PTHR15004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02686">
        <property type="entry name" value="Glu-tRNAGln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141000">
        <property type="entry name" value="SSF141000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00135">
        <property type="entry name" value="gatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="93" mass="10618" checksum="276E34D00ACF8BDA" modified="2018-01-31" version="1">MIDKEEVRKVAKLARLELTPEEEEQFTGQLNGILDYFEQLSELDTSKVKPTTRAIDVSNVMRSDDLQPFADRESILAGSPDRDGEFFKVPKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0R4</accession>
    <name>A0A2G4F0R4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55350">
        <property type="protein sequence ID" value="PHX55350"/>
        <property type="gene ID" value="CP500_011160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7493" checksum="B3B25E73A302B01B" modified="2018-01-31" version="1">MRIKLFNQDSSLLNQVEVSAHTCLISLGARNPIASKLKRMAIAPKSNSKAIALNSTQVGPTNPTLQKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0V3</accession>
    <name>A0A2G4F0V3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_012705</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55077">
        <property type="protein sequence ID" value="PHX55077"/>
        <property type="gene ID" value="CP500_012705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="615"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="656"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="737"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="778"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="474"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="848" mass="94429" checksum="EC8CFE7829F70CA1" modified="2018-01-31" version="1">MTVDYQYQIGGSLPQDSPTYVVRKADSELYESLKAGEFCYVLNSRQMGKSSLLVRTVQKLSADGIACATIDLSDIGNQQVSLDKWYGGVAYKLLCNFNLFNAVEFMTWWRERELMSPVQRLGELIEELLLVKISQNIVIFIDEIDSVLSFKESLDDFFALIRSCYNKRAHKSEYQRLTFALLGVATPSDLISDATRTPFNIGRAIELNGFSLQESLPLVKGLEGKFDNPQAVLKEILEWTGGQPFLTQKLCKLIVQGEEEGSAADFVADLTDVTEVGSAADFVADLTDVTDGIRTEVLTTNQLLIGEIVQSQIIDNWEASDEPAHLKTIRDRILRNQHRASRLLGLYQKILPVSEPPDCRGGAPVPALAGGIESDDTSEQTEMRLSGLVVKRGGKLTVSNRIYASIFNQNWVEKALCDLRPYAESLTAWIVSSCQDESRLLRGQALQDAREWAAGKSLSTQDYQFLAASQEAEFAELCDREKQTQAEIELLRRENQLLEQLSAEQKLRKSTQIKLWREQQLKVQIFTGSAAILISILIAAFWVQPSIEERNNKILTLSLFSETLFAADKKPEALIESIRAVQEMNRSLGVTSDIQVRVLTALEQVVYSFNQPMIFRAATAKLGFVTFSPNSQMLATVSDDNTIKIWQKNGNLKAVLIGQTNQIINVTFSSDSQRLVSVSDDNTVKVWQVDGKLIQNLKENKDQVKNTAFRETNQIIASVVGAENVKILSPNGTLISMFKHPNQITNVSLSPDRQILVSASADKMVRLWKIDGTLLKTLKGHRSAVSHASFSPDGKTIASASADGMVILWNLNVEDLLVQGCNLTRNSLQVKSQLQESDRHLCDGITNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F116</accession>
    <name>A0A2G4F116_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Photosystem II reaction center protein K</fullName>
            <shortName evidence="9">PSII-K</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">psbK</name>
        <name evidence="11" type="ORF">CP500_010760</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PsbK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55452">
        <property type="protein sequence ID" value="PHX55452"/>
        <property type="gene ID" value="CP500_010760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00441">
        <property type="entry name" value="PSII_PsbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003687">
        <property type="entry name" value="PSII_PsbK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037270">
        <property type="entry name" value="PSII_PsbK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35325">
        <property type="entry name" value="PTHR35325"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02533">
        <property type="entry name" value="PsbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161037">
        <property type="entry name" value="SSF161037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="2 9" id="KW-0674">Reaction center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="propeptide" id="PRO_5013977881" evidence="9">
        <location>
            <begin position="1"/>
            <end position="8"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023496719" description="Photosystem II reaction center protein K" evidence="9">
        <location>
            <begin position="9"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="45" mass="5036" checksum="4ABF74D543789A6B" modified="2018-01-31" version="1">MEAALLLAKMPEAYSIFEPLVNVLPVIPVFFLLLAFVWQAAVGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F122</accession>
    <name>A0A2G4F122_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55460">
        <property type="protein sequence ID" value="PHX55460"/>
        <property type="gene ID" value="CP500_010800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="85" mass="9900" checksum="783BF1E61BA11459" modified="2018-01-31" version="1">MARTPSEYSVHLLLSGGHREEVRFATLQDFQKWYSTVLVPKQESKEFLNVPIKNIQGEYMVIRPTSVEAIRVEPIFNSSVERFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F125</accession>
    <name>A0A2G4F125_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55438">
        <property type="protein sequence ID" value="PHX55438"/>
        <property type="gene ID" value="CP500_010880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8917" checksum="96DA87A9F379DD76" modified="2018-01-31" version="1">MRLLISKHFSKKKNRLHLSEYSQVSTKVRSQLQINQEVRSAASVLINLIYLLAAYDKLPQINYQKSLKNNKKRDCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F142</accession>
    <name>A0A2G4F142_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55480">
        <property type="protein sequence ID" value="PHX55480"/>
        <property type="gene ID" value="CP500_010685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="6"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="322" mass="36254" checksum="592A5AA18F101AE2" modified="2018-01-31" version="1">MQKDLSFVIPVHNEEATLKILFEKIQIVMSQTGIDNYEVIFIDDGSRDYSWREIVDLAKNNPKLIKAIKLRRNFGKSAALAAGFRNSAGRIIFTLDADLQDDPAEIPRFLDHLELGFDLVSGWRRKRNDPISKTLPSKLFNAVACLMTGVQMHDMNCGFKAYRKEVLASIKLYGELHRYIPALANNLGFKIGEVVVEHHSRKHGKSNYGWERYARGFIDLLTVLATTHYLQKPGHLFGGLGLSFGLVGFVSLAYLIVIWFLNLAGMNFGPIGNRPLLFFGILCTILSVQLISLGILAELMARNVDADYVDKQICEIIDDSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F175</accession>
    <name>A0A2G4F175_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55503">
        <property type="protein sequence ID" value="PHX55503"/>
        <property type="gene ID" value="CP500_010370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="14150" checksum="EFF0EEE0C0BD9C7A" modified="2018-01-31" version="1">MGFALNFKPGQIVSLELGNTCLHSEVIQVVEARQVCWVRPLMLVVFQSGDDLGDRLSEDYTISDLRNGADLLWPLSLFQAALDTEVISLLSQLYSLDSEKKDAVIASRQLRDFVDRVWTAFPTAFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1C6</accession>
    <name>A0A2G4F1C6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">mfd</name>
        <name evidence="11" type="ORF">CP500_011510</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55267">
        <property type="protein sequence ID" value="PHX55267"/>
        <property type="gene ID" value="CP500_011510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="635"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="821"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1169" mass="130707" checksum="8C2F121B07780369" modified="2018-01-31" version="1">MTFSSIIRILGRSPLATELLNKLKRHRYVQLNGVARLPKGLVASALAQQEGRSLLVVTATLEEAGRWVAGLEAMGWQTVHFYPTSEASPYELSYSDESEMTWGQMQVLADLVQKPEITTNSKPIAIVATERALQSHLPPPAAFEPYCLTLARGMTQDSKILDRQLASMGYDRVALVEMEGQWSRRGDIVDVFPVAAELPVRLEWFGDDLEQIREFDPSSQRSLDRIDRLVLTPTDFSGIVRGALGERLSLLTNREGAKGAKEEGEEGAEEGKVIKGLLGLAFEQPASILDYLPSNTLVAIDEPSQCEAHCDRWFESAQEQWESLVASLPKIHRSFAESMVDVEGFDRLYLSELAESAFSVPVSSSPPINLASRPVPVMPHQFAKLSQTLREDRDRGFTIFLISAQPSRSVSLLSEHDCPAQFVVNPRDYLAIDKLQLQHIPVALKYSGLAELEGFILPTFRIVLICDREFYGQHSLATFSYVRKRRRAASKQVDPNKLSPGDYVVHRQHGVGKFLKLERLTLDLETREYLLIQYGDGTLRVAADQLGALSRFRTVADKVPELNKLTGQTWEKTKTKVRKAVKKLAVDLLNLYAKRAKQTGYAFPPDMPWQQELEDSFPYQPTPDQLKATQDVKRDMEGDRPMDRLVCGDVGFGKTEVALRAIFKAVTAGKQVALLAPTTILTQQHYHTLSERFSPYPIEVGLLNRFRTETERREIHKRLATGELDVIVGTQAVLSKAIKFRDLGLLVVDEEQRFGVKQKEAIKALKTEVDVLTLTATPIPRTLYMSLSGIREMSLIATPPPSRRPIQTHLAPYDPEAVRSAIRQELDRGGQVFYVVPRIEGIDELAAQLQVMVPSARIAIAHGQMDASELESIMLTFSAADFDILVCTTIIESGLDIPRVNTILIEDAQKFGLGQLYQLRGRVGRAGIQAHAWLLYPKQSMLTDAAKQRLRAIQEFAQLGSGYQLAMRDLEIRGSGDILGTEQSGQMEAIGFDLYAEMLEEAIREIKGQEIPKVEDAQIDLSLTAFIPADYIGDLDQKMSAYRSVASASTPQDLQQIQADWCDRYGPIPLPAKQLIRIVELKQIAKQIGFSRIKPENKQHIVLETPMEEPAWNLLKANLPDHLQSRFVYSKGKVTIRGMAVLPAQKQLDNLIDWLGKMQGALPEANVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1F4</accession>
    <name>A0A2G4F1F4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system HigB family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55579">
        <property type="protein sequence ID" value="PHX55579"/>
        <property type="gene ID" value="CP500_010135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018669">
        <property type="entry name" value="Toxin_HigB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09907">
        <property type="entry name" value="HigB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="11761" checksum="FA716F5EEA34C9A8" modified="2018-01-31" version="1">MHIISYRRVREYSETHADCGEALDNWFKIASKAKWSNLIEVQSVFPKAEAVGGFTVFNIKGNNYRLIVSIDYESQLVYIKYILTHAEYDKEKWKNDRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1G4</accession>
    <name>A0A2G4F1G4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55578">
        <property type="protein sequence ID" value="PHX55578"/>
        <property type="gene ID" value="CP500_010130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039060">
        <property type="entry name" value="Antitox_HigA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40455">
        <property type="entry name" value="PTHR40455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="15508" checksum="3A5D6C4C3D6C09CE" modified="2018-01-31" version="1">MTVTFNPDKYKELLSQYQPKIIRNEADNEKALAMVEELMHQRDRTPEENELYELLIALIEKFEQEYYAPGTTATPRSILLFLMEQRELQPADLVPVMGSEKRVSEVVNGDRDISKELALILGSFFHVEPSLFCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1H9</accession>
    <name>A0A2G4F1H9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_010030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55606">
        <property type="protein sequence ID" value="PHX55606"/>
        <property type="gene ID" value="CP500_010030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="347"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="382"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="418"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="452"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="486"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="520"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="554"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="659"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="693"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="740" mass="84142" checksum="42ABBCA87D73801E" modified="2018-01-31" version="1">MLDKTLNGQYEIIRFLGKGGFGETYIALDKNKLKSQCVVKQLKPKNTDIDTLKAAKKLFDREAKILKQLGHHNQIPKLLAHFEEDKEFYLVEEFIDGNDLKKELEAVKQFSEQQVIALLRDVLEILKFVHQKGVIHRDIKPSNLIRRRHDGKTVLIDFGAVKEVTTQDTSSDGITSFTIAVGTRGYMPNEQQGGKPRFSSDIYALGMTAIHALTGMSPPTPSNKFSNQLQEHSRTGEIIWRQYAQVSNQLAAILDKMVKTHYRDRYDRAEDVLKDLQKLSYSSDTTSGTDFSTIATRKLALLKLPKLKYILVGLAAIGLAIGGSLTIPQFLVSNKSEQPPSPKPSTATDFVKQGNDLYNSKKYEEAIKAYDEALKGNPDKPEEIWNSRGLALSKLEKYQEAVDSYDKALAIRPNDADADALNLKAIALEKLNKLDDAIATYDRAIKIAPKNHTILNNRGLALYNKGKIEEGLKDIEKSLELDPQDYNTWYSKGIFFHKLKKYKEAVVAYDRAINIKPGLPETWVIRGHALVDLQRYKEAVYSYDEAIRNKPDYLEGWVGKGRVLRDLSRYEEALTAHDKALELQPNDIGIWEMQIDSLNNLKRYDQALEYFLKATKNITPSVNLLNLHVISLYRLGRYEEALNFCEQILKKDDSSLTASFVWRNKGASLNKLKRYSEALPAYEKSLSIEPSNAQFWFEKGKILFELQQYKEAVAAYDKAIELKPDYQEAKDARKLAVEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1J5</accession>
    <name>A0A2G4F1J5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Potassium-transporting ATPase KdpC subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP phosphohydrolase [potassium-transporting] C chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Potassium-binding and translocating subunit C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Potassium-translocating ATPase C chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">kdpC</name>
        <name evidence="13" type="ORF">CP500_011370</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the KdpC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55337">
        <property type="protein sequence ID" value="PHX55337"/>
        <property type="gene ID" value="CP500_011370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00276">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003820">
        <property type="entry name" value="KdpC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30042">
        <property type="entry name" value="PTHR30042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02669">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001296">
        <property type="entry name" value="K_ATPase_KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00681">
        <property type="entry name" value="kdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="206" mass="22310" checksum="261FD35540E5DD5E" modified="2018-01-31" version="1">MREIIKAIRVTLVLWGITAIIYPLIMLAIGQLAFNSQANGSLITKQGVVVGSSLIGQSFTSEKYFWSRPSTTNYSSFPDYAPTNGENSTQRTGVSGASNLAPSNSDLLKRGNEKDGFQGVQVEIDRLKKAGIKPTADLVYTSGSSLDPHISEEAARAQVQRIAKVRSLNLNQVEILVSKNTDGRFLGIFGEPGVNVLKLNLALDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1V1</accession>
    <name>A0A2G4F1V1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DRTGG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55726">
        <property type="protein sequence ID" value="PHX55726"/>
        <property type="gene ID" value="CP500_009200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010766">
        <property type="entry name" value="DRTGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07085">
        <property type="entry name" value="DRTGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DRTGG" evidence="1">
        <location>
            <begin position="220"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="369" mass="39998" checksum="3DE97538D5B85924" modified="2018-01-31" version="1">MRSKGVPKLTKYLLIGSTKAYSGKSAIALGMALGLRDKGFAVAYGKPLGTCFSSDVAGAEEEDVRFAIETLKLSESQMPSTLLSLDEETVHKRLRGEDQTDYRQSLAQYLQKQSTDVVLLEGPANLEEGSLFDLSLTQVAEAVDASVLLVTRPIDLYVDDLLSAKQRLGSRLLGVVLNDVPSDKLESITSTVRPFLEAKGIPVLGILPRSALLRSVSVKELVHQLKAEVLCRPDRLDLMVETLTIGAMNVSSAMKYFRKARNMAVVTGGDRTDIQLAALESSTQCLILTGHLPPSPLVIGRAEEMEIPVLSVDLDTLTTVEIIDSTFGNVRLHEKIKVECVTQLMAEHFDIDTVTASLGLAGQGGFILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Z2</accession>
    <name>A0A2G4F1Z2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenate reductase, glutathione/glutaredoxin type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">arsC</name>
        <name evidence="2" type="ORF">CP500_008880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55793">
        <property type="protein sequence ID" value="PHX55793"/>
        <property type="gene ID" value="CP500_008880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008794">
        <property type="term" value="F:arsenate reductase (glutaredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014062">
        <property type="entry name" value="Arsenate_reductase_gluta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02689">
        <property type="entry name" value="ars_reduc_gluta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="1">
        <location>
            <begin position="2"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14577" checksum="8B548DA209E91059" modified="2018-01-31" version="1">MKKVMFVCKRNSCRSQMAEGFAKTIGDGKIGVTSSGLESSRVHPTAIQVMSEIGIDITDQTSNPLSEFNAEDYDAVISLCGCGVNLPEAWVLREVFQDWQLDDPDGQPIETFHRVRDEIKARVEKLVDSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F231</accession>
    <name>A0A2G4F231_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55820">
        <property type="protein sequence ID" value="PHX55820"/>
        <property type="gene ID" value="CP500_008665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="12636" checksum="EF61D1E72A832624" modified="2018-01-31" version="1">MTYLNPTRTVRRGRLFPEIQWSEEKKAQWQAEREAFYQRCKPIFDRLKPELMKTHYNWYMAVEPDNGEHFIDKDDMLVANIAHEKYPKVKLQVFRINETGVCGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F271</accession>
    <name>A0A2G4F271_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_008615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NodU/CmcH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55873">
        <property type="protein sequence ID" value="PHX55873"/>
        <property type="gene ID" value="CP500_008615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031730">
        <property type="entry name" value="Carbam_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038152">
        <property type="entry name" value="Carbam_trans_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003696">
        <property type="entry name" value="Carbtransf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16861">
        <property type="entry name" value="Carbam_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02543">
        <property type="entry name" value="Carbam_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbam_trans_N" evidence="2">
        <location>
            <begin position="3"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Carbam_trans_C" evidence="3">
        <location>
            <begin position="451"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="659" mass="74699" checksum="C169B82411CC9998" modified="2018-01-31" version="1">MNILGISAYYHDSAAALISDGEIIAAAQEERFSRKKHDARFPKNAIAYCLKEAKIDLQQLDRIVFYDKPLVKFERLLETYLAYAPNGFRSFLTAMPIWLKEKLYLKTILKRELAELANCKTSKLRPSLLFTEHHQSHAASAFFPSPFQKAAVLCLDGVGEWATTSVWLGEGNQLTPQWEIDFPHSLGLLYSAFTYYTGFKVNSGEYKLMGLAPYGEPKYVDKILNYLIDLKDDGTFRLNMDYFNYTVGLTMTNQKFDELFEGPPRKAEGKLTQREMDIAASIQVVTEEVVLRLCRTVKKELNVDYLCLAGGVALNCVANGRILREGIFKDIWIQPAAGDAGGALGAALAIWYQYCESERNVNLNLPANIIEPQKSQVIPTSEVAEDGTEILTTNQPVATVTKSVAHLTCRDQMRGSYLGPKFADTEIIEYLDAVKASYHRLDDAELMPQLAEILEQGNVVGWFQGRMEFGPRALGGRSIIGDPRNAKMQSVMNLKIKYRESFRPFAPSILAERVADYFEMDHSSPYMLLVAPVKASLRIPMTAEQEQLFGIDKLNVPRSEIPSVTHVDYSARVQTVHKETNPRYYDLISHFERRSGCSILVNTSFNVRGEPIVCTPEDAYRCFMRTEMDYLVLENFLLPKSEQIPWKQDDAWKNEFELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2B4</accession>
    <name>A0A2G4F2B4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55882">
        <property type="protein sequence ID" value="PHX55882"/>
        <property type="gene ID" value="CP500_008275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013713718" evidence="1">
        <location>
            <begin position="21"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="154" mass="17066" checksum="557FD5437B37F489" modified="2018-01-31" version="1">MWKKVLAAGIILSSSLLPFARVEARAAQLQCVKVSGYDWERFNGSIVVGRKIYNPDSRLSLSNPYEVTCKLLEKVSVVNVSLAIPDTSEIQTVKIQIYIEGKLAKTVNVVRGVVTPFSVDLRGVTNFSVSYEQVGYRGSGRDAGIYAIQDWDYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2C1</accession>
    <name>A0A2G4F2C1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55911">
        <property type="protein sequence ID" value="PHX55911"/>
        <property type="gene ID" value="CP500_008015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7614" checksum="7437C40B43749BC3" modified="2018-01-31" version="1">MEVSIQTLVLTDKETMAKLKIAMLESETAAQLAAIIIDYTHEEMMLVFNELEWEQQNRIKTIWND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2M4</accession>
    <name>A0A2G4F2M4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2808 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX55999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55999">
        <property type="protein sequence ID" value="PHX55999"/>
        <property type="gene ID" value="CP500_007525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021256">
        <property type="entry name" value="DUF2808"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10989">
        <property type="entry name" value="DUF2808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013558969" evidence="1">
        <location>
            <begin position="25"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="19088" checksum="222355628E08BF98" modified="2018-01-31" version="1">MRRLFSALAVTGCLLTGLPAISLAQGMPGFTIFGGPDRGNQLNYRLDYGKSGMSGDRYRLRIPSKKVSLAIAQLNISYPDYYKGEFDQKDIKVRVKNKTIELQEVIWDKENRFIEIYPKEPIAAGNNVEVVLSNVTNPSPGGMYNFNVRIRTPGDVPLLRYLGTWLLSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2P8</accession>
    <name>A0A2G4F2P8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_007690</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56026">
        <property type="protein sequence ID" value="PHX56026"/>
        <property type="gene ID" value="CP500_007690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="145"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="196" mass="22584" checksum="8BCFE591ED1E6911" modified="2018-01-31" version="1">MDIADYYRQLGLRSGASLSQVKAAYRQLARQYHPDVNPGNEAAKNKFITITEAYKFLVNIAPSPSDAAESKVPNSTQQQTVKVTRKPSPTENNQEFSAAEEKLKQDAYLQLQQLLKYQRFPRAIALVEGLAQRIPDDAEVRQWQAIVYQRWGRYLIGEKQVDKARIYLKKAVKTDPHNGALWAEVERDFRRLEQIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2R0</accession>
    <name>A0A2G4F2R0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Magnesium-transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_007470</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56063">
        <property type="protein sequence ID" value="PHX56063"/>
        <property type="gene ID" value="CP500_007470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="729"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="762"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="806"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="840"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="872"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="906"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="940" mass="102620" checksum="1D649F52855F5894" modified="2018-01-31" version="1">MSSNPLSSWHTVAIDKTLKELSSNKDAGLSSQQVSERLQQYGPNELEETGGRSPWSIFIDQFTNIMLLMLMGVAIISGFLDLKSNTFPKDAIAIFAIVILNGILGYLQESKAEKALAALKNLSSPLVRVVRDGKTSEIAAKDVVPGDIMLLEAGVKIAADARLIEASNLQVRESALTGEALPVTKQAEIELAADASLGDRLNLIFQGTEVVQGRAKSIVTNTGMQTELGKIAAMIQSVETEPTPLQKRMGQLANVLVSGAMILVLIVVIGGMISFQNGNIGFDTSRFEELLKVSLSMAVAVVPEGLSAVVTVTLALGTKRMVKRNALIRKLPAVETLGSVTTICSDKTGTLTQNKMVVQRVHAGNSDVRIGGEGYAPIGIFTDRQKSTQINNLEEYPELESLLIACAVCNDAFLQHEQQEWTILGDPTEGALLSLAAKAGIYKDIQSQLLPRTAEFPFSSERKRMSVICELPGRSHNSGFPAHEGQQPNHLMLTKGSPELTLERCNWIIIGDRVQPLTQEMRDRILAENNDMASSGLRVLGFAYKLWETVPPSDSEETSEQDMIWLGLVSMLDAPRPEVREAVVKCRDAGIRVVMITGDHQLTAKAIAQDLGIASLGDRVLIGQELENLSQEELKQQVDQVSVYARVSPEHKLRIVQALQSLGKFVAMTGDGVNDAPALKQADIGIAMGITGTDVSKEASDMVLLDDNFATIVAAAEEGRVVYTNIRRFIKYILGSNIGEVLTIAAAPLMGLGGVPLTPLQILWMNLVTDGVPALALAVEPAEPNVMKRPPFSPRESIFARGMGSYMIRIGIIFAILTIAMMSWAYGYTHGATYQGDPNTWKTMVFTTLCLAQMGHAIAIRSNTQLTIELNPFTNIFVWGAVIVTTFLQLMLIYVPPLRAFFGTHYLSLFELMVCFGFSALMFIWIEMEKLFIRFYKRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F311</accession>
    <name>A0A2G4F311_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_006975</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56125">
        <property type="protein sequence ID" value="PHX56125"/>
        <property type="gene ID" value="CP500_006975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="214"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="453" mass="50637" checksum="9FCD19742FA8CB3F" modified="2018-01-31" version="1">MFQTTRRRLAIWYTAVTAVLLLVFATGFYFYVRNTLIDRIDDTLNHVVEVVERTLVIEPLTSRTIGYTTKSQVNIQASFRDSTDAVEDDHIDLEWFSPTGKLLWSTLSEPLNIPIHANRTGETVWVINHKLQSENYSLRQVTQRVEIGRQVLGYLRVSHPWFEVTKPIRQLILDLILGAGLTLICVAAIGWLLSGLAIAPVRESYGRLKQFTADASHELRNPIATIQTNVQVALAEPDIDPQQHQQLQVIERLTRRLGRLVDDLLFLARQDSGIVQQEWVDVPLDALLIEVIEEQLAIATTQNLSLSLEIADSPNAKDNFTVLGDWDQLARLFTNLVSNCVQYTRSGGKIQVELQLASKSKITASMLNPALQVKITDTGIGISPESLPHIFDRFYRADPARTHRSAAGSGLGLAIAKVIVENHRGQIHIDSQLSEGTVITVSLPAHKSEISRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F314</accession>
    <name>A0A2G4F314_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56164">
        <property type="protein sequence ID" value="PHX56164"/>
        <property type="gene ID" value="CP500_006885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="501" mass="56714" checksum="3516BA2DDD106D1E" modified="2018-01-31" version="1">MVNLISENPSLILAAEDCPAEDFEQLHYFSKQEQRFISNLIAHGPVLLKGARGSGKSALMIEASRRMYPANPLSSAFGIYISLRHLELLRSEGEKYERMLCQLIIDAVNQTIIKTADIFEFYPLPNITSLQRELSSLSIASRKRIVILFDDAAHIGREAPLHEFFDIFRTLSSSIISCKAAIYPGVTKFGTRFDVYNDATVIDVSRNDELEGYNANFTEIIKKRSFMGIPQESFSGELNVENVAGFMGRAVLGNMRGFIFAWNHLSKNCKDGKKISYANLTKTLIDIASNYYWPLIEELKPKLGIYAPMIEPATDIAELIFREAGEDNKQDVLILREIAQRLSKPLEILEYTGFISIRDVSRAMKSRGRGTRYSLNLCTLLEKIRGARVTREIYSRWLNESNERNESLELHKTSELFKMQLPELLKDGEMLIFKEDIGKLKKSNAYPYGLTQDKIDILKAADYDTVSALAEASDKSLLALNDIGEATLKRIRSTIAQAIWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F329</accession>
    <name>A0A2G4F329_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56162">
        <property type="protein sequence ID" value="PHX56162"/>
        <property type="gene ID" value="CP500_006875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="10"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="92"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="222" mass="26094" checksum="6D60E471B23D18D8" modified="2018-01-31" version="1">MIVPTEGISNYPILYSFRRCPYAMRARLAVVASGIVCELREVVLRDKPPEMLDVSPKGTVPVLVDRDGRVFDESIDIMFWALEQHDPEKWLIPEQGCVAEMLELVDKCDRGFKYHLDRYKYPNRYEDTEAIVHRTEGYLYLEILNSRLRETRYLFGNRVALADMAIAPFVRQFAHTDIEWFNQQQLPHLQAWLSGFLHSEIYNQIMQKYPKWESGNECVVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F336</accession>
    <name>A0A2G4F336_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Photosystem I reaction center subunit XII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_008535</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cellular thylakoid membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the phycobilisome linker protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55877">
        <property type="protein sequence ID" value="PHX55877"/>
        <property type="gene ID" value="CP500_008535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008213">
        <property type="entry name" value="CpcD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001297">
        <property type="entry name" value="PBS_linker_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038255">
        <property type="entry name" value="PBS_linker_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016470">
        <property type="entry name" value="Phycobilisome"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01383">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00427">
        <property type="entry name" value="PBS_linker_poly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005898">
        <property type="entry name" value="Phycobilisome_CpeC/CpcI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01094">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51441">
        <property type="entry name" value="CPCD_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51445">
        <property type="entry name" value="PBS_LINKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <feature type="domain" description="PBS-linker" evidence="8">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="CpcD-like" evidence="7">
        <location>
            <begin position="235"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="294" mass="32898" checksum="FFB596EF29AA07DE" modified="2018-01-31" version="1">MVFGPASRLGVSLFEETPSLELMPGHSQEEVETVILAVYRHVFGNAYVMESERATIPESQFKRGELSVREFVRALAKSDAYRSRFFDTCPRYRFIELNFKHLLGRAPDGLEEMRTHSTILDTQGFEAEIDSYLDTDEYQNAYGENIVPFYRGYKTQPGKNMVGFTHMFALLRGASSSDFKGSISGKAPVLNKFVIQETPLPIVPPSGGTVGDGWAFQEYAMNARSRAGLGAQAEGKVYRITVTGYRSSGTTVINKVSKFRRSNQVYLVPFDRLSQEYQRIHKQGGVIASITAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F345</accession>
    <name>A0A2G4F345_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56193">
        <property type="protein sequence ID" value="PHX56193"/>
        <property type="gene ID" value="CP500_006705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8440" checksum="3EF526D18C171365" modified="2018-01-31" version="1">MKIDRITSNPKRMNGQPCIRYLRLTVRRVIELLATYPDRAELHQEFPELEDEDIRQALIFVSSVIIVLVTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F377</accession>
    <name>A0A2G4F377_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TIGR04376 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56185">
        <property type="protein sequence ID" value="PHX56185"/>
        <property type="gene ID" value="CP500_006665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030816">
        <property type="entry name" value="CHP04376"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04376">
        <property type="entry name" value="TIGR04376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="22988" checksum="A1BA26A1EBA98C46" modified="2018-01-31" version="1">MGLFEDFSRLLETKLEEFLRSNPHLELQAIEEQLKEQEEDTLRLILEIQKQEKTLQAEILSTAQEIQRWNDRINKAKASQRLDLAQAAQERQATLLRQGNQRWGQMQGCKERIEKAKELYRQIQVRRKEVRAKAAEAATHNATKTATKTEQSWDTKGWNQSSNYSSFNAADPLEEKFQIWEADEELDRMKRNLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3A6</accession>
    <name>A0A2G4F3A6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrate ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56239">
        <property type="protein sequence ID" value="PHX56239"/>
        <property type="gene ID" value="CP500_006415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="34"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="332" mass="36661" checksum="5A7A53A0036D8F03" modified="2018-01-31" version="1">MKSKQLTFLTLLFLPFLMAIFIKGCSFGTGALKPFKVGLNTWPGYQVALYAQATGLFRKHGLDVEFVRFTNQQDNIRATMRGAQDASFVPLAEVIQVDPSQEAPVYIMVADISTGSDGIVAESQITSVKDLKGKKVSVKLGTVPHLVLLEALKANQLQPNEIEIVDAINERGAAMLKQGKVSASVLWEPLLSNTAQAEGRKVIYTTADVDSVVIDGLATRSSITTTKQDELTRFIETWFDVMKDLETKPQEVFASVAKQLGTTVEIFAKDYAGLKKGNLAMNRRMFEGGRLQAASQQTRQLLLADPRHGRLIRDYVEINAQPIVKATKNWQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3C2</accession>
    <name>A0A2G4F3C2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_006395</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56235">
        <property type="protein sequence ID" value="PHX56235"/>
        <property type="gene ID" value="CP500_006395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021147">
        <property type="entry name" value="DUF697"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05128">
        <property type="entry name" value="DUF697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="3">
        <location>
            <begin position="132"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="547" mass="59995" checksum="112AEF0BA66E7EF1" modified="2018-01-31" version="1">MPLPRLLTLIAAFCLALGLIIGLVSSLTGLYTQVAWSASPLLANLLILAILVLLGTLIFAIFYYFKLLQSPPKSKGKRIIKPKIPVIKSEAAAENLKAIRQQVDRIQDEVARQALLLRAREIEASMARGSIRIVVFGTGSAGKTSAVNALVGRMAGQVGAPMGTTEVGATYTLKLKGIDRELAITDTPGILEAGVAGTYREELARQLAASADLILFVLDGDLRKSEYEPLRNLAEIGKRSIVVFNKVDLYPDSDKDAILDRLQERVKGLVAAMDVVAISANPQKVVLEDSTIFQPDADIMPLIRRVAAILRAEGEDLIADNILLQSQHLGDQARKLIDAQRRRQADKVVERFQWIGAGVIAVTPLPVVDLLATAAVNAQMVVEISKIYGCELNIDRAKELAFSLAKTLASLGIVEGVIQVVSRALQLSIAGFVLGKAIQAVSAAYLTRIAGKSFIEYFRHDQDWGDGGIAEVVQRQFQLNRKDEFVKAFVKDAIARVVEPLNLYQQSGESELEMAAELESEMKPELLYQSQEYEDWETYSNKRNDEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3C8</accession>
    <name>A0A2G4F3C8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_006295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56270">
        <property type="protein sequence ID" value="PHX56270"/>
        <property type="gene ID" value="CP500_006295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014324">
        <property type="entry name" value="ABC_heterocyst_DevA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02982">
        <property type="entry name" value="heterocyst_DevA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="22"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="56"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="26115" checksum="F848623933DF81B3" modified="2018-01-31" version="1">MKSTTLNPTANNLQISEPVISMHKLDHYFGQGQLKKQVLFDITLQINAGEIVLMTGPSGSGKTTLLTLIGALRSGQSGSLKILGQEMCNASSDKLVNTRRNIGYIFQAHNLHRSLTALQNVQMGLEVHGNLSRSEMRDRSAKMLELVGLEQRINYYPDDLSGGQKQRIAIARALVSQPQIVLADEPTAALDSKSGREVVNLMQKLAKEQGCTILLVTHDNRILDIADRIVNMEDGKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3D7</accession>
    <name>A0A2G4F3D7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Adenylyl-sulfate kinase</fullName>
            <ecNumber evidence="1 2">2.7.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">APS kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">ATP adenosine-5'-phosphosulfate 3'-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Adenosine-5'-phosphosulfate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">cysC</name>
        <name evidence="3" type="ORF">CP500_006365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Catalyzes the synthesis of activated sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 2">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the APS kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.25" evidence="1 2"/>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56280">
        <property type="protein sequence ID" value="PHX56280"/>
        <property type="gene ID" value="CP500_006365"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00065">
        <property type="entry name" value="Adenylyl_sulf_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Phosphoserine intermediate" evidence="1">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="11"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="174" mass="19135" checksum="A91DBB44CB5B0DDB" modified="2018-01-31" version="1">MDKGFILWFTGLSGSGKTTISKALEPELKARGCKVEILDGDVVRTNLSKGLGFSKADRDTNILRIGFVANLLSRNGVVAITAAISPYQAIRDEVRAMESNFVEVYVKAPLEVCEARDIKGLYAKARKGEIKGFTGIDDPYEEPINPEIICYTDQESLQESVTKILGKLEELGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3E2</accession>
    <name>A0A2G4F3E2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cyanobacterial phytochrome A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_007875</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the phytochrome family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55997">
        <property type="protein sequence ID" value="PHX55997"/>
        <property type="gene ID" value="CP500_007875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009584">
        <property type="term" value="P:detection of visible light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013654">
        <property type="entry name" value="PAS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001294">
        <property type="entry name" value="Phytochrome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013515">
        <property type="entry name" value="Phytochrome_cen-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043150">
        <property type="entry name" value="Phytochrome_PHY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08446">
        <property type="entry name" value="PAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00360">
        <property type="entry name" value="PHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01033">
        <property type="entry name" value="PHYTOCHROME"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <feature type="domain" description="PHYTOCHROME_2" evidence="7">
        <location>
            <begin position="142"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="525"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="748" mass="84598" checksum="C9B162DEEE647327" modified="2018-01-31" version="1">MTIDLTNCDREPIHIPGLIQPHGVLLVLHNPTLEIVQVSRNTEAVLGRQPEELLGQPLSDLLDAKQIKLIQQCLAEDFERINPLNLSIKRRNKSIYFDGIVHRLEDAIVLELEPKKAKGKTDFFDFYQQVKGTITRIQKAPTLLNMSQIVVKEVRRITGFDRVMVYRFAPDGAGSVIAEDTNQEASYLNLHYPASDIPKQARQLYTLNWLRLIPTTSYQPVTLIPATNPFTNQPLDLSLSVLRSVSPIHLEYLQNMGVDASMSISLMHDQKLWGLIACHHLSPKYVPYNIRTVCEFIGQVMSVELTNKTASEDIDYKMQLKSLQTQFVEALSQAENLLDGMVQLKSQLLNLVNATGVVICSGNQYFQVGVSPSEEAVHALLDWIKPQLHNSLFETRSLSKHYPAAESFKAIASGVLALEISKVHRNYILWFRPEVMQTVNWGGNPNKPVEVSVDGSLRMSPRLSFDLWQETVQGCALPWKPCEIEAVAELRSLIVGVVLRQADELSLMNFELQRSNEDLDSFAYIASHDLKEPLRGIHNYANFLMEDYEEVLDEDGIAKLQTLVRLTQRMEDLINSLLYFSRLGRTELMRQTVNLDELVHQTIATLTIARPQNEVEFRIPQPLPSIEGDLAQVNELLTNLISNAIKYNDKASKWIEIGFISGNEENSDLYPLTFYVRDNGIGILQQHLDKIFQIFRRLHGRDDFGGGTGVGLTIARKIVERHGGRIWLESTLAQGSTFYFTLAAETIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3E8</accession>
    <name>A0A2G4F3E8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56303">
        <property type="protein sequence ID" value="PHX56303"/>
        <property type="gene ID" value="CP500_006110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="7867" checksum="38A0CF835923CEDA" modified="2018-01-31" version="1">MSRSHFGTIRAIALSDKKGDRPLGFGMGKAIALSDNKGDRTLGFDTGKAIALLVIWGKRAIAINFYSRMRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3I8</accession>
    <name>A0A2G4F3I8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56308">
        <property type="protein sequence ID" value="PHX56308"/>
        <property type="gene ID" value="CP500_006140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="11115" checksum="E850C3B663D8F48E" modified="2018-01-31" version="1">MTTQSASRYVARHPEILQGEPIIAGTRTSVRAIVELWRLGITPEEIPMHLPHLKLAQIFDALSFYLDNQEEINTYIERNRIPEELIHPAVKAAMKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3X6</accession>
    <name>A0A2G4F3X6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56462">
        <property type="protein sequence ID" value="PHX56462"/>
        <property type="gene ID" value="CP500_005260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="431" mass="49823" checksum="B3C5A6C1EC2B72E9" modified="2018-01-31" version="1">MSNSWTDSYNRPSYEAEQLLYNHWLELVQVEQPAEIINRFRTLFIHCDNYPDRTIVAALEKIATSKEAEPELKYILNRCCHIAINRWQTHPHKQAAIPELIALFEEVPKVIFGYNQSRAIGHITRIVNQFTESEQYLALKRLSKVITHNSEDTSSKTPTKLALGTLIPRYPYLYSHCLLSDDSNYEQQKVIKTIQARKQHQFEINLSQYVAHQVRKVQTARRQTSLSFGRTIQNIKNPTLLSDPELFFALKQFVGKVEAGNTYRQIAGSFLANTSQTTQCYGSFKDDLYEYLISSLTDHRYSKGQFKDKLYKQLQSTFPHSDSQQFNEFLMMRTCSQLLNFLVVESQKRPNHFVFIDLISNLGPTETTGLLLKIVLICDKVKPYLEKRLAILFGHYEFSAPAAVMWLVKALENLNLALSTNFGKVDVSFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F407</accession>
    <name>A0A2G4F407_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MORN motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56451">
        <property type="protein sequence ID" value="PHX56451"/>
        <property type="gene ID" value="CP500_005465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="295" mass="32755" checksum="FBA86DDB695842D1" modified="2018-01-31" version="1">MSEQGIVKAIVVGVIVAVVGSSIHVFQKEIKQCIGLEVGFCPLTSEVTYDGGGRYKGDTLNGKPQGKGVFTTVKGDRYEGEFKNGTYEGKGTFTYAANDAGYERYLGEWQNGKRNGKGTLNYVGGHRLEGEWKDDNYIKGVYIWKNGDRYEGDWSKDGTKRNGKGTLTYADGRRYVGEFRDDEINGTGSMTYPKDSKTQSYDGEWKNGKYNGKGKVIWSNGRSYDGYWRDDKRNGQGVFTWADGDRYDGGWLDDKRDGFGVMIKSDGTRKTELWDNGQLLTSPSPSPSPSPSPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F488</accession>
    <name>A0A2G4F488_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56604">
        <property type="protein sequence ID" value="PHX56604"/>
        <property type="gene ID" value="CP500_004520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="271" mass="26602" checksum="44E08D367DE1F7FE" modified="2018-01-31" version="1">MTQVTNPTTPASSAPNTQGGLDIRGVAGDNRLNAGTGNDNVQTGRGNDIISADAGNDTARGGKGNDFVDGGAGNDVLSGDAGNDTVAGGAGDDAIYGDTPSRSGGGNDVIGGGDGNDLIFGQAGNDVLNGDAGNDVLWGGKGADTINGGAGNDTISGDGGTDLLTGGAGSDTFYFASIGGSDIDTITDFTPGEDKIRMKQGGTLAILGTAVDATEFVVITDNAQLTAAANANKVIYNSASGLLYFNNAGNAVPVAQLTPGLTIGTSNFELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4E5</accession>
    <name>A0A2G4F4E5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56581">
        <property type="protein sequence ID" value="PHX56581"/>
        <property type="gene ID" value="CP500_004875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="13539" checksum="844BDBA79CA21E49" modified="2018-01-31" version="1">MESQGENKDVVWLRGEVKTPPFSASARIEAGMLLRMLQNGEILAMPVSRPMPSISPHCHELRIDDSEADKQWRIIYRIDSDAIVIADVFQKNTQKTPKRVIENCQRRLRLYDQSSGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4I6</accession>
    <name>A0A2G4F4I6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56694">
        <property type="protein sequence ID" value="PHX56694"/>
        <property type="gene ID" value="CP500_004170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="289" mass="32859" checksum="FDAE26B204DF1589" modified="2018-01-31" version="1">MRILFTIAHFYNPSGDGKHASQRNDPQPRLNALTACITSLQALYGKSQCMIHIGECATIPANQHQNHEIDIVVCTTQGYHLLAQLPIQPKSFIHHATQCEPLLLGFECQAVLRACLDKYDYFCYLEDDLILHDSWFFNKLNWFRHHGGNGNLLQPNRYEVSPQAPVFKAYIDGDLTPSATAKFQNVEEQRQLLGKIMEQKIAFERALNPHAGCYFLNAEQMKHWVSQPDFLDRDTSFIGPLESAATLGIMRNFKVYKPVAAYANFLEIQHFGSSFLKLIGNKVRLSEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4M7</accession>
    <name>A0A2G4F4M7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56722">
        <property type="protein sequence ID" value="PHX56722"/>
        <property type="gene ID" value="CP500_003675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="11785" checksum="44914217D5939F9B" modified="2018-01-31" version="1">MQYLSSNTLLAQSPPEPSQERRHPPRIDFAAAAKQLGVTEAQLIEALGLPTKPPAPPSDNNCPPPPPPPRLDIPGAAKKLGVTEAQLIQILGIPPRPPGDRNLPQNSEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4P6</accession>
    <name>A0A2G4F4P6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56754">
        <property type="protein sequence ID" value="PHX56754"/>
        <property type="gene ID" value="CP500_003850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8036" checksum="7283E33E413D4A62" modified="2018-01-31" version="1">MLVASGDSIFFEKTALNVLIYINRKIVDQINAALSYIEENCAQIETEYCRVRQPTAFTLAFGAIKLTHPTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4S9</accession>
    <name>A0A2G4F4S9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Molybdenum cofactor biosynthesis protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the biosynthesis of molybdopterin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MoaB/Mog family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56756">
        <property type="protein sequence ID" value="PHX56756"/>
        <property type="gene ID" value="CP500_003865"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012245">
        <property type="entry name" value="MoaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43232">
        <property type="entry name" value="PTHR43232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006443">
        <property type="entry name" value="MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="3">
        <location>
            <begin position="17"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="168" mass="18203" checksum="D86B0B219A19735E" modified="2018-01-31" version="1">MTQIPHPDLSEMTVNCAVITISDTRSAETDNSGVLIKKLLKDAGHVVVAYTVVKDDATKIILQMQAVCEREDVDAIIFSGGTGIAPRDTTYDVMESLLDRILPGFGEIFRFLSYQEIGSRAIASRAVAGVYQGKLVFSLPGSKNAVKLAVEKLILPELVHLVMQLRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4U9</accession>
    <name>A0A2G4F4U9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56823">
        <property type="protein sequence ID" value="PHX56823"/>
        <property type="gene ID" value="CP500_003230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8322" checksum="A0F73EFEEEA9667B" modified="2018-01-31" version="1">MLTTVREVYDRVLSTLSPKDRLRLATLILNDLVQQNLSVVDESETWTEEDKLDITTFSLQYAATIFSENEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F541</accession>
    <name>A0A2G4F541_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Shikimate dehydrogenase (NADP(+))</fullName>
            <shortName evidence="3">SDH</shortName>
            <ecNumber evidence="3">1.1.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aroE</name>
        <name evidence="6" type="ORF">CP500_002690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.25" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56904">
        <property type="protein sequence ID" value="PHX56904"/>
        <property type="gene ID" value="CP500_002690"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="4">
        <location>
            <begin position="11"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_C" evidence="5">
        <location>
            <begin position="300"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate binding" evidence="3">
        <location>
            <begin position="19"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="178"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="337" mass="35521" checksum="FD66F3D453A81725" modified="2018-01-31" version="1">MIKGTTKLLGVIGDPIAHSLSPAMHNAAISHLGVDFVYLAFPVKPEDLKVALLGFGAIGIQGFSITIPHKQAILPLLSEVSPIARAIGAVNTVYLTDKGWCGTNTDVEGFLAPLQTPPTPPYQGGAKDVKFALESGNMTAQSCPPLYQGAAPQSCPPPYQGGARGGSDWSQKVAVILGNGGAARAVVAGCAQLGCAEIHVVGRNEQNLAEFQQSWVNSPMPVKSLRVHTWDNLSSLISHADLLVNTTPVGMYPQGEISPISASAIDRISVGAIAYDLIYNPNPTQFLKDAQLRGAQTIDGLEMLVQQGAAALKIWLNTDSVPVDVMRHALRKHLGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F595</accession>
    <name>A0A2G4F595_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S-layer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002715</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56909">
        <property type="protein sequence ID" value="PHX56909"/>
        <property type="gene ID" value="CP500_002715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="3">
        <location>
            <begin position="139"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="3">
        <location>
            <begin position="203"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="3">
        <location>
            <begin position="264"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="335" mass="36565" checksum="6182A367A763E326" modified="2018-01-31" version="1">MSSSQPPSREKRPLGFDELIAIVVAFGTMGSIFFWVTGKNPSQFSATNWQFPAVFSQPAAVPDSSKTLTPPPSSSDVFKPSATVIPAPSPLAPGSPLPEVVVPIPVIVPPVSAVPEQPIGRSTPAPPTTKSQPAKGKIAPVKFSDVPDKYWARPFIVALVDRKIFADFTDNKFRPDEPITRAELARLIKRMSDQEPRRKSLDFKDIKSSNSAASSIDYSVKTGYLKGYPNNEFRPDKPVPRVEVIAALASGLNLKPSKETTKTLQVYTDRKKLPKWAVNKVASATEAGIVVNYPKRQLLQPNRTATRAEVAAMLYQAMAKQGKVPAKSSQYIVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5D0</accession>
    <name>A0A2G4F5D0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57013">
        <property type="protein sequence ID" value="PHX57013"/>
        <property type="gene ID" value="CP500_002160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7067" checksum="0EF26B13448EBD80" modified="2018-01-31" version="1">MILNSLELTTTDKSNAAVDEVVSALTKEIAARAEIKKPEKNLQQNRLSLGETYLRILEAGGHLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5I1</accession>
    <name>A0A2G4F5I1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56998">
        <property type="protein sequence ID" value="PHX56998"/>
        <property type="gene ID" value="CP500_002620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="9011" checksum="D3A46631D0E87A21" modified="2018-01-31" version="1">MRKQTIQYTSPLDALVAVAKRLSLYEKQQKIDSEEFFNQYNQGLLSDDALFVEWANDYRHYLVLHQELAQRLNYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5K7</accession>
    <name>A0A2G4F5K7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosylglycohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57036">
        <property type="protein sequence ID" value="PHX57036"/>
        <property type="gene ID" value="CP500_002285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="334" mass="36515" checksum="BCBC6F420F309FFB" modified="2018-01-31" version="1">MTVPRLEQFRGCLIGQCLGDAVGCRVEGYPPEVCQNFVTYEVRLKKIKDRDRFGFPFGQYTDDSQLARELLQSYLACGQFDPSDYATRIADIFAQERIVGRGRSTEEAANRLIRGVAWQEAGTPAPSAGNGSAMRAGPIGLIFYDRPSQLIQAACDQGRITHQDSRCSAGAVAIAGAVAIALQSDTIETEPFLGQLSEWVAFVDSSFAALLKDLIEWVKLPPESAVELISKAGLPLNYQHSWQGISPFVVGSVLWSLYAFLRTPQDYWETLCTSIAVGGDVDTTAAMACAISGAFLGLEAIPKQLTELLNDRETWGLDELIQLADSCYQLKLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5R2</accession>
    <name>A0A2G4F5R2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase subunit sigma-24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57078">
        <property type="protein sequence ID" value="PHX57078"/>
        <property type="gene ID" value="CP500_002020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="27"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="128"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="188" mass="20899" checksum="A12F9834CD056938" modified="2018-01-31" version="1">MTAQKSGDESLLLVQIAQKDQTALAKLYDRYGRASYALAYKILGSVEEAEEVVLDVFSQIWQKAASYDVSRSRVDTWLFMLTRSRSLDRLRVLQRSFRAAVASLEDAKIAKSGIAEPMENAILEELSEQVKAALEKLPAEQRQAIELAYYQGLTCAAIATKTGIPMGTIKTRIRLGISKLRQALSEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5S6</accession>
    <name>A0A2G4F5S6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57075">
        <property type="protein sequence ID" value="PHX57075"/>
        <property type="gene ID" value="CP500_002005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="12504" checksum="C761E848F1DC749D" modified="2018-01-31" version="1">MSRKRPARSSNPDLRRGIAEIEAKLLSWLTPIRFKPLRLSHLTQKLRDRLLTLPVMMAVVLSLVYRRISGLSEVIRVLESEGLLWVEPFKVSKQALSKRLACLPPDAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5T3</accession>
    <name>A0A2G4F5T3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4079 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57122">
        <property type="protein sequence ID" value="PHX57122"/>
        <property type="gene ID" value="CP500_001600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025067">
        <property type="entry name" value="DUF4079"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13301">
        <property type="entry name" value="DUF4079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="159" mass="17147" checksum="62BB6923A3700B0B" modified="2018-01-31" version="1">MANLSEILEPIANQFRNLGIPEPITHWGHPAMMGIVVVAMGSFVGYTGWQGRLAADKDVAIKNRLDHRKIAPLMFLFIALGYTGGLLSLVMQHQPVMESPHFWTGSTIIVLLTTNSLISLTGFGGDKLALRAVHAYLGTTALALMVLHAAFGLKLGLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5V6</accession>
    <name>A0A2G4F5V6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57105">
        <property type="protein sequence ID" value="PHX57105"/>
        <property type="gene ID" value="CP500_001490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="228"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="323" mass="36397" checksum="C4A0C6C5D770E536" modified="2018-01-31" version="1">MVTASAIESVPVTVLTGYLGAGKTTLLNRILTHEHGKKVAVIVNEFGEVGIDNQLIIDADEEIFETNNGCICCTVRGDLIRIINNLMKRRDKFDHIVIETTGLADPAPVIQTFFVDEDMRDKLLLDAVVTVVDAKHIWQHWDAEEVQEQIAFADVVLLNKTDLVTPEELTELETRIRNMNVMAKIHRTQNAEIEMSALLGVKAFDLNRALEIEPDFLGEHEHEHDETVTSVAIVESGAIDGDKFSDWIGELLRTQGTNIFRTKGILNIAGEDKRFVFQGVHMLFDGRQDRPWKATETPKNELVFIGRHLNATQLTEDFRKCLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F607</accession>
    <name>A0A2G4F607_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system HicB family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57202">
        <property type="protein sequence ID" value="PHX57202"/>
        <property type="gene ID" value="CP500_001390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031807">
        <property type="entry name" value="HicB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15919">
        <property type="entry name" value="HicB_lk_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HicB-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8581" checksum="13715012ADDCFBDD" modified="2018-01-31" version="1">MKYTIVIQWSEDDRCFVVFLPEFEDVMQPVTHGDSYEEAIYNAREVLELLIESCQAEGKPLPATKKLERLFQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F614</accession>
    <name>A0A2G4F614_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_002820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56927">
        <property type="protein sequence ID" value="PHX56927"/>
        <property type="gene ID" value="CP500_002820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021039">
        <property type="entry name" value="Fe-S-bd_prot_LdpA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12617">
        <property type="entry name" value="LdpA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="132"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="383" mass="41131" checksum="835F14293ABA5BB3" modified="2018-01-31" version="1">MTEHYHPLNSLKGGHWFKLICGASFQHLPAVRNLTLAYTLAGADCIDVAADPAAIAAAQEALQVASEIQAQTQNPRFGGKGLPWLMVSLNDGEDPHFRKAEFNPVECPADCWRPCEKICPAEAIIFQGAGEGVSGVIDERCYGCGRCLPVCPSQLIYTRSYVSAPAAIAPLILPYGVDALEIHTQVGRETDFARLWSSINPWVHQLKLIAISCPDGDGLIDYLRTLYQIISPLPCPLIWQTDGRPMSGDIGIGATRAAVKLGQKVLAAGLPGYVQLAGGTNAYTVSKLRASGLMKEHGKNLSIPDTPHIAGIAYGSYARFLLSPILEQLETMQIDRALAIPNAIAPPAAGAHIPGLTQLEAFPELLWQAVSLAHSLVSPLKEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F616</accession>
    <name>A0A2G4F616_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalamin biosynthesis protein CobW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cobW</name>
        <name evidence="3" type="ORF">CP500_001505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57165">
        <property type="protein sequence ID" value="PHX57165"/>
        <property type="gene ID" value="CP500_001505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012824">
        <property type="entry name" value="Cbl_biosynth_CobW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02475">
        <property type="entry name" value="CobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="254"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="342" mass="38541" checksum="4BB6D40C36E9F808" modified="2018-01-31" version="1">MHKIPVTVITGFLGSGKTTAIRHLLQNNQGRRIAVIVNEFGEVGIDGELLRDCQVCDDEGDAMTNIVELTNGCLCCTVQEEFLPTMQELLKRREQIDCILIETSGLALPKPLIQAFRWPEIRTGATVDGVVAVVDCEAIASGNFVGDIDALMAQRQADDSLDHETPIEELFEDQLACADMVLLTKVDRVDVETQKKVQTWLQQELRPSVKIVPCKGGEINPDVLLGFNAAVEDNLESRPSHHDTEEEHDHDDDITSTYFIADRDFEPDELVKKLQSLMQQQEIYRIKGFVAVPKKPMRMVLQGVGDRIEYFYDRAWKPSELRQTKLVFIGRELDSAKIQSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F638</accession>
    <name>A0A2G4F638_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="4">dUTPase</shortName>
            <ecNumber evidence="4">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dut</name>
        <name evidence="6" type="ORF">CP500_001840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57161">
        <property type="protein sequence ID" value="PHX57161"/>
        <property type="gene ID" value="CP500_001840"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00116">
        <property type="entry name" value="dUTPase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="5">
        <location>
            <begin position="12"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="62"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="79"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="15685" checksum="378B870A31BAFDA3" modified="2018-01-31" version="1">MKLKILQLHELAIIPKYAHESDAGLDLFSIDELEINPGESKLIHTGISIELPEKTEAQIRPRSGLALKHQITVLNSPGTIDEGYRGEIGVILINHGQTSFQVTKGMKIAQMVIAPVIRVEIEEVKMLSSSSRGDNGFGSTGISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6D6</accession>
    <name>A0A2G4F6D6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57353">
        <property type="protein sequence ID" value="PHX57353"/>
        <property type="gene ID" value="CP500_000810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="12658" checksum="28988D9A8DE801E9" modified="2018-01-31" version="1">MKLPNYERAVVPQKKITEYLLSLTHRDGKSKAKFFLRFSFSVDAWEIMATALVRHAADHELAKIEESPFGTRYVIEGEMLAADGRKPFVRSVWFIETGGDIPRLVSAYPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6F5</accession>
    <name>A0A2G4F6F5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">infB</name>
        <name evidence="11" type="ORF">CP500_000055</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57373">
        <property type="protein sequence ID" value="PHX57373"/>
        <property type="gene ID" value="CP500_000055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="560"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="35"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="178"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="417"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="101"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="569"/>
            <end position="576"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="619"/>
            <end position="623"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="673"/>
            <end position="676"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX57373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1065" mass="113541" checksum="82569DA366242583" modified="2018-01-31" version="1">MNNGKVRIYELSRELNLDNKDILAVCERLNISVKSHSSTITESEAERIRKTAEKYVASHSSPGKPAPPERAAAPSRESGPHPNDQQKKQQILEIRSPKVRPAGANSQQSGNEERKNPQATVATPPKSPAAQQIQSPPKPNINRPVLSKPTVPSATASSETLLEKVSDTVDAIASLETNTQAAVSIAPQVPSERAQRKERTRPPSPSAKLTSPPVRPAGESAVRANGDSPVRANGDSPVLGNKPVLKLAKTEQEQSERHDLEAPAKPSRPSRPALGAPESRDGQRPRPGGGPVKAQLADRPQPGGGPRRSLAPVTSAAGLRSRGGDSGIAGDDTDDNEEDNTPLETPLLERPSLPRPAKKTSVIWEEDDEENSDAAKAAKAAKLKQRSRLKPIDDDDDDLENGLDMPAPVMVSLSLARPAKSKSPAAPKSTPTPGAPGSSGKNKRPGPSHDKSSSGSTGGRGGRGGSKTAEAKVERPEKLYLSRPMTVQELAVTLAVPETEIIKRLFSKGIAVNITETLDIAAVRMVAEEMGIEVETPEKVAPALKVIDMLDATDLEYLQRRPPVVTIMGHVDHGKTTLLDSIRKTKVAQGEAGGITQHIGAYHVDVVHEGRSQQVVFLDTPGHEAFTAMRARGTRVTDIAILVVAADDGVRPQTIEAISHAKAAKVPIVVAINKIDKEGAQPERVKQELTEYGLVADDWGGDITMVPVSAIRGENLDTLLEMILTVAEMEDLNANPNRAAKGTVIEAHLDKARGPVATLLVQNGTLRVGDIVVAGSALGKVRAMIDDRGDRVEQATPSFAVEVLGLREVPRAGDEFDVFANEKEAGAIASGRATFQRDSRLLQGGRISLSGFSQQAKEGVLKELNLILKADVQGSLEAIVGALTQLPQKEVQLRLLLSAPGEVTETDIDLAAASNAVIIGFNTTLATGARQAADQAGVDVREYSIIYNLLDDIQGAMEGLLEPELVEEPLGSVEVRAVFAIGRGAVAGCMVLSGKVIRNCKVRVRRNNNVVYEGVLDSLKRMKEDAKEVNTGFECGISLSGFSDWADGDIIEAYRMVTKRRTLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6K7</accession>
    <name>A0A2G4F6K7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57388">
        <property type="protein sequence ID" value="PHX57388"/>
        <property type="gene ID" value="CP500_000150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="12"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="361" mass="41799" checksum="E2825D6507463044" modified="2018-01-31" version="1">MMPNKSLSWGLVIVTYKREKILPVCLELAIKQTRKPTEIIVIDASDDWETTRDTVMSEIAKNSSDIRWVYDRAEIPSITLQRNQGLQIATVDIVFLIDDDSLMYPTCAEEIMRIYEADPTSLVKGIQANGVDIPPSSDREIVDSQKTTGDTEKLARYENLRRVKDLLWENFFLMSTTKLFIPYDGDYPQYEIPSNLSHLNVITSPLFQGYRMTYRRETILQEKFEPLLRYYAAGEDLDASYRVSRQGMLLTAVNAKLHHFQSASGRLSRFKASALSALNQALFLRKYSSDLHRDRLVYYRLMARRIIAEICKDLLSRRWSLPQVRGLLVALKYAPKLFALPDEELAQWYTNLQREFLQLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6L9</accession>
    <name>A0A2G4F6L9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phycobilisome rod-core linker polypeptide CpcG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_000750</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the phycobilisome linker protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57341">
        <property type="protein sequence ID" value="PHX57341"/>
        <property type="gene ID" value="CP500_000750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001297">
        <property type="entry name" value="PBS_linker_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038255">
        <property type="entry name" value="PBS_linker_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00427">
        <property type="entry name" value="PBS_linker_poly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51445">
        <property type="entry name" value="PBS_LINKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="PBS-linker" evidence="7">
        <location>
            <begin position="11"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="28302" checksum="DF6B10FC0C6AD83E" modified="2018-01-31" version="1">MALPLLSYSPSSQNQRVAGYEVPGDEQPRIYTTENTLSPGEMDTLIHVAYRQICNEQQMLASNRQRFLESQLRVGQITVKDFIRGLAVSDSFRRLVYNSNNNYRFVQICIQRILGREVYSDREKMAWSIVLATKGLPGFIDDLLNSEEYLINFGEDIVPYQRRRILPQRSQGDLPFERMARYGIDYRNKLPQSSLRPIQRADGLFTQNERFDFATFVERANGPMVAALLLPVCGIIIVMLAIAIGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6M3</accession>
    <name>A0A2G4F6M3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FkbM family methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_000350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57422">
        <property type="protein sequence ID" value="PHX57422"/>
        <property type="gene ID" value="CP500_000350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1777"/>
            <end position="1798"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_21" evidence="4">
        <location>
            <begin position="177"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_21" evidence="4">
        <location>
            <begin position="425"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="624"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="2">
        <location>
            <begin position="1093"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="1306"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="1575"/>
            <end position="1733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1811" mass="206768" checksum="B9209163D166ACCF" modified="2018-01-31" version="1">MTRTNYDLNQIKADLERSKFKLQQIQTDLERSDFQPPQHQIKKDIEIEEYILQGQIDYQKLLTVLDDLVKQNLTDKAEGILSKILKQNNSNGEKLIEVLIGKGDWQTLWLMAQAAKKIGKINLVDKACAAVQSINPQFWFAREYPTHARGYYSQCEQDKVIEQFFLDYPPKNKIFVEVGACDGVHYSNVRRLYETYGWTGLCIEPVKRNFEKLAQSYQNTSVKCIRAAVGLEEGELDINVGINPDIPEWQSDVSTFLESETLRWQEEYGMLWEKEKVSIQRLTTILDKNGIPEIDFISIDTEGFDFDVLKSLDFSRFHPSMIVVEYGKDRQQIISYLAELGYSLLFDNGQDLFMVRLNHLFSEICPYLPATKAYTGATGNPPYAEIQQATENHLHEFIGKSANEVQCIVIVGGHLGFEIDRFLQNYSNAEIHVFEASQRYFSLLLERFAGSPRVFCHNYAVSEENGTAVFYETTLDGTGSLLPMKIQEDQDQGLTTFGASPAEAYTVATVTLDSFAPLAGKQIDLLWCDVQGAELKVLKGAKQTLERCSSLFLEVWLYRTMYQDQCQLSNLEKYLADHSIYLSGIGLNQSGGGEGNSFWLKGNQIHQKEILTVLNSKKKIVALIETKNESIQIAFCIRAVAKFVDAICVHDDVSDDNTVEIVESLRKEYPIERIIRKTESWQYSETGRQKPLLDAGREIGGTHFIFIDADEAFTSNLVENDFLRKEILKLNPGDRLQLAWIQLWRSVKQYRYDTSVWTNNYKQIIFADDGKCYYGDAAFHVGKMPLGLEGNLYTIEGYNYGLLHFQFVNWRNLLVKQAWYRCLEHIRQPQKSIQEINSTYGLSKDETNLGLRPCPNEWLSGYPFFDERIYKFPEQWREKQVLQWFKEYGYDYFSELDIWDIDWGNGIAELLPTPLSSFRDRKYHPSVTNSEFKDGCKILFYYAGFTNTSHIADGGAATAIISLATSLSKSYSYLSVEITGDHITKSHTYNGVKFLAFPQHEDREAFISKYDVVIFGAVIRTLLNIPKRSGQIWIFHHHCWYFEAEDTNRFNDLDAILCLSEIHRDAAISQGVPPEKTKICTNMVGDIFTPQPVARKKHSILFAGAIVSDKGLHVLLEALPIVKGIFPDAEVHVYGSAALWLDHSDSYEKDIKSVERNGVYFHGSVPRNRMPEIYSRYSILCLPSYLESFSLVSVEAQACGCIPVVHHVGGVAATLIDGKTGFLYSPNTEQELAKTIIKAFEKIDSDDSIRQVSATFAQESFSSYKIVEQLVSVLRTNLEDHQYSPVTFSRTSFPNTHYDRPHFKVSAIVSTYKSEKFMRGCLQDLVEQTLYQKGEVEIIVIDSASPENEQAIVREFQSKYPNIVYERTTEREPLYPSWNRAIKMLRGVYITNANADDRHRPDALEILANYLDTHLDTSLVYADQLISTVANETWLTNQATQRFSWPDFDYSELERQCICGPQPMWRKDIHNRHGYFRTDLIAAADYEFWLRIGKNEKLVHIPETLGIYYHNPDGLSTSGNAPVDEPIQIWAEYGISREGVSPVNVVVPISPSELNALPYRKIGQSTVNRSRPLVSVIIPTKDRPEMLAQAIQSVLNQTFTELEIIVVNDGGVDVQSVISRLNTRGNIVYKKHDRALERSAARNTGIRAARGKYIAYLDDDDNYYPNHIETLVKFLENSEYKIAYTDAVMAEQKKENGEYVTLHRSVPYSLDFDKDKILVSNCTPNLCLMHEKSCLDEVGLFDETLSTHEDWDLIIRLSRKFDIAISKKLPANLPKEMMALTPVAITALILLALGRLFLTNIASMQRLTPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Q7</accession>
    <name>A0A2G4F6Q7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hsp20/alpha crystallin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57438">
        <property type="protein sequence ID" value="PHX57438"/>
        <property type="gene ID" value="CP500_000440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045045">
        <property type="entry name" value="RTM2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43670">
        <property type="entry name" value="PTHR43670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="33"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="146" mass="16591" checksum="253400853BB8943E" modified="2018-01-31" version="1">MTLIRWEPLREMDSLQREMNRLFDSLTPTVDRTSNAVAFVPLAEMHETPDAIHLKLEIPGMESEDLDVQVTAEAVAISGERRSETQASEKGLTRSEFRYGSFRRVIPLPTRIQNDNVQAEYKNGVLNLNLPKAEVEKNRVVKVQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUF4</accession>
    <name>A0A2G4EUF4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000252">
        <property type="protein sequence ID" value="PHX53173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53173">
        <property type="protein sequence ID" value="PHX53173"/>
        <property type="gene ID" value="CP500_022910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="7290" checksum="164C11023905C98E" modified="2018-01-31" version="1">MNSLSNSESPLKRTNEFFSPLKRTFALRQGFQPLSDYRFYLKLTLLGHCRVLISATLETSYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUF8</accession>
    <name>A0A2G4EUF8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_022850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2Fe2S plant-type ferredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000249">
        <property type="protein sequence ID" value="PHX53182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53182">
        <property type="protein sequence ID" value="PHX53182"/>
        <property type="gene ID" value="CP500_022850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010241">
        <property type="entry name" value="Fd_pln"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02008">
        <property type="entry name" value="fdx_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13813" checksum="5C17BAFABC83AA58" modified="2018-01-31" version="1">MTRSYTIKIHNRKTGSRHTVTVPENRYILQNVENQGVELPFSCRNGACTACAVRVVSGELHQPEAMGLSPELQKQGYALLCVSYARSNVEVETQDEDEVYELQFGRFFAKSKVRFGLPLDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUT1</accession>
    <name>A0A2G4EUT1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium:calcium exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_022815</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000247">
        <property type="protein sequence ID" value="PHX53190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53190">
        <property type="protein sequence ID" value="PHX53190"/>
        <property type="gene ID" value="CP500_022815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="416"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="580"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="672"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="771" mass="83609" checksum="6893DE37578889D5" modified="2018-01-31" version="1">MQEDFRLIVDLVLVLAAAAAGGLFASLLRQPVILGYLLGGMVVGPAGLGLIKELIQVETLAEFGVAFLLFALGVEFSFTELQKVKAISLGGGSLQIVLTIAITTFTSLAVGWVESPAQGVFLGAILSLSSTAVVLKCLMERNEAGTSHGQVMLGILVVQDLALGLMLAVLPALNQPAEAIGITIAFALLRISLFAAGAVVAGIWVIPRLLRYLARTESRELFLLGVVVLALGIALLTEYLGFSIEMGAFVAGLMISEVEYADQTLTYVEPLRDIFASLFFVSIGMLIDPFFLWNHLELILGLVFLVFVGKFLIITPIVRLFGYPLKTALIAGLGLAQIGEFSFVLASSGQALGLVSRNVYLLILGTTAVTLVLTPFVLRSVPQLLKWAENFGPLRRYFDTTSQAVEIAETLPEQNHIVICGYGRVGRNLVKMLLSRNCAVVVIDESESRIQECRTQGIPYIYGNAASRHVLEAAGVQRAKAMAVTLPDPMSTRLCLKRALELVPDLDIVVRANQDKDIELLYQLGAWEVVQPEFEASLELSSHLLAGMGLSAIAIGREVQQIRSNRYLELLPARGNSAISRDLQVAVQDMNSKWYSLPEGSPIASMTLEETNLRQLTGVSVMAIVRQEGAEIDYPNGKTALESGDRVLVVGEPEELISFELLAKGEVAVPPGDSSCQWLRLPANSPWVGQKLSEVELLTQYAVEVRAIRREGKFTRWPEGSTDLQEGDRLLLCGGFYEIGLMQRTAAPVVQPPVVKLPFVTAQVSEKLFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV33</accession>
    <name>A0A2G4EV33_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000204">
        <property type="protein sequence ID" value="PHX53391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53391">
        <property type="protein sequence ID" value="PHX53391"/>
        <property type="gene ID" value="CP500_021770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="6769" checksum="0DBEBD552B48773A" modified="2018-01-31" version="1">MHGQAKLLITHNVSVNCNLSNTDFEFEKVVFGNLLLKTQISAPGISFSTFVMVILARSEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV59</accession>
    <name>A0A2G4EV59_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-Ig-H3/fasciclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000208">
        <property type="protein sequence ID" value="PHX53368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53368">
        <property type="protein sequence ID" value="PHX53368"/>
        <property type="gene ID" value="CP500_021865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="65"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="202" mass="20406" checksum="187B806865B1E797" modified="2018-01-31" version="1">MKNSNLPSWMKQLTGFAGVIGASALIGFPAWAHINANTSVANAATTQQVAGNAKTAASPAPTAQAKDIVAIASGDPQFKTLTTALKAAGLVQTLQGKGPFTVFAPTDAAFAALPKGTLEDLLKPANKAKLTKILTYHVVSGSVLSTSLKSGDVPTVEKSPVKVVVSGGKVTVGGANVVKADIKASNGVIHVIDKVLIPGDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV91</accession>
    <name>A0A2G4EV91_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aldehyde-alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000196">
        <property type="protein sequence ID" value="PHX53449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53449">
        <property type="protein sequence ID" value="PHX53449"/>
        <property type="gene ID" value="CP500_021445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008774">
        <property type="term" value="F:acetaldehyde dehydrogenase (acetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08178">
        <property type="entry name" value="AAD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034789">
        <property type="entry name" value="AAD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012079">
        <property type="entry name" value="Bifunc_Ald-ADH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000111">
        <property type="entry name" value="ALDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="9"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-ADH" evidence="4">
        <location>
            <begin position="458"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="870" mass="95120" checksum="AD67BC72AE3B0848" modified="2018-01-31" version="1">MTMKVTNIDELKLLIENVKAAQAEFATFTQEQVDRIFKQAALAANAARIPLAKAAVKESGMGVIEDKAIKNHFASEMIYNKYKNDKTCGVIESDKHFGYERIAEPVGLLAGIVPVTNPTSTTIFKSLIALKTRNGIIFSPHPHAKECTIAAAKIVLDAAVAAGAPRDIIGWIDEPTVPLSQALMQNPDIKLILATGGPGMVKAAYSSGHPSIGVGAGNTPAIIDETAHIQMAVSSIILSKTFDNGTICASEQSVVVVDAVYESVRQEFIKRGAYFLNAEERDRVRQVILTDGHLNPKIVGQTVSKIAEVAGLEIPGNTRVLIGEVEAIDKDEPFAYEKLSPILAMYRATDFHDAVEKAEALILFGGHGHTSALYTAPSNQEHIRYFENKVETSRVLINTPSSQGAIGDLYNFRLDPSLTLGCGSWGGNSVSANVTPHHLLNIKTVASRRENMLWFRIPPKIYFKFGCLPVALRDLAGKKRALIVTDRPLFELGLTKEVTESLEEIGIAHYTFYDVEPDPSLATVRKGLAICNSFHPDVIIAFGGGSPMDAAKVMWLMYEHPDIEFEGLAMRFMDIRKRVYELPPLGEKAMMVSIPTTSGTGSEVTPFAVVTDEKSGIKYPLADYALTPNIAIVDPELTMNMPKRLTAYGGIDALTHAIEAYVSVLASEYTNGLALEAIRLLFKYLPSAYKNGAKDPKAREKVHYAATIAGMAFANAFLGVCHSIAHQLGGNCHIPHGLANALMISHVIRYNATDVPFKQATFSQNKYPNSTWRYAQIANYLNLGGETDEEKVEKLIEAVEELKRQVEIPATIQEVLLEQGVADDFFFAHVEEMADRAFDDQCTGANPRYPLIADLKQLLIQAYLGEGMTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVB6</accession>
    <name>A0A2G4EVB6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000192">
        <property type="protein sequence ID" value="PHX53481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53481">
        <property type="protein sequence ID" value="PHX53481"/>
        <property type="gene ID" value="CP500_021320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="242" mass="27216" checksum="3FB3ECEDB5D33F11" modified="2018-01-31" version="1" fragment="single">MRILMLSSTFPYPPSRGGTQVRTFNLLKYLSQRHDVILGTLRSPDVTDVQIDELRQQVAELAVFPNPQIPPQPPLGKGGLRLHQQLDGDFLPPPLSKGGTEGGFYGIIGKLHRFSQFLQSGTPPNVLSRYSPAMQHWVNELVTAGKCDAITCEHSVNEIYVRPEWRQNLLTVVNIHSSVSGTCKQMLETGTSENPLRDRLNLPLLVHYEKRYCAKFSRIVATTEIDKQQLLELLFGEGERGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVH9</accession>
    <name>A0A2G4EVH9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="4">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="4">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truB</name>
        <name evidence="8" type="ORF">CP500_020995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000182">
        <property type="protein sequence ID" value="PHX53534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53534">
        <property type="protein sequence ID" value="PHX53534"/>
        <property type="gene ID" value="CP500_020995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015240">
        <property type="entry name" value="tRNA_sdUridine_synth_fam1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09157">
        <property type="entry name" value="TruB-C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="6">
        <location>
            <begin position="24"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="TruB-C_2" evidence="7">
        <location>
            <begin position="236"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="313" mass="34394" checksum="4D92AC0B88ACF227" modified="2018-01-31" version="1">MYEGFLNLNKPAGMTSHDCVGRVRRLLKLKRVGHGGTLDPTVTGVLPIALGKATRLLQFLQYHKAYKGTIRFGLTTATDDLEGEILSSQSVPDLTLEKVQTELPNFIGKIEQFPPSFSAIQVGGKRLYELARKGETVEVAARKVEVFRLDVLDWRAGDFPELDLAISCGAGTYIRAIARDLGAILNVGGTLACLTRTESSGFAIEHSLSFADLEMQLQEGKFSPIPPSEVLGHLGAIVLSSEYTKRWFQGQRLPIPETPQKEREEASRNELSQTPSPLSPYFLQVYNEDGQFLGIGQVANSDTNTILSPQIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW04</accession>
    <name>A0A2G4EW04_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4258 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53699">
        <property type="protein sequence ID" value="PHX53699"/>
        <property type="gene ID" value="CP500_020060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025354">
        <property type="entry name" value="DUF4258"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14076">
        <property type="entry name" value="DUF4258"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="93" mass="10699" checksum="E2E3E3C9DC47B996" modified="2018-01-31" version="1">MFDKILRMIREKVSNQHYVMTLHAEEEMEDDDLIIYDIEQGILTGKILECQKDRVTAESKYRIRGETTDGGEVELIVKLSPTGKVVIITVYVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW14</accession>
    <name>A0A2G4EW14_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53723">
        <property type="protein sequence ID" value="PHX53723"/>
        <property type="gene ID" value="CP500_019975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018334">
        <property type="entry name" value="ArsR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00846">
        <property type="entry name" value="HTH_ARSR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="42"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="15029" checksum="DA6F825371D525AA" modified="2018-01-31" version="1">MSPKSAVKGAGNQSIAQNDTPMCDRPHLVDSLRTEGIQTQVLNTAKAQRMAEFFSLLGDANRLRLLSVLAKQELCVCDLAATLSMSESAVSHQLRALRAMRLVSYRKVGRQVFYSLLDRHVLELYNAVAEHLDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW50</accession>
    <name>A0A2G4EW50_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nucleoside:proton symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_019745</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53749">
        <property type="protein sequence ID" value="PHX53749"/>
        <property type="gene ID" value="CP500_019745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_N" evidence="8">
        <location>
            <begin position="10"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="9">
        <location>
            <begin position="210"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="467"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="517" mass="55104" checksum="B80FA5D3DE08381C" modified="2018-01-31" version="1">MSIYNFISFLGIFGLCAIAWIFSENRQRKYIPWRVIIWGIGLQLVLGFLVFLFPPTRIALEWFTSLLDSVFTAADTGARFVFGKNIVPIPGQDSPVNLGYIFAFRALPTVIFFSGLMALLYNIGVIQIVTELFAKIFYKTMRLSGAEALSGAANIFVGIEAAIVVKPYLPQMTRSELCAILSCCFGTAASSTLAIYVSFLKPVFPNILGHLVSASIIAIPACFVLSKILVPETGVPLTMGGIPKEKPKPQGREFVGEEIDGEIRQQETVGGEPIERVSPLDAAIIGALDGVKMAVAIAAVLILILGLVSLINQFFGWLAILPNPIGGVFKVVTLANIMGFLFYPLTLLTGVPLEDSWQASIIIGRRLLETAIPPYQTLAEVAGKGLISDRTVLIVSYALSGFAHLASVGIFVGGTIALIPSRRKDISELGWKALFVGTLATMMIACIAGLFDTGDASILGTKAAPAAPLTAPGSPKPVATSKPSVAPQIANPKPSPKTEKAVPKATKSPSPESKKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWC2</accession>
    <name>A0A2G4EWC2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000158">
        <property type="protein sequence ID" value="PHX53740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53740">
        <property type="protein sequence ID" value="PHX53740"/>
        <property type="gene ID" value="CP500_019845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7648" checksum="F18A49D25C7F0C1B" modified="2018-01-31" version="1">MSELISLALLIAYGAGIWKFWNGFDRTNFDRSFPNRLKLALLWPALIFNKPYRQNFTKALKASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWI0</accession>
    <name>A0A2G4EWI0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arogenate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000143">
        <property type="protein sequence ID" value="PHX53893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53893">
        <property type="protein sequence ID" value="PHX53893"/>
        <property type="gene ID" value="CP500_019050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="281" mass="29973" checksum="98690A0A5DA72634" modified="2018-01-31" version="1">MNIGIVGLGLIGGSIGLDLRSRGFDVFGVSSREQTCQRAVALGVVDAASVNLSDMAVADVVFICTPLGSIESIAQKLVPHLSPDTILTDVGSVKTPIVQPVSSLWPNFVGGHPMAGTAESGIEAAVRDLFVGRPYVVTPTAETPMAAVERVEEIARSLGAKVYRCGPEEHDRAVAGISHLPIMASATLVAACAQEGDRDIVKLAQHLASSGFRDTSRVGGGNPELGVMVARYNRVELLRSLSIYRDCLDEFISDIEAEDWQALEQKLKLTQEARRSYDLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWQ9</accession>
    <name>A0A2G4EWQ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000173">
        <property type="protein sequence ID" value="PHX53607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53607">
        <property type="protein sequence ID" value="PHX53607"/>
        <property type="gene ID" value="CP500_020570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="53"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="304" mass="34315" checksum="54AD04FB03E3ED20" modified="2018-01-31" version="1">MEISLSSVVATPFDDCPQPSESIQGIDDFVVQFWGVRGSVPTPGSETLRYGGNTSCLEMRVGGKRLIFDGGTGLRMLGDQLLQEMPVQAYMFFTHYHWDHIQGFPLFAPAFIRGNRFDIYGATPPGGDCLKRHFVERVLHSNSPVPLMGLPADLNFHELHHNQTMMLDDIEIRTGSLNHPNTAMGYRVTWQGRSVVYCSDTEHFPDRLDENIYNLALDADVLIYDAMYTDEEYHNPKSPKIGWGHSTWQEAVRMGKEARVKRVVIFHHDPAHSDDFLDRIAEEVQVASPKAVMAREGLILQIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWU0</accession>
    <name>A0A2G4EWU0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5 8">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 11" type="primary">clpP</name>
        <name evidence="11" type="ORF">CP500_018360</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 9">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 10">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5 8"/>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54003">
        <property type="protein sequence ID" value="PHX54003"/>
        <property type="gene ID" value="CP500_018360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00493">
        <property type="entry name" value="clpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0720">Serine protease</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="202" mass="22271" checksum="8B77F37A4B38DF0F" modified="2018-01-31" version="1">MIPTVIEQSGRGERAFDIYSRLLRDRIVFLGQQVDSDLANLIVAQLLFLDAEDPEKDIYLYINSPGGSVTAGMGIFDTMNHIRPDVCTICLGLAASMGAFLLSAGAKGKRMSLPHTRIMIHQPLGGAQGQATDIEIQAKEILYHKRRLNGFLADHTGQPLSRIEEDTERDFFMSAEEAKDYGLVDQVIDRRPSAIRPIAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWY6</accession>
    <name>A0A2G4EWY6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000130">
        <property type="protein sequence ID" value="PHX54039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54039">
        <property type="protein sequence ID" value="PHX54039"/>
        <property type="gene ID" value="CP500_018250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="305" mass="31836" checksum="1769EFD005A61D1D" modified="2018-01-31" version="1">MLETNLGEIRALAEISSPIIPDPSNIKLLTGPLPNQGDPNFFDLTANDDVVLLANGILRNTPGGLRALSGNDFVRGSGAAELINGNSGRDTLIGGCGNDTIRGGQDSDIIYGECGNDIISGDRDDDYAYGGTGNDFLRGGKGNDALVGESGNDTLTGDAGIDRLWGGEGSDLFVIRRESGATSREFGSDQPRPVGTFPSNVEQVPADFILDYNPSQGDVIGLAGGLTRNDVILTERFLTIGDARDYDSSGPIPPGSIITTEFRILNTKATVIREASTGNILGLVKDVSPSQLQFTSVSDSAIGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX85</accession>
    <name>A0A2G4EX85_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1768 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_017990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O = 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23436"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:137796"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-amino-6-(5-phospho-D-ribosylamino)uracil + H2O = 5,6-diaminouracil + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:55020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:46252"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54088">
        <property type="protein sequence ID" value="PHX54088"/>
        <property type="gene ID" value="CP500_017990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="SSF143990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02464">
        <property type="entry name" value="ribofla_fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="3">
        <location>
            <begin position="5"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17576" checksum="3E84A5EDFBC88C54" modified="2018-01-31" version="1">MTNNFYKVDEPYGCFSNFSLHNICINGQNWLTVEHYYQAQKFVGSADRSLVAAIRAVPTPQEAANLGRNPKHCVRADWEVVKISVMSEAVKTKFITHTDIQRILLDTADRLIVENSPTDYYWGCGCNQTGHNHLGQILMSVRREISESLAKSEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX93</accession>
    <name>A0A2G4EX93_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53767">
        <property type="protein sequence ID" value="PHX53767"/>
        <property type="gene ID" value="CP500_019650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7700" checksum="5B3300C33182B22C" modified="2018-01-31" version="1">MFRDFAVGLKIKIIKKGAISSMENIEKVLEQIQEWVRKLIEGLMNPEPQPELIPIPVPVNQPRHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXC3</accession>
    <name>A0A2G4EXC3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_019600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000154">
        <property type="protein sequence ID" value="PHX53797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53797">
        <property type="protein sequence ID" value="PHX53797"/>
        <property type="gene ID" value="CP500_019600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="PTHR31632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="320" mass="34511" checksum="4119DB9F81402018" modified="2018-01-31" version="1">MNFTEAIPTFAITLREGVEAALVVGIVLACLKKAEQTHLNSWVYTGIGAGIAASAFVGALFNQLLYALSTSNQPYAPVIKQLLEGCLGIFAIVMLSWMLIWMTQQSRFLKAEVEGAVTAALKSNTNAGWGVFGLIFIAVLREGFETVIFVSSQFQQGLTPALGAVGGLLGAAIIGSLIFKWGVKIDIRQFFKFMGILLLLIVAGLAVSALKHFDQAAAILSQIDSNYAAICVYFDRTAQLHSCILGPMVWNAAGILPDREFPGILLKALFGYRDRLYLIQAIGYITFLATIGNLYFQKLGGKATVSSKNTQPTQETTIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXH0</accession>
    <name>A0A2G4EXH0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_017545</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000118">
        <property type="protein sequence ID" value="PHX54176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54176">
        <property type="protein sequence ID" value="PHX54176"/>
        <property type="gene ID" value="CP500_017545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016205">
        <property type="entry name" value="Glycerol_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43616">
        <property type="entry name" value="PTHR43616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000112">
        <property type="entry name" value="Glycerol_dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Fe-ADH" evidence="6">
        <location>
            <begin position="22"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="103"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="376" mass="39809" checksum="117C9506DCA3B7FC" modified="2018-01-31" version="1">MTHTSTATKTATAILSLTIAPACVIRGQNAIARSTEAIARLGKRPLIVGGKNSLAAIQPYLQNQQLQAAQATYGKDCSENSLKTLHEAAATHKADFIIGVGGGKALDAAKLLAHQCQIPIATIPTSAATCAAWTALSNIYSEQGAFQYDVTLAKCPDLLILDYGLIQTAPQRTLVAGIGDAIAKWYEASVSSGHSEQTMIISAVQQARILRDILFQKSAIALKEPGSETWQEVTDAVVLLAGVIGGIGGAQCRTVAAHAVHNGLTHLLASHGTLHGEKVAYGILVQLRLEEMLQNNQLAATARQQLLKFYTEIGLPQTLDSLGLGDITITELQRAAEIACSPNSDIHRLPFKVVPEQLMAAMVSTTAPVGELRVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY41</accession>
    <name>A0A2G4EY41_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TldD/PmbA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_016130</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000101">
        <property type="protein sequence ID" value="PHX54439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54439">
        <property type="protein sequence ID" value="PHX54439"/>
        <property type="gene ID" value="CP500_016130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025502">
        <property type="entry name" value="TldD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004919">
        <property type="entry name" value="TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="3">
        <location>
            <begin position="28"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="5">
        <location>
            <begin position="117"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="4">
        <location>
            <begin position="231"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="467" mass="50506" checksum="3BE5A7967E409BD1" modified="2018-01-31" version="1">MPTSIADSKNLLSDLMARYRHQVDYLAIRLEEAEGTDILLRGEKIETLSEGVSIGGQVRACHKGGWGFASFNRLSTLAERIEEAIAAAKLIGEEETILAPVTPVQDICFLPLTGTDPRLVPLIEKKQLCDRYAQILRSIDPCIATVSVRYGDSTQRIILATSEGTMLEQGWVDMEMRFAATARSGETVQTGRETTGSRKAYEDLTDLDVQVRSAAQRAVDSLALPPVQGNTYTVVIDPILSGLFVHEAFGHLSEADMAYENPDILEVMTLGRQFGPKDLQIFDGAAPPGHRGSYFYDDEGTPATTTQLIKDGALVGRLHSRETAGKLGEVPTGNARCLNYHYPPIVRMTNTWIERGTTPVADLFSGISEGVYASNWQGGMTNGEMFTFSAGEAWMIRDGKLAEPVRDVTLSGNVFSTLADIEAIGDDFYWDESGGCGKGGQSGLPVGCGGPSLRIRNVVVGGEAAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY95</accession>
    <name>A0A2G4EY95_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000097">
        <property type="protein sequence ID" value="PHX54491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54491">
        <property type="protein sequence ID" value="PHX54491"/>
        <property type="gene ID" value="CP500_015870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="201"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="388" mass="43469" checksum="44E1B5880B40FFA0" modified="2018-01-31" version="1">MVDRGDLRVAWLVPEVELGAYWQPVLREFTKVFKNTVFYTGRVWSGFDPTLPGASAIKLVGETKFVETEKIETGYDRGFIAVSPSIIGHLLKFRPQIVFPQAFSLWTVLVVLLKPLGGWKIAIIYDGSSPNTDFRDSSFRTFVRRILAKFADAFVSNSQAGKRYLVEALNVPETQVFTKTYLVPDAETLLKPLSGNKVEKLGLKQPIFLYVGRITARKGIKTLLEACALLKKQGYSDYTLLIVGKGDQQEELESFIREQDFSAQVKWVGWVDYGSLGTYFDQADIFVFPTFEDVWGMVVPEAMVFGKPVLCSNGAASCELIAEGENGYIFDPNNAQELAIKMQVFIDNPNLVESMGERSRHLISQKTPETAAKAYVEVISFLMKSVNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYH5</accession>
    <name>A0A2G4EYH5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="2">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">carA</name>
        <name evidence="4" type="ORF">CP500_015520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54561">
        <property type="protein sequence ID" value="PHX54561"/>
        <property type="gene ID" value="CP500_015520"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="3">
        <location>
            <begin position="7"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="384" mass="42087" checksum="0454A133AFEC841F" modified="2018-01-31" version="1">MSLSTAQPALLVLADGTAYRGWSFGARTTVVGEVVFNTGMTGYQEVLTDPSYSGQIVTFTYPELGNTGVNLEDQESSRPHIRAAIARNVCDRPSNWRSSQSLPDYLKQYNIPGIYGIDTRALTRKIRTVGAINGGISTSILDPAELLEQVQDAPSMDGLNLVREVTTREVYEWSEATDSVWEFSPTVKPANGEMWTVVAIDFGIKRNILRRLASYGCRVIVVPADTTPEEILKYNPDGIFLSNGPGDPSAVTEGIETAKALLKSDKPVFGICMGHQILGLSLGAETFKLKFGHRGLNHPAGLTQQVEITSQNHGFAIDPDSLVPEVEITHLNLNDRTVAGLKHKTLPLFSVQYHPEASPGPHDADYLFDRFVQSMRENQKVAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYH8</accession>
    <name>A0A2G4EYH8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_015310</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000090">
        <property type="protein sequence ID" value="PHX54579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54579">
        <property type="protein sequence ID" value="PHX54579"/>
        <property type="gene ID" value="CP500_015310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="109"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="172"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="452"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="9">
        <location>
            <begin position="631"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="569"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="770" mass="86181" checksum="77AD814E15F74A9D" modified="2018-01-31" version="1">MNINKQIQDQKGCRKPDRADRSRNMNITKGIDSSLQECLDFKAAIDRSTLAVRTNGKGIINYVSDRVCEISKYSRIEILGSHFGILHWEYQSSELIRNLQSTLTKGEIWQGEVKTLAKDGSDYWVHAVIVPFLDFKGKPYQYLAIGFDITECKAIAVVQAEANRTRDEFLAIASHELRSPLSVILGWVQLARSGKLNEGITSRALEIIERNAKLQNQQIDNLLDLSRLLRGKMNLNMGQVHLPSVIESAIDILRPAADAKNIEIVTNFDPAISYILGDAERLQQVVWNLLSNAIKFTPTSTSAVIQIAIESTPLGALILVGDSGCGIEPKFLPHIFDYFRSTDSWNTNEQNRLGLGLFIVRQLVELHGGTVWASSLGIAQGTTFGVQLPIGNYQDVLDDRNSAIGQMENRAESLCQACAGKQMLVVDDNVESKNSPNWVEDKLVDDSRDLPLLLVVEDNYFLLVYLETLLTPHYRVAIARDGVEGLEQAKKLLPNLILSDQIMPRQNGLDLLKEIRNTPELSSTPVIFLTARMGMEARIESLDAGADDYISKPFDERELLARVRNLLRSHAAEQQLVALNRQLQQQKQQLETVNQALEYLATYDSLTEVKNRRCFNEYLDTEWWRLAREEAPLSLIMCDIDYFKLYNDTYGHQAGDECLRQVASVLRSAVKRPADLVARYGGEEFAVVLPNTDIEGAARVAEFIRAEVRGLQIVHAKSVVCEYVTLSLGVACCIPLPMSQPGTLIAIADEELYRAKKTGRDRVSVATFQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYK2</accession>
    <name>A0A2G4EYK2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF565 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ycf20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54591">
        <property type="protein sequence ID" value="PHX54591"/>
        <property type="gene ID" value="CP500_015240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007572">
        <property type="entry name" value="Uncharacterised_Ycf20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33787">
        <property type="entry name" value="PTHR33787"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04483">
        <property type="entry name" value="DUF565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12572" checksum="522E95FE77F4C38F" modified="2018-01-31" version="1">MQNTRINRFIDVLAEQFRRWLSNPWRRISLWVITLLFGNFLGTAISTIAGQSANWDIVAAAWLIVLTELVNRFVYGSNQPAVRSLWVDILNALKIGVTYNLFVEAFKLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYK3</accession>
    <name>A0A2G4EYK3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="7">GPR</shortName>
            <ecNumber evidence="7">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="7">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proA</name>
        <name evidence="9" type="ORF">CP500_015465</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54550">
        <property type="protein sequence ID" value="PHX54550"/>
        <property type="gene ID" value="CP500_015465"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="16"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="421" mass="46536" checksum="51778F77A457CA13" modified="2018-01-31" version="1">MIIDDSKPLPDSANVARCAYQASLELAGTKSTDRAAALQMMASVLKRRQNDILEANTLDLEASRDMAIPELIVDWLKLTPDRIKTTVQILERLGEMPDPIGRVINASYQVDRCQVYCQSLPLGAIALIYEAFPELGAIAAGLCLKSANSLILKGGSESWQTNAVIGEALQSAIDEVGLPSGCLQVLPPDRGASIRDLVTQDQYLNLIIPYGRPSLVQQVVRQCTVPVLRSAMGNCYLYWSPTGSLEMARWMILDSHQSVPDPVNAIEKVLIDRNQKPSSLVRLWNILKEKGFQIRGDAELVADFPDLKLAEPSEWTQPYLNKTIAFKVVDSLESAIGWINRYSSGHADSIATESYLESRQFALDVNSASTFINASPRFWRYQNRGDAIFLGMSNQKGYRRGLIGLDTLTTIKQIVQGNGQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYM6</accession>
    <name>A0A2G4EYM6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54277">
        <property type="protein sequence ID" value="PHX54277"/>
        <property type="gene ID" value="CP500_017045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8029" checksum="70341499AB59EDF8" modified="2018-01-31" version="1">MEVSDTGKGISPEFLPYVFDRFQQADLVDTRSNNRSGLGLSIVRYLVEAHCGAVRAESAGLGKRATFTVSLPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYY5</accession>
    <name>A0A2G4EYY5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54688">
        <property type="protein sequence ID" value="PHX54688"/>
        <property type="gene ID" value="CP500_014825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="852"/>
            <end position="1210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1211" mass="136661" checksum="D7A0FF844F8CC949" modified="2018-01-31" version="1">MDEQRRKTDINMLQALLENPGDSGTELILKLNSESISIDSESVEILYLEVPALTPESLVKAAKFFQRVIAPLELARENAPLPVTPQAYLTFLAEILQTVTHSPDFRQVYPLLRNNLDKLDQNFAQLLRQWASSVMPGATSVETRRLGGLIGNLSHAIGRFPLGNKANNLEIEIAGYETVAKVFTRSNFPQDWAMLQNNLGNAYSDRRQGDPAQNLDTAIACFKNALQVRTPQEYPEQWATLQNNLGNAYTDRRQGDPAENLEKAIDCYQNALRIRTRETFGEEWASTQNNLGRAYSRRIRGDRPQNLELAIACYYNALQIYNRNLFPRRWATTQNNLANAYCARLRGNRAENLEYAINCYQRALQIRTREAFPVQWATTQSNLGRVWIDRIKGDRIENLEMAIACYQNALQVHTCQKFPDRWATLQTYLGKVYNLRLKGEKTDNLELVIACYQNALLFCNRQKFPERWAILYAYLGRALSEHHKGERSGNLKSAIACYQNALKVYTRNKSPDRWAMLQNDLGQAFCELTETENSSHLQTAIACYHNATKVYTRETYPHRWAQTLFYLGKAHRIQGELLLAYSVFAAAVDTVEFWRCEATIDLVDLSASAIANSLKSTRTWTGLYKSLVQVCLELGTTQPEYYAKALEYTERHKALNLVELLMKCDLTPKGDIPPVVRGELECLRRSIVAEQQHQEQGVSEAGSVISAGDDTQGLNGGSLLGNSDWTHLNQLWKQLDELIASEVESKDPFFNLARQVQPIGFKQIRELLPDANCAAVVWGSFGEVLVAFVVLADAEYPVVHLCSPKNALELESWAFEYKSAYSDQKGRWTNHLQARLNRLATLLEIDQVVSMVPENCDRLIFVPHRFLHALPLHALPLGMGQLFFEHQGNSRFPGLDRIGSDLDTLIGSDFSQVSAVNNLQPPAAYLIDRFAGGIRYAPSCQILRLKQIEHSGAIGRYRPRLQQLIGVPNFTKDSLYSNIEVSNICQYFSTAEVLHHKQVNKEAICSAVTANNYGDSPVPTGQLISKKVAHFACLSLLNLASPLKSGMSLTDNFLSLDEIFNLDFRQYFLVTLSACEIEKAEVTNDGDFVGFSAALLYAGTSSVVSSLWKVNDISTLLLTSKFYENLARFPRLQTGDVAHALNDAQRWLRDLTGEELDQLLADFQPQISQIFDRLTQSSRLIAEASFQQIRNRKPHPFANPYYWAAFTASGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ29</accession>
    <name>A0A2G4EZ29_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General secretion pathway protein GspD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_014285</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the bacterial secretin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54750">
        <property type="protein sequence ID" value="PHX54750"/>
        <property type="gene ID" value="CP500_014285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021731">
        <property type="entry name" value="AMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11741">
        <property type="entry name" value="AMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013948778" evidence="8">
        <location>
            <begin position="28"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="STN" evidence="9">
        <location>
            <begin position="270"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="134"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="780"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="806" mass="84736" checksum="087C0AF5FF4AA09B" modified="2018-01-31" version="1">MKQHLRLTGGLLSTVAGVLVAQAPVWAVPTQVTGVQVSQVNNGVNIVLATEKGDRPQVFAINNGNTYQATIINTQLRLPQGKAFRQENPAPGISSVEVTPVDANSIRVMVTGTNGVPSGQILQGQGSGIVLSVSRQGGTPQSTQAALPGSPRLNQTAPPPPGLPLSQTAPVPAPQIRTAQNPNVMLPNPEITITRNDRPPLPSEIQSQANQAPPFQPRAVAPPLGDISVSNIAPGAGNIELSSGERIPRLVLRDAPVRDVLALLARAASLNIAFTGGGASAQPGQPAAAAGAAGGSDEGPKISLDIENESVQDVFNYVLRLSGLQANRVGRTIFVGANLPIDSRNIIVRTLRLNQVRSTDAANFLSAQGAETQLPITRVTIQTVGQGNAARDVEIREPDIKAIGAKDGNGPLLLRGLSVLADSRLNSITLVGDPRKVDLAVGFLTQLDLRRRQVAVNVKVIDINLLGDNRSNSSFSFGINNNFFVNDGGSASLNFGGLQPATGGDVANGSRTTPPIVPNPFSGIDPVYDANGRITVPLTGQGVNGPGKGVFLRPTAPITNDPRRVAITDYEPGSATTSGTATFGLFPLLQYPKRFLSALQASITTQNAKILTDPTLVVQEGETANVNITDEVISNVTSQTQTTGNTSTTTVTVIKDKSGLQLGVAIDRVDDNGFVSLRVNPVIRVVGPAQALVNTGQNSNTISLLSERSLQSGLIRLRDGQTLIISGIISDQEKVTAKKIPILGDLPIIGSLFRNTTKSNQRAEVIVLLTPQILDDSDRSNFGYQNNIGPDARQLLQRSQPVQPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZB8</accession>
    <name>A0A2G4EZB8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_013805</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54852">
        <property type="protein sequence ID" value="PHX54852"/>
        <property type="gene ID" value="CP500_013805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17684" checksum="95895E299FA6654F" modified="2018-01-31" version="1">MKDEAFGIIPVFSTESDLLFLLIQHQAGHWAFPKGHADPGESALETAKRELEEETGIRDYEVLEEPSFVEHYSFVQESVPSSVKHYSFAKEGELIEKTVTYFVAFVNSMEVVLQAEEVQNYAWSSFDEAINLITFDGNRGILREVKVYLDGRKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZD1</accession>
    <name>A0A2G4EZD1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cysE</name>
        <name evidence="7" type="ORF">CP500_013840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54859">
        <property type="protein sequence ID" value="PHX54859"/>
        <property type="gene ID" value="CP500_013840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="243" mass="26160" checksum="E43929A344D070B4" modified="2018-01-31" version="1">MVSDLQIIYERDPAARNWLEVLFCYPGLQALSLHRTAHWLYSAGLPFVPRLISQISRFLTGIEIHPGAKIGRGVFIDHGMGVVIGETAIVGNYAVIYQGATLGGTGKETGKRHPTLGENVVVGAGAKVLGNIQIGNNVRIGAGSVVLREVPSDCTVVGIPGRIISRKRQTGDAQNSQNTPDLEAQAIRALFDRIKYLEDQVNILKSSSCSPKTTESEPTEAKRNELSLSSDRLIAEFLDGAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZE9</accession>
    <name>A0A2G4EZE9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54886">
        <property type="protein sequence ID" value="PHX54886"/>
        <property type="gene ID" value="CP500_013705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="71" mass="8237" checksum="862E63184DE82A31" modified="2018-01-31" version="1">MATQEDRIKQREALEDAHGNFVEPYINQLIEVNAQSLPNIDVALPGFCCVSGWLVLVIFYGFWMRYRMSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZF5</accession>
    <name>A0A2G4EZF5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutaredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">grxD</name>
        <name evidence="9" type="ORF">CP500_013745</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54894">
        <property type="protein sequence ID" value="PHX54894"/>
        <property type="gene ID" value="CP500_013745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014434">
        <property type="entry name" value="Monothiol_GRX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="PTHR10293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005894">
        <property type="entry name" value="Monothiol_GRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00365">
        <property type="entry name" value="TIGR00365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="8">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="12024" checksum="45A34089EBABD432" modified="2018-01-31" version="1">MSTAPHQRIDDLVKQNKIIVFMKGNKLMPQCGFSNNVVQILNRLGVPYETVDVLADQEIRQGVKEYSNWPTIPQVYINGKFLGGSDILIEMYQKGELQEAVEVALAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZP2</accession>
    <name>A0A2G4EZP2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_013230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54979">
        <property type="protein sequence ID" value="PHX54979"/>
        <property type="gene ID" value="CP500_013230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="3">
        <location>
            <begin position="23"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="245"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="33393" checksum="06E01C2E3C29939D" modified="2018-01-31" version="1">MLPFKYPVPQTDPPRSGRETLPTMYDLPSEDPEEPGLPDEFHDLQPQLLSLTFRPPNYRASQIFSGTDMNLYYDVRHPMWHKRPDWFGVVGVPRLYDEIDLRMSYVVWQEGVNPFVIVELLSPGTEKEDLGDNVNEEKLPDESGNGACNGQVIQSQMDGKPPRKWDVYEQVLRVPYYVVFSRYTNRLRVFELEAGHYLELELSDSRVWMSDLNLGLGLWEGEFLGIDRLWLRWYDIDGNWILTPEEQERLRAEVAESRAEEAEAQLESLIQRLRESGIDPDVFLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZS0</accession>
    <name>A0A2G4EZS0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55004">
        <property type="protein sequence ID" value="PHX55004"/>
        <property type="gene ID" value="CP500_013055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="776"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="824"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="920"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="919"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="977" mass="109988" checksum="865C26A6C13C7260" modified="2018-01-31" version="1">MPIDDEDFQIEISDDRKLQLFTDRHEFTRRFASYLNDDPPPAKILYFFGDGGNGKSLLLKHLQYHCCKKFAPQVWQQLRALPESQAAEVADFVRNAEPKTYTPIPVVKHDFGLIPIKEDKPQDRFYGLLMLRRNVAAATKKYKFKFPNYDFACFWYLLNKGESNATLSQLFPDDVAELVAPVVETFAEFPVVAQAVAVLKGIDKLGGIKRAMKLIQNRLGVSDETADEIRRKDIDTELIDCLPKLFAGDLNAAMASINKPDRLVMLFDTHEKMWDEKRNSQGATFWYQDEWFRRLLRALDYKLGIVVAVAGRDCPVTQLRWPNAPRFPIPEDYIDKQLVWHLSPADARDYLHKVEIDKADLADAVIKYASVNPDENWENLQVHPFYLGLCADVVLAERRRGIELLASDFARIPKLENKTAELTDRLLLYVDREVRSAVHSLSACRAFDEDLYVKLGGGCHFQASSANFEVLTSFSFVWKSEKRGDNWYRIHDLLRRLDADRDNPKTRRAHEVLEGHYREVGDGAEAIFHANRLDWLRGVKEWVEVFEEALELSRYGECELLLGVRDELWIKSDFRLGRISLSEGDYYARLARYVEAKQEYLEAVAAYERQLIITPNNKDTLNSKGIALGCLGNLQVKVSEFEAAKLSCSEAIAAFNSALLIASDDKSALSNKGNALTSLGELQAKLTEFEAAKQSYSEAIATFNSALVIAPDNKSALNNKGVALECLGDLQAGLSEFEDAKQSYSEAIDAYNSALQIAPGYISGIQNKGNALRCLGDLQAKLSEFEVAKQSYSEAIDAYNSALQIAPEYSYALNNKGMALKSMGKLKAELSEFEAAKQSYSEAIDAYNSALRIAPDDNYALNNKGIALKNLGDLQKELSEFEAAQHSYLEAIDVYNSALRIAPGDNYAIHNKGLALKSMGDLQAQLSEQEEALKNWQEALQMFNRSLAIAPNDDRLRNRRDSLQESLNNLGEDTVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZW0</accession>
    <name>A0A2G4EZW0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MOSC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55046">
        <property type="protein sequence ID" value="PHX55046"/>
        <property type="gene ID" value="CP500_012830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOSC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="76"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="30145" checksum="0AA8D43B05FF3C51" modified="2018-01-31" version="1">MAYVASIHIYPVKSLDGISVSQATILASGALKGDRSFAICDDQGEFVSSQRHNGTCFLRLSFNVSNNIVGLKIQGTEQENFFHIDRERARIESWLTSYFGFPIKLVENLITGFSDNIAALGPTIISTETIAEIASWFPRVCVNEMRQHLRANIEIGDVPPFWEDQLFAASDEVVRLQIGKVTFEATHPSQCIVSTRNSFREEVYPNFQEVFTAKRNKIMPHSARRSPLSHLSQLNINTRVLDRTSEKIIQIGDEVKIISIKSIADSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZX3</accession>
    <name>A0A2G4EZX3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55044">
        <property type="protein sequence ID" value="PHX55044"/>
        <property type="gene ID" value="CP500_012820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="276"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="310"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="344"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="395" mass="44528" checksum="7C9CD0B6032FB15E" modified="2018-01-31" version="1">MNLTLCMIVKNEEATLPRTLASVKDVVDEMVVLDTGSGDRTCEIAREFGAKIYHFEWCDDFAAARNECLKYAKGDWILVLDADEVLVPQIVPLIKQGIQGDRTLLINLIRQEIGASQSPYSLVSRLFRNRHDIRFSRPYHAMVDDSVAEILQREPESKIVALPDVAIWHSGYHPDAIANKHKFQKAQAAMERYITYYPSDAYACSKLGALYVENGQIQRGIDLLTKGLTSVTIDDSIVYELNYHLGIAYRQQQQFVKAKEHYQAAINTNIFPPIKLGAYNNLGNLFKDEGDLTSAEKAYKAALKIDPYFAIGHYNLGLTLKAAGNLADAIAYYRQAIKIDPEHAEAHQNLAVALLKIGKMPESLAEFKKAIVLHEQRRPFEAERLRRGLQEMGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZY6</accession>
    <name>A0A2G4EZY6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ATP-dependent chaperone ClpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_012730</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55082">
        <property type="protein sequence ID" value="PHX55082"/>
        <property type="gene ID" value="CP500_012730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="13">
        <location>
            <begin position="6"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="126"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="815"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="482"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX55082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="977" mass="108621" checksum="F5E4447C6CB08F47" modified="2018-01-31" version="1">MQPTDPSKFTDEAWESIVKSQDVARRFANQQLEVEHLAIAILEQLGLANTILSLAGIDVVRFAQQLEAFAKRQPRVTNADQLYLGRGLDVMLDVAEATRVTWQDNFIAVEHLLIGLVEDERVGRRLLTRGDGPPGRPGYDRKPAAGTIDRPKLEEAIKSARATAKVTEKNSETSKPSRSNPKAPDQDGEASSDALSKYGRDLTEAAKAGKLDPVIGRDEEIRRVVQVLSRRQKNNPVLIGDPGVGKTAIAEGLAQRIVNGDVPESLKNRQLFSLDMGSLIAGAKFRGEFEERLRSVLREVIDSDGQIVLFIDELHTVVGTGGGGSSGSGMDAGNLLKPMLARGELRCIGATTLDEFRKHIEKDPALERRFQQVFVGEPSVEDTISILRGLKDRYERHHGVKITDSALVAAATLSFRYISDRFLPDKAIDLVDEAAAHLKMEITSKPVELEVIDRRVMQLEMEKLSIEGEGKGAISTAISPRIERITSEIDILKVKQEKLSSQWSGEKQLLDAINKLKAEEDQLRVQIEQAERAYDLNKAAQLKYGKLETAVRDREAKESELLKQQSQGSSLLREKVTEGDIAEIVAKWTGIPVNRLLESERQKLLQLEKHLHHRVIGQQEAVTAVAAAIRRARAGMKDPGRPIGSFLFMGPTGVGKTELARALAEFLFDSDDAIVRIDMSEYMEKQNVSRLVGAPPGYVGYDEGGQLSEAVRRRPYSVVLFDEVEKAHPDVFNILLQVLDDGRITDSQGRLIDFRNTVIVMTSNIGSDHILDVFAKKEKTAKKPATRKQEVPDLSSQKTNYKVDDDGTVEISASRVSDAVSSPSVQEPESLPIAERETDEEYEQMLKRVMTALRSHFRPEFLNRVDETILFHTLSKTELRQIVSIQVKRIERLLAEQKITLELSDAAKNHITDVGYDPVYGARPLKRAIQRELENPLANKILENAFVEGDTIAIDCENNALQFRKIESRPALVGNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F013</accession>
    <name>A0A2G4F013_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">8-amino-7-ketopelargonate synthase</fullName>
            <ecNumber evidence="8">2.3.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">bioF</name>
        <name evidence="10" type="ORF">CP500_012525</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42288"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9955"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78846"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="EC" id="2.3.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.47" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55093">
        <property type="protein sequence ID" value="PHX55093"/>
        <property type="gene ID" value="CP500_012525"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008710">
        <property type="term" value="F:8-amino-7-oxononanoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004723">
        <property type="entry name" value="AONS_Archaea/Proteobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00858">
        <property type="entry name" value="bioF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="9">
        <location>
            <begin position="43"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604723-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="389" mass="42173" checksum="7C099F79CD7C25FE" modified="2018-01-31" version="1">MTPNPYAWIDKSLDTIRRADWYRSPQLIESCPGPRVKLAGDWLINFATNDYLGLAGDDRLIQAAIAATQEFGTGTTGSRLVGGHRDLHRQLEQAIANLKQTEDALVFSSGYLANLGAIASIVGQRDLILSDKYNHSSLKNGAILSGSQTVEYDHCNVEDLRTQLEQNRASYRKCLIVTDSVFSMDGDLCPLPKLLDLARQFNCMLLVDEAHATGVFGASGAGCVEHFGCTGETLIQVGTLSKALGSLGGYVAGSAALIDFLRNRAPTWIYTTGLTPADTAAALEAVKIVQQEPDRRDRLQQNIETLKYAAFNNCQLPISNSISPIFSFPLKDAATALAASTKLKEMGIFAPAIRPPTVSVSRIRISLMANHEPAHLQQLVETLGRIAPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F057</accession>
    <name>A0A2G4F057_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF86 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_012205</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the HepT RNase toxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55140">
        <property type="protein sequence ID" value="PHX55140"/>
        <property type="gene ID" value="CP500_012205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008201">
        <property type="entry name" value="HepT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037038">
        <property type="entry name" value="HepT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01934">
        <property type="entry name" value="DUF86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="12762" checksum="FDEBDE65BE4B9966" modified="2018-01-31" version="1">MFIDNNTRLHHMLDAAKEAVLFSANTNRKDLDTNRMLTLSLVKCIEIVGEAASRISTDRQKELPQIPWSQVIGMRNRLIHAYFEVNLDIVWDVITDDLPSLIVELEKIIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F085</accession>
    <name>A0A2G4F085_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55158">
        <property type="protein sequence ID" value="PHX55158"/>
        <property type="gene ID" value="CP500_012305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="384"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="424" mass="47774" checksum="08E194BBB8164509" modified="2018-01-31" version="1">MNSTTNHHNSTSSIVAWQYLPQELTALLLEQIKSQMSQREKRYAEGEKAKNRINDLTPLAKNTPNPETKKIVNILVGLISAITFSAGAKILTSGMGSMSIPASLFIGGAAGVVADKKVMKVMEHHRKKSSTQQALQDIQKQKQAHPPKNEFGELYYESQTALVLQVEGQYLNKLPFSDVGLALGLSGTEYAMSLGIVIGLGLPGGIVLNAIAASLPVVMLWGAASLQNDAFEMPGHARALIGQYESSLPQEITEIEANQIAGIDEEVTLKQRELAYEQALNLRREKFVSEGDTSGRLKNWDMVEADFQIGWYEKEKHQIEKEQDEKREQRYFKFKADVAQIAEQHQPPAGTYSPEQMAQLKNEWVEVQEQKLKEILAHDIQWLNHKYGNKIKHYEEEITTARQRYAEAESRWRQERDLQKTSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F091</accession>
    <name>A0A2G4F091_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Carbonate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_012345</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55166">
        <property type="protein sequence ID" value="PHX55166"/>
        <property type="gene ID" value="CP500_012345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="791"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="829"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="860"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="894"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="15"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="921" mass="98983" checksum="DE0967FCE3578DA7" modified="2018-01-31" version="1">MPATAANDVDVAEQSWHYLERSKVATTLETNLENGLDPAEVANRQQQFGSNELTVKAGKPAWLKFILQFNQPLLIILLSAGLIKALIGEWLNASVIWGVTTTNAIISFVQEAGAEKKIDALAKAVTTEATVIRGGKKLRVPSKELVVGDLVTLTSGDKVPADLRLIKVRDLQIDESGLTGESVAVEKELGQSGDLVLPQETPLAERDNMAYAGSFVTFGQGSGIVIAIANKTETGKISQLLDRHIDLTTPLTRKFNEFSQNWLLFVLGMATLTFAVRLGRPVPAGVSAFKEAVEPAVALIVGAIPEGLPAVITVTLAVGVSRMATRHAIVRKLPAVETLGGATVVCSDKTGTLTENQMTVQEIYSGGESYSVTGTGYSPEGEIQLNQLPINVSQSPTLQECLQAGLICNDSHLEFKDNNWIAIGDPTEGALIAAAKKAELSQQVLEKSMPRLDSIPFESQFQYMATLHQTPTGKVLYVKGSVESVLSRCGSSLDTQGNPAEVDREQAHHQVDEMAKQGLRVLAIAKKVVPESQNSVNHSDLESGLIFLGLQGMIDPPRAEAIAAVQACQTAGIQVKMITGDHIATAKAIARRMGFRKTKHNRELVAYTGAQLAAMDKNELAEAVEAGSVFARVAPEQKLRLVEALQLQGEIVAMTGDGVNDAPALKQADIGIAMGSGTEVSKEAADMILTDDNFASIECAIEEGRSVYKNLLKAISFILPVNGGESMTILLSTLLGRELPILSLQILWLNMLNSITMTVPLAFEPKSPGVMQQQPRSANEPLLTASRIKRIIAISLYNWTVIFGMFEWVRQADWGTIELARTMAIQALVMGRIFYLLSLSQLLPSLIAKFSGSKEEVSGAPALGVGIVLAVILQIIFANSPFINGIFETAPMNLDQWLICFGVALPMIGVALSVNRFDPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0A6</accession>
    <name>A0A2G4F0A6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55195">
        <property type="protein sequence ID" value="PHX55195"/>
        <property type="gene ID" value="CP500_012100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="287" mass="31447" checksum="9CEDD6934D982AE5" modified="2018-01-31" version="1">MKNKRLGNTNFNISTIGLGGMPLSLSGRPTEAQSIAVIHRALDLGVTLIDTADSYCQDQSDKHHNEELIAKALQQYTGDIRAVTVATKGGLMRPQGAWTRNGNPHHLRKTIRESFEALGGQKPIDLWQYHSPDPSYTIEAALAPAKEAVEAGMIRFVGVSNFSVEQIKRARDTVEIASVQNQYNPWHREPESDGVLEYCEAEKLTFFPWSPLGGSRRVTSLQDIPAIAKLATEKNVSVYCIVLAWLLAKSPCIVPIPGATKISSIEDSVQAIDVQLTDVEVQQISAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0G7</accession>
    <name>A0A2G4F0G7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Photosystem I assembly protein Ycf4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ycf4</name>
        <name evidence="10" type="ORF">CP500_013415</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Seems to be required for the assembly of the photosystem I complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the Ycf4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54947">
        <property type="protein sequence ID" value="PHX54947"/>
        <property type="gene ID" value="CP500_013415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00437">
        <property type="entry name" value="Ycf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003359">
        <property type="entry name" value="PSI_Ycf4_assembly"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02392">
        <property type="entry name" value="Ycf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="188" mass="21153" checksum="A30C1EEBF25FA83D" modified="2018-01-31" version="1">MTAQTTSSIDRILRQEVLGSRRFSNYWWATIVSIGGTGFLLSGISSYLHVNLLPFADPTMLVFIPQGIAMGFYGVCALLLGSYLWLTVLWDLGGGYNEFDRETGSIRIFRWGFPGKNRKVDFTCKTSDVQSVRVDIKDGLNPRRSIYLKLKDRRQFPLTRVGQPISLAVVENQAAELARFLKVPLEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0I9</accession>
    <name>A0A2G4F0I9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GUN4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55284">
        <property type="protein sequence ID" value="PHX55284"/>
        <property type="gene ID" value="CP500_011600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16383">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008629">
        <property type="entry name" value="GUN4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037215">
        <property type="entry name" value="GUN4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34800">
        <property type="entry name" value="PTHR34800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05419">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140869">
        <property type="entry name" value="SSF140869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="GUN4" evidence="2">
        <location>
            <begin position="73"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="222" mass="25800" checksum="301643E3F2D1420F" modified="2018-01-31" version="1">MTVTGLIIFLIIILLVFSVVILKKNHRLHQQRKQKNIRENLSEQLSEEKEEITTIPPPPILNIPKPTSIFLVSDKGIDYTELQHLLENLQWQKADAETRFILQKIGNVVNSNYLNANDIFQLSCIDLQTIDTLWLYYSNCHFGLTVQYQLWQESKQELNLFGEWVGWCKRGVFIRESELIYDLTAPAGHLPVAYIPIVGNCLWIVLDSVTWFNQKLQSCQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0N7</accession>
    <name>A0A2G4F0N7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptide ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55315">
        <property type="protein sequence ID" value="PHX55315"/>
        <property type="gene ID" value="CP500_011465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="1">
        <location>
            <begin position="94"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="550" mass="60673" checksum="C248357290797B4B" modified="2018-01-31" version="1">MGTDRLLAKISIRPWVLKVLALFSLCCFLTASCGLRTNQSVNSASDNAQNDRITIGTTLKLRTIDPADAYEVISGQLLHNLGDTLYTYESGTTKLIPDLATAMPKISPDGLTYVIPLRQGVVFHDDTLFNAAAMEFSLQRFIKNGGRPAFLLGDAVESVKATGEYELTFKLKKPFAAFSALLTFAGTCAISPKAYEIGEGKFKPDTFVGTGRYKLAKYGTNSLKFEVFDKYWGEKPANQGIDLLLLSSSANLFNTFRTGAVDVAYLSLDADQVRSLDEGAKKGKWQEFAAESSTVSYMTLNIKSKPLDNIDVRQAIAAMIDRPLINDRVLRGQAQPLYSLIPTTFDVHKPVFKELYGDANMTKAKELLTKAGYSAANPLVLQIWHPSGSTKRALVASTIKALAKLKMDGIMQVEVNSVEAPTLFQNVEKGIYPTVLVDWYADFFDADNYIQPFLDCATGSAAGGCEKGASQGQGSFYYSDRANQLIAQQRKEPNPEIRKAIFAELQDILGRDVPFIPLWQDKDYTFAQKNVTGVSLEPTQAFPFWFLKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0P5</accession>
    <name>A0A2G4F0P5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_011345</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.-" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55332">
        <property type="protein sequence ID" value="PHX55332"/>
        <property type="gene ID" value="CP500_011345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="PTHR10543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="499" mass="55402" checksum="D547AC14FF122406" modified="2018-01-31" version="1">MQNLETSQSQTAAKTLSYDRTDWQRGYESQPNESDYWIDDIEGEIPADLEGTFFRNGPGLLDINGEPIHHPFDGDGMVCAIAISDGRAHFRNRFVHTEGYLAEQKAGKILHRGVFGTQKPGGWLSNIFDLKIKNIANTNIIYWGGKLLALWEAAEPYRLDPCTLETIGLDSLDGLLKPGEPFAAHPRIEKGQNGAGDTLVNFSVKPGLSSTITIYEFDESGKLLHSHAHTIPGFAFLHDMVITPNYCIFFQNPVSFNPLPFVLGMRSAAQCIQFSPKKPTQAILIPRNGTDEVKVLETEPCFVFHHCNAWEEAGEVFVDSVCYESFPNVGPDGDFLEIDFDSLPAGELWRFKLNLSDNTVEHKVIESRCCEFPTLHPNYAGQPYRYLYIGAANSPTGNAPLQAILKVDFLTKEQQIWSVAPRGFAGEPVFVPRAVSPDTATAEDDGWLLMLMYDAAKHRSSLVILDARDITKGPVALLHLKHHIPYGLHGSFTSSVLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Q8</accession>
    <name>A0A2G4F0Q8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_011395</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55342">
        <property type="protein sequence ID" value="PHX55342"/>
        <property type="gene ID" value="CP500_011395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="154"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="230" mass="24857" checksum="7B5BE2423BC0ACF4" modified="2018-01-31" version="1">MKPAYPLRILLVEDDELFRLGLQTRLQQESCLQVIAEAEDGETAVELTQEHLPDVVVLDVGLPGIGGIEACRQIKQRHPGIPVLILTSHSQKSLIERLIAAGAQGYCLKGIAAENLVLAIRSVAAGASWWDRAATAEIRAVFANPEPVKLGLKSDILENPLTPREQEILALVAGGKSNQEIAQILYIAPGTVRVHVHAILQKLEVRDRTQAAVLAIQKGLVAEELLGSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0W9</accession>
    <name>A0A2G4F0W9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_010970</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 7">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55388">
        <property type="protein sequence ID" value="PHX55388"/>
        <property type="gene ID" value="CP500_010970"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011278">
        <property type="entry name" value="2-MeCitrate/Citrate_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01800">
        <property type="entry name" value="cit_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="379" mass="42795" checksum="AC25D3CC37BE7E77" modified="2018-01-31" version="1">MVVGEFKPGLEGVPATLSSISFVDGQKGLLEYRGISIEELALKSSFVETSYLLIWGVLPTKEELEAFEHEIRYHRRIKYRIRDMMKCFPERGHPMDALQASAAALGLFYSRRALANPAYIREAVVRLLAKIPTMVAAFQQMRRGNDPVRPRDDLNYSANFLYMLNEREPDPLLANIFDICLTLHAEHTINASTFSAMVTASTLTDPYGVIASAVGTLAGPLHGGANEEVIEMLERIGSVENVRPFVEKCVENKDKIMGFGHRVYKVKDPRATILQGLAEKLFENFGHDDYYDIAVKLEEVVEEKLGHKGIYANVDFYSGLVYRKMGIPIDLFTPVFAIARVSGWLAHWKEQLEANRIYRPTQIYTGTHGESYIPIEQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F140</accession>
    <name>A0A2G4F140_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55465">
        <property type="protein sequence ID" value="PHX55465"/>
        <property type="gene ID" value="CP500_010580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="295" mass="32049" checksum="043588A750D274D7" modified="2018-01-31" version="1">MSKTVFELVDQLPKDNMTVKALRALDFVLPGQWDNLVGFENTIRSVTGETDEELIQQIGDRAIYLYNDTSQGYQRALWLYQTIDSTDKALGAAALANKIAKNVPLLSMLGNLTPKPEKAQTIDLSLKLVTELLAFCQINGLPGDSIGDFAGALGDYGGESLMRMAALVCFDGLIPLGPDFIMATQGWIGRLSPSDLQENPSFNAISSMIPGNHPAGQLGFIGESFSSVTGWMSSFVSDRGLTPQNVMNQLQSFVEISADKADYVGALLDVSTNYYEHTGVQTLARRLIERAVAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1G2</accession>
    <name>A0A2G4F1G2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Photosystem II reaction center protein J</fullName>
            <shortName evidence="7">PSII-J</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">psbJ</name>
        <name evidence="8" type="ORF">CP500_010000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cellular thylakoid membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PsbJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55600">
        <property type="protein sequence ID" value="PHX55600"/>
        <property type="gene ID" value="CP500_010000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01305">
        <property type="entry name" value="PSII_PsbJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002682">
        <property type="entry name" value="PSII_PsbJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037267">
        <property type="entry name" value="PSII_PsbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01788">
        <property type="entry name" value="PsbJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161021">
        <property type="entry name" value="SSF161021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="1 7" id="KW-0674">Reaction center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="39" mass="3906" checksum="19F53976DBDA6D76" modified="2018-01-31" version="1">MSSGGRIPLWLVATVAGLGALGILSLFFYGAYAGLGSSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1H3</accession>
    <name>A0A2G4F1H3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-demethylubiquinone-9 3-O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ubiG</name>
        <name evidence="2" type="ORF">CP500_009925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55588">
        <property type="protein sequence ID" value="PHX55588"/>
        <property type="gene ID" value="CP500_009925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008425">
        <property type="term" value="F:2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010233">
        <property type="entry name" value="UbiG_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01983">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="54"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="281" mass="32013" checksum="00B33F966B5213B4" modified="2018-01-31" version="1">MVKTEVKNDLEFYDENADNWWDEKSKIYALYHLNKPRFEFFDRHATNWQGLKTLDVGCGGGFSCEFMAERGAIVSGIDQSQKCVQAAKNHAVISGFEIDYRQGFAENMPYDDNTFDVVICVDVLEHVADYKQVVSEVHRILKPGGLFFFDTINRTFSSQVVMIGLMENILQEIRKGVHDWDKFITPEELSVVMGNTGFGNIEIKGFDMFGEIGALLSQMQDFWENLMGGKQLFPDADVMKQAYQTLMSNLGNYVDYKKSGLFKIQINEDTSIMYVGVGVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1N5</accession>
    <name>A0A2G4F1N5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55662">
        <property type="protein sequence ID" value="PHX55662"/>
        <property type="gene ID" value="CP500_009640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7452" checksum="96FAB14CE4AF02C3" modified="2018-01-31" version="1">MKNFNFPIRNTDNCQENPLAFVSGKIVHIVHPNGEVEATTVEQIDRGQTKIPLDKCLVWRRIGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1P3</accession>
    <name>A0A2G4F1P3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1868 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55683">
        <property type="protein sequence ID" value="PHX55683"/>
        <property type="gene ID" value="CP500_009735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="28216" checksum="657D1839BBD9E8ED" modified="2018-01-31" version="1">MTLLDSYKSQVEHIQESPKFKPDEAGVKVAVPFPGYSVITPPAGEDTENAVLYANLHSCQQRLLQELHPGSLIALSPDSFHVTVADLIWSSAFQDASDKNPEFELQLREQMTDRFATSKPVQAGRPPIRWIVLGFMVMTRAIGVCVAPTDENSYKQILELRRSIYQNPDLIGLGIEQQYHFTAHITLGYFGDTGPNLDRSRLCSLLSELNEQWLDTPQELSIHRAELRKFDDMNRYYREPDWPVFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1T2</accession>
    <name>A0A2G4F1T2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-ketoacyl-ACP reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55695">
        <property type="protein sequence ID" value="PHX55695"/>
        <property type="gene ID" value="CP500_009365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="274" mass="29930" checksum="56F4E5DF5D4EE2E9" modified="2018-01-31" version="1">MQLQGKTALVTGASRGIGRSIALELAKQGIKRLLIVARNRQQLVELATEIEVLGVEVVPLALDLTQSVAVNIAIAQAWRDHGPIHLLVNCAGVAHQASFLRSPLPLIQEEIALNLLGTYTITRLIARRMAAQKDGTIVNVSSLMGKIAAPTMATYSATKFAILGFTQALRSELAAYNVRVTALLPSLTDTDMVRDLEQFRWVVPTTPEKVALALVAGLHKDAPEILVGYQSHLAVWCHRIAPWLLDCVLRMATPELRDKSRRDRNLRSALASGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1V4</accession>
    <name>A0A2G4F1V4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55457">
        <property type="protein sequence ID" value="PHX55457"/>
        <property type="gene ID" value="CP500_010785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="153"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="31907" checksum="EDA5E9DCF18ED799" modified="2018-01-31" version="1">MTWLILGIFTAFFEALKDVFGKQNLKKSDEYVVAWSLSFFSVIFLIPWVIHTGIPTLNSQFWVALLIGGSINAVTALLYIKAIKVSDLSLTVPLVALTPLFMLLTSPLIVGEYPSFFDYIGILLIVTGSYLLNIKEKSQGYLAPFKALLNERGPKLMLIVAFLWSITSNFDKIGVQNSSPIFWLFSIVGTMSILLLPVLLYKTPNPSRKILKELPMLAAMGFFNAIGVLCQMQALTLTLVVQVIAIKRTSVLMGVLFGHFIFKEKDIQQRLLGAVIMVWGVFFISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1X2</accession>
    <name>A0A2G4F1X2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="6">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">tilS</name>
        <name evidence="8" type="ORF">CP500_009045</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55773">
        <property type="protein sequence ID" value="PHX55773"/>
        <property type="gene ID" value="CP500_009045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="7">
        <location>
            <begin position="29"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="34"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="369" mass="41841" checksum="43F9101674772796" modified="2018-01-31" version="1">MPNSQWTQLHAQLHRTLLQRKILPPNQRLLVAVSGGQDSLCLLKLLLDLQPKWGWELAIAHCDHRWRSDSEANANHVASLAKNWGICYYQKTADRIPNTEAAARNWRYQSLTEIAIANNYPYIVTGHTASDRAETLLYNLIRGSGADGLSALSWVRPLADFRLPILDIGLGNPHKNPKSKIQNLKSKISLVRPLLEITRSQTGQFCQEQKLPIWEDSTNQDLQYARNRIRSELLPYLETHFNPKTQQALAQTAELLRADVEYLELAATDLLQQAMSEINEGEHENFQLPVKLNRQILQAAPLSLQRRAMRQLLQHILPNAPSFESVEKLTALIVAPNRSQTDPFPSGAIATVEKPWITIKYIAELPSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F229</accession>
    <name>A0A2G4F229_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55824">
        <property type="protein sequence ID" value="PHX55824"/>
        <property type="gene ID" value="CP500_008695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8187" checksum="9672CB846E8D12D9" modified="2018-01-31" version="1">MGYVRLRIRELAEQRGWTFKEVADRSGVNYNTVRSYVQRDTLNTVDLSAVYKIARAFDVTMEDLVEILED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2A1</accession>
    <name>A0A2G4F2A1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phycobilisome protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_008510</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cellular thylakoid membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55876">
        <property type="protein sequence ID" value="PHX55876"/>
        <property type="gene ID" value="CP500_008510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000081">
        <property type="entry name" value="Phycocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3 4" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="2 4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="22033" checksum="3D540E12B82BD1F9" modified="2018-01-31" version="1">MTMQLSERAKKLIPKARIVSFATWKNLYSDEVIAIFQEADNRSEYLTDEDLESIQNLVPDTSLMLAQVRLLREQAPNLVANARAKVLTDFPNIAEPGNDLYPPARAEACWRDFWHFLRSVTYGIAGNNPEFLSQEGLENMDLLYQELRVPVPAMLCGLEQLKTVSLQQFSSEEQDLLGLNFDHLIGALKQFSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2B3</accession>
    <name>A0A2G4F2B3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1311 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55901">
        <property type="protein sequence ID" value="PHX55901"/>
        <property type="gene ID" value="CP500_008375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009739">
        <property type="entry name" value="LprI_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07007">
        <property type="entry name" value="LprI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LprI" evidence="1">
        <location>
            <begin position="41"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15958" checksum="7677DEA16493CBA3" modified="2018-01-31" version="1">MKIELRKGRSHFWSIALLAVVGTISVLGQSGRSVMAQQLNCDRPQGDVEVRACIRLRYELADKRLNDVYKQLIAKLSKEEKALLAEAQLGWIKQRDNTCEFEVYRNLGGTGYQGFLNECLERMTKQRTAELEKYFKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2G0</accession>
    <name>A0A2G4F2G0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55963">
        <property type="protein sequence ID" value="PHX55963"/>
        <property type="gene ID" value="CP500_007910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="106"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="290" mass="33121" checksum="38E57D92E89FFEAC" modified="2018-01-31" version="1">MAHLNRRRPENISGNFYVDSTCISCDTCRWMAPEVFVQVGEQSAVYQQPTNDTAERRSLAALLSCPTSSIGTVDKPKNIKEVQQSLPAIVTENIYHCGYHSEKSYGAASYLIVRPEGNILVDSPRFVPPLVKNMEAMGGIRYLYLTHRDDVADHQQYRDYFGCDRILHTDEINADTRSVEIQLSGNEPHQIADDLLIIAVPGHTQGHTVLLYNNKFLFSGDHLAWSDNLQQLIAFRQVCWYSWEAQIKSMQNLANYEFEWVLPGHGRRYNADRETMSNQMQKCVAWMLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2J5</accession>
    <name>A0A2G4F2J5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55969">
        <property type="protein sequence ID" value="PHX55969"/>
        <property type="gene ID" value="CP500_007940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="7200" checksum="003A3E4DB721E010" modified="2018-01-31" version="1">MQRCKTDGGDSVKKNTKLDRLQFIWLRGGDFQKNNCSITAVYSLTHLGGDSIEIIKHLQTGFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2P1</accession>
    <name>A0A2G4F2P1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WGR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56043">
        <property type="protein sequence ID" value="PHX56043"/>
        <property type="gene ID" value="CP500_007620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008893">
        <property type="entry name" value="WGR_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05406">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00773">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="SSF142921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WGR" evidence="1">
        <location>
            <begin position="5"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1060" mass="120135" checksum="5FAB651EB405B2D6" modified="2018-01-31" version="1">MKLIKRTALYFQDDRSDKVYEVDLCQVGENLYLVNFRYGRRGANLKEGTKTDTAVPLAQAEKVFDKLVAEKVKKGYREVATEAPNVADVAPAATREEAILNNIAAGGSPKWPLERAIWRAGELKIAEAGPLLIKLIGTGEPLRDYCIAWSLGWCGGEGAVAALTRLYRDAATAEFVARIAFEGLLKLADREVRSQMRSSIIELLPVELRELARNGSAEEFSATLKTYLDTKDGSRFAVLDTIYQIDSECVRSTLLDILSTAPFKPNYFKPIRHIFKMAEYRHDAEVFAIIADRLEREQAMYQSNSYGVYIPGGGYLRKIQWQHNKKTNNYEQFQLSEFQNEMQSPNPRIAYSNNTRAYFIKRVWRTLKQLGEEGDADYVKMAVSILLRYVDSDAEEVLQRTYYQWNRSNWTRFESGTADWDIFAGYLTFNHILYENSPRYVYLTNSKAWRCQEGYKPGDPEPEVREEAFPELWEQNPDRLLQLLLESNCRPVHHFAVKALKACPLFLTEIDVSTIVKIIDRPYEITAELGCNLVIQNQYNRYPDHREVILAVVNCVFQGGRESAYGWLEEQRDRILEDSELIGALVTSLYGDARQFARRILSSSIISERTAKVLIGRIIAHLLAFEITSISTTNTPILAGEIAETLLVCFPAQLRNLGLGVVLDLLRHAIAENQELGARILLNHEITAADLPPELIESLIESPYEQIRGIGISLFGQLSDATLTGDKRVLILGMAVNALADIRNAIQPVIHRLAAGNPEFSAQLAAEFIDILMLPERHEGVHSYLINLLREDLPGWMPSMNRDIAWRLLKTKSSAAQELGGFLLSTNSADWAADFDTIEIVKLASHEILSVREAARQMFLQKLDAIRTNSQEMLSAVRMLEAKWQDSREFAARIFRTELTAEDWTPDVMVSLCDSIREDVRQFGRDLVIRYFRDECGHDYLLKFSEHPSADMQLFATNYLESYAANNPERIRELMPFFVAVLSRVNKGRVAKQRVLAFLDGEAQKSEAVAKVVAEILTRQSATIAIADKAAAIQTMLKIRKSYPQLELPIQVKPVLEVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Q4</accession>
    <name>A0A2G4F2Q4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_009260</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55737">
        <property type="protein sequence ID" value="PHX55737"/>
        <property type="gene ID" value="CP500_009260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:cellular aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="PTHR43570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="8"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 6">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="455" mass="50280" checksum="9E681AB360D1B7C0" modified="2018-01-31" version="1">MVISVSDIIQQQRQFFATGKTKDVDFRIEQLQLLKSAIELNQSQIVAAVKADLNRPEFEAYFEIASIAEVKYAIKNLKSWVKPKKVPTSIDQFPASARIFPEPLGVVLIIGPWNYPFQLMISPLVGAIAAGNCALLKPSEIASHTSTVVADMISKTFDPAYVAAVEGGVEISQQLLAEKFDHIFFTGGTKIGRIVMEAAAKHLTPVTLELGGKSPCIVDSDIQIEYTAKRIAWGKFINAGQTCIAPDYLLVDKKVKPQLMQAIKSSIQELYGDDPQTSPDYCRIINQRQLERLSAFIKDGEIAIGGQVQPEDRYISPTVLDNVSWDSPVMQDEIFGPILPVLEYDDLGDAIAQINARPKPLALYLFSKDKQKQERVLRETSSGGVCINDTVMQVGVTTLPFGGVGESGIGSYHGKASFDTFSHYKSVLQKSFWLELQWRYAPYKGKLDLIKKAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2S0</accession>
    <name>A0A2G4F2S0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phycocyanin subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cpcA</name>
        <name evidence="5" type="ORF">CP500_007460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cellular thylakoid membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56061">
        <property type="protein sequence ID" value="PHX56061"/>
        <property type="gene ID" value="CP500_007460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006246">
        <property type="entry name" value="Phycocyanin_a"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000081">
        <property type="entry name" value="Phycocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01338">
        <property type="entry name" value="phycocy_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3 4" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="2 4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="17578" checksum="79DDF7F036A7E63A" modified="2018-01-31" version="1">MKTPLTEAVTAADSQGRFLSSTEIQTAFGRFRQATASLEAAKSLTGNSQRLIDGAAQAVYNKFPYTQQMQGPNYASTATGKAKCSRDIGYYLRMVTYCLVAGGTGPMDEYLIAGIDEINRTFELSPSWYVEALKYIKSNHGLSGDPAVEANSYLDYAINALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Y1</accession>
    <name>A0A2G4F2Y1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56110">
        <property type="protein sequence ID" value="PHX56110"/>
        <property type="gene ID" value="CP500_007330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="233" mass="25613" checksum="6A129F6D79EF4068" modified="2018-01-31" version="1">MTKIQERPAFSVFGAKPSNALLVPEIPIAVRNNCQSGQWTIGDTDYGSKCSMTILKFSKFFGSLGQTSHTLWGQLWFIAETGELPQGVVMVTYIKNRSLNDFNRLVASVQSRGIEPATGIFIPEFTKHSGQKPDDSGVVKPINYYSLKWSWIERKDWAIIDQAAAVLSDMSNQSRMIDLEGTRQMICLDNLPPQEVACLMAAHASGESDAITLNSNGAMSLPSAEDKSTADLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Z6</accession>
    <name>A0A2G4F2Z6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55837">
        <property type="protein sequence ID" value="PHX55837"/>
        <property type="gene ID" value="CP500_008785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="28"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="282" mass="31475" checksum="BCF469F7937C33BE" modified="2018-01-31" version="1">MAFISIRGVEHYYEWITADGSAQPSGKPVMVFLHGWAGSARYWESTAQAIAQDFDCLLYDMRGFGRSPLPQQPPESSYELETYAEDLAELLAALNLSRVYINAHSTGASIATLFLNLYPEKVERAILTCSGIFEYDEKAFTTFHKFGGYVVKFRPSWLAAIPFADRIFMARFLHRSLPTEVSLAFLKDFLMADEEAAIGTMVTAVSKRAAEEMPEEFARLSVPTLLVAGEFDQIIPAIMGKQAASLSDKVEFVIIPNTSHFPMLEDAATYLQRIRDFLPAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F321</accession>
    <name>A0A2G4F321_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56174">
        <property type="protein sequence ID" value="PHX56174"/>
        <property type="gene ID" value="CP500_006950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="14275" checksum="8C6302AFE754857A" modified="2018-01-31" version="1">MTLSKKFWIIACFVYLVIILSIMLVADMGLLANFSLARPPFDKLGHFVLYGIASFLCHRAISKRMINILNYPIPFGPAIFTIFTAAEEMLQAILPNRTASIEDFLFSFGGIVVFYWIGEICDRKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F330</accession>
    <name>A0A2G4F330_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribose-5-phosphate isomerase A</fullName>
            <ecNumber evidence="2">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Phosphoriboisomerase A</fullName>
            <shortName evidence="2">PRI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpiA</name>
        <name evidence="3" type="ORF">CP500_006860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56159">
        <property type="protein sequence ID" value="PHX56159"/>
        <property type="gene ID" value="CP500_006860"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="PTHR11934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="33"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="90"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="103"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="240" mass="25796" checksum="599F47AF74BC080B" modified="2018-01-31" version="1">MTTEQDPVKLMKQQVGFAAADRVQSGMIVGLGTGSTTAYTIQALGDRLKSGQLQDIKGVPTSFQSEVLAKQYGVPLTTLDEIDRIDVAIDGADEVDPHLNLIKGGGAAHTREKVVDYLAAQFIVVVDSSKMVDKLGSTFRVPIEVIPMAIAPVTRAIEKLGGKPELRMGIRKAGPVITDQGNMVIDVQFDNLDNPGELEKTLNNIPGVLENGLFVNCTDLVLVGEIQDGKPVVREIFKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F342</accession>
    <name>A0A2G4F342_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56181">
        <property type="protein sequence ID" value="PHX56181"/>
        <property type="gene ID" value="CP500_006640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="12706" checksum="388C02C71F0F033F" modified="2018-01-31" version="1">MSISQFTLNLVEGSVSFSFSPQAARDLQSAIATLMESLKAVAAKTAGGKASPQKPMEYRYAGEVFFEVFCNPNIWPTPFAAKVLITVRDDRLRVTTEAELSRLRDDLAQYLEQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3A9</accession>
    <name>A0A2G4F3A9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protochlorophyllide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56263">
        <property type="protein sequence ID" value="PHX56263"/>
        <property type="gene ID" value="CP500_006245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013580">
        <property type="entry name" value="LI-POR_suB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042298">
        <property type="entry name" value="P-CP_red_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08369">
        <property type="entry name" value="PCP_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCP_red" evidence="1">
        <location>
            <begin position="12"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="7045" checksum="5B55DA83B0C267B0" modified="2018-01-31" version="1">MPDSEFSDDLKWTPEAKAKLKNIPYFVRGQARVRIEHLAREADTEVVTVDLVEQARIEFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3N1</accession>
    <name>A0A2G4F3N1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56087">
        <property type="protein sequence ID" value="PHX56087"/>
        <property type="gene ID" value="CP500_007210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="12"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="21826" checksum="9BBC3018E3C5D04C" modified="2018-01-31" version="1">MNAVTAKRFSIAEYHRLGELGFFAPDERVELIRGEIIKMAAKGRLHSVCNSTLFGELYTLLAKRAIVRGQEPIILSADSEPEPDVAIALNRSDNYLSSHPEPADILLVIEVSDSTLKYDRNTKLSLYAEAGIANYWIFNLVDIQLEMHSEPYHKIPGDFGYQLQRIVLPNGIVAIPGFPDLSLDLSLVFPVQTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3P6</accession>
    <name>A0A2G4F3P6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA sulfur modification protein DndB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dndB</name>
        <name evidence="1" type="ORF">CP500_005795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245727">
        <property type="entry name" value="M.Tbo703DndBP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56355">
        <property type="protein sequence ID" value="PHX56355"/>
        <property type="gene ID" value="CP500_005795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16412">
        <property type="entry name" value="dndB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017601">
        <property type="entry name" value="DGQHR-contain_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017642">
        <property type="entry name" value="DNA_S_mod_DndB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14072">
        <property type="entry name" value="DndB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03187">
        <property type="entry name" value="DGQHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03233">
        <property type="entry name" value="DNA_S_dndB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="379" mass="42462" checksum="298A82CF77A90B31" modified="2018-01-31" version="1">MSTPSFEYILPVIRGIQAGREYYVSMCPVRFLPKLFPFESEDLPPEMRAIRTLNQTRIPEIADYFVKNPTSYTCGAIAASIDADITFEAVGNEAEERKIGRLRVPMDAKFTINDGQHRRVAFEMALRENPQLGYETVALILFLDIGLEKSQQKFADLNSFQVPLEASLSVLYNHRDDGARLVKAVVKQVEVFRCLTEMERGSLNGRSPKLFTLSIVDRAIMALLSNIEGSQQAKPSRYRATKEEKEAELAQKIQLAVSYWNAVSSFIPDWQLVLHKQVAAGEIRRDCVHCHSVVLESLGEVGASLRSAFPDGWEERLAALRQVDWSISNPDWEGGILVKGRVLRSRASVSWMTDYLKNRLGLGTADGARAGRPCHNQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F405</accession>
    <name>A0A2G4F405_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1768 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O = 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23436"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:137796"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-amino-6-(5-phospho-D-ribosylamino)uracil + H2O = 5,6-diaminouracil + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:55020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:46252"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56479">
        <property type="protein sequence ID" value="PHX56479"/>
        <property type="gene ID" value="CP500_005155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="SSF143990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02464">
        <property type="entry name" value="ribofla_fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="3">
        <location>
            <begin position="5"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="161" mass="18484" checksum="5DF55F9E4E534863" modified="2018-01-31" version="1">MTIYFFTADEKPHGCFCNFSLHGFELDGLWWHTSEHYYQAQKFSGTAHAEKIRLAKTPADSALLGHAHRHRNDWKQIKYDVMHLAVLRKFQTHADIRKILLATGDELIIQKDIGDYYWGCGKDGSGKNYLGKVLMEVRGTLRCIGSNEMVLRKSENIIQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4G7</accession>
    <name>A0A2G4F4G7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56377">
        <property type="protein sequence ID" value="PHX56377"/>
        <property type="gene ID" value="CP500_005830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="137" mass="14505" checksum="2B71FD4084856C37" modified="2018-01-31" version="1">MFKTVLFPVDQSREAREAAEKVVNIVKTYGARLVILSVVEPPAEAGESPPREAMASPEAVAKLLSDAQAMFSQQGIQAEIIEREGKPAFTICDVADEIGADLIVMGCRGMGLTDDGASDSVTSRVINLSPCSVLIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4H8</accession>
    <name>A0A2G4F4H8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_004040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56672">
        <property type="protein sequence ID" value="PHX56672"/>
        <property type="gene ID" value="CP500_004040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032171">
        <property type="entry name" value="COR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020859">
        <property type="entry name" value="ROC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16095">
        <property type="entry name" value="COR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="23"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51424">
        <property type="entry name" value="ROC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Roc" evidence="4">
        <location>
            <begin position="623"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1272" mass="141097" checksum="01EC9DC8F22AD9AA" modified="2018-01-31" version="1">MTREELLQLIDKAADEGQTELDLAGLGLEELPPEIGKCTQLETLVLGKYDEEKQEFIGNKLTEFPDAVLQLTNLKILNLSSNQITVIPEAIGQLSNLTVLSLYNNQITVIPEAIAQLSNLTGLDLSSNQITVIPEAIGQLSNLTVLGLHSNQITVIPEAIGQLSNLTELDLSSNQITVIPEAIAQLSNLTELSLHNNQITVIPEAIAQLSNLTVLDLSSNQITVIPEAIGQLSHLRGLDLRSNQITIIPEAIRQLSHLRGLDLRSNQITIIPEAIRQLSHLRGLDLRSNQITIIPEAIAQLSNLTELYLNSNQITVIPEAIGQLSNLTRLDLSSNQITVIPEAIGQLSNLTKLNLNSNQITVIPEAIGQLSNLTGLGLHSNQITVIPEAIGQLSNLTGLYLFSNQITVIPEAIAQLSNLTKLYLYNNQITVIPEAIAQLSNLTGLGLSDNQITVIPEAIGQLSNLTLLYLYSNQITVIPEAIAQLSNLTELSLFSNQITVIPEAIGQLSNLTELYLSNNQITVIPEAIGQLSNLTELSLHNNQITVIPEAIGQLSNLTGLDLSSNQIETIPECLETLPKLEKLDLRRNPLPISPEVLGPVNLSEDPGTPATIFNYLRQLRSGEVLPLNEAKVLLVGQGSVGKTSLINRLTHNQYNPNQPQTDGLNITDWQITVNTKPVKLNVWDFGGQEIYHATHQFFLTKRSLYLLVCNCRTSEDENRLEYWLKLIESFGDASPVIIVGNKCDEQPLDLNRKALRDKYPNIKAIIETSCQSGTGIDELRSAIHTEISQLKEVYDLLPLSWFQVKQRLENLDKDIISISEYASICGKENIWEETDKTQLIGLLHNLGIVLNFREHPILQSTNILNPHWVTEGIYALLSDDALKVKTKGILTYDDLSRILDSTKYPSHHYRDLTELMGEFQLCFLVSHCSAPTFLIPGILPKEEPEHTELEGETLEFQYHYGILPDSILSRFIVLTHEKIHNSTHWRTGVMLEYTEGAEVYNIARIKSDPEDEKISIAVSGRESTRRSFLSMIRDTFTKIHNSFANLEISQWVPVPGYPDADPLDYEELLGLEEMGENTVRVGKLKLKLDLRPLLDGYEAIELRRRRQMGDEKYGREYDDIIDIAKLAVSRPIINKAEAKVMTQDSSKTNNFNGPMSGVIGSDNAQVSNNEFIQNNNANTAEILKLISSMRETATQFPEDIRDGVIIDIEDVEAEIKKPESQWNRDRLKKSLTAMIAAATAIAIPIAGMTDFASSAIDLGKKVGIELKLPSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4R6</accession>
    <name>A0A2G4F4R6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pstB</name>
        <name evidence="6" type="ORF">CP500_005200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56487">
        <property type="protein sequence ID" value="PHX56487"/>
        <property type="gene ID" value="CP500_005200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="32"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="283" mass="31663" checksum="03BE2A314E4D9B1A" modified="2018-01-31" version="1">MKPETNLKDEKYTDQFSEDSTPEIDPNAMPALRVQDLSFYYGTHKVLENLSMNIPHPQVTAIIGPSGCGKSTFLKALNRIGELEGKVIIKGRVEFFGQDIYSPKVNINSLRRQIGMVFQRPNPFPLSIYDNIAYGVRIFGKKSKSELDEIVESALKSAALWDEVKDSLNKSAQGISGGQQQRLCIARALAVKPKILLMDEPCSALDPISTMKIEELFQTLRQQLTVVIVTHNMQQAARVSDYTAFFNTDESRIGRMIEFGPTSRIFTSASNASTRDYIQGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4S8</accession>
    <name>A0A2G4F4S8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56735">
        <property type="protein sequence ID" value="PHX56735"/>
        <property type="gene ID" value="CP500_003750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018449">
        <property type="entry name" value="NIL_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09383">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00930">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIL" evidence="2">
        <location>
            <begin position="36"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="13604" checksum="0E25D4A9703388E4" modified="2018-01-31" version="1">MLDQNISESEFEPIDNFHKTQDSDIPKSDSGDTRQTQTRIRIRVPKEYHQEPVISNLISEYGLTVNFNAALLGVKTSDDGWFDLELNGTTQQIDSALIYLNDLDVEIWSNSNNPVEESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Y2</accession>
    <name>A0A2G4F4Y2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hemolysin activation/secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56832">
        <property type="protein sequence ID" value="PHX56832"/>
        <property type="gene ID" value="CP500_003275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005565">
        <property type="entry name" value="Hemolysn_activator_HlyB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013686">
        <property type="entry name" value="Polypept-transport_assoc_ShlB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08479">
        <property type="entry name" value="POTRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03865">
        <property type="entry name" value="ShlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POTRA_2" evidence="3">
        <location>
            <begin position="125"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="ShlB" evidence="2">
        <location>
            <begin position="279"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="633" mass="70234" checksum="7351C028436DE233" modified="2018-01-31" version="1">MVNKGNQKKGDRLLQIAVGVLASNWMVLPLKAQTVPLFPVEFTAQTPIETQTPNLSEPLAPQTVPSQPNLPQPEPSPSLQRQTEPNSDTSEVYECPIARSAEPQSPTTQTPEDSKTNEVIEAISVTNFRFIGNTVFSQKTLEQEISNKLLKLDSNTNRITFPQLQQLISEVTKLYNDRGYINSFAYIPSTSEEPNQRLQNRGAAGEVIIKIVEGGLESIRVRRKTGKQRLNLNYICSRLDMASQPLQVSRLLDALRLLQLDPLIKSISAELIHGSDFQRSALEVKFEEEKTFSAALLLDNRRAPSIGSFRRQIQLTEANLLGKGDGLSLAYTNTDGSNAFDLSYTLPLNPHNGTINLSAGITGNRVIEKPFEKVDIRAAAQYFDLTFRQPILRNPRQELALGVTATRRESGTSILGEDFPLSAGADAKGRTGISAVRFFQDWTVRNNDELLALRSQFSLGLGAFNATINSEAPDSRFLAWRGQGQWIRRFRRDTFLVAKTDVQLANRTLLPLEQFGIGGGNSVRGYRQDILLADNGISASAELRFPIVGRSDRGLGVLQIAPFVDAGTVWNSSGMENSERQFLMSVGTGLRWELGDSMSANFYWGIPLVDVNSRGRTWQEKGLHFSVLSRFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Z6</accession>
    <name>A0A2G4F4Z6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56567">
        <property type="protein sequence ID" value="PHX56567"/>
        <property type="gene ID" value="CP500_004790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="137" mass="15934" checksum="FBB80C4C25F869E0" modified="2018-01-31" version="1">MFDLLHPLHRLFDFWCGNPHQAQDFVPVAEWTEAQWREARVHLHPQLRTSQVREDLMNCIDSQTPFEISRYIIVPTLAPIAIDCTMAACLLPLWDGPQSVLSLVEEWLQIRSQMAVKLEPVSEQTAFEEVKELLIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F506</accession>
    <name>A0A2G4F506_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HEPN_MAE_28990 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56883">
        <property type="protein sequence ID" value="PHX56883"/>
        <property type="gene ID" value="CP500_003150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040788">
        <property type="entry name" value="HEPN_MAE_28990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18737">
        <property type="entry name" value="HEPN_MAE_28990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN_MAE_28990" evidence="1">
        <location>
            <begin position="10"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="219" mass="25030" checksum="EF58F47D175D2C48" modified="2018-01-31" version="1">MSIRTAEQLSDKLSTDLAWRKKELSEIKSLVEARNVSPQRHNALIRSGICILYAHWEGFVKLASNSYLEYVAMQKLRYDQLSSNFLALAMKTKLNEARDTNKPSLYIPVCDFFLSNLNTKCSLPYKDKDAISTASNLSSDILKEITCTLGIDFSVYSTKSVLIDIKLLKTRNEIAHGNYLTVDREEYIELHTEIMGMLDVFRNQIENAAVNKDYMRNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F522</accession>
    <name>A0A2G4F522_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56587">
        <property type="protein sequence ID" value="PHX56587"/>
        <property type="gene ID" value="CP500_004805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="20"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="22044" checksum="3D69F7315457F462" modified="2018-01-31" version="1">MTQTLLRPLDQRFIHSGISWQQFKLIQQGFSDSPGIKLFYYKGEVEILAVSPEHEFFSRTICTLLSIYCAENEIEFAPTGSFTQEKEGVVSVQADESYFIGRRITPNSPPDLCIEVVFTSGNVKKMQRYRVLGVAEVWFWEDGVLAMYRLGSEGYEKISSSVVLPDLDINLLCRCLLMASSVEAMREFRRGICG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F545</accession>
    <name>A0A2G4F545_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">dnaJ</name>
        <name evidence="11" type="ORF">CP500_003345</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DnaJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56845">
        <property type="protein sequence ID" value="PHX56845"/>
        <property type="gene ID" value="CP500_003345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="9">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="10">
        <location>
            <begin position="136"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="149"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="192"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="206"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="7">
        <location>
            <begin position="136"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="377" mass="40961" checksum="62743FA5270AF304" modified="2018-01-31" version="1">MAGDYYEILGVSRSADKEEIKRAYRRLARKYHPDVNKESGAEDRFKEINRAYEVLSEPETRARFDRFGEAGVSGAGAPGFQDFGDSFADIFESFFQGFQGGPGGQQQQQGRRRSGPVRGDDLRLDLRLEFREAVFGGEKELRIKHLETCETCSGTGAKPGTRPQTCSTCGGGGQVRRATRTPFGSFTQVSVCPTCNGTGQVIEDKCDTCGGRGQKEVMKKLKITIPAGVDNGTRLRVSNEGDAGKLGGPPGDLYVFLAVSEDPVFKREGTNINSEVTISYLQAILGCRLEVETVDGPTELLIPTGTQANTVLTLEKKGVPRLGNPVSRGDHLIVVSIEIPTKVTTEERELLMQLAKLKGDRTGKGGLEGFLGNLFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F553</accession>
    <name>A0A2G4F553_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplJ</name>
        <name evidence="5" type="synonym">rpl10</name>
        <name evidence="7" type="ORF">CP500_002990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56855">
        <property type="protein sequence ID" value="PHX56855"/>
        <property type="gene ID" value="CP500_002990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00362">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022973">
        <property type="entry name" value="Ribosomal_L10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="173"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="202" mass="21691" checksum="7D38B3C82C1E3CB7" modified="2018-01-31" version="1">MGKSLAVKNEIIADLKKTLSESQLAIVIDYKTLTVAEITDLRRRLRPKGSSCQVAKNTLMRIAVEGNETWQPMQELLTGTSAFLFVQEDIGGAIKAYQEFQKASKKTELRGGVMEGRVLREADVKALADLPSKEQLMAQIAGALNGVATKLAVGISQVPTSIARGLKAYAEKDQNGDSVEAEAEAQVEPEAEAQAEAESVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F559</accession>
    <name>A0A2G4F559_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hrp-dependent type III effector protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_002800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the four-carbon acid sugar kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56924">
        <property type="protein sequence ID" value="PHX56924"/>
        <property type="gene ID" value="CP500_002800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037051">
        <property type="entry name" value="4-carb_acid_sugar_kinase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010737">
        <property type="entry name" value="DUF1537"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031475">
        <property type="entry name" value="NBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042213">
        <property type="entry name" value="NBD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17042">
        <property type="entry name" value="NBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07005">
        <property type="entry name" value="SBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SBD_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="NBD_C" evidence="8">
        <location>
            <begin position="265"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="442" mass="48588" checksum="F1CF7BC33AA6654F" modified="2018-01-31" version="1">MSAKPKIIVLDDDPTGSQTVHSCLLLTRWDEETLRLGLRDKSPIFFILTNTRSLTPETAASVTREVCQNLKVAIAAEAIDDFLIVSRSDSTLRGHYPIETDAIAEELGPFDGHFLIPAFFEGGRITRDSVHYLMVNSVETPVHQTEFAKDSVFGYSHSYLPDYVAEKTKGRIQAEQVDRILLADIRHGNLERLMDMTDNQCAVVDCENQSDLDTFAKHILDAASQGKKFLFRSGASILTSLADLGPQPIAADEMAKYVRDGKPGAVIVGSHVKKTTEQLEYLLKEAQTVSIEIDVSHLLEDSPEYRTDLLNKTLEKVRSAHSDDKTPVIYTSRQELQFKNTEIRLKFGEAVSGLLMDIVRGLPGDIGFLISKGGITSNDVLSTGLSLKSVRLLGQIIAGCSVVKTEADHPLFPNLPVVLFPGNVGDSNALATAYKRLSKQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F581</accession>
    <name>A0A2G4F581_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HlyD family secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56932">
        <property type="protein sequence ID" value="PHX56932"/>
        <property type="gene ID" value="CP500_002845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014315">
        <property type="entry name" value="ABC_heterocyst_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02971">
        <property type="entry name" value="heterocyst_DevB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="73"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="102"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="207"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="498" mass="54175" checksum="95D259F689E1151C" modified="2018-01-31" version="1">MNFQNLVKPDKRLVMGLVIAGAATAFYGIYQSVSFSQNPTPLPVETTPPVRKITALGRLEPQGEVIRLGVSQTLNGDRISQLLVKEGDRVKAGQLIAILDAGDRLKSALDEAKEKVKVAQASLAQVKAGAKSGELTAQSATIGKLEAELQGNRAAQQATVDRLQAQWQGDRTAQQATISRITAQWEGERKVQEATISRINAQFQGEKKAQQAAISKLVAEFNNAEAEYLRHQQLVAEGAISKSVMDTKKLAVETSRQQVKEAQANLARINNTATQQLQEGQENLNRINSTAKQQLNEAQANLTRINNTAIQQQNEAEANLKRIKESGGEQLEEAKATLEKIAEVRPVDIEAAQTEINSAIAQVKRAQSELNQAYIRTPNAGKILKIHTRPGEKISDNGIADVGKTEQMVVVAEIYQTDISKIKVGQKATINSQAFSGELPGTVKEIGLKVSKQNVFSNQPGENLDSRVVEVKIHLNPEGSKQVEGLTNLQVQVAIEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5B6</accession>
    <name>A0A2G4F5B6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Single-stranded DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56928">
        <property type="protein sequence ID" value="PHX56928"/>
        <property type="gene ID" value="CP500_002825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02645">
        <property type="entry name" value="R3H_AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034081">
        <property type="entry name" value="R3H_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045735">
        <property type="entry name" value="Spore_III_AA_AAA+_ATPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19568">
        <property type="entry name" value="Spore_III_AA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="SSF82708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="3">
        <location>
            <begin position="523"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="587" mass="64815" checksum="8B2003625B08A8C7" modified="2018-01-31" version="1">MQIKDDLNKLLDIVPDHIRQPLEQHPQRNNLIEIVMDLGRLPEARFPSNAQHLSQTPISKEDLKYCIERVGDFGGDNRAGIEQTLHRISALRNRSGEIIGLTLRVGRAVFGTIKIIRDLVETGQSILMLGRPGVGKTTALREIARVLADDLEKRVVIIDTSNEIAGDGDIPHPAIGRARRMQVSRPELQHQVMIEAVENHMPEVIVIDEIGTELEALAARTIAERGVQLVGTAHGNRIENLMKNPTLADLIGGIQAVTLGDDEARRRGSQKTVLERKSPPTFAIAIEMLERQKWVVHEQVADAIDSLLRGRQPNQQIRSVSDTGEVIITHESGNPPARFPGNSGAPAATVSAIRPVTPLSGWRSAGKMVPMPPPAEKVSANGSPVSETRYFEQLLEESLAVEPVALPGRLSQNVGPNGEDLPLHVYPYGIARHQLEQVISTLNLPIVLTKDIDTADVVLALRSNVRNQSKLRHLAKTRQVPLHTIKASTLPHVARALRRLLDMDDPGIPEIADLSLFAHSASSDELEALEETRLAVEQIVIPKGQPVELLPRSSNVRKMQHELVEHYHLKSDSFGEEPNRRLRIYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5E0</accession>
    <name>A0A2G4F5E0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002380</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX57004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57004">
        <property type="protein sequence ID" value="PHX57004"/>
        <property type="gene ID" value="CP500_002380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030655">
        <property type="term" value="P:beta-lactam antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045155">
        <property type="entry name" value="Beta-lactam_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000871">
        <property type="entry name" value="Beta-lactam_class-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35333">
        <property type="entry name" value="PTHR35333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13354">
        <property type="entry name" value="Beta-lactamase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase2" evidence="3">
        <location>
            <begin position="250"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="429" mass="48594" checksum="BB3D903915545896" modified="2018-01-31" version="1">MKYLTNRWREAVDTGRKPRQKAGFSEKKTALPRRLTNSRRPTNQRPVKSRRRVRKPFARLKYRNILYLILGAIAIGWIITLPFRSRRAIEPPVISPQEVLAPPTIPTPENVVDSSSDPTFTYNIKTPPNPVYSQELQVIVDEAAKIAATKGLPIEPLSISLLDVSNSQAHTSAGYQNQTLRFPASVAKLFWMVGFYSALEKGIITQKESSFTSDLEQMIRISNNDAASRILDKITDTQSGGRLVGEELQAWVTKRNQINTFFQSAGYNNIKITTKNYPIYYLRQEQPIGRDLQLRGDPSQPIRNQVTTDQAARLMYEIYTRQAVSSIASRKMAYLLTRDLDPKAWKNDPSNSIQGFLGESLPTNIYFGSKVGYTSKSRSEVAFVRTLDDRAIYILVVFADDPAYAKDETVFPAISRYVFDRLNARGPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5N6</accession>
    <name>A0A2G4F5N6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57035">
        <property type="protein sequence ID" value="PHX57035"/>
        <property type="gene ID" value="CP500_002280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="9862" checksum="8FEA43A50777D824" modified="2018-01-31" version="1">MPRKKQAQESKDIPALQILREAAGLSQSALAKKIPDKTRTKTLTQQAISKWERGIDEPELTIVQMKALCEALGKTLNDLPNDLGPPNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5S3</accession>
    <name>A0A2G4F5S3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57106">
        <property type="protein sequence ID" value="PHX57106"/>
        <property type="gene ID" value="CP500_001495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="12829" checksum="154021DDAAFF50D1" modified="2018-01-31" version="1">MTQLSEKRKALRGRISPERITPPEELARRKAERTQLGLRCRKIFERIRPELIDEYYNWFIAIEPDTEEYVIDRKFLGIIQKVKEQYTDPDVRLTIFCLNERGTCGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5S5</accession>
    <name>A0A2G4F5S5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56837">
        <property type="protein sequence ID" value="PHX56837"/>
        <property type="gene ID" value="CP500_003300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="55" mass="6394" checksum="A678B6E1AD735C66" modified="2018-01-31" version="1">MYIDNGVSLGLLIDRKNRKVYIYRPEKEPEILDNPETVSGDPELTGFVLRMAKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5X7</accession>
    <name>A0A2G4F5X7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmJ</name>
        <name evidence="6" type="ORF">CP500_001710</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015178722.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57172">
        <property type="protein sequence ID" value="PHX57172"/>
        <property type="gene ID" value="CP500_001710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_L36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_L36_sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42888">
        <property type="entry name" value="PTHR42888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="SSF57840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="37" mass="4394" checksum="DA94AD906BFEF55F" modified="2018-01-31" version="1">MKVRASVKKICEKCRVIRRRGRVMVICTNPKHKQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6A5</accession>
    <name>A0A2G4F6A5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CHASE2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57302">
        <property type="protein sequence ID" value="PHX57302"/>
        <property type="gene ID" value="CP500_000515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007890">
        <property type="entry name" value="CHASE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05226">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01080">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="708"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="734"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="761"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE2" evidence="2">
        <location>
            <begin position="419"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="787" mass="88757" checksum="B0503DDB8F0C845E" modified="2018-01-31" version="1">MSRVAVLKIGVGDFSEGFDISLQFWSDNAPPTEEICGRLPGNLKVRAFYELWHSAYLTLKPPVPNSMRSKNDYSVSEIGQTTNRASSEGVSACRRLARSLEAEMKSWLMSGGTWQPIREGMLKELSNKRGEIRIILQINNPDTVLWKLPWHVWDLLQDENGSDVEIALTSSEFRRAKVLNKTALGKEKAHILGVLGDSTGINVQTDREEVERLSCAEAIFLDEPQPQDFLKQLRSEIGWDIFLFSGHSERVAESGRIYINENSSLEVLDFRNSLREAIGQGLKIAIFNSCDSVGLVRDLAQAGLYIPVAIAMREEVPDAIAQAFLKEFLTEYASGQSLQTSVRRSRDRLEDWEQVWPGVTWLPVICQNPAEVPPTWQQLGNAKKGDRLIKSNWVKLRIALLASLAATSFVIGLREIGWLERVELKAFDTIMRLRPHEGEDPRLVLIEANTEDIKKYGFPLPDGIIAQVLKKIEAYQPLVIGLDIYRDRPIASGNSELVKQLQNDRAIVVCKVKDDKDPGVLPPPSVSNIDRQGFSDLVHDSDNVIRRHLLRLSPDINSPCRTNDSFSLRVALDYLQERYGIEPTDTQYPKLGKVVFKPLQTNLDRPSRAGGYRTTNLRDYQILLNYRSTSNLTSRISIREVLNNKFDPNSIRDRIVLIGVTDPSNSEPDIHLTPYEKMPGVVIQAQMVSQIISAVVDDRHLLSVWPQWGEFLWIWGWSLVGSVLIWSRRKLLEGSVALTVATITLSGICFILLLIQGSWIPLIPSVLALIVSGWIIRVYRVLTSRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6A6</accession>
    <name>A0A2G4F6A6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57288">
        <property type="protein sequence ID" value="PHX57288"/>
        <property type="gene ID" value="CP500_001215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="12"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="21875" checksum="DB1D986A81F70D1F" modified="2018-01-31" version="1">MTTTTATRKLTLEEYLVYDDGTDTKYELIDGELVEMPPETNRNNRIAIYLLSEFLKLVPFYLICCKDTEIVVMGQRTRVRLPDLMILTEELFAAIDGRRATITQDMPPPALVVEVVSPGKVNEDRDYRYKRSEYAARGIPEYWIVDPSQAKVTVLIWVDGLYEEAVFQGSNAIASTTFPDLKLTVAQVLGAGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6C3</accession>
    <name>A0A2G4F6C3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-beta hydroxysteroid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57306">
        <property type="protein sequence ID" value="PHX57306"/>
        <property type="gene ID" value="CP500_000550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044256">
        <property type="entry name" value="HCF244-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47128">
        <property type="entry name" value="PTHR47128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="325" mass="36346" checksum="FDC3F5542DBD4AE2" modified="2018-01-31" version="1">MTLLILGATGTLGRQIARRALDEGYQVRCLVRNYRKAAFLKEWGAEIVPGNLCQPDSLTSALEGVTAIIDAATASATDSVSIKRVDWDGKVSLIQAAVAAGVKRYIFFSFLDAEKYPQVPLLEIKHCTELFLAESGLDYTILRPCGFLQGLLSLYAMPILDSQGVWLPNKPSALAYMNTQDVAKFAVRALSVPETEKKSFPMVGTRAWDAEEIVRLCERLSGKQAKITRTPDALLKATRQFASFFQWSWNVADRLAFSEVLAAGKPLKAPMDQVYSVFGIDPKETTTLESYLEEYFSLITKKLKEIEYEQLKTKKRSKQKMPFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6C4</accession>
    <name>A0A2G4F6C4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57322">
        <property type="protein sequence ID" value="PHX57322"/>
        <property type="gene ID" value="CP500_000645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013579224" evidence="1">
        <location>
            <begin position="24"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="141" mass="15613" checksum="E7ADA22945DA5406" modified="2018-01-31" version="1">MKSKLFWSLCTVVVASLPMPSFAQTKPVEVRFDYKGSSLKYQVLPGAIPNRTLPKAFDFPIITNVVTDTSVTSDYLITNEFRAPATRQEYTSALNTWAGAVKECLVNKKPRLIRASTKNPVLFDGKAGTIVRNANNRAVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6K5</accession>
    <name>A0A2G4F6K5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57423">
        <property type="protein sequence ID" value="PHX57423"/>
        <property type="gene ID" value="CP500_000355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="8068" checksum="991DD779A03CC874" modified="2018-01-31" version="1">MQVETWQRTTQEVQAKLDATQSEKEWVKSQLNSWKQTAEEMQLELDRSRSKLKQAQSQLDRSGFPIGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6L2</accession>
    <name>A0A2G4F6L2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CP500_001635</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57127">
        <property type="protein sequence ID" value="PHX57127"/>
        <property type="gene ID" value="CP500_001635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007892">
        <property type="entry name" value="CHASE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05228">
        <property type="entry name" value="CHASE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 11" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HAMP" evidence="17">
        <location>
            <begin position="319"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="15">
        <location>
            <begin position="377"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="16">
        <location>
            <begin position="450"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="699"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="999"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="1146"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="18">
        <location>
            <begin position="1339"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="350"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="11">
        <location>
            <position position="1049"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="11">
        <location>
            <position position="1195"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="10">
        <location>
            <position position="1378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PHX57127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1444" mass="160331" checksum="8C1871C0391BA06B" modified="2018-01-31" version="1">MQLRKKTLLIVGAALICLIVVLYATASTILLHDFHNLEAQYVRQDVARALDTLDDDLSNLDTSAQDYAEWDDTYSFVNTQSQDFVKSNFVDSTFVYLRLNLLVVLDSKGETVFSKGFDLKSKTQTPIPESLKQHLTATLLDSRTDSGGVLRAKTGVLTLPEATLLVSSKPILNSNAIGPPRGTLIVGRYLDNSEVELISRLTHLSVDFRLPSLDFKVESTSDYWPSAKTIVKSQQELENLKIRISNLKSVEILVAPLSNSLVAGYALIRDINGKPGLMLRVEVDRVIYRQGQATLELFTLSILAVGLVFSAIALLLLEKLVLARLQDLSTSVRNIATNGDPDLRVHMSGADELSSLAETINQMLEALNDSQAERNESEDRYRLMADNSTDMISRHNPKGIFVYVSPACKALLGYEPEELVGRVPKDYFHPEDLQKLAKAHIKLMSLAVTYTLSYRIRRKDGKYIWFETTSRTIRDEVSGEVQEIIGISRDISFRKETEQELRESEAAIKALYQVTSAPRTDPLNRLWAFDLRLQELLTMGCRQFGMEVGVLSAIEGENYQIRAAKCPDDSIAIGQVYDLQKTFCVATAKSKEPLHFESVRFLSLSFDGDCPSFNNESAFNIESYMGIPVLVAGKVYGTLCFWSATPLTEPFRVVDRELLKLMAQWVASELERQQSGIDLAKARDEALAATRVKSEFLATMSHEIRTPMNGVIGMTGLLLDTRLTSEQQDFVETIRSSGDALLTLINDILDFSKIESGKFDLEEHLFDIRTCIEESLDLVAARAAQKKLELGYLIDGSLPATAIGDSTRLRQILINLLSNAVKFTESGEVVVSCTAKKMPMPLSIATQQPELLESEQSKIHQIYEIQFAVKDTGIGIRGDRMNRLFKSFSQVDSSTNRHYGGTGLGLAISKRLAEMMGGRMWVESGGNLAGNPPEGFKSTVLDRELVANCDRLKLTEIDTQTNNLKSVGSTFYFTAIVPCYNCSLPINLSNSQPELAGKRVLIVDDNATNRQILTLQTQSWGMVPTTVASARLALNLLAAKEEFDLAVLDMQMPEIDGLTLAVQIRMSEAGAQLPLVMLTSMGRQEIRTPVIEVNFAAFLNKPIKQSQLYNVLINIFGESTGEVRVQRSSGRLSKSIPMIAQELPLRILLADDHLVNQKVGLQILQRMGYRADVAGNGKEVLEALRRQPYDVILMDIQMPEMDGLEASRLICQEWEAAAKPWIVAMTANAMRGDREECIAAGMDDYLSKPIEIDELVRVLRGCQSRSPIEFDRWQSMISASSNAEEIGKNELEVRSNLTVADNPQLTIVDAKPAPSQSFTEDAPEDNKCLSQKILDGLREVEALDEVIEIYLETAPQLLLGISGAVNSADPLALRRSAHSLKSISGTLGAFRLFELCEELELMGRMGTDANKSLPPKARAVLEQVEAEYQRVEAALKMELLYSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6P5</accession>
    <name>A0A2G4F6P5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymethylenebutenolidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57385">
        <property type="protein sequence ID" value="PHX57385"/>
        <property type="gene ID" value="CP500_000120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="20"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="248" mass="27035" checksum="FD891B6E5A234DD1" modified="2018-01-31" version="1">MTNSEIRTKNITIPNGDLQIAAYLAQPAAAGKFPAVIVIQEIFGVNSHIREVTDRIAKEGYVAIAPAIYQRQAPGFETGYTPEDIKIGREYKEQTTASELISDIQAAIDYLKTLPFVKQSGFGCIGFCFGGHVAYLAATLPEIKATASFYGAAIATQTPGGGPPTIDRTAEIKGTIYGFYGTQDASIPSEQVDQIATELEKHSIPHLIFRYNADHGFFCDHRGSYNATAAAESWEEVKHLFQQELQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6T0</accession>
    <name>A0A2G4F6T0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FkbM family methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000345</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57421">
        <property type="protein sequence ID" value="PHX57421"/>
        <property type="gene ID" value="CP500_000345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="3">
        <location>
            <begin position="32"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="638"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="816" mass="93358" checksum="0575E6C646C37FC6" modified="2018-01-31" version="1">MRVEACCQRILSHVLPIVDGNREGICIDVGVGTFAFYCEMFAMLGFKTIAVEPLPVEGVRVLCRYDSINLIEACLSDVNGTKTIHLGNVAAGLDSNYASLEPDWFGVSTETLEVQSLTLSKLLLNLNAGKVTCLKIDIEGAESTVIKTFRELPQAWLPSVVMFEYGGGAGTKKTGQHGWSPKFFSATMECLNVLKECGYGFSVMVDNALDTEAKVFDLQTSNLEPDNIFYQNGGYGNIISFRKLTLPEDEVRKICSPYYEISASNSTNIATGDNVAKSPGSEEAEVYKFQLHLLREELAQCKGELQQLRSHSQSQLHQAQGELEQYQSQLHQAQGELEHSQSQLHQTQEVLEQFQDQMQQAETLLQDYQGQLHQTQTELEQSESKLHQTHAVLEQSESQLHQTQSELQESKEELGEFQTIAEQLQEQLHQTHAVLEQSQGKLHETQTELAQTKSQLYQTHEELEQSVSQLHQTQSELQESKEELGEFQTIAEQLQEQLHQTHAVLEQSQGKLHETQTELAQTKSQLYQSQWEEEKSRFQLHQTQAELANSQSELHQIKAQLQHSQSQVDETQSLFRHSQSQVDETQGLLRESQSQLYQNKNELKRVYHQLYHLQGEWEQSQLEVKQSQTVLKKFQSQIHENRSELKQAYSQIHQLQGELEQSQSQFSQTQQVLEQSESQLHQTQAELEQSESQLHQTQGEVEQLKSQFSQTQVELVRTRLQHQDVTTEPQSTATEYKLLVWDAWYAYQSGDLKKMQQCLQESLKFTPISRTESVVNWLECFAKFSSEKGHDFDSYALTNSQEWKRLIQQRVTVSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUQ3</accession>
    <name>A0A2G4EUQ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000228">
        <property type="protein sequence ID" value="PHX53261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53261">
        <property type="protein sequence ID" value="PHX53261"/>
        <property type="gene ID" value="CP500_022470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="8786" checksum="AB4CF7B1AD09C5BD" modified="2018-01-31" version="1">MCQLGVRNVGLNVAHQKGKATDLIEYFAAPENQDLGIVKSQRKPNVKLIVSPFPDRQRGNHQFFFDASSEIPFTTGIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUU8</accession>
    <name>A0A2G4EUU8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyanoexosortase B system-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000219">
        <property type="protein sequence ID" value="PHX53305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53305">
        <property type="protein sequence ID" value="PHX53305"/>
        <property type="gene ID" value="CP500_022220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030917">
        <property type="entry name" value="Cyanoexo_CrtB_assoc"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04533">
        <property type="entry name" value="cyanosortB_assc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="236" mass="26825" checksum="1A6A40F8A0FD37DD" modified="2018-01-31" version="1">MEQMISARKLLRRYQLSKIIVLVFLLVLVGLIAIPGYGTGRWPWTNPPPVANLKQLKILRQNGLTLPGWQTLRTQNHVLIGGHKWLVEEIKNDQTIAVLLLLPQNGPKDQPQVEWLDIKGFHRWQTDSDRTLSFTVNLTSVANTQTTTVTARFFRSRTPQQTFAVLQWYAWPNGGSPSTSRWFWEDSIARLSNRRASWVAVCIIVPIQPNADIKIAEPILNSLGKIVQAKLMAETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUX7</accession>
    <name>A0A2G4EUX7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nitrate ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ntrB</name>
        <name evidence="8" type="ORF">CP500_021985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000211">
        <property type="protein sequence ID" value="PHX53343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53343">
        <property type="protein sequence ID" value="PHX53343"/>
        <property type="gene ID" value="CP500_021985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005889">
        <property type="entry name" value="NtrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01183">
        <property type="entry name" value="ntrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="85"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="289" mass="31849" checksum="EFFA40E62E821C11" modified="2018-01-31" version="1">MATNLSISKSKNPVTFILNLVQKNRQKIIRPLVAIAVLLIIWQILCHSPESTLPGPIKAVQESWELIVNPFFDRGGTDKGLFWQLLASLQRVAIGFTLAAVLGISLGILIGTNSLMFDALDPLFQVFRTIPPLAWLPIALAVFQQFNPFEGLGMKANEVSALFVILITAIWPILINTTVGVQQIPQDYRNVARVLRLPNQKYFWKILLPSSVPYIFTGLRIGIGLSWLAIVAAEMLVGGVGIGFFIWDSYNSSRLSAVILAVVYVGIVGLILDRIVGFIASKVVPEEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV96</accession>
    <name>A0A2G4EV96_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fmt</name>
        <name evidence="11" type="ORF">CP500_021745</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="NXIB02000204">
        <property type="protein sequence ID" value="PHX53386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53386">
        <property type="protein sequence ID" value="PHX53386"/>
        <property type="gene ID" value="CP500_021745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="206"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="111"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="342" mass="36633" checksum="3729D9F41227BFAC" modified="2018-01-31" version="1">MKIVFFGTPEFAVPTLSSLLSHPDFEVVAVVTQPDKRRGRGNQLMPSPVKMAALNHSIPVLQPSRIKKDVEIIAKLREAEADVFVVVAYGQILSQEILDIPSLACVNVHGSILPKYRGAAPIQRCIYDGEKETGITTMLMDAGMDTGAMLLKDFAGISLLDNADSLGDRLSEMGADLLVETLVKLRDGKIEAVPQDEADASYAPMIKGADFVLDWSKSAIALHNQVSGFYPDCTTSFRGNSLKVMATVPVGPEYWLQMPADLRVLERDWAVLSELSGENGAVVKVVKGLGAIVQTGNGLLLLREVQLAGKKVQSGVDFANGTRLLVGEVFGAVAIGDGNALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVC9</accession>
    <name>A0A2G4EVC9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="19">DNA-formamidopyrimidine glycosylase</fullName>
            <ecNumber evidence="19">3.2.2.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CP500_021190</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.23" evidence="19"/>
    <dbReference type="EMBL" id="NXIB02000188">
        <property type="protein sequence ID" value="PHX53502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53502">
        <property type="protein sequence ID" value="PHX53502"/>
        <property type="gene ID" value="CP500_021190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020629">
        <property type="entry name" value="Formamido-pyr_DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00577">
        <property type="entry name" value="fpg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14 19" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="18">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="17">
        <location>
            <begin position="221"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PHX53502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="255" mass="28231" checksum="AAF4214BFE360EF8" modified="2018-01-31" version="1" fragment="single">GREGEFQGETPGNSELPSFLFPLPSSRHPLHPLQNPLPNFPLPSSQTGWLGVHLRMTGQLLWVNSDEPLPKHTRVRLFLEGNQELRFVDQRTFGQMWYVPPETEVSSVITGLKVLGPEPFSAQFSVPYFAQKLHRRARPIKTALLDQSLVAGLGNIYADETLFVAGVLPTTLCADLTAEQIERIHAAIVQVLDKAIASGGTTFSNFLNVQGVNGNYGGVAWVYNRKGQPCRTCDRAIERIKLAGRSTHFCPVCQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVE4</accession>
    <name>A0A2G4EVE4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000187">
        <property type="protein sequence ID" value="PHX53504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53504">
        <property type="protein sequence ID" value="PHX53504"/>
        <property type="gene ID" value="CP500_021145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="6622" checksum="BE092558D58FCE15" modified="2018-01-31" version="1">MLNLTSEGNTCYVASAISRLNPHKVFRHQKPKQNKDLQSCPVKMFVVVSGCASTIKSVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVM2</accession>
    <name>A0A2G4EVM2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphopeptide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000190">
        <property type="protein sequence ID" value="PHX53490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53490">
        <property type="protein sequence ID" value="PHX53490"/>
        <property type="gene ID" value="CP500_021220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FHA" evidence="4">
        <location>
            <begin position="178"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="263" mass="27581" checksum="07094543C4727278" modified="2018-01-31" version="1">MIVCPNCNHQNPDGANQCEACYTPLPVTTSCSNCGAAVQTDAAFCGQCGFNLRPGSSVPENEANVELASSVGATVVSPLIPDLVSPEPLMVPETIVTANVGPNLEKTPVSIPPIVPDPPLSSSVPVTTESVASSVNTPPVANQPPAGVANTQLQQQSARLIHVQTNTLIELPHNLSVIHIGKPNDMVPPDIDVAGFANSEIVSRVHANLRVEADACYLEDMGSSNGTYVNNTPLPKGNRHRLRPGDRISLGKGDLVTFLFQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVR1</accession>
    <name>A0A2G4EVR1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carboxyl-terminal protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021035</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000183">
        <property type="protein sequence ID" value="PHX53530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53530">
        <property type="protein sequence ID" value="PHX53530"/>
        <property type="gene ID" value="CP500_021035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="100"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="416" mass="45044" checksum="B7DE0476B96346B7" modified="2018-01-31" version="1">MHRRVFQMAILFVLQVALVFGSWAQPAMALTDEQKLLNEAWRIVNRSYVDDTFNHKNWRSIREKVVKAPLNDRPQTYTAIQEMLANLDDPFTRLLKPEQYRSLQVNTSGELTGVGLQIAIDPQTNTLTVIAPITGSPADRAGIQPLDRILKIDGTPTSELSLDEAATKMRGRVGTPITLTLGRAGRDSPEDIQLVRARISLNPVYAELQSGPENSPLGYIRLSQFSANATAEVAHAIDRLEKQGAAAYILDLRNNPGGLLQAGIEIARLWIDSGTIVYTVNRQGILGSFEASGQALTGDPLIVLVNKGTASASEILAGALQDNGRAQLVGEKTFGKGLIQSLFDLSDGSGLAVTVAKYETPNHTDINKLGIAPDRVVPLESITRDQIGTEADLQYQAALQLLKQKTIMASGMGQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVY5</accession>
    <name>A0A2G4EVY5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000162">
        <property type="protein sequence ID" value="PHX53693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53693">
        <property type="protein sequence ID" value="PHX53693"/>
        <property type="gene ID" value="CP500_020170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="8976" checksum="A8A8A0F2B1A0FE9D" modified="2018-01-31" version="1">MLVWAGRVYETVGFDRVLLVNPPLQDFALYNNDAVDLCLYGQGGFMKLLALIENNGIARRYKTLDYITMMLPDMILLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW21</accession>
    <name>A0A2G4EW21_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable 30S ribosomal protein PSRP-3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ycf65-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_020185</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Probably a ribosomal protein or a ribosome-associated protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the chloroplast-specific ribosomal protein cS23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000163">
        <property type="protein sequence ID" value="PHX53678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53678">
        <property type="protein sequence ID" value="PHX53678"/>
        <property type="gene ID" value="CP500_020185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00619">
        <property type="entry name" value="Ribosomal_plastid_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038447">
        <property type="entry name" value="PSRP-3/Ycf65_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006924">
        <property type="entry name" value="Ribosomal_PSRP3/Ycf65"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35108">
        <property type="entry name" value="PTHR35108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04839">
        <property type="entry name" value="PSRP-3_Ycf65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="12253" checksum="B91F7DFA759A79D7" modified="2018-01-31" version="1">MGTPEVCLSKFILKVLWLEENVALAVDQVVGKGTSPLTAYFFWPRKDAWEELKNELEAKHWIADNDRVEVLNQATEVINYWQEEGRRRPMPEAQSKFPLVTFTGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW37</accession>
    <name>A0A2G4EW37_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000203">
        <property type="protein sequence ID" value="PHX53397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53397">
        <property type="protein sequence ID" value="PHX53397"/>
        <property type="gene ID" value="CP500_021740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7106" checksum="2083487627E85324" modified="2018-01-31" version="1">MGREFYLGVLGIGHGELGMGHWAWGIGHGALGMGNWAWGIGHGCQLKVKPIVRQGLKPLSQSESPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWB3</accession>
    <name>A0A2G4EWB3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IV pili twitching motility protein PilT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_019415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000152">
        <property type="protein sequence ID" value="PHX53823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53823">
        <property type="protein sequence ID" value="PHX53823"/>
        <property type="gene ID" value="CP500_019415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="3">
        <location>
            <begin position="216"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="375" mass="41868" checksum="1E02188470314452" modified="2018-01-31" version="1">MAPPEPAPQSFAPPKDSSSENTGNPTLRQLVQRAKEESVSDLHLGVNEIPRFRKRGEITDAGYPTTDLDVFMGWLRECMTDDEIAYFQKNLDFDGAFDFGFVRIRISAFDSLAGPAMVLRLIPAEILTMEQLKLPEVFRKICGYHKGLILVTGPTGSGKSTTMAAMIDYINKNNSHHIITIEDPVEFVHTSKKSLIKHREVGRHTLKFVNALKGALRQDPDMMLVGEIRDRETVEIALKAAQTGHLVAGTLHTNSAVKTLNRILDMFASEEQPALRVSIAESLLAIIAQMLCKTTDGKRAAYHDVLINTDVVKEFIMKGKNEEINQIMIKDTYEGMTTMNKSLYGLYQEGRITEEICLAQSPSPNEMGQMLRGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWF6</accession>
    <name>A0A2G4EWF6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterioferritin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000154">
        <property type="protein sequence ID" value="PHX53796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53796">
        <property type="protein sequence ID" value="PHX53796"/>
        <property type="gene ID" value="CP500_019595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="1">
        <location>
            <begin position="3"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="16573" checksum="6373403EFC2D6788" modified="2018-01-31" version="1">MKELDEKKTQELLCTIMEWELAGVVRYTHYALMVTGPNRIPIVQFFQAQATESLLHAQQAGEILTGLDGHPSQKIAPIEETYKHSIKDLLEESLNHEKKALDKYKSLLEVVTDASVYLEEYARTLIGQEELHQVELKKMLRDYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWJ1</accession>
    <name>A0A2G4EWJ1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec-independent protein translocase protein TatC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">tatC</name>
        <name evidence="6" type="ORF">CP500_019000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Forms a complex with TatA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53903">
        <property type="protein sequence ID" value="PHX53903"/>
        <property type="gene ID" value="CP500_019000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019820">
        <property type="entry name" value="Sec-indep_translocase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01840">
        <property type="entry name" value="TATCFAMILY"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00945">
        <property type="entry name" value="tatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01218">
        <property type="entry name" value="TATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="276" mass="30205" checksum="9C020591E45146BB" modified="2018-01-31" version="1">MTSPSDLETSEQNFDNNLEPSIMPIAEGFMGSRNLENEFLDELPDEVEMSLFDHLEELRLRIFYALIAVVIGIVGCFLYVRPIVKLLEVPAGSVKFLQLAPGEYFFVSIKVAGYSGLLIASPFIFYQIALFVLPGLTRKERGLLGPVFFGSSFLFLGGLVFSYIALIPAALNFFVTYGADVVEQLWSIDKYFEFVLLLMFSTGLAFQIPIVQVLLGVLGIVSSKQMLSGWRYVILGAAVLGAVLTPSTDPLTQSLLGGAVMALYFGGVGLVKLLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX98</accession>
    <name>A0A2G4EX98_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54151">
        <property type="protein sequence ID" value="PHX54151"/>
        <property type="gene ID" value="CP500_017650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="13579" checksum="DA09CAB44AF0FFAC" modified="2018-01-31" version="1">MVTSLNVLQSQPSSQWKVTLLLETLSSGQVSASVFEFPHCRVEAATREEAITQLQTTLLERLKHIEAISWEVPIQASEPTWMQFAGVFKDDPDFQEIMDEIRAERTSDDDSEIDPSYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXB9</accession>
    <name>A0A2G4EXB9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245736">
        <property type="entry name" value="C.Tbo703ORF17435P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54192">
        <property type="protein sequence ID" value="PHX54192"/>
        <property type="gene ID" value="CP500_017425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="7997" checksum="EFD8A5E5A43AC0C0" modified="2018-01-31" version="1">MDITEQFGKKVRHFRKLRNLSQDQLAELSELHRTYIGSVERGERNITLLNANKIAKALSVSLAELVTDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXE5</accession>
    <name>A0A2G4EXE5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54199">
        <property type="protein sequence ID" value="PHX54199"/>
        <property type="gene ID" value="CP500_017460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="8"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="282"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="356" mass="39595" checksum="ED5928E44D3A9262" modified="2018-01-31" version="1">MVSLNSKIGVIGAGTSGVYLAILLIQRGFQVTLFEKAPHPRTDGCGILIVQAGMEALHQGNHQVTQKIINSGDAVKVFEFRNLRGGVINSEPVTYEENELPGMLVHRKAILEALLDELPPDCIRFNADLLSIAQTEHSAIAHFKDGTHWEGDLLIGADGILSKVRQFIVPNVELFYLGDIVWRGIVEDSSFCPEGNFFVYVRGRGIYANFFHIGGGRTHWGFFIEKERQESEVGKLQPNDIIIPPQELAKLPDDARKVIESTPVENIVCRFSYDIDPLPKIYDGHVILIGDAAHAKSSTRARGMTSGWEDGLSLAQHLTDSASIVEALENFQTERLPIVHEYQRTSREMSLKIGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXG5</accession>
    <name>A0A2G4EXG5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_017315</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54225">
        <property type="protein sequence ID" value="PHX54225"/>
        <property type="gene ID" value="CP500_017315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="311" mass="33256" checksum="D13F22A9359D3253" modified="2018-01-31" version="1">MNDFFTTYGFLIVSMLLGAMLGMSLYLPLMTGQLSLASPGFYALGGYIAAILSTTVFKTTEGLFPLPLLLVEMIIAGVVSGLLGILVGIPALRLSGIYLAIATIAFVEILRVLSLNLDITGGAVGIFGIPQPFGTPIEYLWIVLPLLLVSMAIVYRLERIRVGRAFAAIRADELAADAIGINPTFYKVLAFTLGAILAGVVGAVSAHFLNTWNARQGTFDASIIYLTSVLIGGSRTFLGAVLGGMVFTALPEVLRGMATIQGLPIWLAQFLRDGRLIVFGVLIVLGTIFFPQGLVTPELLKKWRKGDRNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXH7</accession>
    <name>A0A2G4EXH7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54252">
        <property type="protein sequence ID" value="PHX54252"/>
        <property type="gene ID" value="CP500_017105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="161" mass="17915" checksum="747542DB9432C5D1" modified="2018-01-31" version="1">MSSEIILRPATRADVPMLFDLIKALAEYEKLSDAVTGNAVDLENHLFGDRPFAEAILAESEGRVVGWALFFHNYSTFLTQPGIYLEDLFVLPEFRGRGIGKSLIVYLAQLTVERGCGRLEWSVLDWNELAIGFYKGIGADVMPDWRICRLAGESLASLASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXM3</accession>
    <name>A0A2G4EXM3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Translation initiation factor IF-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54283">
        <property type="protein sequence ID" value="PHX54283"/>
        <property type="gene ID" value="CP500_016950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="7146" checksum="EAACBC8AEC623CED" modified="2018-01-31" version="1">MGFADLSIAEIAEDFNVPVEDVIRLCNELEIAYKHPQTRLALEDVKAIMSALEKRRDSKLITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXR4</accession>
    <name>A0A2G4EXR4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_016825</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54311">
        <property type="protein sequence ID" value="PHX54311"/>
        <property type="gene ID" value="CP500_016825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="8">
        <location>
            <begin position="2"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="7">
        <location>
            <begin position="282"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="367" mass="42098" checksum="9941C62A4367F5C4" modified="2018-01-31" version="1">MRLFLNPEQKALIKQWFGVSRFVYNTTIKYLQERGAKANWMTIKTGILNSLPEWAKPVPFQIKSIAIKDACSAVKAAKQGFKKDGQLRQCKFRSRKDTKQSIYVPKSAVKNCGVYHSILGKCQLTESLPTNFSDGRLTLTYGEYYLIVSEEVQPTKTDKQGRVVALDPGVRTFMTFFSEDSYGWLGNDSNLYIQKLCFRLDKLVSKISKAPSRQKRRFKKAASRLRCKIKNLSRELHHKVAKFLVDNFDVILLPTFETSQMVSKSRRKLRNKTVRQMLTLSHYEFKNFLKWKAWENSQLVIDCNEAYTSKTVSWTGEIVKNLGGARTIKSAATGLKMDRDLNGARGIFLRALVDTPLLRDSLNLYVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXV7</accession>
    <name>A0A2G4EXV7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">Pyruvate kinase</fullName>
            <ecNumber evidence="6 14">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">pyk</name>
        <name evidence="18" type="ORF">CP500_018495</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 14">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="6 14"/>
    <dbReference type="EMBL" id="NXIB02000133">
        <property type="protein sequence ID" value="PHX53997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53997">
        <property type="protein sequence ID" value="PHX53997"/>
        <property type="gene ID" value="CP500_018495"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 14 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 18" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="15">
        <location>
            <begin position="8"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="17">
        <location>
            <begin position="363"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="16">
        <location>
            <begin position="507"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PHX53997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="595" mass="63660" checksum="B7778095FD5275AE" modified="2018-01-31" version="1">MQLPKSLRRTKIVATIGPATSDPQVLRQLIEAGATTLRLNFSHGTEEDHLRSIRLIRQASFELNQPVAILQDLQGPKIRLGRFETGSIVVKNGEHFILTSRPVPGTELISSVTYEPLADEVPEGAVILLDDGKVEMVVEKVDRNSRELYCRVVVGGPLSNNKGVNFPGVYLSIKALTDKDRKDLMFGLDQGVDWVALSFVRNPQDMLEIKELIASAGKQVPVIAKIEKHEAIEQMEAILALCNGVMVARGDLGVELPAEDVPILQKRLIATSNRMGIPVITATQMLDSMVGNPRPTRAEISDVANAILDGTDAVMLSNETAVGKFPVEAVATMARIAVRMEREGIKGNIRNVEDIGRSITNGISQAVSQISEQLNAAAIMTLTKTGATARNVSKFRPKTPILAVTPHVDVARQLQLVWGVKPLLVLDLPSTGQTFQSAINVAQEKKLVSDGDLVVMTAGTLQGVAGSTDLIKVEMVTAVLGKGTSVGLGSVSGMARVAHTAADVANFHPGDILVVNRTSADFVEMIRKAAGVVTEEESLTSHAAIIGLRLGVPVMVGVENATRIIRDGTMLTLDMQRGLVYSGARGGGTDGELDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXV9</accession>
    <name>A0A2G4EXV9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3800 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54359">
        <property type="protein sequence ID" value="PHX54359"/>
        <property type="gene ID" value="CP500_016525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024524">
        <property type="entry name" value="DUF3800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12686">
        <property type="entry name" value="DUF3800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="31128" checksum="7D6FB215F08286C9" modified="2018-01-31" version="1">MVRFGVTAGVISFWNKVMEFLYMDESGDNGLVEGSTDFYILAGVAIETNYLKELFWIVLNFRQSISQRYGLKIQELKGSDLFAHRGAFFNSLANPVDMEDIYIGIVNILCDSPIQLFATVRSKNEFRNRYSQLNKKSVKLFSEEIWREFLSIYENYLHDKSRATKQSQNGLIYFDRNPSQEKNIRTIVRERFRKFDIQSEYPECGIVEDVVFRDSHSSYFIQLADILAFTVSRLITGRGNNDVFSIKPEIASKLEAKIILRKGKFTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXX5</accession>
    <name>A0A2G4EXX5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54328">
        <property type="protein sequence ID" value="PHX54328"/>
        <property type="gene ID" value="CP500_016775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="81"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="773" mass="85248" checksum="DA88C083BBF94607" modified="2018-01-31" version="1">MSQEFRLSVTPVGDDEYLVRTEKVAPGVPLAEQQVRWPIDQWLDQSAKLMNDPLMGVFEGKASRVFSRSSRNQAPNLVALGQQLHSGLFQGRLRDSWTCAQGIAQHRREVLQLRLGLKDRRLPRLPWEVLHADDRPLATGTDVVFSRYHTGTSLLKPTRIIPSSGPLRILMALASPSDRDSLQLKREVLHLQQELQNRTVNPLKNNLYAPEIELTILEQPDREQLTQALEQGHYQVLHYAGHSNLGSRGGELYLVSSRTGLTETLSGDDLAGLLVNNGIQMAVFNSCRGAYGDPSDLGEDSPERNLTEALVKRGIPAVLAMAESIPDDVALTLTRLFYRNLKQGYPVDLSLSRARAGLITAYGSHQLYWALPILYQHPEFDGYLTATPTQNATGDSPLPKKSILGMQPLVAGAELKTRNSATVEQEPDSAHLEVKKSVPGVLGTQRYENQQNSPLSTLNSPSQVPTPTPPISTLGSSVITTPITRSAVVIHKPVKKSGLKKSLTVALCLLPVALSAGFFGWRHLQNSNAKPEELLPAVRTPISQGYVQIHPVNLEEAQTAKVMAIALNNFQAGEIWAGLKATEALLDQVALPQAEGALQAVPKYAIDNPEVNFLKGRLAWQFQQVGNKKYSVDDARRSWEMALKARPDSLKYRNALGFAYYAEGNFDRAYQVWTEVLSSIAPQSNQPTSSPSVRVGKHISTATAGLAMVMAKPIPNMTPQQQADRLTKAIQFREQAIASDSLSFEPSSLAKNWLWSKAAIRDWQSVQKLQKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY07</accession>
    <name>A0A2G4EY07_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000129">
        <property type="protein sequence ID" value="PHX54047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54047">
        <property type="protein sequence ID" value="PHX54047"/>
        <property type="gene ID" value="CP500_018180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14809" checksum="1798A344F5BBA699" modified="2018-01-31" version="1">MNDISNASATILDFLTLLEVEQAKKETSELFNAAIWQDLNQLNLKLNTINKPNKIALAILDWCEKYPEIYLALKTVSKVRCDIVGDDDIDIPLPAPDGDAEIIRNRDRIQKVIQENQQPPNQDLPSNPEPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY87</accession>
    <name>A0A2G4EY87_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54420">
        <property type="protein sequence ID" value="PHX54420"/>
        <property type="gene ID" value="CP500_016180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="32"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="425" mass="48507" checksum="25D3B9F03237E6F3" modified="2018-01-31" version="1">MSNPFNVGKPVPPELFVGRSYEIAAAFDQINNRTHFALWGGSGMGKTSFLELLASPQVWNKNGLDPSQAAIVLLNCENIIPFTPSGFWREVLSLMKDKLDSEPGLQGEIETLLGQGNITRNSLRQVLRQLGQKNKFLVLLVDDYDAALRPNEQYTEADMEQFVTECRSLAVNSEERKYLSMIVASLKRLNELGPQLRSNASPWYNHYLFQSLKPFNKTEIAQLLGGIPVKRELRDAIEEIAGGHPGFLQMAGFFIYIELRTGKRPDVQAFSTNFERDTQPFFHSIWARCSEQEQTLLMLMALSHLKGRLHNKKHFDLSGTDLIFTQRERELTKLEEAGVITRVAEGRVPYSFTSSIMERLVIQEIWNSDRVFLQERQKVFLNLMSHAQVKKFQTAINWLWNKKNEVPPTLEWLAKLAAAFNGLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY89</accession>
    <name>A0A2G4EY89_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54505">
        <property type="protein sequence ID" value="PHX54505"/>
        <property type="gene ID" value="CP500_015680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9806" checksum="2EDF1A0FFE2A4E2C" modified="2018-01-31" version="1">MKRINEINPLGEERPNPSDEIREQLRRSRLQREKDEGYQMLVELCNLGEYDMAQQFANRHFNWGYEIVDGIVMERIDCDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYC0</accession>
    <name>A0A2G4EYC0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_015630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000094">
        <property type="protein sequence ID" value="PHX54524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54524">
        <property type="protein sequence ID" value="PHX54524"/>
        <property type="gene ID" value="CP500_015630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="174"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="303"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="421" mass="47808" checksum="F079FC4AC23CF3B4" modified="2018-01-31" version="1">MQLVEKHIIKSTESRFAEIDQLAFKSKNLYNAANYVIRQNFIYGWGYANYNEMNRLMKSHEAYKALPAKVSQQILMVLDKNWKSFFEAVKAYKTDSSKFTGRPKLPKYKDKLKGRNLLVYTIQAISSKQLRNGIIKLSGTELSIKTQVNPDQICQVRLVPKCDSYVIEVIYDEPESTVSDDKFVAGIDLGLNNLVALTSNQPGFVPLLINGRPLKSINQFYNKRKAQLQSQLKGCRKTSPRIQRLTRCRHQKIDNYLHHASRTIVDVLVAQQIGMLVIGKNAQWKTEINLGKQTNQNFVSIPHARLIEMLEYKAFLVGIKVIVQEESFTSKANFLGLDPIPVYGKTETEPVFTGKRIKRGLYKTSTNQLINSDVNGAYNILRKAIPILRKAIPNAFSDGIVSCVVQPRRVNPLKVKQKGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYJ7</accession>
    <name>A0A2G4EYJ7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54548">
        <property type="protein sequence ID" value="PHX54548"/>
        <property type="gene ID" value="CP500_015450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="PTHR19353"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="2">
        <location>
            <begin position="49"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="367" mass="42532" checksum="381BF6F29CC5A755" modified="2018-01-31" version="1">MKIAVKKSDFVLTPYMKSNDLRATYQILNTVVPYLILWFLAVKAAAISLWLLPPIIVLMTLFSIRCFSLMHDCGHYSLFSSKKVNRIVGFMLGVINAIPQYPWSRDHAYHHKTNGDWERYRGVADFLSTEQFSKLNSSDQKLYELLRHPLMAFPGGFFYLAIQPRLALILGIYDFITHLFTCLKKEPRTGLSEIICAHKSKHWHTTTEFWDLLLNNICVISVWISLSHFLGAGFFLSFYSILLTFSAVIFIWVFFVQHIFEGSYAHNTKDWDYLLGAIEGSSYLELPTILKWFTADIGYHNIHHLSERIPNYNLEACHNENIHLLSNVKTLRIADMLHCSKFILWDSDSNSLVSIASIRQSILDFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYP8</accession>
    <name>A0A2G4EYP8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54598">
        <property type="protein sequence ID" value="PHX54598"/>
        <property type="gene ID" value="CP500_015275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="19325" checksum="AF3C1E1FE273EBA0" modified="2018-01-31" version="1">MVLTIEPLDSSRHHRELFCCGQDSLDNYIRKQASQDLKKKVAIVFVLVDSPNTDVIAYYTLSAYTIELADLNESFAKKLPRYPLLPATLLGRLAVDRTYQGQHLGELILIDALTKALLATAQVASLAVIAEALDEPAANFYQKYGFQKFKQNPMKLYLPMKSVEELCQNSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYS7</accession>
    <name>A0A2G4EYS7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54628">
        <property type="protein sequence ID" value="PHX54628"/>
        <property type="gene ID" value="CP500_014985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="86"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="157" mass="17891" checksum="2C9905D9236BDD92" modified="2018-01-31" version="1">MTALSQSKEPVIPSEADTQLSQLGSRILAAYFQTVRTSTQKIKIVESNGNEQVVDIPFVAFQLLFEILEQIAQGKAITLIPINAELTTQEAAQLLNVSRPYLTKLLKSGEIPFHQVGRHQRIRFEDVMKYKKWIDNERLKVLDELAFQAQELNMGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYU5</accession>
    <name>A0A2G4EYU5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA/pantothenate metabolism flavoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphopantothenoylcysteine synthetase/decarboxylase</fullName>
            <shortName evidence="3">PPCS-PPCDC</shortName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenoylcysteine decarboxylase</fullName>
                <shortName evidence="3">PPC decarboxylase</shortName>
                <shortName evidence="3">PPC-DC</shortName>
                <ecNumber evidence="3">4.1.1.36</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaC</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenate--cysteine ligase</fullName>
                <ecNumber evidence="3">6.3.2.5</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaB</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="3">Phosphopantothenoylcysteine synthetase</fullName>
                <shortName evidence="3">PPC synthetase</shortName>
                <shortName evidence="3">PPC-S</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">coaBC</name>
        <name evidence="7" type="ORF">CP500_016515</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:19397"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="6.3.2.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2</text>
            <dbReference type="Rhea" id="RHEA:16793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="4.1.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the C-terminal section; belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="3"/>
    <dbReference type="EC" id="6.3.2.5" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54357">
        <property type="protein sequence ID" value="PHX54357"/>
        <property type="gene ID" value="CP500_016515"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02225">
        <property type="entry name" value="CoaBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0288">FMN</keyword>
    <keyword evidence="3 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="5">
        <location>
            <begin position="5"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="DFP" evidence="6">
        <location>
            <begin position="188"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenoylcysteine decarboxylase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenate--cysteine ligase" evidence="3">
        <location>
            <begin position="193"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="307"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="399" mass="42795" checksum="E951BE716485C669" modified="2018-01-31" version="1">MKGRRVLIGVSGGIAAYKVCEVVSTLAKAGVEVRAILTDAAAEFVTPLTFATLCRLGAFTDKDFWEPNHGRPLHILLGEWAEVFVIAPLTANTLAKLAGGFADNLLTNTVLASKCPILLAPAMNTDMWEQPAVQRNWREVLTDGRYHAMSPGTGMLACDRVGAGRMAEPSEILAQIESLLYTKGDRDLAGKRVLISAGGTREYFDPVRFIGNPATGKMGIALARAALHRGAIVTLVHSITGEVPLLGVRSIALTSAEEMRQAMLECFTDADLTVMAAAVADVKPTEYHSQKLPKRSLPDALELTQVPDILAELGRLKQSHQKLIGFAAQTGDIVKPALEKLRVKKLDVIAANAIDKIGSGFGSDTNQAILINAEGKQVEIASCSKLAMAHRLFDFVMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ23</accession>
    <name>A0A2G4EZ23_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54774">
        <property type="protein sequence ID" value="PHX54774"/>
        <property type="gene ID" value="CP500_014220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="240" mass="27983" checksum="925A413F055DDAA6" modified="2018-01-31" version="1">MDDASLCQLIREALHDPKKAEALAFAIDQLPEVKRYLGQGWMPYYDEALPMTERDVKRNINKFSPMYRLNLEAVNYQNSSEAANVRASFIKWVMMILKRDCQDVKRRRDKQRAPVSTSETIGGEDSLTIEETLADDLTLSGIKLILERERRSLARQMKCYIEEDPEMRLRNCHPRNNSNLDCQLLSQKLLLEEPPLNPRQLAKELTTPEKPVPEQTVYTRWQKFCLPLLRKIAIELGYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ88</accession>
    <name>A0A2G4EZ88_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_013985</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54834">
        <property type="protein sequence ID" value="PHX54834"/>
        <property type="gene ID" value="CP500_013985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030660">
        <property type="entry name" value="ABC_branched_ATPase_LivF/BraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039137">
        <property type="entry name" value="ABC_branched_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="235" mass="25603" checksum="5E3FC3AFDEB50922" modified="2018-01-31" version="1">MLEIKDIHTYYGNIHALKGVSLTVSQGEVVTLIGSNGAGKTTTLRTIQGLLRPRQGTILFEGKPLESMSTEAIVRLGISQSPEGRLIFPRMTVQENLEMGAYLRNDTLGIKSDMEKALNLFPRLRERISQKGGTLSGGEQQMLAIARALMSRPRLLLLDEPSMGLAPMLVSQIFAIIRDINAQGTTILLVEQNARMALSVAHRGYVIQTGQVVVAGSASDLQSNETVRQAYLGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ96</accession>
    <name>A0A2G4EZ96_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATPase_AAA_core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54826">
        <property type="protein sequence ID" value="PHX54826"/>
        <property type="gene ID" value="CP500_013940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="26"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="379" mass="44033" checksum="153A9DBDC3131C05" modified="2018-01-31" version="1">MKIISLRLKNNFLGWDFDEIDFSSNLTLLVGVSGAGKTQILRAIIDLRRIANGKAINGFEWKIIFSTVNGTEFIWEGGFDTIETNELSFDEADKEKQDTQEKSSLVYERLTSNNQVLIERNKESILFNNIQMPKLSSHQSMIYILKEESIIKEAFDALNKISYRDHTRNGWHLRNSNQSLQSLKNKYNTLDSIVNSDEDIRTKLYLTYENEPNIFQKIRSRFIDIFQQIEDIKIEPMEIDELPKRLTENTAVISIKEKSVPKWIREDRMSSGMLRTIIHVSDIFLSNQGSVILIDEFENSLGINCIDILTDDMIHENKTLQFIATSHHPYIINNIPYEYWKIVTRQGGHIRICNSSDYHLGKSKQDAFIQLTKILEKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZB4</accession>
    <name>A0A2G4EZB4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54856">
        <property type="protein sequence ID" value="PHX54856"/>
        <property type="gene ID" value="CP500_013825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="59" mass="7016" checksum="7278EBA746995FE0" modified="2018-01-31" version="1">MPNSLFISLALRGLRLYSRGFNRRPHQPALETPYKKLQALQNINFTIYYYNYIGYSELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZB9</accession>
    <name>A0A2G4EZB9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000094">
        <property type="protein sequence ID" value="PHX54527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54527">
        <property type="protein sequence ID" value="PHX54527"/>
        <property type="gene ID" value="CP500_015645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021309">
        <property type="entry name" value="DUF2892"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11127">
        <property type="entry name" value="DUF2892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="22"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="19729" checksum="2FCD67439B6722D6" modified="2018-01-31" version="1">MTMTNDAQIQEIDAQTLKQLLDENAVTLVDVREAAEYATERIPGAKLHPLSQFNPDRVRPSEGKKLVLYCQSGNRSAKAARQCLDAGFNSVIHLRGGIPIWKNAGYPIEKSQNAPISLFRQVQIVAGSLVVMGTVLGVFVSPKFLLLSGFVGAGLVFAGVTNTCAMGMLLAKLPYNQQAGNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZE3</accession>
    <name>A0A2G4EZE3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="2">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">typA</name>
        <name evidence="2" type="synonym">bipA</name>
        <name evidence="4" type="ORF">CP500_013680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54881">
        <property type="protein sequence ID" value="PHX54881"/>
        <property type="gene ID" value="CP500_013680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="3"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="128"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="596" mass="66067" checksum="B93FCC0DF3A227CA" modified="2018-01-31" version="1">MSLPIRNVAIIAHVDHGKTTLVDALLRQSGVFREGEEVPDCVMDSNDIERERGITILSKNTAVRYKETLINIVDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVFVNKIDRDRADPHKAVDKVLDLFLELGADDDQCEFPYLFGSGLSGYAKKSLEDEGVDMKPLFEEILDHVPPPVGDPNKPLQLQVTTLDYSEYVGRIVIGRIHNGTIRVGQQAVLITESGALVKSKISKLMGFEGLKRIDIQESSAGNLVAVAGFADAYIGETITCPNDPQALPLIKVDEPTLQMTFSVNDSPFCGQEGTLVTSRQVRDRLMRELQTNVALRVEETESPDKFLVSGRGELHLGILIENMRREGYEFQVSQPQVIFREVGGRPCEPFECLVLDVPEEAVGGCIERLGQRKAEMQDMHVSSTGRTQIEFSVPARGLIGFRGEFMRLTRGAGIMNHSFLDYRPLGGEIVARRNGVLISFEEGTATTYSLKNAEDRGVFFITPGTKVYRGMIIGENNRDDDMELNICKSKQLTNHRASGGEELAQLQAPVDMSLERALEYIGQDELVEVTPKSIRLRKVSKKLVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZG5</accession>
    <name>A0A2G4EZG5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS domain-containing sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_015300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000090">
        <property type="protein sequence ID" value="PHX54577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54577">
        <property type="protein sequence ID" value="PHX54577"/>
        <property type="gene ID" value="CP500_015300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="35"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="177"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="459"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="732" mass="81117" checksum="085C716AEDA66612" modified="2018-01-31" version="1">MQTMPVKQKSQVLERDADGRTFVTHQLTEATVSESKEQFRRLVEHSPDTVAMVDCEMRYLSVSSRWQTACGLSGGDAIGRSHWELFPNLPEYWHQSVRAILAGVLESSEFVVRSTLGTQQTEFSSPEGIKWAFEPWKNGDGAIGGLIVTSSMAGKISSANCDRQLPPEPQTHQLETAAQITKIALHTCADLVFLTTSEGQICYANEATCRNLGYSQSELQQLKISDINPQLSLLDWQTHSSQVKEQNSLTFEAIYQTKEGRSLPVEVTANYFECDGEEYRCAIARDLSDRKVAESALLEAKEQLQAVLDAVPGLVSWVSSDLRYLGVNCHLAAAYQMPADIFLGQKVGFLETSSKFNDLVYKFFANPEKTISEEVTASVKGENKTYLIVAQKYQKDSKAVFVGLDITDREQALLALQESEERLRQQAAKQEQMLWVLQRTQTQLIQTEKMSSLGQLVAGVAHEINNPVSFISGNVSHARGYIQELLRVVELYQKNYPNAVPEIQDCIEELDLDFVKKDLVKLLNSMQLGSERIRDVVRSLRLFSRTDESEMKSVDIHEGLDSALLILQNRLQAKGGRTGISLVKEYGNLPRVHCYPGQLNQVFMHLLTNAIDALETGVKDSKKSGIIETNPHLSLRGLSGSMSNPEIRIRTTMISPSEVAIAISDNGPGMTEEVLGCIFDPLFTTKPPGTSTGLGLSISRHLVVEKHGGKLEYISEPGRGTEVVVKIAIGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZG9</accession>
    <name>A0A2G4EZG9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type 1 glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54905">
        <property type="protein sequence ID" value="PHX54905"/>
        <property type="gene ID" value="CP500_013535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="21486" checksum="BF4EE4D9AA96DF68" modified="2018-01-31" version="1">MIIVIDNYDSFTYNLVQYLGELGAELPVANEVQVYRNDQISLEAIRRFQPAAVVISPGPGRPEDAGISLELIKELGPTMPILGVCLGHQSIGQVFGGKIVSAPILMHGKTSQVQHSGVGVFRGVESPMIATRYHSLVIEKQSCPEVLEVTAWVEDGTIMGVRHREYPHIEGVQFHPESILTTSGKQLLRNFLERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZI5</accession>
    <name>A0A2G4EZI5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Type I restriction enzyme endonuclease subunit</fullName>
            <shortName evidence="10">R protein</shortName>
            <ecNumber evidence="10">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_013475</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Subunit R is required for both nuclease and ATPase activities, but not for modification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The type I restriction/modification system is composed of three polypeptides R, M and S.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the HsdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245952">
        <property type="entry name" value="Tbo703ORF13510P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54924">
        <property type="protein sequence ID" value="PHX54924"/>
        <property type="gene ID" value="CP500_013475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004473">
        <property type="entry name" value="Restrct_endonuc_typeI_HsdR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022625">
        <property type="entry name" value="TypeI_RM_Rsu_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12008">
        <property type="entry name" value="EcoR124_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00348">
        <property type="entry name" value="hsdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="250"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX54924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="952" mass="111281" checksum="4591910F77D5039F" modified="2018-01-31" version="1">MSQSEQELEQNLIDRLTGLGYEPVTIRNATDLAANLKTQLEKHNNTQLSPEEFKRVLNHLDKGNIFDRADRLRDKMELIRDDGTPTYLEFLNTEHWCQNQYQVTHQIAQQGSYKNRYDVTLLINGLPLVQIELKRRGLELKEAFNQINRYQRHSYGADFGLFQYVQIFVISNGVKTRYYANNRKQEYKQTFDWADSENNLITQLDDFATAFLEKCHLSKMICKYIVLHQSDKVLMVLRPYQYYAVEAIIERVKDTDKDGYIWHTTGSGKTLTSFKAAQILTALPKVHKVLFVVDRADLDYQTSKEFNYFSPDCVDTTASTKKLVNQMTGDSNLIVTTIQKLNNAISNPRHESVMEPLRNQRIVFIFDECHRSQFGETHKNIVKFFPNAQMFGFTGTPIFADNAASNAYGKRTTKDLFEECLHKYVITNAIADENVLKFSVEYWGKIKRKDGSLITEPKLDREFFENPDRISLIVDWIIENHNRKTHNKKFSAMLCVSNIDSLLTYYEIFKNKQKQGLHDLRVVTIFTPSINEDDEEANGLIGEPDFDLKTNSHSRDKLAEFINDYNALYQTQHSARDSKAFYTYYKDISKRMKDCDRENAQDRDRADILLVVNMFLTGFDVKKLNTLYVDKNLQYHGLIQAYSRTNRILGELKSQGNIACFRNLKENTDRAVALFSDANAKEEIFIEPYEYYIDKFNDGVQELRAIAPIPNDVNKLIDEDDQVEFVKAFRNLIRLLNVSKSFTEFDFAALNMDEQTFEDYKSKYLDIYDSTRSPKEEEDKSLIEEVDFELELIQRDEINVSYILKLLMELRQNTETTEEDYQKKKESILDLVGQEVQLRSKRDLIEKFIDEQMPIIKPEEAIETVFQNFWNQERTVAVRQFCLKENLKLEAVNQMIADYKFSGKEPLRDTVLNACNEKPKLLERKKVFDRVVSKLLHIINKFDDALGEFEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZT5</accession>
    <name>A0A2G4EZT5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55024">
        <property type="protein sequence ID" value="PHX55024"/>
        <property type="gene ID" value="CP500_012985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="620"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="278"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="641" mass="72675" checksum="C0CD73334E103F76" modified="2018-01-31" version="1">MFLVSSPKPIDPALQEFVQQIEKQSPAGISVLAGRQFRYCLEQISVEVTISEPRKFNILEEFILRAGMEMELTPTENELAQALGLDPIFVQNTANTLRSLETLAWTPDARIILTPQGKQFYLEGSVPQPPQTKQIYAISDPLQGNLFFLSSALEEVQIELPIFEDFITIENRCQEMPELGLEELQRIIQASGLGLHVPEDGKIITAANFTKETQAIWQSVAIFVIFDALEDAVKLQVRRGKQILHYASDLLDILQTEGKVSLQNLLYLSDETIAAEREELLNQRNKEVEDRIKKIEQQAIETVKELRETGEQVASKGSQEKDQVILLRDSQIRQSFLETLRKGNYQVLIYSPWVSKEVVDNEFIQLLQNLANRGVWILIGHGISRRQQDETRPIPPQVEQKLREIKTREGLSAVQVFWLGNSHAKEVVVDRKIHLCGSHNWLSYRGDKLPRGETVYKVTATDKVEEAYDFLAVRFKDYAGELWESAVQNRDANLAETSLCTWGALGMEEMALNQLQLANWLELYPVWLKVVCQGLRSKKISPDSAYLVTGISMVSQFSVDDSNIELLRSNLRQVIGAIAALDRRQALKLLNQNWSQFGRLSIADSALAKPDDFLFKYAVKEPDRPQTKSGKKASPKKNKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZX9</accession>
    <name>A0A2G4EZX9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55072">
        <property type="protein sequence ID" value="PHX55072"/>
        <property type="gene ID" value="CP500_012680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="26"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="51944" checksum="B9E3CCB8E3FBE8ED" modified="2018-01-31" version="1">MPRSLRLRLKCIPAVKSSLLRNGFPSQKILAEDLGIAQSTVSHFLNGKPVDYANFIEICRGLNQEWRDIADFELESQPDEVLPISAKIAIAQSNPNHELAVNLSEITNTKQSIIQPLPAAELPGGQVDLVSRLYIDRPPIESRCYETISQPGALIRIKAPRQMGKTSLMARILHHAEQQGSRTVALSFQLANRRIFANSDTFLQWFCASIGQELGMLEQLPKSWELADLIGSNQCCKAYFEQYLLSESSPPLTLGLDECDRLFESPEIADDFFGLLRALHEEAKRRDIWKKFRLIVVHSTEVYIPLDVNKSPFNVGLPIELPEFNEQQVQDLARRHGLNWIANEVAEFMGLVGGHPYLVRLGIYHIARQDVTLNQLVKSPATEAGIYSDHLRRHLWNLEKYSELMEAMREVASVSGPVRLRSELGFKLNSMGLVKLDGNHCIPRCRLYEGYFCDRLNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F020</accession>
    <name>A0A2G4F020_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3370 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55109">
        <property type="protein sequence ID" value="PHX55109"/>
        <property type="gene ID" value="CP500_012605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021801">
        <property type="entry name" value="DUF3370"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11850">
        <property type="entry name" value="DUF3370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="475" mass="52318" checksum="07FD2E3AD190883F" modified="2018-01-31" version="1">MFLPIFPLAQTIPTPPAQQLIIQPELPVPENELDLPPQPSSSPLKTVMQPQQVRVLPGQLDNIPVFNSNSPEVVQTEGILLSTFPQEAKQVPSAHLNFPFKGRFDIFAHHIAKAKNRSETRTLFQGIIVYNPNSEPVTLNVLQGASYLTQPDALFVDLPSYLENRLGTVFAGPGSRITSDVLRGYRQGILPAAIEIPGNQSRMLMNLPIPVGNVTPSSNGRSTLMRVSSSNFVYVASLAMFAPTTQAGVEQSPTLEQWENILTTKGLAGPRDLAPTAIGSNPEQKIYGRVAGVAEGSQWEAKITDSSRTDYLSIPKRGEEFSYALSTTDTGTFGTGQVQSAKMLARYPDTAYFAHGNYGIQYSLSFPLYNKSRESQSVSIKMQTPIKANTESGGLMFYDPPENRIFFRGTVRVMFSDDRGKTVTRYTHIVQRRGQQGEPLVNLNMRSGERRLVQVDFLYPPDATPPQVLTVRSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0J0</accession>
    <name>A0A2G4F0J0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-methionine-sulfoxide reductase catalytic subunit MsrP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55273">
        <property type="protein sequence ID" value="PHX55273"/>
        <property type="gene ID" value="CP500_011540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="1">
        <location>
            <begin position="112"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="327" mass="37208" checksum="0E72B667FB19FF37" modified="2018-01-31" version="1">MPLIRVPKAWEILDRQITSETVFHNRRRFMTNLIGAGVSASLLPLAGCKSNSGSNSALNRTSTQAYSGLIRNPAFAKVDRPITDEALATKYNNFYEYGGTKSIWEAAQALPTENWKVEVTGLVKNPRIYDIDELAKKFPIEERVYRFRCVEAWSMVVPWVGFPMKLLMADVEPTSQAKFVRFTSFYDPKITKGASVFSQFYPWPYTEGMRIEEMANDLAFFATGLYGRKLPKQNGAPLRQVIPWKYGFKGAKSIVKIEFVEKQPATFWNTIGPNEYGFEANVEPDKPHPRWSQASERVVGPGNSWSWETRETLPYNGYGEYVASLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0L6</accession>
    <name>A0A2G4F0L6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acyl-protein synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55302">
        <property type="protein sequence ID" value="PHX55302"/>
        <property type="gene ID" value="CP500_011580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013406">
        <property type="entry name" value="CHP02574_addiction_mod"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09720">
        <property type="entry name" value="Unstab_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8625" checksum="568BC957F878C010" modified="2018-01-31" version="1">MLSIERLMKEALSLPNALRAQLAERLVESLEFDIDGTVQKLWTAEAKQRRDEIRSGIVEPIPGKEALAQIRRIIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Q7</accession>
    <name>A0A2G4F0Q7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55341">
        <property type="protein sequence ID" value="PHX55341"/>
        <property type="gene ID" value="CP500_011390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="143"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="366" mass="40645" checksum="581E5A4C8D83363E" modified="2018-01-31" version="1">MLHGLFKIKENLTIQEKYLRGRWSIAILFATVAALEFTMPSEYLFGYLYTGPILIANSRLSRLGKLQITLVAAALTLLSLFVPYGEKIALSTVANRAIGVMALGVTGYLSDRNQQYQEAIAIAKAQLQSQQQLASIREDFVSTLSHDLKTPMLGAIETIKAFKQGKFGDLTSNQQKVLETMARSHKMTLQLVETLLDVYRNDTEGLKLQLSPVNLATLAEEVIATLIDLSAARRVYINMSYGESDFRRSLWVNGDAVQLQRVFANLLTNGINHSPRGGRVEVVMEFYSSYQVVKVLDSGLGITADELPRLFERFYQGNGDRQAKGSGLGLYLSRQIIEAHGGIIWAENKLPHGALFGFRLPAIPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0S0</accession>
    <name>A0A2G4F0S0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55345">
        <property type="protein sequence ID" value="PHX55345"/>
        <property type="gene ID" value="CP500_011305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="66"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="479" mass="54289" checksum="2A4FEADF0DF5CFFA" modified="2018-01-31" version="1">MPNSISQVQPPLEFIPPAYNPLIVQGCQQILPWWLRFKTNISDIQAENVETLAELFHQFQNQKVRFLLAFRHPNSNDPYCLGQLVWKLVPQVARQKGIPLKFPVHSHFIYDRGIPLWAGAGVGWLYSQLGGTPIVRGKIDRAGLRSARDLFANSQFPIAAAPEGATNGHNEIVSPLEPGIAQMGFWCVEDLRKADRTEKVVIVPIGIQYRYVNPPWGALEKLLTQLETDCGLAALDSSNIPNLNTENSNPDDHNHKFQYLRLIRLGSHLLVVMEEFYRRFYHQNILPKKADLSSLSITEITKNDLENADMTSRLPALLDVALQVAEQYFNLKPKGSLIDRCRRLEQAGWDYIYREDIKDIAALCPLERGLADRLAEEASLRMWHMRLVESFVSVTGKYVQEKLTAERLAETTLLLSDVLTRIKGGNPFGRTNLGKQRVQMTVGEPISVSDRWEGYQTSRRIAVAELTQDLQLALEGMIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0X2</accession>
    <name>A0A2G4F0X2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55403">
        <property type="protein sequence ID" value="PHX55403"/>
        <property type="gene ID" value="CP500_011050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="6"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="150" mass="17187" checksum="2278E4328E1D2CC9" modified="2018-01-31" version="1">MSVNRATRNLVRSRANFLCESCHSAEESSSTLFTIDHILPRSIGGNDELENLALACHRCNNNRYNFVTATDPETEKEVTLFNPRQQQWFEHFNWSADGLEIMGITPTGRGTCDRLDLNDRYHNEGAIIRARRLWIRAGWHPPSSDPCQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Y4</accession>
    <name>A0A2G4F0Y4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Light-independent protochlorophyllide reductase subunit N</fullName>
            <shortName evidence="1">DPOR subunit N</shortName>
            <shortName evidence="1">LI-POR subunit N</shortName>
            <ecNumber evidence="1">1.3.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">chlN</name>
        <name evidence="3" type="ORF">CP500_010935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 ADP + chlorophyllide a + oxidized 2[4Fe-4S]-[ferredoxin] + 2 phosphate = 2 ATP + 2 H2O + protochlorophyllide a + reduced 2[4Fe-4S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:28202"/>
            <dbReference type="Rhea" id="RHEA-COMP:10002"/>
            <dbReference type="Rhea" id="RHEA-COMP:10004"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83348"/>
            <dbReference type="ChEBI" id="CHEBI:83350"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="1.3.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; chlorophyll biosynthesis (light-independent).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Protochlorophyllide reductase is composed of three subunits; ChlL, ChlN and ChlB. Forms a heterotetramer of two ChlB and two ChlN subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the BchN/ChlN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.7.7" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55419">
        <property type="protein sequence ID" value="PHX55419"/>
        <property type="gene ID" value="CP500_010935"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00670"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016730">
        <property type="term" value="F:oxidoreductase activity, acting on iron-sulfur proteins as donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016636">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036068">
        <property type="term" value="P:light-independent chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019685">
        <property type="term" value="P:photosynthesis, dark reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00352">
        <property type="entry name" value="ChlN_BchN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000510">
        <property type="entry name" value="Nase/OxRdtase_comp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005970">
        <property type="entry name" value="Protochl_reductN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00148">
        <property type="entry name" value="Oxidored_nitro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000162">
        <property type="entry name" value="P_chlorophyll_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01279">
        <property type="entry name" value="DPOR_bchN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_nitro" evidence="2">
        <location>
            <begin position="22"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="466" mass="52420" checksum="93611014D157D1FD" modified="2018-01-31" version="1">MTTTEPEALNFECETGNYHTFCPISCVAWLYQKIEDSFFLVIGTKTCGYFLQNAMGVMIFAEPRYAMAELEEGDISAQLNDYDELKRLCLQIKRDRNPSVIVWIGTCTTEIIKMDLEGLAPKLEAEIGIPIVTARANGLDYAFTQGEDTVLAAMAAKCPEKAPVMESQKQERNAISQLLNFGKKKEEVAADESEYVKHTPLVLFGSLPDPVVTQLTLELKKQGIKVSGWLPSKRYTELPVLEEGYYVSGMNPFLSRTASTLMRRRKCKLIGAPFPIGPDGTRAWIEKICSVLGIEPKGLDEREAQIWAGLEDYLQIIRGKSVFFMGDNLLEISLARFLIRCGMTCPEIGIPYMDKRYQAAELALLEKTCHEMGVPTPRIVEKPDNYNQLQRIYEQNIDLVITGMAHANPLEARGINTKWSVEFTFAQIHGFGNARDILELVTRPLRRNNSLKDLGWGNLVKNEAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F108</accession>
    <name>A0A2G4F108_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2996 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55464">
        <property type="protein sequence ID" value="PHX55464"/>
        <property type="gene ID" value="CP500_010575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021374">
        <property type="entry name" value="DUF2996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36341">
        <property type="entry name" value="PTHR36341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11210">
        <property type="entry name" value="DUF2996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="17444" checksum="656B4B1187E0D21F" modified="2018-01-31" version="1">MSEETTNPTSPESPVPAEATKPPAKAKKEKAPAVEDKPFAEFIQQDYLPALQTALTKQGVKDLEVSLAKQKVPVSGMGSTGDCWQVIGRFQEGQRQFNLYFPQENIQTQRAFSCAENNTKTSTIEPFLIDERKITLDLMVFGVVQRLNAQKWLNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F196</accession>
    <name>A0A2G4F196_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Threonylcarbamoyl-AMP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55529">
        <property type="protein sequence ID" value="PHX55529"/>
        <property type="gene ID" value="CP500_010515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="221" mass="24349" checksum="FF4BF9D24A94CC32" modified="2018-01-31" version="1">MATIYEVHPFTPQKDRIEKIKKALKAGAVMLYPTDTVYAIGCDLNAKSAVERVRQIKQLSNDKPLTFLCSSLSNIAEYAAVSNEAYRIIKRLIPGPYTFLLPATKLVPKLVMNPKRKTTGIRVPDRPICFTLLEALGNPIISTSAHITADYEDEAPIATAKTENIGKAELFDCLSKLVDVIVDDGSDPGYQVSTILDLTESEPIIVRRGLGWEAAAAWEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1B4</accession>
    <name>A0A2G4F1B4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system HigB family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55543">
        <property type="protein sequence ID" value="PHX55543"/>
        <property type="gene ID" value="CP500_010175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018669">
        <property type="entry name" value="Toxin_HigB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09907">
        <property type="entry name" value="HigB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="9186" checksum="8E627E7CC661163C" modified="2018-01-31" version="1">MPKTIKVLPALFLLLELALEAPINKSSKPSLLISPFNIKGNRYRLIVDLIYDSQRIYIKYVLTHAEYDKDEWKNDPYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1P1</accession>
    <name>A0A2G4F1P1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55684">
        <property type="protein sequence ID" value="PHX55684"/>
        <property type="gene ID" value="CP500_009290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="6863" checksum="27C27E46DA78FB4D" modified="2018-01-31" version="1" fragment="single">SLLPPHSVYVPVGGAECGFLRGARGDLDLIVKQPSLTGLELKLTLMGNAVSLPTRRYIGKKFNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Q0</accession>
    <name>A0A2G4F1Q0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Folate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55682">
        <property type="protein sequence ID" value="PHX55682"/>
        <property type="gene ID" value="CP500_009675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GcvT_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="GCV_T" evidence="2">
        <location>
            <begin position="5"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="355" mass="38498" checksum="54EDB3C281A33CC4" modified="2018-01-31" version="1">MIQELHDIQTSSNAIFTELTTGETVAVSFGNDPAAITATKQGVALCDRTHWGRIQITDSDRLRFLHNQTTNNINKLQPGQGCDTVFVTSTARTIDLATAYATEDAVLLLVSPNRRRQLLELLDRYIFPMDRVELTDLTDTTVAFSLLGPESSKLLAQIGVSELENQPYATHKLIKPPPYQGGDEGGVRVAVGSGLASPGYTLIASASDAASLWHELVKAGAVPMGDRIWEQLRIEQGRPAADFELTDDYNPLEARLLHTITYDKGCYIGQETIARLNTYKGVKQQLWGVQLSGYVAPGTVVTIGEEKVGKLTSATETESGFFGLAYIRTKAGGEGLKVQVGEIAGEVVNLPFLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1S8</accession>
    <name>A0A2G4F1S8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_009390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peroxiredoxin family. Prx6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55699">
        <property type="protein sequence ID" value="PHX55699"/>
        <property type="gene ID" value="CP500_009390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03016">
        <property type="entry name" value="PRX_1cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045020">
        <property type="entry name" value="PRX_1cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="3"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="6">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="212" mass="23926" checksum="FEA256BAC3E9E970" modified="2018-01-31" version="1">MALRLGDTVPNFTQASSKGEINFYDWAGDSWVVLFSHPKDYTPVCTTELGAVARLKSEFEKRGVKTIALSVDDVDSHMGWIKDIEETQNVTLNYPILADGDRKVSDIYDMIHPNSLNNLTIRTVFVIDPEKKLRLSITYPASTGRNFNEILRVIDSLQLTDKYSVATPVDWKDGDDCVIVPSITDPQELAEKFPKGYTPIKPYLRMTPQPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1T5</accession>
    <name>A0A2G4F1T5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chloride channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_009430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55706">
        <property type="protein sequence ID" value="PHX55706"/>
        <property type="gene ID" value="CP500_009430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="Cl-channel_volt-gated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="SSF81340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="392"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="527" mass="55270" checksum="5D3ECCE4718CECB9" modified="2018-01-31" version="1">MRAIHPVDLLPPGKTAKIPHASLLSPVFNRLHPSPETLLLILSLVIGGVTGAGVVTFHYLIHLIHALMLEDFMGVISSSGSWTLACIPTLGGVVIGLMRWRFRDFGPNMSSLIAATRGLQELSPLKPITKMVAASVSLGTGASLGPEAPSVEIGANFGMLLAQVLQLSPERQRLLLGAGAAAGLSAGFNAPIAGVFFALEVVLGSTFATSSVSVVLLAAVVSALVAQICLGSQPAFAVPVYDVRSPLELPFYMGLGLLASIVSLVYTEAIQLAERCFQGKVPGFGWLGQLPRPIHPIIGGACVGLVALVLPQVLGVGYETVQAMLQDVEFSLPLLLELLFVKLAVTAISLGSGLVGGIFAPAMFLGASLGSAYGIFLTMVPALGDHVAGPPAYAMVGMAAVLAGSARAPLTAILLMFELTRDYRIVLPLMAAVGLSVWLVECVNRRSQAHSLNLQQMGVDVAVNEPLKAREQLQDWEDALGDRIVTELISCQLPIDEEQDGDEPVLAMANAHLPENVKPLSETKSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F225</accession>
    <name>A0A2G4F225_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55811">
        <property type="protein sequence ID" value="PHX55811"/>
        <property type="gene ID" value="CP500_008620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="90"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="398" mass="45035" checksum="3D0965D965D48E20" modified="2018-01-31" version="1">MATAIIDLDLYTLPPEITVEDRYSKALILIRMQGKPIGQALLPVVGGRIVGDELRETLRNAAGDNLWKIWLYDALAWDERGPVQATPIATVAVCTRDRPEDLGRCLDALMVMPDDGQEYLVIDNCPATDASSELVKKYPTVRYVREDVPGSSAARNCALREAKHEFLAFTDDDAVPDPNWLRSLLQNFSDPRVMCVTGLIMPLELETEAQEWFERYSPHGRGFYRRVFDGAYCNPLIVGPVGVSASMALRKSLIDFIGLFDEALGAGTPTVGGEDCELFARILRSGYRIVYDPRALSWHRHRRTWEELQKTLQGYGIGIYAFWTRIFVVNREFTVPLLAWEWLCCKQIPELIASVRKQPDSIPSDLLLAQLWGCISGPMAYFASRKRLQEIKEEVNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F245</accession>
    <name>A0A2G4F245_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aspartyl protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55819">
        <property type="protein sequence ID" value="PHX55819"/>
        <property type="gene ID" value="CP500_008660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="14138" checksum="6CF4F84511CA33BD" modified="2018-01-31" version="1">MIQGTFGDEDELFFEIELIADNGLELPVDALLDTGFSGWLAMDSQDLDGLDWTYIKQEKMRTAKGEFNFDLYAGKVRIEGQEFDIPVHVGTGVPEVLIGRQWLKNRRLVVDISAGVFDIGSELIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F254</accession>
    <name>A0A2G4F254_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55841">
        <property type="protein sequence ID" value="PHX55841"/>
        <property type="gene ID" value="CP500_008805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="218" mass="24760" checksum="73E40EC64F107BB4" modified="2018-01-31" version="1">MTAKTITDTALDRILAIKWEPDDSRVNSHIALLREYLRRAALWGKALDCTDEWPFFDVAAHICPLECADETKVKVLKNHFTETPFYVAGIIEKTCEWFLHWDRVKNLPKVSEFTLPEPYEPLIIMYERGGIFSMEHGFFDFAVGSFPRGKWQQYDEKMAAEWANPQIEALLSESAIAVNPNLVVHRGHSHGDHGHSHGDHGHSHGDHGHSHGGHGHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F283</accession>
    <name>A0A2G4F283_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RRXRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55856">
        <property type="protein sequence ID" value="PHX55856"/>
        <property type="gene ID" value="CP500_008460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025938">
        <property type="entry name" value="RRXRR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14239">
        <property type="entry name" value="RRXRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRXRR" evidence="2">
        <location>
            <begin position="4"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="339" mass="38646" checksum="1DD41DCF7C933D27" modified="2018-01-31" version="1">MQYVPVVDFDQRPLMPTTPARAERWIKSRKATPFFRKGVFCVRLNVQPSTRHTQPVAVGIDPGSKREGYTVKSKAHTYINQQFHAVDWVKDAEEASTNARRARRYRKTPYRPNRQNRKRGGIPPSTKARWQIKIRVVKVLAAIFPISHIGIEDVKATTKKGSKTWNTSFSPLEVGKQWCYSELEKIAPVTKFDGYHDTFLTRQELSLKKSKAKLSNDFKAHCVDSWVLAYLLVGGGSFPENTTVMECKQIRIYRRQLHVFNPGKDGNRRPYGGSMSQGLKRGGIVKHPKYGKCYVGGEDAKKSRISLHSLDTGKRLCQNAKPTDCKFLAYNSWRTVKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2N7</accession>
    <name>A0A2G4F2N7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NifU family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56020">
        <property type="protein sequence ID" value="PHX56020"/>
        <property type="gene ID" value="CP500_007655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU" evidence="1">
        <location>
            <begin position="11"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="8757" checksum="09680768F6945281" modified="2018-01-31" version="1">MTTLALTRDNVETILDEMRPYLISDGGNVQLVEIDGPVVHLRLQGACGSCPSSTMTLRMGIERRLREAIPEISEVEQVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2U5</accession>
    <name>A0A2G4F2U5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GGACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56069">
        <property type="protein sequence ID" value="PHX56069"/>
        <property type="gene ID" value="CP500_007505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="SSF110857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGACT" evidence="1">
        <location>
            <begin position="3"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="133" mass="15220" checksum="70C2E04BC873BDEB" modified="2018-01-31" version="1">MKVFVYGTLKPGECNYLRYCEGKVVDACPAIARGQLFALPAGYPAMIFEEGRVYGFLLCFADSTILADLDELEDYHPGRDRAQNEYQRESIEVFDLNFQPLGKAWAYFMLPDRVRSLGGIFIRDGTWVNRFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2X0</accession>
    <name>A0A2G4F2X0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56088">
        <property type="protein sequence ID" value="PHX56088"/>
        <property type="gene ID" value="CP500_007215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="388" mass="42114" checksum="C6512821310EF59B" modified="2018-01-31" version="1">MSQQANDLIKQGISQYQLREFEAALESWGHALTLYREVDDKRRSGAALGNMGVAYEALGDLARAIDCYEQHLVLAREIADRRGEANALGNLGNACCARSDFDGAINYQQQRLAIARDTADNRGEEEALGNLAASYDAKGDLRGAIECYDRQLAIGRARSDDRIERKALKSLKLAYKYLANYEQANYYRQQQLAIVRQLFLTEKNSDFVQLAEMVGLNPAEDFAGVDLSNFDLQYADFAGADLRDANLSGVDFTLADLSGALLSGAILIDATLCNANLRDSELNDANLSGADLRTKLPRANLQNANLTDANLSSAYLPNANLAGANLTNTDFRNSDMSGVNLSGATLNGADLSRADLKNIVVKDAKFAGCLGISEGLKIELTERGGIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F393</accession>
    <name>A0A2G4F393_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4065 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56205">
        <property type="protein sequence ID" value="PHX56205"/>
        <property type="gene ID" value="CP500_006765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025272">
        <property type="entry name" value="SocA_Panacea"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13274">
        <property type="entry name" value="DUF4065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4065" evidence="1">
        <location>
            <begin position="28"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="149" mass="16999" checksum="13831FD165599DFB" modified="2018-01-31" version="1">MLSCYDVAKYFLAQASEDAGDLISNLKLQKLVYYAQGFHLALYDEPLFPEAIEAWTHGPAVPDLYRYYKEYGAGAIPCPEDINFSIYDEETKSLLDEVYSVFGQFAAWKLGNMTHQEEPWKFAAQNGGKITHQSLKEYFKTQLNCEEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3H8</accession>
    <name>A0A2G4F3H8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bifunctional pantoate ligase/cytidylate kinase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">Pantothenate synthetase</fullName>
                <shortName evidence="15">PS</shortName>
                <ecNumber evidence="15">6.3.2.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">Pantoate--beta-alanine ligase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="15">Pantoate-activating enzyme</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Cytidylate kinase</fullName>
                <shortName evidence="15">CK</shortName>
                <ecNumber evidence="15">2.7.4.25</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">Cytidine monophosphate kinase</fullName>
                <shortName evidence="15">CMP kinase</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">panC/cmk</name>
        <name evidence="17" type="ORF">CP500_006165</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.</text>
    </comment>
    <comment type="function">
        <text evidence="15">Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 15">
            <text>(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 15">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">In the N-terminal section; belongs to the pantothenate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="15"/>
    <dbReference type="EC" id="2.7.4.25" evidence="15"/>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56312">
        <property type="protein sequence ID" value="PHX56312"/>
        <property type="gene ID" value="CP500_006165"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01349">
        <property type="entry name" value="PanCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024894">
        <property type="entry name" value="Pantoate_ligase/cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 15 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 15 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="14 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 15" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidylate_kin" evidence="16">
        <location>
            <begin position="319"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pantoate--beta-alanine ligase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cytidylate kinase" evidence="15">
        <location>
            <begin position="311"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="180"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="217"/>
            <end position="220"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX56312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="541" mass="59140" checksum="BA61E32B4BCC9FEC" modified="2018-01-31" version="1">MRLFTTIAALRCYLNSQKSAASHLQIGLVPTMGALHSGHLSLIQRARQENAIVVVSIFVNPLQFGPKEDFQDYPRNLEQDRLLCEQAGVDVIFAPSELEMFGKSGIDAGNSESPVLYGRMAIRPYTGEWPFAPTSLTQVVPPVAMTSVLCGKSRPGHFQGVALIVTKLLSLVQPTRAYFGQKDAQQVAIIRQLVVDFNMPVEIVACPIAREASGLAMSSRNQYLTQEQKQQASVLYRALQQGLKSFGSGRRTAEVILAVVKAEVAQESAIKLEYAELVDPNSLIPLSVVKTAGLLAVAAKIGSTRLIDNIIMRNRLPIVAIDGPAGSGKSTVTRKVAQVLGLSYLDTGAMYRAVTWLVMTTNTPISDEFAIAELVNSSYLEYNLDPASGLTLKINGEDVTEAIRSLEVTARVSEIAAVPAVREFLVEQQRRCGKIGGIVAEGRDIGTNVFPDAELKIFLTASVKERSRRRLLELKDGDRANTSLEQLERDIALRDEKDSTREVSPLRKAADAVEIETDGLTITEVIDRIVGLYKQRIVNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3L0</accession>
    <name>A0A2G4F3L0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56363">
        <property type="protein sequence ID" value="PHX56363"/>
        <property type="gene ID" value="CP500_005840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013787605" evidence="1">
        <location>
            <begin position="25"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="25846" checksum="6FAB9FE821527D25" modified="2018-01-31" version="1">MKVKILATVTTILASLWLAVPVKAQNADHVRQLLETKECEGCDLRNADLFKASLYRAKLKGADLSGANLYEANLIQADLTDANLAGANLVNADLYGADLDSANLRSANLSNAFLSRANMTMADLRGAKLFSANLAESYLLQANLSNTDLRRSLLFRVNLSRANLSGADLSFADVRDTNLQNAILSNTRLPKAQLSGTNLDAARDFRQADLERANLRGTNIGPVVCVTTRFPYCVLNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3L6</accession>
    <name>A0A2G4F3L6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA phosphorothioation system restriction enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56349">
        <property type="protein sequence ID" value="PHX56349"/>
        <property type="gene ID" value="CP500_005760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024012">
        <property type="entry name" value="Dnd_restrict_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04095">
        <property type="entry name" value="dnd_restrict_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="31"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="297"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="471" mass="53135" checksum="29B95EE4AC130936" modified="2018-01-31" version="1">MNHSTANNSQFGFPRMPPTLQLRQYQQEAVANWFANNGRGTLKMATGSGKTITALAIATELYQKINLQVLFIICPYCHLVNQWARESEKFGLQPILAFEEARSWQNKLVAGLYEVRSGDSLRDSCASRAFLTIITTNATLMGDSLRSQLRYLPEKTLIIGDEVHNLGAPRLGQSLPRNIGLRLALSATPERHFDEQGTEAILDYFGPVLQPELTLADAIRQKALVHYLYYPILVELTEAETRKYSYLTKKIGWALWGDEKGENNDALTPLLMQRARLIGAAANKLTALRELMSNRLDTAHTLFYCGDGAIEGTTRKNNNRQLIETAKLLGSELGYRVNTYTASTPLEEREKLRQQFESGKLQGLVAIRCLDEGVDIPAIRNAVILASSSNPRQFIQRRGRILRPHPGKERATLFDMIVLPPDLGRETIEVERNLLRKELRRFLEFADLADNAGEARVKLLQIQRRYGLLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Q0</accession>
    <name>A0A2G4F3Q0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56107">
        <property type="protein sequence ID" value="PHX56107"/>
        <property type="gene ID" value="CP500_007315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="89"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="288"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="365" mass="41928" checksum="EE24BA0C81BEBEB3" modified="2018-01-31" version="1">MNKKVSDKSTKAEILEAYKEAVEAKAALESQLKQVNNNLPANASPNQTVVPEKQIVEVNKPMTLVQNQQKMQSTIDNLILLQFGFGGAVSELSEKLTSEASKLEELQRTVGEEVQQLQELHSLEDVAEDTLDNLIQEYEESAKTFTEEISQQRETIEQDLLSRRQAWEKEQQLQEVAVQERNDGDQKTRDRDEELYYYDLNLQRNLDVEEYEQRQQTLYKEIEEFNQEQEKQWAEREKSISEREKLSAEVKAKVEAFPKELEANIKNGKDLGRNIGNYQAKIKSDLFAKDLEGQKQNYELQIQGMLQTIQNQESRIASLSKQLDSALKQVQDLAVKAIEGASNLNSFQAVKEIAIEQAKTQQKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3R0</accession>
    <name>A0A2G4F3R0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56117">
        <property type="protein sequence ID" value="PHX56117"/>
        <property type="gene ID" value="CP500_007370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="17930" checksum="E6D6457427607C21" modified="2018-01-31" version="1">MIYESQSRSSAIGASKIIHKSSVVNPRSRFVTEETVALLFNISPDEIYRIECCHNMVYVHGKGLSRFLSYADFPPIVEVNPPVLPDYLAWYKRWKGKQAPAFWTKFYTYNFKEAVSVDSLFQWGVLVGTVKSVMSAIALQQLRDVYAEEKDLMETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3R7</accession>
    <name>A0A2G4F3R7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56410">
        <property type="protein sequence ID" value="PHX56410"/>
        <property type="gene ID" value="CP500_005725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="204" mass="22433" checksum="356E328853030F66" modified="2018-01-31" version="1">MRYGKFRGLYIQFCNPCSEEYTEFLRRHGNLYAIGENCSIWPNTVFGDPAYVRIGNNVHFSSCTLIGHDGSIAMLDRAYNVKLDAVGKIDIRDNVFIGLNVIVLRNVTIGPNAIVAAGAVVTKDVAEGDIVAGVPARPIGRVEDLVKKLQAETQSLPWADLINSREGSFDPEIEPDLVKLRVTHFYGNTSTPTAAQFQQSPHPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3W1</accession>
    <name>A0A2G4F3W1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56474">
        <property type="protein sequence ID" value="PHX56474"/>
        <property type="gene ID" value="CP500_005125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="7979" checksum="21A63E0E82B1444B" modified="2018-01-31" version="1">MGRIRLRVREFAQEKGWNLTEVSKRTGIPYTTIITYANSPGMATVDYTALDKMARAFDIAIEDLVEILEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Z7</accession>
    <name>A0A2G4F3Z7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56441">
        <property type="protein sequence ID" value="PHX56441"/>
        <property type="gene ID" value="CP500_005410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="229" mass="26001" checksum="134F46C2E7186628" modified="2018-01-31" version="1">MLRLITDFDGPIMDVSDRYYRVYQQCLAETQGSDQQVRELPKAEFWDMKRAQVPETEIGLLSGLDATQAGEFAQKRRQTVHTFPYLKYDRLAPGGVETLEKVQRAGVDLVVMTMRRVRELDEAFNRCNLGRFFPEDRRYCLPNDYVKTGDVKDKPLLMAKALAELPQASDIWMVGDTEADIVAAKTHGVKVIGVLCGIRDRSQLESQQPDLIANNLGEAVEMIFDRSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Z8</accession>
    <name>A0A2G4F3Z8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56468">
        <property type="protein sequence ID" value="PHX56468"/>
        <property type="gene ID" value="CP500_005090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="8817" checksum="93A44D41A9B8C92F" modified="2018-01-31" version="1">MIVNLIIETTVGLISSFNLNDAVHLLVLKSHLGMTPILGQSYEIFTNFQKAWNHFVSSGQIAAFGIGLFVGWFFKGIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F412</accession>
    <name>A0A2G4F412_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56523">
        <property type="protein sequence ID" value="PHX56523"/>
        <property type="gene ID" value="CP500_005070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="13008" checksum="57C8C6E10445870B" modified="2018-01-31" version="1">MMSFSLSTTVVSPEGEQLYTFEYAALVTDTSITLVKVYVELGVIEPIGSMLHPREIARIPQIQRLRQDLGLNLVGAAMVLDMATEIAQLRSQLKAHQSHRSTVEDAFIGEVQRAGGAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F455</accession>
    <name>A0A2G4F455_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Photosystem II oxygen evolving complex protein PsbP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56526">
        <property type="protein sequence ID" value="PHX56526"/>
        <property type="gene ID" value="CP500_005085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="SSF55724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP" evidence="1">
        <location>
            <begin position="26"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="179" mass="19830" checksum="CD642D04053989B8" modified="2018-01-31" version="1">MIKRIVTMLLVVFSLTLTGCVSNVVGLKSYVDTGDGYQFLYPNGWLPIAVANGPDVVFRDLIQQTENVSVVISPVRGDKTLADLGTPSEVGYKLSKNAIAPPDSGREAELVNAESRESRSKNYYLLEYAVKLPNQQRHNLASVAVSRGKLFTLNISTTEERWPKVKEAFEKVVKSFSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F456</accession>
    <name>A0A2G4F456_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56267">
        <property type="protein sequence ID" value="PHX56267"/>
        <property type="gene ID" value="CP500_006270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="284"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="557"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_41" evidence="2">
        <location>
            <begin position="1208"/>
            <end position="1402"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1875" mass="214353" checksum="D0470C9CA32DBC69" modified="2018-01-31" version="1">MLSVIVFSKHRPLQLQSYLESLLYYSGLEERSIYVLYKETGGISYWELIKKYQKVNWIEETNFLSDLKNIFKYVKPYVLWGCDDVFYKSIFDLKICIKALSEKPELFGFSLRIGRNIQPYPELINQKDFLMWDWTRVELPHQSYEAGISDWAYPWEVSGSIYRKSDISEFLKLSNQPFNPNYLESNVADYCNRTKLSQKRKYLACFEQSKCLTLTINRVQETHKNAFWTTKKTDVDSLFKFFQSGYKLNWKKYHNCQNPSVHVGSDYFELEVKKLEGKSVPKISVIIPCYNQGRYLYEALESVVKQTYQNFEVIIVNDGSTDNTQEVAEEFIRIHPQYLIKLIAQANSGQPAIPRNRGISEAKGEYILPLDADDLIAPTMLEECLNLLETNTSVAIAYSDRQDFGESTQLICAGNYDFSKLIHANHISYCALYRKTVWENIGGYRTNVKGCEDWDFWIAAGIRGYFGYRIPKPLFKYRNNHTGLYQEVVRNYKNIFAQIIINNREAYKREEFSVSEILLHKISTQGLDVNLAKTSTVSLAYTAEKNDLSGVNTPLISVIIPCYNHATLLREAVESVVSQTYPNWECIIVNDGSSDDTSNFANYLIQLYPQKSLRLIDKPNTGPADSRNVGVQQSSGKFILFLDADDKLHPKFIEECVEILLAKPQVGFVYTDVQHFGANCDFVTHGDFDANRFLRDNQAPATSLFRREIYEQVGGLKKVMKLGCEDWEFWVSAYEKGWLGDRLPKPYLYYRQHGDGSSRTQKMAAERAKLDLMRATIINLHSQLYKPEEVRWSQQILQQHGNLISDELVQVNKPEQFLTSLSQYVGEYQKDQANEVSLANIRQSRQQLADYWLNLPVEQLPNAYASDLGKAHQILLHSNIKNESLTDTEQTLIDRLTAHLSQGIQTPKDINYLLAAALYRRADQLRLKYENAAIPNWFINDYLKFMFAAPMLFQEIGEADNYCRYVQGWVSYLHSNIFKNQNSQVWRDIAWFFTQSANFIPLYFNSENLKDIYTKRGDIIEYAMKNRGSAIDCIFPARLANRQKIRLGVLTKHFGAMTETFATLPAFEYLNREQFEIILYAVNLDGNKLEQYCQSRADRLVKLSNDLSSQVQHIRADDLDILLIATNITAVTHPISLLALHRLARVQTTCFNSPITTGMRHIDYYIAGKLMEPTPNGQEHYREQLATIDGPGCCFSYTLEPYTPSIKVTRNSIGISEEYVVFISSANLYKLVPELRETWAKILAAVPNSVLFLMPFGPSWTNHYPGGAFVNNMKAVFAKYGIDSERLRVLKSFPNRADVKEVLKLADVYLDSYPYAGTTSLVDPLEVGLPSVVRDGDTLRSRMGAAVIRSLSMPDLITNSEASYIQLAVTLGTNPQLRQRYRQEIQQKMQANPACFDSVAYSGAIAQLFQELFGKWQTDHQATSRILQDSIPKVADLGDRLLNTVKLYQTNSSNVSAISQLRQIRKEIADFWLNVPADNLETTYKGDSGKTYQILLASGFQHQPMMEDEQRFLQQLTQISKGLVHPQAINALLAAMLYFPPGTMRIPEARNRLPHWLISDYEQVFEPENAVNSASSSDLLVKYIQSPQFANQLLGCVNLYRIDSCDASVVLELRQLRRQLADFWLTIPPEKLATFYQGEVRKGYQAILGCGLQAELMTEAEQQFLQQLTEISTGLVHPQAINALLGAMLYFVPGKMRVPNANTRLPNWLIDDYDKVFESAFAQTEQTIVKQDYLPQFINQLTGAINLYKIDPMAEPVLVNLRQIRQQISDLWLSVSEEQLEVLYRSDFGKGYKAILASGFINEPLNESERAVFNSLVAELSKGFGMPKAVNYLLATMLFCRPGQLRVEDAKTCLPGWLLADYEQFVGGAVKVAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4B0</accession>
    <name>A0A2G4F4B0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56551">
        <property type="protein sequence ID" value="PHX56551"/>
        <property type="gene ID" value="CP500_004695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="13116" checksum="A4789866D9B42AE9" modified="2018-01-31" version="1">MERIEEYRQFIRQLLTSHAAPDPNSDSDVECQLVFDTEQDHYQILDVGWEGYKRIYNCFIHLDIKDGKIWIQRNMTEADLGQELVEMGVPKEDIILGLHPPYKRPYTGYGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4D2</accession>
    <name>A0A2G4F4D2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56606">
        <property type="protein sequence ID" value="PHX56606"/>
        <property type="gene ID" value="CP500_004530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8401" checksum="ECB06CFEDF8380CA" modified="2018-01-31" version="1">MIVIGYFLIASIVLLVWFHRFWNDTSTSKKDLISWVALLFLPLFWPLVLPFSLLQINSKKPEVEADQYDGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4H1</accession>
    <name>A0A2G4F4H1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_004380</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56649">
        <property type="protein sequence ID" value="PHX56649"/>
        <property type="gene ID" value="CP500_004380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PTHR12049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="408" mass="46632" checksum="B76546F8EB1E6477" modified="2018-01-31" version="1">MTFQQSDINDSNPELCNVICERIAATPQQRITFAEYMDLALYHPQYGYYNRDRPSIGKQGDFITSSHWGADFAEVLAEQFVEMWELLVSGALEEDRPFNFAIVEMGAGRGTFAQNVLQYLERQHPNLFKTLTYIIIEVSPTLESEQRQILGDFDRIKWCNWDEIVDDSIVGCFFSNELVDAFPVHQFILEKEELREIYITTETQKNQQKKINFIEVVGEVSTPKIAEYFELLGVDLSASVYGDGYRSEVNLAALDWMSTVAQKLQRGYLLTIDYGHPAHRYYNPRRREGTLQCYYRHRYHNNPYINVGRQDLTAHVNFTALERQGELCGLDVVGFTQQALFLMALGLGDRIAALSTSILDVATLLRRREELHRAIDPMGLGGFGVLVQSKGLREGEKGRTLKGLIVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4M0</accession>
    <name>A0A2G4F4M0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AbrB family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56661">
        <property type="protein sequence ID" value="PHX56661"/>
        <property type="gene ID" value="CP500_004365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="9771" checksum="926D9772A9BCCF32" modified="2018-01-31" version="1">MQQFPILLGQGGEITIPQLLQDALKVDRGDMLVLLQIGNLIVLAPKQPQAPKLIDRIATIMENENVGLNDLLSGLEAEREAIWREKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4T3</accession>
    <name>A0A2G4F4T3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56749">
        <property type="protein sequence ID" value="PHX56749"/>
        <property type="gene ID" value="CP500_003825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="141"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="313" mass="34691" checksum="BEB8C76B33D8FD01" modified="2018-01-31" version="1">MTVAVNKTPGLASRLVNGVLSIKPLADLAKHQAREMMIKRAEKIGVHWRQDAQALLARNWDAELLSVQNPDLVYPPYYLTSFHAYEKGNMSWEAATEVEVAARAVHAGIWPEAGAEGDAKLRESYHEIVNSQITKAPQNIVDLGCSVGMSTFAIQDIYPQAKIVGVDLSPYFLAVAQYRSQQKQAELSNQKSPTWVHAAAESTGLPGNAFDLVSIFLVCHELPQSATMEIFREARRLLRPGGHLAIMDMNPQSEIYAKMPPYILTLLKSTEPYLDQYFGLDIDRALLDSGFTKPTITCNTPRHRTVVAEAINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F500</accession>
    <name>A0A2G4F500_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="7">GPR</shortName>
            <ecNumber evidence="7">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="7">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proA</name>
        <name evidence="9" type="ORF">CP500_003560</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56818">
        <property type="protein sequence ID" value="PHX56818"/>
        <property type="gene ID" value="CP500_003560"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="17"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="320"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="435" mass="47105" checksum="B8BB2CDBB9A03A47" modified="2018-01-31" version="1">MNFSQVAATMSILEIAQKTRQAARKLAILSADAKNQAIEAIAQALEVAAPSIVAANAADCKAAEVDGIAKPLYDRLKLDESKLKSAIAGVRDVAKLPEAIGVVQIHRELDAGLILKRVTCPLGVLGIIFEARPEALIQIVSLAIKSGNGVILKGGREAVRSCEILTKVIRQALVETAVNPEVVQLLTTREETIELLKMDEYIDLIIPRGSNSFVRFVQENTRIPVLGHADGICHLYADKAADINKAVEIAVDAKTQYPAACNAIETMLVHSAIAPKFLPIVAQALQQKKVELRGDEKTRDILDIVAATETDWSTEYSDLILSIKIVDSVEEAINHINTYGSRHTDVIVTEDSEAAETFLNQVDAAGVYHNCSTRFADGFRYGFGAEVGISTQQMPPRGPVGLEGLVTYKYRVVGDGHIAASYVGNEAKEFTHRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F587</accession>
    <name>A0A2G4F587_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56920">
        <property type="protein sequence ID" value="PHX56920"/>
        <property type="gene ID" value="CP500_002775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030655">
        <property type="term" value="P:beta-lactam antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045155">
        <property type="entry name" value="Beta-lactam_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000871">
        <property type="entry name" value="Beta-lactam_class-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35333">
        <property type="entry name" value="PTHR35333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13354">
        <property type="entry name" value="Beta-lactamase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase2" evidence="1">
        <location>
            <begin position="159"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="312" mass="35062" checksum="696E203BA79B778A" modified="2018-01-31" version="1">MTFFRQDEQLETHGSSIIDAAKAEFTGLACDRIAITWIVYDPPVRVNTGGALSPEEYWKYQARGFSHRATERVYPASIVKLFYLVAVWEWAEKGMIKTSPELERAVRDMIVDSSNDATSLVVDVLTGTTSGPELPPGPFETWKQQRNIINRYFQSLNWLDLQDINLNQKTWCDGPYGREREFLGELMENRNMLTTNATAILLHSIIGGVAVSAKASQDMMSLMKRSLEPAELEADPENQVTGFLGGGLPQEAKLWSKAGLTSQVRHDAAYIEIPNLRPYLLVVFTEGKENSKNEEILPFVSRQVVEAMKALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F590</accession>
    <name>A0A2G4F590_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56973">
        <property type="protein sequence ID" value="PHX56973"/>
        <property type="gene ID" value="CP500_002485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="181" mass="19928" checksum="02E7B09EACAD5934" modified="2018-01-31" version="1">MQSNQNEQIAKATAENLELQDGGHSLARHGPDRSNIDLENRLTTGIAPNGVFSPTQASTRFNSYQDWLETRQAALNAIAKREGIDLSQPPPLGKQGSFNIILEHGKPIDDGFVGSGTKVKITDPVSGKQGKVYTNAQSVKGLTRTQTQLEWNSSTNRWEVKQHYPDARNWDQLTASYTAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5A3</accession>
    <name>A0A2G4F5A3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CopG family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56926">
        <property type="protein sequence ID" value="PHX56926"/>
        <property type="gene ID" value="CP500_002815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="46" mass="5617" checksum="5ECD13CDD75A2877" modified="2018-01-31" version="1">MKKRLDFRIEGFEFEILEQYCKDVGRTKTDVLRELIRTLKEKKKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5A7</accession>
    <name>A0A2G4F5A7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CopG family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56918">
        <property type="protein sequence ID" value="PHX56918"/>
        <property type="gene ID" value="CP500_002765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025528">
        <property type="entry name" value="BrnA_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14384">
        <property type="entry name" value="BrnA_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="83" mass="9576" checksum="958F6D094DAC0171" modified="2018-01-31" version="1">MKPEYDFSQGKRGAVIPQTGKTRITIYIDDDVLETFRERGDSAGKGYQTIMNEALREYLEKAKPPLDEETLRRVIQEELRAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5B9</accession>
    <name>A0A2G4F5B9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF790 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56901">
        <property type="protein sequence ID" value="PHX56901"/>
        <property type="gene ID" value="CP500_002675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008508">
        <property type="entry name" value="DUF790"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39640">
        <property type="entry name" value="PTHR39640"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05626">
        <property type="entry name" value="DUF790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019435">
        <property type="entry name" value="UCP019435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="405" mass="45899" checksum="A3E5F5BE28F386C7" modified="2018-01-31" version="1">MLPTDLLSHRQNGESIIPLRLKIDAKNLEAATEIINCFQESIGKTQGELDKHLQSLEGDSPDYRVKRGFAHLLRGGFSTFEVISPLEPSDLRQRVFALSARSTPSHHSTQLTLETLALELSQELNREVLTNEISTGLYADLNENKIFTQFDAPTAEALLHRYNLSQVQGIFYRASQVQLNAHRNDPGEYKLLFRYLKLFQLMTYIEGDAEIGFTLTIDGPTSLFKPSTRYGLALAKMLPALLHVTKWSMHSTLQTKDPFTGVLKTGKFTLNSECGLVSHYPPGKPYDSMLEAAFAERWSSTKTEWQLEREVDLIPIPGSVMIPDFRLVHPDGRVFLLEIVGYWRPEYLQKKFAQVHKSDCDNLILAISERLNLEKAGVKVKDVPAKVIWFKDKLLPKSVLEVLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5C8</accession>
    <name>A0A2G4F5C8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-6 DNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56911">
        <property type="protein sequence ID" value="PHX56911"/>
        <property type="gene ID" value="CP500_002725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008593">
        <property type="entry name" value="Dam_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05869">
        <property type="entry name" value="Dam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="192" mass="21708" checksum="CC5E3A21F3DEED3E" modified="2018-01-31" version="1">MTAGRQVISDKKDWGTPQKYVDAVKEVFGGVIHLDPCSSPFSIVGAVVECRLPEYDGLSEFWTFPTIYVNPPYGNDVKRGTKITDWFRKCEEANRVFQSEVIALVPVATNTGHWKKYVYGKATAICFLYDTRLRFLVDGKDEGKGAPMSCAMIYWGKNFPSFFDVFIKYGAVVNIENLRDVKIGCINKCDRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5E4</accession>
    <name>A0A2G4F5E4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56966">
        <property type="protein sequence ID" value="PHX56966"/>
        <property type="gene ID" value="CP500_002450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="486"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="565" mass="64584" checksum="47F369E6374BD84F" modified="2018-01-31" version="1">MSNLTNPPGGGEPPDIYRNVGEQIQAFFDYAEKNPDRAVPFFVNIWETQASLTTRALALQGLGVAAKHYRVKEAFADWDVLKDIAKEVKGKGEVSNDLTRWAAASALEAIGYSQQSLQHLEGGGFTEPLDRIRREIRDRKLIEINRIPRLNNRGETTAEYERHLEFWIYGPADELLNDRDRSLNYQDLVGDVISKLHGRGVYLGLISPNSIVQAAALRQAGLIFKESAQIEEYLYGLLEEFLHDSSHETSLRIHAAEIINTATDLNRRLKTLSKLLLEETELRNTAVRFSTPYKQELAKFESDAYTVLETLNFEYRLDKLEPKDLIISQIEQIITSSSQAIDVILARIETAIKAAENLARQYNKSSNLLVNFLKSKQDGYLSNIHNWIQTLRSQVAQLLDIHKKISENQSFLKQILSEIYPLDSQLYKKVSEIPNLAALDNQEYKNYSYHRCQSLKNILTQIQEGIKLCVNNQKLKMKQEKSLKEFIINCIVCFIFLLVSSFLFLLVAFIIMGGSNGTDIPLSLILTIVVSLILLIVCVSYHYYWTHIRPNKFEPILQQLSNWQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5H7</accession>
    <name>A0A2G4F5H7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX57006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57006">
        <property type="protein sequence ID" value="PHX57006"/>
        <property type="gene ID" value="CP500_002395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7386" checksum="9051690BB8381792" modified="2018-01-31" version="1">MTTHFISAEVHLHDTAEELHSAIEIELQKHGEPLRWAVTDVDVDRQKAVVEGYVLLESPVAPSPATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5P2</accession>
    <name>A0A2G4F5P2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57058">
        <property type="protein sequence ID" value="PHX57058"/>
        <property type="gene ID" value="CP500_001895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10614" checksum="8E756987737A4948" modified="2018-01-31" version="1">MQDFSLAAFIWAGRVHRPTRKLTLCGTGILPVHQKNARFQFSCLHLGGQGASPHKKIDSLWNRHLACSLPKISKQGDPIGSPYFISQKLQFVNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5U4</accession>
    <name>A0A2G4F5U4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57163">
        <property type="protein sequence ID" value="PHX57163"/>
        <property type="gene ID" value="CP500_001850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="43"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="208" mass="23127" checksum="CFA5799EF881BDC5" modified="2018-01-31" version="1">MTATIILPKNTDQKSEYESQPKFENTAEIQPESDTEKVISLEDFLVRPPDRMEWVDGNLVEKTGMTFKHGLAQVNLATSWKNYKNSSGHGGEVVTEVLCRTAKQGRRPDVAYITPELLQQQAGNFTTLSQSFPLIAEVASPDDSGEELFAKAQEYLASGCLEVWLLFPEARLIFVNAGNNWLLFNADEVVNTQRVLTGFSVAVNELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5W2</accession>
    <name>A0A2G4F5W2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 11">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplV</name>
        <name evidence="8" type="synonym">rpl22</name>
        <name evidence="12" type="ORF">CP500_001790</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8 11">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57152">
        <property type="protein sequence ID" value="PHX57152"/>
        <property type="gene ID" value="CP500_001790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_L22/L17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX57152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="119" mass="13436" checksum="4996CB1FEAAC17FB" modified="2018-01-31" version="1">MAIDTTSEIKAIARYIRSSPFKVRRVLDQIRGKSYQEALILLEFMPYRACEPIVKVLRSAVANAEHNAGLDKSKLVVSQAYADQGPVLKRFRPRAQGRAYQIRKPTCHITVIVAPLLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F603</accession>
    <name>A0A2G4F603_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BrnT family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56917">
        <property type="protein sequence ID" value="PHX56917"/>
        <property type="gene ID" value="CP500_002760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038573">
        <property type="entry name" value="BrnT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007460">
        <property type="entry name" value="BrnT_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04365">
        <property type="entry name" value="BrnT_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="92" mass="11144" checksum="8C5BD3C1EF624F73" modified="2018-01-31" version="1">MQFEWDEAKNLENIRKHEIDFADVPAMFDGEMLIELDDRFDYGEDRWFGIGFLGSGIAVVVWTERQNNVIRIISARRANRHEQKRFEQYLWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F644</accession>
    <name>A0A2G4F644_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF98 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57242">
        <property type="protein sequence ID" value="PHX57242"/>
        <property type="gene ID" value="CP500_000960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002800">
        <property type="entry name" value="Rv2949c-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01947">
        <property type="entry name" value="DUF98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="202" mass="22710" checksum="574F2815BA78E9AE" modified="2018-01-31" version="1">MTATLTPKNSLTWHALSPLWQGAEDAVQKGLPHTKLAPAWQILLLGDGSPTRHLQLLTTEPTEVDVIDMSLVGADADGAPEQIVVVPGPHLRRQVWLRTASGQRLAYATSWWEASHVDEYLQNKSLPIWASLARLRTELYRDVQGIYLGNSTALESAFEQPGPFWGRHYLFWHHGKPLTLIYEVFSPYLTKYLGPMQLDVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F677</accession>
    <name>A0A2G4F677_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57272">
        <property type="protein sequence ID" value="PHX57272"/>
        <property type="gene ID" value="CP500_001130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8806" checksum="0373BD90595FFEFC" modified="2018-01-31" version="1">MAYKSDHDFRTGLFKQVVKGMDDYQDRRFHDYLRDNYSDEKDSMTYQMLLDAAKAFMSRNYPDYSWNGQKWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F687</accession>
    <name>A0A2G4F687_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57235">
        <property type="protein sequence ID" value="PHX57235"/>
        <property type="gene ID" value="CP500_000920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="309" mass="35216" checksum="6FA165976949D754" modified="2018-01-31" version="1">MTRFIHDQFAKQYLKELLTPLGNVETSRDIAGEVRQLDVLFSPKAEPEIEATALGLLGQIAAKPAVFEPFRSPVQPGEIRSCLGKLFDLHAEFERIAARENTRIAEADLPQLWILSPTVSDPLLAGFRAISEPENWVNGVYFLGPSLKAAIVVIHQLPRTPETLWLRVLGKGNVQKQAVAELRELPSDNVFRLNALELLYNLRTILEVRQDIDREDRELIMELSPLYLQRLEDATQRGMQQGIQEGIQRAQRLMVENLLQVKFSEIDEELAQIIEPLIQLEPLDRTRLIMLLDRSQLLARFDPNNQTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6D2</accession>
    <name>A0A2G4F6D2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HEPN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57047">
        <property type="protein sequence ID" value="PHX57047"/>
        <property type="gene ID" value="CP500_002345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007842">
        <property type="entry name" value="HEPN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05168">
        <property type="entry name" value="HEPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN" evidence="1">
        <location>
            <begin position="19"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="15330" checksum="EDD8D387ABF4A05F" modified="2018-01-31" version="1">MKFDWSEYFNLAQELAGTSEEAKLRSAVSRAYYSVFCLARNYWRDIQQDPRLSRNKTYDINDHQYVAEEFINYRPKSQTMIEIGKDLTRLRKMRNKADYEDTIFNLQQEARTALMLAQNIISALNELTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6U1</accession>
    <name>A0A2G4F6U1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase C15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_001040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57257">
        <property type="protein sequence ID" value="PHX57257"/>
        <property type="gene ID" value="CP500_001040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PTHR23402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01470">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="SSF53182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="19239" checksum="6824C1C1A660E1BC" modified="2018-01-31" version="1">MPKFLLTSFDTWQPHQKSNSSDDLLARISQIKSWPYSLTFLRKLPVDAEQAAILAIAKINELQPDTIICGGMAESRQKLTVESCACCDNNILQTAVNLADLIADLPTIKISNDAGKFVCESLYYAVLKHLADSQLSTKCIFVHVPILTAENTDQILADFSLVIRRLARDETNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUB8</accession>
    <name>A0A2G4EUB8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribulokinase</fullName>
            <ecNumber evidence="3">2.7.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_023160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-ribulose 5-phosphate = ADP + D-ribulose 1,5-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19365"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoribulokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.19" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000270">
        <property type="protein sequence ID" value="PHX53131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53131">
        <property type="protein sequence ID" value="PHX53131"/>
        <property type="gene ID" value="CP500_023160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008974">
        <property type="term" value="F:phosphoribulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006082">
        <property type="entry name" value="PRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00567">
        <property type="entry name" value="PHOSPHORIBULOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="4">
        <location>
            <begin position="7"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="308" mass="34806" checksum="2D6101D830D3FFA8" modified="2018-01-31" version="1">MSDRPIILGIVGDSAAGKTTLTKGIAQVLGPENVTIICTDDYHRYDRTQRAEIGITALHPDCNYLDIMQQHLSLLRTGQAILKPIYNHTTGTFDAPEYIKPSKFVIVEGLLGYSTRAIRDSYDVKVYLAPPENLRTEWKVKRDIMKRGYTEEQVLAEMKKREGDSEDFIRPQRKFADVVVTFYLPEEDNEVNLSVRLVLRPTIPHPDFTEILSQSSDSFKPAIRLELDRDMGKPVDVLEVDSHATSEQVNELEKILCNEMPHLRGFCSTEGNSEIGKLVGTTGEILQSYPLALTQLIIAYHMIKAIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUH5</accession>
    <name>A0A2G4EUH5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1092 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000246">
        <property type="protein sequence ID" value="PHX53193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53193">
        <property type="protein sequence ID" value="PHX53193"/>
        <property type="gene ID" value="CP500_022775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009472">
        <property type="entry name" value="Tab2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34556">
        <property type="entry name" value="PTHR34556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06485">
        <property type="entry name" value="Tab2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="279" mass="31258" checksum="0DC2E19CD60A04EF" modified="2018-01-31" version="1">MQIWQADFYRRPLRDTAGKPLWELLICDSARSFEFSAFCSQSQANSNWLASQLQQQIQINKLPDRIQVFRPQSLSLIQAAGKVLGIKVEATRRTPALKLLLQSRAQEYPIMPNYTGEIYSAIALESPAPIPLPENLWGDRWRFASLPAGDIEDAFQSRPVPILEMPESLLPLNLAIASTVPIPGVVIDGGRQSMRLARWLQDVKPFALNYIAGTPDGLILEAGLADRFVVATFADDEVKEAAKIYEQRKQLSKGLHFLLVQPDDTGMTYTGFWLLNFNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUL1</accession>
    <name>A0A2G4EUL1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000238">
        <property type="protein sequence ID" value="PHX53221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53221">
        <property type="protein sequence ID" value="PHX53221"/>
        <property type="gene ID" value="CP500_022650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="32"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="19407" checksum="3D25A6759B6205C9" modified="2018-01-31" version="1">MTNQLTLEWTEAGVRQNQTIQNGQPSKNQGTVRIGRDPSKCDIILSHPTVSGLHIEIFFNQESQEFEVRNLRGESNPPLVDGKILVQGEAKLRCGSRLYLGELQLDVVWVSVTEVEIPHKVLVVEEKTLGYSSPTGPSRYGLQCPKCLRISPYAQLSAGCPWCGTSLAAAASVFLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUS4</accession>
    <name>A0A2G4EUS4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000223">
        <property type="protein sequence ID" value="PHX53281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53281">
        <property type="protein sequence ID" value="PHX53281"/>
        <property type="gene ID" value="CP500_022325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="206" mass="23326" checksum="81DFCDADA3510C42" modified="2018-01-31" version="1">MIQVSPKLVNFEEFVEWLPENSTVRYELHNGDIVEMAQPVGEHEEVTGFLTIKISALIDRLGLPYSIPNKVIVRPPEKDSGYFPDVLVLNRANLVNETLWQKQSILSLGASIPLAIEVVSTNWRDDYYLKYADYEEMGIPEYWIVDYAALGGRSFIGNPKQPTISVCNLVDGEYQVLKFRDNDRILSQTFPDLNLTANQIFGAGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUU1</accession>
    <name>A0A2G4EUU1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">33 kDa chaperonin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein 33 homolog</fullName>
            <shortName evidence="6">HSP33</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hslO</name>
        <name evidence="7" type="ORF">CP500_022765</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the HSP33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000245">
        <property type="protein sequence ID" value="PHX53200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53200">
        <property type="protein sequence ID" value="PHX53200"/>
        <property type="gene ID" value="CP500_022765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00498">
        <property type="entry name" value="Hsp33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.30.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00117">
        <property type="entry name" value="HslO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000397">
        <property type="entry name" value="Heat_shock_Hsp33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016154">
        <property type="entry name" value="Heat_shock_Hsp33_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016153">
        <property type="entry name" value="Heat_shock_Hsp33_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30111">
        <property type="entry name" value="PTHR30111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01430">
        <property type="entry name" value="HSP33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005261">
        <property type="entry name" value="Heat_shock_Hsp33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118352">
        <property type="entry name" value="SSF118352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64397">
        <property type="entry name" value="SSF64397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0862">Zinc</keyword>
    <feature type="disulfide bond" description="Redox-active" evidence="6">
        <location>
            <begin position="239"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="6">
        <location>
            <begin position="272"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="299" mass="31677" checksum="1462D87971971399" modified="2018-01-31" version="1">MADQLIRATAADGGIRAVGVITTRLTEEARARHKLSYVATAALGRTMSAGLLLASSMKRPESRVNIRIKGDGPLGGVLVDAGLDGTVRGYVDNPGVELPPNAKGKLDVGGAIGNGYLYVVRDVGYGYPYSSTVELVSGEIGEDLTHYLATSEQTPSALVLGVFVGANGVEASGGVLLQVLPKAATDEELVETLESRVAELSGFTPLLRSGKTLHEILEQLLGDMGLEIFQETQMVRFHCGCSFDRVLGALKMFGEAELQDMIEKDGGAEATCHFCNEVYKANRDKLAELIGDLRSDSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUX8</accession>
    <name>A0A2G4EUX8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000226">
        <property type="protein sequence ID" value="PHX53266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53266">
        <property type="protein sequence ID" value="PHX53266"/>
        <property type="gene ID" value="CP500_022390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003823">
        <property type="entry name" value="CP12_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012157">
        <property type="entry name" value="UCP_CBS_CP12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004697">
        <property type="entry name" value="UCP_CBS_CP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01093">
        <property type="entry name" value="CP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="76"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="205" mass="22981" checksum="7EC9748F4C01A132" modified="2018-01-31" version="1">MMMKAQDIMTTDVVTIRGSATVAEAVAMMNEMCLRALIVERRHEQDAYGIVTETDIVYKVAAYGVDPKKVRVFEIMTKPCITVNPDLGVEYVARLFANTRIRRAPVIKDKLVGIISVTDILTKSDFLEKPKSVLFEEEIEKAIADARTICSQKGATSRECAVAWDIVEEMQAEASHQRSMKLERTAFDEYCDENPDAAGARMYDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUZ0</accession>
    <name>A0A2G4EUZ0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000209">
        <property type="protein sequence ID" value="PHX53362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53362">
        <property type="protein sequence ID" value="PHX53362"/>
        <property type="gene ID" value="CP500_021900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="212" mass="23537" checksum="52E3BFC231581B4F" modified="2018-01-31" version="1">MSQTVWIARHGNRIDFVNPDWFLTAEHRYDPHLSEDGHVQAKQLAKRLKGERISHIFASPFLRTVQTANYAAEALDLPLKLEWGLCEWLNPEWMTEMPETMSVEALCQRFPRIDASYKGGIANYPETGEACLKRAGETAKRLAAEFPEDILLVGHGASVLGTAIGLAGGVETEINASLCCLVKVVQNEGEWSIALNGDTSHLTDTETLVRFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV71</accession>
    <name>A0A2G4EV71_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptide chain release factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53442">
        <property type="protein sequence ID" value="PHX53442"/>
        <property type="gene ID" value="CP500_021510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="15212" checksum="DD33F130B21B9CA0" modified="2018-01-31" version="1">MSDFLRGLKILPWQEILQIATLVNLTVLGIELFLAWSTKIPAISNALRLLYSSSLGILVPVAIAVGMGALAVYFLEYWQQQFLLNQTNLWLLVFCLFLGLFLKSLLLPPLFISLSQATLIGIAVGVFWKGRPYWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVD1</accession>
    <name>A0A2G4EVD1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">6-phosphogluconolactonase</fullName>
            <shortName evidence="7">6PGL</shortName>
            <ecNumber evidence="5 7">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pgl</name>
        <name evidence="9" type="ORF">CP500_021215</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5 7"/>
    <dbReference type="EMBL" id="NXIB02000190">
        <property type="protein sequence ID" value="PHX53489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53489">
        <property type="protein sequence ID" value="PHX53489"/>
        <property type="gene ID" value="CP500_021215"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="8">
        <location>
            <begin position="10"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="26012" checksum="2542517CEA82FC03" modified="2018-01-31" version="1">MQKVVEVLTNREELIARSLSIVRSKIQAAIAERGICTIALAGGSTPEPLYRAIATQDLPWDKIHVFWGDERYVPDDHPDSNQKMARLAWLDQVNIPASNIHPIPTGSADPATDALTYQTELQQFFQVSDGEFPAIDIILLGIGDDAHTASLFPHTAALEVRDALVTVGNKDGQPRITFTVPLINHARCVVFIVAGASKKPALAQIFAPAADDMTYPSRLIQPTGEVLWLLDAAAGEELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVE2</accession>
    <name>A0A2G4EVE2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000188">
        <property type="protein sequence ID" value="PHX53501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53501">
        <property type="protein sequence ID" value="PHX53501"/>
        <property type="gene ID" value="CP500_021185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7605" checksum="89546684C6CD0738" modified="2018-01-31" version="1">MLSVVEVLRNRFRKKEEPISLAASKLYFWAGGTPTPQENLTIVEQASCLFLRMTQDVRKSKKEKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVG1</accession>
    <name>A0A2G4EVG1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000184">
        <property type="protein sequence ID" value="PHX53519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53519">
        <property type="protein sequence ID" value="PHX53519"/>
        <property type="gene ID" value="CP500_021045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="2">
        <location>
            <begin position="12"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="213" mass="24390" checksum="ACDBFF8134964268" modified="2018-01-31" version="1">MASSSSVAVRELPLFPLPEVVLFPGRPLPLQIFEFRYRIMMNTILEGDRRFGVLMWDPDQNKVSAVGCCAEVIHCQRLPDDRLKIMTLGQQRFRVLDAVREKPYLVGLVEWIEDAPPQKDLRSLSRDVEQLLRDVVRLSSKLMDQAIDLPEDIPSLPTELSYWVASYLYGAATEQQILLELQDTAARLERETEILTSTRNHLAARTVLKDTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVK1</accession>
    <name>A0A2G4EVK1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000178">
        <property type="protein sequence ID" value="PHX53559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53559">
        <property type="protein sequence ID" value="PHX53559"/>
        <property type="gene ID" value="CP500_020880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039018">
        <property type="entry name" value="VapC20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42188">
        <property type="entry name" value="PTHR42188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="16126" checksum="21F20D235602FBEE" modified="2018-01-31" version="1">MKLIFADTFYWIALVNQRDDWHQQAVIITSNLKNVTIVTTDEILAEVLNFLSIYGIQMRRRTVGLIKDIMANPNIQVIEQARESFLQGLNLYENRLDKEYSLTDCVSMQVMKQLGITEVLTHDKHFTQEGFIILFTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVQ6</accession>
    <name>A0A2G4EVQ6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="8">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glycyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="8">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">glyQ</name>
        <name evidence="9" type="ORF">CP500_020540</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000172">
        <property type="protein sequence ID" value="PHX53615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53615">
        <property type="protein sequence ID" value="PHX53615"/>
        <property type="gene ID" value="CP500_020540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00733">
        <property type="entry name" value="GlyRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00254">
        <property type="entry name" value="Gly_tRNA_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002310">
        <property type="entry name" value="Gly-tRNA_ligase_asu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02091">
        <property type="entry name" value="tRNA-synt_2e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01044">
        <property type="entry name" value="TRNASYNTHGA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00388">
        <property type="entry name" value="glyQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="292" mass="33780" checksum="8A99DE30E04F5AC6" modified="2018-01-31" version="1">MNFQSVIATLNKFWSDRGCLIAQSYDTEKGAGTMNPHTFLRAIGPEPWSVAYVEPCRRPTDGRYGENPNRFQHYYQYQVLIKPSPPNIQEIYLDSLRALGIRPEDHDIRFVEDNWESPTLGAWGVGWEVWLDGMEITQFTYFQQCGSIDCRPVSIEITYGLERLAMYLQEVDAMTKIQWKDGITYGDVHLQGEIEQCTYNFEASNPELLFTLFGLYEQEAEQLTKQGLVLPSLDYVLKCSHTFNLLDARGVISVTERTRYITKIRNLARRVAQLYLEQREHLGFPLEKAVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVU0</accession>
    <name>A0A2G4EVU0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000166">
        <property type="protein sequence ID" value="PHX53655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53655">
        <property type="protein sequence ID" value="PHX53655"/>
        <property type="gene ID" value="CP500_020305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="349"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="455" mass="50039" checksum="71A58179B88E89D3" modified="2018-01-31" version="1">MTAIIPFIMYGWIPIVLYLFVRFPPQRAVIVSMIVAWQFLPQVSLSIPGLPPYSKMSAACYGVLLGTLVYDTARFTSFKPGWIDVPILICCLCPIASQITNGGSPLSPTLNQIVTWGLPYLLGRLYLNSLDGLRQLAIGIFAGGLAYIPFTMIEGVRGPILHQMVYGVNAFEDWGQARRMGGWRPVVFMQHGLMVGLWMMTAALIGFWLWQTGVLKKFQGRNMKTLAIILIIAFFLCRSTGAYSLFAMSLIVLFCAKLLKTSLPLLIIIGYIVFYLYLAASGQFSSAEVISFISQLFGEERAGSLGFRFQNEEILGDKARLRFLFGWGDSGGNRVYNEYGDDVSVTDSLWIIAFGVNGVVGLVSLFSALLIPAIAFCFKYPARTWSNPKVAPAAVLGITLTMYAFDSVLNAMTNPIFMLIAGGISGLVLKAPESLKAKKTSSPQTRRSLNPQKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVW8</accession>
    <name>A0A2G4EVW8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000163">
        <property type="protein sequence ID" value="PHX53681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53681">
        <property type="protein sequence ID" value="PHX53681"/>
        <property type="gene ID" value="CP500_020205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="10"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="20972" checksum="71ECF32B2C484C35" modified="2018-01-31" version="1">MTIATVHLTLEDFLQLPETKPASEYIDGEIIQKPMPKTKHSRLQLRTCNEINQVTESAKIAYAFPELRCTFDGRSIVPDIAVLLWEQIQFDESGEPVNDVLIAPYWAIEILSPQQSSNRVTKKIFHCLQNGCKLGLLIDPDDRSILAFLPNQQPQFCEGGDPVPVPEAIPLNLTAEQVFGWLKMNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW40</accession>
    <name>A0A2G4EW40_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Creatininase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_019680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the creatininase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53772">
        <property type="protein sequence ID" value="PHX53772"/>
        <property type="gene ID" value="CP500_019680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024087">
        <property type="entry name" value="Creatininase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003785">
        <property type="entry name" value="Creatininase/forma_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35005">
        <property type="entry name" value="PTHR35005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02633">
        <property type="entry name" value="Creatininase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102215">
        <property type="entry name" value="SSF102215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="248" mass="27024" checksum="A019B1E96427DA6C" modified="2018-01-31" version="1">MLLHLSTWPEVETYLESSRGIIIPIGSTEQHGPTGLIGTDAIAAEALARGVGEATNALIGPTINVGMALHHTGFPGTISLRPQTMILVIRDYITSLAKAGFEKYFFINGHGGNIATMKAAFSETYAHLSDLNLPNCDRIQCQIGNWFMCGSVYKLAKELYGNQEGGHATPSEVALTQYLYPEAIKQAPLSEEVASGHKIYGATDFRRRFPDGRMGSNPALATPEHGQQFYELAVKELTNNYLEFLSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW55</accession>
    <name>A0A2G4EW55_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000201">
        <property type="protein sequence ID" value="PHX53417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53417">
        <property type="protein sequence ID" value="PHX53417"/>
        <property type="gene ID" value="CP500_021615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="272" mass="31325" checksum="1327AE8D2CC597F5" modified="2018-01-31" version="1">MDRGFITILIGLYSFQDCIHFLASVRKFHQEPIVILIAGVPPYLYPLLKAFRNVILQPVPSNENPVLASRQAKLALYQASPFEKTIYMDSDICLLSPINDVFVYLDEFNFLVTEDVQPLIAKASNLLRVKQDILSTLQSVGLPLNENSIQYNGGFIAFTNSSKNQELFTCFKKYFEIVVAHQDVLFLRDQGAFAAAIASVKPKMKTLSPVYNYLDKWKELYRIDEPIKVMHCTYPYRPQYAKNVTRTLFTRIVDRTAQLFLPNQLNNPWRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWC9</accession>
    <name>A0A2G4EWC9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000147">
        <property type="protein sequence ID" value="PHX53862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53862">
        <property type="protein sequence ID" value="PHX53862"/>
        <property type="gene ID" value="CP500_019180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="457"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="486"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="549"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="887"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="914"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="938"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1044"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1074" mass="116002" checksum="5F57B8C9320F793C" modified="2018-01-31" version="1">MTADKTGFSISAIAIRRHIGTLMLTLAIVVVGIFYITQLPVDLLPSITYPRISVRLDAPGVSPEVAVDEITRPLEQGLSATEGVTQVFSRTREGQVSVDLFFRPGGDIDQALNDATASVNRIRNRLPDTVESPNLFKFDPSQQPVYEFALTSDSRQGVDLRVFADDELAREINVIPGVAAVDVSGGVQEEIQVNIDLNRLQSLGVNLNDVFNALRSRNLDISGGRLRQESKEPLTRTIGRFKTATEINNISFQISGSNPPKRVYLRDFAKVNDGTEEQRVKVFLNQKPAVKISILKQPDANTITVVDGVKNRLKEMQDSGLISADMKVVTTLDESRFIRNSLADVANAGVSGAVLAAIAVLFFLGSLRQTLIISLTIPLCTLAAIILMRLFGLSLNLFSLGGLALGIGQAIDTSVVILENIVVGLDSNPHLKKGRIKDRKERTIEESVMRSQEVESAMVASTAANLVSVLPFLLIGGFFSLLFSELILTISFAVAASLVVALTIVPMLTSRLMGMSYSSGISQFGPIKHFNRSFENATRAYGSMLSKVLGLRLIIIVVAFVILGGGTWVMAGQIPQEILPKVNTSQARLFALFPAGTNLETNQKVVAAADKLLLAQPETEYTLTTAGGLLFGNNTIENLLRGSSTITLKKGTNTIAFTERMTEELKKIDVPKGTRLRLVPEGIRGLVLTNSPVRGGEIDVIIQGPSEQVLQSAGRQILKELDEKVKLARFRPDGDAPQSEVQIRPDWERAALYGLSAQDIGETVQTAIEGTVPTQVQRGNRLVDVRVQFDRTSVKNIAQLGQIPLSGNNSIVRLSDVAKIAIGKAPGEIQRLNQRQVFLVVGNLNRGASLGDAVKQVDAVLSEMKLPPGVRIVPSSAAETNNQLQTALKLLGGLATFLVFVTMAVQYNSLVDPLVILLTVPLALAAGIFGLYVTKTAIGATVMIGAILLVGIVVNNGIIMVELANQIREDEKVDRTTAILRAAPQRLRPILMTTITTVLGLFPLALGIGEGSEFLQPLGVVVFSGLSLATLLTLFIIPCFYILLHDFFDMFAAKQKPQAVAIPVQKAGRKNANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWH2</accession>
    <name>A0A2G4EWH2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000145">
        <property type="protein sequence ID" value="PHX53883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53883">
        <property type="protein sequence ID" value="PHX53883"/>
        <property type="gene ID" value="CP500_019125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="879" mass="100726" checksum="BF00FCF2D1872583" modified="2018-01-31" version="1">MNQQVASEVNSTYQYQVGGYLPVNAPTYVKRRADEQLYEELQARKFCYVLSPPQTGKSSLLVQTAKRLQAEGTFIAGVNLKSISTPNISPQKWYGGIMYRIASSFNITHRFDALKWWNDRELLSPVQRLELFIEKVLLKSIQQNIVIFIDDIDSTKNLNFSAKDFFALIIDCYSKRVNRPEYARITFALIGVAVPLELIEHPNCHPFDIAEKINLDRLELLESLVLAKGLALKAFRPQKVLQEILDWSGGQPFLTQKLCSFVLEYGSFIGRNCEAQEIEKLTQIRIIKNWEDWDNPEHLITIRGGIFQTRCDLSQLLGLYQQILQAPDSEKAGETPGVAADLSPEQLELQKLGLVVKNSQNKLIVANRIYESVFNVFWVEQELGNLAPYKAALTAWLASECQDKSQLLTGSSLQAALDWAANKKLSPEHYSFLNPDRDLPKKAEVVFAPAEIITDSSIVNPGLLEMIPVSSDEQKLYNHIVSCVQTESPVKVIERFRQLFIDGMGYPDREIEATLYSIVSLKRSEQEFKYILHRCCYIPINRWQLNSQHKFAIGKLVALFKQTSPRFGMDFYIVKCLQHQINLFTKSEEFVTLERLVKAVEQGSQPEQQESNCPLGELICRYPYLYGYSLLSKGSIEEDQQTIKRLQFQRQKQFENDLSQYLNYLVDPRNTEIGIVQPAANPTLLKDAELHLAVREFAGKVKGDRSYKESARLFLSDAIPAPFYQSFKFDLYEYLISAVEPEYGGRQFNTRLFKYIKNTLPENDSAKLNNVLLARTCHQLFNFLVVENAQHPSHYVFYDLVYNLGPSRTMGLLLKLVLLSGKVKPELEKRFAILFNHYESKTSDEIMWFIKSLENLNVAFVMNFGNADLSLIKRNLILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWK7</accession>
    <name>A0A2G4EWK7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000149">
        <property type="protein sequence ID" value="PHX53846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53846">
        <property type="protein sequence ID" value="PHX53846"/>
        <property type="gene ID" value="CP500_019305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="326" mass="38223" checksum="1FD07370415F1313" modified="2018-01-31" version="1">MSLESTRRTVIHFVFLQIALLQQLWRAASRYTKMMLFYQRNNVIQLLKDGENLEKERPKILVGLAHITSIEEAQNKDVATKKIERLKHTIDGLLTSFAHCDLTIVVQTLPNRHITAYLPEYQINCIQVQEGPECDPMFVEFRLQEEFVNKVDEFDWFLFIEDDIILYDSFTIEKLEKFNRQSGYESAILYPNRYEMYEGTKRYIDLTIDTDLAWNKLSGVEIENVKFAEFTNPHAAFYCLSRKQMKQWIKSGRSWKNQVANVGPLESAATFCLLECFSIYKPHPSNLNYFEVRHYDNKYSQLYPEPESPYTLSAVDSSANKSKLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWT1</accession>
    <name>A0A2G4EWT1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54012">
        <property type="protein sequence ID" value="PHX54012"/>
        <property type="gene ID" value="CP500_018425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044213">
        <property type="entry name" value="At2g44920-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47200">
        <property type="entry name" value="PTHR47200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="18546" checksum="6E3FF70F79D6A0E7" modified="2018-01-31" version="1">MNSQMRQHIYTFLLSFVILAVFVTGAIAINPAPAFALNHDKEILIGTDFSGRALNDDSFNKANLRKSNFSNADLQGVSFFGANMEKANFEGANLTGATLDFAPMMKANLTNAILEGAFAYKTQLEGAIIDGADFTETLLRDDMVVKLCKVAKGTNPVTGRDTRETLFCDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWW5</accession>
    <name>A0A2G4EWW5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nuclease subunit of the excinuclease complex</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54024">
        <property type="protein sequence ID" value="PHX54024"/>
        <property type="gene ID" value="CP500_018295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="180" mass="20729" checksum="E9E45198E9724F93" modified="2018-01-31" version="1">MTSEIQTLASLEFFPYIDAEGKLPDFVQGKIGVCAIFDSEKVLQFVGYSRDIYLSLKQYLVRQHQHCYWLKVQMIDRPNRTILESIRESWIAENGSQPTGNGADAAKWNDPIDTKTVMTVEEITNYERIIIDEIAKDKLLKNVARRVENEILSELKARGVTEEIRFNPKLKTSGLLDLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWX0</accession>
    <name>A0A2G4EWX0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54021">
        <property type="protein sequence ID" value="PHX54021"/>
        <property type="gene ID" value="CP500_018385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000150">
        <property type="entry name" value="Cof"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00099">
        <property type="entry name" value="Cof-subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="290" mass="31894" checksum="E9281874CD6D53F2" modified="2018-01-31" version="1">MQNVMVSNRVSGGAEIKLLVVDIDGTIAGKSNDIREPVKQAILAAESRGVKVAVATGRMYRSALRFHRDIGSTLPLISYQGAWIQDPATDRVLRHLPLSKQRALELFEHFQEPHLRSLLSVNFYINDQLYVPEITAATRLYAERSGIEPIAIIDFRRDIPGEPTKVLALCENARVLDSLLSTMRERYTPAELYLTRSVSTFFEATHPLVNKGAAVKYIAEELLGLRAQNVMAIGDNFNDVEMIAYAGVGVAMGNAPSEVKAGANWVAPDVEEDGVVAAIEEFVLGDRSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWX9</accession>
    <name>A0A2G4EWX9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recR</name>
        <name evidence="9" type="ORF">CP500_018225</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RecR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000129">
        <property type="protein sequence ID" value="PHX54055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54055">
        <property type="protein sequence ID" value="PHX54055"/>
        <property type="gene ID" value="CP500_018225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01025">
        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00017">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023628">
        <property type="entry name" value="Rcmb_RecR_C4-type_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015967">
        <property type="entry name" value="Rcmb_RecR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034137">
        <property type="entry name" value="TOPRIM_RecR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02132">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01300">
        <property type="entry name" value="RECR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="79"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="7">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="197" mass="21954" checksum="FA5F0910B208E052" modified="2018-01-31" version="1">MYTRPLARLIEQLQRLPGIGPKSAQRLALHILKRPHEEVQILAQSLIDAKQQVGFCQVCFHLSAEPVCEICANPNRDNSTICVVSESRDVIALEKTREYRGKYHVVGGVISPMDGIGPEQLNIQPLVRRVSQQKIDEVIIAISPSVEGETTTLYVGRLLKPFTRVTRIAFGLPMGGDLEYADEVTLARALEGRRELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX24</accession>
    <name>A0A2G4EX24_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54028">
        <property type="protein sequence ID" value="PHX54028"/>
        <property type="gene ID" value="CP500_018315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="280" mass="29997" checksum="E3A86E2056A72AC9" modified="2018-01-31" version="1">MEADLILRQYAAGERIFREINLAGADLKGVDLSEANFTRANFQDANLKGANLTGANLREVKLSRVDLTETNLSEANLIGTDLSRANLCGANLTGANLRGSMAREVNMSKANLTEANLTEANFIQANLFAANLTEASMIRTNLMKANLSWSTLKAVNLTNAILSESLLERANLTKAILSGAILTGANLTGADLREVTMIGANLSEANLNNANLRVANMSWSTLRGANLSGANLYRAKLCWSNLSGAVLVETVLIDANLNRANLRDADLRRAIMPDGTTNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX42</accession>
    <name>A0A2G4EX42_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Carbamoyl-phosphate synthase large chain</fullName>
            <ecNumber evidence="13">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Carbamoyl-phosphate synthetase ammonia chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">carB</name>
        <name evidence="17" type="ORF">CP500_017900</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 4 Mg(2+) or Mn(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="13"/>
    <dbReference type="EMBL" id="NXIB02000124">
        <property type="protein sequence ID" value="PHX54115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54115">
        <property type="protein sequence ID" value="PHX54115"/>
        <property type="gene ID" value="CP500_017900"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01424">
        <property type="entry name" value="MGS_CPS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_A">
        <property type="entry name" value="CPSase_L_chain_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_B">
        <property type="entry name" value="CPSase_L_chain_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CarbamoylP_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033937">
        <property type="entry name" value="MGS_CPS_CarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="133"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="707"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="16">
        <location>
            <begin position="966"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carboxyphosphate synthetic domain" evidence="13">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric domain" evidence="13">
        <location>
            <begin position="966"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="858"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="870"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="872"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX54115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1099" mass="120367" checksum="426CDAB276311D4E" modified="2018-01-31" version="1">MPRRQDLKKILLIGSGPIVIGQACEFDYSGTQACKALREEGYEVVLVNSNPATIMTDPETADRIYIEPLTPAILEQIIAKERPQAILPTMGGQTALNLAVALAKNGVLEKYKVELIGAKLPAIEMAEDRLLFKEAMARIGVAVCPSGIANNLDEAKAIGHQIGSYPLIIRPAFTMGGTGGGISYNQEEFEEMAQGGVDASPVSQILIEQSLIGWKEYELEVMRDLADNVVIICSIENLDPMGVHTGDSITVAPAQTLTDKEYQRLRDASIKIIREIGVETGGSNIQFAVNPVNGDFIVIEMNPRVSRSSALASKATGFPIAKMAAKLAVGYTLDEISNDITKKTPACFEPTIDYVVTKIPRFAFEKFPGSEPTLTTQMKSVGEVMAIGRSFNESFQKALRGLETGRAGFGCDKPEKLPSLEQIRAGLRTPNPDRIFTVRHAMMMGMSVEEIFELTAIDPWFLDKMQELLETEKFLKRTQLKQLTKDTMFEVKQLGFSDQQIAYATKTSEDEVRTYRKQLGVIPIYKTVDTCAAEFEALTPYYYSTYEVGAAIWDLGDEEKKISPVGHSLAPESEVLPSTKRKVMILGGGPNRIGQGIEFDYCCCHASYSLGADGFETIMVNSNPETVSTDYDTSDRLYFEPLTKEDVLNIIEAENPEGVIIQFGGQTPLKLAIPLQKALENHPDVQTKIWGTSPDSIDSAEDRERFEKILRELNIQQAANGLARSFEDALIVAQRIGYPVVVRPSYVLGGRAMEIVYSDTELERYMTYAVLVEPEHPILIDKFLENAIEVDVDAIADTTGNVTIGGIMEHIEEAGIHSGDSACSIPYQTLPDEAVATIRRQTIELAKALKVIGLMNIQFAVQGKEVFILEANPRASRTVPFVSKAIGVPLAKIASRVMSGQTLEALGFTKEIVPVHVSVKEAVLPFAKFPGTDTLLGPEMRSTGEVMGIDTDFGKAFAKAQLGAGQVMPLSGTVLVSMRDRDKLAVVPVVKEFLELGFKVVATHGTRKVLREQGLDVDLVLKLHEGRPNLLDSIKNEKIQLIITTPSGEESRADGIFIRRTALTYKIPIITTIAGAKATAAGIRSLKSHPMEVKALQDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX68</accession>
    <name>A0A2G4EX68_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppnK</name>
        <name evidence="5" type="synonym">nadK</name>
        <name evidence="6" type="ORF">CP500_017755</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000122">
        <property type="protein sequence ID" value="PHX54129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54129">
        <property type="protein sequence ID" value="PHX54129"/>
        <property type="gene ID" value="CP500_017755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="67"/>
            <end position="68"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="149"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="192"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="306" mass="33600" checksum="2D04FC4AF8C3F99C" modified="2018-01-31" version="1">MQLKQVIIAHKARDPFSQRWAEQCARQLESRGCHVLMGPSGPKDNPYPVFLASSSSPIDLAVVLGGDGTALAAARNLAADGIPILAANIGGNLGFLTESFEDFKNTEEIWDRLSEDRYAVQKRMMLQAAIFQGNRTNLEPESDRFLALNEMCIKPASADRMPSCILEMEVDGEVVDQYQGDGLIVATPTGSTCYTASANGPIVHPGMDAIVVTPICPLSLSSRPVVLPPGSVVSIWPLADYDLTTKLWTDGILGTAIWPGQRVDVRMADCEAKFIILRENYSYYGTLREKLQWAGARIRYNNNHRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXB7</accession>
    <name>A0A2G4EXB7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide methionine sulfoxide reductase MsrB</fullName>
            <ecNumber evidence="3">1.8.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Peptide-methionine (R)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">msrB</name>
        <name evidence="5" type="ORF">CP500_018005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54090">
        <property type="protein sequence ID" value="PHX54090"/>
        <property type="gene ID" value="CP500_018005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01400">
        <property type="entry name" value="MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MsrB" evidence="4">
        <location>
            <begin position="9"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="132" mass="14882" checksum="2CE07330394C10C7" modified="2018-01-31" version="1">MTNKVQKTEAEWKEQLTPEQFKVARQKGTERAFSGEYHDNKQPGNYNCVCCGTPLFESATKYDSGTGWPSFYAPVNEENVKCESDNTLFMRRTEVLCAVCDAHLGHVFNDGPKPTGQRYCMNSAALNFVPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXC8</accession>
    <name>A0A2G4EXC8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000116">
        <property type="protein sequence ID" value="PHX54202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54202">
        <property type="protein sequence ID" value="PHX54202"/>
        <property type="gene ID" value="CP500_017475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="55" mass="6432" checksum="C40FF2BFED1E64B7" modified="2018-01-31" version="1">MDAQTIKERVAEIEIKRESLVRLLDRSDLGALRIDVSQAIEEIDDLLEEFKRTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXF9</accession>
    <name>A0A2G4EXF9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000119">
        <property type="protein sequence ID" value="PHX54168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54168">
        <property type="protein sequence ID" value="PHX54168"/>
        <property type="gene ID" value="CP500_017600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="237"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="431" mass="49377" checksum="A87768BD93FB01D4" modified="2018-01-31" version="1">MNHKKLKVLLIIEQCNPEWASVPLVGYNFFQKINNLVDATLVTHIRNKPALEKHPEYEKIFYLEECNLNKQYYKIVAKLTANGRVNWPLHNALSYPIYAEFNQQVYQKFQAKIVNGDYDIVHAITPMMPRYPCKVVNVCQQTPFILGPVNGGIPFPPGFQETAKQEFAQFNFLRAVGRALIPGYVETYKKADKILAGSTYTLNMLKDLFTIPDHRIDLFYENGISEEFLNQTNIPKKDASYINLLFVGRLVPYKCADIVIESIGKLDQAIQNKIRLKIVGDGQERNNLENRVKELHLDEIVSFAGWVNQQDTLDYYRKADIFCFPSIREFGGAVVMEAMACGLPCIVANNGGIGEYVNEETGFKIEPNSREYLTQELTSKIKLLVEDDQLRENMSAKAIEKAREFAWDKKAEKIVEIYQKMLDEKAIFAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXG7</accession>
    <name>A0A2G4EXG7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000149">
        <property type="protein sequence ID" value="PHX53847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53847">
        <property type="protein sequence ID" value="PHX53847"/>
        <property type="gene ID" value="CP500_019310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="447" mass="49666" checksum="1F14475B45C8C2C2" modified="2018-01-31" version="1">MSSEKKLAIKGAAWTIVSYGGSQIIRFGSNLILTRLLLPELFGLVGLAYVFIVGVHLFSDIGLGPSIIQNKRGEDPEFVNTAWTMQVIRSLFIWFCLMLITWPVANFYQEPRLLWLIPAISINTLIGGFNSTAIFSLNRKMSVKQVVIFEFGTQIISTTVMIVWALLNPSIWAILAGGLSGSLVELIWGHFLITGKSNRFAWDKSAVKEIFSYGKWIFLSTLLFFLCSQADRLVLAKIFDLTMLGIYGIAFTLSDMPRQVIIAIGGKVIFPSISMLADLPREELRAKILNNRNLILIPLAIGLAIFVSFGDQLILILYRKEYVAASWMLPILALGIWHTTLHNLMNSCLLAVGKSQYGALGNFATFLSISIGIPIGYHFMGNLGAVIAVAVGDIPTYLVISYGLWKEGLFCFWQDMKLTALFLSVLATILVCRYHFGGGLPIDRLFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXY6</accession>
    <name>A0A2G4EXY6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cation:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_016685</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54346">
        <property type="protein sequence ID" value="PHX54346"/>
        <property type="gene ID" value="CP500_016685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="291"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="43"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="467" mass="48222" checksum="CF2EDD569EFA514C" modified="2018-01-31" version="1">MFVNHTITALTSMIAHLVVPIPLLATLDPENSPIVLSGVLLSLVVIYLASKLGAEAARNFNFPPVLGELVAGVIVGVSALHLIVFPEGGLSASDSGIMSVLQSINHLSPVALTSIFESQSEVISVLAELGVIILLFEIGLESDIRQLKEVGVQAVVVACVGVAVPFAAGTAGLMMLFHTPAIPAIFAGAALTATSIGITSKVLSELGQLKSKEGQIIVGAAVIDDVLGIIVLAVVASLAKTGEIDVVNAIYLIVSATAFLLGSILLGGIFNKTFSAVVDTLKTRGNIVIPAFIFAFFMAFLGNAIHLEAILGAFAAGLVLDESDARNELDELVKPIADIIVPIFFVTVGARADLGVLNPAVPDNRAGLLIAAFLIVVAIIGKLVTGWVVFGQPGINRLAIGVGMIPRGEVGLVFAGIGSASGVLDKPLEVSIIIMVIITTFLAPPFLRIAFGDSVEPPATEESSKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY28</accession>
    <name>A0A2G4EY28_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UPF0060 membrane protein CP500_016390</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_016390</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UPF0060 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000104">
        <property type="protein sequence ID" value="PHX54388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54388">
        <property type="protein sequence ID" value="PHX54388"/>
        <property type="gene ID" value="CP500_016390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00010">
        <property type="entry name" value="UPF0060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003844">
        <property type="entry name" value="UPF0060"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36116">
        <property type="entry name" value="PTHR36116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02694">
        <property type="entry name" value="UPF0060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="5"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="107" mass="11832" checksum="5AA0D241C79BFD4B" modified="2018-01-31" version="1">MIQSLLLFVLAGVCEIGGGYLFWLWLREGKSPWLAVIGTVILAVYAVIPTLQPATFGRAYAAYGGVFIVLSIFWGWIVDRIAPDKYDLLGGWIALLGVLVIMYAPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY93</accession>
    <name>A0A2G4EY93_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system ParD family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54448">
        <property type="protein sequence ID" value="PHX54448"/>
        <property type="gene ID" value="CP500_016075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022789">
        <property type="entry name" value="ParD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03693">
        <property type="entry name" value="ParD_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="9962" checksum="15BBD6077F55E58D" modified="2018-01-31" version="1">MQIVLSPEVEALVQRQLTTGKYKSAIEVILAAIQLLEQQEDIYQGRLQELQRDALIGHLASQRGEVVDGVTAMAEIRANLRSRYTSLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYG4</accession>
    <name>A0A2G4EYG4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54572">
        <property type="protein sequence ID" value="PHX54572"/>
        <property type="gene ID" value="CP500_015420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="16186" checksum="25ECEF9BE311D1EE" modified="2018-01-31" version="1">MPRLDIYHNVVKAALIKDGWTITHDPFTIRFEDLTVYADLGAEKLIAAERSERKIAVEVKVFISPSPVTDLERAVGQYYLYSSFMARLEPDRTLYLAIPKRTYENFFQRPSIQEFVKERQFPLIVFNPDLEEIVLWKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYK5</accession>
    <name>A0A2G4EYK5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54558">
        <property type="protein sequence ID" value="PHX54558"/>
        <property type="gene ID" value="CP500_015505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="2">
        <location>
            <begin position="295"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="542" mass="60942" checksum="4CA4AB263659465D" modified="2018-01-31" version="1">MRKFTRPNPQGPKRDSRPFKSEGRGGDSSPSPRFERQPRPDTRGVAGPQKRSFGSSQEMPVRSVFKRNSDSDSKPELRRNNHFRDRDSSPQEFGGNNYRDRDSSPQPRTNNYRDRDSSPQPRTNNYRDRDSSPQPRTNNYRDRDSSPQPRTNNYRDRDSSPQPRTNNYRDRDSSPQPRTNNYRDRDGSPQPRSNNYRDRDGSPQEPRGSYLGNRDSRPQESRGSYFKDRDNSTQESRASHFGNRDSRPQESRGSHFSNRDSSPQESRSNYYKNRDSRVLETATSTVVQAEADTDMIYGRHAVQAALESDQVLNRIWVVPHLRYDPRFHSLLTEAKSNGCIIDEVDDLRLDYITRKSNHQGVAAQVSAYEYQDLSELIANAKLASESPVIVVAEGLNDPHNLGAIIRTAEALGTQGIVIPQRRAVGITSAVRKVASGALETLAVARVVNLSRALEELKEAGFWIYGTAADASQSVETINFSGPTVLVVGGEADGLSLLIQRGCDGLVSIPLRGKTSSLNVSVATGMALYEIYRQRGPKKFHVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYM3</accession>
    <name>A0A2G4EYM3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS110 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54621">
        <property type="protein sequence ID" value="PHX54621"/>
        <property type="gene ID" value="CP500_015195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="6"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="323" mass="35878" checksum="0C1EA122FF92F8F3" modified="2018-01-31" version="1">MTSTVLGIDISKRDFHVSLLKEGRATKPKKFTNNTQGFESLHNWLQQKNVVELHACMEATSIYGEALAEFLYGEGFQVSIVNPARIKGFAKSELLRTKTDSVDAALIARFCAAMKPSLWTPTAPEVKELQALLRRLESVTEMMTSEQNRLETATPTVAALTQSHLDYLKQQQQLIKKLISDHFDQYPHLKQQRELLTSIPGIGDLTASILLAEIGDVSDYDNARQLAAYAGLTPCERSSGTSVKGKTRLSCTGNVRLRKALYLPAVVAMRYNPLLKAMSDRLLGRGKVKMQVIGALMRKLVHLAFGILKSQKPFDPNYLTATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYR7</accession>
    <name>A0A2G4EYR7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54664">
        <property type="protein sequence ID" value="PHX54664"/>
        <property type="gene ID" value="CP500_014870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="330"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="376" mass="41893" checksum="1695C4537B408B83" modified="2018-01-31" version="1">MRYRRFGKTNLNLSVFSLGTMRYLASEETACQTVQQAVSQGINHLETAAGYGCSEEYLGAAISAGLALDRSRLHITTKICPTDDAAAMERSIDQSLKRLNLDYLDCLAIHGLNTWEHLAWVQADTGCMATVQKAVADGRIRHVGFSTHGPLELILAAINTDLFEFVNLHYYYFFQRNAPAIELASQKDLGVFIISPADKGGQLYTPPETLKELCLPFSPLELNYRFLLSDTRIGTLSVGAANPMELEEPLKYGDRDFPLTPSEIAAFDRLESVMVSNLGIDKCSQCYACLPCPENINIPEILRLRNLAVGCDMTDFGKYRYAMFENAGHWFPGNKGNRCTDCGECLPRCPEKLDIPALLEDTHQRLSGKSGRRLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYT4</accession>
    <name>A0A2G4EYT4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">recJ</name>
        <name evidence="9" type="ORF">CP500_014785</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54682">
        <property type="protein sequence ID" value="PHX54682"/>
        <property type="gene ID" value="CP500_014785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004610">
        <property type="entry name" value="RecJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041122">
        <property type="entry name" value="RecJ_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17768">
        <property type="entry name" value="RecJ_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00644">
        <property type="entry name" value="recJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="6">
        <location>
            <begin position="95"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="7">
        <location>
            <begin position="350"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="RecJ_OB" evidence="8">
        <location>
            <begin position="499"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="697" mass="76595" checksum="AA06F6BDD544E652" modified="2018-01-31" version="1">MLELPPSKSSHLHRLPNQRWQIYSPQPQQAERLAAEIGLSPLLAQVLINRGMDTLTEVQGFVEPESLVLPQPMDEFPDLAVSVKLLREAISRGQKIAICGDYDADGMTSTALLLRALRVLGANVDYAIPSRMREGYGINDRIVEEFHSEGVALILTVDNGIAAFGPVQRARELGVKVIITDHHDLPPQLPPADAILNPKLIAESSPYRGLAGVGVAYVLAISLAQSLHKVGGLVNPLLELFTLGTIADLAPLTGVNRRWVKRGLRLLPHSQLAGVQALIQVAGVQQGSSETPLIPNFKTQVQNSLKPEDIGFRLGPRINAVGRLADPQIVIELLTTDDRDLALIRAMECEQINQRRQELCLEIEQEAIAWCEEKSPNLQQERVLVVVQPGWHHGVIGIVASRLVERYGVPVFIGTFEDEADEDEPNKSKIVRGSARGIPEFNVFEGLNFCADLLTKFGGHKAAGGFSMPAENLEKFGSQLSVFANQCLEPEHLKPLVSVDVQADLSEINLDLYRQIDALEPCGMENKAPVFWTANVSITEQKIVGKGNHVKLTASQTGKIPASLGGIAWRWGEYFPLPRLVDIAYRLRENTFNGKTSVQLELLGVRLPVSLGNSDLRVSPKSKAEFDYYDRTYSCSLSRSGDLQELRIRNSQGQILAIQPGQKTGLLGNSRENAQEVDVSRPFFENLIQTASRALGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYY0</accession>
    <name>A0A2G4EYY0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_014430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54735">
        <property type="protein sequence ID" value="PHX54735"/>
        <property type="gene ID" value="CP500_014430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="151" mass="17029" checksum="0F669B1C4EDC06CB" modified="2018-01-31" version="1">MRRLWQIGQTVLGLIFRHPITGTGIIPILPDGRIVLIRRRDNGCWALPGGMVDWGENITTTVRRELAEETGLELVKIRRLVGVYSEPDRDPRLHSICIVMAADVEGTIQIQDTLEISEVKAFLPTSLPEGEFSHDSEKHLQDYFQGLTIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYY9</accession>
    <name>A0A2G4EYY9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54745">
        <property type="protein sequence ID" value="PHX54745"/>
        <property type="gene ID" value="CP500_014485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7395" checksum="EABB7E3A329B21FE" modified="2018-01-31" version="1">MRTQLWIQHSPLAGYASNIIRFSTAGSLSNVSINGRSTAIVASMLAIATALITKKLDIAQPQKHCTINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ03</accession>
    <name>A0A2G4EZ03_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Diflavin flavoprotein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_014450</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Mediates electron transfer from NADH to oxygen, reducing it to water. This modular protein has 3 redox cofactors, in other organisms the same activity requires 2 or 3 proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the flavodoxin reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54739">
        <property type="protein sequence ID" value="PHX54739"/>
        <property type="gene ID" value="CP500_014450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="6">
        <location>
            <begin position="265"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="575" mass="63541" checksum="762158DEF5D042E9" modified="2018-01-31" version="1">MVALTERVQRRLTVEKVEIATDTTTIRCLDWDRDRFDIEFGLKNGTTYNSFIIRGEKTALVDTSHEKFRQQYMDTLTGEIDPKQIDYIIISHTEPDHSGLVKDVLAIAPQAIVVGAKVAIQFLENLIHQPFERLVVKNGDKLDLGNGHIIEFVSAPNLHWPDTIFSYDSKTQVLFTCDAFGMHYCTDSTYDDDLAAVEEDYHFYYECLMAPNARSVLSAMKRMADLGEIGTVATGHGPLLRYNVVELTGRYKKWSQEQTKAETTVAVFYTSDYGFSDRLSQAIAHGITKTGVAVEMMDLKIADLQEVRELVGTAAGIMICSPPSTGAAGVNAEAAINTILVAANNKQSFGLCESGGGDDSSIYPLRNKFKELGLKEIFPNILIKETPTEAIYQLCDEAGTDLGQWLTRDKTVKQMKALDSDLDKALGRISGGLYIITAQKGEVSGAMLASWVTQASFKPLGLTIAVAKDRAIESMMHAGDKFVLNVLEEGNYQTLMKHFLKRFAPGADRFAGVKTQLATNGSPILTDSLAYMECEVVSRMELSDHHIVYAIVDNGRVSNPDALPAVHHRKVGNHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ08</accession>
    <name>A0A2G4EZ08_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fimbrial assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54752">
        <property type="protein sequence ID" value="PHX54752"/>
        <property type="gene ID" value="CP500_014295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007813">
        <property type="entry name" value="PilN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05137">
        <property type="entry name" value="PilN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="309" mass="33103" checksum="FF523060886A60D5" modified="2018-01-31" version="1">MYSLDINFLRDRPEYKQDEPAKVSTKKGSGSVKDQLPLIGALIFALGINVVVMGAWWWSTNENNKLTTVQTTLDQEVTKLNTEASAVKAINTETDKVTAEYQALAGVFDQIKPWSAMLQDLSSRTPAGVKIAKIEQIDPSPSPIAAPPPPPPPTPAATASPSPGASPSPPASPTPAAVPTPVAPPQAAKIVISGVASTFDQVNDFMLLVQRSPFFLNTDTRLVAATLKDNPAQVQVRNQSALGTVEIPKLRQVVEYKIETSLSPTVASELLPELRSKQADGLAIRIETLQEKGVLETPKGEQKGEVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ12</accession>
    <name>A0A2G4EZ12_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54749">
        <property type="protein sequence ID" value="PHX54749"/>
        <property type="gene ID" value="CP500_014420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="7194" checksum="E78A1DC54BD1F082" modified="2018-01-31" version="1">MAKRRNLKKEKAQRNQAYARKFRKRRNQDMFSNKRRRFDGGNGGGMGAMTGGGRDKDMAAAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ47</accession>
    <name>A0A2G4EZ47_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54779">
        <property type="protein sequence ID" value="PHX54779"/>
        <property type="gene ID" value="CP500_014250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="48" mass="5566" checksum="4BFD976C47A49C15" modified="2018-01-31" version="1">MNYHERITIEPGKRSGKPCIRGMRITVYDVLSYLASGMTYQEILDDFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ58</accession>
    <name>A0A2G4EZ58_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245730">
        <property type="entry name" value="Tbo703ORF15900P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54467">
        <property type="protein sequence ID" value="PHX54467"/>
        <property type="gene ID" value="CP500_015895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="343" mass="38828" checksum="9B9EBD007F434736" modified="2018-01-31" version="1">MESTTFYKVASDAMKDYIEIYLSLSKQSDGFSNIQNLDLTVRNSRLVVIHGLSLELDPDTSTSEEIKREAERMLAVTLDTESAITAGVYERMRLFAASLVDELFEETDELQLLSSEYLSAHPGLLPFFQQLAGLRSKSELKREVGNASDNGISKVVAEKILDRITRNLRTRTFSKERLLQAVEPTLEGIVRDLVGKVLLENIVADALSDLQVPFMRESEYKNLRGVIYDFRADFVIPDAQNPVAFIEVRKSSTRHASLYAKDKMFSAINWKGRNKKLLGILVVEGPWTRETLRVMANVFDYVTPLTRVSQVAEAVRAYIDGDETKLKWLVNFSIEEANRSKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZF7</accession>
    <name>A0A2G4EZF7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54567">
        <property type="protein sequence ID" value="PHX54567"/>
        <property type="gene ID" value="CP500_015390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="342" mass="38928" checksum="6F22ECF1828375DC" modified="2018-01-31" version="1">MQLKSAVQWIPHPDGHWILRNPEDITCLQIDDFDKQVILLLNQQPLTNILAEYDLDVEDVQNLLKDLAQAGMLEGTKPPKAKFNLLSFTIPLVNPDVWLSRHIDKIRWIWTWEFGFFLCAFISSSVAVWSASVEEVAASHQQLLTAGKIDNAIQVILLTMLVIALHELGHAFTLKHYGGIVKEIGLLFMCLIPGCYTDTTDQYSLVRRKQRVLVVAAGVLIQVTIWALAVWMWLLSQSNPVWHQISYLLMVAALLTVAINLNPLNKFDGYYLLVAGTGINNLRQRSFDFYVDLLRREEIEEAVETQWVLATYAPLSIVYTVWGFSYLMSLIGNWVLLNVPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZG4</accession>
    <name>A0A2G4EZG4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54892">
        <property type="protein sequence ID" value="PHX54892"/>
        <property type="gene ID" value="CP500_013735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="6487" checksum="DC4A04F774DB9B95" modified="2018-01-31" version="1">MWVTITIKIIQCKPDRLLGPNRAPNPIPDPASHPGNLTNLLTEAKIPTTHSLGSHKNPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZK0</accession>
    <name>A0A2G4EZK0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54940">
        <property type="protein sequence ID" value="PHX54940"/>
        <property type="gene ID" value="CP500_013365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="17"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="288" mass="32864" checksum="9A13419E3B0A92F8" modified="2018-01-31" version="1">MTVLTQIEQEEIEYPSSDGEPMAESDITRDYMTYGVEALKLHFHKRWDVYVSANSFVYYEEGNKSAVVAPDIYVVFGVKKRQRDNYKIWKEAGIAPQFVLEITSETTQDVDQETKPETYRSLGVKEYFQYDPSGNYLNPILQGVRLVNNRYESIPANNIAFDTLWLYSEVLGLELHIISGELRLRNPQTGEFLKTYQQSEEARLAEHSARLAEHSARLAEQQARLAAESAFQQSEKGRLAEQQARLATELSLRAVVSHLLNSGTNLEQVAKMMNLSTSEVQRLIGENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZZ4</accession>
    <name>A0A2G4EZZ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55090">
        <property type="protein sequence ID" value="PHX55090"/>
        <property type="gene ID" value="CP500_012510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="373" mass="42825" checksum="021A94D83CCDCF9B" modified="2018-01-31" version="1">MVHFNIGFQHFNSFADITLSLAKTLDKMGIPISVEQSEIAPQITHICTEEENNLIAKWMNNSPSDLFQIKWSHYWKSHFLKELNGHLNFEFFAINYEFTKNDEELDYWMYDAVNNSSHKLAVSEYSKNVLIQAGCPAENISVIPLGFNPLISELYSSKSPKDKSNITSILHMSNSFDFYRFGTDIAIEAFCQEFQHESNVELIIKDGGNNPDVIVEIIRDFEHRCGRFKPKIEIIPKFFDRQELANLYLSADAFLAPFRGEGFAIKILDAFAAGLPVVMPLYGGPTEYANIDNCYPISYDLIPVGLCYDTHHLKISNSPHWAEPNLLSVREQLRNIVADSRRFQVAQKARETADLFTWEATSKKLLRLMRELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F007</accession>
    <name>A0A2G4F007_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54777">
        <property type="protein sequence ID" value="PHX54777"/>
        <property type="gene ID" value="CP500_014240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014951">
        <property type="entry name" value="DUF1822"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08852">
        <property type="entry name" value="DUF1822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="105"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="549" mass="62556" checksum="BF3A052767E89E63" modified="2018-01-31" version="1">MGKIVVLSFIAGDCQQGFQQVRLEIRDDNQRLLGAFIGKLPSAPQIPELYITWQLRYRQMGSRVRIDSPLAQIKNFSRSDLEVDSNALKQQLNNWLKSPEFFPVMEGLLMNVRRDEEVRVIIQTEDSHLRRLPWHLWKFFDDYLKAEVALSSPVCQRINSPKTRNKVRILAIIGDSTGINLKRDQGELEEKLPEAEIVFVREPEKKEVFEAIWDSRGWDILFFAGHSISEPDATTGKLFIKDGKSLEIGDLKLTFRKAIARGLKLAIFNSCDGLGIAKQLADLNMPQVIVMREPVPDMVAQEFLKYFLEGFARGESLYLAVRDARERLESVQREFPCATWLPVICQNPAEEPVSWRELVGTEQSKSEVQDKQVIPRENFSNTFREQRDTTKTALMQEPLILPSEKLVNLGQWLENITEADWQVVTEILETKSLLPLESRRSGSFEGVIRAKSIEFPIEPTSIYLALVVSVTLGASQERQIKLQLYPLHKTSLPLGLKSVALDTFGKTICEVQANNADPWMQLDIEGEPGEQFRLKVELGTASITEDFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F041</accession>
    <name>A0A2G4F041_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000064">
        <property type="protein sequence ID" value="PHX55125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55125">
        <property type="protein sequence ID" value="PHX55125"/>
        <property type="gene ID" value="CP500_012460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="111"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="291" mass="33437" checksum="39134390A48835FA" modified="2018-01-31" version="1">MLQTAKTIQVDRRTGLTHQEFVNEYRNPGKPVIFTDLSKDWPARTKFTPEYFQEEFGDRKIEISGKSYTLNELFELLKKSTKENPAPYPFKLNVRKDFADLEPEISPRPSIAQPDRTHSPLIPNMLLNDLYDLEIFFGGPGGEFPYLHYDFLGLYAYINQVYGEKEFTIFPPEQQKYLYPKPGSPWLSEIENHHNPDLKKYPLLAKATPTTITISAGETLFIPCGWYHTARSLTLTISVAFDQLCESNWEFFTNECCIPRDKNSLKAKMINAYLTGAGALLSARERLMGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F080</accession>
    <name>A0A2G4F080_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55156">
        <property type="protein sequence ID" value="PHX55156"/>
        <property type="gene ID" value="CP500_012295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="301" mass="35021" checksum="92AC5D853440AC19" modified="2018-01-31" version="1">MTRHDTPVEPLPGLVPVATNFNLWPHWELKPISLTLFFLARYSAIFSGIIELSRCDSNVPVNTDEQLRELLQLLKDSQQGSQKQERFKNQLCKLIPDLPGSRKYREPDPKIDFDGALNEAYGGFFKTLPIFFREIDLDNIADDVLRTRVVKRFNKIIQLKILDQYRKLERQPFTFSLDAPTKTKTGEKFDSEGMADDTTEVGIEQLIEREQSKNQQRIGRQLWQYIEDDPECKLRNSYPSDKPDANSQVLARRLLKDPPDKLSVIARELNIKYQTLNSHWKRASLPLLKEIVLEFGYQPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0C5</accession>
    <name>A0A2G4F0C5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_012115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OprB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55198">
        <property type="protein sequence ID" value="PHX55198"/>
        <property type="gene ID" value="CP500_012115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038673">
        <property type="entry name" value="OprB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013428324" evidence="2">
        <location>
            <begin position="29"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="5">
        <location>
            <begin position="182"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="105"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="113"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="673" mass="70964" checksum="8FB2F1B934A17653" modified="2018-01-31" version="1">MSRILWKGLLVSPAVLAASLVLSSASLAAEQPMEIAAATQANNLQLADVTTEAAKAETEALTADQISLATNNTVKTIENANAISQPATTPENTVAADLSTTEPVAEAPVAETSSTVLAANSSEAKPATDSTSTVAPQAQPEQISQSTAPNATSQALPNALQQINQYSAEGTDSENAAAQVTSVSQLSDVRPTDWAFQALQSLVERYGCIAGYPDGTFRGNRAMTRYEFAAGLNACLDKVNELIKGGSKGLATKEDLASVQKLQEEFAAELATLRGRVDALEARTAELEANQFSTTTKLNGEVIFALTGIATGDDANSRDADKTTAFGSRTRLNFDTSFTGKDLLRTRLQVLNLGSFSTNNTKTAEGELRFNAGPFGTASNTVALDALFYQFPLGKSTTVILEANAGAADDFTNTVNPYFDGDGGSGALSNFGTRNPIYYLTAGTGIAVRHQFGEKVELSLGYLAGNAANPTRGNGLFNGSYGALAQLTFKPSDKIALGLTYVNSYNFVTGTGSNASNFPVRLGSFGLGDSSLPVSSNSYGAQASWRVNRGIAVGGWAGYTNQRILSNLGTGASSVQRGDQKIWNWAVTLAFPDLLKEGNVAGFLVGMEPRVTSSTNRTLPEDKDTSLHIEGFYQFKLSDNISITPGLIWLTAPDHNNKNSDLLIGVVRTTFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0C8</accession>
    <name>A0A2G4F0C8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Photosystem II reaction center X protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">psbX</name>
        <name evidence="7" type="ORF">CP500_011935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">PSII consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. PSII forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cellular thylakoid membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PsbX family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55203">
        <property type="protein sequence ID" value="PHX55203"/>
        <property type="gene ID" value="CP500_011935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01386">
        <property type="entry name" value="PSII_PsbX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009518">
        <property type="entry name" value="PSII_PsbX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023431">
        <property type="entry name" value="PSII_PsbX_type_1_subfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06596">
        <property type="entry name" value="PsbX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="39" mass="4260" checksum="11998A6B4865DE88" modified="2018-01-31" version="1">MTPSLANFLYSLLVGVAVVVIPATIALIFISQRDKIKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0D2</accession>
    <name>A0A2G4F0D2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55219">
        <property type="protein sequence ID" value="PHX55219"/>
        <property type="gene ID" value="CP500_012030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7291" checksum="14558F9F2E80E198" modified="2018-01-31" version="1">MLVSILIIDVALVAWSLHLMQEAIAQREFSLMLAGTLVAVSAAALLVVYFLMGSCLSHLSEISQHTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0S4</accession>
    <name>A0A2G4F0S4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55360">
        <property type="protein sequence ID" value="PHX55360"/>
        <property type="gene ID" value="CP500_011215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="80" mass="8491" checksum="100DD93880FB0136" modified="2018-01-31" version="1">MEQAGKPVANYGSPTTHNQTKIFVEQAGKPVANSSSPTTHNQTKIFVEQAGKPVANSSSPTTHNQTKLLVEQASCLLLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0T8</accession>
    <name>A0A2G4F0T8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3146 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55371">
        <property type="protein sequence ID" value="PHX55371"/>
        <property type="gene ID" value="CP500_011270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021492">
        <property type="entry name" value="DUF3146"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11344">
        <property type="entry name" value="DUF3146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="10339" checksum="3381F9B3F3D38A64" modified="2018-01-31" version="1">MSSRPLPETIAYVRVTGQSWQKGTIEGEVTAGGFEWQFQWRFREEKTLILEPSQGRALIQEPLHRFLEKWDYQLEPGGDYSFTVRAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0W2</accession>
    <name>A0A2G4F0W2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55400">
        <property type="protein sequence ID" value="PHX55400"/>
        <property type="gene ID" value="CP500_011035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="15133" checksum="DF251AF8677DB23A" modified="2018-01-31" version="1">MLIIHKELNMKFSADRTEKKGPLGGAYYETYIKITLTPEEENIANKQGIMSSRIFGSMRNSDDPETREAFSLCGRLEITMEDLINGITVKVGSGKELGRLAAFEDLIKQRCKNFKSNLEADQFFGSGGSKDEEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Y5</accession>
    <name>A0A2G4F0Y5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55420">
        <property type="protein sequence ID" value="PHX55420"/>
        <property type="gene ID" value="CP500_011000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8701" checksum="452A76957FD4F5F4" modified="2018-01-31" version="1">MQTTDLFEVIERHPTKVSGAWVFRGTRVPVAAFFENLKDGASIDQFLEWFPGVTRAQVEVLLDHQQQARCLFHKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Y9</accession>
    <name>A0A2G4F0Y9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4926 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55421">
        <property type="protein sequence ID" value="PHX55421"/>
        <property type="gene ID" value="CP500_011060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032568">
        <property type="entry name" value="DUF4926"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16277">
        <property type="entry name" value="DUF4926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="8709" checksum="BEAF7B85A941F982" modified="2018-01-31" version="1">MLKLYQEVALTRDLPEYQLRAGDIATLVDFVPHPSGGEEGCLLEVFNAVGESLTVIAVPISTVEVLRPDEILTVRSLATAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F112</accession>
    <name>A0A2G4F112_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_010830</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55428">
        <property type="protein sequence ID" value="PHX55428"/>
        <property type="gene ID" value="CP500_010830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="299" mass="33469" checksum="94396C630DBBBFB6" modified="2018-01-31" version="1">MLQIEKLNKSYGERSVLRDLTLHIQAGEIYGLLGQNGAGKTSTINILCNLLNADSGKVTLNGEPVSDLTKALIGVAPQENLLYKSLSCEENLNFFAQIYGMNRQQRLDQVEQCLKAVNLTDRAKSPVETLSGGMQRRLNIAVALVHQPKLVILDEPTTGLDIEARYEIWDLIQQLQSQGITILLTTHLLDEAERLCQRIGILKSGSIVAEGSLEELRKLIPAQEIIVVKTQEEAEVIARAEKYNFIPRRYGSDLAFWLPEALELKEIILCFDGISIDSIARYPVRLEHIYVEVTKQTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F128</accession>
    <name>A0A2G4F128_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55484">
        <property type="protein sequence ID" value="PHX55484"/>
        <property type="gene ID" value="CP500_010610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018641">
        <property type="entry name" value="Trfase_1_rSAM/selenodom_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36529">
        <property type="entry name" value="PTHR36529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09837">
        <property type="entry name" value="DUF2064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04282">
        <property type="entry name" value="glyco_like_cofC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="205" mass="22742" checksum="E52BCC00ED99FB76" modified="2018-01-31" version="1">MSEQLIIFTRYPVPGKAKTRLIPVLGKEGAANLHRLMTQRTIATSHVLQKSRQLSVAIHYTDSSQQLMEDWLGTDIIYHQQSEGDLGARMSAALQKSWDLGIDKVVIIGTDCPKLKTEIIAKAFDELSEQDLVLGPAQDGGYYLIGLRRRIPELFDGMKWGTDEVFADTLAIAQNLGLNIAVLPILADIDRPEDLLGLDINILYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F167</accession>
    <name>A0A2G4F167_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Spy protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_010335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CpxP/Spy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55496">
        <property type="protein sequence ID" value="PHX55496"/>
        <property type="gene ID" value="CP500_010335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd09916">
        <property type="entry name" value="CpxP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012899">
        <property type="entry name" value="LTXXQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07813">
        <property type="entry name" value="LTXXQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013834788" evidence="7">
        <location>
            <begin position="21"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="132"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="68"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="161" mass="18534" checksum="0D200CFD6A3251C8" modified="2018-01-31" version="1">MSIRRISALALLMLTLGSTAAAIAVPNPLEPETIAQNQRPNRPGGKEGGMFEKLNLSADQKQKMQAVRDRYKDQISQRMQAVRQARQELQTMMAGATNTSQIRDKHRQIMELRQQLEDVQFESMLSMREVLTPEQRSQWSQLMQQRRESAKNRMQNSPKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F193</accession>
    <name>A0A2G4F193_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative nickel insertion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_010520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the LarC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55530">
        <property type="protein sequence ID" value="PHX55530"/>
        <property type="gene ID" value="CP500_010520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01074">
        <property type="entry name" value="LarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002822">
        <property type="entry name" value="Ni_insertion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36566">
        <property type="entry name" value="PTHR36566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01969">
        <property type="entry name" value="DUF111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00299">
        <property type="entry name" value="TIGR00299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0533">Nickel</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="468" mass="51837" checksum="B00D5A3FD4B3AA00" modified="2018-01-31" version="1">MNKIAYFECPTGIAGDMCLGALVHAGVPLDYLIEKLNLLGISTEYQLRTELVHRNTQQATKFYVDLTADLSLKPQNPVDSTLDPSETESPTFDRSQHHHHTHEPHSHEDDTETGHTSHRHLPQIEQIIVSAKLPERVEAWSLAVFRKLAEAEGAVHGISPEEVYFHEVGATDALVDIIGTCLGLDWLDIDECYFSAMPTGGGTVKAAHGILAVPTPAVMRLWETHRVPVYSNGIDRELCTPTGTAIACTLASGFGPPPSMQIHAIGLGAGSRMLAIPNILRLWIGEKEEGSSAADSVTDVTDGRGKNQEFNQFPMPDSLETIVVLETQIDDLSPQAIGYVFDALFTCGALDVFTQPIVMKKSRLGVLLTVICHPETQAECETVIFRETTTLGIRRSTQQRTILHREFQTVQTEYGEVQIKVAKIGQTITNVQPEYEDCAQIARLKNISWREVHRLALQSWHDQLSMQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1J1</accession>
    <name>A0A2G4F1J1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsH</name>
        <name evidence="8" type="ORF">CP500_010045</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cellular thylakoid membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Stromal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55608">
        <property type="protein sequence ID" value="PHX55608"/>
        <property type="gene ID" value="CP500_010045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="219"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="449"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="227"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="531"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="645" mass="70897" checksum="F1FACD29029E5FCE" modified="2018-01-31" version="1">MHNSWKHAWLGHLAAKKEKSALIPKTSIPGRHLWRILGSLVLSQGILLSTPVFADTAPNTMSYTKLIDNIEKGQVSKIEIDEIQRIARVKLKDKKATDAPQVVTLFDYNNRELYSKIRAKKIDFEVKQTADTSVAVSLVVNLLVILAVLGVLMAILRRSTQSQGNAMNFGKSRARFQMEAKTGVMFDDVAGIEDAKEELQEVVTFLKKPERFTAIGAKIPRGVLLIGPPGTGKTMLAKAIAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFRKAKENSPSIVFIDEIDAVGRQRGAGIGGGNDEREQTLNQLLTEMDGFEGNSGVIIIAATNRPDVLDSALLRPGRFDRQVTVDLPSYKGRLGILEVHARNKKLDPEVTLDNIARRTPGFSGADLANLLNEAAILTARRRKETIANLEINDAMDRITIGLTLNSLLDSKKKWMTAYHEVGHALVATMLKNADPVEKVTIIPRSGGIEGFTSFSLDDEMLDSEGLRSRSLMLNRITVALGGRAAEAEIYGDDEIDTGAGSDIQKVSSLAREMVTLYGMSDLGPVALESPSNQVFMGGEWGSRSQYSEEIADKIDQQIRKIAFDCYAEARRIISENRPLVDRLVEALLDLETIDGDEFRQIVDRYTKSAKKQLAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Q6</accession>
    <name>A0A2G4F1Q6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55407">
        <property type="protein sequence ID" value="PHX55407"/>
        <property type="gene ID" value="CP500_011085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="12"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="196" mass="22962" checksum="9EC855E8FDA445A7" modified="2018-01-31" version="1">MLVQNKQKFYTLDEYRELEETAEFRNEYRDGEIVPIAGSTIDRSQIKGNIFAGLDTALRGKNAEVFISGLRLWISRYRQGTYPDIMVIEGKPALTEGRNDEILNPVLIVEVLSKYSEDVNREDKFRFYRSIPEFREYVLVNQSEFLVTQYIKTESNQWLFREYEGESAMVSFASVEVQMSMSDIYELVVFETLQHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1V2</accession>
    <name>A0A2G4F1V2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Antitoxin VapB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55753">
        <property type="protein sequence ID" value="PHX55753"/>
        <property type="gene ID" value="CP500_009105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019239">
        <property type="entry name" value="VapB_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09957">
        <property type="entry name" value="VapB_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8365" checksum="81AE4C7DD0782A1B" modified="2018-01-31" version="1">MKTPVELNEELVKEAFRLTNFKTEKELIDFALQELIRTRKKRNLLDLSGQIQFSTDYDYKALRENRNVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Z5</accession>
    <name>A0A2G4F1Z5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_008990</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55769">
        <property type="protein sequence ID" value="PHX55769"/>
        <property type="gene ID" value="CP500_008990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037006">
        <property type="entry name" value="CheA-like_homodim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01231">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPt" evidence="9">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="1208"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="8">
        <location>
            <begin position="1448"/>
            <end position="1593"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="1621"/>
            <end position="1738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="354"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="868"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1037"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1079"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="3">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="1671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1749" mass="191316" checksum="47D629078C572E61" modified="2018-01-31" version="1">MLPEQQQRIMGYFIEEAKDHLNTIEQGLLNLQVTIEDPELVNEVFRAAHSVKGGAAMLGLTSIQQTSHRLEDSFKILKECRVKVDQQLESLFLRIFDTLQGQLEQLSGPFGLTEELGEQMVRELEPVFQELNNHLGGLVGYKVGDSDEINLLADSAGAMDRASFAASSEKFLGSGFACDRAQGHQGSMRLVFESDVPARMREMLQEFKQPESEESRGRLRGICGSLRRLGEEFNLSCWMGLIEAGERAIDNRENSYRTLAPVVIKEIKQAQDLVLSGMESEIVVSAKLRELAQIVTPEADFEDLLAFAQPGADAGGMTGQDEVWDLVRAEENSSAELIRPTISGLSMDELFDVGANGNSPLPGDSNDYGGGRSPQFGDSPGFGDSELETATFKMSTHTGPEVGAAELNTLADLFDGESPDLDGGWEGEDEIEETSFSRIQTRGLLEMDDEDGSVDFTDLLLDDYDVASSEVNTVPPIEDFTSLFGPDALGGGELWGSEQSPSLKQRDLTTDNAVAVNKNRSENRGEWPFAPTVEGWRSDDALGNLLDEVAAQTSVTVDDADLDLFSESEASEDLDLSEWSFAPTDDLFWEEDQNTGELPFAPTDQEAHNPEIDNLFDVTPNADLDISEADHWLEDAFGVEEESLSLGDDSSQSDGDLDALFDSVSLDAVGESEQMEGRLSSAGVKSQATADLVELFDSVPTGIDDYGEDLEDVDTEDWLNFEEDARSGSEDLGNELDRPVLTSSDNHLTTETMVTKGSADDRSDFDNGNTFDLLEDMFGEGIVSADVVGTVESGDLEKLSTDITDSSFDEDEVDLFDAFSIDLTADDDAEDDLFSALETEISSGDLEAMSASLDDESFEENAELLVGANGDSPRANGDSPLQETGATLDSSDLDGFDDLLDLIDAGPLVTSVGANGDSPWANGHSLAGFWDTEELSEESEFDTESLSGFFDTAETSLEDTEESFDDLESLLNLGDTGAIIAGAQLTNQSRGELPFDQGELPFDQGELPLAQGELPFAPTEVFSDLEEMLGESKTVPEISLSTGAERSRSRGELPFAPTAPQHGLDDDFSDLEALLDEPKEGARQGEGNISSRLGSIRPKGPRQGFGDQTMRVPVKQLDNLSNLMGELVVNRNSLEQDQERMRQFLDNLLHQVTLLSDVSQRTQDFYERSLLEIALLANRQGHRSAWRSEEQSHHRDGAWKPEEMDRFTPFHSLAQEIIELIVRVRESAADIEFLVDEADQVTRQLRQVTTQLQEGLTKARMKPFAETTDRLFRAVREIGIKCGKQAQLQVEGKDILIDKMIVDQLYDPMTHLVNNAITHGIESPEVRLAAGKPAMGRITIQAFQQGNQTVISVSDDGAGIDPQKVKAKAIKQGLLTAAQAQRMTRIEVYELLFRPGFTTQEQATEFAGRGVGMDVVLTSLQEIRGTVSIDSTIGKGTVFTIRLPLVLSISKALCCISDRARIAFPMDGVEDMIDVPRDQVTTGVDGLPCIDWRGTILPFRPLRELLAYHRHLGRGSVYGFNTDDDMISVIVLRSAGTFLAVQVDQVSTEQEIVIKQLEGPVPKPIGIAGATVLGDGKIVAIADVLELIDLATGRLRKDAGGTLWEGDRVPVEPIEEKAEPTVLIVDDSITVRSLLSITFEKSGYRVEEARDGKEAWEKMKSGLPCDIVFCDIEMPRMDGLELLSRMQKDSVLCELPIAMLTSRGADRHRQMAYGLGAKGYFTKPYLEEQLLDAASRMLKGEVVGAPAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F205</accession>
    <name>A0A2G4F205_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55507">
        <property type="protein sequence ID" value="PHX55507"/>
        <property type="gene ID" value="CP500_010395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="11011" checksum="2956272D9B3BEE36" modified="2018-01-31" version="1">MKIPLTSACRHCRHYMPEGRRGGVCQQLSVPVQGQWKACSLAVSPFGPSWDNIEELPLWQEQVATLPEPTVAVSERNSCQLTRTTLTEKSLPTLSVEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F206</accession>
    <name>A0A2G4F206_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chemotaxis protein CheW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55779">
        <property type="protein sequence ID" value="PHX55779"/>
        <property type="gene ID" value="CP500_009005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="28"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="19608" checksum="F185FF5304DECA9E" modified="2018-01-31" version="1">MSGSSDFILPGLGIDHAPEFQELETPEGELHLRFYVPSGNEFALPATGIREVLSPSPDRMTPIPNVSSLLLGTLNMRGRVIWVADLGQFLGDPTPMNTDRPEIPIIAVEDQDTILGLAVDRIVGMDWLDVEQLHSQNNAPDGMMPFLRGEWMLGEPVQKVLRLLDQVKILRSARWAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F213</accession>
    <name>A0A2G4F213_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Urea ABC transporter permease subunit UrtC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">urtC</name>
        <name evidence="7" type="ORF">CP500_008925</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55800">
        <property type="protein sequence ID" value="PHX55800"/>
        <property type="gene ID" value="CP500_008925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017778">
        <property type="entry name" value="ABC_transptr_urea_perm_UrtC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482:SF4">
        <property type="entry name" value="PTHR30482:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03408">
        <property type="entry name" value="urea_trans_UrtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="380" mass="42026" checksum="4C2B05590B8045B8" modified="2018-01-31" version="1">MQNTHQKAWIKEAAIVGAIALILILLIPGILPDVRLNQLGRFLALAIAALGIDLIWGYTGLLSLGHGVFFAIGGYALAMHLKLQIPPTASSQLPEFMNLYGVTELPWFWQPFNSFPFSALAVILIPGLLGAILGYLVFRNRIRGVYFSILTQAATIVFFNFFNGQQKLINGTNGLTDFKTLFGATINDRDTQYIFYILTILFLAATYALCRWLTSGRFGRLLIAIRDDEIRLRFSGYNPTGFKVLVFAISAGMAGIAGALYTVQTGIISPKAMDIAFSIEMVIWVAVGGRATLSGAVLGTLLVNFGKSFLSEQFPEVWLFFQGALFLIVVTVLPDGLVGWLQKQGIDQIRSLFRKPKYVSTYPSLEQDPEVLHEKEEIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2I8</accession>
    <name>A0A2G4F2I8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GUN4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55970">
        <property type="protein sequence ID" value="PHX55970"/>
        <property type="gene ID" value="CP500_007950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16383">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008629">
        <property type="entry name" value="GUN4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037215">
        <property type="entry name" value="GUN4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34800">
        <property type="entry name" value="PTHR34800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05419">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140869">
        <property type="entry name" value="SSF140869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GUN4" evidence="1">
        <location>
            <begin position="14"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="185" mass="21338" checksum="0B1C264220F0C02D" modified="2018-01-31" version="1">MLKTEDDEVKLVSALGLDYSNLRDLLASQKWQEADRETAILMLRGAKREEKGWLNRESIEGFPYEDLHTIDQLWVKYSNGHFGFSVQKRIYENVKEHSEDESEVWPTFRYMVNWLKKGEKFQYSDLNFSEKAPEAHLPVVALFVGFLGTEIESESFEKQCAVMAGLGGVVFEAIGSRLLNCNIQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2P3</accession>
    <name>A0A2G4F2P3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 57 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56018">
        <property type="protein sequence ID" value="PHX56018"/>
        <property type="gene ID" value="CP500_007645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004300">
        <property type="entry name" value="Glyco_hydro_57_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03065">
        <property type="entry name" value="Glyco_hydro_57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_57" evidence="2">
        <location>
            <begin position="8"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="748" mass="85895" checksum="3CBE99D1CA28EB99" modified="2018-01-31" version="1">MSHPLYVAFIWHQHQPLYKSRVSANAKEAQYRLPWVRLHGVKDYLDLVLILAKYPKLHQTVNLVPSLILQIEDCIADRALDPYLAAALKPVEDLNKSEKEFILQHFFDANYHTLIQPHPRYDRLYSQRQENGIQWCLENWNQHDFSDLLAWHNLAWIDPLFWDDPEIAGWLKQGQNFSLADRQKIYSKQKEILARIIPQHRQMQADGQLEVSTTPYTHPILPLLADTNGGRVAIPNMTLPQHRFQWAEDIPRHLRKSWDMYQDRFQCEPRGLWPSEQAVSPEILPYIAKQGFKWIVSDEAVLGWTIKHFFNRDGAGNVCEPELLYRPYRLETPDGDLAIVFRDHRLSDLIGFTYSSMEPKKAASDLVGHLEAIARTLKHRQSSGTTTLENPWLVTIALDGENCWEFYPQDGKPFLEALYETLSLDPDIKLVTVSEFLDKFPATETIPAAQLHTGSWVDGSLTTWIGDPAKNRAWDLLGAARQVLANHPEATEESNPEAWEALYAAEGSDWFWWFGEGHTSNQDAMFDQLFREHVAAIYEALNEPVPPEVRSQVEAHEAPGDHQPMSFIHPVIDGIGNEQDWDKAGRIEVGGARGTMHRSSAIQRIWYGVDHLNFYIRVDFNAGIRPGIDCPPELNLFWFYPDRTMQNSLIPLSDLPDTAPLNYRFRHQLRINLLTKSIGFQEAGEHDEWHPRISRAQVGLDKCLEVAVPWADLQIMPDWSLRLIAVLSEGERFSSCLAEDALIAIGMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2U2</accession>
    <name>A0A2G4F2U2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RusA family crossover junction endodeoxyribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56094">
        <property type="protein sequence ID" value="PHX56094"/>
        <property type="gene ID" value="CP500_007250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008822">
        <property type="entry name" value="Endonuclease_RusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036614">
        <property type="entry name" value="RusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05866">
        <property type="entry name" value="RusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103084">
        <property type="entry name" value="SSF103084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14830" checksum="3E362645D81F5D86" modified="2018-01-31" version="1">MQFEFLIPKRPVSLQTRQRSKLQNWQAFVRAEALKTWVGNPYSGNVHLTLVYLYDADPVDTDNIIKPIQDALIGLVYEDDSLVTDVESHRRSLSDTFDVALCPLLLVRGIISGSDCVYVRINSAKALESYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2V3</accession>
    <name>A0A2G4F2V3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Trypco1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56104">
        <property type="protein sequence ID" value="PHX56104"/>
        <property type="gene ID" value="CP500_007300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045794">
        <property type="entry name" value="Trypco1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19493">
        <property type="entry name" value="Trypco1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trypco1" evidence="2">
        <location>
            <begin position="17"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="13146" checksum="98C7B889D5882179" modified="2018-01-31" version="1">MSELERFAFQEKGEVYEVTIDEATTSDDDSPFDEERGLGSDALNRMQQARLLIRNYAMYAVTAFKDFGAAEVEEVTLKFSIKMGGKTGIPYITEGSAESNLEIEVKCKFPKSPANENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F320</accession>
    <name>A0A2G4F320_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_006805</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56149">
        <property type="protein sequence ID" value="PHX56149"/>
        <property type="gene ID" value="CP500_006805"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="302" mass="32266" checksum="7947BA244B9CF6FA" modified="2018-01-31" version="1">MSRILSGIVAIVVALGMIILGGWYFTIGFGIIVYLGQLEYFQLARAKGIAPAAKTTLVVSQVLLITAALAPQLVDAMFPLAGTLICFYLLFQPKLSTIADIAASILGLFYGGYLPSYWVRLRVGLDPAYQATTGLGQAVASNLPIQIYPQSWTNLSNISLGLTSLLLAFLCIWAADIGAYFVGKFFGRTSLSHISPKKTVEGAVFGVCGSIAVAVAGSWYLNWPGWPYTGAAFGLLIGVASLLGDLTESMMKRDAGVKDSGQLIPGHGGILDRTDSYVFTAPLVYYFVTLLLPAIDSFLINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3A0</accession>
    <name>A0A2G4F3A0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56253">
        <property type="protein sequence ID" value="PHX56253"/>
        <property type="gene ID" value="CP500_006440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="14672" checksum="79F1CD399E49041C" modified="2018-01-31" version="1">MEINKEIRNLIIDYAIGAAILGLNPLPGTLTVTLLAASVLLLKMMRDIGAKWGYPKGQDILAIGGNIFGGFGSFWIAFMAWISMYVTGLFVPFVGGFAVALSLFALTWRIGQATHLYYASGSQNRQLSNLKSKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3F1</accession>
    <name>A0A2G4F3F1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56276">
        <property type="protein sequence ID" value="PHX56276"/>
        <property type="gene ID" value="CP500_006335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="218" mass="24090" checksum="9AA5F0F54D9E4143" modified="2018-01-31" version="1">MEENRAPAYLQLIHTLLNCPNGDEPQILQDNSELLDRGFLETCESVAAKLAEQGGENGANFLRNLASQLAQFMEMNDDGNSNNSQGESSQESANFFLELLQAEEASNSDIQVIHPMLEQRQHLLNARFAEILQQVAQKLLAGENLATINSIVTLIENLSIHIMDFPYGNRANNIQIAISGYQIVLNNREPGSEKFAQTQNNLALAYSETINGSQANNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3F4</accession>
    <name>A0A2G4F3F4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56300">
        <property type="protein sequence ID" value="PHX56300"/>
        <property type="gene ID" value="CP500_006095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="252" mass="25647" checksum="EE72CF1F2D480247" modified="2018-01-31" version="1">MTLKSNVENGISRLLGDNTSESITLSPGQLTNIPGGVWVLGGNDTVIGSADSELILGNDGQDSISGGAGNDTLIGGKDNDFVDGGIGNDSIRGDSNEDIIRGGDGNDSLFGGKGNDQLFGDAGDDFLSGDQGNDTLTGGLGNDRFVLSTGGGLDIITDFGNGSDFIQVPAGVSISDILIQTAGSNTLLSLRSTGEQLAQLNNVQASSITTGTLLLPNQPLLQSTPPPINIPQPPSEIPIPLLPDVPLPPIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3T1</accession>
    <name>A0A2G4F3T1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system PemK/MazF family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56398">
        <property type="protein sequence ID" value="PHX56398"/>
        <property type="gene ID" value="CP500_005655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12508" checksum="64049D14ADF1223F" modified="2018-01-31" version="1">MTSYNFGDVVLVPFPFTDQTTNKKRPAVVISSDVYNAEYLDRILMGITSQVSSSPKVGDIIITDWRSAGLLKASLIKPVITTIEKQLILKKLGRLQDVDIKSLKEGLIGIIGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3U4</accession>
    <name>A0A2G4F3U4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56405">
        <property type="protein sequence ID" value="PHX56405"/>
        <property type="gene ID" value="CP500_005695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012667">
        <property type="entry name" value="CbtB_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09489">
        <property type="entry name" value="CbtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7338" checksum="1B43AB3BE09D696B" modified="2018-01-31" version="1">MTTQSSSSSSSILQQTARLTLSTPVQATLYISLCALTVWTVYFTTYPAVHDKVHSLRHHTLMVSCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3X9</accession>
    <name>A0A2G4F3X9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56448">
        <property type="protein sequence ID" value="PHX56448"/>
        <property type="gene ID" value="CP500_005450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="12142" checksum="4F3FE07196C49077" modified="2018-01-31" version="1">MLVHSRYADGTIVLKSQQPPRLGEAKPDPNAIGPHSQLRWDTYNQRIYQMREFDQSGQPVRDIDFTSPTYPNGNPRPDHLPPPHQHQWIPNLTGGTPTRNKIPELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F439</accession>
    <name>A0A2G4F439_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56508">
        <property type="protein sequence ID" value="PHX56508"/>
        <property type="gene ID" value="CP500_004955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="19"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="193"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="243" mass="28382" checksum="A1516E6A6E2975AF" modified="2018-01-31" version="1">MSLAIEKLPIDLITDDGEPMESNNHRVSMNVLIQSLKYHWRDRQDFFVGGNMFVYYSANQVKNQDFKGPDFFVVLDVDGTTNRDAWIAWEEDSRLPDVVIELMSPSTAEVDLTTKKDIYERKLKTQDYFVYNPKNSNSLRGWQLINRRYQSLSPNQQGRLYCESLGLWLGIWEGQIENSQGNWLRFFDTDGNLVLMGDEAETQRAELERHQKEQAIQQLEIEKQQKEKLAAKLRELGINPDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4G0</accession>
    <name>A0A2G4F4G0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56636">
        <property type="protein sequence ID" value="PHX56636"/>
        <property type="gene ID" value="CP500_004295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="228" mass="24195" checksum="084F8535021A2741" modified="2018-01-31" version="1">MVLNSTVVLTLILLTLMFGAGVTSSVWGFTLGREALKGTTQPDVRPSSNAGGKQGTPAKSDQVSILKEKDILKIVKARVDGRDPEKLATQNAKDKASSKPATAKKTPTGQNASAKFPMNSRDGGITLEVSAVNQRGNSMLLDVSMKNEGSQAVRFLYSFLNVTDNQGRPLSATAEDLPAELPPNGQIFYGTVSIPTALLENAKELSLTLTDYPGQKLQLQIAGIPVPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F549</accession>
    <name>A0A2G4F549_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56617">
        <property type="protein sequence ID" value="PHX56617"/>
        <property type="gene ID" value="CP500_004485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11099" checksum="F2C0A45F1AA1BF14" modified="2018-01-31" version="1">MESVKRIEIIAHSVELGKILDGLDKAGVQGYSVIRDVAGKSTRDHVSRDSSMTMLDNIYVLAFCEPDQVSAVAENIRPVLNRFGGSCFISDAVELLITRCVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F576</accession>
    <name>A0A2G4F576_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56910">
        <property type="protein sequence ID" value="PHX56910"/>
        <property type="gene ID" value="CP500_002720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8578" checksum="815A785295088865" modified="2018-01-31" version="1">MASYTADKKKNSFTKVQMNYEADQVLQLYFKENTNRIEKWFNIISPGNDSMQKLHSQIAQLRDKNWQIIHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F577</accession>
    <name>A0A2G4F577_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56888">
        <property type="protein sequence ID" value="PHX56888"/>
        <property type="gene ID" value="CP500_003180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="11091" checksum="8B000777495FF919" modified="2018-01-31" version="1">MANNDFKVIQIIEAKGWYAFGSTKQSQHVERWVRPVVCWVLIEDKKKRRIVTATASYQIEIDDKEVEFFAHESEIQDIESLPKSVSVSEFLKTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F588</accession>
    <name>A0A2G4F588_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56895">
        <property type="protein sequence ID" value="PHX56895"/>
        <property type="gene ID" value="CP500_002645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044256">
        <property type="entry name" value="HCF244-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47128">
        <property type="entry name" value="PTHR47128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="6"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="291" mass="32310" checksum="A69B4764BA6BA6D0" modified="2018-01-31" version="1">MFLVTGATGALGRRIVREIRQQEKPVRAFVRLASRYSELENRGAEIFIGDLKQDKDIKKACQGVKCVISTHGTGGDVQAVHYRANIELIDCAKEAGVEHFVFISVLGVDRGYEDSAVFKAKREVEKYLQNSGLNYTILRPAGFASSLLPSAERFRETGLYLLIGDGKNRTSVVSTDDLAHIAVDSPTVEGARNQILPVGGPDVLTRDDIARIFGRLFDREPIVISPPLVVFDGLRNALGLLNPQAQKDLGTLRVLLGNEFFCTPEEVQRLESIYDMRMESLESFLRRNLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5B7</accession>
    <name>A0A2G4F5B7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YihY/virulence factor BrkB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_002940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56950">
        <property type="protein sequence ID" value="PHX56950"/>
        <property type="gene ID" value="CP500_002940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="338" mass="38086" checksum="B7EFD967A1668440" modified="2018-01-31" version="1">MNIFYWLRYLILALFRVLLRLLRAIKNKFGHFWLFCRCLTWRTLREVCVKAGEQRLPGLSAEMAYNSMLALFPGLLAVLSAIALFEPLQSTLYQIAGLLGEVIPDEVRKLIRSSLEEILLYRNQELFSLSFVASLWAFSGVMSAAMAALDRIHEISPDRTRSFLKAKLIALALSIGTIILLIIASGAVFVSDLIVQAIARQSCLLESVANCNLKEFKSCLLPATSCPLESELLAIWWLWRWPSSLGIVSVAFAFVYRYGPSRHQRDIPIFSGAVFAAILWALISALFRFYVLHLGNYSWTYGTIGTFIVLLLWLYLCCLVMLIGAQLNVTVGKAMKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5E7</accession>
    <name>A0A2G4F5E7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1460 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56955">
        <property type="protein sequence ID" value="PHX56955"/>
        <property type="gene ID" value="CP500_002375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010846">
        <property type="entry name" value="DUF1460"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07313">
        <property type="entry name" value="DUF1460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="352" mass="39404" checksum="319A8A97867D91A9" modified="2018-01-31" version="1">MKQNPFKNMRNFWGLAVLGLIMVGVSNSLIPAVSVFQPQSATAEAIVDRQIGIRQLDSNHITTETAVLPEDIAHFERVVKYAKQQNLPDRSMGQIIQAIGDYFLGKPYAEGLLDKSGTEKLLITLDKFDCVLFVETVLAIARGVVVQDYDYQNFANRIESQRYLNGKMNGYCSRLHYFSEWINDNQKRQTVENITAKLGGIPMDKKLNFMSQHRSSYPQMSKDETTYQCIVNIESDLAKSTVNYIPENRIKSIYSQLQPGDIVAVATAVKGLDVTHTGLVYRNRDGNIGLIHASPAGQVTVAYDLHRYISRVESAIGIVVARAIDPRQNGVRLNSYVAPFSRTGKMPVPQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5J5</accession>
    <name>A0A2G4F5J5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_002315</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57042">
        <property type="protein sequence ID" value="PHX57042"/>
        <property type="gene ID" value="CP500_002315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="154"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="383"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="417"/>
            <end position="424"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="631" mass="69786" checksum="CC70D8CC88278770" modified="2018-01-31" version="1">MSRPDTYPQTMQPIKITTFQALRRSLGLIIKAAPIELRNLILLNIIRGAAPSGVLFLDKLIIDEVSRLLSQTQTAQPFALMLAHPILLWSIAGVLSLKLVGDSLETMSSFASTSLRDRVQGFVEGKVLEKVANFDDIALFENPELLNIVELAKTGVKQVQQLAFTLSMTITGVFIFIPSIGLAATIAWWVPMLMLISSSPSIYIQRKYSRIIWRVQRKQAKISREMNLSARVLTGEEYAKELRLFGLQELWLKRWQGQFLQFFSEMQRIRKKGAVVVLFWSVFSRIGVALPFVYVVMGALGGRYTLGDLALYSGLIVQVEQSLQLLIGNYTNLYDISLSVTPIFQLLDLKPELQSPLVDVSSRLFSLPDGGQDARATKDKIGIEIEHLSFCYPGSNKNTVEDINLTIQPGEMLVVVGENGAGKTTLGKLLGRLYDPTSGSIAWNGKDLRSLNLAYVRSHIAVVMQDYARFPSTVRENVGFGDLLSLSDDTAINEAISEAGIAAKVNSLEQGLETPLGKQLEDGIDLSGGQWQRIAIARALMRLSTAEVLIFDEPTAALDPKTEHEIYSIFRQIAAGKTTVVISHRLGLAKIADRIAVMENGKIVEIGTHDELITSNGIYCSMFTRQASSYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5R4</accession>
    <name>A0A2G4F5R4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pepA</name>
        <name evidence="10" type="ORF">CP500_002120</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57096">
        <property type="protein sequence ID" value="PHX57096"/>
        <property type="gene ID" value="CP500_002120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="9">
        <location>
            <begin position="341"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="492" mass="51742" checksum="AE468161B3893074" modified="2018-01-31" version="1">MEFRVTDTPRSVWTGDALAIGLFEDAVELTGDLAQLDEKLMGTLKELIEEADFKGKAGTSAITRVGGNSPLRKIAIVGLGSSDHLKLDTLRQAAGICAKLAKKEKCQTLGISFPVWKNAPDATASAIVEGVELALHLDHRFKSEPEDKSGAIDQIDLLGFVASESAIVRARQITAGVILARELVAAPANSVTPITMAETAQSLAAECGLELTILEREDCEKLGMGAFLGVAQASDLPPKFIHLIYKPAGKPRRKIAIVGKGLTFDSGGLNIKGVGSGIEMMKIDMGGAAATLGAAKAIGHIKPDVEVHFISAVTENMISGHAMRPGDILTASNGKTIEVNNTDAEGRLTLADALVFADKLGVDAIVDLATLTGACVVALGDDIAGLWSPQDSVASEIVAASEMAGEKFWRMPMEDKYFEGLKALHADMKNTGPRPGGAITAALFLKQFVKDTAWAHLDIAGPVWTEKENGYNGPGATGFGVRTLVHWVLGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5W3</accession>
    <name>A0A2G4F5W3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57183">
        <property type="protein sequence ID" value="PHX57183"/>
        <property type="gene ID" value="CP500_001260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="198" mass="22199" checksum="9BD6AE77CD4FAA26" modified="2018-01-31" version="1">MVEILIWSLMVGSLGLESVIAGKFVNREQLARRQKSDEEEEVLTRYESQEEHLAGRDHSLSNGNSIADGTVLEYKIVRASSDLFRNPAIFQRLCREEAEFGWILLEKLDDRRVRFKRAIALRDTQRPDLPPFDPYRTHYGPMLNGTNLAGAIVFLSAMLLPAVLGYTLVSTTLIKSRSNLAPAPIQSMPSPGTPDNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Y9</accession>
    <name>A0A2G4F5Y9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_001220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57176">
        <property type="protein sequence ID" value="PHX57176"/>
        <property type="gene ID" value="CP500_001220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006189">
        <property type="entry name" value="CHASE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042240">
        <property type="entry name" value="CHASE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03924">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01079">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50839">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE" evidence="8">
        <location>
            <begin position="76"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="7">
        <location>
            <begin position="444"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="385"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="618" mass="69139" checksum="437CB89C6BB5FCAB" modified="2018-01-31" version="1">MLKKLPLPWSRYTPAGLTLTLGIGLSALAFVLVWNWENGRWDYQTNRSIDDISIALERQINSDLDAVLALSDYMKAFRTVDRSSFARFVGRPLSVHPSLQILAWVPRVPNRDRANYEAQNNPNFQITELSPQRKRIQAGQRSEYFPALYVEPATNNKTIVGFDFASHPEIRAALSRGRDTGEMIVTGQIGLIENNSSEVDLLAIVPIYTNSAKPTTIKSRRELLQGFVVGVFRGKDIFQTSLKGRNTDYLNIYLSSEAPGKQEASVLSARTSPPIFRDTTAKGQINQFSVLFKSASQQVFLAPADVPQEVKLSCPILQNPAPDYTACRRLPKINDREWSLYVSATAEIRKSRKHWRSWGTLTMGMLWTLIPVTYMLTALSRTAQIEKLAQERARQASQLQDAYQQLEAEQAKSDQLLLNVLPAAIVQRLKRNEKNIAESFGEVTVMFADIVGFTELSSRISATAVVEVLNDIFSAFDHLADRHGLEKIKTIGDAYMVVGGLPTPRSDHAEAIAAMAIDMLQEIRRLSLDYSEPFSIRIGIHTGPVVAGVIGLKKFIYDLWGDTVNIASRMESHGITGCIQVTTETYEILKDKYTFQKRGAIQIKGKGYMITYLLTGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Z4</accession>
    <name>A0A2G4F5Z4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplE</name>
        <name evidence="5" type="synonym">rpl5</name>
        <name evidence="9" type="ORF">CP500_001755</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57145">
        <property type="protein sequence ID" value="PHX57145"/>
        <property type="gene ID" value="CP500_001755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="7">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="8">
        <location>
            <begin position="85"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="181" mass="20448" checksum="6DA65151368DB26B" modified="2018-01-31" version="1">MPDKLKVLYQEKIVPKLMDQFKYTNIHQVPKLLKVTVNRGLGEASQNAKALDSSINEIGIITGQKPVVTRAKKAIAGFKIRKGVPVGVMVTLRSDRMYDFLDRLINLALPRIRDFRGISPKSFDGRGNYSLGVREQLIFPEIEYDSIDQVRGMDISIITTAHTDEEGRALLKEMGMPFRDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F669</accession>
    <name>A0A2G4F669_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_000945</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57239">
        <property type="protein sequence ID" value="PHX57239"/>
        <property type="gene ID" value="CP500_000945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="383"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="416"/>
            <end position="423"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="666" mass="73777" checksum="1D0988E7A460E45D" modified="2018-01-31" version="1">MSETVLEVRNLRVEFGSADAGDASATVKAVDDISFEVKRGQTLGIVGESGSGKSVTSLAIMGLLSSVSTQISGEIWFSSTKDGASKEPVNLLEMPSQEKQIYRGSQMATIFQEPMSSLNPVFTIGFQLTEAICLHQNVSQIAARRQAASLLQEVKLLPDDEELKQRCLFQKQQDFSADGPDGTTDDRDLMQLINDQKQAMLDRYPHQLSGGQIQRVMIAMAISCNPTLLIADEPTTALDVTVQATILALLRELRDSRGMAMIFITHDLSVIAEIADVVAVMYRGKIVECGAIEQIFSNPQHPYTKGLLACRPTLEKQLRRLPTVSDFMDVTTNASGELVIVEKDVDLDSDSSSGLSAFATGKAPRLPNLGAPLLTVNNLRVGFPVQGVFGETKRLFMAVNDISFEVYPGETLGLVGESGCGKSTLARSLLQLIPISSGQVFFEGQEITPPAYNISQWRWMANYRIQKEYARKLRWLRRDLQIIFQDPFSSLDPRMNVGAAVMEPMVIHSVGKNQQEQRDRAAYLLDRVGLNPDFMGRYPHEFSGGQRQRICIARALALNPKFIICDESVSALDVSVQAQVLNLLKELQTELGLTYMFISHDLSVVKFMSDRAIVMNQGKIEEIGTAERIYRQPQQVYTRQLIAAIPAGNLERIRQQQLGRNTSFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6N3</accession>
    <name>A0A2G4F6N3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57416">
        <property type="protein sequence ID" value="PHX57416"/>
        <property type="gene ID" value="CP500_000310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="225" mass="25471" checksum="D2020BC8AC67506D" modified="2018-01-31" version="1">MDYQKFFNLVPTFYENWGEETVQPKNNGFRQVKEQISCMTTVNVMQLLNFAVSCMELDEAYCEVGCFQGGTLVGALLNNPGKTAYAVDNFSKFDDSGENFTTLKNNLSNFGVADQVVFNNQSMEDFFLKLKEVKATNPKFGVYLYDGAHDYRSQLLGLMFAKPFLAAQALIIVDDTNWKDVSQANKDFIDTHPQCELLLDLPTPHNGCETFWNGIQVLSWDASRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6P7</accession>
    <name>A0A2G4F6P7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF448 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57371">
        <property type="protein sequence ID" value="PHX57371"/>
        <property type="gene ID" value="CP500_000045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007393">
        <property type="entry name" value="DUF448"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037465">
        <property type="entry name" value="YlxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035931">
        <property type="entry name" value="YlxR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34215">
        <property type="entry name" value="PTHR34215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04296">
        <property type="entry name" value="YlxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64376">
        <property type="entry name" value="SSF64376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YlxR" evidence="1">
        <location>
            <begin position="6"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="88" mass="10030" checksum="2A0334DB5D4CBC48" modified="2018-01-31" version="1">MKPNYRCCASCRKIAPKEAFWRVVRLYPSHQVQLDLGMGRSAYLCPQAECLKAAQKKNRLGRSLKAPVADQLYQTLWQRLATSDCADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-12-20" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2A5P8J0</accession>
    <name>A0A2A5P8J0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system HicB family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017265</name>
        <name evidence="2" type="ORF">CP500_017300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54216">
        <property type="protein sequence ID" value="PHX54216"/>
        <property type="gene ID" value="CP500_017265"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54222">
        <property type="protein sequence ID" value="PHX54222"/>
        <property type="gene ID" value="CP500_017300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7849" checksum="7AB87C2A4C955765" modified="2017-12-20" version="1">MKNRSFTVLLYKEDDMYIAECPEVGTVDQGETIEQAIAGLREATRLYLEEFPVPETSPRFVTSIEVSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUC9</accession>
    <name>A0A2G4EUC9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative pterin-4-alpha-carbinolamine dehydratase</fullName>
            <shortName evidence="4">PHS</shortName>
            <ecNumber evidence="4">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pterin carbinolamine dehydratase</fullName>
            <shortName evidence="4">PCD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_023105</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000265">
        <property type="protein sequence ID" value="PHX53141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53141">
        <property type="protein sequence ID" value="PHX53141"/>
        <property type="gene ID" value="CP500_023105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00434">
        <property type="entry name" value="Pterin_4_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTHR12599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="SSF55248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="93" mass="10391" checksum="B0333851D9D4770F" modified="2018-01-31" version="1">MASLLSDTEIQKRFSQLSGWTVEGNQLRCTWEFKDFIAAIAWVNKLVEPSEAAAHHPDIEISYNKVTVNLTTHDAGGLTEKDFALAQQISQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUP2</accession>
    <name>A0A2G4EUP2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000228">
        <property type="protein sequence ID" value="PHX53259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53259">
        <property type="protein sequence ID" value="PHX53259"/>
        <property type="gene ID" value="CP500_022460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="13332" checksum="0720C9AB249DD336" modified="2018-01-31" version="1">MLIYEAFHNTLKRYDISGKALARVAGVSESLVSQFRHGKKGVTDEMLDNLLEAMQKIAPGARKHFCSLVAGELVCGAGVENAIKEISAEEIPELLMAIARCWKSVDHPSIYATSALMEFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUW6</accession>
    <name>A0A2G4EUW6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="6">RPPK</shortName>
            <ecNumber evidence="6">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="6">P-Rib-PP synthase</shortName>
            <shortName evidence="6">PRPP synthase</shortName>
            <shortName evidence="6">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prs</name>
        <name evidence="8" type="ORF">CP500_022125</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000215">
        <property type="protein sequence ID" value="PHX53325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53325">
        <property type="protein sequence ID" value="PHX53325"/>
        <property type="gene ID" value="CP500_022125"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_B">
        <property type="entry name" value="RibP_PPkinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037515">
        <property type="entry name" value="Rib-P_diPkinase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="7">
        <location>
            <begin position="22"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ribose-5-phosphate binding" evidence="6">
        <location>
            <begin position="241"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="55"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="330" mass="36253" checksum="1F6B2205155AAAE4" modified="2018-01-31" version="1">MIRSATLPLPLPEQSVSPHDRLRLFSGSANVPLAQEVARYLGIDLGPMVRKRFSDGELYVQIQESIRGCDVYLIQPTCCPVNDRLMELLIMIDACRRASARQVTAVIPYYGYARADRKTAGRESITAKLVANLITEAGAGRILAMDLHSAQIQGYFDIPFDHVYGSPILLDYLKSKQLTDIVVVSPDVGGVARARAFAKKLNDAPLAIIDKRRQAHNVAEVMNVIGDVRGKTAVLVDDMIDTAGTICEGAKLLRREGARQVYACATHAVFSPPAIERLSSGVLEEVIVTNTIPVPEEKRFPQLTVLSVANLLGETIWRIHEDSSVSSMFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUY8</accession>
    <name>A0A2G4EUY8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">def</name>
        <name evidence="3" type="ORF">CP500_022340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000224">
        <property type="protein sequence ID" value="PHX53276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53276">
        <property type="protein sequence ID" value="PHX53276"/>
        <property type="gene ID" value="CP500_022340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="176" mass="20068" checksum="CACFC8FA17EA714A" modified="2018-01-31" version="1">MSEILQISQLGNPVLRRRSQIVENILDDRLQQLIDNLIYTVQQANGVGIAAPQVAMGDRIFIVASRPNLRYPQAPHMEPTAMINPRIIASSTETVKDWEGCLSIPGIRGLVPRSRSIEIEYTSRDGQLHRQEFTDFVARIFQHEHDHLDGIVFLDRVESTQELMTEDEYCKTLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUZ2</accession>
    <name>A0A2G4EUZ2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lspA</name>
        <name evidence="9" type="ORF">CP500_021945</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the peptidase A8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53351">
        <property type="protein sequence ID" value="PHX53351"/>
        <property type="gene ID" value="CP500_021945"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00077">
        <property type="entry name" value="lspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00855">
        <property type="entry name" value="SPASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="171" mass="19165" checksum="2C8F0F32D12CDD60" modified="2018-01-31" version="1">MRLKKNPWFWVAAIISLVLDHLTKFWVVQNFELTVPPQTQPLLPGVFHFTYVVNTGAAFSLFSNGGAIWLRWLSLGVSIGLMILAWFGPRINRWEQAGYGLILGGALGNGIDRFVSGHVVDFLDFRIISFPIFNLADVFINAGIICLLIATFHSPPPPRKQNNRDSISDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV18</accession>
    <name>A0A2G4EV18_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribonuclease HII</fullName>
            <shortName evidence="11">RNase HII</shortName>
            <ecNumber evidence="11">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rnhB</name>
        <name evidence="14" type="ORF">CP500_022070</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 12">Belongs to the RNase HII family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000213">
        <property type="protein sequence ID" value="PHX53328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53328">
        <property type="protein sequence ID" value="PHX53328"/>
        <property type="gene ID" value="CP500_022070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="3"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX53328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="187" mass="20485" checksum="8FF4ED944B535B5C" modified="2018-01-31" version="1">MIAGVDEVGRGALFGPVVAAACILPIELLDELANWGVRDSKQLTAANRSRLAVKIRAVAIDCQIGVASVQEIDRLNILQASLLAMKRAILKLKVTPDLCLVDGNQRIPNLAIEQETMVKGDSRSIQIAAASIVAKVWRDELIVRLAVKYPEYDLTNNKGYGTAKHKMGLERYGVSVFHRMSFSPCQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV46</accession>
    <name>A0A2G4EV46_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mg-protoporphyrin IX chelatase</fullName>
            <ecNumber evidence="6">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">bchI</name>
        <name evidence="9" type="ORF">CP500_021710</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Involved in chlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H2O + Mg(2+) + protoporphyrin IX = ADP + 3 H(+) + Mg-protoporphyrin IX + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60492"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.6.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the Mg-chelatase subunits D/I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53413">
        <property type="protein sequence ID" value="PHX53413"/>
        <property type="gene ID" value="CP500_021710"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00668"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011775">
        <property type="entry name" value="Mg_chelatase_ATPase-isu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02030">
        <property type="entry name" value="BchI-ChlI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="37"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="362" mass="40159" checksum="60F8EF8ACF97E10F" modified="2018-01-31" version="1">MPTVTATPARRAVFPFTAIVGQEEMKLALLLNVIDPKIGGVMIMGDRGTGKSTTIRALADLLPEIEVVAGDPFNSHPTDPDLMSDEVRDSLWDSSASRTLAQTDIKIARKKVQMVDLPLGATEDRVCGTIDIEKALSEGVKAFEPGLLAKANRGILYVDEVNLLDDHLVDVLLDSAASGWNTVEREGISIRHPAKFILIGSGNPEEGELRPQLLDRFGMHAEIRTVKDPNLRVEIVEQRSSFDQNPADFLSKYQHEQDDMQEKLVEAQERLKSVKLDRDLRVKISQVCAELDVDGLRGDLVTNRAAKALTALECRTEVTVDDIRRVMTLCLRHRLRKDPLESIDSGSKVTKVFDRVFGLETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV55</accession>
    <name>A0A2G4EV55_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_021605</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000201">
        <property type="protein sequence ID" value="PHX53414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53414">
        <property type="protein sequence ID" value="PHX53414"/>
        <property type="gene ID" value="CP500_021605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="23"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="356"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="390"/>
            <end position="397"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="667" mass="74004" checksum="6A92D8FADBA407E9" modified="2018-01-31" version="1">MSANKLLLKFARRYPGRILSTVLLGFSGALFNGISTTLIVPVLLNFLQEAIELRGAPPLIKTLMYPFEGMPQNQRLLLMTAAIVLAIILKNIAGYVNTLVATSLTRSLTFDLREAGLRLLLEVDLDFYSKTKVGDLINRLGGEVSRTAGAVGTAIGMFTASITVLVFVGLLLSISWKLTVIATILLGLVAWANQYIINRSKYFGNLLSEMSKDYSVRVLETMTGIRLVKSTGNEEREYQRIKNLIQRREQADFQAQVNYAAIAPINEVVNLIVIILIVFIGRTIFANKIESISTVLLTYLLILFRLIPLISQLNGGRSQFANTSASVEVVNDFLNCDDKPFMPNGSVPYTYLRSGIHFNKISFNYPNHKKLVLQGVDLFLPHGTTLALVGSAGSGKSTLADLLSRFYDPTVGNISIDGIDLRDFDIKSFRKAMGIVSQDTFLFNASVRDNIAYARPQATEAEIVEAAKGANAYEFIEQLSEGLDTRIGDRGVMLSGGQRQRISIARALLQNPEILILDEATSSLDTVSERYVQEAIEKLSCDRTTLVIAHRLSTVQKADKIAVIDGGNVLEIGSHEELLAKGGYYARLYSAQFAQETARDEALIKGSYEIRTRLTPMISYLKLLVDEMVDSPEERDELIIESYHSAANILKSLEFMENTIKRQYFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVD3</accession>
    <name>A0A2G4EVD3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_021490</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53438">
        <property type="protein sequence ID" value="PHX53438"/>
        <property type="gene ID" value="CP500_021490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="71"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="293" mass="32914" checksum="3DD1EA4987FE020C" modified="2018-01-31" version="1">MSFSFLRRYSTPYLFLFPALFVLSLTVLWPALQAFYLSFTSYEYDLTQAPQWVGLKNFERLWTDRTFWQTLTNTLLYLTCVVPVLVVIPLGMAILCNQKLRGMNWFRAAYYTPAVISMVVAGIAWKWLFAENGLLNLLGQMFGLPAVSWLADPKLAIFSVMAVTIWKGLGYYMVIYLAGLQAIPAELYEAAAIDGSDGLGKHWDITVPLMKPYLVLVAVISAISATKVFEEVYIMTQGGPRNSSKTVVYYLYERAFKDLEIGYACTIGLVLFLLILGLSILQVSIQGLAHKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVE9</accession>
    <name>A0A2G4EVE9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000186">
        <property type="protein sequence ID" value="PHX53513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53513">
        <property type="protein sequence ID" value="PHX53513"/>
        <property type="gene ID" value="CP500_021135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="242" mass="24355" checksum="7340A17655D2B84C" modified="2018-01-31" version="1" fragment="single">MTIKRQGIYLVGEDTADNVALEVGQLQDLPGGLVTGKGNDTVSGSSDAEVVYGGKGNDEIDGGGGNDYLRGDKDKDTVIGGDGDDCLYGGQGNDSIVGGSGNDSLYGDLGIDTLTGGDGNDTFFVLLDDEIIDYITDYQNGSDRIASENGILNFDNFTFSAGTGANGASSSDTVIIDKSSNRAIAVLLNVASSTFAGSPTPTPAPTPTPAPTPTPAPTPTPAPAPTPAPTPVTTPTPAPTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVI9</accession>
    <name>A0A2G4EVI9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000179">
        <property type="protein sequence ID" value="PHX53551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53551">
        <property type="protein sequence ID" value="PHX53551"/>
        <property type="gene ID" value="CP500_020915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="258" mass="27497" checksum="4A5590156E955063" modified="2018-01-31" version="1">MKLLDKVAVITGGGSGIGRAAAILMAKEGAKVAIIDRILDTGQETVRQLVNEGGCGLAVVADVGDVKQMRQAFQTIVDKYQRIDILFVNAGINGVWSPIEDLEPDEWDRTINTNLRGTFLTVKYAVPYLKKQGGSIVITSSINGTRSFRKVGATAYACTKAAQVTFAKMLALELAASKIRVNVICPGGVLTGIEQSAIKRNLDRIPGSMDFIHDLIPLTNNTAGSSEEVAQLVLFLVSDASIFITGTEVWIDGGGSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVK9</accession>
    <name>A0A2G4EVK9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021205</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000189">
        <property type="protein sequence ID" value="PHX53496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53496">
        <property type="protein sequence ID" value="PHX53496"/>
        <property type="gene ID" value="CP500_021205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037919">
        <property type="entry name" value="OGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366">
        <property type="entry name" value="PTHR44366"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="23"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="19"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="452"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="486"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="520"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="604"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="638"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="672"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="708"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="907"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="941"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="975"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1011"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1045"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1132"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1166"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1200"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1270"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1304"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1338"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1372"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1436" mass="162294" checksum="06D669EAAE14E416" modified="2018-01-31" version="1" fragment="single">QQIAQPHWFTLSTINPPCLPPLAKGGDWNLESDSPLPHPKSECQGLDCQRCLKRIFRQFEPIHLGDGVFSCSPQTETAIDSPETFVAKLPNGKAWVVPQKNSWMICNAIAIIDQDNQLLPELSREYPGELPGCENQHSTQHRFLNLEPEELPPLEHIDGTVAVLAGLSGNVYFHWMVDILPRVEILLSSGVNLEEIDWFLVNSYQQPFQRETLKALGIPESKIIECDRHPYIQAKQLIVPSFPGYLGWLSPRGLKFLRQFFLHDFSHKHDLDNYTKNTVPTRIDRSERIYISRSKCSYRRVINEENVIEILSEFGFVSVLLESMDLDEQIALFASAKVIVAPHGSGLTNIMFCQPGTKVIELMPPNYIRHYYWAISHQLNLEHYYVTGESFNCYQIRELMYQNPLTEDILVNLKSLKKIMGEINLLASNQALNLTLLKNHKNHTQIMNQESADYFQKRAEFYLEQGKLDDAVAACEQALKQKPDFAPAYKTLGKASQVQGNLAKAKHWYSKALEIQPDYAEIYTNLATLYTQEKDWERALSCYQKATSMQVENPKITNSERTDLTLDIDDIEVYIQGAEAFYSQRKFEQAAVACQRVIKVKPDARAYKICGNARQAQGKVEEAKNWYAKAIEIDPDFAEAYTNLGTLYAQEQQWQPAIACYQKAIALQPNLASTYRNLARVWTQIGQLSEADDCWFKAYSLEPAKATPEEHIHLGDNFLRQNYVTQAIRCYCHAIELNPNSNEAYQHLENALKSQKKLSAETANYRKIIKRPANIFGDLFKTVFLYLNGKSELLQISETRTSNPWQLGSTISDEKPNVQLQHSEPNDTVPEQLNAIALSENSSPIYQNLADVLSPVTVIESNLEPDSQKQEAADACIQQAESYYHQKQFDQALLECKRAIEIKADAVAAYKLCGKILQAQGNIEGAIECYKKTVKIKSNDAETHVNLGSLYAITQQWSAAITCYQQAIAIQPTLAPAYRNLARVWTQAGKLEEANECWYEAYSLEAEKVPADQHFKLGNNLFKQGQITHAIVCYRRAIELNPNLAGAYQNMGKALKQQGKLDEAALCFQRVAELKKPSLLNQDESGNSLAVAQVNTTSNGHVKSAEIATLSAPVKGNSNDRKPAQIVPAQDAETYIKQAESYYSEQKYEEAIAECKRAIEMKPEAALAYKILGNATQASGKLDAAWYWYTQALEIDPNFAEVHANLGSLYAQQKQWKKSISCYRKAIEINPNLASAYRNLAKVFLQSGKPKLGANCWYEALTLDINWATAEEHFTLGNTLLDMGKLDRAISCYQRAIQLQPNYANAYHNLGEVLSVQGKWEEAIATYRQAIEFNPNFEGSHYSLGKALASLNRGEEAIACYRRAIELNPNLAQAYHSLGDVLDSWGRLDEAIECYEKTIELKPDIWEIHHKLGDALQEKGEIDQAIEAYNRAIELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVL0</accession>
    <name>A0A2G4EVL0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type II toxin-antitoxin system HicA family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_020790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HicA mRNA interferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53582">
        <property type="protein sequence ID" value="PHX53582"/>
        <property type="gene ID" value="CP500_020790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038570">
        <property type="entry name" value="HicA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8462" checksum="A4C0C1BA95275B43" modified="2018-01-31" version="1">MPPLKPIKRRDLIYYLKQLGFDGPYSGKRHHFMLKDNLRITIPNPHQGDISANFLAKILRQAKVEMSDWDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVP9</accession>
    <name>A0A2G4EVP9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000173">
        <property type="protein sequence ID" value="PHX53613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53613">
        <property type="protein sequence ID" value="PHX53613"/>
        <property type="gene ID" value="CP500_020585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="17"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="119"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="21628" checksum="3EF533018734944E" modified="2018-01-31" version="1">MVNQSKLVSTKELQSEVSRLSEELQMRDQLVQQLSQELFRLVKGNTSFVPAPEVSDRHQAQMQAMREQLQAVEEQVGFYQEQITERDTEVYQLRQSVQELTDRSRMLEQVVQELPGVYRQKFAERIEPIKEKLDQLQKENRQLHTELQSVTYRLAVRSRKAKGLDLPAVDPDDNRGGIQMPSFGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVW4</accession>
    <name>A0A2G4EVW4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000166">
        <property type="protein sequence ID" value="PHX53659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53659">
        <property type="protein sequence ID" value="PHX53659"/>
        <property type="gene ID" value="CP500_020325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="22519" checksum="14ACCF22CE9A4521" modified="2018-01-31" version="1">MQLLDILSNLPTIESERLLLRKITLNDASDMFEYGSDPQVSEYTTWSTHTSIEDTKYFIKSLVKMYKKRELVDWGIIHKAEKKFIGTCGYVGWSMTHSRAEMGYALSRKYWNQGYMSEAVNAMMEFGFREMHLNRIEAKCQVNNIASARVMEKVGMQLEGILRQQLFVKDEYWDIKIYSILRDDFFADRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVW6</accession>
    <name>A0A2G4EVW6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000162">
        <property type="protein sequence ID" value="PHX53685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53685">
        <property type="protein sequence ID" value="PHX53685"/>
        <property type="gene ID" value="CP500_020130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="6676" checksum="E4DB02743909129B" modified="2018-01-31" version="1">MSQKNQAPAVILSLMMTIAIVGTGLWWFASRIGANLPTPPPPTRTLPNAPTPKPASSIDFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVZ4</accession>
    <name>A0A2G4EVZ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Heme-copper oxidase subunit III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_020150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000162">
        <property type="protein sequence ID" value="PHX53689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53689">
        <property type="protein sequence ID" value="PHX53689"/>
        <property type="gene ID" value="CP500_020150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="8">
        <location>
            <begin position="38"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="213" mass="23744" checksum="CAAB3C845D1FE1CA" modified="2018-01-31" version="1">MQGSTIDSPESVLDSSVAPVAAASAIEHHEEHEDLRLFGLVTFLISESLMFGGLFAAYLLLRGGAEAWPPEGTEVELLLPTINTIILVSSSFVIHFGDSAVKKNDIKGMRLWYAITAVMGIVFLGGQVYEYMTLGYGLTENVFANCFYVMTGFHGLHVFIGVSMILGVLWRSRREGHYSSVKHTGIEMAEIYWHFVDIIWIVLFLLIYVLTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW00</accession>
    <name>A0A2G4EW00_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000169">
        <property type="protein sequence ID" value="PHX53636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53636">
        <property type="protein sequence ID" value="PHX53636"/>
        <property type="gene ID" value="CP500_020450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8671" checksum="C21F5EC01A564493" modified="2018-01-31" version="1">MNYPIPTNLQEMMALRQHPLNEELVATAIAGVVQIARSQSQSLDELKAEVLADDNLLDLSQRIWLSDIVTQAWENLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW62</accession>
    <name>A0A2G4EW62_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c oxidase subunit 1</fullName>
            <ecNumber evidence="8">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ctaD</name>
        <name evidence="10" type="ORF">CP500_020155</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000162">
        <property type="protein sequence ID" value="PHX53690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53690">
        <property type="protein sequence ID" value="PHX53690"/>
        <property type="gene ID" value="CP500_020155"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014241">
        <property type="entry name" value="Cyt_c_oxidase_su1_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02891">
        <property type="entry name" value="CtaD_CoxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="9">
        <location>
            <begin position="22"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="584" mass="64876" checksum="765D56AC4D32C7A1" modified="2018-01-31" version="1">MAQAQLPVNTPPKIQGDTYSHHPTAWKWYDYFTFNVDHKVIGIQYLVTAFIFYLIGGLMAMAMRAELYTPDSDFLDPNLYNAFLTNHGTIMIFLWIVPAAIGGFGNFLVPLMLGARDMAFPKLNAIAFWVNPPAGLILISSFFFGGAQSGWTSYPPLSVITANTAQSMWILSIVLAGTSSILGSLNFVVTILKMKVPSMKWDQLPLFCWSILATSVLALVSTPVLAVGLTLLLFDINFGTSFYKPDAGGNVIIYQHLFWFYSHPAVYLMILPIFGIMSEVIPVHARKPIFGYKAIAYSSLAICLVGLFVWVHHMFTSGTPPWMRMFFTVSTLIVAVPTGVKIFGWTATLWGGKIRYTSAMLFAIGLLMMFVFGGLTGVTLGTAPFDVHVHDSYYVVGHFHYVLFGGSVFGLYAGIYHWFPKITGRMYNETWGRIHFVLTFIGTNLTFLPMHQLGLQGMPRRIAMYDPQFESLNKICTYGSILLGFSVLPFFFNMIWSWMYGPKASSNPWEALTLEWTTASPPIIENWEVLPVVTHGPYDYGMNNFVPNIDHLGVLIPAGNQKPVAISQAASASDANKNGDDGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW79</accession>
    <name>A0A2G4EW79_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_019900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53728">
        <property type="protein sequence ID" value="PHX53728"/>
        <property type="gene ID" value="CP500_019900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="5">
        <location>
            <begin position="108"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="6">
        <location>
            <begin position="398"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="173"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="251"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="622" mass="67017" checksum="565F46D4764AF3AE" modified="2018-01-31" version="1">MIVSPKKETAQVKVEDTKSADTKAAETKITDKKTAQKQSPKKPAPKSKRWAIALVAAGLIAVPATMYIVNSKSKPKVDAIATMTVPVEAQNLTVRITSSGTVQPVQRVNLSPKGSGRIAELFVEQGDKVEAGQIIARMESRDVEAQLAQAIAREASVRAKLAKIQAGNRSEDIASAQARLDQAQASLAQLQAGSRVEEVAGARARLQQTQANLQKLRTGTRVEEVSQGRAKLAQAQARLADAQTGSSKQEIAQAQSQIDSSKAQAELTTKRVERNRSLVQEGALAQDKLDELIKENRTAQAKVIESQKRLEQLQENRLSQIQQLQAAVEVEQQGLKQLQNGTRSEEIAKSEAEVAEAKSKLAQVENGSRPEEIAKAEAAVAEAKSQFAVQENGSRPEEIAQAQAELAEVQAQVRYQEVQLEDTKVRAPFAGVITQRYAIQGAFVTPATSASEATSATSTSIVALARDVEVLAKVPEADISQIKPGQEVEIVADAYPDKVFKGKVKLIAPEAVKERDVTLFQVRVAIDTGKDLLQSGMNVDLRFVGQKLSNALVVPTVAIVTNKGQTGVLVPDEKQQPKFQAVTVGSTIGNKIQILEGAKAGDRVFTELPQGKKLEDIIKNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW85</accession>
    <name>A0A2G4EW85_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000154">
        <property type="protein sequence ID" value="PHX53789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53789">
        <property type="protein sequence ID" value="PHX53789"/>
        <property type="gene ID" value="CP500_019560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="106"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="20679" checksum="D7C49F6DDAA98FE5" modified="2018-01-31" version="1">MQGILVSLGVMLVCFVFLIVAQFSGSQEKAIATEPKISLPQTAIEILSDQSLNKNSLLVADATVPDVSPTIAENKMTENTDKIVTTTSGLKYVELVEGDGAIPKTGQTVVVHYTGTLEDGTKFDSSRDRNSPFKFSIGVGQVIKGWDEGVGTMKVGDRRKLIIPPDLGYGARGAGGVIPPNATLIFDVELLKIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWJ5</accession>
    <name>A0A2G4EWJ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_019320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000149">
        <property type="protein sequence ID" value="PHX53848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53848">
        <property type="protein sequence ID" value="PHX53848"/>
        <property type="gene ID" value="CP500_019320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005524">
        <property type="entry name" value="DUF318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03773">
        <property type="entry name" value="ArsP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="359" mass="38660" checksum="3CC41F71FFB7EED0" modified="2018-01-31" version="1">MQPALTNQLNNAFTLFLSLLVEAIPFLLLGVLFSGLLLGFIDDRKLIARIPRNPLLGALAGSLIGFLFPVCECGNVPVARRLLMQGVPAPVAIGFLLAAPTINPVVIWATWTAFRDQPEIVVLRVVFSLVTATIIGWVFSAQKDLRPLLQPSVARAIPLPKPELSEKELLKAETPSLLQSGTFMLGMPGGTVPIESLLQDNWKPLQTGQTAKSSKPSSMFHRVSKERLRLLLDTMVQELRELGGVLVIGSAIAAIIQVGTPRELILNLGQGPVSSILAMLLLAALVSICSTVDAFFALSFAATFTSGSLLAFLVFGPMFDLKGIGLMLSIFRGRAIIYLMVLAAQLTFLMTLAVNLYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWM0</accession>
    <name>A0A2G4EWM0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CO2 hydration protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53919">
        <property type="protein sequence ID" value="PHX53919"/>
        <property type="gene ID" value="CP500_018850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010220">
        <property type="entry name" value="CO2_hydration"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10216">
        <property type="entry name" value="ChpXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01964">
        <property type="entry name" value="chpXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="440" mass="51249" checksum="CA70E5874C67DB05" modified="2018-01-31" version="1">MVQTPNKPATKLPPSKHEFAEVIHRLEAGGAMIPDTPENLMQIIAIWKAYAVPMDFYWRDLLYIAERVFLQPLPFFKYFLPQEYLDLQNHYSSDGADLRIWRGTGSAHPELLEFMEKGETGKLPRLFHHLWHDRINMEFAEECMRSMLWHRGLYVPTNQFDPYLDSDEYKANADRAIKAYFKKDPFMLGLHKAFPEMFLEQCRQMSYYSNLGLFWEVMAPVFFEVSDLYDEGKVTTVPQAMDFLVNGIFAIAGRPIYHHVQIDGETYEIIPKSKGFTWLYEAALPYVESVFYRTSPFRGTKSYNAQAREVPDDQKDFHYGVLYADKFPVGTAGIPPTLLAQDMLHFLPPYLLDFYKGRCRGEDDILNQIGVTFQRSMYCVTSAVFQALRTALLYPLDDPNPKHLKANRAFFESQLDRFCRPEYGMKYAAKLNSIQTSDYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWP3</accession>
    <name>A0A2G4EWP3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_018680</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245907">
        <property type="entry name" value="M.Tbo703ORF18680P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53953">
        <property type="protein sequence ID" value="PHX53953"/>
        <property type="gene ID" value="CP500_018680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="372" mass="42012" checksum="4A15BE61BCF2BFD0" modified="2018-01-31" version="1">MKSEISRNAITWTQKPRLISLFSGCGGMDLPFHKAGFEVVWAIDSNKYACKTFSRNIADVIVNDSIENIDIAQVPDAEICIGGFPCQDFSMIWKRPGLEGTRGNLYTYFLDFVNKKQPKAFVAENVKGLLSANNHQAIKQIISDFESIAPGYLVKPKLYNFADYGVPQFRQRVLLVGIRMDTGFNFVHPQPEYGENRNNPYRSAGEALKDVEKVPFNNEHHKIQPRTIEILKRIKAGGNFTDIPKDSPYYVKGMISHVYRRIHPDKPCATIIAGGGGGTWGYHYPEPRSLTNRERARLQSFPDDFVFEGSITEVRRQIGNAVPPDGIVDVVESLIPLFKGNYPPVDLYNLNKKLQLMSIKERLEHAESEVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWR8</accession>
    <name>A0A2G4EWR8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000135">
        <property type="protein sequence ID" value="PHX53969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53969">
        <property type="protein sequence ID" value="PHX53969"/>
        <property type="gene ID" value="CP500_018660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="48"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="409" mass="45521" checksum="1BD7D491E264F39A" modified="2018-01-31" version="1">MILLTLLIFSLIVSTAYTKNLRRSVKNAPRTGRSPSQQSPIAQFPKVSVIVPAYNEAENIRDCAIAILESTRLSVDNLEVLIVDDRSTDDTLAIAQTLQQQLNDPRLKILAGQARPANQYWAGKNWACAEAVQVATGEFLLFIDADVRLKPEAIEAAIETVQTEKIDLLTCMPALVCECFAEWLVQPLMFNHLAVCFDFTAVNDPTTDSAFAAGPFMLFRRSAYDKIGGHEAVASEIVEDVELARRIKRGGLKLALYAGSNLAFVRMYRSWSALWEGWTKNLYLGANRSWGAMIYMAAIMLFLYPMPWLTLGILLANGEVANIITNYQLPITNYQLPITLLTIFLAVRVIWQQYTLRDLGAQISDCSTKYWWLGGLGGTLIAAIAIASAIKTETGWGWTWRGRALQIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWT3</accession>
    <name>A0A2G4EWT3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53926">
        <property type="protein sequence ID" value="PHX53926"/>
        <property type="gene ID" value="CP500_018890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7798" checksum="C4EA8F3951B7683D" modified="2018-01-31" version="1">MSETPKLPDPEVIQKTVRNLRGACLRLDALTLSLDELIAMVEADIRNSPINVHRRENAKRLAEYVKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWT9</accession>
    <name>A0A2G4EWT9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cobalt-precorrin-5B C(1)-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.195</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cobalt-precorrin-6A synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cbiD</name>
        <name evidence="7" type="ORF">CP500_018540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Co-precorrin-5B + S-adenosyl-L-methionine = Co-precorrin-6A + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:26285"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:60063"/>
            <dbReference type="ChEBI" id="CHEBI:60064"/>
            <dbReference type="EC" id="2.1.1.195"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 6/10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CbiD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.195" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53991">
        <property type="protein sequence ID" value="PHX53991"/>
        <property type="gene ID" value="CP500_018540"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00227"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043780">
        <property type="term" value="F:cobalt-precorrin-5B C1-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046140">
        <property type="term" value="P:corrin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00787">
        <property type="entry name" value="CbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002748">
        <property type="entry name" value="CbiD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036074">
        <property type="entry name" value="CbiD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35863">
        <property type="entry name" value="PTHR35863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01888">
        <property type="entry name" value="CbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026782">
        <property type="entry name" value="CbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111342">
        <property type="entry name" value="SSF111342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00312">
        <property type="entry name" value="cbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013579222" description="Cobalt-precorrin-5B C(1)-methyltransferase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="378" mass="40956" checksum="96DEB26661374F89" modified="2018-01-31" version="1">MTKTQPRSGYTLPVFACAAALAALRCCRGVHSIDSVSVDLLDPIITAEVPIEQVSLLKTGTALAVTRSEPGDNLDLTRHTPVWAMVELQRMEEAEIGEAQEQILIIGGEGIGHHKIGGGAAIYDYAQRLLRVNLSRELQKGEKMTVTLILPSGRQLATRTSNEAFGVVEGLSLLGTTGISQPLSAPGQLEIYREQLQQKATLFDCLVFCIGENGLDLARQLGINPQRLIKTANWLGPLLAEAGCQGVKSILLFGYHGKLMKLAAGIFHTHHHLADGRREILTAFCARAGMPADACSSIFEAATAEDALQQLRAVDVANQSNWVDRIYGDIAQQIDLRSSDCIFAHSGRRISVGSVMFGRDRQIIVKSEIGDTFLTQIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX51</accession>
    <name>A0A2G4EX51_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_017840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54125">
        <property type="protein sequence ID" value="PHX54125"/>
        <property type="gene ID" value="CP500_017840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="486" mass="55008" checksum="0806661D3124BA81" modified="2018-01-31" version="1">MQGKTLEGRYYIIKHLGGGGFGQTYLAEDQRRSGNLRCVVKQLKPQSTDPQTLEIARRLFKTETDTLHKLGTHKPIPELLDYFEENQEFYLVQELIEGRDLSKEITPGQRLSESEVMPILQEIIEILVFVQQDKVIHRDIKPANLMRRNSDGKIFLIDFGAVKQISTQIANNTGQSPPTIIIGTNGYMPAEQNNGHPNFTSDIYAVGMTGIEWLTGILPHELPKDVNGEIVWRDRTQVSDGFANILNKMVRYHFRDRYQSAAEVLQALNSLRRIPPSSTVVSSPNLLTLMSNWTRDHKIGLLGVGLAAIFGVAALFTPEIRKMVGLEAADNLASYDNTAQGIKIKYPDNWTKQEEYNAVTKEVVQFISPKESEGDKFQERLIVTVEPTTNNKTLDEYTKLSKQEILKLDKNAKIAQEGESTLAGKSGYRVVYTTKEGNQEFKKLNVWTMKNDKAYLITYEAEAGKYEQFLPVVEKMIKSLEVQDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX61</accession>
    <name>A0A2G4EX61_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000123">
        <property type="protein sequence ID" value="PHX54124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54124">
        <property type="protein sequence ID" value="PHX54124"/>
        <property type="gene ID" value="CP500_017835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="117" mass="13681" checksum="7A3A85ECBBBAE10A" modified="2018-01-31" version="1">MVTVSIKDEYVEVLSALGDLQTAMDLAIQRYTIEQITGKVAELRQRNAQYQAKYGMDYLSFNQRVSEDEVFIRNLESKVNNLWEIDLADWEFCYKGIGDWTRKLQNLLLETNNLISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXI1</accession>
    <name>A0A2G4EXI1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017225</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54245">
        <property type="protein sequence ID" value="PHX54245"/>
        <property type="gene ID" value="CP500_017225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039005">
        <property type="entry name" value="CSPG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51854">
        <property type="entry name" value="CSPG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="137"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="377"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="383"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1079" mass="108562" checksum="C395368DEFF6C387" modified="2018-01-31" version="1">MPSAVPLVPIPAPTPTPTPEPTPTPTPTPTPTPTPTPTPTPTPTPADDTFGGIDDTLGTGRSTTPAIIGGIIRGTDKNDSLVGSVGPDVISGLQGNDNLQGGEGDDLVFGNEDDDVLFGGPGNDVLDGGSGLDTLYGGKSSDSLDGGNNPDLLYGNDGSDTVVGGEGRDTGFGGKGSDSMRGGLGDDSMFGDRGDDVLWGDQGNDSLFGGDGEDLIFGNEGGDWLYGNSGADTIFAGDGDDIVFGGAGEDIIDGGAGNDVLWGEAGKDLVAGGEGKDVFVMGRFSSPGISGSTNPVFITSGGPDIGDADIFRDFRQGEDLIGLSGELKFEDLIIFQSTDAQAGSTIIRNGVSGDFLAVLPGVDSRTLGRASFVIGASVPGSATPLPAPTPSPTPTPTPSPTPTPTASPTPTPTASPTPTPTASPTPTPTASPTPTPTPTPTATPTPTPTPTPIVSLNQAPKAVNDNFTAVTGETLSLNVLLNDTDPDGNALTVTTFTATAKGQLTPLAGGTFQYTPNAGFSGADSFSYSISDGRGGTGQAIATINVSSPPKLAINDGLVVAKSVPIGTITAADLLIKDSDNTPSEIVYTITQAPSANKGFLQRSDTFLNVGSKFTQDDINNNIIKYNLLPTGGSDSFTFTASDGATKIGPTSFSITVVDNIVDRSNLPASSFTGSNLSDFIIGGPGNDTLLGADGNDIIDGRAGDDLEFGQAGNDSVLGFTGNDTIDGGFGNDTLDGEDGIDSLIGGVGNDLMFGGNDDDILLGGDGNDIMDGGGGNDSVQGEAGDDSIFGGIGNDNLFGGIGDDSFDGGAGDDFIDGGIGRDLLDGGINNDSLSGGDGEDTILGGEGNDTELGGAGNDYVLGEAGNDALLGEAGDDTIDGGAGSDSLSGGFGNDLMLGSNDNDSLSGGAGNDIIGGGAGSDLLTGDVGNDFFYYETPSEGVDIISDFNNGNGNDTFLFRSANFGGFTNSGTINDFTSFIVRNIGSGGDNISKQAVILFENKFDNAQAVNAVLKNQNGSSKTGAFFVYLNNTFNKYVLGFDPNAADDSLPAFDLAVLNSIPTVPGSLSTVITSSQFKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXI6</accession>
    <name>A0A2G4EXI6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000117">
        <property type="protein sequence ID" value="PHX54188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54188">
        <property type="protein sequence ID" value="PHX54188"/>
        <property type="gene ID" value="CP500_017520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039554">
        <property type="entry name" value="HigA2-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13744">
        <property type="entry name" value="HTH_37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_37" evidence="1">
        <location>
            <begin position="13"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="98" mass="10907" checksum="4184B5A11CF09B79" modified="2018-01-31" version="1">MTENTITQANDNIFLDLGFSAQEADNLLIRSQLMLALQNQIKHHGWTIDQTAQHLKQSSDQIKALTQGKIGQFSVDTLIIMLNQVGMTVKVEICPKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXL0</accession>
    <name>A0A2G4EXL0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gfo/Idh/MocA family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_017000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54269">
        <property type="protein sequence ID" value="PHX54269"/>
        <property type="gene ID" value="CP500_017000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="16"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="153"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="337" mass="37200" checksum="C6A30768CE9FDF48" modified="2018-01-31" version="1">MANIDIRSGFSVNSPIRVGIVGTGFAAKLRAEMLQTDARTHLVTVAGHTPHKTEAFCQTFGAEAAVSWRKLVERDDLDLVIVCTVNRDHGAIVLAALENDKHVVVEYPLSLDVSEGERAIALAKQKQKLLHIEHIELLGGLHQAIKASLPLVGKVFYTRYITITPQHPAPQRWTYQHSLFGFPLVGAISRLHRFTDLFGEVTSVNCQTLFWDTQPDFYKASLCNAQLHFANGVVAEAVYGKGETFWQSENVFTIYGEDGTLVFTPESGQLIQGENKRTIEVGTRRGLFAKDTDMVLEYLLNGTPLYVNNASSLYALKVADAARRSSQTGQNVALINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXM8</accession>
    <name>A0A2G4EXM8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000110">
        <property type="protein sequence ID" value="PHX54294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54294">
        <property type="protein sequence ID" value="PHX54294"/>
        <property type="gene ID" value="CP500_016940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="79"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="281" mass="31528" checksum="91E7E21F9CB6C1A8" modified="2018-01-31" version="1">MANWNRKNIKRLLFGEFSWKRLMRSIIFIYAFLCFYACFFSEGLIFQSPPSSQSDSREVIKVGSANGMKISAVHFPNPQAKYTILYSHGNAESLDGILWVLREIRDSGFAVFAYDYQGYGTSQGKPSEYNTYRDIDAAYNYLTQQLGVPAKQIIVYGRSVGGGPAIDLASRQSVGGLVVESSFVSVFRVLTRIPILPFDKFVNIDKIGKVRSPVLVIHGKADDVVRFWHGERLFVAAKEPKLNFWVDGAGHNDLMDVAGDRYAATLRKFAKLVDESSLPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXN9</accession>
    <name>A0A2G4EXN9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54246">
        <property type="protein sequence ID" value="PHX54246"/>
        <property type="gene ID" value="CP500_017195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="101"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="177" mass="20215" checksum="DC3293E3E9293105" modified="2018-01-31" version="1">MHSEEIPTQEIIDKLRQALEPRMGIAEPLLSGSEKRAIAFDEEDEDIALLKTGFDIYNVPITSYQRRLGSVVIAVRKIVRKLLKPVLERQVIYNFANTRVVQTLSNQLQKLQQNQQTLEKKIKSEFSNQSPEVTAKIMVQQAAITALQSEIEQIKAVQQQHTAMLEEITAQLFDRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXW8</accession>
    <name>A0A2G4EXW8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1624 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54007">
        <property type="protein sequence ID" value="PHX54007"/>
        <property type="gene ID" value="CP500_018380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012429">
        <property type="entry name" value="HGSNAT_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07786">
        <property type="entry name" value="HGSNAT_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="HGSNAT_cat" evidence="2">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="377" mass="42043" checksum="05D243CFE5EAA6DF" modified="2018-01-31" version="1">MRLKSLDVFRGIAIASMILVNNPGSWKQVYPVLEHAEWHGCTPTDLVFPFFLFIVGCAMSFSLSKYTETTTKIETNIYWRIARRAAILFILGLLLNTSSIALDVLLNSAPLENFGKIRIMGVLQRIGLAYLISAIAILNLSPRNQKLLAIALLIGYWSALTVFAVGGYSTSALTPEGNFGGYVDRIILGSQHLYKGGPFDPEGLFSTLPAVVTVLTGYFTGEWLRVQQIKTRTSVNLAICGLCCLVIGHLWGFIFPINKQLWTSSYVVFTAGWALLLLAVCYETIEVRGWKWGRPFEIMGLNAIFVFVASGIVARILLKTHIGSGKSAPSTYTWIYENWFLPWAGPLNGSLAFAVTAVLFWWLILYGMYRRGWEIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYI3</accession>
    <name>A0A2G4EYI3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54571">
        <property type="protein sequence ID" value="PHX54571"/>
        <property type="gene ID" value="CP500_015415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="13216" checksum="B490246FCBB1A534" modified="2018-01-31" version="1">MEKLTQYRSIAREVIDEYARYKPSLGQSDMSAVYDIDRDHYLLVSFGWNGDRRVYSTILHLRIFEGKLWIERDETEEGVTQDLLDRGVFQKDIVLAFYHYEDRKLTDFAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYL1</accession>
    <name>A0A2G4EYL1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Uroporphyrinogen decarboxylase</fullName>
            <shortName evidence="8">UPD</shortName>
            <shortName evidence="8">URO-D</shortName>
            <ecNumber evidence="4 8 9">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemE</name>
        <name evidence="13" type="ORF">CP500_015145</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8 9">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 8 9"/>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54612">
        <property type="protein sequence ID" value="PHX54612"/>
        <property type="gene ID" value="CP500_015145"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8 9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="11">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="12">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="28"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX54612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="354" mass="39269" checksum="31214ED9892C91F5" modified="2018-01-31" version="1">MSALNEVPLLLRAARGETLERPPVWMMRQAGRYMKAYRDLREKYPSFRERSEIPEVAIQVSLQPWHAFQPDGVILFSDIVTPMPGLGIDMDIAEGKGPIIHSPIRTQQQIDALQPLNPEESLPFIKEILQSLRQEVGNKSTVLGFVGAPWTLAAYAVEGKGSKDYAIIKNMAFSDPTLLHQLLSKFADAIAVYVRYQIDCGAQVVQMFDSWAGQLSPQDYDTFALPYQKQVFDQVKKTHPDTPLILLVTGSGGLLERMATSGADIVSVDWTVDMADARRRLGPNMNVQGNLDPGVLFGSQAFIRDRILDTIRKAGPRGHILNLGHGVLPGTPEDNVRFFFETAKQADKLLAVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYM8</accession>
    <name>A0A2G4EYM8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysozyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_015040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54635">
        <property type="protein sequence ID" value="PHX54635"/>
        <property type="gene ID" value="CP500_015040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043215">
        <property type="term" value="P:daunorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900753">
        <property type="term" value="P:doxorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005894">
        <property type="entry name" value="DrrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01188">
        <property type="entry name" value="drrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="340" mass="36970" checksum="653A0B2AB96D8245" modified="2018-01-31" version="1">MAPAVLIENLQKRYGNVEAVKDVSFKVEPGEIFGLLGPNGAGKTTTLRVLCTLSAPDSGRIEVSGISAVSQARIARQRLGYVAQEVALDKVLTGRELLQLQAALYHLPRKTIKGRIDEMVKLLGLEEWENKKTGTYSGGIRKRLDLAAGLLHQPDVLVLDEPTVGLDIESRVVVWDFLRRLRDEGTTVLITSHYLEEVDALADRVAIIDKGTVIAEGTPLELKNRVGGDRVTLRIREFSPIEEAETAKTLMESLSFVQEVIVNAAQGNSLNLVVTPQSDALVTIQQALKNAGLPTFGIAQSRPSLDDVYLAATGKTLLDAELAAASNRDLKAEQKQAMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYU3</accession>
    <name>A0A2G4EYU3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycolate oxidase subunit GlcD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">glcD</name>
        <name evidence="2" type="ORF">CP500_014830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54689">
        <property type="protein sequence ID" value="PHX54689"/>
        <property type="gene ID" value="CP500_014830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009339">
        <property type="term" value="C:glycolate oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003973">
        <property type="term" value="F:(S)-2-hydroxy-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004490">
        <property type="entry name" value="GlcD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00387">
        <property type="entry name" value="glcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="44"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="491" mass="52726" checksum="7AABDACBAC0825E3" modified="2018-01-31" version="1">MIAIETERNWKPVIKEFEAVVGKNGVVQRREELLVYECDGLASYRQRPALVVLPRTTEEVAKVVKICDRNSIPWVARGAGTGLSGGALPVENCVLIVTALMRKILKVDLENQQVVVQPGVINNWVTQAVSGAGFYYAPDPSSQIVCSIGGNVAENSGGVHCLKYGVTTNHVLGLKLVLPDGSIVDVGGEIPEMPGYDLTGVFVGSEGTLGIATEVTLRILKAPESICVLLADFASIEAAGESVSDIISAGIIPGGMEIMDNISINAVEDVVATGCYPRDAAAILLIEIDGLEVEVATNKQRISEICKQNGARNITTAHDPETRMKIWKGRKAAFAAAGHLSPDYYVQDGVIPRTQMAFVLKEIEGLSEKYGYQIANVFHAGDGNLHPLILYDNSVEGALEKVEELGGEILKLCVKVGGSLSGEHGIGADKKCFMPDMFSEVDLETMQWVREVFNPKGLANPGKMFPTPKTCGEAARAKMETVNKLEGVELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ01</accession>
    <name>A0A2G4EZ01_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54744">
        <property type="protein sequence ID" value="PHX54744"/>
        <property type="gene ID" value="CP500_014480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="808"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="837" mass="92248" checksum="D289DF1125D7F988" modified="2018-01-31" version="1">MNSQKYKIQALIAEIDEVLSKPVPRLPWTGSIDLVHQRQLLERVRTYLVLPDSKLVVAHKQANSPKSPPPPVPVPKVPLATTNQQSATEQILQAVTGEICHLRESLTGPLEADIQALREEQQALVQEIKLLEVKRQQQQSLAQQQANQQQIISEFLQAVTSRLQETLVADVSPSQASNLDNQYAASASDSLEGNQQTVEHLRMTSAERLEAMQRFEAEADRLLMRLDSTMNIVFEALQENLETYQGSLSQGLERMHGLGQQSEMMFTALVNHLAQELGREASSYVQQPTILSNLESATLTSQMVSNTAQIELSGETPMAEGALADGSNETFQEQERFPYAGTELSPQFGELRRDRTPAAISLPDLEENLFGSAPQSDRPTTAFPGTQSEPESAQTDEDIEELRRDRTFAAISLPDLEENLFGSAPQSDRPTTAFPGHESEPESAQTDEDLEDVYANLFLGEEVAELDLEDFIIENTATATEIELVRSETQPVNASYESLNNSEDLFSNLVDEEELVHQNQEVVETNEPINGTFTLFQNLLDEDDSVEDYRVNENLEFGIANSVEELTLDTPDLVKQEEVVKLALFPQPTAPMVEPQIDADDRENAENTPKGREISDTSAGDQTLAAPPSLSRTAEISSTSQNLPPQNQTERSASTSSNVAPGDVYIQASPDENLLPVEQENEEDVDRSLNLDNDILEQLESDLYSLEGLPNSSSLRSQPSATLNSGFLVDASDSGAENPFAKLAEEELGTLEDLFPDMLELSSEDEIDEILTLEDELDVELLAQEEDENVSLDDILASLIEADQASAQISGDTQKLGSNSPESQKKNTLSRSPVKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ05</accession>
    <name>A0A2G4EZ05_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="8">S12 MTTase</shortName>
            <shortName evidence="8">S12 methylthiotransferase</shortName>
            <ecNumber evidence="8">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">rimO</name>
        <name evidence="12" type="ORF">CP500_014550</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="8">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54726">
        <property type="protein sequence ID" value="PHX54726"/>
        <property type="gene ID" value="CP500_014550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="12" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="10">
        <location>
            <begin position="5"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="140"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="9">
        <location>
            <begin position="372"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX54726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="438" mass="48644" checksum="874937A6B0D66A18" modified="2018-01-31" version="1">MATKPTIAFTHLGCEKNRIDTEHMIGLLAQAGYEVDSNEELADYVVVNTCSFIQAAREESVRTLVELAEANKKVVITGCMAQHFQQQLLDELPEAVAIVGTGDYHKIVDVMQRVEKGDRVSLVSSEPTYIADETTPRYRTTSEGVAYLRIAEGCDYRCAFCIIPHLRGNQRSRTIESIVAEAKQLASEGVKEIILISQITTNYGKDIYGEPKLAELLRALGKVDVPWIRMHYAYPTGLTPQVVEAIRETPNVLPYLDLPLQHSHPEVLRAMNRPFQAGINDAIVDRLKAAIPGAVMRTTFIVGFPGETDEHAAHLLEFVKRHEFDHVGVFTFSAEEGTPAYSLPNQLPAEKMEIWRNSVMAAQQPISLKKNQESVGQVVDVLIEQEQPETGELIGRSARFSPEVDGLVYVTGEARLGSIVSVKITRADVYDLYGQVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ66</accession>
    <name>A0A2G4EZ66_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54814">
        <property type="protein sequence ID" value="PHX54814"/>
        <property type="gene ID" value="CP500_014205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="7416" checksum="E5E03DF0EDC7601A" modified="2018-01-31" version="1">MSTENQARSLMMRHHHLVKNRQQSMLNRTATEVGMEDPTYWGHIQGKPQPSLKDSYDRSNATMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ72</accession>
    <name>A0A2G4EZ72_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54825">
        <property type="protein sequence ID" value="PHX54825"/>
        <property type="gene ID" value="CP500_013935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="251" mass="29850" checksum="B35F9ADD257A8123" modified="2018-01-31" version="1">MNFYFVFEGKTEPIVYKKWLSVLVPDLTEVDSFDAVNQNNYYYESDMGVPSCYRVAANAIQEINDCPKYNYLVLFTDADRFTVAEKKAEAYEQIKSELKDKPFKTLPKNCKLEIIVQKVCIETWFLGNRKFFVRNPQHNEILKQYIEYFDVRLSNPEDLASEFVQDEENTKEIFGYKTKALFHESYLREIFKERSSASNKHFSYSKPRPREVQEKYYLEQLIARIEANSDHLLSFQEFIEFCLKIKGQQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZE6</accession>
    <name>A0A2G4EZE6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54883">
        <property type="protein sequence ID" value="PHX54883"/>
        <property type="gene ID" value="CP500_013690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="23"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="382" mass="43554" checksum="0FC815A11E8C91B0" modified="2018-01-31" version="1">MKHLDNLTIHRFRGLRDLTLQDLGQINLLVGGNNSGKTSVLEAISTYCRPLDIGEWLKTAERREIKASPTLPLNAFKWLFPQNNEVPKPILYVGETYLSGSGSFQVIESRAIYNEMELLYRSEKDIEDSAEDWVEYYDDIEYKSSHGAEIELKAIFRDPPAGDARVLGREFSEKIELWSNQRLSRHDSENNHFYPQLPIDMVTPVSHRQEKLESYLLSQAILRGLKNEVIKLLQIVDGEIIDLEILSVGEPRPSIYINHKLLGFSPLSAFGDGVRRLLFIALAMAKVRGGVLLIDEIETAIHTEALGSSFAWIVQCCKLMDVQLFATTHSLEAIDSMLDASNIDTDLVLYRLEKQESQTQAVRIERERLQRLREDLGQEVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZM7</accession>
    <name>A0A2G4EZM7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54960">
        <property type="protein sequence ID" value="PHX54960"/>
        <property type="gene ID" value="CP500_013120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="329" mass="35888" checksum="8F56AC4636012EE9" modified="2018-01-31" version="1">MANYAIFDEQYYLASYPWLKPAIDAGIIKSGREHFEKFGQAGGLTKVSRYFDEATYLSVNTDLRPFVRTVNPNAPFATGLDHFIQFGYEEGQRRSAASPEYSEDFYLANNSELRSFVGPNAAFKSGYQHFIQFGAKEGRFGTSFFEPEYLKENPDIVPFVNSGTLKTGREHYFNFGKNEPNRSATFVGSRSNDIITGVGVGSTELIGVEVGIDPQRNRQYESFGTNEFDVLIGSPGVDTFVLGVPATTGNVTPTPLYLGNGQATIRNFNVDDDFVQLQGTSLDSYQLVPVGSNLSIQTRFGDVLGVIEGGAGLGLIAQGTNGNGTFLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZN1</accession>
    <name>A0A2G4EZN1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">DNA-directed RNA polymerase subunit omega</fullName>
            <shortName evidence="10">RNAP omega subunit</shortName>
            <ecNumber evidence="2 10">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">RNA polymerase omega subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 10">Transcriptase subunit omega</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpoZ</name>
        <name evidence="11" type="ORF">CP500_013160</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the RNA polymerase subunit omega family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 10"/>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54966">
        <property type="protein sequence ID" value="PHX54966"/>
        <property type="gene ID" value="CP500_013160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00366">
        <property type="entry name" value="RNApol_bact_RpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003716">
        <property type="entry name" value="DNA-dir_RNA_pol_omega"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
        <property type="entry name" value="SSF63562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 11" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="9086" checksum="96D51B0CD5CB8EB1" modified="2018-01-31" version="1">MAKRPPFDSTQLTRRAEELISAASNRYRITVQVANRAKRRRYEDFDNNMDDHQMKPVMRAIFEMSDELTQPEIIGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZR1</accession>
    <name>A0A2G4EZR1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Oligopeptidase A</fullName>
            <ecNumber evidence="8">3.4.24.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_013275</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-|-Gly-Pro-Ala is cleaved, but not Z-(Gly)(5).</text>
            <dbReference type="EC" id="3.4.24.70"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.70" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54988">
        <property type="protein sequence ID" value="PHX54988"/>
        <property type="gene ID" value="CP500_013275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045666">
        <property type="entry name" value="OpdA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19310">
        <property type="entry name" value="TOP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TOP_N" evidence="11">
        <location>
            <begin position="33"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="10">
        <location>
            <begin position="235"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX54988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="697" mass="77019" checksum="037B456BE33CFBBF" modified="2018-01-31" version="1">MTATVTITQNPLLIGKGLPPFEAIAPEHIVPAIAHLLTELEAELATLEVSVQPTWSGLVEPLQELGDRLNWTWGIIGHLMGVKNSPELRSAHETVQPQVVQFGSKLSQSKPLYQAFKALRASENWDSLDSAQQRIVEAALRDAELSGVGLEGEEKERFNAIQLELAEATTLFSNHVLDATKAFSLTLTNKDEIDGLPPSLLSLAAQVARSAGAENADAQNGPWRITLDFPSYAPFMQHSTRSDLREKLYKAFISRASSGELNNWPLTDRILALRQEQAALLGFSSYADLSLASKMAPNVAAVEALLEELRLASYSAAVKDLAELKAFAAEKGAAEAGDLKHWDIGFWSERQREEKFAFSAEELRPYFALPQVLEGLFGLVKRLFGVTVIAADGQAPLWHEDVRYFQINDESGNAIAYFYLDAYSRPEEKRGGAWMSECVVRAKFVEAGVTKTRLPVAYLTCNQSPPVDGKPSLMTFLEVETLFHEFGHGLQHMLTNVDYAGASGINNVEWDAVELPSQFMENWCYDRATLFGMAKHYETGETLPEHYYQKLLASRHYMSGSVMLRQVHFSRVDIELHHNYQSGGSETVADVRNRIAETTTVLPPLAEDAFLCAFGHIFAGGYAAGYYSYKWAEVLSADAFAAFEEAGLEDERAIASTGQLFRDTVLGLGGSLHPMEVFKTFRGREPSTKALLKHSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZU9</accession>
    <name>A0A2G4EZU9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA/RhaT family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55033">
        <property type="protein sequence ID" value="PHX55033"/>
        <property type="gene ID" value="CP500_012760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="14"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="173"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="357" mass="38602" checksum="EE2F527D34B11521" modified="2018-01-31" version="1">MQLKLTDSKLPFAPLLLIAPFFLWGTAMVAMKGVMPHTTPLFVAVVRLMPAGVLVLIAAAFMGKAQPQSWKAWLWISLFALVDGTLFQGFLAEGLARTGAGLGSVMIDSQPLAVAILCLWLFQEKIGFWGWLGLVIGVIGISLIGLPDSWILGLFHPENVQVSADVGQLFEGGEWLMLLAALSMAVGTVLVRWVCRYVDPVVATGWHMILGGLPLLGISAATESDQFVNIDFSGWMALGYSTVFGSAIAYGLFFYFASSGSLTSLSSLTFLTPVFALLFGNLFLGEVLNPLQSMGVGLTLVSIYLINQRDTLTQKLQKVRHREASAEEEATGLLESSELNSVELPVQVRVTELESEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F014</accession>
    <name>A0A2G4F014_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Potassium channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55078">
        <property type="protein sequence ID" value="PHX55078"/>
        <property type="gene ID" value="CP500_012710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0407">Ion channel</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="2">
        <location>
            <begin position="118"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="3">
        <location>
            <begin position="256"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="352" mass="38538" checksum="EDDC8F8C8AAB1DA0" modified="2018-01-31" version="1">MYSILEQKYQRLQKELMGGVIALGGIFCTGTLWYWLVEKWSLLDAAYMTVFTLATVGYGELYPLGKRGRMFTMCLILMGVMAIGFIVNRFTEALIQGYFQEGARIRQQRRLVDSLIGHYILCGFGRTGRQIALEFHAENIPFVVVDSAVHSVEEALTVGYTAVQGDATLDEILLSVGIDRAICIVAALPSDAENLYTILSAKTLNPKVRAIARATTEEAVKKLQRGGADAVVSPYITGGKRMAAAALRPQVMDFLDGVLTGTESSFYMEEFLVDPNSCVYVGQTLRDAHLRSQSGALVLAIRHPNGNLIVGPTGDTRIEGGDILICLGTAEQLRALNQILSPLSFRIPRPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F028</accession>
    <name>A0A2G4F028_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4346 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000064">
        <property type="protein sequence ID" value="PHX55124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55124">
        <property type="protein sequence ID" value="PHX55124"/>
        <property type="gene ID" value="CP500_012450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025595">
        <property type="entry name" value="DUF4346"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017260">
        <property type="entry name" value="UCP037673"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14251">
        <property type="entry name" value="DUF4346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037673">
        <property type="entry name" value="UCP037673"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4346" evidence="1">
        <location>
            <begin position="10"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14317" checksum="3D0C81ED40A72B3B" modified="2018-01-31" version="1">MSQTLDNLTAIDDKLSKRHIDLDPGGYFIIYLDRTTSLICAKHFTNIIDDRGLAIDPETGKPIPARGKVERTEATLFAARTAKELCVKILEETRPNPVTMLDHAAYLGREFVRAEIALLSDREYIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F073</accession>
    <name>A0A2G4F073_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rpsB</name>
        <name evidence="5" type="synonym">rps2</name>
        <name evidence="8" type="ORF">CP500_012385</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55174">
        <property type="protein sequence ID" value="PHX55174"/>
        <property type="gene ID" value="CP500_012385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="276" mass="31231" checksum="6588CB4A64B17DB2" modified="2018-01-31" version="1">MPVVSLAQMLESGVHFGHQTRRWNPKMAPYIFTERNGVHIIDLVQTAQLMEDAYEYMRVASEKGKKFLFVGTKRQAAGIVAQEAQRCGAYYVNQRWLGGMLTNWTTIKSRVERLKDLERREETGALDLLPKKEASVLRREMVKLQKYLGGIKSMRKIPDGVVLVDQRREYNAVLECQKLGIPIVSLLDTNCDPDLVDIAIPANDDAIRSIKLIVGKLADAIYEGRHGQLEGNDIDEDYDYEGAYEGAEYDVEIEELDDPNYVDPDDETDGDTEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0F1</accession>
    <name>A0A2G4F0F1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyridoxamine 5'-phosphate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_011920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55239">
        <property type="protein sequence ID" value="PHX55239"/>
        <property type="gene ID" value="CP500_011920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine-phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024624">
        <property type="entry name" value="Pyridox_Oxase_Alr4036_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024015">
        <property type="entry name" value="Pyridox_Oxase_FMN-dep_Alr4036"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PTHR10851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12766">
        <property type="entry name" value="Pyridox_oxase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04026">
        <property type="entry name" value="PPOX_FMN_cyano"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridox_oxase_2" evidence="5">
        <location>
            <begin position="4"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="193" mass="22083" checksum="95C23D514C0C7F39" modified="2018-01-31" version="1">MTLALWRSHLAGTLHRNRSLPVSRYLQLATVRTDGRPANRTVVFRGFLDDTNQLKFITDIRSQKVEEINVYPWGEICWYFPKTREQFRIAGQLVLVGAEHPDLALCSSRRRAWQEISEAARVQFAWPRPGANRAVSSAFEPVAPDAIEPLSNFCLLLLEPETVDLLELRGEPQNRLLYGRDGEGNWSVRELNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0I1</accession>
    <name>A0A2G4F0I1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA gyrase subunit B</fullName>
            <ecNumber evidence="12">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gyrB</name>
        <name evidence="16" type="ORF">CP500_011520</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="12"/>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55269">
        <property type="protein sequence ID" value="PHX55269"/>
        <property type="gene ID" value="CP500_011520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01898">
        <property type="entry name" value="GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011557">
        <property type="entry name" value="GyrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003586">
        <property type="entry name" value="Hint_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006142">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004042">
        <property type="entry name" value="Intein_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14528">
        <property type="entry name" value="LAGLIDADG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00379">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00305">
        <property type="entry name" value="HintC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="SSF55608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01445">
        <property type="entry name" value="intein_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50819">
        <property type="entry name" value="INTEIN_ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0651">Protein splicing</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="15">
        <location>
            <begin position="684"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="DOD-type homing endonuclease" evidence="14">
        <location>
            <begin position="811"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="domain" description="INTEIN_C_TER" evidence="13">
        <location>
            <begin position="1032"/>
            <end position="1056"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX55269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1197" mass="133750" checksum="0C6F1E9E191312DB" modified="2018-01-31" version="1">MTSSYSADQIQVLEGLEAVRKRPGMYIGTTGPRGLHHLVYEVVDNSIDEALAGHCTHIEVEINADGSVTVTDDGRGIPTGIVAKTGKSGVETVMTVLHAGGKFGGGGYKVSGGLHGVGISVVNALSEWVEVTVWRDQKVHLQRYERGNPVTELNAKPNKGDRTGTSVSFLPDTQIFSTGIEFDYTILAGRLRELGYLNAGVRITFSDHRLELLKSSEPRIETYCYEGGIKEYIAYMNREKQPLHEEVIYVQGERNNVHIEVALQWCVDAFSDNVLGFANNIRTIDGGTHLEGLKAVLTRTMNSIARKRNKIKENEPNLAGENVREGLTAVISVKVPDPEFEGQTKTKLGNTEVRGIVDSLVGEVLTEYLEFRPQVADAILEKAIQAFKAAEAARRARDLVRRKSVLESSPLPGKLADCSSRDPALSEIYLVEGDSAGGSAKQGRDRQYQAILPLRGKILNIEKTDDAKIYKNNEIQSLITALGLGIKGEEFDPAQLRYHHIVIMSVAGDEPTLVMDDTGRTEFVTIGGFIDDCVEGRRAADRYQVMSFDQTTHATRFRPLKAVIRHGHEEGMYKLTTRYNRSIKVTSSHSVFVFENNEVILKKGNEVKPGDLLVASRRLPRPAASPTQIDLLETFYSAELTKSLYLKGEDVRKVASQRVLAKVSVPDQWSEPRVQIDAEAWQKLIAQREAIGITQKQVAASVGVKQPVTVSQWERGISRPILSHFLTYLEAIGNSDNVVYEMLPSKIDDRLAQDDTSKNARWREVSCYKPLDDFTASEIAQLGEDVQIVPQAHSDKAFARYLPISRELIWFLGWYVAEGTLSQHQVSLNLGKKDQRFIPEMIAAIESVFNETPRQYNDPDSDGIKLYFNSVAAARLIQAWGLGKQAHLKQLPDIVFSLTEELQMAFLEGYFLGDGTTGGSHLSLITNSPKLKDGLLYLLGQLGMIASPTRHEPSTAVDAEIQTRHPYYSIAICSKNQLELCRQIWHRHANADLIEAHLARPSRKSSDYVPISDDLMGLKVISAEEIELVGDYVYDFSVEDDENFVCGTGGLCAHNTDADVDGAHIRTLLLTFFYRYQRALVEQGYIYIACPPLYKVERGRNHYYCYSDREMNNLIRNEFPANANYTIQRFKGLGEMMPTQLWDTTMNPETRTLKRVEIDDAAEADRIFTILMGDRVAPRREFIETYGPKLNMLDLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0K6</accession>
    <name>A0A2G4F0K6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Photosystem I assembly protein Ycf3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ycf3</name>
        <name evidence="7" type="ORF">CP500_011630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Seems to be required for the assembly of the photosystem I complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cellular thylakoid membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Ycf3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55290">
        <property type="protein sequence ID" value="PHX55290"/>
        <property type="gene ID" value="CP500_011630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00439">
        <property type="entry name" value="Ycf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022818">
        <property type="entry name" value="PSI_Ycf3_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 5 6" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR 1" evidence="5">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR 2" evidence="5">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="120"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR 3" evidence="5">
        <location>
            <begin position="120"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="20059" checksum="55B518EDCD9BC1CC" modified="2018-01-31" version="1">MPRTQRNDNFIDKSFTVMADIILKIMPAKKQAKEAFAYYRDGMSAQSDGEYAEAMDNYEEALKLEEDPYDRSYVLYNMALIHTSNGEHDKALEYYSQSLELNPRMPQALNNIAVIYHYQGEKEKESGNVEAAEGLFNKAADYWKEAIRLAPNNYIEVQNWLKITGRSQIDVYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0T6</accession>
    <name>A0A2G4F0T6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I-D CRISPR-associated protein Cas7/Csc2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cas7d</name>
        <name evidence="1" type="ORF">CP500_011240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55365">
        <property type="protein sequence ID" value="PHX55365"/>
        <property type="gene ID" value="CP500_011240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017574">
        <property type="entry name" value="CRISPR-assoc_prot_Csc2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18320">
        <property type="entry name" value="Csc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03157">
        <property type="entry name" value="cas_Csc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="337" mass="37387" checksum="0AEB49A488E73AF1" modified="2018-01-31" version="1">MSIAKLQPFLAPNYENFPKGRTIGIVVLRTTQSETIFRTEGTGEPMCSEYVQAGIEDTESIPRLVMTKRKQVAPERRKGREFLRSHNLLHTAPKTDAICALNTNAPCEMCVDCFLYGFAAGGEGAQKSRVWTEDAFSVLHSTELIADRTINAIFETGTMRDEKGNASTALNTSEYIKPGVHFLDIVTLKDVTADELRYTLGNILLTTRYGAVSSRIGRMENQILGVFGGIAELPSSLELVQGIYDKLKAKNTALEHPLKTAFLVDATQEIIGNWTNKRGISMQLSPAERDALIADVDRHWSLPEQETFLKRLDESYAPWRKVKSEGGGKKGKGKKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0U6</accession>
    <name>A0A2G4F0U6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55381">
        <property type="protein sequence ID" value="PHX55381"/>
        <property type="gene ID" value="CP500_010930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020346">
        <property type="entry name" value="Uncharacterised_15.3kDa"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17265">
        <property type="entry name" value="DUF5331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="449" mass="47964" checksum="FCDF4E70B3A5BBA8" modified="2018-01-31" version="1">MAFFDSFSVALKQKWLDYYQANRAWLLLHMTADNTVATPDGGKRPVSYLILGIAAALEPELQQLMLPFSRLKADADSLIEVLGLNFDPDIALGMPSDTIQPAASQSLTVAAPSAVATAALETLTAAPAATPEPATPEPATPEPTAPAATPEPTAPAATQSNQLGGAVLGAAGLVAGVVGATAIASALSSSDEESLEGFEEEEEAISDLDVDEEEEEAISDLDMEEEEAISDFDVDEEEAISDFDVEEEEEEAISDLDVEEDEEEAISDFDMEEDEEEAISDFDMDEDEEEAISDFDMDEDEEEEASALGELVVDEEEEEEALALGELDLGDDEEEEASEFGTLTSGDLEIEISDPFGEEDDDFVAEVIPDPFGAPISDDLDLDLGDLDEDGIDDFSVSDDDDFDGLGLDDLGDATIGDPDEDDLDALDLGDLDSDDEDEEISGFLSDFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0V7</accession>
    <name>A0A2G4F0V7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Photosystem I reaction center subunit PsaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Photosystem I subunit X</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">psaK</name>
        <name evidence="10" type="ORF">CP500_010985</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the PsaG/PsaK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55391">
        <property type="protein sequence ID" value="PHX55391"/>
        <property type="gene ID" value="CP500_010985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.860.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00474">
        <property type="entry name" value="PSI_PsaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035982">
        <property type="entry name" value="PSI_centre_PsaK_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000549">
        <property type="entry name" value="PSI_PsaG/PsaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017492">
        <property type="entry name" value="PSI_PsaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037101">
        <property type="entry name" value="PSI_PsaK_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01241">
        <property type="entry name" value="PSI_PSAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81563">
        <property type="entry name" value="SSF81563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03049">
        <property type="entry name" value="PS_I_psaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01026">
        <property type="entry name" value="PHOTOSYSTEM_I_PSAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="8712" checksum="1838FEACAD63271D" modified="2018-01-31" version="1">MFTPILLAVAPRTVEWSPTIAVIMIVCNILAIAIGKLTIQHPSTGTAMPSSNMFGGFGLGAVLGTTSFGHILGAGAILGLSYIGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Z9</accession>
    <name>A0A2G4F0Z9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="9">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gltX</name>
        <name evidence="13" type="ORF">CP500_010820</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55426">
        <property type="protein sequence ID" value="PHX55426"/>
        <property type="gene ID" value="CP500_010820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020752">
        <property type="entry name" value="Glu-tRNA-synth_I_codon-bd_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="11">
        <location>
            <begin position="2"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_2" evidence="12">
        <location>
            <begin position="332"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="248"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="515" mass="57647" checksum="CD757E6D6EF27783" modified="2018-01-31" version="1">MNVRVRLAPSPTGNLHIGTARTAVFNWLFARNQGGQFILRVEDTDLERSKSEYTDNILEGLTWLGMKWDEGPIFQSQRLEAYRQTVQILLDKGLAYRCYTTSAELDEMREAQKANKQAPRYDNRHRNLTPEQREAFEAEGRQAVIRFIIEDDRTISWNDMVRDTVTWKGSDLGGDMVIARASIGGDIGQPLYNLAVVVDDIDMAITHVIRGEDHIGNTPKQILLYEALGATIPEFAHTPLILNTQGQKLSKRDGVTSISDFKDMGYVPEALVNYMTLLGWTAPDSTQEIFTLSEAAAVFSCDRVNKAGAKFDWDKLNWLNSQYLHKMPVPQLTDLLIPYWQKAGYEFDIEADRPWLEQITTLISQSLVRLTDAVDMCKVFFSTTVEYEEEAIAQLQQPKVAEALQAVLEALESHSTLISAEAQKITKKLSKEKNLNKGLIMRSLRAALTGAMHGPDLIESWVILHQRGTAQTRLQEAINNLNLPVVKTVESSVAAVEISAVATVVAAVEIPAANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F186</accession>
    <name>A0A2G4F186_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Peptidase C39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_010455</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55519">
        <property type="protein sequence ID" value="PHX55519"/>
        <property type="gene ID" value="CP500_010455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="488"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="521"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="598"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="629"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="713"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="741"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="59"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="12">
        <location>
            <begin position="337"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="491"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="804"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="271"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="839"/>
            <end position="846"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX55519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1049" mass="117609" checksum="F0A58A041118AABD" modified="2018-01-31" version="1">MNKSLGVKNYFSRSPESVQNVPAIQQLLEEIGAKPTVVAKINAACEIYDFQLGDEITKYQNLDSDSHSLDKEQIDRNCYLVSQGRVRLLTVTGTKQEENSAVVLEVGEIFGTDNLFVESGVAYRAIAVGTCQMARIDVSKLQLILEECPELQQHLQAQFQQRQRLIFFKTQTELRSLDPQQQQTLWPQLLPYIEETRIPAGVSLAQQYQKSPSHFWLRSGQIQGEKPPIIGSDWGHPDSGSEDWQAKTDLLVYQLNSTQWEIATAAISDNSNSPPKIIRKPHNSTLIQPPKNSNHTSQTKSPKLTVVGNSQSQAVSITFPKPKRRKWLGSGHPFIQQQSSADCGATCLAMISEYWGKKFSLNYLRELAEIGRSGASLKSLAKAAEKMGFQARPVRASLTPLRNQNPWIAHWQGNHYVAVYRFKNQQVLVADPAMGKRWMSVKNFAENWTGYALILDPTPQLYRNDITEQKGIKTQNFLGIVWPYRSTIAQILVISLFIQIFGIVTPLFTQVILDQVVVSKSIATLHVFAIGLLLFGIWRSLLGASRQYLLDYLSNRIDLTLISGFISHTLSLPIKFFESRQVGDILTRVQENQKIQAFLTRQAITAWLDALTAVVYIALMVYYNWRLALLVLALIPPIVILTLVATPFLRKISREIFNASAKQNSSLVEMITGVATIKATASEREMRWRWEDQLTVMINTQFRGQKLGNSLQIIGGAINTLGGTALLWYGAMLVIQDELTIGQFVAFNMMIGSVISPVLSIVGLWDQFQEVLVSIERLDDVFSAEPEESPSKPMLVLPRIQGNVKLENVSFRYSQDDERNTLQNLSFEVQAGETVAIVGRSGSGKSTLVKLLQGFYYPEKGRLTIDGHDIRHISLQSLRVQLGVVPQDCFLFSGTILENITLYKNGLGADSRSLEEAIEVAKLAEAHAFIQDMPLGYQTPVGERGTSLSGGQRQRIAIARALLGDPRILILDEATSSLDTESERRFQQNLARISRDRTSFIIAHRLSTVRNADRILVLDKGILAEQGNHEQLMAERGLYYHLAQQQLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1B0</accession>
    <name>A0A2G4F1B0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55564">
        <property type="protein sequence ID" value="PHX55564"/>
        <property type="gene ID" value="CP500_010050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="779" mass="81591" checksum="83E78FBE3AD21CCB" modified="2018-01-31" version="1">MPDNLALLDKNDILNGSSAQDQADCGCPFKKAPTVETVSNAQNIQNILGLGSNDTLESSIAPDFLNGNTGNDLISVSADGDIGRSTSQVRIGSLSRDGSAYILTEGSDTFTIPLGLLDTLIGGLRGLGGADSITGSESGDIVYGDEGNDRIEGRGGADLLYGGLGNDFLSGGAGQNGLLGGAGADTLQGGESADGVNGNAGKDVIFGGGGDDFLRGGRGNDIINGQDGNDFLIGDFGNDTLTGGAGQDVFVLRSEATLGSPTFDLITDFQRTIDFIGLSTNLKESDVILESKVQPAGGSAVDIKVAATGALLGTVLGVKPDDLKGRFRPYDVEPDRPEDKVTIDLPEVKKLSDNKFQMEFPASDGSKYTVVFQDDADGRFVESVIFVPNPTTGVRGSTTRMSRDGTRADVTLEGSNETVRVENQPSKEPGKPDQGVISRRLKDGQIIDTVTFPLPMEPPPVSTPKPPVTPPPVTPPTVGQPDFAKACQSFQEFCNKVEKLSKVIDTVALGLATGGLVFPPLELAAGAAEAVAISLKVVKYTCIVLTGSDIDLGLSAISDLFGQVVKRSGDLKKAVQPDYKRINEVTYSAAGLINSFRKKEPTASKEDLLPQFRKFLAEKYNFPFDACDKPATTPAPAPTCLPGGGSIFKAEVIPSVLNYGQAAEVKITYCDSQNKLNNILVELSTRSGKQTKNIPISSPSGTVSFEIRNKPNAFGDCDDLGFAATGRPGISGSLVITGIRDNANGFASFGALPDFFLTGGLTQIPTQFDSRKVCDAELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1B7</accession>
    <name>A0A2G4F1B7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55257">
        <property type="protein sequence ID" value="PHX55257"/>
        <property type="gene ID" value="CP500_011795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="11775" checksum="336D04E667170FCB" modified="2018-01-31" version="1">MVSGLFSCPHCHSHLVISWSGHFVRDPFSLKQLTVGKMLRRESRPLARIQRDLGIGKHFPLLALLGSAVFLGFAIVTTEQSLPRSQPFQGFLEWVSGSGNSQNISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1K0</accession>
    <name>A0A2G4F1K0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid oxidation protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55640">
        <property type="protein sequence ID" value="PHX55640"/>
        <property type="gene ID" value="CP500_009515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="15932" checksum="7CB294FD6F1CF8A8" modified="2018-01-31" version="1">MPAKDVFHKAVRKALETENWIITDDPLKLDVGGVEMYVDLGAEKLIAAEKNGTKIAVEVKSFIGTSNIYEFHTAMGQFINYRVALEEKYPGRELYLAVPDGTYQTFFNLQLIQKIIQRFEVKLIIYDATNEVIVQWKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1K5</accession>
    <name>A0A2G4F1K5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55636">
        <property type="protein sequence ID" value="PHX55636"/>
        <property type="gene ID" value="CP500_009820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="197" mass="20308" checksum="A17B3D57F74C2CD5" modified="2018-01-31" version="1">MLVGSVLSLGSLVAWKMYQERVNLQIKLPSDVPLPESPSPTPAAPANRLPTIPPAPATAQSPASLPSPNPTQIPSLSGVPQLASPSPSPSPSASPAAETAVTERVSFEPGAIGVTLTNSLPDNKSKRYLLECNSGQSMTLNVQEGTVSAAIIAPNGEKVGTANSTTPWQGQLPSSGDYTIEISGDNKANYGVKIEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1M5</accession>
    <name>A0A2G4F1M5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_009540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55645">
        <property type="protein sequence ID" value="PHX55645"/>
        <property type="gene ID" value="CP500_009540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="36"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="592" mass="66579" checksum="8D2E95C849D27CAD" modified="2018-01-31" version="1">MICCINPNCEKPENPDGQTYCITCGVKLVPILRSRFRMIGFLGKGGFGRTYLAEDIDKLNQRCVVKQLAPNVQGTWAINKAVELFQQEARQLQQLGQHPQIPSLDAYFEENNYLYLVQQFVDGDNLLKLLQKRGIWQESQIKQLLLELLPVLKFIHEQKIIHRDIKPENIMRRRSDGLLVLIDFGVSKQLSGTVMSKPGTRIGSHGYTPLEQLQEGEAYPASDLFSLGATAFHLLTGVYPLGLWVEHGYSWIANWQQHLKKPIDNKLELILSKLLAKDIVQRYQSAEEVLTDFQRQSTPTPTPTPTPAPISTPTLTLQRFDFEVATVNARGNITNRQRHQAQFFRENLGGSATLDMVAIPGGSFVMGSPSTEAERSSDEGPQRTVTVAPFFMGKYPVTQAQYQALMGNNPSHFKGFFKSKQLPVEQVSWDEAVEFCRKLTQKTGKTYRLPSEAEWEYACRAGTTTLFYFGDTITPDLVNYQGNNPYGAAPKGLYRQQTTDVGSFPPNPFGLYDMHGNVCEWCSDKWHDNYNGAPTDGSSWETGTDNNRVQRGGSWDLNAVNCRSAFRVYDSAGSRWRCRGFRVAVASVSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Q1</accession>
    <name>A0A2G4F1Q1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55690">
        <property type="protein sequence ID" value="PHX55690"/>
        <property type="gene ID" value="CP500_009330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007053">
        <property type="entry name" value="LRAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04970">
        <property type="entry name" value="LRAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51934">
        <property type="entry name" value="LRAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="LRAT" evidence="2">
        <location>
            <begin position="6"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="253" mass="26051" checksum="B6652579F66C89F9" modified="2018-01-31" version="1">MAKGDHIYTQHLPHTHHGIDCGDDSVIHYGKRQGEKICRISKNDFASGNKIHVKEYGKCYSDDEVVRRAESRLDEKGYDLFSNNCEHFAYWCKTGKDKSEQVAQAQGGVAGLVGGVAIGTGTKVATKIATEAAIQSANPISKFLINVGLKQAPAVAGTAAAGIVNVGGIASGLVADFIVGKILEDDEALTESEREARKNGRIAGQVASTIGGVGGGIAAVTVGGSAAVAAAVAAPAVLGIAIGLGAYHLLKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1S2</accession>
    <name>A0A2G4F1S2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CAAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_010825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55427">
        <property type="protein sequence ID" value="PHX55427"/>
        <property type="gene ID" value="CP500_010825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009579">
        <property type="term" value="C:thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025564">
        <property type="entry name" value="CAAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033344">
        <property type="entry name" value="CURT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33222">
        <property type="entry name" value="PTHR33222"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14159">
        <property type="entry name" value="CAAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="CAAD" evidence="3">
        <location>
            <begin position="58"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="16039" checksum="BAA7584D6E57A3D5" modified="2018-01-31" version="1">MTSSNEPETTAIVTEIPTGDDTESAIDTTKVTVTQEDPNQAQQIKEQLISILSEFPAYIGAFYEQYKSPLTVVGLILVSIISLKVLLGIVNELNDIPLLAPTFEIIGIGYTVWFVYRYLLRSSNRQQLGQEIQAIKEQIFGKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1V3</accession>
    <name>A0A2G4F1V3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA recombination-mediator protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55744">
        <property type="protein sequence ID" value="PHX55744"/>
        <property type="gene ID" value="CP500_009195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044995">
        <property type="entry name" value="TMT/HOL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183">
        <property type="entry name" value="PTHR32183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="167" mass="18672" checksum="3ACE155EF3E9D309" modified="2018-01-31" version="1">MSQSIELPRVDDFLQELAAIQQTSSKRLALLGSRHVPITHQQLIEMLSYALVLSGNQLITSGATGTNSAAIRGAMRADPNLLTVILPQSLSRQPRESREQLEQVIHLVENPKNDSLSLPEASALCNQEIISRCQQMLCFAFHESHTLLKTCQDAEEQRKVVTLFYFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1X3</accession>
    <name>A0A2G4F1X3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="7">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aspS</name>
        <name evidence="9" type="ORF">CP500_009135</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55764">
        <property type="protein sequence ID" value="PHX55764"/>
        <property type="gene ID" value="CP500_009135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="144"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="7">
        <location>
            <begin position="202"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="224"/>
            <end position="226"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="540"/>
            <end position="543"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="595" mass="66957" checksum="CC865D5F0D38FE27" modified="2018-01-31" version="1">MRTYYCGELRSEHIGQTVTLYGWVDRRRDHGGVIFLDLRDRSGIVQIVSDPQRTPDSYHGAEALRNEYVVKITGRVTNRPADSLNPKLPTGEVEIYADEIELLNGVRKQLPFQVSTADNESVREDLRLKYRYLDLRRDRMSRNLQLRHQVVKAMRRHLEDVGGFIEVETPILTRSTPEGARDYLVPSRVNLGEWYALPQSPQLFKQLLMVSGLDRYYQIARCFRDEDLRADRQPEFTQLDMEMSFMSLEEILELNEGLVCNIFQSVKGVELPHPFPRLTYAEAMDRYGSDKPDTRFGLELVDVSDLMKDSGFKVFSGAVAAGGIVKVLPIPGGNDAISNVRIKPGGDLFKEASEAGAKGLAYIRVRDNGEIDTIGAIKDNLTEAQKQELLDRTGAQPGHLLLFAAADVTTVNKTLDRLRLFVGSELGLIDKDKMNLLWVTDFPMFEWNADEKRLEALHHPFTAPHPDDIDDLKTARAQAYDLVLNGTEVGGGSLRIYQRDVQERVFEAIGLSTEEAYNKFGFLLDAFEYGTPPHGGIAYGVDRLVMLLAGEESIRDVIAFPKTQQAGCLLTNAPSGVDEKQLKELQVRSTYVPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F227</accession>
    <name>A0A2G4F227_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55798">
        <property type="protein sequence ID" value="PHX55798"/>
        <property type="gene ID" value="CP500_008905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="240" mass="26840" checksum="519F3DEBBD666BC1" modified="2018-01-31" version="1">MTLKAVLFDFNGVIINDEPIHEQIVDQLMLDENLQLKRGEFREVCLGKNDRTCIAELLKRRGRFLTEAYLDRLLLRKSQAYHAKIDSLETLPIYPDLADFIAKIRAAGLKMAVVSGAMRSDVELVLNLAGLAQSFELIVAGDDTMTSNPAPDRYLLAVELMNRQYPGWNLQPGECLAVEDTFAGIEAAKKAGIQVLGVTHTYPFHMIQRQANWTVDYFADLELDRVAEICAIGPTEPTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2L0</accession>
    <name>A0A2G4F2L0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_007545</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245728">
        <property type="entry name" value="M.Tbo703ORF7545P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56001">
        <property type="protein sequence ID" value="PHX56001"/>
        <property type="gene ID" value="CP500_007545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="292" mass="32070" checksum="7867832DA63AD16C" modified="2018-01-31" version="1">MRVASFFSGIGGFDLGFEKAGMNVVFQCEIDKSCRQILKRHWPQVPIHEDIRTLTHSTIPAADLWCAGWPCQDLSNANTERKGLAGERSGLFYKFMELVAEIQPAWLVLENVPGLLSAEQGTALEVVIDTLEAHGYLGGWLSCNARHTGLPHDRDRVFFIASFRSKRACRIFTDSGELSGDSAARKSREKKTRSSVCESIIGDTPLVVQRRGGFGYTLAKSICPTLRAQTGGHQGGHSDRPILCGEKLDLDRMGKADGISSRMDGRRGRLLGNAVVPGIAEWIGRKILEIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2M6</accession>
    <name>A0A2G4F2M6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56024">
        <property type="protein sequence ID" value="PHX56024"/>
        <property type="gene ID" value="CP500_007680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009956">
        <property type="entry name" value="Post-segregation_anti-tox_CcdA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07362">
        <property type="entry name" value="CcdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8605" checksum="A088F8300EF8CB23" modified="2018-01-31" version="1">MNESSIPPHGSSEKVELSIHLDAELLDQIKHLTNDPSKVIETAIRQWLRGDRREDELALSLRRNPPVPPRGEWND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2N0</accession>
    <name>A0A2G4F2N0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Homoserine kinase</fullName>
            <shortName evidence="11">HK</shortName>
            <shortName evidence="11">HSK</shortName>
            <ecNumber evidence="4 11">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">thrB</name>
        <name evidence="15" type="ORF">CP500_007725</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="4 11"/>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56033">
        <property type="protein sequence ID" value="PHX56033"/>
        <property type="gene ID" value="CP500_007725"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="13">
        <location>
            <begin position="88"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="14">
        <location>
            <begin position="238"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX56033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="336" mass="35289" checksum="03195A5506C1D243" modified="2018-01-31" version="1">MSVISTITVTVPATTANLGPGFDCIGAALSLYNSFQFSRLEPSATEKLKITVTGQEAAKVKTDDSNLAYVAFVTLYDRLNQSPPPVAIHIDMRVPLARGLGSSATAIVGGLVGANELAGAPLSQVEVMQLAIELEGHPDNVVPALLGGCRLAASNTPPQPPLSKGGLREESPLTPPLSKGGQGGVPWQICDIPWHPDIVPVVAIPDFELSTAEARRVLPADYSRADAIFNAAHLGLLVRALETGDRDWLRCALQDKIHQPYRQSLIRGYEAVQQAALNAGACGMVISGAGPTLLALTDVTNADAVVREMGAAWMEFGVKADVRAISLDTQGAQVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2N8</accession>
    <name>A0A2G4F2N8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-directed DNA polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56012">
        <property type="protein sequence ID" value="PHX56012"/>
        <property type="gene ID" value="CP500_007600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03487">
        <property type="entry name" value="RT_Bac_retron_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000123">
        <property type="entry name" value="Reverse_transcriptase_msDNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00866">
        <property type="entry name" value="RNADNAPOLMS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="2">
        <location>
            <begin position="163"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="465" mass="53758" checksum="F7AE3D57C192D1FE" modified="2018-01-31" version="1">MTDQPRTRQELYDRIRSTSKEEFILEEMIRFGFWPAQGEIPEDPADEIRRMGEIRRELDELRRENSLLHNEQALRKEMLKQRLIQSRQKQQETKERREKERQERAENWQQRKQQEICYLGDGVSAGLNNTNCNEERLQNYQLPLCNTAAEIAAAMEISVGQLRFLAFDRKTSHISHYIRFKIPKKTGGERLISAPMPRLKAAQHWILVNILEKLELHNCAHGFRSSHSIVTNAQPHVGSEVIINFDLKNFFPSISYKRVKGLFQSFGYSEAAATIFGLLCTEPEIEEVELDSKTYFVAVTERHLPQGSPASPAITNILCRRLDQRLDRMASELGFVYTRYADDLTFSASGDSLQNICNILRHTESIVAHEGFVINEEKTRILRKNRQQEVTGIVVNEHLSISKKVLKRFRATLFQIEKDGPDGKRWGNSEDVIASIQGFANFVAMVNPEKGAEFLEQVQRIKNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F304</accession>
    <name>A0A2G4F304_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56118">
        <property type="protein sequence ID" value="PHX56118"/>
        <property type="gene ID" value="CP500_007375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="8003" checksum="9CBE2734FD7B75ED" modified="2018-01-31" version="1">MGLVRIRVRELAAERGWTFKEVAERSGVVYSTITTYARRSEISMVDFTAIHKLARAFGVMIEDVVEIIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F354</accession>
    <name>A0A2G4F354_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Assimilatory sulfite reductase (ferredoxin)</fullName>
            <ecNumber evidence="5">1.8.7.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_008355</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3 H2O + hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] = 7 H(+) + 6 reduced [2Fe-2S]-[ferredoxin] + sulfite</text>
            <dbReference type="Rhea" id="RHEA:23132"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.8.7.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.7.1" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55897">
        <property type="protein sequence ID" value="PHX55897"/>
        <property type="gene ID" value="CP500_008355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050311">
        <property type="term" value="F:sulfite reductase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011787">
        <property type="entry name" value="SiR_ferredoxin-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="PTHR11493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02042">
        <property type="entry name" value="sir"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0883">Thioether bond</keyword>
    <feature type="domain" description="NIR_SIR_ferr" evidence="11">
        <location>
            <begin position="68"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="10">
        <location>
            <begin position="168"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="11">
        <location>
            <begin position="365"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="10">
        <location>
            <begin position="446"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX55897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="660" mass="74324" checksum="A122558D18541A40" modified="2018-01-31" version="1">MTTSATSAPAARKPSKSEGLKERSNYLREPVATELLQETTHFTEEGIQILKFHGSYQQDNRDNRVKGQEKDYQFMLRTRNPGGFVPPQLYLTLDKLSEEYGNHTLRVTTRQGFQLHGVLKKNLKAVFSSIIKNMGSTLGACGDLNRNVMAPPAPYKNRPEYEYALKYANNVADLLTPQTGGYYEIWLDGEKAISAEEDPAVKAARQSNGNGTTFDDKEEPIYGQHYMPRKFKCSVTVPGDNSVDLYSQDLSLVVFTNEAGELEGFNVFAGGGLGRTHNKEETFARVADEICYVAKDDVYDLVKAIVATQRDFGDRTDRRHARLKYLINDKGVKWFQEKVAEYFGKPLAAFKPLPEWKYIDFLGWHEQGDGKLFLGISVENGRVKDEGSFQLKTALREIVQKHNLPMLVTPHQNILIYDISPDIKQEIQSILARCGIQGETAIDPLVRYAMACPAMPTCGLAITESERVIPSILERIRVLLTKVGLENEHFVVRMTGCPNGCARPYMAELGFVGSFQESYQIWLGGSPAQTRLAKPIEEKLHVNDFEAFLEPIFVYFKQKRQLSESFGDFCDRVGLESIRQFVTNYQSADSMTTEINELEVTSSNDDGNETAAAGKVRRRISVRDEIYNELKEEAARQGKPITQLATEAISTYLNKIKEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3R2</accession>
    <name>A0A2G4F3R2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome biogenesis GTPase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56361">
        <property type="protein sequence ID" value="PHX56361"/>
        <property type="gene ID" value="CP500_005825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019991">
        <property type="entry name" value="GTP-bd_ribosome_bgen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016478">
        <property type="entry name" value="GTPase_MTG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006230">
        <property type="entry name" value="MG442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03596">
        <property type="entry name" value="GTPase_YlqF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="3">
        <location>
            <begin position="14"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="58"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006230-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="33272" checksum="2EF954252A957749" modified="2018-01-31" version="1">MKIHWYPGHIAKAERALKEQLKRVDVVLEVRDARIPLATHHPQMQTWVGSKARILVINRMDMISPRLRQEWEAWFEARGEAVYFTNAGHGQGIDALADAVQNAGVQLNQRRFDRGMLPRPVRAVVIGFPNVGKSALINRLLGRKVVDSARRAGVTRSLRWIRISDEIELLDTPGVIPTRINNQDNALKLAICEDIGEAAYDNQVVAAAMVDLLLGLEATDDTLISVSGFKSRYKLDALSTNGENYLHEIAKDRHQGDVERMARQMLNDFRTGVLGQLPLELPPFLSDESPNSSKTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3U9</accession>
    <name>A0A2G4F3U9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA small subunit methyltransferase G</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">16S rRNA 7-methylguanosine methyltransferase</fullName>
            <shortName evidence="2">16S rRNA m7G methyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsmG</name>
        <name evidence="3" type="ORF">CP500_006850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the N7 position of a guanine in 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56157">
        <property type="protein sequence ID" value="PHX56157"/>
        <property type="gene ID" value="CP500_006850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="PTHR31760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003078">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00138">
        <property type="entry name" value="rsmG_gidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="120"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="27522" checksum="05909CD62F88EE89" modified="2018-01-31" version="1">MNQMTMPVLPEMNELWQESLNWVPNESQQQQFQRLYELIVEGNRHLNLTRITEPIEFWEKHLWDSLRGIARLLPANGNSGEIRDFTGQPMLKAMDIGTGGGFPGLPVAIALPNLSVTLLDSTRKKIDFLETVLPSLTIQNAGTLLGRSDEIWRQPHHKAAYDIALLRAVGAASLCAKYALPFLKNGGLAVLYRGNWTAEEEADLQSAIGHLGGTIESVEAFTTPVSQGARHCVYLRKVVQQLERPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Z0</accession>
    <name>A0A2G4F3Z0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56480">
        <property type="protein sequence ID" value="PHX56480"/>
        <property type="gene ID" value="CP500_005160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="20"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="171"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="315" mass="34000" checksum="3FE153AE331FA4A9" modified="2018-01-31" version="1">MTFKLELPEQKLSGLETKLAIATALAASVFLALTPVLIRISESFLSPNATIFNRFWIATVILGLWNGLFLQNRQTNPPVKDSSNTKRLFVPLLVLVIAFVSTQLLWAWSLAQTTVANSEILHCLSPGFTTLAGWLLFAQRFGGRFLIGMVVATGGTIAIGVSDMSHSSSLFGDGLALLSAVFWAAYIMSMEKLRNYLSPTIIVMWASGSCTLLCLPVMLIAGDEVLPYSAGAWLTLIVLALNTVVCHSLVAYAIKWLSSGLMSTILLLSPVLTAVVAWALFSETLSPLNLLGFAVIMVGVYLAISDEGELKIPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F403</accession>
    <name>A0A2G4F403_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M23 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56465">
        <property type="protein sequence ID" value="PHX56465"/>
        <property type="gene ID" value="CP500_005390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="277"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="473" mass="50058" checksum="25BFF13F942DBC8E" modified="2018-01-31" version="1">MAREPRYQEPAYEAEYAQPPAAPATPNYYLPEPALIPLPEATAQEPEPPFEAPVNPANAYNDRPNYNSYEPPTIVEFAERSRGSEQSGADAPSANYEPATADAGPTNNSNPNPIARDSYVAAPPSENVPRNVADNVPRSVANKGGDNVTSTLGQALQKIDSQLWGASTRQAKYVDGLVDSANSGESTEAGYYANAASSGYSGRAPSPGSSIGLGPIEVGPISVSSGSNTGFAYYNLTPRPAGKFGNGNTSLLFPLSIAAAITSPFGWRTHPVTGNGRFHTGTDLGADLGTPVLAAYAGQVAIADWLGGYGLTVVLNHQKNSQETLYGHLSELFVKPGEFVKQGDTIGRVGSTGMSTGPHLHFEIRQMTAQGWVAIDPGSQLEFALARMIGTLEIAKLPPKMPEILAAKDLKGFKDLENNLPQLPPLPVGMDIEVHNIQPPFPELLKADVAASQLKESPVSSPKTQKTQKQASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4F0</accession>
    <name>A0A2G4F4F0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Type II toxin-antitoxin system HicA family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_004325</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HicA mRNA interferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56642">
        <property type="protein sequence ID" value="PHX56642"/>
        <property type="gene ID" value="CP500_004325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038570">
        <property type="entry name" value="HicA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10492" checksum="CB39EE55A4278D0B" modified="2018-01-31" version="1">MNSMSGKELAKLLERNDWILLRVQGSHHIYGKAGSSIRISVPIHGNKSLKVGLLRHLLKQAGLSGNTHQNTNTVEESNSENNEANESDSIDEEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4J4</accession>
    <name>A0A2G4F4J4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AbrB family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56631">
        <property type="protein sequence ID" value="PHX56631"/>
        <property type="gene ID" value="CP500_004265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027360">
        <property type="entry name" value="AbrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42182">
        <property type="entry name" value="PTHR42182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14250">
        <property type="entry name" value="AbrB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="79"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="14378" checksum="B0671906DA705FBA" modified="2018-01-31" version="1">MVKKKSIEPLEGEGLIKKVKDLENLTKEEKARACGYYTVTKNGVERVNMMKFLNALIDAEGIQLDGKQNGNGRGGRSASYRISVQSNGNLLIGAAYTKQMELQPGDEFEISLGRKHIHLRQIDQEEEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4J7</accession>
    <name>A0A2G4F4J7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56676">
        <property type="protein sequence ID" value="PHX56676"/>
        <property type="gene ID" value="CP500_004060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37953">
        <property type="entry name" value="PTHR37953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="168" mass="18161" checksum="FD61DB5FBED7F872" modified="2018-01-31" version="1">MPNALLPIGLIIFLLGCSPTLPVASNSDPGIFVSQSPTPTSSGQVLPVSARAQIADRPIELEVAKTPEQQAMGLMYRTSLPDNRGMLFEFKPARWVNFWMKNCQISLDMIFLRDGVVTAIQAGAPPCTADPCPTYGPDTIVDQVIELRSGRAAELGVKVGDRIAIDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4K3</accession>
    <name>A0A2G4F4K3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1688 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56641">
        <property type="protein sequence ID" value="PHX56641"/>
        <property type="gene ID" value="CP500_004320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012469">
        <property type="entry name" value="DUF1688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687">
        <property type="entry name" value="PTHR31687"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07958">
        <property type="entry name" value="DUF1688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="415" mass="46184" checksum="8D70C801126E07CB" modified="2018-01-31" version="1">MNQPSIELETVEYLRSPVAIRQKCDRLFNLAYENKLRYFRIDLTQLDKAANYVIDTTRENYPDFNIPFHSRWRHFEVGNQPRLAELDVALAQFTLLEKAQIKFDLAIISVLLDAGAGADWQYWEPETGQIYRRSEGLAIASFRMFCQGIFSSNPDFPWQADSLGLSQLTLEKLALGFQVSPENPLVGLVGRLELLQGLGNAICQHPLLFGCENPRPGNLAKYLLDTHSSGLKTIKAATVLSAVLTGFGEIWPGRYAIGGVNLGDVWRHPALQGEDLDAELVPFHKLSQWLTYSLLEPLQELGLEVVELDELTGLAEYRNGGFCLDIGLLQAKDLVVFEKSYLPGSEVIVEWRSLTVNILDKIATAMREKLDLSATDLPLVKILQGGTWAAGRKIAGELRAGGVPPIQIKSDGTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4L2</accession>
    <name>A0A2G4F4L2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56723">
        <property type="protein sequence ID" value="PHX56723"/>
        <property type="gene ID" value="CP500_003680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="11256" checksum="E9B99D595E86443C" modified="2018-01-31" version="1">MLKNGQDARSTRKFTLCGTGILPVAFQNGQDARSTRKFTLCGTGILPVAFQNGQDARSTRKFTLCGTGILPVAFQNGQDARSTRKFTLCGTGILPVAERGAISQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4N5</accession>
    <name>A0A2G4F4N5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfatase-modifying factor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56753">
        <property type="protein sequence ID" value="PHX56753"/>
        <property type="gene ID" value="CP500_003845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="425"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="692" mass="77049" checksum="69D3152420BB68A2" modified="2018-01-31" version="1">MAKVGLLIGVSEYQPGLNPLPAAVKDIEALQRVLQDPEMGGFDEVKTLANPEPHAMQLAIETLFDSRAKDDLILLFFSGHGIKDDAGRLYFASRSTRKNPKGNLIKSTAISASFVHEIMNNSRAKRQAIILDCCFSGAFDPGLQAKDDGSVDLRTQLGAEGRVVLTSSSSTEYSFEQQGSDLSIYTRYLVEGIETGAGDTNSDGLVSILELHEYAVSKVQEELPAMTPKIIVLKDKGFEIVLAKARVADPKLKYRKAASRYANVGTIRPAGRAILNTLRQQLGLTADETAEIEAEVLRPYQERLANLQKYRETLIAEAEHEYPLSEFAREELNTLQQMLLLRDGDVLPIQQEIEALFTQQAEAKRQAQEQAKTSQVSSPQNNVGTKLQRFEFDVITVDKTGKENSRTKKSAEVFAEDLGNGVLLEMVQIPQGSFLMGSPKNELERRDNEGPQHQVTVPAFLMGKYAVTQAQWKTVANLPQLERKLRPDPSSFKGANRPVEFVSWYHAVEFCARLSQHTGKPYRLPSEAEWEYACRAGTTTPFHFGETITTDLANYRGTDNEEYKWSGSYGAGPKGIDREETTPVGSFRVANAFGLYDMHGNVWEWCADPWHSGYQGAPTDGTVWDEICNDNRYQNNIHLLINTKEDKRTQVLRGGSWRADPGDCRAAIRNNVQPRIAANVFGFRVVCVAAWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4R9</accession>
    <name>A0A2G4F4R9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_003690</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56725">
        <property type="protein sequence ID" value="PHX56725"/>
        <property type="gene ID" value="CP500_003690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="258"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="319"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="105"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="150"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="535" mass="59882" checksum="66DE8B1A6C977E69" modified="2018-01-31" version="1">MKLQSFRFRITLFSAVLASIALMGFSIVSWWLIYDAKVKRLDAEIKNQLIQSTRPQSTQWETYTDSLPSVLGMNGATTVALLVNDRDGNLLYRSRQWQDGLDANSLWRSLPQPPPDPDRIPFELEPPPPPHPPYPLSPIAPLDPPHPDRPNSFSPRERRPPRDRHPQPDRPNSFSPRERRPPRDRPDFPQVFQAKLATRRSRKAVWRVGAIHSPQTQVAIAVNLQAIDLEMASIGNIFLISIPVVLVLVAGGAWVISRSILYPIGRLTTAIRNVTVQGLDHRVPIGSTDIEFLELIFVFNQMLERLERSFQQASRFSGDAAHELKTPLAILQGQLERALHQSEPGSEIQQTVSNLLDEVRRLTEITRKLLLLSLADAGRMSLNWVEVNMSALLAEIAEDMELLAPDLEVQMAISPNLFIKGDRDLLVQVLQNLVGNAIKYNLPQGWLKLQAKCQGKRVIVKIVNSSQDISLSEGDRIFDRFHRGDSTQTQKIEGSGLGLSLAREIARAHGGDIKLDAAILGQTGFILSLPVGDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4W1</accession>
    <name>A0A2G4F4W1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56790">
        <property type="protein sequence ID" value="PHX56790"/>
        <property type="gene ID" value="CP500_003410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="548" mass="61951" checksum="E5F7FF32B59130F3" modified="2018-01-31" version="1">MAALNRSTLRRLQKLPQIPSVWEGDRRPLSNADSHMIVEDDDILEDGGECILWVDGSEGVVRAMDMVGPDAGPEAIVRALLRAMEHPQSPSPAVRPQKIVVKNREIQFYLRGVLQDLGIAIDHVPELPLIDEIFRGMEEVAVNRPPELPPQYADVLMEKAAQIWHDSPWQTLREHQIISIEINQWDVASLYVSVLGQGRMDYGILLYRSLESLKRFRERVVNDDSFEDLEQAFLGQDCLFLTFESVAEIDEDDEEEIDLADLDPSEIEPNFGNLHPLEGLRSILYEEEALTMLVALEALHRFFRSSRRKLTAETFPTLSSRYRIPIPQPDGEAQQISVKVSTMPDVSDELLKMLEDDDDDDDDDDEFEMPLLRDDLVPPNSFLSLGVIPWTTVDFLRGNAQFYQGAEGDISPNGDGLPVVMIQTSNPKAKTMIQDLQEAGGVKAICFNPGEDPFQEEQYDLGILQAKNGDLYLFGEFNEDDPVHQEARKKWERRCQSTKGWCGLVIAKGLMGASRGQPQFKDMIALFEVRWVSAKELGIGPLQLMPMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F540</accession>
    <name>A0A2G4F540_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56849">
        <property type="protein sequence ID" value="PHX56849"/>
        <property type="gene ID" value="CP500_003205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="284"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="547" mass="61587" checksum="3532F7CFD0B39E0A" modified="2018-01-31" version="1">MTADSIQIKVGDAVNCDRNNPFEALIKRLDLMIRAHYSLLYIVGAEEEPVEAVIAQVALFVTPARRVLFWDIVRGWEDNGSGKGSVMAALDRIGKTAVEEYTIFVLRDLHPVLKYPYTEKNAPVVRELRNLTRELKRSKKTIILTSHALELPEELQEEVTVIDFPLPNVQEIEHLISHVVTKPEQLQVTSLAREQLVKACQGLSRAKIGRVLAKALAAKEQINESDIDGILEEKQQAIRQTGILEFFTSQESLNSVGGLENLKLWIKMRKDAFTDEARRYGLPNPKGVLLVGVQGTGKSLSAKIIASEWRLPLLRLDTGRLFGGIVGESESRVKQMIELAEAIAPCVLWIDRIDHLFGNMMTGGDADSGTSCRVFGSLITWMQEKASQVFIVATANNVRILPVQLLRKGRFDEIFFLHLPSELERQDIFQVHLQRLRPTRLREFDLGVLAKRTENFSGAEIEQVVIDGLYRAFGTFVNGQRRDLTTEDVLRSIEDTVPLVAIARSQIEDLKRWAAQSGAKTASNDSQLIDELKRYSQRGRRDGFDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F556</accession>
    <name>A0A2G4F556_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type II/IV secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003325</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56841">
        <property type="protein sequence ID" value="PHX56841"/>
        <property type="gene ID" value="CP500_003325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SSE_N" evidence="3">
        <location>
            <begin position="72"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="235"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="667" mass="74387" checksum="F8F5D8EC2D82A5D4" modified="2018-01-31" version="1">MTNTSDRRFSTSLVATSLFTPALNKMIQSGYVNSDQLKKAQLESKKSGKRLTEVLESTTGLPLPPELLRLYKKQQMFEMKIVYGVEAFDPELSELTNEQLGAMLDDLKMSIDICHQRRFLPVAKTETEPPAIVVAMVDPDNLDAQEDLRRILKGLSFQRRVITPDDYQDITSVYQEDQVKIAAKIAEAEKERKLSLGDGDFGELSLEEVSADTEDIADTINAVEQAPVIKAVNIILAKALSEKVSDIHVEPQEEFMRIRMRKDGVLQEYFRFPKQVVQGITARFKIIANLDIAERRQAQDGRIRRVFEGRTVDFRVNSLPSRYGEKIVLRILDSSSTQLGLGLLISDPETLALVRETASRPFGLILVTGPTGSGKSTSLYSILAEKNDPAINICTAEDPIEYALPGITQCQVIREKDLTFSNILRAFLRQDPDVMLVGETRDKETAKTALEAALTGHLVLTTLHTNDAAGAIARLDEMGVEPFMVSAALLGVLAQRLMRRVCDKCRIPYQPTAIELGRYGLSASQEVDLTVYKANTIPVEQRKELAEQDKLCKKCGGIGYKGRVGVYEFLKNTERLQTLITQGAPTEQIKEAAVEEGMKTLLAYSLQLVREGATTFEEVERVTFTDSGLEAEMKAKRKQGLTCKTCQAELKPEMLDCPYCLTPRFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5M2</accession>
    <name>A0A2G4F5M2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_003985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56777">
        <property type="protein sequence ID" value="PHX56777"/>
        <property type="gene ID" value="CP500_003985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="639" mass="70333" checksum="D7B739E6C5805859" modified="2018-01-31" version="1">MQNSKYRILGLVGQGQFGRVYCATVRETPANDSRLTSQLVALKELSHQKAPTSEFLRELWFLITLQHPNIVTCRALEHTATGRYLVMDYCEGGTLRNLLKQDRPLRLLEGLQLIMGVLAGLDYAHRRGVVHCDIKPENILLTLGSKGWSPRLSDFGIARRLPEIGTTRLHQEISPDATVGSPAYMAPERFYGLYSPMSDIYAVGILLFELLMGYRPFGGTPGDLRWAHLNQRLQLPDAIPEPLQAIVKKSLEKLPARRFASASQMAQALRLVMYDPTVRQLGDWIIPWENQAERDSESLKSQETDSGLEVEDKKTSAPVINLHQAVSCSLSQPKPLILPAPLTVLVANETYLYAAASTEVKVWSGPGNQLLTGETQVSVSIPETVRGILPTSHGCCVLSSQKLYWLNDKSWEPQCLLDLGLSQGVDACKAAVDSDGRWLTVAVPGELRFYSLVANNTTGDREQALKPIATVPLPEHYLPELMFLDRRHVLAIWPDNEQKNPQTTFRVYTRRGTAVGAVRLSAIVGQVLLTPEPYTLLGIPQGGKAAVLLMKLWPLKVARIPLESFPVSACVANWGWVLADIGGQMVVLNTQGIQVGSFSGPAAPQAIVPWGSKGLVIAVNTSEGSHLHFLDVDVEETNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F675</accession>
    <name>A0A2G4F675_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phycobiliprotein ApcE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CP500_002560</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the phycobilisome linker protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56987">
        <property type="protein sequence ID" value="PHX56987"/>
        <property type="gene ID" value="CP500_002560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001297">
        <property type="entry name" value="PBS_linker_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038255">
        <property type="entry name" value="PBS_linker_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00427">
        <property type="entry name" value="PBS_linker_poly"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51445">
        <property type="entry name" value="PBS_LINKER"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="10" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="6" id="KW-0157">Chromophore</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="domain" description="PBS-linker" evidence="12">
        <location>
            <begin position="263"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="PBS-linker" evidence="12">
        <location>
            <begin position="534"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="domain" description="PBS-linker" evidence="12">
        <location>
            <begin position="729"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX56987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="922" mass="102229" checksum="20FFD015EF826AFD" modified="2018-01-31" version="1">MTVKASGGSSVARPQLYQTVPVATISQAEQQDRFLQRGELSELATYFSSGALRIDISATLTQNSELIVSRAANRIFTGGSPLAFLERPAEPVMAMAGATRGGSASVSEGMKLGTVTYVEGRAGKSSGGGGFLGLGNLFSGNGGYSGPLPAGFQPINVSRYGPGNMTKSLRDLSWFLRYITYAIIAGDPNIISVNVRGLREIIENACSSAATIVAMQEMKAASLGYFKKDSEATAIVGQYFDVAITEFKAPTPSPKVRQRESNDQQGLQLPQIYFNAAENRAKFVMKTGLSSAEKIEVIKAAYRQVFERDITRAYSQSISDLESKVKNGEISMKEFIRRLGKSPLYRQQFFEPFVNSRAVELAARHFLGRGLSSREEFSKYFAIVTKGGLAALVDAMVYSQEYSDYFGEETVPYLRGLGQEAQECRNWGPQIDLFNFSAPFRKVPQFITLFAGYTQPLPDQHVYGIGNDPLEIQFGAIFPKETRNPKNRPAPFGKDTRRILIRQGAGIDNQLSNPAARGNAPGSLGPKVFKLAQLPSSYVASKKTARGVSSSYSNASSVKFTESSTQAVIRAAYLQVFGRDVFDGQRQKVAEIKLENGDIPMREFIRMLAKSDVFRNMYWSKFYVCKAIEYIHRRLLGRPTYGRQEMNAYFDICAKKGFYALVDEMMDSLEYNEAFGEDTVPYERYLTPAGLSMRTMRSGSFGEKKANVEPTPETPRFIELGTASDAGDLQLQSRIAQGVSKRREQTKVFKLTTTSDKVALKTLIQAAYRQVFERDLNPYVVKNEFTALESKLGNNEINLKEFIECLGCSSLYVKQFYAPYPNTKVIELGTKHFLGRAPLNQAEIRTYNQILASKGIKGFINAMLLTVEYAEAFGEDTVPYRRFPTLPAANFPNTEKLYNQLTKQNGEIVVPSFEPATAIDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6C1</accession>
    <name>A0A2G4F6C1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57241">
        <property type="protein sequence ID" value="PHX57241"/>
        <property type="gene ID" value="CP500_000955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="434" mass="49341" checksum="79646BF0CB558845" modified="2018-01-31" version="1">MALPPGSFGLPLIGDTLNFLRDSQFAKKRHQQYGNIFKTSIFGQPTVFMCGQEANLFVLSHENQYFVVSWPPSTKALLGPLSLALQTGADHQNRRKLLYQAFQPRALAGYIEAMEDITQRYLEKWAQMSEFAWYPELRNYTFDVACKLLVGIDSGSEMPLGHYFKTWCKGLFSIPFDVPWTLFGKAKNSRKLMLAELEKIIRDRQQGIPGGNDALGLLISARDDEGNSLSVEELKDQVLLLLFAGHETLTSAIASFCLLVAQHPDVMAKVRAEQQQFPPTEPLTLEQLKQMTYLEQVLREVLRLVPPVGGGFRTVINACEFGGYEIPKGWSVLYQINQTHQDATVYPEPDRFNPDRFNSERSAKPFSYVPFGGGLRECLGKEFARLEMKLFAARMIRECDWELLPNQDLNLIRVPTPHPRDGLRVKFQRTTINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6D1</accession>
    <name>A0A2G4F6D1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fic family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_000570</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57310">
        <property type="protein sequence ID" value="PHX57310"/>
        <property type="gene ID" value="CP500_000570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="130"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="214"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for autoinhibition of adenylyltransferase activity" evidence="3">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="313" mass="35815" checksum="AA05ECE145EB06D5" modified="2018-01-31" version="1">METQLYEKFIQKVIILGKQKEFSLTSSIDNYLMMNYRLKLERIDKLKAWLDGFRPFDSTLVAELKKLYDVRFTYNSNAIEGNTLTQSETELVLTKGITVGGKTLDEHLEVIAHKEAIDYIENLAQKDTEINEWEIKQIHNLILRKINPEEAGSYRTLDVMAAGTNYRYPPHYLLSQLMRDFASWLNSESALNLHPVEYATMAHYRFVSIHPFRDGNGRSARLLMNLLLIRAGYPIVVIDNQIRNDYINALAYGQQNQDDLSQLFALIFDATISSLVEVLRLLVTASSSRGKGQAFYQEITDFLDRSGGLGNGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6G3</accession>
    <name>A0A2G4F6G3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferredoxin--nitrite reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57346">
        <property type="protein sequence ID" value="PHX57346"/>
        <property type="gene ID" value="CP500_000775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008990">
        <property type="entry name" value="Elect_transpt_acc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004207">
        <property type="entry name" value="Fd_thioredoxin_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044166">
        <property type="entry name" value="FTRV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46937">
        <property type="entry name" value="PTHR46937"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02941">
        <property type="entry name" value="FeThRed_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50090">
        <property type="entry name" value="SSF50090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeThRed_A" evidence="1">
        <location>
            <begin position="3"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8897" checksum="397D05E0ACB3BA88" modified="2018-01-31" version="1">MKVGDRVCIKNSVVVYHHPQNRNQPFDVKGMEGEIVAIVQEWHGRPVSANWPILVQFDKKFKTHLKEDEVELVSSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6I6</accession>
    <name>A0A2G4F6I6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57403">
        <property type="protein sequence ID" value="PHX57403"/>
        <property type="gene ID" value="CP500_000235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="12563" checksum="441D98A6813FC95A" modified="2018-01-31" version="1">MDRSLSYADILKQTLQEATRSQPRLQAIQLYPVCDTDSGHFLILAIGWDKQRWIDTILFHARLVDRHVIIEEDSFEEGLTPALIVAGIQPEHIMAGLDYQSDASPLVFEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6N1</accession>
    <name>A0A2G4F6N1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57375">
        <property type="protein sequence ID" value="PHX57375"/>
        <property type="gene ID" value="CP500_000065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8472" checksum="13F460CE4D3C2F59" modified="2018-01-31" version="1">MANLRTIAPEPQATELIELKEDSQIWASLKKAIGSSSGFQRWQLELNFESQQANVSIDQQVRSYLRETLETLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6T4</accession>
    <name>A0A2G4F6T4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57227">
        <property type="protein sequence ID" value="PHX57227"/>
        <property type="gene ID" value="CP500_000870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024499">
        <property type="entry name" value="Mbeg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11187">
        <property type="entry name" value="DUF2974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="455" mass="48987" checksum="FB1E07A5EAC60DB7" modified="2018-01-31" version="1">MTVSPAVYEVLAKSIVYLNDRPDSQNIVSRFLDTNGYYIDRIFDDQRTGFYAIGFGATDPQNPPVLVFRGTDFIGNDAIFADSRNIGFPEFENNKDAIDNWLKQIGTNYGQNPNLLLPDVIGHSVGGAIAQIVATESNLITGNIFTFNSPGVSKTTVNTFRRNLSITPNKTANHYIVSGDFVSLFGEAFLPGRAFIQTFTDPNIDPLIILAKQRSEKLLTNPPVGFFQRQISVEDLNSPEFTYNNDSDFNEFIAAMNFALPEVSIAIRTRAGAESLRTAPEFSFVGLIKEMQVGLAPLQANYLSGDDRNNAATGGGGDDTIIGNGGNDTLRGNRGNDSITGGGADDFLYGGRNNDYLNGDDGDDLIAGELGNDILIGGKGRDRFVLESGGGGDVIVDFEDSQDLIGLSRGLTFAQIRISQSADGALISIPITGEILATVMGVSVSDISRPDFVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUD8</accession>
    <name>A0A2G4EUD8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_023075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000263">
        <property type="protein sequence ID" value="PHX53144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53144">
        <property type="protein sequence ID" value="PHX53144"/>
        <property type="gene ID" value="CP500_023075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020360">
        <property type="entry name" value="Uncharacterised_alr2393"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17310">
        <property type="entry name" value="DUF5357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="332" mass="37745" checksum="ACE45A6E76BB43E0" modified="2018-01-31" version="1">MMKQFLDVTQQLTKLTNNLWEQNKKFQKALIPPKVVHWKTPLLISIFLALLSVAAVTDAPTRTTIADLSWLSFIISMGLLTSQPPFVIYGVSISPWVTSALIGLWLLVRLPPDSRHIAWIAGPLIAIVVLAAIEIWNSESKWERIKSLVKPQFLIITLIHVLFSCWFAFHFLIQGWLQQYPSVLSQNLKQSHYVVTFQGPKINPSRGVIILNEMEKYLNNQARTKPWPPIEQMLIDIDNERFFLKNEAFKKMRIVPEDASWDVKTSVVQGQSRYQLEMQATWLGLVFRPEIYSFTKSCEVINIGNAATVDCGAIKRSKPGLKKNGTAGDSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUZ7</accession>
    <name>A0A2G4EUZ7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein CP500_021905</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021905</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000209">
        <property type="protein sequence ID" value="PHX53363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53363">
        <property type="protein sequence ID" value="PHX53363"/>
        <property type="gene ID" value="CP500_021905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01033">
        <property type="entry name" value="TIGR01033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="254" mass="27537" checksum="563A2A87A58386B2" modified="2018-01-31" version="1">MSGHSKWATIKRQKARVDSAKGKVFARISREIIVAARSGVPDPAGNFQLRTAIEKAKAASIPSENIERAIAKGAGLSGGGSELEAIRYEGYGIGGVAILIEALTDNRNRTAADLREAFSKNGGNLGEMGCVGWMFDEKGVCTVRGSIDEEKLLEASLEAEAESYELISIDEDNEGAEVFTTVANLETLSDILKQKGFQVSQSETRWIPSMTVEMDNPEKARSLLKLMDALEDLDDVQSVTANFEMAEELMLLIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV09</accession>
    <name>A0A2G4EV09_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000207">
        <property type="protein sequence ID" value="PHX53373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53373">
        <property type="protein sequence ID" value="PHX53373"/>
        <property type="gene ID" value="CP500_021850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="7129" checksum="7712337965CD8E8E" modified="2018-01-31" version="1">MKFISSKSKNQMRRDRMSRIQIPINLLSQSRGRVNEAENKLLRRYSLSQKDEVLSGIGHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV14</accession>
    <name>A0A2G4EV14_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PBS lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_021835</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000207">
        <property type="protein sequence ID" value="PHX53374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53374">
        <property type="protein sequence ID" value="PHX53374"/>
        <property type="gene ID" value="CP500_021835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="163"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="44734" checksum="94A25B92CC37621A" modified="2018-01-31" version="1">MAIIGAIVGFLVGIAVAYSLVEKRLNKQKQEHLEQTRQIAEEIERSHQSRIQQTVQSLQVEQDNTLRKVTVEHEDALRQVTTEHENLLIKIIEDRDDQLREITNEQQNQIRESSAGIEQNHDSDLQENIQSLQQKHEAELLRLSEELHHNYQAQIDDNLQALQEKHEVRLREITEEYQNREVEMQFNLESLQEQYESQLQAVNEQLKAHETQMQATIKSLQEQYEGKLHQTEVPQQQFIDLPQTEVPQQQFIDLPQTEFIAPAQIVRQAPNYSLAQLMGFVQSQDAEARKLAASALGKIAAANPLRIDGQRGVETLGKLAQDSSPEVRQTAVEALGMIKSEKVIPLLQKALRDTDSDVVKSASAALNKFKFYRRIPAFKAKMIHGKKPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV49</accession>
    <name>A0A2G4EV49_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pstC</name>
        <name evidence="11" type="ORF">CP500_021920</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53358">
        <property type="protein sequence ID" value="PHX53358"/>
        <property type="gene ID" value="CP500_021920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="82"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="318" mass="33586" checksum="8EF763EFDEA4EFEB" modified="2018-01-31" version="1">MISDNNSSQSESRSRSEAEKSLDKGFIWLTRVLGIGIGVILLAIALTVAYRALPAIQQYGLGFLFSSSWNPVKEEYGALPMIYGTIVSSAIALLIAVPLGVGTAIFLSEDFIPLQIRTALVFLVELLAAIPSVVYGLWGIAVLIPIISNVGRFLNGTFGWLPIFSTPPVGPGMLPAGVILGIMTLPIITAISRDSLASLPPELRQASLGLGATRWTTIFRVLVPAAFSGIVGGIMLGLGRAMGETMAATLLIGNSNQLSASLLAPANTIASLMANQFAEASGLQVAALMYTGLILFILTLIVNILAEWIVSQVRAKYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV75</accession>
    <name>A0A2G4EV75_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_021470</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53434">
        <property type="protein sequence ID" value="PHX53434"/>
        <property type="gene ID" value="CP500_021470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="57"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="326" mass="36584" checksum="424D47EE6ED3A781" modified="2018-01-31" version="1">MPIILVEDLSKVYPIAIKEPGMKGTLQHFFKRNYRNVKAVDGVSFSIESGEVVGFLGANGAGKTTTLKMLTGLIYPSTGTVRVCDRIPFRRESDFLQKITLVMGQKQQLIWDLPVLDSLRINAAVYGICDRDYRQRVGELTEMLSLEGKLNQAVRKLSLGERMKAELMAALLHQPEVLFLDEPTLGLDINAQFSVRKFLREYNDRYQATVLLTSHYMADITALCKRVLLIHEGLLVYDGSLDGLLDRFAPYRQVQVELASPLSQDRASAYGEVESIEGQSVRFLVKREELMVGVAKMLAQLDVVDLTVTDPPIEEVIGRVFRTGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV87</accession>
    <name>A0A2G4EV87_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_021410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000195">
        <property type="protein sequence ID" value="PHX53453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53453">
        <property type="protein sequence ID" value="PHX53453"/>
        <property type="gene ID" value="CP500_021410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="87"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="283" mass="31183" checksum="D00D701F63BAE549" modified="2018-01-31" version="1">MINNFWLTIRRTCGRGIYLFLSLIVAVGIWVISPEPMQAFSLPELIFRGIQVIQLSNLSDRQEVAIGRQINQELAGKEFKIDTDRATTAYINRIGQRLAKESDRPNIPYTFQVVDDDNINAFATMGGFVYVNKGLMTAADNEAQLASVIGHEIGHISARHAIKQMRQMAIASGVASATGLDRSKAVQIGVELALRRPHSRQAEYEADQLGLQTMGRSGYAQSGMVDFMKKLLNKPSPPSILSTHPDTASRISAIEQGIEPDLATGEGLNNANYRQEIRRLLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVB2</accession>
    <name>A0A2G4EVB2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">16S rRNA (cytosine(967)-C(5))-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.176</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">16S rRNA m5C967 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">rRNA (cytosine-C(5)-)-methyltransferase RsmB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">rsmB</name>
        <name evidence="14" type="ORF">CP500_021355</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(967) in 16S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(967) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42748"/>
            <dbReference type="Rhea" id="RHEA-COMP:10219"/>
            <dbReference type="Rhea" id="RHEA-COMP:10220"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74483"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.176"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.176" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000193">
        <property type="protein sequence ID" value="PHX53469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53469">
        <property type="protein sequence ID" value="PHX53469"/>
        <property type="gene ID" value="CP500_021355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031341">
        <property type="entry name" value="Methyltr_RsmF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004573">
        <property type="entry name" value="rRNA_ssu_MeTfrase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17125">
        <property type="entry name" value="Methyltr_RsmF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00563">
        <property type="entry name" value="rsmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="13">
        <location>
            <begin position="282"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="129"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="373"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="141"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="494"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX53469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="554" mass="61592" checksum="DEC10745F8B19573" modified="2018-01-31" version="1">MQNPRQIAFLALREVHRRGAFADVALDRTFRNSELTDLDRRLVTELVYGSVRRMRAIDFIIDKLATKKSSQQPPELRTILHLGLYQLQYLNNIPPSAAVNTTVQLAKENGFSGLSSFVNGLLRQYIRVTPPTPPYQGGAKIAPNSPQQPETKTTSNPPPYQGGAKNNPNSPQQPETKTTSNPPPYQGGAKNNPNSPQQPETKTTSNPPPYQGGAKNNPNSPQQPETKTTSNPPPYQGGARGGLNPLKLPENLVERLGILHSFPDWIVEMWLDQLGETETEQLCQWFNQSPTIDLRINPLKSAIAQIETAFKSQNISVSRIPHLPQALRLNGSSGAIQNLPGYSEGWWTIQDSSAQLVTHLLDPQPGETIIDVCAAPGGKTTHIAELIQDTGTIYACDKTANRLKRLKENADRLQMRSIQIHTGDSRQFPEFINLADRVLLDAPCSGLGTLHRRADARWHHTPENIQQQSQLQSELLANAATFVKSGGVLVYATCTIHPLENEVVIQSFLDSNPNWQIEPPTMDLPVQPSPEGWVKVWPHRHQMDGFFMVRLKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVI3</accession>
    <name>A0A2G4EVI3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000178">
        <property type="protein sequence ID" value="PHX53553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53553">
        <property type="protein sequence ID" value="PHX53553"/>
        <property type="gene ID" value="CP500_020850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="795" mass="91895" checksum="02226E537C19F0BD" modified="2018-01-31" version="1">MSTPKSSSRQNNNNSVKSLMPADMDSTEQDNHNLQSEVNLEQLLQALVAGIPTQSAEIEQLETWKKDLQWVFQFLGNRRVLIAVIEPGTFALRYANAAFCRLAGWEGTPLGSGEIGGLFAGMGITLLELFEEWDQKTAEKLYRRHLLHWVFKQSYQIDLGVLRVLDEPVMAGVKNRLQPELRFVEFWLGSEQLKITRIDQKIDEFADLHLQSMPVSEREAWLMQPNQLAILADRLQLDNYQVEGLLVLEGFDVSVQEQIRRLTQLLIDRDSMLRPDKFERIDGCLRSLFNADGTLLLRPDGEQVQILVAKGGEQLPPVVYAMNSLEASHFLKATTANQVWNVPDLRRECDTECDRALRKMGVRSMLLVPLVVKTVTREGCVQRILGVVGLLCDRPNHFNGIDSQHAQELIPAFIAALRQAMQQRFSHIHNIHPAVEWRFVQEAERRSWGLKQETIVFTEVYPLFGISDIRGSSDERNRAIQTDLLEQFRLALGIVDAVCETKKTHFGQQLRLDLLDYIEHLKEKVTVDMEVRAAEYLNEHLEVYFDYFLQCGPKVQEAVEAYRVACENEHNCVYCDRTRYDEMLHLISTKLQETWVLWQERMQQILPHYCDIECTDGMDHMIYVGKSIDTRFSQFHLHSLRYEQLRAICDCGRTVFRLKAESQINMELVHLVLVQNTTIDIFHNENTEKMFDVKGTRDIRYELVKKRIEKAVDQDAKERITQSGMLTVVYSTEDEWEEYEQYLRYLSREGWVESKVQTGMVESLQGVSGLKFARVRILPEPESIVHIAEVTVVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVJ6</accession>
    <name>A0A2G4EVJ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_021170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000188">
        <property type="protein sequence ID" value="PHX53498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53498">
        <property type="protein sequence ID" value="PHX53498"/>
        <property type="gene ID" value="CP500_021170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PHYTOCHROME_2" evidence="3">
        <location>
            <begin position="48"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="218"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="292"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="345"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="412"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="497"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="575"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="702"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="794"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="869"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="1134"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1394" mass="157633" checksum="9810E817AE6ECDEE" modified="2018-01-31" version="1">MFPEFLYQEVTSLRMKIIHLEKEMQSQTWFKKLQALMGVIGKIRESLDLETIFKTTATEVRQLLNADRVAVYRFIPESDWNEGEVVSEDVLPQYSPSLGTKVHDHCFGEQFAANYEKGYVQAVTDIYKAGLSPCHLSILKRFQIQANLVVPLLQGKHLWGLLCIHQCGKPREWQPDEIEFAKQIGEHLAIAITQAELHLQTQRQLAEIDRTQQQLRESEKRYHQILDSIADMVLVKGPESKILWANQAFRDYYGMSEEELQGIVDAPLANPDNTRPYIKDDSFVFETGQTLQIPDEPVVRHDGEVRLFSTVKTPIRNAEGEIAMTVGISRDMTERKRSEEALQASETQYRRLVETSQDMIWSVDTQGCFTFVNPAVKYIYGYDAEEMLGRHFSDFVVPEQLPKDLEAFARLMTGESIVVRHESVQIAKDGSLKNLMFNAIALYDDTGNILGITGTATDITDRKRAEAALQHAKAELERRVEARTAELRQTFAALSASESRFRTIAATIPGALFQFASRDGVWRMDYMSDRIFEISGITAAEITQDINIFISRIHPEDFDGFLVSVNEVVDNMSVWHYEGRLIKPNGEICWWQGDSVPTRNENGEIVFCGVLIDITDRKLAETAIRDSQRQLQEAQRIAHVGNWELDATTGTVTWSEELFRIFGLEPAATAPTREQQVAQIHPEDLELWQTEVHRGVDFGIPFDFDFRLYRPDGTLRHLNSVGKAETDANGKVVKLLGTAIDITDRKNAEAALRQAAAQLEDRVDDRTAELWQAVAQLELEISDRKNAEAELQHAQKFMESVLQTIPVGVVAKEAEELRFVLWNPAAEELLGFPAAEVMGKNDYDFFPREEADFFTAKDREVLASGQILDIPEEQIQTGEGEERIFHTKKTAILDREGNPQYLLAVTEDITDRKRGELALRESSAQLRQQADREKLLNTLTTQIRNSLDFDSIISVAVQEIRAFMQIDRCYFSQYRIEQEEAFWEIIQESRTRELPDLIGCYKASDFGTLGEQMLRLETLQIDDIGAITDPIWRQSLSSMGYQSVLAIPMQALSGVVSVITCAHSAAVRPWSQSEVELLQAITVQLAIALNQADLYTQTVNKARELEQTLQKLTSAQSQLIQGEKMSSLGQLVAGVAHEINNPVNFIYGNLSHANEYTQDLLNLIELYQKHYPEPVPEIQAEVENIELDFLMEDLPKLLTSMKVGADRIQQIVASLRTFSRMDEAEMKAVNIHDGIDSTLMILQHRLKAKHNQAEIPLIKQYGNLPLVECYAGQLNQVFMNVLSNALDALEERDLRRSADEMRQNPSTISITTEMPKPDRVIIRIADNGQGMSETVRNRLFDPFFTTKPVGKGTGMGLSISYQIITDRHGGSLECTSSPGNGAEFAIEIPLKANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVK6</accession>
    <name>A0A2G4EVK6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4258 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53573">
        <property type="protein sequence ID" value="PHX53573"/>
        <property type="gene ID" value="CP500_020745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025354">
        <property type="entry name" value="DUF4258"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14076">
        <property type="entry name" value="DUF4258"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="12398" checksum="9DA611435BFCA8D0" modified="2018-01-31" version="1">MNLNDIIEAILENRVRITDHADEEAENDRLSFDEIYFSVFYGEIIENYPKEKPYPRYLIYGESFRGDPIHSVWSYVPSNKLAILITVYRPDANRWINWIKRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVL5</accession>
    <name>A0A2G4EVL5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YgiT-type zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53574">
        <property type="protein sequence ID" value="PHX53574"/>
        <property type="gene ID" value="CP500_020750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022453">
        <property type="entry name" value="Znf_MqsA-type"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03831">
        <property type="entry name" value="YgiT_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="86" mass="9480" checksum="C532CB37594BFD47" modified="2018-01-31" version="1">MLSVEKCPICGGEIVIKEVDKLLRGGNHTAILKVSAEVCLSCGERLYSVETVRKFAKIRQQLQREETQEFQPMGQSFRVGLSAPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVR5</accession>
    <name>A0A2G4EVR5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000168">
        <property type="protein sequence ID" value="PHX53642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53642">
        <property type="protein sequence ID" value="PHX53642"/>
        <property type="gene ID" value="CP500_020395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="44"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="301" mass="33208" checksum="B222C28A2709472E" modified="2018-01-31" version="1">MTQTTDLTKSNSGNYSAAVQEYLWNWKETQIKVVYETRGQGTPVLLLPAFSTVSTREEMRPLAEILAPNFQVVAVDWPGFGDSSSPRIDYEPQLYHQFLTDFVESIFNTPVAVIAAGHAAGYVMALAQSKPNVWSKIVLAAPTWRGPLPTMSKQQSGWHGIVRELVRSPILGQFLYKLNTAPSFLSFMYRRHVYADPAKVTPDFIQNKWQVTQQPGARYGSAAFVTGGLDPAKVRSEFTDNFQQLAVPVMVVIAENAPPKSKAEMEVLAELPGVESRVISGSLGMHEENAGDLANAIKSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVR7</accession>
    <name>A0A2G4EVR7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_020360</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000167">
        <property type="protein sequence ID" value="PHX53652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245909">
        <property type="entry name" value="M.Tbo703ORF20360P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53652">
        <property type="protein sequence ID" value="PHX53652"/>
        <property type="gene ID" value="CP500_020360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="387" mass="43619" checksum="9ED1BBA686295867" modified="2018-01-31" version="1">MNSLELFSGAGGLAKGLELSGFKHSALVEINKNAYASLCANFDTEKIFFGDIREFNLEMLGNIDVVAGGPPCQPFSVGGKHKADRDSRDMFPYAIDIIKNLKPKAFIFENVKGLLRQTFADYFEYIILRLTYPSITAETNSDWLQHLGELRNVSQLSYSGTKYNVQFKLINAANYGVPQTRERVVIVGIRSDLKSFCSFPPETHSSDRLFWDMYITGEYWERHKISKSNRPLMDKLIENKVFKLKDQYGMFAPVFRPWQTIRDALDDLPDPKSNHGINDHVFRDGARIYPGHTGSTLDLPAKTIKAGDHGVPGGENMIRFPNGSVRYLTVFEAKRLQTFPDHFVIKGPWGEAMRQIGNAVPVLLAEKIGHELVKTLNAHNRLVGCVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVS1</accession>
    <name>A0A2G4EVS1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">def</name>
        <name evidence="3" type="ORF">CP500_020720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53568">
        <property type="protein sequence ID" value="PHX53568"/>
        <property type="gene ID" value="CP500_020720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="186" mass="20794" checksum="AF70D9AB4146893C" modified="2018-01-31" version="1">MTAQVLVEKKKLEKPPLTIHTLGDRVLRQPAKRVKSVDAEIRQLVREMLQTMYSAEGIGLAAPQVGVNKQVIVLDCEPDNPATPSLVLINPTIKNTSGELCILQEGCLSIPGVYLEVKRPEFIELSYRDEYGRPQTLKATELLSRAIQHEMDHLNGVLFVDRVENKLALNEELVKNKFSPKAVKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVT8</accession>
    <name>A0A2G4EVT8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_020405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000168">
        <property type="protein sequence ID" value="PHX53643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53643">
        <property type="protein sequence ID" value="PHX53643"/>
        <property type="gene ID" value="CP500_020405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="4">
        <location>
            <begin position="74"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="392"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="604"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="632" mass="67255" checksum="8396FC6E79A03997" modified="2018-01-31" version="1">MYLVKHLQIKKGLTPWVSGLLATSLIAGGGYIAYSQLTVQSKRESRRKEKTVAVERVNLPIAISANGTIVPERSVNVSPKTSGVLKTLLVKEGDTVKTGQILAQMDDSNLQGQLTQNRGQLASAEANLQKLLNGNRVEDIAAAKAQLAEQQASLEKLLNGNRTQDIAVAQAQVTEQQATLQKLLNGNRSQDIAVAQAQVTEQQATLQKLLNGNRSQDIAVAQAQVTEQQATLQKLLKGNRPEDIAQAQAKLRDAEYAKNQASEDFQRNQELYTAGAIGLQIVNTSRTARDRAQTQVRQTQQALALLQAGSRPEDIASARAALEQKQQALALIQAGARPEDIAAGRAAVEQKRQALAVVRSGARSEDIAASQAAVEQKQQALALIEAGARPEEIAQARAQVLSAKGSLQTVQALINDTRIRAPFSGTVTRKYADPGAFVTPTTAGSAVSSATSSSILSLASKNQVVANVAESNIAQIRLGQGASIQADAYAGKTFTGKVIQISPQSIVQQNVTSFEVKTSIVDDTKKMLRSGMNVNVEFKAGELKDVLVVPTAAIVRQRKETGVYVTGGEDGKPLFVPIKTGMTVDDKTEVRSGLKGNEQVFISFPPGLRPKSQSPSPGGIPGLQPGGGTRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVU5</accession>
    <name>A0A2G4EVU5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_020615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000174">
        <property type="protein sequence ID" value="PHX53598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53598">
        <property type="protein sequence ID" value="PHX53598"/>
        <property type="gene ID" value="CP500_020615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="5"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="20590" checksum="1973D7F4B25A31FD" modified="2018-01-31" version="1">MAGQKILVIDDSKVIRVRVREMLPQGNFEVLEAKDGEEGLKLIRQARPNLIMLDFLLPKVSGWEVYQKVQAHPELSKIPLVIMSGREEEVMEKIPKPFENHFFAFIAKPFEKKQLTEAIKLAMVLAKKKPVPEVPPTTAAPTSGSGTAELEAMTQKMAKMQAEIDALKKQMSQVITIIKQKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVV0</accession>
    <name>A0A2G4EVV0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000163">
        <property type="protein sequence ID" value="PHX53682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53682">
        <property type="protein sequence ID" value="PHX53682"/>
        <property type="gene ID" value="CP500_020210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SH3b" evidence="1">
        <location>
            <begin position="58"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14580" checksum="2892AF208212E0A6" modified="2018-01-31" version="1">MLSFTQSKAFFIAAAIATFGFSLYSFPVFGKEQTLTPEKVEALKKQTVCSFINIKSGTVNIRKGPGNQHLVVAKLKRGDGVRAVSRQGNWVKIAARFSGNPPNETFTILDGWVNNQYINGCSEDQFDTWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW44</accession>
    <name>A0A2G4EW44_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000162">
        <property type="protein sequence ID" value="PHX53686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53686">
        <property type="protein sequence ID" value="PHX53686"/>
        <property type="gene ID" value="CP500_020135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="14655" checksum="F6FE978DF1591D31" modified="2018-01-31" version="1">MAIEQYRQYIRHLLSERQERASIQRNAQEYEVQTLFDAEQDHYQLLYVGWRGNKRDFGCVLHLDIKGGKIWIQHDGTEVGIANQLVELGVPKEDIVLAFHEPEVRQFTDFGTGEDIREQSPSVLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW66</accession>
    <name>A0A2G4EW66_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Transketolase</fullName>
            <ecNumber evidence="3 8">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tkt</name>
        <name evidence="10" type="ORF">CP500_021560</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="NXIB02000199">
        <property type="protein sequence ID" value="PHX53427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53427">
        <property type="protein sequence ID" value="PHX53427"/>
        <property type="gene ID" value="CP500_021560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="9">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="671" mass="72639" checksum="833154D50F7ADEB5" modified="2018-01-31" version="1">MAVATQPLEELCINSIRFLAIDAVEKAKSGHPGLPMGAAPMAFVLWDRFMRFNPKNPKWFNRDRFVLSAGHGCMLQYALMYLTGYDSVSLDDIKQFRQWESKTPGHPENFVTEGVEVTTGPLGQGIANAVGLAMAEAHLAAKFNKPDNTIVDHYTYVIMGDGCHMEGISGEACSLAGHLGLGKLIALYDDNHISIEGDTNLAFTEDVGKRFEAYNWHVITVDNDALDQDTSIEAVHKAIEEAKKVTDKPSMIKVRTIIGYGSPNKRNSYSAHGAALGGAEVQATRDFLKWEYEPFVIPDDALAHFRQAVDRGAQSEQEWQQAFDAYKAAYPAEAAEYERTVAGQLPEGWDKVLPTYSPEDKADSSRNHSGKCLNALAAVLPELIGGSADLASSNMTLLKGEKDFQKGQYEGRNLRFGVREHGMGAIANGMLLHGGLIPYCATFLVFADYMRGAIRLSALSEAGVIYVMTHDSVALGEDGPTHQPVETIASLRVIPDLLVIRPADGNETSGAYKVAIESRTRPTLMALSRQNLPNLAGSSIEGTAKGAYILSDDGGTPDIILIGTGGETYLCVDAAEKLRAAGNKVRVVSMPCWELFDLQDAAYRESVFPKAVTKRLAVEAAVSFGWGRYLGSEGDSISIDRFGASAPGPVVLEKFGYTVENVVAKAQALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW67</accession>
    <name>A0A2G4EW67_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HDc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_019665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53769">
        <property type="protein sequence ID" value="PHX53769"/>
        <property type="gene ID" value="CP500_019665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011624">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_extra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011621">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_intra"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07698">
        <property type="entry name" value="7TM-7TMR_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07697">
        <property type="entry name" value="7TMR-HDED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="503"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="555"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="HDc" evidence="3">
        <location>
            <begin position="613"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="853" mass="93079" checksum="7C4EFA4FF1AA731D" modified="2018-01-31" version="1">MRHIEQLGAARSLRQHTAKVKNDSKTEKPVSAALSREDRPRGSLLNLFSLKKFDRPDSFTPCKYKTSKSYLKNQARSPVLALVAVISLSSTLGHRFYNQPKLDVGTKAPETIKAPASANVPDLKTTEEQRKAARIGAVAILMVDSIADRQIYQELQQFLQQGSELRKAIGRWPLARAEALSIDVQSYLRSCPEWEWRSILAQVGDGSATSGVLSLESPAIAKPTRNQPQQDAVAQLQAYSRSVSTADFKQLTDAISEARQGYLKALDALSTKSVPRLGQIYDTSLFDLSETAWKETQMGMTKAAKRMLAQGIPQGLPKDILKEAVRLQVADSVPVASQALAVEALTAILQPNLVPDSEETKQLAELAAQKVKLVTIEVDPGEIIVREGKEISQQDFVLLDYFGLSRRGVNWLGLAGFVCLVGVAIAIVLLVERHYRLRRRDHLLLLLLTLSAPVLVSLGLPWTSLPAIGILASGFYGSAVGVSVVGLLSVVLPIGLELDLTHLVASAAAGLLGAVMAGRLRSREELALLGVAIGLTQAIVYLVATMIASAATGSIWYVLLGAVGSQGLAGLAWSVVALGISPYLEHVFDLITPIRLAELANPNRPLLKKLAAEAPGTFQHTLFVASLAEAAARELGCNVELVRTGTLYHDIGKMHDPIGFCENQMGGGNKHDEINDPWASADLIKKHVSEGLVMARKHRLPKAIQAFIPEHQGTMLIAYFYHQAKQIVAQEPTDSKIALANGHNLTTTLTIPSREVREKDFRYDGPIPQSRETGIVMVADSCEAALRSLKDATHEEALSMVNKILRARWQDNQLIDSGLTREDMSLIAEIFVRVWEQFNHKRIAYPSAVFTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWF9</accession>
    <name>A0A2G4EWF9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">APC family permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019045</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000143">
        <property type="protein sequence ID" value="PHX53892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53892">
        <property type="protein sequence ID" value="PHX53892"/>
        <property type="gene ID" value="CP500_019045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="611" mass="66683" checksum="22774C311A05F0F5" modified="2018-01-31" version="1">MYTYSRLKRVLLGKSLPTSASIHERLSNATGLAVLASDALSSVAYATQETLLVLLLAGSSSLSLSLPISGIIILLLAIVALSYRQTIKAYPNGGGAYIVARENLGIYPGLIAAASLMIDYILTVTVSISAGVAALTSAVPGLQFYTVELCLVFIVLIMFANLRGLRESGNIFMVPTYAFIVGIFILIGTGLYQQATGHVLPTLENIPAKEPLGLFLIARAFAAGCTALTGVEAISDGVLAFKPPEWKNARLTLTYLGVILGVMFLGISYLAHIYQVIPRENETLLSVLGKDIFGVGIFYYYLQAATLLILLLAANTSYADFPRLCYFLARDGFLPRQLSLLGDRLVYSNGITLLSLCAAFLVIVFRGDTTAVIPLYAVGVFTSFTLSQSGMVIHWFKERGKGWQLSAVMNGIGAVATTLVLTVIVATKFLLGAWVVVVTIPIVVSLFLAISRHYRYVAARLSIQGVEPKFYPPRPKVKVATHPAVVLVGQLHRGTLEALDYARLIADEVVAVHVDIGLTDREKLQAYWQNLHSDIPLEILESPYRSVGEALTHFLTLFEEQRPGVFLTLIIPAFVTRNWWEGLLHNQTAFFLKAALRAKRSRVVTTVRYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWI9</accession>
    <name>A0A2G4EWI9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Group 1 truncated hemoglobin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53922">
        <property type="protein sequence ID" value="PHX53922"/>
        <property type="gene ID" value="CP500_018870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="179" mass="19260" checksum="846CFEDD19C97FCA" modified="2018-01-31" version="1">MKFSKSLGILLTLVCITVIVVTTFRLSPSFARSTPAMPAQVSAEKVTTDLMAQVPAGNSLYTRLGGYNAIATVIDDAANFIFNDPLIGKYFIGLSTNSKQRLRQLLVDQFCQAAGGPCVYTGRTMKLSHSGMGGGLTNSEFNAFANGVSQAIDKNRVNQSEKVEVLAFVNSLRSKIVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWV7</accession>
    <name>A0A2G4EWV7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidinol phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000168">
        <property type="protein sequence ID" value="PHX53647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53647">
        <property type="protein sequence ID" value="PHX53647"/>
        <property type="gene ID" value="CP500_020400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046249">
        <property type="entry name" value="DUF6282"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19799">
        <property type="entry name" value="DUF6282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="327" mass="35894" checksum="B222074BB8CAA6B5" modified="2018-01-31" version="1">MNLCRFFTLKFLVITTAFLISWLSFSLPVYAVGYPHFPDSPKSTIESAIDFHIHSSPDVIPRRLDDFQVAKLAARAKMKAVVLKNHFASTAARAVLVNKIVPEIQVFGGVVLNHSVDGMNPQAVEAMHRIGGKYGKVVWLPTVDAECHLRVFHKPGIGIKVAENGKILPETEAVLEIVARENLVLETGHISPEEVMAVVEQANLLNIKNILITHAMADVPGLSLENMQTAAQMGAFLELAFVNDLMGENAADEGHKNRHHVSMSQMAAAIKLIGAEHFVLSTDLGRKPDPLPAEGYTIFVKKLMSEGISQREIDLMMIENPARLLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWW7</accession>
    <name>A0A2G4EWW7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000135">
        <property type="protein sequence ID" value="PHX53968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53968">
        <property type="protein sequence ID" value="PHX53968"/>
        <property type="gene ID" value="CP500_018655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="152"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="456" mass="51865" checksum="E46B5342B410ECE9" modified="2018-01-31" version="1">MLKEALNLANKIVFEKTGQHLDDLQAAVLRGTLERETYKHIAKDFDCSESSVRKVGAELWEILSEELGEDVSKSNLRSAIERLQVSLFSSNVAQDSVQIRNINYCGQGRHPPDISNSDNDEKYNPQQTKTLHQDLSEMPELGTFYSRTHELQTLTTWILQQNCRLITLTGISGIGKTSLAVQLVQQIKHEFEYTVWCTLDEFPTIDKFQSNLRQLFSQSENPDSSPTNQKRLPLIKYLQNHRCLVVLDDVHNLFCSGELAGKYKPDYEEYRSLLKQIEKLSHQSCFLLIGWEPPKEVPQLTSENTPIRTLQLTGLDTAAAGEILRDKGLAETDNCETLIHRYQGNPLWLKSVATLMQELGIGATELLIDDTILLPEDLKDVLDEHFDRTSELEKQVLSLLATENHPVNFAKLLQNRQISSSDLLNALQSLSRRCLIEKQESLYTLSPVLKQYIKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWX5</accession>
    <name>A0A2G4EWX5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000131">
        <property type="protein sequence ID" value="PHX54034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54034">
        <property type="protein sequence ID" value="PHX54034"/>
        <property type="gene ID" value="CP500_018350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="104" mass="11893" checksum="05E0DBEBD88B43BE" modified="2018-01-31" version="1">MAILEFLLVIGLSGFVGLFIVNNLNESKKKRQLDEAFYQLLEKQNSKISLIQLAASARVEAKVAQQYLDLQVKIFSAILEVDDEGDTFYRFPRLRLPPSSSQEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX27</accession>
    <name>A0A2G4EX27_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54081">
        <property type="protein sequence ID" value="PHX54081"/>
        <property type="gene ID" value="CP500_018065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="942" mass="94606" checksum="FA988FF2C19C323A" modified="2018-01-31" version="1">MPTPTPAPIPTPTPAPIPTPTPAPIPTPTPAPTPAIITVTNSNDSGAGSLRSAIASAAAGDTINFASSLASQTITLSSGQLLIDKSLTIDASGAANLTISGNNASRVILTQSSTNVTLKNLIVANGKVSGTDPNNEVTSAGGGIQTGGNSTLTLENCQVNNNVAGYAGGIYAGFQSTTNVTNSTFTGNDGRSANSERGGGAIGTKSGGSLTVKGSTFTNNKGINGGAINHLLGNLTVENSTFLNNDSTAGTGQNTSGYGGAIYTDGANASGANSTPGPVGGTIAIRNSRFEGNKGAGQGGGMFLFVYPPDKIIIEGSTIVNNQVVKSSNGDALGGGVRIGNGEFTISNTTFSNNLAQSQGGALWVGEKSPGTIVNSTFAENKAEDSSGKSGLGGAITLNTSESISIVNSTIAKNSAGFQGGAFWGGGSETTLKNTIVANNTANNGGNSWNIKQNAGSSKFSDGGGNFQWPAKNPNDSSDFNVTDSVTIADPKLDVLQTINGFSVMPLLAGSPAIDAGTGAGAPATDERGQTRLDGDSNGSIIADSGAYEFNGTVTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPIPIPTPTPTPTPSTDDCLFRTSAPEFNSATMIPNATQQTLKGDDTGNFIMGGSQNESINGLAGNDTLYGMGGNDNIDGGADNDSIFGNEGTDFLQGGSGNDIIYGGKDNDIVLGGEGDDFLKGDFGKDTVVGGLGNDTIFGGKDDDILLGEDGDDYILGNLGNDTINAGNGNDSVFGNEGADLLFAKAGNDTLYGGKENDSLDGGEGNDLLFGGNENDVICGDIGNDTLYGGKGNDILSAGAGSDFLSGDIGDDTLTGGSGNDVFFLNQSLGSDIITDFRKGEDLIGLNPGLSFNQLSITSSNNQTLISVTDSNQLLAKLNGVAANTLTASDFITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX84</accession>
    <name>A0A2G4EX84_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">hisC</name>
        <name evidence="6" type="ORF">CP500_017670</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54155">
        <property type="protein sequence ID" value="PHX54155"/>
        <property type="gene ID" value="CP500_017670"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="5">
        <location>
            <begin position="25"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="348" mass="38295" checksum="897467795450FB37" modified="2018-01-31" version="1">MNYFRKSIHEMSGYIPGEQPPLGSKIIKLNSNENAYLPSQKALKVLREIDGEMLRRYPDPTAKQFRLVAGQVLGVPDDWIVVGNGSDDLLNLIVRAVGETGKQVVCPSPTYVLYRTLAEIQDAEFLEVPYPDDYQLPVDLLIAAQGAVTFVASPNSPSGTAISVADLDKLAKGLSGILVIDEAYVDFAENNALELTKKYNNVIVLRTLSKGYSLAGLRLGFGIANPALIAELNKIKDSYNVDALAYLVGAAAIADQNYKTANAEKIKASRSKLALSLKELGFDIWPSQTNFLLVRPPNGDSERIYQRLKVEGILIRYFNQPRLADKLRITVGTEEQNQILIQTLKGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXR7</accession>
    <name>A0A2G4EXR7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4168 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54332">
        <property type="protein sequence ID" value="PHX54332"/>
        <property type="gene ID" value="CP500_016795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025433">
        <property type="entry name" value="DUF4168"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13767">
        <property type="entry name" value="DUF4168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4168" evidence="1">
        <location>
            <begin position="58"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="163" mass="17656" checksum="BE6C53BF088E4458" modified="2018-01-31" version="1">MNTSLNTCKFKFNQILRQSLLGSILSAAALASGWVPGLYANSPIPVFGAAAQAQEISNLEITNYARAVLAIEPRREAASREIKSMASGQAPKVLLCKAEGINSLSRNIRGVAVNYCDQAKKIIENNKLTISRFNQITVLQQGNPAVKAQIQAELMRLQQSGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY24</accession>
    <name>A0A2G4EY24_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">APC family permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_016380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000104">
        <property type="protein sequence ID" value="PHX54386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54386">
        <property type="protein sequence ID" value="PHX54386"/>
        <property type="gene ID" value="CP500_016380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="AA_permease" evidence="6">
        <location>
            <begin position="44"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="521" mass="55773" checksum="7FB32CEE237BA601" modified="2018-01-31" version="1">MTNSNGELKPTLGLVGITINAMALIAPGAFLWTTYQLQAPPDSAKNMWAAIALATCIALLTASCYATLSKAYPEAGAGSSYYYAEAAILAKEEHKHFRLARLAKFVTGWAAHLYYWVYPGIMISFMGTLVVYIGQLFNADFATDWFSKALICFIFTGLVGFIALQGVTGSTLINIIINIVQISSLTFLGLLMIIYRLGHPNVNYEHANAFSVVMPHDLSGLIYQATIAILLLVGFESATAMAGEAINPQRDIPRGVILSLFIQACICYFFEYFAANFFIGDQYTATVDGKTVTGFAAALSSGAPIGDIAKILGDSLLFGNGFLLQITIASTVVMALIGTALSSLSTGVRISYAMGSDRELPAVFGFLHGRYNTPHIGIYFLSGLSALIGAYAVQSVDNVTIVTLVSNIGTFMLYGITCGVTLIATLEHLLDEEHNPIKTIVIPVLGLVTNLFMVCGIFYYGLTGVGNAKTNSLTAIGISLAFFVGGFAYLIGDSLIKGKPLFLPSDLNHPMRDGIPSSKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY38</accession>
    <name>A0A2G4EY38_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="8">CMK</shortName>
            <ecNumber evidence="2 8">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ispE</name>
        <name evidence="11" type="ORF">CP500_015985</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="2 8"/>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54455">
        <property type="protein sequence ID" value="PHX54455"/>
        <property type="gene ID" value="CP500_015985"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="9">
        <location>
            <begin position="92"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="10">
        <location>
            <begin position="217"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="316" mass="34180" checksum="5F9728CECBB14D39" modified="2018-01-31" version="1">MRSYSLLASAKINLYLEIIGDRLDGYHELAMVLQSIDLVDRIDLRAIGTDTIRVRCDHPQVPPDKNNLAYRAADLLAKQFPDALAKYGGVEIAIHKQIPVAAGLAGGSANAAAVLVGMDLLWQLGLTQSELQELGGTLGSDVPFCIAGGTALATGRGDQLSPMPDCGPLYVVLAKFRNLSISTAWSYQTYRQQFSSSYCAPEDLDCRRERLHSGPMVGAIAQKDRSKIGQLLHNDLEKVALPVYPQVLQLREAFDSAGVLGTMMSGSGPTVFALAESQERAEEVQERVKSAIASPDLDFWVTKFSNTGIRIVSDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY50</accession>
    <name>A0A2G4EY50_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetolactate synthase small subunit</fullName>
            <shortName evidence="8">AHAS</shortName>
            <shortName evidence="8">ALS</shortName>
            <ecNumber evidence="8">2.2.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid synthase small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_016325</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Dimer of large and small chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54408">
        <property type="protein sequence ID" value="PHX54408"/>
        <property type="gene ID" value="CP500_016325"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="PTHR30239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="18857" checksum="E6FAD6E57C4A6E1B" modified="2018-01-31" version="1">MKHTLSVLVEDEAGVLTRIAGLFARRGFNIESLAVGPAEQVGVSRITMVVPGDDQIIEQLTKQLYKLINVLKVQDITEIPCVERELMLLKVNAATGTRSEIIELAQIFRARVVDIGDDTLTLEVVGDPGKMVAIVQVLNRFGIKEIARTGKIAMTRESGVNTEFLKSLEAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY73</accession>
    <name>A0A2G4EY73_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hybrid sensor histidine kinase/response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016120</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000101">
        <property type="protein sequence ID" value="PHX54436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54436">
        <property type="protein sequence ID" value="PHX54436"/>
        <property type="gene ID" value="CP500_016120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="173"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="423" mass="47396" checksum="6CEB199424BCC078" modified="2018-01-31" version="1">MSTNQKYILVVDDNPTNLAVISQALKTAGYKLRVASEGEEALTMMERCATLRSGQTLPELILLDVQMPGIDGFETCRRLQANPATKGIPVIFMTALTDAESKVKGLSLGAVDYITKPFEREEVLARVKVHWRLKELTDRLEQEVAERTASLQHTQLQLIQQEKLSTLGQLVAGVAHEINNPLSFVVGNIAPAKEYLADITELLNLYQQHYPQPVTAIADQINKIDLEFALEDFAKILDSMQLGTERIQDISLSLRNFARSSNDVRIKTDLHQGMDSTLMLLKHRLKDQGDRAKIEVIKHYGNLPEVDCYPGPMNQVFMNLFANAIDALEEAWEKDRRFLKIQIDTEVSERDTIIIQIADNALGMTENVRQNLFKPLFTTKTLGKGTGLGLSIAQQIVVDKHCGKLLCQSTPDKGTEFRVEIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYE3</accession>
    <name>A0A2G4EYE3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ketol-acid reductoisomerase (NADP(+))</fullName>
            <shortName evidence="8">KARI</shortName>
            <ecNumber evidence="8">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid isomeroreductase</fullName>
            <shortName evidence="8">AHIR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ilvC</name>
        <name evidence="12" type="ORF">CP500_017490</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000117">
        <property type="protein sequence ID" value="PHX54187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54187">
        <property type="protein sequence ID" value="PHX54187"/>
        <property type="gene ID" value="CP500_017490"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00435">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014359">
        <property type="entry name" value="KARI_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="PTHR21371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="IlvN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000116">
        <property type="entry name" value="IlvC_gammaproteo"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8 9" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="8 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="10">
        <location>
            <begin position="2"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="11">
        <location>
            <begin position="183"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="25"/>
            <end position="28"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX54187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="331" mass="35940" checksum="E0F4D5E477FB0433" modified="2018-01-31" version="1">MARMYYDTDANLDLLANKTIAIIGYGSQGHAHALNLKDSGMNVIVGLYPGSKSAAKATAAGLTVHPVDKAAAAADFIMILLPDEVQKTIYKEQIEPHLSAGKVLAFAHGFNIHFGQVVPPADVDVVMVAPKGPGHLVRRTYEQGEGVPSLFAVYQDASGQARDRAMAYAKGIGGTRAGILETTFREETETDLFGEQVVLCGGLSALIKAGFETLVNAGYQPELAYFECLHEVKLIVDLIVEGGLATMRDSISNTAEYGDLTRGPRIVTDETRAEMRKILSEIQSGQFAREFVLENQAGKPGFIAMRRQEAEHPIEEVGKDLRAMFSWLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYI2</accession>
    <name>A0A2G4EYI2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF655 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54538">
        <property type="protein sequence ID" value="PHX54538"/>
        <property type="gene ID" value="CP500_015570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="140"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="395"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="561" mass="62218" checksum="26A40DB24BE56EBF" modified="2018-01-31" version="1">MTPLYYILRRLCWLLLLTIGLAFCGQQEEEQPQLPPSLIPLPQDPLLQVYFNQSLTSSYTEPYRQQTRAGDDLEKLVMEAIATAGSTVDVAVQEFRLPGVARVLSDRQRSGIKVRLIVEHMYSRPWSDYKAPELAKLTDRDRDRYHEFVQLADTNKDGKLSAEEIQKNDALLMIKNAGIPVIDDTADGSKSSDLMHHKFVVIDGKTVIATSANFTTSDVHGDFKTPASRGNANNLLKIENAQLAQLFTQEFNIMWGDGPGGKPDSKFGVKKPFRPMQKVRVGDTTVTVQFSPTSKTLPWEKSVNSLINQNLGSAKKSVDLALFVFSSQRLANTLEIEAQRGVAVRALIDSNFIYRPYSEALDMMGATLIEHCQLEADNRPWKQPLTTVGVPALPMGDRLHHKFGVVDANTVITGSHNWSEAANHGNDETLLAIASPVVAAHFEREFDRLYKGAILGIPPRIKQKIDASKKECESVPPASKSPILMGKIVATKPQIAEAKKLVNLNTASQAELETLPGVGPKLAERIMAARKQQPFTSLDDVARVQGIGDKILEKWRDRVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYJ1</accession>
    <name>A0A2G4EYJ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000094">
        <property type="protein sequence ID" value="PHX54530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54530">
        <property type="protein sequence ID" value="PHX54530"/>
        <property type="gene ID" value="CP500_015660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="220" mass="22473" checksum="71F17B2098DD9A6D" modified="2018-01-31" version="1">MLLGNIGSDLLFGDESDDTISGGKSNDSLFGGKGNDFIHGDQDDDLIYGGDGSDVLCGDDGNDTIYGDRADDKGVSVGSTEQQDCINGGAGNDLIYGNEGEDELNGEAGNDTLYGGKDNDILFGGEGDDILFGGSGDNTLSGGVGSDQFILGANGLNTILNFEVGIDKLVLTGGLTFQQLQFTSTQNGTLLRVVGTGQVLANLVGGIGAIGPNDVRSNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYJ6</accession>
    <name>A0A2G4EYJ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_015320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000090">
        <property type="protein sequence ID" value="PHX54581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54581">
        <property type="protein sequence ID" value="PHX54581"/>
        <property type="gene ID" value="CP500_015320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="6"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="4">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="199" mass="22067" checksum="8443C58A61C47A1A" modified="2018-01-31" version="1">MSSECLRVGQPAPDFAATAVVDQEFKTVKLSDYKGKKYVVLFFYPLDFTFVCPTEITAFSDRFEDFNKIDTEILGVSVDSEFSHLAWIQSDRKSGGVGDLNYPLVADIKKTISADYNVLDPEAGIALRGLFIIDKEGIIQHSTINNLAFGRNVDETLRTLQAIQHVQSHPDEVCPAGWQPGDKTMTPDPVKSKVFFAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYP6</accession>
    <name>A0A2G4EYP6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dynamin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_014925</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54649">
        <property type="protein sequence ID" value="PHX54649"/>
        <property type="gene ID" value="CP500_014925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007791">
        <property type="entry name" value="DjlA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027094">
        <property type="entry name" value="Mitofusin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465">
        <property type="entry name" value="PTHR10465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05099">
        <property type="entry name" value="TerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="741"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="TerB" evidence="6">
        <location>
            <begin position="37"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Dynamin_N" evidence="5">
        <location>
            <begin position="267"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="865" mass="96335" checksum="1566B24BD3BC0489" modified="2018-01-31" version="1">MDTSLISSQTVELVSLLTGQRLRQEDITPPVLFLAGLVTVLLGVIHADGTVDAEEIQHLRTTLTELIPANNSLRQLVMLMVKSVREQQVYKKLTVLLALTACFSEEEKLLLISFGYQMSAADGTIDKREKQYLTLIADRLGVDARYLTVLEASFSSQTISDTAALAEVHSLLDPARFQSLDSMFVRAASHIIEHLRAKPKQQKNRKHSVSSYQELKKFQEYWQQLDAVCGKLGLTLRDGSDRNVLSPNLTEEVTKISQRLKSQCFRVAVVGEFSKGKSTLLNALLGEEIQPVRDIPCSGTVTVLKYGPQQRVICKYKDGREEEISPQKYKEKASISEEAALGSFGDEIVNSEIEEIIFEHPNLELCTNGVEIIDTPGLNEHAERTLVTEQVLKTTDAVIFLTNAQNALTKTERELLLYLKKKLNPGKDDEAAKNIFVLVNFADLLRREGSRQQVKVKVENFVKQPNLIAGENRIHLISAQSALDATLDGTENEYVKSFQDFTKSLEQFLTVERGAIALQQSAAGIKQIINTGCAELTQERKILEGKLTVSPGDKLKIFELMAEASGRDVKVKLLADELMEKCVEEAIESWNEWLEGLAERLIAKSALWTSEHSHMWSQKELTKDYSDQFVEDITQEIEDWTTQKVQSILQQNMGALNSQIDEEIYAIRQEFQKFDKQLSSNLVSQFNNLAMAGNLGEIGTSGSGIAESIDDIGDGGFMGGLGIGAVAAAVLIALPLGIIPVILGTIVAGLGGGLGLSFLDGDTVKGQIKEKVCELGFKNFDESSQSILDKIQERIIALFEKRIETSNNVMSKAISVWDNLLEQQEKRDRQNQKECEAQKVWLADKRRELEQVQNQIEAILNQSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYS4</accession>
    <name>A0A2G4EYS4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2281 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54640">
        <property type="protein sequence ID" value="PHX54640"/>
        <property type="gene ID" value="CP500_015065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="7783" checksum="5ECCEF9AFD6DE372" modified="2018-01-31" version="1">MSAKELLIQEMENIPEFILEEVWDFLLFLKIKYQKDQLENSILSESSLQQDWLRAEEDEAWQHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYU1</accession>
    <name>A0A2G4EYU1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54660">
        <property type="protein sequence ID" value="PHX54660"/>
        <property type="gene ID" value="CP500_014920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="428" mass="47433" checksum="90BEAFB1CA9E7DA9" modified="2018-01-31" version="1">MNFVFPPAVQAAIEAGKYTQVFTSAGVPIGIARDAATGQFAAHAVGAALNNSPLSPLVSPVQLAMGGLQMYQNHMGFQAVQNSLGVLQATTAVIGVGVAAGVALSAVNLHQTLKLKKAVERLEVKVENGFINLEQLVKGQGAQIKQLIAEVVADLKFENHRLVLVRAYGLFNQAIQRMRSALQLKDINRRNAEIDAARGMLFEALADYRNPQLLSETCAAGQLRRLECSWTIEQSIIATYQVQNEFGAAGDRISQLQQQIRQDGLGIIQCCDSDDELDFLFPEITRIHNHDLVVLETWQNQIDWMKALPPSELKQLQSADLSKSDSTVKVEKNSAATALAIPDEQLFYENLRPKSHFYALRTQLELMLDREQRPEYEDYIIDQGEIAGHKSLVSSNLEKASDLAVANLFWYFRVRDESEEELELANTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYV9</accession>
    <name>A0A2G4EYV9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54699">
        <property type="protein sequence ID" value="PHX54699"/>
        <property type="gene ID" value="CP500_014665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="185" mass="21188" checksum="B6ED228C82BD3111" modified="2018-01-31" version="1">MSVQTQKWLFTVQEYHLMSDAGVFANERVELIEGEIIQMAAIGKRHAARVDRLARLFSHISESLVIFRVQNPICLNDKSEPQPDIALVQPRADFYEESLPNTEDILLLVEVADSTVNYDRDVKVPNYARSGIREVWLWDLEVNCLEVYRNPTANGYTLMQKFERGEVVSPLAFPDFEVSVDLILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYW1</accession>
    <name>A0A2G4EYW1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014625</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000082">
        <property type="protein sequence ID" value="PHX54715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54715">
        <property type="protein sequence ID" value="PHX54715"/>
        <property type="gene ID" value="CP500_014625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="152" mass="16808" checksum="F845A9F445FCC6D5" modified="2018-01-31" version="1">MTVKIGDTAPDFTLTSQTGSSVSLKDFRGQKNVIVYFYPKDDTPGCTAEACAFRDSYEVFKDAGAEVIGISDDSQQSHQKFATKYQLPFTLLSDGGNKVRQLYGVPATLWIMPGRVTYVIDKQGVVKHIFDSMLDFKAHVAEALKTLESIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYX4</accession>
    <name>A0A2G4EYX4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">P-II family nitrogen regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000104">
        <property type="protein sequence ID" value="PHX54387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54387">
        <property type="protein sequence ID" value="PHX54387"/>
        <property type="gene ID" value="CP500_016385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="133" mass="14186" checksum="A7D48A648770704A" modified="2018-01-31" version="1">MQLVIAIIQPGKLDSVKEALVKLGIQGMTVTGAKGFGRQKGRPLAFLGLLDMEGKPFTVDFLPKVRIEIVVNDDIVDAVVDTIVAAAKTGTVGDGKLFVIPVSRAIRIRTGEENEAALTIEEPATLSDSRKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYY7</accession>
    <name>A0A2G4EYY7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000082">
        <property type="protein sequence ID" value="PHX54710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54710">
        <property type="protein sequence ID" value="PHX54710"/>
        <property type="gene ID" value="CP500_014600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="12"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="189" mass="21369" checksum="3634935AB3F29543" modified="2018-01-31" version="1">MTLLDLRLLTVQEYHLMAEIGILDEDERVELLAGQIVKMAAKGTAHGAGVKRTVELLENRLGRLVLVSVQDPVRLNDNSEPEPDIALLVRDPLYYEDHHPTPSEIYLIIEVADTTLRTDLGIKANLYAESGIADYWVLDVNNRQLHVFREPSQDGYQSIAVLGDDASISPLQFPNIYFDVRDMLRPLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ38</accession>
    <name>A0A2G4EZ38_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54771">
        <property type="protein sequence ID" value="PHX54771"/>
        <property type="gene ID" value="CP500_014405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="124" mass="13523" checksum="BAC870745BBBE602" modified="2018-01-31" version="1">MAKILLVEDNEMNRDMLSRRLARKGHEVFIAVDGAEGVSMAIAKIPDLILMDMSLPVLDGWQATEQIKAAPETSTIPVIALTAHAMAGDREKCLAAGCDDYDTKPVEFPRLLSKIELLLKGAMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ46</accession>
    <name>A0A2G4EZ46_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54795">
        <property type="protein sequence ID" value="PHX54795"/>
        <property type="gene ID" value="CP500_014095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="SSF56726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="446" mass="50460" checksum="EB72EF07B27FCC0D" modified="2018-01-31" version="1">MGMKCVQCNTDNDLSDRTTNSGRCKQCNHPFVFEPTTVTDENLQFTDPFFKKAIDDISSQNMLFFTPKQFLYFIDKRLKKSRPLPIFLFISIYLFLGILYMGLFVDQLSGLPLLKDLPLQFLILIVFIVYNVFWIWVFFQSSKSPQLGIRSRRESAKELQTLGMIILVTGIPLSIIADYFPGYIAASLLGLYSYWLGISQKNRQHEIPEIFLVNQAQSDEWLQRWQTVNGTVEKLLPAPRQNALPASIDPEVSAYSFDRAIICDSDEIAQFLIANNVHFENNCAILSINGYPQSIFDTVIQMLRRNADLKVYALHDANPAGVSLVHQLRTSPNWFADQVVTIFDLGISPRQILETRDMFVQQSQTMAQSARQLPNAVRQGLTAQELAWLDAGNFVELESFTPQRLLRVVNYGLAQSGDPQGNEGLILVDDNVGYGGGYVFVSDSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ64</accession>
    <name>A0A2G4EZ64_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54477">
        <property type="protein sequence ID" value="PHX54477"/>
        <property type="gene ID" value="CP500_015950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7851" checksum="8FF69DCD03795966" modified="2018-01-31" version="1">MGHREFFPALQKPGFLKKPGFLISCTCYIFLGWAGRMPTPQQKLIFVEQASCLLLKMAQDIQFSEISVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ86</accession>
    <name>A0A2G4EZ86_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NnrU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54816">
        <property type="protein sequence ID" value="PHX54816"/>
        <property type="gene ID" value="CP500_014125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009915">
        <property type="entry name" value="NnrU_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07298">
        <property type="entry name" value="NnrU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="NnrU" evidence="2">
        <location>
            <begin position="13"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="237" mass="26691" checksum="ECA8C8AF79CFF36C" modified="2018-01-31" version="1">MTIDLALNSHLVILGLLLGFAIAHSGLAALRPQAEKLIGARLYRVLFALVSLPLAVILVIYFFNHRYDGVQLWQVQGVPAVKPLVWILSAISFLFLYPATFNLLEIAAVQKPQVHLYEAGIIRITRHPQMVGQVIWCIAHTLWIGTSFTLVTSIGLVLHHLFGVWHGDKRLQARFGESFETIKSRTSIVPFLAILQKRQTLDLLEFLRPSYLGIAIFIGVLWKIHPLLMRATGSIDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZE0</accession>
    <name>A0A2G4EZE0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_013835</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54858">
        <property type="protein sequence ID" value="PHX54858"/>
        <property type="gene ID" value="CP500_013835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009736">
        <property type="term" value="P:cytokinin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006189">
        <property type="entry name" value="CHASE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042240">
        <property type="entry name" value="CHASE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03924">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0932">Cytokinin signaling pathway</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="372"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="333"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="647" mass="72743" checksum="A1DCCFBC0DA18D0A" modified="2018-01-31" version="1">MRVNKLFNLATSTLLDYRRYIQVGLTLCAGLGLSAIACSIAYNWEYKFMQAELQERLDKIATDIQRDVGGNIEVIRAASAFYSVFEDDKKPEIKQFVGSALYRHPSLKAIAWLPRVSESQQFLTDEIDLGLDLTPNRRALEQAAKRQEITATERQILPTQNLSSIFVFQPIFSKVSAGNTSGLASSVPVLKQENLKGFTLGVLLIDAVVKSAVQETKLNFVNVDIQDAMASESERFLAFYESKTKRIITDENTKNQLQIGERIYCPDGSSCTRILNIENRRWLLRFLVTPEYINPLKYWRSLTVLVFGTVLTLAATSYLLSLLNYTDRIEKVAAERTAKSQELAKTIQELQETQSQLVQQEKMSGLGLLVAGVAHEINNPINFIYGNIHHASEYARDLLELVELYQKHYLYPPSEISEHLENIDFDFLCQDMRQLLSSMKIGADRIIQLVQSLRNFSRLDESEMKPVNIHEGIDSTLLILQSRLKATDSRPPIGVVKNYGNLPMVECYVGQLNQVFMNILANAIDALDSYSIERGEWESKINPSTIAIATEYSMPDKITVRISDNGHGIPENVKQRLFDPFFTTKPAGKGTGLGLSIGYKIVVEKHKGTLRCDSTPGLGTEFSIEIPLRQEVRKTAPLVSHKTSEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZJ1</accession>
    <name>A0A2G4EZJ1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA interferase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Toxic component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PemK/MazF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54929">
        <property type="protein sequence ID" value="PHX54929"/>
        <property type="gene ID" value="CP500_013500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR033490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="13167" checksum="744B2ABDA6E3254F" modified="2018-01-31" version="1">MNSLRRGQIIDVDLEPTRGSETGKVRPCIIVTNDVYNARVPVIQVVPITEWNEKKARISTNIDLDPSAMNGLAKRSIADCLQTRPIDHRQRLVRVRGELSGEDLARVDGAIKQVFGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZM4</accession>
    <name>A0A2G4EZM4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000086">
        <property type="protein sequence ID" value="PHX54647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54647">
        <property type="protein sequence ID" value="PHX54647"/>
        <property type="gene ID" value="CP500_014910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="13210" checksum="C5D05726C19002A0" modified="2018-01-31" version="1">MQLILAEFCGCWGCSWWENIITIILVSLKGKGAVLLLGLLLIPIVLVVLILLLCLMPAFEFIASFGRDKQDIKNLNNSQEQDPTILSAGAKFVGRKAAKYLGRKLRERNKHEDVNNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZV4</accession>
    <name>A0A2G4EZV4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protease 4</fullName>
            <ecNumber evidence="3">3.4.21.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Endopeptidase IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protease IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Signal peptide peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sppA</name>
        <name evidence="7" type="ORF">CP500_012810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55042">
        <property type="protein sequence ID" value="PHX55042"/>
        <property type="gene ID" value="CP500_012810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004634">
        <property type="entry name" value="Pept_S49_pIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004635">
        <property type="entry name" value="Pept_S49_SppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001217">
        <property type="entry name" value="Protease_4_SppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00705">
        <property type="entry name" value="SppA_67K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00706">
        <property type="entry name" value="SppA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="6">
        <location>
            <begin position="134"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="6">
        <location>
            <begin position="385"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001217-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="606" mass="65951" checksum="12ECD5C734E16CAA" modified="2018-01-31" version="1">MKDFLKYTFASLLGSLLGLVLIGSIGLGGLVILIAMAASSSKDSGPQVKDKSVLVLDLSLNITDSKPSRSTGAAIEEVLSDEGADTVTLRSVLDAIASAEKDPKIVGIYLEGNSDSGGSGFANLKEVRSALQRFRDTKKPIFAYEMDWNEREYYLGSVANTIAMNPFGSVEINGFSSQTMFLAGALEKYGVGVQVTRVGKYKSAVEPFLLKKMSPENRQQTQKLLGDIWGQYLTTIGPNRKLTVPQLQAIADNGGTLMAEEALKSKLVDKVVYFDEIVTELKKLTGTDAEDKSFKQISLKNYARIAENKNSNRGDKNKQVAVLYAEGEIVDGEGGVSQVGGDRIAEELRKIREDDDVKAVVLRVNSPGGSVTASEVIGREVVLTAKKKPVIVSMGNLAASGGYWISMGSRKIFAESNTITGSIGVFGILPNVEKLAANNGLTWDVVKTTRFADINTISRAKTPQELANIQKVVDRIYDRFITKVADSRKLPKDQVLEIAQGRVWSGAAAKELGLVDEIGGLQDAVKEAAKQAKLGNDWQLEEYPKRRSLEERLLEKLSGVRASKAAVKLDPLTAEVKKMQEELAVVKSMNDPQGVYVRMPFNWRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZW6</accession>
    <name>A0A2G4EZW6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate/guanylate cyclase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55060">
        <property type="protein sequence ID" value="PHX55060"/>
        <property type="gene ID" value="CP500_012920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="454"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="612"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1058" mass="119615" checksum="ABFD1F19010C76A5" modified="2018-01-31" version="1">MTSASFNQSAPGNAIIDVTPVSEHHQEQHSHYPSSSSQIVTTQGNGNFSNFLAPLNKDSFKGVAKDVEEKLRVVNQTLGMLDNLLDSQGFDAILNEMLQSITQKTGELLNAARSTIFLLDDEKNELWAIVAKDENGKNLELRFPSNVGIAGEVATDRTVVNIPYDFYNDRRSTNAKKTDERTGYRTYTMLAMPLINEDTQELVAVVQLINKLKPNHENYAHLDEQIDREGFTREDEQIFREFAPSIRLILESSKSFYAATQRQRAATALMNAVNALSQSSLDLEDTLKRVMDQAQELMNADRSTLWLIDEDRDQLWTKIPSKDGVLEELRIPSNAGFAGTVAQSGKPLLIPFDLYEDSRSDTSKKTDQQFGYRTCSMLCMPVFNADKKLIGVTQLVNKKKQGKFPPYNPEDWPHAPEQWRASFNHSDMEFMKAFNIQAGVALQNAKLFAEVKQQEQRQKDMLHALTNGVISTDQKGNIVATNPSAKKLLGVSDARLAEGQSLRELINLERGDFAKWFDVALSPTEDKDRQQYYPDQVLIALEGKQQSINLSLNSMTDATDPSKVNGALVVMEDISSAKQVKNLMYRYMTPEVAEALLASGDTGMGGTRKNVSVLFSDIRGYTTLTEKLQAEEVVEMLNQYFEKMVDVVFKYGGTLDKYIGDALMAVFGSPAPLADHAWCAMQTAVEMREQLIKFNKQRVDNGELEISIGMGIHSDEVVSGNIGSSRRMELTSIGDGVNLASRLEGASKQYGTDLIISDNTYKQYKERLYVRELDFITVKGKSEPVIVYELVGIREGCSPIGKPLTEKQQKIVDHYNKGREHYKTPVTQKLSEDEVKKILADVAKMPETEIKKLSYNVDEQLERELKKLLYQLKKQSEYDLTNLSEADKMFQSEIQLLKLEGMKNLSEDEATLLLKSKVRNLSADDIKDLQEGEVKKILEADINQPSKLKIKRLKSSDIRQLLQAKIKTRVTETVIEILDEEFENLGLDRVKKLLSEFKKYLEPKAYKSFKEAEQEFKAVQEADPKNKAAKLHVDRCMLFQHRFSDVLNWDGVWNLTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZW7</accession>
    <name>A0A2G4EZW7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Diheme cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55056">
        <property type="protein sequence ID" value="PHX55056"/>
        <property type="gene ID" value="CP500_012900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018588">
        <property type="entry name" value="Dihaem_cytochrome-c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09626">
        <property type="entry name" value="DHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="187" mass="21441" checksum="BB072668F313A108" modified="2018-01-31" version="1">MKQATPRKRRRVSWRGIYSTLLLLILVCCTGGWFATQTAYSSPPARLAQVSAIEDTATVDRIPDRYQLGQQLYLENCATCHIGLPPQVLPTETWRRLLQDSQHYGQTIKLLVDPPRLLVWNYLQTFSRPQTKEEELAYRVASSRYFKALHPKVKMSQPANISSCVTCHPGVSQYNFRKLSAEWENSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZX7</accession>
    <name>A0A2G4EZX7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55055">
        <property type="protein sequence ID" value="PHX55055"/>
        <property type="gene ID" value="CP500_012880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="7959" checksum="453C59C44DA41D42" modified="2018-01-31" version="1">MPSENQDLPKTETPQGHNCLIPSDFVLSLLALPLLGGLLAAKATAEFVSSIGIESEEVFRGSRLPVLNFPHSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F009</accession>
    <name>A0A2G4F009_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="3">DERA</shortName>
            <ecNumber evidence="3">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="3">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">deoC</name>
        <name evidence="4" type="ORF">CP500_012530</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55094">
        <property type="protein sequence ID" value="PHX55094"/>
        <property type="gene ID" value="CP500_012530"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="3">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="225" mass="24416" checksum="10E55452A3B4234C" modified="2018-01-31" version="1">MRSNQPDIDIAPLIDYGLIDPTATPEQVEHFCQQADRFGFVTVCVYPSYVRQAVELLHDKRPKVCTVIGFPTGASTSTVKLYEALEAADNGAVELDVSVNLGLLKAGRIDEFHRELAQICEETNLTIKAIIESSLLSDAEKQLAAEICMEAGVAYIKTNTGFFGAATVDDVRLLKEVTKGRIGIKAAGGIRTHEQALDLVVAGATRLGTSRGPELLRQRDNLDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0A1</accession>
    <name>A0A2G4F0A1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55194">
        <property type="protein sequence ID" value="PHX55194"/>
        <property type="gene ID" value="CP500_012095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="264" mass="29735" checksum="F8C8977D297FE4E4" modified="2018-01-31" version="1">MIRNMKRYLHIVKLFWGAAISAELEYRINFLLAALSSLGNLTGSLFGLFLFYRKGYTFSGWKWEEALVVLGIFTILQGFSSTFLAPNLSRIVDRVQQGTLDFVLLKPINSQFWLSANTVSPWGVPDIIFGAVLMLYSANKLGVEISNYFLTAIPLLFGMVSLYSIWFMLGATSIWFVKIYNVTEVLRGLLEAGRFPMAAYPTAYRFFFTFIVPVAFLTTVPAEVMLGRGDIVWIGGAGILAIALLFASRYFWQFALRFYTSASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0F4</accession>
    <name>A0A2G4F0F4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55244">
        <property type="protein sequence ID" value="PHX55244"/>
        <property type="gene ID" value="CP500_011725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="6823" checksum="B321B2CB7B34B74F" modified="2018-01-31" version="1">MPALPVHDFVSVSGIGATTGGLPLQENETALGARGDLDLIVKQQSVTRFELKLTLXHGGTAPTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0L9</accession>
    <name>A0A2G4F0L9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recN</name>
        <name evidence="7" type="ORF">CP500_011695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombinational repair of damaged DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RecN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55300">
        <property type="protein sequence ID" value="PHX55300"/>
        <property type="gene ID" value="CP500_011695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003128">
        <property type="entry name" value="RecN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00634">
        <property type="entry name" value="recN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="6">
        <location>
            <begin position="2"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR003128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="584" mass="64384" checksum="B4074F9D5C15EDA5" modified="2018-01-31" version="1">MLLSLRIENFALIDCLDLEFGPSLNVFTGETGAGKSIILDALDVVLGGKVDRRVIRTGAARAILEATFELDKAAVLWLGEQEIEPIDGNLAVCSREITASSGTLRTRSRLNGILVNRPLMEQLRDRLVEITAQGQTVQLGQETLQREWLDLYGGKTITEARSNVTAAWLVTSQAKTALNRRRQSEQQRLQRLDLLEYQVRELSEAHIEDAAELENLEQESIRLSHVVELQQQSYQVHQALYQNDADSPSAADLLSKAEAILNDMAVYDVQLQPILEMVSDALAQATEASRQISSYGEQLEADPQRLEEVEERIQELKQICRKYGPLKEAIAYYKTIQNELNELLAGGESMEALELAYQASMEKLKEACSHLTNLRRATALKLEADLVAELKPLAMEKVQFQVEITAATPSTTGADRISFCFSPNPGEPLQPLGAIASGGEMSRFLLAIKACFSQIEGASTLVFDEIDAGVSGRVAGAIAKKLHQLSEKHQLLCVTHQPLIAAMADCHFRVNKQTIASEAGTNKDTSNPESSERTVVRVMTLNSQQRREELAQLASGRSETEAIAFAESLLTQAASLRQIQSKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0P1</accession>
    <name>A0A2G4F0P1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55321">
        <property type="protein sequence ID" value="PHX55321"/>
        <property type="gene ID" value="CP500_011495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="681" mass="76455" checksum="EEA45D54D2D8972B" modified="2018-01-31" version="1">MSLVDLANTKIRVIGCSAVMAVGQIISSAIANPGTQAAAGMIGGPIALGGVSILAAIACSMAETMAADELANRMTERLRKNAKILDNHDLIKAAGEAIGYILREVAKSDQLIAIARSQNLPSPERALDRLAQKTPQYWLDINTSTADLSRGLQISEDQLTKIFSADVEEFDRVTGLTPADWANFVNEFAASDRKSFDAEIVEFVSNKLYTTFPKAYREVLKLDAAKGGEKFAAMLLNLHQIALAELRNLGLQNGEILQKLEAVATQQQICQVMVKLEAIEIGIRDDLAQIQNLLERFVDISAPRLPLPYECETIIADRTQDFTGRRFVFAAIAEFLQNNRKGYFVLEADPGVGKSSIMAKLVLLLKRRCVAHFNSQSQGIVRADQFLENACTQLIRRYQLNYPQLPENATRDGNFLSRLLGEVSAKLGWKKLIIVVDALDEVDSSLQGRGSNVLYLPDALPDNVYFIVSKQPKTLPLPNHQVFDLMQYSAESLADVKVYIDKRTSNSASIQSWINRQNLQREQFVAAVAEKSQNNFMYLRYVLNDIDSGKYSDVNLQDLPRELEGYYDKHWARMEMAIKDKELRRRKLKVIYLLTKVRKPVSCDILADFAEEDALDVQEVLDDWEQFLRRSGDSPPDYSIYHASFQRFLHRIDVVQKAGVSLRDIETAISDNLWEDLYGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0W7</accession>
    <name>A0A2G4F0W7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_010810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000053">
        <property type="protein sequence ID" value="PHX55424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55424">
        <property type="protein sequence ID" value="PHX55424"/>
        <property type="gene ID" value="CP500_010810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013646581" evidence="4">
        <location>
            <begin position="25"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="520"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="554"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="659"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="693"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="727"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="761"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="795"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="829"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="902"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="936"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="970"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="1004"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="601"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1054" mass="118006" checksum="63DB3CF5010A6CD8" modified="2018-01-31" version="1">MKNRPLFILACLSSFLLISPILSGCDRVNTFVQQFQPAGLRELKEADLKEFAESITVRVTTNKSKSGGSGTLIRKDGSRYTLLTNAHVLGNDEAPYRIETPDKKTYSASVVESVKFSDNDLVLLEFVSDSNYATANFPDLTNINASKYVNLGEKVYATGFPFDEENLNFTTGTVGLFPQKTFKTGYRIGYTNAIKKGMSGGPILNRFGELIGLNGRHSYPLFGDPFVFQDGTRPSETEREKMLPLSWGVPVEILAQTASQFLNPPSQTLTGLPSDIATKAKQIAVRIERKVGGGSGVIIASHKENGNKYTYHVLTAAHVVETEQDYTIITPDNKRYTIKPGTEKKSKSSDIAVLSFTSDVNYSVATLGNYELKDKSYSFVFGWPISNNYTKPISLLTSGSISSPQTTQLYHAKDVFSLQNGYELAYSNMTQGGMSGGPVFDTQGRVIGIHGQIEAEDGVNIGYSLGIPSKKILGLIDNFGIQKEWLRVETSAPPLPEKEEVDNILQMSLTIAKPSNQAKEEDWISYGNQLWRFRKYSDAIDAFDKALAINPKSSLAWYARGLAVLAQDNYVDAVRCFSKAVEIKPDFYAAWRKKGDAHDSLKQYGFALDAIERAIEEAEKQNQKDFALYWRKGVTLNNLKRDPEAIIAYTKSIEIQPHPYPYNNRGSVYSDKGDKDNAFKDFNEAIKLDPKFAYAYNNRGSLYSDKGDYDNALKDYNEAIKLDPKNAKAYNNRGNLYADKGDYDNALKDLNEAIKLDPKLAAAYDNRGSLYSDKGDNENAFKDYNEAIKLDPKYANAYGNRAFVYYDKGDYDNALKDFNEAIKLDPKYARAYNGRGLVYEKMGNQEKAIAEFKTAILYCGTGALNCQVPQRNLNRIQNKSKGDNDNTLKDLNEAIKLDPKDAKAYYNRGFVYYKKGDNDNALKDYNEAIKLDPKYAIAYNNRGLVYLGKGDYDNALKDFNEAIKLDPKFAQAYVNRGAVYSDKGDNDNALKDFNEAIKLDPKYALAYDTRGLVYEKMGNQEKAIADFQKALLYCGTETLICEYPQNHLNRLQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1F1</accession>
    <name>A0A2G4F1F1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system HicB family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55590">
        <property type="protein sequence ID" value="PHX55590"/>
        <property type="gene ID" value="CP500_009950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031807">
        <property type="entry name" value="HicB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15919">
        <property type="entry name" value="HicB_lk_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HicB-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8590" checksum="838577ADCC7EC8C9" modified="2018-01-31" version="1">MKLPYIIVIQWSDEDKCYLVHLPDFPSQQFHTHGNTYEEALQNAVEVLELLVEEYQTDGKSLPAPKTLVGNLLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1G9</accession>
    <name>A0A2G4F1G9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Ycf48-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_009980</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Unknown. The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the Ycf48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55596">
        <property type="protein sequence ID" value="PHX55596"/>
        <property type="gene ID" value="CP500_009980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01348">
        <property type="entry name" value="Ycf48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028203">
        <property type="entry name" value="PSII_CF48-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016705">
        <property type="entry name" value="Ycf48/Hcf136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14870">
        <property type="entry name" value="PSII_BNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017875">
        <property type="entry name" value="PSII_HCF136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PSII_BNR" evidence="4">
        <location>
            <begin position="33"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="BNR 1" evidence="2">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="repeat" description="BNR 2" evidence="2">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="BNR 3" evidence="2">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="BNR 4" evidence="2">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR017875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="337" mass="36767" checksum="25D347766E57F2D1" modified="2018-01-31" version="1">MVCSKTIVRFWQRIVMLLAAALICAGCSTIGSVSYNPWQVIALPTQANLQDIAFAGNDQHGWVVGSEATLFETTDGGTNWKPIALDIDDTRSRFSSVSFSGSEGWIVGQPSVLLHTDDEGKSWTRIALSSQLPGSPSTIAAQGPNSAEMTTDVGAIYRTSDGGKNWKAVVQDSFGVVRNINRSEDGQYVAVSSKGNFYSVWKPGQNTWEPHNRNSSRRLQNMGFTKDGRLWMIARGGQIQFSDASEAEGWGKPFFPDRKASWGLLDMAYRTNDEVWVAGGGGNLLCSLDGGKTWQKDREVEDVPANFYRIVFMGPERGFIIGANGTLLKYQGSAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1I1</accession>
    <name>A0A2G4F1I1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55605">
        <property type="protein sequence ID" value="PHX55605"/>
        <property type="gene ID" value="CP500_010025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="17330" checksum="848D7ED55A9F85E6" modified="2018-01-31" version="1">MTPTLFGRWQTRIFLLATVGVLFTLPFAFGYVGNEASTIYFWVLFYVGLLGLGWDILYDWLQKFLWDHDWPGIFQFFAAIAESVLLVLLIKTDLLPFISSSEFHLEWFTLHYSLVSFAAYVSSWVVMRLLFPRWRFRGGVWIGKWPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1I6</accession>
    <name>A0A2G4F1I6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14">Cytochrome b559 subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">PSII reaction center subunit VI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">psbF</name>
        <name evidence="16" type="ORF">CP500_009990</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="13">With its partner (PsbE) binds heme. PSII binds additional chlorophylls, carotenoids and specific lipids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 13">Heterodimer of an alpha subunit and a beta subunit. Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13 14">Cellular thylakoid membrane</location>
            <topology evidence="13 14">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13 14">Belongs to the PsbE/PsbF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55598">
        <property type="protein sequence ID" value="PHX55598"/>
        <property type="gene ID" value="CP500_009990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00643">
        <property type="entry name" value="PSII_PsbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006241">
        <property type="entry name" value="PSII_cyt_b559_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006216">
        <property type="entry name" value="PSII_cyt_b559_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013081">
        <property type="entry name" value="PSII_cyt_b559_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33391:SF14">
        <property type="entry name" value="PTHR33391:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00283">
        <property type="entry name" value="Cytochrom_B559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000037">
        <property type="entry name" value="PsbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01333">
        <property type="entry name" value="cyt_b559_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00537">
        <property type="entry name" value="CYTOCHROME_B559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13 14" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="6 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_B559" evidence="15">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared with alpha subunit</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX55598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="45" mass="5107" checksum="10687E3BFE252AAA" modified="2018-01-31" version="1">MTSRTPNNEPISYPIFTVRWLAVHTLGVPTLFFLGAIAAMQFIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1M8</accession>
    <name>A0A2G4F1M8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55377">
        <property type="protein sequence ID" value="PHX55377"/>
        <property type="gene ID" value="CP500_010900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="9289" checksum="BD5459E8175C8EB5" modified="2018-01-31" version="1">MTVMRELIQQELEKLDREQLQQVFEFISFLKFRARLVTIPAIDETNLAALYSEFAEEDRQLAELGISEYAELLKHEDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1R2</accession>
    <name>A0A2G4F1R2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase C26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55685">
        <property type="protein sequence ID" value="PHX55685"/>
        <property type="gene ID" value="CP500_009295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044668">
        <property type="entry name" value="PuuD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43235">
        <property type="entry name" value="PTHR43235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="248" mass="26732" checksum="3A312FB378C467D7" modified="2018-01-31" version="1">MKKFPIIGITTYNRCPAGEYRLNGSYIDAVQAAGGIPILLPPNQLNPASIFDAVDGLIFSGGGDINPELYGGLIDRTVYAIDAERDSFELGLAKLALKANIPVLGICRGMQILNVASGGSLVTHVPDAYGDEVSHGAGIPPRAIEHTIEIEPNSRLGKIMGTTSTTVVSWHHQAVRKVTSNWKIVADAPDTLVEAMEHQNHPWMIAVQWHPEMSPKCAVNSQIFRAFVQAAAAKLVSYREIGLKTPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1U0</accession>
    <name>A0A2G4F1U0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55734">
        <property type="protein sequence ID" value="PHX55734"/>
        <property type="gene ID" value="CP500_009240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="9730" checksum="0802F96490D9B860" modified="2018-01-31" version="1">MRLSKQHGWVIGEAIIGTVVGAINSSAGLVLTFGLVCFHICFDKHPEEDSRCPLERVLNSEEVVKLASCKDCPFKKGAVDVEKVEEEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1V7</accession>
    <name>A0A2G4F1V7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55732">
        <property type="protein sequence ID" value="PHX55732"/>
        <property type="gene ID" value="CP500_009230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="142" mass="16066" checksum="DB6E8844FCBC57AE" modified="2018-01-31" version="1">MKQVLPLLTGIAIASISIAAFIPPSYVLRLETVKQGTLRLTNTSNQRIYVKNFVLRNHKVNEFGKRIGEDEDMSIRVESSLNPGESRLETTSDAPRRTTANTELLRWNDGKKNHRQGLLICFINDFNHNVYLTPNGQLSCPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1W9</accession>
    <name>A0A2G4F1W9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HEPN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55735">
        <property type="protein sequence ID" value="PHX55735"/>
        <property type="gene ID" value="CP500_009250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007842">
        <property type="entry name" value="HEPN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05168">
        <property type="entry name" value="HEPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN" evidence="1">
        <location>
            <begin position="8"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="14234" checksum="F10B5E0367581712" modified="2018-01-31" version="1">MIPEQIALLTKAGESLRAARLLVANALPDFAASRAYYTMFYVAEAFLLGEGLSFSSHAAVISAFGREFARTGRVPVEFHRYLISAQNQRNQGDYDIDPAIPEDEANQLIAQAEQFLDLAERLLGNQPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F238</accession>
    <name>A0A2G4F238_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LytR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_008950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55805">
        <property type="protein sequence ID" value="PHX55805"/>
        <property type="gene ID" value="CP500_008950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="3">
        <location>
            <begin position="109"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="346" mass="38697" checksum="4C7D54B2E8C62418" modified="2018-01-31" version="1">MKNLSIFKRNFFKPCDRISRQKPRKTLYMLGLWLFLILGVISAAIGAITALLAPVEPQMMSQVLDATGFNQISSTTSASRMSRPVNILIMGVDRVPEATANSPKTFDGRSDTILLLRLDPRDKSINLLSIPRDTKIEFPAINFSKIGEANAKGGSNLALRLVSGLLNNITIDRYVRVNTGALRELVDLLGGIEVFVPRTMSYQDNTQKLKINLAKGWQTLNGEQAEQFARFRNDGLGDIGRMTRQQSLIQAIRNRLGSPSVVVRLPEIMRVMQKSVDTNLSFEEILTLATFGVQLEPDNFKIVMLPGRSSSAEGDLRSYWILDKAKRDRIMAQYFKQGALDFTQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F257</accession>
    <name>A0A2G4F257_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55825">
        <property type="protein sequence ID" value="PHX55825"/>
        <property type="gene ID" value="CP500_008705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013486">
        <property type="entry name" value="SpoIID/LytB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013693">
        <property type="entry name" value="SpoIID/LytB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30032:SF4">
        <property type="entry name" value="PTHR30032:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08486">
        <property type="entry name" value="SpoIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02669">
        <property type="entry name" value="SpoIID_LytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013646582" evidence="1">
        <location>
            <begin position="38"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="SpoIID" evidence="2">
        <location>
            <begin position="243"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="551" mass="61684" checksum="36E98BFF7EBDF383" modified="2018-01-31" version="1">MSFQAPQTPTYKWFSCISSTVLTALCLWPLASTAATAQSPQNREIKIGVVQRFGTKATDKLTLKAIPGDSLTLSYKTPKGIETAKVPSIKLEIAAKPLETPAVEERVVLSSHRSFESAEDSANKWRAKGIEVEIAQPLRWQVWAKRDNYNSPLVRRLLLQSLQTQGNKTAFLDTKVLKQVPQAFWVLNGFRFNRNELDVVAGKNVIEVTEQTTQEATATEPEKAIQQTRRYGGSLHLQKNAYGTYTLVNEVPTETYLRGVVPHEIGAFSPYASIVAQTILARTYALRNLRRFAIDNYELCADVNCQVYKGLTEVYPQSDKAIAQTSGLVLTYENQLVDALYSASSGGVTALFGDVWHGPERPYLRSIVDSPNNIWDLSKQSLSDENNFRRFMSLKKGFNEEKQDTFRWREEASLTSIAGFLKQYLQKKQHPLANFKTISQVLVVERSPGGRVLQMKVQTDLGAIDIDKDEIRNAFYPPISTLFYLDPIYNPDKTLNGYAFVGGGFGHGVGMSQTGSYNLANLGWSGDRILSFYFPGAQVVPLNDAITFWRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F294</accession>
    <name>A0A2G4F294_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4189 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55881">
        <property type="protein sequence ID" value="PHX55881"/>
        <property type="gene ID" value="CP500_008270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025240">
        <property type="entry name" value="DUF4189"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13827">
        <property type="entry name" value="DUF4189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4189" evidence="1">
        <location>
            <begin position="233"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="336" mass="36791" checksum="3921EF3E7C7258D5" modified="2018-01-31" version="1">MIDKYRIKAIYLEKYTHNLKRSAKLFVATLSTISLVAGCSLLDFSSGVEVKVTDIPVGQPELKSGKMMALTESKSIKQQGFEHAQFNIIYTANAIQDQIKISIDRNSVFSGRRVGKYQSGSLLDRAFTLSFTSFNKTSGNIVGEITEPGLKMYFQGKVVGTQLNFTITKSVTGIVWESTLPDNIKGTFFSLRQTSDSRVMKGRFKNDNLLKSIEGDVYLLLPSSSTTKSTEKWGAIASGSSSQDFGRSWGYSTREESEIIALESCQKRFRSCRSLVSFNNCAAYAGGEPYASANSAGAWATSTSLNAAKNRALQICQQQGICKIITAFCSDGRGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2H8</accession>
    <name>A0A2G4F2H8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Coproporphyrinogen-III oxidase</fullName>
            <ecNumber evidence="7">1.3.98.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hemN</name>
        <name evidence="11" type="ORF">CP500_007895</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>coproporphyrinogen III + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 CO2 + 2 L-methionine + protoporphyrinogen IX</text>
            <dbReference type="Rhea" id="RHEA:15425"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="1.3.98.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7 9">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (AdoMet route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the anaerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.98.3" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55960">
        <property type="protein sequence ID" value="PHX55960"/>
        <property type="gene ID" value="CP500_007895"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00323"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051989">
        <property type="term" value="F:coproporphyrinogen dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004558">
        <property type="entry name" value="Coprogen_oxidase_HemN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000167">
        <property type="entry name" value="HemN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00538">
        <property type="entry name" value="hemN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="51"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="72"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="118"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000167-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000167-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="469" mass="53627" checksum="7015FEE231E56EE0" modified="2018-01-31" version="1">MKHLSQTVEFDAALLSTYNQPLPRYTSYPPATELSTDFDRNAFQTAIAVGNHKQTPLSLYCHIPFCETPCYFCGCNTIITQRKEVAEPYLGYLARQIRQVAGLVDADRLVHQLHWGGGTPNYLDRTQVEFLWNQFNQYFRFDDAAEISIEINPSYIDREYILFLRQLGFNRISFGIQDFNPIVQEAINRVQPEAMLFDVMDWIREAGFESVNVDLIYGLPFQTEATFQETVQKTLQLNPDRIAVFNFAYVPWIKPVQKLMPESALPDAAEKLEILQNSIAQLTQNGYVFIGMDHFAKPNDELAIAQQAGQLHRNFQGYTTKPESDLLGFGMTSISMLQDVYTQNHKGLKDFYRAIDAGELPIEKGVRLNQDDLIRRTVIMELMCQFQLSVPDLEEKYHLGFDLDFNDYFAQELPKLAPLEADGLIKRWGDGIEVTAIGRLLIRNIASVFDAYLGDRMGDRGTKTFSKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F386</accession>
    <name>A0A2G4F386_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56208">
        <property type="protein sequence ID" value="PHX56208"/>
        <property type="gene ID" value="CP500_006785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="260" mass="28277" checksum="5216E9E0C7449B59" modified="2018-01-31" version="1">MISLKNQIVLITGASSGIGAACAKIFATGGAQLILAARRIDKLDRLAKELVETGLIPSANQIHLLELDVRDRLKVESALNTLPEAWKAIDILINNAGLSRGLDKLHEGNFQDWEEMIDTNVKGLLYMTRYIVPGMVNRGRGHVVNIGSIAGRQTYPKGNVYCASKAAVKVISEGLKQDLLGTPVRVTEIEPGLVETEFSNVRFHGDAEKAKNVYQGLTPLTPDDVADVVYFCATRSPHVNISEILLVPTDQASATLVHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3C5</accession>
    <name>A0A2G4F3C5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Triosephosphate isomerase</fullName>
            <shortName evidence="3">TIM</shortName>
            <shortName evidence="3">TPI</shortName>
            <ecNumber evidence="3 4">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tpiA</name>
        <name evidence="5" type="ORF">CP500_006240</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="3 4"/>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56262">
        <property type="protein sequence ID" value="PHX56262"/>
        <property type="gene ID" value="CP500_006240"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="225"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="3">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="241" mass="26691" checksum="22EFAF1EDDCE8D9C" modified="2018-01-31" version="1">MRKIVIAGNWKMYKTRAESLEFLQGFMSCLTETPEEREIVLCVPFTSLEIVSKNLHGSLVRLGAQNVHWQESGAYTGEISGPMLTELGVRYVIVGHSERRQYFGETDETVNLRLKAAQKYGLIPILCVGETKAQRDAGETETHIFSQLAQDLVDVDQTKLVIAYEPIWAIGTGDTCETKEANRVIGLIRSKLSNPDVPIQYGGSVKPENIDEVMAQPEIDGVLVGGASLEVASFDRIVNYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3D1</accession>
    <name>A0A2G4F3D1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56256">
        <property type="protein sequence ID" value="PHX56256"/>
        <property type="gene ID" value="CP500_006205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="599"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="743" mass="81606" checksum="D87B94B8BAE02E55" modified="2018-01-31" version="1">MARRQSDKFSRPPEYNPFSEPTKLSAESVTSNDSSAAMTPPMVEGKRSFWQWQLIWLTVLVGFGVTGVAAFLWLLTMPPPPNCQQLSPLAADGERLYCAQQAAKSGKLEQLESAIVLVQAWPKEHPIYSQGQSLIGEWSKAILGFAKAKIEAGDLKGAMDIVAKIPKTSPSYPEVQEAVSAWENNWQEGQKLYDTAQAALKADDLKKAWDYAQTLFKLDNIFWSQKRYNELVQQIAVERNGWQRLEEARELAKDQTPQKFAEAIVLARKIDSKLFARAKAEEEIAGWSKILLAMANKQLQAKDLPGAIAAASVVPQDSPLFAEAQDLMQLGRALAVTWNQSITTPIGEHIFSLLEGQGAASQIASGRPLYEKAQTQIDNLEVQFQDLVRLQVANSIASIGLPGALAMAIEQAQTIGKSQPRRVHAQTLVASWRKEIQRIEDKSFVMLAKQLAEPGTVEGLKGAIAQVTLIAQNRPRRLEAQTLLASWTKRIEIVEDQPFLDGALALAKQGKLSEAIDKASQIKSGRTLYAKAQDNVYQWVTDLQVAEDQPILDRAAELASQGRLGSAIDMASQVSYGRALHSEAASAIGRWSAELSAKTAPLRAEPAPQAEPASVEEYAPAPRQEEYAPVPRQEYTPPPEPAPAPEPYYPPARQEPPAREPEPYYPPAREPEPYYPPARQAEPYYPPARQAEPYYPPARQAEPYYPPARQEAPAPAPAPEPAPAAPPPIPESAGSPDGNLIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3D2</accession>
    <name>A0A2G4F3D2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55987">
        <property type="protein sequence ID" value="PHX55987"/>
        <property type="gene ID" value="CP500_007815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="8927" checksum="32B287D36B172BF8" modified="2018-01-31" version="1">MKAIETTGTIDDRGMLCIDRPLALANRSHVRIIVLVPEDTDIDPDDDPTETVIEGIQQGFHEAITGQTLPLSQLWDGIDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3I9</accession>
    <name>A0A2G4F3I9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-6-phosphate dehydrogenase assembly protein OpcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">opcA</name>
        <name evidence="2" type="ORF">CP500_006040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56343">
        <property type="protein sequence ID" value="PHX56343"/>
        <property type="gene ID" value="CP500_006040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004555">
        <property type="entry name" value="G6PDH_assembly_OpcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38658">
        <property type="entry name" value="PTHR38658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10128">
        <property type="entry name" value="OpcA_G6PD_assem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00534">
        <property type="entry name" value="OpcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="62"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="453" mass="48857" checksum="671D15B92759BC09" modified="2018-01-31" version="1">MIMTPMKAPPLVSLQSPKDVSIDQIEAELAKIWESYRESGSKGDFPSATRATTFTFVVYEPEETQRLLADVGFYDGPIDGITGPMTASSIRAAQKAYGLPRTGKPNAELLATLREEVAKKNSSGSKLGPTGFGSGGSAVADAIVAANPCRIIALCPTIGEDTGVQAQVAAYCPVHKGGTGNLICCEYITLRGTEAALERVSGIVTALTIADLPTLLWWKATPDADRDLFQRLAATSSSVIIDSSCFAEPQAELLLMQSLIEEGIPIADLNWRRLAAWQELAAEAFDPPSRRAAIGEIDRVTIDYERGNSTQALMYLGWLASRLQWRPVAFKQEEGDYQIKRIKFAGVDERAIEAELAAIPTADTGDVPGDLIALRLNSTNENADCGTVLCSEAGGCMRMETKGGAQTDRFNQVTPLLDQVTEQLLGQHLQSWGRDVLYEESLAVTAQLLKLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Q9</accession>
    <name>A0A2G4F3Q9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Iron ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_005540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56413">
        <property type="protein sequence ID" value="PHX56413"/>
        <property type="gene ID" value="CP500_005540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040476">
        <property type="entry name" value="CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013223">
        <property type="entry name" value="RNase_B_OB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17876">
        <property type="entry name" value="CSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08206">
        <property type="entry name" value="OB_RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="3">
        <location>
            <begin position="690"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="789" mass="88323" checksum="65D88F685D4912F9" modified="2018-01-31" version="1">MEFSIAALLANFTEDKLVAPKALEKKLDCNDVTSQLKLQIALEALEKIGILVKDKGRYRRVTEDDVVEAKLRCSSKGFCFAIQDAEGSEDVYVRESHLSTAWNGDRVLVKIIKEGSRRRSPEGEVMLILERANPSVLARVKQTSTPTGNVSYRAIPLDDRLLFELDLLVNGTNLQEAIDHLVHVEVKRYPLGTHRPVGKVVQVLGSDAEAADDLDIVCCKHDLPRSFPAAVIKAAENLPSKLKKTDIKKRLDLRDILTFTFTKNQLEETESENIAETTQEEIISDFPKNEFDPASFLSNPPVERALSIETLKSGGWRVGVHIADAAEYVQPETPIDREARKRGTAPHLGDKIIAILPEILLDDRSSLIPDVERPTFSVILTIDESGELVEYEIQTSIIQVDCQLSYQEVETILESGTDATVHPLSSAICPFLNQLFAASEVVREARLKRGAFELNLPDANSHFDDEGELGAFAIAPRAQSAVSELVVLANQAVATHLQALGVPGIYRVQPMPDPADIQEFIKLSNNLGGELYLENEEEVLPFDFQRFTQQFAGLKSERVLTYLLEDTMKPAVYSTIPKPHFGLALQDGYTRCTSPLSRYADLLVLRLLQAVLEQGRSSRTTRAKEKVNLRHSSCHGQITWNVLPPDLHHEFETEFASLVVHLTERERVAEDAESDLQGLKKTGLMKERTGQNFQGLITGVQSYGFFVEIEVRPPESELLRVEGLVHVSSLKDDWYEYRSRQQTLVGRKNRNQYRLGDRVEVQVKSVDYYRQQIDLVAVGGGSQAFDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3S8</accession>
    <name>A0A2G4F3S8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR02652 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56412">
        <property type="protein sequence ID" value="PHX56412"/>
        <property type="gene ID" value="CP500_005735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013472">
        <property type="entry name" value="CHP02652"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09654">
        <property type="entry name" value="DUF2396"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02652">
        <property type="entry name" value="TIGR02652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="169" mass="20094" checksum="B3D6E3CE6B771151" modified="2018-01-31" version="1">MIEVALQYPMFGPEIQCPHCRQTIPALTLTDAYLCPRHGVFEADPKTGDLVHLQSGRHWRHWEDEWYRQHTHPDGIRFEIHEALDRLYTQGYRATRIIIAQRYRELISVYLERSTSWRGESESPMPKLYGLPVDFSPESQEEPCWEVINFDLEKEPGAPIRYPYFRLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3T0</accession>
    <name>A0A2G4F3T0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">dTDP-6-deoxy-L-hexose 3-O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56137">
        <property type="protein sequence ID" value="PHX56137"/>
        <property type="gene ID" value="CP500_007055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008884">
        <property type="entry name" value="TylF_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40036">
        <property type="entry name" value="PTHR40036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05711">
        <property type="entry name" value="TylF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="260" mass="29363" checksum="A16C9E4FE6EF343A" modified="2018-01-31" version="1">MFMTEENQITGLSHESKHTDEEKNLVGNLSKAFNSSTLPLPLKLQNFARHVRRQDVARMIAKYEIFKLSLPVNGSIVECGVFAGGGLMSWLHFSSILEPYNHTRKIVGFDTFSGFTALDSKDCDHGSSEHLHEGGFKTNDSIVDEIQHLVSLHDKNRPLRHIPKVELVPGDACKTIPSYVESHPHLLISLLYLDFDIYQPTKTALEKLYPRVVKGGIIAFDELNCPEFPGETTALLETLDLTQVKLCRFPFDPYISYFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F469</accession>
    <name>A0A2G4F469_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56583">
        <property type="protein sequence ID" value="PHX56583"/>
        <property type="gene ID" value="CP500_004885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="104" mass="11282" checksum="77FB603659E37E35" modified="2018-01-31" version="1">MNNLHNYRLRCTLTFGDIYGQIIIWLIVIFMSLASALALWSSARQIYALATVGLILVLSLPFLLFAFVTTLLNHIEVTAVEPANLAQPSASANLPGQKPAQAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F474</accession>
    <name>A0A2G4F474_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Malto-oligosyltrehalose trehalohydrolase</fullName>
            <shortName evidence="9">MTHase</shortName>
            <ecNumber evidence="3 9">3.2.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">4-alpha-D-((1-&gt;4)-alpha-D-glucano)trehalose trehalohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7 9">Maltooligosyl trehalose trehalohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">treZ</name>
        <name evidence="13" type="ORF">CP500_004670</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1 9">Glycan biosynthesis; trehalose biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.141" evidence="3 9"/>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56546">
        <property type="protein sequence ID" value="PHX56546"/>
        <property type="gene ID" value="CP500_004670"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00299"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033942">
        <property type="term" value="F:4-alpha-D-(1-&gt;4)-alpha-D-glucanotrehalose trehalohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022567">
        <property type="entry name" value="DUF3459"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012768">
        <property type="entry name" value="Trehalose_TreZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044901">
        <property type="entry name" value="Trehalose_TreZ_E-set_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11941">
        <property type="entry name" value="DUF3459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006337">
        <property type="entry name" value="Trehalose_TreZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02402">
        <property type="entry name" value="trehalose_TreZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="12">
        <location>
            <begin position="113"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="11">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006337-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006337-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX56546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="608" mass="69451" checksum="AA545CB9D85422AD" modified="2018-01-31" version="1">MKIGANYLGNNQCEFTVWAPTLTQVALQLVSPDKRLIPMQKSADGYWQTTAIDIPPGTLYTYQLEAKIDRPDPASKYQPQGVHCPSQVIDENAFTWTDTDWQSIPLAETIIYELHVGTFTQSGTFEAIIPQLNKLKELGINAIEIMPVAQFPGDRNWGYDGVYPYAVQNSYGGPEGFKKLINACHKQGISVILDVVFNHLGPEGNYLSDFGPYFTSKYGSIWGDPLNFDDAYSDGVRNYFIENALYWFRDYHIDGLRIDAIQAIFEVSARPFLQELSDATTDLSQQLGRQLYLIAESDLNDVRVLRPKELGGFGLDAQWCDDFHHALHTLLTGENDRYYQDFGKCEHLEKAFKESFVYSGQYAPHRKRKHGNSAKDQPAHQFVVFSQTHDQIGNRILGDRLSKIVDFEALKLAAATVLISPYIPFLFMGEEYGEEAPFLYFVSHSDKNLIEAIRKDKQQEFKVFEGRGEFQDPQSPDSFQKCKLNWEKPTAGKHKILWEWHQHLIKLRRTIPALKKLDKTSLEVSSIEAEKILFLRRWTDDSQIFCILNFNKQQVAFTVALPQGNWKKILDSADVKWMGAGSTLPEKITSQQELTVKPQSFALYELSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4F1</accession>
    <name>A0A2G4F4F1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2993 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56626">
        <property type="protein sequence ID" value="PHX56626"/>
        <property type="gene ID" value="CP500_004230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021373">
        <property type="entry name" value="DUF2993"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11209">
        <property type="entry name" value="LmeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="251" mass="27665" checksum="9B3F87166E5D03A2" modified="2018-01-31" version="1">MVAALFSGTSFQGQSGDRLVSKVAGAAIAALFKRSEKAEANIRVEPVAKLLQGSIDGFDFIGKGMLMYNGLRIEVMELYLQALSIDFGAIFAGQVKLRQPTQASMRVVLSKSDLTTSFNTPFVVEKLQRLSYQDKSLLFQNTEVSFGADKSIRLQSQVIVGHSSESVKIDITAQLQVEERRKIQFVSVTYGGDEAAVDLAKAIIVHVNNLLDLDKFALEGTQLRVDRCRVQNDELVFYGWAGIDHFPKGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4G4</accession>
    <name>A0A2G4F4G4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56628">
        <property type="protein sequence ID" value="PHX56628"/>
        <property type="gene ID" value="CP500_004240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033415">
        <property type="entry name" value="CHASE6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019278">
        <property type="entry name" value="DICT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17150">
        <property type="entry name" value="CHASE6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10069">
        <property type="entry name" value="DICT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="250"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="476" mass="53152" checksum="7FA79F595225A5CC" modified="2018-01-31" version="1">MNPESTLARLQATLPDGKLPSSYGVYFKNTLVALCHALEDHILQTSGGDDLELKPLVLVTFQQGKWYLQEADRYFDIANASRRVVIGAVADSGFATHKTGQLENVSLINIDPIDPIVAEWNLIILAPTYKAMVLCRELSHKEYLPEGKPEVDTERKFYGLWSFDQSLVSAAAEIFIEQTRHYDRHLADKLLQIHQEILATIGPPLADISGVVTRIVTYLQSSQQQMVAINRQSRDLWELEGQALRISRNLNANKLQAFLRMAQRVDERDGSNPTASLQVAALSETLGQLLDLPTLQLRRLRLAGLLFRVGLVSAPNEVFTQTSDQFDQQTLAFWRDRSFIGSQLLQAMPELAPVAEIVKHKLEHWDGSGRPEGLRGEETPVASRILGLVACFQDWTQARGDRPALGLTAAWEKCRDISGTRFDPALVETLGNVVRLAEMGLMELPTRPSQLPNVWLEDLGDRAPSVTTDNKQLTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4R0</accession>
    <name>A0A2G4F4R0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SMC-Scp complex subunit ScpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">scpB</name>
        <name evidence="4" type="ORF">CP500_003910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56783">
        <property type="protein sequence ID" value="PHX56783"/>
        <property type="gene ID" value="CP500_003910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019345">
        <property type="entry name" value="ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00281">
        <property type="entry name" value="TIGR00281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="171" mass="19179" checksum="8D060BFAC79FEDA2" modified="2018-01-31" version="1">MTRLATTIEAILYLKGQPVSIAEIAEIAKCDRTDVEDAIIELMSDSAHRDSALEVVETPTGYSLQLREEFASLMQTLIPPELGIGALRTLAAIALKGGIAQPDLVNLRGSGAYQQVQELVELGFVRKRRPSESRSYWLQVTDKFHRYFQVDQLPKQLQIEFQANLYPSNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4U2</accession>
    <name>A0A2G4F4U2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56813">
        <property type="protein sequence ID" value="PHX56813"/>
        <property type="gene ID" value="CP500_003405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="9120" checksum="D22BBD44581F153E" modified="2018-01-31" version="1">MSNATQKREVLVALDAEFADKIDQLTDNWTEAIEQALRLWYAKKIEDKLRNFYEKRSQEDIEFEEDWATFAQSQME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F569</accession>
    <name>A0A2G4F569_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleotidyl transferase AbiEii/AbiGii toxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56875">
        <property type="protein sequence ID" value="PHX56875"/>
        <property type="gene ID" value="CP500_003100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="319" mass="37085" checksum="3307900415867450" modified="2018-01-31" version="1">MKMFEHPDFRDAVIAAREHFDRFGLTEQFIEKDYYVTSALRIVANQWRTQVIFKGGTSLSKGWKLIERFSEDIDLFLNKQAFVPPLGANRIDQELAAIESAVGEHPALTLEPDSSKRKRGVFRNSYFSYTQQFSGNQAIANRVFLEMGTRSGTYPTQTVQLSSYVAEFLREIGQSLDTEDELPFSMLLLDFRRTFVEKLFAIHSKVVKIQQDGQSIGTYARHYYDLFCLAQKSEVRQMFQTEEYSQIKEDCDRISREHFPDYQPPSAMKFSNSSALFPTGELRQTIAREYEQQCGRLCYGNYPTWEEIEACFEELRDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5L1</accession>
    <name>A0A2G4F5L1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="5">4.1.2.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Queuosine biosynthesis protein QueD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_002240</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.50" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57028">
        <property type="protein sequence ID" value="PHX57028"/>
        <property type="gene ID" value="CP500_002240"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX57028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="290" mass="32939" checksum="716C6F622BA34746" modified="2018-01-31" version="1">MQCIINRRAQFSASHRYWLPELSEAENFERFGPTARAPGHGHNYVLYVSMIGKLDEYGMVLNLSDVKHVIKREVTKDLDFSYLNEAWPEFEQTLPTTENIARQIWLRLAPHLPLSKIQLFEHPELWAEYLGNGMEAYLTLSTHFSAAHRLARPDLSFEENSEIYGKCARPSGHGHNYHLEVTVKGEIDARTGMIADLGALQKAIDDYVVEPFDHTFLNKDIAYFENVVPTAENIAVRIGQLLRSPIRELGAELHKIKLIESPNNSCEIYGADLEELVAERQQPEAVLAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5X3</accession>
    <name>A0A2G4F5X3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57193">
        <property type="protein sequence ID" value="PHX57193"/>
        <property type="gene ID" value="CP500_001330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="524" mass="52257" checksum="CC994D7E20C9A534" modified="2018-01-31" version="1">MANLIGTDSNDFLLGTPQGDRIRALDGDDTLLGVAGDDTLEGDNGNDQIIGGDGADSLFGGEGNDEIIGNQGRDTASGGNGDDSIRGGLGNDILNGNDGSDTVFGDAGDDLVRGNAGFDVIAGGTGNDTLTGGDGDDSVFGNADDDFLYGEIGDDSLNGGSGSDQLFGGDGKDYFRGEDGSDTLYGGAGTDSLYGDGGNDQIFGGKANDTAIGGTGSDTIRGDEGQDLLQGGEDNDFLFGGKGSDVLDGGFGDDSLAGGLGDDTLLGSFGNDNLFGAEGNDCLSGGEGSDTLTGGSGSDIFVLGAGPGSLALITDYNEAEDFFGLPTNLSFTDLVITQGNGANRRDTVITTKKDGKLLAILIDTPAGLIEATDFVSVTGTVPVRPTTTTVTTTVTTTISDPTVATTPTPTPTPTPTPTPTPTPTPTPTPTPTPATTPTPATTPTPATTPTPATTPTPATTPTPATTPTPTASRIPSPPTISLPDSPLLSIKSIAPTPTPGLLGMSSPTPIFPSAWPTPPTPFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F646</accession>
    <name>A0A2G4F646_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57263">
        <property type="protein sequence ID" value="PHX57263"/>
        <property type="gene ID" value="CP500_001080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="198" mass="22738" checksum="F95BE340329EA354" modified="2018-01-31" version="1">MLLLDPKTLAPATEQRVILYDVTWEQYVQLSDMFVDDFPRMTYLEGTLEIIMTTSPEHERLKTIIARLIETYAVEKLINLNGYGSATFRREAVRRGAEPDECYCLGTLAEIPDIAIEIALTSGGIDKLEVYEGLQVPEVWFWVNNQFSVYHLREEGYELISRSDFLPELDLSVLSQYVGYINQTEAVIAYRTVLQTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F648</accession>
    <name>A0A2G4F648_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_001085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57264">
        <property type="protein sequence ID" value="PHX57264"/>
        <property type="gene ID" value="CP500_001085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070122">
        <property type="term" value="F:isopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028090">
        <property type="entry name" value="JAB_dom_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14464">
        <property type="entry name" value="Prok-JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="6">
        <location>
            <begin position="4"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="153" mass="17427" checksum="7650A1B2DC35B6A1" modified="2018-01-31" version="1">MQPIALSDSHILSIRTHAENTYPEECCGLLLGTIASNIKTLVEVWPTKNAWSAEAEHNWPEQKVLTEKRRYAISPADMLKAMKDARDRNLEIIGIYHSHPDCAAVPSECDRTLAWPQYSYIIVSVQQGRSEDLRSWSLDTESNFQAEEILRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F653</accession>
    <name>A0A2G4F653_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proline--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="8">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">proS</name>
        <name evidence="10" type="ORF">CP500_000930</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57236">
        <property type="protein sequence ID" value="PHX57236"/>
        <property type="gene ID" value="CP500_000930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00779">
        <property type="entry name" value="ProRS_core_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01569">
        <property type="entry name" value="Pro_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023717">
        <property type="entry name" value="Pro-tRNA-Synthase_IIa_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044140">
        <property type="entry name" value="ProRS_anticodon_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033730">
        <property type="entry name" value="ProRS_core_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="33"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="601" mass="67104" checksum="45857551DB09769C" modified="2018-01-31" version="1">MRLSQMLFVTLREDPAEAEIPSHKLLLRAGYIRRIGSGIYAYLPLMWRVLKKVSQIVREEMDATGAQECLLPQLQPADLWRESGRWDTYTQAEGIMFALTDRRDTELGLGPTHEEVITTIAKDMIRSYRQLPTHLYQIQTKFRDEIRPRFGLMRGREFIMKDGYSFHTNEESLKKTYQDMAQAYSNMLRRSGLQFRAVDADSGAIGGSGSQEFMVLAEAGEDEVLYTEDGQYAANLEKAVSIPADAETSPFASFEKRETPGTETIEKLCKFFKCSPTQVVKNVLYQAVYDSGITVLVLVSIRGDQDVNQVKLLNELTKLAGNYQGKTILFLTVPDAEAQQKWASKSLPLGYMAPDVADDYIAGSKEVNSKFLRLVDRTAVDLTNFVTGSNESGYHVVGANWGKEFPLPSLAVDVRKAKKGDRAVHNPEQTLQTARGIEVGHIFQLGTKYSQAMGATYTNEQGEEMPLVMGCYGVGVSRLAQSAVEQSYDKDGIIWPVAIAPYHVIISIPNISDAQQVEVAEKLYTELNQSGIETLLDDRDERAGVKFKDADLIGIPYRIVPGRSLKAGKVEVVERATHKSQEIPIDEVNSTLKNWIEAAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F655</accession>
    <name>A0A2G4F655_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_000950</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57240">
        <property type="protein sequence ID" value="PHX57240"/>
        <property type="gene ID" value="CP500_000950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="8"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="81"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="207"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="503"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="776"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="740"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1027" mass="114358" checksum="2F1C37C455765720" modified="2018-01-31" version="1">MKDSQYIENSLLESILESTADLIFVKDTQGRYVSLNSKTAAFFGKSKAEVIGKTDTDFFSPEIVAKLVEIDRRVIQSGIEETVEEVVEDIDGNLQTYLATKSPWRDREGNIIGVVGVTRNISDRKIAEEQLRQKEEFLRSIYDSVDYSIFVIDVGADGEFRYAGWNQAAELLGNISSEFGCGKTPEELFPGPTAAFLLQKLRECLQKNSSISYEEAVSFDTIEVWFLITLNPLRDESGKIFRIVGSATEITYRKKAEQALAEQLKLSVFRADVGIALTDNQILPVILQKCCDAVVRHLDAAFARIWTLNEDENVLELEASAGMYTHINGDHSHIPVGQFKIGLIAKERKPHLTNAVMEDPRVSNKEWAEREGMVAFAGYPLIVDNQLVGVIAMFSRHELNELTLIALASIADVIALGIKRKQIEVALAKQKQTLRGIIDNAPIWVWMTNINGRMLLVNKTFCEDVAIPEDKFLAATHYSEVLGVEASANYMASDLQAWSQDTPSYSEEVMQLADGEEHYLETIKTQVKDAYGNAIGLIGLGLDVTQEREAQKRLQESEARFRKLAEQEALLNQLASNIRASLDLDTILATTVRQVRELLQVDRCLFVWYEPDASPPVWNVTYEAKNPDLPSLLGLYPTEATGSHAALIANLEIIRIDDFDTVTASVERDFFISIGFNSLLDIPIQTLSSQIGLICCTTCGVPRHWSDDEVELLVAVGNQLTIAINQAELYTQSLDSARIAREQAAKLETTLCELQQAQTQLVQAEKMSSLGQMVAGIAHEINNPVSFIFGNISYIKEYTRSLIKLLEMYRDEFPEAPPAIQSEMDALELDFLLDDLPKILSSMKVGAIRIRDIVRSLRSFSRLDESAMKSVNLHEGIDSTLMILEHRLKAQSDSPLIQVVKEYGELPLVECYAGQLNQVFMNIIANAIDAVEEQKSNPGIIRIRTEVEGTFVAIAISDNGTGMTDQVKQRIFDPFFTTKAIGSGTGMGLAISHSIIVEKHKGEIKCFSVVGKGTEFIIEIPIKRTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6C8</accession>
    <name>A0A2G4F6C8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycine-rich domain-containing protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57299">
        <property type="protein sequence ID" value="PHX57299"/>
        <property type="gene ID" value="CP500_000500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009836">
        <property type="entry name" value="GRDP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365">
        <property type="entry name" value="PTHR34365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07173">
        <property type="entry name" value="GRDP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="190" mass="21923" checksum="EC7F79E916F586FA" modified="2018-01-31" version="1">MSVEQKVVRAEVQVFLNKLRTVDLGPIAYKLMHPEKGRGWTKAKTVRAIARYMAFLGLIYLYPDRPFVPTQEIDAVWHNHILDTTKYHQDCELLFGRYVHHFPYFSLRGEADEQNWQAAFAETQTIFKQHFGIAPSDKLDRSKIWLKAEEKKKEGARCSNLKDSDSKKTGNRPTVDIKAEVLAVFPEALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6F4</accession>
    <name>A0A2G4F6F4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000805</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57352">
        <property type="protein sequence ID" value="PHX57352"/>
        <property type="gene ID" value="CP500_000805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040576">
        <property type="entry name" value="DLP_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18709">
        <property type="entry name" value="DLP_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="58"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="DLP_helical" evidence="3">
        <location>
            <begin position="390"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="325"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="585" mass="65738" checksum="0A63E78B3583FDDD" modified="2018-01-31" version="1">MTHNNPNFKAADVGAFFNKTLVKFESLLDQGNTAELTAIRQKVDDELKEYQEQGILGVAFVGQYSAGKSTIISGMTGRRDIRIDADIATDKTTNYDWNGIKVIDTPGLFTDRQDHDEITYEAINKSDLLVFCLTYMLFDSLTAENFKKLAYEKGYRWKMMLVINKMSDEAGEEEQKISNYRQSLADALKPYSLDEFPICFIDAKDYCEGIDGKDDFLTEISRFPTFIEALNQFVERRGSLARFDTPVRIALSCIDDAQSSFTRNSSEDSAFFEVLNRLSRTVRKERDRLRTKVKNIALEMSSGVASEGNTLAAAVGSDQNFERLNKQAELNVQKHYEKAENKLQEAVNVAVDEIQQEVEKVLEGDLVKSFVACLDKSQNISAQNLGAGMDVERLKSQVNWFKSIGETAGVNLTNLATRGFVETASKQGFLRSIDVVGGSLHQGVLAVGKFVGFKFKPWQAVGMAKNIGNAAKFLGPALAIVSVGVDILQMQQEHERERQMADVRRDITSQFQSIAKDLENQIEIQLFDFEQQVYGEIENKIAAARQNQEEVIYASNTWVKQLAEIRKDFDVIIQYITKAVANPNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6I0</accession>
    <name>A0A2G4F6I0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57360">
        <property type="protein sequence ID" value="PHX57360"/>
        <property type="gene ID" value="CP500_000580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10930" checksum="6BA1C8E1EC0518CD" modified="2018-01-31" version="1">MEIHELVVEMKLLERRLTLYEEKYGVLSEDFYKALFAGDLARYDEYDETRTDFSRWKGIYETWLRRKGSYTEQIDQRELADTLRFQPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6N9</accession>
    <name>A0A2G4F6N9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5678 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57418">
        <property type="protein sequence ID" value="PHX57418"/>
        <property type="gene ID" value="CP500_000330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043734">
        <property type="entry name" value="DUF5678"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18929">
        <property type="entry name" value="DUF5678"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5678" evidence="1">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="9314" checksum="7F723F3AA7AC2871" modified="2018-01-31" version="1">MEAEYTTAEEWYKANRRELKKYRGQWIAYTKKGVISCDRDYRKMKDGIPADVPKLGYVLDRIHESEFVEPVRFPGFHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F742</accession>
    <name>A0A2G4F742_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57437">
        <property type="protein sequence ID" value="PHX57437"/>
        <property type="gene ID" value="CP500_000435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="95" mass="10094" checksum="C610A4698C66C3C7" modified="2018-01-31" version="1">MSILPNFLRSLLLTSLLSFVAPLLLIGAGLTGFSLIGLVPYLQGLGHSGEDLILQFLATFGSGCPLQGFLVIGMTFGLVGALFDTYASFDHSRWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUD5</accession>
    <name>A0A2G4EUD5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_023080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000263">
        <property type="protein sequence ID" value="PHX53145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53145">
        <property type="protein sequence ID" value="PHX53145"/>
        <property type="gene ID" value="CP500_023080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="19053" checksum="979DA9B3FDA29ABC" modified="2018-01-31" version="1">MIASVFPFRTVLVQVLILFLAIAIESWFLQKLIKLGPKTSVEYTAILNLCCTCIGWLLFFGIESVLPKDLREQLIDYMILGGGQDIYSAITAIAVLVLAITFFAKWQGLELIQNVATGTKKASKPQFIGPPTLTKRPPQKTFQVTTIFGAVLIAHTVSNFVILTVLFLQSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUH6</accession>
    <name>A0A2G4EUH6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Molecular chaperone DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000249">
        <property type="protein sequence ID" value="PHX53185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53185">
        <property type="protein sequence ID" value="PHX53185"/>
        <property type="gene ID" value="CP500_022865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="16"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="308" mass="34784" checksum="42CBE571B33BBEEE" modified="2018-01-31" version="1">MSFEMTHGLFKFDFTDQHAILGVPLDAEFNDIRKRYMKIVRRLHSDTCPFEDQADKDWANQFLSKVVNPAYNMFSKEGDRKEYTLLLTAIAKRAAKEPQKPQVESATAKQLATAGNWEELYKTEVNKLSEKQYESVEQALEVINQISELNMVYLLRKENVIVSTGGGVPTHPTSVEKDSKTVNPATSVAHLPPPKKDSEMDKYCRRAQGFMDSKNFAKATLELREAQKREPKNSKCHAMLAMCYFQQGQATMAKLEMQKALASNPEEPMALEVKKKLEQPASAKTKKGDDKPAGFFASFTNLFGGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUN5</accession>
    <name>A0A2G4EUN5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Paraslipin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000230">
        <property type="protein sequence ID" value="PHX53249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53249">
        <property type="protein sequence ID" value="PHX53249"/>
        <property type="gene ID" value="CP500_022515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="20"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="279" mass="31340" checksum="E90F99CCB542F1AC" modified="2018-01-31" version="1">MGQSILAMLVALILGYAVNSSVKIVSGGDEALVERLGQYKRTLKPGFHFISPVVEKVVCVDTTRERVLDIKPQSAITVDNVVLDVDAVVYWRVVNLQKAYYGIDQIENAIANLVLTTFRGEIGRLPMKEIFGSRDEMNKQLLKKLDEATETWGVKVIRVEIQSITPPKRVQEAMELEQATKSEWQAMVNKATGTKEYMKLLVEALDSHPNSKQVLNYLVTEKYLDAQQKLGESDNAKILFMDPKNMTEALNELMGSMSDIKPHSPHEDMKVIDTQATQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUQ1</accession>
    <name>A0A2G4EUQ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_022995</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000256">
        <property type="protein sequence ID" value="PHX53160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53160">
        <property type="protein sequence ID" value="PHX53160"/>
        <property type="gene ID" value="CP500_022995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021731">
        <property type="entry name" value="AMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11741">
        <property type="entry name" value="AMIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013585869" evidence="3">
        <location>
            <begin position="23"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="MurNAc-LAA" evidence="4">
        <location>
            <begin position="377"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="492" mass="53319" checksum="40E638AB5EEE0CF0" modified="2018-01-31" version="1">MKFHWLLSSFLGVFLLTGAAEAARLQSWRFDASQNRLYITTDGGVQPKAQLIFNPTRLVIDLPGTSLGRQSVNQPYSGAIESVRLGQFDDDTTRIVVELKDGYTIDPSQVKFRGLSPSEWTVDLPTPVRAGNPNSSSELGGERLSVESSAPSSQTAAATVIQNIQVTADGFLIRTAGGRPQINFQQSRAGDIATLDIEDATLSPGLSNQQPQTNGKHGVERIEVRQLPTEPPMTRVTLRMKSSNTQWRASLSSLGGISLLPAGVRQSATPRPLTVDPPIRSSVSVPPPLAQNRNPISWPRTNTGTTDLPQVSNSRRVVVIDPGHGGRDPGAVGIGGIQEKEIVLDISFQVARILEQQGVQAVLSRTDDSEIDLEPRVSLAERLNATLFVSIHANAINMSRPDVSGIETYYYGSGLDLARVIHNSILEGTGAADRRVRQARFYVLRKTTMPSVLLEVGFVTGAEDAARLSDPAYRSQMAASIARGILLYLQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUT9</accession>
    <name>A0A2G4EUT9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_022145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000217">
        <property type="protein sequence ID" value="PHX53312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53312">
        <property type="protein sequence ID" value="PHX53312"/>
        <property type="gene ID" value="CP500_022145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="237" mass="26633" checksum="C3DC44B223BF9004" modified="2018-01-31" version="1">MILALSFRAIRRTQSLHEQTYQALRTAILSGELAGGERLIETQLAEMLNVSRTPVREALCQLQRENLVTADPHHGLRVATLSIADAADLYDCRIALEQLSATGASQNATLTQLQQLESIVLQAENNTQARSGELTNYQLLYADYQFHRLLAQSSGNSWLVTLLDQVFDKMILVRLRTMEYNPGVLEIRSEHRRIYQAVSEQNPAAAGEAMKEHLIASKARVIKEIQEIDQQHGKIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV54</accession>
    <name>A0A2G4EV54_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP(H)-dependent aldo-keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000200">
        <property type="protein sequence ID" value="PHX53419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53419">
        <property type="protein sequence ID" value="PHX53419"/>
        <property type="gene ID" value="CP500_021570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="345" mass="38942" checksum="5C6235ACDEDADA54" modified="2018-01-31" version="1">MEYQKLGDSDLSVSEICLGTMTYGQQNTVEEAAKQLDFAIDRGVNFIDTAEMYPVPTKPETQGKTEEYIGEWLVNQQRDKIIIATKVAGRSSRLKWIREGKNQIDRQNVEKALNDSLKRLQTDYIDLYQIHWPDRYVPLFGAPDYDIAQEHETVPILEQLEVFAELIKAGKIRYLGLSNETPWGVSEFCELAEKHGLPKVISIQNAFSLSNRTFHMNLAETCRFKNVGLMAYSPLGFGILTGKYLNGIPDNSRLALFAGFGQRYDKTNLNDAVKAYVEIAGKYNLTPARMALAYVRSRWFVTSTIIGATSLEQLEENLSSLDVTLDKDIIAEINAVHAKYPNPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVE6</accession>
    <name>A0A2G4EVE6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">EAL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000202">
        <property type="protein sequence ID" value="PHX53410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53410">
        <property type="protein sequence ID" value="PHX53410"/>
        <property type="gene ID" value="CP500_021705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="54" mass="6258" checksum="EE2ED62957A657A0" modified="2018-01-31" version="1">MNQDDFGNGYASLSYLSRFPTDTLKVDRSFVGRRLGFRIAIVRICYFNCINMSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVH0</accession>
    <name>A0A2G4EVH0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CbiG_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000181">
        <property type="protein sequence ID" value="PHX53542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53542">
        <property type="protein sequence ID" value="PHX53542"/>
        <property type="gene ID" value="CP500_020970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002750">
        <property type="entry name" value="CobE/GbiG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036518">
        <property type="entry name" value="CobE/GbiG_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01890">
        <property type="entry name" value="CbiG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159664">
        <property type="entry name" value="SSF159664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiG_C" evidence="1">
        <location>
            <begin position="21"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="162" mass="17101" checksum="D1D22A4E68E16DFD" modified="2018-01-31" version="1" fragment="single">MPYALCPMPHAPCPMPNSRVLWIGIGCQRGISRELIETAIQQVCHSYDLAESAIAGIATIDTKANETGIIELCQQRNWALKTFPANTLNSVEVPNPSDIVAKGVGTYSVAEAAALCAIELTSCTILKNRQDACSTKSESACGTGILPYCGVGILPYCGVGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVH2</accession>
    <name>A0A2G4EVH2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000182">
        <property type="protein sequence ID" value="PHX53533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53533">
        <property type="protein sequence ID" value="PHX53533"/>
        <property type="gene ID" value="CP500_020990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="254" mass="25125" checksum="A86D4ECD13AE5F61" modified="2018-01-31" version="1">MPTATPFQIIPKSTPTPAPSGTTTNSGGTTVSRSGISGTSGPDSLSGTTGNNSIFGLGGADTIFGLAGNDTIYGEGGDDSIRGDAGNDCLFGGSGRDSMFGNEGDDTLYGGKGADSQSGDDGNDLLLGNQDSDTLLGGAGNDTLFGGSGDDSLFGGAGDDSLSGDRGKDTLTGGIGNDTFVISPSSDGDLIIDFTDGGDRIRLGAGLTFAELTISAGISGTTPSTIIQLTSTKENLATLFGVSSSLISRTDFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVL7</accession>
    <name>A0A2G4EVL7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000242">
        <property type="protein sequence ID" value="PHX53207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53207">
        <property type="protein sequence ID" value="PHX53207"/>
        <property type="gene ID" value="CP500_022710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="397" mass="45071" checksum="BC50E2D556DFC3B2" modified="2018-01-31" version="1">MSKYYIFFTRNVLPQPNVASLVQVTHSANAAANLGYPAVLVYLRKGWSAFNPVDLLHHFQPRKPDEKLAKIYNIQDKLKVADLPMPWPIDLLDSKWTSSSTIVSKYYLPIHLKSTQIVHTRDWNFVKAAIKNGIPAIYEQHHHESKQFEPEIVRNPLFQISVTVADTVRDSMIQNGMPPEKVIMLHNGFNQLFLARQRAETIIWRQKLLGDGREHLAVYAGGLYPFKGVDMLVDVAGELPEVQFAIAGGDLSQVTTYQQLAKDKQVNNIKFLGYLPQNQLASLLQAADVLTHPHCLTEAATFTSPLKFFDYMASGTPIVATEIPSLLEFKSGNIAATWCTPDNPYQFAQSIQASLTKYPRKVEGYAETMDFVKQFSWENRIERILSYVDEKVRYPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVL9</accession>
    <name>A0A2G4EVL9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000192">
        <property type="protein sequence ID" value="PHX53480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53480">
        <property type="protein sequence ID" value="PHX53480"/>
        <property type="gene ID" value="CP500_021315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="17777" checksum="7C374B07538BD67E" modified="2018-01-31" version="1">MDELSAKALLEDLKNSDETVRDRATTELWRCWFHQKGEYGMQILRRSQVSLDAGDVRHALDLLTKLISEEADFAEAWNRRAVLHYTQGNYKKSIQDCEVVLKLNPIHFGALHGLGLCYAALGEYISAIQAFRRALEIQPFALVNQKLILECTARLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVN6</accession>
    <name>A0A2G4EVN6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53595">
        <property type="protein sequence ID" value="PHX53595"/>
        <property type="gene ID" value="CP500_020700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="128" mass="14072" checksum="BED93986B57606EA" modified="2018-01-31" version="1">MNGIQCIVRLGVGAIMIWMTLLRNTEIKMAIEKYEDQTIAAGFLVALTLREGTAPLRSYVGEVQTVDGNGIRLTLIDWISLTMSGSDLFVPWSNIEAALIATPEHDSDIFVKEAEAWQKSVSSKKSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVP4</accession>
    <name>A0A2G4EVP4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein PsbN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">psbN</name>
        <name evidence="6" type="ORF">CP500_020560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May play a role in photosystem I and II biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cellular thylakoid membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PsbN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Originally thought to be a component of PSII; based on experiments in Synechocystis, N.tabacum and barley, and its absence from PSII in T.elongatus and T.vulcanus, this is probably not true.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000173">
        <property type="protein sequence ID" value="PHX53605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53605">
        <property type="protein sequence ID" value="PHX53605"/>
        <property type="gene ID" value="CP500_020560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00293">
        <property type="entry name" value="PSII_PsbN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003398">
        <property type="entry name" value="PSII_PsbN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35326">
        <property type="entry name" value="PTHR35326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02468">
        <property type="entry name" value="PsbN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="43" mass="4624" checksum="1EDD47923A9E1323" modified="2018-01-31" version="1">MEPAAVLGISLGLCLVAMTGFSIYTAFGPPAKELRDPFEEHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVU6</accession>
    <name>A0A2G4EVU6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Eco29kI family restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000167">
        <property type="protein sequence ID" value="PHX53653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245908">
        <property type="entry name" value="Tbo703ORF20360P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53653">
        <property type="protein sequence ID" value="PHX53653"/>
        <property type="gene ID" value="CP500_020365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018575">
        <property type="entry name" value="Restrct_endonuc_II_Eco29kI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09517">
        <property type="entry name" value="RE_Eco29kI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="214" mass="24377" checksum="FE2C3C5FEFFF0BF9" modified="2018-01-31" version="1">MKSTSFDKNKHLYKSEAFVELVKDAVRFFNGTPVHTLQLPEAFLGTGVYALYYIGQSPLYKQYSELNRLAYNCPIYVGKAVPKGWRQARISDSVLNRSRELCNRLREHSRSITTGGGLSIEDFMCRFVIFEYEGSDMIGTIEAALIKLNQPLWNVAVDGFGNHDPGRGRYEQAKSDWDVIHPGRPWAERCNGTYKDESTIFANIERHLKSVGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVW1</accession>
    <name>A0A2G4EVW1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Two-component sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_022180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000217">
        <property type="protein sequence ID" value="PHX53317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53317">
        <property type="protein sequence ID" value="PHX53317"/>
        <property type="gene ID" value="CP500_022180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041610">
        <property type="entry name" value="ArlS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18719">
        <property type="entry name" value="ArlS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="226"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="443" mass="49157" checksum="9070FAB7CABF0764" modified="2018-01-31" version="1">MNQNKLFNRTRSQLAISYAAVMGLILSLLGFGVYKAIAHAHWVAIDRELESVAGTLHDSLEIKLQQPGRLEPIVNELLPNLRVIGVNGIKEQLPSRHILSAINQGYYYIRLFDCSGKLIATAGAYPEQLPPDFNSKYWQTISDLKGNIYHQISVSLHTKTQQNWGYFQVGRSLQDFNDYLNTVRWVLKLGLPTALILIGFSSWLLAGLAMKPIYASYRQIQQFTADAAHELRTPLAASQATVESALLMPELDEKEAREILRTIDRQNRRLTQLVADLLLLARMDHQSIPDRPQLCCLNDLVSDLVEELAAMAIASKVALTSEVRTQQQLNVVGNSDQLYRLVANLIVNAIQYTPAGGKVTVILDSSHTDAIIQVQDTGIGIGAADMGRIFDRFYRVNSDRSRHTGGSGLGLAIAQTIARAHRGSLTTRSELGFGTTFLLRLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW16</accession>
    <name>A0A2G4EW16_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PEP-CTERM sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53721">
        <property type="protein sequence ID" value="PHX53721"/>
        <property type="gene ID" value="CP500_020000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027372">
        <property type="entry name" value="Phytase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13449">
        <property type="entry name" value="Phytase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phytase-like" evidence="1">
        <location>
            <begin position="54"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="375" mass="40802" checksum="CFED39D992B3DF51" modified="2018-01-31" version="1">MRKSAKLILFIVCILISATVAIFVGMSAQSFAVTQIDFIGRAIFPTGSPFGGTEIGGLSGITYDADKQVYYTISDDRSTLAPARFYSLKINLPSGKLEKEQIAFTAVTTLLDENGKSFPELSLDPEGIAFTGNSVFVSSEGDVDRRINPFIKEFSLDGKLLKTLSIPDLFLPDDKGTKGIRNNLAFESLTLTPDKKYLFTATENALVQDGAVPSLQSGSPCRILQYDAVSGNLGRSFVYITEPLPPGANPVGKFTTNGLVDLLAIDENRLLSLERAFSLETGNIIRLFEISLEKADRIFGLESLKSRLSEVSPAQKRLLLDFDTLKIPLDNIEGLTLGPVLGDGSRGLILVSDNNFSPFQETQILGFKIKVQKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW33</accession>
    <name>A0A2G4EW33_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General stress protein CTC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplY</name>
        <name evidence="6" type="synonym">ctc</name>
        <name evidence="8" type="ORF">CP500_019935</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000159">
        <property type="protein sequence ID" value="PHX53734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53734">
        <property type="protein sequence ID" value="PHX53734"/>
        <property type="gene ID" value="CP500_019935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_L25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_L25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_L25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_L25_long"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_TL5_C" evidence="7">
        <location>
            <begin position="102"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="196" mass="21099" checksum="065FBD00AC59F777" modified="2018-01-31" version="1">MQIAVECQKRAEGSKPNALRRSGLIPAVLYGHKGCESISLTIPAKAVENLLKQRVINNVLIDLDIPEISWKGKTLLREVQRHPWKGFPYHLSFFAVGSQDSLEVELSLRFVGESVGVKMGGGLLDTVMMQLTVKCKPDSIPDAIEVDISNLNVGDALHIHELVLPAGVVAVAEPNQVVVSVLGSQGSSEEASETPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW96</accession>
    <name>A0A2G4EW96_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_019495</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53804">
        <property type="protein sequence ID" value="PHX53804"/>
        <property type="gene ID" value="CP500_019495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="Gdt1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="10038" checksum="92D31B6162BF04B6" modified="2018-01-31" version="1">MDWQLLGITFITVFLSELGDKSQVAAIALGSSCESPRAVFFGTASALLLASFIGVVVGQGTAQVLPASLVKGIAAIGFAVMGVRLLWPKADVPEESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWC8</accession>
    <name>A0A2G4EWC8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_019295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000149">
        <property type="protein sequence ID" value="PHX53845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53845">
        <property type="protein sequence ID" value="PHX53845"/>
        <property type="gene ID" value="CP500_019295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="191"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="448" mass="51197" checksum="42B196950D57FB10" modified="2018-01-31" version="1">MFALHEFSSELSELYIPEICTWNLSLESTLLDLPLYNCQIELTQQAIEVAHTFEKKPLLPGVILTDRGNFVGIISRRLFFERISRRYGLEMFFKRPIEVLYRFSRKEMLILSGSKLILEAAEESLYRSAELVYDPIVVEVVPETYWLLDVHQLMVAQSKIQQLTNKLLQKQTEAKLIQTEKMASLGNIIAGVAHEIRNPLNCIWGNLNFLLSYFEDLLVLMSAYEEEFPEPSSIIDEIKEKIEFDFLREDLPATLEGMKFGAEQLLKIVNGLHNFSHMDESKPLNTDIHECLENTLLILKNRLKQGIEVVKKYGELPLVICYSGQLSQVFLNLLVNALDALAEYTADQETNGQYQQHWHPRIEITTKIIEIEDRKWAAISITDNGPGIPPEIQQQIFETFFTTKPVGKGTGMGLAICNQIVTEKHGGKLNLRSQPAPNTEFEILLPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWD4</accession>
    <name>A0A2G4EWD4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000149">
        <property type="protein sequence ID" value="PHX53843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53843">
        <property type="protein sequence ID" value="PHX53843"/>
        <property type="gene ID" value="CP500_019285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06974">
        <property type="entry name" value="TerD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003325">
        <property type="entry name" value="TerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02342">
        <property type="entry name" value="TerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TerD" evidence="1">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="668" mass="70767" checksum="B3238BAEEE99AA2D" modified="2018-01-31" version="1">MSIELTKGERFNLSQEVPNFNKLAIALGWQISQTAQNCDIDASVFMLAADGRIPDEKYFVFYNNLTSPDGSVRHSGDSRSGQVEGDDETVYVDLSKINSAIQEIVFVVTLHEGQEKNQSFSQVTNAFIRLYNSETLGELVRYNLNQIFSQETALEFGRLYRKNGDWRFQAVGQGYNAGLQSFVDKYYVENAVTQGANAGGKVDDAEVLRLFSDRVDRLLREESVSSEAVEQPIATPVNADIVQSEEEAKIDDSGLESLEPAISAEEFLQRYNQGERDFMGVNLAGVNLSGKSLGGVNLSSANLCGAELSKAYLLGANLSEANLSHANLHKANLESSNLDKAQLLNANLSEVNLLYANLSEANLSGLNLSDVNLSQGMNLSRANLSNANLTGLNLRQSQLMNADLSNANLSNANLFKANLEGANLEGAKLEQALCNAQTILPIGFDPIKAGAYLIVADASLPNVNLAGVDLNCFNLSEANLSGANLTKANLAAAKLLQANLSAANLSEANLNGADLTTANLSEANLSTANLGSAKLAVANLSGANLKQANLEYANLVAADLSHANLKDTKLGGANFSDANLTGVNLVGVVLNSVNLSRANLTEVNLCGSSLVSANLNGATLSSADLRGADLNGTNLEKANLKGANLSGVANLDKAKLAGAIMPDGTIHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWD8</accession>
    <name>A0A2G4EWD8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isochorismate-pyruvate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000150">
        <property type="protein sequence ID" value="PHX53839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53839">
        <property type="protein sequence ID" value="PHX53839"/>
        <property type="gene ID" value="CP500_019375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016835">
        <property type="term" value="F:carbon-oxygen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009697">
        <property type="term" value="P:salicylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008241">
        <property type="entry name" value="Isochorismate_pyruvate-lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029775">
        <property type="entry name" value="Isochor_pyr_lyas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR029775-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="97" mass="11445" checksum="E0EA2B4DAC932120" modified="2018-01-31" version="1">MKTPDECANILEVREEIDLIDREVIDALSKRFQYVLAAARFKTSENSVKAPDRFYAMLQQRREWAQEAGLSADVVEKLYRDLVNHFIEEELKHYKPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWJ4</accession>
    <name>A0A2G4EWJ4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase_S8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_018935</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000141">
        <property type="protein sequence ID" value="PHX53915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53915">
        <property type="protein sequence ID" value="PHX53915"/>
        <property type="gene ID" value="CP500_018935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07473">
        <property type="entry name" value="Peptidases_S8_Subtilisin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034204">
        <property type="entry name" value="PfSUB1-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="246"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="529" mass="54430" checksum="1CB2B1849EE387C6" modified="2018-01-31" version="1">MAGPSPDGLSYFLDNNPNSFTLTPGFLTPYQNGLFALGGNDFIVGASDASLISGGVGNDTLVGGQGDDILIGGKGADVLIGEGGKDSLTGGLGADTFVLRSDSAVTNSAAADIITDFNSSVDAIALTDNLTETDLIIEQIAIAPNTSNTLIKIRQSGAILGLVANTSPKDLTGKFISATPTTISANNISNLGSFDSRFGFGLVNAAAAVAKAKGVATFPDVPDLGGDNWGRDLIKAPEVWAQGLTGDGIVIAVIDSGIDYKHPDLTGNIWSNSGENGLDTQGRNKANNGLDDDGNGFVDDFRGWDFVNRDNDPMDDNNHGTHISGLVGAKNDGVGMTGTAPTAKIMPLKILDSTGSGRIRDEIAALNYAVANGANIINVSLGGEQLNDNELNAIRAAEAKGVIVVSAAGNDGGTQVDYPAKFANEVGIAVGSIQRNKQFADYSSRAGTEVIDYFIAPGGDGGRADSGDIYSTVPLSVPGTPYRYFAGTSMAVAQVSGVIALMLQANPNLTPAQIKRILAETANRQDIIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWM3</accession>
    <name>A0A2G4EWM3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Photosystem I reaction center subunit II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_018820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cellular thylakoid membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000139">
        <property type="protein sequence ID" value="PHX53934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53934">
        <property type="protein sequence ID" value="PHX53934"/>
        <property type="gene ID" value="CP500_018820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
        <property type="term" value="C:photosystem I reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003685">
        <property type="entry name" value="PsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036579">
        <property type="entry name" value="PsaD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31982">
        <property type="entry name" value="PTHR31982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02531">
        <property type="entry name" value="PsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64234">
        <property type="entry name" value="SSF64234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="141" mass="15551" checksum="9F3658DE69E702D2" modified="2018-01-31" version="1">MSEELTGQPPIFGGSTGGLLTKALVEEKYAITWTSAKEQVFEMPTGGAAIMRQGDNLLYLPRKEQCIALGGQQLRAKFKISNYKIYRVFPDGSNEYLHPKDGVFPEKVNEGRVANGSVPRNIGSNPNPIKVKFTGKKTYEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWN6</accession>
    <name>A0A2G4EWN6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000139">
        <property type="protein sequence ID" value="PHX53939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53939">
        <property type="protein sequence ID" value="PHX53939"/>
        <property type="gene ID" value="CP500_018845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="306" mass="34557" checksum="B7B645272A1AC60C" modified="2018-01-31" version="1" fragment="single">HFCPLTPCMCQLGVRNVGSNTFNEPLPLPKTKEGDIRRRNLAQQREDLEQEKVEMLEMFDRLNPEIPSEAEQLDDLRAKLAQVDEMLMDIDKQLSPDKTAATDFEQLEWLKLGLIASWADSEVRGRVIYLHHPPYVTEATKWNQAQTLAVRWHLREVFDGAARSIGDGLRGRAIVDLVLTGHAHCLEYLRTGDTGHADSHINWMICGGSGHSLRRQRAEGPVLQEFSSPSVDRVARSNVGEKASRPVAESLLYIGRSGEGSQKRRPYSCLRIDVLLGCPPKFRVRPLVAERFQGKWLDSAIEPFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWN8</accession>
    <name>A0A2G4EWN8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA/RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000144">
        <property type="protein sequence ID" value="PHX53888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53888">
        <property type="protein sequence ID" value="PHX53888"/>
        <property type="gene ID" value="CP500_019090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD_C_2" evidence="1">
        <location>
            <begin position="728"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="965" mass="107422" checksum="143A9D9442C3D960" modified="2018-01-31" version="1">MDKAAECRKFIATEPLGKSGETAEQRVWDAVCEAFADRDCIAYWRYPIFSSSGDFRKEPDILIVDFELGLTIIEVKAIAIDQIVAISGHRWEFQHFYTTGGNPYQQAEHQLYAMLGYCDRETALRGKVSGRAIVALPSISQQQWHEKEFNKLPSNPPIIFQNHLHEKLGQTKIGQIDRPREKLNIDILSSPKTQHTHALIELIKNTTPVLKGNQLNPEQWQLLLAVISGTPVLKPRPRRFYLSSPKTTQPENTLLSHLPNYTTRAAVLAQLHQQFSQLDLQQERIGKQIPPGPQRIRGIAGSGKTVLLCQKAALMHLKYPEWDIALVFFSRSLYEQIIALLDKWLRRFSNGEIGYDAHNNQKLRSLHAWGAQDRPGLYSTICRAAGVGRLTVGDTDFQEPSQALAYVCRHLLKSAKIPQIFDAILIDESQDLVVDEKFNFQGKQPFFWMAYQALRLVNTPPTPPDQGGANQDNQVVSLELKTLEKFSPPLQGGVGGGRDLRRLIWAYDEAQSLECLEIPTASKLFGEELGHLVSGEYTHGIKKTEIMHKCYRVPGPILTAAHGIGMGLLRRGGMLTGITRAEDWKAIGYEVVDTKSEINAPIVKNNQYQLAKKITISRPPDNSPNLVPQMWVNPVLEFEAYRSRQEELTALAEDILDNLKVDGLRPSREILVIVLGSGFEAMELETYVANFLMKQGIDIYIPSTPSCNLLKVNQADCQPDRFWCEGGVTVSRIHRAKGNEADMVYLIGFDYIAKNESNLSLRNQLFVALTRSKGWLKLSGTGAYPMYDEMWRVMQSGDSFTFTWKQHHQRNISVTDAGELAGRYAAGGRNFQGVDLAGADLAGVNLQRANLVNSKLVGADLKNANLDGARLIIADLSGADLSSASFKKAKLVGAILNDVKLNQANLSRADLSEAQLRNADLRCAILTKANLSGADLQGANLEGADLTDVRLSGTIMPDGTENLTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWU5</accession>
    <name>A0A2G4EWU5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IV pili twitching motility protein PilT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_018910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000141">
        <property type="protein sequence ID" value="PHX53910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53910">
        <property type="protein sequence ID" value="PHX53910"/>
        <property type="gene ID" value="CP500_018910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="3">
        <location>
            <begin position="243"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="423" mass="46937" checksum="2134B2CFC0D6102A" modified="2018-01-31" version="1">MNPLDNPTPVRPDAQARRTPPPPPPLAAHPASPAAPPAPAAQRQPEVPLSTIEQMVRDAHAVAASDIHIRVGQVPRFRIRGVMQLAMNHVKVTPEFFEHYLAEMFSPEQRKQFTTTKELDGAIFYPGFVRCRVNCFDSLSGGAIVLRLINLEIPTIDAMRLPEVLKNIILRSQGLILVTGPTGSGKSTTVAAMIDHLNQMEQKHVVTIEDPIEFIHPSKKCLVSQREVGLHTHEFQQALRAVLREDPDVILIGEMRDRITINTALQAAQTGHLVLGTLHTRSAINAINRLLNVYPPEEQQAMRIQICDSLVAVIAQLLLPTVDNRRVAVHDILVNTPAMHDYLMKGDDDEAFRLMEHDTYEGMQIINQALYALVLEGRVTIEEAAKASPEATDLDRRLRTGGYDAADARGFQGSKKERPVTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWV4</accession>
    <name>A0A2G4EWV4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000137">
        <property type="protein sequence ID" value="PHX53946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53946">
        <property type="protein sequence ID" value="PHX53946"/>
        <property type="gene ID" value="CP500_018745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="12"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="326" mass="35883" checksum="7294106265DD7086" modified="2018-01-31" version="1">MQTNQKLLLPTMGCGTWAWGNRFLWGYDESMDEELQAAFNLCVSNGVTLFDTGDSYGTGKLNGRSEQLLGQFSKQYEGANKESICIATKLAAYPWRLTRKSMISAGKASGSRLGKNIDLVQMHWSTANYAPWQESALLDGLGDLYEQGLVKGVGLSNYGPKRLKWAYAKFCDRQIPITTLQVQYSLLSTYPVTELGLKEVCDELGIKLIAYSPLALGLLTGKYSENGLLPKGIRGLACKQILPGMRSLLDCLREIATFRNKTVSQVAINWCICKETMPIPGAKSAAQARDNIGALGWKLDSGEIAELDKAAAKVDKKMVQNIFQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWY5</accession>
    <name>A0A2G4EWY5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase C14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000128">
        <property type="protein sequence ID" value="PHX54062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54062">
        <property type="protein sequence ID" value="PHX54062"/>
        <property type="gene ID" value="CP500_018165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011189">
        <property type="entry name" value="UCP_caspase_lke"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007398">
        <property type="entry name" value="Sll0148_caspase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="718" mass="77167" checksum="69E8CE09F1B0A0FA" modified="2018-01-31" version="1">MGLKRRNFLQQAGWVLAALGISEAGWERLGDRYLQALAQPTARKLALLVGVDQYPGSALHGCVTDVELQRELLVYRFGFQSSDILTLTDSQATRENIETAFVTHLTQQAKPGDAVVFHFSGCGSRLSLGESLTVMPNSLVPVDDRVPTLGNRVVNDILEETLLLLMRSLPTSSSIAILDTSYNYPGFEGAGNFRIRSRPRPIVASPSIGELDLLDRLKLSSNQIYTPTTILTAAAPAQFAAEVQWNGFTAGLFTYALTQTLWWTTPASSLQVSFSRAAGQVEQITGRAQQPQILNDDLQAPSGMFSTSILNLSADGAVSVVEDGGKTVQLWLAGLPPEVLECCGGSVFSSVSSEGGRLLLLRRTGLTAKAQVLIPGQLTAGDLVREEIRVLPRNMGLTVALNSDLERIERVDATSAFAILAQVSAVGGDQRADYRFGRVPERTSSQAAAGYEAGLYRGRYGLFSLGETLIPHSEGDGGEAVKLAVQRLTPQLQTLLAMKLLRLTANEGSSRLKVRAMLATLAPQAQTVAQRSPVRGTGDDRVSSRYGESEKSGSLGILSVKAGSLIQYRLYNDGDLPVYFMVFRSDSSGLLLVLNSDGETSVPRPMQTIAPGANLSLSQARAIGPEASRAIVLAETLIIFSESPFDRTLAALQGGMQQVRDALPIRVLLNPLNVARAVLEDLHAASMTGVKKVGISTDDLALDVSVWATLSFVYRVVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX81</accession>
    <name>A0A2G4EX81_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3 8">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_019790</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3 8"/>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245738">
        <property type="entry name" value="M.Tbo703ORF19790P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53757">
        <property type="protein sequence ID" value="PHX53757"/>
        <property type="gene ID" value="CP500_019790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023095">
        <property type="entry name" value="Ade_MeTrfase_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012263">
        <property type="entry name" value="M_m6A_EcoRV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000398">
        <property type="entry name" value="M_m6A_EcoRV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00571">
        <property type="entry name" value="dam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000398-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="291" mass="33759" checksum="ACDA59FD5A1DDC15" modified="2018-01-31" version="1">MSGSAPSQILPRPFLKWAGGKTRLITQYQPYFPEKFTTYYEPFLGGGSVFFYLAQHQPSLQAILTDINPELINAYCCVRDQVEELIELLKDHQSQHTKYHQEYYYWVRSHSYKTNVEKAARLIYLNKTCYNGLYRENSQGQFNVPIGRYKNPNICQADLLRSVSSMLASVQIEVRKFDRVMDFATSSKDFVYFDPPYHPISSTSNFTAYSRSNFKEAEQIRLRDVFAQLTERGVKVMLSNSYCDFINEIYTDTQAFKTDRMPELIEISASRGINSNSCKRGKVKELLITSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX94</accession>
    <name>A0A2G4EX94_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2811 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000125">
        <property type="protein sequence ID" value="PHX54098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54098">
        <property type="protein sequence ID" value="PHX54098"/>
        <property type="gene ID" value="CP500_017920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021231">
        <property type="entry name" value="DUF2811"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10929">
        <property type="entry name" value="DUF2811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9271" checksum="57F823988779B046" modified="2018-01-31" version="1">MNPAVSIFAEIPETLHDSLKTYLETHPEWDLDRVFCASLSLFLLQNADSGTPEASRSYRQAARVYLETLFQTPHDLQSSNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXM0</accession>
    <name>A0A2G4EXM0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="16">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">murB</name>
        <name evidence="18" type="ORF">CP500_019025</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 16">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the MurB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="16"/>
    <dbReference type="EMBL" id="NXIB02000142">
        <property type="protein sequence ID" value="PHX53907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53907">
        <property type="protein sequence ID" value="PHX53907"/>
        <property type="gene ID" value="CP500_019025"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00179">
        <property type="entry name" value="murB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 16" id="KW-0132">Cell division</keyword>
    <keyword evidence="11 16" id="KW-0133">Cell shape</keyword>
    <keyword evidence="15 16" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0274">FAD</keyword>
    <keyword evidence="8 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 16" id="KW-0521">NADP</keyword>
    <keyword evidence="13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12 16" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="17">
        <location>
            <begin position="42"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="16">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PHX53907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="318" mass="34562" checksum="FC53A397429291A8" modified="2018-01-31" version="1">MVTISNNSSVKDYQRVYSPISLRGIDCKINSQVSLAGMTSFRVGGPAEWYIAPRSIEALQASFAWADAEGLTVTLLGAGSNLLVSDRGLSGLVVGTRYLKQVSFNEETGQLTAGAGESIPRLAWLAAKRGWKGLEWAVGIPGTVGGCVVMNAGAHRGCIADILVNARVLSPRGKVEILTPQELGYRYRTSLLQGGERLVTEATFQLQPGFDRSQVMAETNNNFSQRRTSQPYHLPSCGSVFRNPTPKAAGWLIEQAGLKGYQIGGAQVAQRHANFILNCGSATANDIFQVIRHVQQQVQQRWSLLLEPEVRILGEFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXM2</accession>
    <name>A0A2G4EXM2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5-histidylcysteine sulfoxide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ovoA</name>
        <name evidence="2" type="ORF">CP500_017055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54279">
        <property type="protein sequence ID" value="PHX54279"/>
        <property type="gene ID" value="CP500_017055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027577">
        <property type="entry name" value="OvoA_Nterm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04344">
        <property type="entry name" value="ovoA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="192"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="450" mass="52411" checksum="E0FBE8F6E09C4169" modified="2018-01-31" version="1">MNSLKFQHPIQLNTCSREAILSYFQNAWEMEDMLMKSLVGAETFYLNPDSLRNPLIFYLGHCAAFYMNKLSWVNLLEKVLLPDYELIFGFGVDPQTPDELNAAISQIQWPEVAKVWEYRHQAYEIISEVIKNTPLNLPIHQNHPLWALMMGIEHQRIHFETSSMLIRQLPVEKVECPDGWQYAPSNNNISHNEMIEVSGGLVELGKPEDSSLYGWDCEYGYRQVKVEPFSASKYMITNAEFKEFVTAGGYEKQDYWDEESWGWKTEYHVKHPQFWIPNNGSYKYRAMFDEIELPLDWPVEVNHYEAMAYCRWKGEGIRLMSEAEWNLATYGSDANAKSIALDTINDFNLNLKFGSPSPVGILKQAESSSGLYDLRGNVWEWLNDDFNPLPGFKTHFLYENYAAPYFDSQHKMMLGGAWVTNGTEALKFYRNWFRPNFYQHAGFRIAKSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXU7</accession>
    <name>A0A2G4EXU7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54364">
        <property type="protein sequence ID" value="PHX54364"/>
        <property type="gene ID" value="CP500_016550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="685" mass="76163" checksum="58F7AC63A0169327" modified="2018-01-31" version="1">MKKLEFLLQKEGDRAWLPLETPDVEILEGRYRVVARVPHPNADIEIRVSYTSLLQVPPQRQVQSRSTRTNPEGLVVIIPYTRLKPGKWELSCLADPESKPAKPWQYGVQLEVLQAESETLEPLQPIDSTELTSSTIDSELAAAADRATPIPEPQPTKIYQFPIPQPPQPKSPYNLQIVLDRETFVTQLGRPLIISGKIDLPQTSRKNPTPIPESQTAELTKLIGSAELQIYLRDPQTSQVLAEIQQPMPEQLPPCIFGCVTYIPAESKSRLILGEAILRIGNATLSTQVFTITARLEQLLDVIEDNFGEQKYKTEPSLIDSKQAPIEPNLSFLKLVEKSLDSAPTADQTNQTLPPKLSSHQDKSVNNKLELPTFGRKLADSNREKLLSEIAKSPQTEVATQPPDVKLDSPALPSDIANSLEKVEVPAIDQKPENSPQPETAAAETQPAPTKQAFQTLNVENRFWSRLSSFVSKGESPEWLNNTSLSPTPKVAENTREEIVGVEESIPTPPPVVANESPIPEPKSNSWEAREFVIFDEPAPQAPKNLGEKKTRVVEAEVTPLTSYVLGQDEVVPMPVIEPPREIVAGKLVKVRVQLPELMPRIFVKIWVYDRQTYVILDGPRWITEFAANGLGNVQAMAELEIPYGCMEIEFEAIAVEMQTQRESDKITVHRQVLPPSGPTLPLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXV4</accession>
    <name>A0A2G4EXV4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54363">
        <property type="protein sequence ID" value="PHX54363"/>
        <property type="gene ID" value="CP500_016545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="172"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="473" mass="53269" checksum="7EF67170DF70B8B4" modified="2018-01-31" version="1">MHYQSQKQRHKNKTYKRIKAAFFYCLTFIFFWWSTANLGTVAQPIGTDGLNGQEMRKILDEGNLAEAVTRIELDWEEDYQKYFSANFGARSQTAGQIAKTLSRLAVETQKKPALIYAIPRTDQLELILILPDRAPILRSVPDAKLSNLKEVAKAFSSEITNPRKINTTSYLEPAQKLYQWMIAPLEADLQAAKIETLLFCVGEGLRTLPLAAMHDGQQFLIQKYSLARIPAFKFTDIRYKDLKNAQVLRMGASVFSETSNKQPLPAVQLELSAIAQEWPGQSLLNEDFTIVNLQSQLLQKKYRIIHLATHAEFRSGLPQNSYIQFWDTQLGLNQMRDLKWNNPPLELLVLSACKTAIGDKEAELGFAGLALQSGAKSALASLWYVSDAGTLALMTEFYHQLKVSKPKDIPIIKAEAMRQAQIAAIEGKVTIENGQLRSSRGERLLPLSIPQLDTKNLSHPYYWSAFTIIGSPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYC4</accession>
    <name>A0A2G4EYC4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54532">
        <property type="protein sequence ID" value="PHX54532"/>
        <property type="gene ID" value="CP500_015540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="92" mass="10847" checksum="9CDE1294D90E509C" modified="2018-01-31" version="1">MLYLAQDPVQATEISQELEQETEWEFAEIWADTLISPPYILMLVKEKSGIFCIHNPAQNYKVIFSSENYEAAKMWLLEDEYERLNSRISQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYG3</accession>
    <name>A0A2G4EYG3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA polymerase sigma factor, RpoD/SigA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_015365</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000091">
        <property type="protein sequence ID" value="PHX54575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54575">
        <property type="protein sequence ID" value="PHX54575"/>
        <property type="gene ID" value="CP500_015365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017848">
        <property type="entry name" value="RNA_pol_sigma_RpoD_cyanobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02997">
        <property type="entry name" value="Sig70-cyanoRpoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r1_2" evidence="5">
        <location>
            <begin position="10"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="88"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r3" evidence="6">
        <location>
            <begin position="167"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="8">
        <location>
            <begin position="255"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="319" mass="36336" checksum="08A66C96969089F8" modified="2018-01-31" version="1">MKTLKSSDTDSVRAYLRDIGRVPLLTHEQEILYGKQVQRSIALNQEKNIVAQELGRDPTAAEWAQAVGLSEAELQRTISHGDRAKRQMVEANLRLVVSVAKKYIKRNVDLLDLIQEGTIGMQRGVEKFDPTKGYRFSTYAYWWIRQAITRAIAEKGRTIRLPIHITEKLNKIKKAQRLLAQQLGRSATAAELASELDLTPKQIREYLDRARLPLSLDLRVGDNQDTELGDLLEDTGTTPEDFALQASLRTDLDHLMAELTPQQRDVLALRFGLEDGQTLTLAKIGDRLNISRERVRQIEREALTKLRKRKQDINDYLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYH9</accession>
    <name>A0A2G4EYH9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">High light inducible protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54546">
        <property type="protein sequence ID" value="PHX54546"/>
        <property type="gene ID" value="CP500_015440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="7085" checksum="C033920D8CD03ABA" modified="2018-01-31" version="1">MKAKTPASPKPSTPESPKKTEPAFGWNLYAEQINGRFAMVGFVSLLLVEFLTEQNFLTWIGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYK9</accession>
    <name>A0A2G4EYK9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">B12-binding domain-containing radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54614">
        <property type="protein sequence ID" value="PHX54614"/>
        <property type="gene ID" value="CP500_015155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025274">
        <property type="entry name" value="DUF4070"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034530">
        <property type="entry name" value="HpnP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13282">
        <property type="entry name" value="DUF4070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00303">
        <property type="entry name" value="hopanoid_C2-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="164"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="530" mass="60901" checksum="82802C31F6DFAD28" modified="2018-01-31" version="1">MRVLLVYPLFPKTFWSYEKILELVDRKVLLPPLGLVTVAAILPQEWEFKLVDRNIRQITEAEWEWAELVILSAMIVQKEDLLDIIREAKRRGKSVACGGPYPTSVPEEPQAAGIDYLILDEGEITLPMFVEAVLRGEKSGMYRSDGVKPDVTTTPVPRFDLLELDCYDSMSIQFSRGCPFQCEFCDIIVLYGRKPRTKNPQQLIAELDCLYNLGWRRGVFMVDDNFIGNKRNVKLLLTDLKIWQEEHKFPFTFNTEASIDLAQDQELMEMMVACNFNAVFLGIETPDEESLQMTKKFQNTRNSLIESVELIAKTGLRVMAGFIIGFDGEKAGAGQRIVDFAEAAAIPSTTFGMLQALPHTALSHRLAKEGRLREKSGNLNQTTLMNFIPTRPLEDIAREYVEAFCQVYDAEKYLDRTYRHFLMLGAPTAKIPAQFPSLIELRALLTVVWRQGFKRSTRWKFWHHLFSILKRNPAVWDHYLTVCAHNEHFLEYRQIVRDEIEAQLAEFLANESQTVYQEPVAAEEKEVQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYM7</accession>
    <name>A0A2G4EYM7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000088">
        <property type="protein sequence ID" value="PHX54623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54623">
        <property type="protein sequence ID" value="PHX54623"/>
        <property type="gene ID" value="CP500_015205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="303"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="51756" checksum="0095B6350C90C0EF" modified="2018-01-31" version="1">MSKENWLIYPTVDLFVYDLADGIGQNEEKISQNRAQFWQKIYGDKISAPQLEKLKQAETETAEYIELLGDTKLAAFESPLDGYAYPVKIGDTYAAQFDLSGKIESDKQKTFEPKEIDCLEWLKQQVISRVNPPATIGQSLLVWGQLTANDQDVLETAKNCYSKLNLFPNAKWDRDLKSTNKFLNADFYELWLPPGDRGNISQNYHVLICLFSYNGGQSIADISKTVAKLYVHLMRLFAFRNKVIWAYTQSRQLKADLKDAARTIQQIVTQLPNQVNAPKVDLKELQQSLVNSLTIFSVYANYISRLEEQENTIKTNLKNYKRRLETIGKEMENDAEAFKFLASFSDFAKEKYVWQVAADNRSLTAGLRLLENAIQTIEGIIEIERAKSDRTLNVTIGAVGVGIGTSGVYASVYASQIRSPASPTNPIDVNVVFGWSMGLGIFAGALSAMFLIIIGKKWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYN2</accession>
    <name>A0A2G4EYN2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000090">
        <property type="protein sequence ID" value="PHX54578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54578">
        <property type="protein sequence ID" value="PHX54578"/>
        <property type="gene ID" value="CP500_015305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="263"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="397" mass="45655" checksum="70D39339ADDD7C11" modified="2018-01-31" version="1">MNDREKNFTQNNRQNRGLLGAGWRPLYRQLDLEYLLHLASNDPVELAQKTLDAASDLADAMGRHQYSWWANILNVFSENTRYEIDEFWDYITPQQVYPDYRYKDTLTTETPVVQLVSRAGIPIDYVLNKLQEITIFKILDLLGKPDAITQLFMERNFDYPPERFISWERLEVLGTVYAYWAEECCWLQIDSYDRGRRRYTLICKNIAPMVSKATYNLAVILSGYKSRVGQVNSQYPIRTFPADVQSFTDTVQQAILDQNQLAVLVSGVPGTGKTAWTQAVAKEILVPLGYVIFILDHDAVENFVPPSYLERICIIINEADNLAQDRSTISAQRSNKTEHILSLLDGTLYQSVIDADGIQFQQKLVVLMTCNTTERLDSAMLRKGRVDFISEFTHKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYN3</accession>
    <name>A0A2G4EYN3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycerate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54590">
        <property type="protein sequence ID" value="PHX54590"/>
        <property type="gene ID" value="CP500_015235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="355" mass="40447" checksum="6377209FC564EA38" modified="2018-01-31" version="1">MTLMLVEILEGWISGNCPTDRDFEQLALWELADDLRSPAFGVTPTNVADVVHRKTELFFSILNILHTFPVKSTNFLEILWYLWLPLAMKLSSETQSLKRPLIQGILGGQGTGKTTLSEVLRLILAKLGYSIVNLSLDDLYLSYADRLQLQKQDPRLIWRGPPGTHDIELGIAVLDELRSSKTGELVAGKNIKIPRFDKSAWGGAGDRILPESVSDVDIVLFEGWFVGVEPVDELQLNQFLADSPFPICTESDRQFARDMNAKLWDYVPLWNRLDRLIVLYPQDYRVSQVWRNQAEQKMMAAGKSGMSELEINRFVEYFWKALHPELFIKSMVAGGVRVDLAIELKCDRTIEKIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYQ4</accession>
    <name>A0A2G4EYQ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-alanyl-D-alanine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_015000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54643">
        <property type="protein sequence ID" value="PHX54643"/>
        <property type="gene ID" value="CP500_015000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003709">
        <property type="entry name" value="Pept_M15B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02557">
        <property type="entry name" value="VanY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="VanY" evidence="3">
        <location>
            <begin position="129"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="273" mass="29796" checksum="FC5218B422737CC1" modified="2018-01-31" version="1">MDNASLSRKPPQASELAIDEIPEAVRDHSYLEVKPSQSKKKGLIWKLLALGVLAFGVSIGLHLNFNFFPDTSRAEQSQPNPVSASSPSPTSPVANSKSSTATPDKLLGHLPYQEAPASDLVAVTGDGGIKLRKAAAAKYQEMANAAAVQGIYFAPISGFRSLEDQQHVFFDVKAERKQDVSKRAEVSAPPGYSEHHTGYAIDLGDGSVPSANLSTSFEDTPAFKWLEANATSFSFELSFPKNNRQKVSYEPWHWRFVGDKQSLETFYKAHSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ39</accession>
    <name>A0A2G4EZ39_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54782">
        <property type="protein sequence ID" value="PHX54782"/>
        <property type="gene ID" value="CP500_014265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7573" checksum="4461416258698295" modified="2018-01-31" version="1">MQELRTPTKETGFLTESVDCKDGKIWIQRDRTEAGIGNELVAAGVPKEDIVLAFKAPYVRQFTEFAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ77</accession>
    <name>A0A2G4EZ77_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4278 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54824">
        <property type="protein sequence ID" value="PHX54824"/>
        <property type="gene ID" value="CP500_013930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025458">
        <property type="entry name" value="DUF4278"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14105">
        <property type="entry name" value="DUF4278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="15172" checksum="8F7349A71A0C350B" modified="2018-01-31" version="1">MKLTYRGANYEYDIPTVDMKEGEVAGKYRGQNWNYRYPRHIPVPQHAQNLQCRSVLDSTDGKSPKIDEDVATRADSARNRAIATVASSGKFEEVATVHRVNICNILDRRKQVARAKGDLKLMCLLEVESKEMAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ90</accession>
    <name>A0A2G4EZ90_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PEP-CTERM sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54833">
        <property type="protein sequence ID" value="PHX54833"/>
        <property type="gene ID" value="CP500_013980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026374">
        <property type="entry name" value="Cyano_PEP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04155">
        <property type="entry name" value="cyano_PEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="275" mass="29216" checksum="2F651BA4E3A6471F" modified="2018-01-31" version="1">MKINHGIGSIAVLFATPLVTGLSVGIAPSSAAIIAGSAAEVSIDNFSHRPTDTGTFTNTYTQAIANKGAVISAANANAVFLSNCQQLLAANLSESTVKGEGSKYSGLAQSQAAIIGDFDLDAKETFSFTFQTFLRLLTSVDNPQSERVSAQGNLSFLLIDTVSNILLDSFQLGGSLHSFKRGDLSLSYSDSFNPTQINLDFLAQGNTKESVVYSSGVYARTFDNATNLRLVEVKNNLVLAESQPVREAEPVPEPTTILGTAMFFGFLAKGRKLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZA7</accession>
    <name>A0A2G4EZA7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54844">
        <property type="protein sequence ID" value="PHX54844"/>
        <property type="gene ID" value="CP500_014035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="157" mass="18368" checksum="E7B3C6AC5D8DFE3D" modified="2018-01-31" version="1">MYTGNVTINGINQGIASRKIGKDDFYKFYKNISLSPTQLQEYIEKAFELRITIIGKKVFAVKIDSQANEETKIDWRLHTQMNPHSIFELPVKIEKFCIEFLEEQKLLYGAMDFIVTPNNEYVFLENNPFGQYLWLEIETKIPLTEEICNLLISYLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZG8</accession>
    <name>A0A2G4EZG8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_013770</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54899">
        <property type="protein sequence ID" value="PHX54899"/>
        <property type="gene ID" value="CP500_013770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="13">
        <location>
            <begin position="3"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="11">
        <location>
            <begin position="182"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="12">
        <location>
            <begin position="301"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX54899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="404" mass="46018" checksum="84206777DEA8C4BE" modified="2018-01-31" version="1">MYAIKLELKLNNKQRTLMARHSGYARFCYNYALSLYQEVKSLPGSSSKKVAAIERVFTNHVKKIPEYQWTNTLSSRVYKMTFRHFNEALSRFFKGLGEFPKFKRKKDGDSFTVDAADWNHSILLAAKKSIKIPTLGTFRLKEAIPFPCVAQTFTISRTADKWYVSFAIKADKIPPLCHPVAEPVGIDLGVSTFATLSDGNSYSSPRPLQKAKTKLSKEQWRNRKKQLGNRKLGVKASKNAHKHYRKVAKIHGRTANVRRDFLQKTTTDISQKYAHIRIEDLKVSGLMANQKLAAAISDCGFYEFRRQLTYKSGMYGTKVELVDRWFPSSKTCSNCGHVQSMPLKERVFNCGYCNLSINRDVNAAINLSRCSEKVRLAQSEVKPVDKKEPTPLVEAGSEHQICRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZH4</accession>
    <name>A0A2G4EZH4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Biotin carboxylase</fullName>
            <ecNumber evidence="3 9">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">accC</name>
        <name evidence="12" type="ORF">CP500_013520</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="3 9"/>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54903">
        <property type="protein sequence ID" value="PHX54903"/>
        <property type="gene ID" value="CP500_013520"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0092">Biotin</keyword>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="11">
        <location>
            <begin position="2"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="121"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX54903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="451" mass="49479" checksum="6BC97DF43BEA29E4" modified="2018-01-31" version="1">MGFSKILIANRGEIALRILRTCEEMGIATVAVHSTVDKHALHVQLADEAVCIGPPTSSKSYLNIPNIIAAALTRNASAIHPGYGFLAENARFAEICADHQITFIGPTPAAMRAMGDKSTAKETMQRVKVPTVPGSEGLLADDREALSIAREIGYPVMIKATAGGGGRGMRLVREASELPKLFSAAQGEADAAFGNPGLYLEKFIERPRHIEIQILADNYGNVIHLGERDCSIQRRHQKLLEEAPSPALSQKLRDQMGHAAIAAAKSINYTGAGTVEFLLDKSGKFYFMEMNTRIQVEHTVTEMITGLDLIAEQIRIAQGEKLQIKQNQVILSGHAIECRINAEDPDRNFRPHPGIITGFLPPGGPGVRMDSHVYTDYEIPAYYDSLIGKLIVWGRDRPSAIRRMKRALRECAITGVPTTLSFHQKILDSPEFLSGEVYTNFVEQFMGQHGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZZ0</accession>
    <name>A0A2G4EZZ0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">General secretion pathway protein GspH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55076">
        <property type="protein sequence ID" value="PHX55076"/>
        <property type="gene ID" value="CP500_012700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031975">
        <property type="entry name" value="Pilin_GH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16734">
        <property type="entry name" value="Pilin_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="18044" checksum="7D6437B5CE08FB3A" modified="2018-01-31" version="1">MSQQDSKSASISPNGCGCLLLLMGIGVIGAAIALPPLLNSTNPNKKSEAKHYVASMNKGQQAYFEESSVFGTSIEAFGLGLKTETTNFKYSVSTSKKAAFNYGVSKQPQLKSYVGGVFRVPAKEVEPNAAKDKMTTASILCEADSPGTIKPPEPTNQNGKIACGTGTTEVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F024</accession>
    <name>A0A2G4F024_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="5">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_012590</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55106">
        <property type="protein sequence ID" value="PHX55106"/>
        <property type="gene ID" value="CP500_012590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="PTHR23151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="8">
        <location>
            <begin position="127"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="430" mass="45119" checksum="ECED5487D509472D" modified="2018-01-31" version="1">MIREVFMPALSSTMTEGKIVSWVKSAGDKVEKGETVVVVESDKADMDVESFYEGYLAIIMVPAGEVAPVGAAIALVAETEAEIAEAQKQGTAAPAAAAPVAAAPPVAATTSSPGLQQNVSRQNGRSVVSPRARKLAKELKVDLNAIKGSGPHGRIVAEDVEAAAGKAQPAVVQQLVTVPAALAPAAPAPAPAAAKPAPQAVPAMAMTGQTVPMNALQNAVVRNMAVSLTVPCFRVGYTITTDNLDKLYKQIKSKGVTMTALLSKAVAVTLQKHPLLNACYVESAIQYRADINVAVAVAMEGGGLITPVLQNADRLDIYSLSRTWKDLVDRARTKQLKPDEYSTGTFTLSNLGMFGVDKFDAILPPNQGSILAIGSSRPQVVANEEGLMGVKRQMQVNITCDHRVIYGADAASFLQDLAKLIETNPQSLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F029</accession>
    <name>A0A2G4F029_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Asparagine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_014105</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54797">
        <property type="protein sequence ID" value="PHX54797"/>
        <property type="gene ID" value="CP500_014105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="6">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="5">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="557" mass="62541" checksum="74EF846E13BAF11E" modified="2018-01-31" version="1">MQNQKSINPNWTIAWGPAARSHAVTWETPGFAIIGAEPTFSPTQRFVLVGDCSFDRTLLLKQQTDTDGLTDLAIVGKLWETSGTETLSLLEGQFALAVWDREEKTLCLGRDRVGAKTLYYTRTGTTRWIAPRLRSLNPYHDRTLDLVALRDYLCCAFVPGSQTLWEAVRELRPGSFLYLPDVKAQRYWQPQEQIANADRPLAWHSQRVRSLLEQLVQEALPAGEPVAAYLSGGIDSSCVTAIAARLHDRPVHTFSMHFGAQYPSEIEFANIVAAHCGTEHHILEVSPKQIWELLPETLAAMDDPVGEGLTVPNLLLGRSAKQFADVVLNGEGGDPCFGGPKNKPMLLNSLYGSIQGKPDAIAAYLTSFQKCYVDLPRLLKPEVWNQVKDAPSVFAEELEQTETTFLNRLMRLNIEYKGADYILTKVNNLTAAAGLKARSPLFDARMVALSLQIPPEYKLSGAQEKAVLKAAVADLLPDVIINRPKSGMVMSMQQWFLRDWQRQARSLLLNRRAAIAPYLDRALIDEWLNYRGEVFPRYGLKLWLLVTLEIWLQVNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F067</accession>
    <name>A0A2G4F067_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATPase_AAA_core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55143">
        <property type="protein sequence ID" value="PHX55143"/>
        <property type="gene ID" value="CP500_012220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="30"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="380" mass="42967" checksum="AE920C9835C84E2F" modified="2018-01-31" version="1">MTPHSRITSIKIQGYRPFRDFTAPLEPLEIIVGANGSGKSSLFEFLKFLTDSMESEIPNEIIKGSIGQQIFHLPGSEKFEWELKIDTGESNISYQGELMGPRSNPQISFERVESSQHLFMDIKGTEGLYREPGYAETNRVFPKRNQLALRTITNPGLATLYKLREYIGEWKFYSSFNIANHKIRKSVLIEQEPVLDEDAGNLSSVLHYLMTEHSAVFDDLQQHLQSVIPGFKKMTVKARGGPGEVIAFWQEKGINQDLSLADLSDGILRLICWICLCLHPKPPSLICIDEPDQGVHPRTLPLLAGLFEKAAERTQVLLATHSSYFLTQFDISQIAVMRKENGESKFIKPGNSKVLTDMLDDFGTEEIEKLHRSDELELLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F076</accession>
    <name>A0A2G4F076_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55160">
        <property type="protein sequence ID" value="PHX55160"/>
        <property type="gene ID" value="CP500_012315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="196" mass="22756" checksum="DF0C01D04F10AD8C" modified="2018-01-31" version="1">MIAISQTPQKMSVEEYLEWEAQQEIRHEYVNGEVFAMTGSTIPHNDLALNFYRNLYPHLRSRGCRMNVSDVKLQVSFQSRYYYPDVIVSCDPQDLNSRKFIQNPKIIVEVLSPSTSAKDRDEKFTCYLKIPTLQEYILIDAEKIFVERYSRGEGRMWLYYSYTAGEIISLSSIGFDLPIALLYEGVQFETETATEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0D6</accession>
    <name>A0A2G4F0D6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55220">
        <property type="protein sequence ID" value="PHX55220"/>
        <property type="gene ID" value="CP500_011995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="26600" checksum="11014E205531C565" modified="2018-01-31" version="1">MSENDEIAVSKTLIAEQQAMWDAKAKVRVLLNLWNEGEGKNKVNQGKLTKLIARTNETKKTYEGVLKELEESGAIAYFREKGRSQVELTAKGKEVLAAGLKSADSVFEFDGAQMGARLGNALLKWMRHEDAAVGVGVEKGKGDVGAIASYEEFMSVALKVYDSLNRDYNLDDLVPIYRMRRAIGERVGRSQFNEWLLEMQANDIFQLIGGSVEDSAPDKIEDSITTKVNGLRCYVKRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0G0</accession>
    <name>A0A2G4F0G0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55228">
        <property type="protein sequence ID" value="PHX55228"/>
        <property type="gene ID" value="CP500_011860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="PTHR19353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="2">
        <location>
            <begin position="51"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="317" mass="37066" checksum="384624CD5E797819" modified="2018-01-31" version="1">MKREYQQYKFSLEIKIQLKELTKLDNWHGLLALLQDCTLILASILITSYVTWFFYPIALLVIGSRQRALTTLLHDSAHGVLAKNKLLNSFLGTFGSGYLIFQQMIPYKKSHCYEHHSHLGNPEVDPDFKFYLKEGLYCEQSPKEFLVNHIIKPLLLFKVPQYIFYLINNRLFGKGCNLYETLIMLTYVFTIVSASVWFGFLDELILFWLVPYVTVFQVLGYFIEVSEHYPLVGKNTVDLYMTRNRFSPWYEAFFTSIHGENFHLVHHLMPSLPFWNLAQAHKILLVDPNYFRHNSLTGGIFFPSNGFSSIVSTFIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0H7</accession>
    <name>A0A2G4F0H7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55260">
        <property type="protein sequence ID" value="PHX55260"/>
        <property type="gene ID" value="CP500_011810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17409" checksum="3C7B12A68C877536" modified="2018-01-31" version="1">MVNTYFLDTSALVKRYVPETGSNWIQSITDGAANNDLTISQITWVELHSALSRRQREGSMSAGELDIILQKFRNEFDTWYRIIEVDQALIENAGQLVVQYPLRAYDAVQLASGLYVKSLLLSQPETRLVFVSADNRLLNIAQSAGLAIDNPNNYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0H9</accession>
    <name>A0A2G4F0H9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_011545</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55274">
        <property type="protein sequence ID" value="PHX55274"/>
        <property type="gene ID" value="CP500_011545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="34"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="428"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="470"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="512"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="554"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="637"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="678"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="713" mass="78421" checksum="D438DB534EDFF33A" modified="2018-01-31" version="1">MSYCINSHCQNTQNLDRATVCKSCGSNLLLKNRYRVFHTLGQNLADRTFLAVDEDQPSAPRCVIQQFCQPEIVADGQKQLNRTFSASAKVLDELGKHPQIPKLLASFEFDGCQYLVQEYIDGRNLASQLSEKGVFNEIHIWYLLNQLLPVLQFVHDNQLIHRDIKPSNIIHRKSPQASSALVGKEYLHPWDDESGLVLVDFAAAIPANSGPLKTDMVTGSAEYAAPEQIKGQAIPSSDIYSLGVTCIHLLTGMSPFDLFDLKADTWAWRDYLKAPVSTRLGRILDQMVHRETSKRYPTASAILKDMKHGPAPLDIVLGKPQWTLGVWAGAVVALISLVLGSRFQSPQPQAFTYQEPAAIPEIKFNPPPMQDFQGQESIAPTAVRTLATLDKNPVWAVAVTPNGVIVSGNNDGTIQLLNKDSGKVLKTLRGHSAPVWSVAVSPDRTTIASGSADRTIKLWNLYTGQLIRSWDAHTNGVFSVAFSPDGSTIASVGKDKTLKLWQVDDGVELETFKQLADEVDSVVFSPDEETLATGNSDGTIKLWNWQTGELKQTFIGHSEEVTSLAISPDGKTLASGSWDKIVKLWDLSANHESQQLRESQLPTFSSNDDRIEYPDLNLEINTNNESQQPSGSLLRTLIDHSDPIQSLAFSPDGNKLASSDLSGTIKLWEVSSGEITGTLKEHSTLVKLAFNPQDQTLVSGSFDDTIKVWQVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0K8</accession>
    <name>A0A2G4F0K8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55292">
        <property type="protein sequence ID" value="PHX55292"/>
        <property type="gene ID" value="CP500_011640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022623">
        <property type="entry name" value="Glyco_trans_4_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12000">
        <property type="entry name" value="Glyco_trans_4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4_3" evidence="2">
        <location>
            <begin position="26"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="213"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="426" mass="48224" checksum="CB621B8B4B846255" modified="2018-01-31" version="1">MKALFLHPNFPAQYRHIITALGADPKNQVVFGTKNERPEWNIPGVRKAAFTPSREPNAQTHQYVRPLESAVIYGQAVFRMAEQLKADGFVPDIICGHSGWGPTLFVKEAFPNTPLLCYFEWFYHAIGSDADFDPAEPLTVDDMARIRIKNAPILIDLYSCDWGLSPTYWQRSQFPPELQQKLSVLHDGVDTDYFKPNPGAKLILPNLDLSGVDEIVTYVSRGMEPYRGFPEFIESIAYVQERRPNCHVVIVGSERVCYGRSLPNGESYKDYMLKKIPLDLSRVHFVGPLPYGLYLKVIQASDVHVYLTRPFVLSWSMIESLSTGCLVIGSDTGPVREVIRDGENGLLVDYFSPKQVADRIDEVLDHPTRMAEIRVKARETALERYSLAKMLPQHLRLIEQVANRSMPPTVGMEPERELAASFAVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0U7</accession>
    <name>A0A2G4F0U7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_010945</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55383">
        <property type="protein sequence ID" value="PHX55383"/>
        <property type="gene ID" value="CP500_010945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022346">
        <property type="entry name" value="T2SS_GspH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12019">
        <property type="entry name" value="GspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="GspH" evidence="11">
        <location>
            <begin position="71"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX55383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="211" mass="22807" checksum="A01E647D360D76C0" modified="2018-01-31" version="1">MKTPILLKILQSCHAKATPNFPKTRSRKGDQGFTLLEVLVTVLVLGILSSIAAPSWLAFINNQRVRTVNDRVLQSLRSAQSEAKRTKRDVTVTFYTSSSTPSVDPPRVEIDTNPAETDTSKKEIRKETFSSGGEIKPGTIALTVNQPAASTPANSITFDYQGNLPTNTTPFYVTVAPASGGQKKCVIVQTILGAMTTDEGTFDTNTKQGCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0X0</accession>
    <name>A0A2G4F0X0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55401">
        <property type="protein sequence ID" value="PHX55401"/>
        <property type="gene ID" value="CP500_011040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="11612" checksum="D0C7B05981C4107B" modified="2018-01-31" version="1">MNEIVEKAQQAIATPEVQEMLKKLSEYGLGVFMPHMHDPETGDFAPLPSGIVAVEDNLQVSFHHASEPEVSNARPVGWVWDNSSQTAMACTTCMEYSGRHSKTNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F118</accession>
    <name>A0A2G4F118_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55474">
        <property type="protein sequence ID" value="PHX55474"/>
        <property type="gene ID" value="CP500_010645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="12319" checksum="F3D70E5D6334645E" modified="2018-01-31" version="1">MGKKSKVKKSCLLSQRLQEALDRGSKVWMKTNNSSFGGIPINLSGEFAEILVIVPPSEHGENNDSYGQVSWLIRLSDIIAVAYPTEYWSKDRLESLLKPDAVTSEMGDYPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F157</accession>
    <name>A0A2G4F157_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TIGR04168 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55485">
        <property type="protein sequence ID" value="PHX55485"/>
        <property type="gene ID" value="CP500_010630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07397">
        <property type="entry name" value="MPP_NostocDevT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027629">
        <property type="entry name" value="DevT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35769">
        <property type="entry name" value="PTHR35769"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04168">
        <property type="entry name" value="TIGR04168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="7"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="304" mass="33737" checksum="32FF4390A58D44CD" modified="2018-01-31" version="1">MNQTKSIKIAVVGDVHDLWEPEDGEALKHLGADLVLFVGDFGNESVEVVRAIAQLDIPKAAVFGNHDAWYTATDWGRSKCPYDRQLENRVKQQIDLMGEAHVGYSKRDFPELGVTVVGSRPFTWGGSDWKYNDFYSEWFGVESFAESARLIAGAAADADCENVIFLGHTGPKGLGEAPGDLCGRDWKPLGGDWGDPDFAEAIDKTRNSGKHIPLVTFGHMHHQLRHVKHEFRKSVVSAEGTVYLNAASVPRIVERECSKLRNFSIVRLETGVVSEVSQVWVGEDFAVEREQILYRQTESATACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F197</accession>
    <name>A0A2G4F197_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55237">
        <property type="protein sequence ID" value="PHX55237"/>
        <property type="gene ID" value="CP500_011910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="251" mass="28222" checksum="5B1311793F837DCD" modified="2018-01-31" version="1">MQKVDFEIQLPETEIVRNLPIQEEFFWLSQNGNQGKLRLHDYAQIYRIPHLYEYLMEKLQAKSHIVLSSLLIDRVTQAGDDVKDLIVLEVGAGSGMLGQALADLGVKSITGIDILPEAAQAAKRECPGVYENYYVEDLTNLSSTARNALSSRGFNCMVCASALTSNHIPPLALATAFNLIAPNGSIAFNVQKKHWEEKGEASFVAWHPWVAETDIFEIAQMHDYQHRFHMDGRPLYYKAMIGTKRANIQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F198</accession>
    <name>A0A2G4F198_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55525">
        <property type="protein sequence ID" value="PHX55525"/>
        <property type="gene ID" value="CP500_010495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="19881" checksum="1F9EEE97A66AD932" modified="2018-01-31" version="1">MTLTVTYDSNGGQNWRGTDDIDVIDCGSGFDLVFAGGGDDIVTANRGSDVIDGGDGSDTLRGGRGQDFLIGGNGDDFLCGDFGTDTLMGGNGADMFVFRPETATPLANLAYADIVLDFNAAQGDKIGLTAGIAIAEIALQVIDTDANGQADATLVKFSANNGDRILAVVLGTVNAAGQTTLSNADFITLPNNIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1A5</accession>
    <name>A0A2G4F1A5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1816 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55518">
        <property type="protein sequence ID" value="PHX55518"/>
        <property type="gene ID" value="CP500_010450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014945">
        <property type="entry name" value="DUF1816"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08846">
        <property type="entry name" value="DUF1816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="90" mass="10311" checksum="619B0DE303C545ED" modified="2018-01-31" version="1">MFGFSILAMYVIAFLILTQPMGSGQSRQWWVELDTDSPNRTYYFGPYRSKDEADNSTIGYIKDLEKKGAKKISINIQQGRQPTQLKANQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1C0</accession>
    <name>A0A2G4F1C0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cobA</name>
        <name evidence="8" type="ORF">CP500_010270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55560">
        <property type="protein sequence ID" value="PHX55560"/>
        <property type="gene ID" value="CP500_010270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="276" mass="29603" checksum="318DFA5F446D8C71" modified="2018-01-31" version="1">MNRKDTQEAKAQAEKEVKMSVGKVYLVGAGPGDPGLMTLKGKTLLECADVVIYDALVSPQILESINPQAERIDAGKRRGRHSLIQDETTQLLIEKAQDNAIVVRLKGGDPFIFGRGGEEMEDLVKAGVSVEVVPGVTSGIAAAAYAGIPLTHRSYSSSVTFVTGHESAGKYRPEVNWQAIAHGSETIVIYMGIHNLPYIIGQLTAAELSVETPIALVRWGTRPEQEELIGTLATIVEQVEVTGFAAPAIAVIGNVVNLHGILSGCRPVYQNNDPYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1H0</accession>
    <name>A0A2G4F1H0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">M23 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_010040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55610">
        <property type="protein sequence ID" value="PHX55610"/>
        <property type="gene ID" value="CP500_010040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M23" evidence="1">
        <location>
            <begin position="80"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="22647" checksum="8D93A97103D8FCF5" modified="2018-01-31" version="1">MQDSRGPLTVKRFFRLRQMLLLALSIAIVLISPYLQQELVKAQSGLPSKVATGNLWQEASFPVEKFQDYTSPFGPRGGDFHYGLDMAAPEGSYIRNWWGGQVVEVWEDGRCGTGMVVRSGDWEHIYCHLRGRVETANGGRYYTDREGLQIWQGQTVPAGARIARVGMTGRTSGPHLHWGLKYSGRWVDPALVLREMYAQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1I7</accession>
    <name>A0A2G4F1I7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Photosystem reaction center subunit H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55631">
        <property type="protein sequence ID" value="PHX55631"/>
        <property type="gene ID" value="CP500_009885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="2">
        <location>
            <begin position="9"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="PRC" evidence="2">
        <location>
            <begin position="89"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="335" mass="38129" checksum="3D88D83EE8FD79AF" modified="2018-01-31" version="1">MTSEQICQRSDLLGTQVITRDRGKRLGVVSQLWVDIDRREVVAIGLRDNIFAVAGMPRFLFLSSVSEIGDVVLVEDESAIEDDVDVEVYSILINSEVITETGEPLGRVRGFRFDPEDGKLVSIIIASLGIPQIPEQVLSTYDLGIEEIVSSGPNRLIVFEGSEERLRQLSVGLLERVGLGQAPWERDEEEQSYYPKPVGTPNQLGPGVPLAAPEMRRKSAPVAEEVPWDEDSPWKRAPVRQPMRQVQPTPVADYEDEYEEDNWGGDEDDYEEEYEEKGYDRPESYRKEPVVEYEYEDDVEADAWADDESPKPYKAPRVNIPEKTKTREYEKEPEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1M2</accession>
    <name>A0A2G4F1M2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF86 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_011250</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the HepT RNase toxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55367">
        <property type="protein sequence ID" value="PHX55367"/>
        <property type="gene ID" value="CP500_011250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008201">
        <property type="entry name" value="HepT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037038">
        <property type="entry name" value="HepT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01934">
        <property type="entry name" value="DUF86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="142" mass="16398" checksum="5C57F696FE99D3E4" modified="2018-01-31" version="1">MSIQKTVVLTRLKFIGDYLLELRRFESMSLENYLVSFDSKIISERIIELIVQAAVDINDHILTRGMKVSSDSNRESFVQLGSYGIITPEVTEELAKSAGLRNILAHRYLEIDYVILFNSVQIALIYYPIYIEQVAEYISREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F246</accession>
    <name>A0A2G4F246_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4926 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55844">
        <property type="protein sequence ID" value="PHX55844"/>
        <property type="gene ID" value="CP500_008675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032568">
        <property type="entry name" value="DUF4926"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16277">
        <property type="entry name" value="DUF4926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9198" checksum="5720D1C052110A3F" modified="2018-01-31" version="1">MKLLDVVALLENLPELGLYRGQVGTVVDEYDAEFVEVEFSDLQGRTYALEALSQSQLMILYHSPIAETRWLKTQPSLQKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F270</accession>
    <name>A0A2G4F270_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_008485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55860">
        <property type="protein sequence ID" value="PHX55860"/>
        <property type="gene ID" value="CP500_008485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="92" mass="10116" checksum="05718CBF1ACFCCED" modified="2018-01-31" version="1">MSENEEVTPSDRDESAEDSTENSTLTDAEELVEVIAEFERYRERLVTETIAAAQKAKLPQKPALAKIEPELAKIDAGLESLRAQLAAITTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2A0</accession>
    <name>A0A2G4F2A0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14">Cytochrome b559 subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 15">PSII reaction center subunit V</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">psbE</name>
        <name evidence="18" type="ORF">CP500_009985</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 15">This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="13">With its partner (PsbF) binds heme. PSII binds additional chlorophylls, carotenoids and specific lipids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha subunit and a beta subunit. Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Heterodimer of an alpha subunit and beta subunit. Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13 15">Cellular thylakoid membrane</location>
            <topology evidence="13 15">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13 15">Belongs to the PsbE/PsbF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55597">
        <property type="protein sequence ID" value="PHX55597"/>
        <property type="gene ID" value="CP500_009985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00642">
        <property type="entry name" value="PSII_PsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006217">
        <property type="entry name" value="PSII_cyt_b559_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037025">
        <property type="entry name" value="PSII_cyt_b559_asu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006216">
        <property type="entry name" value="PSII_cyt_b559_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013081">
        <property type="entry name" value="PSII_cyt_b559_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013082">
        <property type="entry name" value="PSII_cytb559_asu_lum"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00283">
        <property type="entry name" value="Cytochrom_B559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00284">
        <property type="entry name" value="Cytochrom_B559a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000036">
        <property type="entry name" value="PsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01332">
        <property type="entry name" value="cyt_b559_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00537">
        <property type="entry name" value="CYTOCHROME_B559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 13 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 15" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13 15" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="12 13 15" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="6 13 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_B559" evidence="16">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_B559a" evidence="17">
        <location>
            <begin position="42"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared with beta subunit</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PHX55597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9280" checksum="E959AEEA44E281D3" modified="2018-01-31" version="1">MAGTTGERPFGDIITSIRYWVIHSITIPALFIAGWLFVSTGLAYDAFGTPRPNQYFTPQREEVPIISDRFEAKKQVDQFIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2B5</accession>
    <name>A0A2G4F2B5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55886">
        <property type="protein sequence ID" value="PHX55886"/>
        <property type="gene ID" value="CP500_008295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="91" mass="9934" checksum="20F45B3C1A37BF2E" modified="2018-01-31" version="1">MSTITDIGTLISRNPDIHGGCPIIAGSGVRVRRIAIWYKQGLIAEEIADRIGNLTLTQVYAALTYYHANREEIDADIAAEETEGDRSSSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2K0</accession>
    <name>A0A2G4F2K0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55991">
        <property type="protein sequence ID" value="PHX55991"/>
        <property type="gene ID" value="CP500_007845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14708" checksum="14AA7193EEC7565C" modified="2018-01-31" version="1">MPKPAILCVDDEISVLESLEIELQRAFNGIYLCEFAESAAEALEIIDELCEDEVNILVIVSDWLMPGMKGDELLIKIHQRYPKIVTVMLTGQADQAAIERTKTQANLHAFLQKPWKNDELIEAIKSGLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2S1</accession>
    <name>A0A2G4F2S1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Adaptive-response sensory-kinase SasA</fullName>
            <ecNumber evidence="3">2.7.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Synechococcus adaptive sensor protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sasA</name>
        <name evidence="5" type="ORF">CP500_007130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with KaiC. Participates in the KaiABC complex, whose core is composed of a KaiC homohexamer, a KaiB dimer and two KaiA dimers.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56074">
        <property type="protein sequence ID" value="PHX56074"/>
        <property type="gene ID" value="CP500_007130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02978">
        <property type="entry name" value="KaiB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01837">
        <property type="entry name" value="Kinase_SasA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011649">
        <property type="entry name" value="KaiB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023527">
        <property type="entry name" value="Kinase_SasA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07689">
        <property type="entry name" value="KaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01248">
        <property type="entry name" value="KaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0090">Biological rhythms</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="186"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine; by autocatalysis" evidence="3">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="411" mass="46306" checksum="4278C4A19319018C" modified="2018-01-31" version="1">MVNCFHPIDKLNNVNQTHGQDTDCSPEQPATSQSVLQLLLFVDKRPSSREQTRHIRQSLKDLKAEWDFELQIIDVGEQPDLAEHFKVVATPSLLKIHPDPRQTLAGSNLSAQLEHWWPRWQLSVEEYAAQQQSATPLAETLADPKPIYSVACAVELVQLADEVFRLKQEKEHLEEQLQLKDRIIAMLAHDLRNPLTAASLALETLESNQKVKDGETPRLTPTLAAHLMKQARRQIRIVDRMITDILQAARGTKAQLHMAPKKIQLGTICQDVLLQFQDKFQAKSLKLETDIPTDLPLVYADPDRIKQVIANLLDNASKYTPEQGTVSISLLHRTAYKVQVSIGNSGPGIPEENCESIFEDSFRLQRDKSQDGYGIGLSLCQGIIRAHYGQIWVDSVPDKGSCFHFTLPVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2T3</accession>
    <name>A0A2G4F2T3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Photosystem I reaction center subunit XII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_007455</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cellular thylakoid membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the phycobilisome linker protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56060">
        <property type="protein sequence ID" value="PHX56060"/>
        <property type="gene ID" value="CP500_007455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008213">
        <property type="entry name" value="CpcD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001297">
        <property type="entry name" value="PBS_linker_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038255">
        <property type="entry name" value="PBS_linker_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016470">
        <property type="entry name" value="Phycobilisome"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01383">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00427">
        <property type="entry name" value="PBS_linker_poly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005898">
        <property type="entry name" value="Phycobilisome_CpeC/CpcI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01094">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51441">
        <property type="entry name" value="CPCD_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51445">
        <property type="entry name" value="PBS_LINKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <feature type="domain" description="PBS-linker" evidence="8">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="CpcD-like" evidence="7">
        <location>
            <begin position="237"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="289" mass="32114" checksum="BE31DCC6D37A1D8E" modified="2018-01-31" version="1">MAITTASSRLGTSALSDAPKVELRPNYTKDDVEAVIRATYRQLLGNDYLMKSERLKSAESLLRDGSLTVREFVRAVAKSELYKTKFLYSSFQTRTIELNYKHLLGRAPYDESEVVYHLDLYQTKGYEADVDSFIDSVEYQESFGEDIVPYYRGFDTQRGQKTVGFTRMFRLYRGYASSDTAQLEGNNSRLAVELGTNSATAVIGPSGGNEGWAYRASARNMTPSSGFGGAAAYGKEGKMFRVEVSGIRTGGYPAVRRSSRAFIVPVEDLSSQMQKFQRMGAKIASITPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F328</accession>
    <name>A0A2G4F328_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56148">
        <property type="protein sequence ID" value="PHX56148"/>
        <property type="gene ID" value="CP500_006800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="60" mass="6495" checksum="E6CDEEE92BD65B3B" modified="2018-01-31" version="1">MGIGNWELGIGHWALGIGHWELGIGHRALVNSQQLTVNSQQSTVNSQQSTVNSQLTKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3C0</accession>
    <name>A0A2G4F3C0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar assembly protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56274">
        <property type="protein sequence ID" value="PHX56274"/>
        <property type="gene ID" value="CP500_006315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="43831" checksum="50BBFC60793CB5AC" modified="2018-01-31" version="1">MTRFIHDRFAKEFLEELLSPIGTVNIGRDVTSEVREIDVYFTPGIAIPEYSENLGLLGKMASMTAIFEPFRNPVNVAEAISCVIKLWNLRGELQRGAKRKNTPYDDADLPRLWILTPTASKALLEGFAAIPNPQNWVEGIYFFPGHWESAIVVIHQLPETPETLWLRILGKGKVQQRAIAELSVLATDNPLRITALELLYRLQSHLVADIPQELEPEERELIMTIAPLFQQQIQAAQQQAREEGLEQGLEQGLEQGLEQGLEQGLEQGLERGRQEQQRLILENFLRVRFGELSPKMTAFLSPISKLSAAEFTVLLLAISMLTVDEAGREQAVKLLAESVLKLFVTNLEDLLPQAVTNLLALPIAELTFFVEQLPQLSDAELREKLGKIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3D0</accession>
    <name>A0A2G4F3D0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF92 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_006385</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56284">
        <property type="protein sequence ID" value="PHX56284"/>
        <property type="gene ID" value="CP500_006385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002794">
        <property type="entry name" value="DUF92_TMEM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353">
        <property type="entry name" value="PTHR13353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="292" mass="30843" checksum="5CCFA1BD2CD4BD30" modified="2018-01-31" version="1">MQNSELFFNYLSWSNPWLVAIALNTILLAIATITPKKLLTPAGQFHGWLLGVTIWGCLGWQGYAVVMFYFLVGSSVTRIGKAQKEAEGIAEKRSGARGPENVWGSALTATLCALGVLALSILGDTGNIVGETGSILEQTGKMPVPQNIILPVPQYVVSLLLLGYAASFCTKLSDTCASEIGKAYGSRTFLITTLQPVTRGTEGAVSLEGTLAGIVGSIAIALLSWSVGLIDLTGIVFCVIAAFIATNIESVIGATIQSKFEWLTNEVVNFFNTLIGAIAAIVLASAWTAFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Q2</accession>
    <name>A0A2G4F3Q2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleotide pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56376">
        <property type="protein sequence ID" value="PHX56376"/>
        <property type="gene ID" value="CP500_005780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11532">
        <property type="entry name" value="NTP-PPase_COG4997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038735">
        <property type="entry name" value="MSMEG_1276-like_NTP-PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="12834" checksum="98BA33C37DDB57FA" modified="2018-01-31" version="1">MEKEYYKLVRDRIPEIIRQSGNECEVVILSETEYRQALRHKLIEEAGEVAEANGDELVAELADLYEVIDALMLSYGISGDRILEAQVKRKEERGSFTQKIMLLRTSSIKGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3S6</accession>
    <name>A0A2G4F3S6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56433">
        <property type="protein sequence ID" value="PHX56433"/>
        <property type="gene ID" value="CP500_005355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="196" mass="22122" checksum="AAF135C8881ED5AE" modified="2018-01-31" version="1">MESQTIALHSPLELTLELTDEQFFQLCQNNRDLRFERTANGDLIIMPPTGSETGNCNSELSFQLQFWSRQNKPLGLAFDSSTGFKLPDGSDISPDAAWVRRDKWDALTAEQKKKFAPICPDFVVELRSASDSLEKLRAKMKVYIKNGAKLGWLLDRKNRQVEISRPDKDVEILYSPATLSGEDVLPGFVLDLSDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F410</accession>
    <name>A0A2G4F410_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bifunctional cobalt-precorrin-7 (C(5))-methyltransferase CbiE/decarboxylating cobalt-precorrin-6B (C(15))-methyltransferase CbiT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_004910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56500">
        <property type="protein sequence ID" value="PHX56500"/>
        <property type="gene ID" value="CP500_004910"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11644">
        <property type="entry name" value="Precorrin-6Y-MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012818">
        <property type="entry name" value="CbiE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006365">
        <property type="entry name" value="Cbl_synth_CobL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014008">
        <property type="entry name" value="Cbl_synth_MTase_CbiT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036428">
        <property type="entry name" value="CobL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02467">
        <property type="entry name" value="CbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02469">
        <property type="entry name" value="CbiT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="402" mass="43091" checksum="6BF431AF459CE2F2" modified="2018-01-31" version="1">MEKWLSVVGIGEDGLSGLSAIARVQLDRAQVVVGGARHLAMLPTDDTREQLVWQSPLQATIDEIIRRRGESICVLASGDPMCHGIGVTLSRRIPISEMTIIPAASAFSLICARLGWALADVETFSLTNRPVSSIALSLYPGARLLVLSADRHTPDLVAKMLTIRGFGCSLMTVFERMGAGLERRIEGVAAAWNVLDLADLNAIAIAVAADRETLIFPRTSGLPDSAYLHDGQLTKREIRAVTLSTLAPIPGELLWDVGAGCGSIAIEWMRSHRGCRAIAIERHPTRLQYIAENASNLGVSELQIVQGEAPSALANLPQPDAIFIGGGVTAESVLENCWDALGEGGRLVVNAVTIESEFKVLQWHSLHGGELIRIGIQRVGAIGSFQGWKPLAPVTQWAVVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F429</accession>
    <name>A0A2G4F429_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Precorrin-8X methylmutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_004900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CobH/CbiC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56499">
        <property type="protein sequence ID" value="PHX56499"/>
        <property type="gene ID" value="CP500_004900"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016993">
        <property type="term" value="F:precorrin-8X methylmutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003722">
        <property type="entry name" value="Cbl_synth_CobH/CbiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036588">
        <property type="entry name" value="CobH/CbiC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02570">
        <property type="entry name" value="CbiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63965">
        <property type="entry name" value="SSF63965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiC" evidence="5">
        <location>
            <begin position="10"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="209" mass="21839" checksum="97CDC1B7E8BC377B" modified="2018-01-31" version="1">MIDYIKDGTEIYTKSFATIRAEADLSTLSEDLESVAVRLIHSCGMIDIVTDLAASPGAATAGYNALAAGAPILCDSRMVAEGITRKRLPADNPVICTLWHPEVPELAIKIGNTRSAAALDLWLNDLEGAVVAIGNAPTALFRLLEMLDDGAPKPALILGFPVGFVGAAESKAELAENSRGVPFITVHGRRGGSAMATAAVNALAKKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4B6</accession>
    <name>A0A2G4F4B6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sodium-dependent bicarbonate transport family permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56600">
        <property type="protein sequence ID" value="PHX56600"/>
        <property type="gene ID" value="CP500_004490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010293">
        <property type="entry name" value="Sbt_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40400">
        <property type="entry name" value="PTHR40400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05982">
        <property type="entry name" value="Sbt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="324" mass="34752" checksum="198CD1B3D27CFB97" modified="2018-01-31" version="1">MDLSLVASNLLNPPVLAFFMGMLAVFLKSDLEIPAPIPKLFSLYLLFAIGFKGGVELAKSGFNQQVALTILAAMLMSALVPVYTFFILRIKLDAYNAAAIAATYGSISAVTFITATSFLTEQGIDFNGYMVAALALMESPAIIVGLILVSVFGGGEEGKRDIVWSEVLQESFLNSSVFLLIGSLIMGILTGEHGWEVMSPFTQDLFYGVLTFFLLDMGLVAASRIKDLQEAGVFLIGFAILIPIVNAVIGLVIAKLIGMPQGDALLFSVLCASASYIAVPAAMRLTVPEANPSLYISTALAVTFPFNIIVGIPVYLYGINMFWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4M8</accession>
    <name>A0A2G4F4M8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56447">
        <property type="protein sequence ID" value="PHX56447"/>
        <property type="gene ID" value="CP500_005445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="14002" checksum="8355EE4D3CC7BAB2" modified="2018-01-31" version="1">MDSLNNYRQLVKQLLNEYAEIPVFDSGTQNETIFDVENDRYMLINIGWFNEQRIHHCVIHIDIIDGQVWIQANNTDRLIAEELVAAGIPAKSIVLGLQPPDVRPYTAYGVPSKQHQRESLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F501</accession>
    <name>A0A2G4F501_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">secE</name>
        <name evidence="9" type="ORF">CP500_002970</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cellular thylakoid membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56852">
        <property type="protein sequence ID" value="PHX56852"/>
        <property type="gene ID" value="CP500_002970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33910">
        <property type="entry name" value="PTHR33910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01067">
        <property type="entry name" value="SECE_SEC61G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8589" checksum="C6F5F05438D4A561" modified="2018-01-31" version="1">MAKKDEAQQTQEIAAPGFDPTGFLKETREELDKVVWPSRQQLISESLAVLLMVILSASLIYLVDNFFNWGAAQVFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F573</accession>
    <name>A0A2G4F573_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NlpC/P60 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56953">
        <property type="protein sequence ID" value="PHX56953"/>
        <property type="gene ID" value="CP500_002780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041382">
        <property type="entry name" value="SH3_16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18348">
        <property type="entry name" value="SH3_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NlpC/P60" evidence="2">
        <location>
            <begin position="99"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="26957" checksum="B49A18643E46FC5A" modified="2018-01-31" version="1">MANYQLSDVLEYRVRSHINIYDSPKCDRLATQAAAGRHLRIVDRPLIDDERGVNFETTAVMVRLCEDDYPGWLDIRDVELLDVADTFYHREIFSEAEIRAKLPTVIDFAHQAMKQSNYYLWGGTVAPNYDCSGLMQAAFLSANIWLPRDAYQQEAFTNPISISDLEPGDLVFFGTPQKATHVGLYLGDNRYIHSSGKEQGRNGIGIDVLSEDGDKVSQIYYRQLRGCGKVVASYQSGNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5E9</accession>
    <name>A0A2G4F5E9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57033">
        <property type="protein sequence ID" value="PHX57033"/>
        <property type="gene ID" value="CP500_002270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="11743" checksum="ECA85F5C1F0FE279" modified="2018-01-31" version="1">MRKDSPLSRATLTHLNIERLKGTLSYFSHLNATGEISDKSYEALVRYACAVFIETGIEDIVQNSLEQKLESFLLSRILRVDNLLSEQEESSLNLDISRLLKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5G6</accession>
    <name>A0A2G4F5G6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57043">
        <property type="protein sequence ID" value="PHX57043"/>
        <property type="gene ID" value="CP500_002320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="SSF101967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="8597" checksum="CAA83A431A128830" modified="2018-01-31" version="1">MGNWALGMGNWAWGIGHGELGMGNWALGIGHWALGMGHWAWGIGHWALGIGHGELGIGHWALGMGNWAWGIGHWALGIGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5I6</accession>
    <name>A0A2G4F5I6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1997 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57063">
        <property type="protein sequence ID" value="PHX57063"/>
        <property type="gene ID" value="CP500_001935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018971">
        <property type="entry name" value="DUF1997"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09366">
        <property type="entry name" value="DUF1997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="26700" checksum="7296CE7B1637A736" modified="2018-01-31" version="1">MKQDSAEYPTIEASDEICYPDGSFQPPETGGADVAEDVELIWFSTHFEDSMEMYADAATVAEHLNNHKTWFCQCALPMKAEPIGENGYDLLIGRFGAFGYRVEARIGLELLPPDAEGCYLIKTIPVPNYTPPGYEVNFCSAMNLMELSADDFAKNWSISDRSQLPPLITIAGWKLDLAVGVYFPKFIRSMSKSLIQKTGEGILEKIIKQVNRRLTYKTQLVFHESLGIPFPKKPHKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5M4</accession>
    <name>A0A2G4F5M4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57103">
        <property type="protein sequence ID" value="PHX57103"/>
        <property type="gene ID" value="CP500_002090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9303" checksum="60AA06383D96A13B" modified="2018-01-31" version="1">MKAIKVMATIDNKGQLYIDEPLKLRQNSRVEVIVLIPELIEINEQEQSKEAILADFRQAWHEAMTGKTIPVVEIWEGIDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5N5</accession>
    <name>A0A2G4F5N5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57113">
        <property type="protein sequence ID" value="PHX57113"/>
        <property type="gene ID" value="CP500_001545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="14718" checksum="8C0F1E29D117E00B" modified="2018-01-31" version="1">MNKPVIVCVDDEPDILNTLKMQLKNEFKDNYFYELAESADEALEVIEGFQGEDQVIVVVSDWLMPGIKGDELLIRIHEKHPKIVKVMLTGQADTAAIQRAVEHADLFCCLYKPWTSEDLIKTIKSGLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5P1</accession>
    <name>A0A2G4F5P1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57092">
        <property type="protein sequence ID" value="PHX57092"/>
        <property type="gene ID" value="CP500_002100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="94" mass="10706" checksum="EEEA0BEFE27BC1C8" modified="2018-01-31" version="1">MKNQTDNGFHNDLVDRTFASSAIPDPAQWVNEHHFLANFANQLSYLQQHLSDDCLETGDSCDRAEGELAIDAKIREILKASLSDDYWQYVEGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5U5</accession>
    <name>A0A2G4F5U5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">clpX</name>
        <name evidence="10" type="ORF">CP500_001515</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ClpX chaperone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57109">
        <property type="protein sequence ID" value="PHX57109"/>
        <property type="gene ID" value="CP500_001515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ClpX-type ZB" evidence="9">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="150"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="51043" checksum="624ECA9E2807FD89" modified="2018-01-31" version="1">MSKYDSNLRCSFCGKSQEYVRKLIAGPGVYICDECVELCNEILEEEFFDSGKTVAQQVPQSETQESQGQKTRRGRSNKPKIVLAKIPKPTDIKQHLDNHVIGQNSAKKVLSVAVYNHYKRLSVDQAKDSGKSSPDSDVELQKSNIMLVGPTGCGKTLLAQSLAQMLEVPFAVADATTLTEAGYVGDDVENILLRLLQMSDFDVEAAQRGIIYIDEIDKIARKSENTSITRDVSGEGVQQALLKMLEGTVVNVPPQGGRKHPYQDFIQIDTSKILFICGGAFVGLEKIVEQRLGKKSLGFIQPVESDSNSTLLPKDKRVADILQQVQPDDLVKFGLIPEFVGRIPVVTVISPLDEAALMQILTEPRNALVKQYQKLLNMDSVELEFEPDALRAIAQEACRRKTGARALRSILEELMLDVMYELPSRKDVANCIITAEMVEKRSTAELLWHPAWRKQHETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Y1</accession>
    <name>A0A2G4F5Y1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyanate hydratase</fullName>
            <shortName evidence="3">Cyanase</shortName>
            <ecNumber evidence="3">4.2.1.104</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Cyanate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Cyanate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">cynS</name>
        <name evidence="5" type="ORF">CP500_001520</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>cyanate + 3 H(+) + hydrogencarbonate = 2 CO2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:11120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29195"/>
            <dbReference type="EC" id="4.2.1.104"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyanase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.104" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57166">
        <property type="protein sequence ID" value="PHX57166"/>
        <property type="gene ID" value="CP500_001520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008824">
        <property type="term" value="F:cyanate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009439">
        <property type="term" value="P:cyanate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00559">
        <property type="entry name" value="Cyanase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00535">
        <property type="entry name" value="Cyanate_hydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008076">
        <property type="entry name" value="Cyanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003712">
        <property type="entry name" value="Cyanate_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036581">
        <property type="entry name" value="Cyanate_lyase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34186">
        <property type="entry name" value="PTHR34186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02560">
        <property type="entry name" value="Cyanate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001263">
        <property type="entry name" value="Cyanate_hydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01693">
        <property type="entry name" value="CYANASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01116">
        <property type="entry name" value="Cyanate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55234">
        <property type="entry name" value="SSF55234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00673">
        <property type="entry name" value="cynS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyanate_lyase" evidence="4">
        <location>
            <begin position="75"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="147" mass="16350" checksum="D2285ED59DD83D80" modified="2018-01-31" version="1">MAISKITEKLLAAKKAQGISFADLEKVLDRDEVWIAAVIYRQASASLDEAQKIVSALGLEDEMAQVLSEPPLKGSLDAGVPVDPLIYRFYEIMQVYGMPLKAVIHEKFGDGIMSAIDFTLDVEKEEDPKGDRVKIIMSGKFLAYKKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Y7</accession>
    <name>A0A2G4F5Y7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Riboflavin biosynthesis protein RibD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Diaminohydroxyphosphoribosylaminopyrimidine deaminase</fullName>
                <shortName evidence="10">DRAP deaminase</shortName>
                <ecNumber evidence="10">3.5.4.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">Riboflavin-specific deaminase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">5-amino-6-(5-phosphoribosylamino)uracil reductase</fullName>
                <ecNumber evidence="10">1.1.1.193</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">HTP reductase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">ribD</name>
        <name evidence="15" type="ORF">CP500_001255</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21868"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6-(5-phospho-D-ribosylamino)uracil + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17845"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58421"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="EC" id="1.1.1.193"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 13">Binds 1 zinc ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">In the C-terminal section; belongs to the HTP reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.26" evidence="10"/>
    <dbReference type="EC" id="1.1.1.193" evidence="10"/>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57182">
        <property type="protein sequence ID" value="PHX57182"/>
        <property type="gene ID" value="CP500_001255"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004794">
        <property type="entry name" value="Eubact_RibD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011549">
        <property type="entry name" value="RibD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006769">
        <property type="entry name" value="RibD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00326">
        <property type="entry name" value="eubact_ribD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00227">
        <property type="entry name" value="ribD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10 12" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="8 10 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="26"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX57182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="385" mass="41216" checksum="447474CACA582DCA" modified="2018-01-31" version="1">MATFPTDASAIANSTKQLENSAEIQEFDRAMMRRCIELARRALGQTAPNPLVGAVIVRDGKIVGEGFHPGAGKPHAEVFALREAGELAAGATVYVNLEPCNHYGRTPPCSEALIQAKVAKVVAGMVDPNPLVAGTGLARLREAGIEVVAGVEEEACQKLNEAFVHRILYRRPLGILKYAMTLDGKIATSTGHSAWVTGEEARSEVHSVRVGCDAVIVGGNTVRLDNPQLTSHQPDRHNPLRVVMSRSLDLPKSARLWETSSAPTLVLTEPGVNREFQAFLIAKGVEVVELLPLTPANVMTYLYDRSFLSVLWECGGTLAAKAIADGAVQKIMAFIAPKIVGGSEAPTPVGDLGFAEMTDALTLERVSWRTVGADCLVEGYLKSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F602</accession>
    <name>A0A2G4F602_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57214">
        <property type="protein sequence ID" value="PHX57214"/>
        <property type="gene ID" value="CP500_001470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="126" mass="15072" checksum="8F16A9D30F31D89B" modified="2018-01-31" version="1">MTNDSDPNFQIEVQRLHKLTVYGRWLTVIFLWISIGSFSIWGLRDEIALWIENFTWAAVRYGLYFHRWPTLGLGLCLGMTLAVLTWQGRNIVRGLPLREKRRLEEQVRRIRQQGSSHPLWKWVCRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F615</accession>
    <name>A0A2G4F615_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">secD</name>
        <name evidence="10" type="ORF">CP500_001460</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57212">
        <property type="protein sequence ID" value="PHX57212"/>
        <property type="gene ID" value="CP500_001460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="383"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="463" mass="49278" checksum="E88272729BDFB0E4" modified="2018-01-31" version="1">MQKQRSVLALIFVLVIAAITVIATIPTRLGLDLQGGSQLTIQVKTTATIPKIDPGMLEAVRRIVENRVNGLGVSEALVQTVGEDQILVQLPGVNDPQQAERVLGGTAKLEFREQLPGTEAQLAIERQLQQELVAKQAQLKISPDEAAFKANQGALKRSNEAIAKLYKTSALGGDNLKDAQAQPTGNEWNVALRFDTKGGELFGELTKNLAGTGRTLGIFLDEKMISSPVVGVEFAQAGITGGNAVIQGRFTTQEANDLAVQLRGGALPVPVEIIENRTIGASLGRDSIQSSIVAGIGGLTLVLIFMIAYYRLPGVIADIALLIYALLTWAAFVLLGVTLTLPGIAGFVLSIGMAVDANVLIFERTREELRSGKTLYRSVESGFYRAFSSILDGNVTTVIACAALFWLGAGLVKGFAVTLALGVAVSMFTAITCSRTLMLVVLGFPGLRKPEWFCPNLSKTTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6E7</accession>
    <name>A0A2G4F6E7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="11">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rlmN</name>
        <name evidence="13" type="ORF">CP500_001065</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="11"/>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57295">
        <property type="protein sequence ID" value="PHX57295"/>
        <property type="gene ID" value="CP500_001065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="95"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="156"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="209"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="11">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX57295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="336" mass="37563" checksum="FEA184C7F3EE37F8" modified="2018-01-31" version="1">MPPLLGASLAELTEWVQQHGQPAYRGKQLYQWIYERGARSLSEISVFSKQWRETVADIPIGRSTIHYRSVAPDSTIKYLLKLADGQIIETVGIPTEKRLTVCVSAQVGCAMGCDFCATGKGGFKRNLEVHEIVDQVLTVQQDFGRRVSHIVFMGMGEPLLNFDNVVTAVKCLNEDVGIGQRNITISTVGIRNRIRKLAEHHLQVTLAVSLHASNQRLREELIPSAQPYPLDELIAECREYVQSTGRRLSFEYVLLANVNDLPEHAAELAGRLRGFQCHVNLIPYNPIQEAEYQRPTPNRINGFVTVLKEKKIAVSVRYSRGLEADAACGQLRASEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6I7</accession>
    <name>A0A2G4F6I7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57368">
        <property type="protein sequence ID" value="PHX57368"/>
        <property type="gene ID" value="CP500_000030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8566" checksum="DE8AC5633BC554B6" modified="2018-01-31" version="1">MRISSDLTFCTIVKKLFRGELTGPRPKQIYFLWNRPECLLATEVQALSSIAVNLKSQFSSIARPLTLDRAKAAKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUN9</accession>
    <name>A0A2G4EUN9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carotenoid biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000231">
        <property type="protein sequence ID" value="PHX53245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53245">
        <property type="protein sequence ID" value="PHX53245"/>
        <property type="gene ID" value="CP500_022535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007354">
        <property type="entry name" value="CruF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39419">
        <property type="entry name" value="PTHR39419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04240">
        <property type="entry name" value="Caroten_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="313" mass="33746" checksum="B5397F8FD638C176" modified="2018-01-31" version="1">MKQLLIAERICLVAHVLSMAFGLAGLLVILPRPELVVSLSPAGQTLFQWGMVGGGVVYIIFGAAAVALYAFRTLGLGATLTFLLPSVFLSLGSELLGTSTGFPFGNYHYLSGLGYKIAGLVPFTIPLSWFYLGLVCYVIARAGLSGGKGELNWVRQLGAIALGAILLTAWDFVLDPAMSQTSMPFWEFEELGAFFGMPYRNLAGWMGTGALFMSVAAFFWRKTPIHLDRSEMGLPLIVYVVNFAFGAIITVTSLDSRFWFPTLLAVLLGVVPAIVLSAMAKPADKVTETIPPYEDKSALKAEIPPQPVGVLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUP8</accession>
    <name>A0A2G4EUP8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clp protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000229">
        <property type="protein sequence ID" value="PHX53254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53254">
        <property type="protein sequence ID" value="PHX53254"/>
        <property type="gene ID" value="CP500_022495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="328"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="648" mass="73256" checksum="79BFFF34AB7E0BD9" modified="2018-01-31" version="1" fragment="single">RINGSRADNLEVAIAFYDAALTVRTREGFPEKWAMTQNNLATAYSDRITGNRAENIDTAIKCFRQALEIRTPSASPLGCLQSGYYLGNLAFNLQDWENAIYGYENAITAVEQSREWAGTEAAKQEIQENAIDVYFQMLQTCINAKNLPKAVETVERSKARNLVELLATRDLYPKGNIPQEILDQLDNLRRKIPAIQRHLGQKTTNQLSQSNDDTEKQLRSELTALQQQLDRVLAQIKIVDHDFNLTQRVEVIPYSEIQSLAANNTAIIEWYITRDKFLAFVIAPNSLAPIVWQSSTADFNNLENWNNEYVGDYRNNNAQWQQTLTHNLQRLAEILHLDELLNLIPPTCDRLVLIPHSYLHLFPLHALPSKRQKINKESSQLYTATGCLLDLFSDGVSYAPSCQLLQLAKKRHRPNFSHLFAIANPTSDRYLLELQAANIRQGFQSDSFWQRDNANKQAILNDQLSLANCAHFGCHGKFKPDAPLDSALILANNERLTLLEILTLNLSQCRLVTLSACEAGLTETSTTDEYIGLPFGFLLAGSPSMVSTLWEVDQLASTLLLIRFYENIKTLSTVAALNEAQQWLRNLTSEGLEAVLERLKPQIEQTFKELPLKERRRYVNAPLKAASNRQPLPFAAPHYWAAFTAIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV20</accession>
    <name>A0A2G4EV20_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MORN motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000203">
        <property type="protein sequence ID" value="PHX53392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53392">
        <property type="protein sequence ID" value="PHX53392"/>
        <property type="gene ID" value="CP500_021715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="250" mass="26837" checksum="057E90779AF9678D" modified="2018-01-31" version="1">MLGSIQKLGMVILVASCIGSATNLLNPGPSIAQPKDEPKKEEGKRPPVCQGNPPTGKVKCNYEGADNYEGDFVNGLPDGTGVYVYANGDRYQGQFRNGVPNGRGTFIFKDDARYTGIFQDGTMSSGTVIFPNGERYIGDFGVVRNVQTNVISSQPAGRGQFFYSNGDRYEGQFFAGSPFGPGVLVRADGTRCSGRFFNLELDASVTCTFPNGTRYEGELRKGLPHGVGTMIDASGRRFPGVFRNGKPGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV83</accession>
    <name>A0A2G4EV83_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53441">
        <property type="protein sequence ID" value="PHX53441"/>
        <property type="gene ID" value="CP500_021505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="68" mass="7576" checksum="65C2D7B218AF6C7B" modified="2018-01-31" version="1">MVENTVDCVVACVNGCVLGDKCPKREYAAATSSFIENTSLDKILEMAEEAVKKKRMEPPKWVIPDFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVX9</accession>
    <name>A0A2G4EVX9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000163">
        <property type="protein sequence ID" value="PHX53679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53679">
        <property type="protein sequence ID" value="PHX53679"/>
        <property type="gene ID" value="CP500_020195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="272" mass="30555" checksum="95268940DEE184B7" modified="2018-01-31" version="1">MMRSLLRFLTVIIVTGLVCFGNIMPAAAQVETTDITDPQQELGELVQKAFEATNEGKFPLAESFWTQIIDKFPDQAAAWSNRGNSRVSQNLLKEAISDYEKAMELVPNAPDPYLNRGTALEGLGRWEEAIADYNHVLELDPKDPAAYNNRGNAEAGLGQWKQAIIDYNKAFELAPEYAFARANHALALYQNGQSKEAIRNMKNIVRRYPQFADMRAALSACLWEAGQRGEAESNWVAAVGLDSRYKDLDWVKNTRRWPPVVVSALDKFLNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW39</accession>
    <name>A0A2G4EW39_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Receptor ligand binding family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000162">
        <property type="protein sequence ID" value="PHX53688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53688">
        <property type="protein sequence ID" value="PHX53688"/>
        <property type="gene ID" value="CP500_020145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="146"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="479" mass="50452" checksum="84FC5C4C966A7FB5" modified="2018-01-31" version="1">MSQRNETVILVLSLVITMGLVGAGIWWITKSKGINLGSVSSEKLISGTSPTANASDSQLSIGQRLSIGKKLLIPEGSSQKKQEAVQAIASLNYNTAIANLEASLQASPNDPEALIYLNNARIGDKKSYTIAVAVPIGKDMNPALEILRGVAQAQNELNQSGGLSGIPLKVLIANDDNNPEIASQIASDLAKNSEVLGVIGHFGSDTTLAASKVYQQNQLVAISPTSTSVQLSGVGSNIFRTVPSDRFAANALSRYMLTKLQKKKAVVFFNSASSYSKSLKNEFTTAVYADGGQIVSEFDLTNPNFNAAESVKKAIAQGAEVIMLASNSSTIDQALQVVQVNAKRLPLLAGDGAYTAKILQIGGAGATNMVLAIPWHILADPQSNFPQTSKQLWKAEVNWRTALAYDAATALIAGLRVNPTRTGIQQALSASDFSATGASGAIRFLPSGDRNRAVQLVTVKPGNRTSYGYDFVPISGSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW98</accession>
    <name>A0A2G4EW98_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53815">
        <property type="protein sequence ID" value="PHX53815"/>
        <property type="gene ID" value="CP500_019515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="11819" checksum="B61F06E06DC07152" modified="2018-01-31" version="1">MEYDIQLTPLALEMLAEVKDRREQEKLRDRIDKLKIEPEKQGKALVDNLSGFRSIRAVGQRYRIVYKVEQDRVMVVVVGLGRRKDGDKKDIYSILEKLSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW99</accession>
    <name>A0A2G4EW99_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tat pathway signal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000150">
        <property type="protein sequence ID" value="PHX53832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53832">
        <property type="protein sequence ID" value="PHX53832"/>
        <property type="gene ID" value="CP500_019340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="260" mass="28279" checksum="EA5BE1AF8C3BDD71" modified="2018-01-31" version="1">MSISRRQFNRIVIWGGASFAASATSGIFFPKPAEAYSLEFPISALSADRVFNGIQKYCGAQPIPGVLSTILQGNTNVSSQIKPAAANAIRTADKEFVDRNFTSKRTELGQVGKSEEDNTLSVSRLWGRQRQENVGPNVGFGFVQRWEDQYSDTKISGPTMCAIHNAQRVLADQRLTPPEIAASVLPTRSRLDDTSSWGGDADASAGRNPGAVFAQYTTAAGTVTSRYDLVEPGPKGFGRVEFTIEAENQPRRVILVTVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWI8</accession>
    <name>A0A2G4EWI8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53800">
        <property type="protein sequence ID" value="PHX53800"/>
        <property type="gene ID" value="CP500_019465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="3"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="139"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="173"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="207"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="347" mass="39723" checksum="7C96A0669BC93BB4" modified="2018-01-31" version="1">MNLKQFYKRGLQSAKNGNYEAALGDFGQILQLNPADAKAYNNRGLVYYYMKDYQKAIADLSQALDINPNLFEAYLNRGNAWRHLGEHEKAIEDLNCALVNNPESHAIYNNRGLVLANLGHYEEAIKDYDRALSINSQNYKTYYNRGRAYYLLGNKEAAIEDFNETLRLNPEYIKAYINRGLSHHQLGGNPAAIADYNTAIGIDPENVYAYYNRGCVRYKLKQMKLAIEDFDKAVEIDPSYVKAYLNRGLALYKLGDIMTANKDFYHVMCINAEAYSYYQAQRCTPDINSYFKEAPQMESNNAVEYYNTTLNNTISTSFSSAALNSVWNQKDLDKRDSIICEGEFMND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWX4</accession>
    <name>A0A2G4EWX4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000129">
        <property type="protein sequence ID" value="PHX54052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54052">
        <property type="protein sequence ID" value="PHX54052"/>
        <property type="gene ID" value="CP500_018210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14072" checksum="782AB104AC8C59B9" modified="2018-01-31" version="1">MNNVKAPTSRSYQELLIASLRNAQEAAGYIEVTLTEASDEPKLLQMVLKDVIDSRLKFHNLSESAKLQWEKLDKMLTASSGSEIYCFVELLEALGFKLGITVEDGELGGDSESMIEESKLSRETANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWY7</accession>
    <name>A0A2G4EWY7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53988">
        <property type="protein sequence ID" value="PHX53988"/>
        <property type="gene ID" value="CP500_018620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046031">
        <property type="entry name" value="DUF5989"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19451">
        <property type="entry name" value="DUF5989"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="54" mass="6344" checksum="5D4295D36AFF8A4C" modified="2018-01-31" version="1">MFEATLDFLKDLWAFMKERQKYWLLPLIMTLVFLGALIVLSQGSVIAPFIYTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWZ4</accession>
    <name>A0A2G4EWZ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54072">
        <property type="protein sequence ID" value="PHX54072"/>
        <property type="gene ID" value="CP500_018080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="498" mass="56093" checksum="A49FDBEA3E4E355B" modified="2018-01-31" version="1">MNLPVIIDIIIGLVFIYLSLSLLASEIQELIATVLQWRAEHLKKSIEVLIAGGNEGAQDEAEFQRVGELANLIYSNPIISDLNQGAQGPLPQIFRSLIHSLGAFYRRLSGRKNVFGDKSTGPSYIPSESFSSSLLDTLKINQLIKSITEARLKRFKDLQLTQIKVIGEGLKLSESTQPIIDQEFVWLTGEFERVIEDYKNDLVTLNNSLDRMSEKLGFYISDSQVYLPEAELEGREFQRQMGFIKANFDSEFERAALRKQLQPSLSNVLNKIRKVRKTEETITEILEEKEDSPIYQQIQATVDSMPEALKNSLYILAQRAEKDGGDSQEQLQRFQREIEVWFDRSMERASGVYKRNSRGVAILLGTAIAIGANADTINIINRLSKDSMLRSTVNLYAQQLVERNPATKLDDLPSITKIQNEVGIALDNLAVPFGWSEPNRVEIDSQGNILWPAFVRKFFGWVLSGLAISMGAVFWFDVLSKIINIRNAGKKPPSTTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX12</accession>
    <name>A0A2G4EX12_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TldD/PmbA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_018090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54074">
        <property type="protein sequence ID" value="PHX54074"/>
        <property type="gene ID" value="CP500_018090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="20"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="213"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="434" mass="46962" checksum="0B8823869E103EC3" modified="2018-01-31" version="1">MSDSTIEQILKLASQRADAAEVYYLSSQDTPIEFENNRLKSLQTKALRGVALRLIHNGKIGFASSTDLTRVDDLVDAAIQTAEIGDPAEFELASDFHLITPETTYTPPTTAELVENGKNLIQQVHAYNPDIIVDVGFHVRSGRVTIATTQDVYAQRSSQIVSATIAGNLVQGEDFMQAYSYDVACDRAIDTNNILQTLLEKYRLAENAATITSGSYPVLFTPNAAASTLGNLFNTILSGQTVVQKSSPLADKIGKTLFDERFSFFEDPTLGPSACPFDDEGTPTTRKVLIDKGTVTGFYWDRRWAARGGVESTGNGFRGGLSRPGPNLTNFCISPGNTPIQELIASMEEGLIVEQVLGAGQSNQLAGEFSVNLDLGYKVEKGKIVGRVKNTMVAGSIFEAFKNLVDLSSESEWVGGGAYLPSMLFQQLGVASRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX78</accession>
    <name>A0A2G4EX78_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54152">
        <property type="protein sequence ID" value="PHX54152"/>
        <property type="gene ID" value="CP500_017655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="12838" checksum="7D5C4F63F22BFB89" modified="2018-01-31" version="1">MNLSFKDLRFIIEAIEHQINAYQERLQVIEDVDEDEAADLGNDIKFLELLHADMTTTLEQNTTEREDIAYEQALSEALEETFAEWETIEAMTAEEACERIRAISNQALEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX82</accession>
    <name>A0A2G4EX82_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000122">
        <property type="protein sequence ID" value="PHX54131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54131">
        <property type="protein sequence ID" value="PHX54131"/>
        <property type="gene ID" value="CP500_017765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="227" mass="25512" checksum="A44F0329BFD6A953" modified="2018-01-31" version="1">MPKARKPPQPKPQQLLVEGKNDRHVIWALCQQYQLPETFSVEVPQEEGTEGVEALLNGLPERLKAENLRTLGIVVDADRNLSARWQSVKDKLSSIGYRDIPQSPPPEGWVCTPSDPYLPRVGVWLMPNNQLPGMLEDFVAYLIPPGDTLHPKAEAILQELEQAGLNRYSLIHHPKALIHTWLAWQKNPAMPMGQAITAQVLSYDSPITLIFIEWLKHLFELIAPSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXB1</accession>
    <name>A0A2G4EXB1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000127">
        <property type="protein sequence ID" value="PHX54080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54080">
        <property type="protein sequence ID" value="PHX54080"/>
        <property type="gene ID" value="CP500_018125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="403" mass="43353" checksum="AC039FA98E2D1120" modified="2018-01-31" version="1">MNIMALIPDAYFAVTDHTVEVSQESFRSVISQIEAELLCSDTYSHALASLQTMLGEAASAAEILIRAVSREAVKLTFQRFPKTQKTELQALQESPALASPTITSTAITSPTFGSSALTTATEFTAVRELEPSQVSVQVFYRSPVTTVEVPPKIESDTKNGGFYTETDEANKELPKYEGQVESATPGAVVVQGNSFPEFSFLQKHKKLTKEETVALAIQQRKDCLCELGRELRQGRELRSLSIQHLHSLTLVPLHHIESIENGEIEKLPQDIYVRGFIRRIGDAVGLNGNAMADALPKLDSSETLYSYSSASDSDSADGFQMNSAHLYIGYTALMAGALGGVAWLSQQPVVPPSAPEAQVTPPASVAPAQKGETPAPRPGVKKSTTHGGMILGAGMSPPEMIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXD7</accession>
    <name>A0A2G4EXD7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF86 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_017240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54212">
        <property type="protein sequence ID" value="PHX54212"/>
        <property type="gene ID" value="CP500_017240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008201">
        <property type="entry name" value="HepT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01934">
        <property type="entry name" value="DUF86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="12823" checksum="163BC6175981199D" modified="2018-01-31" version="1">MSANRDMASLLDIVQAGEMIQRYLTGIDSEELAASDEKQAAIIYRIIVIGEATKRISSEFRAEHPEIPWKDMAGMRDWVSHAYDRVNLDIVWDVAQNKIPQLLVQIKPLIAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXG6</accession>
    <name>A0A2G4EXG6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_017205</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54242">
        <property type="protein sequence ID" value="PHX54242"/>
        <property type="gene ID" value="CP500_017205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003790">
        <property type="entry name" value="GHL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02638">
        <property type="entry name" value="GHL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SLH" evidence="3">
        <location>
            <begin position="3"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="3">
        <location>
            <begin position="67"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="3">
        <location>
            <begin position="130"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="676" mass="76189" checksum="4267125EAE5895E5" modified="2018-01-31" version="1">MVSNNISFSDIQNHWARQFIEGLTERAIISGFPNRTFGPNSNLTRAQFATIVSKAFPTPDKRAYIPFTDVPATHWAAAAIQTAFNRGFISGYPKNLFKPENRITRVEALLALVSGLFDASAAPPTDIVLSNIYQDSTEIPNFAKSAIAKATQAEIVVNYPNLKLLNPAGNATRADVTAWVYQALVYLRRAPKLPSQYIVTIGKNPQQPPSTVQVSHQREFRAAWVTAVWNIDWPSSPKLSTEEQKNQLLKILNRLEEMNFNAVILQIRPEGDALYASELEPWSAWLTGTQGKPPEPYYDPLEFAISESHKRNIEVHAWFNPYRAKVSTKTSANVSPHISVTNPESVCAWGDKLWMEPGNSTVQDRTYNVILDVVKRYDIDGIHFDDYFYPYPIQGQEFPDSKTYNNYRSQGGKLSLGDWRRENVNTLIKRVAEGIKSTKSHVKFGISPFGIYRPGQPPASRGLDSYEVLYADSKKWLELGWVDYLSPQLYWRIDETAQSYPMLLNWWVENNPKQKHIYAGNNLGLLDGKKWTAGEINKQIEITRNLDQKLALGNIFFSMRAFTENRQQIYDVLKSTIYANLALVPAMPWLKGTPPPIPTGVEVKKVANNTVLGWNNSADNNIRSWTLYQKNGNSWKLIKILDAETAEVAIQSGTYALCAVSRMAMESAGVLVVISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXI0</accession>
    <name>A0A2G4EXI0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family intramembrane serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_017215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54243">
        <property type="protein sequence ID" value="PHX54243"/>
        <property type="gene ID" value="CP500_017215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="68"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="234" mass="25663" checksum="CAA7C81004A20C44" modified="2018-01-31" version="1">MVPLRDENPTRITPYVTYGLIAANVLVFLYELSLGDRQLTQFFYSWAVVPCQLTNICRVSLPVSQFPEWTTLISSQFLHAGFLHVAGNMLFLWIFGNNVEDCLGHIKFIIFYLTCGVLASLTQWFFSPASAIPSLGASGAIAGVMGAYILRYPQAKVLTLLPLGIFITTVRIPAFFFLGFWFVQQAFNGVTSLNAPAKVGMESGGVAYWAHAGGFVFGAILGPLLGLFSEDNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXT7</accession>
    <name>A0A2G4EXT7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54354">
        <property type="protein sequence ID" value="PHX54354"/>
        <property type="gene ID" value="CP500_016495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="27"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="144" mass="16054" checksum="5AD9C4C51A2BAF5B" modified="2018-01-31" version="1">MNYLNRNQDLEYSSANSDRLLLHKRPLVLAVDDNQDNLELLAQILDLFGCEYVGAQDGSTALSAAASRLPDLILLDICLPDIDGIELVSRLKQNLQLINIPIIAITALAKTEDRDRILQAGCVGYLSKPFDIDKLEAIIYRHVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXV1</accession>
    <name>A0A2G4EXV1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000106">
        <property type="protein sequence ID" value="PHX54365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54365">
        <property type="protein sequence ID" value="PHX54365"/>
        <property type="gene ID" value="CP500_016555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="36679" checksum="1AD727903E502F17" modified="2018-01-31" version="1">MEDFGVIIACCDQDYLFAKGCCASIRYFLGDVPICLLIDGTFSVTPLEKVYGVRVINHDSVSEPLLRKRSFGWGKSHMIPFWESPWQNFLVMDADTIVWGDVLKLANFQDFDFIIDQPCYDYSDADITEFFFDIPGVEKYFPDFRWQEYRSRYVCPGTFFGKRGVFSLEEYRKILDFNDEHPEIFKYGDMGFFNLMVFRAAQEGKLRVQNVDMQLLAPDFDQDLLRKRFPIESSGPGGDRTQATVIHWCGPKPTLSTSKVYSEPMNFCRRKCQEDVWNRTGLAAEMLLQVEDLQRSIYVYKNKFKKKFRQLTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXZ5</accession>
    <name>A0A2G4EXZ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40 repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54402">
        <property type="protein sequence ID" value="PHX54402"/>
        <property type="gene ID" value="CP500_016290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037783">
        <property type="entry name" value="Taf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="PTHR19879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="577"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="620"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="662"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="704"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="746"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="789"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="831"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="865" mass="97859" checksum="6618CA32A4935F95" modified="2018-01-31" version="1">MPQPNLQRTTLNDQSALATAILLKKPGFLENSGFCKHNFTSGEMIMIWNFAQGIITAVNGILGPQTVMAMTQRQNEIDRIASQIEMQNRSLEFQAAMEGVRQEHSKEMEAYRQYCEDVRLQKRLDSEREQLARRFQHEEKLEQYRRETHLILSRAQLLTALTLADDKEIRETFPLKTPARVILDAYKSYQENMKQIPLLVVISPPALQFEKFPHVAQGFGLVENRLIDEIQEFCKHYSITNQERPVRYQGADWESKYSHGKTGIDTLHHVLKSVPTVVLESKFDGDLLRVYVAGWDMMQEVPHYEKVLTIPWKEVLYPIARKYAEEWREYRMKLLEKGRSLEELKRRGGDNELNLLILEEEEEDRELGRGGQHDYQYNVKEDKYIQELAQFLGICHCILVGLMADRYHFYHGDVRPKLPELLPGLLEKMPSNSLNEMLVGEIVSSYQSLYQSIEGKRPNAIPYLLLDLALSLSGLSDKSWAKKQVEFSIKAWLKLRNGVSEEKLGLLNLENLLEVFKSTLTVADSEYVEKLTGCLAAIGESRYREMIGEDIKAERQRQREEVERKRKLENVSVVHTLTGHSDGVNYVAISPDGQTLVSCGDDDTTIKIWQLSTGRELRTLTGHSDSVGSLAISPDGQTLVSGSDDKTIKIWQLSTGRELRTLTGHSDSVGSLAISPDGQTLVSGSDDKTIKIWQLSTGRELRTLTGHSDEVWFVAISPDGQTLVSGSRDQTIKIWELSTGRELHTLTGDYLWASSLAISPDGQTLVSSGECDTTIKIWQLSTGQLLRTLTGHSDEVNSLAISPDGQTLVSGSDDKTIKIWQLSTGQLLRTLTEHSQRVRSLAISPDGQTLVSASDDDTIKIWRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY02</accession>
    <name>A0A2G4EY02_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_016350</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54413">
        <property type="protein sequence ID" value="PHX54413"/>
        <property type="gene ID" value="CP500_016350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="144"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="356" mass="38735" checksum="0E8D573A3100E3E5" modified="2018-01-31" version="1">MKWWKNLKNNPLAQFGAVLLLIFYTVALLADFVAPYDPYDSQLNGSLLPPTQIHLTAPDGRFIGPHVYPTTQGPVDANTGDRQVIIDSQKPNSLVLFAKGSPYKMFGILPLDRHLFGTVGEAKINILGTDEQARDQFTRLVYGSRISLSIGLVGIAISFPLGLLIGGISGYFGSWIDSVLMRFVEVLMTIPGLYLLVALAAILPPGLTSAQRFILIVIITSFISWTGLARVIRGQVLSIKEREFVQAARAMGANPIYIIVRHVLPQTATYVIISATLSVPSFIVAESVLSLIGLGIQQPDPSWGNLLSLSTNASILVLQPWLVWPPAILIILTVLAFNLLGDGLRDALDPRSADRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY30</accession>
    <name>A0A2G4EY30_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54429">
        <property type="protein sequence ID" value="PHX54429"/>
        <property type="gene ID" value="CP500_016225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="382" mass="43016" checksum="52AF2D1EEEC0B307" modified="2018-01-31" version="1">MKVLVIGGDGYCGWATALYLSNKGHEVGILDSFVRRHWDLELCSDTLTPIAPIQQRLQRWQDLTGKSIDLFVGDITNYDFLSKSMRKFAPEAVVHFGEQRSAPFSMIDREHAVLTQVNNVVGTLNLLYAIREDFPDCHLVKLGTMGEYGTPNIDIEEGYITIEHNGRKDTLPYPKQPGSFYHLSKVHDSHNIHFACKTWGLRATDLNQGVVYGVLTEETGMDELLINRLDYDGVFGTALNRFCIQAAIGHPLTVYGTGGQTRTFLDIRDTVRCVELAIANPAEPGQFRVFNQFTEQFSVGDLAGLVQKAGTAMGLKVEINHLENPRVEKEEHYFNAKNTSLLDLGLQPHYLSDSLLDSLLNFATKYQHRVDKNQILPKVSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY39</accession>
    <name>A0A2G4EY39_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54398">
        <property type="protein sequence ID" value="PHX54398"/>
        <property type="gene ID" value="CP500_016270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="165" mass="18508" checksum="8E169C019647DBC7" modified="2018-01-31" version="1">MKIRDASESDLPAIVQIYNAAIPGRSATADLEPISVESRLPWYRQHSPDSLPIWVMESEQTIIGWLSLQRFYGRAAYQHTAEVSIYITPDRQCCGVGQKLLQQAIGRSPELGIKTLIGIIFAHNQPSLKLFNKFGFQTWGHLPQVAELDGVERDVVIIGLRLNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY47</accession>
    <name>A0A2G4EY47_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EAL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54380">
        <property type="protein sequence ID" value="PHX54380"/>
        <property type="gene ID" value="CP500_016460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="200" mass="21989" checksum="C2AD4CBB45F6ED3F" modified="2018-01-31" version="1">MPNSQFPIPDAPCPMPNFRLPIIDPSALTMSVNLSPKQLGMPNLLEQIDEILAETGCDPSCLKLEITESAIVENVKKANIVLAELKAKKIRLSIDDFGTGYSSLSYLHRFPLDTLKIDRSFVSRLGTSEDGNDGSQHLQIVRAIVTLAHNLGLEAIAEGVETAEQLAQLRELECELAQGYWFSKPLDGNAITEMLKRAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY48</accession>
    <name>A0A2G4EY48_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000100">
        <property type="protein sequence ID" value="PHX54441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54441">
        <property type="protein sequence ID" value="PHX54441"/>
        <property type="gene ID" value="CP500_016040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SH3b" evidence="1">
        <location>
            <begin position="85"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="14514" checksum="768292303A541FA5" modified="2018-01-31" version="1">MEALALSHSFVAYESPESELQLKSLDELGLKIPNSAWIGVASVAIALSVVSIPGEAQAGGCYSSRCGRGHHGHHNYYAQVDTNGGRLNIRHRASRCSSVIGKLYNGDQVALTGRHRHGWAELADGGWVSKKWIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYH4</accession>
    <name>A0A2G4EYH4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative tRNA (cytidine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.207</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (cytidine/uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_015335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could methylate the ribose at the nucleotide 34 wobble position in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43088"/>
            <dbReference type="Rhea" id="RHEA-COMP:10333"/>
            <dbReference type="Rhea" id="RHEA-COMP:10334"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74508"/>
            <dbReference type="ChEBI" id="CHEBI:74511"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43084"/>
            <dbReference type="Rhea" id="RHEA-COMP:10331"/>
            <dbReference type="Rhea" id="RHEA-COMP:10332"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.207" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000090">
        <property type="protein sequence ID" value="PHX54583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54583">
        <property type="protein sequence ID" value="PHX54583"/>
        <property type="gene ID" value="CP500_015335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="tRNA_cyt/urid_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="PTHR42971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029256">
        <property type="entry name" value="SpoU_TrmH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR029256-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="153" mass="16720" checksum="6A8BD02B558405E3" modified="2018-01-31" version="1">MPQLVLIHPQIPPNTGNIARTCAATGTELHLVGPLGFEISDRYLKRAGLDYWPYVKLHCHEDLTAFLDCQQQRGGRSIGFSTGGRCSYTKFQFQPSDWLLFGSETVGIPPLVLDACDATVFIPMSQPGVRSLNLSVSAAVGLFEARRQLGELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYT6</accession>
    <name>A0A2G4EYT6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-antigen ligase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54347">
        <property type="protein sequence ID" value="PHX54347"/>
        <property type="gene ID" value="CP500_016590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="270" mass="30419" checksum="E3D6B80EB36AB3B0" modified="2018-01-31" version="1">MPHAQFLFLTFAVVGNAVCLIFTNSRNAWILAVLAVLAFAVYAGWKKLLAGVFSAVGAVFLSAFGPQPLRQYLRTIIPAFFWARLTDEMFPNRPTATLRTTQWQFAWSMTQQRPWTGWGLRNFTPLYEAQMHEWLGHPHSLVLMLTAETGIPVTLCFLGLVGWILARGVLLLLNWRSHFPVDTQQQEIEENAISNITNRVICQDVNSGDRLIFFSYLLAFAACTLFNTVDVTLFDFRVNTISWLILAAICGIGHRESGIGNRALGIGHWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ27</accession>
    <name>A0A2G4EZ27_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54728">
        <property type="protein sequence ID" value="PHX54728"/>
        <property type="gene ID" value="CP500_014560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="135" mass="14678" checksum="BC053CA5110C8E61" modified="2018-01-31" version="1">MPNEELEPSTPEAPAEAIPSTPEDFAKVLAQTIPQNMAAAMAQLTPEDLAKLLSLLLKAESEQVKDQSELKKQRGNLATWLVGMMAVSLVVFTGFLFTDKKNETSARELITLFWTSQVGLVGGVVGYYFGADSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ70</accession>
    <name>A0A2G4EZ70_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_014245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54778">
        <property type="protein sequence ID" value="PHX54778"/>
        <property type="gene ID" value="CP500_014245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="784"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="491"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="523"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="823" mass="92227" checksum="1B4D71BFAD2E638F" modified="2018-01-31" version="1">MGKLVVLNIVDGDFENGFPVFLEIANDGDYRFAEADGKLPSAPQLLKHYEDWQKPYSSIVSSLRSSRISGTGYTPSSRISEAKTASQKLKLSLNNWLESPEMHSISKSISRNLKDDSEEIRVIIKTKIPELQRLPWHLWNDFFQHYRRAEVALSLPVQKKQRVNTREKTRILAVFGKTEAFGNTTKINTEKDWELLKQHLSDAELIRMVEPSLEELYEQLEEKSPDLFFFAGHSSSEDNSTRGLIELNQDEAITIDDLKPALRQAVEGGLQLAIFNSCDGLGIARELADLHIPQIIVMREPIPDVVAQKFLQRFLEAFVGERSVCLAVRRAREKIHSLEPKFPGVTWLPIVFQNPAELPLTGQDFRRIATGVNSNQANPIYEVPEVGDQSQILWLPTNVGNPYQGQQPPSTVVNKGSGFLITCSHGHQNPVGNRFCIHCGITLKEQETGNGNSSLPVEPPPVWSASQQGNKIIAPRNVGIIAPGSVLAGHYQIIKILGQGGFGETYLAEDLHLPGNPNCVIKKLKPASSSPEILQIARRLFDTEAKILYQLGEHDQIPRLFAHFEENQEFYLVQEFIDGEDLSQEIIPGKQMSESYVIELLRDVLNVLEFVHQHNVIHRDIKPSNLIRRKPDGKLVIIDFGVAKEITNLAANTENQPMTIAIGTQGYFAPEQMRGQPRMNSDIYGLGMIGIQALTGVYPYNLPEDPATGEINWRTQAQVSPKLARILDKMVRSNFRERYESATEVLQDLTSLRRTVLASPSTTQIPSTTKIYNRSVWTNLSIRIYLIVGLIALSFLTALALLTFAPKSLNPDRPSPPPTEDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZA0</accession>
    <name>A0A2G4EZA0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ</fullName>
            <ecNumber evidence="8">4.2.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase</fullName>
            <shortName evidence="8">(3R)-hydroxymyristoyl-ACP dehydrase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Beta-hydroxyacyl-ACP dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">fabZ</name>
        <name evidence="10" type="ORF">CP500_013900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:13097"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="4.2.1.59"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the thioester dehydratase family. FabZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54818">
        <property type="protein sequence ID" value="PHX54818"/>
        <property type="gene ID" value="CP500_013900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00406">
        <property type="entry name" value="FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010084">
        <property type="entry name" value="FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01750">
        <property type="entry name" value="fabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="3 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="173" mass="19340" checksum="7C5CC3B007797921" modified="2018-01-31" version="1">MSTLTEVNTTNHANSESVPTENSQDSAIVKSTFTVEEIQKLLPHRYPFALVDKIIDYVPGVRAVGIKNVTFNEPHFQGHFPGRPIMPGVLIVEAMAQVGGIILVQLPDIEQGLWMFTGIDQVKFRRQVVPGDRLVMTLELLWVKRRRFGKMQAMAEVDGQKACSGELTFSMVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZB1</accession>
    <name>A0A2G4EZB1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54840">
        <property type="protein sequence ID" value="PHX54840"/>
        <property type="gene ID" value="CP500_014020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="7645" checksum="B000A93DD27C6F2B" modified="2018-01-31" version="1">MPFTELVPLLKELSHAEKLLLLHFLVAELLKESGLVPLSDGGTPASQGLHDSFEAASVLARALAEEKVATHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZE7</accession>
    <name>A0A2G4EZE7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54884">
        <property type="protein sequence ID" value="PHX54884"/>
        <property type="gene ID" value="CP500_013695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="269" mass="30529" checksum="61E5D04FEFB3E166" modified="2018-01-31" version="1">MKYAIIGVEGPHDQAFTGKVLKLLGFKDFREEWNKLDKLTRLDMSKELESKFDKFWHKFIPRYPKQGDLYKRLDMPSILFNDTVSVVIYAGEGSNLVINLDDILSNNSEYQTNLSAFGIVTDCDNKSNLNKIVSEYTNKFRNYFPDLPDRAGVVNSNSPRTGIYILPDNASPGVLDTLLCECGEIAYPAYMEKASSYLDRFSESEMQSLKWKNFDREKALVATIVSVLKPGKTNTTSIADNNWVSEKTQQQVPALANFIDFLSQLLEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZG3</accession>
    <name>A0A2G4EZG3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Diacylglycerol kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_013540</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial diacylglycerol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54906">
        <property type="protein sequence ID" value="PHX54906"/>
        <property type="gene ID" value="CP500_013540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14265">
        <property type="entry name" value="UDPK_IM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000829">
        <property type="entry name" value="DAGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036945">
        <property type="entry name" value="DAGK_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033717">
        <property type="entry name" value="UDPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34299">
        <property type="entry name" value="PTHR34299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01219">
        <property type="entry name" value="DAGK_prokar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01069">
        <property type="entry name" value="DAGK_PROKAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX54906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="169" mass="18088" checksum="84AE249926C5E253" modified="2018-01-31" version="1">MTLDQHSKISNIAQLLPMPQDASNQTLNGSKKALKYNRELSWKIASSLAISFKYAWAGLTYAFETQRNFRIHTVIGTLAIGLGIFLHLKPVEISVIGITIGIVLAMELLNTAIESLVDLTVGQSYHELAKIAKDCAAGAVLVSAMASAIVGVALLLPPLLTSVQFAIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZJ0</accession>
    <name>A0A2G4EZJ0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Restriction endonuclease subunit S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_013505</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245954">
        <property type="entry name" value="S.Tbo703ORF13510P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54930">
        <property type="protein sequence ID" value="PHX54930"/>
        <property type="gene ID" value="CP500_013505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="20"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="214"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="407" mass="46521" checksum="737B89F034DDE712" modified="2018-01-31" version="1">MSRKIKKKVPVLRFPEFEGDWHELKFNKLIQLISGQHLSPNEYSLDSGEIPYFTGPSDFTNDLSKITKWTKYSEKSAQQGDILITVKGNGVGEMLFLYLPCVAMGRQLMAIRPITVVGEILYQKLFTYRQQFQALASGNVIPGLSRPDILTTKIYLSGLKEQEKIASFLWAVDTRLTQLRRKHELLQTYKRGVMQKIFSQQIRFKCDDGKAFPDWKEKKLGDLGELLNGLTGKKAEDFGKGKPYITYKQVFDSSYIKLNACEFVSLAPQEKQNSIKRGDILFTTSSETSNEVGFSSVLLHEVEELYLNSFCFGLRPQSSQELIPKFSQYLFRSSIFRGKMYILAQGSTRFNLSKSSFVRVKLPIPCPQEQAKIADFLTAIDQKIEAIAKQIKLTEQFKKGLLQKMFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZJ3</accession>
    <name>A0A2G4EZJ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000072">
        <property type="protein sequence ID" value="PHX54923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54923">
        <property type="protein sequence ID" value="PHX54923"/>
        <property type="gene ID" value="CP500_013470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="185"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="225"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="305"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="362" mass="40325" checksum="2DCE6656610A2BE8" modified="2018-01-31" version="1">MHCQSYHFSYIAAISIVLSPALSVLAISDAWAFAPIINARDFRVGDSLRDSFAARAQATDSKIQADKLFETGVKQYRQGLFREAIQAFEQALAIRQQLGDKPGIGETLNNLGEVYGDMGLQPKALEVLRQALIIHREIGEGPRIARTLNLIGFVNRVADKFSEAMKLHQEALELAKTANDQIEIGESFHNIAAVYGEQGNYAKAIEFYQQARTIRTKNGDRRDLGRTLNNMGGVYYNIGDFNRAMEFYHQALAIRREIGDRAGVGRLLNNMALTSRKLGKDTQALIYFQQAMIMLEAIGDKTSVGRLLNNMGTIYERLGQYGKALESYERALKNARDGGDKVGENTAIEGIRRLSSSQRLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZK5</accession>
    <name>A0A2G4EZK5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54918">
        <property type="protein sequence ID" value="PHX54918"/>
        <property type="gene ID" value="CP500_013605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="224" mass="25429" checksum="A270C830335445E5" modified="2018-01-31" version="1">MFILKRQDVEITNFQHPKRDQQIPILNYQGQTFRLISAFNGKQAEDARALWRDLTDNKGKACVLLEEPDRYSVWGKVRLDQLVGEEPTGTSAAKAPLFAQACLLLLQAVYFDVEDLLGARQAGSFQKDIAKIFQQGSFPMADSPDAIKNWLTVSPLQGHKVPPWQDEHLKTLLQELHRLGKSYFGNTDFAQGVSDVLEDMPAQERNQFIDWLKQSALNKLWISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZP6</accession>
    <name>A0A2G4EZP6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54667">
        <property type="protein sequence ID" value="PHX54667"/>
        <property type="gene ID" value="CP500_014885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="10"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="33343" checksum="E48A8670CBB1B5EF" modified="2018-01-31" version="1">MVNLEPMVFSIIVPTYARPEKLTACLQSFAKLEYPRDRFQVIVVNDSTEISVESIIAPFQNQINLTLLTQPNSGPATARNTGAFAATGEFLVFTDDDCAVAPDWLQTLEARLAKTPHCLIGGRIINALPDNIYSTASQQLIDYLYSYYNAIPDRAKFFTSNNFALPAAAFEKIGGFDTSFGLAAGEDREFCDRWLNSGYTAVYAPEVIVYHSHELSLHKFWQQQFNYGRGAFLFQQITAKSAGKRKLQHPSFYLNLLTYPLSYTPGIQKLLIAGLFFVSQVAISAGLFWEKNIHYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZT1</accession>
    <name>A0A2G4EZT1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Site-2 protease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_013075</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55008">
        <property type="protein sequence ID" value="PHX55008"/>
        <property type="gene ID" value="CP500_013075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044838">
        <property type="entry name" value="EGY1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31412">
        <property type="entry name" value="PTHR31412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="464"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="513"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="9">
        <location>
            <begin position="423"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="125"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="542" mass="58288" checksum="E1CDBF131DF03208" modified="2018-01-31" version="1">MFAATLFDIPRNLMFLFDGSAIDLHKPVLAQATGMETMIASENTATIALLLIAVGILGRGFYRAKPFGKLGILAWLQSVVLMSPWLLFFGLFSAGIYLNLVAVLLMLVASTGLYIYLGRELRSAAGDSAGRSPDTTEVKSVSDRNSAPESPTPPREPVKTLTSSQTNDQSQIIPIPAEDLKAIQGIFGVDTFFATETIPYQDGVILKGNLRGDPEQVHSRLSASLQAKLGDRYRLFLVENQDDKPVAIVLPSENDPQPTTLSQKILAVVLLLATIATTLETSGLLLGFDFLSAPTRYSEVLPIATGIWAVLGSREIARRVLASQYNVRLSWPFFIPTWQIGSFGAIDRFESLLPNRKVLFDISIAGEATGGIIALSMLIVGLLLSHPGSLFQIPAELFKASLLVGTLSKVILGSALQQPLVDVHPLVVIGWLGLVITAINLMPAGQLDGGRIVQAIYGRKTANLATLATFAVLAIASLVNPLALYWAIVILILQRNLERPTLNELTEPDDARAALGLLALFLMIAILLPLTPVLAGRLGIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZY5</accession>
    <name>A0A2G4EZY5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="5">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ppa</name>
        <name evidence="6" type="ORF">CP500_012910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000067">
        <property type="protein sequence ID" value="PHX55058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55058">
        <property type="protein sequence ID" value="PHX55058"/>
        <property type="gene ID" value="CP500_012910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00209">
        <property type="entry name" value="Inorganic_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="19110" checksum="441A39DF9C996E0B" modified="2018-01-31" version="1">MDLSLIPAQPKPGLLNVLIEITAGSKNKYEFDKELQAFALDRVLSSSVQYPCDYGFIPNTLADDGDPLDGMVMMDEPTFPGCVILARPIGMLEMIDGGDRDEKLLCVPDKDPRYAHYKSLKDVAPHRLDEIAEFFRSYKNLEKKVTEILGWQDVDKVMALVEQCIAADRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F063</accession>
    <name>A0A2G4F063_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Urease subunit alpha</fullName>
            <ecNumber evidence="5">3.5.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Urea amidohydrolase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 14" type="primary">ureC</name>
        <name evidence="14" type="ORF">CP500_012230</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 10">
            <text>2 H(+) + H2O + urea = CO2 + 2 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20557"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7 10">
            <name>Ni cation</name>
            <dbReference type="ChEBI" id="CHEBI:25516"/>
        </cofactor>
        <text evidence="5 7 10">Binds 2 nickel ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Carbamylation allows a single lysine to coordinate two nickel ions.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Carboxylation allows a single lysine to coordinate two nickel ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.5" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55145">
        <property type="protein sequence ID" value="PHX55145"/>
        <property type="gene ID" value="CP500_012230"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00258">
        <property type="reaction ID" value="UER00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00375">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01953">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011612">
        <property type="entry name" value="Urease_alpha_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017950">
        <property type="entry name" value="Urease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005848">
        <property type="entry name" value="Urease_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017951">
        <property type="entry name" value="Urease_asu_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029754">
        <property type="entry name" value="Urease_Ni-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00449">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01752">
        <property type="entry name" value="UREASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01792">
        <property type="entry name" value="urease_alph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01120">
        <property type="entry name" value="UREASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00145">
        <property type="entry name" value="UREASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51368">
        <property type="entry name" value="UREASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 7" id="KW-0533">Nickel</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urease" evidence="13">
        <location>
            <begin position="131"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5 8 9">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="5 7">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="5 6">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX55145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="585" mass="63164" checksum="8A820F5020A84AFB" modified="2018-01-31" version="1">MSYRMDRRAYAETFGPTVGDRVRLADTELFIEVEQDFTIYGDEVKFGGGKVIRDGMGQSPISNADGAVDTVITNALILDWWGIVKADVGIKDGKIYKIGKAGNPYIQDRVDIIIGPGTEVIAGEGMILTAGGIDTHIHFICPQQIEVAIASGITTMIGGGTGPATGTNATTCTPGPWHMYRMLQAADAFPVNLGFLGKGNTSQPQALVEQILAGAMGLKLHEDWGTTPATIDTCLNVADEYDVQVAIHTDTLNEAGFVEATIAAFKNRAIHTYHTEGAGGGHAPDIIKVCGQANVLPSSTNPTRPYTVNTLEEHLDMLMVCHHLDRSIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVIIRTWQTAHKMKVQRGILHGQDARSTGDLDGQDARSTGGENDNFRAKRYIAKYTINPAITHGISQYVGSIEEGKLADLCLWRPAFFGVKPEMVIKGGAIAYSQMGDANASIPTPQPVHMRPMFGSFGGAIGATCLTFVSQAACDRNIATQLGLQKPTVAVSGTRQITKRDMKLNDYLPTMEVDPETYEVRADGELLICEPATVLPMAQRYFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F089</accession>
    <name>A0A2G4F089_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polynucleotide kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55184">
        <property type="protein sequence ID" value="PHX55184"/>
        <property type="gene ID" value="CP500_012265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="282" mass="32537" checksum="4620542EF575A843" modified="2018-01-31" version="1">MKRVIVLVGLPASGKSQFARELLLSEPARWVRTNKDLLREMAHASHWSPANEKFIVELRDRIILMALESGKHVIVDDTNFGPHIEHIKELVKGQAVVEVNDSFLQVPVEECIKRDLKRLNSVGKDVIMKMYNRYVRVPVSPPEYNPDLPDAIIVDMDGTLSLLNGRNPFDASKCDRDLPNQPVLDTIRKWQSSVNIIVVSGRTDDCQPQTEKWLQQYEVNYTAIHLRKTGDMRKDAIMKEEIYRQHIEGKYNIKFVLDDRQQVVDMWRSLGLTVFQVDEGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F156</accession>
    <name>A0A2G4F156_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55483">
        <property type="protein sequence ID" value="PHX55483"/>
        <property type="gene ID" value="CP500_010585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013881974" evidence="2">
        <location>
            <begin position="28"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="184" mass="19654" checksum="834B57222B9F8BEE" modified="2018-01-31" version="1">MKLSSARRILAPFLISVLLLVTSCGKAPEPSRWDKAQQESTQKPGKANQNKTDQSSAQNQNLPKKAVAGGKLNKYFPSSGDGFDRVFAQEKSGFAEAKLNKGGKNVAMLSINDIAGNPKAGDKFQSSTKQIGGYPAVTQGANGTAVLVANRYQVKVQSRDASFSASDREDWLSKFNLSGLASVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1D0</accession>
    <name>A0A2G4F1D0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1016 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55556">
        <property type="protein sequence ID" value="PHX55556"/>
        <property type="gene ID" value="CP500_010245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009362">
        <property type="entry name" value="YhcG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041527">
        <property type="entry name" value="YhcG_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17761">
        <property type="entry name" value="DUF1016_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06250">
        <property type="entry name" value="YhcG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1016_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="YhcG_C" evidence="1">
        <location>
            <begin position="174"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="347" mass="40592" checksum="534229790445E840" modified="2018-01-31" version="1">MANNLSIPEDYHDFLRELKGRILQSQVRAVLSVNRELVLLYWQIGRDILNRQQQQGWGTKVIDNLATDLRTAFPEMKGFSSRNLKYMRSFAETYPDEQFVQEVLAQITWYHNIALMEKLKSSEERLWYARQTIEQGWSRNVLVHQIESGLYRRQGKADTNFSRTLPNPQSELAQQLLKDPYNFDFISLSQEAQERELEKALIDRIRDFLLELGVGFAFVGSQYHLEVEGEDFYIDLLFYHLHLRCFVVIDLKVEAFKPEFSGKMSFYVSAVDDLLKHRDDMPTIGMILCKNKKQKIVEYALRDLNKPIGISTYQLREALPEQLQGSLPTVEQLEAELEAVEIEIEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1G7</accession>
    <name>A0A2G4F1G7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polyamine aminopropyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Putrescine aminopropyltransferase</fullName>
            <shortName evidence="3">PAPT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Spermidine synthase</fullName>
            <shortName evidence="3">SPDS</shortName>
            <shortName evidence="3">SPDSY</shortName>
            <ecNumber evidence="3">2.5.1.16</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">speE</name>
        <name evidence="6" type="ORF">CP500_009765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>putrescine + S-adenosyl 3-(methylsulfanyl)propylamine = H(+) + S-methyl-5'-thioadenosine + spermidine</text>
            <dbReference type="Rhea" id="RHEA:12721"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="2.5.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer or homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55611">
        <property type="protein sequence ID" value="PHX55611"/>
        <property type="gene ID" value="CP500_009765"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00248">
        <property type="reaction ID" value="UER00314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="1 3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="5">
        <location>
            <begin position="9"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-methyl-5'-thioadenosine binding" evidence="3">
        <location>
            <begin position="145"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="34943" checksum="7708AFD5DA307B5B" modified="2018-01-31" version="1">MSGSEVRADFWMSEYITPWDIYVHGITRVLAYKKTAFQEMYVVETGIYGKGLVLDGKWQSCTGDEFLYHEPLVHPAMTLHGSPKKVLVLGGGEGATIREVLRWNSVEKVVMVDIDGEVVDACREHLPEMHQNAFDDPRCEVVIGDALDYLDNSDSDWDIVISDLSDPIEEGPSFQLFTKEYFEKVRRVLSPTGYFVVQAGPVSPAEMKMHARIVNTLKSVFPKVQSCTSFISTYGAPWGFAVASTQEINTRPEPEVTDKLLAEQTIGGFRMFDGITLLGLMQVAGHLRKVIATETEVYTMAAPPKFFGKGSVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1K2</accession>
    <name>A0A2G4F1K2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55347">
        <property type="protein sequence ID" value="PHX55347"/>
        <property type="gene ID" value="CP500_011145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="205" mass="19542" checksum="AD975489CB4C4B34" modified="2018-01-31" version="1">MSSLPPAAAGKPILGLSGNDNITGTSGFDIINGMQGADTIDGGAGNDSLTGGKGSDQIEGGAGNDNLSGNNDNDTLTGGDGNDTITGGKENDVLIGGLGDDILSGDRGQDILTGGGGSDTFILTGGAATAATLAEADVIADFTVGDKIGLTGGSVFASLTLEAVSLNLNGGAAVSATAIKLGGYLGIVVGVAPSELTASVFVPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1L5</accession>
    <name>A0A2G4F1L5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55646">
        <property type="protein sequence ID" value="PHX55646"/>
        <property type="gene ID" value="CP500_009545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="293" mass="33591" checksum="E8F16F3A48A108FB" modified="2018-01-31" version="1">MTFINPKTDYAFKKIFASQDSKGILISFLNATIYDGNPTITDLEIIDPNLPPKIAGLKDSSLDVKAQLTDGTLIIIEMQVLNVESFGKRVLYNAAKTYASQLQKGQGYRMLKPVIALTITDFEMFENSDRLISRFVYKETTTNIEYFDNHIELVFVELPKFTKELSQIETLTDKWIYFMKYANMLTQVPQTMDVVPEIHQAFDIANQVNLNPGELEALERQELFIYDQQGIIIKANREGREEGREEGREEGREEAMQAVARQLLDRLDNETISQTTGLSIEEIRNLRSERTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1M4</accession>
    <name>A0A2G4F1M4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55648">
        <property type="protein sequence ID" value="PHX55648"/>
        <property type="gene ID" value="CP500_009555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="20484" checksum="71022AD8AFEEE227" modified="2018-01-31" version="1">MTESRNLNFSNQNLRNRSFKGRDLSGANFSGSDIRGCNFTGAILRGANFQGARMGQSRRRVRTLIARAGVTAVSVTLAGALMGLIGGADAGAAAVVAVAATAIAATRAEAGIVAGAVAGAAAAIGASGIVTFFGGDAIRGIVLFLVSGVMLGLTAIGFFIAVEEIEKLSVTSFRKADVTDAIFEESAMLNADFSDARGCDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1N2</accession>
    <name>A0A2G4F1N2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55674">
        <property type="protein sequence ID" value="PHX55674"/>
        <property type="gene ID" value="CP500_009710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7753" checksum="AB42A780D7D036EB" modified="2018-01-31" version="1">MLLKLGWYFEAFVYFNAMTIAEICLGNYQKNRKGRSQLPRKALSKSKKPEVRTKKENWSQFPRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1W0</accession>
    <name>A0A2G4F1W0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000042">
        <property type="protein sequence ID" value="PHX55750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55750">
        <property type="protein sequence ID" value="PHX55750"/>
        <property type="gene ID" value="CP500_009085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="8946" checksum="048E0F574F356F47" modified="2018-01-31" version="1">MTLANYQLSLNFEQILALVKQLPYPEKLQLSQELEKEVLNSKLTVLLESFRTDELSLETIAQEVEAVRSEIHATKTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Z8</accession>
    <name>A0A2G4F1Z8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3352 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55776">
        <property type="protein sequence ID" value="PHX55776"/>
        <property type="gene ID" value="CP500_009060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021787">
        <property type="entry name" value="DUF3352"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11832">
        <property type="entry name" value="DUF3352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="590" mass="63931" checksum="AD6896E458286196" modified="2018-01-31" version="1">MFKKDKSSLLFTIGAATLLIGLGFITYSIVISRGSGKDLPVGATVVPQDTMMAISISTDASQWKRLREFGTTESKASFERLLTELGDRILTSNGYGYQQDIQPWVGDRAMVAFLRNKIAIPVPPSDPNAPPPPPIQQSVAIILPIANPIKAKELLAKPRPLNQGKMVERNYKGVQVTETQGIPDRNFSVAILGTNYLAISTDPTATDRIIDTYKGEPSLAKTPGYENAIEKIKSPGAFGQVYVNMPVAAAFTAANSAREFSPESLEKLQQNQGFATTVTLDTEGIEFKSISWLKPDSQKRIPVENNAEKMANRLPNNTIMMVSGGNLRRLWEDYVSGADANPIAPVNPQILRTALKSTTGMDLDKDLIDWMAGEFSLSLIPAIAPNPKDKFAAGFVFMVETNNRGGADKALKLLDDTMKTKGFRVEEIKVGGQGATKWTSPFGGITVTRGWMKNVLFLTVGAPVIDAIVPAPKSPLFGSELFQKTVRSKLKPHNGNFFIDTESVFNPKNLTLPEFLTSNQKIWIDAIRSIGITAAVIGDRTTRYDAFVNLKKSEQSSPSSNPSPNPLSPSSSSPTPSDATPTSPSPSPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F217</accession>
    <name>A0A2G4F217_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55785">
        <property type="protein sequence ID" value="PHX55785"/>
        <property type="gene ID" value="CP500_008840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8463" checksum="3ACB3ACE16549023" modified="2018-01-31" version="1">MTLHELQDRALRLSAQERWQLINALMRSLQPKPRSKVKPKGLAASLIGIAKTDSPPPTDAEVKAMLDERLVQKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F288</accession>
    <name>A0A2G4F288_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55858">
        <property type="protein sequence ID" value="PHX55858"/>
        <property type="gene ID" value="CP500_008470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="193" mass="22159" checksum="1D333D66A3C84823" modified="2018-01-31" version="1">MSDIAILKEMIQESATVPLEEHKGKKQVILKEPPPADYSVTIDGMPDDAQVIVIKADAFPAPSKIFTSSKGQCKRADFVIIADTPTEKIIFCIEMKKKKEQNTKIIQQLTGAKCFVDYCKEIGKAFWHQQNFLDAYEYRFVSIGHISIPKVKTRNNRSTETNDRLNEIHDRPDRMLKISRLNKIQFNRLIYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2L2</accession>
    <name>A0A2G4F2L2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NYN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56014">
        <property type="protein sequence ID" value="PHX56014"/>
        <property type="gene ID" value="CP500_007610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="19"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="169" mass="19396" checksum="6528EED86BA937B5" modified="2018-01-31" version="1">MTDNHLVIGKQISQQQSLVSIYWDYQNIPDKKLANNLLLLGNSLGYVVNKKAYDYWEKDHKVYQENKRTLVNLGWECVNVFQTIKNAADFSLLFDCSGEAAISPYSHTFIIGSGDGYNEILIPKLQDKGKKVIIVARRDSENKNLERLANEFYFLDELPKLLESYKLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2L8</accession>
    <name>A0A2G4F2L8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 15">NAD(P) transhydrogenase subunit beta</fullName>
            <ecNumber evidence="6 15">7.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Nicotinamide nucleotide transhydrogenase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CP500_007540</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 15">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the PNT beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="6 15"/>
    <dbReference type="EMBL" id="NXIB02000033">
        <property type="protein sequence ID" value="PHX56000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56000">
        <property type="protein sequence ID" value="PHX56000"/>
        <property type="gene ID" value="CP500_007540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:NAD(P)+ transhydrogenase (AB-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012136">
        <property type="entry name" value="NADH_DH_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000204">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="11 15" id="KW-0521">NADP</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 15" id="KW-1278">Translocase</keyword>
    <keyword evidence="10 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="PNTB" evidence="17">
        <location>
            <begin position="10"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="PHX56000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="468" mass="48554" checksum="68D18BB9EA08BDFF" modified="2018-01-31" version="1">MSDFLPSAIQLGYLVAASLFIVGLKQLGSPATARQGNVLAAIGMLIAIVGTLLEKQVISYELIAVGIIIGSILGTIMANTVAMTDMPQMVGLLNGFGGAASALVAVGEFWRYLSIPESPTPDATITILLGVLIGGITFTGSLVAFAKLQELLPGAPMTFPLQQPFNAALAIALLAGSGYMLANPENVPVFLGLVAISNILGIMFVLPIGGGDMPVVVSLLNSYSGIAASVAGFILMNNMLIIAGALVGASGIILTQIMCKAMNRSLSSVLFSAFGSGGSAATAGAAGAAIDKTVHSIDIEESAMMLGYARSVVIIPGYGMAVAQAQHAVRELADGLEKMGVDVKYAIHPVAGRMPGHMNVLLAEANVPYPQLYDMDDINPQFDETDVALVIGANDVVNPAARHDTASPIYGMPILEVDKAKHTIVIKRGMSAGFSGVDNELFYKDKTMMLFGSAKDVVAKLVAEVKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2X1</accession>
    <name>A0A2G4F2X1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YiaAB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56100">
        <property type="protein sequence ID" value="PHX56100"/>
        <property type="gene ID" value="CP500_007280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008024">
        <property type="entry name" value="YiaAB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05360">
        <property type="entry name" value="YiaAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="YiaAB" evidence="2">
        <location>
            <begin position="14"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="93" mass="10478" checksum="5A4B06EA61BB314D" modified="2018-01-31" version="1">MQQQIGRQKDTNAWILQCWISFILAISTTAVGVIYLPVDIWVKSFMGMGLTFSVGSSFTLAKTIRDNNEATRLTARIDEARVEKILADHHPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F324</accession>
    <name>A0A2G4F324_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5678 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56146">
        <property type="protein sequence ID" value="PHX56146"/>
        <property type="gene ID" value="CP500_007080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043734">
        <property type="entry name" value="DUF5678"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18929">
        <property type="entry name" value="DUF5678"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5678" evidence="1">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9705" checksum="9395128AF2CEFD5F" modified="2018-01-31" version="1">MEAEYTTAEEWYKANRRELKKKYRGQWIAYTNKGVISCDRDYRKMKDGIPADTPNLSYVIDRIFESEFIEPVRFPGFHCCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F348</accession>
    <name>A0A2G4F348_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system PemK/MazF family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56168">
        <property type="protein sequence ID" value="PHX56168"/>
        <property type="gene ID" value="CP500_006910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="118" mass="12877" checksum="2AA4B6957E3957F4" modified="2018-01-31" version="1">MKPGDIVLIRFPQADLKQGKLRPALVIAIAPGRHPDLLLALVSSRIDQSTAGFDEIIHLVDPDYIATGLKVTSVVRLGRLASVQSSVVNACLGSISNERLIQIKNRLIDWLQNSLQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F374</accession>
    <name>A0A2G4F374_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2358 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56224">
        <property type="protein sequence ID" value="PHX56224"/>
        <property type="gene ID" value="CP500_006575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10184">
        <property type="entry name" value="DUF2358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="15243" checksum="95A5C669091C6C2A" modified="2018-01-31" version="1">MDIIEILKDDYQRFPENQTYSIYAKDVYFEDPVNRFTGVDRYRKMIGFMGTFFQDINLDLHDISQSGDSIDTRWTLSWTAPLPWRPKMAISGRSELKVSPDGLIVSHIDYWDCSRLDVLKQLVFPVKTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F375</accession>
    <name>A0A2G4F375_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56212">
        <property type="protein sequence ID" value="PHX56212"/>
        <property type="gene ID" value="CP500_006505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7264" checksum="69FD564B740C9C69" modified="2018-01-31" version="1">MEQASCLFLTGFLGDVYYLLDVDCTGFVLVDNFTGYFVPQFPILLNSILINPGAQPLYLLKLNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3A1</accession>
    <name>A0A2G4F3A1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56254">
        <property type="protein sequence ID" value="PHX56254"/>
        <property type="gene ID" value="CP500_006445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipase_3" evidence="1">
        <location>
            <begin position="113"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="302" mass="33210" checksum="FCF26065CD4480EE" modified="2018-01-31" version="1">MIQCSKLATQQYLKGKIDPSYNGDIKSLPAYTAKFKGYTQVTAIKGVEAKISEQVEVDIAQSPTSPNSATDPIGDNVGNAQKAIENTAKEVVKIKKKIPVYFGFVLSSKNHNIIVFRGTQRTIEWVLNINAVYATNDRKVASQSYGAIHPGFSAIYSNISSQTLEVAKKLNPSVPCYISGHSLGAAIATLAAIDIAVNIPRLQKQVQLYTYASPRVGDRVFAREHNRVVPNSYRVVNLADAITLVPFTVFFKTEYVHVGEEWAFLAQNGDVMPNHVVDTYKSAIDKQAETNKPRNYPNSGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3C1</accession>
    <name>A0A2G4F3C1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide pyruvyl transferase CsaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">csaB</name>
        <name evidence="2" type="ORF">CP500_006460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56246">
        <property type="protein sequence ID" value="PHX56246"/>
        <property type="gene ID" value="CP500_006460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019896">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase_CsaB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03609">
        <property type="entry name" value="S_layer_CsaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PS_pyruv_trans" evidence="1">
        <location>
            <begin position="13"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="347" mass="38295" checksum="BB75E581366E5B49" modified="2018-01-31" version="1">MRAILCGYYGKGNGGDEALLASLLQMLPDGVTPIVLSGNPVETNQRYGVVARDRMNPFQVLEALRTSDALIWGGGSLIQDATSMISPFYYGGLMGLAQQMGLKTIAWAQGIGPLNRDITRKLSQRCFAGCSAVSVRDKGSATLLTDWEIPFTLAPDPVWALENSPVSGLWDLPAPRVAVCLRSHSTLTPARLSILTQALVDFQKATRTLILLLPFQASHDLEIAKHLHEALPQRSRILSLDDPRKLKGVFRGVEMAIGMRYHSLIMAASEECRCFALSYDPKVSQLMDELEMPGYLLSELPDDPYLISKTWIEHYANGDGLSPERIKFIVGRSLFHQEVLRVALQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3J4</accession>
    <name>A0A2G4F3J4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56354">
        <property type="protein sequence ID" value="PHX56354"/>
        <property type="gene ID" value="CP500_005790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017601">
        <property type="entry name" value="DGQHR-contain_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017642">
        <property type="entry name" value="DNA_S_mod_DndB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14072">
        <property type="entry name" value="DndB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03187">
        <property type="entry name" value="DGQHR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="530" mass="59861" checksum="BF6975E10B60F1C2" modified="2018-01-31" version="1">MNTQPADDLATKILEKENSDRQEIALLLDNYLGKDDRIFVQKTQMGNSEAYIGSVTLEWLDSRVRFASQMPLFRQKFDLQTNNIVRDDETIDEIIQRPLDWSRQAALTQYLAARKSHKFPAVLVVVSPPWVDNPLAEEWDKNGVATKSAAEFTSFDKNQNLGLLNVSKEVSIFALDGQHRLMGVQGLMSLIKTGILQRYNKNKKAVGAAITLEDLAEEYQINPNEVHNLAHEKIGIEFIPAAVAGETRQQAQRRVRSIFVHVNLMAVTLSQGQLALLNEDNGFAICARKIAVTHPLLKEQDDRNPRVNWDSATVAAKSTVLTTLQALQDMSERYLEYKFPHWKPERKGLIPMRPEDEELKEGIEEFKKLFDHLATLPSYQRIESGEETAELRRFSFEKPGGEGNILFRPVGQVALANALGILTFRKKLSLKSTFDKLRRYDVDEGFSHMDNPQSAWYGILYDPNKKRMLVSGKDLAAKLIVYLVAGIGDDMDRAHLRQAVAQARTFEGKAISFNGKFVQPKEVGLPPVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3N4</accession>
    <name>A0A2G4F3N4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BrnT family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56394">
        <property type="protein sequence ID" value="PHX56394"/>
        <property type="gene ID" value="CP500_005635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038573">
        <property type="entry name" value="BrnT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007460">
        <property type="entry name" value="BrnT_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04365">
        <property type="entry name" value="BrnT_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="11982" checksum="F0A9573AD136982C" modified="2018-01-31" version="1">MDYNFDWNIAKEKQNIRKHQLNFRLASTIFRDPYQLTIYDEEHSQDEDRWITIGLDETGIFRLVVHTFEQTDSSSCIIRIISARKATFTETQYYQERKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Y3</accession>
    <name>A0A2G4F3Y3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tellurite resistance protein TerB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56456">
        <property type="protein sequence ID" value="PHX56456"/>
        <property type="gene ID" value="CP500_005500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007791">
        <property type="entry name" value="DjlA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05099">
        <property type="entry name" value="TerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TerB" evidence="1">
        <location>
            <begin position="22"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="16291" checksum="2B67CC0016E09973" modified="2018-01-31" version="1">MGLFDKISQTRQQGEVTLGPAEAFAAIALIAVAADGYINESESQVLNLTLSRMQLFRSYPDDVMKKMLDRLLMLLQRQGVQVLFNAALATLPDELKETVFAVTTDIALADGEISEEEEQLLNDLYSALGLSEEIALKIIDVMLIKNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Z2</accession>
    <name>A0A2G4F3Z2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF815 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56455">
        <property type="protein sequence ID" value="PHX56455"/>
        <property type="gene ID" value="CP500_005495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008533">
        <property type="entry name" value="DUF815"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05673">
        <property type="entry name" value="DUF815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="230"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="434" mass="49226" checksum="AEF1253ED3E81EC2" modified="2018-01-31" version="1">MSTLTSGAIAQIRYLQRQTASLLLYQSVFKSPAGQAFLDLLHALHHSDISGSDCLTAYGNWFKIQAAQNLSWKDFLVSQILKDENPFSRKAQQTDFASLSPALVEAVRHDLQVLQNLYQCSSEQLSKWVRVAGQLEAVPPIWHSETLKENEDLPLHKELENWSSAAESLAAYYGKFGTGLFAEYRAFQWRNGQLASISHPDRINLQELVCCDWQRDALVKNTEFLLAGYPALHVLLYGSRGSGKSSLVKSLLNEYGTRNLRLIEVSKSNLQDLPLIVEQLRGVPQKFIIFVDDLSFEEDDDAFKSLKVVLEGNVTAKAQNVVVYATSNRRHLIREFFDDRPRPRDGDEVHAWDTVQEKLSFSDRFGLTLTFEPADQNTYLTIVRHLALLAGIKIATEDLEYRAKEWATRRNGRSGRTARQFVDFLKAELALSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F424</accession>
    <name>A0A2G4F424_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56496">
        <property type="protein sequence ID" value="PHX56496"/>
        <property type="gene ID" value="CP500_005140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019365">
        <property type="term" value="P:pyridine nucleotide salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044717">
        <property type="entry name" value="NIC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47297">
        <property type="entry name" value="PTHR47297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="26822" checksum="CE9F2A1EF3CB0911" modified="2018-01-31" version="1">MSTTLTRLNSTLAAIETALPIDPQPYAVGERPTGLIVVDVVNGFCTVGYGFCAPSAPDEQIATMVSESDRLARSFVERGWPVLAFLDTHEPGKPEPPYLPHCEKGTGEEKLVSELEWLENHPLATLVAKDCINGFIGSIDRDTGRNILLDWISDRQLEVLVVVGICTDICVMDFVITMLSVRNHGLSPTLKDVVVYAKGCATHNLTAEMAVQQGLTKTTIHPQKIAHHVGLYTMAERGALIASTISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F451</accession>
    <name>A0A2G4F451_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56564">
        <property type="protein sequence ID" value="PHX56564"/>
        <property type="gene ID" value="CP500_004775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="193"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="386" mass="43120" checksum="52FBA59678767195" modified="2018-01-31" version="1">MEKLKILVVNNLYPPQVVGGYERAIADYAKLLQERGHQVLVITSNTEHLPTGYKKADSDPQTVRRCLSLWGSWTELGAQPFYPAHVAAIAVQNYKTLEEVLRSFQPDVCLTGNADFLGSSILEQILAAGIPIAHYVMNSQPGYSYDLAPHSSLYRYITVSNWIRENLQKQGYPTETALTIYPGAEVEEFYQAELTPRDRLRIVYAGLVMHYKGPDVLIEALYLLHEAGVDFTATIAGGSLTPEFARVLQEFVESEGLEEKICFTGLLSRHELVQLYRTHNVWVLPSRFEEPFSIGLIEAMVAGLTIITSDRGGSPEAVQHSKTGLIFESENPLDLADNLSSLPMNPAEWEAITRRGQQRALSELSRTRTMDQLESVLSEMAVQDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F486</accession>
    <name>A0A2G4F486_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56559">
        <property type="protein sequence ID" value="PHX56559"/>
        <property type="gene ID" value="CP500_004740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="20"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="22305" checksum="BE28620CEF8BF3D2" modified="2018-01-31" version="1">MTTTLEQKLDRPLLFPGLTWEQFKTLESMLDIPGVRLSFLDGVLEIEKMPGRKHETAKGRIGALLELYMMAAEIDFTPTESLTLENESRMVKREADKSYELGADRERPDLAIEVVVTSGGIDKLEAYKRLKIREVWFWEKSQLSLYALREEGYEQIASSELLPELDMALFVRCMNIQNHVEAVKEFRSGCDRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4C7</accession>
    <name>A0A2G4F4C7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gap</name>
        <name evidence="10" type="ORF">CP500_004480</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56599">
        <property type="protein sequence ID" value="PHX56599"/>
        <property type="gene ID" value="CP500_004480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="PTHR10836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="4"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="154"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="214"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="343" mass="36737" checksum="79D3B7287D77CB42" modified="2018-01-31" version="1">MATLKVGINGFGRIGRLVMRAGIKNPNIEFVGINDLVPPDNLAYLFKYDSTHGIYDGEVEATADGIIVDGKFIPCTSIRNPAELPWAKCGADYVVESTGLFTDFAGASKHLTAGAKRVILSAPTKDPEKVATYLVGVNHHKFDPAKDTVVSNASCTTNCLAPIAKVINDNFGLEEGLMTTVHAMTATQPTVDGPSIKDWRGGRGAGQNIIPSSTGAAKAVTLVLPELKGKLTGMAFRVPTPDVSVVDLTFKTAQETSYKEICEAMKKASEGELKGILGYTEDAVVSTDFQGDARSSIFDAGAGIELNSKFFKVVSWYDNEWGYSNRVIDLMLSMAQKDGILNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4G2</accession>
    <name>A0A2G4F4G2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_004310</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56639">
        <property type="protein sequence ID" value="PHX56639"/>
        <property type="gene ID" value="CP500_004310"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022163">
        <property type="entry name" value="GTP_CH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12471">
        <property type="entry name" value="GTP_CH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="GTP_CH_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="GTP_cyclohydro2" evidence="6">
        <location>
            <begin position="223"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="415" mass="45331" checksum="2978CB1B4C662D41" modified="2018-01-31" version="1">MSKPKPIVLRSQPDKSATKHLPIDWGEIDPLKRGPVIGSLSKLSHRNAIGTHSGSYSVYRALAVANGTLQADHLPDLTNTSPAEHIGPHPSWGDANLIVSLDPFGALVSEIYSSFYQQGYDIRPTIAVTKAHINLPEIQDAIAHKRVLIDGKIVKSGGNLVVTKIAIDPVWYLPGIANRIGVEESVLRRVLFQQTGGMFSDLVRRPDLQVFLPPIGGTTVYIIGDVAHISDPEKQLAVRVHDECNGSDVFGSDICTCRPYLVHGIEICIQTAQAGGSGVILYFRKEGRALGEVTKFLVYNARKRQPGGDRADAYFTRTECVAGVQDMRFQELMPDVLHWLGISRIDRLVSMSDQKYNAIINSGIQVCDRIPIPEDRIPADAQVEIIAKKAAGYYTPDGVPDATILGETQGRDLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4H0</accession>
    <name>A0A2G4F4H0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L,D-transpeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_004100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56683">
        <property type="protein sequence ID" value="PHX56683"/>
        <property type="gene ID" value="CP500_004100"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013545375" evidence="3">
        <location>
            <begin position="25"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="4">
        <location>
            <begin position="84"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="208" mass="23025" checksum="F4EB84B0C3A3B278" modified="2018-01-31" version="1">MHHRFLNSKSLLGKLILLSLSAAALSVAEPMANFNHSAIAAQSVTSEQKLPNLGAPELPPLGEPFRYIPQEPKPAVNPIEEVRLVLKLRERRVYVYRQNKVQVSFRVAVGKGGWETPTGNFKVTHMIKDPVWEHPWTGELVPAGPDNPLGTRWIGFWTDGKNVIGFHGTPNPESIGRAASHGCVRMFDKDAQALFEKVEVGTPVIVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4K8</accession>
    <name>A0A2G4F4K8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cob(I)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cobO</name>
        <name evidence="3" type="ORF">CP500_003620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56714">
        <property type="protein sequence ID" value="PHX56714"/>
        <property type="gene ID" value="CP500_003620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00561">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025826">
        <property type="entry name" value="Co_AT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12557">
        <property type="entry name" value="Co_AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00708">
        <property type="entry name" value="cobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Co_AT_N" evidence="2">
        <location>
            <begin position="10"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="211" mass="23660" checksum="E9EBFD2EE33F0759" modified="2018-01-31" version="1">MEINTETTTTTGLTAEQHKQKMQRRQEVQSERIANSSKEKGLVIVNTGNGKGKTTAALGMVVRSLGHGYRVAIVQFIKGAWEPAEKAVFQMWENQLEFHAMGEGFTWDTQDRDRDIETAQKAWDKALTFICNPEFRLVLLDEVNIALKLGYLQSEQVLAGLEQKPEATHVILTGRGAPPALIERADLVTEMNLVKHPFREQGIKAQPGIEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4P7</accession>
    <name>A0A2G4F4P7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4351 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56467">
        <property type="protein sequence ID" value="PHX56467"/>
        <property type="gene ID" value="CP500_005480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="24"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="87" mass="9840" checksum="4CBF2981451819B5" modified="2018-01-31" version="1">MRESVIYQEIRSDGLLEGRQLGLEEGRKNEALLLVTRVLTRRIGPIAPPIQEQIQTLSVEELEDLGEALLDFSSASDLTNWLNEHQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4S1</accession>
    <name>A0A2G4F4S1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ubiquinone biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56746">
        <property type="protein sequence ID" value="PHX56746"/>
        <property type="gene ID" value="CP500_003810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007715">
        <property type="entry name" value="Coq4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12922">
        <property type="entry name" value="PTHR12922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05019">
        <property type="entry name" value="Coq4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="231" mass="25806" checksum="20AA57FB62626CEC" modified="2018-01-31" version="1">MKLMDAFKANQPFVAENQQHNHFQMLLIFKSFFAMLAGDESLESVGEMSDALVETPAFDLAAQHLNRDPACAVLIRDRYIPPAHDLNKLLTYPQNSLGYIYATTMKQAGFDPNLHTGMTAESDAKYVELRLSQTHDIWHIVTGFDTSVIGEIGLQAFHLPQLPYPLATMLVANSLMSSTLLAPEELPHLLDAIAQGLQMGKTAKALFAQKWEEAWDKPLAQWQAELNIQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4T2</accession>
    <name>A0A2G4F4T2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_003885</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56760">
        <property type="protein sequence ID" value="PHX56760"/>
        <property type="gene ID" value="CP500_003885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="Uma2" evidence="4">
        <location>
            <begin position="67"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="18119" checksum="6F6903E4E2781F03" modified="2018-01-31" version="1">MGTLVIGKNAQWKNELDLGRKTNQSFVNIPHARLIEMLKYKAELMGIKIVEVSTQADKSFCFGKPKLIPYLSIEVVYTSGGLTKLPKYRALGVPEIWFWEDGILRLYHLREDKYEEVIQSQLSGLETLDIDLLRRCILMGETNLAEAVKVFGQGISTVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4T8</accession>
    <name>A0A2G4F4T8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56758">
        <property type="protein sequence ID" value="PHX56758"/>
        <property type="gene ID" value="CP500_003875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="1">
        <location>
            <begin position="38"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="1">
        <location>
            <begin position="102"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="18494" checksum="4E2C5C0F82E63190" modified="2018-01-31" version="1">MNIISGFPDGTFKPDQGLTRAQYAALLAKAFELAPRRDATNFKDVAADFWAKVAIEKANRGGFLAGYPDITFRPNQNLTRAQAVVSLVNGLQLGGGNPNSLSVYSDRALIPSFATAQVATATERKMVVNYPARDRFSPARDITRGEISALIYQTLVATNRTQPINSPYIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4U6</accession>
    <name>A0A2G4F4U6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56517">
        <property type="protein sequence ID" value="PHX56517"/>
        <property type="gene ID" value="CP500_005025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="134"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="225" mass="25387" checksum="9142C77A7959C2BD" modified="2018-01-31" version="1">MTVRNEAPQILYLQQSQIPAAAKLMAETFLPDPVSCYLMPNERHRVKILEKAWSEMINHDIHLGNVYASHHSNSNASASIGSSQLLGIASWLPPNAKSPSLLQSLPLIFEIFLQSGFRSTSRILNTLTKTEAYRLRDCPTPHWYLDGLAVSPTTQGKGIGSMLLQPVLQQADHQGEICYLYTSTPRAVKFYQRHGFVVRDELRILNDAPPLWMMMRSPKNQDSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4V9</accession>
    <name>A0A2G4F4V9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56824">
        <property type="protein sequence ID" value="PHX56824"/>
        <property type="gene ID" value="CP500_003235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="99" mass="10860" checksum="8B72AB460347BA47" modified="2018-01-31" version="1">MPTLTDIGTLIIRDPHLRGGIPIIAGTATSVQRIVVLYKQGNSAEEIAADLDHLTLAQVYAALTYYHANRAEIEADLVAEQAEYERLAALNKLKMQEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4X4</accession>
    <name>A0A2G4F4X4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_003455</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56796">
        <property type="protein sequence ID" value="PHX56796"/>
        <property type="gene ID" value="CP500_003455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="14"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="342"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="356"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="436"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="598" mass="65309" checksum="BA9A3A3CF1E1D3D4" modified="2018-01-31" version="1">MDALIGKTLQGGKYTLEQELGRGGFGITFRATHRYLGQFVVIKTLNESLRRQPNFAEFDRKFQDEARRLASCVHPNIVRVSDFFVEDGQPYMVMDYIPGQNLGDVVQPNRPLPEAVAIIYITQIGAALKAVHQKGLLHRDIKPQNIILRQNTQEVVLIDFGIAREFTPGVTQNHTNMVSDGYAPPEQYFAQGKYTPATDVYALAATLYTLLTAQVPMPAVFRPSQPMATPRDLQPQLSAAISQAVMRGMTLDAENRPGTVDEWLSLLPNSQSPSTGPTLAVMPGHGPMMPAGARTAPAVVPSGAGESKIWLILGLVAIALIFAGFVGIARILLDRQSDRPAPIAQENRTSPPAETSTPDRPSPIPTPEATPKPRRKTPTPAAIPTPKETPAPAVETPPPAIETPTPAIETPAPKPSPVAESPKPSPVAESPKPTEKPVENQATDRSTPTPSPREEQPATSNQKIPRVPGFAVGTPESQILEQLGKPTDTQRKGYWPNTRTALYDLVPNRITLGYIYDRDSGQLVQTEGSFAQSVDDLVVRTALNGMLGGADEKVMEGFRDVHQRRKSRFTFRKGALKGAIERNERDRIYIGVWDDNLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F508</accession>
    <name>A0A2G4F508_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tfp pilus assembly protein PilF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_004850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56577">
        <property type="protein sequence ID" value="PHX56577"/>
        <property type="gene ID" value="CP500_004850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="196"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="261"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="309" mass="32635" checksum="E2101FC15DEAA93D" modified="2018-01-31" version="1">MEKANKGRGLITVVVVLSLIAFLGFSLVPILDSILKASQTTTRSTPTPTQTAAAGEKPELLQAQARGYELVLQREADNVTALRGLLQVRLELIGQGVGDIKDVVSPLEKLAKLNPETTEYGILLAQAKERTGDREGSAQAYRSILASKPGEIKALQGLVNLLLVQQRPEAAIGLLQDTLKAAPAANLAKPGSVDVISVQLILGQVYAVQKRFEEAIAIYDESAKANPKDFRPTLGKAIVFKEQGKTDEAKTLFAKATELAPPNYKDQINQLASDTPKPSPAAAASPKPGASPSPKPGASPSPEGALPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F574</accession>
    <name>A0A2G4F574_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">HlyC/CorC family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_004300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56637">
        <property type="protein sequence ID" value="PHX56637"/>
        <property type="gene ID" value="CP500_004300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="8"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="298"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX56637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="487" mass="53439" checksum="557C40DC621CFAE7" modified="2018-01-31" version="1">MAELPAMTWTEVLSRLLSVLLLIAINAFFVAAEFSMVTVRRSRIHQLVEAGDAPAITVQSLLQSIDRLLSTMQLGITLSSLALGWIGEDTIAVLIRVSIGFLPLPTYIQESIAHSFSISIVTFFLLAYLQIVLGELLPKSVALLYSEKLARGLGTPSLLIARLFNPFVSFLNQSTRSLLWLVGIEYDVTHRPVTPEELQLIIATSSESSGLQADERELLNNVFEFGEVLVEEVMVPRPSIVVLPKTATFQCLLSEIAISNHSRYPMTGDSFDDIIGIIDFKRLAKPLAEGLLSPDTPIVNWICPVRFVPEMMLLGELLPLMQRSSEEIAIVVDEFGGISGLVTLRDLIAEIIGRSYESPDSKEIALQVLDDRTFLVQAQLNLDDVNQILNLDLPVTDEYQTIGGFLSYQLQRMPAVGEVWRSENVELAVVSVCGPRLDQIQVQLLEGVAGDRNLGEVAAADGEIVGKGRSNSGLRGVAKFPSSEYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F585</accession>
    <name>A0A2G4F585_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56899">
        <property type="protein sequence ID" value="PHX56899"/>
        <property type="gene ID" value="CP500_002665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="200" mass="22310" checksum="9B95107F943DAEBB" modified="2018-01-31" version="1">MPYSSFTTIGKVKEAFNLTTVESVRFLPNIDPISPSQTLTAFLEESLPLASSASEKARSEGIIYPVLLEARRILQRRVSLFSGEDFTVDESMGLNGMCDFLFSRSEEILEIEAPAVIIVEAKKSDLRTGFGQCIAEMVAAQKFNEAKKKPIPIIYGSVTNGTQWRFLKLEGQIVTIDLIDYPLPPVDQILGFLVWMAREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5G0</accession>
    <name>A0A2G4F5G0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit c</fullName>
            <shortName evidence="13">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">atpE</name>
        <name evidence="13" type="synonym">atpH</name>
        <name evidence="15" type="ORF">CP500_002515</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cellular thylakoid membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_017712264.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56979">
        <property type="protein sequence ID" value="PHX56979"/>
        <property type="gene ID" value="CP500_002515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031">
        <property type="entry name" value="PTHR10031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="14">
        <location>
            <begin position="11"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="13">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX56979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="7986" checksum="9D027F0F868C06EC" modified="2018-01-31" version="1">MDPIVAAASVIAAALAVGLAAIGPGIGQGNAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALVLLFANPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5H9</accession>
    <name>A0A2G4F5H9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56961">
        <property type="protein sequence ID" value="PHX56961"/>
        <property type="gene ID" value="CP500_002425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="190" mass="21449" checksum="67AB560D896E47C4" modified="2018-01-31" version="1">MTQSPTIISVDRILEQDAESILIWIKNIFSAQTAQPQDFNWLLLADVASTKARKGQNGSGFCDRTWAQVATTIYDRLSEAAEQQKPGSGESFTISSMMLRAGAIAKLGVISDDPVLDVNLILQWFWDNIKESREDVNKKAANWKTLPIAEIRELRQLKNRLKVIAALADTDKYVLDEELSTWLDLREKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5V9</accession>
    <name>A0A2G4F5V9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplX</name>
        <name evidence="3" type="synonym">rpl24</name>
        <name evidence="6" type="ORF">CP500_001760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="3">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57146">
        <property type="protein sequence ID" value="PHX57146"/>
        <property type="gene ID" value="CP500_001760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="120" mass="13547" checksum="43DFE94310000F60" modified="2018-01-31" version="1">MYGKKGKPTSEPQRHRMHVKAGDTVQIITGKEKGKVGEILRTYPKLSKVIVKGVNVRTKHVKPQQEGESGKIVTFEAPIHSSNVMHYSEKEKVASRVCYTFSEDGRKLRQLKKTGEILDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Z7</accession>
    <name>A0A2G4F5Z7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57192">
        <property type="protein sequence ID" value="PHX57192"/>
        <property type="gene ID" value="CP500_001325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="120" mass="13466" checksum="5AEFCF4FC150260F" modified="2018-01-31" version="1">MDNGKDLESGKLQSQLQSLTEAIRTLAESCQGDSVLLLALLRALESSHREIRDGLFQASFPDNRQALYKLLRSIEANGGWPYIHRMKLREILGYTEKLSILEDSPAKSDCDSADNRQDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F628</accession>
    <name>A0A2G4F628_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="8" type="synonym">rps3</name>
        <name evidence="13" type="ORF">CP500_001785</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57151">
        <property type="protein sequence ID" value="PHX57151"/>
        <property type="gene ID" value="CP500_001785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="12">
        <location>
            <begin position="39"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX57151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="242" mass="27496" checksum="45990F6176FF8B79" modified="2018-01-31" version="1">MGQKIHPIGFRLGITQEHRSRWFADARNYPELLQEDFKIRKYVRKNLSNAGISSVRIERKADQIDLEVFTARPGVVVGRGGAGIETLRVGLQQLLGSNRQIRINVVEVQRVDADATLIAEYIAQQLERRVSFRRVVRQAITRAQKVGIEGIKIQVSGRLNGAEIARTEWTREGRVPLHTLRADIDYSYCTAQTIYGILGIKVWVFKGEIIPGQEQIAAPNAALPRNKNKRRRQDFEDRSNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F639</accession>
    <name>A0A2G4F639_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="6 8">5.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">glmM</name>
        <name evidence="13" type="ORF">CP500_001025</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23424"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="5.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Activated by phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="6 8"/>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57254">
        <property type="protein sequence ID" value="PHX57254"/>
        <property type="gene ID" value="CP500_001025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05802">
        <property type="entry name" value="GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01554_B">
        <property type="entry name" value="GlmM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006352">
        <property type="entry name" value="GlmM_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01455">
        <property type="entry name" value="glmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="39"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="192"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="292"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="411"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="6">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="6">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX57254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="486" mass="52547" checksum="B5F748BFB2078A87" modified="2018-01-31" version="1">MVQTPSRHRGSEFQAANSVQPAKRDSILVGNNLSLPNTKLFGTDGIRGKVGELLNAPLATQIGFWAGQVLRQNCPNQGPVILGQDSRNSSDMLAMALSAGLTAAGLEVWNLGLCPTPCVAYLASVSESVGGVMISASHNPPEDNGIKFFGSNGSKLSQQLQEQIEAGIRGTKVPISSTICGHHYHRPELVKDYAASLEGSLQGVNLRGMRIVLDLAWGAAARLGPAVFEQMGANVICLHNSPDGDRINVNCGSTHLNSLQAALLEHNADLGFAFDGDADRVLGVDNKGRSIDGDYILYLWGRHLRHREKLPDNLIISTVMANLGFERAWEELGGKLIRTSVGDQHVHAEMERTGSMLGGEQSGHILCPHYGISGDGLLTALHMASLVRESGESLAQLVDSSFETYPQLLRNVRVDDREKRLKWHDCETLQGAIGRAKTAMGEEGRVLVRASGTEPLIRVMVEASSHELANFWTENLVLAVQKYQTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F656</accession>
    <name>A0A2G4F656_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57205">
        <property type="protein sequence ID" value="PHX57205"/>
        <property type="gene ID" value="CP500_001415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="157" mass="18010" checksum="EBCF1812B41BFAF1" modified="2018-01-31" version="1">MVGNNAWTQNIKEWIEQNHPNLVITGYKITSPDTTDYNCIAWAAGSTEEWWWPDAKGQDYWPPNILREESLTAFIMAYQTLGYEVGDNASLEAGFEKIAIYVLDEKPQHSARQLPNGMWTSKLGQYEDIEHNTLEGLEGSIYGYVACVMKRRLTDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6A7</accession>
    <name>A0A2G4F6A7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57279">
        <property type="protein sequence ID" value="PHX57279"/>
        <property type="gene ID" value="CP500_001170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="80" mass="9261" checksum="A88137F37CD09D6C" modified="2018-01-31" version="1">MFTYSNVLNQVKSLTIADQLRLLEDLKKMIQLREEVAEDDEVISAEEIAESEAAWQDYQAKRDRGISSQELKLKLFGEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6C7</accession>
    <name>A0A2G4F6C7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA interferase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Toxic component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PemK/MazF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57275">
        <property type="protein sequence ID" value="PHX57275"/>
        <property type="gene ID" value="CP500_001145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR033490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="12538" checksum="DAF75416ABA3C7FD" modified="2018-01-31" version="1">MNRGEVYDARLEPVEGSEQGGTRPVIIVSRATINTYSPVVLAIPCTTYQTGKRVYPTQVLIKTPDGGLTNDSIAMADQVRVLSKSRLLSLRGMLSDEAILLLNQALLIALDLPGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6D3</accession>
    <name>A0A2G4F6D3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57316">
        <property type="protein sequence ID" value="PHX57316"/>
        <property type="gene ID" value="CP500_000605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039060">
        <property type="entry name" value="Antitox_HigA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40455">
        <property type="entry name" value="PTHR40455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="123" mass="14175" checksum="E3CC749DE54C1574" modified="2018-01-31" version="1">MYSLQPIRSQEDYKASLKEIERLFEAPQGTPEFDRLEILVTLVEAYENKHEPIVMPDPIEAILYYLESRGLTQQHLESVIGSHDRAIEILNRKAPLTLEIIRQLNQKLGISAQVLIQPYALAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6L1</accession>
    <name>A0A2G4F6L1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57331">
        <property type="protein sequence ID" value="PHX57331"/>
        <property type="gene ID" value="CP500_000695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="7495" checksum="B2EA226A75068F82" modified="2018-01-31" version="1">MNKQPRIPDPETSKRLLANLRRTRLEVQEVNLELGEINAMLAEQLRQQRLNRVRRALDSSTVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6M2</accession>
    <name>A0A2G4F6M2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsM</name>
        <name evidence="5" type="synonym">rps13</name>
        <name evidence="8" type="ORF">CP500_001705</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57137">
        <property type="protein sequence ID" value="PHX57137"/>
        <property type="gene ID" value="CP500_001705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="97"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="127" mass="14388" checksum="EE7F1F9CEC1E19E2" modified="2018-01-31" version="1">MARIAGVDLPRDKRVEIGLTYIYGIGLSRAQKIIAATGVNPDTRVKDLTEADVTALRLHVEANYQIEGDLRRWESMNIKRLVDIGTYRGRRHRLGLPVRGQRTRTNARTRRGVRRTVAGKKKAPSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6R7</accession>
    <name>A0A2G4F6R7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57187">
        <property type="protein sequence ID" value="PHX57187"/>
        <property type="gene ID" value="CP500_001280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013639787" evidence="1">
        <location>
            <begin position="26"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="17089" checksum="72B3502964793DAF" modified="2018-01-31" version="1">MKILHFILTLSILLTSLISAKSLLANTANPLAQNSEIDEPFCYMRTTDGKTVDLGKLCENKTPSRTSQSCIAGSNIAAKVSINNVNYDGKFLSGQIINQGCKLVKNIKVNYEVLDELGNSIDNGFIATQPVTVEPGKSATFRGEVVAGAKVLATHADGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6W7</accession>
    <name>A0A2G4F6W7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57317">
        <property type="protein sequence ID" value="PHX57317"/>
        <property type="gene ID" value="CP500_000610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="14449" checksum="43C4E961DF4206C1" modified="2018-01-31" version="1">MSNQQDIIAELVNSLREKSSANEEEKSYGEEHLAQLRDACENFLKKESFEVGQIVKWKKNLNNRKLPHQNQPAIVVRLLEEPIVSSDDESGSPYFLEKLDIVLGVMSDRGTFLVFYYDSSRFESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUI9</accession>
    <name>A0A2G4EUI9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AbrB family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000246">
        <property type="protein sequence ID" value="PHX53194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53194">
        <property type="protein sequence ID" value="PHX53194"/>
        <property type="gene ID" value="CP500_022785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="3"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="73" mass="7910" checksum="9E3E0CDAF0794152" modified="2018-01-31" version="1">MLAKLTSENQLTLPKSITQAIGAAEYFEVKIEGGQIILTPVKNQGADSVRAKLGALNVNEQDITDAVEWARQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUJ9</accession>
    <name>A0A2G4EUJ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000244">
        <property type="protein sequence ID" value="PHX53204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53204">
        <property type="protein sequence ID" value="PHX53204"/>
        <property type="gene ID" value="CP500_022755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="87" mass="9921" checksum="3D929AAF78D49BAA" modified="2018-01-31" version="1">MFLIAENLTASNFHCIILKSSRPLWIGGTFNLYGFGQFLELIHKFGYKNTTLESRFLASVDLRTGKKQKQKEQNVICQLLKGDILPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUN6</accession>
    <name>A0A2G4EUN6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000229">
        <property type="protein sequence ID" value="PHX53253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53253">
        <property type="protein sequence ID" value="PHX53253"/>
        <property type="gene ID" value="CP500_022490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="13895" checksum="5FCD5C551B4D48C9" modified="2018-01-31" version="1">MITVTQAEIEQYRSQLQAYPDALKGLDVLAECEGDLEYAAETIAIESGELQDNLGEEDPNEPSQLEKLAEQLRPHICTQAFKETFNDGFAAAIGLLTPLVGFPILLIFVLIYISRRGLDKFCKDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUS8</accession>
    <name>A0A2G4EUS8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Photosystem I reaction center subunit PsaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Photosystem I subunit X</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">psaK</name>
        <name evidence="10" type="ORF">CP500_022285</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the PsaG/PsaK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000222">
        <property type="protein sequence ID" value="PHX53284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53284">
        <property type="protein sequence ID" value="PHX53284"/>
        <property type="gene ID" value="CP500_022285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.860.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00474">
        <property type="entry name" value="PSI_PsaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035982">
        <property type="entry name" value="PSI_centre_PsaK_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000549">
        <property type="entry name" value="PSI_PsaG/PsaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017492">
        <property type="entry name" value="PSI_PsaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037101">
        <property type="entry name" value="PSI_PsaK_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01241">
        <property type="entry name" value="PSI_PSAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81563">
        <property type="entry name" value="SSF81563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03049">
        <property type="entry name" value="PS_I_psaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01026">
        <property type="entry name" value="PHOTOSYSTEM_I_PSAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="94" mass="9757" checksum="B830C9E8E48EC43C" modified="2018-01-31" version="1">MIYSSLLLVVQSTIPTTPEWSPMVGLTMILCNLLAIAIGYYGISKENRGKGPALPLVMPGMFKGFGIPELLATTSLGHLLGAGVILGLGNSGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUY3</accession>
    <name>A0A2G4EUY3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pstS</name>
        <name evidence="7" type="ORF">CP500_021930</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PstS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53349">
        <property type="protein sequence ID" value="PHX53349"/>
        <property type="gene ID" value="CP500_021930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013660032" description="Phosphate-binding protein" evidence="5">
        <location>
            <begin position="31"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="6">
        <location>
            <begin position="64"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="396" mass="41093" checksum="47374A5C476B70B6" modified="2018-01-31" version="1">MLSRLNLINSNRLTTAISAMAIALSLAACGGGSTTTSSPSPGDTAASPGATPGASPVAATGTATPSKLALASDVAITAAGASFPAPLYQRWFQDFNKINPKVQINYQSTGSGAGVEQFTKGTVDFGASDTAMKDDEIAKVPADKGVILLPMTAGSIVIGYNLADVPELKLPRDVYTEIFAGKITKWNDPKIAAANPGAKLPDQAITIVHRSDGSGTTAVFTKHLSAISPDWKSAVGDGKTVQWPVGVGAKGNEGVTAQVLQTVGSLGYVEYGYAKNNNLKFASLQNKAGTFVVPSDESASAALATVPLPENLRVFIEDPEGAQSYPIVTYTWMLLPKTVADANKAKAIEAMVEYGLNEGQKVSSELGYVPLPQSVKEKVALAADGISPDYKIEVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV16</accession>
    <name>A0A2G4EV16_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="9">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argS</name>
        <name evidence="13" type="ORF">CP500_021805</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000206">
        <property type="protein sequence ID" value="PHX53375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53375">
        <property type="protein sequence ID" value="PHX53375"/>
        <property type="gene ID" value="CP500_021805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="12">
        <location>
            <begin position="6"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="468"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX53375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="585" mass="65040" checksum="C315B34A60331416" modified="2018-01-31" version="1">MFSTTSKLKARFDKAFTAAFGESASGIDPMLTAASNPNFGDFQCNAAMSLGKKLKKSPRAIAQTIIENLDIADICETPEIAGPGFINLKLKPAYLEAEVRAIAIDPRLGISQIEAPQRIAIDFSSPNIAKEMHVGHLRSTIIGDAIARILEFLGHDVIRINHIGDWGTQFGMLIAYLREVHPEALTTANALDLGDLVAFYRQAKQRFDADETFKETARQEVVKLQAGAEDTRRAWKLLCDQSRREFQVIYNLLDIKLTERGESFYNPLLPAVVEDLTNLGLLVESDGAKCVFVDGFTNKEGEPLPLIVQKTDGGYNYATTDLAAIRYRIEEDGAKRIIYVTDSGQANHFAQVFAVARKANWIPEDVEIVHVPFGLVCGEDGKRLKTRSGDAVRLQDLLDEAIVRTRADLETRLVAEERQETEEFITNVSEVVGLSAVKYADLSQNRASNYVFSYDKMLALQGNTAPYMLYAYVRVQGIRRKGGIDFDNLDAGAKVILQSDAELVLAKHLLQLNEVLGSVDGDLLPNRICQYLFELSQKFNQFFEQCPVLKAEEPLRSSRLILCDLTARTLKLGLGLLGIQVLERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV31</accession>
    <name>A0A2G4EV31_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Long-chain fatty acid--CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_022320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000222">
        <property type="protein sequence ID" value="PHX53290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53290">
        <property type="protein sequence ID" value="PHX53290"/>
        <property type="gene ID" value="CP500_022320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="23"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="56"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX53290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="261" mass="29050" checksum="D065D9CECB00E29B" modified="2018-01-31" version="1" fragment="single">PPNPPLLRGGENPKSQDLESGEIQFENVWFAYKEDEYVLQNLNFTIKSGEKVALVGPTGAGKSSIIRLLCRLYEPTKGRILINHVDIRDLPQAELRRHIGVIIQDGFLFAGDVKSNISLGENYSIEEIQAAAEKTNVAKLIEELPQGYDTQLRQRGTNLSGGQKQLLAFARAAIRNPSILVLDEATASLDVGTEALIQEALERLMVERTAIIIAHRLSTIRNVDRILVLKRGQLIESGSHDELLQQEGLYASLYKLQMLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV79</accession>
    <name>A0A2G4EV79_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000204">
        <property type="protein sequence ID" value="PHX53388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53388">
        <property type="protein sequence ID" value="PHX53388"/>
        <property type="gene ID" value="CP500_021755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7268" checksum="2976FF2F1FC728F3" modified="2018-01-31" version="1">MVRAVGRKKEEGRGKREGATIAMVSEIKNVLNVGRGCGALVIYNCMSFWRSLGVRVGPGFQGILQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVA3</accession>
    <name>A0A2G4EVA3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Membrane protein insertase YidC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_021380</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000194">
        <property type="protein sequence ID" value="PHX53461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53461">
        <property type="protein sequence ID" value="PHX53461"/>
        <property type="gene ID" value="CP500_021380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="382" mass="42072" checksum="179FE7E01CDFB5E8" modified="2018-01-31" version="1">MDFGISFLSSNLMLPILDFFYGIVPSYGLAIVALTLVIRFALYPLNAGSLRNMRRMKVAQPLMKERVDQIQKLYKDNPTKQQEEMSQVYKEFGNPLAGCFPLVIQMPVLFALFATLRGSPFSDINYTVNVQVLPKEQIEVVQPQAFATPPQNIYVTGTFHAPIIGVIPGGDKLAVGDKTKIEFQTPEGKPLSAVATENKSETDFVPRWTITKGEELAKIDEQGNIVAIAPGEVTVQGTIPGLATNKGFLFIEALGRVGAIDPDGTIHWDILVMILGFGISLYINQTLSGQAQGPNDNPQQATVNKLTPVIFSGMFLFFPLPAGVLMYMLIANIFQTVQSFILSREPLPENLQKIVDEAEAKTKKEQGLDAIPFEPKRPKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVB9</accession>
    <name>A0A2G4EVB9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">B12-binding domain-containing radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000205">
        <property type="protein sequence ID" value="PHX53380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53380">
        <property type="protein sequence ID" value="PHX53380"/>
        <property type="gene ID" value="CP500_021775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025274">
        <property type="entry name" value="DUF4070"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034530">
        <property type="entry name" value="HpnP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13282">
        <property type="entry name" value="DUF4070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00303">
        <property type="entry name" value="hopanoid_C2-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="164"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="528" mass="60269" checksum="628ABCFFE73A5A17" modified="2018-01-31" version="1">MNVLLVYPQFPKSFWSFEKTLALLNRSAMLPPLGLVTVAAILPQDWQFKLVDRNVRQVTEAEWAWTDLVILSAMIVQKEDLLFQIQEAKRRNKQVAVGGPYPTALPDEAKTAGADYLILDEGEITLPLFVEAIGNGVTSGIFRAGGERPDVTGTPIPRFDLLEFEAYAEMSVQFSRGCPFQCEFCDIIVLYGRKPRTKNPDQIIAELDRLYELGWRRSIFMVDDNFIGNKRNVKLFLKELLPWMVEHQYPFSFATEASVDLANDQELMDAMVACNFGSVFLGIETPDEESLALTQKYQNTRSSLSEAVERITRTGIRVMAGFIIGFDGEKTGAGARIVQFVEQTSIPTALFSMLQALPDTALWHRLAKEGRLRKESANINQTTLMNFVPTRPLEEIAHEYIEAFWELYEPKRFLDRTYRHYRLLGEATYPKKGKNSSKKVNWVTIRALLTICWRQGALRSTRWQFWSHLLSMAYHNPGGVSSYLSVCAQIEHFFEYRQIVRDEIEAQVAEFLATDVEPIKSVENMALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVC6</accession>
    <name>A0A2G4EVC6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CP500_021765</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000204">
        <property type="protein sequence ID" value="PHX53390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53390">
        <property type="protein sequence ID" value="PHX53390"/>
        <property type="gene ID" value="CP500_021765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="16">
        <location>
            <begin position="373"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="455"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="582"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="15">
        <location>
            <begin position="656"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="732"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX53390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="969" mass="108086" checksum="3DBC4C1918CED873" modified="2018-01-31" version="1">MQIKYLTNPILKMSGKVPIGIILVVPFALQTFAAVGLTGWLSLRNGRIAVNDVATQLRAEVTSRIQQHIHSYIETPHQVNQLNVDAIRLGILNVQDSASLRRYFSKQIQTFNKISYIQFGSEQKDFTGVERLDDGKLQVLKSDQSTGYSFQTYAVSELGEPTELLQITPNYDPRIRPWYTAPVLANKPAWTKIYTYFDSPKLAITAAAPVYGDRGELIGVVGCDLLLSQINQFLDSLTIGKSGQTFIVERSGQLVANSTPEPPFILSKGVAKRIMATDSKNALIRSTARYLTKRFGDLSKIDGTYQLDFAIDGERQFLQVTPLSDGRGLNWLIVVAVPEADFMEKINSNTRYTVLLCLGALVVATLLGYLTSRWIVAPIQRLSKAAEGLSRGEWDSTAVDTHLMASVEREDELGILARSFNQMAGQLEESFTTLEDRVESAIADKTQLINSLKKSQQKLALHLHQTPLGAIEWNLNFEVEDWNLSAERIFGYDRLEAVGKHGVDLIVPESAKEYVRQLFITLLTNQGGISSINENVRKDGKIILCQWYNTTLINTEGCIIGVASLVQDVTEFQTTLAQLRASEERFRQLAENIHEVFWIREPHHSQIVYVSPACEKIWHRSSQILCSKPESFWEAIHMDDRDRVKAAFEKQVRGDYDEEYRVVRSPTGATPTEGSVCWVRDRAFPVRNETGEIYRIVGIAEDITQRKLAEEFQKVAQTAQAANQAKSAFLANMSHELRTPLNAIIGYSDLLKEDAEDLGCENFIPDLHKIQTAGKHLLSLISDILDISKIEAGRMELYLETFNPANLIDDVVLTVESLVEKNSNQFEVDCASDLGVMYADVTKTRQILLNLLSNAAKFTKGGIITISVERVTNKTSKIPKPEYSSDSIIFRVADTGIGIPPEQLQHLFQAFMQGDASTTRQYGGTGLGLTISRHFCLMMGGDLQVESELGCGSVFTVRLPAHVELLVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVF3</accession>
    <name>A0A2G4EVF3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000196">
        <property type="protein sequence ID" value="PHX53446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53446">
        <property type="protein sequence ID" value="PHX53446"/>
        <property type="gene ID" value="CP500_021430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH crp-type" evidence="2">
        <location>
            <begin position="128"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="217" mass="24500" checksum="3B142D3986A024AE" modified="2018-01-31" version="1">MPLTSKALLAESQQNTGVNRNLHFYAKGETIPLMSQGLWQVCQGLVQLSTLYPSGEEGLLGWAGPSMCFGLWLTSLQTYRATATSDVYLIWYSMVEIEASPQLAQDLLPQMGRRLRQMEAILAIAGQRRVEDRLYQLLLLLKQEFGQPVLEGTRLNIRLTHQDIANAICTTRVTVTRMLGKLQQQDLISRDKDRHLILKKDAFASVSDLFGYKPQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVG7</accession>
    <name>A0A2G4EVG7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Metal-dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000182">
        <property type="protein sequence ID" value="PHX53531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53531">
        <property type="protein sequence ID" value="PHX53531"/>
        <property type="gene ID" value="CP500_020980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="326" mass="36636" checksum="3A6B91E37CA545C8" modified="2018-01-31" version="1">MFNATAILIDAFVQELQAGYRRTYGKYKPDYPEIIAWAGTMALENIANCDALYHNVEHTMLVALVGQEILRGKHIREGGVLPEDWLHYLISLLCHDIGYVKGVCRQDQEAVGRYATGIDGHMVSVPIGATSASLTPYHVDRGKLVIDERFGGHTLIDAEQIKRNIELTRFPVPASETHQDRNNYSGLARAADLIGQLSDPNYLRKISALFYEFEEVGTNKILGYKSPGDLRQNYAKFYWNGVFPYIPAALNYLDLTQGGKQIVANLYANVFQVEHAEPLAFTKVNSQDLPEFNSNSNFNREKDAEILQLATSGEKKKFSEFPNLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVH5</accession>
    <name>A0A2G4EVH5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Shikimate kinase</fullName>
            <shortName evidence="10">SK</shortName>
            <ecNumber evidence="3 10">2.7.1.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">aroK</name>
        <name evidence="11" type="ORF">CP500_021330</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="3 10"/>
    <dbReference type="EMBL" id="NXIB02000193">
        <property type="protein sequence ID" value="PHX53466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53466">
        <property type="protein sequence ID" value="PHX53466"/>
        <property type="gene ID" value="CP500_021330"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX53466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="20536" checksum="06E5D6DA1FA48681" modified="2018-01-31" version="1">MDLLRGANLYLVGMMGVGKTTVGRILAKELKYHFFDTDLVIAQVANQSIADIFATQGEEEFRELETKVLGQLCAYTNLVVATGGGTILRLTNWSYLHHGIVVWLDVPVDQLCDRLRDDITRPLLREGDLKSKLETLWKERERFYTQADVRVCANVSDSPEVVAARAIEEIQKAIKAKIGNDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVN2</accession>
    <name>A0A2G4EVN2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsG</name>
        <name evidence="6" type="synonym">rps7</name>
        <name evidence="10" type="ORF">CP500_021080</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000184">
        <property type="protein sequence ID" value="PHX53526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53526">
        <property type="protein sequence ID" value="PHX53526"/>
        <property type="gene ID" value="CP500_021080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="9">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="17716" checksum="214161206B81D1A5" modified="2018-01-31" version="1">MSRRTVIQKRPVPPDPTYNSRLVSMMVRRIMQHGKKSVASSIVYDALKTIQERTGAEPLDLFEKAVKNATPLVEVKARRVGGATYQVPMEVRQDRGTTLALRWLIRFARARTGRSMAAKLANELMDAANETGSAIRKREETHRMAEANKAFAHYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVT0</accession>
    <name>A0A2G4EVT0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Competence protein ComFB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000177">
        <property type="protein sequence ID" value="PHX53560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53560">
        <property type="protein sequence ID" value="PHX53560"/>
        <property type="gene ID" value="CP500_020820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019657">
        <property type="entry name" value="ComFB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10719">
        <property type="entry name" value="ComFB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="179" mass="19656" checksum="DB236685FD977C24" modified="2018-01-31" version="1">MSIEKIVEQALQDGYLTPSMEAEVGRICNTASELSIEEYMALDRLMGALLTGEVVVLPRKQFINVMEELVLSDVIARVAEIEGTSDQSLDVGDIAAYALNRLPPLYATTEEGAHFQRARAKDQLYDLISKEVQAAIDRNLDRPEPVHPTALGKPSSGSEVLSNLSNWLQANAANFEQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVV8</accession>
    <name>A0A2G4EVV8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADPH-dependent 7-cyano-7-deazaguanine reductase</fullName>
            <ecNumber evidence="1">1.7.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">7-cyano-7-carbaguanine reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NADPH-dependent nitrile oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">PreQ(0) reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">queF</name>
        <name evidence="2" type="ORF">CP500_020230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-aminomethyl-7-carbaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH</text>
            <dbReference type="Rhea" id="RHEA:13409"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="EC" id="1.7.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.13" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000164">
        <property type="protein sequence ID" value="PHX53675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53675">
        <property type="protein sequence ID" value="PHX53675"/>
        <property type="gene ID" value="CP500_020230"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046857">
        <property type="term" value="F:oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033739">
        <property type="term" value="F:preQ1 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00818">
        <property type="entry name" value="QueF_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029500">
        <property type="entry name" value="QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016856">
        <property type="entry name" value="QueF_type1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14489">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027377">
        <property type="entry name" value="Nitrile_oxidored_QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03139">
        <property type="entry name" value="QueF-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="60"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="79"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimide intermediate" evidence="1">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="14036" checksum="C75B56BC4D2DF5CA" modified="2018-01-31" version="1">MKYGEREILDGELITFPNPRIGRRYFVNITLPEFTCKCPFSGYPDFAAIHITYVPDERVVELKALKLYINSYRDRYISHEESINQILDDFVAACSPLEATIKGDFLPRGNVHTVIEVRHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW06</accession>
    <name>A0A2G4EW06_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53715">
        <property type="protein sequence ID" value="PHX53715"/>
        <property type="gene ID" value="CP500_019965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037359">
        <property type="entry name" value="NST/OST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10605">
        <property type="entry name" value="PTHR10605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransfer_1" evidence="2">
        <location>
            <begin position="7"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="254" mass="29791" checksum="325D94B1E9978366" modified="2018-01-31" version="1">MNPIPKPPDFIIIGAQKGGTTSLYAYLTQHPQIAHATQKEVHYFDLNFDKGADWYYSQFPQPENGPYKITGEASPYYIFHPHVPGRMHDLCPEVKIIVLLRNPVDRAISHYYHYIRIEYESLSLEEAIASEPKRLKGEIEKLLANPNYYSYEHQHHTYLKRGIYADQLPLWMQLFPKEQILIIKSEDLYTNPSETVNTVLDFLDLPPQQLETYGKHNSNEYPPISEAVYEQLRAYFRSHNQRLAELCDRDFGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW72</accession>
    <name>A0A2G4EW72_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000161">
        <property type="protein sequence ID" value="PHX53706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53706">
        <property type="protein sequence ID" value="PHX53706"/>
        <property type="gene ID" value="CP500_020105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="17131" checksum="ECDDC95007CBB035" modified="2018-01-31" version="1">METTNLIALSVIIVTVLGIGVGTMTWAYFGKGSVSVLFKEPILSLPEFPATDAGKKASVYFQQGIQAYQSGNYRQAKDKFTSAIQLVSTLAEAYHNRGLVFANLRSDDDAVVNLISASELYQQQDNGVAIDMIKKNLEALKQRKLEREKLKNQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW80</accession>
    <name>A0A2G4EW80_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Copper chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000160">
        <property type="protein sequence ID" value="PHX53716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53716">
        <property type="protein sequence ID" value="PHX53716"/>
        <property type="gene ID" value="CP500_019970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="6688" checksum="9936E7B43BB5941E" modified="2018-01-31" version="1">MPILFNVPSIVCSGCGDTIVKAIKTVESDASVNVDVAAKTVTVEAKASEESIKQAIVASGHTIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWD2</accession>
    <name>A0A2G4EWD2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53750">
        <property type="protein sequence ID" value="PHX53750"/>
        <property type="gene ID" value="CP500_019750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="92" mass="10812" checksum="44BE33BD7250DE6F" modified="2018-01-31" version="1">MEAFAPNPPEWTATAVHAYEFCCPRCGASCTEAHEVWINRRSPVYTEFNRRKWQEFYRCQCGGIWWAWSSDRPPSELVRSDEITNESSDNDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWE6</accession>
    <name>A0A2G4EWE6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000148">
        <property type="protein sequence ID" value="PHX53853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53853">
        <property type="protein sequence ID" value="PHX53853"/>
        <property type="gene ID" value="CP500_019230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7250" checksum="5BC8A49D381E2604" modified="2018-01-31" version="1">MLVILMENQMLAPQCVCQGCLLADRTGQPRWSGGELRCGHPVSKPTENLPDRYECQMGFTIANIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWG8</accession>
    <name>A0A2G4EWG8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-binding oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000144">
        <property type="protein sequence ID" value="PHX53885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53885">
        <property type="protein sequence ID" value="PHX53885"/>
        <property type="gene ID" value="CP500_019075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="43"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="444" mass="47770" checksum="7F27FCD048AF5A8C" modified="2018-01-31" version="1">MKSVYRVNLAHIKELESIVDAAGVSCWQDTEAFWQQRLETAVFPSTQIDSIVYPNTQAELAAVIAWAGQNGYAVLPCGSGTKLDWGGLVKLDSPNVRLMAVSTSRLNRLVEHAVGDLTVTAEAGMRFADLQQVLATAGQFLPIDPAYPQHATLGGMIATADTGSLRHRYRGVRDLLLGMTFVRSDGKIATAGGRVVKNVAGYDLMKLFTGAYGTLGVISQVTFRVYPLPESSGSLVLTGETNALIQATQILLSSALTPTAVDLLSPDLVTKLGLGKTTGLIVRFQSIAESVKQQSARLLEVGEKLGLQANICREKDENQLWQTLPETIWNSPQNSTIICKIGIKPSESVKLIDQFPIQDAVIHAGSGLGILRFDETATAEVIGKIRRGCEAKGGFLTVLVAPAALKQELDVWGYTGSAIDVMRGIKQQFDSENVLSPNRFLSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWJ2</accession>
    <name>A0A2G4EWJ2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-splicing ligase RtcB</fullName>
            <ecNumber evidence="4">6.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rtcB</name>
        <name evidence="5" type="ORF">CP500_019040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3 4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3 4">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RtcB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.-" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000143">
        <property type="protein sequence ID" value="PHX53891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53891">
        <property type="protein sequence ID" value="PHX53891"/>
        <property type="gene ID" value="CP500_019040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118">
        <property type="entry name" value="PTHR11118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 4" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="253"/>
            <end position="257"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="376"/>
            <end position="377"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="404"/>
            <end position="407"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="428"/>
            <end position="431"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="503"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU371113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="504" mass="54900" checksum="3DC66D83153F711F" modified="2018-01-31" version="1">MQQPKNLNRLLRALSRQGLDVSYSNKVYSISLNSSLKEHWQDASATKEVNSSLKEHWQDASATTAEVLLPEGFAVEAKALKQLANLANVRHPQGGCVCRTCATPDFHPGDSGVAIGSIVETAGMVIPAALGSDINCGMRLHVADLSIAQFLAKRDQFVELLKGDYFFGTRDVSMTAKTARAMFQHGIPGWLDAMLDKATGSVVNSDFEQLATECDRTFLGGSMNGDVKWAPAELVPNDGLVRDGGLGTIGGGNHFVEIQVVDEVLDKARAYNWGVRSGQIAFMIHSGSRNVGKYIGGMWRDWARDAWPKNLKYPESELFPLSLSANPELVHSYLQAEATAANYGFVNRLLLAELLRLRLRQVFGDIEAPLVYDLPHNITLAEGAGWVTRKGACPAYVEQPLIIPGSMGAPSYLLIGKGNDRFLRSASHGAGRARSRFDMSREGVDKSDTALGLTGVDCITLREERRIEEAPAAYKPIQPVIDAQVEAQMVDVVAKMKPVLTFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWK4</accession>
    <name>A0A2G4EWK4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Esterase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000148">
        <property type="protein sequence ID" value="PHX53858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53858">
        <property type="protein sequence ID" value="PHX53858"/>
        <property type="gene ID" value="CP500_019260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="306" mass="33920" checksum="F7A39C785DB8B4BA" modified="2018-01-31" version="1">MPKWIGKVLGVGTVTVLLLGATGYWYVFIAGAPQLDPPTIVTDVNLNFELKTYKSVAMNSQRTYGLILPPGYAKNPKQRYPVIFLLHGGHGDARAYQDKAAVTSVLHDLYKSKRLPPSIVITPDGNDQRGTSPFWDPQYFDGPNGRVGSAIGSELVSEIKSRYRTLEDPKLWAMGGQSSGGWGAFNIGLRYLNNFNILFSHSGYFTDQSGKANSPKYLVDQLSVKDRQRLRAYLDAGEGDENFLTSTQQFHEQLNSLGIANEFKKFPGGHGIVGPDVGWNYWHKHLADSLSYVGKQFNISLATQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWQ5</accession>
    <name>A0A2G4EWQ5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000136">
        <property type="protein sequence ID" value="PHX53964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53964">
        <property type="protein sequence ID" value="PHX53964"/>
        <property type="gene ID" value="CP500_018725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="199" mass="21904" checksum="E0E6E92352EA7932" modified="2018-01-31" version="1">MPYSQFTLQQVTQEFKLKIVEVSTFLPVTNPVSPSPYLTEFLERNFDLALALNTEKARSEMLICPILLAVKEALGGKISLFSGEDFTVEPETGLNGICDYILSLSSEQLFVTAPVAIIVEAKKEDLKGGLGQCVAEMVAAQKFNAAKQISIPIIYGSITTGSIWRFLKLEGQTVTIGLREYSLMPIEQILGILVSFITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWS4</accession>
    <name>A0A2G4EWS4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WYL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53984">
        <property type="protein sequence ID" value="PHX53984"/>
        <property type="gene ID" value="CP500_018595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="184"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="393" mass="45884" checksum="084484F6A12F11BD" modified="2018-01-31" version="1">MAKKPTPHPYADRLTFDRIMLLIATLVNHPGIGHSDTETSDSKYHDALLEVQSQLQKIAAEYNIEFPENYPATPTIRKDLETLRHYGILDKRMYRFGYYLGTGAMTREELLFAFQAIASQAKYQGNPQARRICEKLTKLLRGLDIELKGKLFYPVREHLNRAIIYTDPVEMLDRQEYRNTLFHKLETVETAIVRGQAIEVYRDRDYYGKGNVGFRRIWPLQLIYHDIAWYLICENCKNGHLKVERVNRFTDYCEIIDAEGRGLAAQEQSLKIAHKLLKNGWGLFLGNPEQQQAELQGTLKLQKVKVRFFQKVVGFILEGDRRHPRQKKIKEGPRDSFGNLLYVDYKIDLPDRSLNEFSLWVNRYMDSAQVLSPPSLVEKHRQAARDLCDRYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWS7</accession>
    <name>A0A2G4EWS7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Photosystem I P700 chlorophyll a apoprotein A2</fullName>
            <ecNumber evidence="20">1.97.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">PsaB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20 23" type="primary">psaB</name>
        <name evidence="23" type="ORF">CP500_018900</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="23 24" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 20">PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.</text>
    </comment>
    <comment type="function">
        <text evidence="21">PsaA and psaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>hnu + oxidized [2Fe-2S]-[ferredoxin] + reduced [plastocyanin] = oxidized [plastocyanin] + reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:30407"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10039"/>
            <dbReference type="Rhea" id="RHEA-COMP:10040"/>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <dbReference type="ChEBI" id="CHEBI:30212"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
            <dbReference type="EC" id="1.97.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <text evidence="20">PSI electron transfer chain: 5 chlorophyll a, 1 chlorophyll a', 2 phylloquinones and 3 4Fe-4S clusters. PSI core antenna: 90 chlorophyll a, 22 carotenoids, 3 phospholipids and 1 galactolipid. P700 is a chlorophyll a/chlorophyll a' dimer, A0 is one or more chlorophyll a, A1 is one or both phylloquinones and FX is a shared 4Fe-4S iron-sulfur center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="20">The PsaA/B heterodimer binds the P700 chlorophyll special pair and subsequent electron acceptors. PSI consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The cyanobacterial PSI reaction center is composed of one copy each of PsaA,B,C,D,E,F,I,J,K,L,M and X, and forms trimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="20 21">Cellular thylakoid membrane</location>
            <topology evidence="20 21">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 20 21">Belongs to the PsaA/PsaB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.97.1.12" evidence="20"/>
    <dbReference type="EMBL" id="NXIB02000140">
        <property type="protein sequence ID" value="PHX53928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53928">
        <property type="protein sequence ID" value="PHX53928"/>
        <property type="gene ID" value="CP500_018900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00482">
        <property type="entry name" value="PSI_PsaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001280">
        <property type="entry name" value="PSI_PsaA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020586">
        <property type="entry name" value="PSI_PsaA/B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036408">
        <property type="entry name" value="PSI_PsaA/B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006244">
        <property type="entry name" value="PSI_PsaB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00223">
        <property type="entry name" value="PsaA_PsaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002905">
        <property type="entry name" value="PSI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00257">
        <property type="entry name" value="PHOTSYSPSAAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81558">
        <property type="entry name" value="SSF81558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01336">
        <property type="entry name" value="psaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00419">
        <property type="entry name" value="PHOTOSYSTEM_I_PSAAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 20 21" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 20 21" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="15 20 21" id="KW-0157">Chromophore</keyword>
    <keyword evidence="13 20 21" id="KW-0249">Electron transport</keyword>
    <keyword evidence="17 20 21" id="KW-0408">Iron</keyword>
    <keyword evidence="18 20 21" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12 20 21" id="KW-0460">Magnesium</keyword>
    <keyword evidence="19 20 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 20 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 20 21" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="11 20 21" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="9 20 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 20 22" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 20 21" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="525"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="583"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="653"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="567"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="576"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="20">
        <location>
            <position position="662"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>B1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="20">
        <location>
            <position position="670"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>B3</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="678"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>B3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="679"/>
        </location>
        <ligand>
            <name>phylloquinone</name>
            <dbReference type="ChEBI" id="CHEBI:18067"/>
            <label>B</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU003775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="PHX53928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="742" mass="82868" checksum="0671C1B9BDC0E984" modified="2018-01-31" version="1">MATKFPKFSQDLAQDPTTRRIWYGIATAHDFESHDGMTEENLYQKIFASHFGHLAIIFLWTSGSLFHVAWQGNFEQWIKDPLNVRPIAHAIWDPQFGAPAVEAFTQAGASNPVDISYSGVYHWWFTQGIRTNADLYQGAIFLLFLASVFLFAGWLHLQPKYRPSLSWFKNAESRLNHHLAGLFGVSSLAWTGHMVHVAIPESRGQHVGWDNFLSTPPHPAGLAPFFTGNWGVYAENPDAASHVFGTAEGAGTAILTFLGGFHPQTESLWLTDIAHHHLAIAVLFIIAGHMYRTNFGIGHNIKEMLDSKAGLVGGKSEGQFNLPHHGLYETYNNSLHFQLGIHLAALGVITSLVAQHMYAMPPYAFIAQDHTTMAALYTHHQYIAGFIMVGAFAHGAIFLVRDYDPEANKGNVLDRVLQHKEAIISHLSWVSLFLGFHTLGLYVHNDVVVAFGTPEKQILIEPVFAQFIQAAHGKALYGMDVFLSNPDSIAATAWPNYGNVWLPGWLEGINSSTNSLFLAIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYAFPCDGPGRGGTCDVSAWDAMYLSVFWMLNTLAWVTFYWHWKHLGIWEGNVAQFNESSTYLMGWFRDYLWLYSSQLINGYNPYGTNNLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLVWAHERTPLANLVRWKDKPVALSIVQGRLVGLVHFTVGNILTFGAFVIASTAGKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWY4</accession>
    <name>A0A2G4EWY4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate/guanylate cyclase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000130">
        <property type="protein sequence ID" value="PHX54044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54044">
        <property type="protein sequence ID" value="PHX54044"/>
        <property type="gene ID" value="CP500_018285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="122"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="318" mass="35398" checksum="C15CAA885BF60F66" modified="2018-01-31" version="1">MVLRTEGGNRYLPLAGSNCWTVGRSDDNNFVLVDRWISRNHAMLQQMETGEFYLIDLGSRNGSFVNGRRVSIPVTLKNGDRLMFGQTELDFYDPTASRQLTQTHDTDSDDFTATLTVRSLISVMVMDIRDFTVLTRQLDETILSEVIGSWFRSSGHIIRKHGSWVDKYIGDAIMAVWFHKTDGVSNEEMMRICQALSQLHKATDELSSRYPLPFPLRVGAGINTGYAMVGNSGSSDRSDYTALGDTVNAAFRLESCTKQLGKDIAVGATTYKYLAKLGADNAFEQHVVDLKGYDTPTVTYGSTYAELDTFLKSSGKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX22</accession>
    <name>A0A2G4EX22_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_017965</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54084">
        <property type="protein sequence ID" value="PHX54084"/>
        <property type="gene ID" value="CP500_017965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="PHYTOCHROME_2" evidence="6">
        <location>
            <begin position="238"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="442"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="709"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="913" mass="102995" checksum="1331DDB039E10C43" modified="2018-01-31" version="1">MGTAVSLPQLIVGKQHFMQPTPLLHQYCGDFINISLVLESKLFQHIDANTRTTIILCIVAFLWSTVIGILTARWMTKPILPLHSANKNIAQSEEDKLDSSTQQLYTIFESIADIVLIVDQDKKIQIIPTKATSLYACDLNEFYLIVREFFQQKTEDIWFAKIQQALETKQTVHFDYSLRINNQEVWFAANISPLPNRSVVWVARDISDRKQAEETLQDSIQREQAITRSIDRMRQSLDMDTIFNTTTCELRQILKCDRVAIYRFNPDWSGEFVAESVAPGWISLVKRSGDRHFPDNLVEDVNCQAKNLQRPGEIILDTYIQKNEGDVYNQGLIYRIAEDIYNTGFTPCYVELLERFQARAYLIVPIFCGSQLWGLLASYQNSRPRTWHPGEINIALQISTQLGVALQQAELLEATQNQSIQLQQAALAAEAANRAKSIFLANMSHELRTPLNAILGFSQLMQHSTNLNLQDQENLRIINRSGEHLLTLINQVLDLAKIEVGRITLNPTEFALNSLLNEVEEMFQLQAQDKQLQLIFDCASDVPPYVQIDEIKLRQVLINLLSNAIKFTKEGGISVRITSVVSNENPQFPISNPQFPIPNSQSPIPHSQLHFEIEDTGCGIAPDELEKLFQAFVQTQAGASYQQGTGLGLVISQQFVKLMGGQIAVRSQVGCGTTFTFDIPVSVVDASTIKPKQVSRQVIALEPNQPLYRILIVDDRADLRQLLVKMLNRLDFELQEASNGIEAIELWANFEPHLIFMDMRMPIMDGYEATKRIKANIKGQATAIVAVSASSAEEGRTVVLSDDCDDFIRKPFREAEIFDALHKHLGVRYIYDEPQSAPELTQIAALTPKALAGLPADWLASLEQATIECDLELILTQIDQIRDRNDSLANALTALANEFLFNQILDLIKPEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX89</accession>
    <name>A0A2G4EX89_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000121">
        <property type="protein sequence ID" value="PHX54141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54141">
        <property type="protein sequence ID" value="PHX54141"/>
        <property type="gene ID" value="CP500_017735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029471">
        <property type="entry name" value="HNH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14279">
        <property type="entry name" value="HNH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="12"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="81" mass="9476" checksum="8F43460FA44295C2" modified="2018-01-31" version="1">MTKTPRIPIPPEVRKYVFTRNKYQCQSCGQTKQETQLSIDHIIPLARGGSNDISNLQTLCRTCNQQKTDKLDPRFRRHFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXD4</accession>
    <name>A0A2G4EXD4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaK</name>
        <name evidence="10" type="ORF">CP500_017710</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="6">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000121">
        <property type="protein sequence ID" value="PHX54136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54136">
        <property type="protein sequence ID" value="PHX54136"/>
        <property type="gene ID" value="CP500_017710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="624"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="520"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="624"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="6">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="697" mass="77780" checksum="4DBD4C59C8B35238" modified="2018-01-31" version="1">MGKVVGIDLGTTNSVVAVMEGGKPVVIANAEGMRTTPSVVAFTKEGERLVGQMARRQTVLNPQNTFYAVKRYIGRKYTELTPEAKRVPYTTKREENGNIKVKCPRLKKDFAPEEISAMVLRKLADEASRYLGQEVTGAVITVPAYFNDSQRQATRDAGRIAGLDVKRILNEPTAASLAYGLDRRDSQTILVFDLGGGTFDVSILDVGDGVFEVKATSGDTQLGGNDFDSKIVDWLAEQFLEKEGIDLRRNRQALQRLIEASEKAKIELSGVGVTEINLPFIDANEDGPLHLETRLTRGQFEGLCTDLVQRLRRPVKQALADANLSPSRIDEVVLVGGSTRIPLVQQIVRSLIDKEPNQNVNPDEVVAVGAAIQAGILAGDVRDVLLLDVTPLSLGLETIGGVMKKLIPRNTTIPVRRSDIFSTAENNQTVVEVHIIQGERELGRDNKSLGRFKLTGVPPAPRGIPQIQVAFDIDANGMLLVTALDKTTGREQSITVQGASTLSQQEVNEMIRDAEQFAQADKLQRERVEKRNRAEALAYQAERQLREVALDRGMQFAQRSRQRIETLIRELRDSLERNDERGVDQVGSDLQDALYDLSREVSAFAMDDDDDDFFESVKRTFAGDGSKRRTDDFSNAKPYRRSTVDPIPDRPYDQDRDRSYDRSYDRDRTPDRRSSANRPSRPYQNQSDDWDDDDDWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXD9</accession>
    <name>A0A2G4EXD9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000152">
        <property type="protein sequence ID" value="PHX53817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53817">
        <property type="protein sequence ID" value="PHX53817"/>
        <property type="gene ID" value="CP500_019425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14951">
        <property type="entry name" value="NHL-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045302">
        <property type="entry name" value="NHL2_NHL_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="546" mass="59922" checksum="93F1D5FD56028CE1" modified="2018-01-31" version="1">MPRVRAPEFPANYPWLNTDKPLSIASLKGRVVLLDFWTYCCINCLHVLPDLKYLEQKYPDSLTVIGVHSAKFDNEKEVENIRQAILRYDIEHPVIVDSDMTIWQSYAVRAWPTLMVIDPESYVIGYISGEGNRESLDELVGKLITEYKDKNAINFEALSFSLEKQRKPVSTPLAFPGKVLAFSITATEAKELDIDEALLGEMTEDSEFVDEIVEPGPANSVIQSLVGSCLFIADSGHNRIVVSTTEGEVLHVIGTGKPGLIDGDFAEAEFFAPQGMAFDAESQILYVADTENHALRKIDFTTQKVETVAGNGEQSHEIAPDGGKGLDTKLNSPWDLERVGNRLFIAMAGSHQIWEMQLDTGMIGVYAGNGRESCVDGNLAESAFSQPSGLATDRSELFVADSEISSIRAVGIDEDSQVRTVCGSGELFGFGDKDGRAEEVRLQHCLGVEYAQNYLWVADTYNHKIKRIDHRGGMCITMIGDGTAGFVDAKGLNARFFEPSGLSAIGAHLFIADTNNHVIRRVELDTLEVETLDLAGLCAPDVCVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXF6</accession>
    <name>A0A2G4EXF6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54232">
        <property type="protein sequence ID" value="PHX54232"/>
        <property type="gene ID" value="CP500_017360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="66" mass="7517" checksum="1A56AAC99F98224A" modified="2018-01-31" version="1">MKKVIGYWLLVIGYWLVVIGYWLVATKNQKLTNNLCPMPNAQCPMPNSPCPMPHAQFPISHSRYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXP6</accession>
    <name>A0A2G4EXP6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bifunctional (P)ppGpp synthetase/guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the relA/spoT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54248">
        <property type="protein sequence ID" value="PHX54248"/>
        <property type="gene ID" value="CP500_017080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045600">
        <property type="entry name" value="RelA/SpoT_AH_RIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19296">
        <property type="entry name" value="DUF5913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="3">
        <location>
            <begin position="66"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="411"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="2">
        <location>
            <begin position="681"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="758" mass="85611" checksum="5C59016E191159EB" modified="2018-01-31" version="1">MNVQTLTPSIDPAMVPDWLQECLNARSSLTPDPNLNCPTDNSLICRAFEFARDLHEGQFRKSGEPYICHPVAVAGMLRYMGANSAMIAAGFLHDIVEDTDVTAEDLEQQFGYEVRQLVEGVTKLSKFNFSSKTERQAENFRRMFLAMAKDIRVIVVKLADRLHNMRTLEHLPLEKQRSIALETREIFAPLANRLGIGRFKWELEDLAFKYLEPEAYREIQDLVAVKRSDRETQLAEVTDSLLERLDKLGIKCYEVSGRPKHLYGIYGKMQRSQKGFHQVYDIAAVRIIVETNDDCYRALAIVHDSFRPIPGRFKDYIGLPKANRYQSLHTGVIGTSGRPIEVQIRTVAMHHIAEYGIAAHWKYKETGGSSNTKVTGDDEKFTWLRQLLEWQSDLKDDREYLESIKDNLFDEDIYVFTPNGDVIALNKGSTPVDFAYRVHTEIGNHCTGARANGRMVTLDTVLKNGDIVEILTKKNGNPSLDWLNFVKTNGAKNRIRQWFKRSHRDENIARGRELLEKELGKSGFESLLKSEPMQSVALRCNYHSVEDLLAGLGYGELTLNLVLNRLQDLVKVRQKVDFPSVVATQELPVQIPVMMPPKPVPSSSPSKSPIAGVEGLLYHLSGCCCPIPGEVIIGVVTRTRGISIHRQGCVNVENVPGDRLVPVSWNASDRNGSRPNTYAVNVQIEALDRVGVFNDVLSHLKDNKVNVRSAQVKTYPGSPALIDLCMDIQDKEQFERTCMQIKNMSDILNLRRLSQVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXY2</accession>
    <name>A0A2G4EXY2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF512 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000104">
        <property type="protein sequence ID" value="PHX54392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54392">
        <property type="protein sequence ID" value="PHX54392"/>
        <property type="gene ID" value="CP500_016410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007549">
        <property type="entry name" value="DUF512"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045375">
        <property type="entry name" value="Put_radical_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04459">
        <property type="entry name" value="DUF512"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19238">
        <property type="entry name" value="Radical_SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ_6" evidence="3">
        <location>
            <begin position="11"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Radical_SAM_2" evidence="4">
        <location>
            <begin position="72"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="DUF512" evidence="2">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="DUF512" evidence="2">
        <location>
            <begin position="301"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="484" mass="54336" checksum="7A913845D0986B23" modified="2018-01-31" version="1">MSELSTRPALISKVIPDSICAEMGFDAGDAIVAINGEKPRDLIDYQFLCADEFIELEVLDNKGKTHKLEIEKEYDEDLGLEFETALFDGLIQCNNRCPFCFIDQQPPGKRETLYLKDDDYRLSFLYGSYLTLTNMSQKEWERIEQMRLSPLYVSVHATEPEVRIRLLKNLRAGKILEQIKWFQERRLQIHAQVVVCPGINDGEHLERTLLDLAKFHTGNIPAVASVAVVPVGLTRFRPAEDELIAVTPEKAREVIAQVQKIQVLLSQGKADRKRKKKSPKFTPPSPPLVRGGEDLNALLGRSKSRCIWLADEWFLIAGLDLPIASDYQDYPQIGNGVGSIRQFIQQFETAFAKLQPQPVNPQRKLTWVVGNAVEKAFEPIAHQLNQIPGLEVKMVALSSRYWGQNITVTGLLTGQDLLEALQGLDLGDGILLPSVMLKQGEPRFLDDMTLFELASLLKTEIFPVSGVEELISMAIGLVNAEVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY21</accession>
    <name>A0A2G4EY21_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54378">
        <property type="protein sequence ID" value="PHX54378"/>
        <property type="gene ID" value="CP500_016450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16377">
        <property type="entry name" value="23S_rRNA_IVP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="14125" checksum="E6FFC3106A45AB23" modified="2018-01-31" version="1">MGRPDFEELEVYKLAESLANEIWEIVKKWDYFTKDTMGKQIVRSADSVCANIAEGRGRHSDQDNRRFVKIARGSLYETVNWLRLAYARQLITSEEVNQFKPTLDKLLPKLNAYLNSIGRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYB2</accession>
    <name>A0A2G4EYB2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000120">
        <property type="protein sequence ID" value="PHX54157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54157">
        <property type="protein sequence ID" value="PHX54157"/>
        <property type="gene ID" value="CP500_017680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="285" mass="32427" checksum="5705EEA5E383E7DB" modified="2018-01-31" version="1">MMLIRNTLKLPEIELSYLEWKPESENQKVPRLLLLHGLADSAVVWTSLGNYLSNRYHIVAPDMRGHGESSKPDIGYTFESAIADLEALMVHLNWHDAHILGHSWTGKLAPIWARQNPDRFCSMILVDPIFITKLPAVLKLTLPIVYRKLDCLKCMGPFATLSEAETAAKLSGEYAGWSDVQQMVFQNQIEQKLDGTWGSKFVIAARNQIFTEVMKVAGLTEDINLPTLFIQPEKGVNRMAWQMQPYQTYLKNLVIAKVPGNHWSFLTEPETFNQTVAEFLETRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYE4</accession>
    <name>A0A2G4EYE4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54552">
        <property type="protein sequence ID" value="PHX54552"/>
        <property type="gene ID" value="CP500_015475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="377" mass="43418" checksum="7A9CC63255059907" modified="2018-01-31" version="1">MSSSTVLQNIEKHIPIVGNVHTKSPIAYRATRLAVSTVNAVQMAVAESYINGLELPDAVLRSLFDTCMPVFFKHFPSLLAPYEWVLTETDHAAEGPRDLMKIQYDLPQAMLNPMLGDSKLIYPKYSMGLWEKGATNLEQSQIHMIDDVIDKLDIRDGDHILDFGCGWGCVPNYILSKFPNVKFTGINLSHHQCEYMRHKMQDPDSYLSSGRFTLFEGDLNDAQFETKFDKILSIGVFCHVGNLTKAFQKLASFLKDNGRVFIHIITVRTPNNISSVFTHKYIFPHGRYWKYDAVPSHNKDLKTIEQWYLNGFNYSTTFANWLKNFDDSQAIVKYLDYGIDYAKFRRIWRFYLIWFVANFASCDGEYNGNGQYLMTHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYK0</accession>
    <name>A0A2G4EYK0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000093">
        <property type="protein sequence ID" value="PHX54540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54540">
        <property type="protein sequence ID" value="PHX54540"/>
        <property type="gene ID" value="CP500_015580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="12951" checksum="CE24984C54C44CFD" modified="2018-01-31" version="1">MNYTLDSLLATATKSDLVNAEAIDACTTTAWLELVALDTNVFTGDDWLALCDDIDSGEIYRDWFLWQDSEVSGDWQAYDHLSDRRFVAQGKVLIKAMIDAIENARNQAIAQLEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYN4</accession>
    <name>A0A2G4EYN4_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_016895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000110">
        <property type="protein sequence ID" value="PHX54287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54287">
        <property type="protein sequence ID" value="PHX54287"/>
        <property type="gene ID" value="CP500_016895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FHA" evidence="7">
        <location>
            <begin position="27"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="168"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="453" mass="50165" checksum="8199F55DD9479AF4" modified="2018-01-31" version="1">MTSKVTLTITAGNLKGKEFTFDTRTTCIIGRAKDCYPKIPDDEKHRTISRYHCLLDINPPDIRIRDFGSKNGTFVNSKKIGQREAHQSPEEAAHIQFPEYDLGEGDEFTLSDTSFRVAVALDPENAKTIQRQTPPTIPSNQEKLWEMLQAFLFKAVGGQNNIGVLGDYVLLKELGRGGFSLVYLARHKLTNEEVALKVMLPKVAANQRAVNWFLREVDNTKCLKHPNVVGFKKSGYADETFFFTMEYCEGGSVVDLMEKRGVSTLPIAESVGIITQVLDGLTYTHNAEIPNVRLADGSFAKGRGLIHRDLKPGNIFLANVGGKKVAKIGDYGLAKAFDQAGLSGQTMTGSQVGTPYFMPRQQVLDYKYAQPEVDVWAVAACLYVMITGYAPRNFVGLDPFRAVLDNDAVPIRDRTSSIPQPLAAVIDRALIDNPEIYYKSAVDFKQALLNTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYP5</accession>
    <name>A0A2G4EYP5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_015090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54642">
        <property type="protein sequence ID" value="PHX54642"/>
        <property type="gene ID" value="CP500_015090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011635">
        <property type="entry name" value="CARDB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07705">
        <property type="entry name" value="CARDB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19580">
        <property type="entry name" value="Exo_endo_phos_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="1451"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="1575"/>
            <end position="1679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1701"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1740"/>
            <end position="1760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1705"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1746"/>
            <end position="1760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="2028" mass="208218" checksum="7C51D3FA5E8364DA" modified="2018-01-31" version="1">MGNLYLLKSYLNKELLFLNFSVVVSVFGSEKRSQIRKKTVMAAKLVISGYMANPAGTDSPYEYLQVIATQAIDFAATPYTVVWANNGTALANGWVSGAALTYGFSLNSGSLAAGQVAYVGGSGKLINGAATTDISAANWLKTINTGTTAGDGFGTASTGPLGNGGGTPTGGADGIAIFDVPVASITSTTVPVDAVFFGSAVGIANPATGGYVLPTNDIYNNAQGTFGDGTNTTLFPDPAGGAFTKLTGTYNASTGTWTTARTGTIVSNPTALANITTGVTIATTTPLPDLTITSSAPATATVNTPFNYTLTLANSGTAAATGVSAKFTLPAGVTYNSASGTGYTVSQAGQVLTFTGTGAIDPGGSVPLTVNVTPTAAGTVTSPVGAAVADPGNTIAESNETNNSSTAAVDTNVTATANTLPTIAPSAASTFLTVPNLSGVINDPTDPAKNFGVNFTLADAETAVANLTLTATSSNTAVVPNANLTISGTGASRNLKINPVGVGYADVTVTVSDGTNTTSTVLKYAASAASGTPAVTRFLTGTSDASTAIAIDSKYMVVADDEDQNIRLYDRANSGLPVKTFNFTNSLGLTDLSGGVPREVDIEASTRVGNRIYWLGSHSNASGGNLRPNRYRLFATDISGTGATTNLTFAGKYDNLRTDLIAWGNANNFNFTASAATGKIPEATTLDGFNIEGLTLAPNGTTAYVAFRAPQVPTSDRTKALIAPITNFTDLVTGTATSATIGAPIQLDLGGRGIRSIDRNANNEYLIVAGPADSATGTAPKDFRLYTWTGNAADAPQVRSANLTALNAGGSFESIVEVPSNLTDSSQIQLLVDNGDNVWYGDNVISKELPQDNFQKFRTDTVTLGAPPVRIRNIQGASHTSSLATQTVSNVPGVVTALIATGSGRGFYMQDPTPDTGPNPNSTSEAIFVFLGSSTIPNPTVGQSVQVSGRVDEFRPANNATNLTLTQINATVTGAAVGAIASLGTITPTIIGNGGRTQPTTFIQNDFTTTGNVETGGDFDPTTEGIDFYESLESMLVQVNNPVVVGPTNEFGEFYVLPDNGTNATGRTNRGGIAVSATDFNPERIQIDDTLLNPPTNGSLSPVTNVADKLSTVTGVIGYSFSNYEILNTTQIPQASVTSGALTKEVTNLTGNATQLTVATFNVENLDPSDTAKFPAIATRIVTNLKSPDIINVEEIQDNNGATNDGVVAADTTYNTLIAAIKTAGGPTYEFRQINPVNNQDGGEPGGNIRVGFLFNPSRVTFVDRAGGTSTTATTVNTVSGEPALSASPGRIDPTNAAFNTSRKPLVGEFVFNGQSVFVIANHFNSKGGDQPLFGPNQPPVLTSETQRLQQAQIVNNFVDSILAVDANANVIVAGDLNDFAFSEPLNVVRGIPGGSGTAVLQNLIETLPENERYTYNFQGNAQVLDHILASNNLAKNLAGFDVVHINSEFADQDSDHDPSVARFNIPLPTVTITATDAAAAESAANPGIFRITRSGSTALPLTVNYTTASGTGFATSNDYTPNLTGSIIIPAGQSFTDVTITPIDDTIVEGSEAVKLTLVGAAAYNLGAAGTETATVAIADNDLAVIPIPGTFNFSNATYSVNENGTTQTIAVNRTGGINVSASVSYGTADGSATAGSDYTATSGTLNFLSGETSKTFTIPIANDTLVEGNETVNLSLSNATNNASLGNQKTAILTIVDTTATPTPTPTPTPTPTPTPTPTPTPTPTPTADLTYIGDRIERPNLDQPNPVDNTINGNSGSLIGTSKNDGYFGTNNPNIFDAKAGNDNLIGGNSADILNGNEGNDFINGYKGDDILLGGKGNDIILGGFGKDVIFGNQGNDSLNGQEDDDLILGNEGNDFIDGGKGNDTLFGGNGQDLILGSGGNDTLFGELGDDTLSGDGGDDLIYAGQGNDLIDGGKGNDSIYGDQGNDTLLGSEGNDILFGGLGNDSLIGGLDNDTFVLGNNLGLDIISDFVKGEDVLGLSSGLSFNQLEISQSNNNTLIKVSGIAIASLTGVNASQIGVNDFRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYT5</accession>
    <name>A0A2G4EYT5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Photosystem II reaction center protein Ycf12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ycf12</name>
        <name evidence="9" type="ORF">CP500_014780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A core subunit of photosystem II (PSII).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cellular thylakoid membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Ycf12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54681">
        <property type="protein sequence ID" value="PHX54681"/>
        <property type="gene ID" value="CP500_014780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01329">
        <property type="entry name" value="PSII_Ycf12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010284">
        <property type="entry name" value="PSII_Ycf12_core-subunit"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05969">
        <property type="entry name" value="PSII_Ycf12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="46" mass="4759" checksum="68BB1DD5EC86D5B4" modified="2018-01-31" version="1">MDFITDLFGGLGNVNFQLIIQVALLAAVVLSGPIVIFLLAAKGGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYW3</accession>
    <name>A0A2G4EYW3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54701">
        <property type="protein sequence ID" value="PHX54701"/>
        <property type="gene ID" value="CP500_014675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013868555" evidence="4">
        <location>
            <begin position="22"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="315"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="349"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="383"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="417"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="451"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="485"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="519"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="553"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="587"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="621"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="673" mass="75660" checksum="631BC81662A5AF03" modified="2018-01-31" version="1">MQVSNVALLTLAALASQNLMANTTNAAPAPPPAAPPQTSNFVDAVNNTALRPAQSISAPETIAYAQFSPRIAVKSQKVAIAATAQPELSATTKTNKNTSASSGDELTKYLQETWLTKLIESTTQNSPEARDTFGFLSPQADSNVESGYSFNNTVTLLNVLLILGTIFPPVTIAFFWMMRRLVVRQLVADANKRLQGIGVLESELINSSQLTQKLRDELEAQMSAAKQSVDFLSRESEISKSSVEQIETLKSQFLMHLQVLLTEVYEKKSQIVQEISQVSAVVAKESAKVAPQAQLNHSEQSEVASVASNEDNLIADDYIKQGEELYLQGKYDEAVVCFEKAILTNNNLDNAWYWRGNVLIKLERQEEAIACYDQAISIKSDHYEAWYHKAILLGKLHKYEEAIACYERASVIDRTNYAPWNNIAALLGKLQHYEEAIASYDRALAIKANDSEIWHNRGAMLGKLQQYEAAVDSYDRAIGLYPNRYQTWYNRGNMLWRLLRYVDAIASYDRAIGIAPDKYEIWYNRGAVYGRMQQYREAIASYDKAISIKSNDYELWHNRGAAFEKLSQYEAAIASYEQAIVINPKCYEAWFGKAESLTKLHRSEEAIAAYEQAIAIKPDSYDAWHHFGTVLSELKRYEEAMTAYDRAIAIKPENAQAWRDRSTLASELKQDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYX7</accession>
    <name>A0A2G4EYX7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA interferase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Toxic component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PemK/MazF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54721">
        <property type="protein sequence ID" value="PHX54721"/>
        <property type="gene ID" value="CP500_014515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR033490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12651" checksum="C7FFF901A6091E24" modified="2018-01-31" version="1">MVVYRGEIWWAQLPDPVGSEPGYRRPVLIIQDDTFTESRIRTVIVVIITSNIELAKAPGNVLLPRDATGLSRDSVVNVSQVLTVDKAFLTERIGSLPVSLQEEVDDGLRAVMYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYX8</accession>
    <name>A0A2G4EYX8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_014670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54700">
        <property type="protein sequence ID" value="PHX54700"/>
        <property type="gene ID" value="CP500_014670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calx-beta" evidence="3">
        <location>
            <begin position="258"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="3">
        <location>
            <begin position="369"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="3">
        <location>
            <begin position="510"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="743" mass="73198" checksum="9623963780245B0F" modified="2018-01-31" version="1">MANIAGTLGADLIPGNLSDGRIIDLGSLIGDDTLSGLDGNDAIGSGSGNDLVFGGPGNDIVNGNEGDDQVFGGKDDDQVFGGKGNDLVRGDIGNDSVFGNDGNDLIFGGKDNDSMFGGKGNDLILGDLGDDVLYGDLGSDTMSGGGGNDIFAIGRVGDDKPTSTTGGPGVPDADVITDFRVAGNDVIQLFGGLQFSDLQFIDGTGSNGSAIGNTIVRDTGTGEYLVNIQGKTAAELSANPAWFQSAGFPTPTPTPTPAPTPTPGTTPASVFSFSTNNYSTPEGSPATVTVIRTGNTSAPGSINFGTVDGSALSTGSATDYTATTGTLNFTAGQTSATFTVPTLNDAISEGSETVNVFLNNGNVGSLNPATVTIFDGGSAPAPTPTPITTPTPASIFQFSQGNYTVNEGGPASITVTRTGGTGAATINYATVDGSATSSGTAPDYTVAAGSLNFAAGQNSASFTVPALIDSITEGPETVNLVLSGGTVGSNPAILTINDVAPTPTPTPTPTPTPTPATTGPSIFSFSAATYSGNEGTTASVTINRTGDLTQGATILFSTADGSATGSSPDYVPVSNVSVVFAPGQASATVGVPIINDTVPELTETVNLFLSGGSIASPSAAVLSILDSSGVASNGFFYGSAPAPVADAGTGTFTINRTSGVGTGAIDFLIVAPGGGQPQNLTDYFINGSGVVPNPAGGTVNFANGQTSVSLTINNIAGLTAGSVNLGFGAGSIGTPASTSITLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYZ4</accession>
    <name>A0A2G4EYZ4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin-dependent thiol peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_014425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54734">
        <property type="protein sequence ID" value="PHX54734"/>
        <property type="gene ID" value="CP500_014425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="17360" checksum="D21EFD5260358B36" modified="2018-01-31" version="1">MILNPGDLAPDFSLPDAAGNFVHLADFLGKNIILYFYPRDNTPGCIKEACGFRDVYSDYQSRNIVVFGISTDSPQSHTKFAVKHQLPFPLLCDVDAKVSTAYGCYGLKKFMGKEFMGINRTTFAIAPDGKINKVYRKVKPQFHAIEILTDLTDISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ04</accession>
    <name>A0A2G4EZ04_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system HicB family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54741">
        <property type="protein sequence ID" value="PHX54741"/>
        <property type="gene ID" value="CP500_014465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031807">
        <property type="entry name" value="HicB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15919">
        <property type="entry name" value="HicB_lk_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HicB-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7883" checksum="B1623DBCE0FD45E3" modified="2018-01-31" version="1">MLRYEIVLYWSQEDQAFIAEVPELPGCAADGETYQEALQNIEIVMEEWIETAQELGRSIPQPKARLISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ75</accession>
    <name>A0A2G4EZ75_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flippase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_015850</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000097">
        <property type="protein sequence ID" value="PHX54487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54487">
        <property type="protein sequence ID" value="PHX54487"/>
        <property type="gene ID" value="CP500_015850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="343"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="448" mass="49661" checksum="3C9336A95331FD3F" modified="2018-01-31" version="1">MILDKIFRFIDRLSPGLRKVIANTTWLFADKILQLGMGLLVGLWVARYLQPEGFGLLNYAMATAGLFSPIANLGLNSIVIRDLSRDSSNKEEILGTAFVLKNIGSLIALFLTVGTVIILNPTEPYTQLLVGVAALLTLFQPFETINFWFQSQVQSKYTVMSANVAYLSMSAVKIVLINFRASLIAFSWVIATESALRALGAVIVYQVNGNKILRWRFSRKLAVKLLQQSWPMILSDFMIFIYMQIDQIMMKQLSSAEELGLYAAAVKVSGLWYFVPMAIVGSVFPSIVKAKDISETLYNDRLQKLLYLMALISYGVAIPVMLFAEPIVNILYGRNYVGAAPSLVVLIWAGLFVCLGIARSTWLVTEGLLHLSAATTAVGGVLNVILNLILIPRYGGLGAGIATLIAQMAASYVAHIFYPETRKMFWMQTKAIFMIGIVKEIRELLSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ78</accession>
    <name>A0A2G4EZ78_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_013920</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245955">
        <property type="entry name" value="M.Tbo703ORF13920P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54822">
        <property type="protein sequence ID" value="PHX54822"/>
        <property type="gene ID" value="CP500_013920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX54822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="430" mass="48513" checksum="7EED46A92847DD70" modified="2018-01-31" version="1">MLSSRKKRPIAVDLFAGAGGMTLGFEQAGFDVLASVEIDPIHCATHEFNFPLCSILCKDVALLTGSEIRKNSKIGKRQIDVVISGSPCQGFSLMGKRDVDDPRNSLIFHFQRLVLELKPKFFVMENVPGIKAGKHQELLNFLISSFIEAGYQVEENYQVLNAAHYGVPQSRQRLFLMGCRAGCVSPKYPPPITLLPKMSTKVHIPKRAKKSQTHPDLPVVPTVSDAIGDLPEIEKYSELLDRDWVMAEYGKCSSYANIMRGIDRSDDDYSYDRKYDRQILSSSLRTKHSLECMARFKAAKHGERDPISRFYKLHPDGVCNTLRAGTDRARGAYTSPRPIHPIAPRCITVREAARLHSYPDWFRFHITKWHGFRQVGNSVPPLLAKAVASEIIRALGVEPIKPRLKLTLGDELLLKMNWSEADQYYQITNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZE5</accession>
    <name>A0A2G4EZE5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1816 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54557">
        <property type="protein sequence ID" value="PHX54557"/>
        <property type="gene ID" value="CP500_015500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014945">
        <property type="entry name" value="DUF1816"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08846">
        <property type="entry name" value="DUF1816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="92" mass="10123" checksum="E057F152DD7BE9C4" modified="2018-01-31" version="1">MKELLISLLNFFGLAWWVEVKTSAPRCIYYFGPFMTASEAEAAKAGYVEDIENEDAQVISVLIQRCKPVNLTVADDLGKFGDGGMLPVFSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZT2</accession>
    <name>A0A2G4EZT2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase_M48 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_013060</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55005">
        <property type="protein sequence ID" value="PHX55005"/>
        <property type="gene ID" value="CP500_013060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="669"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="812"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="9">
        <location>
            <begin position="319"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="145"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="837" mass="92277" checksum="23F8C4A670E5571D" modified="2018-01-31" version="1">MASPNNQNSADSSVKQSLEAGLTALKARDYPRAIALLESVAESAADRPLGTRAQMGLVAAYKATGNLKKAIALCTSLTKNPNTQIKIWADRTLAELINRRPPKPPETPPETGFVAFEVGTELPKISPTADKPSADPKTEFVAFEQTSGQKNLKSPHIPPPPTPPKPPQVKNSEPEASTTTAPDRDSATDIPEVVTPDTYELSWRNSGRAPAGWRKLKAMKLEGLWVEAIASTIALFFLTRFILEFLLTNINSLLVQLYIFTRLPFFAPIQLFYRDPTQFIQFIFGLLLASSPWLTDALLKLICGLEPLGGITLLKSSKEANRVIRSFCKQQNMPAPMLKLLPIDVPVAFSYGCLPRFARIVVSQGLLDQLTEDEIATIVARELGHIAHWDFAPMSLAVLVMQIPYMIYWQVTYWEERLSALITIEFFRSIVKVLAAGISAGSYGIYKLLRWPMLWVSRHRVYLSDRTAAEITGNPNGLTRALAKIAIGMAKNLEQQQQTSFFLEGFDLLFPVGVREAVTLGSAGLHAPLEQILLWDVSNPFRNWLTVNSGHPLMGERLKLLALYAQFWQLEAELDLANLGTLQPTKHKFLLFNLFKSIFGAGTKSSAGTNSRAGSKFRAGTGAPPLLLQGAPFFGIPMGLAIVGVLWLIGGIFSRTSFWQLDWLWGDRSILWGCLPIGFCLGTLIRINDFFPDIPPRNIAEPSLPQILSNSETLPLDAQAVRLQGQLLGRSGMANWLGQDLILQTATGLVRLHYVSRFGPIGSLFPTPTRPSDLLGKSVVATGWLRRGANVAIDLETLRSQDGRVSHSGHPIWSAILAFAAAFWGAYIIFQGEMNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F019</accession>
    <name>A0A2G4F019_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5'-nucleotidase</fullName>
            <ecNumber evidence="3">3.1.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_012610</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55110">
        <property type="protein sequence ID" value="PHX55110"/>
        <property type="gene ID" value="CP500_012610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SurE" evidence="6">
        <location>
            <begin position="3"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="225" mass="24324" checksum="84C4D0A90CEE0347" modified="2018-01-31" version="1">MTIILTNDDGIDAPGIQALLQAVSGKTIMVAPQGQLSGCGHQVTAHSPIHVDRRSEFEYAVGGTPADCVRIALNHICPKPDLVLSGINAGGNLGVDVYISGTVAAVREAAMHGIPGVAISHWIKRPWEIDWEIATRWTSRVLADLLNREAKSGCFWNVNLPHLAPGSAEPEIVFCRPSTQPLPIEYRQEGEYFHYVGEYGKRDRALGTDVDVCFGGNIAVTEISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F026</accession>
    <name>A0A2G4F026_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55098">
        <property type="protein sequence ID" value="PHX55098"/>
        <property type="gene ID" value="CP500_012550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="219"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="407" mass="45079" checksum="0CE1D23996D06790" modified="2018-01-31" version="1">MHIAWLGKKSPFCGNVTYSREVTNALLDRGYQVSFLHFAQEAELDRNKAAWSMANGKWGTGISQSSFTHSLSPASCNEVSLPCLYKSQIYTIPTFKSSKVLMKSLRRLQPDIVHASLTLSPLDFLLPEICQELNIPLVATFHPPFDRKLRNLTSGTQHLMYQLYAPFLAHYNSTIVFSQIQRDILVKLGVPLERVAVIPNGVDAVKYSPGPSNLKSELKADRIFVYQGRIAPEKNVESLLKAWKQCNFGPGNVLAIVGDGPLAASLQQSYGEDDGIVWLGFIADEERRIEILRGADVFILPSLVEGLSLSLLEAMATGLACLATDAGADGEALERGAGVVLHTQRVRSQLQTLLPLFCDHPEMSQMLGQKARQRAIERYTLSQNITELEKLYAEILQGQRLLIRGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F071</accession>
    <name>A0A2G4F071_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55159">
        <property type="protein sequence ID" value="PHX55159"/>
        <property type="gene ID" value="CP500_012310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="26456" checksum="23306BB372D5C624" modified="2018-01-31" version="1">MMVNYTTESEKAWYKSPAIVAAVSVSTIALGAFIYPELATQPIVHYRADDNSLSADRYTLQRQTHCQISSQHYKPGDTAVSIPFADRAVVTKTISITNSLTLMGECQHNGRSITNKQPGTSLVALLERSQSTIQQQHQTNKNPGILTIVANDFEPRQGERAIDFSRVKTLVDDIEKQGVVISFIIPQGQLYENLTNELSSKESVCVLDESKDEDAVRRSMTPCIDAAFTKARKMTAKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0C7</accession>
    <name>A0A2G4F0C7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55210">
        <property type="protein sequence ID" value="PHX55210"/>
        <property type="gene ID" value="CP500_011970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="11274" checksum="BFF29FB33D991380" modified="2018-01-31" version="1">MDALVAAIAQILDYIHTQGPDAIAQLMVLLEALKAGAGYVEVGAGYVAALFGLVANVSAVIEILSQLIALISSGAGVPEIAAAIGSLAGSLGVSIEYVIHILQIIGAFLLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0H3</accession>
    <name>A0A2G4F0H3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF104 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_011815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55261">
        <property type="protein sequence ID" value="PHX55261"/>
        <property type="gene ID" value="CP500_011815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008203">
        <property type="entry name" value="AF2212-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024069">
        <property type="entry name" value="AF2212-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01954">
        <property type="entry name" value="DUF104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="11928" checksum="56E2E398BCF9E2D7" modified="2018-01-31" version="1">MPETIAAVYENGVFRPLSAVSFKDGETVQINIVADVSLEELKGDREKAIKLMDLRGLVRLPKKQGKLDPVELARREQKWRELFEELKGRPGTPVSEIVIEDRGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0N1</accession>
    <name>A0A2G4F0N1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="7">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mnmA</name>
        <name evidence="8" type="ORF">CP500_011440</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55311">
        <property type="protein sequence ID" value="PHX55311"/>
        <property type="gene ID" value="CP500_011440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="143"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="298"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="364" mass="39537" checksum="C503538ECB57DDF1" modified="2018-01-31" version="1">MNKIVVGLSGGVDSSAAAAILHHQGYEVVGLTLWLMKGKGQCCSEGMVDAAKICEQLGVPHHIVDSREVFQASIVDFLVDGYSAGITPLPCSQCNKTVKFGPMLKYAHEELGIEKIATGHYARITYNADTDRFQLRRAIDPGKDQSYFLYDLTQDLLAGTEFPLGEITKTETRKIASEFGLTTADKPESQDLCLVESNGSMRAFLDKYIAPKKGDIVHKDGRVLGQHDGVHHYTIGQRKGLGVAAPEPLYVIELDATGNRVIVGDRLLAVESECYVQKVNWVSVAQPTAPIRAQVQIRYRSQAVPATVIPLESSQAENASGVRVKLIFDEPQLSITPGQAAVWYDGDLLLGGGLIERQATEKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Q3</accession>
    <name>A0A2G4F0Q3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55354">
        <property type="protein sequence ID" value="PHX55354"/>
        <property type="gene ID" value="CP500_011180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="299"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="401" mass="45205" checksum="34A751A4E08CDFB6" modified="2018-01-31" version="1">MQSTTNQSETEPTMDAPKHGLPVTIITGFLGSGKTTLLNHILTNQQGLKTAVLVNEFGEIGIDNELIVSTDDNMVELNNGCICCTINEDLVNAVYKVLERQENLDYLVVETTGLADPLPVALTFLGTELRDLTRLDSIVTVVDAANYSLDLFNSQAAYSQIAYGDIIVLNKTDLVDEAELDLLEVKIRDVKEGARILRTVNSQVPLPLVLSVGLFESDKYFQSEETASSHAHHDHAHHDHAHHDEHEHHHAHHDHAHHDEHEHDHAHHDHAHHDHAHHDHAHHDHAHHDHSDHLQNDGFTSISFQSDKPFSLRKFQYFLDNQLPTNVFRAKGIMWFEESPKRHIFHLSGKRFSMDDTEWKGEPKNQLVLIGQGLDIEGLRSQLENCLCMPSPNRGKGFGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0V5</accession>
    <name>A0A2G4F0V5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55392">
        <property type="protein sequence ID" value="PHX55392"/>
        <property type="gene ID" value="CP500_010990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="212" mass="23692" checksum="0DC206FCF657217C" modified="2018-01-31" version="1">MSLKIYFLRHGETVYSKTGGFCGDLDPELTAEGSQMAEQFAATYAKLPWDAVYVSPMKRTIATAKPLCDTLGIEMQLRDGLREIKYGKWEGQTVEFVREKYAQEYINWLTEPAWNAPNDGETSVQIASRSSLIIAEIQEKYKDGNVLVVSHKATIRIILCSLLGIDLGSYRNRIAALAASVSIVKFDVRGPMLEVLGDRSYMDETLRNLPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1C2</accession>
    <name>A0A2G4F1C2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CP500_010240</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55561">
        <property type="protein sequence ID" value="PHX55561"/>
        <property type="gene ID" value="CP500_010240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="10">
        <location>
            <begin position="28"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="188"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="502"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="535"/>
            <end position="542"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX55561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="736" mass="81482" checksum="387DC4FEDAF547C6" modified="2018-01-31" version="1">MLKNIPFFQGISFYGKTNNSLKYQVVLQHSEEDCGAACLATIAKFYGQSLTISRLREFVGTGQQGTTLLGLKQGAEAIGLNARSVRAASAILDKLDDAPLPMIIHWKGYHWVVLYGKQGKKYVIADPGVGIRYVSKEELAASWTDWLCLLVEPDPERFFAQGDSQASASSLQRWMRRIGIYRKILMEAFLLNMVLGLLSISSPFLVQILTDDILVRGDTQLLASVAIAVIVMNLFSSSLGLVQSNLIAQFSQRLELGFVMEFARKLLRLPLSFYESRRSGEVISRLQDIQEINQLVSQVAISLPSQFFIAVVSFCFMLFYSKTLTLAATVIALLMTVSTIIFLPVLQQKTRNLLVLESETQGVLVETFKGALTVKTTGSTQQLWEEFQTRFGRLANLTFRTTQIGILNNIFSGFVGSAGSITLLWLGSGLVIEKVLSIGQLLAFISMSQNVTNFVNSLVGFSDEMTRVQTATERLSEVIDAEPESKSDTNKPFVQIQNRDDIICKSVGFHYPGRLDLLENFSVTFPGGQAIALIGYSGCGKSTLAKVIAGLYPLQSGNIRIGDYNVQDLSLDSLRQQVVLVPQEAHFWSRSILDNFRLGSPEISFELIVKACKIAGADEFISQLPDKYQTVLGEFGANISGGQRQRLAIARAIVNNPPILILDESTAGLDPASEAEVLEQLLMYRHGKTTIFISHRPRVIDRADWIIMLERGRLKVQGSAARLRSIPGDHLEFLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1D9</accession>
    <name>A0A2G4F1D9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55565">
        <property type="protein sequence ID" value="PHX55565"/>
        <property type="gene ID" value="CP500_010055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="187" mass="21312" checksum="7EC4B1F9ACFA97AB" modified="2018-01-31" version="1">MQPNDDRPLQAVPDENELLKLVDGLIFEKTGKHLNTLQRLLFQGMYDGKTYEAIARDTRYTTKYVREVGYKLLKTLSVVMDEEMQKGNLKAACDRRNISNTSNFGRDYIQYVEYVHTLNLNPCSSSPSESDNNHLTNSRFKTQIERLEIDVADVVCKLHSQGIEPCQIALVLGLSDLAIETILRELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1H8</accession>
    <name>A0A2G4F1H8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55624">
        <property type="protein sequence ID" value="PHX55624"/>
        <property type="gene ID" value="CP500_009845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="12671" checksum="0AD51FB691D4DB51" modified="2018-01-31" version="1">MARIYADEQYPLPVVEFLRPLGHDVLTVQEAGNAGLGIPDEDVLAFAVRNERAVLTLNRGDFIRLHRSQPNHAGIIICTQDSNWERQATRINDAISAEEILSGKLIRVNRPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1N1</accession>
    <name>A0A2G4F1N1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar assembly protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55649">
        <property type="protein sequence ID" value="PHX55649"/>
        <property type="gene ID" value="CP500_009560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="372" mass="41413" checksum="92B638A7DC87CF3A" modified="2018-01-31" version="1">MTKFPHDQFAKEYLQELLSPLGDVETSKDVTAEVREIDVWFQPTSFEGEYVQSLGLLGKMAATAAIIEPFRNPVTAEGIFSCVVKLLNSRAELGRRANREDRRLQERELPMLWILTPTASELLLNSLGFRIPEASEGWGRGVYFLSEAWRVGLIAIHQLPKTPETMWLRMLGRGRVQQGAIAELTEFPIDPSIRANALQLLYNLQANLQANTPTNPAGDDEDQELVMAISPLFQQHLQEAQQQGIEQGIEQGIEQGQRLILESFLQVRFGELDPISLTFVDPISALPTAEFTMLLVQLSMLPIAQIDRQPVQNLLAASVLNNRFSESGQAERSVTLIPNLLGLSPENLSLLLSELPQLSLENLIARLPNGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1P0</accession>
    <name>A0A2G4F1P0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55681">
        <property type="protein sequence ID" value="PHX55681"/>
        <property type="gene ID" value="CP500_009620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8466" checksum="ED42D10D652EFE02" modified="2018-01-31" version="1">MTAKVIPSQSIKMFRYRVHFLAKDLWKEKNPVGRMNLALQLADAASTLARLEVEEARKFQQESPSDLVSDETET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1S3</accession>
    <name>A0A2G4F1S3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mechanosensitive ion channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_009475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55714">
        <property type="protein sequence ID" value="PHX55714"/>
        <property type="gene ID" value="CP500_009475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="539" mass="61672" checksum="9F2F0A743D31354A" modified="2018-01-31" version="1">MTTISSSTFLLAILPPPGWGAFLLNFGILGIVVIVLYLLFGILRRVFRVFTSDLPLVALNVSETPLILIAVAIGLKLALVTLSVTPTSYITWFQRGLTAFLILVVAFWVVQLITEVVTYAFRQYAEGSEAMWDDVLAPILQNVIPLIVYLVGGLLFLQAFGVDIQGLLVAIGGLSFILGFALKDILANFFSGLVLLIDTPFRFGDVIELANGRRGVIKHIGLRLTELYLIDTHSQIYIPNAAFEGQNIINLSRPTNHYYYTIAIPIKADVAPALAVSMMEKVVLAHPDTMGEIHKKLELIDQFYGYSIPGVKAQQKREAGRQRLLAECEVNTILAEIEMGLAHLADIISQLERGGLDIEERRTVQAHYLELCQKIGLELKPDRHDRRRRWLTEATGTVSESSLIGLMRRWYRYWLKDPDLFQEDQQALKQEWEQKIDLLKIKVNKLFWAISNPKGLETRLDDLVESFREWLRENFKSSRNEWQDPKIWINDLNGDYTRDTLVRFYVDDIKLEHCERGQRILSEMRREIVWHLRQSYLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2D7</accession>
    <name>A0A2G4F2D7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55905">
        <property type="protein sequence ID" value="PHX55905"/>
        <property type="gene ID" value="CP500_008395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="208" mass="23206" checksum="87C0BE35FBCC8BC3" modified="2018-01-31" version="1">MNSSLDRNPVILIHGIWDTKTIFNKMSAHLTQLGWCVHSLNLTPNDGSIGLDSLAQQLADYISQTFDPKQAIDIVGYSMGGLVSRYYVQRLGGIDRVQRFITISSPHSGTLTAYSLPLPGYLDMRPNSGFLRDLHQDVTMLKRLNFTSIWTPFDVMILPSHSSKMSVGKEVKVNVLLHGQMVTDIQSINALVEELKAPIKNKIPVKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2T8</accession>
    <name>A0A2G4F2T8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Insulinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_007245</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56093">
        <property type="protein sequence ID" value="PHX56093"/>
        <property type="gene ID" value="CP500_007245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="3">
        <location>
            <begin position="28"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="4">
        <location>
            <begin position="179"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="439" mass="48300" checksum="2D6D72BF24FACC52" modified="2018-01-31" version="1">MTSTLLKPSARSPINAPTIRHFPNGLTVIAEHLPVDAVNLSIWVNLGSAVESDEINGMAHFLEHMIFKGTPSIKSGEFEAAIEQRGAVTNAATSQDYTNYYITTAPKDFAELAPLQVDVLLNASIPDDAFDRERLVVLEEIRRSEDNPGRRTYQRSVELAFESLPYRRPVLGPSSVIENLTAQQMRDFHSSRYQPSAMTAVAVGNLPVDQLIQIVADSFSAKSTAQNGNIDLAAVKIQSESQTPTYSKESPFTETIRREFVDASLQQARLMMMWRAPGFVDISETYALDVLATILGHGRTTRLVQELREDKGLVSSISVSNMTQRLGGVFSISAHLAAENLPEVEAAIIRHIRTLQTELVTDAEISRIRTQVANRFVFGNETPSDRASLYGYYQSMVGDIAPALNYTACIQALTPTQLRDAAVKYLSPDAIGVVVIRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Z7</accession>
    <name>A0A2G4F2Z7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3134 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56132">
        <property type="protein sequence ID" value="PHX56132"/>
        <property type="gene ID" value="CP500_007020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021481">
        <property type="entry name" value="DUF3134"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11332">
        <property type="entry name" value="DUF3134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="9125" checksum="34C575D26394D069" modified="2018-01-31" version="1">MYNPSLRQIPRHLPADVIPLKQQSSLLDWLESNNRLIARDVQEPDYLHEEEISELMAVDDNPYDDLEDEAEDDSATGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F302</accession>
    <name>A0A2G4F302_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3531 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56154">
        <property type="protein sequence ID" value="PHX56154"/>
        <property type="gene ID" value="CP500_006835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021920">
        <property type="entry name" value="DUF3531"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12049">
        <property type="entry name" value="DUF3531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="150" mass="17506" checksum="6A64296DE9F3724E" modified="2018-01-31" version="1">MQVKFREFNPFDLWIWLKFSNVPSNGEKQYIEEVFDSWFFLGKLGGFNAENLQVQDEGLDINDMDYDVNLADQSMMALMHNMGDIEYEGVWCRCWFDLGTSDAIGLDVLINVFQQLSKEFVTLEELIIGGENADWPVDNRRKREGFEPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F308</accession>
    <name>A0A2G4F308_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage holin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56153">
        <property type="protein sequence ID" value="PHX56153"/>
        <property type="gene ID" value="CP500_006830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007165">
        <property type="entry name" value="Phage_holin_4_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37309">
        <property type="entry name" value="PTHR37309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04020">
        <property type="entry name" value="Phage_holin_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="13254" checksum="9A11DCF5F5517677" modified="2018-01-31" version="1">MDITSLAIAWLVTSVSFFIISKLPIGVDIDSFGKAMISAAVFGLLNALVRPLFVVFSLPFVLITFGLFMIVINAAIFGLAAWLVEGFRLRWGIWSAMLGAIALGFINSILYQVLGPLLRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F323</accession>
    <name>A0A2G4F323_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56135">
        <property type="protein sequence ID" value="PHX56135"/>
        <property type="gene ID" value="CP500_007040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="371" mass="42288" checksum="9F25909F356AF8BD" modified="2018-01-31" version="1">MNISIALILDLRSIIQQTLIIKFYNAPNTSCDTISSFKAYSVTNWQSFKSYISTPKKQVAPIIGDLFNNLTHYLWDIAGFQYLDDNNLLDKIDKVLVGPYDFFNLGDVFPEIGKDKIEVFDSSLDLYKSIIENNYCAVKLVECFINQKLADRIYQTSLKKCSKLFLEEVEQSRQNFPVLWITIRSSRRIWTSQVQGIANIIKKLSVDFPNLGIIFDGWSRTEKSSKNDEVSIATEIAMMEKIIAMIPPEINTHNAIGRMTYEKAVWVHAIDLHISSLGAGMCFTVWLVNKPGVGHGNTTFTKWETHQGTAFPSCRENATEPLVSLSIDKITDEDNSFWGTRNYDCDWNAIYDEVMKIINGLSEKDKIPDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F331</accession>
    <name>A0A2G4F331_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methylthioribose-1-phosphate isomerase</fullName>
            <shortName evidence="2">M1Pi</shortName>
            <shortName evidence="2">MTR-1-P isomerase</shortName>
            <ecNumber evidence="2">5.3.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">S-methyl-5-thioribose-1-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">mtnA</name>
        <name evidence="3" type="ORF">CP500_006660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19989"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="EC" id="5.3.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56184">
        <property type="protein sequence ID" value="PHX56184"/>
        <property type="gene ID" value="CP500_006660"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00874"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01678">
        <property type="entry name" value="Salvage_MtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005251">
        <property type="entry name" value="IF-M1Pi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00512">
        <property type="entry name" value="salvage_mtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="51"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="254"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="353" mass="38225" checksum="DB1455C02C13A304" modified="2018-01-31" version="1">MTTQKSPVSPVTWLEDRVLLIDQNRLPQEYSTVEISRSDDMAEAIKTMIVRGAPAIGIAAAYGMYLGAREIETTDRAEFLAKLEQVGDLLRSTRPTAVNLFWAISRMLKTAHGAIGSVEHIQKTLLEMAKTIQAEDLQTCKDIGDKGLEVLPATPEKLTLLTHCNAGGLATAGYGTALGVVRSAWREGRLARLFADETRPRLQGAKLTTWECVQEGIPVTLIADNMAAHCMKLGMIHAVVVGADRIAANGDAANKIGTYSLAIIAKAHNVPFYVAAPLSTIDFELTDGSKIPIEERDPVEMYQVGTTRICPVGVDFYNPAFDVTPAELISGIITEHGTVAPGNLKQFQVKQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F340</accession>
    <name>A0A2G4F340_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphomannomutase/phosphoglucomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_006915</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56169">
        <property type="protein sequence ID" value="PHX56169"/>
        <property type="gene ID" value="CP500_006915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="2">
        <location>
            <begin position="8"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="3">
        <location>
            <begin position="175"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="4">
        <location>
            <begin position="284"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="508" mass="55870" checksum="B3FBF880327EC3F9" modified="2018-01-31" version="1">MQNYNWQKLQNGSDIRGIALEGVPDEKVNLTPEIATILGQSFVNWLVRKVHKPAEKLIIAIGRDSRLSGPTLMQAVMEGITSVGSLVYDFDMASTPAMFMSTITPGFDCDGAIMLTASHLPFNRNGLKFFTANGGLQKKDITDILALAESNEFEKATVSGSITKHDFISVYANQFVSKIRESVNHPDNFERPLTGLKIVVDAGNGAGGFYVDKVLKPLGADTTGSQFLEPDGTFPNHVPNPEDKQAMQSICQAVIANQADFGIIFDTDVDRSAAVDGVGKELNRNRLIALISAIVLQEHPGSTIVTDSITSDGLTQFIEQDVKGIHHRFKRGYKNVIDESIRLNQSGQESWLAIETSGHGALKENYFLDDGAYLVSKLLIELAKSKLANKSLPDLIANLQEPEESAEFRIKIGVDDFRVLGDRTIEQLQQFASTQPDWKIVPNNYEGLRISCTSASESGWFLLRLSLHDPVMPLNVESNVRGGVDRIVDRLLAFFQTTESLDLSALLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F344</accession>
    <name>A0A2G4F344_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UvrD-like helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56194">
        <property type="protein sequence ID" value="PHX56194"/>
        <property type="gene ID" value="CP500_006710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="1">
        <location>
            <begin position="5"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="59" mass="7153" checksum="76A2AEEF4EA1F19D" modified="2018-01-31" version="1">MLCYYSVSDNKLEEEKRLFYVAMTRAKRRLFISAYSRDSRGFSKFRSKFINQIPEAYIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F355</accession>
    <name>A0A2G4F355_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56203">
        <property type="protein sequence ID" value="PHX56203"/>
        <property type="gene ID" value="CP500_006755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="134" mass="15234" checksum="28FBC3CA8EE4AE50" modified="2018-01-31" version="1">MQAIQPTVTPLRRVKNSPRVAPRTSSRRRSYPHQTLAAEAGVKLTVNIVLSVCATSALIQLWPHYRAVQEKLQEIQAEVNLTEKRVNQSRSDFNRYFDPSLAKTVMQEQSNRVDPQQRAVILQESDAPEAEEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F394</accession>
    <name>A0A2G4F394_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56218">
        <property type="protein sequence ID" value="PHX56218"/>
        <property type="gene ID" value="CP500_006535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="MTs_g-TMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="2">
        <location>
            <begin position="73"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif I" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif II" evidence="1">
        <location>
            <begin position="150"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="303" mass="33654" checksum="4A028CC8E09EC97D" modified="2018-01-31" version="1">MTSTLYQQIQQFYDASSGLWEQVWGEHMHHGYYGADGNLKKERRQAQIDLIEELLDWAGLPDRKALPESYGILDVGCGIGGSTLYLTEKFSSLPGNNLSLDGEVDRVTATGITLSPVQANRATERAKIAGLESNVNFLVADALNMPFPDDSFDLVWSLESGEHMPDKIKFLQECYRVLKPGGTLILATWCHRPLGETAGELTDAERRELAEIYRVYALPYVISLPEYEEITRSLPFTNIRTADWSKAVAPFWDIVIDSALTPSAIWGLLTSGWTTIQAALALSLMSRGYQSGLIRFGLICAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3B4</accession>
    <name>A0A2G4F3B4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56273">
        <property type="protein sequence ID" value="PHX56273"/>
        <property type="gene ID" value="CP500_006310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="202" mass="22509" checksum="CC7EAF19365AEEAF" modified="2018-01-31" version="1">MARTKPIEPDAAGDKTEQILQGAMQEFLTHGYAGTSMDKVAKTGGVSKATVYSYFQDKEGLFAALIQRLAAEKLVYFPVPETEPAIALRFIATTIMDQASHEPHFLTFVRLVIAESGRFPQLAQIFVKNLAKPGIERLTQYLASCPELQLADPEATARIFIGSLVYFQLTQDMMHGQEIIPMERDRLIEGLMQLILRSESNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3H5</accession>
    <name>A0A2G4F3H5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1995 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56320">
        <property type="protein sequence ID" value="PHX56320"/>
        <property type="gene ID" value="CP500_005910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1995" evidence="1">
        <location>
            <begin position="5"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="248" mass="27565" checksum="FAB852D1B3945725" modified="2018-01-31" version="1">MTELPQDLNEAIAQSRIATAAALSDGKTLLQVELVFPEIALQAQSIAEQFLPEFEQIYSGVKVLFPDTGAAALARRDWGKTLFKVTDLGSSRTPVEDKIEPDDQLFLLINPAAVEVAQVERLYIAAGDRPVIILNPRLEDVATIGIGYAGRQLRDRFLNKIESCYYIRPLEDAALFRCYPQPWQVWLETNDEYELISETAQKPVGDDLERILAKALGTADPDSTAPAKPLKKKGFMAELQTFLKALTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3J7</accession>
    <name>A0A2G4F3J7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56329">
        <property type="protein sequence ID" value="PHX56329"/>
        <property type="gene ID" value="CP500_005965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037215">
        <property type="entry name" value="GUN4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140869">
        <property type="entry name" value="SSF140869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="12478" checksum="84E2933E96C946A8" modified="2018-01-31" version="1">MKKNNQPALILTFLLVLGLFSLAGAVVWLGLKMQSNSPTDSIAPVASANPGRPEIPEQSGDIAQKLNGVALESDRNVDYRKLRDNLQQKNWKMADRETYERLLDAALKRCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3L8</accession>
    <name>A0A2G4F3L8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56352">
        <property type="protein sequence ID" value="PHX56352"/>
        <property type="gene ID" value="CP500_005775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="218" mass="24753" checksum="A97BC95076B08469" modified="2018-01-31" version="1">MASSSAITQVLEKDIWVNATWEEFLAFADDSTWEKGKFYYYEQYMRVEMSPVGPLHGRQNSIIPYVIILFATFRNIRVVQFTNTSFRKAGIREFQPDLAYYIGADLRVPPDDSNSVVDLNIYDPPSLVVEIGASSFNDDLGGKRLLYESAGIREYWVDRANTREIFAFAINGKSSGRIENSLVLPGLEIALVEEALNRSLTQDDGEINRWLIQTFSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3N5</accession>
    <name>A0A2G4F3N5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Probable 2-phosphosulfolactate phosphatase</fullName>
            <ecNumber evidence="3 8">3.1.3.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">comB</name>
        <name evidence="9" type="ORF">CP500_005980</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23416"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15597"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58738"/>
            <dbReference type="EC" id="3.1.3.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ComB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.71" evidence="3 8"/>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56345">
        <property type="protein sequence ID" value="PHX56345"/>
        <property type="gene ID" value="CP500_005980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050532">
        <property type="term" value="F:2-phosphosulfolactate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00490">
        <property type="entry name" value="ComB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005238">
        <property type="entry name" value="ComB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036702">
        <property type="entry name" value="ComB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37311">
        <property type="entry name" value="PTHR37311"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04029">
        <property type="entry name" value="2-ph_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142823">
        <property type="entry name" value="SSF142823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="246" mass="26798" checksum="CF2114D0CC274CF1" modified="2018-01-31" version="1">MKLFIYHTPELTPTDNLPVCAIAVDVLRATTTMATALNNGAEAVQVFSDLDKLMAESEKWPADKRIRAGERGGAKVDGFDMGNSPFDCTPENIEGKRIFISTTNGTRALQRVETCRIVLTAALINRKAVVQFLLSKQPETIGIVGSGWEGSYSLEDTVCAGAIAHSLLTESGIPATDFAGNDEVFAAIALYLQWQNQLHQLLESASHGQRLLRLGVIEDLKYCAQTDILDVVPIQRELGVLVKNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3P1</accession>
    <name>A0A2G4F3P1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56366">
        <property type="protein sequence ID" value="PHX56366"/>
        <property type="gene ID" value="CP500_005855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15775" checksum="103C6F55EC4A7253" modified="2018-01-31" version="1">MPAKDIYYNNVRTALEKDGWTITNDPLPLKIGKRTLSVDLGAEKLFAAEKQGRKIAVKVKSLVSVSPVYDLEEAVGQYIVYEDILEQSEPERIIYLAIRAEVYGEIFSEPIGQVLLDKKRFKLIVFDSLKETIVRWID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3P8</accession>
    <name>A0A2G4F3P8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_005685</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56403">
        <property type="protein sequence ID" value="PHX56403"/>
        <property type="gene ID" value="CP500_005685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="112"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="439" mass="47531" checksum="B95E8611DACFC5C0" modified="2018-01-31" version="1">MNVARRRFSKLQAALFSGAIATTASISLLVPGLSQSVRAELQDSPKVVLDEAWQIVNREYVDGSFNKTDWQIARQDLLSKDYTSREAAYTALRKALEKLQDPYTRFMDPKQYEALTSQTSGELTGVGMRLEADEKTKDITVVEPMENSPAIKAGIQAGDRILVIDGKPTKGMTVADAAQIIRGAEGTKVTLRLARQGKSEFDITLTRARIEVAAVRYSLKNEAGKKVGYIRLQEFSSHAGEQMQAAIKKLSDQKADAFVLDLRGNPGGLLRVSIDIARMWMDTGAIVRTVDRAGDSQEMKANRTAITDKPVVVLVDDNSASASEILAGALKDNKRATVMGGQTFGKALVQSVHSLSDGSGLAVTIAHYYTPNGTDISHKGVTPDVKVEVTDEQKLKLANKPTLVATKDDPVYAQAIALLKTSVSSTRPVVGNEALVPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3V3</accession>
    <name>A0A2G4F3V3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_005405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56440">
        <property type="protein sequence ID" value="PHX56440"/>
        <property type="gene ID" value="CP500_005405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="179"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="416" mass="46627" checksum="CAEEBB4969FACC5F" modified="2018-01-31" version="1">MFGCQQVLIKSDQDTQAVIEYLCSESAKLSNCGIYYSRQLYFKTGRIPNRAELHKVLGTENQNLHYKAFYSDTAQQILTGVAESFKSFLGLLKGINSGTVTQHPKLPGYRQSGMALVTFTGRSVKFKDGMLRFPLGSKVKAWFGLDAFFLPMPSNLDFKAIREYRILPRNGCFYLELIYKTENIQTNVDPAKCLAIDHGIDNWLTCISNAGTSFIIDGKHLKSINQGSNKRVAFLMEGKANGYWSKRLAGLTERRNRQMRDAVNKAARKVIQHCLDNQIGTVVFGWNKGQKECANMGKKTNQKFVQIPTGRLKDRIAQLCEQYGIKFVETEESYSSKASFVDHDFLPTFGEKPEGWKASGKRVKRGLYRTAQGWLINADGNGAANIARKVAIMLGLDLGGISRGDLSAPLRLKLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3X5</accession>
    <name>A0A2G4F3X5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56435">
        <property type="protein sequence ID" value="PHX56435"/>
        <property type="gene ID" value="CP500_005370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="7256" checksum="263B1151C656352B" modified="2018-01-31" version="1">MLANSHRVLPLTSETSTRHVYHNTSVGWVERQRNPTLILEELGLAIAQPNLHYLHFTCNTNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Y1</accession>
    <name>A0A2G4F3Y1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartate aminotransferase family protein</fullName>
            <ecNumber evidence="3">2.6.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.18" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56494">
        <property type="protein sequence ID" value="PHX56494"/>
        <property type="gene ID" value="CP500_005240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016223">
        <property type="term" value="F:beta-alanine-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="434" mass="47369" checksum="74F2F399C17CA280" modified="2018-01-31" version="1">MTNMDAYWMPFTANRQFKANPRILVSAKDMHFTSDDNRSILDGTAGLWCVNAGHARETIAEAVKQQVLNLDYAPAFQMGHPAAFELAERLVKLIPGNFDRVFFTNSGSESVETALKIAIAYHRVRGEGTRQRLIGRVRGYHGVGFGGISVGGIGPNRKFFGSLLTGVDHLPHTHNLDHNAFSRKQPEWGAHLADELEGIVALHDASNIAAVIVEPLAGSTGVLIPPKGYLERLRAICDKYGILLIFDEVITGFGRLGASFATEYFGVVPDIVTAAKGITNGTVPMGAVFVKEGIYDAFMNAPENAIELFHGYTYSGHPVACAAALATLDIYEEEKLFERADKMAGYWEDAVHSFKGVRHVIDVRNLGLVAGIELESIAGKPGKRAFDCFTKCYENGLLIRTTGDIIALSPPLIIEKEHIDRIVEILTGVLQGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4N7</accession>
    <name>A0A2G4F4N7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56732">
        <property type="protein sequence ID" value="PHX56732"/>
        <property type="gene ID" value="CP500_003735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M28" evidence="1">
        <location>
            <begin position="109"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="341" mass="36764" checksum="81079B9A10D34126" modified="2018-01-31" version="1">MKQLIWIVLFIFAFGAVGWGSYSWQNLSPVPEVRSEIGISQNSSPSAFPEKLAVNFPQIDESRLWKHVTSLAGEREVDADRTFSKNYISQQLQISGFSPQLQPFDGGINVFAERKGTDSKAGAILVAAHYDTVQKSPGVDDNATGVAAVLEVARLLASRPTHRTLQVAFFDREEIGLLGSLAFTGNAGRLKDLQGVIVLDMVGYACHTSGCQRYPQGLTPKPVLDATGMTSSDKGEFIAVVGDAEHPLLLGAFAESGTTNLPPIMTLPVPLKGVLTPDVLRSDHAPFWYKGVGAVLVTDTANLRSPHYHKSTDTLATIDRVFFAGSAQIVVNATAKLLEIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Q9</accession>
    <name>A0A2G4F4Q9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56728">
        <property type="protein sequence ID" value="PHX56728"/>
        <property type="gene ID" value="CP500_003715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="170" mass="19335" checksum="D45BAD02D55B7D95" modified="2018-01-31" version="1">MSTSDNYKRQIMSDLASGDREMMPETSAQEYENFDDFAQRTSPQERKQLFGHSLNHDSLPPAQLEPELQKAIAQIKPNERDDVAREFLKHLSKRGLNDRTLEQQLGLSTHNASRMNADDVTKLASFTYHNHPDVFREVLAEQPSLMKFLGNPIVAGILGIVAAKWLTNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F526</accession>
    <name>A0A2G4F526_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KAP family P-loop domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56903">
        <property type="protein sequence ID" value="PHX56903"/>
        <property type="gene ID" value="CP500_002685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_16" evidence="1">
        <location>
            <begin position="39"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="452" mass="51083" checksum="24BF29BC0C295E10" modified="2018-01-31" version="1">MELDLQRFYKVCNPSYTLAVANPEDRQYYIEFSSVRGGKIVEQLDRTISRLSPDEPTCQLFTGHIGCGKSTELLRLQSELEHQGFHVVYFESSKDLDMADVDITDILLSVARQVSESIEKMKIKLQPTGFKALLKGVADVFQTQIDLQAEASLPGVGGINASTDGEFSLALGIGKITAKAKDSPNLRSELRQYLEPRTNVILDALNKELLEPATKELKRLGKQGLVVIIDNLDRIHLCTKPTGRLQPEYLFVDRGEQLARLNCHVVYTIPLVLIFSNDLGQLTNRFGVDPKVLPMVPVRNRDGSECFQGVELLRQMVLARAFPTVEPIARYDLIGKIFDNPETLDRLCRVSGGHVRNLLQLLYSCLQREEPPLSRATLEKVIVQRRHHLTLAIEPDEWTLLNQVSATKAVSGETKYQILLRSLWVFEYRYGDDYWFDINPILADAKELIVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F527</accession>
    <name>A0A2G4F527_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type II secretion system F family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_003315</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56839">
        <property type="protein sequence ID" value="PHX56839"/>
        <property type="gene ID" value="CP500_003315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="38"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="245"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="375" mass="40975" checksum="57352BC9BCAD6CD0" modified="2018-01-31" version="1">MATNVIGNKPKGGFSIEKIQEEIEYNFSSVTIKDLAIFARQFSAMFNAGVAIVRCLSVLQEQCSNPKLKRAIRSMNADVQEGINLAEAMAKFPDVFDQLFISMVAAGEVGGVLDESLDRLAVMMEKNHKTSSEINSAMSYPKTVFSIAIVIFFAMTIFLLPTFAKIFKDIGADLPAFTMFMLAISAFCVAWPPIQQVTTIGVIIALNIGFGMYYKTPVGHLQIDKMMMKAPIFGDLLEKSAVARFCVIFGSLTRSGVPIINSLEIVRDVAGNQAISNAIEYARQEIQGGGMISIALQEQQVFPSLAIQMIAIGEETGELDKMLMKVGAFYETEVEEAVKGLTSMLEPLMIVVVGGIVGSILLSMYLPMFAVFQKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F550</accession>
    <name>A0A2G4F550_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_002740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56914">
        <property type="protein sequence ID" value="PHX56914"/>
        <property type="gene ID" value="CP500_002740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="281" mass="30279" checksum="9EA2E816CB9067D3" modified="2018-01-31" version="1">MTAIANFLLISQTLLLQLEAGRIQAFQVAQEFSKKSLELGFEIVPKLLWAIGILLITRFAIGIVGRVTRRALSRTQATLRKFLVQAAEIAILVVGVIATLSQLGIQTTSVVAVVGAAGLAIGLAWQNTLSHFAAGVMLISLRPFEVGDAIEGGEVKGVVDSIGIFSTTLVTDDHVKIIVPNNKLFDGTLKNTTAMGTRRVDLKIDIGDRPIRPTVAELLEIAESHPLVLDNPAPTCLVAEITPDSTILSLRPWCASVAYEQVRSQIQQLVKEAMDAQKNQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F597</accession>
    <name>A0A2G4F597_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YkgJ family cysteine cluster protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56908">
        <property type="protein sequence ID" value="PHX56908"/>
        <property type="gene ID" value="CP500_002710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="14482" checksum="1D5A00A7E3448B9F" modified="2018-01-31" version="1">MATWLCVKQCGACCYLDPTERPDLDEYLSEEELAVYLSLVGDDGWCINFDKKKRECGIYAHRPRFCRVDSEVFQDMYGIEPAQLNDFAIDCCLEHIEDLYGDRSLEMIRFQQEVGTVFNQNMISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5I0</accession>
    <name>A0A2G4F5I0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56999">
        <property type="protein sequence ID" value="PHX56999"/>
        <property type="gene ID" value="CP500_002625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="14143" checksum="9348A9EEF40B3788" modified="2018-01-31" version="1">MAKINLHDGFDELAFLELFCEEPKDSQPSDGYWCYEVTDSLGVTLKFGMNIIQQSVQIELKIADATVGIMCFELVNFIEINDYINGKLEFLVAPKNEEFKTLVQVELRPRIKVDCSTLSLCPMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5L8</accession>
    <name>A0A2G4F5L8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX57001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57001">
        <property type="protein sequence ID" value="PHX57001"/>
        <property type="gene ID" value="CP500_002635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="69" mass="7807" checksum="BD151E581C7DA8B7" modified="2018-01-31" version="1">MQTQPIITEHLSPELAQIFLEGLPKTIREALSMRAKTMNYPVWAVIEMAIAGYLDEEALSFVDCKPKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5M9</accession>
    <name>A0A2G4F5M9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">UDP-glucose--tetrahydrobiopterin glucosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57049">
        <property type="protein sequence ID" value="PHX57049"/>
        <property type="gene ID" value="CP500_002365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="7050" checksum="CF8E05136794F869" modified="2018-01-31" version="1" fragment="single">HGAWGIGHGLTGFLVEPDSVNGLVGAIARIDKIDRRACRTQAEVEYSLVALGDRFEHWFNSILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5T7</accession>
    <name>A0A2G4F5T7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplW</name>
        <name evidence="7" type="synonym">rpl23</name>
        <name evidence="10" type="ORF">CP500_001805</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57154">
        <property type="protein sequence ID" value="PHX57154"/>
        <property type="gene ID" value="CP500_001805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001014">
        <property type="entry name" value="Ribosomal_L23/L25_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00050">
        <property type="entry name" value="RIBOSOMAL_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11682" checksum="B033769046738FBE" modified="2018-01-31" version="1">MSKIDPRDYADLIQRPVLTEKATRMMELNQFTFDVAPKATKPQIKAAIEELFKVKVTAVNTQNPPRKKRRVGKFVGFKPCYKRATVTLTDGDSIRKLLFPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6I3</accession>
    <name>A0A2G4F6I3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_000020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57366">
        <property type="protein sequence ID" value="PHX57366"/>
        <property type="gene ID" value="CP500_000020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="134"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="237" mass="27315" checksum="A1E2CFAD1F87C124" modified="2018-01-31" version="1">MRILLAEDEPDLGAIVQRTLSREKYLVDWVQDGTTAWNYLEDQWTEYTIAIFDWLLPGTSGLELCQRLRRQNNPLPVLMLTAKDRTEDMVAGLDAGADDYLMKPFVKAELLARLRALQRRGRSLSPEKSPHLNPAQLEVGRLRLNYTKSTISTTDDGERETVIPLTANEFRLLEYFMQHPNQILTRDRLLTRLWDVDADPMSNVVAARIRLLRRKLADYGCEGIIETVHGFGYRLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6I8</accession>
    <name>A0A2G4F6I8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57335">
        <property type="protein sequence ID" value="PHX57335"/>
        <property type="gene ID" value="CP500_000715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="37"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="217" mass="24699" checksum="0E28EE1E26778D03" modified="2018-01-31" version="1">MVTTTLTPPQQSSEEKLITLTGIKWLTFKAIMSDVGDGRAWRIAYAEGVLEIRMPLPKHERPKVMLELFIGALADELEIEAMSLGALTLEREDLARAIEPDTCFYIQNESLVRNKDEINLPIDPPPDLVVESDYTSSSLNKFSIYADLGVPEIWRYRNESLQVYQLVEGSYEKRENSLAFPFLPIAEIPDLIEQSKSIGQRAAVRLFRERVREVLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6U2</accession>
    <name>A0A2G4F6U2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CopY family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57267">
        <property type="protein sequence ID" value="PHX57267"/>
        <property type="gene ID" value="CP500_001105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="15860" checksum="5F1001D6F7AD93AE" modified="2018-01-31" version="1">MNPLPNYRPKQLSLGPLEAEILNIVWELSCATVKDVHDRILSDPDRELAYASVTTVLRRLTDKGWLVCDKTERTFVWQPLVSREQAQAIFACDRLQKFLAVGNPDIVAAFADSLDQATVEQLAEIALRIQAVRQAREEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUG3</accession>
    <name>A0A2G4EUG3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000251">
        <property type="protein sequence ID" value="PHX53179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53179">
        <property type="protein sequence ID" value="PHX53179"/>
        <property type="gene ID" value="CP500_022890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7354" checksum="BB25D32D8CA6DA95" modified="2018-01-31" version="1">MEIGNWALGIGHWALGIGHWALGMSYLLVPITHYPLPITHYPLPNFYLASAFIFSALAIASLMSPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUM7</accession>
    <name>A0A2G4EUM7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000231">
        <property type="protein sequence ID" value="PHX53243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53243">
        <property type="protein sequence ID" value="PHX53243"/>
        <property type="gene ID" value="CP500_022525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8415" checksum="234F40222E584939" modified="2018-01-31" version="1" fragment="single">SRASEIHHPISPSPRLPITPSTENETALPHEEGERKEVIPAQGWVMNSQGNVTLVGYNSGYTASGRNPRQNPVCLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUQ9</accession>
    <name>A0A2G4EUQ9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NfeD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_022425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000227">
        <property type="protein sequence ID" value="PHX53264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53264">
        <property type="protein sequence ID" value="PHX53264"/>
        <property type="gene ID" value="CP500_022425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="3">
        <location>
            <begin position="55"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="143" mass="15642" checksum="21795E9DCCB57E59" modified="2018-01-31" version="1">MIWTPTLLWLISGALLCLAELFLPTAFVAFMMGLSAFAVAAVSLFLPYVNLQIFLWMVFSTVFVLASRRLIPKGKARAIEDDKEAKTLTEIPPGEAGRVIYEGNSWRARCEDCGAAIPANQNVIVVGRKGTTLIVVPENLLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUZ8</accession>
    <name>A0A2G4EUZ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53355">
        <property type="protein sequence ID" value="PHX53355"/>
        <property type="gene ID" value="CP500_021965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014056">
        <property type="entry name" value="Addiction_killer_pred"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41791">
        <property type="entry name" value="PTHR41791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028744">
        <property type="entry name" value="Addict_mod_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02683">
        <property type="entry name" value="upstrm_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="13126" checksum="43F9EC1CFBA137F6" modified="2018-01-31" version="1">MPEVQPKEIQRYTTPDNKVPFEEWFDFLRDGKAKARIKLRLDRVLLGNLGDYRFVGEGVYELKIDYGPGYRIYFGQVGTTIILLLIGGDKSTQDRDIGQAIKYWTDYRSENNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV78</accession>
    <name>A0A2G4EV78_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_021515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000197">
        <property type="protein sequence ID" value="PHX53443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53443">
        <property type="protein sequence ID" value="PHX53443"/>
        <property type="gene ID" value="CP500_021515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="68"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="281" mass="31701" checksum="B22435AF079ECEE8" modified="2018-01-31" version="1">MTIKTRQQTNLFLLLSPATAWLIIFFILPVLIVLLYSFLERGTYGGVTWIFTLSNYQRLFSGLFWGVIARSLWLAFLTTVACLLVGYPLAFLIATRSPRWRNALLLLVIIPFWTNFLVRTYAWIILLRSEGVVNTALQSLHIISEPLNLLFTPFAVAIGLIYGYLPFMVLPLYSSIERFNFSLVEAAQDLGANDIRTFWRVFLPLTTRGIVAGSILVFVPAVGAFITPDILGGSKTMMVGNLIQNQFFKARDWPFGSALSMLLTVIVLIPVLIYFRVSDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVA0</accession>
    <name>A0A2G4EVA0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000193">
        <property type="protein sequence ID" value="PHX53472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53472">
        <property type="protein sequence ID" value="PHX53472"/>
        <property type="gene ID" value="CP500_021360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="43"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="245" mass="28606" checksum="2BFEC0DC82761E00" modified="2018-01-31" version="1">MTATILTQTLPEIIYPDSDGKPMSDNTKQFQLIVTIQGGIDALFKDNENVFVAGDLLWYPVEGDNKTRQAPDTMVIFGRPKGDRGSYQQWLEDNIAPQVVFEIISPGNRMREIFKLFKFYDNYGVEECYFYDPKDNELMGWVRSDGKLNYIESMEGWVSPRLEIRFETASGDLEIYQPDGLKFLSYVELSRQRELAQQQMELTQQQMELTQQQMEQERQEKELVQQKADRLSEKLREMGINPEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVA2</accession>
    <name>A0A2G4EVA2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TIGR00268 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000209">
        <property type="protein sequence ID" value="PHX53360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53360">
        <property type="protein sequence ID" value="PHX53360"/>
        <property type="gene ID" value="CP500_021880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01990">
        <property type="entry name" value="Alpha_ANH_like_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005232">
        <property type="entry name" value="LarE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43169:SF2">
        <property type="entry name" value="PTHR43169:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006661">
        <property type="entry name" value="PP-lp_UCP006661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00268">
        <property type="entry name" value="TIGR00268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_synthase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile and sulfur donor" evidence="1">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR006661-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="275" mass="30359" checksum="D50113C88EE2F73C" modified="2018-01-31" version="1">MLVEKLEKLTNLFAQMDRALIAYSGGIDSTLVAKIAFDVLGDRALAVTAVSPSLLPEDLEDARIQAAEIGIAHEEVETQEMANPNYTSNPVNRCYFCKSELHDTLKPLALAKGYPYVVDGVNADDLKDYRPGIVAAKERGARSPLAELGIAKFEVRQLAKELGLPWWDKPAQPCLSSRFPYGEEITVAKLQRVGRAERYLRQLGLKNLRVRSDGDTARIELPAQEIQEFVLKADLPGLVAVFQEFGFVYATLDLEGFRSGKLNQVLQPELLGAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVI0</accession>
    <name>A0A2G4EVI0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative membrane protein insertion efficiency factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be involved in insertion of integral membrane proteins into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0161 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000182">
        <property type="protein sequence ID" value="PHX53535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53535">
        <property type="protein sequence ID" value="PHX53535"/>
        <property type="gene ID" value="CP500_021000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00386">
        <property type="entry name" value="UPF0161_YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002696">
        <property type="entry name" value="Membr_insert_effic_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33383">
        <property type="entry name" value="PTHR33383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01809">
        <property type="entry name" value="YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01234">
        <property type="entry name" value="Haemolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00278">
        <property type="entry name" value="TIGR00278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8408" checksum="7ADAFEFC201C549C" modified="2018-01-31" version="1">MKIVLIGLIRGYKIGISPYLPNACRFHPTCSQYAIEAIERFGVARGGSMTIKRILRCHPLHPGGYDPVPPKDSSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVK5</accession>
    <name>A0A2G4EVK5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DUF1049 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_021325</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000193">
        <property type="protein sequence ID" value="PHX53470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53470">
        <property type="protein sequence ID" value="PHX53470"/>
        <property type="gene ID" value="CP500_021325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010445">
        <property type="entry name" value="LapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06305">
        <property type="entry name" value="LapA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="LapA_dom" evidence="7">
        <location>
            <begin position="19"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="68"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="248"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="294" mass="32121" checksum="3431803896F59B52" modified="2018-01-31" version="1">MRALFLLVTVVGLTIFALQNVDPVSLVFLGMRSPAVPLSIWILFTIGVGVVTSLLISGLLAFSNYLSQPRGRTDRQNGRNTFTEDNRTPYAASPPPRKPEIDPDRNSRNTQTQPASGYRTEYGTPTGYNARTLQQDVSPPNSGNAKTYAQAAASVPPDDDEDDWVSGGSKIDSQGSEDDWGFENESSERSAVNDVVEPNPRDYEAKQEPKSKSWTGSVYSYGYRDPSKSGVGQTESVYDADYRVIVPPQGAAIPETGGPEVAKNNSEDEEDWGLDEDDEFEDDRPSGGLINLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVN1</accession>
    <name>A0A2G4EVN1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000175">
        <property type="protein sequence ID" value="PHX53589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53589">
        <property type="protein sequence ID" value="PHX53589"/>
        <property type="gene ID" value="CP500_020670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="256" mass="28181" checksum="FD95BCDD495BD016" modified="2018-01-31" version="1">MVRYCYIVAEGPQDIEFLICFLKFYGLKRVTLLSELDSFWEPLVPKTFPINGDLMKRVPVPIFLQNADLSVALHSATGITGLSNTIEESLAIVPSSEIFGIGIFLDADDIETPQQRFEKLIPELSRLGLSLPSILGEVAKGSPRCGIFIAPNNSESGTLEDILLECAKLNYPNLFFLATDYVAGIDTNQLTKNDLKQLNKPAGKNKAVVSSISSILRPGKTLQVSIQDNRWIDENTMALDSVKLVKIFLDEVTGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVT1</accession>
    <name>A0A2G4EVT1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoate--protein ligase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000222">
        <property type="protein sequence ID" value="PHX53287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53287">
        <property type="protein sequence ID" value="PHX53287"/>
        <property type="gene ID" value="CP500_022305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="33"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="247" mass="27707" checksum="42451784B9F7AB08" modified="2018-01-31" version="1">MTNSVWRLIPLLQASGSVQMAIDQWLLEQHLAGKIGPTLRFYTWQPATISLGYHQRRWPEFWQQLSFGGLPVDLVRRPSGGRAVLHQGDLTYAVVVSGLAGSRLKAYQDICQFLIDGWREMGLDLHYGEAGRNYIHNPNCFGTATGADLVTSDGYKLIGSAQLRRGDAILQHGSMRLQPDFDLFSQVFGEELIPIKLPLFQDGNDLIETVIDVLKVAACRCFEIDLEVQPLSDEEWLEIRSIPVAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVW5</accession>
    <name>A0A2G4EVW5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH arsR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_020555</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000172">
        <property type="protein sequence ID" value="PHX53618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53618">
        <property type="protein sequence ID" value="PHX53618"/>
        <property type="gene ID" value="CP500_020555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008318">
        <property type="term" value="F:protein prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018342">
        <property type="term" value="P:protein prenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="5">
        <location>
            <begin position="282"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="471"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="505"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="539"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="573"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="607"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="641"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="675"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="709"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="743"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="777"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="811"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1038" mass="121192" checksum="8B63E2DDA08ADC73" modified="2018-01-31" version="1">MSPETLEYILVQRHTLANYLVDKIRDSATTDSKYFQLLIGPRGIGKTHLVSLIYHRVAKMEDLQDKLLIAWLREEEWGIASFLDLLRGIFRAIAQEYPAAYQVQLHDEIEKLYDLSLEQAEYKAAELLREFVGNRVLLLIVENLEDVFSGLGEFGQKQLRAYIQNHSFLTILATSQSLFDGVKGYDNPFYGFFYSHTLNEFKVDDSVDLLNHLAKLEGNNDLASFIQTPTGRDRIKVVHYLSGGSPRVYIVFSAFLMTPESLDKLVEPFMEMLDSLTPYYQDRMKYISPQQRKIVDFLCDRGGAAPVKEIAKYCFIDQRTVSSQLKDLLEKGYVKKEEIGRESWYELREPLLRFCLEVKKQRNQPIRLIVDFIRVWYTREELQQRLGLRMADVDFGEKECHFMYRQGLKPIPPDAVRDREYYMGALEAIENNEEDPLLKAYYDEMKNCREQKDDVSALAYAEKLVGSRGEARDWSEKGRCLNRLKRYDEALECLDKAIENDSNYARAWTYKGNVLNSLERYEEALVFYDKAIELDENDKLAWDWRGDVLNNLKRYEEALVSYDRAIELDANDKYAWRRLGGVLDNLKRYDEALVSYDRAIELDANYQWAWSLRGNVLDNLERYDEALVSLDRAIELDANDQYAWFLRGNVLYNLERYDEALVSLDRAIELDPNDKDIWVLRGILLYNLKRYDEALVSYDRAIELDANDQSDWFSRGIVLYNLKRYDEALVSYDRAIELDANYQWAWANRGYVLYNLKRYEEALVSYDRAIELDANDKYAWRRLGGVLDNLKRYDEALVSYDRAIELDANYQWAWSLRGNVLDNLKRYDEALESYDRAIELDANDQSDWFSRGWVLDNLGRYEEALISCDKAIELGKEGANVFFNRAIAILGLNRWDEGIAALDDAFQRLEPGDEAEADDAKLIIRNLFANTHDRTITQTRITSLIAVYEKHKYLSILGQGIVRNIPALMSEMVSDKAARTWLELWQQPTSNYEQFQIPMRLLNAAVRYKGTKGDRRVLLELPIEERNLLEPLVLGKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWA9</accession>
    <name>A0A2G4EWA9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3769 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000151">
        <property type="protein sequence ID" value="PHX53825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53825">
        <property type="protein sequence ID" value="PHX53825"/>
        <property type="gene ID" value="CP500_019390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022244">
        <property type="entry name" value="DUF3769"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12600">
        <property type="entry name" value="DUF3769"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="857" mass="92942" checksum="3EDACDE396A7E4AB" modified="2018-01-31" version="1">MPYPVPPPEPPAIIYITKPKTAALIVAASDGNTRSNSTEIPEPSPDIVLPEPTPAPEPAASAELLDPTVEAGQPTEFAAPVATFGNVIPELRFQYQEPVQETATSRTQPDSSFTTYHFVTPQNLLDSGSQKPSPEALLTQREHGEKLSQGGASSEGIGVQAKGQQQLEDKAPPEPQEIPVPEPVQETTPSGQQQLEIPTPGTAPTQGTPTAPKPKPKPAPAPGIRTAPSQRTVPFPVSPADTIEIKADRQEFDEKQQIVTAVGNVVVRFRQTVIDADRAIVNLVTRQVVASGNVAYTRGEQVVRGQQMDFNLGLNSGVVEQATGELFLPKAGSELTPTLPTDISAGTILNQPLSDRITSQQPVRGVRSPGAATFTIGGGGQGGQLAAPQITGAVNRVRFQAERLELRPDGVRVATNIRITNDPFSPPELEYRAKTATIKSISPTAQELVTTKPRLVFDNRVKIPVYPRRQVFDSQQQNGPCLTFGFDGGDRGGLYAECAFQVLETGPLRLSLTPQVYIQRAIEKHGGNPFFPDSYGLKAKLTAAVGPRTRIDGSAIFVNFDNFPNLAENAFRGNLRLRQSVGTHTLAAEYSYRDRLFNGSLGFQTVNSSLGVVLTSPIVPLGKTGINLSYQAGYQFINADTDRFDLVEPVRDNNRIDLSRLQLSAALTRDFTLWQGKALPRTPTQGLKYTRTPVVPYVKLALGLRGVGSYYSSDDLQNSLAGSVGMIGQFGHFSRPFLDYTGFNVTYTQVGRDGLSPFLFDRLVDVRILSFGLVQQVYGGFRVGIQTGINLDTKQTISTNYTLEYSRRSYAIILRFNPERQVGSLTFRISDFNWNGTPEPFGGGDVRSVEGGVRLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWG3</accession>
    <name>A0A2G4EWG3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-aminoacyl-tRNA deacylase</fullName>
            <ecNumber evidence="1">3.1.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dtd3</name>
        <name evidence="2" type="ORF">CP500_021090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-tyrosyl-tRNA(Tyr) + H2O = D-tyrosine + tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:25347"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="Rhea" id="RHEA-COMP:9872"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58570"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78723"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="1">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. DTD3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000185">
        <property type="protein sequence ID" value="PHX53517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53517">
        <property type="protein sequence ID" value="PHX53517"/>
        <property type="gene ID" value="CP500_021090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02048">
        <property type="entry name" value="Deacylase_DTD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033665">
        <property type="entry name" value="Deacylase_DTD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00010">
        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="259" mass="29172" checksum="A075AE3EFCF015C6" modified="2018-01-31" version="1">MQLIDTHVHINFDTFKSELEAIRERWRATGVVRLVHSCVEPEEFAGIQAIADRFPEVSFAVGLHPLDAGKWTDKTANLIRELASSDDRVVAIGETGLDFYKADDREHQFKVFEAQLAIAQKLDKPVIIHCRNAAAPMAQMLRDFWQTRGPVRGVMHCWGGTPEETQWFLDLGFYISFSGTVTFKKALQIHESACMVNSDRILVETDCPFLAPIPQRGKRNEPAFVYHVAEQVAKLRGVSLLTLSQQTTENACQLFGLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWK2</accession>
    <name>A0A2G4EWK2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable septum site-determining protein MinC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">minC</name>
        <name evidence="6" type="ORF">CP500_018930</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with MinD and FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MinC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000141">
        <property type="protein sequence ID" value="PHX53914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53914">
        <property type="protein sequence ID" value="PHX53914"/>
        <property type="gene ID" value="CP500_018930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901891">
        <property type="term" value="P:regulation of cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00267">
        <property type="entry name" value="MinC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013033">
        <property type="entry name" value="MinC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036145">
        <property type="entry name" value="MinC_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005526">
        <property type="entry name" value="Septum_form_inhib_MinC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34108">
        <property type="entry name" value="PTHR34108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03775">
        <property type="entry name" value="MinC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63848">
        <property type="entry name" value="SSF63848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0717">Septation</keyword>
    <feature type="domain" description="MinC_C" evidence="5">
        <location>
            <begin position="157"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="28838" checksum="8140372CE7FEF67F" modified="2018-01-31" version="1">MTPDASPGATSAPDFQGTPEVSLDMQVRLKTEDGQLLLLLPSETNTSETPTAAASTWTELWQQLKVRLNAGERFWQANAEVQLMANDRLLDIRQLQEIAEALSEVELQLKRIHTNRRQTAVAAATVGYCVEQQPPVSSLSKAPTEKPQSLAEPLYLQMTVRSGVEIRHPGTVVLLGDINPGGSIIAGGDILVWGRLRGVVHAGAGGNTKSVIMTLQMEPMVIRIAKYVARGPETSPAQFFPEVAYVTDKGIRIGRASDFDKSLLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWL0</accession>
    <name>A0A2G4EWL0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_018790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000138">
        <property type="protein sequence ID" value="PHX53942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53942">
        <property type="protein sequence ID" value="PHX53942"/>
        <property type="gene ID" value="CP500_018790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NACHT" evidence="4">
        <location>
            <begin position="375"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="892"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="927"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="969"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1011"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1059"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1094"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1136"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1178"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1220"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1262"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1304"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1346"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1388"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1430"/>
            <end position="1471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1505" mass="167173" checksum="30CA822A6B1E961C" modified="2018-01-31" version="1">MMLISLDLVISLLTAIPFGTIKDKFQRNETVIKLLKRFNLDPDAPPADFSGVYVYTLVEYGAGKPKQILELFRQPEIESAFRKAFESDSPAMLIQAGENYLNESTLGKEIRDLGIDPRREFMAFAAVFMEVAKRTRTLGDVMMGNAIASLQKRLSMVMDRIERLPTLEGIRTEFARLEAEDYPALPAAASTNIQKSQAFILSQQVRGWFETLSYKFETYQISEDNYFEWIINVPVRRNRYDRILVRGIAGEAGLRDISALRESVEKQRTDEGWLVTARRISRAARDEVEKPENRHLACYTFDELLDQDADFTAYLDWLETEITSRGIDTKYVPLACTKEEIDPDTHRKIGVSHYDGRDGWIEGYIDLWLDDPVKEHISVLGEFGTGKTWFAMHYAWMALQRYRDAQKRGLERPRLPLVIPLRDYAKAVSVESLFSEFFFRKHEIPLAGYSAFEQLNRMGKFLLIFDGFDEMAAKCDRQETINNFWELAKAVVPGAKVILTCRTEHFPEGKEGRALFNAELQASTTILTGETPQFEVLELEKFNDDQIRQALSFQTEVATVEKVMGNPQLLDLARRPVMTELILEALPDIEAGKPVDMSRIYLYAVRRKIERDIKAERTFTSLADKLYFLCELSWEMLSTDQMSLNYRGFPDRIRGLFGSIVQEEKDLDHWHYDMMGQTMLIRNADGDYTPAHRSLLEFFVAYKFAAELGVLAADFTELVAPEQSCVNPNAAPQEYTWSNYCRLQAQKRNQKELIAPLKGFVAEDLGQLRQSFGHAPLTKAVMDLLLPMVGAVPPCPPAPGLGATTERGATTGGLPLLEILEATRGKTESEVGYVGGNAATLLVKIDRTALEGKDLSHAVILGADFTNASLRRVNFAEANLTDSTFSKIFGSVRSVTFSPDGKLLATGDSDGVVRLWEASSGREILTCKGHTNVVESVAFSPDGEILASGSYDQIIKLWDVKTGECLKVLQGHTESVMSVTFNPDGNILASGSFDRTIRLWDIHTGECCKILQDHTKVVLSVAFHPAGEMLASGSGDKTVRLWNVGTGECLKILYGHKNVFSVAFNSAGEILASGSDDETVRLWNIGSGECLQILEGHFEKVRSITFSPNGEILASGSHDRTTKLWDIRTGECLNTLQGHNDRIGSVAFHPAGEILVSGSGDQTLKLWDINTGECLNTLQGHSTQVRSIAFTPNGEMLASGDDAQTVKLWDVSSGECLKILHGHLDRVDLVAFSPNGEILASGSYDETLRLWDVSSGECLHTLPEWGNQVHSIAFSPSGEILASASYNQTLKLWDVSSGQCLKTLQGHNSSVHSAAFSPLGEIFASTGYDGTVRLWDIHTGECLQILQAHTAWARAIAFSQNGEILASGSVDQTIRLWDVRSGECFQILQGHTDWISSVAFSSSSEILVSGSVDGTVRLWDISTGECLKILQGHTSRINSVAFSSNGKIIAACSRDGTIRLWDFQTGECIKILKSDRPYEEMNITGVTGLTEVEKATLKALGAVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWM8</accession>
    <name>A0A2G4EWM8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_020765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53577">
        <property type="protein sequence ID" value="PHX53577"/>
        <property type="gene ID" value="CP500_020765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="100" mass="11265" checksum="53E518DF717B4267" modified="2018-01-31" version="1">MNITKIEKNNGIALFWMFQARRNRVFSKNPVSAFLDNFRAEIGGMIAPRGVSLVSGFQVLDLSGNFQVLAGTAMIDFNNLQRALECDYSWYDQTIPDKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWN7</accession>
    <name>A0A2G4EWN7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000149">
        <property type="protein sequence ID" value="PHX53850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53850">
        <property type="protein sequence ID" value="PHX53850"/>
        <property type="gene ID" value="CP500_019300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="520" mass="57746" checksum="2BB3C340466DEE37" modified="2018-01-31" version="1">MSIFNQKINLSSLNIGQFKQPIDRIAISLILGLSLLIGLLLLSGDRTAPRVREFTWQNQQIGAEDTGFILTFFRPMNQSTVEENLKIEPDLPGKFSWAGRRMAYTLKNPAPYGVTYTLKLAGATDRYGGETNQNKGTPIQPFSASFRSRDRAFAYIGVKGETASRLMLVNLSSSDPKPIPLTPKDLVVSDFKPYPNSDRILFSATDRSQVQAGATLSQELFTVTTGINPQSASAAQPPPAGRIDKLLDSKDYQNLKFDLSADGKTIVVQRVNRRNPGDFSPWIIDEKKPPRRLENQQGGDFMIRPDNKSMVISQKQGLAIVPLQPDADPVELLPKYEQVLGMARDNSAAAYVKYNGDFTRSLFILDNQGVEQEILRIPGSIIAVYFDPRKDKDNQLGRLYCLLAERLKTEKYKEQPFIATIDLKKEGTRLVGTIKPLLILPNQLDTQISLSPDGLALIFDQSVTAATPSTAVSPRNDSGQSIATSRLWLLPLVETAADRSQPKVQPEELPFAGYHPRWLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWR1</accession>
    <name>A0A2G4EWR1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53992">
        <property type="protein sequence ID" value="PHX53992"/>
        <property type="gene ID" value="CP500_018600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="441" mass="50113" checksum="8D3721A85B828085" modified="2018-01-31" version="1">MKDLKFINKAKEIIKIALINLLFLLAFLELGSLGWYFVKHKQFFYTRQKPLDKSALGINLEGVRLNESIVERFHPFFGFVQKPSADFRPGFKVNNYGFISPYDYPFKKTNKNQFIIGVFGGSVASGYSIFEVQNKILPGYIKQLPAFKDREFVILSFATGGYKQPQQLLILNYFLALGQELDMVVNIDGFNEVALSNLNNKNKIDLAMPSLQHILPLTNLANGSLSIAAMKATIRIQENKVRINQGLASLQHCTLAVCDALTSVYIQNLVNNYKTEVLQFEKERSSQQDEGSVIYINTNKSVLEDSVAFDQMAWNWAKSSIFMNKVLSASNVPYFQVLQPNQYYQTKRVFSAAEKQIAFNKETPYARAVELGYPALFKKFPNLKKNNVDILNAVNVFDNTKDAVYVDSCCHYNQSGEVVFSNYVGSSILEGLRKEERKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWS9</accession>
    <name>A0A2G4EWS9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53979">
        <property type="protein sequence ID" value="PHX53979"/>
        <property type="gene ID" value="CP500_018565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="67" mass="7679" checksum="ECF5220104A0120C" modified="2018-01-31" version="1">MKIEDYPLAKQLIFDAEGNISQVILDYTDYQYFLEAMEDRGLLLAMGTVKNETPLNLHQALAELETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWT5</accession>
    <name>A0A2G4EWT5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxine 5'-phosphate synthase</fullName>
            <shortName evidence="2">PNP synthase</shortName>
            <ecNumber evidence="2">2.6.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pdxJ</name>
        <name evidence="3" type="ORF">CP500_020460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="EC" id="2.6.99.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homooctamer; tetramer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.99.2" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000170">
        <property type="protein sequence ID" value="PHX53627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53627">
        <property type="protein sequence ID" value="PHX53627"/>
        <property type="gene ID" value="CP500_020460"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033856">
        <property type="term" value="F:pyridoxine 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00003">
        <property type="entry name" value="PNPsynthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00279">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004569">
        <property type="entry name" value="PyrdxlP_synth_PdxJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036130">
        <property type="entry name" value="Pyridoxine-5'_phos_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30456">
        <property type="entry name" value="PTHR30456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03740">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63892">
        <property type="entry name" value="SSF63892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00559">
        <property type="entry name" value="pdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="3-amino-2-oxopropyl phosphate binding" evidence="2">
        <location>
            <begin position="214"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="240" mass="26182" checksum="25EC8C489C076D3B" modified="2018-01-31" version="1">MTKLSVNINRIALLRNSRNIGIPSVTEAAKTAIAAGAHGITVHPRPDERHIKASDVYELAKMLTVEFNIEGNPFQHPFMDLVCDVKPAQCTLVPDAPDVLTSDSGWDIPENRDRLLPIIQKLKDHGIRVSLFMDADPALMPLAKAVGADRVELYTEPYATAFREGKVASVFEQYVLAAKAAQDVGLGVNAGHDLNLQNLAKFCSIPNILEVSIGHALIAEALEMGLSETVRSYLKILSNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWU2</accession>
    <name>A0A2G4EWU2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA mismatch repair protein MutS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mutS</name>
        <name evidence="11" type="ORF">CP500_018440</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54015">
        <property type="protein sequence ID" value="PHX54015"/>
        <property type="gene ID" value="CP500_018440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00096">
        <property type="entry name" value="MutS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005748">
        <property type="entry name" value="DNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="SSF53150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="SSF55271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01070">
        <property type="entry name" value="mutS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="10">
        <location>
            <begin position="735"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="856"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="661"/>
            <end position="668"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="875" mass="97555" checksum="ABE3DEC5FCC71A5A" modified="2018-01-31" version="1">MPYTASTPTDPNQAKIRNADYRLLEFNKLTPMMQRYVEVKEQYPHALLLFRVGDFFECFFQDAVTISRELELVCTSKESGKEIGRVPMTGVPHHALDRYTSMLVEKGYAVVVCDQVEDASIAAREGRQVKREITRILTPGTLTDDGMLKPRQNNFLAAIVIAGTHWGLAYTDISTGEFVTTQADSLEQLNLELLRLQPSEVLVPTNAPDLVTMLRPGEKSEHLPDCLPSSFCYSLRSQIPFTLGEAKQRILQKFKVRSLEGMGCGHLSLAVRAAGGLLQYLEETQKGNAVPLQRLHTYTLTDFLTLDYQTRRNLEITQTVRDGVFHGSLLWAIDKTSTAMGGRALRRWVLQPLLNIKGICARHDTIQELVENNPLRQDLQQLLRQIYDIERLTGRAGSGTASARDLVALADSLGKLPELAVVAAQGRSPYLKALQNVPPILEELATKIHAHLVDEPPIHLKEGGLIRSGINSLLDEMRQTASADLDWVRNLEANERKRTGISNLKVAYNKAFGYYISISKSKVDQVPNDYTRKQTLTNEERYSTEELKEREVRILTAREDLNQLEYDIFTQVRAEIGEHAEIIRNISRAVAAVDVLCGLAEVAVYQNYCRPNMVESREIKIIEGCHPVVEKSLPPGFFVPNSAFLGREESLNRPDLIILTGPNASGKSCYLRQVGLIQLMAQMGSFVPAKAATLGICDRIFTRVGAVDDLATGQSTFMVEMNETANILNHATPKSLVLLDEIGRGTATFDGLSIAWSVAEYLANEIRARTIFATHYHELNELASILNNVANYQVTVKELPDQIVFLHQVQPGGADKSYGIEAGRLAGLPPSVIDRARQVMKQIEKHSKIAIGLRKGVKKEEKEDADGEQLDIFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX01</accession>
    <name>A0A2G4EX01_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PepSY_like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000133">
        <property type="protein sequence ID" value="PHX53996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53996">
        <property type="protein sequence ID" value="PHX53996"/>
        <property type="gene ID" value="CP500_018490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021533">
        <property type="entry name" value="PepSY-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11396">
        <property type="entry name" value="PepSY_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PepSY_like" evidence="1">
        <location>
            <begin position="87"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="182" mass="20700" checksum="7EC1B2B57486DDA3" modified="2018-01-31" version="1">MASPQLDFRRNFCNCSVQNQKPDRPKQYSPSWQTTVGLAIASTILLVGCAGEVEDSTSTTKVPDNVQRAFAAAHPNFSPAWEKQPYGYEAEFVKDGIEYEVEFSEAGQWLETEYEVTQDYQFSLLVLDKVKREHPGWALTKREVEITPQGKFYEVEIEQGGQQIELYFDERGNTAQNSNEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXI3</accession>
    <name>A0A2G4EXI3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">(Fe-S)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000114">
        <property type="protein sequence ID" value="PHX54231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54231">
        <property type="protein sequence ID" value="PHX54231"/>
        <property type="gene ID" value="CP500_017355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="210" mass="23073" checksum="32DB808DF7EACFA4" modified="2018-01-31" version="1">MYNSCKQVSEFSLEGEILSQILEDGDKLKYLRISGDRGIEYLVKLCKELRTSLSLVLTPGLRVKVAGEKQHNLKNGKIKLKAYSLKLSDSENPAQPQVHTKNTPVATLTCDRKMHSPTTSQTALHPAKTKTKILVCQKSDCQKRGGAAVCKALENALNSRGLAQQVTVQGTGCLKQCKAGPNIVVMPDKTRYSRIKPAEIPAILDKHFTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXN3</accession>
    <name>A0A2G4EXN3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000110">
        <property type="protein sequence ID" value="PHX54289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54289">
        <property type="protein sequence ID" value="PHX54289"/>
        <property type="gene ID" value="CP500_016905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="9294" checksum="59E7DDD861276ECD" modified="2018-01-31" version="1">MPTLTLTDEQVIELAQKLPDRKKHELLKLLLMQPWESWAKLTHDGPEKARQAAAQRGKDWDGMTEDEREEFIDELLHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXN7</accession>
    <name>A0A2G4EXN7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Capsular biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_017180</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54238">
        <property type="protein sequence ID" value="PHX54238"/>
        <property type="gene ID" value="CP500_017180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="AAA_31" evidence="7">
        <location>
            <begin position="584"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="207"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="383"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="784" mass="87335" checksum="DEF08A4942BD4910" modified="2018-01-31" version="1">METEQDPNLVAISSQSRQVQQFVAEEGEESGEKPQKGLNIAPLLRTFQRQALIIIAILGMAGGATVYQIKGSKKTYQGDFRILVEPVTTEARIADPSSLTNREGGVPSRDFFSLDYATQLEILQSPQMLLAITKQVQKRDPKFTEEILKKGLVVFRLGENELTKTKILEVRFLGQDPKLVEFVLQETKKKYLKYSLDERKSRIGEGVKFIEDQLPRLNKRVNDLKSELQVIQQQQRIADPKEQGTQLIVQARAIETLESDTKRLLQEQKTLYANLQKQLDFTPNEAIAASALSEEPQYKELLTKVKEVEGQIAVETARFKSANPIVEALERKRANLIGLLNKQTDRILGQNLVGAEANSKVKNFQNSIRIGLIKQLVDTANQVQVLEARNEAIIKTKDNLNRQAREFPMVARRYNEFQQELDIAARTRDQLLTQRETLGVQAAQSQIPWEIISEPQIPKGSDGKEIPVASKNTNKLMMGVIGGLVAGLGLSIIIEKLRDKFFCADDVKDAVDPPLLGAIPINKKAQKFYPSIANAYEVLESNENKYKKNASQFIEAFDSLYTNIRFLSSHRPIASLVIGSATPGEGKSTIALNLAYVAALAGQRVLLVDANLHSPSLDLLLELPNSKGLSDLLENKIEFKEAIQRSPIANNLFVLTAGIPLAGTSRRLASSQMQYLMAEFNAIFDLVIYDTPPLVDNKDANFLAARTDGILMVVSILKVKHSVVKKVFAQLENFGIPCLGTVANHLGKNKKYQPSKAPVVEDKNEYLNFSPVPSTMPKLAPKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXQ2</accession>
    <name>A0A2G4EXQ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metal ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54315">
        <property type="protein sequence ID" value="PHX54315"/>
        <property type="gene ID" value="CP500_016710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="251" mass="28069" checksum="D4F7ADFF08130A76" modified="2018-01-31" version="1">MNEISIDIENVTVAYHGKVALHSASLQLKAGTICGLVGMNGAGKSTLFKAIMGFVQPNTGRVLINGLPIRQVQKCNLVAYVPQSEEVDWNFPVNVYDVVMMGRYGYMNLLRIPRSIDKQAVRESLERVEMWDMRDRQIGELSGGQKKRTFFARALAQQGKVLLLDEPFAGVDIKTEKMMINLLMELRQTGHTILVSTHDLESITTFCDQVVLINRSILAYGNTSEVFTEENLSRTFGGSVGDFSFNKNRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXV3</accession>
    <name>A0A2G4EXV3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54351">
        <property type="protein sequence ID" value="PHX54351"/>
        <property type="gene ID" value="CP500_016665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="61"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="481" mass="52227" checksum="D7347A869948C11A" modified="2018-01-31" version="1">MSFTIQNVLIAVEGGYETADVQVADNCISALAKPSKRIAPNNSSSGNQGSETVIDGTNKLLLPGFVNAHTHSSEMWQRGIIPPLPLELWIAELYDFTPLDPEKVYLSALGTAVETLLSGGTTVVDHLVLIPGQELETIAAAVRAYQEIGIRAFIGPLIQDESLTAGMPAGENAIEHGAYIRSTQATLDLMESAIKQFHNPELGVNILLAPTGIQLCSDALFEGCIDLSDRENICRHAHLLETRAQKQLAQQKYGCSAVKHLQEIGYLSSKTSLAHCVWLDDSDIAIMAETKSTVVHNPLSNLRLGSGIAPILKYRQAGVNVSFGCDGAASNDSQDLLEAIKIGSILHNITDLDYRHWITPRQSVEMASLGGAKGLNVADEIGSLTVGKKADFVLYDLTSLSLLPRTDPIGLLILGRPTNAVDSVWVNGKRIVADGKVKTIDVDNLRQQLFEHSEWNSKRQSQTVSEIETHYRKVMNLQGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXX9</accession>
    <name>A0A2G4EXX9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000105">
        <property type="protein sequence ID" value="PHX54379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54379">
        <property type="protein sequence ID" value="PHX54379"/>
        <property type="gene ID" value="CP500_016455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="SSF101967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="6781" checksum="93BA6E41CB725D74" modified="2018-01-31" version="1">MGHWASGIGHRALGIGHWALGIGNWALGIGNWALGMGHWALGMGHRELGLFMIYSLRPIEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYA0</accession>
    <name>A0A2G4EYA0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">recA</name>
        <name evidence="11" type="ORF">CP500_015890</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the RecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000098">
        <property type="protein sequence ID" value="PHX54466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54466">
        <property type="protein sequence ID" value="PHX54466"/>
        <property type="gene ID" value="CP500_015890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="9">
        <location>
            <begin position="46"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="10">
        <location>
            <begin position="209"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="75"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX54466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="373" mass="40214" checksum="5C4FA5971AB798E2" modified="2018-01-31" version="1">MAKKDTSTKITESPEKQKALTAVLSQIERSFGKGAIVRLGDATRMRVETIPSGALTLDIALGGGLPKGRVIEIYGPESSGKTTLALHAIAEVQKSGGIAAFVDAEHALDPTYASALGVDIENLLVSQPDTGEMGLEIVDQLVRSVAVDIVVIDSVAALVPRAEIEGDMGDSHMGLQARLMSQALRKITGNIGKSGCTVIFLNQLRQKIGVTYGNPETTTGGNALKFYASVRLDIRRIQTLKKGTEEYGNRTKVKVAKNKVAPPFRIAEFDIVFGKGISTLGCLTDLADEMGVITKKGSWYSYKGDNIAQGRDKVIQHMEKNIDFKNEIEKLVREKLATGAVVSANSVAPVDDEDLEDVEDLEDEEIVEDLEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYD6</accession>
    <name>A0A2G4EYD6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000095">
        <property type="protein sequence ID" value="PHX54506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54506">
        <property type="protein sequence ID" value="PHX54506"/>
        <property type="gene ID" value="CP500_015685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="269" mass="30567" checksum="5DD6D841BD6AD4B4" modified="2018-01-31" version="1">MFQLLRQLTPQQKVQRTCAFARSVRKMAILGIESQYPNATKTKVRQEFIKRCLGFEWLEVLSDTKDWEQLVIADPIELARKIADILLPLNIPYVVGGSVASSLLGENRSTQDLDLVIDLEARIAPQLIDVMSREFYISESAVAEAITKSKISPRESSFNVIYLPSMEKVDIFVMSTDDPFSTSVMNRRQLHVVSGLKEEGIYIYSPEDIVLQKLSWYKLIPGGSQKQWRDVLGVLKVQGERLDRTYLHQWAITLKLTDLLSGALLQSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYV8</accession>
    <name>A0A2G4EYV8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000083">
        <property type="protein sequence ID" value="PHX54705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54705">
        <property type="protein sequence ID" value="PHX54705"/>
        <property type="gene ID" value="CP500_014705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="140"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="283" mass="30702" checksum="2D3575D1BEC60826" modified="2018-01-31" version="1">MIEKILLAVAGRGLCEEMFNMLMDIPSLQQTSVTVLHVVPPQVTSDGMADKLEEGGKILAKAVQSLKIDPSKVNPRLKQGDPKTTVCQVAEEEKSDLVIMGSRGFGRLQSILENSVSQYVFQLTSRPMLLVKDDIYVKKIKRVMVAIDKSESAKQYLDLAISLVKDVSGGQIILVHVTKDLTGKSTEDLTASAEKDPVLAPAIATAKKMGISYRCVSATGKPGETICRLTDELNADLLVIGSPDRRPSVAKSFVDLDRLLGNSLSDYVRVYANCPVLLARTIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYX2</accession>
    <name>A0A2G4EYX2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000081">
        <property type="protein sequence ID" value="PHX54725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54725">
        <property type="protein sequence ID" value="PHX54725"/>
        <property type="gene ID" value="CP500_014545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="90" mass="10527" checksum="EEC036D2B3C7B855" modified="2018-01-31" version="1">MTTVTAKRFSIAEYHRLGDRGFDDITMGWLLFHQLKKLKFDSNKPKSLYFLVRVGGLCLYSSGFNRRIIYARVVRNRVFSGLCDRNQVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZD2</accession>
    <name>A0A2G4EZD2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Global nitrogen regulator NtcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ntcA</name>
        <name evidence="4" type="ORF">CP500_013630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54873">
        <property type="protein sequence ID" value="PHX54873"/>
        <property type="gene ID" value="CP500_013630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018335">
        <property type="entry name" value="Tscrpt_reg_HTH_Crp-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022299">
        <property type="entry name" value="Tscrpt_reg_NtcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03697">
        <property type="entry name" value="NtcA_cyano"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00042">
        <property type="entry name" value="HTH_CRP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="26"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="141"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="221" mass="24554" checksum="E05C7DAD82C6F8BD" modified="2018-01-31" version="1">MTHDRPLAAVFRQISGGAFPPIVESFERGKTIFFPGDPAERVYVLIKGAVKLSRVYEAGEEITVALLRENSVFGVLSLITGHRSDRFYHAVAFTPVELISLPIEQVEKALKEDPELSMVMLRGLSSRILQTEMMIETLAHRDMGSRLVSFLLILCRDFGMPGSEGITIDLKLSHQAIAEAIGSTRVTVTRLLGDLRLEKMISIHKKKITVHNPVALGQQFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZD4</accession>
    <name>A0A2G4EZD4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Rrf2 family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54862">
        <property type="protein sequence ID" value="PHX54862"/>
        <property type="gene ID" value="CP500_013860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="145" mass="16547" checksum="5CE6A4250ADF014D" modified="2018-01-31" version="1">MELSSRVEYALLALLELATRRPTDSPLKVNEIAAFQEIPERYLDQILTVLRRAGFVQSVRGAKGGYLLAKQPGQINLLEVFVALEGDSSRKSQKVSESDTIEKTVVLEIWQEVRQASLSVLEKYTLEDLCEQRDDRKQVNPMYYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZE8</accession>
    <name>A0A2G4EZE8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_013890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54868">
        <property type="protein sequence ID" value="PHX54868"/>
        <property type="gene ID" value="CP500_013890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="149"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="403" mass="44883" checksum="C6AF0951856D4760" modified="2018-01-31" version="1">MKTILVIEDDYVIRENILKILKAEGFDVMGAENGMQGLSLAMSNLPDVILCDVLMPELNGYGVLMALRANPATATVPFVFLTGKADRAEIRQGMELGADDYLTKPFTKAELVGAIAIRLKKQEAFAELYNTLQIQSNEFIIQQNADEKLAQLKTSLYSALKREEFLVYYQPQISMNTGKIVGAEALVRWKHHEKGLIPPTEFIPVAEKTGFIIPLGEWILQTACKQVQAWKNDGFSGLRVAVNLSPRQFHQPDLSSRVAQILEKIGLEPSSLELELTESLMVEDVSSAIATLTQLKNLGISLSIDDFGTGYSSLSYLTQYPFDALKIDRSFVRNITDDCKNAAIVKAIIEMAHSLRLEVIAEGVETETEKDFLWRSECDVIQGYFFSPPLSAADFEKLLMEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZF1</accession>
    <name>A0A2G4EZF1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_013730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000074">
        <property type="protein sequence ID" value="PHX54891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54891">
        <property type="protein sequence ID" value="PHX54891"/>
        <property type="gene ID" value="CP500_013730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010802">
        <property type="entry name" value="DUF1400"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07176">
        <property type="entry name" value="DUF1400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013955576" evidence="2">
        <location>
            <begin position="25"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1400" evidence="3">
        <location>
            <begin position="31"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="232" mass="24762" checksum="ABE777F446C8D2D9" modified="2018-01-31" version="1">MKLTKFASIGISVFLAASASILSAHTRALGAEKVVLTFGPLRQSINVSDLEDFAKDGTTTPTIRQIIGVSKMDAGTLRGLIGLEVGLKPTNLARILYSTPGEKIVNEIGEVIRTQRNTENGKALRAAVILAASDDGKLSLLEILQRYPLAEMYVDVAQIGAAVAKVQGLAGNMQTLLQDSMRSTTTTETTTTETTVEPRRSVQPTTPPPPRPVIAPAPARIPQPARPVRGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZL5</accession>
    <name>A0A2G4EZL5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54950">
        <property type="protein sequence ID" value="PHX54950"/>
        <property type="gene ID" value="CP500_013430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="6707" checksum="0EC8A24B606A5FC9" modified="2018-01-31" version="1">MIHFEGRGKKEGVVQGTAISDIAETIIIVTPSRFLSEVEGPSCFFLLNKKAPAIKQEPFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZP3</accession>
    <name>A0A2G4EZP3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exodeoxyribonuclease 7 small subunit</fullName>
            <ecNumber evidence="3">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Exodeoxyribonuclease VII small subunit</fullName>
            <shortName evidence="3">Exonuclease VII small subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">xseB</name>
        <name evidence="4" type="ORF">CP500_013240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the XseB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54981">
        <property type="protein sequence ID" value="PHX54981"/>
        <property type="gene ID" value="CP500_013240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00337">
        <property type="entry name" value="Exonuc_7_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01280">
        <property type="entry name" value="xseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="72" mass="8300" checksum="EEA4AAAD64E49F6E" modified="2018-01-31" version="1">MIDSELDWNYEATVDRIEAIIQQVESGELALEQVFEQFSVAVECLQECESFLARGKEQMNLSIELLDDQPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZP9</accession>
    <name>A0A2G4EZP9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_013170</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54968">
        <property type="protein sequence ID" value="PHX54968"/>
        <property type="gene ID" value="CP500_013170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="124"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="124"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="225" mass="25421" checksum="806E9942CF2BBDA0" modified="2018-01-31" version="1">MKILLVEDDDRIAQALAEALTDQHYAVDIAADGQEGWNFAETFTYDLILLDLMLPKIDGITLCQRLRRQGLKTPVLMLTARDTSNDKVIGLDAGADDYVVKPFDLPELAARIRALLRRGSTTLPPVLEWENLRLNPNTCEVTYRDKLLHFTPKEYSLLELFLRTGGRVLTRSAILDHIWAFEDSPGEETVKVHLRGLRQKLKAAGAPANFIETIYGMGYRLNQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZQ7</accession>
    <name>A0A2G4EZQ7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_013300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54993">
        <property type="protein sequence ID" value="PHX54993"/>
        <property type="gene ID" value="CP500_013300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="6">
        <location>
            <begin position="7"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="5">
        <location>
            <begin position="101"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="352" mass="38626" checksum="E3E3E8B6B27E5E07" modified="2018-01-31" version="1">MSNAFRELLRKIGSGVHTGENLTRSESAAATRMMLLGEATPAQIGAFMISHRIKRPTGEELAGMLDAYEELGPKLAYPNREKGFAVSSVAVFGVAYDGRSRTAPVSPVTALILATAGVPTVMHGGDIMPTKEGIPLIEIWRGLGVDWTKLTIEKVQQVFDDTGLGFVYIPKHFPQADSLVPYRREIGKRPPFSTMELMWCPCDGDVNVISGYVHPPTEGMFIKTFELRGINNYTTIKGLEGSCDLPRDRTAIIGIAKPDAEFERVLLNHGDYGFSNTNPAFESTSELLKQMQEVLQGKPSELMQSAIWNGGFYLWRCGICSDINSGFIKAEVLLTSGQVVQKLEEVSNFVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZZ6</accession>
    <name>A0A2G4EZZ6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NfeD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_012685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55073">
        <property type="protein sequence ID" value="PHX55073"/>
        <property type="gene ID" value="CP500_012685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="3">
        <location>
            <begin position="92"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="180" mass="20619" checksum="43E9B244C7ECB7BF" modified="2018-01-31" version="1">MYSILSLSLALATNQPTFAFTPPILWLIVGVVLSAIDLFIQKTQPQKYRFYVLMMGASALIESFILWRGAIAFNFSWANVMYEDFDWQIFYWMGISLALTIWIRPIFIVRKKFVIPEATEATTISEIFPGETGMVIYEGASWKARNEDSQGIAPRQKVYVLRREGNTLIVVPDKLIHINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F038</accession>
    <name>A0A2G4F038_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54807">
        <property type="protein sequence ID" value="PHX54807"/>
        <property type="gene ID" value="CP500_014165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="105" mass="12026" checksum="112983051F869D48" modified="2018-01-31" version="1">MSIAVIKEHIEITPGICGGKPRIAGHRIRVQDIVVWHEQMGMSPDEILYHYPSITLSDIYAALAYYHDRRDEIRSAMEADAEFARQLKAQTPSLLQEKLKNRQHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F059</accession>
    <name>A0A2G4F059_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Ribonuclease H</fullName>
            <shortName evidence="5">RNase H</shortName>
            <ecNumber evidence="4 5">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rnhA</name>
        <name evidence="7" type="ORF">CP500_012185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4 5"/>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55136">
        <property type="protein sequence ID" value="PHX55136"/>
        <property type="gene ID" value="CP500_012185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09278">
        <property type="entry name" value="RNase_HI_prokaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00042">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022892">
        <property type="entry name" value="RNaseHI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="6">
        <location>
            <begin position="3"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="32867" checksum="1D5E069144216135" modified="2018-01-31" version="1">MTLPQIKSLYTDGACSGNPGPGGWGAVVCFADGNCHELGGGAPQSTNNRMEMQAAIAALEFFANSGQTEPVTLYTDSEYVKNGITKWIQGWKNKGWKTSAGKDVVNQDLWHLLDKLNSRQVKWEHVRGHSGDFYNDRCDEIARSFSHNLVPELQQQKGVGAGTGAVPLQSENTIVSEETETNGNKTIESYVITSDLLISNAAMMDSTADTLENLPREVRVQELRNLIETLHIADEVATKGYLITSSELADLMDVNASAVTSRGDNWVWRNWVVSRVRREGNQILWQLERIDHVSTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F094</accession>
    <name>A0A2G4F094_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55176">
        <property type="protein sequence ID" value="PHX55176"/>
        <property type="gene ID" value="CP500_012395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="318" mass="36317" checksum="FF9C4A98DCF7FE3D" modified="2018-01-31" version="1">MVGSRERIEQDLAALDESLTAFDLEFRSTYESYLTALGQAVRQQLILASYHLCTQVMPDAFLKLSFNERQKMQHSVRLLAAISQEKLRSLATQEQAVETIEEDLEEDLEEDDDDDEIEEYDEMAEYENRQEDDNIDDNRDIEEQEDSIIHYQFPAKNHELPLPTNSPETLARWQRHLEKAIFNIIKLLSRDTNRLLQQSGILPNQLPQQILEAAYQAESSGESVAGPPNLLNIIIETGTSSKSGKLGETRGNTAIQITAIKLRLSEIEFADAATSAGRQQIRNLSMRLNTLGRDYQKKQRELAVVQAESAWRSSWFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F098</accession>
    <name>A0A2G4F098_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_012040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000062">
        <property type="protein sequence ID" value="PHX55185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55185">
        <property type="protein sequence ID" value="PHX55185"/>
        <property type="gene ID" value="CP500_012040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="266" mass="28523" checksum="2E25A061DE0E4EF7" modified="2018-01-31" version="1">MLVMISNIVAIYRKELQSYFASPLAYAIAAVFWLITGYFLIAILLAPDGLIPQITQRDQAGITEPPIDVAYEFLQLFLRIMGSLSLFVLPALSMGLYAEERKRGTLELLATSPLTNWAVATGKLLGVLTFYTTMLLPLLACEAIALSSSTPPVPPAVLLLGHGGLILLAAAVLSLGMFISSLTDSTILSAILTFALVLFLWVIDAAAVGIGGPFGSALGQLSLLTHYTNLVKGVFDTSSLIMFASYIILGVFLTAQSIDTLRYQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0H0</accession>
    <name>A0A2G4F0H0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="13">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="13">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pheS</name>
        <name evidence="15" type="ORF">CP500_011805</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="13"/>
    <dbReference type="EMBL" id="NXIB02000059">
        <property type="protein sequence ID" value="PHX55259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55259">
        <property type="protein sequence ID" value="PHX55259"/>
        <property type="gene ID" value="CP500_011805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="14">
        <location>
            <begin position="126"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="PHX55259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="334" mass="37440" checksum="EDA374F6C9D56354" modified="2018-01-31" version="1">MTVQLSDIETQLETLGQEAKSAIATTDTLEQLEQLRVNYLGKKGQLSQVLGMMGKLAPDQRPKLGAIANTVKEALQTDLEDKRAALQTAQIQAKLASETLDVTMPGIFSPQGRIHPLNSVIDRALDIFVGLGYTVANGPEMETDYYNFEALNTPPDHPARDMQDTFYLPGGNLLRTQTSSVQIRYMEQHKPPIRIVSPGRVYRRDTVDATHAAVFHQIELLAIDEGLTFTDLKGTIKEFLRQMFGQDLPIRFRTSYFPFTEPSAEVDLQWNGKWLEVLGCGMVDPNVLKGVGLDPEKYSGFAAGFGVERFAMVLHEIDDIRRVYASDLRFLRQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0J4</accession>
    <name>A0A2G4F0J4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55275">
        <property type="protein sequence ID" value="PHX55275"/>
        <property type="gene ID" value="CP500_011550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="306" mass="32391" checksum="82884A41CDC035CF" modified="2018-01-31" version="1">MEINQNPLEFLTAKVQETVAETQNLAHQIAANVEETATVVTTFIQSAPSSIVSAGAIATQEAFKVAHNIRFENLPTTLQFKFATVGVRDGIRNIQEAAKVFESIPAQIRAQGPEAIRNFRQGKDWSHIQAHVNGGGSEAANGIFEHFRVNRVRGGVDMTAAELAVAKQVLADAAFKAAVAEVVGAALKGAIAAAVIELVFSILENSLLCVEGKITQSELVEQVATATAKAGIAGGVITAILLTLCMIFPPIAALLGATTIPLAIAGIGFMGIRAWEIFCHGDRIFGITEQTQKFLGMTEATTEVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0K3</accession>
    <name>A0A2G4F0K3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heme oxygenase (biliverdin-producing)</fullName>
            <ecNumber evidence="2">1.14.14.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_011515</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heme oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.18" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55268">
        <property type="protein sequence ID" value="PHX55268"/>
        <property type="gene ID" value="CP500_011515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004392">
        <property type="term" value="F:heme oxygenase (decyclizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006788">
        <property type="term" value="P:heme oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19165">
        <property type="entry name" value="HemeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002051">
        <property type="entry name" value="Haem_Oase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016053">
        <property type="entry name" value="Haem_Oase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018207">
        <property type="entry name" value="Haem_oxygenase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720">
        <property type="entry name" value="PTHR10720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01126">
        <property type="entry name" value="Heme_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000343">
        <property type="entry name" value="Haem_Oase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00088">
        <property type="entry name" value="HAEMOXYGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00593">
        <property type="entry name" value="HEME_OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000343-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000343-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="26900" checksum="30A2CF2D06C17EB6" modified="2018-01-31" version="1">MSINLATKLREGTKKSHTMAENVGFVKCFLKGVVEKTSYRKLVANLYFVYSAIEEEMERQKQHPVVSKIYFSQLNRKQSLEQDLLYYHGTNWREQVVPSDAAKAYVQRIHDISASAPELLVAHSYTRYLGDLSGGQILKGIAQRGMNLTDGEGTAFYEFADIPDEKEFKTNYRQAMNELPIDEATAERIVDEANSAFGMNMKMFMELEGNLIKAVGQMLFNTLTRKRGAASTELATAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0V6</accession>
    <name>A0A2G4F0V6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_012755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="245951">
        <property type="entry name" value="M.Tbo703ORF12755P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55087">
        <property type="protein sequence ID" value="PHX55087"/>
        <property type="gene ID" value="CP500_012755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="430" mass="48509" checksum="877EC12E3F04151C" modified="2018-01-31" version="1">MQKIRFIDLFSGIGGMRLAFESAASSLNLQTECVLSSEINPDAQLVYKTNFCDTPSGDIRLIDQLPEHQILLAGFPCQSFSYAGKKAGFGDTRGTLFFEIVRLIDTFKPQAFIFENVRGLVSHDSGQTLETIKGEMTDRGYSFDYFVLNSSNFSLPQNRVRVYLVGILNAVPKFNLISDLGPKDSHSSNHQQLLLFYPLSQPVTVADILEDNPDPKYDCSPGFVQALKQIVNQDLNRLHGMRLIDYRGGNSIHSWELGLRGECSLDEIELMNLFILKRRNKEFGHHQDGKLLTKEQIATFFDHPNLTEILDSLVTKKYLQRNNQLYKPVSGNFSFEVYKFLDPAKISVTVVASDANRLGVYHNHRVRRITPREAARLQGFPDSFILHSNDDKAYHQIGNSVSVNVVTTIAEEVIQNVLYSAKSVCFKNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0X8</accession>
    <name>A0A2G4F0X8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GntR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55411">
        <property type="protein sequence ID" value="PHX55411"/>
        <property type="gene ID" value="CP500_011105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="327" mass="36150" checksum="B64179B316BE466F" modified="2018-01-31" version="1">MVQFHIQTDSDIPASTQLFNQIRFAIASRQFPPGHRLPSTRQLAMQTGLHRNTISKVYRQLENTGLVEAQAGSGIYVRAQGHEGGSKLKSPILDEYPLANKIVQESLDQMLGQGCTLNQARELFLAEIDWRLRCSARVVVTAPAEDIGVGELMARELEQALRIPIQLVPMEELATFLDQISSGTVITSRYFIGQAESIAAPRSVRVIPVDIYDYVQEIKLVGNLPKDSYLGLVSLSPGMLRSTEVIIHSFRGEDLLVMTALISDSYKINSIVRSARTIFCDQPSFATVKAAINAAREDIIRPPQLICSENYIGAKSINLLKRELGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F111</accession>
    <name>A0A2G4F111_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Porphobilinogen deaminase</fullName>
            <shortName evidence="6">PBG</shortName>
            <ecNumber evidence="6">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Hydroxymethylbilane synthase</fullName>
            <shortName evidence="6">HMBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hemC</name>
        <name evidence="9" type="ORF">CP500_012240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
        <text evidence="6">Binds 1 dipyrromethane group covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">The porphobilinogen subunits are added to the dipyrromethane group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the HMBS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55147">
        <property type="protein sequence ID" value="PHX55147"/>
        <property type="gene ID" value="CP500_012240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018160">
        <property type="term" value="P:peptidyl-pyrromethane cofactor linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="7">
        <location>
            <begin position="12"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobil_deamC" evidence="8">
        <location>
            <begin position="235"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="modified residue" description="S-(dipyrrolylmethanemethyl)cysteine" evidence="6">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="323" mass="35315" checksum="B0E36800AFFA3809" modified="2018-01-31" version="1">MSTTASAPSRTVRIGSRKSQLALVQTHWVQAELQKHFPQHTFEVHTMSTQGDIILDVALAKIGDKGLFTKELETGMLNNETDFAVHSLKDLPTNLPEGLMLGCVTERENPADALVVHEKHKDKQLDTLPKGAVIGTSSLRRLAQLRHHFPHFEFKDIRGNLNTRLAKLDDGGYDAIILAFAGLERLGMGDRIHQVIAPEISLHAVGQGALGIECRAGDPEILEIIKALEHSETAQRCYAERAFLRELEGGCQVPIGVNTKIEDGQLTLTGMVSSLDGQRFVKDTVSGGADTAELLGIDLAHRLRAQGASEILEEIFIEVQRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F120</accession>
    <name>A0A2G4F120_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF3488 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_010715</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55445">
        <property type="protein sequence ID" value="PHX55445"/>
        <property type="gene ID" value="CP500_010715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021878">
        <property type="entry name" value="TgpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11992">
        <property type="entry name" value="TgpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="643"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="666"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="3">
        <location>
            <begin position="532"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="789" mass="89258" checksum="B0622A66831652C5" modified="2018-01-31" version="1">MTTDNLRNIPVFGKLWEQIEAMPPPVIEDSLLLRILVQLLVIVGIVATDVASEENLNLWAVPVSIVGATWSWYRRRDRNVAAKFCIAIGMLVALFAFFSRLVGELNDTRLVLAQLLIQLQVLHSFDLPRRKDLGYSMVIGLILLGVAGTLSQTLTFGPMLLLFLAVSLPTLVLDYRSRLGLSKIEDKKQNLEGKEKQKNNNWSLFAATLSPKYLGLLLLITIGLGLTIFAFLPRLPGYQLRTFPVSAPIEYKGEFDSRSILNPGYVRGGNNKGTGGGRGRNPDKGPGEVDSTFYYGFNQRINQNLRGEMKPAVVMRVRSQAAGFWRVLGFDKYTGQGWEISRNEQAQKVTRPRWSFQFFMNPFPNAPRTEEVIQSYTIVAQLPNLIPALNKPKELYFPTTDVAVDAEGGLRSPVELAEGLTYTVISNVPFRDRDLLNKTGTDYPKNIRKFYLDVPPKIAAKVRAKTEEILQARTRVSKSERAIDSPYEKALYLAQYLKQNPNYKIEKALPYLEETEDLVEGFLFGYQNTQDGKKVTGGYPDHFSTVLTIMLRSIGIPARMAGGFDTGEFNPFTGLYIVKNTDAFLMTEVYFPNNGWFGFNPIPGYPLIPASVEDNQTFSALESFWKWIAGWLPTPLRSGLDSVFAFVFGWIGLIVGWFLGQFAKGWVGLFTGLISAIAFGFIGWLIWQLWRKWRYRRWLGKLPAVEGVYQEMLKDLASRGFAKPRAQTPLEYAEAMRANHAIDEAEVIEEVSQAYVRWKYGGEMGNLNQLRLLVGNLRRSYLRKLKKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F148</accession>
    <name>A0A2G4F148_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4189 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000051">
        <property type="protein sequence ID" value="PHX55475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55475">
        <property type="protein sequence ID" value="PHX55475"/>
        <property type="gene ID" value="CP500_010650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025240">
        <property type="entry name" value="DUF4189"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13827">
        <property type="entry name" value="DUF4189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013552150" evidence="1">
        <location>
            <begin position="29"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4189" evidence="2">
        <location>
            <begin position="32"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="13063" checksum="2E82E9CEC808FE71" modified="2018-01-31" version="1">MFQKLFSKCVIATVLTLPILLCTQTAQAQNKHGATAYSATSDTTGISWDHATEKAALDAAVAACNQQSGGANDCKPLTSNTNNCGAIVVGKGGAGAGWGDDKASAEAQALAACSELPGGSCKVQLSVCNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F155</accession>
    <name>A0A2G4F155_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Secretion protein HlyD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_010300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55489">
        <property type="protein sequence ID" value="PHX55489"/>
        <property type="gene ID" value="CP500_010300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="4">
        <location>
            <begin position="118"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="244"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="331"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="560" mass="58177" checksum="4F2A86023AB06985" modified="2018-01-31" version="1">MKPTNETNPAEFNGNGKGKAVALLEKPIDDTIAKSLPIIPAPETEISAPSDVKTGAETELQAPLPTAATPKKKSKKPMIFALLGVGAIAAGGFGYHYWQYASIHQETENATVAGHIYQISSRVNGTVGEVMVKDNQQVKPGQLLIKLDPRDYQVKVQQAQAALENARRQAEAAEANISLASQTSQGKTTQAQGDISGANAAISTAQAALREAQQGVPAAEATVAEAQAGVPAAEAKVTQAQAGIPQAEAKVTEAEAGIAQAQAQLAQAQATLVKTQADYKRYEGLQTEGAIARQQLDSAKAAYDVAVGQTTAAQQGIAQARARLAQATEGVTAAQATVAQAQEGVKQAQAQVARAQVGIASAQAKVAVAQEGITTAQAKLATSKGGLQQAEATGEQTKVSRSQYDAAKAAIAQSQASVKDAQLQLSYANITAPAAGQIGRKSVEVGQRVQSGTPLMAIVSNDLWVVANFKETQLANIKPGQKVEIKLDAFGGRKFEGRVDSFSPASGAQFSLLPPDNATGNFTKVVQRIPVKVVFDAESVKGYESRIAPGMSATVNVELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F166</accession>
    <name>A0A2G4F166_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphopantetheine-protein transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55499">
        <property type="protein sequence ID" value="PHX55499"/>
        <property type="gene ID" value="CP500_010350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="2">
        <location>
            <begin position="127"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="253" mass="29068" checksum="9688AF4089E73290" modified="2018-01-31" version="1">MVTPLDSWNSPQKNLKLASNEIHVWRVFLEQTASCLQSLQQNLSTDELNRLERYYFQKDREQFIVSRGALRAILSRYLDIKPSALNFAYNLYGKPFLDSPLAKNTLCFNLSHSHGVALIAITENRDIGIDIECIRTNLPYQQIAESCFSQLEKTVLRSLPEHLQHKAFFTCWTRKEAYVKAVGKGLYIPLSHFDVAFAPGEPAALLRFQDDPQEIFRWDLIELIPASDMVAALAVEGYCSKLQRFQWQHPSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1A3</accession>
    <name>A0A2G4F1A3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55540">
        <property type="protein sequence ID" value="PHX55540"/>
        <property type="gene ID" value="CP500_010480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="108" mass="11079" checksum="A69E40D948EC82DE" modified="2018-01-31" version="1">MSSSLIISDLNYLQTLDQSSSVVGGGSVYAGTVTTTNIGLGYAVGGAGAVTIGQTTYTNTQTNTTVKNLGMLNYSRADAAAIAYAKTGDQMALSSSFNTSIFLNFTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1D3</accession>
    <name>A0A2G4F1D3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sirohydrochlorin chelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_010275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000049">
        <property type="protein sequence ID" value="PHX55563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55563">
        <property type="protein sequence ID" value="PHX55563"/>
        <property type="gene ID" value="CP500_010275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="250" mass="27134" checksum="63343E9AF6B230CC" modified="2018-01-31" version="1">MRSTYLLVSHGSRDPRPQLALENLAQLLSQNLPILSNSVASSVPAVGTATLELGAPLHEQICRFAEHTLSLGLTEVQILPIFLLPGVHVAEDIPAQVEIAKQTLSSKLKIELQPHLGTQEAGLANLVKNQMQEVAFLHNLHSPKWILLSHGSRRPSGNSTVEEIASKVGAHAAYWSVKPSLEERIDSLVRDGQQQIGIVPYFLFNGGITDAIAKKVTELKQQFPTAEIHLANPLGATVELADLIGELIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1E1</accession>
    <name>A0A2G4F1E1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000048">
        <property type="protein sequence ID" value="PHX55572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55572">
        <property type="protein sequence ID" value="PHX55572"/>
        <property type="gene ID" value="CP500_010095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="103" mass="11788" checksum="AA7B804935571B95" modified="2018-01-31" version="1">MTIKEQLLQTIETLPDDLLAATLKFVQTLQHPIHKTPGICGGAARIRDTRIPVWTIVTYQQQGANESELLYNYPGLTLQDLEAVTNYYESNREEIELWLAENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1H7</accession>
    <name>A0A2G4F1H7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Photosystem II reaction center protein L</fullName>
            <shortName evidence="8">PSII-L</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">psbL</name>
        <name evidence="9" type="ORF">CP500_009995</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Cyanobacterial PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Ycf12, at least 3 peripheral proteins PsbO, PsbU, PsbV and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cellular thylakoid membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PsbL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000047">
        <property type="protein sequence ID" value="PHX55599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015176850.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55599">
        <property type="protein sequence ID" value="PHX55599"/>
        <property type="gene ID" value="CP500_009995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01317">
        <property type="entry name" value="PSII_PsbL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003372">
        <property type="entry name" value="PSII_PsbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037266">
        <property type="entry name" value="PSII_PsbL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02419">
        <property type="entry name" value="PsbL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161017">
        <property type="entry name" value="SSF161017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="2 8" id="KW-0674">Reaction center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="40" mass="4642" checksum="5EDB5E1435A1C7EF" modified="2018-01-31" version="1">MPERVPNPNEQPVELNRTSLYLGLLLIFVLGILFSSYFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Q4</accession>
    <name>A0A2G4F1Q4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55675">
        <property type="protein sequence ID" value="PHX55675"/>
        <property type="gene ID" value="CP500_009715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="52"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="125"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="176" mass="20402" checksum="C006C5F36797FB06" modified="2018-01-31" version="1">MDSNLLIIYLSVLLLILGSASWFIVRQIFTTRNREMSLERLENKLTTEKGTAQEYYELGSIYLDKGLYSQAILLFQKALKSEDLEGAENSAIIYNALGFAHFSQEQYDIAIRHYKEAIKLQPEYITSINNLAHSYERKKLVSQALEMYEEVLKYEPANDTAKRRVESLRKRFVSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2C7</accession>
    <name>A0A2G4F2C7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="6">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_008360</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000037">
        <property type="protein sequence ID" value="PHX55898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A2G4F2C7"/>
    <dbReference type="EnsemblBacteria" id="PHX55898">
        <property type="protein sequence ID" value="PHX55898"/>
        <property type="gene ID" value="CP500_008360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="284" mass="31175" checksum="0C1A4B868D4E8CAC" modified="2018-01-31" version="1">MPQLQRLAVNPAQICDRTINLTPEQQHYLHRVLRLNQGDKFIAMDGRGHWWLAVLEAQETGLIASITEEIAVNRELGVEVTLMAALPKGNGFDEVVRQATELGVASIVPVTSDRTLLKPSAQKVDRWKRITAEAAEQSERQFVPTILEPISFDLAVKDCGQKYRYICVARGDNRHLWDCLISLEPPQPPLVRGEQELEPPQPPLVRGEQEFDPAFVGAVPPCPPPGGELSIVIAIGPEGGWTDGEVKRAIEFGFEPVSLGSRILRAVTAPIVALSLVGAAFEKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2H6</accession>
    <name>A0A2G4F2H6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55948">
        <property type="protein sequence ID" value="PHX55948"/>
        <property type="gene ID" value="CP500_008225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="156" mass="16883" checksum="7D4207D37CC20138" modified="2018-01-31" version="1">MGAKIEFLVGGHPAWGGHPARPLATGKMPVPQRFNFLVGWASCPLATGKMPVPQRFNFLVGWASCPLATGKMPVPQRFNFLVGWASCPLATGKMPVPQRFNFLVGWASCPLATGKMPVPQRFNFLVGWASCPSATGKMPVPQRFNFLVGWASCPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2I1</accession>
    <name>A0A2G4F2I1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tat pathway signal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_008245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55952">
        <property type="protein sequence ID" value="PHX55952"/>
        <property type="gene ID" value="CP500_008245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013901987" evidence="2">
        <location>
            <begin position="29"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="3">
        <location>
            <begin position="65"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="372" mass="40017" checksum="4DF0A7F662E751BE" modified="2018-01-31" version="1">MNNTWLRRSLSLVLIATPVILSSCQSQPNATTTPASGGATATTAADTSQKRTIKVNPSWLLQGDNAPLTMAIDKGYFPAEGLDVKIERGYGSSDTITKVAAGQFEIGFGDIYSMMEFNAKNPNDPVVAVAVPYNRSAFSIVTLKSSNIADPKALAGKKLGAPAGDAPRKLWPVFAQKVGVGADSVEWITMEPKLRETLLIKGDVDAVSGFATTIIPALEKSGKKPEDMNVFYYTDNGLDLYGNAIVVKKAFLDKNPEVVKGFLRAYFKGLQDTLKDPTAGLESVVKAGDSLMDKNAEKRRLQIALERLYITPEVEKVGLGGVDPVRLEATAKQVAEVLKIPAPPVDKIVDESYLPPKEQRALPPAGDRKPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2W0</accession>
    <name>A0A2G4F2W0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56113">
        <property type="protein sequence ID" value="PHX56113"/>
        <property type="gene ID" value="CP500_007350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025751">
        <property type="entry name" value="RsbRD_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14361">
        <property type="entry name" value="RsbRD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="170"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="401" mass="44709" checksum="B6F09ABADA4BF79D" modified="2018-01-31" version="1">MDYSQLLTDKTDTILTNWIQAVRLDRKIESADTLPHSAIINHIPHLLSAMATVLSYYQDSEIKIIIKASLDHGFLRAEQGYDAAEVAREYHLLRQVIFSNIEAELLTGTTTEVVRTFRLIDAVVDEAIAQCFNSYVAQRLSELQQIQTQLTLTNQELNRLVNANQENLSYLAHELKTPLNSIIGYSELFLRQEKKQPEIKDTLPGIEHIERVLRNGRQLLRLVNDALELSRADAGKIQLRLRPTNVQSIISTVVEVMQPMADAKGLKLVITTDCAPKQVIGDSQRLQQIITNLLSNAIRYTATGSIELHCRQVGSEKWAIAITDTGIGIAPEDKNRIFDPFFQAGEAGKQQFSSESTGLGLAIVSRLVKLLQGKIELVSETGVGSTFTVVLPLEVKTLQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F322</accession>
    <name>A0A2G4F322_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine(34) hydroxylase</fullName>
            <ecNumber evidence="1">1.14.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA hydroxylation protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trhO</name>
        <name evidence="4" type="ORF">CP500_006870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + O2 + uridine(34) in tRNA = 5-hydroxyuridine(34) in tRNA + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:64224"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrhO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56161">
        <property type="protein sequence ID" value="PHX56161"/>
        <property type="gene ID" value="CP500_006870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00469">
        <property type="entry name" value="TrhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="PTHR43268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="123"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="315" mass="35508" checksum="0806CF0DB08AADAA" modified="2018-01-31" version="1">MADFLTAALYKFVELSDFANLRAPLLACCEANQVVGTILLASEGINGTIAGAPESIYAVLAFLRSDPRFADLVHKESYSEKLPFYRLKVRLKREIVTMGVPDINPNQMAGQYVKPEEWNKLLDDPDVVVVDVRNDYEVSIGTFKGAINPQTKSFSELPEWVEQETALQHKPKVAMFCTGGIRCEKSTAFLRKIGFDEVYHLEGGILKYLEIVPEAESRWEGECFVFDERVTVGQGLKPGDYELCRACRHPISPEDRTSELFVMGVSCPHCYGTKTEAQKQSLSERQRQIELAKSRHQKHIGARYHAQEKPDDSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3F7</accession>
    <name>A0A2G4F3F7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56265">
        <property type="protein sequence ID" value="PHX56265"/>
        <property type="gene ID" value="CP500_006260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="87" mass="9759" checksum="51AD4D6B8AF839C8" modified="2018-01-31" version="1">MGITYTTLKIRNFLTDSEIVDLEAKVDTGATMLVLPESTAAQFNFPKIRKQIVKYANEETAERDIIVGGLQIYPNPRSPNMPMAEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3H4</accession>
    <name>A0A2G4F3H4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56309">
        <property type="protein sequence ID" value="PHX56309"/>
        <property type="gene ID" value="CP500_006145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="31"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="213" mass="25052" checksum="C93D84334831E0EF" modified="2018-01-31" version="1">MLTSDLNALLDQQALQRQDPECRYITDRVNWEQYETLLTRNGDTSAYRVTYLDGALEIISPSRRHEIRKTRIGDLLVIYFLEADIDYFPFGSTTLRREENSGGTEPDEAYCIGTDKEFPDLAIEVVVTSGDLNKLEVYRRLNVKEVWFWQNERFSLYYLQEEIPVQFVQICGYEQIDRSEILPNLDIELLAEYVRYPNSLAAVKEFRQRLISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3L3</accession>
    <name>A0A2G4F3L3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsU</name>
        <name evidence="4" type="synonym">rps21</name>
        <name evidence="7" type="ORF">CP500_006005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006632476.1">
        <property type="nucleotide sequence ID" value="NZ_NXIB02000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56336">
        <property type="protein sequence ID" value="PHX56336"/>
        <property type="gene ID" value="CP500_006005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018278">
        <property type="entry name" value="Ribosomal_S21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="PTHR21109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01181">
        <property type="entry name" value="RIBOSOMAL_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="64" mass="7712" checksum="BEE3088D6901593B" modified="2018-01-31" version="1">MTQVVIGENEGIESALRRFKRQVSKAGIFPDMRKHRHFETPLEKQKRKAIARRTKRRFHRNNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3R9</accession>
    <name>A0A2G4F3R9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56423">
        <property type="protein sequence ID" value="PHX56423"/>
        <property type="gene ID" value="CP500_005295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="12"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="184" mass="20626" checksum="3EF0B4F12B298E8E" modified="2018-01-31" version="1">MTDGNRKKALFILSQLNNDDINWIVQKGKKEIIDSGRVLIHEGRQIDALYIVLKGNLSVLLEAEGTKELAKISSGELVGEVSFIDARPPLATVKAIEKTELLAIPRRQLILKLQNDMGFASRFYCGISLCLADRMRGTIRHIEYGRNLELENSELDQGDINPSVMENLALAQAKFNWLMENVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3X0</accession>
    <name>A0A2G4F3X0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="4 12">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_005285</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the ALAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="4 12"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56421">
        <property type="protein sequence ID" value="PHX56421"/>
        <property type="gene ID" value="CP500_005285"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="PTHR11458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX56421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="327" mass="35861" checksum="75B6DEDBB8D33A71" modified="2018-01-31" version="1">MFPTHRPRRLRNHPQLRRMVRENILTTSDLIYPLFAVPGENFAKEVISMPGVYNLSIDKIVEEAKEVYDLGIPAIILFGIPADKDIDATGAWHDCGIVQKATAAVKQAVPDLIVMVDTCLCEYTSHGHCGYLQVGDLSGRVLNDPTLELLKKTAVAQAKAGADIIAPSGMMDGFVGAIREGLDDAGFEDIPIMSYAAKYASAYYGPFRDAADSTPQFGDRRTYQMDPGNGREALKEIALDIAEGADMLMVKPALAYMDIIWRVKEATNLPVAAYNVSGEYAMVKAAALNGWIDEERVVMETLTGFKRAGADLILTYHAKDAARWLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F416</accession>
    <name>A0A2G4F416_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56502">
        <property type="protein sequence ID" value="PHX56502"/>
        <property type="gene ID" value="CP500_004925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="13113" checksum="4FDE1FDFD33A72E0" modified="2018-01-31" version="1">MDRLDYYRQCIEKLLLESGEDPPINGQIEVEFVFDKERDRYLVIDLGWNEHDRIYNCFIHLDIKDGKIWIQRNQTDRSFADELVQMGIAKEEIVLGVQPPYAREYTGFGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F421</accession>
    <name>A0A2G4F421_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56533">
        <property type="protein sequence ID" value="PHX56533"/>
        <property type="gene ID" value="CP500_004600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="35"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="296" mass="32604" checksum="0ECA8E4B86E2D6DE" modified="2018-01-31" version="1">MTTQQLVSANSLEKLIWTWRDRKIQYTVQGTGRPLILIHGFGASIGHWRQNIPALAAGGYRVFALDLLGFGGSAKPALDYTLELWEELLTDFWTELVQEPAVFVGNSIGALLSLMVVANHPEISAGAVLINCAGGLNHRPEELKFPLGLVMGTFAKLVRSPIVGPFLFNNIRQKHRIRNTLRQVYGNREAITDELVELLHAPSCDPGAQQVFASILTAPAGPQPSELLPKVDRPLLVLWGADDPWTPIAGSKIYQDLVDDGRSVKFVSIPKTGHCPHDERPTEVNTLILDWLAQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F443</accession>
    <name>A0A2G4F443_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56554">
        <property type="protein sequence ID" value="PHX56554"/>
        <property type="gene ID" value="CP500_004715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013841484" evidence="1">
        <location>
            <begin position="22"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="21861" checksum="EE7EB59963970BB5" modified="2018-01-31" version="1">MKYKTLSFLVVALFTVTAGMAAQVNAASQDVQKQNVRSVQAQASGSQAIPVALPTIAKISMKKGEPTSGRVVEIDEKTQKISLQRGRDKVSIPLSQIEKIVFPKTAEVYLSNGEMPKVRGDGTPAKGRPETWRGIPMNAFRLLDPNKGQADVKLGSVLSLDKLDSLNSVIVGDGKNKRQFVVDEMQFDVQKKTMTIAATPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4F7</accession>
    <name>A0A2G4F4F7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56625">
        <property type="protein sequence ID" value="PHX56625"/>
        <property type="gene ID" value="CP500_004225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="28"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="27936" checksum="F4FD35042EA75A5F" modified="2018-01-31" version="1">MVFTALELAAIMPDASKIESDEPEMESSLHYLQLSLLVACLEWLWRDRNNFFIGANLTVYYSEQQLRNRDFRGPDFFLVRNTEKRPRRSWVVWQEDGKYPDVIIELLSESTAKVDRNAKKILYQNRFRTPEYFWFDPEDFELAGFRLIGQEYQAIVANESGRLWSDILELYLGIHEGKLRYFSPDGELVPTPEEAALQAQEQAQQAQEQAQQAQEQAQQAQQRVERLADQLRALGIEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4F9</accession>
    <name>A0A2G4F4F9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56674">
        <property type="protein sequence ID" value="PHX56674"/>
        <property type="gene ID" value="CP500_004050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="13111" checksum="8568EC752435F900" modified="2018-01-31" version="1">MEKLIKYRQIVQQMLQEYGKHKPAHGDIEVETIFDTKRDYYQVFLVGWDDHKRVHHCSIHIDIKGGKIWLQWNATEDDIAENLVIAGVPKEDIVWGFQPPLMRKYTGYAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4J1</accession>
    <name>A0A2G4F4J1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56655">
        <property type="protein sequence ID" value="PHX56655"/>
        <property type="gene ID" value="CP500_004415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="109" mass="12437" checksum="D20C317F7AD660ED" modified="2018-01-31" version="1">MNKVSKRPQVIQDLIGLATYIAEDNLDASDLFLQAAEETFKQLGKIPQMGKLSQFSNPNLAGIRQQAIKGFRKYLIFYRSTDEGIEILRVIHGVRDLEAILDRDLEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4L4</accession>
    <name>A0A2G4F4L4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidoglycan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_004020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56702">
        <property type="protein sequence ID" value="PHX56702"/>
        <property type="gene ID" value="CP500_004020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013733998" evidence="2">
        <location>
            <begin position="26"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="3">
        <location>
            <begin position="86"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="3">
        <location>
            <begin position="178"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="236" mass="24667" checksum="74CFEEBC9F5E173F" modified="2018-01-31" version="1">MRITTATILGLVALVTPGLTRNATAAFESKSFVQEQSSQDLVTPADSGASASPEANSDRKMFNKPFYAGEQKPVRKEKTISAGADGPEVAAIQQRLQIHGFAIGKIDGSYGSRTTSAVNDFQQSKGLNSDGIVDKSTWTALAADPVPASKVSQNNAPIENEAAVPSKTVTILTKGSFGAKVKTLQARLEVAGYAPGPIDGIFGARTISAVKGFQESQGLKANGVVDEITWKAIGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4R8</accession>
    <name>A0A2G4F4R8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56739">
        <property type="protein sequence ID" value="PHX56739"/>
        <property type="gene ID" value="CP500_003775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="240" mass="27420" checksum="4816E28B638CFCBE" modified="2018-01-31" version="1">MPPRSQNLSFTAEFIEEICLEIFAATCTKKIDKKSGKEVKTYKKVKNAKVEIISVSLVKSEKGQQLLFDYQSAEGIRRTVSTFNFMSDFTLAWDVTPEWSALKYRIHKPLNSNFSPIESRALYDLFGKWLISDAFVQHITVFSDQGVYAPELIKLLLLYFAYQQGRYSKAEELGGYSLTMEIDLDRVVVIFKEYIKEYISGFSEDFVHLKKHYNVSQFTLSAAATPAIESIQVTPSTPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4W6</accession>
    <name>A0A2G4F4W6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56537">
        <property type="protein sequence ID" value="PHX56537"/>
        <property type="gene ID" value="CP500_004620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="5"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="123" mass="13825" checksum="C274D16362794814" modified="2018-01-31" version="1">MSQIRLYLDEDTLRKAFVQALRENGVDVVTVSDANNLGRIDEEQLIWATEQGRVIYTFNSRDFCRLHGSFLAVGGSHAGIIVAPRQSYSVGEQLRGLLNLIGSKSAEEMMNQLEFLGTYIRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4X5</accession>
    <name>A0A2G4F4X5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(2Fe-2S)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56775">
        <property type="protein sequence ID" value="PHX56775"/>
        <property type="gene ID" value="CP500_003975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="PTHR23426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="17599" checksum="3A4207FECB46D6AA" modified="2018-01-31" version="1">MVKIIRLDPIAEEMAVETRSNILSALLSKDLDVLKECGGRGMCATCHVYIKEGMEGLSGMNRRERRTLEVITTAASNSRLACQAEIMGEGVVVQIPAGMYINAIENVEALIGRRAQQDLLHPITGQVVVESGKLITRSIVTQLNETRFQVGQYLVRTKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F530</accession>
    <name>A0A2G4F530_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56860">
        <property type="protein sequence ID" value="PHX56860"/>
        <property type="gene ID" value="CP500_003020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="43"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="218" mass="24606" checksum="196BCDC13DCA4702" modified="2018-01-31" version="1">MNLQLELSKFKREFLLKIPSEKAVIMQGATQALAKEFQNRRALRIDDEAPDFVIQNTDGQQISLYDKLNQVAVILTFYFGGWCPYCNLELRAYERLLPKIQALGASVLAISPQTLDASQKTVLNNGLSFDVLSDAGCQIARDYGIVFEIPDRLRLLYTELGHALPDYNGTEDWLLPVTATFIIDRRRHIALAHIDVDYTKRYEPADAIAILLSLFVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F554</accession>
    <name>A0A2G4F554_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56933">
        <property type="protein sequence ID" value="PHX56933"/>
        <property type="gene ID" value="CP500_002850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="194" mass="22600" checksum="A63BC7D002DC5BD0" modified="2018-01-31" version="1">MPKIVDHEHYRKQLLNQCFELFAEKGYSSVTMREIASEIGVSTGTLYHYFPSKESLFEQLIEYLSYEDTKEEALVELGNPPTLAERIEKMMDYVSKNEDYILKNCLIIFDFCHHKNRQEIDRNQALQEAGKRYEEAVSCYLGISDPAISIFVINYIDGLLGRRFHQGERISFTEQAKLLKEILLAYLGQNHNCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F593</accession>
    <name>A0A2G4F593_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_002895</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56942">
        <property type="protein sequence ID" value="PHX56942"/>
        <property type="gene ID" value="CP500_002895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="251"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="326"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="292"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="572" mass="63433" checksum="92609985B4F4419C" modified="2018-01-31" version="1">MFSTLASKNQPHNPPQTGLKILFSRLGIRQKIGCGYALVIGIAILGAATGRGVESYYKQQVREQLAIDRDKAEILTNLNNTAQEVRIQQLLLLSMTTKPQIFDRERSDFLTHVAQMSAQLEQLQNLPPTSNPAVAQDYQQIQEFAKANSKIVEAYFQQVQKLLGNAKLSGLNPKQRQDFERNLNNFVTSNNAFKLEKFSQDCAQLAGSFREKADEAFRNYEKAEQLGTLILIGSLFISAAIAVMLAVYTSRAIARPLKATTLIAQRVTEESNFDLQAPVTTSDEVGLLAISINELIQRVAEYTEDLQEAKIAAEAANRSKSAFLANMSHELRTPLNAIINYSEMLQEDAQDSGSEDFLPDLQKIKTAGKHLLDMISDILDISKIEAGHVTLYLENFDVATMVEEVMTTAQPLVEKKGNSLALKTEGELGMMYADQPKVRQILLNLLSNAAKFTEKGVITIGIERMKNEKSRPMRKHKNNDDSSPGSQYTAQVLVFRVSDTGIGMTEEQLQQIFKPFTQADVSTTRKYGGTGLGLTISQRLCQILGGEIRVESQDGKGSTFIVSLPERVIMQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5B3</accession>
    <name>A0A2G4F5B3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpG</name>
        <name evidence="9" type="synonym">atpC</name>
        <name evidence="10" type="ORF">CP500_002490</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56974">
        <property type="protein sequence ID" value="PHX56974"/>
        <property type="gene ID" value="CP500_002490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="316" mass="35015" checksum="E269CC6BE9858E32" modified="2018-01-31" version="1">MANLKTIRDRIKSVKNTKKITEAMRLVAAAKVRRAQEQVTATRPFADRLAEVLYGLAERLQFENLDLPLLKKREVKTVGLLVVSGDRGLCGGYNSNIIRYGENRAKELKAEGVEFKYILVGRKATQYFQRREQPIDATYTNLEQIPTAPEAAMIADELLSLFLSGTVDRIELVYTKFVSLISSRPVIQTLLPLDPQGLETPDDEIFRLTSQGGEFKVSRDKVAAPTKSLPRDMIFEQDPAQILDALLPLYLNNQLLRALQESAASELAARMTAMNNASENASDLIGSLTLTYNKARQAAITQEILEVCGGAEALNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5F7</accession>
    <name>A0A2G4F5F7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56941">
        <property type="protein sequence ID" value="PHX56941"/>
        <property type="gene ID" value="CP500_002890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="SSF50199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013552152" evidence="1">
        <location>
            <begin position="33"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="2">
        <location>
            <begin position="32"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="190" mass="21128" checksum="C6DD8C78B5162B4F" modified="2018-01-31" version="1">MSQIKIAIFPTIKRLSAVIMLLLLFGCPQKFAANNYAVKRVSDGDTLVASDAAGKDIKVRFACVDAPEIPHTNAEKNSKASAQKNQFKWGMLALQRTQQLVKQGGDRVVLAVTDTDRYGRQVSEVRLPNGTFVQEVLTREGLAMVYRPYLKKCPSASILEQAEAEAKKSRSGVWGDSKFVPAWEFRHNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5H6</accession>
    <name>A0A2G4F5H6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57053">
        <property type="protein sequence ID" value="PHX57053"/>
        <property type="gene ID" value="CP500_002355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="174"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="525"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="831" mass="94169" checksum="C62B062354D81FA4" modified="2018-01-31" version="1">MALLEGVEQGWSRGEIKGFLIGTKINDAEWVNWLQDFGERLLVSPETHLELGGRMVRLGEMNCGRISEVAGNIGRQLLAGERLNPTPTDDSSISDNVPELLGRESLSFPTGDLSVVNLKNVTKTEAYKILIEIANNRVEAIELYNQGNERYYAGDLEGAIAAYEKALEIDPKFHLAWNGLGGTLNDLGRYSEAIAAFEEALKIDPTFHLAWNGKGIALNHLGCNTEAIAAFDTALEITGDQYWMAWENRGWAFFNSGRYTKAIHNWDQGLRKYQPSKHDYHLACGKLHQQKGDAHYKHGEQTATYCEFSPKAKDSYEQARKFLKSPRRRIRETYLEVMVGLITVCRSLGDPKTSEYLTEATTVLENLLLDNQTHPKIKLRFHRKFAGLYQLEVDTLVESGKKINALEKAELRKNFCLQWMRAGWQNRTDSPTYPQTRDLLANNTETAIIYWHLSPVSLTAFIITLEKFEVITTPVTDLSAKRESQSLEKWVKNWKTSYQNYGKTTSKRQSKESHPWRESMTAQLPQLADILKIPEICTHLTNIQNLILIPHRDLHLLPLHILFSDHLFTITYLPSIQVGIDRLDRQPSSSMSLLLVESPDPLLFAEIEAPAIVNFYLNCCNTIPSSQATTDNVKEALQQAADIFHFTGHAYHNTKQPSQSALILKNKQLITSEEIAKLELKSYYLVCLSACETGITGKEELIDEFVGLASSFLAAGAVYALSTLWIVDEISTALMMIRFYEILNEQRCQNKLHPALALKEAQKWLKTITYSQLSDWYLGLAKITYNSSCSQYLRDEANLIRRNDAKMVSQEPPYADLYHWAGFTITGKVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5M8</accession>
    <name>A0A2G4F5M8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_002135</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57011">
        <property type="protein sequence ID" value="PHX57011"/>
        <property type="gene ID" value="CP500_002135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="PTHR31632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="314" mass="33961" checksum="4F1A3D30D188E6B5" modified="2018-01-31" version="1">MNFGEALPTFVITLREGVEAALVVGIVLACLKKSGQSYLSPWVFGGVGVGLLASAFIGVLFGWTIQILSTSNQPFAPIMEALLEATFGLVAIAMLSWMLIWMTKQARFMKAEVEGAVSAALTQNSHAGWGVFSLVLIAVLREGFETVLFVVAKFQEGIIPAIGALGGILSAAGLGVLLFKWGVKINIRLFFKYMGILLLFIVAGLVVSTLGLFDTVVNTLSQANRESAGLCFYYERFAKVHSCILGPMVWNTSQVLPAEKFPGLLLSALFGYTDKLYVVQAFSYLVFLGTVGGMYFQSLAGRVFFPFKKTEATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5N7</accession>
    <name>A0A2G4F5N7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57066">
        <property type="protein sequence ID" value="PHX57066"/>
        <property type="gene ID" value="CP500_001955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7235" checksum="3D5424A57EB22584" modified="2018-01-31" version="1">MFCLTPEARNLELVKTGNRGFRGSRASAASRMQVRSSRVYKDEALVAATLRGLTELLSSLESFRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Q1</accession>
    <name>A0A2G4F5Q1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_003525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56807">
        <property type="protein sequence ID" value="PHX56807"/>
        <property type="gene ID" value="CP500_003525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045434">
        <property type="entry name" value="EAD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19959">
        <property type="entry name" value="EAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="3">
        <location>
            <begin position="274"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1345" mass="151577" checksum="3F012D489B0B3E4A" modified="2018-01-31" version="1">MIFTQNIAMARKYGKNATTKNNVLKLVEALLALADGEIAVPGDKLKATFNVEWVKEDELLVSGKVQEKRKNRTQTVEKGITKEDLWTLVECLGEALELSQPKDEEKVDNAQRKANAIQDILDCLKDLDILDPKPSAKTQGFWKFSLKLKHQTARKEDNLKVIDEQWKIKIGSVTVETTRETTFISKDQPLNWQEICRQNLAEQKKFTTKEFQRHGAELQLDEIYVPLAIVERKPPKPPSKNQQEEKEEEKLIPITEERFFEDVLRQGKSESQGRKIAIIGEPGSGKTTRLQKIADWILEQDLGLPIWISLADLTQPTITQYIEEIWLKQTGKSLNIDELTQQKERIWLLLDGLDEMTSKVETRHVSALLGGWVQAARVVVTCRVNVWEADKNAFSGFDVFRNLEFNPEQVTDYIRRWFAGMGDAATGESLEAALAQSQNSRLKELIQNPLRLWMLCQIWQTGGGLPETQAGLYGQFVDWVYDWKEDEEILDQREAIDKALARLALAAMEQKDEVSRLRLPESWVVKVLGSRPIFQAVMRLGWLNRVERFPEAICVFYHASFQEYFAALAVDDWDYFLPRNHVNFPVDGKEYRIFESQWKQVILLWLGRDIASHKKEEFIRSLVEFEYGVRDFYGDQAYFLAAAGINEFKACFLALDIVRQVVKFGFGYFNIEKQKWQNFIDPNKEGAKKAIPETIRPLAITELTAILKHCPDEDTRRWAAESLGEIGKDNLVAITALVELIRTTQNKYTQREAASSLVQIGKDNPVAITGLVELIGTTQDEDILRWAAYSLGEIDKYNPVAITALVELIATTQDEDTRREVAESLGKIDKDNPVAINALVELVCTTQHENIRSDAVYSVERIGKDNPVVITALVELIGTTQDEDILQWAAYSLVKIDKDNPVAITALVELIRTTQNKHTQVSAAYSLGQIGKDNPVAITALVELIGTTQDEDILRWAADSLGQIDKDNPVAITALVELIGTTQDEATQGRAAYSLGQIGKDNPVAITALVELIGTTQDEFTWDMAVSSLVQIGKDNPVAITGLVELIGTTQDENTRRHAASSLGQIAKDNPVAIAALVELIATTQNKYTRRDAAYSLGKIGKDDPVAIAALVELIGTTQDEDIRGQAADSLGQILTKPQQMLGVVSALKDCLSDEVYDNNFRRFYKCYKVVWGCAANLPYPQFHQAWHGLTETQTSPLVQILNLAQLPQLLKTQLTETNLHQTLQLLCIDGSKFDNRDNPATDIYLQLVKKHHCPKSTEGTPRTLTELKIYSLLLDWEKHPILIFYEDAIPQGFSPTFLDSLTRFDATICVITDSPHPTIPTFSPQEPHLIQSIITWLQRTVLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5X2</accession>
    <name>A0A2G4F5X2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsQ</name>
        <name evidence="3" type="synonym">rps17</name>
        <name evidence="6" type="ORF">CP500_001770</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57148">
        <property type="protein sequence ID" value="PHX57148"/>
        <property type="gene ID" value="CP500_001770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_S17_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9387" checksum="0FB7C815522E4354" modified="2018-01-31" version="1">MAVKERVGVVVSDKMDKTVVVAIENRSSHTKYGKIVVRTKRYKVHDEENKCKPGDRVRITETRPLSKTKRWTVAEIFGTKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Z5</accession>
    <name>A0A2G4F5Z5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">secF</name>
        <name evidence="10" type="ORF">CP500_001465</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57213">
        <property type="protein sequence ID" value="PHX57213"/>
        <property type="gene ID" value="CP500_001465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX57213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="322" mass="35245" checksum="2ED5C2E47BE18BEA" modified="2018-01-31" version="1">MQFSVIKQRSIWWSISAAIILAGIVSMAISWTRPDIRAPLRPSLDFIGGTRLQFELDCTKPENCKPIDLAAVREVLDTQGLAGSSIQVIGKEQRGISLRTKTLDVEKRTKLQTGLSEKIGAFSPQSTQIDTVGPTLGKQLFTSGLLALLLSFAGITTYLTFRFQLDYAFFAFVALFHDVLITVGVFSFLGLVQGVEVDSLFVVALLTIIGFSVNDTVVIYDRVREVIKLNPGQSIDQVVDDAVMQTLGRSINTTMTTLLTLFSIFLFGGETLKYFALALIVGFIAGAYSSIFIASTLLAWWRSRTGNSIPVPVEAINLSDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F631</accession>
    <name>A0A2G4F631_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57216">
        <property type="protein sequence ID" value="PHX57216"/>
        <property type="gene ID" value="CP500_001480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="92" mass="10215" checksum="A7EC26EF8E0EE94E" modified="2018-01-31" version="1">MMIIYFLTINPPCFLRGVRGDLGLIVKQQSLTTFDVKLTPMGTAVSSVTIAVLEKVRYALCPMPYALCPMPYARSVPHLSEKGYIISEYNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F647</accession>
    <name>A0A2G4F647_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_001340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57195">
        <property type="protein sequence ID" value="PHX57195"/>
        <property type="gene ID" value="CP500_001340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="204" mass="23586" checksum="4C29798A633CBF96" modified="2018-01-31" version="1">MVIASTKPPTLTDPTKARFTLDEYRAIEETAEERHEYCNGEIIAMSGGSPAHSRITVDVTTFLNVALRDTNFQTYNGDLRIWIPGFNHGTYPDITVIDGEPEFNADRTDEILNPLLIVEVLSPSTEAYDRTEKFRKYRSIPSFCEYLLVSQTEPYIEQYYNCDRPNSDRWQWQVYDGLDRAIVLHSLNIELPMSEVYRRINFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6C6</accession>
    <name>A0A2G4F6C6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Photosystem I reaction center subunit XII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_000760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cellular thylakoid membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the phycobilisome linker protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57343">
        <property type="protein sequence ID" value="PHX57343"/>
        <property type="gene ID" value="CP500_000760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008213">
        <property type="entry name" value="CpcD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001297">
        <property type="entry name" value="PBS_linker_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038255">
        <property type="entry name" value="PBS_linker_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016470">
        <property type="entry name" value="Phycobilisome"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01383">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00427">
        <property type="entry name" value="PBS_linker_poly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005898">
        <property type="entry name" value="Phycobilisome_CpeC/CpcI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01094">
        <property type="entry name" value="CpcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51441">
        <property type="entry name" value="CPCD_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51445">
        <property type="entry name" value="PBS_LINKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <feature type="domain" description="PBS-linker" evidence="8">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="CpcD-like" evidence="7">
        <location>
            <begin position="198"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="249" mass="28103" checksum="383D253BCD3822B7" modified="2018-01-31" version="1">MKDSTYELWPTSGVDEVQAVIRAVYKQVLGNPHVMESERLVSAESQLSDRSISVREFVRLVAKSDFYSTRYFQKCAPYRFVELNFLHILGRAPQDQTEISEHIIRCVEQGYAAEIDSYIDSDEYQTAFGENIAPYYRGRSSEANTKQVGYNRMFALDRGFAQIDSAVKASQLVYAVATNSANTIKPATSRGGAYVATEKMFKIVVTGSKFDRPRRRSTTTYIVQGNHMSSQIQRINRTSGKIASITEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6G1</accession>
    <name>A0A2G4F6G1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57329">
        <property type="protein sequence ID" value="PHX57329"/>
        <property type="gene ID" value="CP500_000685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="115" mass="13198" checksum="F3D494C80D2DB2F9" modified="2018-01-31" version="1">MTTITIEVPDELSEQLALLGEQLPELLRLCVEQPVLPSRTYRYILNFLASAPTAEEIAAFRPTPEMQERLRILVTRSKAGELTNAEQLELDEYDRIEHLVIMLKMGNLPYLTRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6H3</accession>
    <name>A0A2G4F6H3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57372">
        <property type="protein sequence ID" value="PHX57372"/>
        <property type="gene ID" value="CP500_000050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="120" mass="13370" checksum="9C301E0C76355717" modified="2018-01-31" version="1">MTTSFAVEISVSGIGVLVLFQQFDLLRCNVAEVCGWRILKFFSEFRSLSFGKSHSLKLLSLLFYLEDTSASTPPLSNLTQIFPDWWADRTGVSVVALPIITGRATKRVCMEYAEILSALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6M0</accession>
    <name>A0A2G4F6M0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AcrB/AcrD/AcrF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57365">
        <property type="protein sequence ID" value="PHX57365"/>
        <property type="gene ID" value="CP500_000015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="472"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="530"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="861"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="887"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="959"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="990"/>
            <end position="1016"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1045" mass="112854" checksum="65543C8DC038113B" modified="2018-01-31" version="1">MLNVIPKWSIAQRWLVVFGAIALTILSIHTVSRMPLDVLPNFAPPQVEVQTEAPGLAPEAVESLVTLPLESAVNGTPGVEVVRTSSAVGISVLRVVFKWGTDPYQARQLVAERLQDAQDRLPEGIGTPQISPLAPPIGTVIQYAFTSDTTSIMDVRRLVDGKINNRLLAVPGVSQVLVYGGDVQQFQVIANPEKLKALKVSLQEVVKAANEANAKTAGGLLIDPDRELVIRGEGQIKTITDLQKAVVKVQEGKTILLRDVAEVKIGAALARGDASWNTKRAVVVMVNKQPLVDSPTVTQAILKAMEEIQPGLPQDVKANVTFRQDAYIDASVGNVRSALIEGSLIVAAILIPFLMNWRTLSVCLFDFFLTLLFSLLVCSWIGLELNTMTLGGLVVAIGTAVDDAIVYCENTYRRLRENRLSPNPKPAMDVIFEGSGEVRESLIGATLIGIIVFSPIFTLSGVEGRIFTPMGIAYLVVVVISSLESLVVSPALCAILLPHKQMQTTEPFLALLSKRLYHPLLQMAMRRSTLILGLATASMVAAMLIVPTLGRDFLPTFQERSLMNAIALYPGSSLEATNRVGLAIQTALKDDPRFESVQLRSGRAPGDPDAASVNLAHLDVELSEAAMKNRPATIQALREVLGQFPGVAGNVGGFISHRMDEVLSGVRSAIAIKVFGNDLQELRRIGEQVETTMKDVKGLVDLQLEPQIPIRQVQIQFNRDAAARYGLTIAQLSDFTETALNGRVVGQVADGQQLVDVLVWVNESARRNLNTIRNLQVNTPTGKIIPLSEVAKVDFGNGPNTINRENVSRLIVISANIQGRDVSSVVDDIRAKVKRSVQLPQGYYIQYGGQYESEQRAAQNFLIFGILAVVAIAVLMYFTVKSVPAMLMVMVNLPLALVGGVISVLLTGGVLSVPSMVGFVTLFGVATRNGLLLVDNYNTKLAEGMPLSEVIVEGSMERLLAILMTALTSALGMIPLVLSGGAGKELLQPLAIVVLGGLFTSTALTLLVLPALYARFGKFLMPKRMMETTELKNYGIEQTSTKEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6P3</accession>
    <name>A0A2G4F6P3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57442">
        <property type="protein sequence ID" value="PHX57442"/>
        <property type="gene ID" value="CP500_000460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8580" checksum="273D3EA3D3D75DA7" modified="2018-01-31" version="1">MSPVMLRQLWSLIETTQATLLVTLDDATLVQWLLKQLKMNSALNGKEADLLDEYIQSRLSLIRDLAEQRLAPELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6T7</accession>
    <name>A0A2G4F6T7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmB</name>
        <name evidence="4" type="synonym">rpl28</name>
        <name evidence="5" type="ORF">CP500_000935</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57237">
        <property type="protein sequence ID" value="PHX57237"/>
        <property type="gene ID" value="CP500_000935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="PTHR13528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="9244" checksum="DFD1252564886C86" modified="2018-01-31" version="1">MSRKCQLTGKKANNGFAVSHSHHRTHKLQEANLQWKRVWWPQEKRWVRLHLSTKAIKTLQHKGLEIMAKEAGINLYKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUK8</accession>
    <name>A0A2G4EUK8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate 5-kinase</fullName>
            <ecNumber evidence="8">2.7.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Gamma-glutamyl kinase</fullName>
            <shortName evidence="8">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">proB</name>
        <name evidence="10" type="ORF">CP500_022610</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + L-glutamate = ADP + L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000235">
        <property type="protein sequence ID" value="PHX53232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53232">
        <property type="protein sequence ID" value="PHX53232"/>
        <property type="gene ID" value="CP500_022610"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="274"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="164"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="208"/>
            <end position="214"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="365" mass="39116" checksum="BF37D09A5E6404AD" modified="2018-01-31" version="1">MVVKIGTSTLTRSTTGNLALSTIATLVEVLVNLRQQGHQVVLVSSGAVGVGCARLGLTERPRNIALKQAVAAVGQGRLMRVYDDLFTTLQQPIAQVLLTRRDLVHRNSYVNASNTFGQLLRLGVIPIVNENDTVAVDELKFGDNDTLSALVASLVEADWLFVLTDVDRLYSADPRSNPDAQPIALVQSMAQLTEFQVQTGDSRSGWGTGGMVTKIEAARIATASGVRTVITDGCFPANIEKIINGESIGTQFEPQPRPVNARKHWIANVLIPAGKLYLDAGAVNAIAQGGKSLLAAGISQIEGEFKAEDAVRLCDTEGKEIARGLVNYHSLELRQIQGSKSDKIAEILGYAGVETVVHRDNLVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUK9</accession>
    <name>A0A2G4EUK9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_022675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000240">
        <property type="protein sequence ID" value="PHX53214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53214">
        <property type="protein sequence ID" value="PHX53214"/>
        <property type="gene ID" value="CP500_022675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="336" mass="33655" checksum="DC11B732BB6998A0" modified="2018-01-31" version="1">MSQVTTGTVTNPTEPQSVQPNDTGGLIIQGSPDLQNRLSGSIGSDQIDLGDRGDQAFGGDGSDTIIGGQGADSVGGGTGDDFVEGGAGDDLVSGNSGKDTVIGGEGSDTVIGGKSDDVVDGGAGEDVLFADEGNDFVQGGAGNDLLFGGEGNDSLDGGDDNDALFGGKGSDLVESGASDDLVNGNLGNDSVTGGEGNDTLFGGKGNDLVEGGTGNDIIYGNSGNDTLTGGAGADIFRFEFVGPDNVDTLTDFNPTEDKIQLNGVVFNDLIPGNLTGNQFTTVPNFNPNAPGAAGAANLIYNPIDGLLYYRNQNGQISIVAKVGNNLNIGSNNFEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUM2</accession>
    <name>A0A2G4EUM2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="9">RNAP subunit beta'</shortName>
            <ecNumber evidence="9">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 14" type="primary">rpoC2</name>
        <name evidence="14" type="ORF">CP500_022555</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 Zn(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 9">In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="9"/>
    <dbReference type="EMBL" id="NXIB02000233">
        <property type="protein sequence ID" value="PHX53239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53239">
        <property type="protein sequence ID" value="PHX53239"/>
        <property type="gene ID" value="CP500_022555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01324">
        <property type="entry name" value="RNApol_bact_RpoC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012756">
        <property type="entry name" value="DNA-dir_RpoC2_beta_pp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02388">
        <property type="entry name" value="rpoC2_cyan"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 9 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA_pol_Rpb1_3" evidence="11">
        <location>
            <begin position="9"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb1_4" evidence="13">
        <location>
            <begin position="92"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb1_5" evidence="12">
        <location>
            <begin position="173"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb1_5" evidence="12">
        <location>
            <begin position="1151"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1373"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX53239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1392" mass="150579" checksum="275A16F53A58102A" modified="2018-01-31" version="1">MTSNNNSIVFRNRVVDKGQLKKLISWFFTHHGTSRTAQMADRLKDLGFRFATRAGVSISVDDLRVPPSKRSLLDAAEEEIRITEQRYTRGEITEVERFQKVIDTWNGTSEDLKDEVVKNFRATDPLNSVYMMAFSGARGNISQVRQLVGMRGLMADPQGQIIDLPIKTNFREGLTVTEYIISSYGARKGLVDTALRTADSGYLTRRLVDVAQDVIVREFDCGTQRGIKVRPMVDGATVLIPLKERLLGRVFAADVLHPSTGKVVAFENERAVRNQPVTEELALEIGKAQVEEVFLRSPLTCESTRSVCQHCYGWSLAHSQMVDMGEAIGIIAAQSIGEPGTQLTMRTFHTGGVFTGEVAKQERAAFAGIVKFKGLRTRSFRTKHGEEAFVAETGGKLVLESDGSLGANGNSPTHGNSPLHGAKNHKQKTELAIAQGSTVMVSDGQQVVMGQILASVPIAGRAARKTTEKVTTDVASDLAGEAKFADLIPEEKTDRQGNTTRTASKGGLVWILSGEVYNLPPGAEPAVRNGDRVIANSVIAETQLISEHGGVVRIANEREIEIITAQVLLDQAVVQAQTIGGREHYAIETASGQRFSLKTVPGSKVANGEVVAELLDDSYRTATGGIVKYAGVEVHKRGKAKQGYEVVKGGTLLWIPEECHEVNKDISLLLVEDGQYVEAGTEVVKDIFCQTSGAIEITQKNDILREIVIKPGELHGCDRPFLAPGEGQIVNAGQELIPGLVASELSYAECIETPEGPALLLRPVIEFPVPDRPPVPSQTALNPSISLKAVQRLPYKDGERVKSVEGLELLRTQLILEIGTDAPQLAADIELLSDEDGAVAFGIDGSGPAWTEAIAPVTESSLETLDNQDGLVRSKPLRLQLVILESLALRRDLSADPTQGSTNTRLLVTDGQEIAPGAVVARTEILCKATGVVRGIREKPGEPVRRLLIMRDADSITLEVPGIPNVSPGQLLVAGTEIATGVFLAESGQVVKVIAPTEPHDPTKLTLRIARPYRVSAGAVLHVDDGDLVQRGDNLVILVFERAKTGDIIQGLPRIEELLEARKPKEACILAKRPGVAQIEADGDAVELRVVEDDGRIEEYPLLPGQNPIVSDGQRVGAAEALTDGPANPHEILEVYFHVLKERKPTHQAALESFQQVQTLLVNEVQAVYQSQGVDISDKHIEVIVRQMTNKVRLEDGGDTNMLPGELVELRQVEQVNEAMSITGGAPADYVPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFNAYEDLLGVDALGDGALFDDDIRDLPGDGVLDDRTARRAYAIEGGFGVPGAVLTIDDDFEEEVEVGDDDFVAQVDDGAMEAIEADDDFDLGDDDYEDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUM9</accession>
    <name>A0A2G4EUM9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">OrfB_Zn_ribbon domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_022570</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000234">
        <property type="protein sequence ID" value="PHX53234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53234">
        <property type="protein sequence ID" value="PHX53234"/>
        <property type="gene ID" value="CP500_022570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="12"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="7562" checksum="D99276C6D0590D34" modified="2018-01-31" version="1">MTIARESSRRTKSSICGNHRHKMPLKDRVYMCPDFGHKKNRDLNVAKNIDRWFEEIFIPKRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUU3</accession>
    <name>A0A2G4EUU3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_022255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000220">
        <property type="protein sequence ID" value="PHX53301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53301">
        <property type="protein sequence ID" value="PHX53301"/>
        <property type="gene ID" value="CP500_022255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013841475" evidence="2">
        <location>
            <begin position="28"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="75" mass="8065" checksum="0FE890E89233DA63" modified="2018-01-31" version="1">MRNLIQLTTMATLATCLQFNIGSAALAAGQVSNSTGNLTEGRSSWTASENFRFDNYSKYEPEPNGTPNSDSTGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV05</accession>
    <name>A0A2G4EV05_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000209">
        <property type="protein sequence ID" value="PHX53361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53361">
        <property type="protein sequence ID" value="PHX53361"/>
        <property type="gene ID" value="CP500_021890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="229" mass="25980" checksum="BBB916631C547B8B" modified="2018-01-31" version="1">MGLKLDKVIPWGRCLDEYIGMFHLTSADRKLAILDCAGGPASFNAEMTRQGNTVTSCDPVYQFSAEEIAGRIQETYQRVIDGVKANVDDYLWTNIESPTKLGEVRRLAMQQFLEDLPQGIDENRYITGELPILPFENRQFDLALCSHFLFTYSDHFTEVFHLESIREMCRTAAEVRIFPLVKVSGEPSPLLAPIITELKAQGYKVEVQDVSYEFQKGGDQLLRVWSMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV76</accession>
    <name>A0A2G4EV76_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Guanylate cyclase</fullName>
            <ecNumber evidence="1">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_022060</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000212">
        <property type="protein sequence ID" value="PHX53340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53340">
        <property type="protein sequence ID" value="PHX53340"/>
        <property type="gene ID" value="CP500_022060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021796">
        <property type="entry name" value="DUF3365"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011645">
        <property type="entry name" value="HNOB_dom_associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11845">
        <property type="entry name" value="DUF3365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07701">
        <property type="entry name" value="HNOBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="161"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="8">
        <location>
            <begin position="311"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="238"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX53340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="491" mass="54499" checksum="853E47023AB0D45A" modified="2018-01-31" version="1">MHQLISRSLTAISQLVYKRVILAVTILFCVGVAIAMTNMSELSSTLISSQALQNATLYAQSIKEARTLYSSNVVNPLTSAKAINFTHDYNPPKAKVTVPAPATFLIELGQHITQKNPEISVRLYSNYPFPWREKEGGAKDDFEREALTYLTQNPTQKFFRSEEFRGKPAFRYAEADPLTASCVKCHNTHPDSPKKDWKVGDVRGILEITQPLDNITKKTRGGLKNLFFLLAGLSILGISGLSLAISRLHQNAKQLEQRVRERTAQLQETNIELVKEQDKSDRLLLNILPESIANKLKDGQNSIADAFAEVTILFADIVGFTVLSSQISPRELLVFLNEIFSAFDSLTEKYGLEKIKTIGDAYMVVGGLPNPSTNHAECIAEMALDMQEELVKFNKKHNSTINIRIGINTGPAIAGVIGTKKFIYDLWGDAVNTAARMESHGLPGTIQVTKSTYNILQNKYLFEDRGIIHVKGKGEMNTYLLAGRLVSPLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVB0</accession>
    <name>A0A2G4EVB0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Nicotinate phosphoribosyltransferase</fullName>
            <ecNumber evidence="4 8">6.3.4.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_021280</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the NAPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="4 8"/>
    <dbReference type="EMBL" id="NXIB02000192">
        <property type="protein sequence ID" value="PHX53473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53473">
        <property type="protein sequence ID" value="PHX53473"/>
        <property type="gene ID" value="CP500_021280"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041525">
        <property type="entry name" value="N/Namide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041619">
        <property type="entry name" value="NAPRTase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040727">
        <property type="entry name" value="NAPRTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007229">
        <property type="entry name" value="Nic_PRibTrfase-Fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006405">
        <property type="entry name" value="Nic_PRibTrfase_pncB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098">
        <property type="entry name" value="PTHR11098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04095">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17956">
        <property type="entry name" value="NAPRTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17767">
        <property type="entry name" value="NAPRTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000484">
        <property type="entry name" value="NAPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01513">
        <property type="entry name" value="NAPRTase_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7 8" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NAPRTase_N" evidence="10">
        <location>
            <begin position="31"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="NAPRTase" evidence="9">
        <location>
            <begin position="179"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="NAPRTase_C" evidence="11">
        <location>
            <begin position="403"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="469" mass="50505" checksum="61E6392E48822240" modified="2018-01-31" version="1">MKTATESLHHQSFAQIQEDQELCLSSEDYSLLTDLYQLTMTACYVGEGLDGRVASFELFARRLPEGFGYAIAMGLAQVLDYLEKFRFSPAQIAALQSTGIFAGAPDRFWTLLATARFTGDVWAVPEGTAVFANEPMLRIEAPLWQAQLVETYLLNAINYQTLIATRSARLRDVAGPDAKLLEFGTRRAFGPQAAVWAARAALAAGIDGTSNVLAALRLGRKPVGTMAHALVMAVSALEGSEEEAFTAFHRYFPGAPLLIDTYDTVAAARKLADRVNSGEIVLEGVRLDSGDLVKLSQEVRSILPGIPIIASGDLDEGEIAKLKSAGACIDGYGLGTKLVSGSPVNGVYKLVEINGVPVMKEASGKMTYPGRKQIFRHIKNGQILGDCLGLSEEENHNSDSPIALMKLVVKDGKRLYGQESLEAIAKRTAASVASLPAATRQLNNPISPPVEISTDLQNLTNETRQKVSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVD0</accession>
    <name>A0A2G4EVD0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">lpdA</name>
        <name evidence="16" type="ORF">CP500_021265</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="NXIB02000191">
        <property type="protein sequence ID" value="PHX53485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53485">
        <property type="protein sequence ID" value="PHX53485"/>
        <property type="gene ID" value="CP500_021265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="7"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="356"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="184"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="328"/>
            <end position="331"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX53485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="478" mass="50689" checksum="C8719C33CBC2046B" modified="2018-01-31" version="1">MTQGFDYDLAIIGAGVGGHGAAIHAVSCGLKVAIIEAGDMGGTCVNRGCIPSKALLAAAGRVRDLRNAHHLKTLGIQLGSVDFDRGAIANHANTIVSKLRGDLTNSLKRLNVDTIQGWGKIAGSQKIIIETDKGEKTITAKDIILAPGSIPFVPPGIEIDGKTVFTSDDAVRLESLPKWIAIIGSGYIGLEFSDIYTALGCEITMIEALDQLMPTFDPDIAKLAERVLITPRDIETKVGMLAKKITPGSPVIIELADFKTKEIVEVLEVDACLVATGRVPVSKNLGLETAGVETMRGYIPVNDKMQVLAGGEPVKHLWAIGDVNGKMMLAHAASAMGIAAVENICGRDREIDYLSIPAAAFTHPEISYVGMTEPAAKELGKTEGFEVASVKTYFKGNSKAIAEGETDGTAKVIYRKDTGELLGVHIFGLHASDLIQEAANAIAQRDSVHTLAFRVHTHPTLSEVLDEAFKRAAGTGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVI6</accession>
    <name>A0A2G4EVI6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tmk</name>
        <name evidence="5" type="ORF">CP500_022835</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000248">
        <property type="protein sequence ID" value="PHX53187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53187">
        <property type="protein sequence ID" value="PHX53187"/>
        <property type="gene ID" value="CP500_022835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="4">
        <location>
            <begin position="8"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX53187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="220" mass="24723" checksum="C9205310105C5057" modified="2018-01-31" version="1">MDGKLIVFEGVEGAGKTTQMQRLIHWLEAKCFIIKGLVATREPGGTELGKALRSLLLEQSSDELVSDRAELLMYAADRTQHVETFIKPKLERGTMVLCDRFTDSTIAYQGYGRGLDLGLIQQLNEIATGGLQSDLTFWLDINVEAGLTRVRARGKRDRMEQANLEFHQRVQQGFADLARQNPDRIVRINADRPEDEVAHEIQTIFNAKLAAWGYSKSSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVK4</accession>
    <name>A0A2G4EVK4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_020735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000176">
        <property type="protein sequence ID" value="PHX53571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53571">
        <property type="protein sequence ID" value="PHX53571"/>
        <property type="gene ID" value="CP500_020735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="8"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="321" mass="36803" checksum="950246889429B27C" modified="2018-01-31" version="1">MNRTPKYSFVIPIYNEEENLAELYRRISAVMDRMDGPVELILINDGSRDRTLELLRELHAQDSRICYLSFARNFGHQIAVTAGLNFSTGKIVVVMDGDLQDPPELIIDMVEQWRQGYQVVYAQRTQRRQEGWFKRLPAYMYYRILRNLADVDIPTDTGDFCLMDRCVVDVLNAMPERNRYIRGLRAWIGFKQTAVKFERDARFAGDVKYTFSKSFALAMNGLVSFSKVPLQLSIYVGLFAAFVSVLMAFLVLYWRIFSPNSALTGLTIVIMAVFFLGAVQLVSIGILGQYVGRIYEEVKGRPLYTLAEVVGFDPFRQKDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVS0</accession>
    <name>A0A2G4EVS0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000171">
        <property type="protein sequence ID" value="PHX53624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53624">
        <property type="protein sequence ID" value="PHX53624"/>
        <property type="gene ID" value="CP500_020490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="229"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="523" mass="59709" checksum="5468E5B3498C5537" modified="2018-01-31" version="1">MENRVLYVRLPCNPIFPIGVVYLSDHVHKLFPDVEQRIFDVGAVPPLDYAKALDVAVDEFQPTLLVFSWRDIQIYAPVGGRGGNPLQNAFEFYYANNPLIKVRGALGGLRLAISYYTELWRNLGLIKRGLHRARKYRPEARAVVGGGAVSVFYEQLGRSLPPGTVVSVGEGEALLEKLITGEDLAQERCYVVGETVPRDRLIHEKPANIEKTACNYQYIESIWPEFSYYLQDLDFYIGVQTKRGCPHNCCYCIYTVIEGKEVRINPADEVVAEIRQLYDRGIRNFWFTDAQFIPARKFINDAVELLQKIIADGMTDIHWAAYIRADNLTPELCDLMVKTGMNYFEIGITSGSQELVRKMRMGYNLRVVLENCRDLKAAGYNDVVSVNYSFNVIDETFETIRQTIAYHRELERIFGVDKVEPAIFFIGLQPHTILEEYAFKKDILQPGYDPMSLMPWNARKLLWNPEPFGSFFGEVCLEAWQRNSNDFGREVMAILEEKLGCADLEDALTAPIEVKEKQLTSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVV4</accession>
    <name>A0A2G4EVV4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbon dioxide concentrating mechanism protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000165">
        <property type="protein sequence ID" value="PHX53661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53661">
        <property type="protein sequence ID" value="PHX53661"/>
        <property type="gene ID" value="CP500_020255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043886">
        <property type="term" value="F:structural constituent of carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="223" mass="22903" checksum="2302EA80D4B640A2" modified="2018-01-31" version="1">MYLSPLQLSSNFQVCISGDVVVDEGAAIARGVILRADPGSRISIAAGACIGMGAIIHAREGTLEIGAGVILGAGVLIVGSGAIGANACIGAATTLINPCVDKMQILPAGSLIGDGGRQVTLEATVEPKAEPKAEPETPAATTPPVEKPVKETPEVDRTKPQTPPETTSSPESTAAEPPPQPGEVPTILYGQAHINRLLGTLFPYRQSFNKLEENGKTFSDGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW71</accession>
    <name>A0A2G4EW71_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000155">
        <property type="protein sequence ID" value="PHX53785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53785">
        <property type="protein sequence ID" value="PHX53785"/>
        <property type="gene ID" value="CP500_019620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008521">
        <property type="term" value="F:acetyl-CoA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="PTHR12778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="454" mass="50179" checksum="CFB865E3C26AB8BA" modified="2018-01-31" version="1">MEKKHNAGLWVSILYFAQGLPYTVVNLMSVIFLKGMGTSNELIGLTSLLSFPWVLKGLWGPVVDMYSTKRKWILNTEIICAFLFASLAFGVLMPQAIIISVVILTAIAFVSATHDIAIDGFYLNTLNKDQQALFVGVRNTAYRGAVILGSGVLVFFAGKLAEEHLVTGTGSDTKIYQDIPLSFFGSSFNVSALQYGWATAFGICAIIFVLIYLFQRWYLPYPKSHDIEVGAPRKTISFIESFRTYFQQDKIGWIVAYVLIFRLGDALTFKMAPPFLMDKIEKGGLAVSTSDMGLLSGTLGVMFLLVGGLLGGYLIAKQGLKKWMWPTAILQNSTNVLYWMLAINQPGIEWAYVVNSIEQFTYGLGVAAYTVFLMRTVRPEYEASHYAITTAFMAAGVLIPGVFSGYLQASLGYQNYFLMSALAVIPGMMTIFFLPLEDEPKLASMPRPGLDDPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW81</accession>
    <name>A0A2G4EW81_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrogen regulatory protein P-II</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">PII signal transducing protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_019720</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is phosphorylated, these events are reversed. In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is phosphorylated which allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the P(II) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000156">
        <property type="protein sequence ID" value="PHX53781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53781">
        <property type="protein sequence ID" value="PHX53781"/>
        <property type="gene ID" value="CP500_019720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="6">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="112" mass="12557" checksum="BE4C48D5128748AA" modified="2018-01-31" version="1">MKKVEAIIRPFKLDEVKIALVNAGIVGMTVSEVRGFGRQKGMTERYRGSEYTVEFLQKLKVEVVVEDDQVDMVVDKIIAASRTGEIGDGKIFISPVEQIIRIRTGEKNMEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWM2</accession>
    <name>A0A2G4EWM2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000139">
        <property type="protein sequence ID" value="PHX53933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53933">
        <property type="protein sequence ID" value="PHX53933"/>
        <property type="gene ID" value="CP500_018815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="286" mass="31827" checksum="123D81E272C8A200" modified="2018-01-31" version="1">MNLVIRRATHQDIDVCARINYEAFKGISDRHQFPTDFPTLDFATEITGLLINNPLFFDIVAESDGSVVGCGFMDERNPIRGIGPVSVDRTFQSKGTGRKIMKALLEQGKEAQGIRLVQESFNMASLSLYISLGFEVKEPLLLLEGKFRSQPRYDFEVRPLTSEDVDECEALCKRVYGCDRPSEIEYALNHLSPLVATKQARIVAYTCAVSTFGHSVAETEADMQALLLGAAAYSPGEVLCFHLPVRYASLFRWCLQEGLRGLKPLAVMAIGDYQQPAGCCFPSYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWP9</accession>
    <name>A0A2G4EWP9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Photosystem I protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000174">
        <property type="protein sequence ID" value="PHX53597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53597">
        <property type="protein sequence ID" value="PHX53597"/>
        <property type="gene ID" value="CP500_020605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012986">
        <property type="entry name" value="PSI_PsaX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036243">
        <property type="entry name" value="PSI_PsaX_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08078">
        <property type="entry name" value="PsaX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81552">
        <property type="entry name" value="SSF81552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="48" mass="5525" checksum="046278FAFF626153" modified="2018-01-31" version="1">MAEIAKNQLKSESVMKTGNPPYTFRMAWFLGLLGINFLVAAYYFHIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX80</accession>
    <name>A0A2G4EX80_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000129">
        <property type="protein sequence ID" value="PHX54050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54050">
        <property type="protein sequence ID" value="PHX54050"/>
        <property type="gene ID" value="CP500_018200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013579221" evidence="1">
        <location>
            <begin position="21"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="52"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="168" mass="18572" checksum="0B022F9EBA33EF14" modified="2018-01-31" version="1">MYKPLVLMSLGFLAILPNCAQIIPTQSPPQIPMNTNLASTSITDLEKAVNQQINQYRASKKLPPLSVDPRISQQAKIHSENMASGKVKFSHDGFDGRAKAIAIPYQSVAENVAYNMGFSDPVRNAVDGWIKSDGHRKNMEGQFNLTGIGIAKNAKGEYYFTQLFVRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXG0</accession>
    <name>A0A2G4EXG0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000119">
        <property type="protein sequence ID" value="PHX54166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54166">
        <property type="protein sequence ID" value="PHX54166"/>
        <property type="gene ID" value="CP500_017590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="76" mass="8621" checksum="56FECEADFDDBA122" modified="2018-01-31" version="1">MSRTESCGIYTSTIVSPYDEEGLVTGLQQLANCADLRLRMSDSARQRAEEFTWEKVARRLAELVLDRLKSASKIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXK1</accession>
    <name>A0A2G4EXK1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4090 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_017155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54259">
        <property type="protein sequence ID" value="PHX54259"/>
        <property type="gene ID" value="CP500_017155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025149">
        <property type="entry name" value="DUF4090"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13319">
        <property type="entry name" value="DUF4090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="10901" checksum="00A081E97F9B33F7" modified="2018-01-31" version="1">MSEETNSVAQSTTGADAIDVAIASGIDFDGTPIPQAKLDLYEQVMGLEAGRQRSGVSNTMRSRIVRIGVKHLPQAELDQMLIAADFAPLKEKEVAFYYGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXK2</accession>
    <name>A0A2G4EXK2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54265">
        <property type="protein sequence ID" value="PHX54265"/>
        <property type="gene ID" value="CP500_016980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="362" mass="42521" checksum="BBC0492949EBF038" modified="2018-01-31" version="1">MMSQLNEPLKIWINEDLLLPDVRLVPLLMHLSPPETHPELQFWNLLRDELPELVKIHRFTNLADAGKIVVIPHFMSNYYLLKKEGEINKFRRQVLASKRTLVTFSNCMEYKAYQGELFFASATYRDQKEKSIPTPAWIFDIGEKVNIPKPSIPTVSFVGNIEYPSRINSLILRYIKFSDSMINWMACSLFVNRNLNLGRRRLIAQLVRKKIINEVRKAKNLQTFLIERKGDFYTLPLEEKKRQRAEYIESIENNAYLLTMRGDDNGCYRLWEVMSAGRIPVLIDTNGLLPELRGMKWEDFCVIVPFSEVHRIGDYIQTFHDRLSDEDFVEVCRKSRAAFDQLLPHNFVVRILEKIVELKSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXT0</accession>
    <name>A0A2G4EXT0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000107">
        <property type="protein sequence ID" value="PHX54343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54343">
        <property type="protein sequence ID" value="PHX54343"/>
        <property type="gene ID" value="CP500_016655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="62" mass="6742" checksum="8AC9E4D402194ED4" modified="2018-01-31" version="1">MLGFADALPNLQNLLQNLCEKLARALDSEVRSETPQTFANSVLKLGKLLQLMGREAEAIEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXV5</accession>
    <name>A0A2G4EXV5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54308">
        <property type="protein sequence ID" value="PHX54308"/>
        <property type="gene ID" value="CP500_016875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="137" mass="15332" checksum="5C7DF206F4C52773" modified="2018-01-31" version="1">MTSYRLNLPVKLQQEAEKLATLQGISLDRFILWAVAEKVATLNQRNDDAVFPQITYVRGASSELIPVLRGTRLRVQTVVIAAQKWDFSPNQIATEYDLSEVQVNEILAFYAAHSQEIDVSIAAEQIIEPDNSSAIFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXY1</accession>
    <name>A0A2G4EXY1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">IS607 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_016820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54310">
        <property type="protein sequence ID" value="PHX54310"/>
        <property type="gene ID" value="CP500_016820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00397">
        <property type="entry name" value="RECOMBINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="5">
        <location>
            <begin position="54"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="4">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="22041" checksum="9019474E20C7C404" modified="2018-01-31" version="1">MAYIPLRKAVDFLGLHPHTLRKYADEGKIKSIKNEAGQRLYDVESYQRGATRTTVVCYCRVSSPKQRDDLARQVDFMRQQYPDAEIIQDIGSGLNFKRKGLQALLVRFMRGEQLTIVVACRDRLCRFGFELFEFMVQQNGGQIMVLDKTVHCPETELTSDLLAILHDDRCRMHGLRSYSQKIKEDPVIPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY10</accession>
    <name>A0A2G4EY10_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YdcF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54424">
        <property type="protein sequence ID" value="PHX54424"/>
        <property type="gene ID" value="CP500_016200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="47"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="196" mass="22428" checksum="10BF4A4B006C673A" modified="2018-01-31" version="1">MWLRVNLNKRFRKRLRSSQQVRLLVAFLMAFWFSYQHLKGEFQRPEALLVLGGATEREVFAANFARKHPGLPIWVSSGSNREFAEWVFSEAGIQSDRVHLDYRAVDTVTNFTTLVDELRDRGIDSLYLITSDDHMRRAWIIGEIVFGSRGISFKPVAVPSGREPEPLQKAVRDGVRAIVWLTTGYTGANFSQPTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY11</accession>
    <name>A0A2G4EY11_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GUN4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_016205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54425">
        <property type="protein sequence ID" value="PHX54425"/>
        <property type="gene ID" value="CP500_016205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16383">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008629">
        <property type="entry name" value="GUN4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037215">
        <property type="entry name" value="GUN4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34800">
        <property type="entry name" value="PTHR34800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05419">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140869">
        <property type="entry name" value="SSF140869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GUN4" evidence="1">
        <location>
            <begin position="125"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="277" mass="32223" checksum="818ED0C0DEB537C3" modified="2018-01-31" version="1">MPKCPVCDTEYVEEIAVFCSVCGWDLTAYPSSSKPSKIYLKKEEVRLDWAKKMWEFACTQQSWEMKFDELQGELQESAIARSHIQSQLDWVLYRLEQLNPESIASTLLRLEEKIGEIPDKTPPMSEVGMDYRQLTKLLKTGKWQKADEHTWEILLSISLREEEGWLSAADIDNFPCTDLRTIDQLWQQYSNGRFGLSVQQQIWDSVGGKYTEFCDRVGWRVKDNWKYYEELCFRETAPPGHLPITVWRRRACYGAGQLTAAENLIAITERLAACRNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY75</accession>
    <name>A0A2G4EY75_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bifunctional diguanylate cyclase/phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016335</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54410">
        <property type="protein sequence ID" value="PHX54410"/>
        <property type="gene ID" value="CP500_016335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="302"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="355"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="424"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="480"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="555"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="640"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="816"/>
            <end position="1072"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1074" mass="121390" checksum="AF73FC5934FBDD40" modified="2018-01-31" version="1">MLAIKNTRQLGRLVFIFFDKPDNYMNASESETQLSGCNHPKVSTAAQLDEDLLENILAGIDRATGPEFFDALVRHLESALGVRSVIASKLVKSDDRTSCPKLQVISFWSDRQRQPNFECDTANTPEAMAIKQGMYSCPDNLLETFPQDHRPLATGVCSFLGVSLTNSYGKCLGTICLFHDRPLAAEKVAQFRLILKIFASRASAELERGRLQAQLHTVEAKYCALVEQAPTVTYISPINSPSIKLEISAQIETLLGYSVAQWEADPQLWLKLVHPDDRDRVLVESATLQFTDEENIPSNQPIVSEYRAIARNGKVLWFRDRAIAVWDEASQSFIRQGAMFDITETKVTANALLESELRYYTLEKILPVGIFRADASGKCLYVNERFLEMVGLTLRETLGEGWAIALHPKDRDGVLQQWYRAVRQQLPFQLEYRFYQGDRTIWVFSQAVPEIAKTGEVLGYIGTLTDITDRKQAEEGLQRAEEKYRSIFENASEGIFQTTPDGRYLSANPALAKIYGYDSPSELIAQIQNIYRQLYVEPNRRTEFLRAIEKHSSVSEFESQVYRADGTAIWISENARSVRDAGGILLYFEGTVEDVTDRKITKEKLVHDALHDILTGLPNRALFMERLSEAIELSKHHDDFWFAVLFIDLDRFKVVNDSLGHLVGDQLLIAIAGRLKICLRHGDTVARLGGDEFAILLNNIKDRNDATHVAERLQTELSEPFYLNEYQVFSSASIGIVCSGLPQHQLEKSGDTNDIETDLSTDFANSAFPNIQLQVLYDKPEELLRDADAAMYHAKASGKARHEVFDLSMHTRAVALLQLENDLRHALERQEFQLYYQPIICLTSGTISGFEALLQWYHPMRGLVATADFMSVAEETKLIIPIGWWMMRSACLQMQQWHQQFPEHPNLTVSVNLSNQQFKQPDLIERIREILQETQLNPGSLKLEITESVIMENAESAASVLGELKSLEVQLYIDDFGTGYSSLTRLHTFPTDALKIDRDFVSRMTEDEGNEAIVQTILILAGHLGMNVIAEGIETIEQLNLLRALQCEYGQGYFFSKPVDSKTATMLVASKPEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY96</accession>
    <name>A0A2G4EY96_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ShlB/FhaC/HecB family hemolysin secretion/activation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_015810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54502">
        <property type="protein sequence ID" value="PHX54502"/>
        <property type="gene ID" value="CP500_015810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005565">
        <property type="entry name" value="Hemolysn_activator_HlyB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013686">
        <property type="entry name" value="Polypept-transport_assoc_ShlB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08479">
        <property type="entry name" value="POTRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03865">
        <property type="entry name" value="ShlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POTRA_2" evidence="4">
        <location>
            <begin position="133"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="3">
        <location>
            <begin position="213"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ShlB" evidence="2">
        <location>
            <begin position="273"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="626" mass="68231" checksum="939F778129068D2B" modified="2018-01-31" version="1">MTYRSNKLLIFIVIFAFLLLGIPAKATASKIENSLSNLDNLELPNPQNLPTEIDRDSQLISNPVASVLFNPSTVNSQQSTVNEISQLPNPIQPREPELPAPGPPQPPELSPLQPTQPTPAEGEVRPEIPGTIRVDRFEFEGNTAFSDRELAEITQTFVGREITFAELIAVEAAVTQKYLAAGYINSGAVIPANQSFPRQGAVVKIQIVEGGLEEIVITGNRRLNASYVRSRLAIATKKPLNRDRLLQALQLLQLDPLIANISAELQAGSSPEKSRLEVRVKEADSFSGEVFTDNNRSPSVGSFRRGVRINQANLLGLGDGLEVSYANTDGSNEINGSYTIPVNPRNGTIRLAVGAASTNIIEEPFDAAGIEGKSRTYELSYRQPIVEKPDRNLALGVTLSRQESNTSLSGEPFPLSAGANDRGETRVSAVRFFQEYVQRSSNQVFAARSQFSIGTNLFGATSNNSGPNSRFLAWRGQAQYVRLLAPETLLIVRSDIQLADRPLLSLEQIGIGGVQSVRGYRQDLLLTDSGAIASAEVRIPIWRVPKVKGLLQVAPFIDLGVGWNHSGEKANPDSDKLLGAGVGLLWQMGDRFNARLDYGIPLINVGGGDRTFQEKGIYFRINYFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYE8</accession>
    <name>A0A2G4EYE8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_015485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000092">
        <property type="protein sequence ID" value="PHX54554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54554">
        <property type="protein sequence ID" value="PHX54554"/>
        <property type="gene ID" value="CP500_015485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="11037" checksum="016D5A4CF2BCE229" modified="2018-01-31" version="1">MSIYVGNLSYQVTQEDLTSVFAEYGAVKRVQLPTDRETGKMRGFAFVEMGSELEEAAAIEALDGAEWMGRDLKVNKAKPREDRGPNRSGGGGSFNRGGGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYJ0</accession>
    <name>A0A2G4EYJ0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000089">
        <property type="protein sequence ID" value="PHX54592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54592">
        <property type="protein sequence ID" value="PHX54592"/>
        <property type="gene ID" value="CP500_015245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="187" mass="20120" checksum="22EBA819593134E9" modified="2018-01-31" version="1">MKIKIYPIAIGLSIALMTAVISRRVEITISNNSNLPNNLPRTATVFPPATTATPNRVIPAKPKPTSIPVEPEELKNASSIPANVEATGTLRVSNRSEHPVRVALLAKGETEKSYSKPAHWDFAPGEGGGKGLMLSLPQTKLKLKQGDILVVFAQDGSRRYWGPYVAGETASPAWNSKAGEWQLTLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYS3</accession>
    <name>A0A2G4EYS3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000085">
        <property type="protein sequence ID" value="PHX54669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54669">
        <property type="protein sequence ID" value="PHX54669"/>
        <property type="gene ID" value="CP500_014895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030655">
        <property type="term" value="P:beta-lactam antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045155">
        <property type="entry name" value="Beta-lactam_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000871">
        <property type="entry name" value="Beta-lactam_class-A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000667">
        <property type="entry name" value="Peptidase_S13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35333">
        <property type="entry name" value="PTHR35333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13354">
        <property type="entry name" value="Beta-lactamase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00922">
        <property type="entry name" value="DADACBPTASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase2" evidence="2">
        <location>
            <begin position="214"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="434" mass="47848" checksum="CD40FCFEEFE64A62" modified="2018-01-31" version="1">MLGIGRFLSATNKTVAVVAGIGLIQVLTIASSFSQSSNQRSLDELYKIRDRIVTQLEQPPSPSPEPTLLSRLVPFTANTSEKLLQELQSVEVQILVEQRANDNFQQAVRLADQAVEAGREQNQSLESSQKIKFLWQQALDNLSEVPKNSFLASLTASKIEEYGKNLTAATFQVKQAKSDFLGSVARESGLSDQASIGICQLSRDCIHLRGNSPPVSPASLIKLPIAVALMQKVEHEKISLNKPVFVDPGNFTEDSSTQIVSDQNYPLQTLLEEMIDRSSNIATNQLIDYLGSDYINQFLENRGYQVTRVNFKLMGKNIMPTNPGTGANRVTVNELTEMMVQIYNGETPGAKMLVETLNRQYDRNLGFAALQGTKAQWLGEKTGENSLVLGTTLAMSIDGEAYMMTVIDKSSGSDIEMRRSIAKIADYIARNPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYS8</accession>
    <name>A0A2G4EYS8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyanoexosortase A system-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000084">
        <property type="protein sequence ID" value="PHX54674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54674">
        <property type="protein sequence ID" value="PHX54674"/>
        <property type="gene ID" value="CP500_014720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026411">
        <property type="entry name" value="Cyanosort_A_assoc"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04153">
        <property type="entry name" value="cyanosortA_assc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="222" mass="25144" checksum="D9A905B8C96D20F6" modified="2018-01-31" version="1">MAITDWKTARISLLAVTFTVVLLVLGKLTFYPSVGTPAATTFELPETVPVADWQIKKSTPLKISDTSQIKVGRKYDYQKNNLALEVEMRYVVGTIGDVAGLAKGNTVLKSSPAKLELANAEKVGFYGILQFQNRLYLSSCINPSGYATVTSNQFRYNRNTSDWNLNRILFWLLGRGNIQDQRCLWTQMSVPLDQTTPQDAKKILENAWVSWYGWWQPRFPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ11</accession>
    <name>A0A2G4EZ11_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54763">
        <property type="protein sequence ID" value="PHX54763"/>
        <property type="gene ID" value="CP500_014365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="113" mass="13311" checksum="63332CD3533026C6" modified="2018-01-31" version="1">MDKIENYRTLIKKILSEYDRLIANQATANTEMLLAFDEKHDQYLWFQVGWQQNKRVRGITVHIQIKNNKIWIEEDWTEEGIANELLKEGVSQSDIVLAFHHPDDRPLTDFAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ28</accession>
    <name>A0A2G4EZ28_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adenylate/guanylate cyclase domain-containing response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_014410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54772">
        <property type="protein sequence ID" value="PHX54772"/>
        <property type="gene ID" value="CP500_014410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="5">
        <location>
            <begin position="177"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="353" mass="39291" checksum="8BA8FAF2B978C2C9" modified="2018-01-31" version="1">MKGDESSVLVVDDNEVNRDLLARRLQRQGHVVTAAEDGLQALELMRSLPFDLVLLDIMMPHMNGYQVLENLKADERLRHIPVIMISAVDDIDSIVRCIELGAEDYLSKPFNPVLLKARISACLEKKRLRDQEQAYSQELAEEKEKSERLLLNILPQAIAERLKQGETTIADSFSDVTVMFADLVGFTKLSTHLSPAELVELLNQIFSEFDELADRYELEKIKTIGDAYMVVGGLPTPSQNHAEAIASMAIDIQAAIAKMRTKGDQPLSIRIGINTGPVEAGVIGTKKFTYDLWGDTVNVASRMESLGVPGGIQVTVATYERLRDKYIFEDRGLLQVKGKGDMMTYLLLGRKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ48</accession>
    <name>A0A2G4EZ48_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2232 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_014500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54748">
        <property type="protein sequence ID" value="PHX54748"/>
        <property type="gene ID" value="CP500_014500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018710">
        <property type="entry name" value="DUF2232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09991">
        <property type="entry name" value="DUF2232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="257" mass="28413" checksum="1736A3A8F47EBA2E" modified="2018-01-31" version="1">MSDFLSSNSASNLNNSSNTNSGQQTDAISDLSRDRTNPVPDDTDTTSDTAKAAPLRLVETAFLASTASLIWLVNYYFPLGPLLRVFFPIPIALVYLRWGKRAAWMAALVSGLLLSVLMGPTRSILYVIPFGIMGVALGGLWRRKTTSWAVSIGLGGLIGTFGFFFRFWLLSALVGQDLWVYVTAQVAEMVEWVFVKFGWLSVPSLNTIQAIAAAMILVNNIIYLFVVHLVALLLLDRLGNPIPRPPRWVQILIDYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ80</accession>
    <name>A0A2G4EZ80_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipid-A-disaccharide synthase</fullName>
            <ecNumber evidence="2">2.4.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_013915</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a lipid A disaccharide + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:67828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="ChEBI" id="CHEBI:176338"/>
            <dbReference type="ChEBI" id="CHEBI:176343"/>
            <dbReference type="EC" id="2.4.1.182"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.182" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54821">
        <property type="protein sequence ID" value="PHX54821"/>
        <property type="gene ID" value="CP500_013915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008915">
        <property type="term" value="F:lipid-A-disaccharide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003835">
        <property type="entry name" value="Glyco_trans_19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30372">
        <property type="entry name" value="PTHR30372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02684">
        <property type="entry name" value="LpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00215">
        <property type="entry name" value="lpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="390" mass="42982" checksum="E108A1DDFFD92BBD" modified="2018-01-31" version="1">MKIFISTGEVSGDLQGALLVTALKHQAAAIGLDLEIVALGGQRMAEAGATILADTVGIGSMGIVEALPYLWPTMKVQKKAKQYLKDSPPDVVVLIDYLSPNLGIGSYIRRHLSSIPVLWYIAPQEWVWSISPRNTALIVDICDRILAIFPEEANYFQKKGAQVSWVGHPLVDRMQSAPSREVARKTLGIPPEQVSVALIPASRGQELKYLMPVIFEAAQIIQAKLPEVHFWIPLSQSAFRSQIETAITDFGLRATLLENQTLEILAASDLAIAKSGTVNLELALLDVPQVVLYRVSPITAWIAQHLLKFSIPFMSPPNLVQMKPIVPELLQDEATAENIVFHALELVQNGDRRQQTLDGYREMREHLGEVGASDRAASEIMKYLKLNVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ92</accession>
    <name>A0A2G4EZ92_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_014170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000077">
        <property type="protein sequence ID" value="PHX54808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54808">
        <property type="protein sequence ID" value="PHX54808"/>
        <property type="gene ID" value="CP500_014170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="110" mass="12376" checksum="DBBE96664D1F6435" modified="2018-01-31" version="1">MAKIKFHLDENITLAIGNGLRRRGIDVTTTPEQGMIGQSDEQQLAFSLSQERVIFTQDTDFLRLHHAGLSHAGIVYCPQTSKSIGEILQGLVLIWEVLNAEEMNNHLEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZL9</accession>
    <name>A0A2G4EZL9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000071">
        <property type="protein sequence ID" value="PHX54938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54938">
        <property type="protein sequence ID" value="PHX54938"/>
        <property type="gene ID" value="CP500_013350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021147">
        <property type="entry name" value="DUF697"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05128">
        <property type="entry name" value="DUF697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="74"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="482" mass="52093" checksum="CEF31299DBBC4C8E" modified="2018-01-31" version="1">MTEDSDFSNVDRELDNTILSFSDIQAELNLRHAKDALRDIVENLDLTPQERTGLEPEIGGLQKMLDKLERACVQIAVFGMVGRGKSSVLNALLGQNVFETGPTHGVTRTTTIGEWDVGEGIDDNLGDRFSPIIYRLSQVELIDTPGIDEVDGETREILARRVAKQADLILFVVAGDITKVEYEALSQLREAGKPMLLVFNKIDQYPDADRLAIYHKIRDDRVRELLSPDEIVMSAASPLTASAVRRPDGTMGMKMTRGLPQVEDLKLKILEILDREGKSLVALNTMLCTGDINEQLVQRKMEIRDNAANRIIWNGVMTKAVAIALNPITVIDILSGAVIDVVMILTLSKVYGIAMTEAGAVQLLQKIAISMGGITAGELVANFGLSSLKGLLGLATPATGGLALGPYLSVAATQAAIGGVSCYGIGQVTKAYLANGASWGDDGPKAVVSKILSSLDEDSILNRIKDELRAKLDLRGVEKQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZN3</accession>
    <name>A0A2G4EZN3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate/guanylate cyclase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54974">
        <property type="protein sequence ID" value="PHX54974"/>
        <property type="gene ID" value="CP500_013205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="251"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="415" mass="46041" checksum="83746DAEFBAE7117" modified="2018-01-31" version="1">MKNRSIETAKSSLKSKNVWESRLQGSRTSAFLSEVLSNSGHFLILKSLSDLILAGLFKFITDPTEYLLIVAMLVQAWYLSNSKCHRFWGNLICVGIYTLIDVPIDGLDFFQNPTHVVFWLFSLMIAILQGLRFHWAKGIDDWLIPLESLVRALMVVAFYVVIGIKSQYLIANLELIVTFSRTATHWFLTWSMVFIGLLLGLQSVQIFKQRKQLQKTAQLLGNMAEWGMGSHVVDTALNNPAGLAFQKCDRTILFMDIRGFTSWCEKTSPETVAAVLNEYYRCVEPAAAKFQPLRITFTGDEIMAIYATPQQGIAAAKSMSKAALEMLELYGIGAGCGVHCGSVIEGLFGGEDVRTYTVIGDVVNTAKRLESATPGGAITISDAVYQRMSQNLRVEPCEPIAAKGKTAALIAWRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZP1</accession>
    <name>A0A2G4EZP1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54975">
        <property type="protein sequence ID" value="PHX54975"/>
        <property type="gene ID" value="CP500_013210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="21554" checksum="5A6946A120595D07" modified="2018-01-31" version="1">MKKITILSIALLTFAVTPELSHVGLSLSAIGQPKTPQPPKKDDPKNLGYVSPEFAEKVSQQEIDQINANVETLLLTKSCIRCDLRGVKLVNLTLKNPIVTGADLSDANLSGGTFEIADFVNTNLARTDLSGSVLIGARISNTNFRKANLTNTNLDGADLRFADLRDANLSNTNLRNANMDGASLDRASMGGTTMPDGRKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZQ3</accession>
    <name>A0A2G4EZQ3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_013280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54989">
        <property type="protein sequence ID" value="PHX54989"/>
        <property type="gene ID" value="CP500_013280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="287" mass="32068" checksum="30018D6F2A4DAB7D" modified="2018-01-31" version="1">MLNQISQPYQQRENTMTQRVLRQSNPSVSKHLRQTVPQRHWLELAEYASLAASGVGSLAVALSGQAFYGVAPLTLALSLNVANRYRFEQQVRVYQNSEIAEVQKSVNKIEKTAATVILKVRKQLSTDIEALRQQMAALPRPESFEDSIDVEEQLLSLGQSVASLQEIVASAVIDVRQQVSQQLLHLSVGEPTNLEAIEEAIEELQSATQLLGETSITQDDWEGVNTRFLEIQKVIANLQSQLQAQAQQSGDLSSFKAQIDNLEHEHEEVVKPHLQRLITVVKQLQNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZR6</accession>
    <name>A0A2G4EZR6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55006">
        <property type="protein sequence ID" value="PHX55006"/>
        <property type="gene ID" value="CP500_013065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="3"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="183" mass="20169" checksum="D681D596D6CB6455" modified="2018-01-31" version="1">MSIRLYVGNLPKELDRQELQDVFAPEGESVTTKVITDRKTGKCRGFGFVTVLTDEQADQVIEKYNGLMFKENPLKIEKALPRSKGKSDKGEEDQQQSPQSPQLASVSAPIQGQPQQQRREASPSQGGGGSGKSSRRRDNNKSRRNPAATTSSNVDSGSVQPDPRWANALEELKQRLQEAQTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZX6</accession>
    <name>A0A2G4EZX6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-isopropylmalate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000066">
        <property type="protein sequence ID" value="PHX55070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55070">
        <property type="protein sequence ID" value="PHX55070"/>
        <property type="gene ID" value="CP500_012670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011827">
        <property type="entry name" value="LeuD_type2/HacB/DmdB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02087">
        <property type="entry name" value="LEUD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="2">
        <location>
            <begin position="66"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="181" mass="19694" checksum="119318C9876EF11A" modified="2018-01-31" version="1">MSKSISGQIFVVDDNIDTDQIIPAEYLTLVPSKPDEYEKLGSYAMIGLPDRYGKFMEPGAMKTRYQIIIAGENFGCGSSREHAPIALGAAGVEAVVALSYARIFFRNCSATGELYPIESGDRLCDVFATGQEVTIDFTTGQIINHTLDRTYHLKPLGEVGPVIDAGGLFDYARQTGMIATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F008</accession>
    <name>A0A2G4F008_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55091">
        <property type="protein sequence ID" value="PHX55091"/>
        <property type="gene ID" value="CP500_012515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8292" checksum="F2165603A18A6FAE" modified="2018-01-31" version="1">MALESKRFRGMFKPGEIVQLKQPCFTPGRLFEPGKYQVADLPDVAFDMGLVDHLPQVKGNSSQTVNPDKEQEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F022</accession>
    <name>A0A2G4F022_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000065">
        <property type="protein sequence ID" value="PHX55105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55105">
        <property type="protein sequence ID" value="PHX55105"/>
        <property type="gene ID" value="CP500_012585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7354" checksum="4D0A9C5C4E963F74" modified="2018-01-31" version="1">MGIGNWELGIGNWELRIGNWESGIGNWELGIDDYFESIVRRCVTIDSKSLTNYQSPTSIAILNHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F042</accession>
    <name>A0A2G4F042_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1361 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000064">
        <property type="protein sequence ID" value="PHX55123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55123">
        <property type="protein sequence ID" value="PHX55123"/>
        <property type="gene ID" value="CP500_012495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009793">
        <property type="entry name" value="DUF1361"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07099">
        <property type="entry name" value="DUF1361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="273" mass="31243" checksum="80A450E014B2BF31" modified="2018-01-31" version="1">MDLIIEALRAMGHNVRWMSWNLFLALVPLAISFWLFRKPRSRWLMWGTGFLLGATFLPSMPLFFFYLKHILQDLGKTYVLGAIAITLALMAVDIWVLGQRGVRSLRWWAGFLVFIAFLPNAPYVLTDIIHLIEQIKQGPSVWVVTLALIPQYLAFMLAGLEAYVLSVMSLGYYLTQQGWGKFVLVTELTIHTLSAIGIYLGRFIRFNSWDLITNPDALVNTVMNDLIGKRPVVVMAATFVVITSLYWLMKQVSLGISHRFYYHQLQSEFSGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F083</accession>
    <name>A0A2G4F083_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Bacitracin ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_012370</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55171">
        <property type="protein sequence ID" value="PHX55171"/>
        <property type="gene ID" value="CP500_012370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005890">
        <property type="entry name" value="NO3_transporter_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01184">
        <property type="entry name" value="ntrCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="42"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="75"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="297" mass="33500" checksum="25041F0FE0C2933A" modified="2018-01-31" version="1">MTGHDITYNSLTSSQPMINTTKNQTDTKMSNQKVNDRRQPFLVIDNVYKSYPNGYRALENVNLTVAKGEFITLIGHSGCGKSTLLNMVSGFSHPSEGSVTMNGQRITKPGPDRMVVFQGYALLPWRTVFENVYIAVNAVFPNKSKVEKNAIVNEHLAMVGLTEAAEKRPPQISGGMKQRVSIARALAIRPEVLILDEPFGALDAITKEELQEELLKIWNDHRCTVLMITHDIDEALFLADRLVMMTNGPSATIGEVLEIPFPRPRDRVQMMEDPEYYNLRNYALDFLFHRFAHDEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0B2</accession>
    <name>A0A2G4F0B2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YggT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_011940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YggT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000061">
        <property type="protein sequence ID" value="PHX55204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55204">
        <property type="protein sequence ID" value="PHX55204"/>
        <property type="gene ID" value="CP500_011940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="PTHR33219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="YGGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="94" mass="10514" checksum="FB5502487362F08F" modified="2018-01-31" version="1">MTGITVTSWILGSVLVVMTLLFIFRIVLTWYPQVNLSKLPLSLIAWPTEPFLVVTRKIVPPIGGVDMTPIIWVGICSLLREMILGQQGLLTMMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0P7</accession>
    <name>A0A2G4F0P7_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Potassium-transporting ATPase ATP-binding subunit</fullName>
            <ecNumber evidence="12">7.2.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">ATP phosphohydrolase [potassium-transporting] B chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-binding and translocating subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-translocating ATPase B chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">kdpB</name>
        <name evidence="14" type="ORF">CP500_011380</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O + K(+)(out) = ADP + H(+) + K(+)(in) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.6" evidence="12"/>
    <dbReference type="EMBL" id="NXIB02000056">
        <property type="protein sequence ID" value="PHX55339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55339">
        <property type="protein sequence ID" value="PHX55339"/>
        <property type="gene ID" value="CP500_011380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02078">
        <property type="entry name" value="P-type_ATPase_K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00285">
        <property type="entry name" value="KdpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006391">
        <property type="entry name" value="P-type_ATPase_bsu_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43743">
        <property type="entry name" value="PTHR43743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01497">
        <property type="entry name" value="kdpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 12" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 12" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="271"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="606"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="671"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="12">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="395"/>
            <end position="402"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="537"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX55339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="697" mass="73284" checksum="A23F03C951189AD4" modified="2018-01-31" version="1">MASSNTPDSQKSRRGGSRESRRHTPKANTKGLYERAFKQAFVKLDPRVMLKNPVMFVVWVGTIVTALLTIDPSLFGPVPGKNQVIFNGLVTFILFFTLVFANFAEAVAEGRGKAQADALRSTKADTTARKLLPDGSTQEVSSTSLRRGDQIKVLAGDVIPADGEVIAGVASVDESAITGESAPVLKEPGSDVASSVTGGTRILSDELTLRVMADPGKGFLDRMIALVEGAERTKTPNEIALTVLLAVLTLVFLIVVSTIPPVGNYVKTPVGVVTLISLLVALIPTTIGGLLSAIGIAGMDRVAQFNVIATSGRAVEACGDVNTLILDKTGTITLGNRLAEEFIPVNGHSLEEVASIALAASLFDETPEGKSIVRLAEKLGATVEFDRTNATGLDFSAKTRMSGTDLPDGTEVRKGAVEAVKGFVRSRGGNIGPDLDEAYERVSRLGGTPLGVCQGNDIYGIIYLKDIIKPGIRDRFDQLRKMGIRTIMLTGDNRLTASVIADEAGVDDFIAEATPEDKIDVIRKQQAEGKLVAMTGDGTNDAPALAQANVGLAMNSGTQAAKEAANMVDLDSDPTKLIDLVTIGKQLLITRGALTTFSLANDIAKYFAIIPAMFAPVGALNVMGLASGQSAVLSALIYNALIIPALIPLALTGVKFRPLSANQLLQRNILIYGLGGAVAPFIAIKIIDVLITAVGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0U0</accession>
    <name>A0A2G4F0U0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRISPR-associated protein Csc3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55366">
        <property type="protein sequence ID" value="PHX55366"/>
        <property type="gene ID" value="CP500_011245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="894"/>
            <end position="915"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="915" mass="103075" checksum="271D3BE0161AEF51" modified="2018-01-31" version="1">MSRKSLLFDEELTTLDHRYFSEVRPRLYKLHTSHGQYGTRKGRTLAEHLDSACQFVLTVSKIAGVPDDKRACILAATAVHDLNKLTDENDKRNVKALARDRTFLLQQLDRACVAKFAQTESELELVRRLVERHSGHSASDGMRFLPEDPNIKRWAAMLIGGDLFDLGIEENKRIRKVETELTVALQRDSKLFHVSLSEDRGYLTSLLLSACEEVLHDRNLHTLAIDPNGQIFVGEAFPDGDLSLFIAQKWQKKIDRVFSSNVEQLVNATKDGIKIDPQAIQQNPEATLDEVDKLLVKKASGYKVEKVAKDIEKYGGDAGENAVTTAAAVGLHPVSNADEFAISEGLKTAYLSYRAAALSPKDVWDRIATQVGLSPEQRSALEPFNAQYGRCLFAAKSIEGDREQMLKKVFAALEDSFQLRGKAEEIEVSAELVNAVRQLLNFSTPANWQGFNELTAYIEANPRQRCSLGTTSLQIGELSSPKMPPGTKVQAFSNRLPGGMIAEPKRRADNLSALGYQLMAVGANFPNAVKQDPLYLHFALPKGSSVELRTIWQNFLKNTAAKNEDGTVTVDEIKLYRENEMVFQSNKMVGLALPKRPEFINSTVTIPVLWGEVNNSVALLKSLRLALEMSLAFEFGFPFVLGANLEVEPTWDFFGKVEGISSSLQPLLGSGQYRRNGHLSKEERRTAVTAEQVLERLRCIGKLAISVASIQKKDDCLYDLARAATRPLSFYYVLLRWLLREQDDPNLEAIWSRIKEPLNTLLRSLMSEEHDRVSSYLKQAAHIAEFAKLRGSSFRRTAQTEPFSEFIKAVRSRKSHMDWDTVFAALVQQYHNRLDRIREHGVGATKYEQVKQFYQVLQQLFEQVYHSRPERLLTDSKTLEAAYLFFLQEARQELKSKTESESTSKTESETTSVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Z1</accession>
    <name>A0A2G4F0Z1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000054">
        <property type="protein sequence ID" value="PHX55408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55408">
        <property type="protein sequence ID" value="PHX55408"/>
        <property type="gene ID" value="CP500_011090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="PTHR13355"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="142" mass="16565" checksum="0DEFFBBAF988B6D4" modified="2018-01-31" version="1">MTDTLDQYRIVETLTESQVSDLMELYKNEFWCDKRTREDVVKMLAATDVIIGLVDEGDRLIAFTRVITDFVYRGTVFDVIVHPTHRKMGLGVKLMDLVVNHPKLQAIETLGLHCLPKMIPFYERWNFTDDVGDLKFMKRQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F119</accession>
    <name>A0A2G4F119_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55446">
        <property type="protein sequence ID" value="PHX55446"/>
        <property type="gene ID" value="CP500_010720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="77" mass="8652" checksum="FCBEB609EF28C615" modified="2018-01-31" version="1">MVGNNAWMQNIKEWIEQNHPNLVTTGYQITSSDTTDYNCIAWRADAAHLLCLAENEGKLKHPGVKGRSTKRLQLGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F187</accession>
    <name>A0A2G4F187_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000060">
        <property type="protein sequence ID" value="PHX55227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55227">
        <property type="protein sequence ID" value="PHX55227"/>
        <property type="gene ID" value="CP500_011855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013834789" evidence="1">
        <location>
            <begin position="31"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="238" mass="25070" checksum="AE0CAD81D78C8207" modified="2018-01-31" version="1">MKIILKLKKIVVAVLAIALCTLCLTPPVMAATAEDVSHLLKDNWCVSFLWKHCDLSGVDLRGANLEEANLSGANLSGANLSGANLKDADLSDADLSGANLANSDIFGTDLSKANLTAANFTRTRLWDANLTLANLTGANLQDANVLYSRLWGCNLTKANLTDATLHGTDLRYANLGKSNLTNADLQSFFSRGSKQVTNLSNANLEGAILTGANLKGAVLAGAIMPDGSINEEIAINLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1L3</accession>
    <name>A0A2G4F1L3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_009585</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55653">
        <property type="protein sequence ID" value="PHX55653"/>
        <property type="gene ID" value="CP500_009585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="13">
        <location>
            <begin position="16"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="11">
        <location>
            <begin position="173"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="12">
        <location>
            <begin position="301"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX55653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="382" mass="43490" checksum="033DDC8DE2F434A0" modified="2018-01-31" version="1">MSYLAECTPWGATARKSKKIRLFLNPEQKAILKQWFGVSRYVYNTTIKYLQQPGTKANWMSIKTEILNGLPDWAKPVPFQIKSIAIKDACGAVKKAKADFKKTGKICSCKFRSRKDTKQSLYIPKSAIGTKGIYPTKLGQSKLKEALPKGFSDGRLTLAYGEYYIVVSEELQPRQTDNQGRVVALDPGVRTFMTFFSESSYGWLGNDSNLLIQKLCFRLDKLISRMSKTNSPQRKRLKKAADRLKSKIQHLVKELHHKTAKFLVDNFDVILIPSFESSQMVSKSRRKIRSKTVRQMLTLSHYQFKKHLEWKAWEQGKVALTSINEAYTSKTVSWTGEVKKIGGSRTIKDSDGNQMNRDLNGARGIFLRALVDTPWLKSCLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1R9</accession>
    <name>A0A2G4F1R9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55713">
        <property type="protein sequence ID" value="PHX55713"/>
        <property type="gene ID" value="CP500_009470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="267" mass="30335" checksum="D78D7490444A1B37" modified="2018-01-31" version="1">MNFRTFTDMSKWGILVKVLPLTALFCLAKWIAHQMQWEFGKFDSQVGSLLAAVTFILAFMLNGTLNDYRTSEDMPAQIANAVETIQDTNLFIAARKPDYDPTLLTEGLAEILKSVLLCLKQGQPFIRVENAVTNLNQLLAEFSKFCEIPSISRLQGEQAKIRLMIDRIQRIRDTDFLASAYGLLHLLIIASSSALLITRTDDFNTNLIVSCFLFTSFMYLLLLVYDIDNPFEYNGTSSADIDLSSLERSYHQLRERLLNDDEPKIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1T3</accession>
    <name>A0A2G4F1T3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CoA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000043">
        <property type="protein sequence ID" value="PHX55730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55730">
        <property type="protein sequence ID" value="PHX55730"/>
        <property type="gene ID" value="CP500_009220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032875">
        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13607">
        <property type="entry name" value="Succ_CoA_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA_binding" evidence="2">
        <location>
            <begin position="2"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="298" mass="31283" checksum="3CE0818EEDE3663F" modified="2018-01-31" version="1">MNLTPESKVLIQGITESPASTLVGLMMKAYGTNVVAGVSPGRGQQELEGIPVFDLVEQAVATVGHIDTTVILVEPYWVLDAALEAIAAGIRQIAIVTEGVPPLDMVRLVRKAEATETLVIGPNSPGIIVPNKLLLGTHPKEFYTPGPVGIISRSSTLTYEVALELTNAGLGQSMAVCIGCDAIVGSSFMQWLQILDEDETTEAIVLVGEVGGWSEQAAASYIAEAIDKPVVAYLAGLYAPKGPSLGHAGILISSRTAARTAFGVTAENKMAAFEEANIPVASRPSEVPKLINKLLKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Y5</accession>
    <name>A0A2G4F1Y5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_009020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55771">
        <property type="protein sequence ID" value="PHX55771"/>
        <property type="gene ID" value="CP500_009020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="165"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="292"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX55771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="386" mass="44086" checksum="CFBC2ECE6559A83D" modified="2018-01-31" version="1">MIVLEFKLKGKAEQYRIIDEMIRTAQFVRNKTLKHWTENQGIKLVDLYKQCAIMAKEFEWAGKLNSMARQASAERAIFAIQRFFANCKAKKPGKKGYPQFKKHTRSVEYKTSGWELSTDKRCLTLKDGFAAGKFKLVGSRDLHFYAPDEIKRIRIVRRADGYYAQFCINVERKEEAVSTGKAIGIDVGLNHFYTDSDGETVTNPRYLRKSEKALKRLQKRVSRKKKGSKNRKKAINKLGRKHLKVSRQRKDFAIKTALCVVKSKDFVAYENLQVRNMVKNHKLAKSISDAAWSQFAQWLEYFGKVYGKIIIAVAPQYTSQECSNCGNLVKKTLSTRTHICGCGTILDRDHNAAKNILIKGLKQAKINLNTAGHAEIHAWGQVISTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Z1</accession>
    <name>A0A2G4F1Z1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phycocyanin alpha phycocyanobilin lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55784">
        <property type="protein sequence ID" value="PHX55784"/>
        <property type="gene ID" value="CP500_008835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03130">
        <property type="entry name" value="HEAT_PBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="224" mass="24578" checksum="4C6FE82CBB9ED0B4" modified="2018-01-31" version="1">MTILSLTEITAKLESENSADRMVALANLRGVSAEEAVPLIKKVLNDKSLQVRSMAVFALGVKPTEECYPILVKLLENDPDYGIRADAAGALGYLEDIRAFDALVHAFYEDTEWLVRFSAAVSLGNLKDPRARDVLLKALESEQVVIQQAAISALGEIKAIEAIDRILNFAQSEDWLIRQRLAEALGNLPSAKSISALKYLEKDSNSQVSEAATFSLDRLSKTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1Z9</accession>
    <name>A0A2G4F1Z9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_009035</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000041">
        <property type="protein sequence ID" value="PHX55772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55772">
        <property type="protein sequence ID" value="PHX55772"/>
        <property type="gene ID" value="CP500_009035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="PTHR43398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="7">
        <location>
            <begin position="41"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="8">
        <location>
            <begin position="278"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="405" mass="45514" checksum="099D3AC061CD7EF4" modified="2018-01-31" version="1">MGLNQPNHLVPVPSNPLQISAGPTVTSTSATDAAEPQIYFSLIIPTYNECKNVKTIIEKLSQLLDGSIPGDYELIVVDDDSPDRTWELALSLTPDYPQLRVMRREHERGLSTAVIRGWQVARGEVLGVIDADLQHPPETLLQLLAEIKRGADLAAASRHVAEGGVSDWSFVRRFLSRGAQTVGLVILPGVVGRVSDPMSGYFMVRRSCIAGKTLNPAGYKILIEVLGRGDIRWIGEVGYVFQERQEGESKVTWKQYIEYLRHLLILRLARWPMGKFLRFGVVGFSGVFVNMGVLYVLRHSLNLELTRSLIIAAELAIISNFLWNDLWTFGDISKRQPGNRQRLKRLLKFNVICLMGLIVNVLLVNLLFNVFGMNEYLANLIAIAAVTMWNFWINTKLSWRVTEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F220</accession>
    <name>A0A2G4F220_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_008895</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55796">
        <property type="protein sequence ID" value="PHX55796"/>
        <property type="gene ID" value="CP500_008895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="560"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="804"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="838" mass="93564" checksum="689146DA501EDF67" modified="2018-01-31" version="1">MTMQNSANQACAMSVQPPKPRKKLHELWQNIGITARSRWQQLHTLWEHRRHRRHLLTLLILGSTVLVSSTTACISYFVVRGLILDNLKQIALLKLEKGSDEIDNWLSSRKAEIETVAYSPTIRTLNWQLAEPILQGETYRLKEYFVLSLVQADGSVQNTLGTTTNSKDRKHFQKAMDGKVNVSDPLIGRSTKLSTIIIAAPIWAMPPTSNKAIGVIAGSIKVDRVASVAKSLYYGSESYAFALNSEGLPIVHPNNNLTGNIDRPAPSFLNSPDPALAAIARKMTDRQTNIELVKIEDKWVYVAYAPLEEVNWSMALVIPRDNIESQLEALNLLTFVACGLLGSAMVAAIWVIYSSESNRVQAQREAMLNRITGRIRTSLELDHIVQSTVEEIVSLLHLEQAAFGWYDSQQQMLQIMWECSKSEEAQPVKPFAPYCVNNLSLPLEQGEPIILDSDSWLEEKNLPLQLKANSYLAVPVLTQNQSHGYLICIHASHWFWSKGEVQLLKAVADQLAIAITQSHLYSQTQDQIKLLNSTLTELKKTQTHLVQSEKMSSLGQMVAGIAHEINNPVNFIFANLPYTTKYSKDLLALVSLYKQAFPEIPPEIEDFATEIELDFIEEDLPQMLGSMKMGTERIRNIVLSLRNFSRLDESEKKQADIHEGIDNTLLLLSNRIKNVIYVVKRYGDLPLVECYPSQLNQVFMNLLSNAIDALMESDRSDKIITISTALFREKSAKFIKVAIADNGNGIPDSIKDQIFNPFFTTKPVGKGTGLGLAISYKIVVDGHGGSINISKPSGGGTEFSVQIPFNKGKKEEGPSTLRLRSGRRSAQGTLQKEGRTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F247</accession>
    <name>A0A2G4F247_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_008640</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55815">
        <property type="protein sequence ID" value="PHX55815"/>
        <property type="gene ID" value="CP500_008640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="20"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX55815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="263" mass="29921" checksum="822406F130267060" modified="2018-01-31" version="1">MRSSQRLVYGRRIAHLFDLLRELVDRDMKLLYKRSTLGIAWTLINPLLQLAVFSFVFKTVIPVNVPQFSSFAFSGLLIWTWTQTALFQATGLITSNRALIRQPNFPIAILPVVTTTTGLIHFLLALPVLIIFLAIDGIQPNAVLLYMPVLMVIQFFLTVSFAYPLAAMNVTFRDTQHTLGVVLQMLFYLTPIFYNLDSIPKDFLPLYQLNPMVPLIEAYRAILLKGTHPDWQSLLIVSLIVAVLLPIGLGIFRRQSDRFVEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2B0</accession>
    <name>A0A2G4F2B0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55875">
        <property type="protein sequence ID" value="PHX55875"/>
        <property type="gene ID" value="CP500_008480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="293" mass="30913" checksum="E69E723EE640AABD" modified="2018-01-31" version="1">MVNASAQSQDDSILLAHAKADAFLREVTEQIDLDTFNPDDSEVLKRLVECMGDTRGMTRLRFAETLAEIGEVATPFLLDGLANHANPVVRRAAAKTLTLIADPTAVPHLIHALLNDQDTVVKGSSIGALARIGEPSVQALLDILASKDLPESTIGHAAWALAFIGAGAKEYLYQAIASDSSVVRGAVVGAIAKVAQEEPKPELFEILVKSLTDVDVDVRCEAAAALGNLAYKPAIPNLIELLDGGDGETRRAAALSLMKVGDRSAIEPLQAALAKESEVAIQGVIKLAISQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2B9</accession>
    <name>A0A2G4F2B9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_009805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000046">
        <property type="protein sequence ID" value="PHX55617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55617">
        <property type="protein sequence ID" value="PHX55617"/>
        <property type="gene ID" value="CP500_009805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="159" mass="18307" checksum="5FDFE85D7220ED33" modified="2018-01-31" version="1">MTLTETSNIRKLLCDPDLGLIPHLEKCLKDLHSSAIATGEKFKLEAYDIELSNCHTHKLPNDQKPLVTQLVLMKFPLTGKVQDKMELFLLVAELQNQIDIKIIDWSALERRQYDIHGIPLKQPITKVDGEMNYNLVFDKPNYCCVTLCRQFELTYAANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2G6</accession>
    <name>A0A2G4F2G6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Insulinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55938">
        <property type="protein sequence ID" value="PHX55938"/>
        <property type="gene ID" value="CP500_008175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="1">
        <location>
            <begin position="16"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="2">
        <location>
            <begin position="168"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="422" mass="46427" checksum="1072C69DBB501BA1" modified="2018-01-31" version="1">MKNEIHRTVLDNGIVVLAAENPAADIIAARIFLRAGSRCVQPEQAGLCHLLSAVMTKGTDRLSSLEIAERVESVGARLGTDATSDYFLVSLKTVSADFTDILELASELMRSPTFPEAEVELERRIALSAIRSQKEQPFSIAFEQLRQTMYQDHPYAFSTLGTEDTMSKLTRTELEQFHKTYFRPDNVVISVAGRISTEDAIALVDRIFGDWKAPATPLPTLTLPPIIANPESALKPQETQQSVVMLGYLAPAVKEAGYAPLKLLNTYLGNGLSSRLFVELREKRGLAYDVSSLYATRLDAAQFVVYMGTAPENTQTAFDGLRTEVDRLTSLQLSDEELQACKNKILGQYALGKQTNSQIAQVVGWYETLGLGIKFDEEFQAEIAQVTAAEARDAARKFFVEPYVSLVGPEAAIREFGLAAVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2J7</accession>
    <name>A0A2G4F2J7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannose-6-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55980">
        <property type="protein sequence ID" value="PHX55980"/>
        <property type="gene ID" value="CP500_007775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005976">
        <property type="term" value="P:polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001538">
        <property type="entry name" value="Man6P_isomerase-2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01050">
        <property type="entry name" value="MannoseP_isomer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MannoseP_isomer" evidence="1">
        <location>
            <begin position="25"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="15729" checksum="B74001D1490BB682" modified="2018-01-31" version="1">MAQTQELSQTLTLLASAAPNGITATELRPWGSFTTLEEGPGYKIKRIEVKPGHRLSLQMHHHRSEHWIVVCGTAKVTCGETEQVLFTNQSTYVPQCINHRLENPGVIPLILIEVQNGEYLGEDDIVRFQDDYARTESKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2L4</accession>
    <name>A0A2G4F2L4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Addiction module antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55988">
        <property type="protein sequence ID" value="PHX55988"/>
        <property type="gene ID" value="CP500_007820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="124" mass="14213" checksum="F140B9D94E5D5847" modified="2018-01-31" version="1">MTIDPQPIAIELTPRFQRDLRILGKRDRNIRKDIQPVIAQLQAGELPGDRIPGMEYEIFKVRIKNSDIQKGKSAGYRAIYYLKTSDSIVLVTIYSKSDLSDIAAETVREILGQYEQQFPESEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Z2</accession>
    <name>A0A2G4F2Z2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000030">
        <property type="protein sequence ID" value="PHX56131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56131">
        <property type="protein sequence ID" value="PHX56131"/>
        <property type="gene ID" value="CP500_007010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="350" mass="39400" checksum="7D29D2B70552DB6A" modified="2018-01-31" version="1">MFLPEVSVVVPIYNGEVDLPELIECLRSQTYPSHSVEYLLVDNNSGDRTSSILETTAFNPPSVPPLVRGGGNLDKPPLVRGGGNLERITIRHLTENQIQSSYAARNKGIHSSKGEIIAFTDADCRPESDWLENLVKPFVDLEVGISAGEIVALPGKTILEQHATRQNTLSQKHTLAHPFCAYGQTANLAVRKKVLAEVGLFRPYLTSGGDADLCWRILRETSYKLDFVESAIVRHRHRYTIKQLQSQWYRYGESNKYLHEIHGVDLMRELTTQEYCYRLARWLFKELPVVVVKSALALAKRSEGKPSKRIASSNLVELLNTPIGLVNVRSRAIGQRQAKLPQSAWEIERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F347</accession>
    <name>A0A2G4F347_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine protease</fullName>
            <ecNumber evidence="3">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_006645</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="3"/>
    <dbReference type="EMBL" id="NXIB02000028">
        <property type="protein sequence ID" value="PHX56182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56182">
        <property type="protein sequence ID" value="PHX56182"/>
        <property type="gene ID" value="CP500_006645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16383">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008629">
        <property type="entry name" value="GUN4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037215">
        <property type="entry name" value="GUN4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008256">
        <property type="entry name" value="Peptidase_S1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34800">
        <property type="entry name" value="PTHR34800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05419">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00839">
        <property type="entry name" value="V8PROTEASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140869">
        <property type="entry name" value="SSF140869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013427622" description="Serine protease" evidence="3">
        <location>
            <begin position="22"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="GUN4" evidence="4">
        <location>
            <begin position="255"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="401" mass="43644" checksum="182785D774DF7111" modified="2018-01-31" version="1">MKSRSCWLIFFLIGLSLTSCGQQKSSQEIAETVKNSIVLISYQNEGGHGTGFIVPGPTGVCTVLTARHVVEGRSLNLQTNDQKLWKTDSIQASPNLDLAVVTFPSVGEKCPYPSLNLGDSDSVKQTDQIYISGFPDRAGGGKLVRQFVRGSVSGLDVLEQGYGISYDASTFGGMSGGPVLDASGKVIAVHGKTDAQIVADLQSQQASLSEQQKATLQQAAARVAGGGVQVNTFRWGIPIKTYQANLSWESQPLAKADYTKLEQLLAAGEWKEADGETNAKMLEVAGRQKEGWLDTESIEKFSCPDLRAMDRLWVKYSDGRFGFSVQKQIYQSLGGTKDYNEKVWVAFNETIGWKGKGGKWISADELTYNTNAPSAHLPRPSQLEGVVFWGEFFSRAETCKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F359</accession>
    <name>A0A2G4F359_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000029">
        <property type="protein sequence ID" value="PHX56178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56178">
        <property type="protein sequence ID" value="PHX56178"/>
        <property type="gene ID" value="CP500_006905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="9169" checksum="C33F69B79600E027" modified="2018-01-31" version="1">MSSTTREQLHQQIDSLPDHIVEQIASLILSITTQQKIGISEYTDWQSTQWQDFSLMQLFCEDDEIEYSLEDAEEIYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F365</accession>
    <name>A0A2G4F365_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2281 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56214">
        <property type="protein sequence ID" value="PHX56214"/>
        <property type="gene ID" value="CP500_006515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="7578" checksum="60EA48D180710CEF" modified="2018-01-31" version="1">MTTKEQILQELDQVPEPVLLKLLEFLRSLKTEEEQEKLESKAWQAYLDSERERNEVYRRLANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3B8</accession>
    <name>A0A2G4F3B8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56211">
        <property type="protein sequence ID" value="PHX56211"/>
        <property type="gene ID" value="CP500_006500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="269"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="343"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="393" mass="42048" checksum="96DD1BF2F121899E" modified="2018-01-31" version="1">MNINFSRFDTLSSVLAGTTVAALTIIIGQPAIAKTPQQVANIAGPLTVQINSAIGDGSGVIIAKNGKTYTVLTVNHVVEKPDIKYTVRTSIGKNYQATSVTRLQTAPTDPDLAVVKFESTEEYPVATIADSDQAVIGTQIFVYGYPATGGLFGSEREPELSPGLVTSRPRNRPEGYTLRYQAVTWSGMSGGPVFDSEGRVIGLHGQGEFGFAQTSSGEVAPIKTGFNAAVPINTFIAKLVLAGINKSELKVDNTPAIPGPVSTTIPQNAQAFYFRGLSRLDQGDAWEAIADFNKALASKPNYTSELYFNIGNARTLISSIDPTRGPSAIQAYTRAIEANPGFADAYYNRALAHLENKDKAQAIVDFQKAAELYKQGGRTSAYQDALNRIKTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3C9</accession>
    <name>A0A2G4F3C9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DedA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_006560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56221">
        <property type="protein sequence ID" value="PHX56221"/>
        <property type="gene ID" value="CP500_006560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="204" mass="22695" checksum="E2C0C2899502F00B" modified="2018-01-31" version="1">MVEWITNTMQSMSYLGIALLMFLENLFPPIPSELIMPLAGFTASKSNEMQLAPAIAAGVIGTVLGALPWYYAGKLLSEERLKHLADKYGKWITVSGADIDKANRWFNRHGNKAVFLCRLVPGVRTLISLPAGINNMPLIPFLAYSTGGTILWVSFLTFAGYQLGKLGKDYALVDEYLAPVSKIVVVIIVIWFILWIIKKNMQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3M9</accession>
    <name>A0A2G4F3M9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uma2 family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_005755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56348">
        <property type="protein sequence ID" value="PHX56348"/>
        <property type="gene ID" value="CP500_005755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="189" mass="21663" checksum="F17207E11D45DDC7" modified="2018-01-31" version="1">MVMLIQSPSKISLEEFLLLPETKPASEYVDGEIYQKDMPQGKHSTLQFEFPSVINRVGKPQKLAYAFPELRCTFDGRSIVPDIAVFEWLQIPLNSQGEIENRFEIPPDWIIEILSPDQSSTRVINKILFCFKNKTKLGWLIDPEERLVIVFKPQQEPEIKENEDILPVLDVLSGLQLSAANLFELLSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3R5</accession>
    <name>A0A2G4F3R5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Threonine synthase</fullName>
            <ecNumber evidence="6 10">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_005900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>H2O + O-phospho-L-homoserine = L-threonine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.2.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="6 10"/>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56375">
        <property type="protein sequence ID" value="PHX56375"/>
        <property type="gene ID" value="CP500_005900"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026260">
        <property type="entry name" value="Thr_Synthase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038945">
        <property type="entry name" value="Thr_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 10 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="13">
        <location>
            <begin position="46"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="11">
        <location>
            <begin position="211"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX56375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="374" mass="39092" checksum="0A4C439EF7670272" modified="2018-01-31" version="1">MTLILPVTDSAHNSAARAAKPKHYGWPGLIEAYRPYLPVTATTPVVTLQEGNTPLIPAPAIAALIGRDVRVLVKYDGLNPTGSFKDRGMTMAISKAKEAGAEAVICASTGNTSAAAAAYARRGGMRAFVLIPEGYVALGKLAQALLYGAEVISIQGNFDRALEIVREMAVNYPVTLVNSVNPYRLEGQKTGAFEVVDALGDAPDWLCIPVGNAGNITAYWMGFCQYHQAKKCSRLPKMMGFQAAGAAPLVTGKPVSHPETLATAIRIGNPASWTQAVAASEASRGSFSAVTDEEILDAYRLLASQEGIFCEPASAASVAGLLKVKDQVPTGATVVCVLTGNGLKDPDTAINHSNNQFKSGIAPTLDAVAGAMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3U2</accession>
    <name>A0A2G4F3U2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 16">Homoserine dehydrogenase</fullName>
            <ecNumber evidence="6 16">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CP500_005340</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH</text>
            <dbReference type="Rhea" id="RHEA:15757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 16">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="6 16"/>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56430">
        <property type="protein sequence ID" value="PHX56430"/>
        <property type="gene ID" value="CP500_005340"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016204">
        <property type="entry name" value="HDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000098">
        <property type="entry name" value="Homoser_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9 16" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="11 15 16" id="KW-0521">NADP</keyword>
    <keyword evidence="12 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 16" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="18">
        <location>
            <begin position="356"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000098-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000098-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="PHX56430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="432" mass="46129" checksum="1EF3EA81303527F4" modified="2018-01-31" version="1">MAFKIGLLGLGTVGAGTAEILLSPDGRHPLLQELEIYRVGVRDISRTRSLQLPENVLTTDLEAIATDPQVDIVVELIGGLEPARSLILQAIASGKHVVTANKAVISRYGQEIFEAANEKGVYVMSEAAVGGGIPVIQTLKQSLGANRIQTVIGIVNGTTNYILTRMQTEGADFAEVLADAQQLGYAEADPTADVDGLDAADKIAILASLAFGGRINLKDVYCEGIRQVSAADIDYADKLGFVIKLLAIAQDIKSKPDTEMLSIRVHPTFVPKTHPLASVNGVYNAILVEGEPIGQLMLYGRGAGAGPTASAVVSDMMNIAAILKTETVPIPHPLLSCTHQHYCKIAPMQELVTRFYARFLTLDHPGVIGKLGTCFGEHKVSLESVVQTGIHGDLAEIVVVTHDVREGNFQQAIDEIRAMESIDSIASILRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3W2</accession>
    <name>A0A2G4F3W2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system HicB family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56450">
        <property type="protein sequence ID" value="PHX56450"/>
        <property type="gene ID" value="CP500_005460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="7000" checksum="367FF4FD0E4370CB" modified="2018-01-31" version="1">MSRYSIIVQWSDEDRLFLVTIPEFGDRVVMPCTHGQTRSEAIDNGEEVIEMYTDSSLSGTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F401</accession>
    <name>A0A2G4F401_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56513">
        <property type="protein sequence ID" value="PHX56513"/>
        <property type="gene ID" value="CP500_004985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="9"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="143" mass="16250" checksum="BD2F34CA65ADF68F" modified="2018-01-31" version="1">MSTTIDNFTKQLHDNLEAIEDRAKLLKESVQSATKNTEAELQSKLDEMKTNLEAKKQQFDEYREKLKTQFEEKESEVKSNVEEWKASREVKKLEHRADQAEDYANTAILFAMATMEEAEAATLKAICTRLDATTAAAATTTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F440</accession>
    <name>A0A2G4F440_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56530">
        <property type="protein sequence ID" value="PHX56530"/>
        <property type="gene ID" value="CP500_004990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="179" mass="18419" checksum="CEDF77A9E5A31C3F" modified="2018-01-31" version="1">MSYTHTIVGHFPSHSEAEKVVLELQKKGFDMQKLSIIGKDYHTTEHVRGFLTWKDTAKAGAAGGGYWGSFVGGLFGILAGAGVLFIPGMGPIVVAGPIAGVLAGWLEGTVIGGAGAAAVGGLAGALGGLGIPKDEVVKYDTKIEAGEFIILVTGSSEDVSQAKQMLDRISQEMSMSIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Q2</accession>
    <name>A0A2G4F4Q2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56705">
        <property type="protein sequence ID" value="PHX56705"/>
        <property type="gene ID" value="CP500_004140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="349"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="666" mass="74682" checksum="99C3CED24DB87762" modified="2018-01-31" version="1">MKSIMLSEQPVILEKPAVWSRLFLWMIMLMTTSAVVWAYFASIEQAVPAVGQLELKDGARDIQAPATGAVVRVHVENGDRVEKNQPLLTFNPVASSADFTSIKKTKEALEKENKFYEDVVNGKIQGAIPSNLESTIKDRQSLTAQNQVLQALIDELYLNRGASGNFDATQQGLYVNYKSEFESRVAAAQGQVQELEKQFQQAQDAEKAAAAQMIVAQQQFGFAQNQLNYSQQQLASSQEQIKSAVAQKQLADEQLGKSQQVLKSNQGILSRLTPLVEAGAIAELQKERQEQDVFRGQSEVLKQQDQIKQREGEINSRKGEINTRLGEINTRRGEINARQGDIQKITAEVQRQQGEQGRIQESIKRAQEQLKNTKDAWAKELYSKIAENQKQIASSDSQLSRFKVENLKKLSEINGQLQKAQETRDTQVLKSPVSGVIFDLKPSKKENAKLDIAKDPICQSVIKSVVKPGEPRPARCEEAYYEAQQTEKLLKVLDDENGLQAIVYLENSNVALILEALKQKRSKLEQYHGKQLDGEKIHCEKGKSCVCPEKEVNREKLGLTKYQCVPVEVNVEAFPAMEFGTAQGEVIEISSDALAPTELRKYYAFKTTIKLKNQKFVLNKDKPNQLEVNLQSGMSVSSNINIGKRTVLQMFINRFTGKLDTFKSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4R2</accession>
    <name>A0A2G4F4R2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CP500_003625</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56715">
        <property type="protein sequence ID" value="PHX56715"/>
        <property type="gene ID" value="CP500_003625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007892">
        <property type="entry name" value="CHASE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05228">
        <property type="entry name" value="CHASE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="298"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="356"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="429"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="480"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="621"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="463"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX56715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="847" mass="93382" checksum="441B9967F688D3B4" modified="2018-01-31" version="1">MKLRRKTLSIVGITIAGLTGILYATSSSILLGSLVKAEEQEATQVVKGVLNVFTQTAEDFNSRFADWSAWDDTYAFIQNRNQEFIASNLVPEGLANLRVNIAVLVNTSGKIVYGTGLDTKKLQLKPVPEALKQRISVNDPLLQHPNADSSLAGIMLLSSGPVLISARPIVTTKSTGPIRGTLVFGRNLDAAGIAKLSKTTRLPLIVHSINDPHLPVDFQKVREKLSAKKPILVRVLSENSIAGYALVNDIYNQPALLLRVDIPRETYRQGQTSLLYLLVSVALAGIGFIGCTLLLLEYLVLSRLSDLAKGVNRVSASQDLSVRLPVTGEDELSDLANNINGMLSAIAIAENEQIEEKARYRAVVEQATDCIFLWDAKTQCLLEANTAFINLLGYSPDAILQLTIYDIVAYSKELIDTNIELLLADKQFKIGELLYRRRDGSYVDVEVSGSVISYGGREIICTVVRDITERKQAEAELRASEERYRLLFKNNPHPMWVYDLKTLQFIAVNQAAIQHYGYTPDEFLAMTIVEILALENSPRLLKNISQIDAPIDLTKVCQHQKKNGEIIDVEINSYELVFDNVKAELVLAHDVTARLQAEAELYKAKEAAEAANLAKSQFLANMSHELRTPLNAIIGYSEILQEDALDLGEDEFVIDLEKIHNAGDHLLGLINDILDLSKIEAGRMELILETFDLLAAIQKVKTTVYPLCLRNTNRLNIECIANIGSIKSDQTKLIQILLNLLSNASKFTQNGTVTLSVERIKNDENSWDDDCLIFKCTDTGIGMTAEQVKKLFQPFTQADASTTRKYGGTGLGLAIAQKYAEMLGGEITVESELGKGSIFTLMLPGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4V0</accession>
    <name>A0A2G4F4V0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56776">
        <property type="protein sequence ID" value="PHX56776"/>
        <property type="gene ID" value="CP500_003980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11269" checksum="D30651ED313E8087" modified="2018-01-31" version="1">MLSQVHSQPTKSDRTVAPTKILESRIQYKSCRIRVPDLTQPVAAILVDREYYSFFKALKEPEKVLATVAKLGNRGDSTAITKTASGYAIWVMEPEADAVSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4Z5</accession>
    <name>A0A2G4F4Z5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)H-quinone oxidoreductase subunit 1</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NAD(P)H dehydrogenase I subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ndhA</name>
        <name evidence="7" type="ORF">CP500_003445</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:42608"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:42612"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of at least 11 different subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cellular thylakoid membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the complex I subunit 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56795">
        <property type="protein sequence ID" value="PHX56795"/>
        <property type="gene ID" value="CP500_003445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01350">
        <property type="entry name" value="NDH1_NuoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018086">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11432">
        <property type="entry name" value="PTHR11432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00667">
        <property type="entry name" value="COMPLEX1_ND1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00668">
        <property type="entry name" value="COMPLEX1_ND1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0618">Plastoquinone</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="300"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="372" mass="40351" checksum="7FCFE19D673CB841" modified="2018-01-31" version="1">MNPGIDLQGSFVEALMNLGLPADIAQVLWLPLPMVLMVVGAVFGVLTSVWLERKISAAAQQRIGPEFLGPLGVLAPVADGLKLVFKEDIVPAKADPLLFTLGPVIVVIPVFLSYLIVPFGEHMLIADMGTAIFLWIALSSIQPIGLLMSGYASNNKYALLGGLRAAAQSLSYEIPLALAVLAVVMMSNSLSTIDIVHQQAGYGIVGWNVWRQPAGFLIFWIAALAECERLPFDLPEAEEELVAGYQTEYTGMKFALYYIASYVNLVLSCLLVAVLYLGGWECPIPVGVLTNALGLSETTPWLQVITGTLGITMTLLKAYFFLFLAVLLRWTLPRVRIDQLLNLGWKFLLPVALVNLLLTAALKLAFPFAFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F523</accession>
    <name>A0A2G4F523_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56825">
        <property type="protein sequence ID" value="PHX56825"/>
        <property type="gene ID" value="CP500_003240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="13957" checksum="FD82DE8CB33C9C2F" modified="2018-01-31" version="1">MSQIRLYLDEDSRSKKLLQALQSRGVDVITVAETGMLSRSDEEQLIWAFTNQRVIYSFNIRDFYRIHTNWLERGDSHAGIILGQQNYSVGEQMRRLLSLISAKSAAGMQNQIEFISAWSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F543</accession>
    <name>A0A2G4F543_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplL</name>
        <name evidence="4" type="synonym">rpl12</name>
        <name evidence="7" type="ORF">CP500_002995</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56892">
        <property type="protein sequence ID" value="PHX56892"/>
        <property type="gene ID" value="CP500_002995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="5"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="62"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="129" mass="13596" checksum="1D61D94BB370830C" modified="2018-01-31" version="1">MSTATDEILEKLKSLTLLEASELVKQIEEAFGVSAAAPVGGMMMMGGPAAAAAEPEEEQTEFTVVLEEFPSDKKIAVLKEVRAITGLGLKEAKELVEAAPKAVKEAIAKDAAEEIKKQLEAVGAKISIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F567</accession>
    <name>A0A2G4F567_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2786 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000009">
        <property type="protein sequence ID" value="PHX56900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56900">
        <property type="protein sequence ID" value="PHX56900"/>
        <property type="gene ID" value="CP500_002670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024498">
        <property type="entry name" value="DUF2786"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10979">
        <property type="entry name" value="DUF2786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2786" evidence="1">
        <location>
            <begin position="6"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="26061" checksum="2795474143A137B9" modified="2018-01-31" version="1">MADTNIVDKIKKLLALATSSNENESTAAAEKASLLLAQYNLSLADLGPNQQEEISESGVETTPRYVTWKMILLSGIAEANGCNAMRNTYTGTMFLVGTSTNLTVCTHLYEYLSHAIERRAKYRKGSGRGLAYLNAFRVGCATKLRQRLLEQKSEMEESGIPGVGDVAATPAIVVRSMFEKNQQAIAKYLETLGGKVKKRTGSQISSEAGFNTGYEVGDQISLHKQVKPQGDMKQLNESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5D1</accession>
    <name>A0A2G4F5D1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56956">
        <property type="protein sequence ID" value="PHX56956"/>
        <property type="gene ID" value="CP500_002385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="195" mass="21412" checksum="DFC6279650446DC3" modified="2018-01-31" version="1">MAEKIPENPEFEPLTRTQVLVAMGVTAIILLVIAKLWLQFGSVSLLPIKLIGIDLLKGCAIGLAITGASAIVYHLWPAYRRSADVYLEVVLKPLFWPDLIWLGLLPGLSEELLFRGVMMSALGLNATGLILSSFCFGILHLGGIDQWPYAVWATAVGFLLAYSFLDTGNLLVPIVAHICTNLISSCVWKWENARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5G2</accession>
    <name>A0A2G4F5G2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57012">
        <property type="protein sequence ID" value="PHX57012"/>
        <property type="gene ID" value="CP500_002140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013828114" evidence="2">
        <location>
            <begin position="29"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="159" mass="16662" checksum="83B823F81DD30E92" modified="2018-01-31" version="1">MKSLKSNLIVLGSVGLLFLGACSKGDQASDPNSSPASPPVASQPASSAPATAPATATKGGQVVKSGAYYLEFVPEKEATGTHLDLFLQKGEKKEPVPNAKMTAQVQLPNGKQQTLALKYDAEGKHYAVLFPGNEPGQYPVKVTADINGEKVDGRFTFSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5I2</accession>
    <name>A0A2G4F5I2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_002195</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Carboxysome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57020">
        <property type="protein sequence ID" value="PHX57020"/>
        <property type="gene ID" value="CP500_002195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031470">
        <property type="term" value="C:carboxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044870">
        <property type="entry name" value="BMC_CP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51931">
        <property type="entry name" value="BMC_CP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="1" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC circularly permuted" evidence="4">
        <location>
            <begin position="4"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="BMC circularly permuted" evidence="4">
        <location>
            <begin position="107"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="214" mass="23017" checksum="A4D88662020C51F7" modified="2018-01-31" version="1">MGIELRSYVFLDNLQPQHAAYIGTIAAGFLPLPGDASLWIEISPGIEINRITDVALKSASVRPGVQIVERLYGLLEVHSGQQGETRAAGKAILEFMGVRREECIKPRVISSQIIRNIDPHQTQLINRTRRGQLLLAGQTLYVLEVEPAAYAALAANEAEKGASINILEVQAVGSFGRLYLGGAERDIIAGSQAAIAAIEGVAGRENPVILGRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Q6</accession>
    <name>A0A2G4F5Q6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_001965</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MlaE permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57068">
        <property type="protein sequence ID" value="PHX57068"/>
        <property type="gene ID" value="CP500_001965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="270" mass="29439" checksum="DF08D417FD19815F" modified="2018-01-31" version="1">MVKKYQKKCDRHLDETFNNRWFQRFSVTLFLGGQVLWRIIQGKIDRRKIMEHLVTVGLDSLRAVLLIAFFAGMIFTIQSARELIRFGAVGAVGGAFALAFCRELAPVLTAGVVAGQVGSAFAAEIGEMQVTEQIDALYMLRTNPVDYLVVPRVIACCVMLPILTIFSVAVGIVGGVFVAAVFYELEPSVFLESVRTFLGPWDLVTVAIKSFIFGWIIAIVGCGWGLTTTGGGKGVGQAATAAVVTSWVFIFVADFFLSLLLFHELGITRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5U7</accession>
    <name>A0A2G4F5U7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57128">
        <property type="protein sequence ID" value="PHX57128"/>
        <property type="gene ID" value="CP500_001640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1008"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="960"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1031" mass="115264" checksum="6DC3B6BD698F9A2F" modified="2018-01-31" version="1">MYQNLPITSQLYNISLWLAQVPAERTLNTVEDAALLYSGPQFFIALIAGVVLAFAFQLLLTNLSVAAGLSYMGNQSHESSHSHSDSPQVRHIGKKVGTWTLITVTIALFFACLLAVKLSLISSPGLGAIVGLVVWATYFSMLVWVSSTTVGQLIGSLVNTATSGFQAIFGTAAAALGAKAASNQVVATAKAAAAAVGHELGSAIDPISLRENVEDYIQGLKPPELDIKGMRSEFEKLLNDPQLKSIAGENLPSLDRQTLVELVSSRSDLSKRDVNRIVDQLQDAWKQVGKKGEQTDGIAQLVEYFKSAKSGELLSDKLTSRVEQTLSNLGGQNQGQSPTMMSQATTMAVNALMGIVLGRTDISDFDVEKVVGQLKTAKDKVSQQTDKITAQVKGEPEPYSYIRADVENYLLNAYSWQMNPEKIEHDFREVIYDPSADPGTVRRELEKLKKSKFAEILASRGVFTQSKIKEIVNELETIRQRVLNTVIFAEEQEKVRDLQWRLETYLKLTPKEELTAAAIGKDFQPILEDSDATYEQLRDRLAPYNKDSFVRILRGRESFGFQEVEEIVKDLERTKDVVLADAQGLQEAAKVRIDNQWQKVQEYLQSTGKSELNPEGIKRDFKTLLENPEAGMWALRSRASKFDRETLVKLLSQRKDLSEDQVNQLLDSAEETWHSALNAPQKIADKAKEQYDETTTALADYLRNTGKSELNPEGIQRDLTKLMENPKEGALALRGRLSHFDRDTLVKLLSQREDLSEEQVNQIIDQVQNTIGSIVKSPRRLARRMQSQAQDFQGVLEDYLRNTGKDELNPEAIKRDLQLLLHDPKVGAYSLGERLSHIDRATVVSLLSQRPDISEVEANRIVDQVLSVRDQFQQQIQKIQERIQSVIDGILAKVRDYLNSLDRPELNYEGITRDVRKLFDDPQAGFDALRDRLLHFNRDTLVALISSREDISEADANRLIDQIEKSRNTVLQRAERLQQEAQLRLESIKLQAEKQAEETRKAAEVASWWLFFTALSSAVASAGAGALAVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5U8</accession>
    <name>A0A2G4F5U8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 12" type="primary">rpsE</name>
        <name evidence="7" type="synonym">rps5</name>
        <name evidence="12" type="ORF">CP500_001735</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="function">
        <text evidence="7">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57142">
        <property type="protein sequence ID" value="PHX57142"/>
        <property type="gene ID" value="CP500_001735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="11">
        <location>
            <begin position="25"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX57142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="181" mass="19056" checksum="0EA4A3D92B42C60D" modified="2018-01-31" version="1">MAEQKEQRNKKKSSNNKGREKESEWQERVVQIRRVTKVVKGGKKLSFRAIVIIGNERGQVGVGVGKASDVIGAVKKGVADGKKHLIEVPLTKSNSIPHPINGAGGGAKVMMRPAAPGTGVIAGGAVRTVLELAGVRNILAKQLGSGNPLNNARAAVNALSTLRTLSEVAQERGIPVENLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5V8</accession>
    <name>A0A2G4F5V8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">infA</name>
        <name evidence="5" type="ORF">CP500_001715</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57138">
        <property type="protein sequence ID" value="PHX57138"/>
        <property type="gene ID" value="CP500_001715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX57138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="74" mass="8549" checksum="EB17C6B6296A33BE" modified="2018-01-31" version="1">MSKQDLIEMEGTVVDSLPNAMFRVDLDNGFNVLAHISGKIRRNYIKILPGDRVKVELTPYDLTKGRITYRLRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F635</accession>
    <name>A0A2G4F635_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase/adducin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57232">
        <property type="protein sequence ID" value="PHX57232"/>
        <property type="gene ID" value="CP500_000895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="28"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="257" mass="28892" checksum="C9EE72E0BC007D64" modified="2018-01-31" version="1">MIDIKVPKVVIKPLTFNSIEEERRHRKERLAAALRLFGKFGFSEGIAGHITVRDPELLDHFWVNSFGMHFSLIRVSDLILVNHKGEVVEGNKPVNEAAFAIHSQVHAARPDVIAAAHAHSPYGKSWSSLGRLLDPLTQDACSFYENHALFDDYTGVVLEIEEAKRIAKTLGDKKAIILQNHGLLTVGETVDEAAWWFIAMERSCQAQLMAEAAGKPISIKPECARLTQQQVGSHRMGWFSFQPLYDMIVRREPDLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F663</accession>
    <name>A0A2G4F663_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F(0) sector subunit b</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">ATPase subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-type ATPase subunit b</fullName>
            <shortName evidence="11">F-ATPase subunit b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">atpF</name>
        <name evidence="14" type="ORF">CP500_002505</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).</text>
    </comment>
    <comment type="function">
        <text evidence="10 11">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cellular thylakoid membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">Belongs to the ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56977">
        <property type="protein sequence ID" value="PHX56977"/>
        <property type="gene ID" value="CP500_002505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="SSF81573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="3 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="61"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX56977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="175" mass="19018" checksum="A8DE51A04ED8731A" modified="2018-01-31" version="1">MGTVLLLATEASREGGFGFNSDILETNLINLVIIIAVLFYFGRGFLGNILNERRTGIQEAILEAEKRQKDAAAALAEQQQKLTQAQAEAERIRTASEETAKKAKEAILAQAAQDVERMKATAGQELESERERAIAQLRSAVVSLALAKVESQLKTSLDENAQHQLIDRSIALLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F688</accession>
    <name>A0A2G4F688_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_000525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57304">
        <property type="protein sequence ID" value="PHX57304"/>
        <property type="gene ID" value="CP500_000525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="143"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="223"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="263"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="303"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="343"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="423"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="463"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="503"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="583"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="3">
        <location>
            <begin position="869"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="755"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1185" mass="132926" checksum="C0BF1E2EE03A2628" modified="2018-01-31" version="1">MQWSMRWDMIFLAPFRGNNMAWHWRQSRQMLRRCRIKYPVLALLTIALALLATVAPARSRIAPTRVEGGVSVAVERSQFIPEKLAQQQEATPSQSDRAAAQRAFDEALQLSQQGTTESLRQAIQKNEEALGIWRKIGDRYQESATLNNIGNTYNSLGDKQKALDYYNQALSLSRTFGEPLNEAHTLYNIGEVYGNQGERQKALDYYNQALSLYRAVKDRAEEAKTLNKVGLVYYNSGEYQKAIDYLNQGLAIYKTIENTTGIADTVGNLGSIYLELNEYQKVIGFYNQALSIYQATGNRAGEGRMLINMGVVYINLRETQKALERLTQALKIWQELKDRRGEAFALGNIGNVYKNLSEYEQALNYYNQAISIFQAIGERDQEAYSLNQIALTYQDMGEMQKSLEVYKQSLAILKSIGNRAREGVTLNNIGNTYTNIGEYQKALDAFTQALLVFRDIKNPWLEAKARSNIGGIYQILGETQNALDNYNQALSLHQTVGDQEGEAIVLNNIGVIYNISGDQQKAIEYYNQALPLHRSVGNRYQEALTLSNIGKAYDDLGEFQKALDRQNQALSIWKAIGARYGEASSLNNIGAVYRSLGEPQKALEYYNQALVLRRATSDRYGEAFTLKNIAGVEAALGNLNQALTQIEVAIAIIEKLRTNIVSSDLRTSYFASVQATYGLNIDILMALHRQNPNAGHDIAAFEVSERARARSLIELLNEARADIRQGVDPELRDLERQILQKLTAKIQYQDQLLKNQHTEKQAETIRKEISELETQLQQVKAQIRTASPQYAELTQPQRLNFKEIQQVVDADTILLSYWLGEERSYVWAVTPTSIAVRELPKRAEIETAAREFYNYLTVPKLRYTADAEEKAATLSKIILAPVAEQLQQKRLLIVGDGELQYIPFSALPVPMSPTTASPKLLIAEHEIVSLPSASTLSIIRQSTANRALAPKAVAVLADPVFDAQDKRVKASSNPQTSPLLTPNLTRVTESEGETWTRLAGTRKEAEIILSLVADSEEMQAFDFDANLDKAADSVLSNYRIVHFATHGFFNRKNRQISGIVLSLVNQQGASQNGYLLTPAIFNLNLPAELVVLSGCETGKGENVKGEGIIGLTRGFMYAGAKRVMVSLWSVSDEEETSELMSRFYQKMLKDGLPAARAFREAQLSMMQEGKEPYYWAPFILQGEWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6N5</accession>
    <name>A0A2G4F6N5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57453">
        <property type="protein sequence ID" value="PHX57453"/>
        <property type="gene ID" value="CP500_000290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043734">
        <property type="entry name" value="DUF5678"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001995">
        <property type="entry name" value="Peptidase_A2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18929">
        <property type="entry name" value="DUF5678"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50175">
        <property type="entry name" value="ASP_PROT_RETROV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A2" evidence="2">
        <location>
            <begin position="92"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="197" mass="22369" checksum="57108A69C00A8563" modified="2018-01-31" version="1">MLKWLNRNRQQLKQYAHQYVAYNANGIIANSENLREILHLAEASGELFSIYLVPGFTASILILPIYFRTVSTHDWSPTYQINLKHKELVMNATMIVDSGADFSIISLKAGQDLGYALADGEQILVGQTIGGTVEYVLRQIEMTIDGQTLMVPTAWIQNNIADVMLLGREVVFDKFNIEFRQADEEIIFTRREDKLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6N7</accession>
    <name>A0A2G4F6N7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57420">
        <property type="protein sequence ID" value="PHX57420"/>
        <property type="gene ID" value="CP500_000340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="178"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="331" mass="36851" checksum="669B5B3CFF4CD988" modified="2018-01-31" version="1">MAVVDQDENLILAIDHSWSDDGGLGIQGWIVGKKEGVLNEVVVGAGDTFVPISAWYPRPDVAAAYPQYNSNPNCGFIVYLPRTAKHQLTFHAKSQGVSYSKNVTFAGSKPSVYDFAAFKNDDDGIFRDFINLVNNNNLRVLEIGSRIVSPGTTSKRSLFSDGASYTGFDYYADANTDVVGDAHKLSQYFSGQKFDAIFSTSVFEHLAMPWVVAMEINKLLAVGGITFHSTHFAWPLHERPWDFWRFSDEGLKVLFSQAIGFEVIRSELYVPLRMHLDTMIQGQETLTTQPAFGGVAILAKKVAEINSEKFRWDVTLTDILTSESHYPKPNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Q6</accession>
    <name>A0A2G4F6Q6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57440">
        <property type="protein sequence ID" value="PHX57440"/>
        <property type="gene ID" value="CP500_000450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14692" checksum="0D5DA0AFF21AAB3E" modified="2018-01-31" version="1">MADDYELLNLGGLTSLITNINVSLWGNQIVFECIYDPTGHRSPYSIVFQDCRDISWEVFHPEDVKDPEADLIGFHLGEDAHRTAALIHTDIFEISILYGSFSIHKEENINSPIADLETEVLTSNTPAVLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6R6</accession>
    <name>A0A2G4F6R6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57439">
        <property type="protein sequence ID" value="PHX57439"/>
        <property type="gene ID" value="CP500_000445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="120" mass="13256" checksum="788FA9638059A479" modified="2018-01-31" version="1">MVDEETCVPSQGVGGNGIASEFGDLTGMTRQQVDDFLRGLGAEIKTTQRGYLEYEFADRSRVHIRTDGEVIRTPAPKYASDGRRLNKGLRLDRDGSLVKTLDEFGNQIPGTHNTGEKVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6T3</accession>
    <name>A0A2G4F6T3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Pyrroline-5-carboxylate reductase</fullName>
            <shortName evidence="2">P5C reductase</shortName>
            <shortName evidence="2">P5CR</shortName>
            <ecNumber evidence="2 3">1.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">PCA reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">proC</name>
        <name evidence="6" type="ORF">CP500_000405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="2 3"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57431">
        <property type="protein sequence ID" value="PHX57431"/>
        <property type="gene ID" value="CP500_000405"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="4">
        <location>
            <begin position="5"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="5">
        <location>
            <begin position="175"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX57431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="281" mass="29100" checksum="70DA472F51272E10" modified="2018-01-31" version="1">MTNIKFGTIGGGVMGEALLSRLIAQEVYLPSEILVSEPGVQRREFLTEKYGIRTTASNLEVAAATEVLFLAIKPQVFETVALELAVADDRTQGNNGETANTKSEALVVSILAGVPLSKLEAAFPGRGVVRVMPNTPATVGAGMSAIAPGKFVQPADLELVTRIFLAVGEVVEVPENMLDAVTGLSGSGPGYVAILIEALTDGGVCAGLPRAIASQLALQTVFGTAKLLQETGMHPAELKDRVTSPGGTTIAGIAKLESSGFRSALIEAVKAACLRSQELGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUI2</accession>
    <name>A0A2G4EUI2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA-binding protein hfq</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_022820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000247">
        <property type="protein sequence ID" value="PHX53191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53191">
        <property type="protein sequence ID" value="PHX53191"/>
        <property type="gene ID" value="CP500_022820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="70" mass="7918" checksum="183BD2D1E3A46D11" modified="2018-01-31" version="1">MSEFETGLPSVRLIQSYIKDKQQIELKLLTGDLLVGRVFWLDNSCICVLDASEKQILVSRQAIAYIKSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUT8</accession>
    <name>A0A2G4EUT8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="13">1.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">3-IPM-DH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Beta-IPM dehydrogenase</fullName>
            <shortName evidence="13">IMDH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">leuB</name>
        <name evidence="16" type="ORF">CP500_022275</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32271"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.85"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13 14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13 14">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 14">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="13"/>
    <dbReference type="EMBL" id="NXIB02000221">
        <property type="protein sequence ID" value="PHX53295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53295">
        <property type="protein sequence ID" value="PHX53295"/>
        <property type="gene ID" value="CP500_022275"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01033">
        <property type="entry name" value="LeuB_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004429">
        <property type="entry name" value="Isopropylmalate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979">
        <property type="entry name" value="PTHR42979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00169">
        <property type="entry name" value="leuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 14" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0520">NAD</keyword>
    <keyword evidence="10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="15">
        <location>
            <begin position="6"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="PHX53295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="359" mass="38746" checksum="2E4A708DF2034FDE" modified="2018-01-31" version="1">MTQNYRITLLPGDGIGPEIIAVAVEVLKLVGKKFDIGFEFQEALMGGAAIDKTGNPLPDETLEICRNSDAILLAAIGGYKWDNLPREQRPETGLLGLRAGLGLFANLRPATILPQLVDASSLKREVVEGVDIMVIRELTGGIYFGKPKGIFQTETGEKRGVNTMAYTESEIDRIGRVAFETARKRGKRLCSVDKANVLDVSQLWRDRIIALSSEYPDVELSHLYVDNAAMQLIRWPKQFDTIVTGNLFGDILSDAAAMLTGSIGMLPSASLGATGPGVFEPVHGSAPDIAGQDKANPIAQVLSAAMMLRYGLNQPEAANKIEQAVVEVLDRGYRTGDIMSEGMKLVGCRAMGDALIEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV13</accession>
    <name>A0A2G4EV13_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protoheme IX farnesyltransferase</fullName>
            <ecNumber evidence="8">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Heme B farnesyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ctaB</name>
        <name evidence="9" type="ORF">CP500_021825</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000206">
        <property type="protein sequence ID" value="PHX53379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53379">
        <property type="protein sequence ID" value="PHX53379"/>
        <property type="gene ID" value="CP500_021825"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX53379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="325" mass="35797" checksum="E98C0BAAF9EB0AF5" modified="2018-01-31" version="1">MQEVLTNNSPRLHENFSQVAKSYYQLTKPRIILLLLITTSAGMWMAAKGEVEPLLLVSTITGGALASASANTINCVYDSDIDYIMERTRWRPIPSGRVKKRDALIFAIALATISFTLLTVVANLLAALLAMSGIVFYVLIYTHWLKRHSVQNIVIGGAAGAIPPLVGWAAVTGDLSWGAWMLFGIIFLWTPPHFWALAMMIRDEYEGVGVPMLPVIEGDEETARQIWIYTLLMLPATLLLVYPLNLAGGVYTGTAIFLGAIFAQKAWLLLQTPEDKNLARSLFKYSILYLMLLCAGIVVDSLPATHNFTTAVVHNVHTFISAVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV29</accession>
    <name>A0A2G4EV29_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_021790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000205">
        <property type="protein sequence ID" value="PHX53385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53385">
        <property type="protein sequence ID" value="PHX53385"/>
        <property type="gene ID" value="CP500_021790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="46"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="221" mass="24872" checksum="6D25BD0613BC3ED2" modified="2018-01-31" version="1">MQRVLEPEVMDSLEEALEYDSMDFIEVNTAFARSAAVLGPVFGNVLDAGTGTARIPIALYELRPAWKLTCIDLSANMLKVAAENVEKAGVRSQISLELIDAKAMPYPDNYFDMVISNSIIHHLPDPLPFLQEVRRVLKPNGAIFLRDLLRSETLEIRDNLVELYAGDCNAHQKQLFSDSLQAAFTLDEVEEMIQNAGLDGLRIYESSDRHWTAERVWCESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV40</accession>
    <name>A0A2G4EV40_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_022250</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000220">
        <property type="protein sequence ID" value="PHX53300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53300">
        <property type="protein sequence ID" value="PHX53300"/>
        <property type="gene ID" value="CP500_022250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007890">
        <property type="entry name" value="CHASE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05226">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01080">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="406"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="479"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="569"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="514"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="700" mass="78871" checksum="143AC65E9BE44833" modified="2018-01-31" version="1">MRAILKKWLRQERRVLITATAVVGTVMLVRWFGLLQLWEWAAFDQFVRWRPAEPIDNRIVIVEIGERDLQKYGYPISDGVMAKLLQKLDAGKPRAIGLDIYRDLPTQPGNAELLKTFKTIPNLIGIELMADESRLGVRPPPVLNKLDRVGFNNVVIDADGKVRRMLLYAWPSDGKTRQSFALKLALLYLESEGVSPQPASVNPKYLQLGKGVFRPFQQNDGAYVRSDSRGYQILASLRGPVGSFRTVSISDVLSDKVPVDFVRSRIVLIGSTATSLKDSHQNAYSYDLFNSPQQISGVELQAHFLSQILSAALDGRGGINVLSDSLELLWILLWSWVGASVSWKLRSLSRSAWCLLSISIFLNATLYIAFLTGWWLPLIPPMLSLLGSGVAVVGYLAHLQEELKRSKEFLQSLIDTIADPIFVKDQNHRMVVLNETYCRFIGSSLENITSKTDYDLFPKAEADIFWEQDELVLKTNLQLEHEERFTDTHGITHLIATKRSLHKDAVGNLFLVGIIRDITERKRLEEELKQKNAELSHQADHDVLTGLPNRKFFYERLNQSLEKALINNEFLALLFLDLDGFKLINDTLGHNTGDLLLKAVSDRLKRCLRGSDTISRLGGDEFTVILPGIPGREEAAKVAEKIRDAIKEPFVLEENTVCVTTSIGISLYPVDTQDRDVLVNCADAAMYRAKEFGKNQYQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EV67</accession>
    <name>A0A2G4EV67_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000210">
        <property type="protein sequence ID" value="PHX53356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53356">
        <property type="protein sequence ID" value="PHX53356"/>
        <property type="gene ID" value="CP500_021970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="116" mass="12930" checksum="D850A72242A0AE73" modified="2018-01-31" version="1">MPKSLPYHPFLIQSLKNPIDSAMYLEAFFEEENPEAELLKMVLSNVAESLGQPKMSPEQYELHLKKLDELLSQPGSDTIYNLGTWLNALGLKLTVAICTDTEDNNVNPAIPAQLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVI4</accession>
    <name>A0A2G4EVI4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_021295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000192">
        <property type="protein sequence ID" value="PHX53476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53476">
        <property type="protein sequence ID" value="PHX53476"/>
        <property type="gene ID" value="CP500_021295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="7108" checksum="A280C60FB7DC88BF" modified="2018-01-31" version="1">MTVLVEELLNTFERLTDSERLDLVLEILKRTVDLDFLPLSDDDLVLNAEGLFLELDEEKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVI5</accession>
    <name>A0A2G4EVI5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000190">
        <property type="protein sequence ID" value="PHX53488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53488">
        <property type="protein sequence ID" value="PHX53488"/>
        <property type="gene ID" value="CP500_021210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="453" mass="48177" checksum="2998EF1A258D0642" modified="2018-01-31" version="1">MSSLKRLPTSVRYVIARLRYWMQPAVWAPLAVLCAGGFFIWEVSVNPERLSIDGEDVANSNNPTAIAGLSAEDTAIAAEIDSVPMLVNKFNRSNSEFGLLGSPVGKGLFDEMRDRKPEISQPSSASKQAPINTFLSIPNLANSAGSVAKNNPQNSSLSSSNTIATLSPSREGRLMSGNKTIGAEGSTDKATATLSEISDSANSGKQNDNPLPLSPLQAAMKKYITANATARATSTEKTTRAAKLSDRPNATAPVTNPANLLPTMTTAQAIANPVNFPTTLAPIPAPTSTIINDFQQVSNTATTLPESFTRLNSRVTVIPEINTQPVTLDLPKNPYQTNLSDSELVPKTQPAVIPIATPSPIQLIPNIGKSPFPDAMVETKIVNPQFSPSSANSQFKSVQPSQPNSSSQYNFGVVPQNTINQGLQPIQSQPFPAQRQIPGRYLGGGEINTFSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVK3</accession>
    <name>A0A2G4EVK3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_020845</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000177">
        <property type="protein sequence ID" value="PHX53564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53564">
        <property type="protein sequence ID" value="PHX53564"/>
        <property type="gene ID" value="CP500_020845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="671"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="705"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="5">
        <location>
            <begin position="830"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="768"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="124"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1015" mass="116529" checksum="483D272DE0276E4D" modified="2018-01-31" version="1" fragment="single">MQFAAGLISTKSPETGFFRKIYGENRKSQKNAVSSTPPKSPETGFFAKSTAQTPNLEKTRFLSPHSPTQRNKQMTKALPGKKGWLAQVGDFVKAIYRPTVYTADRNSETQVRNTDITIQANKEIEASRQELRIQEVKLQEFQRQANLTFQAEEGNLNRSLQSELARLNRESQTQEGLLNRQMQEQLAKINRDFQANEGKLNREHQIQLEIFRGELQKWCIEQQKELQLHLKNLDAQLAREIRIYDRQTSIEVIQEQKRQNNSPIWLVAQDIVNSNPTQNPIPLRVFLSPPSLQFDRSGDSNDTAKGFPEMEKFLGIYLQQFFEKYSAQGRPIEFLSGAWTSKFFHSQAATKTMFHGLKTEPTLILESVAEGDIFNLNFGYWGLNWATYRYKSPIPMLPWREVLFDFAKERALQWQAQRQAYIAQGNSAEKFDKVLGNEAVNSFLHNLEIIDNERMCEAMGIDPTDSPRPYSIHKKDYERFQQFIGVCHCLIAGLLADEYFFLHVSSDVRQRPLLPQLLPDLLRDMPKEEQEQLVEIVINFYEMLYNIIGESESAWIPELKLDLAEGLLDLPDKRWAATQIFESVKAWLKLRGLSVPEGNKEILDALDAALTIDDLKYAGKLNSCLVIVGKTRQFSVIESCYNRAIGRCKQENYAAAIVDFNQVLQLNPNFAKANFNRGLAYAKLEQYQAAIEDYTQYLRLDPNNADTWNNRGNAYYKLREYEQAISDYNQALNLNPNLSSVAHNRDVAQGVWDEKKWLRQQEEEKQQLQAEQERQRKLAAEQQRRAEEESKGKEFQFEIVTVNNRGQEVSRKPGKSYQKVADLGNGVNLEMVYIPGDSFQMGSSESSSEQPVHPVTVQPFYLGKYPITQAQWEAVMGNNPSNFKGAKRPVERVNWNEAVEFCRKLSEKTEKTYRLPSEAEWEYACRAGTTAPFYFGDTITPDLVNYDGNNPYGSVPQGLYRQQTTDVGSFPPNAFGLYDMHGNVWEWCSDKWHGNYSGAPTDGSSWETGTDNNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVM3</accession>
    <name>A0A2G4EVM3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Cytochrome b6-f complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">17 kDa polypeptide</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">petD</name>
        <name evidence="12" type="ORF">CP500_021025</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 9 10">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cellular thylakoid membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the cytochrome b family. PetD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000183">
        <property type="protein sequence ID" value="PHX53528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53528">
        <property type="protein sequence ID" value="PHX53528"/>
        <property type="gene ID" value="CP500_021025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045158">
        <property type="term" value="F:electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045156">
        <property type="term" value="F:electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00290">
        <property type="entry name" value="cytochrome_b_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01344">
        <property type="entry name" value="Cytb6_f_subIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005798">
        <property type="entry name" value="Cyt_b/b6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036150">
        <property type="entry name" value="Cyt_b/b6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005870">
        <property type="entry name" value="Cyt_b6/f_cplx_suIV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00032">
        <property type="entry name" value="Cytochrom_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000033">
        <property type="entry name" value="B6f_17K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81648">
        <property type="entry name" value="SSF81648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01156">
        <property type="entry name" value="cytb6/f_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51003">
        <property type="entry name" value="CYTB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9 10" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_CTER" evidence="11">
        <location>
            <begin position="65"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="160" mass="17516" checksum="04D8C1AC873FD026" modified="2018-01-31" version="1">MSILKKPDLSDPALRAKLAKGMGHNYYGEPAWPNDLLYVFPVVIMGTISLCVALAVLDPALIGEPANPFATPLEILPEWYLWPVFQLLRVLPNKLLGIACMAGVPLGLILIPFIESVNKFQNPFRRPVATTVFLLGTAITLWLGIGAVFPIDKSFTLGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW60</accession>
    <name>A0A2G4EW60_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53764">
        <property type="protein sequence ID" value="PHX53764"/>
        <property type="gene ID" value="CP500_019805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="268" mass="28716" checksum="BD27658B242A5FC3" modified="2018-01-31" version="1">MSEEQTNQPNQEPSPSVTPEIDSTPKSVISENMVAETNAVPTPKVAVKSNSKFVATSTTGSFLEKIGWLWQSIVKLVRSLLPASLSQKLSDPILNAAIAAILLVVVGSTLNILSGKPADQIAIESPTNLPDIVAPSGSESAKFNSKLPDLVAPSATKVVETIQPPPLTPEQSLIAGIQNQVAEFTDRLGGDLVKSIQANFTSSILTVKVAEDWYRLSEVEQNQLVKKMFKEANLLNFSNLEVMNLEGKLIARNPVVGSEMIILDSTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EW89</accession>
    <name>A0A2G4EW89_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_019500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53805">
        <property type="protein sequence ID" value="PHX53805"/>
        <property type="gene ID" value="CP500_019500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="Gdt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="PTHR12608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX53805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="155" mass="16707" checksum="E3D19D38257BB088" modified="2018-01-31" version="1">MKLDSVPPNLSDSEPVSPNSDLSKQLELKLTDTPEIFPKFSPESVEFSVSSNPDLSSEKKGVSQKEWAIFASTFVTIFLAEVGDKTQIAVLLIAAESHNPWIVFAGAGSALIATSLLGVLLGRWLASRIDPRTLERVAGVILLAISAILLWEVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWB9</accession>
    <name>A0A2G4EWB9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PadR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_019780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000157">
        <property type="protein sequence ID" value="PHX53756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53756">
        <property type="protein sequence ID" value="PHX53756"/>
        <property type="gene ID" value="CP500_019780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="27"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="130" mass="15375" checksum="09769C4E6F7C6259" modified="2018-01-31" version="1">MKFEHIYQFFQDPPPVYLNKELAVCYILSVLLRGDSYGTELIGQLEKEFPIYRLSDTVLYSALKFLEDEGVITGYWKKVEGRGRPRRMYQILPEWRHQSQDLAHLWHEYIAQGKGVSRNQHKELETGQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWG6</accession>
    <name>A0A2G4EWG6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Prolycopene isomerase</fullName>
            <ecNumber evidence="7">5.2.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">crtH</name>
        <name evidence="12" type="ORF">CP500_019510</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,7',9,9'-tetra-cis-lycopene = all-trans-lycopene</text>
            <dbReference type="Rhea" id="RHEA:30971"/>
            <dbReference type="ChEBI" id="CHEBI:15948"/>
            <dbReference type="ChEBI" id="CHEBI:62466"/>
            <dbReference type="EC" id="5.2.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.13" evidence="7"/>
    <dbReference type="EMBL" id="NXIB02000153">
        <property type="protein sequence ID" value="PHX53806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53806">
        <property type="protein sequence ID" value="PHX53806"/>
        <property type="gene ID" value="CP500_019510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046608">
        <property type="term" value="F:carotenoid isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014101">
        <property type="entry name" value="CrtISO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045892">
        <property type="entry name" value="CrtISO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313">
        <property type="entry name" value="PTHR46313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02730">
        <property type="entry name" value="carot_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="11">
        <location>
            <begin position="30"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX53806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="514" mass="56862" checksum="BD415C7BEE952FE5" modified="2018-01-31" version="1">MSAPTQSQLFSANSRATAQEFDVIVIGSGIGGLVTATQLAAKKAKVLVLESYLIPGGSAGYFDREGYRFDVGASMIFGFGDRGTTNLLTRALAAVNVSLETIPDPIQLHYHLPGGLDLEVPQSYDKYLQELVDRFPHEKEGLTKFYGECWKVFNCLNAMELLSLEEPGYLMRVFFQNPFACLGLVKYLPQNTGDIARRYIKDPVLLKFIDMECYYWSVVPADLTPMINAGMVFSDRHYGGINYPKGGVGQIAQKLVEGLKKCGGQIQYKAKVKKILTEKRHAVGVELATGEVYRAKRIVSNATRWDTFEKLLPASEMPASEKKWQQRYQKAPSFLSLHLGVEAGVIAPGTACHHILLEDWDKMEAAEGTILVSIPTLLDPSLAPEGFHIVHAFTSSWMEEWQGLSQQEYEEKKEEAAGRIIDRLEHIFPGLDAGLDYMEVGTARSHRRFLGRQDGTYGPIPKQKLMGLLGMPFNRTSMPGLYCVGDSTFPGQGLNAVAFSGFACAHRIAVDLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWJ8</accession>
    <name>A0A2G4EWJ8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000150">
        <property type="protein sequence ID" value="PHX53836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53836">
        <property type="protein sequence ID" value="PHX53836"/>
        <property type="gene ID" value="CP500_019360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="271"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="305"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="339"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="373"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="407"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="492" mass="53694" checksum="CD50CBF9C894CFDB" modified="2018-01-31" version="1">MNRSYSRFDSLTSILAGTVTVAGIVIFAQAPVFAKSPQEIAKLAESVTVQINGTDSRSGTGFIIAKQGTTYTVLTAKHVVPNSQVTYKIRTYTGKEHQVTRVMPLQKNDRELDLAVVTFNSTETYRVVTLGDSAQTEIGTQIFVIGYPNNKSRTQQNLEFTEGYVSSRPPTHKRGYTLRYSAVTQKGMSGGPVFDGEGRVVGIHGEGELDFSTNDTGASVESITKTGFNSAIPINTFIAKLSEAGLNRSALLVNTSTATNAPLKLNNPQDAKTYYVRGLSRFDKGDLSGAVADFNQAIQTQSDYVEAYFYRGLAYFDLRQMPKSIADYSKAIALNASYVDAYYNRGLVLSALGDKPGAIADYTQVIRLDRNFAAAYNNRGLALSDLGDQKGAIDDFNQALQINPGRANTYFNRGLALFRIKNDRSALADYTQAIQLNPNYAKAFANRGITLVRMGDRQGAIADLQQAARLFRAQGMNADAQKALDLIGQLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWL1</accession>
    <name>A0A2G4EWL1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF58 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_018915</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000141">
        <property type="protein sequence ID" value="PHX53911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53911">
        <property type="protein sequence ID" value="PHX53911"/>
        <property type="gene ID" value="CP500_018915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="3">
        <location>
            <begin position="212"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="389" mass="43374" checksum="4AE6E0F5116762C3" modified="2018-01-31" version="1">MNIGHKITDWLETRAVTPAYAGGLLVGLTVFFFGAATNTMAGWLYLLSGGSLALLGIAAFLPARSLHSLQVRRRAIEPVSVGDQITIELEIENRSHEPKTLLQVVDILPFVLGEPVVRAIEVIAAHSIYTDTYYLEVQQRGVYRWQEVRLRTAAPLGLFWCRRSHPVKAVAVVYPQVLPLSTCPLIDRIGQEDSPQLYDRSRSQNATEGLTRNLRPYRHGDPTRLIHWRTSARHGELRVRELEVAAGGQEIIIALDSGATWEPKEFERAVTVAASLYFYASKRLLNVKLWTAGTGIVSGNRVVLETLAAVNAGEDVVENTPKLPIIFLTQNSANLNALTQGSRWVLWPRTTAEIGEKMLVKNDFPGLEIRSDRPLELQLQSPLERAINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWP7</accession>
    <name>A0A2G4EWP7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid oxidation protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000137">
        <property type="protein sequence ID" value="PHX53949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53949">
        <property type="protein sequence ID" value="PHX53949"/>
        <property type="gene ID" value="CP500_018760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="138" mass="15859" checksum="AB4CEDFC6065F418" modified="2018-01-31" version="1">MSAKDTFHESVKRALQKEQWVITADPLRFKFGSVKFQVDLGSERLVAAERSGEQIAIEIKSFLNPSVITDFYAALGQFLSYRLGLASVDPNRKLYLAVPFEVYRTFFQSEFAQTAVQEYQVLLIVYNPKDEVIVQWIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWU7</accession>
    <name>A0A2G4EWU7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_018755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000137">
        <property type="protein sequence ID" value="PHX53948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53948">
        <property type="protein sequence ID" value="PHX53948"/>
        <property type="gene ID" value="CP500_018755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16382">
        <property type="entry name" value="XisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="111" mass="13240" checksum="F3ADBB6194EC778C" modified="2018-01-31" version="1">MDKLAQYRQYVQILMSRYAEDDVSDDEVEVQLILDTERDHYQWMNVGWEHLNRIYQTYIHIDIKDGKIWLQQNLTEQNPAEELVAMGVPREDIVLGLHPPYKRPYTDYGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWY1</accession>
    <name>A0A2G4EWY1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_018545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000134">
        <property type="protein sequence ID" value="PHX53976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53976">
        <property type="protein sequence ID" value="PHX53976"/>
        <property type="gene ID" value="CP500_018545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="106" mass="11665" checksum="79E02F4652785774" modified="2018-01-31" version="1">MANSRFNIQDFKHRVPIATLVILGLFGFASAISWAWLSGEGTVSGIFTQINIWQQNPPVWTQVPAISQMYLFIPTAILVSTVLATIKISPQPQKWSQAVVIAIVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWY8</accession>
    <name>A0A2G4EWY8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_020180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000163">
        <property type="protein sequence ID" value="PHX53677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53677">
        <property type="protein sequence ID" value="PHX53677"/>
        <property type="gene ID" value="CP500_020180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="159"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX53677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="357" mass="39632" checksum="6C05B212F5E50C42" modified="2018-01-31" version="1">MGAESTINQNEQLPLVVNPDILQQAILYKINTRITARGELAFPCVPGMLNYYLQSIEKLFSTLDRPLPEDRKDELRKLLATKLELGYQSSTASMLILQYESVQPPQTGLACKVIVASSTVGEQYKSWVDTREPPLFGSYPDAKLMATAAKLGSPERVRILDVGAGTGRNTLPLARLGYSVDAIELAPAFAEQLQTAVTAENLPVTVTQGDVLDPLVRMKPARYQLAVAAEVISHFRDSDEVRLFLAKMCDSLCPGGLLLFSTFLAVGDYQPDALVRQVAQLSWSTLFTRQELAVAMEGLPLVQISDELVFEYERDHLPQGAWPPTPWFSSWATGRDVFPMTNARPPMELRWILCQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX19</accession>
    <name>A0A2G4EX19_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome segregation protein SMC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_018445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000132">
        <property type="protein sequence ID" value="PHX54016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54016">
        <property type="protein sequence ID" value="PHX54016"/>
        <property type="gene ID" value="CP500_018445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="2">
        <location>
            <begin position="30"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="406" mass="46044" checksum="C472FD29C1BD2CFF" modified="2018-01-31" version="1">MQGKRFIRTLRLKNFLSYGSEGEEIELQPLNVLIGPNASGKSNLIDAVGILQSTPNDINTPFRQGGGIGEWLWKGENNSRNLPTATIEATVDYPNETIPLRYQISFTMVGQKLQIVDEAVENEERLGPSYEDVYLFYRYRNGNPVLNIRNVSAEGTGTNRGERRLSRDEINPSQSVLSQKQDKDFYPELAYLNNQFSNIRIYREWNLGRYTPPRKPQPSDLPNDFLEEDASNLAHVLNDLDYQGIKPLLIKQLQKFYEAVGDITTRLEGSTIQTFLRDKKFNRAIPATRLSDGTLRYLCLLTLLCHPSPPPLICIEEPELGLHPDILSTVAELLIAASKRTQIIVTTHSDALVSGLSEVPESVLVCEQNNTGTHLRRLEPPQLKKWLEKYTLGDLWRMGHIGGNRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EX31</accession>
    <name>A0A2G4EX31_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrH</name>
        <name evidence="8" type="ORF">CP500_018000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Allosterically activated by GTP. Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000126">
        <property type="protein sequence ID" value="PHX54094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54094">
        <property type="protein sequence ID" value="PHX54094"/>
        <property type="gene ID" value="CP500_018000"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="7"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in allosteric activation by GTP" evidence="6">
        <location>
            <begin position="19"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="11"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="134"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX54094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="242" mass="25904" checksum="C526941D2275271A" modified="2018-01-31" version="1">MGMVYQRVLLKLSGEALMGDLGYGIDPVVVSSIAQEVAQVVSEGIQLAIVVGGGNIFRGVKAASAGMDRATADYVGMIATVMNAITLQDALEQAGVPTRVQTAIAMQEVAETYIRRRAIRHLEKNRVVIFGAGSGNPFFTTDTTAALRAAEIDAEVIFKATKVDGVYDSDPHINPNARRYQTLTYGHVLNQDLRVMDSTAIALCKENNIPIMVFDLTVSGNIYRAVMGESIGTLVGGFCEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXI2</accession>
    <name>A0A2G4EXI2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">D-alanyl-D-alanine dipeptidase</fullName>
            <shortName evidence="3 4">D-Ala-D-Ala dipeptidase</shortName>
            <ecNumber evidence="3 4">3.4.13.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017185</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>D-alanyl-D-alanine + H2O = 2 D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20661"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="EC" id="3.4.13.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase M15D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.22" evidence="3 4"/>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54239">
        <property type="protein sequence ID" value="PHX54239"/>
        <property type="gene ID" value="CP500_017185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01924">
        <property type="entry name" value="A_A_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000755">
        <property type="entry name" value="A_A_dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01427">
        <property type="entry name" value="Peptidase_M15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026671">
        <property type="entry name" value="AA_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 4" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR026671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="236" mass="27190" checksum="71E4946A8E60AFC4" modified="2018-01-31" version="1">MKPYQQIPIDECGEALVPIPVEIFAFESPHPYQKLGAPYQNSKADSPYYLRQGVIDSLIVAQKQLQQDYPDWQILIFDAYRPVEVQQFMVDFTFAEIANAQGYELPVSEEKKQLILEQVYKFWAVPSLDRATPPPHSTGGALDVTLVDRQNGQIDMGSPIDEISERSYPDYFASSNEPAEQAFHRRRQILKDAMVGAGFRQHPNEWWHFSLGDQMWAWSMSQHPGDNQFVARYGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXJ2</accession>
    <name>A0A2G4EXJ2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_017135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54255">
        <property type="protein sequence ID" value="PHX54255"/>
        <property type="gene ID" value="CP500_017135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="162"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="230" mass="25741" checksum="7277C040D7F40C38" modified="2018-01-31" version="1">MSARLLLVDDEPGLREAVQAYLEDSNFVVEVASNARDGWELLQQHNPDLLISDIMMPKVDGYQFLKQVREDPRYKALPVVFLTAKGMTSDRIQGYTAGCDAYLSKPFDPDELVAIITNLLARRAAAKQMSENGENPDITALANQMTRIESLLSGRSSIVQLPSTIKIDLTPREQSVLDLVAQGLMNKEIARRLETSVRNVEKYVSRLFSKTGTNSRTELVRYALEHGLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXN8</accession>
    <name>A0A2G4EXN8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">VapC toxin family PIN domain ribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000109">
        <property type="protein sequence ID" value="PHX54304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54304">
        <property type="protein sequence ID" value="PHX54304"/>
        <property type="gene ID" value="CP500_016855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="101" mass="10980" checksum="4D509714F2C86E59" modified="2018-01-31" version="1">MTAVVADTHTIIWYLRDTARLSQAAMTALDAALAGGYSIYVSAISVVELGYLVERYRLPEEAFEQLINALSDPGTGLAIAPLDLITAQTLRQIPRDVEESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXP2</accession>
    <name>A0A2G4EXP2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000108">
        <property type="protein sequence ID" value="PHX54312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54312">
        <property type="protein sequence ID" value="PHX54312"/>
        <property type="gene ID" value="CP500_016690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017037">
        <property type="entry name" value="UCP035261"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035261">
        <property type="entry name" value="UCP035261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013599318" evidence="3">
        <location>
            <begin position="25"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="4">
        <location>
            <begin position="302"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="698" mass="75632" checksum="06481EC01CCFFDF9" modified="2018-01-31" version="1">MTKSRWLRKLLPFAVSFATTIALAGAIAPPTSAQVKSPPPQPQEVQPAQAEGFSIPIWIYPVGAMFLVLIFIPKIGWTLGLIAIGEREVGIVVKKFSSKNLPSSRLIALDGEGGLQADTLPPGWHFGYFPWQYSVRKEPVVVVPQDEIGLIIANDGATIPSDRILGKVVDCDNFQNARKFLTDGGEKGRQLAIITTGTYRINTAVFEVITSANAAAKGMQPSEFQLYKLAPDRVGIANVLDGIPIDEGEIAGPIIPGHDNFQKAQSFIKGGGRRGLQEQVILSGSWNLNPWFVQVEQVKMTEVPIGYVGVVISYVGESHKDVSGVAFTHGNLVNKGDKGVWVEPLYPGKHPINTKVMKVELVPTTDVVLNFTSRFSGEHGYDSKLSALKLLSFDGFTFELEIFQIIHVGTLDAPRVISRQGSMQNLIDQVLRPIVGNYFRNSAQEYTILDFLIARSERQAEAAEHVREALRAYDVQAVDTLIGLISPPAELMQTLTDRKIAQEQEKTYEVQRISESQRQELVRATAIANIQNQVVAAEQGVKIAQLSATAAIEHASGEAEGIRLMGQAKADAYQVGVNALGTQSYTLLQLMQAVSDGSVRVVPDVTVNGNGGSGGLLDGLMAMLLRNETSKNGDNEAQSPVINVKKSKSVVVEPVAESPVAKVHSVKSTESPNHSPVPQYGVVDKTDIDSAFDELSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXQ9</accession>
    <name>A0A2G4EXQ9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2TM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_016985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000111">
        <property type="protein sequence ID" value="PHX54266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54266">
        <property type="protein sequence ID" value="PHX54266"/>
        <property type="gene ID" value="CP500_016985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025698">
        <property type="entry name" value="2TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13239">
        <property type="entry name" value="2TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="2TM" evidence="2">
        <location>
            <begin position="71"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX54266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="165" mass="18810" checksum="28D2E08EB14CECC7" modified="2018-01-31" version="1">MATNESQISQVYGSEDAQAILQLAIAQKEENGELSRVQLFEIAAELGISEQDIAAAEQQWLANRGEFSEKLSFNTYRRRKLQKNLTKYGIINGFLVLLNLAGSHELSWSLFILLTWGLGLSLNAWNVYQTEGEDYEQAFQRWRLKKQVGESIGTATDKFMKWLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXS4</accession>
    <name>A0A2G4EXS4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000112">
        <property type="protein sequence ID" value="PHX54250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54250">
        <property type="protein sequence ID" value="PHX54250"/>
        <property type="gene ID" value="CP500_017090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027392">
        <property type="entry name" value="TF_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13453">
        <property type="entry name" value="zf-TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-TFIIB" evidence="1">
        <location>
            <begin position="3"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="zf-TFIIB" evidence="1">
        <location>
            <begin position="76"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="193" mass="22334" checksum="FFD76FD74A569169" modified="2018-01-31" version="1">MECPKCKHPNLEGGTLAGSMLVRWCPNCYGIWIPGREYETWQKNQRQWSLKSDKRKPGAISIEFTPSPYDSKAALCPEDGHYLSRAKVPFSRVPFYIERCKLCGGIWLDNGEWDILESLGFHMEIDQMFSPNWQFKARLQELVERERQVLIEKLGPDVAGYVMELAEVLADHPHADCAATYILRKAELKRREM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY05</accession>
    <name>A0A2G4EY05_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AbrB/MazE/SpoVT family DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_016285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54401">
        <property type="protein sequence ID" value="PHX54401"/>
        <property type="gene ID" value="CP500_016285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="82" mass="9181" checksum="BEBC333BA682DABE" modified="2018-01-31" version="1">MTAKIHISNLGNSLALPIPDYIVKFFNLKADDSVICSIENGKMVIEPVNQKVSKYTLDELLAGEIEPSEEISWGKPEGEEFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY55</accession>
    <name>A0A2G4EY55_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000099">
        <property type="protein sequence ID" value="PHX54464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54464">
        <property type="protein sequence ID" value="PHX54464"/>
        <property type="gene ID" value="CP500_016030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="Methyl-accepting transducer" evidence="3">
        <location>
            <begin position="196"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="144"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="341"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="428" mass="48085" checksum="69BFF653F0093C29" modified="2018-01-31" version="1">MSNPTHLAPDSTIGHLPSHNFQVSAKTPGQVVAQKFGQEPDLPGVIIIHNSQAIGMISRVKFQEQMNLPDRVELYWDNPIRLLLDYIRIPPFLLSEKWRIDDAVQAVLNRQKDLIYEPIIIEMESQDFRILDIHTLLIAQSNSLIQANKNIQRYRAERQKYIAKIKQEQAKVQEYNQLLESRKRQAEKSHHILSPQQTALAKQAQEITQQNQQFLKIAKLISAEGRLAFQATFQGANSICNNTDKILGVGKAIANDLETVNRTSRTIGEAIEQVRHLAVQVAVVTNQMGNKPNGLSQVSLEIARLASKTFELGTQIEQIASRFKLRVHALTEAARAGANVAKSVTEKIERAEMALLELEDLIAEKDVTVTSEFKDYSSVNEGSPSRSLAQEINQAEVAVSELEHIVKQQDSSQYLIQTIQDALKHKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EY61</accession>
    <name>A0A2G4EY61_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hybrid sensor histidine kinase/response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_016210</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000102">
        <property type="protein sequence ID" value="PHX54426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54426">
        <property type="protein sequence ID" value="PHX54426"/>
        <property type="gene ID" value="CP500_016210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="14"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="151"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX54426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="380" mass="41750" checksum="139C3C0BDABAADA7" modified="2018-01-31" version="1">MKHLSVPNATKADRILVVDDAPDNVLLVETILEEEGYEISSADNGFSALSQIDKCPPDLLLLDVMMPGIDGYEVTKRIRQKPELPFIPILLITAHDSASVVQGLDLGADDFIRKPVEMDELLARVRSLLRLKHSVDERNSIALQREDFVSRLAHDLRTPLVAADRMLTLMQQGALGEISLPMRDAFGTMVRSNKNLISMVNMLLEVYRYEAGGKSLSYAAVDLRQLITEVAQELAPLADAKGLSVNLDLTESAESAPIAKYPGDRLELHRLLTNLIGNAIKFTDRGSIDIRLKAANSPAFTSFTNQPLAWVIIEIQDTGPGISPTEQAKLFKRFGPGTHKRSGTGLGLHLCRQIVEAHRGTIEAKSELGKGSLFTIRLPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYC6</accession>
    <name>A0A2G4EYC6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000096">
        <property type="protein sequence ID" value="PHX54496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54496">
        <property type="protein sequence ID" value="PHX54496"/>
        <property type="gene ID" value="CP500_015780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="255" mass="28527" checksum="FA03FFB88E2A4FED" modified="2018-01-31" version="1">MKMQEADAAISEFEKSQLPSVWAALNKSQIIAEMRSRIQSPFQVNQGGQPFCGPATIAFTLINQNPLRYVEICRNLFETGSFRTQSMRSISPSIPLRSSKGNLRMPQVDWMLLSALRESENLIFPVEPNAPEIIRNISGMTKSWEMAGWAREILGSRDVKCHYAYFGGDIPALRAADAAIQAGGFAFALITAEGMLGNKPPLIPYPSHWVALTGNMLIQDRDRVSFDVYTWGKQMRVDLPKSSFEKYFWVVIAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYH1</accession>
    <name>A0A2G4EYH1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cobyrinic acid a,c-diamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_015345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000090">
        <property type="protein sequence ID" value="PHX54585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54585">
        <property type="protein sequence ID" value="PHX54585"/>
        <property type="gene ID" value="CP500_015345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="272" mass="32395" checksum="69B0A8C72A789265" modified="2018-01-31" version="1">MTKEKNKYDADLSQHRHRDTILGQLPVKAKDWAQSLPWNQRRYLLSLCYILCASTPDLQAEFLDDYTADGLVSKMFEDVDTLHRVKDYLTRFQVEKELNESDLRSYIKQFYIHSAQQVRGQNDQYLESALRFVLSTEERNNVFNYILGFEFVKIVFQMTWLQHERLARLQKNQWQFIEAYIKPIQHAHKINGIIVPKDEKIFFARRAYYVQQPDIAYKKLIELVTATFTTEMVSNCGFSISRHAQALRFDCDYIYNPEPEEARFPTELQFVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYI8</accession>
    <name>A0A2G4EYI8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_017175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000113">
        <property type="protein sequence ID" value="PHX54237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54237">
        <property type="protein sequence ID" value="PHX54237"/>
        <property type="gene ID" value="CP500_017175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="478" mass="54170" checksum="2AD7F0C9FD53CEC1" modified="2018-01-31" version="1">MQFIEKLKQIKENKYVTIFIINFILLVLLTKCDIQSSADASRIATVKSLVEYQSFAIDNSQFDNSKLFTVDKYFYNNHFYSDKPPLPAFMGAAVYFILKNIIGINFSNNFALTCYLITLLSVGVSACVGLVYFHKILLEILKTNENWANITTFLATSATLILPYSLVLNNHILGAVVIIVSFYYFLKSAECSDIISIILCGVFVSMAGSIDITCFLFIPFYFVFFLSKSIKMAGLFLLSCIPFMISYFSLNMYLSGSIIPPAMNAALWEYPGSIFSKQNLSGVATQKSFLGALRYAFTLYLGNRGFFSHTPIMFFSVMGILQFFRQKKFSYNTPYLYGITASVAFMLLYTLRTVDYGGYSYGVRWFVTPMLILCLPLSHMENQVRSSRLLKNFFVVIACISIAISLIGTYNPYTNDYTGMVSLPGGYNSKYTFLINAKNIIYDSFVMYKLCLITSTIAIYVLFYRLLQNLKQNPNTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYZ1</accession>
    <name>A0A2G4EYZ1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbon-nitrogen hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_016320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000103">
        <property type="protein sequence ID" value="PHX54407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54407">
        <property type="protein sequence ID" value="PHX54407"/>
        <property type="gene ID" value="CP500_016320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX54407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="270" mass="29906" checksum="6B3649C2070266F6" modified="2018-01-31" version="1">MKSYLAAAIQMTSLPDLQKNLVQAEELIDLAVRQGAELVCLPENFPFMGEEEEKIAASEAIGQQSEKFLKTMAQRFQVTILGGGFPVPTEGGKVYNTCLLVDPNGRELARYKKVHLFDVNVPDGITYRESSTVKAGEDLPPVYASPELGTLGLSVCYDVRFPELYRHLSQKGADVLFVPAAFTAYTGKDHWKVLLKARAIENTCYTIAPAQTGHHYGRRQTHGHAMIIDPWGVVLADAGDEPGLAIAEINPDRLEQVRRQMPSLQHRVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYZ7</accession>
    <name>A0A2G4EYZ7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pgsA</name>
        <name evidence="13" type="ORF">CP500_014470</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="10">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000080">
        <property type="protein sequence ID" value="PHX54742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54742">
        <property type="protein sequence ID" value="PHX54742"/>
        <property type="gene ID" value="CP500_014470"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00560">
        <property type="entry name" value="pgsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="PHX54742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="172" mass="18881" checksum="ED1867B79E9B010A" modified="2018-01-31" version="1">MNLPNLITFSRLLGVPFLLYGLYNPTVQSRWICVAIFVVAAATDWLDGYLARKLNQITDLGKFLDPLVDKLLVLAPLLVLIELGKVPAWGVFLILGRELTIAGWRVNKTTISGANIWGKLKTVSQIVAIALLIAPLSDAWNIPALIAFWVSVALTLISGAIYLWPSKVADEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ24</accession>
    <name>A0A2G4EZ24_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1822 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_014225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000078">
        <property type="protein sequence ID" value="PHX54775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54775">
        <property type="protein sequence ID" value="PHX54775"/>
        <property type="gene ID" value="CP500_014225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014951">
        <property type="entry name" value="DUF1822"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08852">
        <property type="entry name" value="DUF1822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="490" mass="55646" checksum="F7DA00360405A800" modified="2018-01-31" version="1">MDTIQTNSLTMALSRENHETARKFSVQQDTVEKGEQVYLNTLAILGVRSFLDWLGIETDLNAGDSWHSVVRCFQDVADLVIPNLGKLECRPVLPGQTVISLPPEVTEDRIAYIGVQFQEQLNEVQLLGFYPTIDPQAPLEEIEIANLQPIETLIDYIDRLESAHFFLPNEEVAIKVRDRLAIQSISEIITQLERIYRTYNKYERRYAGGEFLASYLPTTKGVSFRGSIPVTDREEFDDSQQTELQDLAEELLEKLDEIWGDDSSDQLVNSDSLLDEVWGDKNLDQLVDSESLLDETFVDYDSDQLFDTVSLFYESSSKIKHIEQPVIVPLSQSQSGLINLSEWLQNPEDSQYHWQPLELFLSNQEGNLIFRFASAPRSRSADAETPTRSVSKVKEIPLPGHPLVLIINCQLESDGRRDILVRLYPSTEEETYLPQGVQLIILDESGEVFLEAQSRSADNWIQLEFRGEAGEPFSIKVVFGDLSVTDNFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ60</accession>
    <name>A0A2G4EZ60_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AI-2E family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_014390</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000079">
        <property type="protein sequence ID" value="PHX54768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54768">
        <property type="protein sequence ID" value="PHX54768"/>
        <property type="gene ID" value="CP500_014390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="363" mass="39170" checksum="B66976537EBBF1F4" modified="2018-01-31" version="1">MSEQRITISIPNLLLIVASSLLLVLLWQLRSLLVILMISVVLAASIVPIVNWAETRRLPRWLAVIMVYLALIGGLSGTVVLIGPTVIQQIELLLRQLPVYAESLETVATSLASRLTDDAPTLVGQLLDTQSLTNWLIRSSQQLILRSYSLTRGILGGFFSLVLALFISGYMVADSDTLIKSLVQFFPKPWDEKLAAQATPIGQRMGSYIRGRVLVSGILGIFITTGLSILGMPEFSLGLGAIAGVTNLIPFIGPVLGAVPALIVALAKGGWVFLWVLLLFIIIQNLETYVLDPLLVGSSVGVHPLYQLLSVLGGVQVLGIIGAVIVPPWFAGVAALIENLYLKPKLRSEHRSAITQAKNNSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZ93</accession>
    <name>A0A2G4EZ93_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_013955</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54829">
        <property type="protein sequence ID" value="PHX54829"/>
        <property type="gene ID" value="CP500_013955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="358" mass="37941" checksum="C8627CB88F5870E4" modified="2018-01-31" version="1">MKNWKSILLYIGVVYIVLLLGPIAGFDLPKIIGEIIRSPEVLIQQLLVGLVNGALIAIIALGYTMVYGIIELINFAHGDLYMLGAFASLTVFGAFGIQDGAPLGIAIPVMLVALIVCSVFCAGLNIVVEKYAYRPLRNAPRLAPLISAIGVSFIFQNMGLFWGGLKAFIPVMGSNSAAPKSFPDLLPRVDILKAMGIQTSIVFTTKDLIVLVVALVLMILLHVFVQYTRLGKAMRATAQSRDAAKIMGINVDQIIALTFLIGGALAGSAGILVGLYNNTIVFTMGFTAGLRAFTAAVLGGIGNIVGAMLGGVLIGVLSSLSDQYLSSRWTNAWVFGVLVVILAFRPGGLLGENVQEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZA8</accession>
    <name>A0A2G4EZA8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">7-carboxy-7-deazaguanine synthase</fullName>
            <shortName evidence="5">CDG synthase</shortName>
            <ecNumber evidence="5">4.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queE</name>
        <name evidence="7" type="ORF">CP500_014050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:27974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="EC" id="4.3.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </cofactor>
        <text evidence="5">Binds 1 S-adenosyl-L-methionine per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.99.3" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000076">
        <property type="protein sequence ID" value="PHX54846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54846">
        <property type="protein sequence ID" value="PHX54846"/>
        <property type="gene ID" value="CP500_014050"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00917">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024924">
        <property type="entry name" value="7-CO-7-deazaguanine_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000370">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="24"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="18"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="43"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="122"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX54846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="208" mass="23289" checksum="B2578ADA4C665990" modified="2018-01-31" version="1">MSILQVKLPIHETFQSTVQGEGFWTGTLVDFIRLAGCPVGCPWCDTGYANGGKGLPIVPRSIAQLLAQLQSPRVVITGGEPFIHRDLPELVEALLAADKQVSIETSGAYWLDISPLAWITLSPKEHVNPKYPVKELFWTRSNEIKLVVSTGEEVEFYHNHLANNVNIPVFLQPEWNSKISVIPIILELLKQNHSYRLSLQTHKFIGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZC8</accession>
    <name>A0A2G4EZC8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_013870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000075">
        <property type="protein sequence ID" value="PHX54864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54864">
        <property type="protein sequence ID" value="PHX54864"/>
        <property type="gene ID" value="CP500_013870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="264" mass="28318" checksum="9AB70DD4463B3467" modified="2018-01-31" version="1">MNYLLLSFFSFFVGIIVGLTGVGGASLITPMLIFVFQVPASVAVSSDVVAATLMKVVGGCKHWQQKTLDLQVVKWLALGSVPGSLGGVWILHCIKYSENPNLDSILLRCLGVAIALIVALSLTQLLLKIFLPNLKLPQPPEWDLNTNFGRILTVSAAAILGCIVGITSVSSGAIFAFLLIAFFRLDSTKLVGTDISQAAILLLFTSLGHLSLGTVDWSLVLPIWLGSVPGVLVGAKFCQIMPQRPLKFAIYGMLAMASWKLYQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZI2</accession>
    <name>A0A2G4EZI2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_013580</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000073">
        <property type="protein sequence ID" value="PHX54919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54919">
        <property type="protein sequence ID" value="PHX54919"/>
        <property type="gene ID" value="CP500_013580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="PTHR43029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="9">
        <location>
            <begin position="27"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX54919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="459" mass="48316" checksum="A15DBB14F85C1E61" modified="2018-01-31" version="1">MNNALAQEAAPAAAAVVENPIDSGDTAWMLVSSALVLLMTPGLAFFYGGLVRSRNVLNTMMMSLVMMGLIGVTWTLWGYSLAFDVSTPVSEGFGKGFETFIGGFDWMFLNGVAADKPDPIGYAPTIPHQVFMVYQMMFAIITPALISGAIVERVTFKTYFWFVLLWSTFIYSPLAHWVWGRGWMGAMGALDFAGGTVVHISSGVSAVVAAWVIGPRKDFQSKPHTPHNVPYVLLGIGLLWFGWFGFNGGSALGSGSLATVAFVTTMISAAAGGLTWTIIEWVLRGKPTAVGIASGFLAGLVGITPAAGYVLPIGALLIGSITSVCCFFAVSLRVKLGFDDSLDTFPVHGVGGTVGAILTGVFATKAVNAAGNDGLFSGNPGLLLTQFITVVATYVFAAIGTFVILKILAQFMELRVPSSAEDQGLDIGEHGEEAYGEDFAGGFSALDSSSLFAPKNVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZM6</accession>
    <name>A0A2G4EZM6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1818 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_013150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000070">
        <property type="protein sequence ID" value="PHX54964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54964">
        <property type="protein sequence ID" value="PHX54964"/>
        <property type="gene ID" value="CP500_013150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.31.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014947">
        <property type="entry name" value="DUF1818"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009044">
        <property type="entry name" value="ssDNA-bd_transcriptional_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08848">
        <property type="entry name" value="DUF1818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54447">
        <property type="entry name" value="SSF54447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX54964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="13485" checksum="0ADE3C67AEBFAE4A" modified="2018-01-31" version="1">MVDRVIKTGDGWRLGWNPDAADFQGLVGGDDWAIELTEAELQDFCRVLAQLAATMSEMASELMDEEKIAIEAESDLVWMEVEGYPQAYSVQLILNGGRRCEGFWPATAVSGLVQATKILKVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZS2</accession>
    <name>A0A2G4EZS2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_012945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55016">
        <property type="protein sequence ID" value="PHX55016"/>
        <property type="gene ID" value="CP500_012945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030974">
        <property type="entry name" value="Restrict_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04435">
        <property type="entry name" value="restrict_AAA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="318"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="545" mass="62906" checksum="8D929A3938DEF224" modified="2018-01-31" version="1">MKLLRVHIISAKTCGGLLDGLDLWLRSPLNDYSGFDPLCLIGPNGAGKSQFLQVLAEIFQSVFHRCISEEERVEGNPDLQFELEYLIHPDDDQLPVRVRISRKASSRNRRAFVIERRDEDEYDWINCDLNDPKTRALLPEKIIGYTSGDNETLSVPFLVSRSGYANEVGGGALNAARRDRPIPDTRLILIDYGTHLEVLVANLLLGDVPQWEALLQDAQLKDLHSFRCIVQLAHSVAPKLPSRKGSQNSRKGVQLTKELEQYLDQLKRCATCYTYDNKTETYTFDYWINDQTREAFRSFWNNTLDLYSSFHKLAMLNDLALPRETRKRFQKETKERRFASRLPEPQDEDKVFRFERVMFKAKRTGKEVDYVSLSDGEHQLGQILGTFCMLSSPNMLFLLDEPESHFNPLWRVKFISRILDLPTRDGDRRKTSKATEQDCLLTTHSPFVPSDMHREKVFIFSKDEEGKIQVQNPNIETFGATFDTIIEECFNVRPPMSQVPLDEIKKLMKSEYREEIRAGMQQLGDSVEKAFLADRLRQLPNRDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZS3</accession>
    <name>A0A2G4EZS3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_013080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55009">
        <property type="protein sequence ID" value="PHX55009"/>
        <property type="gene ID" value="CP500_013080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="316" mass="35344" checksum="406F5D8339C7CAE7" modified="2018-01-31" version="1">MANQLPPVLVTFDADVLMAGRTQIWQEYAKVGNCYLPEVVYDEIDYLTGKAVEKAQEQVAREFMRFFADSGWIITDAQETHRSLEPSIKNQSKAAMLVVATAQCVYGLAQEHPDALVIFVSNSQPLLKRIASVGSANLCGITGAMLLNWARKAERPAAATQQLQSLMRTLADRKSTQRSRSRIEEDTVNKTRSSPSKFTGTRSNLEIKSATSSTKTNKTPFTEHRSSSSPPKNPPRSQEEPPEMEPAVYRMKYITPPKKRGDNFISHAFNFLGALFFLTVAVGILWRVCDVKSFRKTFVPALPKPVQQFVKSIDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZU6</accession>
    <name>A0A2G4EZU6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ</fullName>
            <ecNumber evidence="2">2.1.1.200</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">tRNA Cm32/Um32 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trmJ</name>
        <name evidence="4" type="ORF">CP500_013005</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>S-adenosyl-L-methionine + uridine(32) in tRNA = 2'-O-methyluridine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42936"/>
            <dbReference type="Rhea" id="RHEA-COMP:10107"/>
            <dbReference type="Rhea" id="RHEA-COMP:10290"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.200"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>cytidine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42932"/>
            <dbReference type="Rhea" id="RHEA-COMP:10288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10289"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.200"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.200" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000068">
        <property type="protein sequence ID" value="PHX55028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55028">
        <property type="protein sequence ID" value="PHX55028"/>
        <property type="gene ID" value="CP500_013005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004808">
        <property type="entry name" value="LasT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00050">
        <property type="entry name" value="rRNA_methyl_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX55028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="271" mass="29870" checksum="497F3979FBC23DBC" modified="2018-01-31" version="1">MPHANIRIVLVEPAGPLNVGSVARVMKNMGLHQLVLVNPQCDYLGEEARLMAVRAADILENARVVESLPEALVGCTRAIATTGDDRPIATKRENPADALPWLLEAPSALIFGREDCGLTNAELNYAQRLIRIPSSDAYTSLNLAQAVAICCYELYREAGIRKKALRPRSGYEEGTELIASATFENLEGYYQKLETVLLKIGYLHPHTADSRMAKFRHLYNRAYPTVDEVAMLRGTLRQIEWALKSCAIAPISDILDGALPDCPGDTQQPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F068</accession>
    <name>A0A2G4F068_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TVP38/TMEM64 family membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_012325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55162">
        <property type="protein sequence ID" value="PHX55162"/>
        <property type="gene ID" value="CP500_012325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="PTHR12677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="243" mass="26657" checksum="C58E459183E555AB" modified="2018-01-31" version="1">MPTKKIQDFVRVNFKRIFLLFAIALFLALLILATKSSYIQDVLRIVLIQIQDLGWWGPVAFVVTYNLATVLFIPGSVLTLGGGVIFGLWWGSIYVFVAATLGATFAFLIGRYLSRDRVVKYMEAHPKFKSLDRAVSQEGLKIVFLTRLCPLFPFNLLNYALGITQVSLKDYVLGSFGMIPGTVMYVYSGSLVGDLAAIGAVTGSTNPQDSAVKWLINIISFIATVAVTVSITRIASKALEESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0J8</accession>
    <name>A0A2G4F0J8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_011575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000058">
        <property type="protein sequence ID" value="PHX55280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55280">
        <property type="protein sequence ID" value="PHX55280"/>
        <property type="gene ID" value="CP500_011575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039554">
        <property type="entry name" value="HigA2-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13744">
        <property type="entry name" value="HTH_37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_37" evidence="1">
        <location>
            <begin position="13"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="121" mass="13330" checksum="25539195A430EDA8" modified="2018-01-31" version="1">MSENTITQATDNIFLDLGFSAQEADNLLIRSQLMLALLHQIKHHGWTIDQTAQHLKQSRDEIKALSQGKIGQFSVDTLIVMLNAVGMTVKVKICPPGSLSRSPTIESTLIFSNAMPYSFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0M0</accession>
    <name>A0A2G4F0M0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ADP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
            <ecNumber evidence="14">4.2.1.136</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">ADP-dependent NAD(P)HX dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">nnrD</name>
        <name evidence="17" type="ORF">CP500_011430</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 15">Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 14 15">
            <text>(6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32223"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 14 15">
            <text>(6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32235"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="15">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 15">In the C-terminal section; belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">In the N-terminal section; belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.136" evidence="14"/>
    <dbReference type="EMBL" id="NXIB02000057">
        <property type="protein sequence ID" value="PHX55309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55309">
        <property type="protein sequence ID" value="PHX55309"/>
        <property type="gene ID" value="CP500_011430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NADHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052857">
        <property type="term" value="F:NADPHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030677">
        <property type="entry name" value="Nnr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017184">
        <property type="entry name" value="Nnr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12 14 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14 15" id="KW-0520">NAD</keyword>
    <keyword evidence="9 14 15" id="KW-0521">NADP</keyword>
    <keyword evidence="7 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="16">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR017184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="PHX55309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="484" mass="51471" checksum="621EB8F8A35AD6D2" modified="2018-01-31" version="1">MGNFQLPAIGVLVGPGHNGGDALVVARELHFQGFPVFVYCPFSKLKELTGCHAEYLRSLNIPFFDTIEPLKNCDLFIDGLFGFGLEREINAPVSTAIDEINQLNKPVFSIDIPSGIHTDTGEVLGTAIRATHTFCLGLWKLAFLQDRALEYVGTSELIDFDIPLADIVAILGDFPAVQRITKASAIQSLPLPRSPIAHKYTNGHLLIIAGSARYNGAAILSALGARASGVGMLSIAVPESMKPMLSNQLPEALVIGCPETSNGAIKDLPVGIDLGIYDAIACGPGLTLEAAIAVESVLECDRPLVIDADGLNILAQLGTVPILSERSALTVITPHPGEFKRLFPELADKMGDRIAVTQQAAQLTGAVVLLKGARVCICSVDEGDSLRDSYASRTITYLNPESTPALARGGSGDVLTGLLGGLIASALAKPSKRIGRKSPPKSVVETAVWWHARAGIMAAKERTELGVDAFTLTQYLIPALREFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0T2</accession>
    <name>A0A2G4F0T2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Pyruvate dehydrogenase E1 component subunit alpha</fullName>
            <ecNumber evidence="2 7">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pdhA</name>
        <name evidence="9" type="ORF">CP500_011195</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="2 7"/>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55356">
        <property type="protein sequence ID" value="PHX55356"/>
        <property type="gene ID" value="CP500_011195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017597">
        <property type="entry name" value="Pyrv_DH_E1_asu_subgrp-y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03182">
        <property type="entry name" value="PDH_E1_alph_y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7 9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="E1_dh" evidence="8">
        <location>
            <begin position="28"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX55356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="345" mass="38285" checksum="AA5C498547D87BB6" modified="2018-01-31" version="1">MVQERTLPAFDATSVTISRDEGLMLYEDMVLGRFFEDKCAEMYYRGKMFGFVHLYNGQEAVSTGVIRSMRRDSTDYVSSTYRDHVHALSAGVPAREVMAELFGKETGCSKGRGGSMHMFSAEHRLLGGYAFVAEGIPVATGAAFQSKYRREALGDEGSDGVTACFFGDGAANNGQFFECLNMAALWKLPILYVVENNKWAIGMSHERATSDPLIYKKAHAFGMAGVEVDGMDVLAVREVAKEAVARARAGEGPTVIEALTYRFRGHSLADPDELRSKEEKEFWFPRDPIKRLAADLIDRTLATAEELKAIEKKIEAVIDDAVDFAEKSAEPDPSELYRFIYAEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0Z2</accession>
    <name>A0A2G4F0Z2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_012130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000063">
        <property type="protein sequence ID" value="PHX55127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55127">
        <property type="protein sequence ID" value="PHX55127"/>
        <property type="gene ID" value="CP500_012130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="61" mass="6980" checksum="1DD5C17393110750" modified="2018-01-31" version="1">MVQAPHLSVESIQNPQAPAFIRRINPKSKIQNRLTATQMRQLPFPTTLMDFVPALRFFTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F130</accession>
    <name>A0A2G4F130_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 19">Adenosylcobinamide-GDP ribazoletransferase</fullName>
            <ecNumber evidence="7 19">2.7.8.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18 19">Cobalamin synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 19">Cobalamin-5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">cobS</name>
        <name evidence="20" type="ORF">CP500_010775</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16 19">Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23560"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="ChEBI" id="CHEBI:60493"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16049"/>
            <dbReference type="ChEBI" id="CHEBI:10329"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 19">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="19">Cell membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 19">Belongs to the CobS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.26" evidence="7 19"/>
    <dbReference type="EMBL" id="NXIB02000052">
        <property type="protein sequence ID" value="PHX55455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55455">
        <property type="protein sequence ID" value="PHX55455"/>
        <property type="gene ID" value="CP500_010775"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051073">
        <property type="term" value="F:adenosylcobinamide-GDP ribazoletransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008818">
        <property type="term" value="F:cobalamin 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00719">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003805">
        <property type="entry name" value="CobS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34148">
        <property type="entry name" value="PTHR34148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02654">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00317">
        <property type="entry name" value="cobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 19" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 19 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00015850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="PHX55455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="265" mass="28129" checksum="DFA5A750E966CA4B" modified="2018-01-31" version="1">MMDDKLVRSTVEFFRNQGAAIAAAVAFYTCLPVPMSWTLEFRGIARFAPAIGLLIGGILGIADLGLHLLGMPVLTRSALVVVLGIAVTGGLHLDGAMDAADGLAVPDPVRRLEVMRDSVTGAFGAIAAVVILLLKTAALTDLNEYRWLALMGVAGWGRWGQLVSIARYPYLRAEGKGAFHKESIYSAFDFIPGVLLLLSLSVLQVVWEGDRWLLAVGMALGGSAIGILTGAWFNHRLGGHTGDTYGAVVEWTEALLLCLLAALQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F138</accession>
    <name>A0A2G4F138_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_010325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55494">
        <property type="protein sequence ID" value="PHX55494"/>
        <property type="gene ID" value="CP500_010325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="235" mass="25226" checksum="14B90C78D6B390F7" modified="2018-01-31" version="1">MIEQDRSTRTLAVDIGGSGIKVMVLDAEGIPQTERSRLETPQPPKPEPVLEAIASLAGGQGEFDRVSVGFPGVVCHGITKTAANLDPSWIDFDLATTLKDRLGKPVRVANDADIQGLGAIAGTGVELVVTLGTGFGSALFVDGMLVPNLELGHHPFRKGETYEQQLGRLALDTVGAKRWNRRLEKAIICLQNLFSLDHLYIGGGNNKKIMFELPPKVKIVPNVSGLLGGIALWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F185</accession>
    <name>A0A2G4F185_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">D,D-heptose 1,7-bisphosphate phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_010425</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the gmhB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="5"/>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55513">
        <property type="protein sequence ID" value="PHX55513"/>
        <property type="gene ID" value="CP500_010425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004446">
        <property type="entry name" value="Heptose_bisP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006543">
        <property type="entry name" value="Histidinol-phos"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42891">
        <property type="entry name" value="PTHR42891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004682">
        <property type="entry name" value="GmhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01656">
        <property type="entry name" value="Histidinol-ppas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="16"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="50"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="111"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="8">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to substrate recognition" evidence="8">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="8">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR004682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="193" mass="21540" checksum="A32A21C1AA0E2B79" modified="2018-01-31" version="1">MKRAVFLDRDGVLNIEAGYIHQVEDLHLIPGVAQAVRRLNDKQIFCCLVSNQSGPARNYYPVSHVEALHKRLCQLLENEAGAKLDALYYCPYLSEAEGGTNPEFTRYTTWRKPNTGMLVAAAWEQDLDLRNSFMVGDKATDVDMAHNAGCTGILVQTGYGESVLSGKYQHHTKPDFVAANLVVGVDWILKHFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1B2</accession>
    <name>A0A2G4F1B2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carbohydrate ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_010560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000050">
        <property type="protein sequence ID" value="PHX55536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55536">
        <property type="protein sequence ID" value="PHX55536"/>
        <property type="gene ID" value="CP500_010560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="68"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="272" mass="30070" checksum="0B2C718F98F7D640" modified="2018-01-31" version="1">MTKSFDRSRALELLNFILLLAGAALVLLPLAAVFLVSLSPSGVGVKVTGWTFANYQEAWRRGNFLLAFVNSTLVAIAVTGFQVITSALAGYALARLKFRGRQALILAVLATLVIPFQLLVIPIFLVLKWGHLLNTYGALILPTAANGFGIFLLRQYFMTIPVELEEAAMLDGANRWQVLWQVMLPLARPALVTLFLFTFIGEWNDLFKPLVFTTRPELRTVQLALAEFQEQFTSSWPLLMAAVVIGTLPVVLLFLAGQRQFMRGIATTGIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1U9</accession>
    <name>A0A2G4F1U9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ATP-dependent Clp protease ATP-binding subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CP500_009495</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55718">
        <property type="protein sequence ID" value="PHX55718"/>
        <property type="gene ID" value="CP500_009495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="13">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="12">
        <location>
            <begin position="416"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="PHX55718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="825" mass="91460" checksum="80FECBF25E765D36" modified="2018-01-31" version="1">MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDARIEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLSKVRTQVIRMLGETAEVAATGGGARTKTPTLDEFGSNLTQMAVDGKLDPVVGRQKEIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIANNDIPDILEDKRVVTLDIGLLVAGTKYRGEFEERLKKIMDEIRTAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPTVDETIEILFGLRERYEQHHKLKILDTALEAAAKLSHRYISDRFLPDKAIDLVDEAGSRVRLINSQLPPAAKELDKELRQVLKDKDEAVRSQDFDKAGELRDREMTIKAEIRAISQAKKTDSATRGETDPSPVVTEEDIAQIVASWTGVPVNKLTESESEKLLHMEDTLHQRLIGQEEAVKAVSKAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKALAGYFFGSEDAMIRLDMSEYMERHTVSKLIGSPPGYVGYNEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNMLLQILEDGRLTDAKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSDNQADATYNRIRSLVNEELKNYFRPEFLNRLDEIIVFRQLNREEVKEIAVIMLKEVFGRLTEQGITLEVTEKFKERLVEEGYNPSYGARPLRRAIMRLLEDSLAEEILSGRIKDGDIAVVDVGEDGIVKVLQGQKRELLPQGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F234</accession>
    <name>A0A2G4F234_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1830 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55809">
        <property type="protein sequence ID" value="PHX55809"/>
        <property type="gene ID" value="CP500_008970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014964">
        <property type="entry name" value="DUF1830"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08865">
        <property type="entry name" value="DUF1830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="90" mass="10427" checksum="CA452405E8CF9768" modified="2018-01-31" version="1">MNLTINSVDSDRSVKILCWYINTTNKIQIARITNIPDWYFERTVFPGERLLFEAQPEAELEVWMSTETGAIVCDRILCDRLQVEEASTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F248</accession>
    <name>A0A2G4F248_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000039">
        <property type="protein sequence ID" value="PHX55818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55818">
        <property type="protein sequence ID" value="PHX55818"/>
        <property type="gene ID" value="CP500_008655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="406" mass="46367" checksum="1BF4CF651DECB957" modified="2018-01-31" version="1">MTLKSFDIVIVGAGPAGGHCARILAKSGRQVLLAEQNDSFNKNDFSSAATPLKTLSRFDLPESVIGSYWHKLTIKTSKVSQTWESPKSLGVVLNFAKFRAFLASEVQGNGSEVWLGYRYIKHSQANGETIVEFKQLSDGKIIQVSAKILVDATGFARAIMYEKENDKPDFLSGTGIEYLIEVEPEVYDRYANDLIFFLGDKWMPNGYSWIFPMEQNRLKVGAGRVFLDPKTVKNLEPLKKYIYLLIDEYLKSKSYKIIDKHGSTLKYSQGLKDIYCQDNIIAIGDTVSTVNFLGGEGIRHGMDGAEIAAKYIQKYLDEKISDFGDYEREMHRKFDQKWHISERLAVRKYIDDVNDVLTDKTIDYLKYMKTEDVMDILFDYKFEKISRGLGGYLIRKIKGLIERFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F250</accession>
    <name>A0A2G4F250_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bleomycin hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_008445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cellular thylakoid membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phycobiliprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55853">
        <property type="protein sequence ID" value="PHX55853"/>
        <property type="gene ID" value="CP500_008445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031676">
        <property type="term" value="C:plasma membrane-derived thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012128">
        <property type="entry name" value="Phycobilisome_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038719">
        <property type="entry name" value="Phycobilisome_asu/bsu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00502">
        <property type="entry name" value="Phycobilisome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000081">
        <property type="entry name" value="Phycocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="3 4" id="KW-0089">Bile pigment</keyword>
    <keyword evidence="2 4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX55853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="164" mass="17814" checksum="FA98EE7BDDB4C14E" modified="2018-01-31" version="1">MKSVLTTAIASADAAGRFPSTSDLESVQGSIQRSAARLEAAEKLGNNLDSVAKEAYDACIKKYPYLNEAGQANSTDTFKAKCHRDIKHYLRLIQYCLVVGGTGPLDEWGIAGQREVYRALSLPTAPYVEALSFARNRGCTPRDMSAQALTEYNALLDYAINSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2B6</accession>
    <name>A0A2G4F2B6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_008030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000036">
        <property type="protein sequence ID" value="PHX55914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55914">
        <property type="protein sequence ID" value="PHX55914"/>
        <property type="gene ID" value="CP500_008030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX55914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="375" mass="43415" checksum="9BD215A62138E726" modified="2018-01-31" version="1">MTLPERLAQDWKSRLEKDCPDENSSTRQSVVRWLLGDTPDRFETLAPNQLSIAIAAIDFLYRILISRYLGLAPEQAYRNLIGRLGGLVVLRQKIQAWVSLSRDRQRSVVDVLQEVIQEMLNSDRYLQQQVAWIAECTSDRRLQNSLLLASVEEYCLRPIRNQPLLVYRFVNYLRRSQRGGLTQVPSGDWVRLVSEQILLDDTDETVSLLDQQGMSEYQETQAWEDRQAQRQIVQAEFETYLAAQVDPLASQWLRLYLQGRSQEAIAEVLNVPIKQIYRLREKVSYHAIRVFAVKQSPELVASWLETSLQEHSLGLTPSQWQQYWDNLTPVQRQLIESLKAGKSVEAIASELKLKTNQVISEWTKLYLAAQSLRNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2I5</accession>
    <name>A0A2G4F2I5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heme oxygenase (biliverdin-producing)</fullName>
            <ecNumber evidence="2">1.14.14.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_007890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heme oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.18" evidence="2"/>
    <dbReference type="EMBL" id="NXIB02000035">
        <property type="protein sequence ID" value="PHX55959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55959">
        <property type="protein sequence ID" value="PHX55959"/>
        <property type="gene ID" value="CP500_007890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004392">
        <property type="term" value="F:heme oxygenase (decyclizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006788">
        <property type="term" value="P:heme oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19165">
        <property type="entry name" value="HemeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002051">
        <property type="entry name" value="Haem_Oase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016053">
        <property type="entry name" value="Haem_Oase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018207">
        <property type="entry name" value="Haem_oxygenase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720">
        <property type="entry name" value="PTHR10720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01126">
        <property type="entry name" value="Heme_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000343">
        <property type="entry name" value="Haem_Oase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00088">
        <property type="entry name" value="HAEMOXYGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00593">
        <property type="entry name" value="HEME_OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000343-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000343-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="249" mass="28104" checksum="72536F70112CF5DB" modified="2018-01-31" version="1">MMTNLSTRLREGTMQSHTTAENTAFMKCFLKGIVEREPLRKLFADLYFVYSALETALQSHVNDPIIGTLYFPELNRTENLVRDLVFYYGENWREEITASPAGCVYRDRIQTLSETDPALLIAHAYTRYMGDLSGGQSLKNVIRGALSLPPDGGTDFYEFSQISTPEARRVFKERYRQTLDGFPVDADTIERIVAEANVAFTLNQDVMHELEADVKAAIGEHTFDLLTRQDRPGSTERHGHGAGRESVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2J2</accession>
    <name>A0A2G4F2J2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_007780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000034">
        <property type="protein sequence ID" value="PHX55981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55981">
        <property type="protein sequence ID" value="PHX55981"/>
        <property type="gene ID" value="CP500_007780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="13986" checksum="3C0D7C65E36919B0" modified="2018-01-31" version="1">MPEFIEWLNSDQIKSLHPLEFAAEAHLRFVSIHPFRDGNGRLLMNLLLLRAGYPILIVSSQVRAAYIDAIAQAQQNDSGIHPLLDLIVDAARYSLIETLQILATASDSQSQGLPFYQEMIAVLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2R2</accession>
    <name>A0A2G4F2R2_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">DNA replication and repair protein RecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recF</name>
        <name evidence="8" type="ORF">CP500_007475</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the RecF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000032">
        <property type="protein sequence ID" value="PHX56064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56064">
        <property type="protein sequence ID" value="PHX56064"/>
        <property type="gene ID" value="CP500_007475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00365">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001238">
        <property type="entry name" value="DNA-binding_RecF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018078">
        <property type="entry name" value="DNA-binding_RecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042174">
        <property type="entry name" value="RecF_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32182:SF0">
        <property type="entry name" value="PTHR32182:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00617">
        <property type="entry name" value="RECF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00618">
        <property type="entry name" value="RECF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="SMC_N" evidence="7">
        <location>
            <begin position="2"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="424" mass="48234" checksum="4558F5C5A30DC874" modified="2018-01-31" version="1">MYLKNIHLRQFRNYLDQKVAFDAPKTILVGNNAQGKSNLLEAVELLSTLKSHRATRDRDLILDSKPMGQIEATLERQTGSIDLALTMHSQARRTCKLNGEPLRRHLDFLSVLNVVQFSCLDLDLVRGGPEIRRNWIDRLVIQLEPIYAHILQQYNQILRQRNALLKSSKEIRKANFSEPLDKMQFMGNETASSQDREEFPIPHAQFPMPNSPCPIPNSPFPIQNSELALWDAQLATAGARVIRRRDRVLERLMPLARNWHSSISGSTEVLDIKYAANIEVGQEFIAKDNLEGVRSAFLDKIQQRAIAEKFQGTTLVGPHRDDITFTINNTPARQYGSQGQQRTLVLALKLAELQLIEEVVGEPPLLLLDDVLAELDLNRQNQLLETIQERFQTLITTTHLGAFDSQWLQQTQILTVVAGQINQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2R9</accession>
    <name>A0A2G4F2R9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">(Deoxy)nucleoside triphosphate pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CP500_007125</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56073">
        <property type="protein sequence ID" value="PHX56073"/>
        <property type="gene ID" value="CP500_007125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008413">
        <property type="term" value="F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003561">
        <property type="entry name" value="Mutator_MutT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00586">
        <property type="entry name" value="mutt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="8"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="8-oxo-dGTP binding" evidence="2">
        <location>
            <begin position="41"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>8-oxo-dGTP</name>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>8-oxo-dGTP</name>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR603561-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR603561-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="PHX56073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="140" mass="15826" checksum="09E8980699B573CF" modified="2018-01-31" version="1">MNMSLSALPHKVIGVAVIWNKQGQILIDKRRKQGMHGGFWEFPGGKIEPGETIAACIEREIIEELGIVIEVGASLMTIEHNYTKFTVTLCVHNCRYVSGEPQTLECDEIRWVTLDELDQFTFPKANEQIITALRKNLTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2W1</accession>
    <name>A0A2G4F2W1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_008900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000040">
        <property type="protein sequence ID" value="PHX55797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55797">
        <property type="protein sequence ID" value="PHX55797"/>
        <property type="gene ID" value="CP500_008900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="2">
        <location>
            <begin position="104"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="307" mass="34208" checksum="9DA2C5520A92BC6C" modified="2018-01-31" version="1">MAVGKDTIFERFLSPLIRLGIDEAAMERFYKSIDWEEAGDRIRQLDLVYPEYYSSQNFHGIKGGYLNPSAAVSYDPITQYVLPPQETVVRQGLIDAVRVKPRRIIDLGCGTGSTTLMLQQAFPEAKVVGLDLSPYMLVVAEIKAQKAGLNIEWRHGNAESVGFPDASFDLVAASLLFHETPTAVSRAILRECFRLLRVGGQVAILDGNQNALRQTEWLTDIFEEPYIKSYATGSMDAWMGAAGFARVQTLDHWWVHQVTQGVKPLPGEDLEEVRVARGWNLVDSLRDSDASRTPDFDGDLQGFPTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2X5</accession>
    <name>A0A2G4F2X5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1257 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56098">
        <property type="protein sequence ID" value="PHX56098"/>
        <property type="gene ID" value="CP500_007270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009666">
        <property type="entry name" value="Uncharacterised_Ycf35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39638">
        <property type="entry name" value="PTHR39638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06868">
        <property type="entry name" value="DUF1257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="128" mass="14752" checksum="D207A82517BC85FE" modified="2018-01-31" version="1">MSHFSQIKTQIRNLNSLEAALTDLGIDWKSGPTEVRGYRGLTSNAEVVIEQENGYDLGFSWNGTEYELVADLQFWQQAWSVDRFLNKVTQRYAYHTVVNESAKQGFQVSEQKQNQDGSIRLVMQRWCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2Y5</accession>
    <name>A0A2G4F2Y5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome c biogenesis factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_007175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56120">
        <property type="protein sequence ID" value="PHX56120"/>
        <property type="gene ID" value="CP500_007175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037919">
        <property type="entry name" value="OGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366">
        <property type="entry name" value="PTHR44366"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="146"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="291" mass="32179" checksum="8F369103727A42F9" modified="2018-01-31" version="1">MPNRLPLIFLLLTVGLWTMPKPVVAQALLPYTLQIDSAQLEQTALSLAEEAVQLVRLQQYELAVPRAELATQLSPKNAQNWTLLGSLYLQLEQFPKGIDALEKAQSLSPKNPAIKFVLGEAYFRQAKYEKAVEYLQAGLKLKPDTPGALFDLGNAFYKLKRFDNAIAQYEKAFALEKNLWPAINNIGLVKYEMGDADGAIKRWEQAIAIDNKAAESMLALAVALYNKGDKAKGLAMGEAALKLDIRYAGAEFLKENLWGDRLIAATQKFLATPEMKAALAKIQDSPPSPQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F382</accession>
    <name>A0A2G4F382_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ahcY</name>
        <name evidence="9" type="ORF">CP500_006555</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4 6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56233">
        <property type="protein sequence ID" value="PHX56233"/>
        <property type="gene ID" value="CP500_006555"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="8">
        <location>
            <begin position="192"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="158"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="221"/>
            <end position="226"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="300"/>
            <end position="302"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX56233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="425" mass="46026" checksum="A48AC8B4417D0025" modified="2018-01-31" version="1">MVATLVQIKHEVKDLSLAPLGKQRIEWAGREMPVLRQIQERFAKEKPFAGIRISACCHVTTETAHLAIALKLGGADALLIASNPLSTQDDVAACLVADYGISVYALRGEDAATYERHVNTALDHRPNIIIDDGSDVVAALIQHRPNQISDLIGTTEETTTGIVRLRAMLKDGVLTFPAMNVNDADTKHFFDNRYGTGQSTLDGIIRATNILLAGKNIVVAGYGWCGKGTALRARGMGANVIVTEIDPIRAIEAVMDGFRVMPMDEAATVGDIFITVTGNKHVIRAEHFDTMKDGAMVCNSGHFDIEIDLKSLGAKSTDVKTVRSFTQEYRLNNGKSIIVLGEGRLINLAAAEGHPSAVMDMSFANQALAAEHLVTNKGKLEPGIHSIPVEVDKEIARLKLEAMGIFIDTLTPEQIEYTNSWTSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3C3</accession>
    <name>A0A2G4F3C3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1311 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000026">
        <property type="protein sequence ID" value="PHX56248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56248">
        <property type="protein sequence ID" value="PHX56248"/>
        <property type="gene ID" value="CP500_006470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009739">
        <property type="entry name" value="LprI_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07007">
        <property type="entry name" value="LprI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013633143" evidence="1">
        <location>
            <begin position="28"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="LprI" evidence="2">
        <location>
            <begin position="40"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="139" mass="15852" checksum="766B93090F73E825" modified="2018-01-31" version="1">MKYITIWATLAASSLLLTAGFLLPSQASNTPLQLAQQVNCKSPQTTLDMNMCSSQEFQTADRKLNQLYQQLQPKLTSKQQQRLTVAQRSWLKFRDESCDYEKGQFEGGTLAASTYGYCRARVTQERIKDLERYLQQASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3E4</accession>
    <name>A0A2G4F3E4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_006200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56255">
        <property type="protein sequence ID" value="PHX56255"/>
        <property type="gene ID" value="CP500_006200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="295" mass="32671" checksum="764DF2A8F10FEB29" modified="2018-01-31" version="1">MANFQLLSIGNDPIFRLGLRIACQDYPDLQIFAEVSTVTEALEVLKVRSANGEGKPADLVVFDFDGHNVRSGEMSGLAFCQQLKTLYPNLPVILLGGPLTPEWRSTLQETNINGYCPKGRDISLTMAAIDLVASGQTYWPENTAVISENEQDLAAVQTKENSPADIDHNLDFPIVSTPIHQKLLANICLSGLRQIDANLAIIKVELQDTIATGKKDFSSILDEVLLSGHRRELLAARWIVSQLLPQEGRRKKEEGRESCDSIQDKKRAIRLRSGHVMAPDSDRMVQGKKRKEGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3F6</accession>
    <name>A0A2G4F3F6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000024">
        <property type="protein sequence ID" value="PHX56314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56314">
        <property type="protein sequence ID" value="PHX56314"/>
        <property type="gene ID" value="CP500_006180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="79" mass="9181" checksum="2A1ABFA08CCCBA20" modified="2018-01-31" version="1">MSLDCLEMSSSVAPSFLQGYWQDSFNLKQHLQDFLNLDLEAIEKELEIGQQSLKEIGHRDFDWEKGMKESKAMPCPYPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3K0</accession>
    <name>A0A2G4F3K0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_006025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000023">
        <property type="protein sequence ID" value="PHX56340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56340">
        <property type="protein sequence ID" value="PHX56340"/>
        <property type="gene ID" value="CP500_006025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11616" checksum="042EE2D508D1A60A" modified="2018-01-31" version="1">MNQGAIPDENPRNLLEQLLLQDAKAGNCIVIHCGTDRLLGDVRRLIALYGGNSEDWDKMTSIEAFEINGASVQVHWFRNSQTLQEVEFKFKRQYPKTAPKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3S1</accession>
    <name>A0A2G4F3S1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ppx/GppA family phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56388">
        <property type="protein sequence ID" value="PHX56388"/>
        <property type="gene ID" value="CP500_005595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030673">
        <property type="entry name" value="PyroPPase_GppA_Ppx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001267">
        <property type="entry name" value="Pyrophosphatase_GppA_Ppx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="2">
        <location>
            <begin position="27"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="354"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="538" mass="60729" checksum="BEC1636D45F32B57" modified="2018-01-31" version="1">MVNSLASAESNRIIAAIDMGTNSFHMVVARIDPKLPAFTIIAREKDTVRLGDCDTKTGCLKSEVMERAIATLRRFQDIAKTFNAEQVIAVATSAVREAPNGRDFLKQVADELDLNVSLISGQEEARRIYLGVLSGMEFNNQSQVIIDIGGGSTELILGDSTEPRCLTSTKIGAVRLTGEFVKTDPISREEFAYLQAYIRIALERPIDELRVHFKAGETLRLIGTAGTIETLAAINAREKFGTVPSPLTGYQLSLTDLRDLVNHFRKLSYAERLAIPGMSDKRAEIILAGALILQEAMTLLGMEFLTVCDRSLREGVIVDWMLSRGLIENRLRYQGSIRQRSILHMVQKYQVNLEHSQKIADFALDLFDQTQGILHYWGTEERELLWAAAILHNSGLYVSHSAHHKHSYYLIRNGELLGYTETEIEVIANLSRYHRKSPPKKKHENFVILPKKYREVVSKLHPLLRLAVALDRRQIGAIAHFKCELRPEVREFHLHLKPVNPGDDCALELWSLDYKKPAFEYEYNLKLVATLEPNLVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3W9</accession>
    <name>A0A2G4F3W9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Purine nucleoside phosphorylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CP500_005395</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:24409"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:27643"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27647"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:11853"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000020">
        <property type="protein sequence ID" value="PHX56438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56438">
        <property type="protein sequence ID" value="PHX56438"/>
        <property type="gene ID" value="CP500_005395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16833">
        <property type="entry name" value="YfiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003730">
        <property type="entry name" value="Cu_polyphenol_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038371">
        <property type="entry name" value="Cu_polyphenol_OxRdtase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30616">
        <property type="entry name" value="PTHR30616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02578">
        <property type="entry name" value="Cu-oxidase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00726">
        <property type="entry name" value="TIGR00726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX56438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="294" mass="31631" checksum="FD9797E96923A529" modified="2018-01-31" version="1">MSLAGDRLKIFRDSECVGEPDGVTWEWQTWEGLPYLTCSLLEPWCHGFFTAQFSPRSPIDLVEVLSPGAQVYRVKQVHGNVVLKTGEVSPVSAGSPGSETVAEIYSEADGLVAERPFEAIWVCTADCVPVLIADDRTGLVAAVHAGWRGTAAKILPEAIDRLVAVGSQLENLRIAMGPAIAGQVYQVSVEVAAKLGATIVPNSAVSATADSILEFLHQLPETPVFADPAPGKVRLDVRRCNALQLQQLGINSSQVAIAPHCTYSDSDRFFSYRRDPLKKVQWSGIVSRGATTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F442</accession>
    <name>A0A2G4F442_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cyanophycin synthetase</fullName>
            <ecNumber evidence="7">6.3.2.29</ecNumber>
            <ecNumber evidence="6">6.3.2.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cyanophycin synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cphA</name>
        <name evidence="12" type="ORF">CP500_004940</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[L-4-(L-arginin-2-N-yl)aspartate](n) + ATP + L-aspartate = [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13277"/>
            <dbReference type="Rhea" id="RHEA-COMP:13728"/>
            <dbReference type="Rhea" id="RHEA-COMP:13733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137986"/>
            <dbReference type="ChEBI" id="CHEBI:137990"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ATP + L-arginine = [L-4-(L-arginin-2-N-yl)aspartate](n+1) + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23888"/>
            <dbReference type="Rhea" id="RHEA-COMP:13732"/>
            <dbReference type="Rhea" id="RHEA-COMP:13733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137986"/>
            <dbReference type="ChEBI" id="CHEBI:137990"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.30"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.29" evidence="7"/>
    <dbReference type="EC" id="6.3.2.30" evidence="6"/>
    <dbReference type="EMBL" id="NXIB02000018">
        <property type="protein sequence ID" value="PHX56505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56505">
        <property type="protein sequence ID" value="PHX56505"/>
        <property type="gene ID" value="CP500_004940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071161">
        <property type="term" value="F:cyanophycin synthetase activity (L-arginine-adding)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071160">
        <property type="term" value="F:cyanophycin synthetase activity (L-aspartate-adding)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009059">
        <property type="term" value="P:macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011810">
        <property type="entry name" value="Cya_phycin_syn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044019">
        <property type="entry name" value="Cyanophycin_syn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18921">
        <property type="entry name" value="Cyanophycin_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02068">
        <property type="entry name" value="cya_phycin_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="11">
        <location>
            <begin position="224"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="PHX56505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="906" mass="97694" checksum="25CBAA21CD542EE7" modified="2018-01-31" version="1">MKILKIQTLRGPNYWSIRRQKLIVMRLDLEELADKTTAQIPGFYEGLLTVLPSLYEHFCSPGRQGGFLQRVKEGTMMGHVIEHVALELQEMAGMPAGFGRTRETSTPGTYQVVLEYQNEQAGRYAARAGVRLCQSIVSTGTYSPTELAQDLRDLTEFAASASLGPSTETLVKEAEARGIPWMQLSARFMIQLGYGVHQKRIQATLSNRTGVLGVELACDKEGTKNILGSAGVPVPRGTVIHYLDELESAIEEVGGYPIVIKPLDGNHGRGITIDINSREVAEEAYDLASAASKTKSIIIERYYTGRDHRVLVVNGQVVAVAERVPANVVGNGRLTVEQLIDEVNRDPQRGDGHDNVLTRIVVDKLSLDLLNKQGYSMDSVLPVGERVFLRATANLSTGGIAVDRTDEIHPENVWLFSRVAKIIGLDIAGIDVVTSDISKPLRDTNGVIVEVNAAPGFRMHVAPSQGLPRNVAGAVMDMLFPSPGVSRVPILAVTGTNGKTTTTRLLAHIVKQTGQITGYTTTDGTYIGEYLVESGDNTGPQSAQLILSDPTVEVAVLETARGGILRSGLGFDQCDVGVVLNVAADHLGIGDIDTVEQLATLKSVLVESVMPKGYAVLNADDPLVARMAQNVKAQIAYFSMNPDNELVARHTAAGGLAAIYENGYLSILKGDWTLRIEQAVNVPLTMGGRAPFMIANALAACLAAFAQGLKIEDIRAALSSFQASVGQTPGRMNLFNLGKYHALLDYAHNPHSYKALGSFVQNWDGMRIGVVGAPGDRRDEDFVTLGKLSAEMFDRIIVKEDVDRRGREPGVVAKLICQGIAEAISARTADRSKVEYELILDETIAVNKALDEAPAGSLVVILPEGVTKALALIEARKPIQESVEVQNGLVKSKSQESLKPTVVNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F453</accession>
    <name>A0A2G4F453_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000017">
        <property type="protein sequence ID" value="PHX56563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56563">
        <property type="protein sequence ID" value="PHX56563"/>
        <property type="gene ID" value="CP500_004760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="131" mass="14320" checksum="1E05A04488E305E5" modified="2018-01-31" version="1">MESTQKKSSDSLVRKGDRIKQIFALVSMAGFAGSTIFGMVSLFSSGLSSQHQQKQAAVAVSQESLLAAKERGYVTVLQREPQNQTALEGLANVRLEMDNRVGAIEPLEKLVKLNPDRADYKQLLGQVKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F479</accession>
    <name>A0A2G4F479_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_004445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000016">
        <property type="protein sequence ID" value="PHX56593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56593">
        <property type="protein sequence ID" value="PHX56593"/>
        <property type="gene ID" value="CP500_004445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="918" mass="101786" checksum="B2C96282CA0C7054" modified="2018-01-31" version="1">MLNTAKLFEENPIQGNTQVFSAEIPDLFGSKFDPLNPTKNMGVRETNVLFDTNSDLTQKPELVAAATGGAIDLSEQFSNFGTLETTDNNLKFDRNLISEPDTDIKVQRDELTGMDFAVSETGENPELFASRNSSPFPSENWAFDFKNYTIDHQGLNTLNIKVGYELKPGITKQEYPDFVPIYKSIDNFLVNYPNETDFWEILNKNLTKKVLDENPVLTDIILELEILPTDRLPYDRASTVFRSQSGKIEENFDFSFKDYAINHQGLNKLNLDVNYQYKPGITQPEYPDFVPIYKGIDKFLTNYPNETDFWEIVNKKLTKDILNENPALAGIKIDLNVLPSQSLPYNRTSKVTRTQPSNPQGTFLVGNTRGDNILRFDGNTGNFIDEFIPAASGGLSKPDTVIFGPDGNGDGKSDIYIASGDKPGKSGETGASAVLRYDGITGAFIDKFVGDNPNTLTDETGGLSRPYGLAFGPDGNFYVSSFLTDQILRYNGKTGQFIDVFAAGNQQAGGLNGPNGLVFAPDGSLYVTTQGSVARNGRADFSANFLSQVLRYNLETKQFSIFASPDVSPRSQGFVSLLGLAIGPNDGDLYVSDFANDIRRYKLKTGELVKTLSTNYTETVPSSNYVGSLAFSPIGNLFAVGFDNRANANSAGAILRYNGKTGDPQPIGGNIGSSNNSIFVPPDSKLKRPVGITFFPADSQLTEKFNFTLANYPIDHQGLNNLNIDVNYQYQNGIENSQYPDFVPIYKSLENLLVNYPNETDFWEVVNKNVTQKVIAENRALASVTVDLDILPTNRLPYDRSSTVTRTQDGKLGEAWDFKFANYSIDHQGLNNLNIDVKYQYKPGITTAEYPDFVPIYRSIDNFLANYPNETDFWEVVNKKLTKKVLAENPALDSLQIGLEVLPTNRLPYERSSIVAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4G6</accession>
    <name>A0A2G4F4G6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system HicB family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56650">
        <property type="protein sequence ID" value="PHX56650"/>
        <property type="gene ID" value="CP500_004385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031807">
        <property type="entry name" value="HicB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15919">
        <property type="entry name" value="HicB_lk_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HicB-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="63" mass="7252" checksum="A5CA79BEF20CBB6B" modified="2018-01-31" version="1">MNVSKQEFYVIIERDEDGYYVGEVPQLKACYSQGETIDELIVNIKEVIALCLEEEGDRLLPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4J3</accession>
    <name>A0A2G4F4J3_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_004085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000014">
        <property type="protein sequence ID" value="PHX56680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56680">
        <property type="protein sequence ID" value="PHX56680"/>
        <property type="gene ID" value="CP500_004085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="98" mass="10871" checksum="3AB198142E4AC45E" modified="2018-01-31" version="1">MSLTQTQVTYTEALANLDELCEQVISDRDTIIITRSDGENVALIAADELASLIETVYLLRSPKNADRLLSTLKDAQARIVKPQTIRELRQELGLGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4N1</accession>
    <name>A0A2G4F4N1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nitrate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_003570</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56706">
        <property type="protein sequence ID" value="PHX56706"/>
        <property type="gene ID" value="CP500_003570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005890">
        <property type="entry name" value="NO3_transporter_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01184">
        <property type="entry name" value="ntrCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="22"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="370"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="385"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="536" mass="56927" checksum="2C2C9C16F1005907" modified="2018-01-31" version="1">MQTINTEETTKAIDSKTATSFLSIKDVSKVYPTAKGPAVILDGVNLNINEGEFICLIGHSGCGKSTLLNMIAGFNGPTEGEIALEGARITEPGPDRMVVFQNYSLLPWLTATENIHLGVETVYPDKSADEHNKIVQQHLELVGLTEACNKRPGQLSGGMKQRVAIARALATRPKLLILDEPFGALDPITREELQEELLKIWREYKITVIMITHDIDEALFLSDRIVMMTNGPAAKIGEDVPIPFSRPRNRTRIMEDPKYYELRNFALEFLFSRYAHTDGDEETETALPPLPASAFRSESVPVGLPKTVAPAAFGPHASEPSEASRIKGAVLGVSWLFAMAVLAAVNMSSVSSQQKQKLAATAPQAPIAVISSPPTPAAPTAAATTPPTAAATTAPTAAATTAPTAAATTAPTAAATTPPTAAATTAPTAATTSATSQIADAELDAIGQKLYAQIDQNWSTTPTFTESLTYRVKVKQNGDIVQFDPTNQAAKDFLQETPLPVLQIPAGTPAGAEKTAEFQVTFSPSNGGKLEVKTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4U5</accession>
    <name>A0A2G4F4U5_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CASH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_003880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000013">
        <property type="protein sequence ID" value="PHX56759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56759">
        <property type="protein sequence ID" value="PHX56759"/>
        <property type="gene ID" value="CP500_003880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006633">
        <property type="entry name" value="Carb-bd_sugar_hydrolysis-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011459">
        <property type="entry name" value="DUF1565"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022441">
        <property type="entry name" value="Para_beta_helix_rpt-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07602">
        <property type="entry name" value="DUF1565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00722">
        <property type="entry name" value="CASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03804">
        <property type="entry name" value="para_beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CASH" evidence="2">
        <location>
            <begin position="89"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="339" mass="34812" checksum="57F947DAF98F3144" modified="2018-01-31" version="1">MATLYVNSVTGSDAAAGSQSAPLKTIARAIGMATAGTIIQLAAGTYSATSGEQFPLDIPSGVKVIGNESNKGSSTIIQGSGKFVSPSAAGQNITILLGTDAELRGVTVTNLESRGTGVWIESTSPTVANCTFTKCKREGIFATGNANPAILDNLFLENSAAGVIMAGSVKGVMRRNIFQNTGFGISLQAQSGPLIVDNQIVQNRSGIVLAGDSQPTLRNNRIEKNLEDGLTVVGKALPDVGTAKDLGGNLFLNNGEFDLQNATGVKIFALGNQINPSLVKGLVDLGAVTPTPTPTPTPTPIPTPTPTPTPTPTPTPIPTPTPTPTPTXSNSNSKRNQIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4W9</accession>
    <name>A0A2G4F4W9_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grpE</name>
        <name evidence="8" type="ORF">CP500_003335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000011">
        <property type="protein sequence ID" value="PHX56843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56843">
        <property type="protein sequence ID" value="PHX56843"/>
        <property type="gene ID" value="CP500_003335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="79"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX56843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="263" mass="29170" checksum="2CC3B0047DC69D9A" modified="2018-01-31" version="1">MIDEEKQPHQDSSSTGETLESPPIASENPPAEANSNAVADWELELAQAYQSSQVDRTAANANGETGTDSSSNSVSADVTELLKRELAQATNDKEGLKAQLQAYSTQLEELKNQNLRLAADFENFRRRTQKEKEELDLQAKCVIIKPLLPVIDNFERARSHIKPQTDGEMNIHKSYQSVYKQMVECLKQIGVSPMRPEGEQFDPNLHEALLSEPTDEHEEGTIIQELERGYTLGDRVLRHAKVKVAAPGSSVLASDENPDSSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F547</accession>
    <name>A0A2G4F547_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_003015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56859">
        <property type="protein sequence ID" value="PHX56859"/>
        <property type="gene ID" value="CP500_003015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013579225" evidence="1">
        <location>
            <begin position="18"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="13394" checksum="043BAC57143B6843" modified="2018-01-31" version="1">MLKLKFLSPLFAPLALASVISVGDVAVHSFLPQFQNTAIAAPEMTVQQKIDIITKSKGQIGSGDQLRRFFYGDLLPLGVQPGGAGMVVNLYNKANDVTFSYCATYDVVVAVKKGKVPMFAAAEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F560</accession>
    <name>A0A2G4F560_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RDD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CP500_003050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000010">
        <property type="protein sequence ID" value="PHX56865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56865">
        <property type="protein sequence ID" value="PHX56865"/>
        <property type="gene ID" value="CP500_003050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13599">
        <property type="entry name" value="Pentapeptide_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="26"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX56865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="710" mass="75619" checksum="8BF0CD9DA5644748" modified="2018-01-31" version="1">MASPTAPSGINQPDPSWQAQSKQMPLLIRRCGAWVVEISLVATSALVPFSIGTLVNREAQTVPLNSSIAAASESVSRSLGIPVRDRNPRVAPLTNLFWSAALMAPAVLAAWQLFLLARTGQTLPKRWFGVKVVTASGTPPGFGRVLIRESFGRWGVPLGLVYGVWRLSGAFPDLIILGGLSGLAMLVDGAFAFRYKGQAGHDRLANTLVVNARSNELSTNPVKSQDWTEEDAQIAALVLTPETSTKENATLWNWIRQHPGIILLTVTIGSAGLILTLFVGTQVYIQSQTNLRDSRQRNDELFVALVNKLSPTSGNGTAGRRSAILALATVEDSRAVPLLADLLAQEESRTMLDAIQQALVSAGPKALPYLQRLNQALSNDLESLRFGGKTQERELAASRQRTVQRAIGKILTLYSSQLNGADLSRTDLGQSPAGSAQFTLVLDKVDLSGIKLKNSNLTNANLPGVRFYGTGEDRRPGTFDDWISDLSGANFEGANLTGANLNSAVMNRTIFVRAVLNKANFSNSNLNLANFSSAILIGANLQQAILKDASFTGADIGSANFSGGNLSGARLGKVKAQGAQLSLTNLEKSEWQGADLSGADLSGANLQKADLSSTKLANANFRDTRLQDANLRNADVSSADFRGANVAGANFKGAVFLGKPGSDQFIETPGAAKSGRLQGVDFTEAKNLDQSQIAYICLQGGLHPKCPQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F583</accession>
    <name>A0A2G4F583_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_004360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000015">
        <property type="protein sequence ID" value="PHX56647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56647">
        <property type="protein sequence ID" value="PHX56647"/>
        <property type="gene ID" value="CP500_004360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="3"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX56647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="148" mass="15860" checksum="F37B8C89BB6FF7BD" modified="2018-01-31" version="1">MRRIFADSSVLIAGCGSRRGASRAVLTMAEIGLFKLVVSDQVLEECDRNIRKKIPAAMPIFTDLLAAINPEIQPDPSLEASSQWAAIIEAKDTPILAAAVLANVDRLLSLNTKDFTAQVAAQSGLIIQTPAEFVTEIREIVGKGLLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5F3</accession>
    <name>A0A2G4F5F3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Excinuclease ABC subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX57002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57002">
        <property type="protein sequence ID" value="PHX57002"/>
        <property type="gene ID" value="CP500_002640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="36"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="122" mass="14018" checksum="E472EE892DCE13DD" modified="2018-01-31" version="1">MPESIQQEAQAILNILASTPFQDCIALSKEFRELPMRAGIYAVKHRSLGILYIGKTRTLRDRFRGGHKALLWAFIEELKATDIRIAFYQLDFTQWIQLSSELESLIIQAVNPPYNVKIPARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5L0</accession>
    <name>A0A2G4F5L0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Alanine dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ald</name>
        <name evidence="11" type="ORF">CP500_002585</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + L-alanine + NAD(+) = H(+) + NADH + NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:18405"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="1.4.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.1" evidence="2 5"/>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX56991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56991">
        <property type="protein sequence ID" value="PHX56991"/>
        <property type="gene ID" value="CP500_002585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000286">
        <property type="term" value="F:alanine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05305">
        <property type="entry name" value="L-AlaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008141">
        <property type="entry name" value="Ala_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008143">
        <property type="entry name" value="Ala_DH/PNT_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42795">
        <property type="entry name" value="PTHR42795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000183">
        <property type="entry name" value="Alanine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00518">
        <property type="entry name" value="alaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00837">
        <property type="entry name" value="ALADH_PNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="10">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="9">
        <location>
            <begin position="148"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="266"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="297"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="PHX56991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="362" mass="38866" checksum="8BAAA9466FDAD7E8" modified="2018-01-31" version="1">MEIGVPKEIKDLEFRVGLSPTSVRACSDRGHTVFVETNAGAGAGFADEDYIQAGAKIVSKPADVWNRELIVKVKEPLPAEYPLIQKEQLLFTYLHLAADRTLTEHLIDSGVQAIAYETVELPDRKLPLLTPMSIIAGRLAVQFGARFLERQQGGRGVLLGGVPGVRPGKVVILGGGIVGTEAARIAVGMGARVQILDVNVDRLAYLETLFGSRVEYLYSSPLQIEAVIPDADLLIGAVLVLGKKAPILVSREFVAKMHPGSVIVDVAVDQGGCVETLRVTSHTNPTYVEEGVVHYGVPNMPGAVPWTATQALNNSTLPYVLQLANSGIKALETNPSLAKGLNVQKHRLVHPAVREVFPDLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5N0</accession>
    <name>A0A2G4F5N0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methylthioribulose-1-phosphate dehydratase</fullName>
            <shortName evidence="1">MTRu-1-P dehydratase</shortName>
            <ecNumber evidence="1">4.2.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">mtnB</name>
        <name evidence="3" type="ORF">CP500_001975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-methyl-5-thio-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15549"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="4.2.1.109"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldolase class II family. MtnB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.109" evidence="1"/>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57070">
        <property type="protein sequence ID" value="PHX57070"/>
        <property type="gene ID" value="CP500_001975"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046570">
        <property type="term" value="F:methylthioribulose 1-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01677">
        <property type="entry name" value="Salvage_MtnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017714">
        <property type="entry name" value="MethylthioRu-1-P_deHdtase_MtnB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640">
        <property type="entry name" value="PTHR10640"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03328">
        <property type="entry name" value="salvage_mtnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aldolase_II" evidence="2">
        <location>
            <begin position="7"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="209" mass="23069" checksum="86AB542F7DA4F13A" modified="2018-01-31" version="1">MSVDLRTDLIVAAKHFYAQGWMVGTAGNLSARLDDGSFWITASGRQKGNLTETDFIRINLDGTIVEQPHPDSRPSAETSIHLAVYNSFPEAQACYHVHSVEANLVSRLAAGDAVSLPAIEMLKGLGVWEENPQVSIPLFTNYLEVPKIAQEICEVFAISPPKVPALLIRDHGVTVWANSPAAAYNYIEIVEYIFRYMMTASQSILDDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5P8</accession>
    <name>A0A2G4F5P8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_001970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57069">
        <property type="protein sequence ID" value="PHX57069"/>
        <property type="gene ID" value="CP500_001970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="8"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="51"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="197"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX57069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="345" mass="38963" checksum="C1950D16AEAF2508" modified="2018-01-31" version="1">MAKYTRILSIDGGGIRGIIPGQVAVSIEEKLQQKSGNPDAKIADYFDLIAGTSAGGILTCLYLFPDPENPTRPRWSAQDAVNVSIKSGRDVFKSSFWQTLTSLDGLVDEKYSSDRLEKFFLEHFGDCQLSELLKPCLITSYDIERRKAHFFDQIDALNHPEEDYFIRDIARATSAAPSYFEVPKIHSLTNESYVLVDGGVFANNPALCAYAEVRNKFRIPEDRADKGPTAKDMVILSLGTGEAQKKYPYEEAKDWGQVEWIEPLISMMMTGVAETVNYQLIQIFDAIERPNQYLRITPNLSLYEEPLPIDDPSEPKLSQLIKIGKEQVEKHNQELDRFIDLLLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5S8</accession>
    <name>A0A2G4F5S8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_001565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57116">
        <property type="protein sequence ID" value="PHX57116"/>
        <property type="gene ID" value="CP500_001565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="29"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="271"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="912" mass="101351" checksum="8F20B023170F6CE5" modified="2018-01-31" version="1">MPDNSQNRPELDLKTIFPFELDNFQREAIVALDAGKSVVVCAPTGSGKTLIGEYAIHQALARGRRVFYTTPLKALSNQKLRDFRQQFGNEMVGLLTGDISFNRDAPILVMTTEIFRNMLYGTPIGAVGASLSGVETVVLDECHYMNDKQRGTVWEESIIYCSGEIQLLALSATVANSGQLTDWINKVHGPTELVYSDFRPVPLQFHFANQKGIFPLLDESGQKANLRLIPKKKQQKVERGSIPVPSLGEVLSRLDDRDMLPAIYFIFSRRGCDQAVAEVANFSLVNQAESAELKRIIDDFLQRNPEAERTGQKEALLKGIAAHHAGILPAWKGLVEELFGRGLIKVVFATETLAAGINMPARTTVISTLSKRTDKGHRLLNASEFLQMAGRAGRRGMDELGHVVAVQTRFEGAKEASYLATAKADPLASQFTPSYGMVLNLLQTHTLDEAQELVERSFGQYLSTLYLQPQQSEVDRLQGELAVLEESLAAGGDVANLEKQLAHYEKLQGTLKEDKRLLKTLWQQAEEARIKEMSVAVAFAVLGTVLSLKGKHVPTAKRSHTNPIPAVLIAKIPGPGQAPNLVCLGKDNRWYIVAISDVATLHAQLPRLSVADTLNPPSEMPMRLGQCRLGTEETLSIAQSIPELPAPEPTREAIEQQQKIAALEAKLEIHPVLAWGNPGTLLKRQRRRTELQNEIRRGLYDLEKQRARYWEEFINLIDILLNFGCLERVVSLNVSGSDTSERLVPTELGQACAAIRGDNELWLGLSLMSAEFDELDPHHLAAACAALVTEVSRPDSWTHYSLSPEVLAPLDNLQKGLRRRLFQVQYRHEAAIPIWLERDIVTLVEQWALGVEWLELVSHTSLDEGDVVRILRRTLDFLSQIPHVPHVSDSLRKNAGRAMHLIDRFPVNEAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5Y6</accession>
    <name>A0A2G4F5Y6_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truA</name>
        <name evidence="9" type="ORF">CP500_001685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000005">
        <property type="protein sequence ID" value="PHX57135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57135">
        <property type="protein sequence ID" value="PHX57135"/>
        <property type="gene ID" value="CP500_001685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="22"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="158"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="280" mass="31829" checksum="48EF86747793653B" modified="2018-01-31" version="1">MIDNPKSQIENPESMQRVALVIQYLGTDFHGWQRQPNQRTVQEEIETAISNVLERPVTLYGAGRTDAGVHAAAQVAHFDACGPIPAHRWASVLNSRLAKDILIRASAKVEPTWHARFSASWRRYRYTLYTDPIANLFVRPVAWHYYHAPVDESKIQAAMEPLIGRHHLAAFHRAGSARPHSWVDVQAAECHRSGPLIYIEVQARGFLYGMMRLLVGLVVQVGRGERAIDDFTDIWVNERRELVKYAAPAQGLCLLRVGYEDFPFAPEVWYDTQPKLVISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F611</accession>
    <name>A0A2G4F611_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000004">
        <property type="protein sequence ID" value="PHX57224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57224">
        <property type="protein sequence ID" value="PHX57224"/>
        <property type="gene ID" value="CP500_001420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="102" mass="11804" checksum="FDE05280A145A1C2" modified="2018-01-31" version="1">MPSAMEEIDRVFTNLVQQWRNETIGISSTTDLVMHPAYQQIIKMGPVVIPLLLREVARKSGRWFWALCEISGEDPVPLEKRGKTKEMTQIWLEWGGAKGYKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F696</accession>
    <name>A0A2G4F696_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BrnT family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_001175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000003">
        <property type="protein sequence ID" value="PHX57280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57280">
        <property type="protein sequence ID" value="PHX57280"/>
        <property type="gene ID" value="CP500_001175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038573">
        <property type="entry name" value="BrnT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007460">
        <property type="entry name" value="BrnT_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04365">
        <property type="entry name" value="BrnT_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="94" mass="10856" checksum="C6314FE22F689FF5" modified="2018-01-31" version="1">MQFEWDENKNAQNLKKHGISFEEAQEIFDGIVFNAIDERFDYGEIREISIGAIQGVVIVTVAHTERNGTIRIISARKATRQEKNTYYDYLAQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6A2</accession>
    <name>A0A2G4F6A2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_002180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57017">
        <property type="protein sequence ID" value="PHX57017"/>
        <property type="gene ID" value="CP500_002180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="78" mass="8518" checksum="9B1B77465B7C942E" modified="2018-01-31" version="1">MLHHRQTALSLGSLGIMLGIASGVRANQISIHPANSTAQFRHIEQPLNLKIGVTAGGLTLIGLELWWFLFSKNKAKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6F7</accession>
    <name>A0A2G4F6F7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YdcF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_000735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57338">
        <property type="protein sequence ID" value="PHX57338"/>
        <property type="gene ID" value="CP500_000735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="78"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="264" mass="28887" checksum="C48BB7E6477F0A97" modified="2018-01-31" version="1">MFVFLSKLLPLFIYPLGLSCLLIVAALTMLWKRPKWSALPMAAALIILLLGSSGWVSKSLVRSLEWQNLPMAETPQADAIIVLGGGVKAALPPRPWVELGEAGDRIIYASRLYRQGKAPLLILSGGRVEWKGGGSPESADMAEIAQTSGVPASAILQDPDSNNTYQNAVNVRKILDTKNIKGPVLLVTSAMHMTRSLLIFQRQGIKAIAAPTDFHITQRDMTVAQSNWQAVILNCLPDSYQLHQSTTALKEYIGLIVYRLLGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6J7</accession>
    <name>A0A2G4F6J7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_000080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57378">
        <property type="protein sequence ID" value="PHX57378"/>
        <property type="gene ID" value="CP500_000080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010802">
        <property type="entry name" value="DUF1400"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07176">
        <property type="entry name" value="DUF1400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1400" evidence="1">
        <location>
            <begin position="29"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX57378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="191" mass="21292" checksum="E08908232D9547C1" modified="2018-01-31" version="1">MRWSFFKRRWRLFLATGAGILFYSTAAVASEKVVLKYSVIRMTLPVSELEIFAETGKMSPALEMLLGQAKKDPELVRRSLTKPVKVSQRLLDRTLNSKVGDLILDEVGQVIRTPSGNANKEALRAALVLSATSDNQITLLETIKNYPTTEVYVEGDRLVEAYGKLVALSEQLGGVSEQLQDVLNKIRLPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6L0</accession>
    <name>A0A2G4F6L0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_000820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000002">
        <property type="protein sequence ID" value="PHX57355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57355">
        <property type="protein sequence ID" value="PHX57355"/>
        <property type="gene ID" value="CP500_000820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="89" mass="10220" checksum="E02FF1FEC6E65027" modified="2018-01-31" version="1">MSERELLIREIAQTSDTLVTELLNFLLFIKSRKIQNDFQNPNSENSDLPSFLNFIDLINSETPAEENAQLPIDLSKNLDSYLYGSPKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6Q3</accession>
    <name>A0A2G4F6Q3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CP500_000430</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MlaE permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57436">
        <property type="protein sequence ID" value="PHX57436"/>
        <property type="gene ID" value="CP500_000430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="PHX57436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="265" mass="27932" checksum="72C899A5994FC8AF" modified="2018-01-31" version="1">MLLNPTSSSLSLWSRRLLAAILLGGQVMLHLLTRKINRRNTLDQMAAVGPESLLIALLTAGFVGMVFTVQVAREFINLGAGNVVGGVLALSLTRELGPVLTAVIVTGRVGSAFAAEIGTMQVTEQIDAMLMLRTDPIDYLVIPRVIACCLMLPILTILSLVTGIAGGLLIATTMYGVSQTVFLESVRNFLTLWDICSAIIKAFVFGGLIAVIGTSWGLTTTGGAKGVGQSTTTAVVTSLLAIFILNFVMTWVMFQGTGSSVLKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F6T8</accession>
    <name>A0A2G4F6T8_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease PH</fullName>
            <shortName evidence="4">RNase PH</shortName>
            <ecNumber evidence="4">2.7.7.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA nucleotidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rph</name>
        <name evidence="7" type="ORF">CP500_000195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>phosphate + tRNA(n+1) = a ribonucleoside 5'-diphosphate + tRNA(n)</text>
            <dbReference type="Rhea" id="RHEA:10628"/>
            <dbReference type="Rhea" id="RHEA-COMP:17343"/>
            <dbReference type="Rhea" id="RHEA-COMP:17344"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:173114"/>
            <dbReference type="EC" id="2.7.7.56"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexameric ring arranged as a trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.56" evidence="4"/>
    <dbReference type="EMBL" id="NXIB02000001">
        <property type="protein sequence ID" value="PHX57451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57451">
        <property type="protein sequence ID" value="PHX57451"/>
        <property type="gene ID" value="CP500_000195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009022">
        <property type="term" value="F:tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11362">
        <property type="entry name" value="RNase_PH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00564">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002381">
        <property type="entry name" value="RNase_PH_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018336">
        <property type="entry name" value="RNase_PH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01966">
        <property type="entry name" value="RNasePH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01277">
        <property type="entry name" value="RIBONUCLEASE_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="RNase_PH" evidence="5">
        <location>
            <begin position="13"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_PH_C" evidence="6">
        <location>
            <begin position="160"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate (substrate) binding" evidence="4">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="PHX57451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="239" mass="26191" checksum="B758F6FF643993B6" modified="2018-01-31" version="1">MSIKRADGRQPNQLRPISFDREFTKFASGSVLAKSGDTQVLCSVTIKPGVPRFLENTGKGWLTAEYRMLPGATPQRQEREFMKLSGRTQEIQRLIGRSLRSCLDMELLGERTIIVDADVLQADAGTRTTSINGAFVAVADALNKLVQKGDLVRSPLVRQVAAVSVGLLEGELFLDLNYLEDVAAEIDCNVVMNGDLNIIEIQGTAEEGSFSRSQLNQILDLAEIGIQELLEAQRQALGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EUC8</accession>
    <name>A0A2G4EUC8_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40 repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_023045</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000261">
        <property type="protein sequence ID" value="PHX53153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53153">
        <property type="protein sequence ID" value="PHX53153"/>
        <property type="gene ID" value="CP500_023045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="150"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="192"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="234"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="276"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="318"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="360"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="402"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="444"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="486"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="528"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="570"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="625"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="667"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX53153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="742" mass="80797" checksum="CBCA611579935B66" modified="2018-01-31" version="1">MSEFTQESNPILPAEQMPCLEILPSQPAAPGEADRLYSLLTDYNFIEAKLSASGVQPLIEEYDLATKSEISTSNQKAETLKLIQETIRLSAHIIAKDKTQLATQLIARLMCFENPEIQALLTQAKHQKKPWLRPLTSSFIAPGGRLQRTLTGHTDWVQAVAITPDGKRAISASSDHNLKVWNLETGEELFTLTGHLTYVNTVAVTPDGTQVISGSWDNTIKIWNLKTGQEVFTFAGDTFAVEAVTVTPDGKAVISGSWDGSIKVWNLTTREVIFNLKGHTSFVQSVAVSPDSKRLISGSGDNSIKVWNLETGKELFTLTGHTDWVKSVVFTPDGKNIVSGSYDGTVKVWTLAERKRVFALGTHDSFVQAVAVTTDGKRVISASGDKTIKVWDLEAREELFSFTNHIAPVNAVAVTPDGKRIVSGSSDKTLKVWYLETGKENLSFVGHEDSVNAVVVTTDGTKVISGSGDNSIKIWNLENGEEIFTLIGHQDWVKAIAVTPDSRRIISGSGDQTVKVWNLETGKEIFTFTGHTDWINAVAVTADGTMAISGSGDKTIKLWNLETGEEIFTFTGHTDGIKAVAVTPDGKQLISAAGDKTLKVWSLGKEKNIFANVWNLVVKNQLFTLKGHESLINALAVTTDGKWAISGGRNKMIKVWDLSSRKELFTLAGHADAVTALATFGTKLISVSDDNTLKVWDLLSREVIAIFRGDSAFKSCAFAPDGVTIVAAEVSGQMHFLRLENC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EVC4</accession>
    <name>A0A2G4EVC4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_021260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000191">
        <property type="protein sequence ID" value="PHX53484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53484">
        <property type="protein sequence ID" value="PHX53484"/>
        <property type="gene ID" value="CP500_021260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013861759" evidence="2">
        <location>
            <begin position="22"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="125" mass="13554" checksum="89BE0B5661CEFD30" modified="2018-01-31" version="1">MNSKISKPGILMIRVALSAIASSTLFLPQATFAQASSLNNSQPLQDFQTNDNPDPFSGSSGTGVFDLIHRSRLGNGRSIEEFSTEQRQNLNDAATEFRNKQRLLLEKPAVPSPEATPTEITAPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWC5</accession>
    <name>A0A2G4EWC5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_019350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000150">
        <property type="protein sequence ID" value="PHX53834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53834">
        <property type="protein sequence ID" value="PHX53834"/>
        <property type="gene ID" value="CP500_019350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014056">
        <property type="entry name" value="Addiction_killer_pred"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41791">
        <property type="entry name" value="PTHR41791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028744">
        <property type="entry name" value="Addict_mod_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02683">
        <property type="entry name" value="upstrm_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX53834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="13089" checksum="3E7A6AC0777D9CED" modified="2018-01-31" version="1">MEAQPREVQNYLKTDGTSPFEGWLDSFQDTKTVSKIKKRLRRVELGNLGDYRSLGAGVFELKIDYGPGYRIYFGQIGLTVVLLLCGGDKSTQEQDINQAKKYWRDYERTQSANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EWJ0</accession>
    <name>A0A2G4EWJ0_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HEAT repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_019095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000144">
        <property type="protein sequence ID" value="PHX53889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53889">
        <property type="protein sequence ID" value="PHX53889"/>
        <property type="gene ID" value="CP500_019095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030089">
        <property type="term" value="C:phycobilisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0042">Antenna complex</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0605">Phycobilisome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013888679" evidence="5">
        <location>
            <begin position="26"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX53889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="386" mass="43193" checksum="87668AD0F36B536E" modified="2018-01-31" version="1">MAQYRSTFLLFACIASLGAAFSPNADGRQQVLNLSYRDFSPEIAQGNSPSDDRPNSNTPKPSPKADRSKSKPSQTKKTNSKDPKSISNLIVMLSRQRGLLILGFAAVVITAAAVFIMLKLVGSDESNNSKRRRGRVEHHKPRNTQFPNPDTQTNFNESRRGVSFGTGEPQPALTHSSDFSKIYNLDSGESEETGVESDRLNSDILSVETNSNGLYSDTDFNVYQKNHLPDSKANLTKDIFIPEDDDRSKLDIIEALIEDLQQLNPAMRRKAIWELGQQGDSRAVEPLLDLLANSDSKQYSLILASLSEIGIRTLKPMNHAWSISLQNQNPEVRKNAIRDLTRIYELVNQITHLLHRATDDPDPEVQETARWAINQLNCIHPRSTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EXI5</accession>
    <name>A0A2G4EXI5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_019210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000147">
        <property type="protein sequence ID" value="PHX53867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX53867">
        <property type="protein sequence ID" value="PHX53867"/>
        <property type="gene ID" value="CP500_019210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="10"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX53867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="349" mass="38963" checksum="2692F5032F317548" modified="2018-01-31" version="1">MIYTADPTVSVIIPVHNGGAYFRTCLSKLAQAVPRPIEIIVVADGDSDGSWRLAKEFGAKLIRIPESGGPARARNLGAQAAKGDILFFVDADVAVCPEAVGYAISVFKNNPYLAAAIGSYDDAPGDPGFLSQYRNLMHHYVHQTGNEEASTFWGACGLIRREIFLKMGGFNESYRRPSIEDIELGYRLKQAGYKIRLCKTLQVKHLKRWEAISLLRADFFYRALPWTELIWRDRKLNNDLNLQVSSRVSIVLTYAMLLSILGTWWSLGCLVLASLLAIPLVVINAPLYRFFGSKHGMIFAIKTIPWHWLYYFYSGLGFAIGTARHLLSQKKSLTLKISLPASAQSLKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYH6</accession>
    <name>A0A2G4EYH6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArsR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_015655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000094">
        <property type="protein sequence ID" value="PHX54528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54528">
        <property type="protein sequence ID" value="PHX54528"/>
        <property type="gene ID" value="CP500_015655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX54528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="114" mass="12859" checksum="94DB50061CB4E3D2" modified="2018-01-31" version="1">MSQIPVSALAQIADYFKVLSELSRLQVLCALKNGAKNVTEIIEETGLGQANVSKHLKILTQAGIVQRQPQGVSVYYQITDPMIFDLCEVVCQKLETRLHQQSQHLKKLDRLRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EYP2</accession>
    <name>A0A2G4EYP2_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hybrid sensor histidine kinase/response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_015020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000087">
        <property type="protein sequence ID" value="PHX54633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX54633">
        <property type="protein sequence ID" value="PHX54633"/>
        <property type="gene ID" value="CP500_015020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="389"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="662"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="473"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX54633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="1078" mass="118428" checksum="5DCF2946D974D31B" modified="2018-01-31" version="1">MPQTRSTLQDFIEPVPLCRSTAQLKTLRSIFSQGNCDRIAVVNEQLQPLGLVYLRSLMPLADRDSKWQQPLSEKPIAIAPLTTISGDLSVSEFWQYLQTTELHTPEQRGETEGKYFDRPIALTNSEGKFLGLLNSLSLLQFVALNSSSIKHSTASEYSLKAQQTAAKEHGHSPAQSVITTALDAQLRFLEAGLKPSENLNSLVQLLEKLPLPLRLQTPTGQIVSQNAPWRTLLGAGPEPVAETDNEPAVNPHRPSPHKPGREATEYKSAPNLDLTQEFSSLVGVARSGDRDSTTATSCPLPLYAAASPSTLTSPAWCLTPGKPDTYICDCPVQKGQERIWQFVKQPLSDNLILVMGQDVTEEHLVAKELAAKNADLIHLNRLKDEFLSCISHELKTPLTAVLGLSSLLKDKLIGELNDRQTRYAKLIHKSGRHLMTIVNDILDLTRMETGQLELIPEPVEITAACNRAFEQAKQLQQQDEKSPSKSEVTTANQEVESSAETEFTLEIEPGISYLIADELRLRQMLVNLLSNALKFTEIGGKIGLKVNIWEGWIAFTVWDTGIGIPADKQHLIFQKFQQLESPLTRRFQGTGLGLVLTQRLARLHGGDVSFISSEGQGSQFTLLLPPNPPGSSIEESAEYTALDPELFKPKYQYPIANSRSRLVLIVEAVPKYIEDLTNVLTGLGYQVIVARSGTEALEKARRFSPEVIFLNPLLPLLSGWDVLTLLKSDPDTRSIPAIVTATRGEKERASVNLAEGFLSLPVTEPALRILLGDLIGHDTNARNVRSSLTILWLSPQNSSSQGSSLLLNHNYCRVLEADDLGQAELVARIWRPDVIVLDGTNPLENPSAFIKQLSLSRSLGSLPLVTLDPATTLLANQVKGLSVFPCLATSNVTSDTPLVASALWQVIQVAAGMSWKPSILFADISTLSDLAGTGENRDTDEVQNCDCRSTNIEFPIPSSEFFLPNFQALIQYIQTAGFRGTIGLRWKEVLQQLQYQSVDLVLLCLRDAPSESSAMLQALSNLRQMTGKPPILVLDYRSVATSESEAIDFLLQEVSAKILPSSLSAAQLLDRIQQSIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4EZT0</accession>
    <name>A0A2G4EZT0_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase</fullName>
            <shortName evidence="8">FBPase class 2/SBPase</shortName>
            <ecNumber evidence="8">3.1.3.11</ecNumber>
            <ecNumber evidence="8">3.1.3.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">glpX</name>
        <name evidence="10" type="ORF">CP500_013095</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-sedoheptulose 1,7-bisphosphate + H2O = D-sedoheptulose 7-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17461"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:58335"/>
            <dbReference type="EC" id="3.1.3.37"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">Carbohydrate biosynthesis; Calvin cycle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 8">Belongs to the FBPase class 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="8"/>
    <dbReference type="EC" id="3.1.3.37" evidence="8"/>
    <dbReference type="EMBL" id="NXIB02000069">
        <property type="protein sequence ID" value="PHX55012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55012">
        <property type="protein sequence ID" value="PHX55012"/>
        <property type="gene ID" value="CP500_013095"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00116"/>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050278">
        <property type="term" value="F:sedoheptulose-bisphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019253">
        <property type="term" value="P:reductive pentose-phosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01516">
        <property type="entry name" value="FBPase_glpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004464">
        <property type="entry name" value="FBPase_class-2/SBPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30447">
        <property type="entry name" value="PTHR30447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03320">
        <property type="entry name" value="FBPase_glpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004532">
        <property type="entry name" value="GlpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00330">
        <property type="entry name" value="glpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0113">Calvin cycle</keyword>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR004532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR004532-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="PHX55012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="345" mass="36777" checksum="5FB907D569C04E0F" modified="2018-01-31" version="1">MDNVIGLEIIEVVEQAAIASARLMGKGLKDEADSVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKDVCNLDELIEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMNKLAAPAAAKNHVDIRKTPTENLKIISDCLGRSVEDLVVVVMDRPRHKDLIAEIRQAGARVRLISDGDVSAAISCAFSGSNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPAVVKTGLIGESKESNIARLTAMGITDPDKIYNAEELASGETVLFAACGITPGTLMDGVRFFGGGARTESLVISSQSKTARFVDTIHMFDQPKSLQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F0T1</accession>
    <name>A0A2G4F0T1_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I-D CRISPR-associated helicase Cas3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cas3</name>
        <name evidence="2" type="ORF">CP500_011225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000055">
        <property type="protein sequence ID" value="PHX55362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55362">
        <property type="protein sequence ID" value="PHX55362"/>
        <property type="gene ID" value="CP500_011225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017575">
        <property type="entry name" value="CRISPR-assoc_helicase_CYANO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03158">
        <property type="entry name" value="cas3_cyano"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="37"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="757" mass="86124" checksum="BB4B72D97A951F7A" modified="2018-01-31" version="1">MDNLKIKLEPASISACPKLPQPLEFMEQALQHQVDVYEASENNDIILDLAPTGTGKTKAGLSVLLHNSQRNAIYIAPTNALIDQQTEAAEKFVRDARLPHLVKAASARQVHSWPDNRVGKRSGEKIYNVLREPATIFPECGGGRPILLVTNPDIFYYATFFAYNNLDRGNIASEFYSSFSTVIFDEFHLYDAKQLVSLFFYLALSKEFGYFQYKRKIVLLTATPEPACEEALNVLGKNGVKIARIDGKSQISHLRPSQTEVNLEIRKQVDKETTIAEIVQEVLRRLRENPDQNGAVILDAKDTLGRISDQLRDRGFADNCGRITGDTPKEKRALAAQKQVILATSTVDVGFNFDRDNPPPRQNLDWLIFSTRDRFSFWQRIGRVGRVLGKTQTEIPSEAIAYLPDRAWEQGIAQLDCSGGRNSLTEMLESLECMKRPFLDIYWRSEAFLEIAKPLLELEILFDKLPEASLVTQLYQTLQIVLGGKRDWNCYRKRMKVLQGAENVAKSTIKQIQKEWQYIKGGQNCVKSFMQANYPEDWEEIDSGRSSIELIEEKICKNQKIAEKFKEYAMILKASYAPLFKFRESLFENVKIYDPHNFLLDEVGETNLDPIHLLRFFEFASDENGIVLTHRAAQTYGLKFALQVADLEEFANNYLCKLYAFKNCTIERTIGDIVRPTALISQLSPPLMPGVIVQEHRKNRWAIIKLKKQGIECYSITVKDSFAAKEYTFFPSLSGILAIASAGITLRCPDNQEFWVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1M6</accession>
    <name>A0A2G4F1M6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CP500_009690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000045">
        <property type="protein sequence ID" value="PHX55670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55670">
        <property type="protein sequence ID" value="PHX55670"/>
        <property type="gene ID" value="CP500_009690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019250">
        <property type="entry name" value="DUF2227_metal-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39085">
        <property type="entry name" value="PTHR39085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09988">
        <property type="entry name" value="DUF2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="PHX55670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="232" mass="26705" checksum="ED2073649CC86FD9" modified="2018-01-31" version="1">MPSGRTHDRITLWTLPFVAALTFAHTQSSNLTLLVSGSFLFGGLMFGPDLDIYSCQYQRWGWFKLIWLPYQKNLRHRSLVSHGPLIGTALRILYLATWIGVFGILGLVIAEKIGNLAGNWQDVVLGCWRSIVQHPIELLAIYIGLELGAMSHYLSDWGGSAYKRFKKQEGRRKKEEGXRSGYKEGRRKKALRLRSGYKEGRRKKALRLRSGYKERRSNKALRLRSGYKCYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F1U3</accession>
    <name>A0A2G4F1U3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA/RhaT family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_009485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000044">
        <property type="protein sequence ID" value="PHX55716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55716">
        <property type="protein sequence ID" value="PHX55716"/>
        <property type="gene ID" value="CP500_009485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="33"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="183"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX55716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="329" mass="35843" checksum="D4A238269C1418DA" modified="2018-01-31" version="1">MSTHLLKSMTAKLELAQQPLSRTPTWIATASLFASLIPLSLAPILVKLCEREIGSNAVAFHRGWIATIIFGLLSGLEALDRQKSDNQPVEQKPFTRRELGLLVALGTFGAIYFLLWSLALTQTNVANVTLFCGLNPLFVGLGGWLLLGRSYNSRFIIGMIMALGGAIAMGLDDVQFATNQVQGNALALLSGICFAAYLILLELLRERFTTATLLLWRCAFTTMLAFPVLALAQETLFPHSWLGWFFVILQAVLCQVLGQGLLAYSLSKLSSGFVAVTLLFEPVLASIFAWVIFSERLGFLDLVAFVVILCGIYVAQSSQSAVKETSEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F274</accession>
    <name>A0A2G4F274_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_008415</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OprB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000038">
        <property type="protein sequence ID" value="PHX55849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX55849">
        <property type="protein sequence ID" value="PHX55849"/>
        <property type="gene ID" value="CP500_008415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038673">
        <property type="entry name" value="OprB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013427623" evidence="2">
        <location>
            <begin position="29"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="5">
        <location>
            <begin position="197"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="146"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="155"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX55849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="711" mass="75098" checksum="BCEFFE02C2C69883" modified="2018-01-31" version="1">MSKFLWNYLLISPAVLGATLVVSSSAIAADAQTAADASRTQTAKTAITEISEAKLNALAAVPSGTATQTIEEISQVPVSEIQSANAATDAKAVTDNNAIAANTATETASEPNTASLAAVEPTVVQQQATPAAVVVQPETTVPTVVAESAQPSLPKPAESVAQTTAPATQNSNATLEQLSQYSTEGAAESETQGQVTSVSQLSDVRPTDWAFQALQSLVERYGCIAGYPDGTFRGNRAMTRYEFAAGLNACLDKVNELIKAGTTNLATKQDLAALQRLQEEFAAELATLRGRVDSLEARTSELKANEFSTTTKLTGEAIFALSDDFGGSAGFFGRDRTRIGSNQNEAVFQQRVRLNLNTSFTGRDLLLTRLQVGNGRNFNFGATSEGTQTWNVVGNTAANVFALDSLLYKFPVSQRLNVTIAANGGVWDDIIPTVNPYFEDYDGGNGALSTFGQRNPIYRLGGGAGIGFDYAFGGRGLLGGVFGPTSLSFGYLASNAANPAKGAGLFNGDYAAMGQLTFTPGRNLQVGLNYNYGYFSRGNFGFDNGLRNGPGQLGGFTGTGVANSINGLSEGFKGFASRKVVSNSYGAQASFRLSPRFIVGGWAGLTNARVIGIGDARIWNYAVTLALPDLGKEGNLLGFVVGREPYLDKLEAAGNLGNFTNNTSWHLEGFYKYQLTDNISVTPGVVWITNPNQDRANNDVIIGTLRTTFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F2X4</accession>
    <name>A0A2G4F2X4_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_007290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000031">
        <property type="protein sequence ID" value="PHX56102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56102">
        <property type="protein sequence ID" value="PHX56102"/>
        <property type="gene ID" value="CP500_007290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="166" mass="18603" checksum="A03E6A59010BD500" modified="2018-01-31" version="1">MCIGQPDSPACKAVTGMMITDLEKITDHMSQLIIEIKRNSPILDNPKPPRIDDRFAMAEAPSGNRLIIESVDTEDEKFSDDDNFYDLDLVIKDKSANLGAVIVDLIVTNQVGDNPERIRGIRLKIARFVKDLKALEIADIKPEIKKEISDRMKATMSAILEEILTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F373</accession>
    <name>A0A2G4F373_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CP500_006570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000027">
        <property type="protein sequence ID" value="PHX56223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56223">
        <property type="protein sequence ID" value="PHX56223"/>
        <property type="gene ID" value="CP500_006570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="85"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="PHX56223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="201" mass="23266" checksum="B02B189362924F54" modified="2018-01-31" version="1">MIDLYTFTTPNGRKVSIMLEEIGLPYNVHVIDIRKNDQFSPEFIAINPNSKIPAIVDRDNGITVFESGAILIYLAEKIGRFLPTDKEKYFQVLEWLMFQMASVGPMFGQLNHFKRFAPEPIPYAIQRYEKETLRLYGVLDNQLAKYEYICGDYSIADIATYPWVAIYEFQGLTLDNHPHLKRWVETLQKRPAVQRGMAIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3P5</accession>
    <name>A0A2G4F3P5_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000021">
        <property type="protein sequence ID" value="PHX56379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56379">
        <property type="protein sequence ID" value="PHX56379"/>
        <property type="gene ID" value="CP500_005545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="328" mass="35465" checksum="2B85F320CA4DEA35" modified="2018-01-31" version="1">MFAQFRAIYPTGQLICELLTVHHGKFVVRCLVQVDAKTLATGMSAAESIEEAEDRARLRAIALLGLDAAQPAIAPVASSTVSVVPVAIPAPVAVVPVAAPVAPVPVPVAAPAPIALPVLELPLTTDNFAVSHQSSFVNTQSPLIEEPIAPAPISDPLPPMVDRSVAGSRQEFDSDAWLSSSYGEPRSEAPVSTSSQTEFLQSAAEVRELEPISVGIPSDAIEDISETIAQIEAILKRLKWTKKQESDCLQQSYGKMSQGLLSAAELLDFVDYLQIYSKTTDEIKRLSWSPNRGKDYLKQGYGKEARHFLSKEELLDFLQYLESLPSDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3Q1</accession>
    <name>A0A2G4F3Q1_9CYAN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_005865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000022">
        <property type="protein sequence ID" value="PHX56368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56368">
        <property type="protein sequence ID" value="PHX56368"/>
        <property type="gene ID" value="CP500_005865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="2">
        <location>
            <begin position="15"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX56368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="233" mass="27503" checksum="A883FE6E93F845C5" modified="2018-01-31" version="1">MFVTAELATSQDIPKRVIFPTGDLYSDEPPLETELHLRQIILLLQCLDWLWRDRNDFYVAGNLTIYYSQNQRKSEDFRGPDFFVVHGTDRKPRKSWVVWEEEGKYPNVIVEMLSPTTANTDREFKKKLYQDIFRTPDYFWFDPYTLEFAGFHLVDGEYQPLPENSSGHLWSQQLNLFLGIHQKKLRFFTASGELVPTPEESADFERQQKEFAQQRADRLAAKLRELNIDPDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F3X3</accession>
    <name>A0A2G4F3X3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">UbiD family decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_005180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000019">
        <property type="protein sequence ID" value="PHX56483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56483">
        <property type="protein sequence ID" value="PHX56483"/>
        <property type="gene ID" value="CP500_005180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="PTHR30108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01977">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00148">
        <property type="entry name" value="TIGR00148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="502" mass="55539" checksum="F1404A4F33E5C9E9" modified="2018-01-31" version="1">MARDLRGFLKLLEERGQLRRISALVDSDLEIAEISNQMLQKGGPGLLFENVKGAEFPVAINLLGTEQRVCWALNMEKPIELEELGKKLGMLQQPKPPKKISQAIEFGKVLFDVVKAKPGRDFFPACQQVVFEGEGLDLNKIPMIRPYPGDAGKIITLGLVITKDCETGTPNVGVYRLQLQSKNTMTVHWLSVRGGARHLRKAAQAGKKLEVAIALGVDPLIILAAATPIPVDLSEWLFAGLYGGSSVQLAKCKTVDLEVPADSEIVLEGTITPGEVLPDGPFGDHMGYYGGVEDSPLVRFNCMTHRKDPIYLTTFSGRPPKEEAMMAIALNRIYTPILRQQVSEIVDFFLPMEALSYKAAIISIDKAYPGQARRAALAFWSALPQFTYTKFVIVVDKNINIRDPRQVVWAISSKVDPVRDVFILPNTPFDTLDFASEKLGLGGRMGIDATTKMPPETEHEWGKPLESDPDMTAMVQRRWAEYGLADLNLGEVDPNLFGYEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F466</accession>
    <name>A0A2G4F466_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetolactate synthase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CP500_006345</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000025">
        <property type="protein sequence ID" value="PHX56277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56277">
        <property type="protein sequence ID" value="PHX56277"/>
        <property type="gene ID" value="CP500_006345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="5">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="3">
        <location>
            <begin position="187"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="4">
        <location>
            <begin position="378"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="PHX56277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="545" mass="59247" checksum="FDF7B82929B36612" modified="2018-01-31" version="1">MNTAQLLVKCLENEGVEYVFGLPGEENLEVLEALRNSSIKFITTRHEQGAAFMADVYGRLTGKAGVCLSTLGPGATNLMTGVADANLDGAPLVAITGQVGTDRMHIESHQYLDLVAMFAPVTKWGAQIVRPGTTPEIVRKAFKVAQSEKPGAVHIDLPENIAAMPVEGEPLTKDNREKTFGAYQSLNKAAVAISKAKSPLLLVGNGTIRANASDALTEFATRLNIPVANTFMGKGVIPYTHPLALWTTGLQKRDYISCAFEETDLVIAVGYDLIEYSPKKWNPDGKIPIIHIGALPSEIDSSYIPIVEVVGDISDSLNEILQRADRTGKADPFAKQLRADIRAGYEQYSSDDGFPIKPQKIIYDLRQVMGPDDIVISDVGAHKMWIARNYHCDRPNTCLISNGFAAMGIAIPGALAAKLVYPDRKVVAATGDGGFMMNCQELETALRVGTNFVTLIFNDGGYGLIEWKQEDHFGHSDFVKFGNPDFVKFAESMGLKGYRVEAASDLIPILKEALAQDVPCVIDCPVDYRENARFSQQSGDLSCNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F4T9</accession>
    <name>A0A2G4F4T9_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_003425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000012">
        <property type="protein sequence ID" value="PHX56792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX56792">
        <property type="protein sequence ID" value="PHX56792"/>
        <property type="gene ID" value="CP500_003425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX56792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="65" mass="7196" checksum="76ACFB870C9E690B" modified="2018-01-31" version="1">MSTENNVNIKPATRNHKGFFIQPASYKLMSIDKSGWALICIDKAVCHYVDPDDLQLPNKSGTSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5K6</accession>
    <name>A0A2G4F5K6_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3326 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CP500_002390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000008">
        <property type="protein sequence ID" value="PHX57005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57005">
        <property type="protein sequence ID" value="PHX57005"/>
        <property type="gene ID" value="CP500_002390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021763">
        <property type="entry name" value="DUF3326"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36891">
        <property type="entry name" value="PTHR36891"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11805">
        <property type="entry name" value="DUF3326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="PHX57005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="415" mass="43894" checksum="33B8E33D2C9E233E" modified="2018-01-31" version="1">MLRPFTVVLIVPTGVGASIGGFAGDALPVARAIAQVSDTLITHPNVLNGAQLYWPIPNALYVEGYALDKFAQGCWGLQPVHQNRIGLILDSGIEPELQLRHLQAVDASRATLGLNITDYVQTDAPLNVELRMSESGASWGTIANPDSLLRAAEKLITQAKVQAIAVVARFPDDIGSLALENYRHGKGVDPLAGAEAVISHLIVRTFKIPCAHAPALLPLPLDPHLSPRSAAEEIGYTFLSCVLAGLSKAPQFVTPTVGQASCLSVVLDGQDARATQVLDGQDARATQVLGGQDAHPTRENFYANRRDFQSHGLWADRVDAVVIPATACGGSAILSLSGRSAVQIIAVGDNKTQMQASPEKLRIKALQVNSYLEAIGVLVALRAGISPVALGADISPLRCLSDSTKQISNLKSKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5L7</accession>
    <name>A0A2G4F5L7_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CP500_002340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000007">
        <property type="protein sequence ID" value="PHX57046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57046">
        <property type="protein sequence ID" value="PHX57046"/>
        <property type="gene ID" value="CP500_002340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07484">
        <property type="entry name" value="Peptidases_S8_Thermitase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045986">
        <property type="entry name" value="DUF5942"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017295">
        <property type="entry name" value="Pept_S8A_subtilisin_cyanobac-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034084">
        <property type="entry name" value="Thermitase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19366">
        <property type="entry name" value="DUF5942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037851">
        <property type="entry name" value="Subtilisin_cyano"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013606035" evidence="6">
        <location>
            <begin position="26"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="421"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="135"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5942" evidence="8">
        <location>
            <begin position="399"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF19366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="PHX57046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="589" mass="62661" checksum="A7F73A50D94FFE8F" modified="2018-01-31" version="1">MKKFFLLCLFLIGLGWAISSFPGLATQGSYDSIVLDFREDVGNAEIAKQVESIAQKYQITPQLNSEFSKGDNVYVVKGDRTLLDALKKSNLAKDTEYIEPNYVYSKFEIPNDPMYNKQWNLRSINVESAWNETKGSGTTVAIIDTGITPVADLKETKFVPGYDFVNDRAEAFDDNGHGTHVAGTVAQSTNNNYGVAGIAYEAALMPLKVLSGSGGGTVADIAEAIKFAADNGADVINMSLGGGGESQLMEEAIDYAHSKGVVIIAAAGNSGDSSASYPARYPHVIGVSALGPDDEKADYSNFGAGVDIAAPGGSESGKIIQSTIDPETGAEIFAGYQGTSMASPHVAAVAALVKASGITEPDEIRSVLLQSARVVSEDPLNHFGAGNLDAAAAVQLAQRGQINFRDFFRWLRDNGYLSPRFWIDGGAVALLPKIGMVIGSYLLAFLLRNYFPFAWTWGFSGGLVAGSSGLFFLRNLFVFDLPQWPLRVMGSSIPELGGAINGSSLLNPIFASVLIPGILIVLLLGHREWKWMAIATSIGFASSLAVNAFVSPGVWGLGSGLISQSFLIVNALLCFGLARLAMKTEVRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-01-31" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2G4F5N3</accession>
    <name>A0A2G4F5N3_9CYAN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CP500_002110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tychonema bourrellyi FEM_GT703</name>
        <dbReference type="NCBI Taxonomy" id="2040638"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Cyanobacteria</taxon>
            <taxon>Oscillatoriophycideae</taxon>
            <taxon>Oscillatoriales</taxon>
            <taxon>Microcoleaceae</taxon>
            <taxon>Tychonema</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Banno H."/>
                <person name="Chua N.-H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2017-11" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi isolated from alpine lentic freshwater.</title>
            <authorList>
                <person name="Tett A."/>
                <person name="Armanini F."/>
                <person name="Asnicar F."/>
                <person name="Boscaini A."/>
                <person name="Pasolli E."/>
                <person name="Zolfo M."/>
                <person name="Donati C."/>
                <person name="Salmaso N."/>
                <person name="Segata N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">FEM_GT703</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NXIB02000006">
        <property type="protein sequence ID" value="PHX57094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="PHX57094">
        <property type="protein sequence ID" value="PHX57094"/>
        <property type="gene ID" value="CP500_002110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000226442">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PPA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="PTHR22953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="168"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="PHX57094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000226442"/>
        </source>
    </evidence>
    <sequence length="593" mass="67514" checksum="60A129BC15316180" modified="2018-01-31" version="1">MFTPLPEPRENLRKSPRNPWFFAILLAIVLLLGLIMKSHLNKPQLLTDPFLQLPTVNSVRVVWFTEFAGISNKVIYGEELSQSVTANTTKLSRTREDKDSYISDQRKHGIVDNNSIVRDIWRHEAKVANLIPGVTIPYLVTSDREDNESVSSKIFTLSPTPTAGVTLQILLTSDHQLMPMTAANLQKVAETIGKVDAVFMAGDLINIADRASEWFDDLRGRAFFPCLQGRGFSQLDKNGTQTVYTGGELIQHAPLFPAIGNHEIMGRFSTISKLNDQFNDPFPRAAAEKIYQSKTQKSAVTDKDNWLKNNTFNSDTYNEIFTLPGNKNYYAVTFGDVRLVTLYITNIWRTPNLDPGAKGRYRERNEDFNNFEKWGYGQHIFEPIAKDSPQYNWLQKELNSPEFQQAKYKVVMFHHPPHSLGDNIVPAYTDPVQIVDRDEQGNIKMVRYEYPKKQDYIIRDVIPLLEKAKVQLVLYGHSHLWNRFVSPSGMHFLETSNVGNSYGAFFGKKRRFVPPAYREDYTAIGDPNGLNPVIPTITPLLEDGQPLPYIDSNDITAFSIFDTGDGVVSSYYFDTRKPESEVVKFDEFKLKNS</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>